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Search of human proteins with 28912912
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28912912 NK6 transcription factor related, locus 2 [Homo
sapiens]
(277 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28912912 NK6 transcription factor related, locus 2 [Homo sapi... 566 e-162
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap... 331 4e-91
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens] 96 4e-20
gi|116805350 homeo box (H6 family) 1 [Homo sapiens] 91 1e-18
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens] 82 4e-16
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens] 82 5e-16
gi|11386181 H2.0-like homeobox [Homo sapiens] 82 5e-16
gi|157743259 H6 family homeobox 3 [Homo sapiens] 82 7e-16
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 81 9e-16
gi|70608170 H6 family homeobox 2 [Homo sapiens] 80 1e-15
gi|89257348 homeo box HB9 [Homo sapiens] 80 1e-15
gi|118582284 msh homeobox 1 [Homo sapiens] 80 2e-15
gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens] 80 3e-15
gi|226437602 NK1 homeobox 2 [Homo sapiens] 78 7e-15
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens] 78 7e-15
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens] 78 7e-15
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens] 78 7e-15
gi|94536800 empty spiracles homolog 1 [Homo sapiens] 78 7e-15
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens] 78 1e-14
gi|4502365 NK3 homeobox 2 [Homo sapiens] 78 1e-14
gi|14149611 empty spiracles homeobox 2 [Homo sapiens] 76 3e-14
gi|4506049 hematopoietically expressed homeobox [Homo sapiens] 74 1e-13
gi|22749179 NK6 homeobox 3 [Homo sapiens] 74 1e-13
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 74 1e-13
gi|23397672 homeobox D4 [Homo sapiens] 72 5e-13
gi|24497538 homeobox C4 [Homo sapiens] 72 5e-13
gi|24497540 homeobox C4 [Homo sapiens] 72 5e-13
gi|153218470 BarH-like homeobox 1 [Homo sapiens] 72 5e-13
gi|4885185 distal-less homeobox 3 [Homo sapiens] 72 7e-13
gi|4758168 distal-less homeobox 2 [Homo sapiens] 72 7e-13
>gi|28912912 NK6 transcription factor related, locus 2 [Homo
sapiens]
Length = 277
Score = 567 bits (1460), Expect = e-162
Identities = 277/277 (100%), Positives = 277/277 (100%)
Query: 1 MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGI 60
MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGI
Sbjct: 1 MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGI 60
Query: 61 SDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPG 120
SDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPG
Sbjct: 61 SDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPG 120
Query: 121 VVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERAR 180
VVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERAR
Sbjct: 121 VVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERAR 180
Query: 181 LAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNR 240
LAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNR
Sbjct: 181 LAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNR 240
Query: 241 PLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDAL 277
PLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDAL
Sbjct: 241 PLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDAL 277
>gi|111120318 NK6 transcription factor related, locus 1 [Homo
sapiens]
Length = 367
Score = 331 bits (849), Expect = 4e-91
Identities = 189/356 (53%), Positives = 215/356 (60%), Gaps = 89/356 (25%)
Query: 1 MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYAL-------------------------- 34
M+ R AF+LSS PLAALH+MAEMKT L+P A
Sbjct: 7 MEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGT 66
Query: 35 QGPAGFKAPALGGLGA------QLPLGTPHGISDILGRP--------------------- 67
P G K PA GGL + QL TPHGI+DIL RP
Sbjct: 67 HNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSS 126
Query: 68 ----------------------VGAAGGGLLGGLPRLNGLASSA---GVYFGPAAAVARG 102
++ GLL GLPR + L+ G+YF P+AA
Sbjct: 127 SSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAA 186
Query: 103 ---YPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVL-DKDGKKKHSRPTFSGQ 158
YPKPLAELPGR PIFWPGV+Q PWRD RLA G +L DKDGK+KH+RPTFSGQ
Sbjct: 187 VGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQ 246
Query: 159 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQ 218
QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK+HAAEMA+AKKKQ
Sbjct: 247 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQ 306
Query: 219 DSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAG 274
DS+ E+LK + E+DD+YN+PLDPNSDDEKIT+LLKKHK S+ GGG G
Sbjct: 307 DSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSS-------GGGGG 355
>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
Length = 330
Score = 95.5 bits (236), Expect = 4e-20
Identities = 83/202 (41%), Positives = 102/202 (50%), Gaps = 20/202 (9%)
Query: 32 YALQGPAGFKAPALGGLGAQL-PLGTPHGISDIL-GRPVGAAGGGLLGGLPRLNGLASSA 89
Y GP G PA GG + PL + ++ L G P GGG GG G S+A
Sbjct: 74 YGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGA----GALSAA 129
Query: 90 GVYFGPA---AAVARGYPKPLAE-LPGRPPI-FWPGV--VQGA--PWRDP--RLAGPAPA 138
GV PA A A +P+PLA LP P + PGV + G PW + R
Sbjct: 130 GVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESNRRYTKDRFT 189
Query: 139 GGVLDK--DGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWF 196
G KKK R +F+ QI LEK F + KYLA ERA LA +L MT++QVK WF
Sbjct: 190 GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWF 249
Query: 197 QNRRTKWRKRHAAEMASAKKKQ 218
QNRRTKWR R AE A+++Q
Sbjct: 250 QNRRTKWR-RQTAEEREAERQQ 270
>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
Length = 348
Score = 90.9 bits (224), Expect = 1e-18
Identities = 68/186 (36%), Positives = 89/186 (47%), Gaps = 23/186 (12%)
Query: 31 PYALQ--GPAGFKAPALGGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGLASS 88
P+AL G A + A GG G L T S G +G A G G
Sbjct: 105 PFALGCGGAARWYPRAHGGYGGGLSPDTSDRDSPETGEEMGRAEGAWPRGP--------- 155
Query: 89 AGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDGKK 148
GP A + AEL R P G + + + A GGV G+K
Sbjct: 156 -----GPGAV-----QREAAELAARGPA--AGTEEASELAEVPAAAGETRGGVGVGGGRK 203
Query: 149 KHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHA 208
K +R FS Q+F LE TF+ +YL+ ERA LA SL +TE+QVK+WFQNRR KW+++ A
Sbjct: 204 KKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLA 263
Query: 209 AEMASA 214
AE+ +A
Sbjct: 264 AELEAA 269
>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
Length = 284
Score = 82.4 bits (202), Expect = 4e-16
Identities = 71/200 (35%), Positives = 93/200 (46%), Gaps = 34/200 (17%)
Query: 46 GGLGAQLPLGTPHGISDIL-GRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYP 104
GGLG G HG + G GA+G G G L L G S+GV GP +
Sbjct: 33 GGLGLGRG-GQGHGENGAFSGGYHGASGYGPAGSLAPLPG---SSGV--GPGGVIRVPAH 86
Query: 105 KPLAELP---GRPPIFWPGVVQGA--------PW--------RDPRLAGPAPAGGVLD-- 143
+PL P G P + P + GA PW +D A +P G
Sbjct: 87 RPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIG 146
Query: 144 ------KDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQ 197
K+K R +FS Q+ LE+ F + KYLA ERA LA +L MT++QVK WFQ
Sbjct: 147 HPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQ 206
Query: 198 NRRTKWRKRHAAEMASAKKK 217
NRRTKWR++ A E + + +
Sbjct: 207 NRRTKWRRQTAEEREAERHR 226
>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
Length = 411
Score = 82.0 bits (201), Expect = 5e-16
Identities = 61/165 (36%), Positives = 77/165 (46%), Gaps = 26/165 (15%)
Query: 65 GRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGY-PKPLAELPGRPPIFWPGVVQ 123
G GGG LG R +G +A P A V P P P V Q
Sbjct: 172 GAEEARGGGGGLGA--RGSGCQGAAETDASPGATVDEAAAPGPRENSP---------VAQ 220
Query: 124 GAPW--RDPRLAGPAPAG------------GVLDKDGKKKHSRPTFSGQQIFALEKTFEQ 169
G P P AG P G G K GK + +R F+ +Q+ ALE F+
Sbjct: 221 GPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKA 280
Query: 170 TKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASA 214
T+YL+ ER LA SL +TE+QVK+WFQNRRTKW+K++ SA
Sbjct: 281 TRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSA 325
>gi|11386181 H2.0-like homeobox [Homo sapiens]
Length = 488
Score = 82.0 bits (201), Expect = 5e-16
Identities = 66/178 (37%), Positives = 87/178 (48%), Gaps = 27/178 (15%)
Query: 75 LLGGLP---RLNGLASSAGVYFGPAAAV--ARGYPKPLAELPGRPPIFWPGVVQGAPWRD 129
L GG P L+GL SAG +F + A PL P + +
Sbjct: 203 LTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNP-----------RNSVQHQ 251
Query: 130 PRLAGPAPAGGVLDKDG-------KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLA 182
+ P P VL KD K+ SR FS Q LEK FE KY+ P+R +LA
Sbjct: 252 FQDTFPGPYA-VLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLA 310
Query: 183 YSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNR 240
LG+T++QVKVWFQNRR KW RH+ E A A+K +D +A + GG+ A D ++ R
Sbjct: 311 AMLGLTDAQVKVWFQNRRMKW--RHSKE-AQAQKDKDKEAGEKPSGGAPAADGEQDER 365
>gi|157743259 H6 family homeobox 3 [Homo sapiens]
Length = 357
Score = 81.6 bits (200), Expect = 7e-16
Identities = 37/68 (54%), Positives = 51/68 (75%)
Query: 147 KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKR 206
+KK +R FS Q+F LE TF+ +YL+ ERA LA SL +TE+QVK+WFQNRR KW+++
Sbjct: 226 RKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQ 285
Query: 207 HAAEMASA 214
AAE+ +A
Sbjct: 286 LAAELEAA 293
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 81.3 bits (199), Expect = 9e-16
Identities = 61/163 (37%), Positives = 77/163 (47%), Gaps = 22/163 (13%)
Query: 65 GRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGY-PKPLAELPGRPPIFWPGVVQ 123
G GGG LG R +G +A P A V P P P P G
Sbjct: 575 GAEEARGGGGGLGA--RGSGCQGAAETDASPGATVDEAAAPGPRENSPVAP-----GPPG 627
Query: 124 GAPWRDPRLAGPAPAG------------GVLDKDGKKKHSRPTFSGQQIFALEKTFEQTK 171
GA P AG P G G K GK + +R F+ +Q+ ALE F+ T+
Sbjct: 628 GAA--APGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATR 685
Query: 172 YLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASA 214
YL+ ER LA SL +TE+QVK+WFQNRRTKW+K++ SA
Sbjct: 686 YLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSA 728
>gi|70608170 H6 family homeobox 2 [Homo sapiens]
Length = 273
Score = 80.5 bits (197), Expect = 1e-15
Identities = 64/182 (35%), Positives = 84/182 (46%), Gaps = 31/182 (17%)
Query: 39 GFKAPAL-----GGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGLASSAGVYF 93
G+KAPA G Q P P LG P G+ G G GGL R L+ S +
Sbjct: 59 GWKAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGP-GGLERTPFLSPSHSDFK 117
Query: 94 GPAAAVA-RGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSR 152
+ G P P +E P RD G KK +R
Sbjct: 118 EEKERLLPAGSPSPGSERP----------------RD--------GGAERQAGAAKKKTR 153
Query: 153 PTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMA 212
FS Q++ LE TF+ +YL+ ERA LA SL +TE+QVK WFQNRR KW+++ +AE+
Sbjct: 154 TVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELE 213
Query: 213 SA 214
+A
Sbjct: 214 AA 215
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 80.5 bits (197), Expect = 1e-15
Identities = 73/216 (33%), Positives = 95/216 (43%), Gaps = 33/216 (15%)
Query: 33 ALQGPAGFKAPALGGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLN-GLASSAGV 91
A A A A GGL L P G G P AA L G P A++A
Sbjct: 122 AAAAAAAAAAAAAGGLALGLH---PGGAQGGAGLPAQAA----LYGHPVYGYSAAAAAAA 174
Query: 92 YFGPAAAVARGYPKPLAELPGRP--PI-FWPGVVQGAPWRDPRLAGPAPAGGVLDKD--- 145
G A++ YP+ P P PI G Q W + AG +L K
Sbjct: 175 LAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQW-----LRASTAGMILPKMPDF 229
Query: 146 ---------GKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWF 196
GK + R F+ QQ+ LE F+ KYL+ P+R +A SL +TE+QVK+WF
Sbjct: 230 NSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWF 289
Query: 197 QNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDA 232
QNRR KW++ AK++ +AEK K GG A
Sbjct: 290 QNRRMKWKR-----SKKAKEQAAQEAEKQKGGGGGA 320
>gi|118582284 msh homeobox 1 [Homo sapiens]
Length = 303
Score = 80.1 bits (196), Expect = 2e-15
Identities = 73/236 (30%), Positives = 106/236 (44%), Gaps = 42/236 (17%)
Query: 6 PGAFVLSSAPLAALHNMAEMKTS--LFPYALQG------PAGFKAPALGGLGAQLPLGTP 57
P A ++A + A A+ K S L P++++ G K AL G
Sbjct: 33 PSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQAAG-- 90
Query: 58 HGISDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIF 117
G + LG P G+ G PR G S G+ P A+ + AE P +P
Sbjct: 91 -GSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVK------AESPEKP--- 140
Query: 118 WPGVVQGAPW-RDPRLAGP-----APAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTK 171
+ PW + PR + P +P L K + R F+ Q+ ALE+ F Q +
Sbjct: 141 -----ERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQ 195
Query: 172 YLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKV 227
YL+ ERA + SL +TE+QVK+WFQNRR K AK+ Q+++ EKLK+
Sbjct: 196 YLSIAERAEFSSSLSLTETQVKIWFQNRRAK-----------AKRLQEAELEKLKM 240
>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
Length = 291
Score = 79.7 bits (195), Expect = 3e-15
Identities = 43/74 (58%), Positives = 51/74 (68%), Gaps = 1/74 (1%)
Query: 147 KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKR 206
K+K R +FS QI LEK F + KYLA ERA LA SL MT++QVK WFQNRRTKWR R
Sbjct: 165 KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWR-R 223
Query: 207 HAAEMASAKKKQDS 220
AE A+++Q S
Sbjct: 224 QTAEEREAERQQAS 237
>gi|226437602 NK1 homeobox 2 [Homo sapiens]
Length = 310
Score = 78.2 bits (191), Expect = 7e-15
Identities = 53/134 (39%), Positives = 71/134 (52%), Gaps = 14/134 (10%)
Query: 82 LNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGV 141
L GLA S PA A+A G P E G P+ P G+P R P A
Sbjct: 111 LPGLARSPDA---PAGALASGEP---CEDGGGGPVRSPPGSPGSPRPRRRRLEPNCA--- 161
Query: 142 LDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRT 201
K + +R F+ +Q+ ALE F T+YL+ ER LA SL +TE+QVK+WFQNRRT
Sbjct: 162 -----KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 216
Query: 202 KWRKRHAAEMASAK 215
KW+K++ +A+
Sbjct: 217 KWKKQNPGADGAAQ 230
>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 78.2 bits (191), Expect = 7e-15
Identities = 53/134 (39%), Positives = 71/134 (52%), Gaps = 14/134 (10%)
Query: 82 LNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGV 141
L GLA S PA A+A G P E G P+ P G+P R P A
Sbjct: 133 LPGLARSPDA---PAGALASGEP---CEDGGGGPVRSPPGSPGSPRPRRRRLEPNCA--- 183
Query: 142 LDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRT 201
K + +R F+ +Q+ ALE F T+YL+ ER LA SL +TE+QVK+WFQNRRT
Sbjct: 184 -----KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 238
Query: 202 KWRKRHAAEMASAK 215
KW+K++ +A+
Sbjct: 239 KWKKQNPGADGAAQ 252
>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 78.2 bits (191), Expect = 7e-15
Identities = 53/134 (39%), Positives = 71/134 (52%), Gaps = 14/134 (10%)
Query: 82 LNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGV 141
L GLA S PA A+A G P E G P+ P G+P R P A
Sbjct: 133 LPGLARSPDA---PAGALASGEP---CEDGGGGPVRSPPGSPGSPRPRRRRLEPNCA--- 183
Query: 142 LDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRT 201
K + +R F+ +Q+ ALE F T+YL+ ER LA SL +TE+QVK+WFQNRRT
Sbjct: 184 -----KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 238
Query: 202 KWRKRHAAEMASAK 215
KW+K++ +A+
Sbjct: 239 KWKKQNPGADGAAQ 252
>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 78.2 bits (191), Expect = 7e-15
Identities = 53/134 (39%), Positives = 71/134 (52%), Gaps = 14/134 (10%)
Query: 82 LNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGV 141
L GLA S PA A+A G P E G P+ P G+P R P A
Sbjct: 133 LPGLARSPDA---PAGALASGEP---CEDGGGGPVRSPPGSPGSPRPRRRRLEPNCA--- 183
Query: 142 LDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRT 201
K + +R F+ +Q+ ALE F T+YL+ ER LA SL +TE+QVK+WFQNRRT
Sbjct: 184 -----KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 238
Query: 202 KWRKRHAAEMASAK 215
KW+K++ +A+
Sbjct: 239 KWKKQNPGADGAAQ 252
>gi|94536800 empty spiracles homolog 1 [Homo sapiens]
Length = 290
Score = 78.2 bits (191), Expect = 7e-15
Identities = 78/277 (28%), Positives = 107/277 (38%), Gaps = 40/277 (14%)
Query: 6 PGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGISDILG 65
P A + +AP AA K +L G GG GA L + L
Sbjct: 20 PRARLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGGAGSHLLAAAASEEPL- 78
Query: 66 RPVG-------AAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPL-----AELPGR 113
RP AA + G P + +Y GP P A G
Sbjct: 79 RPTALNYPHPSAAEAAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGA 138
Query: 114 PPIFWPGVVQGAPWRDP----------RLAGPAPAGGVLDKDG---------KKKHSRPT 154
P+ P GA RDP R G + +DG K K R
Sbjct: 139 SPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTA 198
Query: 155 FSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAE---M 211
FS Q+ LE+ FE+ Y+ G ER +LA SL ++E+QVKVWFQNRRTK++++ E
Sbjct: 199 FSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPE 258
Query: 212 ASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDD 248
+ KKK + ++ A +D +D S+D
Sbjct: 259 SEQKKKGSHHINRWRIATKQANGED-----IDVTSND 290
>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 653
Score = 77.8 bits (190), Expect = 1e-14
Identities = 36/71 (50%), Positives = 50/71 (70%)
Query: 144 KDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKW 203
K GK + +R F+ +Q+ ALE F+ T+YL+ ER LA SL +TE+QVK+WFQNRRTKW
Sbjct: 93 KSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 152
Query: 204 RKRHAAEMASA 214
+K++ SA
Sbjct: 153 KKQNPGADTSA 163
>gi|4502365 NK3 homeobox 2 [Homo sapiens]
Length = 333
Score = 77.8 bits (190), Expect = 1e-14
Identities = 46/111 (41%), Positives = 65/111 (58%), Gaps = 9/111 (8%)
Query: 134 GPAPAGGVLDKDG------KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGM 187
G PAG +++ +KK SR FS Q+F LE+ F +YL+GPERA LA SL +
Sbjct: 186 GSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKL 245
Query: 188 TESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEY 238
TE+QVK+WFQNRR K ++R +MA+ A+K+ V +D +Y
Sbjct: 246 TETQVKIWFQNRRYKTKRR---QMAADLLASAPAAKKVAVKVLVRDDQRQY 293
>gi|14149611 empty spiracles homeobox 2 [Homo sapiens]
Length = 252
Score = 76.3 bits (186), Expect = 3e-14
Identities = 53/153 (34%), Positives = 76/153 (49%), Gaps = 13/153 (8%)
Query: 104 PKPLAELPGRPP-IFWPGVVQGAPWRDPRLAG--PAPAGGVLDKD--GKKKHSRPTFSGQ 158
P PL R P F+P ++ + R G +P +L K K R FS
Sbjct: 105 PHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPS 164
Query: 159 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMAS---AK 215
Q+ LE FE+ Y+ G ER +LA+SL +TE+QVKVWFQNRRTK++++ E S K
Sbjct: 165 QLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQK 224
Query: 216 KKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDD 248
KK + ++ A ++ +D SDD
Sbjct: 225 KKGTHHINRWRIATKQASPEE-----IDVTSDD 252
>gi|4506049 hematopoietically expressed homeobox [Homo sapiens]
Length = 270
Score = 74.3 bits (181), Expect = 1e-13
Identities = 71/206 (34%), Positives = 87/206 (42%), Gaps = 36/206 (17%)
Query: 43 PALGGLGAQL----PL-----GTPHGISDILGRPVGAAGGGLLGGLPRLNG-LASSAGVY 92
PA G +G L PL TP I DILGR G A LP N S Y
Sbjct: 8 PAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGR--GPAAPTPAPTLPSPNSSFTSLVSPY 65
Query: 93 FGP---------------AAAVAR-----GYPKPLAELPGRPPIFWPGVVQGAPWRDPRL 132
P AAA+A G+ PL P + +++ P P L
Sbjct: 66 RTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLL 125
Query: 133 AGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQV 192
P + K+K + FS Q LEK FE KYL+ PER RLA L ++E QV
Sbjct: 126 WSPFLQRPL----HKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQV 181
Query: 193 KVWFQNRRTKWRKRHAAEMASAKKKQ 218
K WFQNRR KWR+ S KK++
Sbjct: 182 KTWFQNRRAKWRRLKQENPQSNKKEE 207
>gi|22749179 NK6 homeobox 3 [Homo sapiens]
Length = 135
Score = 74.3 bits (181), Expect = 1e-13
Identities = 38/69 (55%), Positives = 47/69 (68%), Gaps = 4/69 (5%)
Query: 194 VWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDA---EDDDEYNRPLDPNSDDEK 250
VWFQNRRTKWRK+ A E +S+ + A GG A +DDEYN+PLDP+SDDEK
Sbjct: 55 VWFQNRRTKWRKKSALEPSSSTPRAPGGAGA-GAGGDRAPSENEDDEYNKPLDPDSDDEK 113
Query: 251 ITRLLKKHK 259
I LL+KH+
Sbjct: 114 IRLLLRKHR 122
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 73.9 bits (180), Expect = 1e-13
Identities = 49/129 (37%), Positives = 69/129 (53%), Gaps = 21/129 (16%)
Query: 85 LASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDK 144
L SSAG GP A + PKP +L G G +GAP GV
Sbjct: 219 LDSSAG---GPGALLG---PKP--KLKGS---LGTGAEEGAP----------VTAGVTAP 257
Query: 145 DGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWR 204
GK + R F+ +Q+ LEK F KYL+ ER+++A++L ++E QVK+WFQNRR KW+
Sbjct: 258 GGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWK 317
Query: 205 KRHAAEMAS 213
+ A ++S
Sbjct: 318 RIKAGNVSS 326
>gi|23397672 homeobox D4 [Homo sapiens]
Length = 255
Score = 72.0 bits (175), Expect = 5e-13
Identities = 64/211 (30%), Positives = 85/211 (40%), Gaps = 25/211 (11%)
Query: 32 YALQGPAGFKAPALGGLGAQLPLGTPHGI---SDILGRPVGAAGGGLLGGLPRLNGLASS 88
Y G G + G GAQ P G+ D +P G +G G LP G
Sbjct: 23 YLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPA-RGHGQE 81
Query: 89 AGVYFGPAAAVARGYPKPLAELPGRPPIFWPGV---VQGAPWRDPR---LAGPAPAGGVL 142
G G AA P P P PP PG Q P + P L PA +
Sbjct: 82 PGGPGGHYAAPGEPCPAP----PAPPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWM 137
Query: 143 DK-----------DGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQ 191
K G+ K SR ++ QQ+ LEK F +YL R +A++L ++E Q
Sbjct: 138 KKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQ 197
Query: 192 VKVWFQNRRTKWRKRHAAEMASAKKKQDSDA 222
+K+WFQNRR KW+K H + S +
Sbjct: 198 IKIWFQNRRMKWKKDHKLPNTKGRSSSSSSS 228
>gi|24497538 homeobox C4 [Homo sapiens]
Length = 264
Score = 72.0 bits (175), Expect = 5e-13
Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 146 GKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 205
G+ K SR ++ QQ+ LEK F +YL R +A+SL ++E Q+K+WFQNRR KW+K
Sbjct: 154 GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213
Query: 206 RHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDD--EKITRL 254
H + + A + + +++++ P E ITRL
Sbjct: 214 DHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 264
>gi|24497540 homeobox C4 [Homo sapiens]
Length = 264
Score = 72.0 bits (175), Expect = 5e-13
Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 146 GKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 205
G+ K SR ++ QQ+ LEK F +YL R +A+SL ++E Q+K+WFQNRR KW+K
Sbjct: 154 GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213
Query: 206 RHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDD--EKITRL 254
H + + A + + +++++ P E ITRL
Sbjct: 214 DHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 264
>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
Length = 254
Score = 72.0 bits (175), Expect = 5e-13
Identities = 47/119 (39%), Positives = 60/119 (50%), Gaps = 17/119 (14%)
Query: 87 SSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDG 146
SSA + GP A G P EL R + AGP G K
Sbjct: 98 SSALLAAGPGLPGAAGAPHLPLELQLRGKL--------------EAAGPGEPG---TKAK 140
Query: 147 KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 205
K + SR F+ Q+ LEK FE+ KYL+ P+R LA SLG+++ QVK W+QNRR KW+K
Sbjct: 141 KGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 199
>gi|4885185 distal-less homeobox 3 [Homo sapiens]
Length = 287
Score = 71.6 bits (174), Expect = 7e-13
Identities = 38/86 (44%), Positives = 54/86 (62%), Gaps = 3/86 (3%)
Query: 123 QGAPWRDPRLAGPAPAGGVLDKDGKKKH---SRPTFSGQQIFALEKTFEQTKYLAGPERA 179
Q P +DP P V +GK K R +S Q+ AL++ F++ +YLA PERA
Sbjct: 101 QPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERA 160
Query: 180 RLAYSLGMTESQVKVWFQNRRTKWRK 205
LA LG+T++QVK+WFQNRR+K++K
Sbjct: 161 ELAAQLGLTQTQVKIWFQNRRSKFKK 186
>gi|4758168 distal-less homeobox 2 [Homo sapiens]
Length = 328
Score = 71.6 bits (174), Expect = 7e-13
Identities = 33/62 (53%), Positives = 48/62 (77%)
Query: 144 KDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKW 203
K K + R +S Q+ AL++ F++T+YLA PERA LA SLG+T++QVK+WFQNRR+K+
Sbjct: 148 KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKF 207
Query: 204 RK 205
+K
Sbjct: 208 KK 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,718,985
Number of Sequences: 37866
Number of extensions: 726225
Number of successful extensions: 2738
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 287
Number of HSP's successfully gapped in prelim test: 115
Number of HSP's that attempted gapping in prelim test: 2205
Number of HSP's gapped (non-prelim): 624
length of query: 277
length of database: 18,247,518
effective HSP length: 101
effective length of query: 176
effective length of database: 14,423,052
effective search space: 2538457152
effective search space used: 2538457152
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.