Guide to the Human Genome
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Search of human proteins with 28912912

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28912912 NK6 transcription factor related, locus 2 [Homo
sapiens]
         (277 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28912912 NK6 transcription factor related, locus 2 [Homo sapi...   566   e-162
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...   331   4e-91
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]                   96   4e-20
gi|116805350 homeo box (H6 family) 1 [Homo sapiens]                    91   1e-18
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]                   82   4e-16
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]                82   5e-16
gi|11386181 H2.0-like homeobox [Homo sapiens]                          82   5e-16
gi|157743259 H6 family homeobox 3 [Homo sapiens]                       82   7e-16
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  81   9e-16
gi|70608170 H6 family homeobox 2 [Homo sapiens]                        80   1e-15
gi|89257348 homeo box HB9 [Homo sapiens]                               80   1e-15
gi|118582284 msh homeobox 1 [Homo sapiens]                             80   2e-15
gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]                  80   3e-15
gi|226437602 NK1 homeobox 2 [Homo sapiens]                             78   7e-15
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  78   7e-15
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  78   7e-15
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  78   7e-15
gi|94536800 empty spiracles homolog 1 [Homo sapiens]                   78   7e-15
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  78   1e-14
gi|4502365 NK3 homeobox 2 [Homo sapiens]                               78   1e-14
gi|14149611 empty spiracles homeobox 2 [Homo sapiens]                  76   3e-14
gi|4506049 hematopoietically expressed homeobox [Homo sapiens]         74   1e-13
gi|22749179 NK6 homeobox 3 [Homo sapiens]                              74   1e-13
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]             74   1e-13
gi|23397672 homeobox D4 [Homo sapiens]                                 72   5e-13
gi|24497538 homeobox C4 [Homo sapiens]                                 72   5e-13
gi|24497540 homeobox C4 [Homo sapiens]                                 72   5e-13
gi|153218470 BarH-like homeobox 1 [Homo sapiens]                       72   5e-13
gi|4885185 distal-less homeobox 3 [Homo sapiens]                       72   7e-13
gi|4758168 distal-less homeobox 2 [Homo sapiens]                       72   7e-13

>gi|28912912 NK6 transcription factor related, locus 2 [Homo
           sapiens]
          Length = 277

 Score =  567 bits (1460), Expect = e-162
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGI 60
           MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGI
Sbjct: 1   MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGI 60

Query: 61  SDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPG 120
           SDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPG
Sbjct: 61  SDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPG 120

Query: 121 VVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERAR 180
           VVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERAR
Sbjct: 121 VVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERAR 180

Query: 181 LAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNR 240
           LAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNR
Sbjct: 181 LAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNR 240

Query: 241 PLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDAL 277
           PLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDAL
Sbjct: 241 PLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDAL 277


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score =  331 bits (849), Expect = 4e-91
 Identities = 189/356 (53%), Positives = 215/356 (60%), Gaps = 89/356 (25%)

Query: 1   MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYAL-------------------------- 34
           M+  R  AF+LSS PLAALH+MAEMKT L+P A                           
Sbjct: 7   MEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGT 66

Query: 35  QGPAGFKAPALGGLGA------QLPLGTPHGISDILGRP--------------------- 67
             P G K PA GGL +      QL   TPHGI+DIL RP                     
Sbjct: 67  HNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSS 126

Query: 68  ----------------------VGAAGGGLLGGLPRLNGLASSA---GVYFGPAAAVARG 102
                                   ++  GLL GLPR + L+      G+YF P+AA    
Sbjct: 127 SSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAA 186

Query: 103 ---YPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVL-DKDGKKKHSRPTFSGQ 158
              YPKPLAELPGR PIFWPGV+Q  PWRD RLA     G +L DKDGK+KH+RPTFSGQ
Sbjct: 187 VGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQ 246

Query: 159 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQ 218
           QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK+HAAEMA+AKKKQ
Sbjct: 247 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQ 306

Query: 219 DSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAG 274
           DS+ E+LK    + E+DD+YN+PLDPNSDDEKIT+LLKKHK S+       GGG G
Sbjct: 307 DSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSS-------GGGGG 355


>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
          Length = 330

 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 83/202 (41%), Positives = 102/202 (50%), Gaps = 20/202 (9%)

Query: 32  YALQGPAGFKAPALGGLGAQL-PLGTPHGISDIL-GRPVGAAGGGLLGGLPRLNGLASSA 89
           Y   GP G   PA GG    + PL   + ++  L G P    GGG  GG     G  S+A
Sbjct: 74  YGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGA----GALSAA 129

Query: 90  GVYFGPA---AAVARGYPKPLAE-LPGRPPI-FWPGV--VQGA--PWRDP--RLAGPAPA 138
           GV   PA    A A  +P+PLA  LP  P +   PGV  + G   PW +   R       
Sbjct: 130 GVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESNRRYTKDRFT 189

Query: 139 GGVLDK--DGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWF 196
           G         KKK  R +F+  QI  LEK F + KYLA  ERA LA +L MT++QVK WF
Sbjct: 190 GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWF 249

Query: 197 QNRRTKWRKRHAAEMASAKKKQ 218
           QNRRTKWR R  AE   A+++Q
Sbjct: 250 QNRRTKWR-RQTAEEREAERQQ 270


>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
          Length = 348

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 68/186 (36%), Positives = 89/186 (47%), Gaps = 23/186 (12%)

Query: 31  PYALQ--GPAGFKAPALGGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGLASS 88
           P+AL   G A +   A GG G  L   T    S   G  +G A G    G          
Sbjct: 105 PFALGCGGAARWYPRAHGGYGGGLSPDTSDRDSPETGEEMGRAEGAWPRGP--------- 155

Query: 89  AGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDGKK 148
                GP A       +  AEL  R P    G  + +   +   A     GGV    G+K
Sbjct: 156 -----GPGAV-----QREAAELAARGPA--AGTEEASELAEVPAAAGETRGGVGVGGGRK 203

Query: 149 KHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHA 208
           K +R  FS  Q+F LE TF+  +YL+  ERA LA SL +TE+QVK+WFQNRR KW+++ A
Sbjct: 204 KKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLA 263

Query: 209 AEMASA 214
           AE+ +A
Sbjct: 264 AELEAA 269


>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
          Length = 284

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 71/200 (35%), Positives = 93/200 (46%), Gaps = 34/200 (17%)

Query: 46  GGLGAQLPLGTPHGISDIL-GRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYP 104
           GGLG     G  HG +    G   GA+G G  G L  L G   S+GV  GP   +     
Sbjct: 33  GGLGLGRG-GQGHGENGAFSGGYHGASGYGPAGSLAPLPG---SSGV--GPGGVIRVPAH 86

Query: 105 KPLAELP---GRPPIFWPGVVQGA--------PW--------RDPRLAGPAPAGGVLD-- 143
           +PL   P   G P +  P  + GA        PW        +D   A  +P  G     
Sbjct: 87  RPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIG 146

Query: 144 ------KDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQ 197
                    K+K  R +FS  Q+  LE+ F + KYLA  ERA LA +L MT++QVK WFQ
Sbjct: 147 HPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQ 206

Query: 198 NRRTKWRKRHAAEMASAKKK 217
           NRRTKWR++ A E  + + +
Sbjct: 207 NRRTKWRRQTAEEREAERHR 226


>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
          Length = 411

 Score = 82.0 bits (201), Expect = 5e-16
 Identities = 61/165 (36%), Positives = 77/165 (46%), Gaps = 26/165 (15%)

Query: 65  GRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGY-PKPLAELPGRPPIFWPGVVQ 123
           G      GGG LG   R +G   +A     P A V     P P    P         V Q
Sbjct: 172 GAEEARGGGGGLGA--RGSGCQGAAETDASPGATVDEAAAPGPRENSP---------VAQ 220

Query: 124 GAPW--RDPRLAGPAPAG------------GVLDKDGKKKHSRPTFSGQQIFALEKTFEQ 169
           G P     P  AG  P G            G   K GK + +R  F+ +Q+ ALE  F+ 
Sbjct: 221 GPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKA 280

Query: 170 TKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASA 214
           T+YL+  ER  LA SL +TE+QVK+WFQNRRTKW+K++     SA
Sbjct: 281 TRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSA 325


>gi|11386181 H2.0-like homeobox [Homo sapiens]
          Length = 488

 Score = 82.0 bits (201), Expect = 5e-16
 Identities = 66/178 (37%), Positives = 87/178 (48%), Gaps = 27/178 (15%)

Query: 75  LLGGLP---RLNGLASSAGVYFGPAAAV--ARGYPKPLAELPGRPPIFWPGVVQGAPWRD 129
           L GG P    L+GL  SAG +F     +  A     PL   P           + +    
Sbjct: 203 LTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNP-----------RNSVQHQ 251

Query: 130 PRLAGPAPAGGVLDKDG-------KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLA 182
            +   P P   VL KD        K+  SR  FS  Q   LEK FE  KY+  P+R +LA
Sbjct: 252 FQDTFPGPYA-VLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLA 310

Query: 183 YSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNR 240
             LG+T++QVKVWFQNRR KW  RH+ E A A+K +D +A +   GG+ A D ++  R
Sbjct: 311 AMLGLTDAQVKVWFQNRRMKW--RHSKE-AQAQKDKDKEAGEKPSGGAPAADGEQDER 365


>gi|157743259 H6 family homeobox 3 [Homo sapiens]
          Length = 357

 Score = 81.6 bits (200), Expect = 7e-16
 Identities = 37/68 (54%), Positives = 51/68 (75%)

Query: 147 KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKR 206
           +KK +R  FS  Q+F LE TF+  +YL+  ERA LA SL +TE+QVK+WFQNRR KW+++
Sbjct: 226 RKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQ 285

Query: 207 HAAEMASA 214
            AAE+ +A
Sbjct: 286 LAAELEAA 293


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 81.3 bits (199), Expect = 9e-16
 Identities = 61/163 (37%), Positives = 77/163 (47%), Gaps = 22/163 (13%)

Query: 65  GRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGY-PKPLAELPGRPPIFWPGVVQ 123
           G      GGG LG   R +G   +A     P A V     P P    P  P     G   
Sbjct: 575 GAEEARGGGGGLGA--RGSGCQGAAETDASPGATVDEAAAPGPRENSPVAP-----GPPG 627

Query: 124 GAPWRDPRLAGPAPAG------------GVLDKDGKKKHSRPTFSGQQIFALEKTFEQTK 171
           GA    P  AG  P G            G   K GK + +R  F+ +Q+ ALE  F+ T+
Sbjct: 628 GAA--APGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATR 685

Query: 172 YLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASA 214
           YL+  ER  LA SL +TE+QVK+WFQNRRTKW+K++     SA
Sbjct: 686 YLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSA 728


>gi|70608170 H6 family homeobox 2 [Homo sapiens]
          Length = 273

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 64/182 (35%), Positives = 84/182 (46%), Gaps = 31/182 (17%)

Query: 39  GFKAPAL-----GGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGLASSAGVYF 93
           G+KAPA       G   Q P   P      LG P G+ G G  GGL R   L+ S   + 
Sbjct: 59  GWKAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGP-GGLERTPFLSPSHSDFK 117

Query: 94  GPAAAVA-RGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSR 152
                +   G P P +E P                RD         G        KK +R
Sbjct: 118 EEKERLLPAGSPSPGSERP----------------RD--------GGAERQAGAAKKKTR 153

Query: 153 PTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMA 212
             FS  Q++ LE TF+  +YL+  ERA LA SL +TE+QVK WFQNRR KW+++ +AE+ 
Sbjct: 154 TVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELE 213

Query: 213 SA 214
           +A
Sbjct: 214 AA 215


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 73/216 (33%), Positives = 95/216 (43%), Gaps = 33/216 (15%)

Query: 33  ALQGPAGFKAPALGGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLN-GLASSAGV 91
           A    A   A A GGL   L    P G     G P  AA    L G P      A++A  
Sbjct: 122 AAAAAAAAAAAAAGGLALGLH---PGGAQGGAGLPAQAA----LYGHPVYGYSAAAAAAA 174

Query: 92  YFGPAAAVARGYPKPLAELPGRP--PI-FWPGVVQGAPWRDPRLAGPAPAGGVLDKD--- 145
             G   A++  YP+     P  P  PI    G  Q   W        + AG +L K    
Sbjct: 175 LAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQW-----LRASTAGMILPKMPDF 229

Query: 146 ---------GKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWF 196
                    GK +  R  F+ QQ+  LE  F+  KYL+ P+R  +A SL +TE+QVK+WF
Sbjct: 230 NSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWF 289

Query: 197 QNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDA 232
           QNRR KW++        AK++   +AEK K GG  A
Sbjct: 290 QNRRMKWKR-----SKKAKEQAAQEAEKQKGGGGGA 320


>gi|118582284 msh homeobox 1 [Homo sapiens]
          Length = 303

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 73/236 (30%), Positives = 106/236 (44%), Gaps = 42/236 (17%)

Query: 6   PGAFVLSSAPLAALHNMAEMKTS--LFPYALQG------PAGFKAPALGGLGAQLPLGTP 57
           P A   ++A + A    A+ K S  L P++++         G K  AL         G  
Sbjct: 33  PSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQAAG-- 90

Query: 58  HGISDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIF 117
            G +  LG P G+ G       PR  G  S  G+   P  A+ +      AE P +P   
Sbjct: 91  -GSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVK------AESPEKP--- 140

Query: 118 WPGVVQGAPW-RDPRLAGP-----APAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTK 171
                +  PW + PR + P     +P    L K    +  R  F+  Q+ ALE+ F Q +
Sbjct: 141 -----ERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQ 195

Query: 172 YLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKV 227
           YL+  ERA  + SL +TE+QVK+WFQNRR K           AK+ Q+++ EKLK+
Sbjct: 196 YLSIAERAEFSSSLSLTETQVKIWFQNRRAK-----------AKRLQEAELEKLKM 240


>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
          Length = 291

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 43/74 (58%), Positives = 51/74 (68%), Gaps = 1/74 (1%)

Query: 147 KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKR 206
           K+K  R +FS  QI  LEK F + KYLA  ERA LA SL MT++QVK WFQNRRTKWR R
Sbjct: 165 KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWR-R 223

Query: 207 HAAEMASAKKKQDS 220
             AE   A+++Q S
Sbjct: 224 QTAEEREAERQQAS 237


>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 53/134 (39%), Positives = 71/134 (52%), Gaps = 14/134 (10%)

Query: 82  LNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGV 141
           L GLA S      PA A+A G P    E  G  P+  P    G+P    R   P  A   
Sbjct: 111 LPGLARSPDA---PAGALASGEP---CEDGGGGPVRSPPGSPGSPRPRRRRLEPNCA--- 161

Query: 142 LDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRT 201
                K + +R  F+ +Q+ ALE  F  T+YL+  ER  LA SL +TE+QVK+WFQNRRT
Sbjct: 162 -----KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 216

Query: 202 KWRKRHAAEMASAK 215
           KW+K++     +A+
Sbjct: 217 KWKKQNPGADGAAQ 230


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 53/134 (39%), Positives = 71/134 (52%), Gaps = 14/134 (10%)

Query: 82  LNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGV 141
           L GLA S      PA A+A G P    E  G  P+  P    G+P    R   P  A   
Sbjct: 133 LPGLARSPDA---PAGALASGEP---CEDGGGGPVRSPPGSPGSPRPRRRRLEPNCA--- 183

Query: 142 LDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRT 201
                K + +R  F+ +Q+ ALE  F  T+YL+  ER  LA SL +TE+QVK+WFQNRRT
Sbjct: 184 -----KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 238

Query: 202 KWRKRHAAEMASAK 215
           KW+K++     +A+
Sbjct: 239 KWKKQNPGADGAAQ 252


>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 53/134 (39%), Positives = 71/134 (52%), Gaps = 14/134 (10%)

Query: 82  LNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGV 141
           L GLA S      PA A+A G P    E  G  P+  P    G+P    R   P  A   
Sbjct: 133 LPGLARSPDA---PAGALASGEP---CEDGGGGPVRSPPGSPGSPRPRRRRLEPNCA--- 183

Query: 142 LDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRT 201
                K + +R  F+ +Q+ ALE  F  T+YL+  ER  LA SL +TE+QVK+WFQNRRT
Sbjct: 184 -----KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 238

Query: 202 KWRKRHAAEMASAK 215
           KW+K++     +A+
Sbjct: 239 KWKKQNPGADGAAQ 252


>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 53/134 (39%), Positives = 71/134 (52%), Gaps = 14/134 (10%)

Query: 82  LNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGV 141
           L GLA S      PA A+A G P    E  G  P+  P    G+P    R   P  A   
Sbjct: 133 LPGLARSPDA---PAGALASGEP---CEDGGGGPVRSPPGSPGSPRPRRRRLEPNCA--- 183

Query: 142 LDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRT 201
                K + +R  F+ +Q+ ALE  F  T+YL+  ER  LA SL +TE+QVK+WFQNRRT
Sbjct: 184 -----KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRT 238

Query: 202 KWRKRHAAEMASAK 215
           KW+K++     +A+
Sbjct: 239 KWKKQNPGADGAAQ 252


>gi|94536800 empty spiracles homolog 1 [Homo sapiens]
          Length = 290

 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 78/277 (28%), Positives = 107/277 (38%), Gaps = 40/277 (14%)

Query: 6   PGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGISDILG 65
           P A +  +AP AA       K      +L    G      GG GA   L       + L 
Sbjct: 20  PRARLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGGAGSHLLAAAASEEPL- 78

Query: 66  RPVG-------AAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPL-----AELPGR 113
           RP         AA    + G P      +   +Y GP          P      A   G 
Sbjct: 79  RPTALNYPHPSAAEAAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGA 138

Query: 114 PPIFWPGVVQGAPWRDP----------RLAGPAPAGGVLDKDG---------KKKHSRPT 154
            P+  P    GA  RDP          R  G       + +DG         K K  R  
Sbjct: 139 SPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTA 198

Query: 155 FSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAE---M 211
           FS  Q+  LE+ FE+  Y+ G ER +LA SL ++E+QVKVWFQNRRTK++++   E    
Sbjct: 199 FSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPE 258

Query: 212 ASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDD 248
           +  KKK      + ++    A  +D     +D  S+D
Sbjct: 259 SEQKKKGSHHINRWRIATKQANGED-----IDVTSND 290


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 36/71 (50%), Positives = 50/71 (70%)

Query: 144 KDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKW 203
           K GK + +R  F+ +Q+ ALE  F+ T+YL+  ER  LA SL +TE+QVK+WFQNRRTKW
Sbjct: 93  KSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 152

Query: 204 RKRHAAEMASA 214
           +K++     SA
Sbjct: 153 KKQNPGADTSA 163


>gi|4502365 NK3 homeobox 2 [Homo sapiens]
          Length = 333

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 46/111 (41%), Positives = 65/111 (58%), Gaps = 9/111 (8%)

Query: 134 GPAPAGGVLDKDG------KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGM 187
           G  PAG   +++       +KK SR  FS  Q+F LE+ F   +YL+GPERA LA SL +
Sbjct: 186 GSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKL 245

Query: 188 TESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEY 238
           TE+QVK+WFQNRR K ++R   +MA+        A+K+ V     +D  +Y
Sbjct: 246 TETQVKIWFQNRRYKTKRR---QMAADLLASAPAAKKVAVKVLVRDDQRQY 293


>gi|14149611 empty spiracles homeobox 2 [Homo sapiens]
          Length = 252

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 53/153 (34%), Positives = 76/153 (49%), Gaps = 13/153 (8%)

Query: 104 PKPLAELPGRPP-IFWPGVVQGAPWRDPRLAG--PAPAGGVLDKD--GKKKHSRPTFSGQ 158
           P PL     R P  F+P ++    +   R  G   +P   +L      K K  R  FS  
Sbjct: 105 PHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPS 164

Query: 159 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMAS---AK 215
           Q+  LE  FE+  Y+ G ER +LA+SL +TE+QVKVWFQNRRTK++++   E  S    K
Sbjct: 165 QLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQK 224

Query: 216 KKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDD 248
           KK      + ++    A  ++     +D  SDD
Sbjct: 225 KKGTHHINRWRIATKQASPEE-----IDVTSDD 252


>gi|4506049 hematopoietically expressed homeobox [Homo sapiens]
          Length = 270

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 71/206 (34%), Positives = 87/206 (42%), Gaps = 36/206 (17%)

Query: 43  PALGGLGAQL----PL-----GTPHGISDILGRPVGAAGGGLLGGLPRLNG-LASSAGVY 92
           PA G +G  L    PL      TP  I DILGR  G A       LP  N    S    Y
Sbjct: 8   PAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGR--GPAAPTPAPTLPSPNSSFTSLVSPY 65

Query: 93  FGP---------------AAAVAR-----GYPKPLAELPGRPPIFWPGVVQGAPWRDPRL 132
             P               AAA+A      G+  PL   P     +   +++  P   P L
Sbjct: 66  RTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLL 125

Query: 133 AGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQV 192
             P     +     K+K  +  FS  Q   LEK FE  KYL+ PER RLA  L ++E QV
Sbjct: 126 WSPFLQRPL----HKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQV 181

Query: 193 KVWFQNRRTKWRKRHAAEMASAKKKQ 218
           K WFQNRR KWR+       S KK++
Sbjct: 182 KTWFQNRRAKWRRLKQENPQSNKKEE 207


>gi|22749179 NK6 homeobox 3 [Homo sapiens]
          Length = 135

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 38/69 (55%), Positives = 47/69 (68%), Gaps = 4/69 (5%)

Query: 194 VWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDA---EDDDEYNRPLDPNSDDEK 250
           VWFQNRRTKWRK+ A E +S+  +    A     GG  A    +DDEYN+PLDP+SDDEK
Sbjct: 55  VWFQNRRTKWRKKSALEPSSSTPRAPGGAGA-GAGGDRAPSENEDDEYNKPLDPDSDDEK 113

Query: 251 ITRLLKKHK 259
           I  LL+KH+
Sbjct: 114 IRLLLRKHR 122


>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
          Length = 363

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 49/129 (37%), Positives = 69/129 (53%), Gaps = 21/129 (16%)

Query: 85  LASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDK 144
           L SSAG   GP A +    PKP  +L G       G  +GAP             GV   
Sbjct: 219 LDSSAG---GPGALLG---PKP--KLKGS---LGTGAEEGAP----------VTAGVTAP 257

Query: 145 DGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWR 204
            GK +  R  F+ +Q+  LEK F   KYL+  ER+++A++L ++E QVK+WFQNRR KW+
Sbjct: 258 GGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWK 317

Query: 205 KRHAAEMAS 213
           +  A  ++S
Sbjct: 318 RIKAGNVSS 326


>gi|23397672 homeobox D4 [Homo sapiens]
          Length = 255

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 64/211 (30%), Positives = 85/211 (40%), Gaps = 25/211 (11%)

Query: 32  YALQGPAGFKAPALGGLGAQLPLGTPHGI---SDILGRPVGAAGGGLLGGLPRLNGLASS 88
           Y   G  G +     G GAQ     P G+    D   +P G +G G    LP   G    
Sbjct: 23  YLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPA-RGHGQE 81

Query: 89  AGVYFGPAAAVARGYPKPLAELPGRPPIFWPGV---VQGAPWRDPR---LAGPAPAGGVL 142
            G   G  AA     P P    P  PP   PG     Q  P + P    L  PA     +
Sbjct: 82  PGGPGGHYAAPGEPCPAP----PAPPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWM 137

Query: 143 DK-----------DGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQ 191
            K            G+ K SR  ++ QQ+  LEK F   +YL    R  +A++L ++E Q
Sbjct: 138 KKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQ 197

Query: 192 VKVWFQNRRTKWRKRHAAEMASAKKKQDSDA 222
           +K+WFQNRR KW+K H       +    S +
Sbjct: 198 IKIWFQNRRMKWKKDHKLPNTKGRSSSSSSS 228


>gi|24497538 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 2/111 (1%)

Query: 146 GKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 205
           G+ K SR  ++ QQ+  LEK F   +YL    R  +A+SL ++E Q+K+WFQNRR KW+K
Sbjct: 154 GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213

Query: 206 RHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDD--EKITRL 254
            H       +    + A    +  +     +++++   P      E ITRL
Sbjct: 214 DHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 264


>gi|24497540 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 2/111 (1%)

Query: 146 GKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 205
           G+ K SR  ++ QQ+  LEK F   +YL    R  +A+SL ++E Q+K+WFQNRR KW+K
Sbjct: 154 GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213

Query: 206 RHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDD--EKITRL 254
            H       +    + A    +  +     +++++   P      E ITRL
Sbjct: 214 DHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 264


>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
          Length = 254

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 47/119 (39%), Positives = 60/119 (50%), Gaps = 17/119 (14%)

Query: 87  SSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDG 146
           SSA +  GP    A G P    EL  R  +                AGP   G    K  
Sbjct: 98  SSALLAAGPGLPGAAGAPHLPLELQLRGKL--------------EAAGPGEPG---TKAK 140

Query: 147 KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 205
           K + SR  F+  Q+  LEK FE+ KYL+ P+R  LA SLG+++ QVK W+QNRR KW+K
Sbjct: 141 KGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 199


>gi|4885185 distal-less homeobox 3 [Homo sapiens]
          Length = 287

 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 38/86 (44%), Positives = 54/86 (62%), Gaps = 3/86 (3%)

Query: 123 QGAPWRDPRLAGPAPAGGVLDKDGKKKH---SRPTFSGQQIFALEKTFEQTKYLAGPERA 179
           Q  P +DP      P   V   +GK K     R  +S  Q+ AL++ F++ +YLA PERA
Sbjct: 101 QPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERA 160

Query: 180 RLAYSLGMTESQVKVWFQNRRTKWRK 205
            LA  LG+T++QVK+WFQNRR+K++K
Sbjct: 161 ELAAQLGLTQTQVKIWFQNRRSKFKK 186


>gi|4758168 distal-less homeobox 2 [Homo sapiens]
          Length = 328

 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 33/62 (53%), Positives = 48/62 (77%)

Query: 144 KDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKW 203
           K  K +  R  +S  Q+ AL++ F++T+YLA PERA LA SLG+T++QVK+WFQNRR+K+
Sbjct: 148 KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKF 207

Query: 204 RK 205
           +K
Sbjct: 208 KK 209


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.135    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,718,985
Number of Sequences: 37866
Number of extensions: 726225
Number of successful extensions: 2738
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 287
Number of HSP's successfully gapped in prelim test: 115
Number of HSP's that attempted gapping in prelim test: 2205
Number of HSP's gapped (non-prelim): 624
length of query: 277
length of database: 18,247,518
effective HSP length: 101
effective length of query: 176
effective length of database: 14,423,052
effective search space: 2538457152
effective search space used: 2538457152
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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