Guide to the Human Genome
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Search of human proteins with 28872794

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28872794 CCAAT/enhancer binding protein alpha [Homo sapiens]
         (358 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28872794 CCAAT/enhancer binding protein alpha [Homo sapiens]       749   0.0  
gi|28872800 CCAAT/enhancer binding protein epsilon [Homo sapiens]     167   1e-41
gi|28872796 CCAAT/enhancer binding protein beta [Homo sapiens]        153   3e-37
gi|28872798 CCAAT/enhancer binding protein delta [Homo sapiens]       119   5e-27
gi|4502769 CCAAT/enhancer binding protein gamma [Homo sapiens]         77   3e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    71   1e-12
gi|153792074 proline rich 12 [Homo sapiens]                            68   1e-11
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    66   4e-11
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    60   4e-09
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    58   1e-08
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    58   1e-08
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    58   1e-08
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    58   1e-08
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 56   4e-08
gi|12751477 forkhead box L2 [Homo sapiens]                             55   7e-08
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                       54   2e-07
gi|146134388 YLP motif containing 1 [Homo sapiens]                     54   2e-07
gi|59938776 cAMP responsive element binding protein 5 isoform de...    54   3e-07
gi|59938774 cAMP responsive element binding protein 5 isoform be...    54   3e-07
gi|59938772 cAMP responsive element binding protein 5 isoform ga...    54   3e-07
gi|59938770 cAMP responsive element binding protein 5 isoform al...    54   3e-07
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]    52   6e-07
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]     52   6e-07
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]     52   6e-07
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]    52   6e-07
gi|205277421 Jun dimerization protein 2 isoform b [Homo sapiens]       52   6e-07
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    52   8e-07
gi|55741677 SET domain containing 1A [Homo sapiens]                    52   8e-07
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    52   8e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    52   8e-07

>gi|28872794 CCAAT/enhancer binding protein alpha [Homo sapiens]
          Length = 358

 Score =  749 bits (1933), Expect = 0.0
 Identities = 358/358 (100%), Positives = 358/358 (100%)

Query: 1   MESADFYEAEPRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHET 60
           MESADFYEAEPRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHET
Sbjct: 1   MESADFYEAEPRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHET 60

Query: 61  SIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVM 120
           SIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVM
Sbjct: 61  SIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVM 120

Query: 121 PGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFP 180
           PGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFP
Sbjct: 121 PGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFP 180

Query: 181 YQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPA 240
           YQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPA
Sbjct: 181 YQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPA 240

Query: 241 LGAAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVRRERNNIAVRKSR 300
           LGAAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVRRERNNIAVRKSR
Sbjct: 241 LGAAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVRRERNNIAVRKSR 300

Query: 301 DKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMGNCA 358
           DKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMGNCA
Sbjct: 301 DKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMGNCA 358


>gi|28872800 CCAAT/enhancer binding protein epsilon [Homo sapiens]
          Length = 281

 Score =  167 bits (424), Expect = 1e-41
 Identities = 129/337 (38%), Positives = 169/337 (50%), Gaps = 78/337 (23%)

Query: 34  PRGAG-PAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEKAK 92
           PRG   P +     A P  LG +CEHE SID+SAYI+     ++ L+DLF          
Sbjct: 11  PRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESG--EEQLLSDLF---------- 58

Query: 93  AAVGPTGGGGGGDFDYPGAPAGPGGAVM-PGGAHGPPPGYGCAAAGYLDGRLEPLYERVG 151
            AV P     G     PG PA P      P     PP  +G        G    +Y   G
Sbjct: 59  -AVKPAPEARG--LKGPGTPAFPHYLPPDPRPFAYPPHTFGPDRKALGPG----IYSSPG 111

Query: 152 APALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIA 211
           +   R + +K+EPR  + ++  +     P                         LQ+Q+A
Sbjct: 112 SYDPRAVAVKEEPRGPEGSRAASRGSYNP-------------------------LQYQVA 146

Query: 212 HCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSALKGLGA--------AHPDL 263
           HCGQT MHL       PPT               L  PG  L+ L A          P L
Sbjct: 147 HCGQTAMHL-------PPT---------------LAAPGQPLRVLKAPLATAAPPCSPLL 184

Query: 264 RASGGSGA-GKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDND 322
           +A   +G   K KK+V+K+S EYR+RRERNNIAVRKSRDKAK+R +ETQQKVLE  ++N+
Sbjct: 185 KAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYMAENE 244

Query: 323 RLRKRVEQLSRELDTLRGIFRQLPE-SSLVKAMGNCA 358
           RLR RVEQL++ELDTLR +FRQ+PE ++L+K +G C+
Sbjct: 245 RLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS 281


>gi|28872796 CCAAT/enhancer binding protein beta [Homo sapiens]
          Length = 345

 Score =  153 bits (386), Expect = 3e-37
 Identities = 125/360 (34%), Positives = 159/360 (44%), Gaps = 81/360 (22%)

Query: 28  SAAFGFPRGAGPAQPPAPPAAPEP----LGGICEHETSIDISAYIDPAAFNDEFLADLFQ 83
           +AA+G    A PA PPA    P P    LG I +HE +ID S Y++P             
Sbjct: 37  AAAYGGK--AAPAAPPAARPGPRPPAGELGSIGDHERAIDFSPYLEPLGAPQAPAPATAT 94

Query: 84  HSRQQEKAKAAVGPTGGGGGGDF-------DYPGAPAGPGGAVMPGGAHGPPPGYGCAAA 136
            + +      A  P   G   DF       DY G                 P  YG  + 
Sbjct: 95  DTFEAAPPAPAPAPASSGQHHDFLSDLFSDDYGGKNC------------KKPAEYGYVSL 142

Query: 137 GYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLF-PYQPPPPPPPSHPHPH 195
           G           R+GA                 AK     G F P  PPPPPP       
Sbjct: 143 G-----------RLGA-----------------AKGALHPGCFAPLHPPPPPP------- 167

Query: 196 PPPAHLAAPHLQFQIAHCGQT------------------TMHLQPGHPTPPPTPVPSPHP 237
           PPPA L A    F+ A C +                    +    G+   P     S   
Sbjct: 168 PPPAELKA-EPGFEPADCKRKEEAGAPGGGAGMAAGFPYALRAYLGYQAVPSGSSGSLST 226

Query: 238 APALGAAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVRRERNNIAVR 297
           + +    G P P  A     A +     +      KAKK+VDK+S+EY++RRERNNIAVR
Sbjct: 227 SSSSSPPGTPSPADAKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVR 286

Query: 298 KSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMGNC 357
           KSRDKAK RN+ETQ KVLELT++N+RL+K+VEQLSREL TLR +F+QLPE  L+ + G+C
Sbjct: 287 KSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPE-PLLASSGHC 345


>gi|28872798 CCAAT/enhancer binding protein delta [Homo sapiens]
          Length = 269

 Score =  119 bits (297), Expect = 5e-27
 Identities = 114/348 (32%), Positives = 147/348 (42%), Gaps = 114/348 (32%)

Query: 23  PHAPSSAAFGFPRGAG-PAQPPAPPAAPEP---LGGICEHETSIDISAYIDPAAF----- 73
           P     A F  P  AG P +   P A  EP      + + E++ID SAYID  A      
Sbjct: 16  PWPAEPAPFYEPGRAGKPGRGAEPGALGEPGAAAPAMYDDESAIDFSAYIDSMAAVPTLE 75

Query: 74  --NDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGY 131
             +DE  ADLF  + +             GG G  +           ++PGG    P G 
Sbjct: 76  LCHDELFADLFNSNHK------------AGGAGPLE-----------LLPGGP-ARPLGP 111

Query: 132 GCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSH 191
           G AA                     P ++K+EP   D     +L                
Sbjct: 112 GPAA---------------------PRLLKREPDWGDGDAPGSL---------------- 134

Query: 192 PHPHPPPAHLAAPHLQFQIAHCGQTTMHLQP-GHPTPPPTPVP---SPHPAPALGAAGLP 247
                         L  Q+A C QT + L   G PTPP +P P   SP   PA      P
Sbjct: 135 --------------LPAQVAACAQTVVSLAAAGQPTPPTSPEPPRSSPRQTPA------P 174

Query: 248 GPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRN 307
           GP                     AGK  +  D+ S EYR RRERNNIAVRKSRDKAK+RN
Sbjct: 175 GPARE----------------KSAGK--RGPDRGSPEYRQRRERNNIAVRKSRDKAKRRN 216

Query: 308 VETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMG 355
            E QQK++EL+++N++L +RVEQL+R+L  LR  F+QLP    + A G
Sbjct: 217 QEMQQKLVELSAENEKLHQRVEQLTRDLAGLRQFFKQLPSPPFLPAAG 264


>gi|4502769 CCAAT/enhancer binding protein gamma [Homo sapiens]
          Length = 150

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 42/91 (46%), Positives = 62/91 (68%), Gaps = 9/91 (9%)

Query: 261 PDLRASGGSGAGKA-------KKS--VDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQ 311
           P L  +G  G GKA       KKS  +D+NS+EYR RRERNN+AV+KSR K+KQ+  +T 
Sbjct: 32  PQLVPAGPGGGGKAVAPSKQSKKSSPMDRNSDEYRQRRERNNMAVKKSRLKSKQKAQDTL 91

Query: 312 QKVLELTSDNDRLRKRVEQLSRELDTLRGIF 342
           Q+V +L  +N+RL  +++ L++EL  L+ +F
Sbjct: 92  QRVNQLKEENERLEAKIKLLTKELSVLKDLF 122


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 83/275 (30%), Positives = 98/275 (35%), Gaps = 70/275 (25%)

Query: 20  QSPPHAPSSAAFGFPRGAGPAQP--------PAPPAA-----PEPLGGICEH-ETSIDIS 65
           + PP   +    G P+  GP  P        PAPPAA     PE   G C     +  ++
Sbjct: 88  EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVA 147

Query: 66  AYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGA- 124
           A  +PA       A           A+A  GP  G G G    PG PAGPG A    G+ 
Sbjct: 148 AGPEPAPAGPAKPA-----GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSA 202

Query: 125 ------HGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGL 178
                 H   P       G     L PL +    PA    VI+  P     A     A  
Sbjct: 203 ALLNSHHAAAPAVSLVNNG--PAALLPLPK----PAAPGTVIQTPPFVGAAAPPAPAAPS 256

Query: 179 FPYQPPPPPPPSHPHPHPP-PAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVP---- 233
            P  P P  P + P P PP PA LA P                 PGHP  PPT  P    
Sbjct: 257 PPAAPAPAAPAAAPPPPPPAPATLARP-----------------PGHPAGPPTAAPAVPP 299

Query: 234 ------------SPHPAPA----LGAAGLPGPGSA 252
                       +P PAPA     G +G PGPG+A
Sbjct: 300 PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 63/221 (28%), Positives = 72/221 (32%), Gaps = 49/221 (22%)

Query: 65  SAYIDPAAFNDEF----LADLFQHSRQQEKAKAA-----------VGPTGGGGGGDFDYP 109
           S  +D   FN E     ++DL      Q  A AA           V     G  G+    
Sbjct: 5   SDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVS 64

Query: 110 GAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLY---ERVGAPA-LRPLV------ 159
           G+PAG  GA     A G P   G A      GR  P     +R G P+  RPLV      
Sbjct: 65  GSPAGAAGAGPAAPAEGAP---GAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121

Query: 160 --IKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTT 217
              K  P  E  A   A        P P        P P PA  A P         G   
Sbjct: 122 PAAKLRPPPEGSAGSCA--------PVPAAAAVAAGPEPAPAGPAKP--------AGPAA 165

Query: 218 MHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSALKGLGA 258
           +  + G   P P P P P P P  G    PG    L G  A
Sbjct: 166 LAARAG---PGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAA 203



 Score = 35.4 bits (80), Expect = 0.079
 Identities = 38/118 (32%), Positives = 43/118 (36%), Gaps = 26/118 (22%)

Query: 14  PMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAF 73
           P +    SPP AP+ AA   P  A P  PPAP     P G      T+    A   PAA 
Sbjct: 249 PPAPAAPSPPAAPAPAA---PAAAPPPPPPAPATLARPPGHPAGPPTAAP--AVPPPAA- 302

Query: 74  NDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPG-GAHGPPPG 130
                      ++    A AA  P    GG        PAG  G   PG  A  P PG
Sbjct: 303 -----------AQNGGSAGAAPAPAPAAGG--------PAGVSGQPGPGAAAAAPAPG 341



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 62/258 (24%), Positives = 77/258 (29%), Gaps = 49/258 (18%)

Query: 11  PRPPMSSHLQSPPHAPSSAAFGFPR----------GAGPAQPPAPPAAPEPLGGICEHET 60
           P PP  + L  PP  P+      P           G+  A P   PAA  P G     + 
Sbjct: 272 PPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAG--VSGQP 329

Query: 61  SIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVM 120
               +A         E    + Q +    +  AA GP               A P  A +
Sbjct: 330 GPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAV 389

Query: 121 PGGAHGPPPGYGCAAAGYLDGRLE--PLYERVGAPA-LRPLVIKQEPREEDEAKQLALAG 177
           P  A G P G    AAG +   L   P     G  A L P V                  
Sbjct: 390 PPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTV------------------ 431

Query: 178 LFPYQPPPPPPPSHPHPHPPPAHL----------------AAPHLQFQIAHCGQTTMHLQ 221
           L P  P PP  P++      P  +                A   +Q Q     QTTM  +
Sbjct: 432 LAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPR 491

Query: 222 PGHPTPPPTPVPSPHPAP 239
           P  PT  P    S   AP
Sbjct: 492 PATPTSAPPVQISTVQAP 509


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 80/270 (29%), Positives = 92/270 (34%), Gaps = 69/270 (25%)

Query: 7    YEAEPRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEP-------LGGICEHE 59
            Y+A   PP+S     PP  P+       RG  P QPPA PA P P       LGG  E  
Sbjct: 1299 YQAGLTPPLSPPKSVPPSVPA-------RGLQP-QPPATPAVPHPPPSGAFGLGGALEAA 1350

Query: 60   TSIDISAYI-DPAAFNDEFLA---------------DLFQHSRQQEKAKAAVGPTGG--- 100
             S  +      P    DE L                 + ++   QE   +A+        
Sbjct: 1351 ESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPL 1410

Query: 101  GGGGDFDYP-GAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLV 159
             G  D   P G P  P  AV      GPPP  G  +A        PL E    P   P  
Sbjct: 1411 AGPKDTSTPDGPPLAPAAAVP-----GPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP 1465

Query: 160  IKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMH 219
              Q                 P  PPPPPPP    P PPP  L AP            +  
Sbjct: 1466 TPQ-----------------PQPPPPPPPPQPALPSPPP--LVAP----------TPSSP 1496

Query: 220  LQPGHPTPPPTPVPSPHPAPALGAAGLPGP 249
              P  P PPP  +PSP P P   AA L  P
Sbjct: 1497 PPPPLPPPPPPAMPSPPPPPPPAAAPLAAP 1526



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 66/279 (23%), Positives = 86/279 (30%), Gaps = 74/279 (26%)

Query: 7   YEAEPRP-PMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDIS 65
           + + P P P S  LQ PP +P +     P      +P   P  P  LG            
Sbjct: 157 FGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGF----------- 205

Query: 66  AYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDY-PGAPAGPGGAVMPGGA 124
                                ++      +GP G G      Y PG P  P         
Sbjct: 206 ---------------------ERLAGGGVLGPAGLGPAQTPPYRPGPPDPP--------- 235

Query: 125 HGPPPGY----------GCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLA 174
             PPP +            AAA   +     LY   GA    P   +  PR++   K   
Sbjct: 236 --PPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQ 293

Query: 175 LAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGH-PTPPPTPVP 233
                  QPPPPPPP+H   H                 CG +  +   GH      +P+ 
Sbjct: 294 RPA--SAQPPPPPPPAHALQH--------------YLSCGGS--YPSMGHRANLACSPLG 335

Query: 234 SPHPAPALGAAGLPGPGSALKGLGAAHPDLRASGGSGAG 272
              P+P  G     GP  A  G         A+GG GAG
Sbjct: 336 GGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAG 374



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 74/297 (24%), Positives = 97/297 (32%), Gaps = 53/297 (17%)

Query: 11  PRPPMSSHLQS----PPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISA 66
           P PP +S           A +S   G   GAG      PP  P  L    E      + +
Sbjct: 650 PSPPRTSGADGLVGEDGAADASKGLGGSGGAG-----GPPGTPYELAK--EDPQRYHLQS 702

Query: 67  YIDPAAFNDEFLADLFQ----HSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPG 122
            I  +A  DE      +      ++++K     G T  G      + GA A   GA +  
Sbjct: 703 VIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQK 762

Query: 123 GAHGPPPGYGCAAAGYLDGRLE------PLYERVGAPALRPLVIKQEPREEDEAKQLALA 176
               PPP             LE      PL      P L P V+   P     A ++ + 
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVH 822

Query: 177 GL-------FPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPP 229
            L        P  PPPPPPP  P P    AHL               +  L+P  P+P  
Sbjct: 823 LLEPATRDGAPQPPPPPPPPPPPMPLQLEAHL--------------RSHGLEPAAPSPRL 868

Query: 230 TPVPSPHPAPALGAAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYR 286
            P  S  P           PG+  + LGA  P   A G +G G         +  YR
Sbjct: 869 RPEESLDP-----------PGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYR 914



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 53/192 (27%), Positives = 64/192 (33%), Gaps = 29/192 (15%)

Query: 19   LQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDEFL 78
            L+  P AP     G P   G   P     +P P G      T       +    F D  L
Sbjct: 887  LEPLPPAPGDTGVGPPNSEGK-DPAGAYRSPSPQG------TKAPRFVPLTSICFPDSLL 939

Query: 79   ADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPG------YG 132
             D      ++          GGG   D+   G P   G    P    GPPPG      YG
Sbjct: 940  QD-----EERSFFPTMEEMFGGGAADDYGKAGPPEDEGD---PKAGAGPPPGPPAYDPYG 991

Query: 133  CAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHP 192
                G   G   P    +G    +P     E      A+ L L    P+Q  PPPPP   
Sbjct: 992  PYCPGRASGA-GPETPGLGLDPNKP----PELPSTVNAEPLGLIQSGPHQAAPPPPPP-- 1044

Query: 193  HPHPPPAHLAAP 204
             P PPPA  + P
Sbjct: 1045 -PPPPPAPASEP 1055



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 64/255 (25%), Positives = 80/255 (31%), Gaps = 67/255 (26%)

Query: 92  KAAVGPTGGGGGGDF----DYPGAPAGPGG-AVMPGGAHGPPP----------GYGCAAA 136
           +AA G   GGGGG +      PG   G GG     GGA  PPP            G  AA
Sbjct: 366 EAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAA 425

Query: 137 GYLDGRLEPLYERVGAP--------ALRPLVIKQE---PREEDEAKQLALAGLFPYQPPP 185
            Y  G+        G           L P    Q     + +D +K  + +G  P  P  
Sbjct: 426 AYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSG 485

Query: 186 PPPPS-------------------HPHPHPPPAH------LAAPHLQFQIAHCGQTTMH- 219
           PPPP                       P+P PA        A+P L +   H    + H 
Sbjct: 486 PPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHG 545

Query: 220 -------------LQPGHPTPPPTPVPSPHPAPALGAAGLPGP--GSALKGLGAAHPDLR 264
                          P H   P    P+    P +G+ G PG    S L       P   
Sbjct: 546 GGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGA 605

Query: 265 ASGGSGAGKAKKSVD 279
            S  +GAG  K   D
Sbjct: 606 GSYAAGAGGYKGKGD 620



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 71/268 (26%), Positives = 89/268 (33%), Gaps = 58/268 (21%)

Query: 13   PPMSSHLQSPPHAPSSAAFGF------PRGAGPAQPPAPPAAPEPLGGICEHETSIDISA 66
            P + SH  SP  +PS++  G        R   P  PP PP  P P+    E       S 
Sbjct: 803  PSVLSHAPSP--SPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLR---SH 857

Query: 67   YIDPAAFNDEFLAD--LFQHSRQQEKAKAA--VGPTGGGGGGDFDYPGAPAGPGGAVMPG 122
             ++PAA +     +  L      QE   A   + P  G  G      G P   G    P 
Sbjct: 858  GLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTG-----VGPPNSEGKD--PA 910

Query: 123  GAHGPPPGYGCAAAGYL--------DGRLE-------PLYERVGAPALRPLVIKQEPREE 167
            GA+  P   G  A  ++        D  L+       P  E +          K  P  E
Sbjct: 911  GAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGP-PE 969

Query: 168  DEAKQLALAGLFPYQPPPPPPPSHPH------------PHPPPAHL---AAPHLQFQIAH 212
            DE    A AG     PPP PP   P+            P  P   L     P L   +  
Sbjct: 970  DEGDPKAGAG-----PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNA 1024

Query: 213  CGQTTMHLQPGHPTPPPTPVPSPHPAPA 240
                 +   P    PPP P P P PAPA
Sbjct: 1025 EPLGLIQSGPHQAAPPPPPPPPPPPAPA 1052



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 42/156 (26%), Positives = 51/156 (32%), Gaps = 48/156 (30%)

Query: 30  AFGFPRGAGPAQ-----------PPAPPAAPEPLG-GICEHETSIDISA---------YI 68
           A+G   G G AQ           PP PP+ P P G   C+  +   +           Y 
Sbjct: 456 AYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYP 515

Query: 69  DPAAFNDEF------LADLFQHSRQQEKAKAAVGPTGGGGGGD---------FDYPGAPA 113
            PAA +         L+    HS          GP+  GGGG+            P A  
Sbjct: 516 GPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATG 575

Query: 114 GPGGAVMPGG---------AHGP---PPGYGCAAAG 137
            P G   PG          A  P   PPG G  AAG
Sbjct: 576 RPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAG 611


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 54/174 (31%), Positives = 64/174 (36%), Gaps = 40/174 (22%)

Query: 100 GGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLV 159
           GGGGG F   G   G GG         PPPG G      L+    P+    G    +P +
Sbjct: 10  GGGGGGFHRRGGGGGRGGL---HDFRSPPPGMG------LNQNRGPMGPGPGQSGPKPPI 60

Query: 160 IKQEPREEDEAKQLALAGLFPYQPPP-PPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTM 218
               P ++ +            QPPP  PPP  P PH PP H   PH Q Q         
Sbjct: 61  PPPPPHQQQQ------------QPPPQQPPPQQPPPHQPPPH-PQPHQQQQ--------- 98

Query: 219 HLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSALKGLGAAHPDLRASGGSGAG 272
                   PPP P  S  P  A G    PG GSA     +A P    + G+  G
Sbjct: 99  --------PPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG 144



 Score = 35.8 bits (81), Expect = 0.061
 Identities = 38/120 (31%), Positives = 42/120 (35%), Gaps = 23/120 (19%)

Query: 13  PPMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAA 72
           PP SS   +PP  P ++  G P G+GP   P PP A           T         P  
Sbjct: 125 PPASS--SAPPATPPTS--GAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPP- 179

Query: 73  FNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYG 132
                     Q         A  GP    G G    PG P GP G  MPG   GP PG G
Sbjct: 180 ----------QAGGPPPPPAAVPGP----GPGPKQGPG-PGGPKGGKMPG---GPKPGGG 221


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 66/259 (25%), Positives = 94/259 (36%), Gaps = 30/259 (11%)

Query: 1   MESADFYEAE-PRPPMSSHLQSPPHA--PSSAAFGFPRGAGPAQPPAPPAAPEPLGGICE 57
           M +A+  EA+ P PP++    SPP    P S +   P    P  P +PP  P P     +
Sbjct: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQ 450

Query: 58  HETSIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGG 117
            E   +    + PA  + +        S++ E+  A  GP G           +P  P  
Sbjct: 451 EEQE-ESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGT----------SPPTPTP 499

Query: 118 AVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAG 177
           +   GG     P     +  +L    + +   V A + R +   +   +ED  K   +  
Sbjct: 500 STATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEV 559

Query: 178 LFPYQPP---PPPPPSHPHPHPPPAHLAAPH-------------LQFQIAHCGQTTMHLQ 221
               +PP    PP P  P P P P     P              L+         T  L 
Sbjct: 560 SPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELP 619

Query: 222 PGHPTPPPTPVPSPHPAPA 240
           P  P PPP P PSP PAPA
Sbjct: 620 PPPPAPPPPPAPSPPPAPA 638



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 26/83 (31%), Positives = 30/83 (36%), Gaps = 17/83 (20%)

Query: 156 RPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQ 215
           R +  +  P  E E  +L    L P  P PPPP   P   PPP     P           
Sbjct: 384 RAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPP----------- 432

Query: 216 TTMHLQPGHPTPPPTPVPSPHPA 238
                 P   +PPP P P P PA
Sbjct: 433 ------PPPVSPPPLPSPPPPPA 449



 Score = 36.6 bits (83), Expect = 0.036
 Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 8/79 (10%)

Query: 162 QEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQ 221
           +E  E   A+++  A        PPPP + P P PPP  L  P        C        
Sbjct: 379 EEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPP-LPPPSTSPPPPLC-------P 430

Query: 222 PGHPTPPPTPVPSPHPAPA 240
           P  P   P P+PSP P PA
Sbjct: 431 PPPPPVSPPPLPSPPPPPA 449



 Score = 35.4 bits (80), Expect = 0.079
 Identities = 31/93 (33%), Positives = 36/93 (38%), Gaps = 7/93 (7%)

Query: 179  FPYQPPPPPPPSHPHPHPPPAHLAAPHL----QFQIAHCGQTTMHLQP-GHPTPPPTPVP 233
            FP  P     PS   P PPP+  A+P L    Q ++         L P      PP P P
Sbjct: 1906 FPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAP 1965

Query: 234  SPHPAPALGAAGLPGPGSALKGLGAAHPDLRAS 266
            SP P   LG          + GL AA  D  AS
Sbjct: 1966 SPPPPEDLGPDF--EDMEVVSGLSAADLDFAAS 1996



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 30/93 (32%), Positives = 34/93 (36%), Gaps = 6/93 (6%)

Query: 163 EPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQT--TMHL 220
           EPR       L+L    P    P    +   PH  PA    P  Q Q+    Q   T  L
Sbjct: 692 EPRAVGRTNHLSLPRFAPVVTTPVK--AEVSPHGAPALSNGPQTQAQLLQPLQALQTQLL 749

Query: 221 QPGHPTPPPT--PVPSPHPAPALGAAGLPGPGS 251
               P P P   P PSP   P L  A + G GS
Sbjct: 750 PQALPPPQPQLQPPPSPQQMPPLEKARIAGVGS 782



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 29/114 (25%), Positives = 45/114 (39%), Gaps = 16/114 (14%)

Query: 11   PRPP----------MSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHET 60
            PRPP           S  L+ PP  P+S        +G   PP P  +P P   +     
Sbjct: 1921 PRPPPSRWASPPLKTSPQLRVPP--PTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFE 1978

Query: 61   SIDISAYIDPAAFNDEFLADLFQHSRQQEK--AKAAVGPTGGGGGGDFDYPGAP 112
             +++ + +  A    +F A L      QE+  A  A+G + GG G   +   +P
Sbjct: 1979 DMEVVSGLSAADL--DFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSP 2030



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 42/163 (25%), Positives = 52/163 (31%), Gaps = 48/163 (29%)

Query: 95   VGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPA 154
            +G  G GG G  +    PA P        A+G  P  G  A+     R        GAP 
Sbjct: 2121 LGGPGDGGAGPREESLPPAPPL-------ANGSQPSQGLTASPADPTRTFAWLP--GAPG 2171

Query: 155  LRPLVIKQEPREEDEAKQ------------LALAGLFPYQPPPPPPPSHPHPHPPPAHLA 202
            +R L +   P     A              + +AG    +  P PPP    P PP     
Sbjct: 2172 VRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAG----EGEPVPPPVKQPPLPPTISPT 2227

Query: 203  APHLQFQIAHCGQTTMHLQPG------------HPTPPPTPVP 233
            AP           T+  L PG             P PPP P P
Sbjct: 2228 AP-----------TSWTLPPGPLLGVLPVVGVVRPAPPPPPPP 2259


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 61/194 (31%), Positives = 71/194 (36%), Gaps = 31/194 (15%)

Query: 92  KAAVGPTG----GGGGGDFDYPGAPAGPGGAVMPGGAHGP--PPGYGCAAAGYLDGRLEP 145
           K   GP G     G  GD   PG P  PG    PG A GP  PPGYG      L G    
Sbjct: 577 KGLPGPKGELALSGEKGDQGPPGDPGSPGS---PGPA-GPAGPPGYGPQGEPGLQGTQGV 632

Query: 146 LYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPH 205
                GAP          P E     +L+++   P  P PP PP HP P  PP       
Sbjct: 633 ----PGAPG--------PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG------ 674

Query: 206 LQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSALKGLG-AAHPDLR 264
           +   +  CG   +    G P  P    P P P P  G  G PG   +L   G    P L 
Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGP-PGPK-GDQGFPGTKGSLGCPGKMGEPGLP 732

Query: 265 ASGGSGAGKAKKSV 278
              G    K + +V
Sbjct: 733 GKPGLPGAKGEPAV 746



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 55/190 (28%), Positives = 68/190 (35%), Gaps = 36/190 (18%)

Query: 92  KAAVGPTGGGGG----------GDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDG 141
           K  +GP G  G           GD   PG P GP GA  P G  GPP   G   +     
Sbjct: 332 KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP-GPRGARGPQGPSGPPGVPGSPGSSRPGL 390

Query: 142 RLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGL-----FPYQPPPPPPPSH----- 191
           R  P     G P L+    ++    +D        G       P  P PP PP       
Sbjct: 391 RGAP-----GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 192 --PHPHPPPAHLAAPHLQFQIAHCGQTTMHLQ--PGHPTPPPTP-VPSPHPAPAL----G 242
             P  H  P +L +P +       G+  +     P  P PP  P +P  H    +    G
Sbjct: 446 GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 243 AAGLPG-PGS 251
           AAGL G PGS
Sbjct: 506 AAGLKGSPGS 515



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 56/229 (24%), Positives = 69/229 (30%), Gaps = 36/229 (15%)

Query: 8    EAEPRPPMSSH-LQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISA 66
            +A PR P        PP  P +   G     GP      P AP P G    H   I    
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGI---- 1266

Query: 67   YIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTG-GGGGGDFDYPGAPAGPGGAVMPGGAH 125
                               +  + +    GP G  G  GD   PG    PG   +P G  
Sbjct: 1267 -------------------KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP-GPR 1306

Query: 126  GPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPP 185
            G P   G        G        +G P   P+  K  P    +   L +  L P  P P
Sbjct: 1307 GDPGFQGFPGVKGEKGN-PGFLGSIGPPG--PIGPKGPPGVRGDPGTLKIISL-PGSPGP 1362

Query: 186  PPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPS 234
            P  P  P     P     P     +  CG      +PG    P TP P+
Sbjct: 1363 PGTPGEPGMQGEPGPPGPPG---NLGPCGPRG---KPGKDGKPGTPGPA 1405



 Score = 32.0 bits (71), Expect = 0.88
 Identities = 43/163 (26%), Positives = 53/163 (32%), Gaps = 25/163 (15%)

Query: 96   GPTGGGGGGDFDYPGAPAGPGGAVMPG--GAHGPPPGYGCAAAGYLDGRLEPLYERVGAP 153
            GPTG  G     +PG P  PG A++PG  G  GPP   G   A              G P
Sbjct: 1216 GPTGIEG-----FPGPPGLPG-AIIPGQTGNRGPPGSRGSPGAP----------GPPGPP 1259

Query: 154  ALRPLVIKQEPREEDEAKQLALAGLFPYQPPP-----PPPPSHPHPHPPPAHLAAPHLQF 208
                + IK +             G      PP     P  P  P P   P     P ++ 
Sbjct: 1260 GSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG 1319

Query: 209  QIAHCGQTTMHLQPG--HPTPPPTPVPSPHPAPALGAAGLPGP 249
            +  + G       PG   P  PP     P     +   G PGP
Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 69/267 (25%), Positives = 89/267 (33%), Gaps = 58/267 (21%)

Query: 23   PHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDEFLADLF 82
            P  P +     PRG  P QP  PP    P G   E          ++             
Sbjct: 779  PGTPGNEGLDGPRG-DPGQP-GPPGEQGPPGRCIEGPRGAQGLPGLNGL----------- 825

Query: 83   QHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGR 142
               + Q+  +   GP G  G    D  G P   G   +PG                  G 
Sbjct: 826  ---KGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGH----------------QGE 866

Query: 143  LEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLA 202
            + PL +R G P   P ++   P  ED    + + G FP    PP PP +P          
Sbjct: 867  MGPLGQR-GYPG-NPGIL--GPPGEDGV--IGMMG-FPGAIGPPGPPGNPGTPGQRGSPG 919

Query: 203  APHLQFQIAHCGQTTMHLQPGHPTPPP-TPVPSPHPAPAL-GAAGLPG-------PG--- 250
             P ++ Q    G        G+P P   + V      P L G AG PG       PG   
Sbjct: 920  IPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPG 979

Query: 251  -SALKGL-GAAHP-----DLRASGGSG 270
               LKGL G A P     DL ++G  G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPG 1006



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 49/176 (27%), Positives = 59/176 (33%), Gaps = 49/176 (27%)

Query: 97  PTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALR 156
           P   G  G+  +PG P   G   +PG            AAG        L  + GAPA  
Sbjct: 123 PGCSGSKGEQGFPGLPGTLGYPGIPG------------AAG--------LKGQKGAPA-- 160

Query: 157 PLVIKQEPREEDEAKQLALAGLFPYQPPPPPP--PSHPHPHPPPAHLAAP---------- 204
               K+E  E D      L G    Q  P PP  P    P  PP     P          
Sbjct: 161 ----KEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 205 HL-QFQIAHCGQTTMHLQPGHPTPPPTPV---PSPHPAPAL-------GAAGLPGP 249
           H+ +  I H G+  +    G P PP T +     P     L       GA G PGP
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 61/194 (31%), Positives = 71/194 (36%), Gaps = 31/194 (15%)

Query: 92  KAAVGPTG----GGGGGDFDYPGAPAGPGGAVMPGGAHGP--PPGYGCAAAGYLDGRLEP 145
           K   GP G     G  GD   PG P  PG    PG A GP  PPGYG      L G    
Sbjct: 577 KGLPGPKGELALSGEKGDQGPPGDPGSPGS---PGPA-GPAGPPGYGPQGEPGLQGTQGV 632

Query: 146 LYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPH 205
                GAP          P E     +L+++   P  P PP PP HP P  PP       
Sbjct: 633 ----PGAPG--------PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG------ 674

Query: 206 LQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSALKGLG-AAHPDLR 264
           +   +  CG   +    G P  P    P P P P  G  G PG   +L   G    P L 
Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGP-PGPK-GDQGFPGTKGSLGCPGKMGEPGLP 732

Query: 265 ASGGSGAGKAKKSV 278
              G    K + +V
Sbjct: 733 GKPGLPGAKGEPAV 746



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 65/259 (25%), Positives = 80/259 (30%), Gaps = 39/259 (15%)

Query: 8    EAEPRPPMSSH-LQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISA 66
            +A PR P        PP  P +   G     GP      P AP P G    H   I    
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGI---- 1266

Query: 67   YIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTG-GGGGGDFDYPGAPAGPGGAVMPGGAH 125
                               +  + +    GP G  G  GD   PG    PG   +P G  
Sbjct: 1267 -------------------KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP-GPR 1306

Query: 126  GPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPP 185
            G P   G        G        +G P   P+  K  P    +   L +  L P  P P
Sbjct: 1307 GDPGFQGFPGVKGEKGN-PGFLGSIGPPG--PIGPKGPPGVRGDPGTLKIISL-PGSPGP 1362

Query: 186  PPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAG 245
            P  P  P     P     P     +  CG      +PG    P TP P+       G+ G
Sbjct: 1363 PGTPGEPGMQGEPGPPGPPG---NLGPCGPRG---KPGKDGKPGTPGPAGEKGNK-GSKG 1415

Query: 246  LPGPGSA--LKGLGAAHPD 262
             PGP  +  L GL     D
Sbjct: 1416 EPGPAGSDGLPGLKGKRGD 1434



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 55/190 (28%), Positives = 68/190 (35%), Gaps = 36/190 (18%)

Query: 92  KAAVGPTGGGGG----------GDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDG 141
           K  +GP G  G           GD   PG P GP GA  P G  GPP   G   +     
Sbjct: 332 KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP-GPRGARGPQGPSGPPGVPGSPGSSRPGL 390

Query: 142 RLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGL-----FPYQPPPPPPPSH----- 191
           R  P     G P L+    ++    +D        G       P  P PP PP       
Sbjct: 391 RGAP-----GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 192 --PHPHPPPAHLAAPHLQFQIAHCGQTTMHLQ--PGHPTPPPTP-VPSPHPAPAL----G 242
             P  H  P +L +P +       G+  +     P  P PP  P +P  H    +    G
Sbjct: 446 GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 243 AAGLPG-PGS 251
           AAGL G PGS
Sbjct: 506 AAGLKGSPGS 515



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 69/267 (25%), Positives = 89/267 (33%), Gaps = 58/267 (21%)

Query: 23   PHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDEFLADLF 82
            P  P +     PRG  P QP  PP    P G   E          ++             
Sbjct: 779  PGTPGNEGLDGPRG-DPGQP-GPPGEQGPPGRCIEGPRGAQGLPGLNGL----------- 825

Query: 83   QHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGR 142
               + Q+  +   GP G  G    D  G P   G   +PG                  G 
Sbjct: 826  ---KGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGH----------------QGE 866

Query: 143  LEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLA 202
            + PL +R G P   P ++   P  ED    + + G FP    PP PP +P          
Sbjct: 867  MGPLGQR-GYPG-NPGIL--GPPGEDGV--IGMMG-FPGAIGPPGPPGNPGTPGQRGSPG 919

Query: 203  APHLQFQIAHCGQTTMHLQPGHPTPPP-TPVPSPHPAPAL-GAAGLPG-------PG--- 250
             P ++ Q    G        G+P P   + V      P L G AG PG       PG   
Sbjct: 920  IPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPG 979

Query: 251  -SALKGL-GAAHP-----DLRASGGSG 270
               LKGL G A P     DL ++G  G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPG 1006



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 49/176 (27%), Positives = 59/176 (33%), Gaps = 49/176 (27%)

Query: 97  PTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALR 156
           P   G  G+  +PG P   G   +PG            AAG        L  + GAPA  
Sbjct: 123 PGCSGSKGEQGFPGLPGTLGYPGIPG------------AAG--------LKGQKGAPA-- 160

Query: 157 PLVIKQEPREEDEAKQLALAGLFPYQPPPPPP--PSHPHPHPPPAHLAAP---------- 204
               K+E  E D      L G    Q  P PP  P    P  PP     P          
Sbjct: 161 ----KEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 205 HL-QFQIAHCGQTTMHLQPGHPTPPPTPV---PSPHPAPAL-------GAAGLPGP 249
           H+ +  I H G+  +    G P PP T +     P     L       GA G PGP
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 61/194 (31%), Positives = 71/194 (36%), Gaps = 31/194 (15%)

Query: 92  KAAVGPTG----GGGGGDFDYPGAPAGPGGAVMPGGAHGP--PPGYGCAAAGYLDGRLEP 145
           K   GP G     G  GD   PG P  PG    PG A GP  PPGYG      L G    
Sbjct: 577 KGLPGPKGELALSGEKGDQGPPGDPGSPGS---PGPA-GPAGPPGYGPQGEPGLQGTQGV 632

Query: 146 LYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPH 205
                GAP          P E     +L+++   P  P PP PP HP P  PP       
Sbjct: 633 ----PGAPG--------PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG------ 674

Query: 206 LQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSALKGLG-AAHPDLR 264
           +   +  CG   +    G P  P    P P P P  G  G PG   +L   G    P L 
Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGP-PGPK-GDQGFPGTKGSLGCPGKMGEPGLP 732

Query: 265 ASGGSGAGKAKKSV 278
              G    K + +V
Sbjct: 733 GKPGLPGAKGEPAV 746



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 65/259 (25%), Positives = 80/259 (30%), Gaps = 39/259 (15%)

Query: 8    EAEPRPPMSSH-LQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISA 66
            +A PR P        PP  P +   G     GP      P AP P G    H   I    
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGI---- 1266

Query: 67   YIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTG-GGGGGDFDYPGAPAGPGGAVMPGGAH 125
                               +  + +    GP G  G  GD   PG    PG   +P G  
Sbjct: 1267 -------------------KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP-GPR 1306

Query: 126  GPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPP 185
            G P   G        G        +G P   P+  K  P    +   L +  L P  P P
Sbjct: 1307 GDPGFQGFPGVKGEKGN-PGFLGSIGPPG--PIGPKGPPGVRGDPGTLKIISL-PGSPGP 1362

Query: 186  PPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAG 245
            P  P  P     P     P     +  CG      +PG    P TP P+       G+ G
Sbjct: 1363 PGTPGEPGMQGEPGPPGPPG---NLGPCGPRG---KPGKDGKPGTPGPAGEKGNK-GSKG 1415

Query: 246  LPGPGSA--LKGLGAAHPD 262
             PGP  +  L GL     D
Sbjct: 1416 EPGPAGSDGLPGLKGKRGD 1434



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 55/190 (28%), Positives = 68/190 (35%), Gaps = 36/190 (18%)

Query: 92  KAAVGPTGGGGG----------GDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDG 141
           K  +GP G  G           GD   PG P GP GA  P G  GPP   G   +     
Sbjct: 332 KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP-GPRGARGPQGPSGPPGVPGSPGSSRPGL 390

Query: 142 RLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGL-----FPYQPPPPPPPSH----- 191
           R  P     G P L+    ++    +D        G       P  P PP PP       
Sbjct: 391 RGAP-----GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 192 --PHPHPPPAHLAAPHLQFQIAHCGQTTMHLQ--PGHPTPPPTP-VPSPHPAPAL----G 242
             P  H  P +L +P +       G+  +     P  P PP  P +P  H    +    G
Sbjct: 446 GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 243 AAGLPG-PGS 251
           AAGL G PGS
Sbjct: 506 AAGLKGSPGS 515



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 69/267 (25%), Positives = 89/267 (33%), Gaps = 58/267 (21%)

Query: 23   PHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDEFLADLF 82
            P  P +     PRG  P QP  PP    P G   E          ++             
Sbjct: 779  PGTPGNEGLDGPRG-DPGQP-GPPGEQGPPGRCIEGPRGAQGLPGLNGL----------- 825

Query: 83   QHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGR 142
               + Q+  +   GP G  G    D  G P   G   +PG                  G 
Sbjct: 826  ---KGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGH----------------QGE 866

Query: 143  LEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLA 202
            + PL +R G P   P ++   P  ED    + + G FP    PP PP +P          
Sbjct: 867  MGPLGQR-GYPG-NPGIL--GPPGEDGV--IGMMG-FPGAIGPPGPPGNPGTPGQRGSPG 919

Query: 203  APHLQFQIAHCGQTTMHLQPGHPTPPP-TPVPSPHPAPAL-GAAGLPG-------PG--- 250
             P ++ Q    G        G+P P   + V      P L G AG PG       PG   
Sbjct: 920  IPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPG 979

Query: 251  -SALKGL-GAAHP-----DLRASGGSG 270
               LKGL G A P     DL ++G  G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPG 1006



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 49/176 (27%), Positives = 59/176 (33%), Gaps = 49/176 (27%)

Query: 97  PTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALR 156
           P   G  G+  +PG P   G   +PG            AAG        L  + GAPA  
Sbjct: 123 PGCSGSKGEQGFPGLPGTLGYPGIPG------------AAG--------LKGQKGAPA-- 160

Query: 157 PLVIKQEPREEDEAKQLALAGLFPYQPPPPPP--PSHPHPHPPPAHLAAP---------- 204
               K+E  E D      L G    Q  P PP  P    P  PP     P          
Sbjct: 161 ----KEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 205 HL-QFQIAHCGQTTMHLQPGHPTPPPTPV---PSPHPAPAL-------GAAGLPGP 249
           H+ +  I H G+  +    G P PP T +     P     L       GA G PGP
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1670

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 61/194 (31%), Positives = 71/194 (36%), Gaps = 31/194 (15%)

Query: 92  KAAVGPTG----GGGGGDFDYPGAPAGPGGAVMPGGAHGP--PPGYGCAAAGYLDGRLEP 145
           K   GP G     G  GD   PG P  PG    PG A GP  PPGYG      L G    
Sbjct: 577 KGLPGPKGELALSGEKGDQGPPGDPGSPGS---PGPA-GPAGPPGYGPQGEPGLQGTQGV 632

Query: 146 LYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPH 205
                GAP          P E     +L+++   P  P PP PP HP P  PP       
Sbjct: 633 ----PGAPG--------PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG------ 674

Query: 206 LQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSALKGLG-AAHPDLR 264
           +   +  CG   +    G P  P    P P P P  G  G PG   +L   G    P L 
Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGP-PGPK-GDQGFPGTKGSLGCPGKMGEPGLP 732

Query: 265 ASGGSGAGKAKKSV 278
              G    K + +V
Sbjct: 733 GKPGLPGAKGEPAV 746



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 65/259 (25%), Positives = 80/259 (30%), Gaps = 39/259 (15%)

Query: 8    EAEPRPPMSSH-LQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISA 66
            +A PR P        PP  P +   G     GP      P AP P G    H   I    
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGI---- 1266

Query: 67   YIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTG-GGGGGDFDYPGAPAGPGGAVMPGGAH 125
                               +  + +    GP G  G  GD   PG    PG   +P G  
Sbjct: 1267 -------------------KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLP-GPR 1306

Query: 126  GPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPP 185
            G P   G        G        +G P   P+  K  P    +   L +  L P  P P
Sbjct: 1307 GDPGFQGFPGVKGEKGN-PGFLGSIGPPG--PIGPKGPPGVRGDPGTLKIISL-PGSPGP 1362

Query: 186  PPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAG 245
            P  P  P     P     P     +  CG      +PG    P TP P+       G+ G
Sbjct: 1363 PGTPGEPGMQGEPGPPGPPG---NLGPCGPRG---KPGKDGKPGTPGPAGEKGNK-GSKG 1415

Query: 246  LPGPGSA--LKGLGAAHPD 262
             PGP  +  L GL     D
Sbjct: 1416 EPGPAGSDGLPGLKGKRGD 1434



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 55/190 (28%), Positives = 68/190 (35%), Gaps = 36/190 (18%)

Query: 92  KAAVGPTGGGGG----------GDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDG 141
           K  +GP G  G           GD   PG P GP GA  P G  GPP   G   +     
Sbjct: 332 KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP-GPRGARGPQGPSGPPGVPGSPGSSRPGL 390

Query: 142 RLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGL-----FPYQPPPPPPPSH----- 191
           R  P     G P L+    ++    +D        G       P  P PP PP       
Sbjct: 391 RGAP-----GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 192 --PHPHPPPAHLAAPHLQFQIAHCGQTTMHLQ--PGHPTPPPTP-VPSPHPAPAL----G 242
             P  H  P +L +P +       G+  +     P  P PP  P +P  H    +    G
Sbjct: 446 GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 243 AAGLPG-PGS 251
           AAGL G PGS
Sbjct: 506 AAGLKGSPGS 515



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 69/267 (25%), Positives = 89/267 (33%), Gaps = 58/267 (21%)

Query: 23   PHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDEFLADLF 82
            P  P +     PRG  P QP  PP    P G   E          ++             
Sbjct: 779  PGTPGNEGLDGPRG-DPGQP-GPPGEQGPPGRCIEGPRGAQGLPGLNGL----------- 825

Query: 83   QHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGR 142
               + Q+  +   GP G  G    D  G P   G   +PG                  G 
Sbjct: 826  ---KGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGH----------------QGE 866

Query: 143  LEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLA 202
            + PL +R G P   P ++   P  ED    + + G FP    PP PP +P          
Sbjct: 867  MGPLGQR-GYPG-NPGIL--GPPGEDGV--IGMMG-FPGAIGPPGPPGNPGTPGQRGSPG 919

Query: 203  APHLQFQIAHCGQTTMHLQPGHPTPPP-TPVPSPHPAPAL-GAAGLPG-------PG--- 250
             P ++ Q    G        G+P P   + V      P L G AG PG       PG   
Sbjct: 920  IPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPG 979

Query: 251  -SALKGL-GAAHP-----DLRASGGSG 270
               LKGL G A P     DL ++G  G
Sbjct: 980  LKGLKGLPGPAGPPGPRGDLGSTGNPG 1006



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 49/176 (27%), Positives = 59/176 (33%), Gaps = 49/176 (27%)

Query: 97  PTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALR 156
           P   G  G+  +PG P   G   +PG            AAG        L  + GAPA  
Sbjct: 123 PGCSGSKGEQGFPGLPGTLGYPGIPG------------AAG--------LKGQKGAPA-- 160

Query: 157 PLVIKQEPREEDEAKQLALAGLFPYQPPPPPP--PSHPHPHPPPAHLAAP---------- 204
               K+E  E D      L G    Q  P PP  P    P  PP     P          
Sbjct: 161 ----KEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 205 HL-QFQIAHCGQTTMHLQPGHPTPPPTPV---PSPHPAPAL-------GAAGLPGP 249
           H+ +  I H G+  +    G P PP T +     P     L       GA G PGP
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 53/177 (29%), Positives = 62/177 (35%), Gaps = 37/177 (20%)

Query: 80  DLFQHSRQQEKAKAAVGPTGGGG-----GGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCA 134
           +L Q    Q + +  VG +G  G     G     PGAP GP     PG A GPPP     
Sbjct: 581 NLLQLRPPQPQPQGTVGASGATGQPQPQGTAQPPPGAPQGP-----PGAASGPPPP---- 631

Query: 135 AAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHP 194
                             P LRP    Q P    + + L L    P    PPP  S  H 
Sbjct: 632 -----------------GPILRP----QNPGANPQLRSLLLNPPPPQTGVPPPQASLHHL 670

Query: 195 HPP--PAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGP 249
            PP  PA L  PH        G   +H  P    P   P  +P P   L + G  GP
Sbjct: 671 QPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGP 727



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 45/179 (25%), Positives = 59/179 (32%), Gaps = 39/179 (21%)

Query: 80  DLFQHSRQQEKAKAAVGPTGGGGG-----GDFDYPGAPAGPGGAVMPGGAHGPPPGYGCA 134
           D+ Q  R     +  V P GGG            P  PA P GA +      P P     
Sbjct: 212 DVSQDPRHMVLVRGLVLPVGGGSAPGPLQSKQPVPLPPAAPSGATLSAAPQQPLPP---- 267

Query: 135 AAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFP-YQPPPPPPPSHPH 193
                   + P Y+  G  +   +  +       EA +   AGL P + P  P   + P 
Sbjct: 268 --------VPPQYQVPGNLSAAQVAAQNAV----EAAKNQKAGLGPRFSPITPLQQAAPG 315

Query: 194 PHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSA 252
             PP +   AP L                  P PP  P P P   P+L +   PG G A
Sbjct: 316 VGPPFSQAPAPQLP-----------------PGPPGAPKPPPASQPSLVSTVAPGSGLA 357



 Score = 35.8 bits (81), Expect = 0.061
 Identities = 41/130 (31%), Positives = 51/130 (39%), Gaps = 10/130 (7%)

Query: 151 GAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHP-HPPPAHLAAPHL--- 206
           G  A  PL  KQ       A   A     P QP PP PP +  P +   A +AA +    
Sbjct: 232 GGSAPGPLQSKQPVPLPPAAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEA 291

Query: 207 -QFQIAHCGQTTMHLQPGHPTPPPTPVP-SPHPAPALGAAGLPGPGSALKGLGAAHPDLR 264
            + Q A  G     + P     P    P S  PAP L     PGP  A K   A+ P L 
Sbjct: 292 AKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAPQLP----PGPPGAPKPPPASQPSLV 347

Query: 265 ASGGSGAGKA 274
           ++   G+G A
Sbjct: 348 STVAPGSGLA 357



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 54/220 (24%), Positives = 75/220 (34%), Gaps = 52/220 (23%)

Query: 10  EPRPPMSSHLQSPPHAPSSAAFGFPRGAGPA-------QP-PAPPAAP----------EP 51
           EP  P +   Q P H         P G G A       QP P PPAAP          +P
Sbjct: 205 EPLQPPTDVSQDPRHMVLVRGLVLPVGGGSAPGPLQSKQPVPLPPAAPSGATLSAAPQQP 264

Query: 52  LGGI-CEHETSIDISA-------YIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGG 103
           L  +  +++   ++SA        ++ A      L   F      ++A   VGP      
Sbjct: 265 LPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAP 324

Query: 104 GDFDYPGAP----------------AGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLY 147
                PG P                  PG  + P    G P   G  A G + G   P  
Sbjct: 325 APQLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPSMAGTVAPGGVSG---PSP 381

Query: 148 ERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPP 187
            ++GAPAL         ++    K LA +G+  +Q  P P
Sbjct: 382 AQLGAPAL-------GGQQSVSNKLLAWSGVLEWQEKPKP 414


>gi|12751477 forkhead box L2 [Homo sapiens]
          Length = 376

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 54/177 (30%), Positives = 59/177 (33%), Gaps = 46/177 (25%)

Query: 85  SRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLE 144
           S Q   A AA        G        P  PG A +  G  GP   YG            
Sbjct: 217 SCQMAAAAAAAAAAAAAAG--------PGSPGAAAVVKGLAGPAASYGP----------- 257

Query: 145 PLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHL--- 201
             Y RV + AL P V+              L G     P  PPPP HPHPHP   HL   
Sbjct: 258 --YTRVQSMALPPGVVNSYN---------GLGG----PPAAPPPPPHPHPHPHAHHLHAA 302

Query: 202 -----AAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSAL 253
                A PH        GQ    L P  P     P P+P  AP L  A    P  A+
Sbjct: 303 AAPPPAPPHHGAAAPPPGQ----LSPASPATAAPPAPAPTSAPGLQFACARQPELAM 355


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 50/192 (26%), Positives = 59/192 (30%), Gaps = 30/192 (15%)

Query: 94  AVGPTGGGGGGDFDYPGAPAGPGGAVMPGGA-------HGPPPGYGCAAAGYLDGRLE-- 144
           A G  GGGGGG     G   G GG + PG A        G P       + ++ G +   
Sbjct: 26  AAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAAS 85

Query: 145 -------------PLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSH 191
                               A A        E         + +AG  P QPP PPPP  
Sbjct: 86  NGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAG-SPQQPPQPPPP-- 142

Query: 192 PHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGS 251
               PP              H G    H  P H  PPP P    HP    GAA      +
Sbjct: 143 ----PPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPG-GWGAAAAAAAAA 197

Query: 252 ALKGLGAAHPDL 263
           A     A  P +
Sbjct: 198 AAAAAAAHLPSM 209



 Score = 28.5 bits (62), Expect = 9.7
 Identities = 15/44 (34%), Positives = 17/44 (38%), Gaps = 5/44 (11%)

Query: 7   YEAEPRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPE 50
           + A P PP   H Q PPH           GAGP      P + E
Sbjct: 276 HHAHPHPPHPHHAQGPPHHGGGGG-----GAGPGLNSHDPHSDE 314


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 55/224 (24%), Positives = 81/224 (36%), Gaps = 46/224 (20%)

Query: 35  RGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAA--------FNDEFLADLFQHSR 86
           R  G +  P PP  P P   + E       S+   PAA        F ++ LA L Q  +
Sbjct: 7   RYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQ 66

Query: 87  QQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHG----------PPPGYGCAAA 136
             +K    V            +   P  P   VMPGG +G          PPPG   +  
Sbjct: 67  MHQKQMQCVLQP--------HHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQ 118

Query: 137 GYLDGRLEPLY-ERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPH 195
                + + L+ +R G P L P+ ++  P          +     Y PPP PPPS+   +
Sbjct: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSY---Y 175

Query: 196 PPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAP 239
           PP +                +  +L P  P+P  +P    + AP
Sbjct: 176 PPTS----------------SQPYLPPAQPSPSQSPPSQSYLAP 203



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 18/81 (22%)

Query: 164  PREEDEAKQLALAGLFP----YQPPPP---PPPSHPHPHPPPAHLAAPHLQFQIAHCGQT 216
            P+E       +  G++P    Y+PPPP   PP S   P  PPA  + P            
Sbjct: 1491 PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVP-----------V 1539

Query: 217  TMHLQPGHPTPPPTPVPSPHP 237
            T    P  P PPP P+P P P
Sbjct: 1540 TRPPVPIPPPPPPPPLPPPPP 1560



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 42/159 (26%), Positives = 60/159 (37%), Gaps = 27/159 (16%)

Query: 97  PTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCA-------AAGYLDGR------- 142
           P  G  GG   YP  P  P   V    A  P PGY  +       ++G++  R       
Sbjct: 3   PNWGRYGGSSHYPPPPVPPPPPVALPEA-SPGPGYSSSTTPAAPSSSGFMSFREQHLAQL 61

Query: 143 --LEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAH 200
             L+ ++++     L+P  +   P        +   G   +QPPPPP P      PPP  
Sbjct: 62  QQLQQMHQKQMQCVLQPHHLPPPPLPPPPV--MPGGGYGDWQPPPPPMP------PPPGP 113

Query: 201 LAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAP 239
             +   Q Q  H  Q   H + G P   P  + SP  +P
Sbjct: 114 ALSYQKQQQYKH--QMLHHQRDGPPGLVPMELESPPESP 150



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 31/90 (34%), Positives = 33/90 (36%), Gaps = 20/90 (22%)

Query: 180 PYQPPPPPPPSHPHPHPPPAHL-----AAP-----------HL----QFQIAHCGQTTMH 219
           P   PPPPP + P   P P +      AAP           HL    Q Q  H  Q    
Sbjct: 16  PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75

Query: 220 LQPGHPTPPPTPVPSPHPAPALGAAGLPGP 249
           LQP H  PPP P P   P    G    P P
Sbjct: 76  LQPHHLPPPPLPPPPVMPGGGYGDWQPPPP 105



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 26/68 (38%), Positives = 29/68 (42%), Gaps = 10/68 (14%)

Query: 180 PYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAP 239
           P  PPP  PPS P P  PPA      L   +   G       P  P   PT VP P   P
Sbjct: 531 PTMPPPVLPPSLPPPVMPPA------LPATVPPPGMP----PPVMPPSLPTSVPPPGMPP 580

Query: 240 ALGAAGLP 247
           +L +AG P
Sbjct: 581 SLSSAGPP 588



 Score = 32.7 bits (73), Expect = 0.51
 Identities = 24/82 (29%), Positives = 27/82 (32%), Gaps = 25/82 (30%)

Query: 117  GAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALA 176
            G   P G++ PPP  G      +     P   R   P  RP V                 
Sbjct: 1504 GMYPPPGSYRPPPPMGKPPGSIVRPSAPPA--RSSVPVTRPPV----------------- 1544

Query: 177  GLFPYQPPPPPPPSHPHPHPPP 198
                  P PPPPP  P P PPP
Sbjct: 1545 ------PIPPPPPPPPLPPPPP 1560



 Score = 32.0 bits (71), Expect = 0.88
 Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 6/69 (8%)

Query: 183 PPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPG-HPTPPPTPVPSPHPAPAL 241
           PPP  PPS     PPP  L  P L    +  G   +   P    T PP  +P P  + A 
Sbjct: 574 PPPGMPPSLSSAGPPPV-LPPPSL----SSAGPPPVLPPPSLSSTAPPPVMPLPPLSSAT 628

Query: 242 GAAGLPGPG 250
              G+P PG
Sbjct: 629 PPPGIPPPG 637



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 43/150 (28%), Positives = 58/150 (38%), Gaps = 25/150 (16%)

Query: 150 VGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPP-----PPPPSHPHP----HPPPAH 200
           V  P + P +    P        L+ AG  P  PPP      PPP  P P      PP  
Sbjct: 573 VPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPG 632

Query: 201 LAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSALKGLGAA- 259
           +  P +   I    Q T    P   +   + VP   P PAL    LP P S     G+A 
Sbjct: 633 IPPPGVPQGIP--PQLTAAPVPPASSSQSSQVPE-KPRPAL----LPTPVS----FGSAP 681

Query: 260 ----HPDLRASGGSGAGKAKKSVDKNSNEY 285
               HP L+++G S    +K  + K++  Y
Sbjct: 682 PTTYHPPLQSAGPSEQVNSKAPLSKSALPY 711



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 23/81 (28%), Positives = 27/81 (33%), Gaps = 17/81 (20%)

Query: 144 EPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPP-----PPPPPSHPHPHPPP 198
           EP+ E V  PA     + + P  E+           P  PP     PP PP  P    P 
Sbjct: 328 EPVKEEVTVPATSQ--VPESPSSEEP----------PLPPPNEEVPPPLPPEEPQSEDPE 375

Query: 199 AHLAAPHLQFQIAHCGQTTMH 219
                  LQ   AH  Q   H
Sbjct: 376 EDARLKQLQAAAAHWQQHQQH 396


>gi|59938776 cAMP responsive element binding protein 5 isoform delta
           [Homo sapiens]
          Length = 369

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 44/158 (27%), Positives = 65/158 (41%), Gaps = 14/158 (8%)

Query: 186 PPPPSHPHPHPPPAHLAAP---HLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALG 242
           PP   +PH H  PAH   P   H Q    H   + +H  P H         SPHP    G
Sbjct: 146 PPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQT------SPHPPLHTG 199

Query: 243 AAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVR-RERNNIAVRKSRD 301
                 P +            + +GG    + ++ VD++ +E R +  ERN  A  + R 
Sbjct: 200 NQAQVSPATQQMQPTQTIQPPQPTGG----RRRRVVDEDPDERRRKFLERNRAAATRCRQ 255

Query: 302 KAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLR 339
           K K   +  ++K  ELT  N +L+  V  L  E+  L+
Sbjct: 256 KRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLK 293


>gi|59938774 cAMP responsive element binding protein 5 isoform beta
           [Homo sapiens]
          Length = 501

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 44/158 (27%), Positives = 65/158 (41%), Gaps = 14/158 (8%)

Query: 186 PPPPSHPHPHPPPAHLAAP---HLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALG 242
           PP   +PH H  PAH   P   H Q    H   + +H  P H         SPHP    G
Sbjct: 278 PPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQT------SPHPPLHTG 331

Query: 243 AAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVR-RERNNIAVRKSRD 301
                 P +            + +GG    + ++ VD++ +E R +  ERN  A  + R 
Sbjct: 332 NQAQVSPATQQMQPTQTIQPPQPTGG----RRRRVVDEDPDERRRKFLERNRAAATRCRQ 387

Query: 302 KAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLR 339
           K K   +  ++K  ELT  N +L+  V  L  E+  L+
Sbjct: 388 KRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLK 425


>gi|59938772 cAMP responsive element binding protein 5 isoform gamma
           [Homo sapiens]
          Length = 475

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 44/158 (27%), Positives = 65/158 (41%), Gaps = 14/158 (8%)

Query: 186 PPPPSHPHPHPPPAHLAAP---HLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALG 242
           PP   +PH H  PAH   P   H Q    H   + +H  P H         SPHP    G
Sbjct: 252 PPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQT------SPHPPLHTG 305

Query: 243 AAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVR-RERNNIAVRKSRD 301
                 P +            + +GG    + ++ VD++ +E R +  ERN  A  + R 
Sbjct: 306 NQAQVSPATQQMQPTQTIQPPQPTGG----RRRRVVDEDPDERRRKFLERNRAAATRCRQ 361

Query: 302 KAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLR 339
           K K   +  ++K  ELT  N +L+  V  L  E+  L+
Sbjct: 362 KRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLK 399


>gi|59938770 cAMP responsive element binding protein 5 isoform alpha
           [Homo sapiens]
          Length = 508

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 44/158 (27%), Positives = 65/158 (41%), Gaps = 14/158 (8%)

Query: 186 PPPPSHPHPHPPPAHLAAP---HLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALG 242
           PP   +PH H  PAH   P   H Q    H   + +H  P H         SPHP    G
Sbjct: 285 PPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQT------SPHPPLHTG 338

Query: 243 AAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVR-RERNNIAVRKSRD 301
                 P +            + +GG    + ++ VD++ +E R +  ERN  A  + R 
Sbjct: 339 NQAQVSPATQQMQPTQTIQPPQPTGG----RRRRVVDEDPDERRRKFLERNRAAATRCRQ 394

Query: 302 KAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLR 339
           K K   +  ++K  ELT  N +L+  V  L  E+  L+
Sbjct: 395 KRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLK 432


>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 72/305 (23%), Positives = 101/305 (33%), Gaps = 68/305 (22%)

Query: 12  RPPMSSHLQSPPHAPSSAAFGFP---------RGAGPAQPPAPPAAPEPLGGICEHETSI 62
           RPP + + ++PP  P  A+   P          GA P  P  PPA   P      H++  
Sbjct: 387 RPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS-- 444

Query: 63  DISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDF------DYPGAP---- 112
                ++P       + D    ++      A  GP G  G G         +P AP    
Sbjct: 445 -----VEPVVMMHMNIQD--SGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVV 497

Query: 113 -----------AGPGGAVMPGGAHGPPPGYGCAAAGYLDGR-----LEPLYERVGAPALR 156
                      + PGG  + G   G   G   + A  + G      ++P+    G P + 
Sbjct: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557

Query: 157 P----LVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPH---------------PHPP 197
           P              + A     A   P QPPP P PS                  P   
Sbjct: 558 PPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAG 617

Query: 198 PAHLAAPHLQFQI----AHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSAL 253
            + +A+P +   +    A     T  LQ     PPP P P P P PA     +P PGS  
Sbjct: 618 GSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPP-PPPPPPPAPEQQTMPPPGSPS 676

Query: 254 KGLGA 258
            G G+
Sbjct: 677 GGAGS 681



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 69/259 (26%), Positives = 89/259 (34%), Gaps = 56/259 (21%)

Query: 32  GFPRGAGPAQPPAPPAA-PEPLGGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEK 90
           G P+      PP PPA  PEP+      +TS  + +   P    +   A+  +     + 
Sbjct: 187 GGPQPQHSQPPPQPPAVTPEPVA--LSSQTSEPVESEAPP---REPMEAEEVEERAPAQN 241

Query: 91  AKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYL---DGRLEPL- 146
            +   GP             APAGP  A      + P P         L   + RL+P  
Sbjct: 242 PELTPGP-------------APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFL 288

Query: 147 ---YERVGAPALRPLVIKQEPREEDE------AKQLALAG-LFPYQPP-----PPPPPSH 191
              YE +GA A        E REED+       + L L G  F             PP H
Sbjct: 289 QRYYEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRH 348

Query: 192 PHPHPPPAHLAAPHLQFQIAHCGQ----TTMHLQPGHPTPPPTP---VPSPHPAPALGAA 244
            H   P +H   P +  Q A   Q    TT+ +      PPPTP    P P P  A   A
Sbjct: 349 LHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVA 408

Query: 245 -----------GLPGPGSA 252
                      G P PG A
Sbjct: 409 PSSTNVESSAEGAPPPGPA 427



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 25/81 (30%), Positives = 29/81 (35%), Gaps = 7/81 (8%)

Query: 182 QPPPPPPPSHPHP------HPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSP 235
           QPPP PP   P P         P    AP  +   A   +     Q    TP P P   P
Sbjct: 195 QPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPA-GP 253

Query: 236 HPAPALGAAGLPGPGSALKGL 256
            PAP   A   P P   ++ L
Sbjct: 254 TPAPETNAPNHPSPAEYVEVL 274


>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 72/305 (23%), Positives = 101/305 (33%), Gaps = 68/305 (22%)

Query: 12  RPPMSSHLQSPPHAPSSAAFGFP---------RGAGPAQPPAPPAAPEPLGGICEHETSI 62
           RPP + + ++PP  P  A+   P          GA P  P  PPA   P      H++  
Sbjct: 387 RPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS-- 444

Query: 63  DISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDF------DYPGAP---- 112
                ++P       + D    ++      A  GP G  G G         +P AP    
Sbjct: 445 -----VEPVVMMHMNIQD--SGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVV 497

Query: 113 -----------AGPGGAVMPGGAHGPPPGYGCAAAGYLDGR-----LEPLYERVGAPALR 156
                      + PGG  + G   G   G   + A  + G      ++P+    G P + 
Sbjct: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557

Query: 157 P----LVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPH---------------PHPP 197
           P              + A     A   P QPPP P PS                  P   
Sbjct: 558 PPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAG 617

Query: 198 PAHLAAPHLQFQI----AHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSAL 253
            + +A+P +   +    A     T  LQ     PPP P P P P PA     +P PGS  
Sbjct: 618 GSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPP-PPPPPPPAPEQQTMPPPGSPS 676

Query: 254 KGLGA 258
            G G+
Sbjct: 677 GGAGS 681



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 69/259 (26%), Positives = 89/259 (34%), Gaps = 56/259 (21%)

Query: 32  GFPRGAGPAQPPAPPAA-PEPLGGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEK 90
           G P+      PP PPA  PEP+      +TS  + +   P    +   A+  +     + 
Sbjct: 187 GGPQPQHSQPPPQPPAVTPEPVA--LSSQTSEPVESEAPP---REPMEAEEVEERAPAQN 241

Query: 91  AKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYL---DGRLEPL- 146
            +   GP             APAGP  A      + P P         L   + RL+P  
Sbjct: 242 PELTPGP-------------APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFL 288

Query: 147 ---YERVGAPALRPLVIKQEPREEDE------AKQLALAG-LFPYQPP-----PPPPPSH 191
              YE +GA A        E REED+       + L L G  F             PP H
Sbjct: 289 QRYYEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRH 348

Query: 192 PHPHPPPAHLAAPHLQFQIAHCGQ----TTMHLQPGHPTPPPTP---VPSPHPAPALGAA 244
            H   P +H   P +  Q A   Q    TT+ +      PPPTP    P P P  A   A
Sbjct: 349 LHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVA 408

Query: 245 -----------GLPGPGSA 252
                      G P PG A
Sbjct: 409 PSSTNVESSAEGAPPPGPA 427



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 25/81 (30%), Positives = 29/81 (35%), Gaps = 7/81 (8%)

Query: 182 QPPPPPPPSHPHP------HPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSP 235
           QPPP PP   P P         P    AP  +   A   +     Q    TP P P   P
Sbjct: 195 QPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPA-GP 253

Query: 236 HPAPALGAAGLPGPGSALKGL 256
            PAP   A   P P   ++ L
Sbjct: 254 TPAPETNAPNHPSPAEYVEVL 274


>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 72/305 (23%), Positives = 101/305 (33%), Gaps = 68/305 (22%)

Query: 12  RPPMSSHLQSPPHAPSSAAFGFP---------RGAGPAQPPAPPAAPEPLGGICEHETSI 62
           RPP + + ++PP  P  A+   P          GA P  P  PPA   P      H++  
Sbjct: 387 RPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS-- 444

Query: 63  DISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDF------DYPGAP---- 112
                ++P       + D    ++      A  GP G  G G         +P AP    
Sbjct: 445 -----VEPVVMMHMNIQD--SGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVV 497

Query: 113 -----------AGPGGAVMPGGAHGPPPGYGCAAAGYLDGR-----LEPLYERVGAPALR 156
                      + PGG  + G   G   G   + A  + G      ++P+    G P + 
Sbjct: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557

Query: 157 P----LVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPH---------------PHPP 197
           P              + A     A   P QPPP P PS                  P   
Sbjct: 558 PPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAG 617

Query: 198 PAHLAAPHLQFQI----AHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSAL 253
            + +A+P +   +    A     T  LQ     PPP P P P P PA     +P PGS  
Sbjct: 618 GSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPP-PPPPPPPAPEQQTMPPPGSPS 676

Query: 254 KGLGA 258
            G G+
Sbjct: 677 GGAGS 681



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 69/259 (26%), Positives = 89/259 (34%), Gaps = 56/259 (21%)

Query: 32  GFPRGAGPAQPPAPPAA-PEPLGGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEK 90
           G P+      PP PPA  PEP+      +TS  + +   P    +   A+  +     + 
Sbjct: 187 GGPQPQHSQPPPQPPAVTPEPVA--LSSQTSEPVESEAPP---REPMEAEEVEERAPAQN 241

Query: 91  AKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYL---DGRLEPL- 146
            +   GP             APAGP  A      + P P         L   + RL+P  
Sbjct: 242 PELTPGP-------------APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFL 288

Query: 147 ---YERVGAPALRPLVIKQEPREEDE------AKQLALAG-LFPYQPP-----PPPPPSH 191
              YE +GA A        E REED+       + L L G  F             PP H
Sbjct: 289 QRYYEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRH 348

Query: 192 PHPHPPPAHLAAPHLQFQIAHCGQ----TTMHLQPGHPTPPPTP---VPSPHPAPALGAA 244
            H   P +H   P +  Q A   Q    TT+ +      PPPTP    P P P  A   A
Sbjct: 349 LHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVA 408

Query: 245 -----------GLPGPGSA 252
                      G P PG A
Sbjct: 409 PSSTNVESSAEGAPPPGPA 427



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 25/81 (30%), Positives = 29/81 (35%), Gaps = 7/81 (8%)

Query: 182 QPPPPPPPSHPHP------HPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSP 235
           QPPP PP   P P         P    AP  +   A   +     Q    TP P P   P
Sbjct: 195 QPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPA-GP 253

Query: 236 HPAPALGAAGLPGPGSALKGL 256
            PAP   A   P P   ++ L
Sbjct: 254 TPAPETNAPNHPSPAEYVEVL 274


>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
          Length = 1132

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 72/305 (23%), Positives = 101/305 (33%), Gaps = 68/305 (22%)

Query: 12  RPPMSSHLQSPPHAPSSAAFGFP---------RGAGPAQPPAPPAAPEPLGGICEHETSI 62
           RPP + + ++PP  P  A+   P          GA P  P  PPA   P      H++  
Sbjct: 393 RPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS-- 450

Query: 63  DISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDF------DYPGAP---- 112
                ++P       + D    ++      A  GP G  G G         +P AP    
Sbjct: 451 -----VEPVVMMHMNIQD--SGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVV 503

Query: 113 -----------AGPGGAVMPGGAHGPPPGYGCAAAGYLDGR-----LEPLYERVGAPALR 156
                      + PGG  + G   G   G   + A  + G      ++P+    G P + 
Sbjct: 504 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 563

Query: 157 P----LVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPH---------------PHPP 197
           P              + A     A   P QPPP P PS                  P   
Sbjct: 564 PPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAG 623

Query: 198 PAHLAAPHLQFQI----AHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSAL 253
            + +A+P +   +    A     T  LQ     PPP P P P P PA     +P PGS  
Sbjct: 624 GSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPP-PPPPPPPAPEQQTMPPPGSPS 682

Query: 254 KGLGA 258
            G G+
Sbjct: 683 GGAGS 687



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 69/259 (26%), Positives = 89/259 (34%), Gaps = 56/259 (21%)

Query: 32  GFPRGAGPAQPPAPPAA-PEPLGGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEK 90
           G P+      PP PPA  PEP+      +TS  + +   P    +   A+  +     + 
Sbjct: 193 GGPQPQHSQPPPQPPAVTPEPVA--LSSQTSEPVESEAPP---REPMEAEEVEERAPAQN 247

Query: 91  AKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYL---DGRLEPL- 146
            +   GP             APAGP  A      + P P         L   + RL+P  
Sbjct: 248 PELTPGP-------------APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFL 294

Query: 147 ---YERVGAPALRPLVIKQEPREEDE------AKQLALAG-LFPYQPP-----PPPPPSH 191
              YE +GA A        E REED+       + L L G  F             PP H
Sbjct: 295 QRYYEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRH 354

Query: 192 PHPHPPPAHLAAPHLQFQIAHCGQ----TTMHLQPGHPTPPPTP---VPSPHPAPALGAA 244
            H   P +H   P +  Q A   Q    TT+ +      PPPTP    P P P  A   A
Sbjct: 355 LHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVA 414

Query: 245 -----------GLPGPGSA 252
                      G P PG A
Sbjct: 415 PSSTNVESSAEGAPPPGPA 433



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 25/81 (30%), Positives = 29/81 (35%), Gaps = 7/81 (8%)

Query: 182 QPPPPPPPSHPHP------HPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSP 235
           QPPP PP   P P         P    AP  +   A   +     Q    TP P P   P
Sbjct: 201 QPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAPA-GP 259

Query: 236 HPAPALGAAGLPGPGSALKGL 256
            PAP   A   P P   ++ L
Sbjct: 260 TPAPETNAPNHPSPAEYVEVL 280


>gi|205277421 Jun dimerization protein 2 isoform b [Homo sapiens]
          Length = 174

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 20/136 (14%)

Query: 223 GHPTPPPTPVPSPHPAPALGAAGLPG-------PGSALKGLGAAHPDLRASG-------- 267
           G P  PP  +P   P P++    LPG       P SAL      + D+R  G        
Sbjct: 4   GWPATPPAMMPGQIPDPSVTTGSLPGLGPLTGLPSSALTVEELKYADIRNLGAMIAPLHF 63

Query: 268 -----GSGAGKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDND 322
                G      K  +D+     + RRE+N +A  + R+K K+R    Q++   L   N 
Sbjct: 64  LEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNA 123

Query: 323 RLRKRVEQLSRELDTL 338
            L+ ++E+L +E   L
Sbjct: 124 ELKTQIEELKQERQQL 139


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 32/89 (35%), Positives = 37/89 (41%), Gaps = 19/89 (21%)

Query: 183  PPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGH-----------PTPPPTP 231
            PPPPPPP  P PH         H Q  +AH       + PG            P PPP P
Sbjct: 1627 PPPPPPPPAPGPH--LVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPP 1684

Query: 232  VPSPHPAPALGAAGLPGPGSALKGLGAAH 260
             P+PH  P       P P + L+GL A H
Sbjct: 1685 GPAPHHHPP------PHPSTGLQGLQAQH 1707



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 24/53 (45%), Positives = 26/53 (49%), Gaps = 7/53 (13%)

Query: 183  PPPPPPPS-HPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPS 234
            PPPPPPP   PH HPPP H +      Q  H      H+    P PPP P PS
Sbjct: 1678 PPPPPPPGPAPHHHPPP-HPSTGLQGLQAQH-----QHVVNSAPPPPPPPPPS 1724



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 51/192 (26%), Positives = 57/192 (29%), Gaps = 71/192 (36%)

Query: 114  GPGGAVMPG--------GAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPR 165
            GP  AV PG        G H PPP       G       P +   G   L          
Sbjct: 1657 GPVHAVTPGSHIHSQTAGHHLPPPP---PPPGPAPHHHPPPHPSTGLQGL---------- 1703

Query: 166  EEDEAKQLALAGLFPYQPPPPPPPS--------------HPHPH------PPPAHLAAPH 205
               +A+   +    P  PPPPPP S              H  PH      P  AH   P 
Sbjct: 1704 ---QAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPP 1760

Query: 206  LQFQIAHCGQTTM----------------------HLQPGHPTPPPTPVPS---PHPAPA 240
               Q  H   TT+                      HLQP  P   PTP  S   PHP   
Sbjct: 1761 YPSQATH--HTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSV 1818

Query: 241  LGAAGLPGPGSA 252
                G+ GP  A
Sbjct: 1819 ALPHGVQGPQQA 1830



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 26/104 (25%), Positives = 34/104 (32%), Gaps = 39/104 (37%)

Query: 172  QLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTM------------- 218
            Q +L    P  PPPPPP S  + +  P+     + Q + +   QT               
Sbjct: 1536 QQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTS 1595

Query: 219  -------HLQPGH-------------------PTPPPTPVPSPH 236
                   H+ PGH                   P PPP P P PH
Sbjct: 1596 QQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPH 1639



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 35/122 (28%), Positives = 44/122 (36%), Gaps = 7/122 (5%)

Query: 11   PRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPP--APPAAPEPLGGICEHETSIDISAYI 68
            P PP SS L S  H  S+ A   P   GP   P  A P  P P      H T++      
Sbjct: 1719 PPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVP-PYPSQATHHTTLGPGPQH 1777

Query: 69   DPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPP 128
             P+         +     Q +   +   PT     G   +PG+ A P G   P  A  P 
Sbjct: 1778 QPSGTGPHCPLPVTGPHLQPQGPNSIPTPT---ASGFCPHPGSVALPHGVQGPQQA-SPV 1833

Query: 129  PG 130
            PG
Sbjct: 1834 PG 1835


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 66/252 (26%), Positives = 78/252 (30%), Gaps = 48/252 (19%)

Query: 12  RPPMSSHLQSPPHAPSSAAFG------------FPRGAGPAQP--PAPPAAPEPLGGICE 57
           RPP S      P  P     G             PR A PA+   PAP    E +     
Sbjct: 426 RPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQH 485

Query: 58  HETSIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTG-----GGGGGDFDYPGAP 112
                 I   +        FLA   +   +          TG     G G G    P AP
Sbjct: 486 SSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAP 545

Query: 113 AG-----PGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREE 167
           A      P G+  PG     P   G   A       +                  E  ++
Sbjct: 546 ANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDD-----------------MEISDD 588

Query: 168 DEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTP 227
           D       A   P QPPPPPPP    P PPP +LA+  L +   H  Q    L P    P
Sbjct: 589 DRGGSPPPAPTPPQQPPPPPPP----PPPPPPYLASLPLGYP-PH--QPAYLLPPRPDGP 641

Query: 228 PPTPVPSPHPAP 239
           PP   P P P P
Sbjct: 642 PPPEYPPPPPPP 653



 Score = 32.3 bits (72), Expect = 0.67
 Identities = 31/112 (27%), Positives = 41/112 (36%), Gaps = 27/112 (24%)

Query: 145  PLYERVGAPALRPLVIKQE-------PREEDEAKQLALAGLFPYQPPPPPP--------- 188
            P+ ERV    + PL  ++        P EE        A L P +PP  PP         
Sbjct: 1095 PVPERVAGSPVTPLPEQEASPARPAGPTEESPPS----APLRPPEPPAGPPAPAPRPDER 1150

Query: 189  PSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPA 240
            PS P P  PP       + F       + + + P    PP TP  +  P PA
Sbjct: 1151 PSSPIPLLPPPKKRRKTVSF-------SAIEVVPAPEPPPATPPQAKFPGPA 1195



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 29/103 (28%), Positives = 34/103 (33%), Gaps = 16/103 (15%)

Query: 163  EPREEDEAKQLALAGLFPYQPPP---PPPPSHPHPHPPPAHLAA------PHLQFQIAHC 213
            E   EDE ++   A L    PPP   P P   P   P P  +A       P  +   A  
Sbjct: 1059 ESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARP 1118

Query: 214  GQTTMHLQPGHP-------TPPPTPVPSPHPAPALGAAGLPGP 249
               T    P  P         PP P P P   P+     LP P
Sbjct: 1119 AGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPP 1161



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 10/44 (22%)

Query: 8    EAEPRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEP 51
            EA P  P     +SPP AP            P +PPA P AP P
Sbjct: 1112 EASPARPAGPTEESPPSAPLR----------PPEPPAGPPAPAP 1145



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 50/189 (26%), Positives = 66/189 (34%), Gaps = 44/189 (23%)

Query: 97  PTGGGGGG-------DFDYPGAPAGPG--GAVMPGGAHGPPPGYGCAAAGYLDGRLEPLY 147
           P GGGGGG       +      PA P   G+  P   +   P    A    LD R+E L 
Sbjct: 440 PGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVP---FAQHSSLDSRIEMLL 496

Query: 148 ERVGAPALRPLVIKQEPREEDEAKQLAL------------AGLFPYQPPPPPPP----SH 191
           +   +   +   +  +  EE+E   + L            +G  P  PPP P      + 
Sbjct: 497 KEQRS---KFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAP 553

Query: 192 PHPHPPPAHLAAPHL--QFQIAHCGQ-TTMHLQ--------PGHPTPP--PTPVPSPHPA 238
                P A   +P    Q Q + C     M +         P  PTPP  P P P P P 
Sbjct: 554 TGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPP 613

Query: 239 PALGAAGLP 247
           P    A LP
Sbjct: 614 PPPYLASLP 622



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 11/33 (33%), Positives = 17/33 (51%)

Query: 182  QPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCG 214
            +PPPPPPP  P  + P +      + + I + G
Sbjct: 1402 RPPPPPPPPPPRAYEPRSEFEQMTILYDIWNSG 1434


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 32/89 (35%), Positives = 37/89 (41%), Gaps = 19/89 (21%)

Query: 183  PPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGH-----------PTPPPTP 231
            PPPPPPP  P PH         H Q  +AH       + PG            P PPP P
Sbjct: 1627 PPPPPPPPAPGPH--LVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPP 1684

Query: 232  VPSPHPAPALGAAGLPGPGSALKGLGAAH 260
             P+PH  P       P P + L+GL A H
Sbjct: 1685 GPAPHHHPP------PHPSTGLQGLQAQH 1707



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 24/53 (45%), Positives = 26/53 (49%), Gaps = 7/53 (13%)

Query: 183  PPPPPPPS-HPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPS 234
            PPPPPPP   PH HPPP H +      Q  H      H+    P PPP P PS
Sbjct: 1678 PPPPPPPGPAPHHHPPP-HPSTGLQGLQAQH-----QHVVNSAPPPPPPPPPS 1724



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 51/192 (26%), Positives = 57/192 (29%), Gaps = 71/192 (36%)

Query: 114  GPGGAVMPG--------GAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPR 165
            GP  AV PG        G H PPP       G       P +   G   L          
Sbjct: 1657 GPVHAVTPGSHIHSQTAGHHLPPPP---PPPGPAPHHHPPPHPSTGLQGL---------- 1703

Query: 166  EEDEAKQLALAGLFPYQPPPPPPPS--------------HPHPH------PPPAHLAAPH 205
               +A+   +    P  PPPPPP S              H  PH      P  AH   P 
Sbjct: 1704 ---QAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPP 1760

Query: 206  LQFQIAHCGQTTM----------------------HLQPGHPTPPPTPVPS---PHPAPA 240
               Q  H   TT+                      HLQP  P   PTP  S   PHP   
Sbjct: 1761 YPSQATH--HTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSV 1818

Query: 241  LGAAGLPGPGSA 252
                G+ GP  A
Sbjct: 1819 ALPHGVQGPQQA 1830



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 26/104 (25%), Positives = 34/104 (32%), Gaps = 39/104 (37%)

Query: 172  QLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTM------------- 218
            Q +L    P  PPPPPP S  + +  P+     + Q + +   QT               
Sbjct: 1536 QQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTS 1595

Query: 219  -------HLQPGH-------------------PTPPPTPVPSPH 236
                   H+ PGH                   P PPP P P PH
Sbjct: 1596 QQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPH 1639



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 35/122 (28%), Positives = 44/122 (36%), Gaps = 7/122 (5%)

Query: 11   PRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPP--APPAAPEPLGGICEHETSIDISAYI 68
            P PP SS L S  H  S+ A   P   GP   P  A P  P P      H T++      
Sbjct: 1719 PPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVP-PYPSQATHHTTLGPGPQH 1777

Query: 69   DPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPP 128
             P+         +     Q +   +   PT     G   +PG+ A P G   P  A  P 
Sbjct: 1778 QPSGTGPHCPLPVTGPHLQPQGPNSIPTPT---ASGFCPHPGSVALPHGVQGPQQA-SPV 1833

Query: 129  PG 130
            PG
Sbjct: 1834 PG 1835


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 72/261 (27%), Positives = 96/261 (36%), Gaps = 59/261 (22%)

Query: 11  PRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAY--I 68
           P PP       PP  P     G P       PP PP+AP           S D S+    
Sbjct: 5   PPPP-------PPLPPPPPPLGAP-------PPPPPSAPP---------VSTDTSSLRRA 41

Query: 69  DPAAFNDEFLADLFQHSRQQE----------KAKAAVGPTGGGGGGDFDYPGAPAGPG-G 117
           DP       LAD+ Q +R ++          + +++ G T   GGG  +  GA   P  G
Sbjct: 42  DPKG-RSALLADIQQGTRLRKVTQINDRSAPQIESSKG-TNKEGGGSANTRGASTPPTLG 99

Query: 118 AVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALR------PLVIKQEPREEDEAK 171
            +  GG     P      AG   G+      R  +P L       PL+    PR  + ++
Sbjct: 100 DLFAGGFPVLRPAGQRDVAGGKTGQGPG--SRAPSPRLPNKTISGPLIPPASPRLGNTSE 157

Query: 172 QLALAGLFPYQP-----PPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQP---- 222
               A   P +P     PPP PP  P P PPP   ++P     ++  G  T    P    
Sbjct: 158 AHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP 217

Query: 223 ----GHPTPPPTPVPSPHPAP 239
                 P PPP P P+P P P
Sbjct: 218 PVPCAPPPPPPPPPPTPPPLP 238



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 34/118 (28%), Positives = 44/118 (37%), Gaps = 20/118 (16%)

Query: 152 APALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIA 211
           +P   PLV    P  +     +A        PPPPPPP  P P PP + L+   ++ Q+A
Sbjct: 194 SPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLA 253

Query: 212 ---------------HCGQTTMHLQPGHPT-----PPPTPVPSPHPAPALGAAGLPGP 249
                           CG   +  +P  P      PP  P P P  A     A LP P
Sbjct: 254 PLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAP 311



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 14/27 (51%), Positives = 15/27 (55%)

Query: 225 PTPPPTPVPSPHPAPALGAAGLPGPGS 251
           P PPP P P P P P LGA   P P +
Sbjct: 2   PVPPPPPPPLPPPPPPLGAPPPPPPSA 28



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 60/257 (23%), Positives = 70/257 (27%), Gaps = 46/257 (17%)

Query: 13  PPMSSHLQSPPHAPSSAAFGFPRGAGPAQPP-APPAAPEPLGGICEHETSIDISAYIDPA 71
           PP S  L +   A  +A    PR   PA PP  PP  P PL       + I       P 
Sbjct: 146 PPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPG 205

Query: 72  AFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPP-PG 130
                                         G      P  P  P     P     PP P 
Sbjct: 206 PLTK--------------------------GNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239

Query: 131 YGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPP- 189
               +   +  +L PL+     P L  L     P  + E    A     P  PPPP PP 
Sbjct: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPY 299

Query: 190 -------SHPHPH----------PPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPV 232
                  S P P           PPP    +P  Q      G   +   P  P   P   
Sbjct: 300 ASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQ 359

Query: 233 PSPHPAPALGAAGLPGP 249
              H  P  G   L  P
Sbjct: 360 KKRHGRPGAGGGKLNPP 376



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 14/26 (53%), Positives = 15/26 (57%), Gaps = 4/26 (15%)

Query: 183 PPPPPPPSHPHP----HPPPAHLAAP 204
           PPPPPPP  P P     PPP   +AP
Sbjct: 4   PPPPPPPLPPPPPPLGAPPPPPPSAP 29



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 21/70 (30%)

Query: 184 PPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGA 243
           P PPPP  P P PPP  L AP                    P PPP+  P      +L  
Sbjct: 2   PVPPPPPPPLP-PPPPPLGAP--------------------PPPPPSAPPVSTDTSSLRR 40

Query: 244 AGLPGPGSAL 253
           A   G  + L
Sbjct: 41  ADPKGRSALL 50



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 5/44 (11%)

Query: 11  PRPPM----SSHLQSPPHAPSSAAF-GFPRGAGPAQPPAPPAAP 49
           P PP+    SS    PP  P S +F   P+ AG    PAPPA P
Sbjct: 309 PAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPP 352


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.135    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,309,098
Number of Sequences: 37866
Number of extensions: 1774277
Number of successful extensions: 40336
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 714
Number of HSP's successfully gapped in prelim test: 1422
Number of HSP's that attempted gapping in prelim test: 14947
Number of HSP's gapped (non-prelim): 14203
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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