Guide to the Human Genome
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Search of human proteins with 28558975

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28558975 mediator complex subunit 17 [Homo sapiens]
         (651 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28558975 mediator complex subunit 17 [Homo sapiens]               1295   0.0  
gi|5453974 protein kinase N2 [Homo sapiens]                            33   0.63 
gi|41872646 cullin 7 [Homo sapiens]                                    33   0.82 
gi|148612829 RUN and TBC1 domain containing 1 isoform 2 [Homo sa...    33   0.82 
gi|148612795 RUN and TBC1 domain containing 1 isoform 1 [Homo sa...    33   0.82 
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...    33   1.1  
gi|239754979 PREDICTED: hypothetical protein [Homo sapiens]            32   1.4  
gi|61175232 hypothetical protein LOC221424 [Homo sapiens]              32   1.4  
gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]             32   1.8  
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa...    32   2.4  
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa...    32   2.4  
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa...    32   2.4  
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    31   3.1  
gi|57634514 SPANX-N2 protein [Homo sapiens]                            31   3.1  
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...    30   5.3  
gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo sa...    30   5.3  
gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo sap...    30   5.3  
gi|14589937 protocadherin 8 isoform 2 precursor [Homo sapiens]         30   5.3  
gi|6631102 protocadherin 8 isoform 1 precursor [Homo sapiens]          30   5.3  
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...    30   7.0  
gi|83779010 SECIS binding protein 2 [Homo sapiens]                     30   7.0  
gi|156071420 hypothetical protein LOC728912 [Homo sapiens]             30   7.0  
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho...    30   7.0  
gi|140161500 ankyrin repeat and sterile alpha motif domain conta...    30   7.0  
gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapi...    30   9.1  
gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapi...    30   9.1  
gi|154354998 inositol 1,4,5-triphosphate receptor, type 1 isofor...    30   9.1  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    30   9.1  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    30   9.1  
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    30   9.1  

>gi|28558975 mediator complex subunit 17 [Homo sapiens]
          Length = 651

 Score = 1295 bits (3351), Expect = 0.0
 Identities = 651/651 (100%), Positives = 651/651 (100%)

Query: 1   MSGVRAVRISIESACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEA 60
           MSGVRAVRISIESACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEA
Sbjct: 1   MSGVRAVRISIESACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEA 60

Query: 61  AGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVR 120
           AGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVR
Sbjct: 61  AGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVR 120

Query: 121 DKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQ 180
           DKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQ
Sbjct: 121 DKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQ 180

Query: 181 RDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDLDLDKKIPEDY 240
           RDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDLDLDKKIPEDY
Sbjct: 181 RDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDLDLDKKIPEDY 240

Query: 241 CPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQN 300
           CPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQN
Sbjct: 241 CPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQN 300

Query: 301 VLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATE 360
           VLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATE
Sbjct: 301 VLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATE 360

Query: 361 KQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINS 420
           KQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINS
Sbjct: 361 KQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINS 420

Query: 421 LQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLIT 480
           LQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLIT
Sbjct: 421 LQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLIT 480

Query: 481 SQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSYQEQELQDFLLSQMSQHQVHAVQQL 540
           SQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSYQEQELQDFLLSQMSQHQVHAVQQL
Sbjct: 481 SQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSYQEQELQDFLLSQMSQHQVHAVQQL 540

Query: 541 AKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQ 600
           AKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQ
Sbjct: 541 AKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQ 600

Query: 601 CKDLPKSDVLQDNKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL 651
           CKDLPKSDVLQDNKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL
Sbjct: 601 CKDLPKSDVLQDNKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL 651


>gi|5453974 protein kinase N2 [Homo sapiens]
          Length = 984

 Score = 33.5 bits (75), Expect = 0.63
 Identities = 35/173 (20%), Positives = 73/173 (42%), Gaps = 19/173 (10%)

Query: 4   VRAVRISIESACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEAAGT 63
           +  +R+ I  A   Q +E+  D  +  + PL +     R   RI+F+   G++       
Sbjct: 187 IEVIRMQILQAV--QTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAK------- 237

Query: 64  EGDAQEWPGAGSSADQDD-EEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVRDK 122
             +  +  G+G   D+    E   +F  S    D ++ +L   L E+   +    I+ ++
Sbjct: 238 --NVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEE 295

Query: 123 KFMTLDPVSQDALPPKQNPQTLQ----LISKKKSLAGAAQILLKGAERLTKSV 171
             +     +   L P+Q+  + Q     +SK  +L G  ++ L G + + ++V
Sbjct: 296 LSLV---AASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENV 345


>gi|41872646 cullin 7 [Homo sapiens]
          Length = 1698

 Score = 33.1 bits (74), Expect = 0.82
 Identities = 23/102 (22%), Positives = 55/102 (53%), Gaps = 1/102 (0%)

Query: 223 EVIKNTDLDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLP 282
           EV++    +LD +I +D    ++ +P +L     + +  +     + DL   +++K+  P
Sbjct: 511 EVLQILQENLDGEILDDEILAELAVPIELAQDLLLTLPQRLNDSALRDLINCHVYKKYGP 570

Query: 283 KSKPGSPHWQTKLEAAQNVLLC-KEIFAQLSREAVQIKSQVP 323
           ++  G+  + + LEA ++VLL   +  A+ S +A +++++ P
Sbjct: 571 EALAGNQAYPSLLEAQEDVLLLDAQAQAKDSEDAAKVEAKEP 612


>gi|148612829 RUN and TBC1 domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 1006

 Score = 33.1 bits (74), Expect = 0.82
 Identities = 19/69 (27%), Positives = 30/69 (43%)

Query: 13  SACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEAAGTEGDAQEWPG 72
           +A  +Q H V  D  ++ LP        + +   +D  Q  G EEE+  G EG +   P 
Sbjct: 689 TAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGGGEEGSSGPGPA 748

Query: 73  AGSSADQDD 81
           A +  +  D
Sbjct: 749 AHTLREPQD 757


>gi|148612795 RUN and TBC1 domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 1051

 Score = 33.1 bits (74), Expect = 0.82
 Identities = 19/69 (27%), Positives = 30/69 (43%)

Query: 13  SACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEAAGTEGDAQEWPG 72
           +A  +Q H V  D  ++ LP        + +   +D  Q  G EEE+  G EG +   P 
Sbjct: 734 TAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGGGEEGSSGPGPA 793

Query: 73  AGSSADQDD 81
           A +  +  D
Sbjct: 794 AHTLREPQD 802


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
           sapiens]
          Length = 4621

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 39/170 (22%), Positives = 72/170 (42%), Gaps = 13/170 (7%)

Query: 314 EAVQIKSQVPHIVVKNQIISQPFPSLQL-------SISLCHSSNDKKSQKFATEKQCPED 366
           E VQ KS  P  V K +    P  SL+        S   C S+   K+ K   E+     
Sbjct: 180 EKVQ-KSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNS 238

Query: 367 HLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINSLQSSEG 426
            L V   + H    +  +  L+ + +P P S+      +  +GP + +K E+N L+ +E 
Sbjct: 239 TLVVDRESSH----DECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEK 294

Query: 427 LLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVK 476
           L  ++ ++ K  F   +    +  LA  + + Q +  +    D+ +S ++
Sbjct: 295 LHPQLAEK-KQQFRNLKERCFVTQLAGFLANQQKKYKYEECKDLIKSMLR 343


>gi|239754979 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 780

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 18/82 (21%), Positives = 33/82 (40%), Gaps = 9/82 (10%)

Query: 42  RLAQRIDFSQGSGSEEEEAAGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNN 101
           ++A+ +  S  SG+    A G       W G G  A      G  +     WPW  + + 
Sbjct: 100 KMAEHLSLSDISGARTPAAGGRPSSGLLWVGPGLGA------GTAR---CFWPWALICSR 150

Query: 102 LRSALTEMCVLYDVLSIVRDKK 123
           +    +   +LY  L++  D++
Sbjct: 151 MAFVSSRRLLLYKALAVAEDRR 172


>gi|61175232 hypothetical protein LOC221424 [Homo sapiens]
          Length = 316

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 5/52 (9%)

Query: 24  LDGTETY---LPPLSMSQNLA--RLAQRIDFSQGSGSEEEEAAGTEGDAQEW 70
           LD  E Y   L  L +++N     L Q+I      G EEEE AG  GD QEW
Sbjct: 222 LDMVENYPTALRSLVLAENSISPELQQQICDLLSEGEEEEEVAGGAGDTQEW 273


>gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]
          Length = 420

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 44/199 (22%), Positives = 88/199 (44%), Gaps = 27/199 (13%)

Query: 408 SGPQAFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNI 467
           + P  +  N I +L+++      ++  AK +  R   A+T +        PQ + +W ++
Sbjct: 163 ASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQSEDYWGHV 222

Query: 468 NDV-----YESSVKVLITSQGYEQICKSIQLQLNIGVEQIRVVH--------RDGRVITL 514
           N +     Y+   +V       E +C +   Q  + V   R+ +         DGRV++ 
Sbjct: 223 NPIGPRACYDEGKRVA------ETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVS- 275

Query: 515 SYQEQELQ-DFLLSQMSQHQVHAVQQLAKVMGWQVLSFSNHVGLGPIESIGNASAITVAS 573
           ++  Q LQ + L    S  Q  A Q ++ ++   V   +++V   P+ ++GN    T+  
Sbjct: 276 NFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGLVALMNSNVS-SPV-NLGNPEEHTIL- 332

Query: 574 PSGDYAISVRNGPESGSKI 592
              ++A  ++N   SGS+I
Sbjct: 333 ---EFAQLIKNLVGSGSEI 348


>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
           sapiens]
          Length = 1181

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 11/119 (9%)

Query: 399 PFGHKRMRLSGPQAFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRAAATID--SLASRIE 456
           P GH +   +   + +  + NS   SE LLE  I  +   + +       D  S  S   
Sbjct: 213 PDGHSQGAPNSDPSLEPEDRNSTSVSEDLLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNS 272

Query: 457 DPQIQAHWSNINDVYESSVKVLITSQGYEQIC---------KSIQLQLNIGVEQIRVVH 506
           DP ++   SN     E  ++ L  ++  E+IC          ++ L  NIG+ + R ++
Sbjct: 273 DPGLEPEDSNSTSALEDPLEFLDMAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDIN 331


>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
           sapiens]
          Length = 1200

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 11/119 (9%)

Query: 399 PFGHKRMRLSGPQAFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRAAATID--SLASRIE 456
           P GH +   +   + +  + NS   SE LLE  I  +   + +       D  S  S   
Sbjct: 213 PDGHSQGAPNSDPSLEPEDRNSTSVSEDLLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNS 272

Query: 457 DPQIQAHWSNINDVYESSVKVLITSQGYEQIC---------KSIQLQLNIGVEQIRVVH 506
           DP ++   SN     E  ++ L  ++  E+IC          ++ L  NIG+ + R ++
Sbjct: 273 DPGLEPEDSNSTSALEDPLEFLDMAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDIN 331


>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
           sapiens]
          Length = 1226

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 28/119 (23%), Positives = 49/119 (41%), Gaps = 11/119 (9%)

Query: 399 PFGHKRMRLSGPQAFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRAAATID--SLASRIE 456
           P GH +   +   + +  + NS   SE LLE  I  +   + +       D  S  S   
Sbjct: 213 PDGHSQGAPNSDPSLEPEDRNSTSVSEDLLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNS 272

Query: 457 DPQIQAHWSNINDVYESSVKVLITSQGYEQIC---------KSIQLQLNIGVEQIRVVH 506
           DP ++   SN     E  ++ L  ++  E+IC          ++ L  NIG+ + R ++
Sbjct: 273 DPGLEPEDSNSTSALEDPLEFLDMAEIKEKICDYLFNVSDSSALNLAKNIGLTKARDIN 331


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 15/33 (45%), Positives = 20/33 (60%)

Query: 52  GSGSEEEEAAGTEGDAQEWPGAGSSADQDDEEG 84
           GS S E+  +G EGD+ E     SS++QD E G
Sbjct: 697 GSESGEQGESGEEGDSNEDSSEDSSSEQDSESG 729


>gi|57634514 SPANX-N2 protein [Homo sapiens]
          Length = 180

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 5/72 (6%)

Query: 17  KQVHEVGLD---GTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEAAGTEGDAQEWPGA 73
           ++  + GLD   G+      L  S+  ++  + +D S+GS  E+E+   +EG +QE    
Sbjct: 82  QEEEDEGLDSAEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDL 141

Query: 74  GSS--ADQDDEE 83
            SS  + Q+DE+
Sbjct: 142 DSSEGSSQEDED 153


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 7/55 (12%)

Query: 52   GSGSEEEEAAGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSAL 106
            G+G+E    AG E  A+   GAG+    +   GV       W WD     + S L
Sbjct: 1910 GAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGV-------WSWDGDATTVESRL 1957


>gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo
           sapiens]
          Length = 856

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 283 KSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLS 342
           K  PGS    +K EA+ N+ + K      + +  ++KS+  H   KN        +  + 
Sbjct: 16  KISPGSIK-DSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKKNLFERMEARAQAMQ 74

Query: 343 ISLCHSSNDKKSQKFATEKQCPEDHL 368
             +    N KK  +   EK+ P D+L
Sbjct: 75  QKIIDKENLKKELEKKAEKKLPRDNL 100


>gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo
           sapiens]
          Length = 1503

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 283 KSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLS 342
           K  PGS    +K EA+ N+ + K      + +  ++KS+  H   KN        +  + 
Sbjct: 72  KISPGSIK-DSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKKNLFERMEARAQAMQ 130

Query: 343 ISLCHSSNDKKSQKFATEKQCPEDHL 368
             +    N KK  +   EK+ P D+L
Sbjct: 131 QKIIDKENLKKELEKKAEKKLPRDNL 156


>gi|14589937 protocadherin 8 isoform 2 precursor [Homo sapiens]
          Length = 973

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 40/158 (25%), Positives = 71/158 (44%), Gaps = 18/158 (11%)

Query: 164 AERLTKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFE 223
           AE L   V+ +   +L + FNS LLR+R+      VGD  L     R  G        F+
Sbjct: 50  AEDLHMKVSGDTSFRLMKQFNSSLLRVREGDGQLTVGDAGLD--RERLCGQAPQCVLAFD 107

Query: 224 VI-------KNTDLDLDKKIPEDYCPL--DVQIPSDLEGSAYIKVSIQKQAPDIGDLGTV 274
           V+       +   ++++ +   D+ P     QIP ++   A +   I  + P   D+G  
Sbjct: 108 VVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGAN 167

Query: 275 NLFKRPLPKSKPGSP---HWQTKLEAAQ--NVLLCKEI 307
            L  + +  ++P SP     QT+ + AQ  +++L +E+
Sbjct: 168 GL--QTVRLAEPHSPFRVELQTRADGAQCADLVLLQEL 203


>gi|6631102 protocadherin 8 isoform 1 precursor [Homo sapiens]
          Length = 1070

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 40/158 (25%), Positives = 71/158 (44%), Gaps = 18/158 (11%)

Query: 164 AERLTKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFE 223
           AE L   V+ +   +L + FNS LLR+R+      VGD  L     R  G        F+
Sbjct: 50  AEDLHMKVSGDTSFRLMKQFNSSLLRVREGDGQLTVGDAGLD--RERLCGQAPQCVLAFD 107

Query: 224 VI-------KNTDLDLDKKIPEDYCPL--DVQIPSDLEGSAYIKVSIQKQAPDIGDLGTV 274
           V+       +   ++++ +   D+ P     QIP ++   A +   I  + P   D+G  
Sbjct: 108 VVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGAN 167

Query: 275 NLFKRPLPKSKPGSP---HWQTKLEAAQ--NVLLCKEI 307
            L  + +  ++P SP     QT+ + AQ  +++L +E+
Sbjct: 168 GL--QTVRLAEPHSPFRVELQTRADGAQCADLVLLQEL 203


>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 24/97 (24%), Positives = 52/97 (53%), Gaps = 12/97 (12%)

Query: 168 TKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKN 227
           TKSV+++ + +LQ  F++ +  +R H         +  D+ +++     P H T  +  +
Sbjct: 317 TKSVSKDTKIQLQVPFSATMSPVRLH----SSNPNLCADIEFQTP----PSHLTDPLESS 368

Query: 228 TDLDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQ 264
           TD     K+ E++C +  ++ S L+ SA+  ++I+K+
Sbjct: 369 TDY---TKLQEEFCLIAQKVHSLLK-SAFNSIAIEKE 401


>gi|83779010 SECIS binding protein 2 [Homo sapiens]
          Length = 854

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 21/96 (21%), Positives = 39/96 (40%), Gaps = 22/96 (22%)

Query: 32  PPLSMSQNLARLAQRIDFSQGSGSEEEEAAGTEG----------------------DAQE 69
           P  +  +++    Q+   SQGS  E+ EA+                          DA+E
Sbjct: 349 PSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEE 408

Query: 70  WPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSA 105
           +P    ++++ D     KFQ    P D+ +NN++ +
Sbjct: 409 FPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKS 444


>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
          Length = 790

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 34/174 (19%), Positives = 72/174 (41%), Gaps = 12/174 (6%)

Query: 310 QLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDK-------KSQKFATEKQ 362
           Q+  +   ++S  P  V K +    P  SL+     C +S+         K+ K   E+ 
Sbjct: 100 QVEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEED 159

Query: 363 CPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINSLQ 422
                L V   + H    +  +  L+ + +P P S+      +  +GP + +K E+N L+
Sbjct: 160 KVNSSLVVDRESSH----DGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE 215

Query: 423 SSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVK 476
            +E L  ++ ++ K  F   +    +  +A  +   Q +  +    D+ +S ++
Sbjct: 216 INEKLCPQLAEK-KQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLR 268


>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
           sapiens]
          Length = 790

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 34/174 (19%), Positives = 72/174 (41%), Gaps = 12/174 (6%)

Query: 310 QLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDK-------KSQKFATEKQ 362
           Q+  +   ++S  P  V K +    P  SL+     C +S+         K+ K   E+ 
Sbjct: 100 QVEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEED 159

Query: 363 CPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINSLQ 422
                L V   + H    +  +  L+ + +P P S+      +  +GP + +K E+N L+
Sbjct: 160 KVNSSLVVDRESSH----DGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE 215

Query: 423 SSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVK 476
            +E L  ++ ++ K  F   +    +  +A  +   Q +  +    D+ +S ++
Sbjct: 216 INEKLCPQLAEK-KQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLR 268


>gi|140161500 ankyrin repeat and sterile alpha motif domain
           containing 1 [Homo sapiens]
          Length = 1134

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 42/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%)

Query: 383 HKQTLSSIMMPHPASAPFGHK---RMR---LSGPQAFDKNEINSLQSSEGLLEKIIKQAK 436
           H +TL+    PHP  A  G +   R R    S P+A  K   +  +S   LL     +  
Sbjct: 580 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA 639

Query: 437 HIFLRSRAAATIDSLASRIE-DPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQL 495
            +  RS + +       R+E  P   + W  I  +  S  + +  SQ  ++I     L+ 
Sbjct: 640 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQ 699

Query: 496 NIG--VEQIRVVHRDGRVITLSY-----------QEQELQDFLLS--QMSQHQVHAVQQL 540
           ++G  +E I +   + +++   +           +EQ+L+D  +S  Q  +  + A + L
Sbjct: 700 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL 759

Query: 541 AKV 543
            KV
Sbjct: 760 PKV 762


>gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapiens]
          Length = 1906

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 15/49 (30%), Positives = 25/49 (51%)

Query: 227  NTDLDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVN 275
            N DL+   K+ E++C   +QIP++   +A  K  I   A  I   G ++
Sbjct: 1590 NFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLD 1638


>gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapiens]
          Length = 1863

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 15/49 (30%), Positives = 25/49 (51%)

Query: 227  NTDLDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVN 275
            N DL+   K+ E++C   +QIP++   +A  K  I   A  I   G ++
Sbjct: 1547 NFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLD 1595


>gi|154354998 inositol 1,4,5-triphosphate receptor, type 1 isoform 1
           [Homo sapiens]
          Length = 2710

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 9/73 (12%)

Query: 75  SSADQDDEEGVVKFQPSLWP-WDSVRNNLRSALTEMCVLYDVLSIVRD---KKFMTLDPV 130
           +  D D EE  ++FQPS+ P  D+ R+ LR+A  +M  +Y ++S+           LDP 
Sbjct: 316 AEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKM--VYSLVSVPEGNDISSIFELDPT 373

Query: 131 S---QDALPPKQN 140
           +    D+L P+ +
Sbjct: 374 TLRGGDSLVPRNS 386


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 37/165 (22%), Positives = 72/165 (43%), Gaps = 20/165 (12%)

Query: 352  KKSQKFATEKQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQ 411
            KK +    E Q  + ++   + NL+ L R++H   L S+       A  G  +   +  Q
Sbjct: 2347 KKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESL-----GRAMTGLIKKHEAVSQ 2401

Query: 412  AFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQI-QAHWSNINDV 470
               K + +  +S E    + +++ +  FL ++AAA   S   R  D ++ +A   ++ ++
Sbjct: 2402 LCSKTQASLQESLEKHFSESMQEFQEWFLGAKAAAKESS--DRTGDSKVLEAKLHDLQNI 2459

Query: 471  YES-----SVKVLITSQGY-------EQICKSIQLQLNIGVEQIR 503
             +S     S    +T +G        +QI  SIQ Q+    E+ +
Sbjct: 2460 LDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQ 2504


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 37/165 (22%), Positives = 72/165 (43%), Gaps = 20/165 (12%)

Query: 352  KKSQKFATEKQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQ 411
            KK +    E Q  + ++   + NL+ L R++H   L S+       A  G  +   +  Q
Sbjct: 2340 KKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESL-----GRAMTGLIKKHEAVSQ 2394

Query: 412  AFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQI-QAHWSNINDV 470
               K + +  +S E    + +++ +  FL ++AAA   S   R  D ++ +A   ++ ++
Sbjct: 2395 LCSKTQASLQESLEKHFSESMQEFQEWFLGAKAAAKESS--DRTGDSKVLEAKLHDLQNI 2452

Query: 471  YES-----SVKVLITSQGY-------EQICKSIQLQLNIGVEQIR 503
             +S     S    +T +G        +QI  SIQ Q+    E+ +
Sbjct: 2453 LDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQ 2497


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform
          3 [Homo sapiens]
          Length = 2059

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 13/31 (41%), Positives = 19/31 (61%)

Query: 56 EEEEAAGTEGDAQEWPGAGSSADQDDEEGVV 86
          EEEE  G E + +E   A    ++DD+EGV+
Sbjct: 22 EEEEEEGDEEEEEEVEAADEDDEEDDDEGVL 52


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,188,092
Number of Sequences: 37866
Number of extensions: 1074872
Number of successful extensions: 3590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3564
Number of HSP's gapped (non-prelim): 45
length of query: 651
length of database: 18,247,518
effective HSP length: 109
effective length of query: 542
effective length of database: 14,120,124
effective search space: 7653107208
effective search space used: 7653107208
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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