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Search of human proteins with 28559039
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28559039 mediator complex subunit 1 [Homo sapiens]
(1581 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28559039 mediator complex subunit 1 [Homo sapiens] 3159 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 151 4e-36
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 109 2e-23
gi|57864582 hornerin [Homo sapiens] 104 8e-22
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 100 1e-20
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 90 2e-17
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 87 1e-16
gi|161016767 mucin 21 [Homo sapiens] 87 1e-16
gi|60097902 filaggrin [Homo sapiens] 86 3e-16
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 85 5e-16
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 84 8e-16
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 81 9e-15
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 77 1e-13
gi|62122917 filaggrin family member 2 [Homo sapiens] 76 2e-13
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 76 2e-13
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 75 5e-13
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 74 1e-12
gi|50083281 KIAA1853 protein [Homo sapiens] 72 3e-12
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 72 4e-12
gi|118572603 ubinuclein 1 [Homo sapiens] 72 6e-12
gi|118572601 ubinuclein 1 [Homo sapiens] 72 6e-12
gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens] 71 7e-12
gi|120953251 neuron navigator 3 [Homo sapiens] 71 7e-12
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 71 9e-12
gi|91982772 mucin 17 [Homo sapiens] 70 1e-11
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 70 2e-11
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] 70 2e-11
gi|89026265 PREDICTED: mucin 12 [Homo sapiens] 70 2e-11
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 70 2e-11
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 69 4e-11
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 3159 bits (8191), Expect = 0.0
Identities = 1581/1581 (100%), Positives = 1581/1581 (100%)
Query: 1 MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVS 60
MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVS
Sbjct: 1 MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVS 60
Query: 61 CLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQL 120
CLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQL
Sbjct: 61 CLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQL 120
Query: 121 CDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL 180
CDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL
Sbjct: 121 CDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL 180
Query: 181 EQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGGHLMNLKYYVSPSDLLDDKTASPI 240
EQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGGHLMNLKYYVSPSDLLDDKTASPI
Sbjct: 181 EQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGGHLMNLKYYVSPSDLLDDKTASPI 240
Query: 241 ILHENNVSRSLGMNASVTIEGTSAVYKLPIAPLIMGSHPVDNKWTPSFSSITSANSVDLP 300
ILHENNVSRSLGMNASVTIEGTSAVYKLPIAPLIMGSHPVDNKWTPSFSSITSANSVDLP
Sbjct: 241 ILHENNVSRSLGMNASVTIEGTSAVYKLPIAPLIMGSHPVDNKWTPSFSSITSANSVDLP 300
Query: 301 ACFFLKFPQPIPVSRAFVQKLQNCTGIPLFETQPTYAPLYELITQFELSKDPDPIPLNHN 360
ACFFLKFPQPIPVSRAFVQKLQNCTGIPLFETQPTYAPLYELITQFELSKDPDPIPLNHN
Sbjct: 301 ACFFLKFPQPIPVSRAFVQKLQNCTGIPLFETQPTYAPLYELITQFELSKDPDPIPLNHN 360
Query: 361 MRFYAALPGQQHCYFLNKDAPLPDGRSLQGTLVSKITFQHPGRVPLILNLIRHQVAYNTL 420
MRFYAALPGQQHCYFLNKDAPLPDGRSLQGTLVSKITFQHPGRVPLILNLIRHQVAYNTL
Sbjct: 361 MRFYAALPGQQHCYFLNKDAPLPDGRSLQGTLVSKITFQHPGRVPLILNLIRHQVAYNTL 420
Query: 421 IGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLY 480
IGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLY
Sbjct: 421 IGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLY 480
Query: 481 KGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNL 540
KGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNL
Sbjct: 481 KGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNL 540
Query: 541 PPASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQ 600
PPASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQ
Sbjct: 541 PPASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQ 600
Query: 601 NPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTL 660
NPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTL
Sbjct: 601 NPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTL 660
Query: 661 YGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQ 720
YGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQ
Sbjct: 661 YGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQ 720
Query: 721 NPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVT 780
NPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVT
Sbjct: 721 NPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVT 780
Query: 781 DILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPAD 840
DILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPAD
Sbjct: 781 DILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPAD 840
Query: 841 LIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFAS 900
LIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFAS
Sbjct: 841 LIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFAS 900
Query: 901 QALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTT 960
QALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTT
Sbjct: 901 QALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTT 960
Query: 961 GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGK 1020
GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGK
Sbjct: 961 GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGK 1020
Query: 1021 SPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSH 1080
SPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSH
Sbjct: 1021 SPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSH 1080
Query: 1081 SQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGS 1140
SQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGS
Sbjct: 1081 SQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGS 1140
Query: 1141 SQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG 1200
SQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG
Sbjct: 1141 SQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG 1200
Query: 1201 GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP 1260
GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP
Sbjct: 1201 GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP 1260
Query: 1261 PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPG 1320
PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPG
Sbjct: 1261 PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPG 1320
Query: 1321 GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE 1380
GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE
Sbjct: 1321 GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE 1380
Query: 1381 SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGST 1440
SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGST
Sbjct: 1381 SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGST 1440
Query: 1441 PKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500
PKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH
Sbjct: 1441 PKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500
Query: 1501 KKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRL 1560
KKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRL
Sbjct: 1501 KKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRL 1560
Query: 1561 SPDFMIGEEDDDLMDVALIGN 1581
SPDFMIGEEDDDLMDVALIGN
Sbjct: 1561 SPDFMIGEEDDDLMDVALIGN 1581
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 151 bits (382), Expect = 4e-36
Identities = 176/758 (23%), Positives = 283/758 (37%), Gaps = 41/758 (5%)
Query: 770 SSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTN 829
S SDS D +D + ++S +SD + DSS S S + DS +++
Sbjct: 578 SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDS-----SDSSDSSDSSDSKSDSSKSESD 632
Query: 830 NNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQS 889
++++ D +D++ S SSDS N D + + +S S +SS S
Sbjct: 633 SSDS------DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686
Query: 890 GDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEH 949
D+ D ++ + ++ D+ ++ N+ + D S S + + +D +
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746
Query: 950 HSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKP 1009
S + D + + +S+S+ S DS S S+ S D
Sbjct: 747 SDSSNSS--DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 1010 PKRKKADTEGKSPSHSSSNRPFTPPT-STGGSKSPGSAGRSQTPPGVATPPIPKITIQIP 1068
+D+ S S SS++ + + S+ S S S+ S + G +
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD-------SSN 857
Query: 1069 KGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLS 1128
+ SS S +S+ S SS S S+ S +SS SS +S S SS S SS S S
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS 917
Query: 1129 SSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSK 1188
S+ S SS SS + NSS S SS + SS SS++ SS N S S
Sbjct: 918 SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977
Query: 1189 PNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSG 1248
+ + S S S + + S + S SS S S S SS+S S S
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 1249 LGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVID 1308
S S S + SS+S +S SS SS S S S + SS S + S ++ D
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS--D 1095
Query: 1309 KLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTS 1368
+ D D +++SS S + + + SD +S S+
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155
Query: 1369 GSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASS 1428
S S +S+S + + + D S S SS
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS----------DSSDSSDSSDSSDSS 1205
Query: 1429 KNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRP 1488
+ S S S+ + S S + + DS S SS + S +S SSD
Sbjct: 1206 DSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS---- 1261
Query: 1489 LPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSH 1526
+++ + + + K + D D D + S+
Sbjct: 1262 ----TSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295
Score = 147 bits (372), Expect = 6e-35
Identities = 168/723 (23%), Positives = 261/723 (36%), Gaps = 17/723 (2%)
Query: 771 SSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNN 830
SSDS D +D + S S S D DSS S S S+ DS +++
Sbjct: 587 SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS-ESDSSDSDSKSDSSDS 645
Query: 831 NENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSG 890
N + +D +D + S SSDS + D + +S S ESS S
Sbjct: 646 NSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS 705
Query: 891 DNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHH 950
D+ D S + N +N +D+ D S S + + +D
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765
Query: 951 SGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPP 1010
S + D + N +SNS+ S +S S S+ S D
Sbjct: 766 DSSD-----SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDS 820
Query: 1011 KRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKG 1070
+ S SS++ + + + S+ RS + + +
Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880
Query: 1071 TVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSS 1130
SS+S +S S SS S S+SS SS S+++S +SS S +S+S SS+
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 1131 MYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPN 1190
S SS SS S +SS S SS + S S S+ S + S S +
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 1191 ISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLG 1250
+ S S S ++ + S+ + S SS S S S SS S S+S
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 1251 SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL 1310
S S S + SS+S +S SS SS S S+S + SS S + S ++ D
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS--DSS 1118
Query: 1311 KHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGS 1370
+ D D +++ SS S + + + SD S S+ S
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 1371 SVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKN 1430
+ S +S+S + + + D S + + S + +S +
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Query: 1431 YGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGS---------SIAEKSYQNSPS 1481
S S S S S + + DS+S+SG+ S +E S N +
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298
Query: 1482 SDD 1484
SDD
Sbjct: 1299 SDD 1301
Score = 144 bits (363), Expect = 7e-34
Identities = 189/786 (24%), Positives = 289/786 (36%), Gaps = 59/786 (7%)
Query: 770 SSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQS---TLFDSDVF 826
S S+S G D D D P++SD+ + G +S S +S S ++SD
Sbjct: 443 SDSNSDGYDSYDF--DDKSMQGDDPNSSDE--SNGNDDANSESDNNSSSRGDASYNSDES 498
Query: 827 QTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDES 886
+ N N + D +D+ S +++S +N ++G D N + + +S + +S
Sbjct: 499 KDNGNGSDSKGAEDDDSDST-SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557
Query: 887 SQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADL 946
S S D+ D S N+ D+ ++ ++ +D+ D S S + + +D
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSS----DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613
Query: 947 MEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSK 1006
+ S S + + + K + SNS+ S DS S S+ S
Sbjct: 614 SDS-SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672
Query: 1007 DKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQ 1066
D +D+ S S SS+ S+ S+S S+ S +
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSD-------SSNSSESSDSSDSSDSDSS------------ 713
Query: 1067 IPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSK 1126
S S+ S S S + S S SS+SS S+ +S SS S SS S
Sbjct: 714 -----------DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762
Query: 1127 LSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSL 1186
SS S SS SS S NSS S SS + SS SS++ SS + S
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822
Query: 1187 SKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSS 1246
S + + S S S + G+ S +S S+ S S S +S+SS S
Sbjct: 823 SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Query: 1247 SGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAV 1306
S S + S + S++S + SS S +SS SS SS+ + S S + N S +
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Query: 1307 --IDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSK 1364
D + D + +NSS SS + S D S
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 1365 VSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQ 1424
S S S DSS ++ S + S S S S + + S
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNS--------SDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1054
Query: 1425 MASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDD 1484
SS + S S S+ + S S + + + +S S SS + S +S SSD
Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114
Query: 1485 GIRPLPEYSTEKHKKHKKEKKKVKD-KDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQS 1543
+ S + + D D D + S S S S SSD S
Sbjct: 1115 S-----DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 1544 LSMTSN 1549
S S+
Sbjct: 1170 DSSDSS 1175
Score = 140 bits (352), Expect = 1e-32
Identities = 185/749 (24%), Positives = 285/749 (38%), Gaps = 68/749 (9%)
Query: 647 NLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTED 706
N D+ + D S SS + +SS+ S + S+ + SS + K +++
Sbjct: 575 NSSSDSDSSD-SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD- 632
Query: 707 DFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRM 766
S D DS++ D N ++D+ D + + + ++ ++ S
Sbjct: 633 -------SSDSDSKSDSSDSN-SSDSSDNSDSSDSSNSSNSSDSS---------DSSDSS 675
Query: 767 VRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVF 826
SSSDS + SD +S +SD + + DSS S +S S+ DS
Sbjct: 676 DSSSSSDSSNSSDSSDSSD----SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 827 QTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDES 886
+++ + +D +D + S SSDS + D D + +S S + S
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791
Query: 887 SQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADL 946
S S D+ + ++ + ++ D+ + +N +D+ D S S + + +D
Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS-DSSNSSDSSDSSNSSDSSDSSDSSDG 850
Query: 947 MEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSK 1006
+ S ++ + D + + +S+S S DS S+D S
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN----SSDSDSS 906
Query: 1007 DKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQ 1066
D +D+ S S SSN S+ S S S+ S +
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSN-------SSDNSNSSDSSNSSDSSD------------- 946
Query: 1067 IPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSK 1126
SS+S +S+ S SS+ S S S+SS SS S+++S SS S SS S
Sbjct: 947 --------SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 1127 LSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSS-STKMKPQGKPSSLMNPS 1185
SS+ S SS SS S NSS S SS + SS SS S+ S N S
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 1186 LSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKS 1245
S + S S S + + + S+ + S SS S S S SS S S
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 1246 SSGLGSSGSLSQKTPPSSNSCTASSSSFS--------SSGSSMSSSQNQHGSSKGKSPSR 1297
S S S S + SS+S +S SS S SS SS SS + S S S
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 1298 NKKPSLTA--VIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKR 1355
N S + D + D D ++ SS S + E
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Query: 1356 EKSD-KDKSKVSTSGSSVDSSKKTSESKN 1383
+ SD D S S S S DSS TS+S +
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267
Score = 134 bits (337), Expect = 7e-31
Identities = 184/772 (23%), Positives = 261/772 (33%), Gaps = 51/772 (6%)
Query: 814 GHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVD-FNPDLLNS 872
G Q + + V +N + +D D S D P + +G D N + N+
Sbjct: 425 GPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNN 484
Query: 873 QSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFS 932
S G DES +G+ D KG ++ +N ++ GNN D D S
Sbjct: 485 SSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTS----DTNNSDSNGNGNNGNDDNDKS 540
Query: 933 IISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKP 992
+ +D + + S + + + N +S+S S
Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDS---------SDSSDSDSSDSNSSSDSDSSDSDSSDSS 591
Query: 993 GKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTP 1052
S SN S D +D+ S S S S++ + +S SKS S S
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD-SSDSDSKSDSSDSNSSDS 650
Query: 1053 PGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSG 1112
S +S + S + S+S S S SS SSSS+ +S
Sbjct: 651 -------------------------SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 1113 KMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKM 1172
SS S SS+S SS S S S S +S+ + SS + SS SS +
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 1173 KPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGS 1232
SS + S N S S S SD S +S S S+ S S
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDS-SDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 1233 HMSGTSSSSGMKSSSGLGSS-GSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGS-- 1289
+ S +S SS S SS S S + SSNS +S SS SS GS SS S
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 1290 --SKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMS 1347
S S S N S + D + + + D S+NSS SS + S
Sbjct: 865 SDSSDSSDSSNSSDSSDS-SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923
Query: 1348 GGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAK 1407
+ D S S S S DSS + S + S+ + S S S +
Sbjct: 924 SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 1408 VTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESES 1467
+ S SS + S S S+ + + S S + + + + DS S
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043
Query: 1468 GSSIAEKSYQNSPSSDDG----IRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKK 1523
SS + S +S SSD + S E D D D
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 1524 KSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRLSPDFMIGEEDDDLMD 1575
S S S S S + ++ S S S D E D D
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155
Score = 99.4 bits (246), Expect = 2e-20
Identities = 167/748 (22%), Positives = 256/748 (34%), Gaps = 84/748 (11%)
Query: 884 DESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAP 943
D+++Q+GD D A+ P + G N T +N+ + ++ S + +
Sbjct: 159 DKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNST----DNEDEIIENSCRNEGNTSEIT 214
Query: 944 ADLMEHHSGSQGPLLTTG---DLGKEKTQ---------KRVKEGNGTSNSTLSGPGLDSK 991
+ +G++ +T G D G + + + EG+G +G G DS
Sbjct: 215 PQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSS 274
Query: 992 PGKRSRTPSNDGKSKD-------KPPKRKKADTEGKSPSHSSSNRPFTPPT---STGGSK 1041
+ + + GK D ++ D EGK H+ + T + S G +
Sbjct: 275 NNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPE 334
Query: 1042 SPGS-----------------------------AGRSQTPPGVATPPIP---KITIQIPK 1069
GS G+SQ P IT ++ K
Sbjct: 335 DNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGK 394
Query: 1070 GT----------VMVGKPSSHSQ-----YTSSGSVSSSGSKSHHSHSSSSSSSASTSGKM 1114
G +++GK + +Q G S G+K HS++ S S+S
Sbjct: 395 GNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYD 454
Query: 1115 KSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKP 1174
KS +SS S+ +S+S N+S S G + +GS S +
Sbjct: 455 FDDKS--MQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAED 512
Query: 1175 QGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHM 1234
S+ S N S S+ G+D G SS + S SS S S
Sbjct: 513 DDSDST------SDTNNSDSNGNGNNGNDD-NDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 1235 SGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKS 1294
S S SS SSS SS S S + S+S +S+SS SS S S S + SS KS
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDS-SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624
Query: 1295 PSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGK 1354
S + + K S ++ S+NSS SS + S
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684
Query: 1355 REKSDKDKSKVSTSGSSVDSSKKT-SESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKP 1413
D S S S S DSS + S+S + + + S S S + +
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 1414 GESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAE 1473
S SS + S S S+ + S+S + + DS S SS +
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 1474 KSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESW 1533
S +S SSD S + + D D D S+ +
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 1534 SKSPISSDQSLSMTSNTILSADRPSRLS 1561
S S SSD S S S+ ++ S S
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSS 892
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 109 bits (273), Expect = 2e-23
Identities = 230/1021 (22%), Positives = 360/1021 (35%), Gaps = 192/1021 (18%)
Query: 540 LPPASSPGYGMTTGNNP--MSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSK 597
L PA S G+ + P +S ++T T T PG P T S+ ++ +
Sbjct: 2955 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP------SLSEKSTTFYTSPRSPD 3008
Query: 598 VSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDF 657
+ +P T+ ++ ST S P H T P S+ P + +
Sbjct: 3009 ATLSPATTTSSGVSEES-STSHSQPGSTHTTAFPDSTTTSGLSQEPTASH------SSQG 3061
Query: 658 STLYGSSPLERQNSSSGSPRMEICSGSNKTKKK-------KSSRLPPEKPKHQTEDDFQR 710
ST SP SS G S T+ S + P H +
Sbjct: 3062 STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 3121
Query: 711 ELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPP----TTYPQPVPHPQPSIQRM 766
L S + + TP+P + P TTY H +PS
Sbjct: 3122 TLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY-----HSRPSSTPT 3176
Query: 767 VRLSSSDSI---GPDVTDILSDIAEEASKL-PSTSDDCPAIGTPLRDSSSSGHSQSTLFD 822
S+S + + T + S + L P+ S +G P SSG +++T
Sbjct: 3177 THFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP 3236
Query: 823 SDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEY 882
+E T SP S T +P S + SG EE
Sbjct: 3237 GSTTTAGLSEKSTT--------FYSSPRSPDTT---------LSPA---STTSSGVSEES 3276
Query: 883 FDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALA 942
S+ G +T P G T G +Q T S L+
Sbjct: 3277 TTSHSRPGST-----------HTTAFP------GSTTMPGVSQESTASHSSPGSTDTTLS 3319
Query: 943 PADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGN-----------------GTSNSTLSG 985
P + S GP TT G T+ + N G+ ++TLS
Sbjct: 3320 PGSTT---ASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 3376
Query: 986 PGLDSKPGKRSRTPS--NDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSP 1043
G ++ G+ + S N + PP A E + SH S P + PT T S S
Sbjct: 3377 AGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGS---PSSTPT-THFSASS 3432
Query: 1044 GSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSS------------GSVSS 1091
+ GRS+ V + P+ T P + G + Y SS + S
Sbjct: 3433 TTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 3492
Query: 1092 SGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGG 1151
G +S SHS ST+ + S+ S S+ + +S +SS GS+ ++ +SS + G
Sbjct: 3493 RGEESTTSHS-------STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG 3545
Query: 1152 KPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNIS--------PSHSRPPGGSD 1203
+ S H + + + + S L+ S + P S P + PG S+
Sbjct: 3546 RSEES-TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 3604
Query: 1204 KL----ASPMKPVPGTPPSSKAKSPISSGSGGSH----MSGTSSSSGMKSSSGLGSSGSL 1255
K +SP P P+S S +S S SH + T++ ++ GL +
Sbjct: 3605 KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 3664
Query: 1256 SQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVV 1315
S +P S+++ T +S ++SGSS S+ + SS G + + S TA+ +
Sbjct: 3665 SHSSPGSTDT-TLLPASTTTSGSSQESTTSH--SSSGSTDTALSPGSTTALSFGQESTTF 3721
Query: 1316 TSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSS 1375
S PG ST+++ P S +TS V++S
Sbjct: 3722 HSSPG-----------STHTTLFPDS------------------------TTSSGIVEAS 3746
Query: 1376 KKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPL 1435
+ STG + +S SP ++ GES+ P AS+ SP
Sbjct: 3747 TRVH-----SSTGSPRTTLSPASSTSPGLQ--------GESTAFQTHP--ASTHTTPSPP 3791
Query: 1436 ISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKS--YQNSPSSDDGIRPLPEYS 1493
+ + P E S ++ +SP TP S + S +EKS + +SP + G P +S
Sbjct: 3792 STATAPVEE--STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA-SGTTPSSAHS 3848
Query: 1494 T 1494
T
Sbjct: 3849 T 3849
Score = 103 bits (256), Expect = 2e-21
Identities = 230/1011 (22%), Positives = 358/1011 (35%), Gaps = 172/1011 (17%)
Query: 540 LPPASSPGYGMTTGNNP--MSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSK 597
L PA S G+ + P +S ++T T T PG P T S+ ++ +
Sbjct: 1398 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP------SLSEKSTTFYTSPRSPD 1451
Query: 598 VSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDF 657
+ +P T+ ++ ST S P H T P S+ + P + +
Sbjct: 1452 ATLSPATTTSSGVSEES-STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSH------SSQG 1504
Query: 658 STLYGSSPLERQNSSSGSPRMEICSGSNKTKKK-------KSSRLPPEKPKHQTEDDFQR 710
ST SP SS G S T+ S + P H +
Sbjct: 1505 STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 1564
Query: 711 ELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPP----TTYPQPVPHPQPSIQRM 766
L S + + TP+P + P TTY H +PS
Sbjct: 1565 TLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY-----HSRPSSTPT 1619
Query: 767 VRLSSSDSI---GPDVTDILSDIAEEASKL-PSTSDDCPAIGTPLRDSSSSGHSQSTLFD 822
S+S + + T + S + L P+ S +G P SSG +++T
Sbjct: 1620 THFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP 1679
Query: 823 SDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEY 882
+E T SP S T +P S + SG EE
Sbjct: 1680 GSTTTAGLSEKSTT--------FYSSPRSPDTT---------LSPA---STTSSGVSEES 1719
Query: 883 FDESSQSGDNDD--FKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKA 940
S+ G F G + M G T + + S S +
Sbjct: 1720 TTSHSRPGSTHTTAFPGSTT---------MPGVSQESTASHSSPGSTDTTLSPGSTTASS 1770
Query: 941 LAPADLMEHHS-GSQGPLL---TTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRS 996
L P H S GS L T G + V G+ ++TLS G ++ G+ S
Sbjct: 1771 LGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGE-S 1829
Query: 997 RTPSNDGKSKDK---PPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPP 1053
T + SKD PP A E + SH S P + PT T S S + GRS+
Sbjct: 1830 TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS---PSSTPT-THFSASSTTLGRSEEST 1885
Query: 1054 GVATPPIPKITIQIPKGTVMVGKPSSHSQYTSS------------GSVSSSGSKSHHSHS 1101
V + P+ T P + G + Y SS + S +S SHS
Sbjct: 1886 TVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHS 1945
Query: 1102 SSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKH 1161
ST+ + S S S+ + +S +SS GS+ ++ +SS + G+ S H
Sbjct: 1946 -------STTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES-TASH 1997
Query: 1162 GLSSGSSSTKMKPQGKPSSLMNPSLSKPNIS--------PSHSRPPGGSDKL----ASPM 1209
+ + + + S L+ S + P S P + PG S+K +SP
Sbjct: 1998 SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR 2057
Query: 1210 KPVPGTPPSSKAKSPISSGSGGSH----MSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNS 1265
P P+S S +S S SH + T++ ++ GL + S +P S+++
Sbjct: 2058 SPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 2117
Query: 1266 CTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPL 1325
T +S ++SG S S+ + SS G + + S TA+ + S PG
Sbjct: 2118 -TLLPASTTTSGPSQESTTSH--SSPGSTDTALSPGSTTALSFGQESTTFHSSPG----- 2169
Query: 1326 DGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVG 1385
ST+++ P S +TS V++S +
Sbjct: 2170 ------STHTTLFPDS------------------------TTSSGIVEASTRVH-----S 2194
Query: 1386 STGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHER 1445
STG + +S SP ++ GES+ P AS+ SP + + P E
Sbjct: 2195 STGSPRTTLSPASSTSPGLQ--------GESTAFQTHP--ASTHTTPSPPSTATAPVEE- 2243
Query: 1446 GSPSHSKSPAYTPQNLDSESESGSSIAEKS--YQNSPSSDDGIRPLPEYST 1494
S ++ +SP TP S + S +EKS + +SP + G P +ST
Sbjct: 2244 -STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA-SGTTPSSAHST 2292
Score = 101 bits (251), Expect = 7e-21
Identities = 217/985 (22%), Positives = 342/985 (34%), Gaps = 129/985 (13%)
Query: 540 LPPASSPGYGMTTGNNP--MSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSK 597
L PA S G+ + P +S ++T T T PG P T S+ ++ +
Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP------SLSEKSTTFYTSPRSPD 4091
Query: 598 VSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDF 657
+ +P T+ ++ ST S P H T P S+ P + +
Sbjct: 4092 ATLSPATTTSSGVSEES-STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSH------SSQG 4144
Query: 658 STLYGSSPLERQNSSSGSPRMEICSGSNKTKKK-------KSSRLPPEKPKHQTEDDFQR 710
ST SP SS G S T+ S + P H +
Sbjct: 4145 STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 4204
Query: 711 ELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPP----TTYPQPVPHPQPSIQRM 766
L S + + TP+P + P TTY H +PS
Sbjct: 4205 TLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTY-----HSRPSSTPT 4259
Query: 767 VRLSSSDSI---GPDVTDILSDIAEEASKL-PSTSDDCPAIGTPLRDSSSSGHSQSTLFD 822
S+S + + T + S + L P+ S +G P SSG +++T
Sbjct: 4260 THFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP 4319
Query: 823 SDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEY 882
+E T SP S T +P S + SG EE
Sbjct: 4320 GSTTTAGLSEKSTT--------FYSSPRSPDTT---------LSPA---STTSSGVSEES 4359
Query: 883 FDESSQSGDNDDFKGFASQALNTLGVP----MLGGDNGETKFKGNNQADTVDFSIISVAG 938
S+ G +++T P M G T + + S S
Sbjct: 4360 TTSHSRPG-----------SMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTA 4408
Query: 939 KALAPADLMEHHS-GSQGPLL---TTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGK 994
+L P H S GS L T G + V G+ ++TLS G ++ G+
Sbjct: 4409 SSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGE 4468
Query: 995 RSRTPS--NDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTP 1052
+ S N + PP A E + SH S P + PT T S S + GRS+
Sbjct: 4469 STTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGS---PSSTPT-THFSASSTTLGRSEES 4524
Query: 1053 PGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSS------------GSVSSSGSKSHHSH 1100
V + P+ T P + G + Y SS + S G +S SH
Sbjct: 4525 TTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSH 4584
Query: 1101 SSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITK 1160
S ST+ + S+ S S+ + +S +SS GS+ ++ +SS + G+ S
Sbjct: 4585 S-------STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES-TAS 4636
Query: 1161 HGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASP-MKPVPGTPPSS 1219
H + + + + S L+ S + P S G + A P PG S
Sbjct: 4637 HSSQDATGTIVLPARSTTSVLLGESTTSPISS-------GSMETTALPGSTTTPGLSEKS 4689
Query: 1220 KAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSG-- 1277
S + +H S +S++ G S S ++ T PS T S S+
Sbjct: 4690 TTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYH 4749
Query: 1278 SSMSSSQNQH--GSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNS 1335
SS S+Q H SS S + S ++ + T+ E+P S +S
Sbjct: 4750 SSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP------TSYHS 4803
Query: 1336 SSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGST------GV 1389
S +++ H G+ E+S S T+G + + T+ + ST G
Sbjct: 4804 SPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGS 4863
Query: 1390 AKIIISKHDGGSPSIKAKVT-LQKPGESSGEGLRP-QMASSKNYGSP--LISGSTPKHER 1445
+ ++ +P + AK T L S + L P M SS G P L S + H
Sbjct: 4864 METTLAS-TATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTT 4922
Query: 1446 GSPSHSKSPAYTPQNLDSESESGSS 1470
P+ + + + ++ S+ GS+
Sbjct: 4923 AFPASTTTSGLSQESTTFHSKPGST 4947
Score = 84.7 bits (208), Expect = 6e-16
Identities = 239/1113 (21%), Positives = 382/1113 (34%), Gaps = 176/1113 (15%)
Query: 518 IQADTPALSLIAETVEDMVKKNLPPASSPGYGM-----TTGNNPMSGTTTP----TNTFP 568
++A TP S + L PASS G+ T + P S TTP T P
Sbjct: 3106 VEASTPTHSSTGS-----LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP 3160
Query: 569 GGPITTLFNMSMSIKDRHES-----VGHGEDFSKVSQNPILT-SLLQITGNGGSTIGSSP 622
TT + S H S +G E+ + V +P T + L T + S + P
Sbjct: 3161 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 3220
Query: 623 TPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICS 682
T P+SS G+T+ + + ++ +T Y SSP R ++ SP S
Sbjct: 3221 TTS-----PISS--GSTETTALPGSTTTAGLSEKSTTFY-SSP--RSPDTTLSPASTTSS 3270
Query: 683 GSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAP 742
G ++ SR + H T P
Sbjct: 3271 GVSEESTTSHSRP--------------------------------------GSTHTTAFP 3292
Query: 743 SQCSTPPTTYPQPVPHPQPSIQRMVRLSSS---DSIGPDVTDILSDIAE-EASKLP--ST 796
+ P + H P S S+GP+ T S E + LP +T
Sbjct: 3293 GSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTT 3352
Query: 797 SDDCPAIGTPLRDSSSSGHS------------QSTLFDSDVFQTNNNENPYTDPA---DL 841
+ TP+ S+ S H+ +ST F S + P T + +L
Sbjct: 3353 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 3412
Query: 842 IADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQ 901
+ GSPSS +PT HF + +S + ++ S G +
Sbjct: 3413 STTSHGSPSS-TPTTHFSASSTTLGR---SEESTTVHSSPVATATTPSPARSTTSGLVEE 3468
Query: 902 ALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTG 961
+ P G T+ ++DT S G+ + H+ S P TT
Sbjct: 3469 STTYHSSP------GSTQTMHFPESDTT-----SGRGEESTTSHSSTTHTISSAPS-TTS 3516
Query: 962 DLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKS 1021
L +E T G S +T P + + G+S++ D G
Sbjct: 3517 ALVEEPTSYHSSPG---STATTHFPD----------SSTTSGRSEESTASHSSQDATGTI 3563
Query: 1022 PSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHS 1081
+ S ST S GS + P TP + + K T P S +
Sbjct: 3564 VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE------KSTTFHSSPRSPA 3617
Query: 1082 QYTSSGSVSSSG----SKSHHS-----HSSSSSSSASTSGKMKSS----KSEGSSSSKLS 1128
S S +SSG S + HS H+++ S +T G + S S GS+ + L
Sbjct: 3618 TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 3677
Query: 1129 SSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKM--KPQGKPSSLMNPSL 1186
+ ++ GSS S + +SS SP + LS G ST P ++L S
Sbjct: 3678 PASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 3737
Query: 1187 SKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKS------PISSGSGGSHMSGTSSS 1240
+ I + +R + + + P T P + +S P S+ + S S T+++
Sbjct: 3738 TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS-TATA 3796
Query: 1241 SGMKSSSGLGSSGS-------LSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGK 1293
+S++ S GS S T S T SS +SG++ SS+ + S +G+
Sbjct: 3797 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST-TSGRGE 3855
Query: 1294 SPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQ- 1352
S + P T +T+ P G G ST S P S +S
Sbjct: 3856 STTSRISPGSTE---------ITTLP-GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTS 3905
Query: 1353 -GKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSI---KAKV 1408
G E+S +S+ ++ S+V + T+ + ST + S G + + ++
Sbjct: 3906 LGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEEST----TVYSSSPGSTETTVFPRSTT 3961
Query: 1409 TLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESG 1468
T + E + RP + + + + P SPA T L + +
Sbjct: 3962 TSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG---SPASTQTGLPATLTTA 4018
Query: 1469 SSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSI 1528
E + S S G + P ST + ++ + S S
Sbjct: 4019 DLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE 4078
Query: 1529 KPESWSKSPISSDQSLSMTSNTILSADRPSRLS 1561
K ++ SP S D +LS + T S S
Sbjct: 4079 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 4111
Score = 83.6 bits (205), Expect = 1e-15
Identities = 254/1195 (21%), Positives = 414/1195 (34%), Gaps = 213/1195 (17%)
Query: 531 TVEDMVKKNLPPASSPGYGMTT---GNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHE 587
T+ + +++ SSPG TT G+ S + TF GP +T + + D
Sbjct: 3296 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTL---LPDNTT 3352
Query: 588 SVGHGEDFSKV-----SQNPILTSLLQITGNGGSTIGSS-PTPPHHTPPPVSSMAGNTKN 641
+ G E + V S + L+ T G ST S P TP P ++ + +
Sbjct: 3353 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 3412
Query: 642 HPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICSGSNKTKKKKS-SRLPPEKP 700
P FS S+ L R S+ + + + + + + S L E
Sbjct: 3413 STTSHGSPSSTPTTHFSA--SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 3470
Query: 701 KHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCST---PPTTYPQPVP 757
+ + + + + D+ + + + T+ + T I+ APS S PT+Y
Sbjct: 3471 TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY----- 3525
Query: 758 HPQPSIQRMVRL-SSSDSIGPDVTDILSDIAEEASK---LPSTSDDCPAIGTPLRDSSSS 813
H P SS + G S +++A+ LP+ S +G SS
Sbjct: 3526 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 3585
Query: 814 GHSQSTLFDSDVFQTNNNENPYT------DPADLIADAAGSPS--SDSPTNHFFHDGVDF 865
G ++T +E T PA ++ A+ + S S+ T G
Sbjct: 3586 GSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTH 3645
Query: 866 NPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQ 925
+S + G S G D T +P T G++Q
Sbjct: 3646 TTAFPDSTTTPGLSRHSTTSHSSPGSTD-----------TTLLP------ASTTTSGSSQ 3688
Query: 926 ADTVDFSIISVAGKALAPADLMEHHSGSQGPLL--------------TTGDLGKEKTQKR 971
T S AL+P G + +T G + R
Sbjct: 3689 ESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTR 3748
Query: 972 VKEGNGTSNSTLSGPGLDSKPGKRS-----RTPSNDGKSKDKPPKRKKADTE-------- 1018
V G+ +TLS P + PG + +T + PP A E
Sbjct: 3749 VHSSTGSPRTTLS-PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 3807
Query: 1019 -GKSPS-------------------HSSSNRPFTPPTS-----------TGGSKSPGSAG 1047
G +P+ HSS + T P+S T SPGS
Sbjct: 3808 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 3867
Query: 1048 RSQTPPGVATPPIPKITIQI---PKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSS 1104
+ P TP + + + P+ P+S + ++S S+ +HS+ S
Sbjct: 3868 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 3927
Query: 1105 SSSASTSGKMKSSKSEGSSSSKLS-------------------------SSMYSSQGSSG 1139
+S +T G + S + SSS + +S +++ +
Sbjct: 3928 PASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTED 3987
Query: 1140 SSQSKNSSQSGGKPGSSPITKHGL------------------SSGSSSTKMKP------- 1174
S+ S + +S PGS T+ GL SSGS+ TK+ P
Sbjct: 3988 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 4047
Query: 1175 ---QGKPSSLMNPSLSKPNISPSHSRPPGGSDK----LASPMKPVPGTPPSSKAKSPISS 1227
+ PS L +PS ++ P P S+K SP P P++ S +S
Sbjct: 4048 LVGESTPSRL-SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE 4106
Query: 1228 GSGGSH-MSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQ 1286
S SH G++ ++ S+ ++ LSQ+ P +S+S S+ + S GS+ +SS Q
Sbjct: 4107 ESSTSHSQPGSTHTTAFPDST---TTSGLSQE-PTTSHSSQGSTEATLSPGSTTASSLGQ 4162
Query: 1287 HGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNM 1346
++ SP + L D + G+V + P G S +++ P SS
Sbjct: 4163 QSTTFHSSPGDTETTLLPD--DTITSGLVEA----STPTHSSTG-SLHTTLTPASSTSTG 4215
Query: 1347 SGGE---FQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPS 1403
E FQ SD S ST+ V+ S T+ ST S G S
Sbjct: 4216 LQEESTTFQSWPSSSDTTPSPPSTTAVPVEVS--TTYHSRPSSTPTTHFSASSTTLGR-S 4272
Query: 1404 IKAKVTLQKPGESSGEGLRP-QMASSKNYG----SPLISGSTPKH-----------ERGS 1447
++ PG ++G L P + A+S G SP+ SGST S
Sbjct: 4273 EESTTVHSSPG-ATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKS 4331
Query: 1448 PSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKV 1507
+ SP L S + S ++E+S S S + S+ +E
Sbjct: 4332 TTFYSSPRSPDTTLSPASTTSSGVSEES-TTSHSRPGSMHTTAFPSSTTMPGVSQESTAS 4390
Query: 1508 KDKDRDRDRDKDRDKKKSHSIKPES--WSKSPISSDQSL---SMTSNTILSADRP 1557
D + S+ PES + SP S++ +L + T++ +L A P
Sbjct: 4391 HSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTP 4445
Score = 82.4 bits (202), Expect = 3e-15
Identities = 217/1103 (19%), Positives = 367/1103 (33%), Gaps = 143/1103 (12%)
Query: 542 PASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQN 601
P S+ G++ + + PT+T TT ++ H G E + + N
Sbjct: 680 PGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTET-TLLPDN 738
Query: 602 PILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMA--GNTKNHPMLMNLLKDNPAQDFST 659
+ LL+ + + SS PH T P S G + + PA +T
Sbjct: 739 TTASGLLEAS----MPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTT 794
Query: 660 LYGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDS 719
S+ +E +S GSP ++ + + +S L E + + + + + D+
Sbjct: 795 ---SAFVEPSTTSHGSPSS--IPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT 849
Query: 720 QNPIFDVNMTADTLDTPHITPAPSQCST---PPTTYPQPVPHPQPSIQRMVRL-SSSDSI 775
+ + + T+ + T I+ APS S PT+Y H P SS +
Sbjct: 850 TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY-----HSSPGSTATTHFPDSSTTS 904
Query: 776 GPDVTDILSDIAEEASK---LPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNE 832
G S +++A+ LP+ S +G SSG ++T +E
Sbjct: 905 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 964
Query: 833 NPYT------DPADLIADAAGSPS--SDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFD 884
T PA ++ A+ + S S+ T G +S + G
Sbjct: 965 RSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTT 1024
Query: 885 ESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPA 944
S G D T +P T G +Q T S AL+P
Sbjct: 1025 SHSSPGSTD-----------TTLLP------ASTTTSGPSQESTTSHSSSGSTDTALSPG 1067
Query: 945 DLMEHHSGSQGPLL--------------TTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDS 990
G + +T G + RV G+ +TLS P +
Sbjct: 1068 STTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS-PASST 1126
Query: 991 KPGKRS-----RTPSNDGKSKDKPPKRKKADTE---------GKSPS------------- 1023
PG + +T + PP A E G +P+
Sbjct: 1127 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 1186
Query: 1024 ------HSSSNRPFTPPTS-----------TGGSKSPGSAGRSQTPPGVATPPIPKITIQ 1066
HSS + T P+S T SPGS + P TP + + +
Sbjct: 1187 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAS-- 1244
Query: 1067 IPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSK 1126
T P S + S S++S G + S S S ++ S+ + G S
Sbjct: 1245 ----TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE- 1299
Query: 1127 LSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSL 1186
S+++YSS S + S + G P T H + + +T S L S
Sbjct: 1300 -STTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 1358
Query: 1187 SKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSS 1246
+ P SP AS +P T ++ ++ S +GT S ++
Sbjct: 1359 AFPG-SP------------ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTT 1405
Query: 1247 SGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAV 1306
SGL + S+ +P S+ + T S + S S S++ + +SP P+ T
Sbjct: 1406 SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTT----FYTSPRSPDATLSPATTTS 1461
Query: 1307 IDKLKHGVVT-SGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKV 1365
+ + S PG +T+ S ++ H+ S G + S +
Sbjct: 1462 SGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS-SQGSTEATLSPGSTTASSL 1520
Query: 1366 STSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQM 1425
++ SS +E+ + + ++ S + T P S+ GL+ +
Sbjct: 1521 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEES 1580
Query: 1426 ASSKNYGS-----PLISGSTPKHERGSPSHSKSPAYTPQNLDSESES--GSSIAEKSYQN 1478
+ +++ S P G+T S ++ P+ TP S S + G S + +
Sbjct: 1581 TTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHS 1640
Query: 1479 SPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPI 1538
SP + G P S + + + S K ++ SP
Sbjct: 1641 SPGA-TGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 1699
Query: 1539 SSDQSLSMTSNTILSADRPSRLS 1561
S D +LS S T S S
Sbjct: 1700 SPDTTLSPASTTSSGVSEESTTS 1722
Score = 80.5 bits (197), Expect = 1e-14
Identities = 241/1053 (22%), Positives = 365/1053 (34%), Gaps = 156/1053 (14%)
Query: 540 LPPASSPGYGMT---TGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFS 596
L PAS+ G++ T ++ G+T T FPG TT+ +S H S G +
Sbjct: 1705 LSPASTTSSGVSEESTTSHSRPGSTH-TTAFPGS--TTMPGVSQESTASHSSPGSTDT-- 1759
Query: 597 KVSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQD 656
T + GST SS P T S G+T+ LL DN
Sbjct: 1760 --------------TLSPGSTTASSLGPESTT---FHSSPGSTET-----TLLPDNTTAS 1797
Query: 657 FSTLYGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMD 716
L S+P+ +SS+GSP + + T++ +S+ FQ S D
Sbjct: 1798 -GLLEASTPV---HSSTGSPHTTLSPAGSTTRQGESTT-------------FQSWPSSKD 1840
Query: 717 VDSQNPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIG 776
P + + T H +P+ STP T H S + R S ++
Sbjct: 1841 TMPAPPT-TTSAFVELSTTSHGSPS----STPTT-------HFSASSTTLGRSEESTTVH 1888
Query: 777 PDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYT 836
S +A + P+ S + SS G +Q+ F + +E T
Sbjct: 1889 S------SPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1942
Query: 837 DPADLIADAAGSPSSDS-----PTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGD 891
+ + PS+ S PT++ G +S + SG EE S+ S
Sbjct: 1943 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE----STASHS 1998
Query: 892 NDDFKG-FASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEH- 949
+ D G A +T V L G++ + + T ++ G P L E
Sbjct: 1999 SQDATGTIVLPARSTTSV--LLGESTTSPISSGSMETT------ALPGSTTTPG-LSEKS 2049
Query: 950 ---HSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSK 1006
HS + P T T V E + TS+S +PG T D S
Sbjct: 2050 TTFHSSPRSPATTLSPAST--TSSGVSEESTTSHS---------RPGSTHTTAFPD--ST 2096
Query: 1007 DKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQ 1066
P + + T SP S++ P ++T S S +P T P T
Sbjct: 2097 TTPGLSRHSTTSHSSPG--STDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTA 2154
Query: 1067 IPKG---TVMVGKPSSHSQYTSSGSVSSSG--SKSHHSHSSSSS-----SSASTSGKMKS 1116
+ G T P S S +SSG S HSS+ S S AS++
Sbjct: 2155 LSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQ 2214
Query: 1117 SKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQG 1176
+S + S+ S S+ ++ + S+ PGS+P T SS +S K
Sbjct: 2215 GESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 2274
Query: 1177 KPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSG 1236
SS P S S +HS G + S + P + I++ G + G
Sbjct: 2275 FHSS---PDASGTTPSSAHSTTSGRGESTTSRISP---------GSTEITTLPGSTTTPG 2322
Query: 1237 TSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMS----SSQNQHGSSKG 1292
S +S SS + +LS + S S++S S GS+ S +S G S+
Sbjct: 2323 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 2382
Query: 1293 KSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQ 1352
+ + P T + T+ GE+P T S P +S H E
Sbjct: 2383 STTVYSSSPGSTET--TVFPRTPTTSVRGEEP--------TTFHSRP-ASTHTTLFTEDS 2431
Query: 1353 GKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQK 1412
+++ + + S+ T + ++G S G + S T
Sbjct: 2432 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2491
Query: 1413 PGESSGEGLRPQMASSKNY-GSPLISGSTPKH-----ERGSPSHSKSPAYTPQNLDSESE 1466
GES+ L P + GSP + K SP + SPA T + SE
Sbjct: 2492 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 2551
Query: 1467 SGSSIAEKSYQNSPSSDDGIRP-LPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKS 1525
S S S + D P L +ST H + ++ S
Sbjct: 2552 STSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS-GPSQESTTS 2610
Query: 1526 HSIKPESWSKSPISSDQSLSMTSNTILSADRPS 1558
HS SP S+D +LS S T LS + S
Sbjct: 2611 HS--------SPGSTDTALSPGSTTALSFGQES 2635
Score = 77.4 bits (189), Expect = 1e-13
Identities = 245/1117 (21%), Positives = 399/1117 (35%), Gaps = 223/1117 (19%)
Query: 541 PPASSPGYGMTTGNNPMSGTTTPTNTFPGGPIT-------TLFNMSMSIKDRHESVGH-- 591
PP+++ + S +TPT FP T T+F+ S S H
Sbjct: 3790 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 3849
Query: 592 --GEDFSKVSQ-NPILTSLLQITGN--------GGSTIGSSPTPPHHTPPPVS------- 633
G S S+ +P T + + G+ +T SSP P T P S
Sbjct: 3850 TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 3909
Query: 634 -------SMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICSGSNK 686
S G+T + + +++ +T+Y SSP GS + S
Sbjct: 3910 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSP--------GSTETTVFPRSTT 3961
Query: 687 TKKKKSSRLPPEKPK--HQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQ 744
T ++ E+P H LF+ D + +T ++ P +PA +Q
Sbjct: 3962 TSVRR------EEPTTFHSRPASTHTTLFTEDSTTSG------LTEESTAFPG-SPASTQ 4008
Query: 745 CSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKL-PSTSDDCPAI 803
P T L+++D +G + T S +KL P+ S +
Sbjct: 4009 TGLPAT------------------LTTAD-LGEESTTFPSSSGSTGTKLSPARSTTSGLV 4049
Query: 804 G--TPLRDSSSSGHSQSTLFDSDVFQTNNNENP--YTDPADLIADAAGSP--------SS 851
G TP R S SS + +TL S + + ++ YT P DA SP S
Sbjct: 4050 GESTPSRLSPSSTET-TTLPGSPTTPSLSEKSTTFYTSPRS--PDATLSPATTTSSGVSE 4106
Query: 852 DSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPML 911
+S T+H G +S + SG +E S G + S ++LG
Sbjct: 4107 ESSTSHS-QPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLG---- 4161
Query: 912 GGDNGETKFKGNNQADTV---DFSIISVAGKALAPADLMEHHSGSQGPLLTT------GD 962
T +T D +I S +A P HS S G L TT
Sbjct: 4162 --QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT-----HS-STGSLHTTLTPASSTS 4213
Query: 963 LGKEKTQKRVKEGNGTSNSTLSGPGLDSKP--------GKRSRTPSND--------GKSK 1006
G ++ + +S++T S P + P + S TP+ G+S+
Sbjct: 4214 TGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE 4273
Query: 1007 DKPPKRKKADTEGKS--PSHSSSN----RPFTPPTSTGGSKS---PGS---AGRSQTPPG 1054
+ G + P+ S+++ P T P S+G +++ PGS AG S+
Sbjct: 4274 ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 4333
Query: 1055 VATPPIPKITIQIPKGTVMVG----KPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAST 1110
+ P T P T G +SHS+ S + + S + S S++S S+
Sbjct: 4334 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSS 4393
Query: 1111 SGKMKSSKSEGSSSSKL----SSSMYSSQGSSGSSQ-SKNSSQSGGKPGSSPITKHGLSS 1165
G ++ S GS+++ S++ +SS GS+ ++ N++ SG S+P+ S+
Sbjct: 4394 PGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHS---ST 4450
Query: 1166 GSSSTKMKPQGKPSSLMNPSL--SKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKA-- 1221
GS T + P G + + S PN + PP + G+P S+
Sbjct: 4451 GSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTH 4510
Query: 1222 ------------------KSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSS 1263
SP+++ + S T+S +S++ S GS P S
Sbjct: 4511 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 4570
Query: 1264 NSCTA----SSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGP 1319
N+ + S++S SS+ ++SS+ + + + S + P TA TSG
Sbjct: 4571 NTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH-FPDSSTTSGR 4629
Query: 1320 GGEDPLDGQ-------------------MGVSTNS--SSHPMSSKHNMSGGEFQGKREKS 1358
E +G ST S SS M + G EKS
Sbjct: 4630 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 4689
Query: 1359 DKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTL-------- 1410
S S++ ++ S+ T+ ++ ST V ++ SP+ L
Sbjct: 4690 TTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYH 4749
Query: 1411 QKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSP------------SHSKSPAYTP 1458
PG + +S S S+ H SP S+ SP
Sbjct: 4750 SSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIA 4809
Query: 1459 QNLDSESESGSSIAEKSYQNSPSSD-DGIRPLPEYST 1494
ES + S +E+S + S D +GI PLP + T
Sbjct: 4810 TTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFT 4846
Score = 76.3 bits (186), Expect = 2e-13
Identities = 219/1093 (20%), Positives = 362/1093 (33%), Gaps = 118/1093 (10%)
Query: 541 PPASSPGYGMTTGNNPMSGTTTPTNTFPGGPIT-------TLFNMSMSIKDRHESVGH-- 591
PP+++ + S +TPT FP T T+F+ S S H
Sbjct: 2233 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 2292
Query: 592 --GEDFSKVSQ-NPILTSLLQITGN--------GGSTIGSSPTPPHHTPPPVSSMAGNTK 640
G S S+ +P T + + G+ +T SSP P T P S +
Sbjct: 2293 TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 2352
Query: 641 NHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKP 700
+ P ST+ +S S + GS +T + P P
Sbjct: 2353 EESTTS---RSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETT------VFPRTP 2403
Query: 701 KHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHI----TPAPSQCSTPPT------ 750
+ S + +F + T L +PA +Q P T
Sbjct: 2404 TTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADL 2463
Query: 751 -----TYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLP------STSDD 799
T+P ++ R ++S +G LS + E + LP S S+
Sbjct: 2464 GEESTTFPSSSGSTGTTLSP-ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK 2522
Query: 800 CPAIGTPLRDSSSSGHSQSTLFDSDVFQ--TNNNENPYTDPADLIADAAGSP--SSDSPT 855
T R S + S +T S V + + ++ P + D+ +P S S T
Sbjct: 2523 STTFYTSPR-SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTT 2581
Query: 856 NHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDN 915
+H D L S + SG +E S G D AL+ L
Sbjct: 2582 SHSSPGSTDTTL-LPASTTTSGPSQESTTSHSSPGSTDT-------ALSPGSTTALSFGQ 2633
Query: 916 GETKFKGNNQADTVDFSIISVAGKALAPADLMEHHS-GSQGPLLTTGDL---GKEKTQKR 971
T F + + S + A H S GS L+ G +
Sbjct: 2634 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTT 2693
Query: 972 VKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPS----HSSS 1027
+ ++++T S P + P + S T S + T G S HSS
Sbjct: 2694 FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP 2753
Query: 1028 NRPFTPPTS-----------TGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGK 1076
+ T P+S T SPGS + P TP + + + T
Sbjct: 2754 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAS------TTFYSS 2807
Query: 1077 PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQG 1136
P S + S S++S G + S S S ++ S+ + G S S+++YSS
Sbjct: 2808 PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE--STTVYSSSP 2865
Query: 1137 SSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHS 1196
S + S + G P T H + + +T S L S + P SP
Sbjct: 2866 GSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG-SP--- 2921
Query: 1197 RPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS 1256
AS +P T ++ ++ S +GT+ S ++SGL + S
Sbjct: 2922 ---------ASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPS 2972
Query: 1257 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVT 1316
+ +P S+ + T S + S S S++ + +SP P+ T + +
Sbjct: 2973 RLSPSSTETTTLPGSPTTPSLSEKSTT----FYTSPRSPDATLSPATTTSSGVSEESSTS 3028
Query: 1317 -SGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSS 1375
S PG +T+ S ++ H+ S G + S + ++ SS
Sbjct: 3029 HSQPGSTHTTAFPDSTTTSGLSQEPTASHS-SQGSTEATLSPGSTTASSLGQQSTTFHSS 3087
Query: 1376 KKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGS-- 1433
+E+ + + ++ S + T P S+ GL+ + + +++ S
Sbjct: 3088 PGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS 3147
Query: 1434 ---PLISGSTPKHERGSPSHSKSPAYTPQNLDSESES--GSSIAEKSYQNSPSSDDGIRP 1488
P G+T S ++ P+ TP S S + G S + +SP + G
Sbjct: 3148 DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGA-TGTAL 3206
Query: 1489 LPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTS 1548
P S + + + S K ++ SP S D +LS S
Sbjct: 3207 FPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 3266
Query: 1549 NTILSADRPSRLS 1561
T S S
Sbjct: 3267 TTSSGVSEESTTS 3279
Score = 73.2 bits (178), Expect = 2e-12
Identities = 224/1026 (21%), Positives = 355/1026 (34%), Gaps = 164/1026 (15%)
Query: 518 IQADTPALSLIAETVEDMVKKNLPPASSPGYGM-----TTGNNPMSGTTTP----TNTFP 568
++A TP S + L PASS G+ T + P S TTP T P
Sbjct: 4189 VEASTPTHSSTGS-----LHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVP 4243
Query: 569 GGPITTLFNMSMSIKDRHES-----VGHGEDFSKVSQNPILT-SLLQITGNGGSTIGSSP 622
TT + S H S +G E+ + V +P T + L T + S + P
Sbjct: 4244 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 4303
Query: 623 TPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICS 682
T P+SS G+T+ + + ++ +T Y SSP R ++ SP S
Sbjct: 4304 TTS-----PISS--GSTETTALPGSTTTAGLSEKSTTFY-SSP--RSPDTTLSPASTTSS 4353
Query: 683 GSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAP 742
G ++ SR + H T P
Sbjct: 4354 GVSEESTTSHSRP--------------------------------------GSMHTTAFP 4375
Query: 743 SQCSTPPTTYPQPVPHPQPSIQRMVRLSSS---DSIGPDVTDILSDIAE-EASKLP--ST 796
S + P + H P S S+GP+ T S E + LP +T
Sbjct: 4376 SSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTT 4435
Query: 797 SDDCPAIGTPLRDSSSSGHS------------QSTLFDSDVFQTNNNENPYTDPA---DL 841
+ TP+ S+ S H+ +ST F S + P T + +L
Sbjct: 4436 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 4495
Query: 842 IADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQ 901
+ GSPSS +PT HF + +S + ++ S G +
Sbjct: 4496 STTSHGSPSS-TPTTHFSASSTTLGR---SEESTTVHSSPVATATTPSPARSTTSGLVEE 4551
Query: 902 ALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTG 961
+ P G T+ +++T S G+ + H+ S P TT
Sbjct: 4552 STTYHSSP------GSTQTMHFPESNTT-----SGRGEESTTSHSSTTHTISSAPS-TTS 4599
Query: 962 DLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKS 1021
L +E T G S +T P + + G+S++ D G
Sbjct: 4600 ALVEEPTSYHSSPG---STATTHFPD----------SSTTSGRSEESTASHSSQDATGTI 4646
Query: 1022 PSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHS 1081
+ S ST S GS + P TP + + K T PSS
Sbjct: 4647 VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE------KSTTFHSSPSSTP 4700
Query: 1082 QYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSS 1141
T+ S SS+ ++ SS +T+ ++S S + S++ +SS GS+ +
Sbjct: 4701 --TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTM 4758
Query: 1142 QSKNSSQSGGKPGSSPI----TKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSR 1197
SS + G+ S T H +SS S+T + S +P P S
Sbjct: 4759 HFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESST 4818
Query: 1198 PPGGSDKL----ASP----MKPVPG--TPPSSKAKSP---ISSGSGGSHMSGTSSSSGMK 1244
G S++ +SP + P+P T A+S IS GS + ++ T+++ G+
Sbjct: 4819 TSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLS 4878
Query: 1245 SSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLT 1304
+ S + S S S P AS +S S SG S + P+ L+
Sbjct: 4879 AKSTILYSSSRS----PDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLS 4934
Query: 1305 AVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDK--DK 1362
+ S PG + ++T+S + ++ H+ G S
Sbjct: 4935 Q-----ESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGL 4989
Query: 1363 SKVSTSGSSVDSSKKT---SESKNVGSTGVAKIIISKHDGGSPSI-KAKVTLQKPGESSG 1418
S+ ST+ S S +T S S + G + ++ A +T G+
Sbjct: 4990 SEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQ--- 5046
Query: 1419 EGLRPQMASSKNYGSPLISGSTPKHERGSPSH---SKSPAYTPQNLDSESESGSSIAEKS 1475
E +S +PL + ST G P+ S SP YT S S SG + +
Sbjct: 5047 ESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTT 5106
Query: 1476 YQNSPS 1481
+ SPS
Sbjct: 5107 FHTSPS 5112
Score = 58.2 bits (139), Expect = 6e-08
Identities = 127/605 (20%), Positives = 222/605 (36%), Gaps = 98/605 (16%)
Query: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
+SP + + T++G S+ + S T +TP + + ++
Sbjct: 506 RSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETT 565
Query: 1080 HSQYTSSGSVSSSGSKSHHSHSSS------------------SSSSASTSGKMKSSKSEG 1121
H + +S+ S S SK+ HS + S+ S +SG M+++ G
Sbjct: 566 HFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPG 625
Query: 1122 SSS----SKLSSSMYSSQGS----------SGSSQSKNSSQSGGKPGSS-------PITK 1160
S++ S+ S++ YSS S + S S+ S+ S +PGS+ T
Sbjct: 626 STTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 685
Query: 1161 HGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPS----HSRPPGGSDKLASPMKPVPGTP 1216
GLS S+++ P ++L S + ++ P HSRP L G
Sbjct: 686 PGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGL- 744
Query: 1217 PSSKAKSPISSGSGGSHM----SGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSC-----T 1267
+A P+ S + H +G+++ G ++ S ++ PP++ S T
Sbjct: 745 --LEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST 802
Query: 1268 ASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDG 1327
S S SS ++ S+++ +S + + P T + TSG G E
Sbjct: 803 TSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM-HFPESDTTSGRGEEST--- 858
Query: 1328 QMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKV--------STSGSSVDSSKKTS 1379
S +S++H +SS + + + S +TSG S +S+ S
Sbjct: 859 ---TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 915
Query: 1380 ESKNVG-----STGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSP 1434
G + +++ + S + T PG ++ GL + S+ + SP
Sbjct: 916 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSER--STTFHSSP 973
Query: 1435 LISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRP-LPEYS 1493
SP+ + SPA T + SE + S S + D P L +S
Sbjct: 974 -----------RSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHS 1022
Query: 1494 TEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILS 1553
T H + ++ SHS S S+D +LS S T LS
Sbjct: 1023 TTSHSSPGSTDTTLLPASTTTS-GPSQESTTSHS--------SSGSTDTALSPGSTTALS 1073
Query: 1554 ADRPS 1558
+ S
Sbjct: 1074 FGQES 1078
Score = 50.1 bits (118), Expect = 2e-05
Identities = 161/739 (21%), Positives = 266/739 (35%), Gaps = 89/739 (12%)
Query: 805 TPLRDSSSSGHSQ---STLFDSDVFQTNNNENPYT-DPADLIADAAGSPS---SDSPTNH 857
T + S+ SG SQ ST+ S T + P + DP +D S + + T H
Sbjct: 151 TVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKH 210
Query: 858 FFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKG------FASQALNTLGVPML 911
F + ++ S SG G F G S ++ T +P
Sbjct: 211 FLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALP-- 268
Query: 912 GGDNGETKFKGNNQADTVDFSIISVAGKALAPA-----DLMEHHSGSQ---GPLLTTGDL 963
G T G ++ T +S + L+PA + E + S GP T
Sbjct: 269 ----GSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIA-F 323
Query: 964 GKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPS 1023
T V + + S+S PG + TPS+ G ++ T SP
Sbjct: 324 PDSTTMPGVSQESTASHSIPGSTDTTLSPG--TTTPSSLGP---------ESTTFHSSPG 372
Query: 1024 HSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQY 1083
++ + R T++G ++ S P P T + T S +
Sbjct: 373 YTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSP 432
Query: 1084 TSSGSVSSSGSKSHHSHSSSSSS-----SASTSGKMKSSKSEGSSSSKLSSSMYSSQGSS 1138
SG+ S+ S HSS SS+ SAS++ S +S SS ++++ S
Sbjct: 433 APSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARS 492
Query: 1139 GSS----------QSKNSSQSGGKPGSSPITKHGLSS-----GSSSTKMKPQGKPSSLMN 1183
+S +S S+Q+ P SS + H S ++ TK ++L +
Sbjct: 493 ATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAH 552
Query: 1184 PSL--SKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSS 1241
S S + +H R + K + P + A + + +GS S + G S+ S
Sbjct: 553 TSYHSSLGSTETTHFRDSSTISGRSEESK-ASHSSPDAMATTVLPAGSTPSVLVGDSTPS 611
Query: 1242 GMKSSSGLGSSGSLSQKTPP--SSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNK 1299
+ SS + ++ T P S S T SS S + + +S G S+ +S + +
Sbjct: 612 PI-SSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSE-ESTTSHS 669
Query: 1300 KPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSD 1359
+P T T+ G + G ST S S P + +S G +
Sbjct: 670 RPGSTH----------TTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGS-----TTAS 714
Query: 1360 KDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGE 1419
+ +T S S++ T N ++G+ + + H S + TL G ++ +
Sbjct: 715 SLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVH---SSTRSPHTTLSPAGSTTRQ 771
Query: 1420 GLRPQMAS--SKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKS-- 1475
G S S P +T S + SP+ P S + S + E+S
Sbjct: 772 GESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTT 831
Query: 1476 YQNSPSSDDGIRPLPEYST 1494
Y +SP S + PE T
Sbjct: 832 YHSSPGSTQTMH-FPESDT 849
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 104 bits (259), Expect = 8e-22
Identities = 190/707 (26%), Positives = 257/707 (36%), Gaps = 122/707 (17%)
Query: 847 GSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTL 906
GS S SP + G +P S SG G++ F S + +
Sbjct: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSS 2118
Query: 907 GVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKE 966
G +G + G + G + E H S G G G
Sbjct: 2119 SYSQHGSGSGHSSGYGQH-------------GSRSGQSSRGERHGSSSGSSSRYGQHGSG 2165
Query: 967 KTQK--RVKEGNGTSNSTL-----SGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
Q ++G+G+ +S SG G S G+ S G+S + P ++
Sbjct: 2166 SRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHG---SGSGRSSSRGPYESRSGHSS 2222
Query: 1020 KSPSHSSSNRPFTPPTSTG-GSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPS 1078
H S + + + G GS S G+ + G ++ + G+ S
Sbjct: 2223 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST--------FDQEGSSTGQSS 2274
Query: 1079 SHSQYTSSGSVSSS----GSKSHHS-----------HSSSSSSSASTSGKMKSSKSEGSS 1123
SH Q+ S S SSS GS S S HSSS S SG SS GS
Sbjct: 2275 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 2334
Query: 1124 SSKLS------SSMYSSQG----SSGSSQSKNSSQSGGKPG-SSPITKHGLSSGSSSTK- 1171
S + S SS + S G SGS S + Q G + G SS +HG SSGSSS+
Sbjct: 2335 SGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG 2394
Query: 1172 MKPQGKPSSL---MNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSG 1228
G SL + S S + SPS R GS + +S P S ++ P SG
Sbjct: 2395 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ-SSSYSPYGSGSGWSSSRGPYESG 2453
Query: 1229 SGGSH-------MSGTSSSSGMK-SSSGLGSSGSLSQKTPPSSNSCT---ASSSSFSS-- 1275
SG S SG SS G SSSG S+ T S+SC ASS SS
Sbjct: 2454 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 2513
Query: 1276 ---SGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVS 1332
SGSS SS + GS G+SP HG SG + P G+ G
Sbjct: 2514 QHGSGSSQSSGYGRQGSGSGQSPG---------------HGQRGSG-SRQSPSYGRHGSG 2557
Query: 1333 TNSSSHPMSSKHNMSGGEFQ--GKREKSDKDKSKVSTSGSSVDSSK----------KTSE 1380
+ SS S +H GE G E S S S GS S ++S
Sbjct: 2558 SGRSS--SSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2615
Query: 1381 SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPL-ISGS 1439
+ GS+ + +H GS + + + SG G P S +GS L S S
Sbjct: 2616 GERHGSSSGSSSHYGQHGSGS-----RQSSGHGRQGSGSGQSP---SRGRHGSGLGHSSS 2667
Query: 1440 TPKHERGSPSHSKSPAYTPQ----NLDSESESGSSIAEKSYQNSPSS 1482
+H GS S Y + ++ + ESGS + Q+ S
Sbjct: 2668 HGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS 2714
Score = 101 bits (252), Expect = 5e-21
Identities = 138/449 (30%), Positives = 175/449 (38%), Gaps = 50/449 (11%)
Query: 1078 SSHSQYTSSGSVSSSGSKSHHSHSS-SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQG 1136
SS SGS S H S S SSS+ SG +SS SS SS YS G
Sbjct: 189 SSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHG 248
Query: 1137 SSGSSQSKNSSQSGGKPG-SSPITKHGLSSGSSSTKMKPQGKPSSLMNPSL------SKP 1189
SGS S Q G + G SS +H SSGSSS+ G+ S SL S
Sbjct: 249 -SGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS----YGQHGSGSRQSLGHGRQGSGS 303
Query: 1190 NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSG-----GSHMSGTSSSSG-M 1243
SPSH R GS +S + G+ S ++ SGSG G H SG+ SSG
Sbjct: 304 RQSPSHVRHGSGSGHSSSHGQHGSGS-SYSYSRGHYESGSGQTSGFGQHESGSGQSSGYS 362
Query: 1244 KSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSL 1303
K SG G S S Q S S ASSS S S SSS QH S+ S R + S
Sbjct: 363 KHGSGSGHSSSQGQH---GSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSG 419
Query: 1304 TAVIDKLKHGVVTSGPGGEDPLDGQ--MGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKD 1361
+ HG SG G+ P GQ G +SSS P S S G G E S +
Sbjct: 420 SG--QSPGHGQRGSG-SGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSG--FGHHESSSEH 474
Query: 1362 KSKVSTSGSSVDSSK----------KTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQ 1411
S + GS S ++S + GS+ + +H GS + +L
Sbjct: 475 SSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGS-----RQSLG 529
Query: 1412 KPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSI 1471
SG G P + ++ S S H GS S Y +S S S +
Sbjct: 530 HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPY-----ESGSGHSSGL 584
Query: 1472 AEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500
+ ++ SS G + H +H
Sbjct: 585 GHQESRSGQSSGYGQHGSSSGHSSTHGQH 613
Score = 99.8 bits (247), Expect = 2e-20
Identities = 168/677 (24%), Positives = 231/677 (34%), Gaps = 77/677 (11%)
Query: 846 AGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNT 905
+G SS P + G + L + +S+SG Y S SG + S + +
Sbjct: 565 SGRSSSRGP----YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 620
Query: 906 LGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGK 965
G +G++ G + + + S G + H G + G G
Sbjct: 621 SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGS 680
Query: 966 EKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG---KSP 1022
+G+ + SG G S G+ S + S RK G +S
Sbjct: 681 GSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740
Query: 1023 SHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQ 1082
H SS+ + GS S S+G + G P ++ G+ G SSH Q
Sbjct: 741 QHGSSSG-LSSSYGQHGSGSHQSSGHGRQGSGSGHSPS-----RVRHGSSS-GHSSSHGQ 793
Query: 1083 YTSSGSVSSS----------------------------GSKSHH--------SHSSSSSS 1106
+ S S SSS GS S H S S SSS
Sbjct: 794 HGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS 853
Query: 1107 SASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSP-ITKHGLSS 1165
S S S G S + + SGS QS Q G G SP +HG S
Sbjct: 854 SGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGS 913
Query: 1166 GSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPI 1225
G SS+ + G S + K + S GS S G+ ++S
Sbjct: 914 GRSSSSGR-HGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQ 972
Query: 1226 SSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSS------SGSS 1279
S GS S SG + S G G GS S ++P S S S SS SGS
Sbjct: 973 HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSG 1032
Query: 1280 MSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL-KHGVVTSGPGGEDPLDGQMGVSTNSSS- 1337
SSS+ + S G S + S + +HG G GQ G ++ SS
Sbjct: 1033 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG----SSSGHSSTHGQHGSTSGQSSS 1088
Query: 1338 ---HPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIII 1394
H SS + S G+ +S + S SG S ++ S S+ S G
Sbjct: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG------ 1142
Query: 1395 SKHDGGS-PSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKS 1453
+H GS S + GESSG G +SS S GS H G H
Sbjct: 1143 -RHGSGSGRSSSSGQHGSGLGESSGFG--HHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1199
Query: 1454 PAYTPQNLDSESESGSS 1470
+ + S SGSS
Sbjct: 1200 SGQSSRGERHGSSSGSS 1216
Score = 97.4 bits (241), Expect = 9e-20
Identities = 175/696 (25%), Positives = 241/696 (34%), Gaps = 83/696 (11%)
Query: 810 SSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDL 869
SSSSG S S F ++E+ + +GS S S H G
Sbjct: 1385 SSSSGRHGSGSGQSSGF--GHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSG------- 1435
Query: 870 LNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTV 929
QS GE + S SG + + S + +LG G +G++ + +
Sbjct: 1436 -----QSSRGERH---GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSG 1487
Query: 930 DFSIISVAGKALAPADLMEHHSGSQGPLLT----TGDLGKEKTQKRVKEGNGTSNSTLSG 985
S + +P S S+GP + + LG +++ G G S+
Sbjct: 1488 -----SGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH 1542
Query: 986 PGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS-NRPFTPPTSTGGSKSPG 1044
+ G S S+ G+ + G S SS R + + G G
Sbjct: 1543 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1602
Query: 1045 SAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSK--SHHSHSS 1102
S R G + + G+ + G+ S + SS SSS S+ S HSS
Sbjct: 1603 SGSRQSPSYGRHGSGSGRSSSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSS 1661
Query: 1103 SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPIT-KH 1161
S SG+ SS+ E SS SSS Y G SGS QS + G G SP +H
Sbjct: 1662 GYGQHGSRSGQ--SSRGERHGSSSRSSSRYGQHG-SGSRQSSGHGRQGSGSGQSPSRGRH 1718
Query: 1162 GLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKA 1221
G G SS SH + GS + +S P S
Sbjct: 1719 GSGLGHSS------------------------SHGQHGSGSGR-SSSRGPYESRSGHSSV 1753
Query: 1222 KSPISSGSG-GSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS--SSGS 1278
SGSG S S S SG S G S S T S T SSS SGS
Sbjct: 1754 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS 1813
Query: 1279 SMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSS- 1337
S SSS Q GS G+SPSR + S + +G SG G G+ G + SS
Sbjct: 1814 SQSSSYGQQGSGSGQSPSRGRHGSGSG--HSSSYGQHGSGSGWSSS-SGRHGSGSGQSSG 1870
Query: 1338 --HPMSSKHNMSG------GEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGV 1389
H SS SG G + +S S+ G SS +S S +G
Sbjct: 1871 FGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGS 1930
Query: 1390 AKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPS 1449
+ + G + + G SG+ S +YG P SGS RG
Sbjct: 1931 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ--------SSSYG-PYGSGSGWSSSRGPYE 1981
Query: 1450 HSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDG 1485
+ + +S S S + + SS G
Sbjct: 1982 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 2017
Score = 95.9 bits (237), Expect = 3e-19
Identities = 175/684 (25%), Positives = 242/684 (35%), Gaps = 111/684 (16%)
Query: 847 GSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTL 906
GS S SP + G +P S SG S G++ F S + +
Sbjct: 1119 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1178
Query: 907 GVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKE 966
G +G + G + G + E H S G G G
Sbjct: 1179 SYSQHGSGSGHSSGYGQH-------------GSRSGQSSRGERHGSSSGSSSHYGQHGSG 1225
Query: 967 KTQK--RVKEGNGTSNSTL-----SGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
Q ++G+G+ +S SG G S G+ S G+S + P ++
Sbjct: 1226 SRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHG---SGSGRSSSRGPYESRSGHSS 1282
Query: 1020 KSPSHSSSNRPFTPPTSTG-GSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPS 1078
H S + + + G GS S G+ + G ++ + G+ S
Sbjct: 1283 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST--------FDQEGSSTGQSS 1334
Query: 1079 SHSQYTSSGSVSSSG------------SKSHHS----HSSSSSSSASTSGKMKSSKSEGS 1122
S+ + SGS SSG S+ H HSSS S SG SS GS
Sbjct: 1335 SYG-HRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 1393
Query: 1123 SSSKLS------SSMYSSQG----SSGSSQSKNSSQSGGKPG-SSPITKHGLSSGSSSTK 1171
S + S SS + S G SGS S + Q G + G SS +HG SSGSSS+
Sbjct: 1394 GSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS- 1452
Query: 1172 MKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPS-SKAKSPISSGSG 1230
G+ S SL H + GS + SP + G+ S + SP SGSG
Sbjct: 1453 ---YGQHGSGSRQSLG-------HGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG 1502
Query: 1231 GSHMSGTSSS-----SGMKSSSGLG----SSGSLSQKTPPSSNSCTASSSSFSSSGSSMS 1281
SSS SG SSGLG SG S S+S +S+ S S S
Sbjct: 1503 W------SSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1556
Query: 1282 SSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMS 1341
SS QHG+S G+S S + S ++ +G SG G+ P GQ G + S P
Sbjct: 1557 SSCGQHGASSGQSSSHGQHGSGSS--QSSGYGRQGSG-SGQSPGHGQRG--SGSRQSPSY 1611
Query: 1342 SKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGS 1401
+H G G+ S + S + S + +S + G S H G
Sbjct: 1612 GRH----GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG----SGHSSGY 1663
Query: 1402 PSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNL 1461
++ GE G R SS YG GS + G +P
Sbjct: 1664 GQHGSRSGQSSRGERHGSSSR----SSSRYGQ---HGSGSRQSSGHGRQGSGSGQSP--- 1713
Query: 1462 DSESESGSSIAEKSYQNSPSSDDG 1485
S GS + S S G
Sbjct: 1714 -SRGRHGSGLGHSSSHGQHGSGSG 1736
Score = 95.5 bits (236), Expect = 4e-19
Identities = 160/651 (24%), Positives = 227/651 (34%), Gaps = 87/651 (13%)
Query: 874 SQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSI 933
S+SG S SG + + S + +LG G +G++ + +
Sbjct: 962 SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSG---- 1017
Query: 934 ISVAGKALAPADLMEHHSGSQGPLLT----TGDLGKEKTQKRVKEGNGTSNSTLSGPGLD 989
S + P S S+GP + + LG +++ G G S+
Sbjct: 1018 -SGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
Query: 990 SKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS-NRPFTPPTSTGGSKSPGSAGR 1048
+ G S S+ G+ + G S SS R + + G GS R
Sbjct: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
Query: 1049 SQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSK--SHHSHSSSSSS 1106
G + + G+ + G+ S + SS SSS S+ S HSS
Sbjct: 1137 QSPSYGRHGSGSGRSSSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1195
Query: 1107 SASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPIT-KHGLSS 1165
S SG+ + GSSS SSS Y G SGS QS + G G SP +HG
Sbjct: 1196 HGSRSGQSSRGERHGSSSG--SSSHYGQHG-SGSRQSSGHGRQGSGSGHSPSRGRHGSGL 1252
Query: 1166 GSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPI 1225
G SS SH + GS + +S P S
Sbjct: 1253 GHSS------------------------SHGQHGSGSGR-SSSRGPYESRSGHSSVFGQH 1287
Query: 1226 SSGSG-GSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS--SSGSSMSS 1282
SGSG S S S SG S G S S T S T SSS+ SGSS SS
Sbjct: 1288 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS 1347
Query: 1283 SQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSS 1342
+HG+ G+SPSR +HG SG G GQ G + SS S
Sbjct: 1348 GYGRHGAGSGQSPSRG------------RHG---SGSGHSSSY-GQHGSGSGWSS--SSG 1389
Query: 1343 KHNMSGGEFQ--GKREKSDKDKSKVSTSGSSVDSSK----------KTSESKNVGSTGVA 1390
+H G+ G E S S + GS S ++S + GS+ +
Sbjct: 1390 RHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGS 1449
Query: 1391 KIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKN-YGSPLISGSTPKHERGSPS 1449
+H GS + +L SG G P + ++ GS S +P S
Sbjct: 1450 SSSYGQHGSGS-----RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWS 1504
Query: 1450 HSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500
S+ P +S S S + + ++ SS G + H +H
Sbjct: 1505 SSRGP------YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 1549
Score = 95.1 bits (235), Expect = 5e-19
Identities = 178/710 (25%), Positives = 256/710 (36%), Gaps = 126/710 (17%)
Query: 804 GTPLRDSSSSG-HSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDG 862
G+ R SSS G H ++ S Q ++ + + SPSS F
Sbjct: 391 GSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSS 450
Query: 863 VDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKG 922
P + S SGFG SG + S + ++ G G +G++ +G
Sbjct: 451 SS-GPYVSGSGYSSGFGHHESSSEHSSG----YTQHGSGSGHSSGHGQHGSRSGQSS-RG 504
Query: 923 NNQADTVDFSIISVAGKALAPADL--MEHHSGS-QGPLLTTG--DLGKEKTQKRVKEGNG 977
Q + S + + L H SGS Q P + G + G ++ G G
Sbjct: 505 ERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYG 564
Query: 978 TSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTST 1037
+ S+ GP +S G S + +S + + G S +H +++
Sbjct: 565 SGRSSSRGP-YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG------STS 617
Query: 1038 GGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSS------ 1091
G S S G G + G+ SSH Q+ S S SS
Sbjct: 618 GQSSSCGQHGATS------------------------GQSSSHGQHGSGSSQSSRYGQQG 653
Query: 1092 -----SGSKSHHS----HSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQ 1142
S S+ H HSSS S SG S+ GS S + S + S GS Q
Sbjct: 654 SGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS----GSGQ 709
Query: 1143 SKNSSQSG-GKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGG 1201
S SQ G G SS KHG SG SS + + G S L S S+ + G
Sbjct: 710 SSGYSQHGSGSSHSSGYRKHGSRSGQSS-RSEQHGSSSGL----------SSSYGQHGSG 758
Query: 1202 SDKLASPMKPVPGTPPS-SKAKSPISSG---SGGSHMSGTSSSSGMKS-SSGLGSSGSLS 1256
S + + + G+ S S+ + SSG S G H SGTS SS SG G +
Sbjct: 759 SHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFG 818
Query: 1257 QKTPPSSNSCTASSSSFSSSGSSMS--SSQNQHGSSKGKSPSRNKKPSLTAVIDKL-KHG 1313
Q + S +S GS+ SSQ +HGS+ G+S S + S + +H
Sbjct: 819 QHE-------SGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHE 871
Query: 1314 VVT---SGPG------GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSK 1364
+ SG G G+ P GQ G + S P +H G +S
Sbjct: 872 SASHHASGRGRHGSGSGQSPGHGQRG--SGSGQSPSYGRHGSGSG-------RSSSSGRH 922
Query: 1365 VSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQ 1424
S SG S K+S ++ G T +H GS + ++ G SG+ R +
Sbjct: 923 GSGSGQSSGFGHKSSSGQSSGYT--------QHGSGSGH---SSSYEQHGSRSGQSSRSE 971
Query: 1425 M-----ASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGS 1469
SS +YG GS + G H +P SGS
Sbjct: 972 QHGSSSGSSSSYGQ---HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1018
Score = 95.1 bits (235), Expect = 5e-19
Identities = 149/558 (26%), Positives = 197/558 (35%), Gaps = 103/558 (18%)
Query: 847 GSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTL 906
GS S SP+ G + S SG+ S SG + F S + +
Sbjct: 1823 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
Query: 907 GVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKE 966
G G +G + S G + E H S G ++ G+
Sbjct: 1883 GYTQHGSGSGHS-------------SSYEQHGSRSGQSSRGEQHGSSSG---SSSSYGQH 1926
Query: 967 KTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSS 1026
+ R G+G S G G P R R S G+S P G SS
Sbjct: 1927 GSGSRQSLGHGQHGS---GSGQSPSPS-RGRHGSGSGQSSSYGPY-------GSGSGWSS 1975
Query: 1027 SNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSS 1086
S P+ +G S G R G+ S + Q+ SS
Sbjct: 1976 SRGPY----ESGSGHSSGLGHRESRS----------------------GQSSGYGQHGSS 2009
Query: 1087 GSVSSSGSKSHHSHSSSSSSSAS------TSGKMKSSKSEGSSSSKLSSSMYSSQGSSGS 1140
S S +H H S+S S+S +SG+ S GS SS+ SS Y QGS GS
Sbjct: 2010 ----SGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ--SSGYGRQGS-GS 2062
Query: 1141 SQSKNSSQSGGKPGSSP-ITKHGLSSG--SSSTKMKPQGKPSSLMNPSLSKPNISPSHSR 1197
QS Q G SP +HG SG SSS + P SS S S S+S+
Sbjct: 2063 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122
Query: 1198 PPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQ 1257
GS + + + SS+ + S SG S G SG + SSG G GS S
Sbjct: 2123 HGSGSGHSSGYGQHGSRSGQSSRGERH-GSSSGSSSRYG-QHGSGSRQSSGHGRQGSGSG 2180
Query: 1258 KTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTS 1317
+P S SGS SSS QHGS G+S SR S +
Sbjct: 2181 HSP---------SRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRS------------- 2218
Query: 1318 GPGGEDPLDGQ----MGVSTNSSSHPMSSKHNMSGGEF---QGKREKSDKDKSKVSTSGS 1370
G + GQ G S+ S H S H S G+ G+ D++ S S S
Sbjct: 2219 ---GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275
Query: 1371 SVDSSKKTSESKNVGSTG 1388
+S+S + G G
Sbjct: 2276 HGQHGSGSSQSSSYGQQG 2293
Score = 87.0 bits (214), Expect = 1e-16
Identities = 146/561 (26%), Positives = 193/561 (34%), Gaps = 103/561 (18%)
Query: 847 GSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTL 906
GS S SP+ G + S SG+ S SG + F S + +
Sbjct: 2293 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
Query: 907 GVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKE 966
G G +G + + + + S G + + H L G G
Sbjct: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
Query: 967 KTQK----RVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADT----- 1017
Q R + G+G+ S+ P SR P G +++ +
Sbjct: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
Query: 1018 ---EGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMV 1074
G S HSS++ +++G S S G G S
Sbjct: 2473 YGQHGSSSGHSSTHGQHG--STSGQSSSCGQHGASS------------------------ 2506
Query: 1075 GKPSSHSQYTSSGSVSS------SGSKSHHSHSSSSSSS---------ASTSGKMKSSKS 1119
G+ SSH Q+ S S SS SGS H S S S SG+ SS
Sbjct: 2507 GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQ 2566
Query: 1120 EGSS-----------SSKLSSSMYSSQGSSGSSQSKNSSQSGGKPG-SSPITKHGLSSGS 1167
GS SS SS YS GS GS S Q G + G SS +HG SSGS
Sbjct: 2567 HGSGLGESSGFGHHESSSGQSSSYSQHGS-GSGHSSGYGQHGSRSGQSSRGERHGSSSGS 2625
Query: 1168 SST--KMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPI 1225
SS + + SS S SPS R G +S + G+ SS ++ P
Sbjct: 2626 SSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS-SRGPY 2684
Query: 1226 SSGSG-----GSHMSGTS---------SSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSS 1271
S G G H SG+ S SG S G S S T S T SS
Sbjct: 2685 ESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 2744
Query: 1272 SFS--SSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQM 1329
S+ SGSS SS +HG+ G+S L HG SG G+ GQ
Sbjct: 2745 SYGHRGSGSSQSSGYGRHGAGSGQS---------------LSHGRHGSG-SGQSSSYGQH 2788
Query: 1330 GVSTNSSSHPMSSKHNMSGGE 1350
G + SS S+H G+
Sbjct: 2789 GSGSGQSSG--YSQHGSGSGQ 2807
Score = 80.9 bits (198), Expect = 9e-15
Identities = 132/513 (25%), Positives = 189/513 (36%), Gaps = 59/513 (11%)
Query: 810 SSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDL 869
SSSSG S S F ++E+ + +GS S S H G
Sbjct: 2325 SSSSGRHGSGSGQSSGF--GHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSG------- 2375
Query: 870 LNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTV 929
QS GE + S SG + + S + +LG G +G++ + +
Sbjct: 2376 -----QSSRGERH---GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSG 2427
Query: 930 DFSIISVAGKALAPADLMEHHSGSQGPLLT----TGDLGKEKTQKRVKEGNGTSNSTLSG 985
S + +P S S+GP + + LG +++ G G S+
Sbjct: 2428 -----SGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH 2482
Query: 986 PGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS-NRPFTPPTSTGGSKSPG 1044
+ G S S+ G+ + G S SS R + + G G
Sbjct: 2483 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 2542
Query: 1045 SAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSK--SHHSHSS 1102
S R G + + G+ + G+ S + SS SSS S+ S HSS
Sbjct: 2543 SGSRQSPSYGRHGSGSGRSSSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSS 2601
Query: 1103 SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPIT--- 1159
S SG+ + GSSS SSS Y GS GS QS + G G SP
Sbjct: 2602 GYGQHGSRSGQSSRGERHGSSSG--SSSHYGQHGS-GSRQSSGHGRQGSGSGQSPSRGRH 2658
Query: 1160 -----------KHGLSSGSSSTKMKPQGK--PSSLMNPSLSKPNISPSHSRPPGGSDKLA 1206
+HG SG SS++ + + SS+ S S ++S+ GS
Sbjct: 2659 GSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFC 2718
Query: 1207 SPMKPVPGTPPSS----KAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPS 1262
S + + SS + S S S G SG+S SSG G GS SLS S
Sbjct: 2719 SQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY-GRHGAGSGQSLSHGRHGS 2777
Query: 1263 SNSCTASSSSFS--SSGSSMSSSQNQHGSSKGK 1293
+ SSS+ SGS SS +QHGS G+
Sbjct: 2778 GSG---QSSSYGQHGSGSGQSSGYSQHGSGSGQ 2807
Score = 63.5 bits (153), Expect = 2e-09
Identities = 111/518 (21%), Positives = 179/518 (34%), Gaps = 52/518 (10%)
Query: 804 GTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPS-------SDSPTN 856
G+ SS GH +S+ + S + + + + ++ + +G S S ++
Sbjct: 2332 GSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSS 2391
Query: 857 HFFHDGVDFNPDLLNSQSQSGFGEEYFDE----SSQSGDNDDFKGFASQALNTLGVPMLG 912
+ G L + Q SG G+ S SG + + + S + +
Sbjct: 2392 SYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYE 2451
Query: 913 GDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRV 972
+G + G+ ++ + S G + + H + G + G G Q
Sbjct: 2452 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSS 2511
Query: 973 KEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGK-SKDKPPKRKKADTEGKSPSHSSSNRPF 1031
+G+ +S SG G +S G S+ P + G+S S
Sbjct: 2512 HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 2571
Query: 1032 TPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSV-- 1089
+ G +S S + G + + G+ S S +S G
Sbjct: 2572 GESSGFGHHESSSGQSSSYSQHGSGSGH-----------SSGYGQHGSRSGQSSRGERHG 2620
Query: 1090 SSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSM--YSSQGSSGSSQSKNSS 1147
SSSGS SH+ S S +S G+ S + S + S + SS G GS ++SS
Sbjct: 2621 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 2680
Query: 1148 QS----------------GGKPGSSPITKHGLSSGS--SSTKMKPQGKPSSLMNPSLSKP 1189
+ G SS ++HG SG S + SS + S
Sbjct: 2681 RGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2740
Query: 1190 NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSG-----GSHMSGTSSSSGMK 1244
S S+ GS + + + G+ S + SGSG G H SG+ SSG
Sbjct: 2741 GQSSSYGHRGSGSSQSSGYGRHGAGSG-QSLSHGRHGSGSGQSSSYGQHGSGSGQSSGY- 2798
Query: 1245 SSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSS 1282
S G GS SN SS S+ S S +S
Sbjct: 2799 SQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTS 2836
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 100 bits (249), Expect = 1e-20
Identities = 220/1045 (21%), Positives = 373/1045 (35%), Gaps = 146/1045 (13%)
Query: 557 MSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGS 616
+ +T P ++ G L S + D E S++P L S Q + GG
Sbjct: 1039 VKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGR 1098
Query: 617 TIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSP 676
+ SSP + P+ G PML + + ++ F + S P NS G
Sbjct: 1099 SRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSR-FQSDSSSYPTVDSNSLLGQS 1157
Query: 677 RMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTP 736
R+E + K+ LPP++ Q++ FS P + + DTL TP
Sbjct: 1158 RLE------TAESKEKMALPPQEDA-TASPPRQKDKFSPFPVQDRPESSL-VFKDTLRTP 1209
Query: 737 --HITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLP 794
+ A S T P + +V S + G ++ + S++ E ++
Sbjct: 1210 PRERSGAGSSPETKEQNSALPTSSQDEELMEVVE-KSEEPAGQILSHLSSELKEMSTSNF 1268
Query: 795 STS---DDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSS 851
+S ++ PA+ L S S ++ S +A + G P
Sbjct: 1269 ESSPEVEERPAVSLTLDQSQSQASLEAVEVPS------------------MASSWGGP-- 1308
Query: 852 DSPTNHFFHDGVDFNPDLLNSQ-SQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPM 910
HF + + +L NS ++ FG +S + GF+S+ L P
Sbjct: 1309 -----HFSPE----HKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF 1359
Query: 911 LGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQK 970
L NQ +T D S+ D+ E + S +G E +
Sbjct: 1360 L------------NQLET-DPSL-----------DMKEQSTRS------SGHSSSELSPD 1389
Query: 971 RVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRP 1030
V++ +SN ++S P LD+ P RTPS + S P+ K +G + S +R
Sbjct: 1390 AVEKAGMSSNQSISSPVLDAVP----RTPSRERSSSASSPEMK----DGLPRTPSRRSRS 1441
Query: 1031 FTPPTSTGGSKSPGSAGRSQTPPGVA-TPPIPK------ITIQIPKGTVMVGKPSSHSQY 1083
+ P GS +P S + PG+ P P + PK +P S S
Sbjct: 1442 GSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPS 1501
Query: 1084 TSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQS 1143
+ + + S S SS + + +S SS +L +S S S
Sbjct: 1502 SPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDS 1561
Query: 1144 KNSSQSGGKPGSSPITKHGLSSGS----SSTKMKPQGKPSSLMNPSLSKPNISPSHSRPP 1199
S++ + +P+ + S S S +++ P+ S KP +P R
Sbjct: 1562 SPDSKAKTR---TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAP---RAQ 1615
Query: 1200 GGSDKLASPMKPVPGTPP-------SSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSS 1252
GSD P P P P SSK + P GS + S + G SS
Sbjct: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675
Query: 1253 --GSLSQKTPPSSNSCTASSS-SFSSSGSSMSSSQNQHGSSKGKSPSRNKK-PSLTAVID 1308
+TPP S +S + + S S S + ++ ++P R+++ PS+++
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735
Query: 1309 KLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTS 1368
K P + ++ P + + +REK+ + + S
Sbjct: 1736 AEKSRSSRRRRSASSP---RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR-DRS 1791
Query: 1369 GSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASS 1428
GSS +S++ S++ + + GGS Q+ +S R + +
Sbjct: 1792 GSSQSTSRRRQRSRS------RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP 1845
Query: 1429 KNYGSPLISGSTP-----KHERGSP-SHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSS 1482
S ++P R SP +H +S + TP L S S S + S + S S
Sbjct: 1846 PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP--LISRRRSRSRTSPVSRRRSRS- 1902
Query: 1483 DDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKS-----P 1537
T ++ + + + R R R +++S S P + +S P
Sbjct: 1903 ----------RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPP 1952
Query: 1538 ISSDQSLSMTSNTILSADRPSRLSP 1562
++ +S S T R SR SP
Sbjct: 1953 VTRRRSRSRTPPVTRRRSR-SRTSP 1976
Score = 89.0 bits (219), Expect = 3e-17
Identities = 119/503 (23%), Positives = 195/503 (38%), Gaps = 47/503 (9%)
Query: 996 SRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGR-----SQ 1050
SRTP+ P+ A + + + + P P + G+++P + S
Sbjct: 2259 SRTPAAAAAMNLASPRTAVAPS---AVNLADPRTPTAPAVNLAGARTPAALAALSLTGSG 2315
Query: 1051 TPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAST 1110
TPP A P T Q P +VG S+H+ + V+ +GS++ +++ + ++ T
Sbjct: 2316 TPPTAANYPSSSRTPQAPASANLVGPRSAHA----TAPVNIAGSRT----AAALAPASLT 2367
Query: 1111 SGKMKSSKSEGS-SSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSS 1169
S +M + S + +S ++ S Y S + ++S P + ++ S
Sbjct: 2368 SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP 2427
Query: 1170 TKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGS 1229
+ Q SL+ P+ +P SP S S L + PV G+ S ++ S
Sbjct: 2428 SSRMGQAPSQSLLPPAQDQPR-SPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486
Query: 1230 GGSHMSGTS--------SSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMS 1281
G H S S G +S S P+ ++SSSS SSS SS S
Sbjct: 2487 AGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSS 2546
Query: 1282 SSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMS 1341
SS + SS G S S ++ SL + V + P ++ V P
Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE------AVREGRPPEPTP 2600
Query: 1342 SKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGS 1401
+K ++ +S S S+S SS SS +S S + S+ + S S
Sbjct: 2601 AK----------RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 1402 PSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNL 1461
P+ L KP +S + P S++ P+ S + SP + P+ P
Sbjct: 2651 PAKPGPQALPKP--ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708
Query: 1462 D---SESESGSSIAEKSYQNSPS 1481
D S SE GS ++ SPS
Sbjct: 2709 DQQSSSSERGSRRGQRGDSRSPS 2731
Score = 83.2 bits (204), Expect = 2e-15
Identities = 146/655 (22%), Positives = 223/655 (34%), Gaps = 84/655 (12%)
Query: 959 TTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDS-----KPGKRSRTPSNDGKSKDKPPKRK 1013
TT G+ + + G G ++ S PG S P ++ PS+ + KDK K K
Sbjct: 288 TTALAGRSPSPASGRRGEG--DAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEK 345
Query: 1014 KADTEGKSPSHSSSNRPFTPPTST-----GGSKSP-GSAGRSQ---TPPGVATP----PI 1060
A SP SS+ PT GGS P + SQ PP A+P
Sbjct: 346 SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405
Query: 1061 PKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSK--------SHHSHSSSSSSSASTSG 1112
PK ++P+ + P S S SSS SH SSS +S + G
Sbjct: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHG 465
Query: 1113 KMKSSKSEG-SSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTK 1171
+ K KS + S ++ S + G S+S+ ++ G SP + S+
Sbjct: 466 RAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRS 525
Query: 1172 MKPQ--GKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGS 1229
PQ G+ S P S+ + R S + P T S++++P G
Sbjct: 526 RSPQRRGRSRSPQRPGWSRSRNTQRRGR--SRSARRGRSHSRSPATRGRSRSRTPARRGR 583
Query: 1230 GGSHMSGTSSSSGMKSSSGLGSS------GSLSQKTPPSSNSCT--------ASSSSFSS 1275
S S + S G +TP S T S S
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARR 643
Query: 1276 SGSSMSSSQNQHGSSKGKSP-----SRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQ-- 1328
SG S S + + G S+ ++P SR++ P+ + + + P G+
Sbjct: 644 SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSR 703
Query: 1329 -MGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGST 1387
+ SH + + G ++ KS + + S S SS + K S+ S
Sbjct: 704 SRSLVRRGRSHSRTPQRRGRSGSSSERKNKS-RTSQRRSRSNSSPEMKKSRISSRRSRSL 762
Query: 1388 GVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGS 1447
SP KAK L SG P+ S + P+ R
Sbjct: 763 ------------SSPRSKAKSRLSLRRSLSGSSPCPKQKSQ----------TPPRRSRSG 800
Query: 1448 PSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKV 1507
S K+ + TP S S SS K +PS P K K ++
Sbjct: 801 SSQPKAKSRTPPR---RSRSSSSPPPKQKSKTPSRQSHSSSSPH---PKVKSGTPPRQGS 854
Query: 1508 KDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRLSP 1562
+ ++ ++ P+ KS S S S +S + + P R SP
Sbjct: 855 ITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP 909
Score = 81.6 bits (200), Expect = 5e-15
Identities = 137/518 (26%), Positives = 208/518 (40%), Gaps = 66/518 (12%)
Query: 990 SKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRP----FTPPTSTGGSKSPGS 1045
S+P +SRTP +S PP ++K+ T + SSS P TPP G SP +
Sbjct: 802 SQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ-GSITSPQA 860
Query: 1046 AGRSQTPPG---VATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSS 1102
+S TP + P P++ + P S+++ SGS S KS
Sbjct: 861 NEQSVTPQRRSCFESSPDPELKSRTP------------SRHSCSGS-SPPRVKSSTPPRQ 907
Query: 1103 SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHG 1162
S S S+S K+K+ S S SSS S+ +S ++ ++ S S S +
Sbjct: 908 SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRY 967
Query: 1163 LSSGSSS--TKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSK 1220
SGSSS TK+KP+ P + S+S P PPG S L+ P P K
Sbjct: 968 SHSGSSSPDTKVKPETPPRQSHSGSIS-PYPKVKAQTPPGPS--LSGSKSPC----PQEK 1020
Query: 1221 AKSPISSGSGGSHMSGTSSSSGMKSSSGLGSS----GSLSQK----TPPSSNSCTAS--- 1269
+K + GS S +G+KSS+ G S SL K T P S T+S
Sbjct: 1021 SKDSLVQSCPGS----LSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEV 1076
Query: 1270 --SSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDG 1327
S S S S S S + + G S+ SP D+ + G P
Sbjct: 1077 RQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSP--E 1134
Query: 1328 QMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGST 1387
Q ++SSS+P +++ G R ++ + K K++ D++ K+ S
Sbjct: 1135 QSRFQSDSSSYPTVDSNSLLG----QSRLETAESKEKMALPPQE-DATASPPRQKDKFSP 1189
Query: 1388 GVAKIIISKHDGGSPSIKAKVTLQ-KPGESSGEGLRPQMASSKNYGSPLISGSTPKHERG 1446
D S+ K TL+ P E SG G P+ +K S L + S +
Sbjct: 1190 ------FPVQDRPESSLVFKDTLRTPPRERSGAGSSPE---TKEQNSALPTSSQDEELME 1240
Query: 1447 SPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDD 1484
S+ PA Q L S ++ ++++SP ++
Sbjct: 1241 VVEKSEEPA--GQILSHLSSELKEMSTSNFESSPEVEE 1276
Score = 80.9 bits (198), Expect = 9e-15
Identities = 139/601 (23%), Positives = 223/601 (37%), Gaps = 71/601 (11%)
Query: 995 RSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPG 1054
RSRTP+ G+S+ + P R+ + ++P+ +R TP S+S GRS +
Sbjct: 659 RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHS--- 715
Query: 1055 VATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKM 1114
TP + G+ K S + S S SS K S S S +S K
Sbjct: 716 -RTP-----QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKA 769
Query: 1115 KS------SKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSS 1168
KS S S S K S + SGSSQ K S+ T S SS
Sbjct: 770 KSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR----------TPPRRSRSSS 819
Query: 1169 STKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKA---KSP- 1224
S K + K S + S S P+ PP + SP P ++ SP
Sbjct: 820 SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPP-RQGSITSPQANEQSVTPQRRSCFESSPD 878
Query: 1225 --ISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTA----SSSSFSSSGS 1278
+ S + H SS +KSS+ S S S P + + S S SS
Sbjct: 879 PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP 938
Query: 1279 SMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDP-LDGQMGVSTNSSS 1337
S +S+ S+ SP N + L + + H +S P + S + S
Sbjct: 939 SRVTSRTTPRRSRSVSPCSNVESRL---LPRYSHSGSSSPDTKVKPETPPRQSHSGSISP 995
Query: 1338 HPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGS-----SVDSSKKTSESKNVGSTGVAKI 1392
+P G G + ++KSK S S S+ + K+S GV+ +
Sbjct: 996 YPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSL 1055
Query: 1393 IIS---------KHDGGSPSIK----AKVTLQKPGESSGEGLRPQMASSKNYGSPLISGS 1439
+ + D SP ++ +LQ ++S +G R + +S + L S S
Sbjct: 1056 QLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPV---TELASRS 1112
Query: 1440 TPKHERGSPSHS------KSPAYTPQNLDSES----ESGSSIAEKSYQNSPSSDDGIRPL 1489
+ +RG S S SP + DS S +S S + + + + S + P
Sbjct: 1113 PIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPP 1172
Query: 1490 PEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSN 1549
E +T + K + +DR +D ++ + SP + +Q+ ++ ++
Sbjct: 1173 QEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTS 1232
Query: 1550 T 1550
+
Sbjct: 1233 S 1233
Score = 79.7 bits (195), Expect = 2e-14
Identities = 93/343 (27%), Positives = 135/343 (39%), Gaps = 45/343 (13%)
Query: 983 LSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKS 1042
LSG L S S G++ R ++ T +PS S P S+ ++
Sbjct: 2375 LSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQA 2434
Query: 1043 PGSAGRSQTPPGVATP--PIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKS--HH 1098
P +S PP P P+P + + P + SQ SSG+V+++ S + H+
Sbjct: 2435 PS---QSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHN 2491
Query: 1099 S----------HSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQ 1148
HS AST + S+ + + + SS SS SS SS S +SS
Sbjct: 2492 GMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSS 2551
Query: 1149 SGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASP 1208
S GSS G SS ++P+ + +P+ + P + RPP
Sbjct: 2552 SSSSSGSSSSDSEG-----SSLPVQPEVALKRVPSPTPA-PKEAVREGRPP--------- 2596
Query: 1209 MKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTA 1268
TP K +S SS S S S +SSSS SSS SS SS+S ++
Sbjct: 2597 ----EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---------SSSSSSS 2643
Query: 1269 SSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLK 1311
SSSS S + + S K P + S ID L+
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLR 2686
Score = 77.4 bits (189), Expect = 1e-13
Identities = 110/407 (27%), Positives = 153/407 (37%), Gaps = 59/407 (14%)
Query: 934 ISVAGK----ALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLD 989
+++AG ALAPA L S P L+ +L + E + S P LD
Sbjct: 2350 VNIAGSRTAAALAPASLT---SARMAPALSGANLTSPRVPLSAYE---RVSGRTSPPLLD 2403
Query: 990 SKPGKRSRTPSNDGKSKDKPPKRKKADTE--GKSPSHS----SSNRPFTP---------- 1033
RSRTP + +R + + G++PS S + ++P +P
Sbjct: 2404 RA---RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 2460
Query: 1034 -----PTSTGGSKS---------PGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
T GS+S SAG V P +P + P + +PS+
Sbjct: 2461 CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520
Query: 1080 HS--QYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGS 1137
+ Q SSS S S S SSSSSSS+S+S SS SS + + +
Sbjct: 2521 LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVP 2580
Query: 1138 SGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSR 1197
S + K + + G P +P + SS SSS+ SS + S S + S S S
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 1198 PPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS- 1256
S SP KP P P K SP G S S K L S SLS
Sbjct: 2641 SSSSSSSSPSPAKPGPQALP--KPASPKKPPPGERR-----SRSPRKPIDSLRDSRSLSY 2693
Query: 1257 ---QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKK 1300
++ PS S SS S S + Q G S+ S R ++
Sbjct: 2694 SPVERRRPSPQ---PSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRE 2737
Score = 77.0 bits (188), Expect = 1e-13
Identities = 227/1035 (21%), Positives = 355/1035 (34%), Gaps = 160/1035 (15%)
Query: 616 STIGSSPTPPHHTP-PPVSSMAGNTKNHPMLMNLLKDNPAQDFST---LYGSSPLERQNS 671
S GSSP P + PP S +G+++ P + ++ S+ S RQ+
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQ--PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSH 835
Query: 672 SSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTAD 731
SS SP ++ SG T ++ S P+ Q+ +R F D + + T
Sbjct: 836 SSSSPHPKVKSG---TPPRQGSITSPQA-NEQSVTPQRRSCFESSPDPELK----SRTPS 887
Query: 732 TLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRMV---RLSSSDSIGPDVTDILSDIAE 788
+P + STPP P PQP ++ ++ + S S S P + + S
Sbjct: 888 RHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP 947
Query: 789 EASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGS 848
S+ S + + P R S S S T + ++ + + A
Sbjct: 948 RRSRSVSPCSNVESRLLP-RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPG 1006
Query: 849 PS-----SDSPTNHFFHDGVDFNPDLLN----SQSQSGFGEEYFDESS-----QSGDNDD 894
PS S P V P L+ +S + GE YF SS QS + D
Sbjct: 1007 PSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD 1066
Query: 895 FKGFASQ---ALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHS 951
+ S + P L + + G +++ + + +A ++ D E
Sbjct: 1067 HRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSS---PVTELASRSPIRQDRGEF-- 1121
Query: 952 GSQGPLLTTGDLGKEKTQKRVKEGNGT-----SNSTLSGPGLDSKPGKRSRTPSNDGKSK 1006
S P+L + G Q R + + + SNS L L++ K +
Sbjct: 1122 -SASPMLKS---GMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDAT 1177
Query: 1007 DKPPKRKKADTEGKSPSHSSSNRPF-----TPPTS-TGGSKSPGSAGRSQTPPGVATPPI 1060
PP++K + S+ F TPP +G SP + ++ P
Sbjct: 1178 ASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALP------- 1230
Query: 1061 PKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSE 1120
S + S + SH SS STS S + E
Sbjct: 1231 ---------------TSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVE 1275
Query: 1121 GSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSS 1180
+ L+ SQ S + + + + S G P SP K +S + G P
Sbjct: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHK---ELSNSPLRENSFGSPLE 1332
Query: 1181 LMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPS--SKAKSPISSGSGGSHMSGTS 1238
N ++ S + L P T PS K +S SSG S +S +
Sbjct: 1333 FRNSGPLGTEMNTGFSSEV--KEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDA 1390
Query: 1239 -SSSGMKSSSGLGSSG-SLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPS 1296
+GM S+ + S +TP S +ASS S +++ GSS G
Sbjct: 1391 VEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDG 1450
Query: 1297 RNKKPSLTAVIDKLKHGVVTSGPGGED-PLDGQMGVSTNSSS--------HPMSSKHNMS 1347
+ PS +H + S PG +D P G S SS P + S
Sbjct: 1451 -SGTPS--------RHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPS 1501
Query: 1348 GGEFQGK-----REKSDKDKS------------KVSTSGSSVDSSKKTSESKNVGSTGVA 1390
E K RE+S + S + S SGSS + K S S S
Sbjct: 1502 SPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERS---- 1557
Query: 1391 KIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMAS--------SKNYGSPLISG---S 1439
SP KAK T + S G P++ S S++ SP + +
Sbjct: 1558 ------ESDSSPDSKAK-TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRA 1610
Query: 1440 TPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKK 1499
P+ + GS S + A P+ L S SGSS K SP PE+ +
Sbjct: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSS--SKGRGPSPEGSSSTESSPEHPPKSRTA 1668
Query: 1500 HKKEKKKVKDKDRDRDRDKDRD---------------KKKSHSIKPESWSKSPISSDQSL 1544
+ + + K + R + R + +S S PE+ S++P +S
Sbjct: 1669 RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSP 1728
Query: 1545 SMTSNTILSADRPSR 1559
S++S R SR
Sbjct: 1729 SVSSPEPAEKSRSSR 1743
Score = 71.6 bits (174), Expect = 6e-12
Identities = 129/610 (21%), Positives = 220/610 (36%), Gaps = 93/610 (15%)
Query: 966 EKTQKRVKEGNGTSNSTLSGPGLDS---------------KPGKRSRTPSNDGKSKDKPP 1010
EK +R++ G S+S + G D KP R S+ K
Sbjct: 129 EKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQK 188
Query: 1011 KRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKG 1070
K+KK G+ SS R SK S++ P PK
Sbjct: 189 KKKKKKDRGRRSESSSPRR-----ERKKSSKKKKHRSESESKKRKHRSPTPK-------- 235
Query: 1071 TVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSS 1130
K S + ++ KS +H S+S+ SAS+S + S S+ +++
Sbjct: 236 ----SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR-------SRSRSAAA 284
Query: 1131 MYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPN 1190
+ +G S S S + G G +P ++ G +S +P ++ PS
Sbjct: 285 KTHTTALAGRSPSPASGRRG--EGDAPFSEPGTTS-----TQRPSSPETATKQPS----- 332
Query: 1191 ISPSHSRPPGGSDKLASPMKPVP---GTPPSSKAKSP-ISSGSGGSHMSGTSSSSGMKSS 1246
SP + +K A+ P P T P A +P ++ GGS ++ +
Sbjct: 333 -SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPV 391
Query: 1247 SGLGSSGSLSQKTPPSS-NSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTA 1305
+ + ++PP S SSSS SS S + ++H SS +SP P
Sbjct: 392 NPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPG--- 448
Query: 1306 VIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKV 1365
H ++S P ++ G+ S SH S + S KR +S +S+
Sbjct: 449 -----SHREISSSPTSKNRSHGR-AKRDKSHSHTPSRRMGRSRSPATAKRGRS---RSRT 499
Query: 1366 STS-GSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQ 1424
T G S S + S++ G ++ + SP Q+PG S +
Sbjct: 500 PTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSP--------QRPGWS-------R 544
Query: 1425 MASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPS--- 1481
+++ G + H R + +S + TP S S + +S +P+
Sbjct: 545 SRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPAR-RGRSRSRTPARRRSRSRTPTRRR 603
Query: 1482 --SDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRD--RDKDRDKKKSHSIKPESWSKSP 1537
S R S ++ + + V+ + R R R R + ++ + + S S++P
Sbjct: 604 SRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTP 663
Query: 1538 ISSDQSLSMT 1547
+S S T
Sbjct: 664 ARRGRSRSRT 673
Score = 65.5 bits (158), Expect = 4e-10
Identities = 85/374 (22%), Positives = 141/374 (37%), Gaps = 39/374 (10%)
Query: 943 PADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNG-------TSNSTLSGPGLDSKPGK- 994
P L+ S S+ P K+K + R E + +S +SK K
Sbjct: 170 PYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKH 229
Query: 995 RSRTPSNDGKSKDKPPKRKKADTEGKSP--SHSSSNRPFTPPTSTGGSKSPGSAGRSQTP 1052
RS TP + KSKDK KR ++ T +H S++ + T S+S +A ++ T
Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTT 289
Query: 1053 PGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSG 1112
P P + + ++ G+ S+ S + + SS
Sbjct: 290 ALAGRSPSP----------ASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKD 339
Query: 1113 KMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK-NSSQSGGKP---GSSPITKHGLSSGSS 1168
K K E S++ S SS G + + + + GG P ++P+++ ++ S
Sbjct: 340 K---DKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE 396
Query: 1169 STKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSG 1228
++ + + P S P S S S PP SP SS +SP +
Sbjct: 397 ASPTRDRSPPKS----PEKLPQSSSSESSPP-------SPQPTKVSRHASSSPESPKPAP 445
Query: 1229 SGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHG 1288
+ GSH +SS + S G S PS + S + + G S S + + G
Sbjct: 446 APGSHREISSSPTSKNRSHGRAKRDK-SHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG 504
Query: 1289 SSKGKSPSRNKKPS 1302
S+ +SP + S
Sbjct: 505 HSRSRSPQWRRSRS 518
Score = 63.9 bits (154), Expect = 1e-09
Identities = 125/636 (19%), Positives = 227/636 (35%), Gaps = 80/636 (12%)
Query: 963 LGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSK------------DKPP 1010
LG +T V + G S + GPG +R+ P N +S+ +PP
Sbjct: 2139 LGSSRTPMSVLQQAG--GSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPP 2196
Query: 1011 KRKKADTEGKSPSHSSSNRPF----TPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQ 1066
A S + P T P + S+ P ++ + TP IP
Sbjct: 2197 PSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNL 2256
Query: 1067 IPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSS--SASTSGKMKSSKSEGSSS 1124
T + + ++ + S+ + ++ + + A T + + GS +
Sbjct: 2257 ADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGT 2316
Query: 1125 SKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNP 1184
+++ SS + + S N ++P+ ++ ++ + P S+ M P
Sbjct: 2317 PPTAANYPSSSRTPQAPASANLVGPRSAHATAPVN---IAGSRTAAALAPASLTSARMAP 2373
Query: 1185 SLSKPNISPSHSRPPGGSDKLASPMKPV------PGTPPSSKAKSPISSGSGGSHMSGTS 1238
+LS N++ S P ++++ P TPPS+ ++S ++S S
Sbjct: 2374 ALSGANLT-SPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS------ 2426
Query: 1239 SSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRN 1298
SS +G + S S P + S+FS + + S+
Sbjct: 2427 ------PSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS------ 2474
Query: 1299 KKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKR--- 1355
L G V + +G + V H + S G Q
Sbjct: 2475 -----------LSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Query: 1356 -EKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQK-- 1412
+ + + +S S+S SS SS +S S + S+G + S +G S ++ +V L++
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSS---SDSEGSSLPVQPEVALKRVP 2580
Query: 1413 -----PGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESES 1467
P E+ EG P+ +K S S+ S S S S + + + S S S
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKRR---SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637
Query: 1468 GSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHS 1527
SS + S + + G + LP+ ++ K + + + K D RD + S+S
Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRD---SRSLSYS 2694
Query: 1528 -IKPESWSKSPISSDQSLSMTSNTILSADRPSRLSP 1562
++ S P DQ S + R SP
Sbjct: 2695 PVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
Score = 38.9 bits (89), Expect = 0.040
Identities = 128/708 (18%), Positives = 237/708 (33%), Gaps = 141/708 (19%)
Query: 995 RSRTPSNDGKSKDK-------------PPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSK 1041
RSRTP+ +S+ + PP ++ SP +R T P + S+
Sbjct: 1936 RSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSR 1995
Query: 1042 SPGS-----------------AGRSQTPPGV------ATPPIPKITIQIPKGTVMVGKPS 1078
S S RS+TPP + TP +P+ + + +
Sbjct: 1996 SRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSR 2055
Query: 1079 SHSQYTSSGS------------VSSSGSKSHHSHSSSSSSSASTSGK------MKSSKSE 1120
S + T+ G S+SGS S S S++ ++ + SG + SS+
Sbjct: 2056 SRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115
Query: 1121 GSSSSKLSSSMYSSQGSSGSSQSKNSSQSG----GKPGSSPITKHGLSSGSSSTKMKPQG 1176
S +S + S G + SS++ + G S + G P+
Sbjct: 2116 CFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPEN 2175
Query: 1177 KPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPG--------TPPSSKAKSPISSG 1228
S + +L+ ++ + P + LA+ M VP T P++ S I +
Sbjct: 2176 HAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA 2235
Query: 1229 SGGSHMSGTSSSSGMKSSSGLG----------------------SSGSLSQKTPPSSNSC 1266
S + ++ + + ++ L S+ +L+ P++ +
Sbjct: 2236 SAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAV 2295
Query: 1267 TASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKP----SLTAVIDKLKHGVVTSGPGGE 1322
+ + ++ +++S + + + PS ++ P S V + H G
Sbjct: 2296 NLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGS 2355
Query: 1323 DP--------------LDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTS 1368
G + S P+S+ +SG +++ + S
Sbjct: 2356 RTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPS 2415
Query: 1369 GSSVDSSKKTSESKNVGSTGVAKIIISKHD-----------GGSPSIKAKVTLQKPGESS 1417
S + S + S S +G ++ D S + A+ T +S
Sbjct: 2416 QSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSL 2475
Query: 1418 GEGLRPQMASSKNYGSPLIS---GSTPKHERGSPSHSK-----------SPAYTPQNLDS 1463
G SS + ++S P + G P S PA ++ S
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSS 2535
Query: 1464 ESESGSSIAEKSYQNSPSSDDG----------IRPLPEYSTEKHKKHKKEKKKVKDKDRD 1513
S S SS + S +S SS G + PE + ++ K+ + R
Sbjct: 2536 SSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP 2595
Query: 1514 RDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRLS 1561
+ + K++S S S S S SS S S +S++ S+ S S
Sbjct: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Score = 38.1 bits (87), Expect = 0.068
Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 22/174 (12%)
Query: 1399 GGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTP 1458
G P++ L + E E LR S +Y + GS+ +R + +K PA P
Sbjct: 113 GQRPAVTETHQLAELNEKKNERLRAAFGISDSY----VDGSSFDPQRRA-REAKQPAPEP 167
Query: 1459 Q---NLDSESESGSSIAEKSYQNSPSSDDGIR-----PLPEYS-TEKHKKHKKEKKKVKD 1509
+L ES S S K + D G R P E + K KKH+ E + K
Sbjct: 168 PKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKR 227
Query: 1510 KDRD-------RDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADR 1556
K R + +DK R + +S + P+S +S S S +S+T S R
Sbjct: 228 KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS-SSDTSRSRSR 280
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 89.7 bits (221), Expect = 2e-17
Identities = 235/1051 (22%), Positives = 374/1051 (35%), Gaps = 177/1051 (16%)
Query: 537 KKNLPPASSPGYGMTTGN-----NPMSGTTTP----TNTFPGGPITTLFNMSMSIKDRH- 586
+ L PASS G+ + +P S TTP T T P TT S H
Sbjct: 604 RTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 663
Query: 587 ----ESVGHGEDFSKVSQNPILTSLLQITGNGGSTIGSSPTPPHHTP--PPVSSMAGNTK 640
+ GH E + +P + + + ++ T +P ++++ G+T
Sbjct: 664 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 723
Query: 641 NHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKP 700
+ + ST + SSP + S + + G T +SR P
Sbjct: 724 TPGL----------SEASTTFYSSPRSPTTTLSPASMTSLGVGEEST----TSRSQPGST 769
Query: 701 KHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQ 760
H T + +S + +T PH T P T + +P
Sbjct: 770 -HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHT 828
Query: 761 PSIQRMVRLS-------------SSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPL 807
S +S G T +D+ EE++ PS+S +P
Sbjct: 829 TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPA 888
Query: 808 RDSSSSGHSQST---LFDSDVFQTNNNENP------------YTDPADLIADAAGSP--- 849
R ++S +ST L S T +P YT P DA SP
Sbjct: 889 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS--PDATLSPATT 946
Query: 850 -----SSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALN 904
S +S T+H G +S + S +E S G + S +
Sbjct: 947 TSSGVSEESSTSHS-QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTAS 1005
Query: 905 TLGVPMLGGDNGETKFKGNNQADTV---DFSIISVAGKALAPADLMEHHSGSQGPLLTT- 960
+LG T +T D +I S +A P HS S G L TT
Sbjct: 1006 SLG------QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT-----HS-STGSLHTTL 1053
Query: 961 -----GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKP--------GKRSRTPSND----- 1002
G ++ + +S++T S PG + P + S TP+
Sbjct: 1054 TPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS 1113
Query: 1003 ---GKSKDKPPKRKKADTEGKS--PSHSSSN----RPFTPPTSTGGSKS---PGS---AG 1047
G+S++ G + P+ S+++ P T P S+G +++ PGS AG
Sbjct: 1114 TTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAG 1173
Query: 1048 RSQTPPGVATPPIPKITIQIPKGTVMVG----KPSSHSQYTSSGSVSSSGSKSHHSHSSS 1103
S+ + P T P T G +SHS+ S+ + + GS + S
Sbjct: 1174 LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQE 1233
Query: 1104 SSSSASTSGKMKSSKSEGSSSSKL----SSSMYSSQGSSGSSQ-SKNSSQSGGKPGSSPI 1158
S++S S+ G ++ S GS+++ S++ +SS GS+ ++ N++ SG S+P+
Sbjct: 1234 STASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPV 1293
Query: 1159 TKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPS 1218
S+GS T + P G S ++ S + P D + +P P T +
Sbjct: 1294 HS---STGSPHTTLSPAG--------STTRQGESTTFQSWPSSKDTMPAP----PTTTSA 1338
Query: 1219 SKAKSPISSGSGGS----HMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS 1274
S S GS S H S +S++ G S S ++ T PS T S
Sbjct: 1339 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 1398
Query: 1275 SSG--SSMSSSQNQH--GSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMG 1330
S+ SS S+Q H SS S + S ++ + T+ E+P
Sbjct: 1399 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP------ 1452
Query: 1331 VSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVA 1390
S +SS +++ H G+ E+S S T+G + + T+ + ST
Sbjct: 1453 TSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAEST--- 1509
Query: 1391 KIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSH 1450
IS GS T PG S+ S+ Y S L+ T +
Sbjct: 1510 TFYISP---GSMETTLASTATTPGLSA--------KSTILYTSDLVGEPTTFYI------ 1552
Query: 1451 SKSPAYTPQNLDSESESGSSIAEKSYQNSPS 1481
S SP YT S S SG + ++ SPS
Sbjct: 1553 SPSPTYTTLFPASSSTSGLTEESTTFHTSPS 1583
Score = 82.4 bits (202), Expect = 3e-15
Identities = 217/1103 (19%), Positives = 367/1103 (33%), Gaps = 143/1103 (12%)
Query: 542 PASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQN 601
P S+ G++ + + PT+T TT ++ H G E + + N
Sbjct: 167 PGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTET-TLLPDN 225
Query: 602 PILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMA--GNTKNHPMLMNLLKDNPAQDFST 659
+ LL+ + + SS PH T P S G + + PA +T
Sbjct: 226 TTASGLLEAS----MPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTT 281
Query: 660 LYGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDS 719
S+ +E +S GSP ++ + + +S L E + + + + + D+
Sbjct: 282 ---SAFVEPSTTSHGSPSS--IPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT 336
Query: 720 QNPIFDVNMTADTLDTPHITPAPSQCST---PPTTYPQPVPHPQPSIQRMVRL-SSSDSI 775
+ + + T+ + T I+ APS S PT+Y H P SS +
Sbjct: 337 TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY-----HSSPGSTATTHFPDSSTTS 391
Query: 776 GPDVTDILSDIAEEASK---LPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNE 832
G S +++A+ LP+ S +G SSG ++T +E
Sbjct: 392 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 451
Query: 833 NPYT------DPADLIADAAGSPS--SDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFD 884
T PA ++ A+ + S S+ T G +S + G
Sbjct: 452 RSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTT 511
Query: 885 ESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPA 944
S G D T +P T G +Q T S AL+P
Sbjct: 512 SHSSPGSTD-----------TTLLP------ASTTTSGPSQESTTSHSSSGSTDTALSPG 554
Query: 945 DLMEHHSGSQGPLL--------------TTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDS 990
G + +T G + RV G+ +TLS P +
Sbjct: 555 STTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS-PASST 613
Query: 991 KPGKRS-----RTPSNDGKSKDKPPKRKKADTE---------GKSPS------------- 1023
PG + +T + PP A E G +P+
Sbjct: 614 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 673
Query: 1024 ------HSSSNRPFTPPTS-----------TGGSKSPGSAGRSQTPPGVATPPIPKITIQ 1066
HSS + T P+S T SPGS + P TP + + +
Sbjct: 674 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAS-- 731
Query: 1067 IPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSK 1126
T P S + S S++S G + S S S ++ S+ + G S
Sbjct: 732 ----TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE- 786
Query: 1127 LSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSL 1186
S+++YSS S + S + G P T H + + +T S L S
Sbjct: 787 -STTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 845
Query: 1187 SKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSS 1246
+ P SP AS +P T ++ ++ S +GT S ++
Sbjct: 846 AFPG-SP------------ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTT 892
Query: 1247 SGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAV 1306
SGL + S+ +P S+ + T S + S S S++ + +SP P+ T
Sbjct: 893 SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTT----FYTSPRSPDATLSPATTTS 948
Query: 1307 IDKLKHGVVT-SGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKV 1365
+ + S PG +T+ S ++ H+ S G + S +
Sbjct: 949 SGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS-SQGSTEATLSPGSTTASSL 1007
Query: 1366 STSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQM 1425
++ SS +E+ + + ++ S + T P S+ GL+ +
Sbjct: 1008 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEES 1067
Query: 1426 ASSKNYGS-----PLISGSTPKHERGSPSHSKSPAYTPQNLDSESES--GSSIAEKSYQN 1478
+ +++ S P G+T S ++ P+ TP S S + G S + +
Sbjct: 1068 TTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHS 1127
Query: 1479 SPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPI 1538
SP + G P S + + + S K ++ SP
Sbjct: 1128 SPGA-TGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 1186
Query: 1539 SSDQSLSMTSNTILSADRPSRLS 1561
S D +LS S T S S
Sbjct: 1187 SPDTTLSPASTTSSGVSEESTTS 1209
Score = 81.6 bits (200), Expect = 5e-15
Identities = 229/1016 (22%), Positives = 366/1016 (36%), Gaps = 129/1016 (12%)
Query: 543 ASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLF---NMSMSIKDRHESVGHGEDFSKVS 599
A SPG T + TT +N PG TTLF S I + V + +
Sbjct: 550 ALSPG-STTALSFGQESTTFHSN--PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 606
Query: 600 QNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDF-- 657
+P ++ + G + + P H TP P S+ + P F
Sbjct: 607 LSPASSTSPGLQGES-TAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPA 665
Query: 658 ----------STLYGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTE-- 705
ST++ SSP +SG+ S ++ + +SR+ P + T
Sbjct: 666 SSTTSGHSEKSTIFHSSP-----DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 720
Query: 706 -------DDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPH 758
+ +S + +MT+ + T ST T P
Sbjct: 721 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTT 780
Query: 759 PQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPA-IGTPL--RDSSSSGH 815
P S + SSS S + P+T PA T L DS++SG
Sbjct: 781 PGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGL 840
Query: 816 SQ-STLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQS 874
++ ST F T ADL ++ PSS T G +P S +
Sbjct: 841 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST------GTKLSP--ARSTT 892
Query: 875 QSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGG-DNGETKFKGNNQADTVDFSI 933
GE S S +++ G P T F + ++ S
Sbjct: 893 SGLVGESTPSRLSPS---------STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 943
Query: 934 ISVAGKALAPADLMEH------HSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPG 987
+ ++ H H+ + TT DL +E T +G+ + +TLS PG
Sbjct: 944 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGS--TEATLS-PG 1000
Query: 988 LDSKPGKRSRTPSNDGKSKDKPPKRKKADT------EGKSPSHSSS---NRPFTPPTSTG 1038
+ ++ + D DT E +P+HSS+ + TP +ST
Sbjct: 1001 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS 1060
Query: 1039 GSKSPGSAGRSQTPPGVATPPIPKITIQIPK--GTVMVGKPSSHSQYTSSGSVSSSGSKS 1096
S P T P P T P T +PSS S S ++ G +S
Sbjct: 1061 AGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLG-RS 1119
Query: 1097 HHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSS 1156
S + SS A+ + + S++S L +S SSGS+++ PGS+
Sbjct: 1120 EESTTVHSSPGATGTALFPTR----SATSVLVGEPTTSPISSGSTETT------ALPGST 1169
Query: 1157 PITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISP----SHSRPPGGSDKLASP-MKP 1211
T GLS S++ P+ ++L S + +S SHSRP G + A P
Sbjct: 1170 --TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP-GSTHTTAFPGSTT 1226
Query: 1212 VPGTPPSSKAK--SPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTA- 1268
+PG S A SP S+ + S S T+SS G +S++ S GS P + + +
Sbjct: 1227 MPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL 1286
Query: 1269 --SSSSFSSSGSSMSSSQNQHGSS--KGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDP 1324
+S+ SS S ++ + GS+ +G+S + PS + P
Sbjct: 1287 LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTM-----------PAPPTT 1335
Query: 1325 LDGQMGVSTNSSSHPMSSK--HNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESK 1382
+ +ST S P S+ H + G+ E+S +T SS ++ T
Sbjct: 1336 TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES-------TTVHSSPVATATTPSPA 1388
Query: 1383 NVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISG---S 1439
++G+ + + H SP + T+ P S+ G + +S + + IS +
Sbjct: 1389 RSTTSGLVEESTAYHS--SPG--STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST 1444
Query: 1440 TPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSD-DGIRPLPEYST 1494
T S+ SP ES + S +E+S + S D +GI PLP + T
Sbjct: 1445 TSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFT 1500
Score = 57.8 bits (138), Expect = 8e-08
Identities = 125/590 (21%), Positives = 217/590 (36%), Gaps = 98/590 (16%)
Query: 1035 TSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGS 1094
T++G S+ + S T +TP + + ++H + +S+ S S S
Sbjct: 8 TTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEES 67
Query: 1095 KSHHSHSSS------------------SSSSASTSGKMKSSKSEGSSS----SKLSSSMY 1132
K+ HS + S+ S +SG M+++ GS++ S+ S++ Y
Sbjct: 68 KASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFY 127
Query: 1133 SSQGS----------SGSSQSKNSSQSGGKPGSS-------PITKHGLSSGSSSTKMKPQ 1175
SS S + S S+ S+ S +PGS+ T GLS S+++ P
Sbjct: 128 SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPG 187
Query: 1176 GKPSSLMNPSLSKPNISPS----HSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGG 1231
++L S + ++ P HSRP L G +A P+ S +
Sbjct: 188 PTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGL---LEASMPVHSSTRS 244
Query: 1232 SHM----SGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSC-----TASSSSFSSSGSSMSS 1282
H +G+++ G ++ S ++ PP++ S T S S SS ++ S
Sbjct: 245 PHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHIS 304
Query: 1283 SQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSS 1342
+++ +S + + P T + TSG G E S +S++H +SS
Sbjct: 305 ARSTTSGLVEESTTYHSSPGSTQTM-HFPESDTTSGRGEEST------TSHSSTTHTISS 357
Query: 1343 KHNMSGGEFQGKREKSDKDKSKV--------STSGSSVDSSKKTSESKNVG-----STGV 1389
+ + + S +TSG S +S+ S G +
Sbjct: 358 APSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARST 417
Query: 1390 AKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPS 1449
+++ + S + T PG ++ GL + S+ + SP SP+
Sbjct: 418 TSVLLGESTTSPISSGSMETTALPGSTTTPGLSER--STTFHSSP-----------RSPA 464
Query: 1450 HSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRP-LPEYSTEKHKKHKKEKKKVK 1508
+ SPA T + SE + S S + D P L +ST H +
Sbjct: 465 TTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 524
Query: 1509 DKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPS 1558
++ SHS S S+D +LS S T LS + S
Sbjct: 525 PASTTTS-GPSQESTTSHS--------SSGSTDTALSPGSTTALSFGQES 565
Score = 37.0 bits (84), Expect = 0.15
Identities = 66/297 (22%), Positives = 110/297 (37%), Gaps = 52/297 (17%)
Query: 1233 HMSGTSSSSG-MKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSK 1291
H +S++SG + S+ S + ++ + PS+ + A +S SS GS+ ++ +
Sbjct: 2 HFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTIS 61
Query: 1292 GKSPSRNKKPS-----LTAVIDKLKHGVVTSGPGGEDPL-DGQMGVST--NSSSHPMSSK 1343
G+S S T V+ V G P+ G M + S++ P S+
Sbjct: 62 GRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSE 121
Query: 1344 HNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGST------------GVAK 1391
+ + F D S + S V TS S+ GST G+++
Sbjct: 122 KSTT---FYSSPRSPDTTHLPASMTSSGVSEESTTSHSR-PGSTHTTAFPGSTTMPGLSQ 177
Query: 1392 IIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQ--------------MASSKNYGSPLIS 1437
+ H P+ T PG ++ L P+ + S L+
Sbjct: 178 ESTASHSSPGPT----DTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLE 233
Query: 1438 GSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYST 1494
S P H S ++SP T S + G S ++ + PSS D RP P +T
Sbjct: 234 ASMPVH-----SSTRSPHTTLSPAGSTTRQGES---TTFHSWPSSKD-TRPAPPTTT 281
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 87.0 bits (214), Expect = 1e-16
Identities = 140/594 (23%), Positives = 215/594 (36%), Gaps = 82/594 (13%)
Query: 983 LSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKS 1042
+S P SKP + + D P T+ +P+ S P P TS S
Sbjct: 1 MSSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLV--PTKPATSRNSVMS 58
Query: 1043 PGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSS 1102
P S S++ +T P +PSS S+ S S S +
Sbjct: 59 PSS---SKSTKSTSTKRAPS------------NRPSSRSRVRSKARTPSRVS------TD 97
Query: 1103 SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHG 1162
+ +S AS + ++ + G+ S + G GS SK S PG I HG
Sbjct: 98 TRTSKASKASDVRCHQRRGTHSRG------RTPGRRGSRSSKRSPSRASTPGR--IRTHG 149
Query: 1163 LSSGSSSTKMKPQGKPSSLMNPSLSKP-------------NISPSHSRPPGGSDKLASPM 1209
G +S P + S +P N+S RPPGGS S
Sbjct: 150 ARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSE 209
Query: 1210 KPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTAS 1269
V TP ++K ++P +G S S S SS + S G + + S S T
Sbjct: 210 LAV--TPSTAKCQTP--TGIPSKEKSDNPSPS---SSRKVKSYGQMIIPSREKSYSPTEM 262
Query: 1270 SSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL-----KHGVVTSGPGGEDP 1324
SS S + + S+ Q S+ +SP R++ S ++ K +
Sbjct: 263 SSRVKSYNQASTRSRPQ-SHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
Query: 1325 LDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNV 1384
+ QMG + S SH N S +G+ ++ SK + S SSK E +
Sbjct: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSK---ERDHR 378
Query: 1385 GSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQM---------ASSKNYGSPL 1435
GS+ K + GSP+ + + + + + R + + S N
Sbjct: 379 GSSSPRKES-GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDC 437
Query: 1436 ISGSTPKHERG-----SPS----HSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGI 1486
+P R SP+ HS+S + S S S S + S SPS +
Sbjct: 438 SRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDH 497
Query: 1487 RPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPE---SWSKSP 1537
R S E+ + + K +D R R K+R +++S S E S S+SP
Sbjct: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSP 551
Score = 67.8 bits (164), Expect = 8e-11
Identities = 139/689 (20%), Positives = 233/689 (33%), Gaps = 79/689 (11%)
Query: 943 PADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSND 1002
PA L S + L + + ++ ST + ++P RSR
Sbjct: 29 PASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRV---- 84
Query: 1003 GKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGR---SQTPPGVATPP 1059
+SK + P R DT S +S R + ++PG G ++P +TP
Sbjct: 85 -RSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPG 143
Query: 1060 IPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKS 1119
+ P V P+S + GS S + S+ S S K KS +
Sbjct: 144 RIRTHGARPGMASRVRTPTSQQK----GSRGKSYGRPRTSNRERSDSQPRNLSK-KSYRP 198
Query: 1120 EGSSSSKLSSSM---------YSSQGSSGSSQSKNSSQSGGKPGSS------PITKHGLS 1164
G S SS + + G +S N S S + S P + S
Sbjct: 199 PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYS 258
Query: 1165 SGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSP 1224
S+++K + S+ P + SP SR G + S ++ S+A+S
Sbjct: 259 PTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS-GSQKRTHSRVRSHSWKRNHSRARSR 317
Query: 1225 ISSG---SGGSHMSGTSSSSGMKSSSGL----GSSGSLSQKTPPSSNSCTASSSSFSSSG 1277
G G H S S G + G S + S+ + + SSS
Sbjct: 318 TRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH 377
Query: 1278 SSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSS 1337
SS + + G S+ SP++ + S + +K + + P D S N +
Sbjct: 378 RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP--YKARDRSRSRSPNKAR 435
Query: 1338 HPMSSKHNMSGGEFQGKREKSD-KDKSKVSTSGSSVDSSKKTSESKN-----VGSTGVAK 1391
S+ + R + +D S+ + + D S+ S SK +GS +
Sbjct: 436 DCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKER 495
Query: 1392 IIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHS 1451
SPS + + + + R + S + +P ER S S
Sbjct: 496 ---DHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRR---QSRSPNKERDR-SQS 548
Query: 1452 KSPAYTPQNLDS----------------------ESESGSSIAEKSYQNSPSSDDGI-RP 1488
+SP+ ++ S +S S S + S SP+ G RP
Sbjct: 549 RSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRP 608
Query: 1489 LPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPES--WSKSPISSDQSLSM 1546
++ K K H + + K+ + + R ++ S S P S W +SP +
Sbjct: 609 R---ASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQN 665
Query: 1547 TSNTILSADRPSRLSPDFMIGEEDDDLMD 1575
+ + S+ PS +DD D
Sbjct: 666 RTPSKTSSHSPSTFPSGGQTLSQDDSQAD 694
Score = 43.5 bits (101), Expect = 0.002
Identities = 74/344 (21%), Positives = 119/344 (34%), Gaps = 28/344 (8%)
Query: 965 KEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSND-GKSKDKPPKRKKADTEGKSPS 1023
KE+ + S + SG + RSR+P+ +S+ + P + + + +SP+
Sbjct: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN 432
Query: 1024 HS---SSNRPFTPPTSTGGSKSPGSA---GRSQTPPGVATPPIPKITIQIPKGTVMVGKP 1077
+ S +R S+SP A RS++P A + + +G P
Sbjct: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP-NKARDRSRSRSPSKERDHSQLGSP 491
Query: 1078 SSHSQYTSSGSVSS--------SGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSS 1129
S + S S S S SK S S S + +S E S S
Sbjct: 492 SKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSP 551
Query: 1130 SMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSS--TKMKPQGKPSSLMNPSLS 1187
S S S + + P + SS ++ + K S P S
Sbjct: 552 SEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRAS 611
Query: 1188 KPNISPSHSRPPGG---------SDKLASPMKP-VPGTPPSSKAKSPISSGSGGSHMSGT 1237
+ S SR P S K + P + VP +P ++ + SS S S T
Sbjct: 612 SKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKT 671
Query: 1238 SSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMS 1281
SS S SG + + +++ T SSS S ++
Sbjct: 672 SSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKLA 715
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 87.0 bits (214), Expect = 1e-16
Identities = 112/457 (24%), Positives = 183/457 (40%), Gaps = 42/457 (9%)
Query: 1037 TGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSG--------- 1087
+ G+ + ++G S T GV+T I ++ G +V H+ TSSG
Sbjct: 39 SSGASTATNSGSSVTSSGVSTATISGSSVT-SNGVSIVTNSEFHT--TSSGISTATNSEF 95
Query: 1088 -SVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNS 1146
+VSS S + +S SS++SS AST+ +SS +S+ +S SS SSG+S + NS
Sbjct: 96 STVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSD--SSTTSSGASTATNS 153
Query: 1147 SQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLA 1206
S +S T S+ SS + S++ + + + N S S + G S
Sbjct: 154 DSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATN-SESSTTSSGASTATN 212
Query: 1207 SPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSC 1266
S + ++ ++ SG S + T+S S SS ++ S S T + +
Sbjct: 213 SESRTTSNGAGTATNSESSTTSSGAS--TATNSESSTPSSGAGTATNSESSTTSSGAGTA 270
Query: 1267 TASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLD 1326
T S SS SSG S ++ S G + + N + S T+ G T+
Sbjct: 271 TNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTS------SGANTATNSDSSTTS 324
Query: 1327 GQMGVSTNSSSHPMSS----KHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESK 1382
+TNS S SS N + S ++SG+S ++ ++S
Sbjct: 325 SGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVS 384
Query: 1383 NVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASS-----KNYGSPLI- 1436
+ ST + G S + ++ + G S+ SS N GS +
Sbjct: 385 SGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTS 444
Query: 1437 --SGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSI 1471
SG+ + SHS S A SE++ G S+
Sbjct: 445 AGSGTAALTGMHTTSHSASTAV------SEAKPGGSL 475
Score = 82.4 bits (202), Expect = 3e-15
Identities = 107/444 (24%), Positives = 174/444 (39%), Gaps = 34/444 (7%)
Query: 1078 SSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYS-SQG 1136
+S S T S +SS S + +S SS +SS ST+ SS + S +S ++ S G
Sbjct: 27 TSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSG 86
Query: 1137 SSGSSQSKNSSQSGG----KPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNIS 1192
S ++ S+ S+ S G S T G S+ ++S P S+ N S + +
Sbjct: 87 ISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATN---SDSSTT 143
Query: 1193 PSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMS--------GTSSSSGMK 1244
S + SD + + T S S +S + S S T+S S
Sbjct: 144 SSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTT 203
Query: 1245 SSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLT 1304
SS ++ S S+ T + + T S SS +SSG+S +++ S G + N + S T
Sbjct: 204 SSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTT 263
Query: 1305 AVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNM-----SGGEFQGKREKSD 1359
+ G T+ + + TNS S SS N S G ++
Sbjct: 264 S------SGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATN 317
Query: 1360 KDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGE 1419
D S S SG+S ++ ++S + + ST + G S + + + G S+
Sbjct: 318 SDSSTTS-SGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTAT 376
Query: 1420 GLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSP-----AYTPQNLDSE-SESGSSIAE 1473
SS + ST + ++S+S A T N +S + SG++ A
Sbjct: 377 NSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTAT 436
Query: 1474 KSYQNSPSSDDGIRPLPEYSTEKH 1497
S + S+ G L T H
Sbjct: 437 NSGSSVTSAGSGTAALTGMHTTSH 460
Score = 80.1 bits (196), Expect = 2e-14
Identities = 97/425 (22%), Positives = 167/425 (39%), Gaps = 24/425 (5%)
Query: 1080 HSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSG 1139
H + ++ + +S+ + + S SS +S+A+ SG S S G S++ +S S +S G S
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGS--SVTSSGVSTATISGSSVTSNGVSI 74
Query: 1140 SSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPP 1199
+ S+ + S G S T S+ SS + + S+ + + + N S S P
Sbjct: 75 VTNSEFHTTSS---GISTATNSEFSTVSSGISIATNSESSTTSSGASTATN---SESSTP 128
Query: 1200 GGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKT 1259
A+ + +S A + SS + + T+S S SS ++ S S
Sbjct: 129 SSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTV 188
Query: 1260 PPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGP 1319
+++ T S SS +SSG+S +++ +S G + N + S T+ G T+
Sbjct: 189 SSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTS------SGASTATN 242
Query: 1320 GGEDPLDGQMGVSTNSSSHPMSS----KHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSS 1375
G +TNS S SS N +S +SG++ ++
Sbjct: 243 SESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATN 302
Query: 1376 KKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASS-----KN 1430
++S + + +T + G S + ++ + G S+ SS N
Sbjct: 303 SESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATN 362
Query: 1431 YGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSE-SESGSSIAEKSYQNSPSSDDGIRPL 1489
GS S T S S A T +S + SG+S A S ++ SS
Sbjct: 363 SGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATN 422
Query: 1490 PEYST 1494
E ST
Sbjct: 423 SESST 427
Score = 79.3 bits (194), Expect = 3e-14
Identities = 95/402 (23%), Positives = 170/402 (42%), Gaps = 40/402 (9%)
Query: 928 TVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPG 987
T S SV ++ E H+ S G ++T + T S S+ + G
Sbjct: 59 TATISGSSVTSNGVSIVTNSEFHTTSSG--ISTATNSEFSTVSSGISIATNSESSTTSSG 116
Query: 988 LDSKPGKRSRTPSNDGKS---KDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPG 1044
+ S TPS+ + D A T S S ++S+ T S + S G
Sbjct: 117 ASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSG 176
Query: 1045 SAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSH------- 1097
++ + + + T +S S TSSG+ +++ S+S
Sbjct: 177 ASTATNSESSTVSSRASTAT-------------NSESSTTSSGASTATNSESRTTSNGAG 223
Query: 1098 ---HSHSSSSSSSASTSGKMKSSK-SEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGG-- 1151
+S SS++SS AST+ +SS S G+ ++ S S +S G+ ++ S++S+ S G
Sbjct: 224 TATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGIS 283
Query: 1152 ----KPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLAS 1207
S+P + ++ S S+ ++ + S + S + + + AS
Sbjct: 284 TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAS 343
Query: 1208 PMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSS--SGLGSSGSLSQKTPPSSNS 1265
+ SS A + +SGS + SGTS+++ +SS S S+ + S+ + SS +
Sbjct: 344 TATNSESSTTSSGASTATNSGS-STTSSGTSTATNSESSTVSSGASTATTSESSTTSSGA 402
Query: 1266 CTA--SSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTA 1305
TA S SS SSG+S +++ +S G + + N S+T+
Sbjct: 403 STATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTS 444
Score = 67.0 bits (162), Expect = 1e-10
Identities = 94/418 (22%), Positives = 163/418 (38%), Gaps = 33/418 (7%)
Query: 772 SDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSS-SSGHSQSTLFDSDVFQTNN 830
S + + + + S I+ + ST+ + T S+ SSG S +T DS +
Sbjct: 88 STATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGA 147
Query: 831 NENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSG 890
+ +D + ++A+ + +S+S T + SG ESS
Sbjct: 148 STATNSDSSTTSSEASTATNSESST------------------TSSGASTATNSESSTVS 189
Query: 891 DNDDFKGFASQALNTLGVPMLGGDNGETKFKG---NNQADTVDFSIISVAGKALAPADLM 947
AS A N+ G + T + +N A T S S + A
Sbjct: 190 SR------ASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNS 243
Query: 948 EHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKD 1007
E + S G T T + +ST+S G+ + S TPS+ +
Sbjct: 244 ESSTPSSGAGTATNS-ESSTTSSGAGTATNSESSTVSS-GISTVTNSESSTPSSGANTAT 301
Query: 1008 KPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQI 1067
+ + + SS T+T S S+G S ++ +
Sbjct: 302 NSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTAT 361
Query: 1068 PKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSK-SEGSSSSK 1126
G+ +S + + S +VSS S + S SS++SS AST+ +SS S G+S++
Sbjct: 362 NSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTAT 421
Query: 1127 LSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNP 1184
S S +S G++ ++ S +S S G G++ +T +S S+ST + + KP + P
Sbjct: 422 NSESSTTSSGANTATNSGSSVTSAGS-GTAALTGMHTTSHSASTAVS-EAKPGGSLVP 477
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 85.9 bits (211), Expect = 3e-16
Identities = 151/703 (21%), Positives = 242/703 (34%), Gaps = 100/703 (14%)
Query: 871 NSQSQSGFGEEYFDESSQSGDNDDFKGFA-SQALNTLGVPMLGGDNGETKFKGNNQADTV 929
+ Q++S GE + QS D+ G QA + + G +G ++
Sbjct: 3291 HEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEES 3350
Query: 930 DFSIISVAGKA--------LAPADLMEHHSGSQGPLL--------TTGDLGKEKTQKRVK 973
D +S G+A + D SG G L + G+ +T +
Sbjct: 3351 DTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRR 3410
Query: 974 EGN------GTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS 1027
+G+ +S + S G D+ G P + + + + D G S SH S
Sbjct: 3411 QGSHHEQARDSSRHSASQEGQDTIRGH----PGSSRRGRQGSHYEQSVDRSGHSGSHHSH 3466
Query: 1028 NRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSG 1087
+T +S S G+S + + + + G S HS ++
Sbjct: 3467 --------TTSQGRSDASRGQSGS----------RSASRQTRNDEQSGDGSRHS-WSHHH 3507
Query: 1088 SVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGS-----SGSSQ 1142
S+ S HS S S+ ++S+++GSS S+ S S S+ S S S
Sbjct: 3508 EASTQADSSRHSQSGQGQSAGP-----RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 3562
Query: 1143 SKNSSQSGGKPGSSPITKH--GLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG 1200
+ S+Q + GS T H + S + Q N S + S +R
Sbjct: 3563 HRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSA 3622
Query: 1201 GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP 1260
G G+ A S SG G S SG + SSG SQ +
Sbjct: 3623 GERH---------GSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG-------SQASD 3666
Query: 1261 PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPG 1320
+S + + S S+ G + Q+ S++G+S R SG
Sbjct: 3667 SEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGR-------------------SGRS 3707
Query: 1321 GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE 1380
G VST+ S + S G QG R + +D S+ S S D+ +
Sbjct: 3708 GSFLYQ----VSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPG 3763
Query: 1381 SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGST 1440
S+ G G G S S + T Q ++S G ++S+ + SG
Sbjct: 3764 SRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDAS-HGQSGSRSASRETRNEEQSGDG 3822
Query: 1441 PKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500
+H GS H S + S+S G S + + SS Y + ++
Sbjct: 3823 SRHS-GSRHHEAS-TQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRS 3880
Query: 1501 KKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQS 1543
+ + R++ RD R SH SP+ SD S
Sbjct: 3881 ESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSS 3923
Score = 80.5 bits (197), Expect = 1e-14
Identities = 133/601 (22%), Positives = 207/601 (34%), Gaps = 47/601 (7%)
Query: 960 TGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
+GD + + + + +S S G + G R+ S+D +R D+E
Sbjct: 1226 SGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSER 1285
Query: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
S S S ++ + S GS+ PG + G + + GT + SS
Sbjct: 1286 LSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQ------SGTHHT-ESSS 1338
Query: 1080 HSQYTSS--GSVSSSGSKSHHSHSSSSSSS-------ASTSGKMKSSKSEGSSSSKLSSS 1130
H Q SS + SS G + H S+ SS S ++ S GSS S++++S
Sbjct: 1339 HGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNS 1398
Query: 1131 MYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPN 1190
S+ S S S + Q+G S + G S SS + SS +
Sbjct: 1399 EGHSEDSDTQSVSAH-GQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQ 1457
Query: 1191 ISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLG 1250
+PS GG +S+ G GS G S +S G
Sbjct: 1458 TAPS----TGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSG 1513
Query: 1251 SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL 1310
SG T P S + S S S + ++ Q G S SR+ +PS A
Sbjct: 1514 HSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRA--GSS 1571
Query: 1311 KHGVVTSGPGGEDPLDGQMGVST----NSSSHPMSSK---HNMSGGEFQGKREKSDKDKS 1363
+H V G + G S +S H S+ + S + RE+S
Sbjct: 1572 RHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSR 1631
Query: 1364 KVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRP 1423
+ S ++ES T A+ GG + + PGE G +
Sbjct: 1632 NPRSHQEDRASHGHSAESSRQSGTRHAE----TSSGGQAASSQEQARSSPGERHGSRHQQ 1687
Query: 1424 QMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIA-------EKSY 1476
SS + G+ S+ + G+ S S A + ES++ S A ++S+
Sbjct: 1688 SADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSH 1747
Query: 1477 QNSPSSDDGIRP------LPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKP 1530
Q S G R L + ST + + + R R R + HS
Sbjct: 1748 QESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQ 1807
Query: 1531 E 1531
E
Sbjct: 1808 E 1808
Score = 76.6 bits (187), Expect = 2e-13
Identities = 142/625 (22%), Positives = 228/625 (36%), Gaps = 80/625 (12%)
Query: 963 LGKEKTQKRVKEGNGTSNSTLSGPGLDSK---PGKRSRTPSNDGK--SKDKPPKRKKADT 1017
L + K +R + +G S+S ++ ++ P + SRT G S+D+ + D+
Sbjct: 251 LEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDS 310
Query: 1018 EGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKP 1077
E S S S ++ S GS+ P S + G + + GT
Sbjct: 311 ERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQ------SGT------ 358
Query: 1078 SSHSQYTSSGSVSSSGSKSHHS----HSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYS 1133
H++ +S G +SS ++ S H S SA +S S+ G +SS +S +
Sbjct: 359 -RHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSS--RHSATGRGQASSAVSDRGH- 414
Query: 1134 SQGSSGS--SQSKNSSQSGGKPGSSPITKHGL------------------SSGSSSTKMK 1173
+GSSGS S S+ S++ S K GL SGSS ++
Sbjct: 415 -RGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVS 473
Query: 1174 PQGKPSSL-----------MNPSLSKPNISPSHSRPPGGSDKL-ASPMKPVPGTPPSSKA 1221
+P S + S HS G D + P G S
Sbjct: 474 THEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHE 533
Query: 1222 KSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSS------FSS 1275
+S SG GSH S T+S +S G S S S++T S + S SS
Sbjct: 534 QSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASS 593
Query: 1276 SGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVT---SGPGGEDPLDGQMGVS 1332
S SQ G S G SRN+ S++ D H + SG + S
Sbjct: 594 QADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS 653
Query: 1333 TNSSSHPMSSKHNMSG-GEFQGKREKSDKDKSKVSTSGSSVDSSK--KTSESKNVGSTGV 1389
+ S HP S + +G G KS ++ S+SG + S + ++S + GS
Sbjct: 654 RDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQ 713
Query: 1390 AKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKH-ERGSP 1448
+ S G+ +A ++ G G Q S+ + + S H + G
Sbjct: 714 LQSADSSRHSGTGHGQASSAVRDSGHRGSSG--SQATDSEGHSEDSDTQSVSGHGQAGHH 771
Query: 1449 SHSKSPAYTPQNLDSESESGSSIAEKS-YQNSPSS------DDGIRPLPEYSTEKHKKHK 1501
S + ++ + SGS + + S ++ S SS G+R + +
Sbjct: 772 QQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRH 831
Query: 1502 KEKKKVKDKDRDRDRDKDRDKKKSH 1526
+ +D R R ++ SH
Sbjct: 832 SASQDGQDTIRGHPGSSRRGRQGSH 856
Score = 71.2 bits (173), Expect = 7e-12
Identities = 159/748 (21%), Positives = 259/748 (34%), Gaps = 105/748 (14%)
Query: 871 NSQSQSGFGEEYFDESSQSGDNDDF----KGFASQALNTLGVPMLGGDNGETKFKGNNQA 926
+ Q++S GE + QS D+ +G AS A++ G G + +
Sbjct: 373 HEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENS 432
Query: 927 DTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGP 986
DT SV+G A H +E T+ R E +G S S+L
Sbjct: 433 DTQ-----SVSGHGKAGLRQQSH---------------QESTRGRSGERSGRSGSSLYQV 472
Query: 987 GLDSKPGK-RSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGS 1045
+P RT ++ G + ++ + D+ S S + P S+ G +
Sbjct: 473 STHEQPDSAHGRTGTSTGGRQGSHHEQAR-DSSRHSASQEGQDTIRGHPGSSRGGRQGSH 531
Query: 1046 AGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHS----HS 1101
+S G + T Q + G+ S S + + SG + HS H
Sbjct: 532 HEQSVNRSGHSGSHHSHTTSQ-GRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHE 590
Query: 1102 SSSSSSASTSGKM--------KSSKSEGSSSSKLSSSMYSSQGS-----SGSSQSKNSSQ 1148
+SS + +S ++ ++S+++GSS S+ S S S+ S S S S+Q
Sbjct: 591 ASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQ 650
Query: 1149 SGGKPGS-------SPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGG 1201
+ GS HG S+ SS + SS + S S G
Sbjct: 651 EQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGS 710
Query: 1202 SDKLASPMKPVPGTPPSSKAKSPI-------SSGSGGSHMSGTSSSSGMKSSSGLGSSGS 1254
+L S +A S + SSGS + G S S +S SG G +G
Sbjct: 711 RHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGH 770
Query: 1255 LSQKTPPS----SNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL 1310
Q S S + S SF S+ S++ HG + G S + D
Sbjct: 771 HQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWT-GPSTGVRQGSHHEQARDNS 829
Query: 1311 KHGVVTSGPGGEDPLDGQMGVS---TNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVST 1367
+H ++ G+D + G G S S H S + G + +
Sbjct: 830 RH---SASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQ 886
Query: 1368 SGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMAS 1427
SGS S+ +T+ ++ G H+ S + ++ + G+S G + S
Sbjct: 887 SGSR--SASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGS 944
Query: 1428 S---------KNYGSPLISGSTPKHERGSP------------SHSKSPAYTPQNLDSESE 1466
S + S SGS ++ RGS SH + A + DS +
Sbjct: 945 SVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQ 1004
Query: 1467 SGSSIAEKS-----------YQNSPSSDDGIRPLPEYSTEKHK--KHKKEKKKVKDKDRD 1513
SG+ AE S ++SP G R + +H ++ V+D
Sbjct: 1005 SGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHW 1064
Query: 1514 RDRDKDRDKKKSHSIKPESWSKSPISSD 1541
+ HS + ++ S S D
Sbjct: 1065 GSSGSQASDSEGHSEESDTQSVSGHGQD 1092
Score = 66.2 bits (160), Expect = 2e-10
Identities = 161/801 (20%), Positives = 263/801 (32%), Gaps = 166/801 (20%)
Query: 808 RDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNP 867
+DS S GHS+ DS+ + + + N + + + D + P S D +
Sbjct: 2893 QDSDSEGHSE----DSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR 2948
Query: 868 DL---------------LNSQSQSGFGEEYFDESSQSGDNDDFKGFA-SQALNTLGVPML 911
+ Q++S GE + QS D+ G QA + +
Sbjct: 2949 QSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR---- 3004
Query: 912 GGDNGETKFKGN----NQADTVDFSIISVAGKALAPADLMEHHSGSQGPL-LTTGDLGKE 966
D+G + G+ N+ + D SV+ A + H ++G T+G G
Sbjct: 3005 --DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSF 3062
Query: 967 KTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKP---------PKRKKADT 1017
Q E + +S+ +GP + G R + + P +
Sbjct: 3063 LYQVSTHEQSESSHGW-TGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGR 3121
Query: 1018 EG-------KSPSHSSSNRPFTPPTSTG---------GSKSPGSAGRSQTPPG------V 1055
+G S HS S+ T TS G GS+S R++ G V
Sbjct: 3122 QGYHHEHSVDSSGHSGSHHSHT--TSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSV 3179
Query: 1056 ATPPIPKITIQIPKGTVMVGKPSSHSQYT--SSGSVSSSGSKSHHSHSS---SSSSSAST 1110
+ I + + V S S+ + SVS HS S S S+S +
Sbjct: 3180 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 3239
Query: 1111 SGKMKSSKSEGS----------------SSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPG 1154
G ++ GS + S ++ SSG + + Q+ PG
Sbjct: 3240 RGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPG 3299
Query: 1155 SSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPG 1214
++H S+ SS P+G+ SS + SR G S AS + G
Sbjct: 3300 ERHGSRHQQSADSSRHSGIPRGQASSAVR-----------DSRHWGSSGSQASDSE---G 3345
Query: 1215 TPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS 1274
S +S G G H S+ +S G SGS + S +A + +
Sbjct: 3346 HSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRT 3405
Query: 1275 SSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTN 1334
S+G S Q S S S+ G+D + G
Sbjct: 3406 STGRRQGSHHEQARDSSRHSASQE----------------------GQDTIRG------- 3436
Query: 1335 SSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIII 1394
HP SS+ G ++ ++S S S + S S +S + ++ +
Sbjct: 3437 ---HPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDE 3493
Query: 1395 SKHDGGSPSIKAKVTLQKPGES-----SGEGLRPQMASSKNYGSPLI------------- 1436
DG S +S SG+G +S+N GS +
Sbjct: 3494 QSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSE 3553
Query: 1437 --SGSTPKHERGS------------PSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSS 1482
SGS ++ RGS SH + A + +S +SG+ AE S +S
Sbjct: 3554 RWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAAS 3613
Query: 1483 DDGIRPLPEYSTEKHKKHKKE 1503
+ E+H H ++
Sbjct: 3614 SH--EQARSSAGERHGSHHQQ 3632
Score = 65.5 bits (158), Expect = 4e-10
Identities = 100/493 (20%), Positives = 169/493 (34%), Gaps = 44/493 (8%)
Query: 1075 GKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS 1134
G+ S S + SG S HS S +++ S + SS +S S
Sbjct: 1209 GQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGS 1268
Query: 1135 QGSSGSSQSKNSSQSGGKPGSSPITKHGLS----------SGSSSTKMKPQGKPSSLMNP 1184
S S ++S S GS+ HG S G G +
Sbjct: 1269 SVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQ 1328
Query: 1185 SLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMK 1244
S + S SH + ++ S G+ A S SG G S SG +
Sbjct: 1329 SGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHR 1388
Query: 1245 SSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLT 1304
SSG + S + S +A + S S++ Q G S G+S S + S +
Sbjct: 1389 GSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVS-S 1447
Query: 1305 AVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSG--GEFQGKREKSDKDK 1362
+ HG GG + +++ S + + G G +G R+ S ++
Sbjct: 1448 HEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQ 1507
Query: 1363 SKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLR 1422
S + S S T + ++ S H P ++ T + E SG+G R
Sbjct: 1508 SVDRSGHSGYHHSHTTPQGRSDAS----------HGQSGPRSASRQTRNE--EQSGDGSR 1555
Query: 1423 PQMASSKNYGSPLISGSTPKHER-------GSPSHSKSPAYTPQNLDSESESGSSIAEKS 1475
S + P + +H + GS + + + Q+ DSE S S E+
Sbjct: 1556 ---HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDS--ERR 1610
Query: 1476 YQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSK 1535
+++ + G S + +H + +DR ++S + E+ S
Sbjct: 1611 SESASRNHYG-------SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSG 1663
Query: 1536 SPISSDQSLSMTS 1548
+S Q + +S
Sbjct: 1664 GQAASSQEQARSS 1676
Score = 65.1 bits (157), Expect = 5e-10
Identities = 131/610 (21%), Positives = 207/610 (33%), Gaps = 67/610 (10%)
Query: 973 KEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFT 1032
++ S + S G D+ G P + + + + D G S SH S
Sbjct: 823 EQARDNSRHSASQDGQDTIRGH----PGSSRRGRQGSHHEQSVDRSGHSGSHHSH----- 873
Query: 1033 PPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVG----KPSSH---SQYTS 1085
+T +S S G+S + T + Q G+ G + SSH S+++
Sbjct: 874 ---TTSQGRSDASRGQSGSRSASRTTRNEE---QSRDGSRHSGSRHHEASSHADISRHSQ 927
Query: 1086 SGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKL---SSSMYSSQGS----- 1137
+G S GS++ SS S + + G + S+ S+S+ S+ S GS
Sbjct: 928 AGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRS 987
Query: 1138 -----SGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNIS 1192
+G S +SS+ G P + + +S + P + S S S
Sbjct: 988 HHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHS 1047
Query: 1193 -------PSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKS 1245
S R G S G S +S G G H S+ S
Sbjct: 1048 GIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWS 1107
Query: 1246 SSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTA 1305
G SGS + S +A + +S+G S Q S S S+ + ++ A
Sbjct: 1108 GGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRA 1167
Query: 1306 VIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMS-----SKHNMSGGEFQGKREKSDK 1360
+ G G E +D + G S + SH S + H SG ++ + DK
Sbjct: 1168 HPGSRRGG--RQGSHHEQSVD-RSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDK 1224
Query: 1361 DKSKVST-SGS---SVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGES 1416
S SGS S +S VG + S+H G S S +
Sbjct: 1225 QSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSE 1284
Query: 1417 --SGEGLRPQMASSKNYGSPLISGSTPK--HERGSPSHSKSPAYTPQNLDSESESGSS-- 1470
SG R SS+ GS H+ SH S + Q+ +ES S
Sbjct: 1285 RLSGSASRNHHGSSREQSR---DGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQ 1341
Query: 1471 --IAEKSYQNSPSSDDGIRPLPEYSTEKHK--KHKKEKKKVKDKDRDRDRDKDRDKKKSH 1526
+ + ++SP G R + +H H++ V+D + H
Sbjct: 1342 AVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGH 1401
Query: 1527 SIKPESWSKS 1536
S ++ S S
Sbjct: 1402 SEDSDTQSVS 1411
Score = 64.7 bits (156), Expect = 7e-10
Identities = 139/663 (20%), Positives = 219/663 (33%), Gaps = 96/663 (14%)
Query: 952 GSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPG--------LDSKPGKR--SRTPSN 1001
GS+ P D +GT ++ S G S PG+R SR +
Sbjct: 1629 GSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQS 1688
Query: 1002 DGKSKDKPPKRKK-------ADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPG 1054
S D R++ + G S S +S + + + T + G AG Q
Sbjct: 1689 ADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQ 1748
Query: 1055 VATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKM 1114
+T + S + SGS S S S+ + ST G+
Sbjct: 1749 EST------------------RGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQ 1790
Query: 1115 KSSKSEGSSSSKLSSSMY----------SSQGSSGSSQSKNSSQSGGKPGSSPITKHGLS 1164
+S + SS+ S+S SS+G S + S S G GS H S
Sbjct: 1791 RSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSH--HSHTTS 1848
Query: 1165 SGSSSTKMKPQGKPS---SLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKA 1221
S G S N S S SR S + S G SS
Sbjct: 1849 QERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGP 1908
Query: 1222 KSPISSGSGGS-------HMSGTSSSSGMKSSSGLGSSGSLSQ--KTPPSSNSCTASSSS 1272
++ + GS S H + SG S + LGS+ S+ P S+ +
Sbjct: 1909 RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHG 1968
Query: 1273 FSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVS 1332
S+ S S +++ SS+G++ S +++ +A +HG + +G
Sbjct: 1969 HSADSSRQSGTRHTESSSRGQAASSHEQARSSA---GERHGSHHQLQSADSSRHSGIGHG 2025
Query: 1333 TNSSSHPMSSKHNMSGGEFQGKREKS-DKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAK 1391
SS+ S SG + S D D VS G + + ES G +G
Sbjct: 2026 QASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESAR-GQSG--- 2081
Query: 1392 IIISKHDGGSPSIKAKVTLQKPGESSGEGLRP-----------QMASSKNYGSPLISGST 1440
+ G S S +V+ + ES+ P Q S + + T
Sbjct: 2082 ----ESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDT 2137
Query: 1441 PKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500
+ G + ++ Q++D SGS + + Q + G
Sbjct: 2138 IRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRG-----------QSGS 2186
Query: 1501 KKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRL 1560
+ +K DK++ D + SH + SW+ S S +S S R S +
Sbjct: 2187 RSASRKTYDKEQSGDGSR---HSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSV 2243
Query: 1561 SPD 1563
S D
Sbjct: 2244 SQD 2246
Score = 62.0 bits (149), Expect = 4e-09
Identities = 140/672 (20%), Positives = 217/672 (32%), Gaps = 76/672 (11%)
Query: 871 NSQSQSGFGEEYFDESS-QSGDNDDFKGFA-SQALNTLGVPMLGGDNGETKFKGNNQADT 928
+ Q++S GE + QS D+ G QA + + G +G ++
Sbjct: 1994 HEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSED 2053
Query: 929 VDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGL 988
D +S GKA GP + KE + + E +G S S L
Sbjct: 2054 SDTQSVSAQGKA--------------GPHQQSH---KESARGQSGESSGRSGSFLYQVST 2096
Query: 989 --DSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTG--GSKSPG 1044
S+ PS G+ + + + S + R P+ G GS
Sbjct: 2097 HEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQ 2156
Query: 1045 SAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSS 1104
S RS G + T Q + G+ S S + SG S HS S
Sbjct: 2157 SVDRS----GHSGSHHSHTTSQ-GRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHH 2211
Query: 1105 SSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLS 1164
+S+ S +G SS +S S S S +S S + GS+ HG +
Sbjct: 2212 EASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSA 2271
Query: 1165 -----SGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGS-----DKLASPMKPVPG 1214
GS + + + + S+ + + GG ++ S G
Sbjct: 2272 QEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHG 2331
Query: 1215 TPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS 1274
+ A S SG G S SG + SSG SQ + +S + + S S
Sbjct: 2332 SHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG-------SQASDSEGHSEDSDTQSVS 2384
Query: 1275 SSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTN 1334
+ G + Q+ S++G+S R SG G VST+
Sbjct: 2385 AHGQAGPHQQSHQESTRGRSAGR-------------------SGRSGSFLYQ----VSTH 2421
Query: 1335 SSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIII 1394
S + S G QG K +D S+ STS D+ S + G G +
Sbjct: 2422 EQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQL 2481
Query: 1395 SKHDGGSPSIKAKVTLQ-----KPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPS 1449
G S S + T Q G S Q + + G + HE S +
Sbjct: 2482 VDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRA 2541
Query: 1450 HSKSPAYTPQNLDSESESGSSIAEKSYQNSPS---SDDGIRPLPEYSTEKHKKHKKEKKK 1506
S + Q + + Q+S S S+D R S H +++ +
Sbjct: 2542 DSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRD 2601
Query: 1507 VKDKDRDRDRDK 1518
R D+
Sbjct: 2602 GSRHPRSHQEDR 2613
Score = 59.3 bits (142), Expect = 3e-08
Identities = 156/772 (20%), Positives = 273/772 (35%), Gaps = 103/772 (13%)
Query: 784 SDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIA 843
S + + S+ P TS + + + +DS S GHS+ DS+ + + + N + + +
Sbjct: 2547 SQVGQGQSEGPRTSRNWGSSFS--QDSDSQGHSE----DSERWSGSASRNHHGSAQEQLR 2600
Query: 844 DAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQAL 903
D + P S + + ++G G D S QSG QA
Sbjct: 2601 DGSRHPRS-------------------HQEDRAGHGHSA-DSSRQSGTRHTQTSSGGQAA 2640
Query: 904 NTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDL 963
++ GE G++ + D S S G H + + +G
Sbjct: 2641 SSH--EQARSSAGERH--GSHHQQSADSSRHSGIG-----------HGQASSAVRDSGHR 2685
Query: 964 GKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPS 1023
G +Q EG+ + T S S G+ + +S + + + +T G S S
Sbjct: 2686 GYSGSQASDNEGHSEDSDTQSV----SAHGQAG----SHQQSHQESARGRSGETSGHSGS 2737
Query: 1024 HSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQY 1083
S+ G P + GR + A Q + T+ G P
Sbjct: 2738 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIR-GHP------ 2790
Query: 1084 TSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQS 1143
GS HH HS SS + + +S+ +S S S +S+ + QS
Sbjct: 2791 ---GSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS 2847
Query: 1144 KNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQG-KPSSLMNPSLSKPNISPSHS----RP 1198
+ S+ G T +S S + + + +G + S S+S+ + S HS R
Sbjct: 2848 GDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERW 2907
Query: 1199 PGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMK----SSSGLGSSG- 1253
G + + S +S +G H + +S SG + SS G +S
Sbjct: 2908 SGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSH 2967
Query: 1254 ----SLSQKTPPSSNSCTASSSSFSSSGSSMSSS---QNQHGSSKGKSPSRNKKPSLTAV 1306
S + + S + +A SS S G +SS + H G S N+ S +
Sbjct: 2968 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD 3027
Query: 1307 IDKLK-HGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKV 1365
+ HG +G + + G S +S H S + +S E + +S +
Sbjct: 3028 TQSVSAHG--QAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHE----QSESSHGWTGP 3081
Query: 1366 STSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQM 1425
ST G ++ +S ++ + I H G S + + +SSG
Sbjct: 3082 STRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGH------ 3135
Query: 1426 ASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDG 1485
S ++ S S RG S S+S + T +N + +S + ++ S +D
Sbjct: 3136 --SGSHHSHTTSQGRSDASRGQ-SGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHAD-- 3190
Query: 1486 IRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDK-KKSHSIKPESWSKS 1536
+H + + + + + R + +D + HS E WS S
Sbjct: 3191 --------ISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGS 3234
Score = 58.5 bits (140), Expect = 5e-08
Identities = 93/478 (19%), Positives = 166/478 (34%), Gaps = 28/478 (5%)
Query: 1082 QYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSS 1141
++ SG +++ + ++ ++ S +S S+G SSS+++ S + +
Sbjct: 226 KWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQ 285
Query: 1142 QSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGG 1201
+S+ + G S +++ S G S + G S + S + + S
Sbjct: 286 ESRTRKRRG-----SRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHD 340
Query: 1202 SDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPP 1261
D+ + ++ S G S SS G + SG S S+ +
Sbjct: 341 EDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSAT 400
Query: 1262 SSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGG 1321
+++ S GSS S + + G S+ S +++ A + + H T G G
Sbjct: 401 GRGQASSAVSDRGHRGSSGSQASDSEGHSE-NSDTQSVSGHGKAGLRQQSHQESTRGRSG 459
Query: 1322 EDPLDGQMG-----VSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSK 1376
E G+ G VST+ + S G QG + +D S+ S S D+ +
Sbjct: 460 E--RSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIR 517
Query: 1377 KTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQ-----KPGESSGEGLRPQMASSKNY 1431
S G G G S S + T Q G+S Q + +
Sbjct: 518 GHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQS 577
Query: 1432 GSPLISGSTPKHERGSPSHSKSPAYTPQNLDS----ESESGSSIAEKSYQNSPSSDDGIR 1487
G + HE S + S + Q S GSS+++ S S D
Sbjct: 578 GDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDS--- 634
Query: 1488 PLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLS 1545
+S + H ++ + +D R + + H +S KS Q+ S
Sbjct: 635 --ERWSGSASRNHHGSAQE-QSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSS 689
Score = 42.7 bits (99), Expect = 0.003
Identities = 47/194 (24%), Positives = 71/194 (36%), Gaps = 16/194 (8%)
Query: 960 TGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
+GD + + + +S S G G R S+D + D+E
Sbjct: 3819 SGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSER 3878
Query: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
+S S S ++ + S GS+ PGS+ R T V + P+ + K
Sbjct: 3879 RSESASRNHHGSSREQSRDGSRHPGSSHR-DTASHVQSSPV--------QSDSSTAKEHG 3929
Query: 1080 HSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS----Q 1135
H S S SG +S S SSSS + G + + +G S Y S
Sbjct: 3930 HFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEG---TERQKGQSGLVWRHGSYGSADYDY 3986
Query: 1136 GSSGSSQSKNSSQS 1149
G SG S++ S S
Sbjct: 3987 GESGFRHSQHGSVS 4000
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 85.1 bits (209), Expect = 5e-16
Identities = 220/1020 (21%), Positives = 362/1020 (35%), Gaps = 114/1020 (11%)
Query: 542 PASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQN 601
P S+ G++ + + PT+T TT ++ H G E + + N
Sbjct: 601 PGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTET-TLLPDN 659
Query: 602 PILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMA--GNTKNHPMLMNLLKDNPAQDFST 659
+ LL+ + + SS PH T P S G + + PA +T
Sbjct: 660 TTASGLLEAS----MPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTT 715
Query: 660 LYGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDS 719
S+ +E +S GSP ++ + + +S L E + + + + + D+
Sbjct: 716 ---SAFVEPSTTSHGSPSS--IPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT 770
Query: 720 QNPIFDVNMTADTLDTPHITPAPSQCST---PPTTYPQPVPHPQPSIQRMVRL-SSSDSI 775
+ + + T+ + T I+ APS S PT+Y H P SS +
Sbjct: 771 TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY-----HSSPGSTATTHFPDSSTTS 825
Query: 776 GPDVTDILSDIAEEASK---LPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNE 832
G I S +++A+ LP+ S + +G SSG ++T +E
Sbjct: 826 GRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 885
Query: 833 NPYT------DPADLIADAAGSPS--SDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFD 884
T PA ++ A+ + S S+ T G +S + G
Sbjct: 886 RSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 945
Query: 885 ESSQSGDNDDFKGFASQALNTLGVPMLGGDN----------GETKFKGNNQADTVDFSII 934
S G D AS +G P + G T G ++ T +S
Sbjct: 946 SHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSP 1005
Query: 935 SVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGT-------SNSTLSGPG 987
L+PA + TT T G+ T S ++ S PG
Sbjct: 1006 RSPDTTLSPASTTSSGVSEES---TTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPG 1062
Query: 988 -LDSKPGKRSRTPSNDGKSKDK------------PPKRKKAD--TEGKSPSHSSSNRPFT 1032
D+ RS T S+ G P A E +P HSS+ P T
Sbjct: 1063 STDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRT 1122
Query: 1033 PPTSTGGSKSPGSAGRSQT-PPGVATPPIPKITIQ--IPKGTVMVGKPSS--HSQYTSSG 1087
+ G + G + Q+ P T P P T + T G PSS + +++S
Sbjct: 1123 TLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASS 1182
Query: 1088 SVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSS 1147
+ +S HSS + + + S ++S S + S++ +SS GS+ + SS
Sbjct: 1183 TTFGRSEESTTVHSSPVAPATTPS----PARSTTSGLVEESTAYHSSPGSTQTMHFPESS 1238
Query: 1148 QSGGKPGSSPI----TKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSD 1203
+ G+ S T H +SS S+T + S +P P S G S+
Sbjct: 1239 TASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSE 1298
Query: 1204 KL----ASP----MKPVPG--TPPSSKAKSP---ISSGSGGSHMSGTSSSSGMKSSSGLG 1250
+ +SP + P+P T A+S IS GS + ++ T+++ G+ + S +
Sbjct: 1299 ESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTIL 1358
Query: 1251 SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL 1310
S S S P AS +S S SG S + P+ L+
Sbjct: 1359 YSSSRS----PDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQ----- 1409
Query: 1311 KHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDK--DKSKVSTS 1368
+ S PG + ++T+S + ++ H+ G S S+ ST+
Sbjct: 1410 ESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTT 1469
Query: 1369 GSSVDSSKKT---SESKNVGSTGVAKIIISKHDGGSPSI-KAKVTLQKPGESSGEGLRPQ 1424
S S +T S S + G + ++ A +T G+ E
Sbjct: 1470 FYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQ---ESTAFH 1526
Query: 1425 MASSKNYGSPLISGSTPKHERGSPSH---SKSPAYTPQNLDSESESGSSIAEKSYQNSPS 1481
+S +PL + ST G P+ S SP YT S S SG + ++ SPS
Sbjct: 1527 SSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPS 1586
Score = 80.5 bits (197), Expect = 1e-14
Identities = 233/1037 (22%), Positives = 364/1037 (35%), Gaps = 187/1037 (18%)
Query: 537 KKNLPPASSPGYGMTTGNNPMSGTT------TPTNTFPGGPITTLFNMSMSIKDRHESVG 590
+++ P SSP TT S T+ T + PG T F S + E
Sbjct: 392 EESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESA 451
Query: 591 --HGEDFSKVSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVS-----SMAGNTKNHP 643
HG S P T+ L T S++GS+ T +S S A ++
Sbjct: 452 TFHGSTTHTKSSTPSTTAALAHTSYH-SSLGSTETTHFRDSSTISGRSEESKASHSSPDA 510
Query: 644 MLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQ 703
M +L PA GS+P S+ SP I SGS +T S P +
Sbjct: 511 MATTVL---PA-------GSTPSVLVGDSTPSP---ISSGSMETTALPGSTTKPGLSEKS 557
Query: 704 TEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSI 763
T +S +MT+ + T ST T +P P S
Sbjct: 558 TT------FYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQ 611
Query: 764 QRMVRLSS--------------SDSIGPDVTDILSDIAE-EASKLP--STSDDCPAIGTP 806
+ SS + S+GP+ T S E + LP +T+ P
Sbjct: 612 ESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMP 671
Query: 807 LRDSSSSGHS------------QSTLFDSDVFQTNNNENPYTDPADLIADAA---GSPSS 851
+ S+ S H+ +ST F S + P T + + + GSPSS
Sbjct: 672 VHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSS 731
Query: 852 DSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPML 911
PT H + + SG EE S G T+ P
Sbjct: 732 -IPTTH-----------ISARSTTSGLVEESTTYHSSPGSTQ-----------TMHFPES 768
Query: 912 GGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKR 971
+G + + + T H+ S P TT L +E T
Sbjct: 769 DTTSGRGEESTTSHSSTT--------------------HTISSAPS-TTSALVEEPTSYH 807
Query: 972 VKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPF 1031
G S +T P + + G+S++ D G + S
Sbjct: 808 SSPG---STATTHFPD----------SSTTSGRSEESIASHSSQDATGTIVLPARSTNSV 854
Query: 1032 TPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSS 1091
ST S GS + P TP + + + T P S + S S +S
Sbjct: 855 LLGESTTSPISSGSMETTALPGSTTTPGLSE------RSTTFHSSPRSPATTLSPASTTS 908
Query: 1092 SGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSG- 1150
SG + S S S T+ S+ + G S + S++ +SS GS+ ++ S+ +
Sbjct: 909 SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS--RHSTTSHSSPGSTDTTLLPASTTTXL 966
Query: 1151 -GKPGSSPI--------------TKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISP-- 1193
G+P +SPI T GLS S++ P+ ++L S + +S
Sbjct: 967 VGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1026
Query: 1194 --SHSRPPGGSDKLASP-MKPVPGTPPSSKAK--SPISSGSGGSHMSGTSSSSGMKSSSG 1248
SHSRP G + A P +PG S A SP S+ + S S T+SS G +S++
Sbjct: 1027 TTSHSRP-GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTF 1085
Query: 1249 LGSSGSLSQKTPPSSNSCT----ASSSSFSSSGSSMSSSQNQHGSSK-GKSPSRNKKPSL 1303
GS P + + + AS+ SS+GS ++ +++ G+S + PS
Sbjct: 1086 HSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSS 1145
Query: 1304 TAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMS--SKHNMSGGEFQGKREKSDKD 1361
+ P + +ST S P S + H + G+ E+S
Sbjct: 1146 KDTM-----------PAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEES--- 1191
Query: 1362 KSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGL 1421
+T SS + T ++G+ + + H SP + T+ P S+ G
Sbjct: 1192 ----TTVHSSPVAPATTPSPARSTTSGLVEESTAYHS--SPG--STQTMHFPESSTASGR 1243
Query: 1422 RPQMASSKNYGSPLISG---STPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQN 1478
+ +S + + IS +T S+ SP ES + S +E+S +
Sbjct: 1244 SEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTAS 1303
Query: 1479 SPSSD-DGIRPLPEYST 1494
S D +GI PLP + T
Sbjct: 1304 HSSPDTNGITPLPAHFT 1320
Score = 58.5 bits (140), Expect = 5e-08
Identities = 127/615 (20%), Positives = 222/615 (36%), Gaps = 85/615 (13%)
Query: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
+SP + + T++G S+ + S T +TP + + ++
Sbjct: 427 RSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETT 486
Query: 1080 HSQYTSSGSVSSSGSKSHHSHSSS------------------SSSSASTSGKMKSSKSEG 1121
H + +S+ S S SK+ HS + S+ S +SG M+++ G
Sbjct: 487 HFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPG 546
Query: 1122 SSS----SKLSSSMYSSQGS----------SGSSQSKNSSQSGGKPGSS-------PITK 1160
S++ S+ S++ YSS S + S S+ S+ S +PGS+ T
Sbjct: 547 STTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 606
Query: 1161 HGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPS----HSRPPGGSDKLASPMKPVPGTP 1216
GLS S+++ P ++L S + ++ P HSRP L G
Sbjct: 607 PGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGL- 665
Query: 1217 PSSKAKSPISSGSGGSHM----SGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSC-----T 1267
+A P+ S + H +G+++ G ++ S + ++ PP++ S T
Sbjct: 666 --LEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPST 723
Query: 1268 ASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDG 1327
S S SS ++ S+++ +S + + P T + TSG G E
Sbjct: 724 TSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM-HFPESDTTSGRGEEST--- 779
Query: 1328 QMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKV--------STSGSSVDSSKKTS 1379
S +S++H +SS + + + S +TSG S +S S
Sbjct: 780 ---TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHS 836
Query: 1380 ESKNVG-----STGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMA-------S 1427
G + +++ + S + T PG ++ GL + S
Sbjct: 837 SQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRS 896
Query: 1428 SKNYGSPLISGSTPKHERGSPSHSK-SPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGI 1486
SP + S+ E + SHS+ +T DS + G S + +SP S D
Sbjct: 897 PATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD-- 954
Query: 1487 RPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSM 1546
L ST + + + S K ++ SP S D +LS
Sbjct: 955 TTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1014
Query: 1547 TSNTILSADRPSRLS 1561
S T S S
Sbjct: 1015 ASTTSSGVSEESTTS 1029
Score = 55.5 bits (132), Expect = 4e-07
Identities = 168/765 (21%), Positives = 276/765 (36%), Gaps = 94/765 (12%)
Query: 774 SIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGH--SQSTLFDSDVFQTNNN 831
S PDV+++ + EE ST I ++S G+ S ST SD F T
Sbjct: 56 SSSPDVSELTATKHEETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTT--- 112
Query: 832 ENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGD 891
++D + GS + T HF + ++ S SG G
Sbjct: 113 ---FSDYGVSVTFITGSTA----TKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSA 165
Query: 892 NDDFKG------FASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPA- 944
F G S ++ T +P G T G ++ T +S + L+PA
Sbjct: 166 TSVFVGEPKTSPITSASMETTALP------GSTTTAGLSEKSTTFYSSPRSPDRTLSPAR 219
Query: 945 ----DLMEHHSGSQ---GPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSR 997
+ E + S GP T T V + + S+S PG +
Sbjct: 220 TTSSGVSEKSTTSHSRPGPTHTIA-FPDSTTMPGVSQESTASHSIPGSTDTTLSPG--TT 276
Query: 998 TPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVAT 1057
TPS+ G ++ T SP ++ + R T++G ++ S P
Sbjct: 277 TPSSLGP---------ESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTL 327
Query: 1058 PPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSS-----SASTSG 1112
P T + T S + SG+ S+ S HSS SS+ SAS++
Sbjct: 328 SPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTT 387
Query: 1113 KMKSSKSEGSSSSKLSSSMYSSQGSSGSS----------QSKNSSQSGGKPGSSPITKHG 1162
S +S SS ++++ S +S +S S+Q+ P SS + H
Sbjct: 388 LGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHS 447
Query: 1163 LSS-----GSSSTKMKPQGKPSSLMNPSL--SKPNISPSHSRPPGGSDKLASPMKPVPGT 1215
S ++ TK ++L + S S + +H R + K +
Sbjct: 448 EESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESK-ASHS 506
Query: 1216 PPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPP--SSNSCTASSSSF 1273
P + A + + +GS S + G S+ S + SS + ++ T P S S T SS
Sbjct: 507 SPDAMATTVLPAGSTPSVLVGDSTPSPI-SSGSMETTALPGSTTKPGLSEKSTTFYSSPR 565
Query: 1274 SSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVST 1333
S + + +S G S+ +S + + +P T T+ G + G ST
Sbjct: 566 SPDTTHLPASMTSSGVSE-ESTTSHSRPGSTH----------TTAFPGSTTMPGLSQEST 614
Query: 1334 NSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKII 1393
S S P + +S G + + +T S S++ T N ++G+ +
Sbjct: 615 ASHSSPGPTDTTLSPGS-----TTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEAS 669
Query: 1394 ISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMAS--SKNYGSPLISGSTPKHERGSPSHS 1451
+ H S + TL G ++ +G S S N P +T S +
Sbjct: 670 MPVH---SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSH 726
Query: 1452 KSPAYTPQNLDSESESGSSIAEKS--YQNSPSSDDGIRPLPEYST 1494
SP+ P S + S + E+S Y +SP S + PE T
Sbjct: 727 GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMH-FPESDT 770
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 84.3 bits (207), Expect = 8e-16
Identities = 130/536 (24%), Positives = 200/536 (37%), Gaps = 71/536 (13%)
Query: 994 KRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS--NRPFTPPTSTGGSKSPG--SAGRS 1049
+R++ D + +D+ ++++ +GK S +R PP + P A
Sbjct: 456 ERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEW 515
Query: 1050 QTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAS 1109
+ P + P K+ + + PS + + + S+S S S S S SSS S S
Sbjct: 516 KDPWRRSKSPKKKLGVSV--------SPSRARRRRKTSASSASASNSSRSSSRSSSYSGS 567
Query: 1110 TSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSS 1169
S + +S S SS S SS S GS S+S +SS S P SP S
Sbjct: 568 GSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPS-PTPSP------HRPSIR 620
Query: 1170 TKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKP-----------VPGTPPS 1218
TK +P P S+ KP P+ + + + P KP TPP
Sbjct: 621 TKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPR 680
Query: 1219 SKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPS----SNSCTASSSSFS 1274
+ S SGSG S+ SG+SS S S S + S S + + + S A +S
Sbjct: 681 RRTLSGSGSGSGSSY-SGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPV 739
Query: 1275 SSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTN 1334
SS SS S + Q KGKS + +K K T P P G
Sbjct: 740 SSASSRSPAPAQTRKEKGKSKKEDGVKE-----EKRKRDSSTQPPKSAKPPAG-----GK 789
Query: 1335 SSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIII 1394
SS P + + G QG + K + + S K+ S
Sbjct: 790 SSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDK----------- 838
Query: 1395 SKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHS-KS 1453
D SP ++P S G R + + + GSP P+ +RG S + +
Sbjct: 839 ---DRQSPP-----PAKRPNTSPDRGSRDRKSGGR-LGSP-----KPERQRGQNSKAPAA 884
Query: 1454 PAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKD 1509
PA + L +S+S S + + S + + + ++ K+ K V+D
Sbjct: 885 PADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVED 940
Score = 66.2 bits (160), Expect = 2e-10
Identities = 93/398 (23%), Positives = 137/398 (34%), Gaps = 53/398 (13%)
Query: 965 KEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSH 1024
+ KT + +S S+ RSR+ S+ S R + + +S S
Sbjct: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
Query: 1025 SSSNRPFTPPTSTGGSKSPGSAGRSQTPPG------VATPPIPKITIQIPKGTVMVGKPS 1078
S S+ P PT + S + G PPG V P P Q K T V +P+
Sbjct: 601 SFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPT 660
Query: 1079 SHSQYTSS-------------GSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSS 1125
+ ++S SGS S S+S SSS S S S SS S +SSS
Sbjct: 661 KPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSS 720
Query: 1126 KLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKH-GLSSGSSSTKMKPQGKPSSLMNP 1184
+ S+ S+ S SS S P + K G S K + + + SS P
Sbjct: 721 SSAHSV-DSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPP 779
Query: 1185 SLSKPNISPSHSRPPGGSDKLASPMKPVPGT------------------------PPSSK 1220
+KP S+ P + + A P +P GT PS K
Sbjct: 780 KSAKPPAGGKSSQQP-STPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDK 838
Query: 1221 -------AKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSF 1273
AK P +S GS + G S + P + S
Sbjct: 839 DRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKS 898
Query: 1274 SSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLK 1311
SS +S+ + G++ KS + ++ +LK
Sbjct: 899 SSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLK 936
Score = 43.1 bits (100), Expect = 0.002
Identities = 86/367 (23%), Positives = 131/367 (35%), Gaps = 55/367 (14%)
Query: 1171 KMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPIS-SGS 1229
K K + KP S PS + + G K A K S K K +S S S
Sbjct: 478 KEKGKPKPRSPQPPS-RQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPS 536
Query: 1230 GGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGS 1289
TS+SS S+S SS S S SS S + SSS SS SS SS +
Sbjct: 537 RARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSY--SSYSSRSSRHSSFSG 594
Query: 1290 SKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGG 1349
S+ +S S + PS + + + T G P G+ G
Sbjct: 595 SRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPP--GKAG------------------- 633
Query: 1350 EFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVT 1409
EKS K + + ++ E G A+ + + + + + T
Sbjct: 634 ------EKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREAR----RKERPARTPPRRRT 683
Query: 1410 LQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGS 1469
L G SG + S++ +S + S + S S A++ + D ++ S
Sbjct: 684 LSGSGSGSGSSYSGSSSRSRSLSVSSVSSVS------SATSSSSSAHSVDSEDMYADLAS 737
Query: 1470 SIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIK 1529
++ S ++ P P + K+ K KK+ K+ R RD K S K
Sbjct: 738 PVSSASSRS---------PAP---AQTRKEKGKSKKEDGVKEEKRKRDSSTQPPK--SAK 783
Query: 1530 PESWSKS 1536
P + KS
Sbjct: 784 PPAGGKS 790
Score = 38.5 bits (88), Expect = 0.052
Identities = 56/244 (22%), Positives = 92/244 (37%), Gaps = 26/244 (10%)
Query: 887 SQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADL 946
S SG + G +S++ +L V + + T ++ A +VD S A + +
Sbjct: 687 SGSGSGSSYSGSSSRS-RSLSVSSVSSVSSATS--SSSSAHSVD----SEDMYADLASPV 739
Query: 947 MEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKP--GKRSRTPSNDGK 1004
S S P T + GK K + VKE +S+ P P GK S+ PS +
Sbjct: 740 SSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQ 799
Query: 1005 SKDKPPKR---------------KKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRS 1049
+ P++ K AD + S +PP + + SP R
Sbjct: 800 APPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRD 859
Query: 1050 QTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAS 1109
+ G P P+ Q + + P+ + S S SSS S +S ++++
Sbjct: 860 RKSGGRLGSPKPE--RQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAAST 917
Query: 1110 TSGK 1113
SGK
Sbjct: 918 KSGK 921
Score = 35.4 bits (80), Expect = 0.44
Identities = 15/47 (31%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 1491 EYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSP 1537
E+ E+ K+ +K+++ +D+DR+++R+K++ K K S +P S P
Sbjct: 452 EWERERAKRDEKDRQH-RDRDREKEREKEKGKPKPRSPQPPSRQAEP 497
Score = 33.5 bits (75), Expect = 1.7
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 11/57 (19%)
Query: 1491 EYSTEKHKKHKKE-------KKKVKDKD-RDRDRDKDRDKKKSHSIKPESWSKSPIS 1539
E+ +K ++ +KE K+ KD+ RDRDR+K+R+K+K KP+ S P S
Sbjct: 439 EHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKG---KPKPRSPQPPS 492
Score = 31.2 bits (69), Expect = 8.3
Identities = 13/78 (16%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 1476 YQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDR-----------DKKK 1524
Y+N P Y + ++ ++ +++ ++++R+RDR+++R ++ K
Sbjct: 385 YENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDK 444
Query: 1525 SHSIKPESWSKSPISSDQ 1542
+ E W + D+
Sbjct: 445 ERQRRKEEWERERAKRDE 462
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 80.9 bits (198), Expect = 9e-15
Identities = 154/682 (22%), Positives = 249/682 (36%), Gaps = 125/682 (18%)
Query: 915 NGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKE 974
N K G Q D S++ + L A + E + GP+ K+K E
Sbjct: 32 NKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKA---KKKASSSDSE 88
Query: 975 GNGTSNSTLSGPGLDSK----------PGKRSRTPSNDGKSK------DKPPKRKKADTE 1018
+ + GP PGK + S S+ D+ ++K+ +
Sbjct: 89 DSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQK 148
Query: 1019 GKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQI----PKGTVMV 1074
G P ++ PP S S + PP P I +T++ P
Sbjct: 149 GVKPQAKAAK---APPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARA 205
Query: 1075 GKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSS-----------------ASTSGKMKSS 1117
++ + SS S SSS S S S ++++ A+T+ KSS
Sbjct: 206 APKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSS 265
Query: 1118 KSEGSSSS---------KLSSSMYSS-------------------------QGSSGSSQS 1143
SE SSS K YSS Q S S
Sbjct: 266 SSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDS 325
Query: 1144 KNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRP--PGG 1201
+ S S + P TK + S +T P K ++ + S + S P P G
Sbjct: 326 SDESDSSSEEEKKPPTK---AVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAG 382
Query: 1202 SDKLASPMKPV----PGTPPSSKAKSPISSGSG-GSHMSGTSSSSGMKSSSGLGSSGSLS 1256
+ K +S V P P++ K P+ G + + +SSS SSS + +
Sbjct: 383 TTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMV 442
Query: 1257 QKTPPSSNSCTASS--SSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGV 1314
T P + + A S + + GS SSS + SS+ +K S +AV K K
Sbjct: 443 ATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSE----EEEEKTSKSAV--KKKPQK 496
Query: 1315 VTSGPGGEDPLDGQMG--VSTNSSSHPMSSKHN----MSGGEFQGKREKSDKDKSKVSTS 1368
V G P + G S+NSSS SS+ G + + K++ + + +
Sbjct: 497 VAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQN 556
Query: 1369 GSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASS 1428
G + +S++ E K A +++SK S S+K + K E++ E PQ
Sbjct: 557 GKAAKNSEEEEEEKK-----KAAVVVSK----SGSLKKR----KQNEAAKEAETPQAKKI 603
Query: 1429 KNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSY--QNSPSSDDGI 1486
K + PK ++G + SP + + E E S +A+ S+ + + D G
Sbjct: 604 KLQ----TPNTFPKRKKGE-KRASSPFRRVR--EEEIEVDSRVADNSFDAKRGAAGDWGE 656
Query: 1487 R--PLPEYSTEKHKKHKKEKKK 1506
R + +++ K +H+K KKK
Sbjct: 657 RANQVLKFTKGKSFRHEKTKKK 678
Score = 54.3 bits (129), Expect = 9e-07
Identities = 98/474 (20%), Positives = 161/474 (33%), Gaps = 73/474 (15%)
Query: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSK--LSSSMYSSQGSSGSSQ 1142
++G V+ K S S SS + +K + + L +++ S SS
Sbjct: 70 ANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSS 129
Query: 1143 SKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGS 1202
++S + + G+ + + K P+ SS + S + P + +P
Sbjct: 130 EESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITP 189
Query: 1203 DKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP-- 1260
+ + K P ++A I++G S S +SSSS S ++ + + P
Sbjct: 190 VTVKAQTK---APPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKK 246
Query: 1261 ------PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGV 1314
P + T + S SS SS + Q K P +NK ++V
Sbjct: 247 QVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQ------KKPMKNKPGPYSSV-------- 292
Query: 1315 VTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDS 1374
P P +G +K+ + + V +S S D
Sbjct: 293 ---PPPSAPPPKKSLGTQPP---------------------KKAVEKQQPVESSEDSSDE 328
Query: 1375 SKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSP 1434
S +SE + T K ++SK P K K ESS + SS++ +P
Sbjct: 329 SDSSSEEEKKPPT---KAVVSKATTKPPPAK------KAAESSSDS--SDSDSSEDDEAP 377
Query: 1435 LISGSTPKHERGSPS-HSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYS 1493
T K+ P+ +KSPA P + G +S SS++ E
Sbjct: 378 SKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEK 437
Query: 1494 TEKHKKHKKEKKKVK---------DKDRDRDRDKDRDKKKSHSIKPESWSKSPI 1538
T+K K K K RD D D S + E SKS +
Sbjct: 438 TKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEE-EEEKTSKSAV 490
Score = 50.8 bits (120), Expect = 1e-05
Identities = 78/365 (21%), Positives = 126/365 (34%), Gaps = 46/365 (12%)
Query: 1216 PPSSKAKSP---ISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSS 1272
PP+ KA P + G + + SSS +SS QK P + +
Sbjct: 100 PPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSD---DDDEEDQKKQPVQKGVKPQAKA 156
Query: 1273 FSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVS 1332
+ SS + SS P +N+KP +T V K + + S
Sbjct: 157 AKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAAS 216
Query: 1333 TNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKI 1392
++SSS SS D ++ K + + KKT K V VAK
Sbjct: 217 SSSSSSSSSSS--------------DDSEEEKAAAT------PKKTVPKKQV----VAKA 252
Query: 1393 IISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGS-PLISGSTPKHERGSPSHS 1451
+ +P+ K+ + + E +P Y S P S PK G+
Sbjct: 253 PVKA--ATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPK 310
Query: 1452 KS-----PAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLP-----EYSTEKHKKHK 1501
K+ P + ++ ES+S S +K + S +P P E S++
Sbjct: 311 KAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDS 370
Query: 1502 KEKKKVKDKDRDRDRD---KDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPS 1558
E + K ++ K KS ++KP + K P+ Q L S++ S
Sbjct: 371 SEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES 430
Query: 1559 RLSPD 1563
S +
Sbjct: 431 SSSEE 435
Score = 46.6 bits (109), Expect = 2e-04
Identities = 107/537 (19%), Positives = 176/537 (32%), Gaps = 78/537 (14%)
Query: 691 KSSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPPT 750
K+++ PP+K K D + S D +N P ITP + T
Sbjct: 155 KAAKAPPKKAKSSDSDS---DSSSEDEPPKN------------QKPKITPVTVKAQT--- 196
Query: 751 TYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCP--------- 801
+ P P + ++ ++ S + SD +EE + P
Sbjct: 197 ---KAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAP 253
Query: 802 --AIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFF 859
A TP R SSSS S S + N PY+ + PS+ P
Sbjct: 254 VKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYS--------SVPPPSAPPPKKSL- 304
Query: 860 HDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDND---DFKGFASQALNTLGVPMLGGDNG 916
G + Q E+ DES S + + K S+A T P
Sbjct: 305 --GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKA--TTKPP------- 353
Query: 917 ETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGN 976
K + +D+ D PA ++ S P +TT VK
Sbjct: 354 PAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNK--PAVTT-------KSPAVKPAA 404
Query: 977 GTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPF-TPPT 1035
G L ++ S + S+++ K+ A T+ K+ + ++ + P P
Sbjct: 405 APKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ 464
Query: 1036 STGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSK 1095
+ S S + S+ + K Q G KP+S + + S SSS
Sbjct: 465 GSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDD 524
Query: 1096 SHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGS 1155
S S S + ++ K+ G+S+ + + + K ++ K GS
Sbjct: 525 S--SEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGS 582
Query: 1156 SPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPV 1212
K ++ + T PQ K L PN P + G + +SP + V
Sbjct: 583 LKKRKQNEAAKEAET---PQAKKIKLQT-----PNTFPKRKK---GEKRASSPFRRV 628
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 77.0 bits (188), Expect = 1e-13
Identities = 128/503 (25%), Positives = 195/503 (38%), Gaps = 54/503 (10%)
Query: 1076 KPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQ 1135
+ SS S + SS S K S + SS + S S S GSS S+ +S SS
Sbjct: 486 RSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASK--SSS 543
Query: 1136 GSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSL-------MNPSLSK 1188
S S+S++SS+SG + +S + S S + +K + +++ + P +++
Sbjct: 544 HSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAE 603
Query: 1189 --PNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKS----PISSGSGGSHMSGTSSSSG 1242
P I S S PP P KP KAK+ PI S +++ T SSS
Sbjct: 604 NIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSS 663
Query: 1243 M--------KSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSS---GSSMSSSQNQHGSSK 1291
S S ++ P S S ++ S S+S S S++SS ++ S
Sbjct: 664 YHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPS 723
Query: 1292 GKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEF 1351
+S SRNK + + ++S G + NS SH KH+ S +
Sbjct: 724 SRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSH---KKHSSSSEKT 780
Query: 1352 QGKREKSDKDKS----KVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAK 1407
+ +D+S K S S SS+D S SE +V +T A+ K G
Sbjct: 781 LHSKYVKGRDRSSCVRKYSESRSSLDYS-SDSEQSSVQATQSAQ---EKEKQGQMERTHN 836
Query: 1408 VTLQKPGESSGEGLRPQMASSK-----NYGSPLISGSTPKHERGSPSHSKSPAYTPQNLD 1462
+ GE + R S K N L +GS PK + Y D
Sbjct: 837 KQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKN----------YAGSKWD 886
Query: 1463 SESESGSSIAEKSYQNS-PSSD-DGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDR 1520
SES S + + S +S PSSD + + +E + H K K K D +
Sbjct: 887 SESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNG 946
Query: 1521 DKKKSHSIKPESWSKSPISSDQS 1543
K S S S+ S+ ++
Sbjct: 947 AWKSSKQRTSTSDSEGSCSNSEN 969
Score = 52.4 bits (124), Expect = 3e-06
Identities = 104/427 (24%), Positives = 145/427 (33%), Gaps = 49/427 (11%)
Query: 1095 KSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPG 1154
K HS S SSS++S+S SE SS S+L + + K S + +
Sbjct: 191 KPTHSEGSDSSSNSSSS-------SESSSESELEHERSRRRKHKRRPKVKRSKKRRKEAS 243
Query: 1155 SS--PITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPV 1212
SS P KH ++ S + K S + KP + P P + L PV
Sbjct: 244 SSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPV 303
Query: 1213 PGTPPSSKAK--SPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASS 1270
P K +PI S S KS + G++ TPP S SC+ S
Sbjct: 304 VTAEPEPKIPDVAPIVS---------DQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESD 354
Query: 1271 SSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMG 1330
SS + Q + P +K S DKL S E L +
Sbjct: 355 DDDSSETPPHWKEEMQR--LRAYRPPSGEKWSKG---DKLSD--PCSSRWDERSLSQRSR 407
Query: 1331 VSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVA 1390
+ + + S SG + ++EK K K K KK + T
Sbjct: 408 SWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKK----------GKKQKHCRRHKQTKKR 457
Query: 1391 KIIISKHDGGSPS----IKAKVTLQKPGESSG-----EGLRPQMASSKNYGSPLISGSTP 1441
+I+I S S +K+ ++ SS R S K+ S L S
Sbjct: 458 RILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRD 517
Query: 1442 KHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHK 1501
+ S S S S + S+S S S KS +S S G R S K
Sbjct: 518 SYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKS---GHRKRASKSPRKTASQL 574
Query: 1502 KEKKKVK 1508
E K VK
Sbjct: 575 SENKPVK 581
Score = 52.0 bits (123), Expect = 5e-06
Identities = 87/375 (23%), Positives = 132/375 (35%), Gaps = 57/375 (15%)
Query: 960 TGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
TG +++ E + ++ S S +S P RSR+ S+ + R +
Sbjct: 658 TGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRS------SRSRSYSRSYTRSRS 711
Query: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
+ SHS S P + S RS + +++ G+ +
Sbjct: 712 LASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDD---------------GRRAK 756
Query: 1080 HSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSG 1139
+ SSG +S K H S S + S G+ +SS S S+ SS YSS
Sbjct: 757 R-RLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESR-SSLDYSSDSEQS 814
Query: 1140 SSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPP 1199
S Q+ S+Q K G T + K K + + +L K N+
Sbjct: 815 SVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTL-KENL-------- 865
Query: 1200 GGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQ-- 1257
SD L + KP SK S +S + S S G +S S S+
Sbjct: 866 --SDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVS 923
Query: 1258 ----KTPPSSNSCTASS--------------SSFSSSGSSMSSSQNQHG---SSKGKSPS 1296
K P++ S T +S +S S S S S+S+N G K S
Sbjct: 924 EIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKE 983
Query: 1297 RNKKPSLTAVIDKLK 1311
K+ V +KLK
Sbjct: 984 NLKREHTKKVKEKLK 998
Score = 38.9 bits (89), Expect = 0.040
Identities = 72/348 (20%), Positives = 121/348 (34%), Gaps = 11/348 (3%)
Query: 824 DVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYF 883
DV QT++N T A SP + D D N L + E
Sbjct: 1121 DVLQTDDNMEICTPDRSSPAKV----EETSPLGNARLDTPDINIVLKQDMATEHPQAEVV 1176
Query: 884 DESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAP 943
+ S ++ Q ++ + G G+ + +Q + +D + G
Sbjct: 1177 KQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLA 1236
Query: 944 ADLMEHHSGSQGPLLTT-GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSND 1002
A S + +LTT ++ + + +K N +L K + +R P N
Sbjct: 1237 APNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEV--RKTARLNRRPRNQ 1294
Query: 1003 GKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPG-SAGRSQTPPGVATPPIP 1061
S D+ + D++ +SPS S S + S ++S S RS++ ++
Sbjct: 1295 ESSSDEQTPSRDDDSQSRSPSRSRSK---SETKSRHRTRSVSYSHSRSRSRSSTSSYRSR 1351
Query: 1062 KITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEG 1121
+ +G G+ S S S + S+S SS S S S S S
Sbjct: 1352 SYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRS 1411
Query: 1122 SSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSS 1169
S S+ S +G S + +S++ G S H S SS
Sbjct: 1412 RSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESS 1459
Score = 35.4 bits (80), Expect = 0.44
Identities = 25/120 (20%), Positives = 51/120 (42%), Gaps = 19/120 (15%)
Query: 1444 ERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKE 1503
+R P+HS+ S+S S+ + S +S S E+ + +KHK+
Sbjct: 188 KRKKPTHSEG-----------SDSSSNSSSSSESSSESE-------LEHERSRRRKHKRR 229
Query: 1504 KKKVKDKDRDRDRDKDRDKKKSHSIKPESWS-KSPISSDQSLSMTSNTILSADRPSRLSP 1562
K + K R ++ + + H++ P+ S +S + +S+ ++ RP + P
Sbjct: 230 PKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPP 289
Score = 34.3 bits (77), Expect = 0.98
Identities = 73/331 (22%), Positives = 123/331 (37%), Gaps = 56/331 (16%)
Query: 1257 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVT 1316
++ P+ + + SSS+ SSS S S S+ +H S+ + R +P + + K
Sbjct: 188 KRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKR--RPKVKRSKKRRKEA--- 242
Query: 1317 SGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSD-KDKSKVSTSGSSVDSS 1375
SSS +KH M+ +G E+SD +K V +S
Sbjct: 243 ------------------SSSEEPRNKHAMNP---KGHSERSDTNEKRSVDSSAKREKPV 281
Query: 1376 KKTSESKNVGSTGVA-----KIIISKHDGGSPSIKAKVTLQKPGES-SGEGLR------- 1422
+ E V ++ ++ + P + V+ QKP S SG ++
Sbjct: 282 VRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRY 341
Query: 1423 --PQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESES-------GSSIAE 1473
P + S + S TP H + + AY P + + S+ S E
Sbjct: 342 HTPPRSRSCSESDDDDSSETPPHWKEEMQRLR--AYRPPSGEKWSKGDKLSDPCSSRWDE 399
Query: 1474 KSYQNSPSSDDGIRPLPEYSTEKHKKHKK---EKKKVKDKDRDRDRDKDRDKKKSHSIKP 1530
+S S + ST +H H K ++KKVK K + + + R K++ K
Sbjct: 400 RSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTK--KR 457
Query: 1531 ESWSKSPISSDQSLSMTSNTILSADRPSRLS 1561
S I S +S + + +R SR S
Sbjct: 458 RILIPSDIESSKSSTRRMKSSCDRERSSRSS 488
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 76.3 bits (186), Expect = 2e-13
Identities = 121/458 (26%), Positives = 160/458 (34%), Gaps = 76/458 (16%)
Query: 1075 GKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS 1134
G+ S Q+ SGS SSG H S S SS +SG +SS G S+ +S
Sbjct: 588 GQSSGFGQH-GSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSS-GYGQHGSRQTSGF--G 643
Query: 1135 QGSSGSSQSKNSSQSGGKPG-SSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISP 1193
Q SGSSQS Q G G SS +H SG SS + + + + S +
Sbjct: 644 QHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSG---HSSYGQHGFGS 700
Query: 1194 SHSRPPG------------GSDKLASPMKPVPGTPPSSKAKS----PISSGSG-----GS 1232
S S G G +L+S G S +S SGSG G
Sbjct: 701 SQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQ 760
Query: 1233 H--MSGTSS----SSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS--SSGSSMSSSQ 1284
H SG SS SSG SSG G GS S ++ S+ F SGS S+
Sbjct: 761 HESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGF 820
Query: 1285 NQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSS-- 1342
QHGS G+S + S + +HG +S G G ++ H SS
Sbjct: 821 GQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQ 880
Query: 1343 ------------------KHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNV 1384
+H G++ G + + +S S+ G S ++S
Sbjct: 881 YSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQ--HESRSHQSSYGQHGSGSSQSSGYGQH 938
Query: 1385 GSTGVAKIIISKHDGGS--------------PSIKAKVTLQKPGESSGEGLRPQMASSKN 1430
GS+ +H GS S G+SSG G +S N
Sbjct: 939 GSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSN 998
Query: 1431 YGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESG 1468
YG GS G H S T S SG
Sbjct: 999 YGQ---HGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSG 1033
Score = 75.9 bits (185), Expect = 3e-13
Identities = 153/642 (23%), Positives = 232/642 (36%), Gaps = 90/642 (14%)
Query: 872 SQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDF 931
S+ SGFG+ S +G F + S + + G G +G++ G +++ +
Sbjct: 788 SRQTSGFGQHGSGSSQSTG----FGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQS 843
Query: 932 SIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSK 991
S G + + H S G T G+ ++ G G S G G S
Sbjct: 844 SY-GQHGSGSSQSSGYGQHGSSSGQ---TSGFGQHRSSSGQYSGFGQHGS---GSGQSSG 896
Query: 992 PGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGG---------SKS 1042
G+ T S + R + G+ S SS + + S+ G S S
Sbjct: 897 FGQHG-TGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGS 955
Query: 1043 PGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSS 1102
S+G Q G G+ S Q+ SGS SSG H S SS
Sbjct: 956 GQSSGFGQHGSGS-------------------GQSSGFGQH-ESGSGKSSGFGQHESRSS 995
Query: 1103 SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHG 1162
S+ SG +SS SS ++ + SS S G SS +HG
Sbjct: 996 QSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHG 1055
Query: 1163 LSSGSSS--TKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSK 1220
SG SS + + + + SS S + S + + S + + + PG+ SS
Sbjct: 1056 TGSGQSSGFGQYESRSRQSSYGQHG-SGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSS- 1113
Query: 1221 AKSPISSGSG-----GSHMSGTSSSSGM--------KSSSGLGSSGSLSQKTPPSSNSCT 1267
SGSG G H SGT SSG +SS G +GS S +
Sbjct: 1114 GFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGS 1173
Query: 1268 ASSSSFSS--SGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPL 1325
++SF SGS SS QH S G+S G SG G L
Sbjct: 1174 GPTTSFGQHVSGSDNFSSSGQHISDSGQSTG---------------FGQYGSGSGQSTGL 1218
Query: 1326 DGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVG 1385
GQ S + + + G+ S + + + +GS V +++S+S+N
Sbjct: 1219 -GQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSD 1277
Query: 1386 STGVAKII--ISKH---DGGSPSIKAKVTL-QKPGESSGEGLRPQMASSKNYGSPLISGS 1439
S +K+ S+H GS K+ T+ ++ G + G Q + +G SG
Sbjct: 1278 SEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHG-----QRGDTTRHGH---SGH 1329
Query: 1440 TPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPS 1481
+ GS + + DSE SG S S + + S
Sbjct: 1330 GQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHS 1371
Score = 69.3 bits (168), Expect = 3e-11
Identities = 109/426 (25%), Positives = 141/426 (33%), Gaps = 65/426 (15%)
Query: 1075 GKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS 1134
G+ S Q SGS SSG H S S SS S G S+ S Y
Sbjct: 487 GQSSGFGQ-CGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQ 545
Query: 1135 QGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPS 1194
GS GSSQS Q G + +S +HGL SG S T G S + +
Sbjct: 546 HGS-GSSQSSGYGQYGSRE-TSGFGQHGLGSGQS-TGFGQYGSGSG-------QSSGFGQ 595
Query: 1195 HSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGS 1254
H G S G S +S S GS S G + +SG G GS
Sbjct: 596 HGSGSGQSSGF--------GQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGS 647
Query: 1255 LSQKTPPSSNSCTASSSSFSS--SGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKH 1312
S + S+ F SGS SS QH S G+S + S + +H
Sbjct: 648 GSSQ-----------STGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQH 696
Query: 1313 GVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGE---------------------- 1350
G +S G G ++ H +SS + S G+
Sbjct: 697 GFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSS 756
Query: 1351 -FQGKREKSDKDKSKVSTSGSSVDS------SKKTSESKNVGSTGVAKIIISKHDGGS-P 1402
F +S + +SGSS S S++TS GS ++ GS
Sbjct: 757 GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQ 816
Query: 1403 SIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLD 1462
S G+SSG G + +YG GS G H S T
Sbjct: 817 SAGFGQHGSGSGQSSGFGQHESRSHQSSYGQ---HGSGSSQSSGYGQHGSSSGQTSGFGQ 873
Query: 1463 SESESG 1468
S SG
Sbjct: 874 HRSSSG 879
Score = 67.4 bits (163), Expect = 1e-10
Identities = 164/680 (24%), Positives = 220/680 (32%), Gaps = 121/680 (17%)
Query: 875 QSGFGEEYFDESSQSG----DNDDFKGFASQALNT---LGVPMLGGDNGETKFKGNNQAD 927
QS +G+ S SG + + GF L + G G +G++ G + +
Sbjct: 540 QSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSG 599
Query: 928 TVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTL---- 983
+ S + +H SGS G G +T + G+G+S ST
Sbjct: 600 SGQSSGFGQHESRSGQSSYGQHSSGSSQSS-GYGQHGSRQTSGFGQHGSGSSQSTGFGQY 658
Query: 984 -SGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKS 1042
SG G S G+ S G+S E +S S F S+G +
Sbjct: 659 GSGSGQSSGFGQHV---SGSGQSSGF------GQHESRSGHSSYGQHGFGSSQSSGYGQH 709
Query: 1043 PGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTS------------SGSVS 1090
S+G+ T + + G+ SS Q+ S SGS
Sbjct: 710 GSSSGQ---------------TSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQ 754
Query: 1091 SSGSKSHHSHSSSSSSSASTSGKMKSS----------KSEGSSSSKLSSSMYSSQGSSGS 1140
SSG H S S SS +SG +SS G S S S Q SGS
Sbjct: 755 SSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGS 814
Query: 1141 SQSKNSSQSGGKPG--------------------------SSPITKHGLSSGSSSTKMKP 1174
QS Q G G SS +HG SSG +S
Sbjct: 815 GQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSG--FG 872
Query: 1175 QGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHM 1234
Q + SS + H G S GT S S SH
Sbjct: 873 QHRSSSGQYSGFGQ------HGSGSGQSSGFGQ-----HGT--GSGQYSGFGQHESRSHQ 919
Query: 1235 SGTSS-SSGMKSSSGLGSSGSLSQKT----PPSSNSCTASSSSFSSSGSSMSSSQNQHGS 1289
S SG SSG G GS S +T S S +S SGS SS QH S
Sbjct: 920 SSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHES 979
Query: 1290 SKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGG 1349
GKS + S ++ + +HG +S G G +T H SS G
Sbjct: 980 GSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFG 1039
Query: 1350 EFQGKREKSDKDKSKVSTSGSSVDSSKKTSESK--NVGSTGVAKIIISKHDGGSPSIKAK 1407
+ ++S + SG S + S S+ + G G G S S
Sbjct: 1040 QHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHG---------SGSSQSSGYG 1090
Query: 1408 VTLQKPGESSGEGL-RPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESE 1466
G++SG G RP S +G GS G H + E
Sbjct: 1091 QHGSNSGQTSGFGQHRPGSGQSSGFGQ---YGSGSGQSSGFGQHGSGTGKSSGFAQHEYR 1147
Query: 1467 SG-SSIAEKSYQNSPSSDDG 1485
SG SS + +S SS G
Sbjct: 1148 SGQSSYGQHGTGSSQSSGCG 1167
Score = 66.6 bits (161), Expect = 2e-10
Identities = 123/551 (22%), Positives = 192/551 (34%), Gaps = 80/551 (14%)
Query: 964 GKEKTQKRVKEGNGTSNSTLSGPGLDSKPGK-RSRTPSNDGKSKDKPPKRKKADTEGKSP 1022
G T +R + +S+S + G + G S+ S G+S+ KR + T G++
Sbjct: 1869 GSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQT-THGQTG 1927
Query: 1023 SHSSSNRPFTPPTSTGGSKSPGSAGR-------SQTPPGVATPPIPKITIQIPKGTVMVG 1075
+ P T GS++ G G S+ P GV+ Q G
Sbjct: 1928 DTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESG 1987
Query: 1076 KPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQ 1135
T+ G + + H H S+ + T+G+ S SE S S S S
Sbjct: 1988 SSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSG---VSH 2044
Query: 1136 GSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSS--STKMKPQGKPSSLMNPSLSKPNISP 1193
SG + + SQ G+ GSS +HG + G + +T+ G S S +
Sbjct: 2045 THSGHAHGQAGSQH-GESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGS 2103
Query: 1194 SHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGT---------------S 1238
HS ++ S + +A+S G GS + G
Sbjct: 2104 GHSE--SSDSEVHSGVSHTHSGHTYGQARS--QHGESGSAIHGRQGTIHGQTGDTTRHGQ 2159
Query: 1239 SSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRN 1298
S G + +G ++G SS+S S +S + SG + S + ++HG S
Sbjct: 2160 SGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSG------- 2212
Query: 1299 KKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREK- 1357
+SG G + GQ G T +H + G G+R
Sbjct: 2213 -----------------SSGHGRQGTTHGQTG-DTTRHAHYGYGQSTQRGSRTTGRRGSG 2254
Query: 1358 -SDKDKSKVSTSGSSVDS----SKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQK 1412
S+ S+V + GS S + S+ + GST ++ + G +
Sbjct: 2255 HSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHG------ 2308
Query: 1413 PGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLD----SESESG 1468
SG G Q S + S S S+ + GS K +Y P D SG
Sbjct: 2309 ---HSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYGPSG 2365
Query: 1469 SSIAEKSYQNS 1479
S KS NS
Sbjct: 2366 GS--RKSISNS 2374
Score = 63.5 bits (153), Expect = 2e-09
Identities = 131/535 (24%), Positives = 178/535 (33%), Gaps = 56/535 (10%)
Query: 950 HSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKP 1009
H G L T+G TQ R++E S+ SG G DS G+RS S
Sbjct: 237 HGGLSCGLETSGH-ESNSTQSRIREQK--LGSSCSGSG-DS--GRRSHACGYSNSSGCGR 290
Query: 1010 PKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAG--RSQTPPGVATP---PIPKIT 1064
P+ + + + + G K G P G P P +
Sbjct: 291 PQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSY 350
Query: 1065 IQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSS 1124
Q G G+P + +GS SS + S S S S+ S SSS
Sbjct: 351 SQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSS 410
Query: 1125 SKLSSSMYSSQGSSGSSQSKNSSQSG-GKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMN 1183
++ S Q SGSSQS + Q G G SS +H SG + G+ S +
Sbjct: 411 NEFSKC---DQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTC------GQHESTSS 461
Query: 1184 PSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSS-SSG 1242
SL G D+ S S K GSG SG SG
Sbjct: 462 QSL--------------GYDQHGS---------SSGKTSGFGQHGSGSGQSSGFGQCGSG 498
Query: 1243 MKSSSGLGSSGSLSQKTP--PSSNSCTASSSSFSSSGS-SMSSSQNQHGSSKGKSPSRNK 1299
SSG G GS+S ++ S + SS F S S SS QHGS +S +
Sbjct: 499 SGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQ 558
Query: 1300 KPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQ---GKRE 1356
S +HG+ + G G S+ H S + G+ + G+
Sbjct: 559 YGS-RETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSS 617
Query: 1357 KSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGS-PSIKAKVTLQKPGE 1415
+SG S++TS GS ++ GS S + G+
Sbjct: 618 YGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQ 677
Query: 1416 SSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSS 1470
SSG G + +YG G G H S T E SG S
Sbjct: 678 SSGFGQHESRSGHSSYGQ---HGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQS 729
Score = 63.2 bits (152), Expect = 2e-09
Identities = 97/449 (21%), Positives = 167/449 (37%), Gaps = 81/449 (18%)
Query: 1084 TSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSS----- 1138
T+ G + + SH H S+ + T+G+ +SS SE S S S ++ G +
Sbjct: 1619 TTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAG 1678
Query: 1139 ---GSSQSKNSSQSGGKPGSSPIT------KHGLSSGSSSTKMKPQGKPSSLMNPSLSKP 1189
G S+S + G G + T HGL++ + S +G S + S
Sbjct: 1679 SQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYS 1738
Query: 1190 NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGL 1249
+S +HS G + +++S + G H G + + + SG
Sbjct: 1739 GVSHTHSGHTHGQAR-----------SQHGESESIVHERHGTIH--GQTGDTTRHAHSGH 1785
Query: 1250 GSSGSLSQKTP------PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSL 1303
G S +T S S + S FS S + Q GS G+S S
Sbjct: 1786 GQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESES------- 1838
Query: 1304 TAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKS 1363
++D+ +HG T G G+ Q G ++ S ++ SG S+ S
Sbjct: 1839 --IVDE-RHG-TTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSG--------HSESSDS 1886
Query: 1364 KVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRP 1423
+V + GS S S++++ G ++ + K + + T + G+++ G
Sbjct: 1887 EVHSGGSHTHSGHTHSQARS--QHGESESTVHK--------RHQTTHGQTGDTTEHG--- 1933
Query: 1424 QMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSD 1483
++G + +GS RGS HS + DSE SG S + + +
Sbjct: 1934 ----HPSHGQTIQTGSRTTGRRGS-GHS-------EYSDSEGPSGVSHTHSGHTHGQAGS 1981
Query: 1484 DGIRPLPEYSTEKHKKHKKEKKKVKDKDR 1512
PE + H++H + D R
Sbjct: 1982 H----YPESGSSVHERHGTTHGQTADTTR 2006
Score = 58.9 bits (141), Expect = 4e-08
Identities = 119/590 (20%), Positives = 204/590 (34%), Gaps = 88/590 (14%)
Query: 965 KEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSH 1024
+E+T + +G S ST+ ++ G+ + + +R T + H
Sbjct: 1366 QEQTHSQAGSQHGESESTVHERH-ETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGH 1424
Query: 1025 SSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYT 1084
S S+ +GGS P S ++ G + G+ + G+ T
Sbjct: 1425 SESS---DSEVHSGGSHRPQSQEQTHGQAG---------SQHGESGSTVHGRHG-----T 1467
Query: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYS----SQGSSGS 1140
+ G + +H+ H S+ +ST+G+ S SE S S S ++ + G SGS
Sbjct: 1468 THGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGS 1527
Query: 1141 SQSKNSS-------QSGGKPGSSPITKHGLSSGSSSTK--MKPQGKPSSLMNPSLSKPNI 1191
++ S + G+ G + T+H S +T+ + G+ + + S
Sbjct: 1528 QHGESESIIHDRHRITHGQTGDT--TRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVH 1585
Query: 1192 SPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGS 1251
S RP + + + G G + S G + G +
Sbjct: 1586 SGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRT 1645
Query: 1252 SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSR----NKKPSLTAVI 1307
+G SS+S S S + +G + + +QHG S+ P R + + T
Sbjct: 1646 TGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRH 1705
Query: 1308 DKLKHGVVT-----------SGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSG-------- 1348
HG+ T SG +G GVS S H + G
Sbjct: 1706 AHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHE 1765
Query: 1349 --GEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVG------STGVAKIIISKHDGG 1400
G G + D + S G S + +T+ ++ G S G + H G
Sbjct: 1766 RHGTIHG--QTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRG 1823
Query: 1401 SPSIKA--------KVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSK 1452
+A + ++ G + G+ S +G SGS+ R S HS+
Sbjct: 1824 HTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRS-GHSE 1882
Query: 1453 SPAYTPQNLDSESESGSSIAEKSYQNSPS-SDDGIRPLPEYSTEKHKKHK 1501
S DSE SG S + +S + S G E + HK+H+
Sbjct: 1883 SS-------DSEVHSGGSHTHSGHTHSQARSQHG-----ESESTVHKRHQ 1920
Score = 55.5 bits (132), Expect = 4e-07
Identities = 123/549 (22%), Positives = 194/549 (35%), Gaps = 81/549 (14%)
Query: 978 TSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTST 1037
T+ SG G ++ G R+ + G S+ +D+EG S
Sbjct: 1777 TTRHAHSGHGQSTQTGSRTTGRRSSGHSE-------YSDSEGHS---------------- 1813
Query: 1038 GGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTV--MVGKPSSHSQYTSSGSVSSSGS- 1094
G S+ P S G + G I + GT G S HSQ + G + SGS
Sbjct: 1814 GFSQRPHSRGHTHGQAGSQHGESESI-VDERHGTTHGQTGDTSGHSQ-SGHGQSTQSGSS 1871
Query: 1095 ---KSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGG 1151
+ HS SS S + G + S S S G S S+ K + G
Sbjct: 1872 TTGRRRSGHSESSDSEVHSGG-------SHTHSGHTHSQARSQHGESESTVHKRHQTTHG 1924
Query: 1152 KPGSSPITKHG-------LSSGSSSTKMKPQG--KPSSLMNPS-LSKPNISPSHSRPPGG 1201
+ G + T+HG + +GS +T + G + S PS +S + +H +
Sbjct: 1925 QTGDT--TEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSH 1982
Query: 1202 SDKLASPMKPVPGTPPSSKAKSPISSGSG-GSHMSGTSSSSGMKSSSGLGSSGSLSQKTP 1260
+ S + GT A + SG G S ++G ++S S S
Sbjct: 1983 YPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGV 2042
Query: 1261 PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKS--PSRNKKPSLTAVIDKLKHGVVTSG 1318
++S A + S G S SS +HG++ G++ +R+ + G
Sbjct: 2043 SHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRG 2102
Query: 1319 PGGEDPLDGQM--GVSTNSSSHPMS---SKHNMSGGEFQGKR-----EKSDKDKSKVSTS 1368
G + D ++ GVS S H S+H SG G++ + D + S
Sbjct: 2103 SGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGH 2162
Query: 1369 GSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQ---KPGESSGEGLRPQ- 1424
G S + +T+ + + + + H SP+ Q + G+S G Q
Sbjct: 2163 GQSTQTGSRTTGRQRSSHSESSDSEV--HSEASPTHSGHTHSQAGSRHGQSGSSGHGRQG 2220
Query: 1425 ----------MASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEK 1474
+ YG GS RGS HS+S + S + SG +
Sbjct: 2221 TTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGS-GHSESSDSEVHSWGSHTHSGHIQGQA 2279
Query: 1475 -SYQNSPSS 1482
S Q P S
Sbjct: 2280 GSQQRQPGS 2288
Score = 53.9 bits (128), Expect = 1e-06
Identities = 82/408 (20%), Positives = 143/408 (35%), Gaps = 57/408 (13%)
Query: 1075 GKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS 1134
G Q T+ G + H H S+ + + TSG+ + S S+ + S ++S
Sbjct: 1304 GSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSE-----VHSG 1358
Query: 1135 QGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPS 1194
SQ + SQ+G + G S T H + + G S
Sbjct: 1359 VSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHS-------------G 1405
Query: 1195 HSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGS 1254
H G S + S G+ S + S + SGGSH + + ++ S G SGS
Sbjct: 1406 H----GQSTQRGSRTTGRRGSGHSESSDSEVH--SGGSHRPQSQEQTHGQAGSQHGESGS 1459
Query: 1255 LSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS--KGKSPSRNKKPSLTAVIDKLKH 1312
++ +G + + HG S +G S + + + D H
Sbjct: 1460 TVH---------GRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVH 1510
Query: 1313 GVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSV 1372
+ G GQ G S + +H ++ G+ S + + +GS
Sbjct: 1511 SGGSHTHSGH--THGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRT 1568
Query: 1373 DSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYG 1432
++TS S++ S H GGS ++ G++ + P+ + +G
Sbjct: 1569 TGRQRTSHSESTDS--------EVHSGGSHRPHSRE--HTYGQAGSQHEEPEFTVHERHG 1618
Query: 1433 SP----------LISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSS 1470
+ SG +RGS + + + ++ DSE SG S
Sbjct: 1619 TTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVS 1666
Score = 52.0 bits (123), Expect = 5e-06
Identities = 78/343 (22%), Positives = 119/343 (34%), Gaps = 24/343 (6%)
Query: 1078 SSHSQY-TSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQG 1136
S H ++ T+ G + +H H S+ + T+G+ S SE S S S ++ G
Sbjct: 2064 SVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSG 2123
Query: 1137 SSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHS 1196
+ +SG T HG + +T+ G S S + SHS
Sbjct: 2124 HTYGQARSQHGESGSAIHGRQGTIHGQT--GDTTRHGQSGHGQSTQTGSRTTGRQRSSHS 2181
Query: 1197 RPPGGSDKLASPMKPVPGTPPSSKAKSPI-SSGSGGSHMSGTSSSSGMKSSSGLGSSGSL 1255
++ S P S+A S SGS G GT + G + +
Sbjct: 2182 E--SSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGT--THGQTGDTTRHAHYGY 2237
Query: 1256 SQKTPPSSNSCTASSSSFSSSGSSMSSSQNQH---GSSKGKSPSRNKKPSLTAVIDKLKH 1312
Q T S + S S S S S H G +G++ S+ ++P T H
Sbjct: 2238 GQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTV------H 2291
Query: 1313 G--VVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQG-KREKSDKDKSKVSTSG 1369
G T G G+ G G ++ + SS+ FQ E+ S+V G
Sbjct: 2292 GRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSR----ASHFQSHSSERQRHGSSQVWKHG 2347
Query: 1370 SSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQK 1412
S + + S G K I + H S A L +
Sbjct: 2348 SYGPAEYDYGHTGYGPSGGSRKSISNSHLSWSTDSTANKQLSR 2390
Score = 45.8 bits (107), Expect = 3e-04
Identities = 64/270 (23%), Positives = 100/270 (37%), Gaps = 29/270 (10%)
Query: 1082 QYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSS 1141
Q T G + H S+ + + T+G+ +SS SE S S S + + G + S
Sbjct: 2144 QGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQ 2203
Query: 1142 QSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG- 1200
QSG T HG + +T+ G S S + HS
Sbjct: 2204 AGSRHGQSGSSGHGRQGTTHGQT--GDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDS 2261
Query: 1201 -----GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSL 1255
GS + ++ G S+ + P S+ G + T +G + G G
Sbjct: 2262 EVHSWGSHTHSGHIQGQAG----SQQRQPGSTVHG--RLETTHGQTGDTTRHGHSGYGQS 2315
Query: 1256 SQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSK-GKSPSRNKKPSLTAVIDKLKHGV 1314
+Q T S SS +S S SS + +HGSS+ K S A D G
Sbjct: 2316 TQ---------TGSRSSRASHFQSHSSERQRHGSSQVWKHGSYG-----PAEYDYGHTGY 2361
Query: 1315 VTSGPGGEDPLDGQMGVSTNSSSHPMSSKH 1344
SG + + + ST+S+++ S+H
Sbjct: 2362 GPSGGSRKSISNSHLSWSTDSTANKQLSRH 2391
Score = 37.4 bits (85), Expect = 0.12
Identities = 68/267 (25%), Positives = 98/267 (36%), Gaps = 55/267 (20%)
Query: 1069 KGTVMVGKPSSHSQYTSSGSVSSSGSK--SHHSHSSSSSSSASTSGKMKSSKSEGSSSSK 1126
+GTV S+ + G++SSSG++ S + SS + + GK + GSSS +
Sbjct: 148 RGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDR----HGSSSVE 203
Query: 1127 LSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSL 1186
L + S S S +S +SG SGS+S + K G S + S
Sbjct: 204 LRERINKSH-ISPSRESGEEYESG--------------SGSNSWERKGHGGLSCGLETSG 248
Query: 1187 SKPNISPSHSRPP------GGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSG---- 1236
+ N + S R GS + S + +S S SH G
Sbjct: 249 HESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGN 308
Query: 1237 ------TSSSSGMKSSSGLG--SSGSLSQKTPPSSNSCTASSSSFS-------------- 1274
+ SG+K G G S G S P SN C+ S S
Sbjct: 309 QFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGG 368
Query: 1275 --SSGSSMSSSQNQHGSSKGKSPSRNK 1299
+GSS SS Q+GS +S S +
Sbjct: 369 QWRTGSSQSSCCGQYGSGGSQSCSNGQ 395
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 76.3 bits (186), Expect = 2e-13
Identities = 96/402 (23%), Positives = 142/402 (35%), Gaps = 102/402 (25%)
Query: 975 GNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPP 1034
G G ++ G G G+RSR+ S + + P ++ + + +
Sbjct: 197 GAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQK----- 251
Query: 1035 TSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGS 1094
R ++PP + TPP+ +P T+ SS+ S
Sbjct: 252 ----------HKKRPESPPSILTPPV------VP---------------TADKVSSSASS 280
Query: 1095 KSHHSHSS--SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGK 1152
SHH S+ +S SS + GK SS S KLSS S +S SS S +SS S G
Sbjct: 281 SSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGG 340
Query: 1153 PGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPV 1212
P ++ Q P P L +P DK + P P
Sbjct: 341 PFQPAVS-------------SLQSSPDFSAFPKLEQPE-----------EDKYSKPTAPA 376
Query: 1213 PGTPPSSKAKSP----------ISSGSGG-SHMSGTSSSSG---------MKSSSGLGSS 1252
P PPS A P + SG G S T+SSSG KS GS
Sbjct: 377 PSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSG 436
Query: 1253 GSL-SQKTPPSSNSCTASSSSFSSSG----SSMSSSQNQHGSSKGKSPSRNKKPSLTAVI 1307
S + K P+ ++ + +G +S +++HG + K SRNK+
Sbjct: 437 ASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKG-SRNKEG------ 489
Query: 1308 DKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGG 1349
T GP Q+ T +++ P S +S G
Sbjct: 490 --------TGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSG 523
Score = 53.5 bits (127), Expect = 2e-06
Identities = 52/184 (28%), Positives = 71/184 (38%), Gaps = 9/184 (4%)
Query: 1125 SKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNP 1184
SK+ +S +SS G G + S GG G + +S S+ + P
Sbjct: 182 SKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKS 241
Query: 1185 SLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMK 1244
K + H + P + +P P P + K S SS S + +S S +
Sbjct: 242 RKDKERLKQKHKKRPESPPSILTP----PVVPTADKVSSSASSSSHHEASTQETSESSRE 297
Query: 1245 SSSGLGSSGSLSQKTPPSSN----SCTASSSSFSSSGSSMSSSQNQHG-SSKGKSPSRNK 1299
S SS SLS K S+ S S+SS SSS SS S Q SS SP +
Sbjct: 298 SKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSA 357
Query: 1300 KPSL 1303
P L
Sbjct: 358 FPKL 361
Score = 49.3 bits (116), Expect = 3e-05
Identities = 93/391 (23%), Positives = 139/391 (35%), Gaps = 78/391 (19%)
Query: 933 IISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLS----GPGL 988
++ A K + A HH S ++T + +E G +S+ S G L
Sbjct: 267 VVPTADKVSSSASSSSHHEAST-----------QETSESSRESKGKKSSSHSLSHKGKKL 315
Query: 989 DSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAG- 1047
S G S T ++ S S SSS PF P S+ S SA
Sbjct: 316 SSGKGVSSFTSASSSSSS----------------SSSSSGGPFQPAVSSLQSSPDFSAFP 359
Query: 1048 ----------RSQTPPGVATPPIPKITIQIPKGTVM--------VGKPSSHSQYTSSGSV 1089
T P + PP P + PK + G S TSS
Sbjct: 360 KLEQPEEDKYSKPTAPAPSAPPSPSAP-EPPKADLFEQKVVFSGFGPIMRFSTTTSSSGR 418
Query: 1090 SSSGSKSHHS--HSSSSSSSASTSGKMKS----------SKSEGSSSSKLSSSMYSSQGS 1137
+ + S + H + S +SA T +M + + G K +S S G
Sbjct: 419 ARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGP 478
Query: 1138 SGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNP--SLSKPNISPSH 1195
S+N +GG ++P +G ++T P S + + LS PS
Sbjct: 479 GRPKGSRNKEGTGGP--AAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSG 536
Query: 1196 SRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSH-MSGTSSSSGMKSSSGLGSSGS 1254
S P S L SP+ G + K PIS G + T SS + G +
Sbjct: 537 SLP---SLSLESPLL---GAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPR 590
Query: 1255 LSQK----TPPSSNSCTASSSSFSSSGSSMS 1281
LS+ T PSS++ +++ FS +GS+ S
Sbjct: 591 LSRSPFTSTLPSSSASISTTQVFSLAGSTFS 621
Score = 39.3 bits (90), Expect = 0.030
Identities = 86/352 (24%), Positives = 134/352 (38%), Gaps = 28/352 (7%)
Query: 952 GSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKP--GKRSRTPSNDGK----S 1005
GS+ T G ++ T+ S SG L S G SRT G S
Sbjct: 483 GSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLS 542
Query: 1006 KDKPPKRKKADTEGKSP-SHSSS--NRPFTPPTSTGGSKSPGSAG--RSQTPPGVATPPI 1060
+ P T K P SHS + P S+ PG++ R P +T P
Sbjct: 543 LESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPS 602
Query: 1061 PKITIQIPKGTVMVGK----PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKS 1116
+I + + G PS+H T G+V+ S++ SH+ S + S
Sbjct: 603 SSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTS 662
Query: 1117 SKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSP----ITKHGLS-SGSSSTK 1171
+ SS S +SS + + + S+ PG++ + K G +G + +
Sbjct: 663 PQESLSSMSPISS-LPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIVE 721
Query: 1172 MKPQGKPSSLMNPSLSKP--NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSG- 1228
M N L + +++ R + +L+ P +P P++ P G
Sbjct: 722 MLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGL 781
Query: 1229 ---SGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSS-NSCTASSSSFSSS 1276
+G S TS S KSS GL +S S S + P S S ++SS SF S+
Sbjct: 782 PPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHST 833
Score = 33.9 bits (76), Expect = 1.3
Identities = 37/142 (26%), Positives = 54/142 (38%), Gaps = 28/142 (19%)
Query: 1149 SGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPS-------------H 1195
+G PG + SS S ST P GK S ++ SLS + P H
Sbjct: 772 NGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFH 831
Query: 1196 SRPP--------GGSDKLASP--MKPVPGTPPSSKAKSPISSGSGGSHMS-----GTSSS 1240
S PP + LA P P+P P + ++P ++G G M+ G + S
Sbjct: 832 STPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGS 891
Query: 1241 SGMKSSSGLGSSGSLSQKTPPS 1262
G+ + LG + P S
Sbjct: 892 GGLPLNGLLGGLNGAAAPNPAS 913
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 75.1 bits (183), Expect = 5e-13
Identities = 101/402 (25%), Positives = 144/402 (35%), Gaps = 69/402 (17%)
Query: 967 KTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSS 1026
KT K EG + PG +K R R PS K + A E +P+
Sbjct: 2306 KTSKDTGEGKDGGTAGSEEPG--AKARGRGRKPSAKAKGD------RAATLEEGNPTDEV 2357
Query: 1027 SNRPFT-PPTSTGGSKS----------------PGSAGRSQTPPGVATPPIPKITIQIPK 1069
+ P P+ST GSK P S PP + P P+ ++P
Sbjct: 2358 PSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPA 2417
Query: 1070 GTV------MVGKPSSHSQYTSSGSVSSSGSKS---------------HHSHSSSSSSSA 1108
++ P++ + + + SG+K H +S S A
Sbjct: 2418 PATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKA 2477
Query: 1109 STSGKMKSSKSEGS-SSSKLSSSMYSSQGSSGSSQSK------NSSQSGGKPGSS-PITK 1160
+ ++ G K S+ S ++GSS+ K +PG
Sbjct: 2478 KEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFED 2537
Query: 1161 HGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPG------ 1214
G + + G S + S S + S S S GS+ G
Sbjct: 2538 SGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT 2597
Query: 1215 -----TPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTAS 1269
+ SS+A SP SS S S S +SSSS SSS SS S S + SS+S ++S
Sbjct: 2598 GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2657
Query: 1270 SSSFSSSGSSMSSSQNQHGSSKGK----SPSRNKKPSLTAVI 1307
SSS SSS SS SSS SS +P+ PS A +
Sbjct: 2658 SSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAAL 2699
Score = 69.3 bits (168), Expect = 3e-11
Identities = 98/456 (21%), Positives = 151/456 (33%), Gaps = 42/456 (9%)
Query: 1044 GSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSS 1103
G GR PP KI P ++V S+ TS + G + S
Sbjct: 2267 GDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDT--GEGKDGGTAGSEE 2324
Query: 1104 SSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGS-SPITKHG 1162
+ A G+ S+K++G ++ L + + S + SS G K P+ K
Sbjct: 2325 PGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRA 2384
Query: 1163 LSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPS-SKA 1221
+ + +P P + S P P P + +P+ +P T P KA
Sbjct: 2385 KAPKARPAPPQPSPAPPAFT----SCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKA 2440
Query: 1222 KSPISSGSGGSHMSGTSSS-------SGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS 1274
++ SG+ G G + G+ S + +L + P + S S
Sbjct: 2441 RAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLS 2500
Query: 1275 SSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTN 1334
+ S GSS+ K+P T G ++P G +
Sbjct: 2501 -----LGSYPPAAGSSEPKAPWPK----------------ATDGDLAQEPGPGLTFEDSG 2539
Query: 1335 SSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIII 1394
+ P ++ G E S S S+S SS S + E + G
Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGT-- 2597
Query: 1395 SKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSP 1454
GG A P SS +SS + S S S+ S S S S
Sbjct: 2598 ----GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2653
Query: 1455 AYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLP 1490
+ + + S S S SS + +S SSDD P P
Sbjct: 2654 SSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAP 2689
Score = 68.6 bits (166), Expect = 5e-11
Identities = 86/369 (23%), Positives = 134/369 (36%), Gaps = 48/369 (13%)
Query: 968 TQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS 1027
T+ + K+ S GP + + ++G + K K K+A + P
Sbjct: 2433 TRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGW 2492
Query: 1028 NRPFT-------PPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS- 1079
P + PP + GS P + T +A P P +T + G P S
Sbjct: 2493 QEPKSLLSLGSYPPAA--GSSEPKAPWPKATDGDLAQEPGPGLTFEDS------GNPKSP 2544
Query: 1080 -HSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEG----------------- 1121
+Q G+ S S S SSS SSS+S+S S++EG
Sbjct: 2545 DKAQAEQDGAEESESSSS----SSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
Query: 1122 ---SSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKP 1178
++SS+ +S SS SS SS S +SS S SS SS SSS+
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSS------SSSSSSSSSSSSSSS 2654
Query: 1179 SSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTS 1238
SS + S S + S S + S P P PS++A P + ++
Sbjct: 2655 SSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSA 2714
Query: 1239 SSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRN 1298
S G K+ + + Q T P A + S + + + + + PS
Sbjct: 2715 HSPGKKTPAPQPQAPP-PQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVE 2773
Query: 1299 KKPSLTAVI 1307
+P + A +
Sbjct: 2774 NRPKIAAFL 2782
Score = 58.5 bits (140), Expect = 5e-08
Identities = 56/205 (27%), Positives = 81/205 (39%), Gaps = 11/205 (5%)
Query: 1120 EGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPS 1179
E S + K + Q + S+S +SS SG SS SS S T+ + +G +
Sbjct: 2536 EDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSS-----SSSSSGSETEGEEEGDKN 2590
Query: 1180 SLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSS 1239
N S + SR + +S + SS + S SS S S S +SS
Sbjct: 2591 GDGGCGTGGRNCSAASSRAASPASSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSS 2644
Query: 1240 SSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNK 1299
SS SSS SS S S + SS+S T S SS + + S++ P++
Sbjct: 2645 SSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT 2704
Query: 1300 KPSLTAVIDKLKHGVVTSGPGGEDP 1324
K + A G T P + P
Sbjct: 2705 KQAGKARPSAHSPGKKTPAPQPQAP 2729
Score = 34.3 bits (77), Expect = 0.98
Identities = 26/102 (25%), Positives = 38/102 (37%), Gaps = 4/102 (3%)
Query: 965 KEKTQKRVKEGNGTSNSTLSGPGL--DSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSP 1022
+EK KR E G + +GPGL PG + GK+ PP + +
Sbjct: 947 EEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKA 1006
Query: 1023 SHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKIT 1064
+ P + +P S +PP + PP P IT
Sbjct: 1007 KVIQKLEDVSKPPAYAYPATPSS--HPTSPPPASPPPTPGIT 1046
Score = 32.3 bits (72), Expect = 3.7
Identities = 45/242 (18%), Positives = 81/242 (33%), Gaps = 32/242 (13%)
Query: 951 SGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPP 1010
SGS ++ G E + + NG G + + + S+ S
Sbjct: 2565 SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSS 2624
Query: 1011 KRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKG 1070
+ + S S SSS+ + +S+ S S S+ S +
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------------- 2665
Query: 1071 TVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKM-----KSSKSEGSSSS 1125
SS S T S SS ++ + ++ S+ A+ K K+ S S
Sbjct: 2666 ------SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGK 2719
Query: 1126 KLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPS 1185
K + + + + +Q+G K S P + G+ ++ K Q PS P
Sbjct: 2720 KTPAPQPQAPPPQPTQPLQPKAQAGAK--SRPKKREGVHLPTTKELAKRQRLPSVENRPK 2777
Query: 1186 LS 1187
++
Sbjct: 2778 IA 2779
>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1230
Score = 73.9 bits (180), Expect = 1e-12
Identities = 107/413 (25%), Positives = 156/413 (37%), Gaps = 22/413 (5%)
Query: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK 1144
+SG + SGS +SSS+S AST + S +S S S ++S +SG+S
Sbjct: 9 ASGVSTPSGS----GWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPS 64
Query: 1145 NSSQSGGKPGSSPI-TKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNI-------SPSHS 1196
NS + + I + G +S S+S P S +PS S +I SPS S
Sbjct: 65 NSGWASFSASWASIPSDSGWASPSASWASTP--SDSGWASPSASGASIPSDSGWASPSVS 122
Query: 1197 RPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSG-TSSSSGMKSSSGLGSSGSL 1255
S ASP TP S SP +S + S SG S S+ S S +S S
Sbjct: 123 GASIPSAFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSA 182
Query: 1256 SQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVV 1315
S + PS + + S + S +S +SS + G + S S S + +
Sbjct: 183 SGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGAST 242
Query: 1316 TSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSS 1375
+S G P + ST+ +S S S + S S + SS +
Sbjct: 243 SSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWA 302
Query: 1376 KKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPL 1435
S+S + + +S S S G +S S + SP
Sbjct: 303 SAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSDSGWASPS 362
Query: 1436 ISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRP 1488
SG++ + G S S S A S S SG+S S SPS+ P
Sbjct: 363 ASGASTSSDSGWASPSASWA-------SPSASGASTPSDSGWASPSASGASMP 408
Score = 73.2 bits (178), Expect = 2e-12
Identities = 113/423 (26%), Positives = 157/423 (37%), Gaps = 53/423 (12%)
Query: 981 STLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGS 1040
ST SG G S + TPSN G + SPS S ++ P S G
Sbjct: 13 STPSGSGWASSSASGASTPSNSGWA---------------SPSASGASIP-----SDSGW 52
Query: 1041 KSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSH 1100
SP ++G S TP IP + +S + S +S +
Sbjct: 53 ASPSASGAS-TPSNSGWASFSASWASIPSDSGWASPSASWASTPSDSGWASPSASGASIP 111
Query: 1101 SSSSSSSASTSG-KMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPIT 1159
S S +S S SG + S+ S+S S+ S S +S + SS SG S+ T
Sbjct: 112 SDSGWASPSVSGASIPSAFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSASWT 171
Query: 1160 KHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSD-KLASPMKPVPGTPPS 1218
S SSS S +PS+ +SPS S SD AS S
Sbjct: 172 SPSASCASSSASGASTPSDSGWASPSVFW--VSPSTSWASSPSDFGWASTPSDSGWASSS 229
Query: 1219 SKAKSPISSGSGGSHMSG----------TSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTA 1268
+ SP +SG+ S SG TS+S SS +S S S + S +
Sbjct: 230 ASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVC 289
Query: 1269 SSSSFSSSGSSMSSSQNQHGSSKGK---------------SPSRNKKPSLTAVIDKLKHG 1313
S+S++SS +S +S+ + GSS S S PS + G
Sbjct: 290 PSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSASG 349
Query: 1314 V-VTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSV 1372
V TS G P G ST+S S S + + G SD + S SG+S+
Sbjct: 350 VSTTSDSGWASP--SASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASGASM 407
Query: 1373 DSS 1375
S+
Sbjct: 408 PSA 410
Score = 62.8 bits (151), Expect = 3e-09
Identities = 104/411 (25%), Positives = 158/411 (38%), Gaps = 31/411 (7%)
Query: 1065 IQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSS 1124
+ P G+ +S + S+ +S + S S +S S SG S S +S
Sbjct: 12 VSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASF 71
Query: 1125 SKLSSSMYSSQG--SSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLM 1182
S +S+ S G S +S + S SG S+ SG +S + PS+
Sbjct: 72 SASWASIPSDSGWASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSGASIPSAFW 131
Query: 1183 -NPSLSKPNI-------SPSHSRPPGGSDK-LASPMKPVPGTPPSSKAKSPISSGSGGSH 1233
+PS S + SPS S SD ASP T PS+ S +SG+
Sbjct: 132 ASPSASGASTPSDSGWASPSASWASTSSDSGWASPS--ASWTSPSASCASSSASGASTPS 189
Query: 1234 MSGTSSSSGM---KSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1290
SG +S S S+S S + PS + +SS+S S +S +S+ + G +
Sbjct: 190 DSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGASTSSDSGWA 249
Query: 1291 KGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGE 1350
SPS + + T+ S D + G S+S SS S
Sbjct: 250 ---SPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPS 306
Query: 1351 FQGKREKSDKDKSKVSTSG-SSVDSSKKTSESKNVGSTGVAKIIISKHDGG--SPSIKAK 1407
G S S +S SG +S +S ++ S + ++ A + + D G SPS
Sbjct: 307 DSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSDSGWASPSASGA 366
Query: 1408 VTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTP 1458
T G +S S ++ SP SG++ + G S S S A P
Sbjct: 367 STSSDSGWAS---------PSASWASPSASGASTPSDSGWASPSASGASMP 408
Score = 58.2 bits (139), Expect = 6e-08
Identities = 89/335 (26%), Positives = 139/335 (41%), Gaps = 42/335 (12%)
Query: 972 VKEGNGTSNSTLSGPGLDSK-----PGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSS 1026
+ +G ++ ++SG + S + TPS+ G + P A T S S
Sbjct: 110 IPSDSGWASPSVSGASIPSAFWASPSASGASTPSDSGWAS---PSASWASTSSDSGWASP 166
Query: 1027 SNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHS-QYTS 1085
S +P S S + G++ S + G A+P + + T PS T
Sbjct: 167 SASWTSPSASCASSSASGASTPSDS--GWASPSV----FWVSPSTSWASSPSDFGWASTP 220
Query: 1086 SGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKS-EGSSSSKLSSSMYSSQGSSGSSQSK 1144
S S +S S S S S+S +S++S SG S S +S+S+ S+S S SS +S
Sbjct: 221 SDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDS 280
Query: 1145 NSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDK 1204
+S SG S+ +S S+S P SS P++S + + G
Sbjct: 281 ITSDSGWVCPSA-----SWASSSASWASAPSDSGSS-------SPSVSRASTLSVSGWAS 328
Query: 1205 LASPMKPVPGTPPSSKAKSPISSGSGGSHMSG--TSSSSGMKSSSGLGSSGSL-SQKTPP 1261
++ S A +P SG SG T+S SG S S G+S S S P
Sbjct: 329 FSA-----------SGASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTSSDSGWASP 377
Query: 1262 SSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPS 1296
S++ + S+S S+ S +S + G+S +PS
Sbjct: 378 SASWASPSASGASTPSDSGWASPSASGASMPSAPS 412
Score = 44.3 bits (103), Expect = 0.001
Identities = 67/262 (25%), Positives = 95/262 (36%), Gaps = 29/262 (11%)
Query: 1232 SHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSK 1291
S SG S+ SG SG SS + TP +S + S+S S S +S + G+S
Sbjct: 7 SRASGVSTPSG----SGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGAS- 61
Query: 1292 GKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEF 1351
+PS + S +A + S G P S + +S P S +
Sbjct: 62 --TPSNSGWASFSA-----SWASIPSDSGWASP-------SASWASTPSDS--GWASPSA 105
Query: 1352 QGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGST--------GVAKIIISKHDGGSPS 1403
G SD + S SG+S+ S+ S S + ST A + D G S
Sbjct: 106 SGASIPSDSGWASPSVSGASIPSAFWASPSASGASTPSDSGWASPSASWASTSSDSGWAS 165
Query: 1404 IKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDS 1463
A T +S S + SP + +P S A TP +
Sbjct: 166 PSASWTSPSASCASSSASGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGW 225
Query: 1464 ESESGSSIAEKSYQNSPSSDDG 1485
S S S I+ + S SSD G
Sbjct: 226 ASSSASCISPSASGASTSSDSG 247
Score = 40.8 bits (94), Expect = 0.010
Identities = 106/432 (24%), Positives = 155/432 (35%), Gaps = 55/432 (12%)
Query: 811 SSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAA-GSPSSDSPTNHFFHDGVDFNPDL 869
S SG + S+ + + +P A + +D+ SPS+ + F+
Sbjct: 16 SGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASW 75
Query: 870 LNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTV 929
+ S SG+ +S D+ G+AS + + +P D+G + +
Sbjct: 76 ASIPSDSGWASPSASWASTPSDS----GWASPSASGASIP---SDSGWASPSVSGASIPS 128
Query: 930 DFSIISVAGKALAPADLMEHHSGSQGPLL----TTGDLG-KEKTQKRVKEGNGTSNSTLS 984
F A A P+D SG P T+ D G + ++S+ S
Sbjct: 129 AFWASPSASGASTPSD-----SGWASPSASWASTSSDSGWASPSASWTSPSASCASSSAS 183
Query: 985 GPGLDSKPGKRSRT-----PSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGG 1039
G S G S + PS S P A T S +SS+ P+++G
Sbjct: 184 GASTPSDSGWASPSVFWVSPSTSWASS--PSDFGWASTPSDS-GWASSSASCISPSASGA 240
Query: 1040 SKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHS 1099
S S S S + V+T T S +SS S S S S
Sbjct: 241 STSSDSGWASPSASWVST------------STSRASTSSDSGWASSSASWDSITSDSGWV 288
Query: 1100 HSSSS--SSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSP 1157
S+S SSSAS + S S S S+ S+ S S +S + S SG
Sbjct: 289 CPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGW------ 342
Query: 1158 ITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPP 1217
T H +SG S+T S +PS S + S S S S ASP TP
Sbjct: 343 -TSHS-ASGVSTT------SDSGWASPSASGASTS-SDSGWASPSASWASPSASGASTPS 393
Query: 1218 SSKAKSPISSGS 1229
S SP +SG+
Sbjct: 394 DSGWASPSASGA 405
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 72.4 bits (176), Expect = 3e-12
Identities = 99/358 (27%), Positives = 145/358 (40%), Gaps = 29/358 (8%)
Query: 951 SGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPP 1010
SGS L T KT + G S SG S P ++ + + G+ K P
Sbjct: 261 SGSAADLFT-------KTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPS 313
Query: 1011 KRKKADTEGKSPSHSSSNRPFTP--PTSTGG---SKSPGSAGRSQTPPGVATPPIPKITI 1065
E S + S S FT P + G + SP S GR G +P + +
Sbjct: 314 GGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESR--GFQSPCLECAEV 371
Query: 1066 QIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSS 1125
+ + S + S S +S+ S SH S S + +S + +S + S S
Sbjct: 372 KKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSR 431
Query: 1126 KLSSSMYSSQGS--SGSSQSKNS-SQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLM 1182
S S S + S S SS+S+ S S S P K+ + + + + S
Sbjct: 432 SPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSY- 490
Query: 1183 NPSLSKPNISPSHSRPPGGSDKLASPMK-PVPGTPPSSKAKSPISSGSGGSHMSGTSSSS 1241
+P + SPSH + ++ S K P+P PS P SSGS S S SSSS
Sbjct: 491 SPMRKRRRDSPSHLE----ARRITSARKRPIPYYRPS-----PSSSGSLSSTSSWYSSSS 541
Query: 1242 GMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGS-SKGKSPSRN 1298
+S S S S+ S ++SSSS S S S S S+++ S S+ +S SR+
Sbjct: 542 SRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRS 599
Score = 67.0 bits (162), Expect = 1e-10
Identities = 127/590 (21%), Positives = 203/590 (34%), Gaps = 124/590 (21%)
Query: 1012 RKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGT 1071
R+ T G S SH ++ TPP S+ G K + R + + P P
Sbjct: 84 RELGATRGHSASH---DKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSP---------- 130
Query: 1072 VMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSM 1131
V K S ++ S S K HS SS S K S+S S +
Sbjct: 131 VKKKKKKSSKKHKRRRSFSK---KRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHR 187
Query: 1132 YSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNI 1191
S+ S SS+S+ SS G SP K + + S + +L K +
Sbjct: 188 CPSR--SQSSESRPSSCESRHRGRSP-----------EEGQKSRRRHSRRCSKTLCKDSP 234
Query: 1192 SPSHSRPPG----------------GSDKLASPMKPVPGTPPSSKAKSP-ISSGSGGSHM 1234
SRPP GS A +S+ +S SG+ S
Sbjct: 235 EAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSP 294
Query: 1235 SGTSSSSGMKSSSGLGS-SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSS--QNQHGSSK 1291
T +SS GS SG LS+ +S + + S +SF++S + +N +S+
Sbjct: 295 PSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSR 354
Query: 1292 GKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEF 1351
G+ + P L ++K + P+ G S+ +S+ SS H+
Sbjct: 355 GRESRGFQSPCLECA--EVKKSSLVPSTARSSPMKGCSRSSSYASTR--SSSHS------ 404
Query: 1352 QGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQ 1411
+S ++ + S SS+K S S+ SPS +K +
Sbjct: 405 ----SRSPNPRASPRYTQSRSTSSEKRSYSR------------------SPSYSSKSGKR 442
Query: 1412 KPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSI 1471
P S R +P + R SPS + P Y+ ++ +
Sbjct: 443 SPPSRSSRSRR-----------------SPSYSRYSPSRERDPKYSEKDSQQRERERARR 485
Query: 1472 AEKSY-------QNSPS-------SDDGIRPLPEY-----------STEKHKKHKKEKKK 1506
+SY ++SPS + RP+P Y ST +
Sbjct: 486 RRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSA 545
Query: 1507 VKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADR 1556
+ R R R + R + ++ + S S+SP +S S + + S R
Sbjct: 546 SRSYSRSRSRSRSRRRSRTRTSSSSS-SRSPSPGSRSRSRSRSRSRSRSR 594
Score = 61.2 bits (147), Expect = 7e-09
Identities = 97/379 (25%), Positives = 141/379 (37%), Gaps = 29/379 (7%)
Query: 950 HSGSQGPLLTT--GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKP------------GKR 995
HS S LT GK+K +K ++ S+S P K K+
Sbjct: 92 HSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKK 151
Query: 996 SRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQ---TP 1052
R S+ KSK + KR K + + P S +R P+ + S+S S+ S+
Sbjct: 152 RRHSSSSPKSKRRDEKRHKKQSRSR-PRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRS 210
Query: 1053 PGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSG 1112
P + + + K T+ P + S S + G S + S S+A
Sbjct: 211 PEEGQKSRRRHSRRCSK-TLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFT 269
Query: 1113 KMKS--SKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSS- 1169
K S + S G S S + SS S+ +S +++ Q G P L+SG++S
Sbjct: 270 KTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSD 329
Query: 1170 -----TKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSP 1224
T PQ K + L N S + + P VP T SS K
Sbjct: 330 SGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGC 389
Query: 1225 ISSGSGGSHMSG--TSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSS 1282
S S S S +S S ++S S S S + S S + SS S S S SS
Sbjct: 390 SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSS 449
Query: 1283 SQNQHGSSKGKSPSRNKKP 1301
+ S SPSR + P
Sbjct: 450 RSRRSPSYSRYSPSRERDP 468
Score = 52.0 bits (123), Expect = 5e-06
Identities = 61/212 (28%), Positives = 91/212 (42%), Gaps = 18/212 (8%)
Query: 967 KTQKRVKEGNGTSNSTLS---GPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPS 1023
+ R + TS+ S P SK GKRS PS +S+ P + + + + P
Sbjct: 411 RASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRS-PPSRSSRSRRSPSYSRYSPSRERDPK 469
Query: 1024 HS---SSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSH 1080
+S S R S SP R +P + I K + +PS
Sbjct: 470 YSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSAR----KRPIPYYRPSP- 524
Query: 1081 SQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGS 1140
+SSGS+SS+ S +S SSS S+S S S S+S S ++ SSS S S GS
Sbjct: 525 ---SSSGSLSSTSS--WYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGS 579
Query: 1141 -SQSKNSSQSGGKPGSSPITKHGLSSGSSSTK 1171
S+S++ S+S + S + S SS+ +
Sbjct: 580 RSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
Score = 38.1 bits (87), Expect = 0.068
Identities = 100/449 (22%), Positives = 158/449 (35%), Gaps = 47/449 (10%)
Query: 1119 SEGSSSSKLSSSMYSSQ-GSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGK 1177
++ S KL + + G++ + K + G G S L+ SS K + K
Sbjct: 55 AQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKK 114
Query: 1178 PSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGT 1237
+ K S S+S P K S S K K S H S +
Sbjct: 115 STR------KKRRRSSSYSPSPVKKKKKKS----------SKKHKRRRSFSKKRRHSSSS 158
Query: 1238 SSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSR 1297
S S S +K+ + S S SS S SS +++H +G+SP
Sbjct: 159 PKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQ--SSESRPSSCESRH---RGRSPEE 213
Query: 1298 NKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSG-GEFQGKRE 1356
+K + +H S +D + Q S+ S P+ +S G G
Sbjct: 214 GQK-------SRRRHSRRCSKTLCKDSPEAQ---SSRPPSQPLQMLGYLSARGVITGSGS 263
Query: 1357 KSD---KDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQ-K 1412
+D K S ++TS +++ + ST + + GSPS + +
Sbjct: 264 AADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELN 323
Query: 1413 PGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIA 1472
G +S G +S +N G+ L + S R S +SP L+ SS+
Sbjct: 324 SGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGF-QSPC-----LECAEVKKSSLV 377
Query: 1473 EKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPES 1532
+ ++SP G Y++ + H + R +K+S+S P
Sbjct: 378 PSTARSSPMK--GCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSY 435
Query: 1533 WSKSPISSDQSLSMTSNTILSADR--PSR 1559
SKS S S S S S R PSR
Sbjct: 436 SSKSGKRSPPSRSSRSRRSPSYSRYSPSR 464
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 72.0 bits (175), Expect = 4e-12
Identities = 125/575 (21%), Positives = 198/575 (34%), Gaps = 48/575 (8%)
Query: 961 GDLGKEKTQKRVKEGNGTSNSTLSGPGLD-SKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
G+ +KT R G+ + S + G D S+ S + S D + +D+E
Sbjct: 394 GEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEA 453
Query: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
PS S+S P PPT+ + Q + K++ P +V PSS
Sbjct: 454 NEPSQSASPEPEPPPTN-----------KWQLDNWLNKVNPHKVS---PASSVDSNIPSS 499
Query: 1080 HSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSG 1139
Y G +G+ S+ S +S++T G+ + +GS S + Q S
Sbjct: 500 QG-YKKEGREQGTGN-SYTDTSGPKETSSATPGRDSKTIQKGSESGR------GRQKSPA 551
Query: 1140 SSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPP 1199
S S ++ GK K K++ + + S+ + SR P
Sbjct: 552 QSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKP 611
Query: 1200 GGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKT 1259
+ S +P T K KS S + T +SS S S S S +T
Sbjct: 612 NIKKESKSSPRP---TAEKKKYKSTSKSSQKSREIIETDTSS---SDSDESESLPPSSQT 665
Query: 1260 P--PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTS 1317
P P SN SS S K ++ +I K+ ++T
Sbjct: 666 PKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTR 725
Query: 1318 GPG-----GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSV 1372
PG E P + V + + K +GKR+ ++D ++ S S
Sbjct: 726 IPGKPYKETEPPKGEKKNVPEKHTRE--AQKQASEKVSNKGKRKHKNEDDNRASESKKPK 783
Query: 1373 DSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYG 1432
K ++ K + +K +K PS V + P G R SS
Sbjct: 784 TEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSS---- 839
Query: 1433 SPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEY 1492
S S ++ K GS +S S + + S S + EK +PSS P
Sbjct: 840 SLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEK----APSSSSNCP--PSA 893
Query: 1493 STEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHS 1527
T K ++ K D++ D KK H+
Sbjct: 894 PTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHN 928
Score = 65.9 bits (159), Expect = 3e-10
Identities = 140/573 (24%), Positives = 214/573 (37%), Gaps = 84/573 (14%)
Query: 1029 RPFTPPTSTGGSK----SPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHS-QY 1083
+P PP++ S G Q+ P P + + + G S HS Q
Sbjct: 79 KPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSS---GLQSGHSSQR 135
Query: 1084 TSSGSVS---SSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSS--------SKLSSSMY 1132
TS+GS S SSG + ++S SS+ G+ S S+ SS S L+SS
Sbjct: 136 TSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHS 195
Query: 1133 SSQGSSGSSQSKNSSQSGGKPGS---SPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKP 1189
S G+ S+ S+S P + SP ++ SSG ST Q P SLM+ S S
Sbjct: 196 RSHGNDHHSKEHQRSKSPRDPDANWDSP-SRVPFSSGQHST----QSFPPSLMSKSNSML 250
Query: 1190 NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGL 1249
++ RP G + + + + S S +H++ S +S
Sbjct: 251 QKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASAS 310
Query: 1250 GSSG-------SLSQKTPPSSNS----CTASSSSFSSSGSSMSSSQNQHGSSKGKSPSR- 1297
G ++ PP + C S F S G K +PS+
Sbjct: 311 GDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKT 370
Query: 1298 -NKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVST-NSSSHPMSSKHNMSGGEFQGKR 1355
N S + + D LK + GE D M ST S+S P S HN G + R
Sbjct: 371 SNGHQSKSMLKDDLKLS-SSEDSDGEQDCDKTMPRSTPGSNSEP--SHHNSEGAD--NSR 425
Query: 1356 EKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIK-------AKV 1408
+ S S+SGS +S +S+S+ + A S P+ K KV
Sbjct: 426 DDSSSHSGSESSSGSDSESESSSSDSEANEPSQSA----SPEPEPPPTNKWQLDNWLNKV 481
Query: 1409 TLQKPG-ESSGEGLRPQMASSKNYGSPLISGSTPKHERG-SPSHSKSPAYTPQNLDSESE 1466
K SS + P K G +G++ G + S +P + + SE
Sbjct: 482 NPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSE 541
Query: 1467 SGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSH 1526
SG + Q SP+ D +T++ KK+ KK + + R
Sbjct: 542 SG-----RGRQKSPAQSDS-------TTQRRTVGKKQPKKAEKAAAEEPRG--------- 580
Query: 1527 SIKPESWSKSPISSDQSLSMTSNTILSADRPSR 1559
+K E S++P+ D + SM S+ +A + SR
Sbjct: 581 GLKIE--SETPV--DLASSMPSSRHKAATKGSR 609
Score = 65.1 bits (157), Expect = 5e-10
Identities = 143/658 (21%), Positives = 240/658 (36%), Gaps = 95/658 (14%)
Query: 968 TQKRVKEGNGTSNSTLSGPG----LDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPS 1023
++K+ + G+ S S S PG + S SR+ ND SK+ +R K+ + +
Sbjct: 163 SRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEH--QRSKSPRDPDANW 220
Query: 1024 HSSSNRPFTPPTSTGGSKSPGSAGRS----QTPPGVATP------PIPKI-----TIQIP 1068
S S PF+ + S P +S Q P P PK+ + Q
Sbjct: 221 DSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSH 280
Query: 1069 KGTVMVGKPSSHSQYT------------SSGSVS-------------------------S 1091
++ KPSS + T +SG VS +
Sbjct: 281 GNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKT 340
Query: 1092 SGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGG 1151
SK S S+ T G+ K +S+ S SM SS+ + Q
Sbjct: 341 EPSKFPFPTKESQQSNFGT-GEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCD 399
Query: 1152 K------PGSSPITKHGLSSGSSSTK---MKPQGKPSSLMNPSLSKPNISPSHSRPPGGS 1202
K PGS+ H S G+ +++ G SS + S S+ + S S + P S
Sbjct: 400 KTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQS 459
Query: 1203 DKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSS--SGMKSSSGLGSSGSLSQKTP 1260
P P PP++K + H +SS S + SS G G ++
Sbjct: 460 ------ASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEG--REQGT 511
Query: 1261 PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKG----KSPSRNKKPSLTAVIDKLKHGVVT 1316
+S + T+ SS+ S Q GS G KSP+++ + + K K
Sbjct: 512 GNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK-KQPKKA 570
Query: 1317 SGPGGEDPLDG---QMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVD 1373
E+P G + + +S SS+H + +G R+ + K +SK S ++
Sbjct: 571 EKAAAEEPRGGLKIESETPVDLASSMPSSRHKAA---TKGSRKPNIKKESKSSPRPTAEK 627
Query: 1374 SSKKTSESKNVGSTGVAKIIISKHDGG-SPSIKAKVTLQKPGESSGEGLRPQMASSK-NY 1431
K++ + S + + S D S S+ K ES+ ++P + ++
Sbjct: 628 KKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSF 687
Query: 1432 GSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPE 1491
+ + E SP Y P + + + I K Y+ + + +PE
Sbjct: 688 FRQRMFSPMEEKELLSPLSEPDDRY-PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPE 746
Query: 1492 YSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSN 1549
T + +K EK K K + ++ D D + S S KP++ K+ S + S+
Sbjct: 747 KHTREAQKQASEKVSNKGKRKHKNED---DNRASESKKPKTEDKNSAGHKPSSNRESS 801
Score = 62.0 bits (149), Expect = 4e-09
Identities = 166/769 (21%), Positives = 274/769 (35%), Gaps = 115/769 (14%)
Query: 631 PVSSMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICSGSNKTKKK 690
P SS +T++ P + + K N T Y P++ Q S P++ S+++
Sbjct: 227 PFSSGQHSTQSFPPSL-MSKSNSMLQKPTAY-VRPMDGQESME--PKLSSEHYSSQSHGN 282
Query: 691 KSSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLD-TPHITPAPSQCSTPP 749
+ L P H T+ + D + T P +T + C T P
Sbjct: 283 SMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEP 342
Query: 750 TTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRD 809
+ +P P Q S + G E+ PS
Sbjct: 343 SKFPFPTKESQQS-----------NFG---------TGEQKRYNPS-------------- 368
Query: 810 SSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDL 869
+S+GH ++ D+ +++ ++ D + +P S+S +H +G D + D
Sbjct: 369 KTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRS-TPGSNSEPSHHNSEGADNSRD- 426
Query: 870 LNSQSQSGF-GEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADT 928
+S S SG D S+S +D SQ+ + P K++ +N +
Sbjct: 427 -DSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEP-----PPTNKWQLDNWLNK 480
Query: 929 VDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGL 988
V+ +S A + + + SQG K + R ++G G S + SGP
Sbjct: 481 VNPHKVSPA------SSVDSNIPSSQG----------YKKEGR-EQGTGNSYTDTSGPKE 523
Query: 989 DSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGR 1048
S S TP D K+ K + + KSP+ S S T T G K P A +
Sbjct: 524 TS-----SATPGRDSKTIQKGSESGRG--RQKSPAQSDS----TTQRRTVGKKQPKKAEK 572
Query: 1049 SQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSA 1108
A P+ ++I T + + S +S ++ GS+ + S SS
Sbjct: 573 -------AAAEEPRGGLKIESETPV---DLASSMPSSRHKAATKGSRKPNIKKESKSSPR 622
Query: 1109 STSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKN---SSQSGGKPGS--SPITKHGL 1163
T+ K K KS SS K + + SS S +S++ SSQ+ P S +P+ +
Sbjct: 623 PTAEK-KKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSV 681
Query: 1164 SSGSS------STKMKPQGKPSSLMNPSLSKPNISPSH----SRPPGGSDKLASPMKPVP 1213
S + M+ + S L P P I +R PG K P K
Sbjct: 682 EEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPK--- 738
Query: 1214 GTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSF 1273
G + K + S K+ +S S KT +++ SS+
Sbjct: 739 GEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNR 798
Query: 1274 SSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVST 1333
SS S + ++ S G PS++ K +HG L +
Sbjct: 799 ESSKQSAAKEKDLLPSPAGPVPSKD---------PKTEHGSRKRTISQSSSLKSSSNSNK 849
Query: 1334 NSSSHPMSSKHNMSGGEFQGKREKSDKD-KSKVSTSGSSVDSSKKTSES 1381
+S +S + +GK S K+ K K +S S+ S T +S
Sbjct: 850 ETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDS 898
Score = 60.1 bits (144), Expect = 2e-08
Identities = 92/359 (25%), Positives = 139/359 (38%), Gaps = 63/359 (17%)
Query: 1211 PVPGTPPSSKAKSP---ISSGSGGSHMS--------GTSSSSGMKSSSGLGSSGSLSQKT 1259
P P PPS+ KS GGSH S S+S K SSGL SG SQ+T
Sbjct: 78 PKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGL-QSGHSSQRT 136
Query: 1260 PPSSNSCTASS------SSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHG 1313
S+S T SS S+++SGSS S + QHGS KS S
Sbjct: 137 SAGSSSGTNSSGQRHDRESYNNSGSS-SRKKGQHGSEHSKSRS----------------- 178
Query: 1314 VVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVD 1373
S PG VS+ +SSH S ++ E Q + D D + S S
Sbjct: 179 ---SSPG------KPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFS 229
Query: 1374 SSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGS 1433
S + +++S ++SK S S+ K T E + P++ SS++Y S
Sbjct: 230 SGQHSTQS-------FPPSLMSK----SNSMLQKPTAYVRPMDGQESMEPKL-SSEHYSS 277
Query: 1434 PLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYS 1493
S + + S +H Q LD+ + S ++ + S P P +
Sbjct: 278 QSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHS----WPPPLTA 333
Query: 1494 TEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPES--WSKSPISSDQSLSMTSNT 1550
K + K K+ + ++K+ + K + SKS + D LS + ++
Sbjct: 334 IHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDS 392
>gi|118572603 ubinuclein 1 [Homo sapiens]
Length = 1134
Score = 71.6 bits (174), Expect = 6e-12
Identities = 71/256 (27%), Positives = 108/256 (42%), Gaps = 31/256 (12%)
Query: 1068 PKGTVMVGKPSSHSQ-YTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSS-KSEGSSSS 1125
P + G +S +Q + S + + +K H S+ ++S S SS K+ SSSS
Sbjct: 822 PFANKLQGPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGGLSASSSSSHKTPASSSS 881
Query: 1126 KLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKP-QGKPSSLMNP 1184
LS SS S KN+ P +S I+KHG+SSGSSS+ P Q S + P
Sbjct: 882 ALSHPAKPHSVSSAGSSYKNN------PFASSISKHGVSSGSSSSGGTPVQSSVSGSLVP 935
Query: 1185 SLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMK 1244
+ P++ + SRP P S+ K P+S ++ + G
Sbjct: 936 GIQPPSVGQATSRP----------------VPSSAGKKMPVS-----QKLTLVAPPGGPN 974
Query: 1245 SSSGLGSSGSLSQKTPPS-SNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSL 1303
S G+ G T PS S +S +S +S S + GSS SP ++ P L
Sbjct: 975 GDSSGGTQGVAKLLTSPSLKPSAVSSVTSSTSLSKGASGTVLLAGSSLMASPYKSSSPKL 1034
Query: 1304 TAVIDKLKHGVVTSGP 1319
+ + G++T P
Sbjct: 1035 SGAMSSNSLGIITPVP 1050
Score = 41.2 bits (95), Expect = 0.008
Identities = 72/311 (23%), Positives = 115/311 (36%), Gaps = 45/311 (14%)
Query: 954 QGPLLTTGDLGKEKTQ--KRVKEGNGTSNST-LSGPGLDSKPGKRSRTPSNDGKSKDKPP 1010
QGP + + Q K +G G S + GL + +TP++ + P
Sbjct: 828 QGPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGGLSASSSSSHKTPASSSSALSHPA 887
Query: 1011 KRKKADTEGKSPSHSSSNRPFTPPTS----TGGSKSPG-----SAGRSQTPPGVATPPIP 1061
K + G S N PF S + GS S G S+ PG+ P +
Sbjct: 888 KPHSVSSAGSS----YKNNPFASSISKHGVSSGSSSSGGTPVQSSVSGSLVPGIQPPSVG 943
Query: 1062 KIT-----------IQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAST 1110
+ T + + + +V P + +S G+ + + S S+ SS ++
Sbjct: 944 QATSRPVPSSAGKKMPVSQKLTLVAPPGGPNGDSSGGTQGVAKLLTSPSLKPSAVSSVTS 1003
Query: 1111 SGKMKSSKSEGSSSSKL--SSSMYSS--QGSSGSSQSKNSSQSGGKPGSSPITKHGLSSG 1166
S +S S+G+S + L SS+ +S + SS SS S G PI H LS
Sbjct: 1004 S----TSLSKGASGTVLLAGSSLMASPYKSSSPKLSGAMSSNSLGIITPVPIPVHVLSFS 1059
Query: 1167 SSSTKMKPQGKPSSLMNPS-------LSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSS 1219
+ S+ K + + P+ L ++ HS PP + P VP P S
Sbjct: 1060 ADSSAKAGVSKDAIVTGPAPGSFHHGLGHSLLAGLHSSPPHAA---PLPHAAVPTHIPQS 1116
Query: 1220 KAKSPISSGSG 1230
+ G G
Sbjct: 1117 LPGASQLHGKG 1127
Score = 32.0 bits (71), Expect = 4.9
Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 1477 QNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKS 1525
Q S S DD I+ + S +K +K K+ +K+K K +D DK++ KKS
Sbjct: 171 QASESEDDFIKEKKKKSPKK-RKLKEGGEKIKKKKKDDTYDKEKKSKKS 218
>gi|118572601 ubinuclein 1 [Homo sapiens]
Length = 1134
Score = 71.6 bits (174), Expect = 6e-12
Identities = 71/256 (27%), Positives = 108/256 (42%), Gaps = 31/256 (12%)
Query: 1068 PKGTVMVGKPSSHSQ-YTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSS-KSEGSSSS 1125
P + G +S +Q + S + + +K H S+ ++S S SS K+ SSSS
Sbjct: 822 PFANKLQGPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGGLSASSSSSHKTPASSSS 881
Query: 1126 KLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKP-QGKPSSLMNP 1184
LS SS S KN+ P +S I+KHG+SSGSSS+ P Q S + P
Sbjct: 882 ALSHPAKPHSVSSAGSSYKNN------PFASSISKHGVSSGSSSSGGTPVQSSVSGSLVP 935
Query: 1185 SLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMK 1244
+ P++ + SRP P S+ K P+S ++ + G
Sbjct: 936 GIQPPSVGQATSRP----------------VPSSAGKKMPVS-----QKLTLVAPPGGPN 974
Query: 1245 SSSGLGSSGSLSQKTPPS-SNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSL 1303
S G+ G T PS S +S +S +S S + GSS SP ++ P L
Sbjct: 975 GDSSGGTQGVAKLLTSPSLKPSAVSSVTSSTSLSKGASGTVLLAGSSLMASPYKSSSPKL 1034
Query: 1304 TAVIDKLKHGVVTSGP 1319
+ + G++T P
Sbjct: 1035 SGAMSSNSLGIITPVP 1050
Score = 41.2 bits (95), Expect = 0.008
Identities = 72/311 (23%), Positives = 115/311 (36%), Gaps = 45/311 (14%)
Query: 954 QGPLLTTGDLGKEKTQ--KRVKEGNGTSNST-LSGPGLDSKPGKRSRTPSNDGKSKDKPP 1010
QGP + + Q K +G G S + GL + +TP++ + P
Sbjct: 828 QGPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGGLSASSSSSHKTPASSSSALSHPA 887
Query: 1011 KRKKADTEGKSPSHSSSNRPFTPPTS----TGGSKSPG-----SAGRSQTPPGVATPPIP 1061
K + G S N PF S + GS S G S+ PG+ P +
Sbjct: 888 KPHSVSSAGSS----YKNNPFASSISKHGVSSGSSSSGGTPVQSSVSGSLVPGIQPPSVG 943
Query: 1062 KIT-----------IQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAST 1110
+ T + + + +V P + +S G+ + + S S+ SS ++
Sbjct: 944 QATSRPVPSSAGKKMPVSQKLTLVAPPGGPNGDSSGGTQGVAKLLTSPSLKPSAVSSVTS 1003
Query: 1111 SGKMKSSKSEGSSSSKL--SSSMYSS--QGSSGSSQSKNSSQSGGKPGSSPITKHGLSSG 1166
S +S S+G+S + L SS+ +S + SS SS S G PI H LS
Sbjct: 1004 S----TSLSKGASGTVLLAGSSLMASPYKSSSPKLSGAMSSNSLGIITPVPIPVHVLSFS 1059
Query: 1167 SSSTKMKPQGKPSSLMNPS-------LSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSS 1219
+ S+ K + + P+ L ++ HS PP + P VP P S
Sbjct: 1060 ADSSAKAGVSKDAIVTGPAPGSFHHGLGHSLLAGLHSSPPHAA---PLPHAAVPTHIPQS 1116
Query: 1220 KAKSPISSGSG 1230
+ G G
Sbjct: 1117 LPGASQLHGKG 1127
Score = 32.0 bits (71), Expect = 4.9
Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 1477 QNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKS 1525
Q S S DD I+ + S +K +K K+ +K+K K +D DK++ KKS
Sbjct: 171 QASESEDDFIKEKKKKSPKK-RKLKEGGEKIKKKKKDDTYDKEKKSKKS 218
>gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]
Length = 1992
Score = 71.2 bits (173), Expect = 7e-12
Identities = 88/352 (25%), Positives = 142/352 (40%), Gaps = 32/352 (9%)
Query: 960 TGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPG--KRSRTPSNDGKSKDKPPKRKKADT 1017
TG + K+ + VK + + P KP + + +PS K K K++ D
Sbjct: 60 TGQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPKALQHTESPSETNKPHSK-SKKRHLDQ 118
Query: 1018 EGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKP 1077
E + S S P TS ++ G+ G S++ T ++ G+ G
Sbjct: 119 EQQLKSAQS------PSTSKAHTRKSGATGGSRSQKRKRT---ESSCVKSGSGSESTGAE 169
Query: 1078 SSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGS 1137
++ T S S++ +K+ S + SSS+ASTS SS + S+SS + QG
Sbjct: 170 ERSAKPTKLASKSATSAKAGCSTITDSSSAASTS---SSSSAVASASSTVPPGARVKQGK 226
Query: 1138 SGSSQSKNSSQSGGKPGSSPITKHGLSSGSSS-----TKMKPQGKPSSLMNPSLSKPNIS 1192
+ ++ S S P S K +G SS + P+ SL LS P S
Sbjct: 227 DQNKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPK---VSLPKTKLSLPGSS 283
Query: 1193 PSHSRPPGGSD---KLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGL 1249
S + PG S KLAS K S A+ P S +G+ +S+ + SGL
Sbjct: 284 KSETSKPGPSGLQAKLASLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASTS-RRGSGL 342
Query: 1250 GSSGSLSQK-----TPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPS 1296
G G+ + P SN +SS+ + + ++ ++ G+S S
Sbjct: 343 GKRGAAEARRQEKMADPESNQEAVNSSAARTDEAPQGAAGAVGMTTSGESES 394
Score = 48.1 bits (113), Expect = 7e-05
Identities = 83/381 (21%), Positives = 134/381 (35%), Gaps = 45/381 (11%)
Query: 1011 KRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKG 1070
+R + +T G P S +S P R+ T T +PK K
Sbjct: 14 RRSQRNTAGAQPQDDSIGGRSCSSSSAVIVPQPEDPDRANTSERQKTGQVPK------KD 67
Query: 1071 TVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSS 1130
K S+ Y + S SS+ H+ S S + K K + K
Sbjct: 68 NSRGVKRSASPDYNRTNSPSSAKKPKALQHTESPSETNKPHSKSKKRHLDQEQQLK---- 123
Query: 1131 MYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPN 1190
S+QS ++S++ + K G + GS S K K SS +
Sbjct: 124 ---------SAQSPSTSKAHTR-------KSGATGGSRSQKRKRT--ESSCVK------- 158
Query: 1191 ISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLG 1250
S S S G ++ A P K + S+KA + S + + +SSS+ +SS +
Sbjct: 159 -SGSGSESTGAEERSAKPTKLASKSATSAKAGCSTITDSSSAASTSSSSSAVASASSTVP 217
Query: 1251 SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL 1310
+ Q + + S+SS S SS Q++ G S + P ++ KL
Sbjct: 218 PGARVKQGKDQNKARRSRSASSPSPRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKL 277
Query: 1311 KHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGS 1370
S PG + G S + K E S + ++ T+GS
Sbjct: 278 ------SLPGSSKSETSKPGPSGLQAKLASLRKSTKKRSESPPAELPSLRRSTRQKTTGS 331
Query: 1371 SVDSSKKTSESKNVGSTGVAK 1391
+S++ S +G G A+
Sbjct: 332 CASTSRRGS---GLGKRGAAE 349
Score = 33.1 bits (74), Expect = 2.2
Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)
Query: 1420 GLRPQMAS----SKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKS 1475
G +PQ S S + S +I +R + S + P+ +S S+ + +
Sbjct: 22 GAQPQDDSIGGRSCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYN 81
Query: 1476 YQNSPSSDDGIRPLP--EYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIK 1529
NSPSS + L E +E +K H K KK+ D+++ + K+H+ K
Sbjct: 82 RTNSPSSAKKPKALQHTESPSETNKPHSKSKKRHLDQEQQLKSAQSPSTSKAHTRK 137
>gi|120953251 neuron navigator 3 [Homo sapiens]
Length = 2363
Score = 71.2 bits (173), Expect = 7e-12
Identities = 142/663 (21%), Positives = 243/663 (36%), Gaps = 62/663 (9%)
Query: 747 TPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTP 806
T P+ + P + ++ R+ +S D +D+ D++ E +G
Sbjct: 774 TDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDL--DMSSEVD-----------VGGY 820
Query: 807 LRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFN 866
+ D G S T + + T+ N YT + I D A +S HD V +
Sbjct: 821 MSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTA---TSRDIIQRGVHD-VTVD 876
Query: 867 PDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFAS-QALNTLGVPMLGGDNGETKFKGNNQ 925
D + S G ++ + DD +S + + + VP T+ + +++
Sbjct: 877 ADSWDDSSSVSSG---LSDTLDNISTDDLNTTSSVSSYSNITVP----SRKNTQLRTDSE 929
Query: 926 ADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSG 985
+ + P + + H + G T E +K ++ + + + T S
Sbjct: 930 KRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSW 989
Query: 986 P-GLDSKPGKRSRTPSNDGKSKDKPPKRK---KADTEGKSPSHSSSNRPFTPPTSTGGSK 1041
G+ ++ G SR + G S K P + KA +GK+P SS + +
Sbjct: 990 RRGMSAQGGAPSRQKA--GTSALKTPGKTDDAKASEKGKAPLKGSSLQ-----------R 1036
Query: 1042 SPGSAGRSQTPPGVATPP-IPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGS----KS 1096
SP AG+S G P I + T G S + TSSG+ +SGS K
Sbjct: 1037 SPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKI 1096
Query: 1097 HHSHSSSSSSSASTSGKMKSSKSEGSS----SSKLSSSMYSSQGSSGSSQSKNSSQSGGK 1152
S + S+A + S+++ SSK + S S SS S + G +
Sbjct: 1097 PKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHR 1156
Query: 1153 PGSSPITKH--GLSSGSSSTKMKPQGKPSSLMNPSLS---------KPNISPSHSRPPGG 1201
+S I + S+G++++K++ K S + ++ K +S S S G
Sbjct: 1157 SSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSG 1216
Query: 1202 SDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPP 1261
S K + G + S + + + +G KS+S + G S P
Sbjct: 1217 SPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMP 1276
Query: 1262 SSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGG 1321
S ++ A S S S S + G S SP NK LT + L H + +S
Sbjct: 1277 SPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASV 1336
Query: 1322 EDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSES 1381
G + + N SS SK S S+ +S GS + T E
Sbjct: 1337 HSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEV 1396
Query: 1382 KNV 1384
+++
Sbjct: 1397 QSL 1399
Score = 57.0 bits (136), Expect = 1e-07
Identities = 88/433 (20%), Positives = 151/433 (34%), Gaps = 45/433 (10%)
Query: 1089 VSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQ 1148
V ++GS S +S+ + + + + +K ++ S Q SSG + +
Sbjct: 254 VPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPS 313
Query: 1149 SGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLM----------NPSLS----KPNISPS 1194
+ G+P +S I S S M + +S M +P+ S KP +S
Sbjct: 314 TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
Query: 1195 HSRPPGGSDKLASPMKPVPG----TPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLG 1250
P G + K V PP + P G S + G S G
Sbjct: 374 VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
Query: 1251 SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQH-GSSKGK----SPSRNKKPSLTA 1305
S + S K P A S + S+ S + + + K K P + +K +T
Sbjct: 434 GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
Query: 1306 VIDK--------LKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREK 1357
+ K + G T+ E + G+ S P + K +S G K
Sbjct: 494 MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVP-TVKQTISPGSTASK--- 549
Query: 1358 SDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTL-QKPGES 1416
+ +K + + S SK + K S+ A + + SPS +T+ Q G+S
Sbjct: 550 -ESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQS 608
Query: 1417 SGEGLRPQMASSKNYGSPLISGSTP------KHERGSPSHSKSPAYTPQNLD-SESESGS 1469
+G G Q+ + + P + P G+ S +P +D S S++
Sbjct: 609 TGNG-AVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAK 667
Query: 1470 SIAEKSYQNSPSS 1482
E+ P +
Sbjct: 668 QCLEEISGEDPET 680
Score = 51.2 bits (121), Expect = 8e-06
Identities = 97/405 (23%), Positives = 143/405 (35%), Gaps = 99/405 (24%)
Query: 975 GNGTSNSTLSGPGLDSKPG---KRSRTPSNDGKSKDKPPKRKKADTEGK------SPSHS 1025
G+ +S S++ G + R P+ G + P + D E + S S S
Sbjct: 1154 GHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVS 1213
Query: 1026 SSNRPFTPPTSTG-----GSKSPGS------------------AGRSQTPPGVATPPIPK 1062
S P + PTS G + PGS G+S + P T +
Sbjct: 1214 LSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPN--TEGVKS 1271
Query: 1063 ITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGS 1122
++ T + + S S + +GS+ S+G S S + S T+ + S S S
Sbjct: 1272 SSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLAS 1331
Query: 1123 SSSKLSS----------SMYSSQGSSG---SSQSKNSSQSGGKPGSSPITKHGLSSGSSS 1169
S + + S +M SS S S QS S + + P++ HG SG ++
Sbjct: 1332 SPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTT 1391
Query: 1170 TKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGS 1229
+ Q S LM + +S S D+ P K + TP S +A
Sbjct: 1392 GTHEVQ---SLLMRTGSVRSTLSESMQL-----DRNTLPKKGLRYTPSSRQANQEEGKEW 1443
Query: 1230 GGSHMSG-----------------TSSSSGMKSSSGLGSSGSLSQKTPPS-----SNSCT 1267
SH +G +SS++G S L S +LSQ P SNS
Sbjct: 1444 LRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIP 1503
Query: 1268 ASSSSF----------------------SSSGSSMSSSQNQHGSS 1290
A SSF S SGS S + HGSS
Sbjct: 1504 AQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSS 1548
Score = 36.2 bits (82), Expect = 0.26
Identities = 52/230 (22%), Positives = 78/230 (33%), Gaps = 31/230 (13%)
Query: 974 EGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTP 1033
E G ++ SG +S P + SK+ K+ + K + N+ T
Sbjct: 422 EMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCT- 480
Query: 1034 PTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSG 1093
+ P + Q +A KI IPKG+ S SS + G
Sbjct: 481 -------EKPVKEEKDQVTE-MAPKKTSKIASLIPKGSKTTAA-KKESLIPSSSGIPKPG 531
Query: 1094 SKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKP 1153
SK +K + S GS++SK S +++GS S SK +
Sbjct: 532 SKVP---------------TVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASA 576
Query: 1154 GSSPITKHGLSSGSSS-----TKMKPQGKPSSLMNPSLSKPNISPSHSRP 1198
S P G +G +S T Q S N ++ P HS P
Sbjct: 577 SSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQ-QQQHSHP 625
Score = 33.1 bits (74), Expect = 2.2
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK 1144
SS SVSS S + SHSS S + + S K K S S+L SS + G S++
Sbjct: 1669 SSESVSSINSAT--SHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPP 1726
Query: 1145 NSSQ------SGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSL 1181
+S P S + + GS+S MKP S++
Sbjct: 1727 SSHSDIEELTDSSLPASPKLPHNAGDCGSAS--MKPSQSASAI 1767
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 70.9 bits (172), Expect = 9e-12
Identities = 129/591 (21%), Positives = 218/591 (36%), Gaps = 83/591 (14%)
Query: 992 PGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTS-TGGSKSPGSAGRSQ 1050
PGK + + GK D +++D++G++P+ +S + PP ++SP AG +
Sbjct: 839 PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP--AGPAA 896
Query: 1051 TPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAST 1110
TP P+ S ++ +SS S + + ++ T
Sbjct: 897 TPAQAQAASTPR----------KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 946
Query: 1111 SGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGK-PGSSPITKHGLS----S 1165
+ +S + SSS SS+ S G Q ++Q K P S P+T+ L
Sbjct: 947 MPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQK 1006
Query: 1166 GSSSTKMKPQGKPSSLMNPSLSK-PNISP-SHSRPPGGSDKLASPMKP----VPGTPPSS 1219
S + + +PSS ++ ++ P SP S S G++KL P P P SS
Sbjct: 1007 ASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESS 1066
Query: 1220 KAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSS 1279
S S GS G G KS+ LG TP + + +++ SS
Sbjct: 1067 DDSEDSSDSSSGSEEDG-EGPQGAKSAHTLGP-------TPSRTETLVEETAAESSEDDV 1118
Query: 1280 MSSSQNQHGS--SKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSS 1337
++ SQ+ + G +P+ ++ T +D V+S +D DG+ ++
Sbjct: 1119 VAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPS--VSSTLAAKDDPDGKQEAKPQQAA 1176
Query: 1338 HPMSSK---HNMSGGEFQGKREKSDKDKSKVSTSGSSVDSS------------------- 1375
+S K + G K K K S ++ S+
Sbjct: 1177 GMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQA 1236
Query: 1376 --------------KKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEG- 1420
KK ++ S + K G P+ + + +K +GEG
Sbjct: 1237 SVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGG 1296
Query: 1421 ---LRPQMASSKNYGSPL---ISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEK 1474
+ P+ S+ + G SG K ++G S A + E + G E
Sbjct: 1297 EASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGA--KDEPEEELQKGMGTVEG 1353
Query: 1475 SYQNSPSSDDGIRPLPEYSTEKHKKHKKEK-KKVKDKDRDRDRDKDRDKKK 1524
Q++P S + + +K KK KK+K KK KD + K + KKK
Sbjct: 1354 GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKK 1404
Score = 62.8 bits (151), Expect = 3e-09
Identities = 196/1014 (19%), Positives = 347/1014 (34%), Gaps = 151/1014 (14%)
Query: 543 ASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFS-KVSQN 601
AS+P G P G T P G + + + + K +S E+ S +
Sbjct: 226 ASAPAKG-----TPGKGATPA----PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET 276
Query: 602 PILTSLLQITGNGG-STIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTL 660
P +LLQ +G S +G++ P +P ++ A K P + +D +
Sbjct: 277 PAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS 336
Query: 661 YGSSPLERQNSSSGSPR---MEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDV 717
S E + + P ++ + S K+ P P+ Q ++ +
Sbjct: 337 SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE 396
Query: 718 DSQNPIFDVNMTADTL------------DTPHITPAPSQCSTPPTTYPQPVPHPQPSIQR 765
DS++ + + + L +P + PA + P PVP +
Sbjct: 397 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPG-----K 451
Query: 766 MVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDV 825
+ + S +G D S +EE+S S+ + P P ++ S ++
Sbjct: 452 VGPATPSAQVGKWEEDSESS-SEESSD--SSDGEVPTAVAPAQEKSLG----------NI 498
Query: 826 FQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDE 885
Q +P P A ++ P + NS+S +E
Sbjct: 499 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMD--------------NSESS--------EE 536
Query: 886 SSQSGDNDDFKGF--ASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISV--AGKAL 941
SS S D+++ A+QA L +P +T + + V + AG A
Sbjct: 537 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 596
Query: 942 APADLMEHHSG-SQGPLLTTG-----DLGKEKTQKRVKEGNGTSNSTLSGPGLDSKP--- 992
+PA +G +Q P + D +EKT V G S G GL K
Sbjct: 597 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKS----VGKGLQVKAASV 652
Query: 993 --------GKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTP----------- 1033
G P G + + K+ D+E S +P
Sbjct: 653 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ 712
Query: 1034 ----------PTSTGGSKSPG-----SAGRSQTPPGVATPPIPK-----ITIQIPKGTVM 1073
P++ G +PG +A Q P PP+ + + P
Sbjct: 713 AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS 772
Query: 1074 VGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYS 1133
VGK + + +G SGS S S A T ++K S + L+ + S
Sbjct: 773 VGKAVATAAQAQTGPEEDSGSSE---EESDSEEEAETLAQVKPSGKTHQIRAALAPAKES 829
Query: 1134 SQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGK-PSSLMNPSLSKPN-I 1191
+ + + + S + G SGSSS + G+ P+++ + + KP I
Sbjct: 830 PRKGAAPTPPGKTGPSAAQAGKQD------DSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
Query: 1192 SPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGS 1251
+R P G P S+ K+ S + S S + + ++ L
Sbjct: 884 FVDPNRSPAG-----PAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTP 938
Query: 1252 SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHG-SSKGKSPSRNKK-----PSLTA 1305
+ T P+++ A +S + + SS SS+ G +G + +KK P A
Sbjct: 939 GIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQA 998
Query: 1306 VIDKLKHGVVTSGP--GGEDPLDG-QMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDK 1362
+ L + P P G V T ++ P S+ G K + + +
Sbjct: 999 ALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ 1058
Query: 1363 SKVS--TSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEG 1420
+ + +S S DSS +S S+ G G + G +PS + + ESS +
Sbjct: 1059 ATKAPESSDDSEDSSDSSSGSEEDGE-GPQGAKSAHTLGPTPSRTETLVEETAAESSEDD 1117
Query: 1421 -LRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAE 1473
+ P + Y +P ++ + + + +P SP+ + + G A+
Sbjct: 1118 VVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK 1171
Score = 49.7 bits (117), Expect = 2e-05
Identities = 86/407 (21%), Positives = 134/407 (32%), Gaps = 67/407 (16%)
Query: 1101 SSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITK 1160
S+S SS + +++K+ +S SS + + SS ++K ++ GK G+S
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS---- 138
Query: 1161 HGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSK 1220
M ++ N K SP S P + L S + P
Sbjct: 139 -----------MPHPATGKTVANLLSGK---SPRKSAEPSANTTLVSETEEEGSVPAFGA 184
Query: 1221 AKSP--ISSGSGGSHMSGTSSSSG----------------MKSSSGLGSSGSLSQKTPPS 1262
A P +S+G S TSSSS S+ G+ G + PP
Sbjct: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPG 244
Query: 1263 SNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGE 1322
AS + SS + S+ ++P+ K K S P E
Sbjct: 245 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA-KALLQAKASGKTSQVGAASAPAKE 303
Query: 1323 DPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESK 1382
P G + ++ GKRE+ + S+ S S + K S
Sbjct: 304 SPRKGAAPAPPGKTGPAVAKAQ-------AGKREEDSQSSSEESDSEEEAPAQAKPS--- 353
Query: 1383 NVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPK 1442
G +P ++A K ES +G P A + G K
Sbjct: 354 ----------------GKAPQVRAASAPAK--ESPRKGAAP--APPRKTGPAAAQVQVGK 393
Query: 1443 HERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPL 1489
E S S S+ + L + + + KS Q P+S G+ PL
Sbjct: 394 QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 440
Score = 45.4 bits (106), Expect = 4e-04
Identities = 98/506 (19%), Positives = 166/506 (32%), Gaps = 87/506 (17%)
Query: 987 GLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSA 1046
G +KPG S + D S+D + D E K+ R + P G+
Sbjct: 183 GAAAKPGMVSAGQA-DSSSEDTSSSSDETDVEVKASEKILQVRAASAPAK-------GTP 234
Query: 1047 GRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSS 1106
G+ TP PP GK + + T +G S+S SS S
Sbjct: 235 GKGATP----APP---------------GKAGAVASQTKAGKPEED-SESSSEESSDSEE 274
Query: 1107 SASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSG 1166
+ + +K+ G +S ++S + + + ++G + K S
Sbjct: 275 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 334
Query: 1167 SSSTKMKPQGKPSSLMNPSLSKPNI----SPSHSRPPGGSDKLASPMKPVPGTPPSSKAK 1222
SSS + + + + PS P + +P+ P G+ A P K P K
Sbjct: 335 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP-APPRKTGPAAAQVQVGK 393
Query: 1223 SPISSGSGGSHMS-----------------GTSSSSGMKSSSGLGSSGSLSQKTPPSS-N 1264
S S G S S+ G+G G + PP
Sbjct: 394 QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG 453
Query: 1265 SCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDP 1324
T S+ S SSS+ SS G+ P+ P+ + + TS P P
Sbjct: 454 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTA-VAPAQEKSLGNILQAKPTSSPAKGPP 512
Query: 1325 LDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSES--- 1381
+ PM + + + + +D +++ + + + + K ++
Sbjct: 513 QKAGPVAVQVKAEKPMDNSESS-----EESSDSADSEEAPAAMTAAQAKPALKIPQTKAC 567
Query: 1382 -KNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGST 1440
K +T AK+ +V Q P ++ A+S SP ++G T
Sbjct: 568 PKKTNTTASAKV-----------APVRVGTQAPRKAG-------TATSPAGSSPAVAGGT 609
Query: 1441 PKHERGSPSHSKSPAYTPQNLDSESE 1466
+ S S +S DSE E
Sbjct: 610 QRPAEDSSSSEES--------DSEEE 627
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 70.5 bits (171), Expect = 1e-11
Identities = 192/896 (21%), Positives = 319/896 (35%), Gaps = 105/896 (11%)
Query: 599 SQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMA-GNTK--NHPMLMNLLKDNPAQ 655
S +P++TS + + SSPTP T P+S+ + G+T P+ + +
Sbjct: 3073 SNSPVVTS---------TEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIS 3123
Query: 656 DFST--LYGSSPLERQNSSSGSPRM-EICSGSNKTKKKKSSRL---PPEKPKHQTEDDFQ 709
ST + S+P+ + SP E S T + S+ L P + +D
Sbjct: 3124 TLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSED-- 3181
Query: 710 RELFSMDVDSQNPIFDV-----NMTADTLDTPHITPAPSQCSTPPTTYP---QPVPHPQP 761
L + VD+ P+ + TA+ P T PS+ TP T+ P PV +
Sbjct: 3182 STLSATPVDTSTPVTTSTEATSSTTAEGTSIP--TSTPSEGMTPLTSVPVSNTPVASSEA 3239
Query: 762 SIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDD---CPAIGTPLRDSSSSGHSQS 818
SI + S+ + S E + +P+++ P P+ ++ + S
Sbjct: 3240 SILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETS 3299
Query: 819 TLFDSDVFQTNNNENPYTDPADL--IADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQS 876
TL + T+ Y+ + IAD P+S + F+ + S S
Sbjct: 3300 TLSTTPA-DTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEAS 3358
Query: 877 GFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISV 936
D S+ + + + A T +P G T + T V
Sbjct: 3359 TLSTTPVDTSTPVTTSTEASLSPTTAEGT-SIPTSSPSEGTTPL-ASMPVSTTPVVSSEV 3416
Query: 937 AGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRS 996
+ P D L+TT + + + EG ST S S
Sbjct: 3417 NTLSTTPVD--------SNTLVTTST--EASSSPTIAEGTSLPTSTTSEGSTPLSIMPLS 3466
Query: 997 RTP--SNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPG 1054
TP S++ + P SP++SS P T+ S +AG TP
Sbjct: 3467 TTPVASSEASTLSTTPVDTSTPVTTSSPTNSS------PTTAEVTSMPTSTAGEGSTP-- 3518
Query: 1055 VATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKM 1114
+P T V SS + S+ V S+ + S +SSS ++ +
Sbjct: 3519 ---------LTNMPVSTTPVA--SSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMR 3567
Query: 1115 KSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKP 1174
S+ SEGSSS L++ + SS + S S S+ S + S+P+T S+ S+ST P
Sbjct: 3568 MSTPSEGSSS--LTTMLLSSTYVTSSEASTPSTPSVDR--STPVT---TSTQSNSTPTPP 3620
Query: 1175 Q------GKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPIS-- 1226
+ PS + P P + S + G+ P + + SP++
Sbjct: 3621 EVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPE 3680
Query: 1227 -------SGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQ--KTPPSSNSCTASSSSFSSSG 1277
+ S GS T S + +S GS+ S + P + S A SSS +
Sbjct: 3681 GTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDS 3740
Query: 1278 SSMSSSQNQHGSSKGKSP----------SRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDG 1327
++MS S S+ G + + PS+ +V + + G L+G
Sbjct: 3741 TTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEG 3800
Query: 1328 --QMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVG 1385
M +ST S + + +S E S TS + S+K S S
Sbjct: 3801 TTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAE 3860
Query: 1386 STGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTP 1441
T + I S+ ++ TL + P + +S + + STP
Sbjct: 3861 VTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTP 3916
Score = 69.3 bits (168), Expect = 3e-11
Identities = 207/1031 (20%), Positives = 379/1031 (36%), Gaps = 155/1031 (15%)
Query: 550 MTTGNNPMSGTTTPTNTFPGG-------PITTLFNMSMSIKDRHESVGHGEDFSKVSQNP 602
+++ P GT+ PT+T+ G P+ T S +I S +S P
Sbjct: 1315 VSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAI-------------SILSTTP 1361
Query: 603 ILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNP--AQDFSTL 660
+ S T SSPT T P S+ + T P+ + P + + STL
Sbjct: 1362 VDNSTPVTTSTEAC---SSPTTSEGTSMPNSNPSEGTT--PLTSIPVSTTPVVSSEASTL 1416
Query: 661 YGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQ 720
++P++ S+ G+ E S + +P P + + L S+ V S
Sbjct: 1417 -SATPVD--TSTPGTTSAEATSSPTTAE---GISIPTSTPS-----EGKTPLKSIPV-SN 1464
Query: 721 NPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVT 780
P+ N A TL T P ++P T P P+ + +S+ +T
Sbjct: 1465 TPV--ANSEASTLST-----TPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALT 1517
Query: 781 DILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPAD 840
I AS ++ PA+ + + S S T D QT+ T
Sbjct: 1518 SIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTS 1577
Query: 841 LIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFAS 900
L SS++ T + ++S++Q E ++ G +S
Sbjct: 1578 LPVSTMLVVSSEANT---------LSTTPIDSKTQVTASTEASSSTTAEG--------SS 1620
Query: 901 QALNT--LGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLL 958
++T G P+L T + +A T+ + + + ++ + ++G +
Sbjct: 1621 MTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSM 1680
Query: 959 TTGDLGKEKT-----QKRVKEGNGTSNSTLSGPGLD-SKPGKRSRTPSNDGKSKDKPPKR 1012
T + +T R ++ STLS +D S P S + + +
Sbjct: 1681 PTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMP 1740
Query: 1013 KKADTEGKSP------------SHSSSNRPFTP-------PTSTGGSKSPGSAGRSQTP- 1052
+EG +P S +S TP TST + SP +A + P
Sbjct: 1741 NSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPT 1800
Query: 1053 --------PGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSS 1104
P +TP + T+ S+S +S +VSSS + + + ++S
Sbjct: 1801 STLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATS 1860
Query: 1105 S----SSASTSGKMKSSKSEGSSSSKLSS---------SMYSSQGSS-----GSSQSKNS 1146
+ S+A TS + ++ S ++ LS+ + Y+ SS GSS ++
Sbjct: 1861 TPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTST 1920
Query: 1147 SQSGGKPGSS-PITKHGLSS---GSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGS 1202
+ G P +S P++ ++S + ST + P + + + S P + S P
Sbjct: 1921 PREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAY 1980
Query: 1203 DKLASPM--KPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLG----SSGSLS 1256
+ ++P+ P+ T S S +S+ + T+S+ G S + G + + S
Sbjct: 1981 SEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPS 2040
Query: 1257 QKTPPSSNSCTASSSSFSSSGSSMSS----SQNQHGSSKGKSPSRNKKPSLTAVIDKLKH 1312
++T P + +++ SS G+++S+ S+ Q +S S S + S
Sbjct: 2041 ERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGS---------- 2090
Query: 1313 GVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGK-REKSDKDKSKVSTSGSS 1371
+ S P PL + +ST + P +S + + + ++ S + T G+S
Sbjct: 2091 SMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTS 2150
Query: 1372 VDSSKKTSE-----SKNVGSTGVAKIIIS-----KHDGGSPSIKAKVTLQKPGESSGEGL 1421
+ +S + S V +T VA IS D +P + P S G +
Sbjct: 2151 MQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM 2210
Query: 1422 ---RPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQN 1478
P S+ P+ + E + S + TP +E+ S + AE +
Sbjct: 2211 PTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 2270
Query: 1479 SPSSDDGIRPL 1489
+ + +G PL
Sbjct: 2271 TSTLSEGTTPL 2281
Score = 68.6 bits (166), Expect = 5e-11
Identities = 227/1120 (20%), Positives = 398/1120 (35%), Gaps = 218/1120 (19%)
Query: 522 TPALSLIAETVEDMVKKNLPPASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMS 581
TP S T+ N P ++ ++ GT+ P +T P T L ++ +S
Sbjct: 1700 TPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTS-EGTSMPNST-PSEGTTPLTSIPVS 1757
Query: 582 IKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMA-GNTK 640
S + S +S PI TS T + SSPT T P S+++ G T
Sbjct: 1758 TTPVLSS-----EASTLSATPIDTSTPVTTSTEAT---SSPTTAEGTSIPTSTLSEGMTP 1809
Query: 641 --NHPMLMNLLKDNPAQDFST--LYGSSPLERQNSSSGSPR-MEICSGSNKTKKKKSSRL 695
+ P+ L+ ++ A ST + +SP+ + S SP E S + T + S+ L
Sbjct: 1810 LTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTAL 1869
Query: 696 PPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQ- 754
+ P+ + + +T TPA + STP TTY Q
Sbjct: 1870 -----------------------TSIPVSTTTVASSETNTLSTTPAVT--STPVTTYAQV 1904
Query: 755 ------------PVPHPQ---------PSIQRMVRLSSSDSIGPDVTDILSDIA--EEAS 791
P P+ P V S +++ + D + + +AS
Sbjct: 1905 SSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQAS 1964
Query: 792 KLPSTSD----DCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAG 847
P+T+D PA +S S + + S+ + + PA + +
Sbjct: 1965 SSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSS 2024
Query: 848 SPSSDSPTNHFFHD---------GVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGF 898
SP++ T+ G+ + L+ S + D +Q ++ +
Sbjct: 2025 SPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSS 2084
Query: 899 ASQALNTL-------GVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHS 951
A+ +++ G P+L T + +A T+ + + + ++
Sbjct: 2085 ATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPI 2144
Query: 952 GSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPK 1011
++G + T +T + T ++ + L + P S +N +++ P
Sbjct: 2145 PTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTT 2204
Query: 1012 RKKADTEGKSPSHSSSNRPFTP-PTSTGGSKSPGSAGRSQTPPGVATP----------PI 1060
+ +PS S+ PFT P ST + ++ S TP +TP P
Sbjct: 2205 SEGTSMPTSTPSEGST--PFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPT 2262
Query: 1061 PKITIQIPKGTVMVGK------PSSHS-------QYTSSGSVSSSGSKSHHSHSSSSSSS 1107
IP T+ G P SH+ S+ V S+ + + +SS +
Sbjct: 2263 TAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPT 2322
Query: 1108 ASTSGKMKSSKSEGSSS-----------SKLSSSMYSSQGSSGSSQSKNSSQSGGKP--- 1153
A + S+ SEG++ + +S S+ + S+ SQ+G P
Sbjct: 2323 AEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTA 2382
Query: 1154 ------------GSSPITKHGLS--------SGSSSTKMKPQGKPSSLMNPSLSKPNISP 1193
GS+P+T +S + + ST P + + S P +
Sbjct: 2383 DDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAE 2442
Query: 1194 SHSRPPGGSDKLASPM--KPVPGTP---------------------PSSKAKS------- 1223
S P + +P+ PV TP S++A S
Sbjct: 2443 GTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAED 2502
Query: 1224 ---PISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSS---- 1276
PIS+ S GS + +S + ++ S TP SNS +S+ SSS
Sbjct: 2503 IVVPISTASEGSTL---LTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSA 2559
Query: 1277 -GSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGV--ST 1333
G+SM +S GS+ +S + KP ++ L P+D + V ST
Sbjct: 2560 EGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTL----------STTPVDTSIPVTTST 2609
Query: 1334 NSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSK---KTSESKNVGSTGV- 1389
+SS P ++K S+VSTS +S+ S +SE+ + +T V
Sbjct: 2610 ETSSSPTTAKDT----------SMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVD 2659
Query: 1390 AKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPS 1449
+ +++ G S S P + GE P ++ + L++ S E + S
Sbjct: 2660 TRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTP--LTNILVSTTLLANS----EASTLS 2713
Query: 1450 HSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPL 1489
+ TP +E+ S + AE + + DG PL
Sbjct: 2714 TTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPL 2753
Score = 67.4 bits (163), Expect = 1e-10
Identities = 202/987 (20%), Positives = 353/987 (35%), Gaps = 135/987 (13%)
Query: 559 GTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGSTI 618
GT+ PT+ P T L +M +S S + +S P+ TS T S
Sbjct: 2443 GTSIPTSP-PSEGTTPLASMPVSTTPVVSS-----EAGTLSTTPVDTSTPMTTSTEAS-- 2494
Query: 619 GSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRM 678
SSPT P+S+ + + + + + STL ++P++ S SP +
Sbjct: 2495 -SSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTL-STTPVD-----SNSPVV 2547
Query: 679 EICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHI 738
S+ + + +P T + L SM V S P+ + A TL T
Sbjct: 2548 TSTEISSSATSAEGTSMPTS-----TYSEGSTPLRSMPV-STKPL--ASSEASTLST--- 2596
Query: 739 TPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSD 798
P S P TT + P + + +S+ + +T IL AS ST
Sbjct: 2597 --TPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLS 2654
Query: 799 DCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNN---NENPYTD---PADLIADAAGSPSSD 852
P L +S+ S T + T+ P T+ L+A++ S S
Sbjct: 2655 TTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLST 2714
Query: 853 SPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQ-SGDNDDFKGFASQALNTLGVPML 911
+P VD + + S S S + S +D S ++TL V
Sbjct: 2715 TP--------VDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPV--- 2763
Query: 912 GGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKR 971
+++A TV + + + + + ++ + T + T
Sbjct: 2764 ----------ASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLT 2813
Query: 972 VKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRK------KADTEGKS---- 1021
N T ++ L + P S + K+ P + +EG +
Sbjct: 2814 SMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTS 2873
Query: 1022 --------PSHSSSNRPFTP-------PTSTGGSKSPGSA-GRSQ---TPPGVATPPIPK 1062
S +S TP TST GS SP +A G S TP V+TP
Sbjct: 2874 IPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSI 2933
Query: 1063 ITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGS 1122
+ +P S+ T + +S+ + S + + +S ST G+ ++ + S
Sbjct: 2934 LVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMS 2993
Query: 1123 SSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGL-------SSGSSSTKMKPQ 1175
S+ +S +S S + + + + SSP T G S GS+ P
Sbjct: 2994 VSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPV 3053
Query: 1176 GKPSSLMNPSLSKPNISPSHSRPPG-GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSH- 1233
+ + P S + +P S P S +++S P GT PIS+ S GS
Sbjct: 3054 ST-TPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGT------SMPISTYSEGSTP 3106
Query: 1234 MSGTSSSSGMKSSSGLGSSGSLSQKTP-PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKG 1292
++G S+ +SS + + + T P + S A SS +S G+SM +S GS+
Sbjct: 3107 LTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGST-- 3164
Query: 1293 KSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQ 1352
P T ++ + +++ P+D V+T++ + ++ S
Sbjct: 3165 ---PLTYMPVSTMLVVSSEDSTLSA-----TPVDTSTPVTTSTEATSSTTAEGTS----- 3211
Query: 1353 GKREKSDKDKSKVSTSGSSVDSSKKTS---ESKNVGSTGVAKIIISKHDGGSPSIKAKVT 1409
+ TS S + TS + V S+ + + + D +P +
Sbjct: 3212 ------------IPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEA 3259
Query: 1410 LQKPGESSGEGL---RPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESE 1466
P + G + P S+ P+ + + E + S + + TP S++
Sbjct: 3260 SSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQAS 3319
Query: 1467 SGSSIAEKSYQNSPSSDDGIRPLPEYS 1493
S IA+ + + + +G PL S
Sbjct: 3320 SSPPIADGTSMPTSTYSEGSTPLTNMS 3346
Score = 65.5 bits (158), Expect = 4e-10
Identities = 265/1265 (20%), Positives = 427/1265 (33%), Gaps = 233/1265 (18%)
Query: 389 QGTLVSKITFQHPGRVPLILNLIRHQVAYNTLIGSCVKRTILKEDSPGLLQFEVC--PLS 446
+GT + T G PL + H + N+ S + T + +SP + V P
Sbjct: 1794 EGTSIPTSTLSE-GMTPLTSTPVSHTLVANSE-ASTLSTTPVDSNSPVVTSTAVSSSPTP 1851
Query: 447 ESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLYKGLSDALICTDDFIAKVVQRCMSIPV 506
S++ P S + V +T S + LS T + Q S P
Sbjct: 1852 AEGTSIATSTPSEGSTALTSIPVSTTTVASSET-NTLSTTPAVTSTPVTTYAQ-VSSSPT 1909
Query: 507 TMRAIRRKAETIQADTPALSLIAETVEDMVKKNLPPASSPGYGMTT--------GNNPMS 558
T T + P L+ I + + + S+ T ++P +
Sbjct: 1910 TADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTT 1969
Query: 559 --GTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGN--- 613
GT+ PT + G T L +M +S ++ + S +S P+ TS T
Sbjct: 1970 ADGTSMPTPAYSEGS-TPLTSMPLST-----TLVVSSEASTLSTTPVDTSTPATTSTEGS 2023
Query: 614 ------GGSTIGSSPTPPHHTPP----PVS-----SMAGNTKNHPML---MNLLKDNPAQ 655
GG++I +S TP T P PVS S GNT + + + A
Sbjct: 2024 SSPTTAGGTSIQTS-TPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEAS 2082
Query: 656 DFSTLYGSSPLERQNSSSGSPRME--------ICSGSNKT---------------KKKKS 692
+T GSS + S GSP + + S T + S
Sbjct: 2083 SSATAEGSS-MTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSS 2141
Query: 693 SRLPPEKPKHQTE--DDFQRELFSMDVDS----QNPIFDVNMTADTLDTPHITPAPSQCS 746
S +P E QT D + L SM V + + I ++ T TP +T + S
Sbjct: 2142 SPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTP-VTNSTEARS 2200
Query: 747 TPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTP 806
+P T+ +P PS S S P VT EAS L +T D TP
Sbjct: 2201 SPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTS-------EASTLSATPVDT---STP 2250
Query: 807 LRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFN 866
+ S+ + S +T + + P +++ +P + P +H
Sbjct: 2251 VTTSTEATSSPTTAEGTSI------------PTSTLSEGT-TPLTSIPVSH--------- 2288
Query: 867 PDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQA 926
L+ + S D ++ + + A T +P T +GN
Sbjct: 2289 -TLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGT-SMPT------STSSEGNTPL 2340
Query: 927 DTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGP 986
+ S VA + + L + + P+ T G T T
Sbjct: 2341 TRMPVSTTMVA--SFETSTLSTTPADTSTPVTTYSQAGSSPT-------------TADDT 2385
Query: 987 GLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSS-----SNRPFTPPTSTGGSK 1041
+ + TP P +A T +P +S S + PT+ G+
Sbjct: 2386 SMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTS 2445
Query: 1042 SPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSS--------- 1092
P S T P + P + GT+ + + T+S SSS
Sbjct: 2446 IPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVV 2505
Query: 1093 -------GSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSS--GSSQS 1143
GS S S++ AS S+ S+S ++S+ SS +S G+S
Sbjct: 2506 PISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMP 2565
Query: 1144 KNSSQSGGKP-GSSPITKHGLSSGSSSTKMK---PQGKPSSLMNPSLSKPNISPSHSRPP 1199
++ G P S P++ L+S +ST P + + S P + S P
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPI 2625
Query: 1200 GGSDKLASPM-------KPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSS 1252
++++ + PV + S+ + +P+ + + + +GTSSS S + +S
Sbjct: 2626 STPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTS 2685
Query: 1253 GSLSQKTP----------------------------PSSNSCTASSSSFSSSGSSMSSSQ 1284
+ TP P + S ASSS ++ G+SM S
Sbjct: 2686 TPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRIST 2745
Query: 1285 NQHGSSKGKS---------PSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQ---MGVS 1332
GS+ S S S TAV + V TS P + M S
Sbjct: 2746 PSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIP--VTTSTEASSSPTTAEVTSMPTS 2803
Query: 1333 TNS-SSHPMSS---KHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE-------S 1381
T S +S P++S H G + D S T+ + SS T+E +
Sbjct: 2804 TPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIST 2863
Query: 1382 KNVGSTGVAKIIISKHDGGSPSIKA----------KVTLQKPGESS---GEGLRPQMASS 1428
+ GST + I +S S VT G SS EG +++
Sbjct: 2864 ASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTP 2923
Query: 1429 KNYGSPLIS---GSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDG 1485
+PL S + P + + S +P T + + +E+ SS + P S G
Sbjct: 2924 SEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPG 2983
Query: 1486 IRPLP 1490
R P
Sbjct: 2984 ERRTP 2988
Score = 65.1 bits (157), Expect = 5e-10
Identities = 216/1010 (21%), Positives = 379/1010 (37%), Gaps = 120/1010 (11%)
Query: 522 TPALSLIAETVEDM---VKKNLPPASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNM 578
T A+S ++ T D V + SSP TT GT+ PT+T PG T L +M
Sbjct: 879 TSAISTLSTTPVDTSTPVTNSTEARSSP----TTSE----GTSMPTST-PGEGSTPLTSM 929
Query: 579 SMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGN 638
S S + +S P+ TS T + SSPT T P S+ +
Sbjct: 930 PDSTTPVVSS-----EARTLSATPVDTSTPVTTSTEAT---SSPTTAEGTSIPTSTPSEG 981
Query: 639 TK---NHPMLMNLLKDNPAQDFST--LYGSSPLERQN-SSSGSPRMEICSGSNKTKKKKS 692
T + P+ L+ ++ A ST + ++PL +SS P E S T + S
Sbjct: 982 TTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGS 1041
Query: 693 S---RLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAP----SQC 745
+ R+P + + L + D+ P+ + + + T T P S+
Sbjct: 1042 TPLTRMPVSTTMVASSET--STLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEG 1099
Query: 746 STPPTTYPQPVPHPQPSIQRMVRLSSSDSIG--PDVTDILSDIAEEASKLPSTSDDC--- 800
STP T+ P R+V S + ++ P T I + EAS P+T++
Sbjct: 1100 STPLTSVPVST--------RLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP 1151
Query: 801 ---PAIGT-PLRD---------SSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAG 847
P+ GT PL SS + +T DS + E P A+
Sbjct: 1152 TSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPT---AEVTS 1208
Query: 848 SPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLG 907
P+S + + S S D S+ + + + A T
Sbjct: 1209 MPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGT-S 1267
Query: 908 VPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEK 967
+P T +G+ ++ S V + L+ ++GP++T+ ++
Sbjct: 1268 LPT------STTSEGSTLLTSIPVSTTLVTSPEAST--LLTTPVDTKGPVVTSNEVSSSP 1319
Query: 968 TQKRVKEGNGTSNSTLSG--PGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHS 1025
T EG ST S L S P + S+ P + +P +
Sbjct: 1320 TPA---EGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTP------VDNSTPV-T 1369
Query: 1026 SSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTS 1085
+S + PT++ G+ P S P T P+ IP T V SS + S
Sbjct: 1370 TSTEACSSPTTSEGTSMPNS------NPSEGTTPL----TSIPVSTTPV--VSSEASTLS 1417
Query: 1086 SGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKN 1145
+ V +S + + ++SS ++A S+ SEG + K S+ S +S++
Sbjct: 1418 ATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLK---SIPVSNTPVANSEAST 1474
Query: 1146 SSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKL 1205
S + S +T S+ SS+ +G ++ PS ++ S P +
Sbjct: 1475 LSTTPVDSNSPVVT----STAVSSSPTPAEGTSIAISTPSEGSTALT---SIPVSTTTVA 1527
Query: 1206 ASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNS 1265
+S + + TP + +P+++ S S T+ + M++S+ S GS + P S
Sbjct: 1528 SSEINSLSTTP--AVTSTPVTTYSQASSSPTTADGTSMQTST--YSEGSTPLTSLPVSTM 1583
Query: 1266 CTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPL 1325
SS + + S + + S S++ S + + S+T ++TS P P+
Sbjct: 1584 LVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPV 1643
Query: 1326 DGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVST-SGSSVDSSKKTSESKNV 1384
ST S++ S+ ++ E ++ ST + + T + V
Sbjct: 1644 -ASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPV 1702
Query: 1385 GSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLIS---GSTP 1441
S+ ++ + + D +P + P S G + P S+ +PL S +TP
Sbjct: 1703 ASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSM-PNSTPSEG-TTPLTSIPVSTTP 1760
Query: 1442 KHERGSPSHSKSP--AYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPL 1489
+ + S +P TP +E+ S + AE + + + +G+ PL
Sbjct: 1761 VLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPL 1810
Score = 63.9 bits (154), Expect = 1e-09
Identities = 120/508 (23%), Positives = 200/508 (39%), Gaps = 47/508 (9%)
Query: 978 TSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTST 1037
TS++T G + + TP + P +A +P SN P T TST
Sbjct: 3202 TSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTP--VDSNTPLT--TST 3257
Query: 1038 GGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSH 1097
S SP +A + P + +T +P T V SS + S+ +S +
Sbjct: 3258 EASSSPPTAEGTSMPTSTPSEGSTPLT-SMPVSTTTVA--SSETSTLSTTPADTSTPVTT 3314
Query: 1098 HSHSSSSSSSASTSGKMKSSKSEGS----SSSKLSSSMYSSQGSSGSSQSKNSS---QSG 1150
+S +SSS A + S+ SEGS + S ++ + SS+ S+ S+ ++S +
Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTS 3374
Query: 1151 GKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISP---SHSRPPGGSDKLAS 1207
+ SP T G S +SS +G P + P +S + S P S+ L +
Sbjct: 3375 TEASLSPTTAEGTSIPTSSPS---EGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVT 3431
Query: 1208 PMKPVPGTPPSSKAKS-PISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPP--SSN 1264
+P ++ S P S+ S GS T S S++ + SS + + T P +S
Sbjct: 3432 TSTEASSSPTIAEGTSLPTSTTSEGS----TPLSIMPLSTTPVASSEASTLSTTPVDTST 3487
Query: 1265 SCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDP 1324
T SS + SS ++ +S + +G +P N S T V + T+ P
Sbjct: 3488 PVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTT------P 3541
Query: 1325 LDGQMGVSTNS--SSHP---------MSSKHNMSGGEFQGKREKSDKDKSKVST-SGSSV 1372
+D V+++S SS P MS+ S + S+ ST S SV
Sbjct: 3542 VDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSV 3601
Query: 1373 DSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASS--KN 1430
D S + S ST +I+ + +T+ +S AS+ +
Sbjct: 3602 DRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVD 3661
Query: 1431 YGSPLISGSTPKHERGSPSHSKSPAYTP 1458
+P+I+ + +P + P +TP
Sbjct: 3662 TSTPVITSTQVSSSPVTPEGTTMPIWTP 3689
Score = 63.5 bits (153), Expect = 2e-09
Identities = 202/938 (21%), Positives = 324/938 (34%), Gaps = 143/938 (15%)
Query: 563 PTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGSTIGSSP 622
PT+T P T L +MS+S S + S +S P+ TS T + S+ SS
Sbjct: 502 PTST-PSEGSTPLTSMSVSTMPVASS-----EASTLSTTPVDTSTPVTTSSEASS--SST 553
Query: 623 TPPHHTPPPVSSMAGNTK--NHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEI 680
TP + P + G+T N P+ L+ + A ST S SS S
Sbjct: 554 TPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTT 613
Query: 681 CSGSNKTKKKKSSR----LPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTP 736
G++ S R L + VDS P+ + T
Sbjct: 614 AEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTA 673
Query: 737 HITPAPSQC----STPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASK 792
T P+ STP T+ P S + + D+ P T + EAS
Sbjct: 674 EGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTT------STEASS 727
Query: 793 LPSTSDDC-----------------PAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPY 835
P+T+D P T L S +S S + L S T+ +
Sbjct: 728 SPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCS 787
Query: 836 TDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDF 895
+ + +PS SP V P + S S D +S + +
Sbjct: 788 PTTTEGTSMPISTPSEGSPL--LTSIPVSITP--VTSPEASTLSTTPVDSNSPVTTSTEV 843
Query: 896 KGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQG 955
+ A T +P T +G ++ S VA A++
Sbjct: 844 SSSPTPAEGT-SMPT------STYSEGRTPLTSMPVSTTLVATSAISTLST--------- 887
Query: 956 PLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKA 1015
T D T + T++ S P S PG+ S TP P +A
Sbjct: 888 ---TPVDTSTPVTNSTEARSSPTTSEGTSMP--TSTPGEGS-TPLTSMPDSTTPVVSSEA 941
Query: 1016 DTEGKSPSHSS-----SNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKG 1070
T +P +S S + PT+ G+ P S T P +TP +
Sbjct: 942 RTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEAS 1001
Query: 1071 TVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGS---SSSKL 1127
T+ S++ T+S + +SS +A + S+ SEGS + +
Sbjct: 1002 TLSTTPVDSNTPLTTS------------TEASSPPPTAEGTSMPTSTPSEGSTPLTRMPV 1049
Query: 1128 SSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLS 1187
S++M +S +S S + + S+P+T + +S SS+T + M S
Sbjct: 1050 STTMVASSETSTLSTTPADT-------STPVTTYSQASSSSTT------ADGTSMPTSTY 1096
Query: 1188 KPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSS 1247
+P S P ++S + TP + P+++ + S S +++ G +
Sbjct: 1097 SEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSI--PVTTSTEAS--SSPTTAEGTSIPT 1152
Query: 1248 GLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVI 1307
S G+ + P S + SS + + S + + S S++ SP TA +
Sbjct: 1153 SPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPP------TAEV 1206
Query: 1308 DKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVST 1367
+ TS PG ST +S P+ +H S D S T
Sbjct: 1207 TSMP----TSTPGER---------STPLTSMPV--RHTPVASSEASTLSTSPVDTSTPVT 1251
Query: 1368 SGSSVDSSKKTSESKNV-------GSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEG 1420
+ + SS T+E ++ GST + I +S SP +A L P ++ G
Sbjct: 1252 TSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP--EASTLLTTPVDTKG-- 1307
Query: 1421 LRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTP 1458
P + S++ SP TP P+ + S TP
Sbjct: 1308 --PVVTSNEVSSSP-----TPAEGTSMPTSTYSEGRTP 1338
Score = 62.4 bits (150), Expect = 3e-09
Identities = 227/1087 (20%), Positives = 391/1087 (35%), Gaps = 146/1087 (13%)
Query: 514 KAETIQADTPALSLIAETVEDMVKKNLPPASSPGYGMTTGNNPMSGTTTPT--------N 565
K+ + TP S+ A T++ + + ++P T +++PT N
Sbjct: 208 KSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSN 267
Query: 566 TFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGSTIGSSPTPP 625
+ P G T L M +S+ + + S +S P T++ IT S SSPT
Sbjct: 268 SAPSGGSTPLTRMPLSVM-----LVVSSEASTLSTTPAATNIPVITSTEAS---SSPTTA 319
Query: 626 HHTPPPVSSMA-GNT-------KNHPML---MNLLKDNPAQDFSTLYGSSP----LERQN 670
T P S+ G+T P+ M+ L P D STL +S L
Sbjct: 320 EGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPV-DTSTLVTTSTEPSSLPTTA 378
Query: 671 SSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTA 730
++ + GS S + + T ++ VDS+ + + +
Sbjct: 379 EATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTS-------TIPVDSKTFVTTASEAS 431
Query: 731 DTL----DTPHITPAPSQCSTPPTTYP---QPVPHPQPSIQRMVRLSSSDSIGPDVTDIL 783
+ DT T PS+ STP T+ P PV + S + S +
Sbjct: 432 SSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASS 491
Query: 784 SDIAEEASKLPSTSDDCPAIG-TPLRD---------SSSSGHSQSTLFDSDVFQTNNNE- 832
S E + +P+++ P+ G TPL SS + +T D+ T ++E
Sbjct: 492 SPPTAEVNSMPTST---PSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEA 548
Query: 833 --NPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSG 890
+ T I + S S TN + + + + + + SS++
Sbjct: 549 SSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEAS 608
Query: 891 DNDDFKGFASQALNTLGV--PMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLME 948
+ S +T + + T +++A T+ + + +
Sbjct: 609 SSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATS 668
Query: 949 HHSGSQGPLLTTGDLGKEKTQKRVKEGNGT-----SNSTLSGPGLD-SKPGKRSRTPSND 1002
+ ++G + T + T N T STLS +D S P S S+
Sbjct: 669 SSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSS 728
Query: 1003 GKSKDKPPKRKKADTEGKSP------------SHSSSNRPFTP-------PTSTGGSKSP 1043
+ D +EG +P S +S TP TST S SP
Sbjct: 729 PTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSP 788
Query: 1044 GSAGRSQTP---PGVATPPIPKITIQI-----PKGTVMVGKP-SSHSQYTSSGSVSSSGS 1094
+ + P P +P + I + I P+ + + P S+S T+S VSSS +
Sbjct: 789 TTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPT 848
Query: 1095 KSHHSHSSSSSSSAS----TSGKMKSSKSEGSSSSKLSSS--------MYSSQGSSGSSQ 1142
+ + +S+ S TS + ++ S+ S LS++ S++ S +
Sbjct: 849 PAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTT 908
Query: 1143 SKNSSQSGGKP--GSSPITKHGLSSGS--SSTKMKPQGKPSSLMNPSLSKPNISPSHSRP 1198
S+ +S P GS+P+T S+ SS P P + + S +
Sbjct: 909 SEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTA 968
Query: 1199 PGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQK 1258
G S ++P + GT P + +P+S + + T S++ + S++ L +S S
Sbjct: 969 EGTSIPTSTPSE---GTTPLT--STPVSHTLVANSEASTLSTTPVDSNTPLTTSTEAS-- 1021
Query: 1259 TPPSSNSCTASSSSFSSSGSS----MSSSQNQHGSSKGKSPSRNKKPSLTAVID-KLKHG 1313
+PP + T+ +S S GS+ M S SS+ + S + T V
Sbjct: 1022 SPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASS 1081
Query: 1314 VVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVD 1373
T+ G P ST +S P+S++ +S E S + V TS
Sbjct: 1082 SSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSS-------EASTLSTTPVDTSIPVTT 1134
Query: 1374 SSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRP-----QMASS 1428
S++ +S T + S+ S+ TL E++ P Q+A+S
Sbjct: 1135 STEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATS 1194
Query: 1429 KNYGSP-------LISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPS 1481
SP + STP ER +P S +TP S +S + S + S
Sbjct: 1195 TEASSPPPTAEVTSMPTSTP-GERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTS 1253
Query: 1482 SDDGIRP 1488
++ P
Sbjct: 1254 AETSSSP 1260
Score = 57.0 bits (136), Expect = 1e-07
Identities = 132/586 (22%), Positives = 224/586 (38%), Gaps = 89/586 (15%)
Query: 1017 TEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGK 1076
TE ++ S S+S+ P+ST + SP + + P ++TP + +I V
Sbjct: 113 TESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVP--MSTP--SEESISSTMAFVSTAP 168
Query: 1077 PSSHSQYTS-SGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGS--------SSSKL 1127
S YTS + V S + + +SSS ++ ++ KS+ SEGS S+ K+
Sbjct: 169 LPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKV 228
Query: 1128 SSS----------------MYSSQGSSGSSQSKNSSQSGGKP--GSSPITKHGLS----- 1164
+SS S+Q SS + ++ S S P GS+P+T+ LS
Sbjct: 229 ASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVV 288
Query: 1165 SGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSP 1224
S +ST P++ P ++ S S + G S +P T ++ +P
Sbjct: 289 SSEASTL---STTPAATNIPVITSTEASSSPTTAEGTS---------IP-TSTYTEGSTP 335
Query: 1225 ISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQ 1284
++S + TS S + S + + +S ++ T PSS TA ++S +S
Sbjct: 336 LTSTPASTMPVATSEMSTL-SITPVDTSTLVTTSTEPSSLPTTAEATSMLTS-------- 386
Query: 1285 NQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNS--SSHPMSS 1342
S+G +P N S V T P+D + V+T S SS P ++
Sbjct: 387 ---TLSEGSTPLTNMPVSTILVASSEASTTSTI------PVDSKTFVTTASEASSSPTTA 437
Query: 1343 KHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGV-AKIIISKHDGGS 1401
E + + S TS + +SE+ N+ +T V +K ++ S
Sbjct: 438 -------EDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEAS 490
Query: 1402 PSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNL 1461
S P + EG P + S P+ S E + S + TP
Sbjct: 491 SSPPTAEVNSMPTSTPSEGSTP-LTSMSVSTMPVASS-----EASTLSTTPVDTSTPVTT 544
Query: 1462 DSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRD 1521
SE+ S S+ E + + + +G PL E D +
Sbjct: 545 SSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTS 604
Query: 1522 KKKSHSIKPESWSKSPIS--SDQSLSMT----SNTILSADRPSRLS 1561
+ S S + P S S++ ++T S T++++ S LS
Sbjct: 605 SEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLS 650
Score = 55.5 bits (132), Expect = 4e-07
Identities = 172/847 (20%), Positives = 295/847 (34%), Gaps = 117/847 (13%)
Query: 717 VDSQNPIFDVNMTADTLDTPHITPAP----SQCSTPPTTYPQPVPHPQPSIQRMVRLSSS 772
VD P+ + + TP T P S+ STP T+ P S + + L++
Sbjct: 182 VDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASS-EAITLLTTP 240
Query: 773 DSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQST---------LFDS 823
I VT I+ +AS P+T++ G L +S+ SG S + S
Sbjct: 241 VEISTPVT-----ISAQASSSPTTAE-----GPSLSNSAPSGGSTPLTRMPLSVMLVVSS 290
Query: 824 DVFQTNNNENPYTDPADLIADAAGSPSSDS----PTNHFFHDGVDFNPDLLNSQSQSGFG 879
+ + P +A+ SP++ PT+ + L S S
Sbjct: 291 EASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTP-----LTSTPASTMP 345
Query: 880 EEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNG---ETKFKGNNQADTVDFSIISV 936
+ S+ S D + + +P T +G+ + S I V
Sbjct: 346 VATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILV 405
Query: 937 AGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRS 996
A + + S + +TT TS + L S P +
Sbjct: 406 ASSEASTTSTIPVDSKT---FVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTT 462
Query: 997 RTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVA 1056
S++ + P K + S +S+ P T ++ + +P T V+
Sbjct: 463 PVASSEASNLSTTPVDSKTQV---TTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVS 519
Query: 1057 TPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKS 1116
T P+ SS + S+ V +S + S +SSSS++ + S
Sbjct: 520 TMPVA----------------SSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTS 563
Query: 1117 SKSEGSS-------SSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSS 1169
+ SEGS+ S++L S +S S+ + S + + SS T G S +S+
Sbjct: 564 TPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTST 623
Query: 1170 TKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGS 1229
+ S ++ +L + + + S P S+ + + +++ S +S
Sbjct: 624 YSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTS-- 681
Query: 1230 GGSHMSGTSSSSGMKSSSGL--GSSGSLSQKTP-----PSSNSCTASSSSFSSSGSSMSS 1282
++ G++ + M ++ L S S TP P + S ASSS ++ G+SM +
Sbjct: 682 --TYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT 739
Query: 1283 SQNQHGS--------SKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQ---MGV 1331
S GS SK S T +D H + TS P + M +
Sbjct: 740 STPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTH-ITTSTEASCSPTTTEGTSMPI 798
Query: 1332 STNSSSHPMSSKHNMS----GGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE------- 1380
ST S P+ + +S + D + T+ + V SS +E
Sbjct: 799 STPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTS 858
Query: 1381 ----------SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESS---GEGLRPQMAS 1427
S V +T VA IS VT SS EG ++
Sbjct: 859 TYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST 918
Query: 1428 SKNYGSPLIS---GSTPKHERGSPSHSKSP--AYTPQNLDSESESGSSIAEKSYQNSPSS 1482
+PL S +TP + + S +P TP +E+ S + AE + + +
Sbjct: 919 PGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTP 978
Query: 1483 DDGIRPL 1489
+G PL
Sbjct: 979 SEGTTPL 985
Score = 52.4 bits (124), Expect = 3e-06
Identities = 182/833 (21%), Positives = 299/833 (35%), Gaps = 131/833 (15%)
Query: 505 PVTMRAIRRKAET-IQADTPALSLIAETVEDMVKKNLPPASSPGYGMTTGNNPMSGTTTP 563
PVT AI + T + TP V + + P +S G M T + P G+T
Sbjct: 3116 PVTSSAISTLSTTPVDTSTP--------VTTSTEAHSSPTTSEGTSMPT-STPSEGSTPL 3166
Query: 564 TNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGSTIGSSPT 623
T P++T+ +S ED S +S P+ TS T ST +S T
Sbjct: 3167 TYM----PVSTMLVVS------------SED-STLSATPVDTSTPVTT----STEATSST 3205
Query: 624 PPHHTPPPVSSMAGNTKNHPMLMNLLKDNP-AQDFSTLYGSSPLERQNSSSGSPRMEICS 682
T P S+ + P+ + + P A +++ ++P++ S +P
Sbjct: 3206 TAEGTSIPTSTPSEGMT--PLTSVPVSNTPVASSEASILSTTPVD-----SNTPLTTSTE 3258
Query: 683 GSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAP 742
S+ + + +P P + L SM V + T + +T ++ P
Sbjct: 3259 ASSSPPTAEGTSMPTSTPSEGSTP-----LTSMPVSTT--------TVASSETSTLSTTP 3305
Query: 743 SQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSD----IAEEASKLPSTSD 798
+ STP TTY Q P + + S+ +T++ ++ EAS L +T
Sbjct: 3306 ADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPV 3365
Query: 799 DCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSP---- 854
D TP+ S+ + S +T + + P + P++ A P S +P
Sbjct: 3366 D---TSTPVTTSTEASLSPTTAEGTSI--------PTSSPSEGTTPLASMPVSTTPVVSS 3414
Query: 855 -TNHFFHDGVDFNPDLLNSQSQSGF-----GEEYFDESSQSGDND------DFKGFASQA 902
N VD N + S S G ++ G AS
Sbjct: 3415 EVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSE 3474
Query: 903 LNTLGVPMLGGDNGETKFKGNNQADT---VDFSIISVAGKALAPADLMEHHSGSQGPLLT 959
+TL + T N + T V S AG+ P M P+ T
Sbjct: 3475 ASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNM--------PVST 3526
Query: 960 TGDLGKEKTQKRVKEGNG-----TSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKP--PKR 1012
T E + + +S+ S P R TPS S
Sbjct: 3527 TPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSST 3586
Query: 1013 KKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTV 1072
+E +PS S +R TST + +P TPP V T P+ + T+
Sbjct: 3587 YVTSSEASTPSTPSVDRSTPVTTSTQSNSTP-------TPPEVITLPMSTPSEVSTPLTI 3639
Query: 1073 MVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMY 1132
M P S T+S ++S +G+ S +S+ ST EG++ + S
Sbjct: 3640 M---PVS----TTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEG 3692
Query: 1133 SSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNIS 1192
S+ ++ + + S G S+P ++S +T + ++L + ++S +S
Sbjct: 3693 STPLTTMPVSTTRVTSSEGSTLSTPSV---VTSTPVTTSTEAISSSATLDSTTMS---VS 3746
Query: 1193 PSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSS 1252
G+ L S PV P SS P S + MS T++S G S + L +
Sbjct: 3747 MPMEISTLGTTILVS-TTPVTRFPESSTPSIP----SVYTSMSMTTASEGSSSPTTLEGT 3801
Query: 1253 GSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTA 1305
++ T +S T ++ S S MS S+ S+ P P LT+
Sbjct: 3802 TTMPMST--TSERSTLLTTVLISPISVMSPSE---ASTLSTPPGDTSTPLLTS 3849
Score = 46.2 bits (108), Expect = 2e-04
Identities = 151/763 (19%), Positives = 267/763 (34%), Gaps = 98/763 (12%)
Query: 559 GTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKV-SQNPILTS--------LLQ 609
GT+ PT+T G T L M +S S + V + P+ TS +
Sbjct: 3445 GTSLPTSTTSEGS-TPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAE 3503
Query: 610 ITGNGGSTIGSSPTP----PHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFS------- 658
+T ST G TP P T P SS A P+ N + +Q S
Sbjct: 3504 VTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQV 3563
Query: 659 -TLYGSSPLERQNS-----------------SSGSPRMEICSGSNKTKKKKSSRLPPE-- 698
T+ S+P E +S + +P ++ + + + S+ PPE
Sbjct: 3564 TTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVI 3623
Query: 699 KPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPA--PSQCSTPPTTYPQPV 756
T + L M V + + TA TL TP +Q S+ P T
Sbjct: 3624 TLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVT----- 3678
Query: 757 PHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHS 816
P M + S+ P T +S +S+ + S TP+ S+ + S
Sbjct: 3679 ----PEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISS 3734
Query: 817 QSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQS 876
+TL DS + P ++ S +P F P + S S +
Sbjct: 3735 SATL-DSTTMSVSM-------PMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMT 3786
Query: 877 GFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISV 936
E ++ G T +PM T + + TV S ISV
Sbjct: 3787 TASEGSSSPTTLEG--------------TTTMPM------STTSERSTLLTTVLISPISV 3826
Query: 937 AGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRS 996
+ A + L + PLLT+ G V + S S P L + +
Sbjct: 3827 MSPSEA-STLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTP-LTTLLVSTT 3884
Query: 997 RTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVA 1056
S G S P + T +PS +++ P P +T T +
Sbjct: 3885 LPTSFPGASIASTPPLDTSTTF--TPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIP 3942
Query: 1057 TPPIPKITIQI-PKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMK 1115
+ P+ T + P T V P S ++ S SSS + + S + ++ A T+
Sbjct: 3943 STPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPL 4002
Query: 1116 SSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQ 1175
+ + ++ S ++ S+ + + ++ + + P+T SS
Sbjct: 4003 TYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESS---------- 4052
Query: 1176 GKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMS 1235
+PS++ + ++ P P+HS P + ++ + P T +++ K P + + ++
Sbjct: 4053 -RPSTITSHTI-PPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTK-PSTRTTSFPTVT 4109
Query: 1236 GTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGS 1278
T+ + S S+ ++ + T + C ++S + G+
Sbjct: 4110 TTAVPTNTTIKSNPTSTPTVPRTTTCFGDGCQNTASRCKNGGT 4152
Score = 40.4 bits (93), Expect = 0.014
Identities = 103/452 (22%), Positives = 176/452 (38%), Gaps = 68/452 (15%)
Query: 1067 IPKGTVMVGKPSSHSQYTSSGSVSSS--GSKSHHSHSSSSSSSASTSGKMKSSKSEGSSS 1124
I +G V+ + SQ+ +GS +++ G+ S + S ST+ +M S +S +S
Sbjct: 42 ISQGDVLNRQCQQLSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSD 101
Query: 1125 SK-LSSSMYSSQGSSGSSQSKNSSQ----SGGKPGSSPITKHG----LSSGSSSTKMKPQ 1175
+ +SS+ + S +S+S + S S + SSP T G +S+ S +
Sbjct: 102 TPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTM 161
Query: 1176 GKPSSLMNPSL---SKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGS 1232
S+ PS + S P S + +S P TP S+ P S+ S GS
Sbjct: 162 AFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSS----PTTPESTTI--PKSTNSEGS 215
Query: 1233 HMSGTSSSSGMK--SSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1290
+ +S MK SS + + + + P + S ASSS ++ G S+S+S S
Sbjct: 216 TPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNS----APS 271
Query: 1291 KGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGE 1350
G +P S+ V+ + T+ P+ ST +SS P +++
Sbjct: 272 GGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVI----TSTEASSSPTTAE------- 320
Query: 1351 FQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTL 1410
G+S+ +S T S + ST + + ++ + + SI T
Sbjct: 321 ------------------GTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTS 362
Query: 1411 QKPGESSGEGLRPQMASSKN-YGSPLISGSTP------------KHERGSPSHSKSPAYT 1457
S+ P A + + S L GSTP E + S + T
Sbjct: 363 TLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKT 422
Query: 1458 PQNLDSESESGSSIAEKSYQNSPSSDDGIRPL 1489
SE+ S + AE + + + +G PL
Sbjct: 423 FVTTASEASSSPTTAEDTSIATSTPSEGSTPL 454
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 70.1 bits (170), Expect = 2e-11
Identities = 127/591 (21%), Positives = 218/591 (36%), Gaps = 82/591 (13%)
Query: 992 PGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTS-TGGSKSPGSAGRSQ 1050
PGK + + GK D +++D++G++P+ +S + PP ++SP AG +
Sbjct: 839 PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP--AGPAA 896
Query: 1051 TPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAST 1110
TP P+ S ++ +SS S + + ++ T
Sbjct: 897 TPAQAQAASTPR----------KARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVT 946
Query: 1111 SGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGK-PGSSPITKHGLS----S 1165
+ +S + SSS SS+ S G Q ++Q K P S P+T+ L
Sbjct: 947 MPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQK 1006
Query: 1166 GSSSTKMKPQGKPSSLMNPSLSK-PNISP-SHSRPPGGSDKLASPMKP----VPGTPPSS 1219
S + + +PSS ++ ++ P SP S S G++KL P P P SS
Sbjct: 1007 ASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESS 1066
Query: 1220 KAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSS 1279
S S GS G + G S+ +L TP + + +++ SS
Sbjct: 1067 DDSEDSSDSSSGSEEDG-------EGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDV 1119
Query: 1280 MSSSQNQHGS--SKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSS 1337
++ SQ+ + G +P+ ++ T +D V+S +D DG+ ++
Sbjct: 1120 VAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPS--VSSTLAAKDDPDGKQEAKPQQAA 1177
Query: 1338 HPMSSK---HNMSGGEFQGKREKSDKDKSKVSTSGSSVDSS------------------- 1375
+S K + G K K K S ++ S+
Sbjct: 1178 GMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQA 1237
Query: 1376 --------------KKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEG- 1420
KK ++ S + K G P+ + + +K +GEG
Sbjct: 1238 SVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGG 1297
Query: 1421 ---LRPQMASSKNYGSPL---ISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEK 1474
+ P+ S+ + G SG K ++G S A + E + G E
Sbjct: 1298 EASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGA--KDEPEEELQKGMGTVEG 1354
Query: 1475 SYQNSPSSDDGIRPLPEYSTEKHKKHKKEK-KKVKDKDRDRDRDKDRDKKK 1524
Q++P S + + +K KK KK+K KK KD + K + KKK
Sbjct: 1355 GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKK 1405
Score = 65.5 bits (158), Expect = 4e-10
Identities = 207/1020 (20%), Positives = 349/1020 (34%), Gaps = 171/1020 (16%)
Query: 543 ASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFS-KVSQN 601
AS+P G P G T P G + + + + K +S E+ S +
Sbjct: 226 ASAPAKG-----TPGKGATPA----PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEET 276
Query: 602 PILTSLLQITGNGG-STIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTL 660
P +LLQ +G S +G++ P +P ++ A K P + +D +
Sbjct: 277 PAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS 336
Query: 661 YGSSPLERQNSSSGSPR---MEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDV 717
S E + + P ++ + S K+ P P+ Q ++ +
Sbjct: 337 SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE 396
Query: 718 DSQNPIFDVNMTADTL------------DTPHITPAPSQCSTPPTTYPQPVPHPQPSIQR 765
DS++ + + + L +P + PA + P PVP +
Sbjct: 397 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPG-----K 451
Query: 766 MVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDV 825
+ + S +G D S +EE+S S+ + P P ++ S ++
Sbjct: 452 VGPATPSAQVGKWEEDSESS-SEESSD--SSDGEVPTAVAPAQEKSLG----------NI 498
Query: 826 FQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDE 885
Q +P P A ++ P + NS+S +E
Sbjct: 499 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMD--------------NSESS--------EE 536
Query: 886 SSQSGDNDDFKGF--ASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISV--AGKAL 941
SS S D+++ A+QA L +P +T + + V + AG A
Sbjct: 537 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 596
Query: 942 APADLMEHHSG-SQGPLLTTG-----DLGKEKTQKRVKEGNGTSNSTLSGPGLDSKP--- 992
+PA +G +Q P + D +EKT V G S G GL K
Sbjct: 597 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKS----VGKGLQVKAASV 652
Query: 993 --------GKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTP----------- 1033
G P G + + K+ D+E S +P
Sbjct: 653 PVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQ 712
Query: 1034 ----------PTSTGGSKSPG-----SAGRSQTPPGVATPPIPK-----ITIQIPKGTVM 1073
P++ G +PG +A Q P PP+ + + P
Sbjct: 713 AKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPS 772
Query: 1074 VGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYS 1133
VGK + + +G SGS S S A T ++K S + L+ + S
Sbjct: 773 VGKAVATAAQAQTGPEEDSGSSE---EESDSEEEAETLAQVKPSGKTHQIRAALAPAKES 829
Query: 1134 SQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGK-PSSLMNPSLSKPN-I 1191
+ + + + S + G SGSSS + G+ P+++ + + KP I
Sbjct: 830 PRKGAAPTPPGKTGPSAAQAGKQD------DSGSSSEESDSDGEAPAAVTSAQVIKPPLI 883
Query: 1192 SPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGS 1251
+R P G P S+ K+ S + S S + + ++ L
Sbjct: 884 FVDPNRSPAG-----PAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTP 938
Query: 1252 SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHG-SSKGKSPSRNKK-----PSLTA 1305
+ T P+++ A +S + + SS SS+ G +G + +KK P A
Sbjct: 939 GIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQA 998
Query: 1306 VIDKLKHGVVTSGP--GGEDPLDG-QMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDK 1362
+ L + P P G V T ++ P S+ G K K K
Sbjct: 999 ALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKG------TNKLRKPK 1052
Query: 1363 SKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSP-SIKAKVTLQKPGESSGEGL 1421
+ S SE + S+G S+ DG P K+ TL P S E L
Sbjct: 1053 LPEVQQATKAPESSDDSEDSSDSSSG------SEEDGEGPQGAKSAHTLVGPTPSRTETL 1106
Query: 1422 RPQMASSKNY------GSPLISG-STPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEK 1474
+ A+ + L+SG TP +P++S++ TP+ LDS S++A K
Sbjct: 1107 VEETAAESSEDDVVAPSQSLLSGYMTPGL---TPANSQASKATPK-LDSSPSVSSTLAAK 1162
Score = 49.7 bits (117), Expect = 2e-05
Identities = 86/407 (21%), Positives = 134/407 (32%), Gaps = 67/407 (16%)
Query: 1101 SSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITK 1160
S+S SS + +++K+ +S SS + + SS ++K ++ GK G+S
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS---- 138
Query: 1161 HGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSK 1220
M ++ N K SP S P + L S + P
Sbjct: 139 -----------MPHPATGKTVANLLSGK---SPRKSAEPSANTTLVSETEEEGSVPAFGA 184
Query: 1221 AKSP--ISSGSGGSHMSGTSSSSG----------------MKSSSGLGSSGSLSQKTPPS 1262
A P +S+G S TSSSS S+ G+ G + PP
Sbjct: 185 AAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPG 244
Query: 1263 SNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGE 1322
AS + SS + S+ ++P+ K K S P E
Sbjct: 245 KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA-KALLQAKASGKTSQVGAASAPAKE 303
Query: 1323 DPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESK 1382
P G + ++ GKRE+ + S+ S S + K S
Sbjct: 304 SPRKGAAPAPPGKTGPAVAKAQ-------AGKREEDSQSSSEESDSEEEAPAQAKPS--- 353
Query: 1383 NVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPK 1442
G +P ++A K ES +G P A + G K
Sbjct: 354 ----------------GKAPQVRAASAPAK--ESPRKGAAP--APPRKTGPAAAQVQVGK 393
Query: 1443 HERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPL 1489
E S S S+ + L + + + KS Q P+S G+ PL
Sbjct: 394 QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 440
Score = 45.4 bits (106), Expect = 4e-04
Identities = 98/506 (19%), Positives = 166/506 (32%), Gaps = 87/506 (17%)
Query: 987 GLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSA 1046
G +KPG S + D S+D + D E K+ R + P G+
Sbjct: 183 GAAAKPGMVSAGQA-DSSSEDTSSSSDETDVEVKASEKILQVRAASAPAK-------GTP 234
Query: 1047 GRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSS 1106
G+ TP PP GK + + T +G S+S SS S
Sbjct: 235 GKGATP----APP---------------GKAGAVASQTKAGKPEED-SESSSEESSDSEE 274
Query: 1107 SASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSG 1166
+ + +K+ G +S ++S + + + ++G + K S
Sbjct: 275 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 334
Query: 1167 SSSTKMKPQGKPSSLMNPSLSKPNI----SPSHSRPPGGSDKLASPMKPVPGTPPSSKAK 1222
SSS + + + + PS P + +P+ P G+ A P K P K
Sbjct: 335 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP-APPRKTGPAAAQVQVGK 393
Query: 1223 SPISSGSGGSHMS-----------------GTSSSSGMKSSSGLGSSGSLSQKTPPSS-N 1264
S S G S S+ G+G G + PP
Sbjct: 394 QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVG 453
Query: 1265 SCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDP 1324
T S+ S SSS+ SS G+ P+ P+ + + TS P P
Sbjct: 454 PATPSAQVGKWEEDSESSSEESSDSSDGEVPTA-VAPAQEKSLGNILQAKPTSSPAKGPP 512
Query: 1325 LDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSES--- 1381
+ PM + + + + +D +++ + + + + K ++
Sbjct: 513 QKAGPVAVQVKAEKPMDNSESS-----EESSDSADSEEAPAAMTAAQAKPALKIPQTKAC 567
Query: 1382 -KNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGST 1440
K +T AK+ +V Q P ++ A+S SP ++G T
Sbjct: 568 PKKTNTTASAKV-----------APVRVGTQAPRKAG-------TATSPAGSSPAVAGGT 609
Query: 1441 PKHERGSPSHSKSPAYTPQNLDSESE 1466
+ S S +S DSE E
Sbjct: 610 QRPAEDSSSSEES--------DSEEE 627
>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
Length = 587
Score = 69.7 bits (169), Expect = 2e-11
Identities = 103/430 (23%), Positives = 173/430 (40%), Gaps = 82/430 (19%)
Query: 1083 YTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQ 1142
+ S + S G +S SHS ST+ + S+ S S+ + +S +SS GS+ ++
Sbjct: 3 FPESDTTSGRGEESTTSHS-------STTHTISSAPSTTSALVEEPTSYHSSPGSTATTH 55
Query: 1143 SKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNIS--------PS 1194
+SS + G+ S H + + + + S L+ S + P S P
Sbjct: 56 FPDSSTTSGRSEES-TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 114
Query: 1195 HSRPPGGSDKL----ASPMKPVPGTPPSSKAKSPISSGSGGSH----MSGTSSSSGMKSS 1246
+ PG S+K +SP P P+S S +S S SH + T++ ++
Sbjct: 115 STTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTT 174
Query: 1247 SGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAV 1306
GL + S +P S+++ T +S ++SG S S+ + SS G + + S TA+
Sbjct: 175 PGLSRHSTTSHSSPGSTDT-TLLPASTTTSGPSQESTTSH--SSPGSTDTALSPGSTTAL 231
Query: 1307 IDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVS 1366
+ S PG ST+++ P S +
Sbjct: 232 SFGQESTTFHSSPG-----------STHTTLFPDS------------------------T 256
Query: 1367 TSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMA 1426
TS V++S + STG + +S SP ++ GES+ P A
Sbjct: 257 TSSGIVEASTRVH-----SSTGSPRTTLSPASSTSPGLQ--------GESTAFQTHP--A 301
Query: 1427 SSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKS--YQNSPSSDD 1484
S+ SP + + P E S ++ +SP TP S + S +EKS + +SP +
Sbjct: 302 STHTTPSPPSTATAPVEE--STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA-S 358
Query: 1485 GIRPLPEYST 1494
G P +ST
Sbjct: 359 GTTPSSAHST 368
Score = 65.1 bits (157), Expect = 5e-10
Identities = 128/575 (22%), Positives = 213/575 (37%), Gaps = 78/575 (13%)
Query: 806 PLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDF 865
P D++S +ST S T ++ A + S + PT++ G
Sbjct: 4 PESDTTSGRGEESTTSHSSTTHTISS-----------APSTTSALVEEPTSYHSSPGSTA 52
Query: 866 NPDLLNSQSQSGFGEEYFDESSQSGDNDDFKG-FASQALNTLGV--------PMLGGDNG 916
+S + SG EE S+ S + D G A +T V P+ G
Sbjct: 53 TTHFPDSSTTSGRSEE----STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 108
Query: 917 ETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGN 976
T G+ + + +PA + S T+ + +E T + G
Sbjct: 109 TTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAS------TTSSGVSEESTTSHSRPG- 161
Query: 977 GTSNSTLSGPGLDSKPG--KRSRTPSNDGKSKDKPPKRKKADTEGKSP----SHSS---S 1027
S T + P + PG + S T + S D T G S SHSS +
Sbjct: 162 --STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 219
Query: 1028 NRPFTPPTSTGGS---------KSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPS 1078
+ +P ++T S SPGS + P + I + + ++ T
Sbjct: 220 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 279
Query: 1079 SHSQYTSSGSVSSSGSKSHH---SHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQ 1135
S + TS G S + H +H++ S S +T+ +S+ S S ++ +S
Sbjct: 280 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 339
Query: 1136 GSSGSSQSK-----NSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPN 1190
+SG S+ + SG P S+ T G+S SS++ +P ++ S +
Sbjct: 340 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSG 399
Query: 1191 IS--PSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSG 1248
+S P+ S GS + P +PP + A S + S S T ++ SS+
Sbjct: 400 LSQEPTTSHSSQGSTEATLDTTP---SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTT 456
Query: 1249 LG-SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVI 1307
LG S S + + P S TA S +++G S S+ S +SP P+ T
Sbjct: 457 LGRSEESTTVHSSPGSTETTALPGSTTTAGLSEKSTTFY---SSPRSPDTTLSPAST--- 510
Query: 1308 DKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSS 1342
+SG E ST++++ P S+
Sbjct: 511 -------TSSGVSEESTTSHSRPGSTHTTAFPGST 538
>gi|89026265 PREDICTED: mucin 12 [Homo sapiens]
Length = 978
Score = 69.7 bits (169), Expect = 2e-11
Identities = 109/465 (23%), Positives = 188/465 (40%), Gaps = 45/465 (9%)
Query: 1034 PTSTGGSKS---PGS---AGRSQTPPGVATPPIPKITIQIPKGTVMVG----KPSSHSQY 1083
P S+G +++ PGS AG S+ + P T P T G +SHS+
Sbjct: 3 PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 62
Query: 1084 TSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKL----SSSMYSSQGSSG 1139
S+ + + GS + S S++S S+ G ++ S GS+++ S++ +S GS+
Sbjct: 63 GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTE 122
Query: 1140 SSQ-SKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSL--SKPNISPSHS 1196
++ N++ SG S+P+ S+GS T + P G + + S PN +
Sbjct: 123 TTLLPDNTTASGLLEASTPVHS---STGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP 179
Query: 1197 RPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS 1256
PP + G+P S+ P + S S G S S SS + ++ + S
Sbjct: 180 APPTTTSAFVELSTTSHGSPSST----PTTHFSASSTTLGRSEESTTVHSSPVATATTPS 235
Query: 1257 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKS-PSRNKKPSLTAVIDKLKHGVV 1315
+S S++ SS GS+ + + ++ G+S SR S T I
Sbjct: 236 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTI-------- 287
Query: 1316 TSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSS 1375
S P + S +SS +++ H G+ E+S S T+G + +
Sbjct: 288 -SSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPA 346
Query: 1376 KKTSESKNVGST------GVAKIIISKHDGGSPSIKAKVT-LQKPGESSGEGLRP-QMAS 1427
T+ + ST G + ++ +P + AK T L S + L P M S
Sbjct: 347 HFTTSGRIAESTTFYISPGSMETTLAS-TTTTPGLSAKSTILYSSSRSPDQTLSPASMTS 405
Query: 1428 SKNYGSP--LISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSS 1470
S G P L S + H P+ + + + ++ S+ GS+
Sbjct: 406 SSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGST 450
Score = 67.8 bits (164), Expect = 8e-11
Identities = 134/599 (22%), Positives = 212/599 (35%), Gaps = 88/599 (14%)
Query: 916 GETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEG 975
G T G +Q T S L+P + S GP TT G T+ +
Sbjct: 72 GSTTMPGVSQESTASHSSPGSTDTTLSPGSTT---ASSLGPESTTFHSGPGSTETTLLPD 128
Query: 976 NGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPT 1035
N T++ L E +P HSS+ P T +
Sbjct: 129 NTTASGLL----------------------------------EASTPVHSSTGSPHTTLS 154
Query: 1036 STGGSKSPGSAGRSQT-PPGVATPPIPKITIQ--IPKGTVMVGKPSSHSQYTSSGSVSSS 1092
G + G + Q+ P T P P T + T G PSS T+ S SS+
Sbjct: 155 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTP--TTHFSASST 212
Query: 1093 GSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGK 1152
++ SS +T+ ++S S + S++ +SS GS+ + SS + G+
Sbjct: 213 TLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGR 272
Query: 1153 PGSS----PITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKL--- 1205
S T H +SS S+T + S +P P S G S++
Sbjct: 273 SEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTAS 332
Query: 1206 -ASP----MKPVPG--TPPSSKAKSP---ISSGSGGSHMSGTSSSSGMKSSSGLGSSGSL 1255
+SP + P+P T A+S IS GS + ++ T+++ G+ + S + S S
Sbjct: 333 HSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTTTTPGLSAKSTILYSSSR 392
Query: 1256 SQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVV 1315
S P AS +S S SG S + P+ L+ +
Sbjct: 393 S----PDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQ-----ESTTF 443
Query: 1316 TSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQ----------GKREKSDKDKSKV 1365
S PG + ++T+S + ++ H+ G G E+S S
Sbjct: 444 HSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSP 503
Query: 1366 STSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQM 1425
++ ++ S T + ST H + A +T G+ E
Sbjct: 504 GSTETTAFSHSNTMSIHSQQSTPFPDSPGFTH----TVLPATLTTTDIGQ---ESTAFHS 556
Query: 1426 ASSKNYGSPLISGSTPKHERGSPSH---SKSPAYTPQNLDSESESGSSIAEKSYQNSPS 1481
+S +PL + ST G P+ S SP YT S S SG + ++ SPS
Sbjct: 557 SSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPS 615
Score = 52.0 bits (123), Expect = 5e-06
Identities = 93/374 (24%), Positives = 149/374 (39%), Gaps = 51/374 (13%)
Query: 1143 SKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISP----SHSRP 1198
S S+++ PGS+ T GLS S++ P+ ++L S + +S SHSRP
Sbjct: 5 SSGSTETTALPGST--TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 62
Query: 1199 PGGSDKLASP-MKPVPGTPPSSKAK--SPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSL 1255
G + A P +PG S A SP S+ + S S T+SS G +S++ GS
Sbjct: 63 -GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGST 121
Query: 1256 SQKTPPSSNSCT----ASSSSFSSSGS-----SMSSSQNQHGSSKGKSPSRNKKPSLTAV 1306
P + + + AS+ SS+GS S + S + G S N K +
Sbjct: 122 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTT--- 178
Query: 1307 IDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSK--HNMSGGEFQGKREKSDKDKSK 1364
P + +ST S P S+ H + G+ E+S
Sbjct: 179 ------------PAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES------ 220
Query: 1365 VSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQ 1424
+T SS ++ T ++G+ + + H SP + T+ P S+ G +
Sbjct: 221 -TTVHSSPVATATTPSPARSTTSGLVEESTAYHS--SPG--STQTMHFPESSTASGRSEE 275
Query: 1425 MASSKNYGSPLISG---STPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPS 1481
+S + + IS +T S+ SP ES + S +E+S + S
Sbjct: 276 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS 335
Query: 1482 SD-DGIRPLPEYST 1494
D +GI PLP + T
Sbjct: 336 PDTNGITPLPAHFT 349
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 69.7 bits (169), Expect = 2e-11
Identities = 121/587 (20%), Positives = 221/587 (37%), Gaps = 112/587 (19%)
Query: 992 PGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPP--------TSTGGSKSP 1043
PGK + + GK D +++D++G++P+ +S + PP + G + +P
Sbjct: 916 PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATP 975
Query: 1044 GSAGRSQTPPGVATPP---------------IPKITIQIPK-GTVMVGKPSSHSQYTSSG 1087
A + TP IP P T +V P++H +
Sbjct: 976 AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKA 1035
Query: 1088 SVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK--N 1145
S++ + S S S + ++ S+ ++S S+S+ ++G++ + K
Sbjct: 1036 SMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSV-QAKGTNKLRKPKLPE 1094
Query: 1146 SSQSGGKPGSSPITKHG--LSSGSSSTKMKPQGKPS--SLMNPSLSKPNISPSHSRPPGG 1201
Q+ P SS ++ SSGS PQG S +L+ P+ S+ +
Sbjct: 1095 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESS 1154
Query: 1202 SDKLASPMKPV------PG-TPPSSKAKSPI----SSGSGGSHMSGTSSSSGMKSSSGLG 1250
D + +P + + PG TP +S+A SS S S ++ G + +
Sbjct: 1155 EDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQ 1214
Query: 1251 SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL 1310
++G LS KT G +S G +P +++KP
Sbjct: 1215 AAGMLSPKT----------------GGKEAAS---------GTTPQKSRKPK-------- 1241
Query: 1311 KHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGK-----REKSDKDKSKV 1365
G +P + + +N + + ++ + Q E ++++ KV
Sbjct: 1242 --------KGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKV 1293
Query: 1366 STSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEG----L 1421
++ +SS+K ES+ K G P+ + + +K +GEG +
Sbjct: 1294 --VDTTKESSRKGWESRK-----------RKLSGDQPAARTPRSKKKKKLGAGEGGEASV 1340
Query: 1422 RPQMASSKNYGS---PLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQN 1478
P+ S+ + G SG K ++G S A + E + G E Q+
Sbjct: 1341 SPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGA--KDEPEEELQKGMGTVEGGDQS 1397
Query: 1479 SPSSDDGIRPLPEYSTEKHKKHKKEK-KKVKDKDRDRDRDKDRDKKK 1524
+P S + + +K KK KK+K KK KD + K + KKK
Sbjct: 1398 NPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKK 1444
Score = 54.7 bits (130), Expect = 7e-07
Identities = 138/721 (19%), Positives = 242/721 (33%), Gaps = 95/721 (13%)
Query: 872 SQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDF 931
SQ+++G EE + SS+ + + + A++AL + +G+T G A +
Sbjct: 328 SQTKAGKPEEDSESSSEESSDSEEETPAAKAL------LQAKASGKTSQVGAASAPAKES 381
Query: 932 SIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSK 991
K APA G GP + GK + + + S+S P
Sbjct: 382 P-----RKGAAPAP-----PGKTGPAVAKAQAGKREEDSQ--SSSEESDSEEEAPAQAKP 429
Query: 992 PGKRSRTPSNDGKSKDKP-------PKRK-----------KADTEGKSPSHSS-SNRPFT 1032
GK + + +K+ P P RK K + + +S S S S+R
Sbjct: 430 SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREAL 489
Query: 1033 PPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSS 1092
+ K G + + + + P+ K +P G V PS +
Sbjct: 490 AAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS-----------AQV 538
Query: 1093 GSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGK 1152
G S SSS SS S+ G++ ++ + S L + + + K
Sbjct: 539 GKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS-LGNILQA------------------K 579
Query: 1153 PGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPV 1212
P SSP +G + ++K + KP S + + S P + A P +
Sbjct: 580 PTSSPAKGPPQKAGPVAVQVKAE-KPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKI 638
Query: 1213 PGT--------PPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSN 1264
P T +S +P+ G+ +GT++S S + G +Q+ S+
Sbjct: 639 PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGG----TQRPAEDSS 694
Query: 1265 SCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDP 1324
S S S +G +++ G +K K + V L G PG P
Sbjct: 695 SSEESDSEEEKTGLAVTV-----GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP 749
Query: 1325 LDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNV 1384
Q+ S S S E K K + + ++ +++ S +
Sbjct: 750 TVTQVKAEKQEDS---ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
Query: 1385 GSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASS--KNYGSPLISGSTPK 1442
+ G ++ SPS K K ++ P S+ P S K + + + P+
Sbjct: 807 SAPGKVVTAAAQAKQRSPS-KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 865
Query: 1443 HERGSPSHSKSPAYTPQNLDSESESGSS----IAEKSYQNSPSSDDGIRPLPEYSTEKHK 1498
+ GS + L SG + A + SP P + +
Sbjct: 866 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 925
Query: 1499 KHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPS 1558
K++ ++ D D + + IKP P S + T +A P
Sbjct: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985
Query: 1559 R 1559
+
Sbjct: 986 K 986
Score = 53.9 bits (128), Expect = 1e-06
Identities = 97/476 (20%), Positives = 161/476 (33%), Gaps = 59/476 (12%)
Query: 1034 PTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSG 1093
P ST S ++T ATP + + + PSS + + + +
Sbjct: 81 PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADL----PSSMKEKAKAETEKAGK 134
Query: 1094 SKSHHSHSSSSSSSAST-SGKMKSSKSEGSSSSKLSSSMYS--SQGSSGSSQSKNSSQSG 1150
+ + H ++ + A+ SGK +E S+++ L S S + G++ +G
Sbjct: 135 TGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAG 194
Query: 1151 GKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMK 1210
SS T SS + + KP KP+ + S+S + P G +P
Sbjct: 195 QADSSSEDTSS--SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
Query: 1211 PVPGTPPSSKAKSP------ISSGSGGSHMSGTSSSSGMKSSSGL-----------GSSG 1253
PP+ +AK P GS + + S +K+S + G+ G
Sbjct: 253 KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312
Query: 1254 SLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHG 1313
+ PP AS + SS + S+ ++P+ K K
Sbjct: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA-KALLQAKASGKTSQV 371
Query: 1314 VVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVD 1373
S P E P G + ++ GKRE+ + S+ S S
Sbjct: 372 GAASAPAKESPRKGAAPAPPGKTGPAVAKAQ-------AGKREEDSQSSSEESDSEEEAP 424
Query: 1374 SSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGS 1433
+ K S G +P ++A K ES +G P A + G
Sbjct: 425 AQAKPS-------------------GKAPQVRAASAPAK--ESPRKGAAP--APPRKTGP 461
Query: 1434 PLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPL 1489
K E S S S+ + L + + + KS Q P+S G+ PL
Sbjct: 462 AAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517
Score = 47.0 bits (110), Expect = 1e-04
Identities = 96/449 (21%), Positives = 156/449 (34%), Gaps = 45/449 (10%)
Query: 956 PLLTTGDLGKEKTQKRVKEGN---GTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKR 1012
P + K R+ +G G + S G +S + G +K + PK
Sbjct: 1033 PKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKL 1092
Query: 1013 KKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTV 1072
+ K+P S + + S+ GS+ G + P P T + + T
Sbjct: 1093 PEVQQATKAPESSDDSEDSS--DSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEET- 1149
Query: 1073 MVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMY 1132
SS + SG + ++S +S +T K+ SS S +SS++
Sbjct: 1150 --AAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATP-KLDSSPS-------VSSTLA 1199
Query: 1133 SSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLS----K 1188
+ G ++K +G SP T G + S +T K + NP S +
Sbjct: 1200 AKDDPDGKQEAKPQQAAG---MLSPKT-GGKEAASGTTPQKSRKPKKGAGNPQASTLALQ 1255
Query: 1189 PNISP---SHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKS 1245
NI+ P + AS +K + + K ++ SS G +S
Sbjct: 1256 SNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKE--------SSRKGWES 1307
Query: 1246 SSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTA 1305
S + +TP S G + S + +SKGK ++ K S
Sbjct: 1308 RKRKLSGDQPAARTPRSKKK---KKLGAGEGGEASVSPEKTSTTSKGK--AKRDKASGDV 1362
Query: 1306 VIDKLKHGVVTSGPGGEDPLDGQMGVST---NSSSHPMSSKHNMSGGEFQGKREKSDKDK 1362
K K + + G E + Q G+ T S+P S K + + +EK +K K
Sbjct: 1363 KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKK 1422
Query: 1363 --SKVSTSGSSVDSSKKTSESKNVGSTGV 1389
K ST S S KK + K V
Sbjct: 1423 KAKKASTKDSESPSQKKKKKKKKTAEQTV 1451
Score = 31.6 bits (70), Expect = 6.4
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Query: 952 GSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPK 1011
GSQG K++ ++ +++G GT K K+S D + K+K K
Sbjct: 1372 GSQG--------AKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1423
Query: 1012 RKKADT-EGKSPSHSSSNR 1029
KKA T + +SPS +
Sbjct: 1424 AKKASTKDSESPSQKKKKK 1442
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 68.9 bits (167), Expect = 4e-11
Identities = 120/586 (20%), Positives = 221/586 (37%), Gaps = 111/586 (18%)
Query: 992 PGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPP--------TSTGGSKSP 1043
PGK + + GK D +++D++G++P+ +S + PP + G + +P
Sbjct: 916 PGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATP 975
Query: 1044 GSAGRSQTPPGVATPP---------------IPKITIQIPK-GTVMVGKPSSHSQYTSSG 1087
A + TP IP P T +V P++H +
Sbjct: 976 AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKA 1035
Query: 1088 SVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK--N 1145
S++ + S S S + ++ S+ ++S S+S+ ++G++ + K
Sbjct: 1036 SMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSV-QAKGTNKLRKPKLPE 1094
Query: 1146 SSQSGGKPGSSPITKHGL--SSGSSSTKMKPQG-KPSSLMNPSLSKPNISPSHSRPPGGS 1202
Q+ P SS ++ SSGS PQG K + + P+ S+ +
Sbjct: 1095 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSE 1154
Query: 1203 DKLASPMKPV------PG-TPPSSKAKSPI----SSGSGGSHMSGTSSSSGMKSSSGLGS 1251
D + +P + + PG TP +S+A SS S S ++ G + + +
Sbjct: 1155 DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA 1214
Query: 1252 SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLK 1311
+G LS KT G ++S G +P +++KP
Sbjct: 1215 AGMLSPKT-----------------GGKEAAS--------GTTPQKSRKPK--------- 1240
Query: 1312 HGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGK-----REKSDKDKSKVS 1366
G +P + + +N + + ++ + Q E ++++ KV
Sbjct: 1241 -------KGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVV 1293
Query: 1367 TSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEG----LR 1422
+ + +SS+K ES+ K G P+ + + +K +GEG +
Sbjct: 1294 DT--TKESSRKGWESRK-----------RKLSGDQPAARTPRSKKKKKLGAGEGGEASVS 1340
Query: 1423 PQMASSKNYGSPL---ISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNS 1479
P+ S+ + G SG K ++G S A + E + G E Q++
Sbjct: 1341 PEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGA--KDEPEEELQKGMGTVEGGDQSN 1397
Query: 1480 PSSDDGIRPLPEYSTEKHKKHKKEK-KKVKDKDRDRDRDKDRDKKK 1524
P S + + +K KK KK+K KK KD + K + KKK
Sbjct: 1398 PKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKK 1443
Score = 54.7 bits (130), Expect = 7e-07
Identities = 138/721 (19%), Positives = 242/721 (33%), Gaps = 95/721 (13%)
Query: 872 SQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDF 931
SQ+++G EE + SS+ + + + A++AL + +G+T G A +
Sbjct: 328 SQTKAGKPEEDSESSSEESSDSEEETPAAKAL------LQAKASGKTSQVGAASAPAKES 381
Query: 932 SIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSK 991
K APA G GP + GK + + + S+S P
Sbjct: 382 P-----RKGAAPAP-----PGKTGPAVAKAQAGKREEDSQ--SSSEESDSEEEAPAQAKP 429
Query: 992 PGKRSRTPSNDGKSKDKP-------PKRK-----------KADTEGKSPSHSS-SNRPFT 1032
GK + + +K+ P P RK K + + +S S S S+R
Sbjct: 430 SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREAL 489
Query: 1033 PPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSS 1092
+ K G + + + + P+ K +P G V PS +
Sbjct: 490 AAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPS-----------AQV 538
Query: 1093 GSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGK 1152
G S SSS SS S+ G++ ++ + S L + + + K
Sbjct: 539 GKWEEDSESSSEESSDSSDGEVPTAVAPAQEKS-LGNILQA------------------K 579
Query: 1153 PGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPV 1212
P SSP +G + ++K + KP S + + S P + A P +
Sbjct: 580 PTSSPAKGPPQKAGPVAVQVKAE-KPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKI 638
Query: 1213 PGT--------PPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSN 1264
P T +S +P+ G+ +GT++S S + G +Q+ S+
Sbjct: 639 PQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGG----TQRPAEDSS 694
Query: 1265 SCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDP 1324
S S S +G +++ G +K K + V L G PG P
Sbjct: 695 SSEESDSEEEKTGLAVTV-----GQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP 749
Query: 1325 LDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNV 1384
Q+ S S S E K K + + ++ +++ S +
Sbjct: 750 TVTQVKAEKQEDS---ESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
Query: 1385 GSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASS--KNYGSPLISGSTPK 1442
+ G ++ SPS K K ++ P S+ P S K + + + P+
Sbjct: 807 SAPGKVVTAAAQAKQRSPS-KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 865
Query: 1443 HERGSPSHSKSPAYTPQNLDSESESGSS----IAEKSYQNSPSSDDGIRPLPEYSTEKHK 1498
+ GS + L SG + A + SP P + +
Sbjct: 866 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQ 925
Query: 1499 KHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPS 1558
K++ ++ D D + + IKP P S + T +A P
Sbjct: 926 AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR 985
Query: 1559 R 1559
+
Sbjct: 986 K 986
Score = 53.9 bits (128), Expect = 1e-06
Identities = 97/476 (20%), Positives = 161/476 (33%), Gaps = 59/476 (12%)
Query: 1034 PTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSG 1093
P ST S ++T ATP + + + PSS + + + +
Sbjct: 81 PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADL----PSSMKEKAKAETEKAGK 134
Query: 1094 SKSHHSHSSSSSSSAST-SGKMKSSKSEGSSSSKLSSSMYS--SQGSSGSSQSKNSSQSG 1150
+ + H ++ + A+ SGK +E S+++ L S S + G++ +G
Sbjct: 135 TGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAG 194
Query: 1151 GKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMK 1210
SS T SS + + KP KP+ + S+S + P G +P
Sbjct: 195 QADSSSEDTSS--SSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQV 252
Query: 1211 PVPGTPPSSKAKSP------ISSGSGGSHMSGTSSSSGMKSSSGL-----------GSSG 1253
PP+ +AK P GS + + S +K+S + G+ G
Sbjct: 253 KGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPG 312
Query: 1254 SLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHG 1313
+ PP AS + SS + S+ ++P+ K K
Sbjct: 313 KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA-KALLQAKASGKTSQV 371
Query: 1314 VVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVD 1373
S P E P G + ++ GKRE+ + S+ S S
Sbjct: 372 GAASAPAKESPRKGAAPAPPGKTGPAVAKAQ-------AGKREEDSQSSSEESDSEEEAP 424
Query: 1374 SSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGS 1433
+ K S G +P ++A K ES +G P A + G
Sbjct: 425 AQAKPS-------------------GKAPQVRAASAPAK--ESPRKGAAP--APPRKTGP 461
Query: 1434 PLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPL 1489
K E S S S+ + L + + + KS Q P+S G+ PL
Sbjct: 462 AAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPL 517
Score = 31.6 bits (70), Expect = 6.4
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Query: 952 GSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPK 1011
GSQG K++ ++ +++G GT K K+S D + K+K K
Sbjct: 1371 GSQG--------AKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKK 1422
Query: 1012 RKKADT-EGKSPSHSSSNR 1029
KKA T + +SPS +
Sbjct: 1423 AKKASTKDSESPSQKKKKK 1441
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,798,819
Number of Sequences: 37866
Number of extensions: 3893356
Number of successful extensions: 48603
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 470
Number of HSP's successfully gapped in prelim test: 1783
Number of HSP's that attempted gapping in prelim test: 21151
Number of HSP's gapped (non-prelim): 15113
length of query: 1581
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1465
effective length of database: 13,855,062
effective search space: 20297665830
effective search space used: 20297665830
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.