Guide to the Human Genome
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Search of human proteins with 28557777

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28557777 immunoglobulin-like domain containing receptor 1
[Homo sapiens]
         (502 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28557777 immunoglobulin-like domain containing receptor 1 [Ho...  1073   0.0  
gi|45505163 LISCH protein isoform 1 [Homo sapiens]                    207   1e-53
gi|45545424 LISCH protein isoform 2 [Homo sapiens]                    196   4e-50
gi|40786420 immunoglobulin-like domain containing receptor 2 [Ho...   188   1e-47
gi|45593136 LISCH protein isoform 3 [Homo sapiens]                    112   6e-25
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              56   7e-08
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          47   4e-05
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         45   2e-04
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    45   2e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        44   3e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         43   6e-04
gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain c...    42   0.001
gi|117676384 splicing factor, arginine/serine-rich 2, interactin...    42   0.002
gi|50083281 KIAA1853 protein [Homo sapiens]                            42   0.002
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  41   0.002
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             40   0.004
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     39   0.008
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s...    39   0.014
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]        39   0.014
gi|119226260 calcium homeostasis endoplasmic reticulum protein [...    39   0.014
gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]             38   0.019
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           38   0.019
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           38   0.019
gi|24307919 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Ho...    38   0.019
gi|32171215 CREB regulated transcription coactivator 2 [Homo sap...    38   0.025
gi|62244004 modulator of estrogen induced transcription isoform ...    37   0.032
gi|63176611 modulator of estrogen induced transcription isoform ...    37   0.032
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    37   0.032
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    37   0.032
gi|19923830 pre-B-cell leukemia homeobox interacting protein 1 [...    37   0.032

>gi|28557777 immunoglobulin-like domain containing receptor 1 [Homo
           sapiens]
          Length = 502

 Score = 1073 bits (2775), Expect = 0.0
 Identities = 502/502 (100%), Positives = 502/502 (100%)

Query: 1   MAWPKLPAPWLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTW 60
           MAWPKLPAPWLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTW
Sbjct: 1   MAWPKLPAPWLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTW 60

Query: 61  RFKSFCKDPIFDYYSASYQAALSLGQDPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQR 120
           RFKSFCKDPIFDYYSASYQAALSLGQDPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQR
Sbjct: 61  RFKSFCKDPIFDYYSASYQAALSLGQDPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQR 120

Query: 121 KITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALL 180
           KITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALL
Sbjct: 121 KITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALL 180

Query: 181 LLLLIGVCWCQCCPQYCCCYIRCPCCPAHCCCPEEDLSLPSSLPQMPMTQTTNQPPIANG 240
           LLLLIGVCWCQCCPQYCCCYIRCPCCPAHCCCPEEDLSLPSSLPQMPMTQTTNQPPIANG
Sbjct: 181 LLLLIGVCWCQCCPQYCCCYIRCPCCPAHCCCPEEDLSLPSSLPQMPMTQTTNQPPIANG 240

Query: 241 VLEYLEKELRNLNLAQPLPPDLKGRFGHPCSMLSSLGSEVVERRIIHLPPLIRDLSSSRR 300
           VLEYLEKELRNLNLAQPLPPDLKGRFGHPCSMLSSLGSEVVERRIIHLPPLIRDLSSSRR
Sbjct: 241 VLEYLEKELRNLNLAQPLPPDLKGRFGHPCSMLSSLGSEVVERRIIHLPPLIRDLSSSRR 300

Query: 301 TSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHR 360
           TSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHR
Sbjct: 301 TSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHR 360

Query: 361 SSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRR 420
           SSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRR
Sbjct: 361 SSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRR 420

Query: 421 HRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSR 480
           HRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSR
Sbjct: 421 HRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSR 480

Query: 481 KKGSVERRSEKDSSHSGRSVVI 502
           KKGSVERRSEKDSSHSGRSVVI
Sbjct: 481 KKGSVERRSEKDSSHSGRSVVI 502


>gi|45505163 LISCH protein isoform 1 [Homo sapiens]
          Length = 630

 Score =  207 bits (528), Expect = 1e-53
 Identities = 167/545 (30%), Positives = 226/545 (41%), Gaps = 101/545 (18%)

Query: 10  WLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTWRFKSFCKDP 69
           WLLL TW  A   ++ VTV +    V LF  + L C Y  ++     +V W++KSFC+D 
Sbjct: 76  WLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDR 135

Query: 70  IFDYYSAS--------YQAALSLGQDPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQRK 121
           I D +S +          AA + G +P  +C D+ R VR+VA ++G N   LG  Y+ R+
Sbjct: 136 IADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQG-NAVTLGDYYQGRR 194

Query: 122 ITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVLHWLTVIFIILGALLL 181
           ITI   ADL  ++  W D GVYYC++ +  D  G+ +   +LIVL WL V+ + L A L+
Sbjct: 195 ITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLDWLFVVVVCLAAFLI 254

Query: 182 LLLIGVCWCQCCPQYCCCYIRCPCCPAHCCCPEEDLSLPSSLPQMPMTQTTNQPPIANGV 241
            LL+G+CWCQCCP  CCCY+RCPCCP  CCCPE       +L       T+  P I    
Sbjct: 255 FLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPE-------ALYAAGKAATSGVPSI---- 303

Query: 242 LEYLEKELRNLNLAQPLPP-----------DLKGRFGHPCSMLSSLGSEVVERRIIHLPP 290
             Y      +L+ A+  PP              G +       SS G +          P
Sbjct: 304 --YAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGGQG------SYVP 355

Query: 291 LIRDLSSS-------------RRTSDS------LHQQWLTPIPSRPW--DLREGRSHHHY 329
           L+RD  SS              +  DS      + ++     PSRP     R  R+    
Sbjct: 356 LLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEV 415

Query: 330 PDFHQE----LQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSE 385
              H++       RGP    +     D  W G   S R   SP  W         P+  +
Sbjct: 416 TSLHEDDWRSRPSRGPALTPIR----DEEWGG--HSPR---SPRGWDQE------PAREQ 460

Query: 386 A--RWRPSHPPFRS-RCQERPRRPSPRESTQRH--GRRRRHRSYSPPLPSGLSSWSSEED 440
           A   WR   P  RS    +    PS  ES  R       R R+Y PP          ++D
Sbjct: 461 AGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDD 520

Query: 441 KERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNS-----------------RKKG 483
               P+S   H     S   P   P S+      P  N                  RKKG
Sbjct: 521 SRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKG 580

Query: 484 SVERR 488
           S ERR
Sbjct: 581 SEERR 585


>gi|45545424 LISCH protein isoform 2 [Homo sapiens]
          Length = 649

 Score =  196 bits (498), Expect = 4e-50
 Identities = 167/564 (29%), Positives = 226/564 (40%), Gaps = 120/564 (21%)

Query: 10  WLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTWRFKSFCKDP 69
           WLLL TW  A   ++ VTV +    V LF  + L C Y  ++     +V W++KSFC+D 
Sbjct: 76  WLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDR 135

Query: 70  IFDYYSAS--------YQAALSLGQDPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQRK 121
           I D +S +          AA + G +P  +C D+ R VR+VA ++G N   LG  Y+ R+
Sbjct: 136 IADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQG-NAVTLGDYYQGRR 194

Query: 122 ITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVL--------------- 166
           ITI   ADL  ++  W D GVYYC++ +  D  G+ +   +LIVL               
Sbjct: 195 ITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLGRTSGVAELLPGFQA 254

Query: 167 ----HWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPAHCCCPEEDLSLPSS 222
                WL V+ + L A L+ LL+G+CWCQCCP  CCCY+RCPCCP  CCCPE       +
Sbjct: 255 GPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPE-------A 307

Query: 223 LPQMPMTQTTNQPPIANGVLEYLEKELRNLNLAQPLPP-----------DLKGRFGHPCS 271
           L       T+  P I      Y      +L+ A+  PP              G +     
Sbjct: 308 LYAAGKAATSGVPSI------YAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVD 361

Query: 272 MLSSLGSEVVERRIIHLPPLIRDLSSS-------------RRTSDS------LHQQWLTP 312
             SS G +          PL+RD  SS              +  DS      + ++    
Sbjct: 362 RSSSAGGQG------SYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANF 415

Query: 313 IPSRPW--DLREGRSHHHYPDFHQE----LQDRGPKSWALERRELDPSWSGRHRSSRLNG 366
            PSRP     R  R+       H++       RGP    +     D  W G   S R   
Sbjct: 416 DPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIR----DEEWGG--HSPR--- 466

Query: 367 SPIHWSDRDSLSDVPSSSEA--RWRPSHPPFRS-RCQERPRRPSPRESTQRH--GRRRRH 421
           SP  W         P+  +A   WR   P  RS    +    PS  ES  R       R 
Sbjct: 467 SPRGWDQE------PAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRS 520

Query: 422 RSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNS-- 479
           R+Y PP          ++D    P+S   H     S   P   P S+      P  N   
Sbjct: 521 RAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSR 580

Query: 480 ---------------RKKGSVERR 488
                          RKKGS ERR
Sbjct: 581 SGDLPYDGRLLEEAVRKKGSEERR 604


>gi|40786420 immunoglobulin-like domain containing receptor 2 [Homo
           sapiens]
          Length = 639

 Score =  188 bits (477), Expect = 1e-47
 Identities = 117/345 (33%), Positives = 165/345 (47%), Gaps = 82/345 (23%)

Query: 10  WLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTWRFKSFCKDP 69
           W+ L  WL A    L VTV   ++   LF   +L+C ++TS+  Q  VV W+FKS+C+D 
Sbjct: 8   WISLF-WLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSH-QPAVVQWKFKSYCQDR 65

Query: 70  IFDYYSASYQAALSLGQ-----DPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQRKITI 124
           + +    S   A SL +     DP  DC D++R VR+VA ++G     LG  YR R+ITI
Sbjct: 66  MGESLGMSSTRAQSLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTV-TLGDFYRGREITI 124

Query: 125 QNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVL------------------ 166
            + ADL I ++MW D G+YYC I  P D  G  +  V+L+VL                  
Sbjct: 125 VHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFAVEIM 184

Query: 167 -HWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPAHCCCPE----------- 214
             W+ V  ++LG  L  +L+G+CWCQCCP  CCCY+RCPCCP  CCCP+           
Sbjct: 185 PEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGKAAKA 244

Query: 215 ------EDLSLPSSLPQMP---------MTQTTNQPPIANG------------------- 240
                   +  P S+P +P         +    + PP+A                     
Sbjct: 245 GYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRIQADK 304

Query: 241 ------VLEYLEKELRNLNLAQPLPPDLKGRFGHPCSMLSSLGSE 279
                 VL Y+EKEL   + A+     ++GR+ +  S LSSL  E
Sbjct: 305 ERDSMKVLYYVEKELAQFDPAR----RMRGRYNNTISELSSLHEE 345


>gi|45593136 LISCH protein isoform 3 [Homo sapiens]
          Length = 581

 Score =  112 bits (281), Expect = 6e-25
 Identities = 62/165 (37%), Positives = 91/165 (55%), Gaps = 9/165 (5%)

Query: 10  WLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTWRFKSFCKDP 69
           WLLL TW  A   ++ VTV +    V LF  + L C Y  ++     +V W++KSFC+D 
Sbjct: 76  WLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDR 135

Query: 70  IFDYYSA--------SYQAALSLGQDPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQRK 121
           I D +S         +  AA + G +P  +C D+ R VR+VA ++G N   LG  Y+ R+
Sbjct: 136 IADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQG-NAVTLGDYYQGRR 194

Query: 122 ITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVL 166
           ITI   ADL  ++  W D GVYYC++ +  D  G+ +   +LIVL
Sbjct: 195 ITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL 239



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 68/245 (27%), Positives = 90/245 (36%), Gaps = 54/245 (22%)

Query: 241 VLEYLEKELRNLNLAQPLPPDLKGRFGHPCSMLSSLGSEVVERRIIHLPPL--IRDLS-- 296
           VL Y+EKEL N + ++P PP   GR     S ++SL  +    R    P L  IRD    
Sbjct: 336 VLYYMEKELANFDPSRPGPPS--GRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWG 393

Query: 297 -SSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELDPSW 355
             S R+     Q+         W  R  R+          L D  P S A        S 
Sbjct: 394 GHSPRSPRGWDQEPAREQAGGGWRARRPRARSV-----DALDDLTPPSTAESGSRSPTSN 448

Query: 356 SGRHRSSR--LNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERP---------R 404
            GR R+     + S     D+D   D P S +    P +  FRSR  ERP         R
Sbjct: 449 GGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRD----PHYDDFRSR--ERPPADPRSHHHR 502

Query: 405 RPSPRESTQRHG--------------------RRRRHR-----SYSPPLPSGLSSWSSEE 439
              PR++  R G                    RRR H+     +Y PP P   S   S+ 
Sbjct: 503 TRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQA 562

Query: 440 DKERQ 444
            +ER+
Sbjct: 563 SRERR 567


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 71/213 (33%), Positives = 88/213 (41%), Gaps = 45/213 (21%)

Query: 316  RPWD--LREGRSH--HHYPDFHQELQDRGPKSWALERRELDPSW----SGRHRSSRLNGS 367
            R W   L++  +H  H++P F++E   RGP     ER   +PSW    S   RS R +  
Sbjct: 1524 RTWHRHLKDKLTHKEHNHPSFYRERTPRGPS----ERTRHNPSWRNHRSPSERSQRSSLE 1579

Query: 368  PIHWSDRD------SLSDVPSSSEARWR-PSH-----PPFRSRCQERPRR--PSPRESTQ 413
              H S         S  +  S SE  WR PS      PP RS C     R   SP + + 
Sbjct: 1580 RRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERS-CHSLSERGLHSPSQRSH 1638

Query: 414  RHGRRRRHRS---YSPPLPSGLSSWSSEEDKERQPQSWRAHR----RGSHSPHWPEEKPP 466
            R   +RRH S    S   PS  S  SS E + R P S R+HR    R   SP     + P
Sbjct: 1639 RGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSP-SQRSHRGPSERSHCSPSERRHRSP 1697

Query: 467  SYRSLDITPGKNSRKKGSVERRSEKDSSHSGRS 499
            S RS           +G  ERR    S  S RS
Sbjct: 1698 SQRS----------HRGPSERRHHSPSKRSHRS 1720



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 63/208 (30%), Positives = 78/208 (37%), Gaps = 35/208 (16%)

Query: 296  SSSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHYPD--FHQELQDRGPKSWALERRELDP 353
            S   R+  SL ++ L   PS+       +  HH P    H+   +R  +S + ERR   P
Sbjct: 1616 SPPERSCHSLSERGLHS-PSQRSHRGPSQRRHHSPSERSHRSPSERSHRS-SSERRHRSP 1673

Query: 354  SW-SGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWR-PSHPPFRSRCQERPRRPSPRES 411
            S  S R  S R + SP               SE R R PS    R   + R   PS R  
Sbjct: 1674 SQRSHRGPSERSHCSP---------------SERRHRSPSQRSHRGPSERRHHSPSKR-- 1716

Query: 412  TQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSL 471
            + R   RR HRS     PS  S  S  E     P       R  HSP       PS RS 
Sbjct: 1717 SHRSPARRSHRS-----PSERSHHSPSERSHHSPS-----ERRHHSPSERSHCSPSERS- 1765

Query: 472  DITPGKNSRKKGSVERRSEKDSSHSGRS 499
              +P +  R +   ERR    S  S  S
Sbjct: 1766 HCSPSER-RHRSPSERRHHSPSEKSHHS 1792



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 15/180 (8%)

Query: 324  RSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRS--SRLNGSPIHWSDRDSLSDVP 381
            RSHH   +               ER    PS   RHRS   R + SP   S   S S+  
Sbjct: 1740 RSHHSPSERRHHSPSERSHCSPSERSHCSPS-ERRHRSPSERRHHSPSEKSHH-SPSERS 1797

Query: 382  SSSEARWRPSHPPFRSR---CQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSE 438
              S +  R   P  RSR    +   R PS R S +   R  R  S     PS  S  S  
Sbjct: 1798 HHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPL 1857

Query: 439  EDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSSHSGR 498
            E     P   R H     + H P E+  S+RS       +  ++G    RS + S    R
Sbjct: 1858 ERSRCSPSERRGHSSSGKTCHSPSER--SHRS------PSGMRQGRTSERSHRSSCERTR 1909



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 65/244 (26%), Positives = 77/244 (31%), Gaps = 37/244 (15%)

Query: 270  CSMLSSLGSEVVERRIIHLPPLIRDLSSSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHY 329
            C  LS  G     +R    P   R  S S R+  S         PS           H  
Sbjct: 1622 CHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRS---------PSERSHRSSSERRHRS 1672

Query: 330  PDFHQELQDRGPKSWA----LERRELDPSW-SGRHRSSRLNGSPIHWSDRDSL--SDVPS 382
            P    +   RGP   +     ERR   PS  S R  S R + SP   S R     S    
Sbjct: 1673 PS---QRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSP 1729

Query: 383  SSEARWRPSHPPFRSRCQERPRRPS------PRESTQRHGRRRRHRSYSPPLPSGLSSWS 436
            S  +   PS     S  + R   PS      P E +      RRHRS     PS     S
Sbjct: 1730 SERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRS-----PSERRHHS 1784

Query: 437  SEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSSHS 496
              E     P       R  HSP       P  RS      ++ R     ERRS +    S
Sbjct: 1785 PSEKSHHSPS-----ERSHHSPSERRRHSPLERSRHSLLERSHRSPS--ERRSHRSFERS 1837

Query: 497  GRSV 500
             R +
Sbjct: 1838 HRRI 1841


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 63/218 (28%), Positives = 80/218 (36%), Gaps = 19/218 (8%)

Query: 289 PPLIRDLSSSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALER 348
           P   RD S SR  S       L   PS+  D R  RS        +E Q R  +S + ER
Sbjct: 467 PNKARDRSRSRSPSKERDHSQLGS-PSKERDHRRSRSPS------KERQCRQSRSSSKER 519

Query: 349 RELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSP 408
                    + R  R + SP    +RD       S E   R S  P + R + R R PS 
Sbjct: 520 DHRRSRSPSKERQRRQSRSPN--KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSK 577

Query: 409 ----RESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPH--WPE 462
               R+S      R   RS SP   SG S   +   ++   +S    + G+HS      +
Sbjct: 578 ERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSK 637

Query: 463 EKPPSY----RSLDITPGKNSRKKGSVERRSEKDSSHS 496
           E  PS     RS D           S  R   K SSHS
Sbjct: 638 ESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHS 675



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 38/144 (26%), Positives = 51/144 (35%), Gaps = 14/144 (9%)

Query: 359 HRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQR-HGR 417
           H  SR        S + + S V S S   W+ +H   RSR ++       R S  R H +
Sbjct: 281 HSQSRSPRRSRSGSQKRTHSRVRSHS---WKRNHSRARSRTRKGILSQMGRHSQSRSHSK 337

Query: 418 RRRHRSYSPPLPSGLSSWSSEEDKER-----QPQSWRAHRRGSHSPHWPEEKPPSYRSLD 472
            +       P      +WS    KER     +  S     RGS SP     +  S RS  
Sbjct: 338 GKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSP-----RKESGRSQS 392

Query: 473 ITPGKNSRKKGSVERRSEKDSSHS 496
            +P K      S      +D S S
Sbjct: 393 GSPNKQRDHSRSRSPNKARDRSRS 416


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 58/206 (28%), Positives = 75/206 (36%), Gaps = 57/206 (27%)

Query: 293 RDLSSSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELD 352
           R   +    S S   Q   P P+ PWD ++ RS           +DR P S A       
Sbjct: 525 RSGEAKEAASSSSGTQPAPPAPASPWDSKKHRS-----------RDRKPGSHA------- 566

Query: 353 PSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPREST 412
            S S R RS                        +R R      RSR  +R RR   R S 
Sbjct: 567 -SSSARRRS-----------------------RSRSRSRSTRRRSRSTDR-RRGGSRRSR 601

Query: 413 QRHGRRRRHRSYSPPLPSGLSSWSSEE-------------DKERQPQSWRAHRRGSHSPH 459
            R  RRRR RS SPP  +  SS S  E              K+++ +S    R G  S  
Sbjct: 602 SREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEK 661

Query: 460 WPEEKPPSYRSLDITPGKNSRKKGSV 485
            P   PP   S      ++SR++G+V
Sbjct: 662 APAPAPPPSGSTS-CGDRDSRRRGAV 686


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 43/149 (28%), Positives = 58/149 (38%), Gaps = 12/149 (8%)

Query: 360  RSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQ-ERPRRPSPRESTQRHGRR 418
            +++RLN  P    +++S SD  + S      S  P RSR + E   R   R  +  H R 
Sbjct: 1283 KTARLNRRP---RNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRS 1339

Query: 419  R--------RHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRS 470
            R        R RSYS     G  S      +    +S+++HR  S S        P  RS
Sbjct: 1340 RSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRS 1399

Query: 471  LDITPGKNSRKKGSVERRSEKDSSHSGRS 499
               T      +  S  R    DS H GRS
Sbjct: 1400 RSYTYDSYYSRSRSRSRSQRSDSYHRGRS 1428



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 397 SRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSH 456
           S+  +R    SPR  ++    R   RSY+        S +S   + R P S R+H R  +
Sbjct: 679 SKYSDRSSESSPRSRSRSSRSRSYSRSYTRS-----RSLASSHSRSRSPSS-RSHSRNKY 732

Query: 457 SPHWPEEKPPSYRSLDITPGKNSRK--KGSVERRSEKDSSHSGRS 499
           S H    +  SY S+    G+ +++  + S ++ S     HS  S
Sbjct: 733 SDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSS 777



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 3/100 (3%)

Query: 368 PIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPP 427
           P H    DS S+  SSSE+         RSR ++  RRP  + S +R  R+    S  P 
Sbjct: 192 PTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKR--RKEASSSEEPR 249

Query: 428 LPSGLS-SWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPP 466
               ++    SE     + +S  +  +       PEE PP
Sbjct: 250 NKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPP 289


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 44/164 (26%), Positives = 63/164 (38%), Gaps = 34/164 (20%)

Query: 356 SGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRH 415
           S    +++   SP    D+D         ++  RPS  P RS     P  P+P  + +RH
Sbjct: 322 SSPETATKQPSSPYEDKDKDK------KEKSATRPSPSPERSSTGPEPPAPTPLLA-ERH 374

Query: 416 GRRRRH--------------------RSYSPPL-PSGLSSWSSEEDKERQPQSWRAHRRG 454
           G   +                     R  SPP  P  L   SS E     PQ  +  R  
Sbjct: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHA 434

Query: 455 SHSPHWPEEKPP--SYRSLDITPGKNSRKKGSVERRSEKDSSHS 496
           S SP  P+  P   S+R +  +P   +R  G    R+++D SHS
Sbjct: 435 SSSPESPKPAPAPGSHREISSSPTSKNRSHG----RAKRDKSHS 474



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 55/173 (31%), Positives = 68/173 (39%), Gaps = 26/173 (15%)

Query: 321 REGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDV 380
           R GRSH   P        RG        R   P+  GR RS     +P   + R S S  
Sbjct: 558 RRGRSHSRSP------ATRG------RSRSRTPARRGRSRSR----TP---ARRRSRSRT 598

Query: 381 PSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEED 440
           P+   +R   S  P R R + R R P+ R S  R   RRR RS SP   SG S  S    
Sbjct: 599 PTRRRSR---SRTPAR-RGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSR-SRTPA 653

Query: 441 KERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDS 493
           +  + +S    RRG      P  +  S RS   TP +  R +    RR    S
Sbjct: 654 RRGRSRSRTPARRGRSRSRTPARR--SGRSRSRTPARRGRSRSRTPRRGRSRS 704



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 58/179 (32%), Positives = 73/179 (40%), Gaps = 27/179 (15%)

Query: 334  QELQDRGPKSWALERRELDPSWSGRHRS-------SRLNGSP-----IHWSDRDSLSDVP 381
            QEL D  P +   ER E D S   + ++       SR   SP        S R S S   
Sbjct: 1543 QEL-DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSG-- 1599

Query: 382  SSSEARWRPSHPPFR---SRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSE 438
            SS E + +P   P     S     P+ P+PR +  R  R         P P G S  S+E
Sbjct: 1600 SSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR-ALPRRSRSGSSSKGRGPSPEGSS--STE 1656

Query: 439  EDKERQPQSWRAHRRGSHSPHWPEEK---PPSYRSLDITPGKNSRKKGSVERRSEKDSS 494
               E  P+S R  RRGS S   P+ K   PP  RS   +P     +K  + RRS   SS
Sbjct: 1657 SSPEHPPKS-RTARRGSRSSPEPKTKSRTPPRRRSSRSSP--ELTRKARLSRRSRSASS 1712



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 35/124 (28%), Positives = 46/124 (37%), Gaps = 20/124 (16%)

Query: 383  SSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKE 442
            SS     P HPP +SR   R  R SP   T+     RR  S S P            +  
Sbjct: 1652 SSSTESSPEHPP-KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSP------------ELT 1698

Query: 443  RQPQSWRAHRRGSHSPHWPEEKPPSYRSL-------DITPGKNSRKKGSVERRSEKDSSH 495
            R+ +  R  R  S SP      PP +R              ++SR++ S      K +S 
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758

Query: 496  SGRS 499
             GRS
Sbjct: 1759 RGRS 1762



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 66/222 (29%), Positives = 86/222 (38%), Gaps = 40/222 (18%)

Query: 293 RDLSSSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALER-REL 351
           R++SSS  + +  H +            +  +SH H P      + R P +    R R  
Sbjct: 451 REISSSPTSKNRSHGR-----------AKRDKSHSHTPSRRMG-RSRSPATAKRGRSRSR 498

Query: 352 DPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRP--SPR 409
            P+  G  RS     SP  W          S S  RW  S  P R      P+RP  S  
Sbjct: 499 TPTKRGHSRSR----SP-QWRR--------SRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545

Query: 410 ESTQRHGR---RRRHRSYS-PPLPSGLSSWSSEEDKERQPQSWRAHRRG-SHSP--HWPE 462
            +TQR GR    RR RS+S  P   G S   +   + R      A RR  S +P      
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605

Query: 463 EKPPSY--RSLDITPG-KNSRKKGSVERRSEKDS--SHSGRS 499
            + P+   RS   TP  + SR +  V RRS   S    SGRS
Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRS 647



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 51/184 (27%), Positives = 67/184 (36%), Gaps = 21/184 (11%)

Query: 321 REGRSHHHYP---------DFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHW 371
           R GRS    P            +  + R P   +   R   P+  GR RS     +P   
Sbjct: 611 RRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSR----TPARR 666

Query: 372 SDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQR-HGRRRRHRSYSPPLPS 430
               S S  P+    R R   P  R R + R    +PR    R     RR RS+S     
Sbjct: 667 GR--SRSRTPARRSGRSRSRTPARRGRSRSR----TPRRGRSRSRSLVRRGRSHSRTPQR 720

Query: 431 GLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSE 490
              S SS E K +   S R  R  S SP   + +  S RS  ++  ++  K     RRS 
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNS-SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSL 779

Query: 491 KDSS 494
             SS
Sbjct: 780 SGSS 783



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 48/177 (27%), Positives = 60/177 (33%), Gaps = 17/177 (9%)

Query: 321 REGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDV 380
           R GRS    P      + R P+      R L        R+ +  G     S+R + S  
Sbjct: 677 RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT 736

Query: 381 PSSSEARWRPSHPPFRSRCQERPRRP--SPRESTQRHGRRRRHRSYSPPLPSGLSSWSSE 438
            S   +R   S    +SR   R  R   SPR   +     RR  S S P P         
Sbjct: 737 -SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP--------- 786

Query: 439 EDKERQPQSWRAHRRGSHSPHWPEEKPP-SYRSLDITPGKNSRKKGSVERRSEKDSS 494
             K++     R  R GS  P      PP   RS    P K   K  S  R+S   SS
Sbjct: 787 --KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS--RQSHSSSS 839



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 64/246 (26%), Positives = 87/246 (35%), Gaps = 23/246 (9%)

Query: 260  PDLKGRFGHPCSMLSSLGSEVVERRIIHLPPLIRDLSSSRRT-SDSLHQQWLTPIPSRPW 318
            P+ K +   P    SS  S  + R+   L    R  SSS  T S +  +   +P  S P 
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKA-RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPE 1734

Query: 319  DLREGRSHHHYPDFHQELQDRGPKSWALERRELDPS------WSGRHRSSRLNGSPIHWS 372
               + RS        +      P++    RR   PS         R RS R         
Sbjct: 1735 PAEKSRSSR------RRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR 1788

Query: 373  DRDSLSDVPSSSEARWRPSHPPFRSR---CQERPRRPSPRESTQRHGRRRRHRSYSPPLP 429
            DR   S   S    R R      R R        R P+ +ES++   RRRR RS +PP  
Sbjct: 1789 DRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTS 1848

Query: 430  SGLSSWSSEE---DKERQPQSWRAHRRG-SHSPHWPEEKPPSYRSLDITPGKNSRKKGSV 485
               S   +      + R   S   HRR  S +P     +  S  S      + SR + SV
Sbjct: 1849 RKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS--PVSRRRSRSRTSV 1906

Query: 486  ERRSEK 491
             RR  +
Sbjct: 1907 TRRRSR 1912



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 29/177 (16%)

Query: 311  TPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIH 370
            +P P+    +REGR                P     +RR    S S    SS  + S   
Sbjct: 2581 SPTPAPKEAVREGRPPE-------------PTPAKRKRRSSSSSSSSSSSSSSSSSSSSS 2627

Query: 371  WSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRR----------- 419
             S   S S   SSS +    S  P +   Q  P+  SP++      R R           
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRD 2687

Query: 420  -RHRSYSP---PLPSGLSSWSSEEDKERQPQSWRAHRRGSHSP-HWPEEKPPSYRSL 471
             R  SYSP     PS   S   ++    +  S R  R  S SP H    + PS R +
Sbjct: 2688 SRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPM 2744



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 44/165 (26%), Positives = 59/165 (35%), Gaps = 18/165 (10%)

Query: 337  QDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFR 396
            + R P S  L  + L P        S ++   +  +     S   SS E   +PS  P  
Sbjct: 1496 RSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP-- 1553

Query: 397  SRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSH 456
               QER    S  +S  +     R RS          S SS E   +   S R  R GS 
Sbjct: 1554 ---QERSESDSSPDSKAKTRTPLRQRS---------RSGSSPEVDSKSRLSPRRSRSGS- 1600

Query: 457  SPHW---PEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSSHSGR 498
            SP     P   P +    D +P   +    ++ RRS   SS  GR
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 49/181 (27%), Positives = 64/181 (35%), Gaps = 14/181 (7%)

Query: 315  SRPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDR 374
            SR   +   RS    P   +  + R P       R   P  + R   SR   SPI     
Sbjct: 1925 SRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRT--SPITRRRS 1982

Query: 375  DSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRH--GRRRRHRSYSPPLPSGL 432
             S +   +   +R R S P  R R + R    + R S  R     RRR RS +P LP   
Sbjct: 1983 RSRTSPVTRRRSRSRTS-PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKR 2041

Query: 433  SSWSS-----EEDKERQPQSWRAHRRGSHSPHWPEEK----PPSYRSLDITPGKNSRKKG 483
            S   S        + R P++ R  R  + SP     +      S RS   TP       G
Sbjct: 2042 SRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSG 2101

Query: 484  S 484
            S
Sbjct: 2102 S 2102



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 32/132 (24%), Positives = 46/132 (34%), Gaps = 9/132 (6%)

Query: 373 DRDSLSDVPSSSEARWRPSHPP-----FRSRCQERPRRPSPRESTQRHGRRRRHRSYSPP 427
           D  S      + EA+     PP      R     R   P  ++  ++  R RR  S SP 
Sbjct: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206

Query: 428 LPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSR---KKGS 484
                SS   +   E + +  R HR  +       +     RS   TP   SR   +  S
Sbjct: 207 RERKKSSKKKKHRSESESKK-RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTS 265

Query: 485 VERRSEKDSSHS 496
            +  S  D+S S
Sbjct: 266 ADSASSSDTSRS 277



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 37/141 (26%), Positives = 49/141 (34%), Gaps = 19/141 (13%)

Query: 373  DRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGL 432
            D + +  VP+          PP  +  Q+    PS   + Q   + RR  S S    S  
Sbjct: 2489 DHNGMLSVPAPGVPHSDVGEPPASTGAQQ----PSALAALQP-AKERRSSSSSSSSSSSS 2543

Query: 433  SSWSSEEDKERQPQSWRAHRRGSHSPHWPE---EKPPSY-----------RSLDITPGKN 478
            SS SS         S  +   GS  P  PE   ++ PS            R  + TP K 
Sbjct: 2544 SSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKR 2603

Query: 479  SRKKGSVERRSEKDSSHSGRS 499
             R+  S    S   SS S  S
Sbjct: 2604 KRRSSSSSSSSSSSSSSSSSS 2624


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 52/154 (33%), Positives = 66/154 (42%), Gaps = 23/154 (14%)

Query: 348 RRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRR-- 405
           +R+ + S  GR R S    SP     R S S  P     R  P+ PP R      PRR  
Sbjct: 535 KRQKETSPRGRRRRSP---SPPPTRRRRSPSPAPPPRRRR-TPTPPPRRRTPSPPPRRRS 590

Query: 406 PSPRESTQRHGRRRRHRSYSP-PLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEK 464
           PSPR  +    RR     YSP P P   ++      K R   S    RR SHSP      
Sbjct: 591 PSPRRYSPPIQRR-----YSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSP------ 639

Query: 465 PPSYRSLDIT----PGKNSR-KKGSVERRSEKDS 493
           PP  RS  +T    P  +S+ +KGS   RS +++
Sbjct: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREA 673



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 57/213 (26%), Positives = 71/213 (33%), Gaps = 49/213 (23%)

Query: 290 PLIRDLSSSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDR-GPKSWALER 348
           P  R  S SR  + S      +P  +RP      RS  + P      + R  P+     R
Sbjct: 276 PRSRSRSKSRSRTRSR-----SPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPR 330

Query: 349 RELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSP 408
           R   P    RHR SR   SP+    R S S   SSS +          SR +  P++P  
Sbjct: 331 RMPPPP---RHRRSR---SPVRRRRRSSASLSGSSSSSS--------SSRSRSPPKKPPK 376

Query: 409 RESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSY 468
           R S+     RR   S SPP                         R  H P  P   PP  
Sbjct: 377 RTSSPPRKTRRLSPSASPP-------------------------RRRHRPSPPATPPPKT 411

Query: 469 RSLDITPGKNSRKKGSVE----RRSEKDSSHSG 497
           R        N  +K  V     R S K + H G
Sbjct: 412 RHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG 444



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 30/104 (28%), Positives = 39/104 (37%), Gaps = 25/104 (24%)

Query: 396 RSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGS 455
           RS+ + R R  SP  +  R   R R RSYSP                R+P   R      
Sbjct: 281 RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP---------------RRRPSPRRRPSPRR 325

Query: 456 HSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSSHSGRS 499
            +P  P   PP        P ++ R +  V RR    +S SG S
Sbjct: 326 RTP--PRRMPP--------PPRHRRSRSPVRRRRRSSASLSGSS 359



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 39/140 (27%), Positives = 51/140 (36%), Gaps = 25/140 (17%)

Query: 373 DRDSLSDVPSSSEARWRPSHPPFRSRCQERPRR---PSPRESTQRHGRRRRHRSYS---- 425
           D+    +  SS E R R   P  R      PRR   P  RE  + H R  RHR+ S    
Sbjct: 152 DKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPS 211

Query: 426 ---------PPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPG 476
                    P LP    S   +E   ++  S     +       PE K PS       P 
Sbjct: 212 PAPEKKEKTPELPE--PSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS-------PE 262

Query: 477 KNSRKKGSVERRSEKDSSHS 496
           KNS+K+   E+   +  S S
Sbjct: 263 KNSKKEKEKEKTRPRSRSRS 282



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 38/135 (28%), Positives = 53/135 (39%), Gaps = 9/135 (6%)

Query: 337 QDRGPKSWALERRELDPSWSGRHR-SSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPF 395
           +D+G K  A +  +    +  +++ SS  +GS     D         + E   R  H P 
Sbjct: 467 EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526

Query: 396 RSRCQERPRRPSPRE-STQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRG 454
           RS        PSPR+   +   R RR RS SPP      S S      R+       RR 
Sbjct: 527 RSAS------PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRR 580

Query: 455 SHSPHWPEEKPPSYR 469
           + SP  P  + PS R
Sbjct: 581 TPSPP-PRRRSPSPR 594


>gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing A [Homo sapiens]
          Length = 312

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 41/123 (33%), Positives = 49/123 (39%), Gaps = 19/123 (15%)

Query: 347 ERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRP 406
           E+ E  PS   R RS R         D D     P+    R R   P  RSR  +R R P
Sbjct: 202 EKLERVPSPDHRRRSYR---------DLDKPRRSPTLRYRRSRSRSPRRRSRSPKR-RSP 251

Query: 407 SPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPP 466
           SPR        R RHRS SP      S       + + P   R+HR  SHS   PE    
Sbjct: 252 SPR--------RERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKS-PERSKK 302

Query: 467 SYR 469
           S++
Sbjct: 303 SHK 305


>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
           protein [Homo sapiens]
          Length = 1463

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 39/151 (25%), Positives = 60/151 (39%), Gaps = 9/151 (5%)

Query: 351 LDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRE 410
           +D +   R R SR +     WS      D P   +    PS      +   + + PSP+ 
Sbjct: 781 IDKTKKPRTRRSRFHSPSTTWSPN---KDTPQEKKRPQSPSPRRETGKESRKSQSPSPKN 837

Query: 411 STQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWP---EEKPPS 467
            + R   R++ RS SP          S+    ++  +  + R  S SP      E K   
Sbjct: 838 ESAR--GRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQ 895

Query: 468 YRSLDITPGKNSRKKGSVERRSEKDSSHSGR 498
            R  D +PG+ SR + S ER S++D     R
Sbjct: 896 PRVKDSSPGEKSRSQ-SRERESDRDGQRRER 925


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 50/184 (27%), Positives = 69/184 (37%), Gaps = 15/184 (8%)

Query: 322 EGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVP 381
           E RS+   P +  +   R P S +   R   PS+S R+  SR       +S++DS     
Sbjct: 425 EKRSYSRSPSYSSKSGKRSPPSRSSRSRR-SPSYS-RYSPSRERDPK--YSEKDSQQRER 480

Query: 382 SSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLP------SGLSSW 435
             +  R R S+ P R R ++ P     R  T     R+R   Y  P P      S  SSW
Sbjct: 481 ERARRR-RRSYSPMRKRRRDSPSHLEARRIT---SARKRPIPYYRPSPSSSGSLSSTSSW 536

Query: 436 SSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSSH 495
            S        +S+   R  S S      +  S  S   +P   SR +     RS   S  
Sbjct: 537 YSSSSSRSASRSYSRSRSRSRSRRRSRTRTSS-SSSSRSPSPGSRSRSRSRSRSRSRSRS 595

Query: 496 SGRS 499
             RS
Sbjct: 596 QSRS 599



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 18/117 (15%)

Query: 393 PPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHR 452
           PP  SR +++ ++     ST++  +RRR  SYSP         SS++ K R+  S +  R
Sbjct: 102 PPPSSRGKKKKKK-----STRK--KRRRSSSYSPSPVKKKKKKSSKKHKRRRSFS-KKRR 153

Query: 453 RGSHSPHWPEEKPPSYRSLDIT-PGKN---------SRKKGSVERRSEKDSSHSGRS 499
             S SP         ++    + P K+         SR + S  R S  +S H GRS
Sbjct: 154 HSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRS 210


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 47/156 (30%), Positives = 64/156 (41%), Gaps = 21/156 (13%)

Query: 339 RGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSR 398
           +G  S+    RE   S   R RS R+  S  H  DR       S    R+R      R R
Sbjct: 553 KGKHSYNSRTRERSRS---RDRSRRVR-SRTHDRDRSR-----SKEYHRYREQEYRRRGR 603

Query: 399 CQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSP 458
            + R RR  P  S  +  RRRR  S S        S S  +DK R  +S  +HR+ +   
Sbjct: 604 SRSRERRTPPGRSRSKDRRRRRRDSRSSERE---ESQSRNKDKYRNQESKSSHRKENSE- 659

Query: 459 HWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSS 494
               EK    +S D     NSR     E+++++D S
Sbjct: 660 ---SEKRMYSKSRDHNSSNNSR-----EKKADRDQS 687



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 23/139 (16%)

Query: 358 RHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGR 417
           RH+SS  + S    SD DS SD  SSS++    S     +  + + R+   R+++++H +
Sbjct: 190 RHKSSSSSSSSS--SDSDSSSDSQSSSDS----SDSESATEEKSKKRKKKHRKNSRKHKK 243

Query: 418 RRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPP----SYRSLDI 473
            ++ R  S       SS S  E+ E QPQS             PEE PP     +     
Sbjct: 244 EKKKRKKS---KKSASSESEAENLEAQPQSTVR----------PEEIPPIPENRFLMRKS 290

Query: 474 TPGKNSRKKGSVERRSEKD 492
            P  + +++ + ER  E++
Sbjct: 291 PPKADEKERKNRERERERE 309


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 51/174 (29%), Positives = 63/174 (36%), Gaps = 19/174 (10%)

Query: 342 KSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRP-------SHPP 394
           KS    RR+   S S R R  R   S     +++     P +     R        SH P
Sbjct: 204 KSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSP 263

Query: 395 FRSRCQERPRRPSP-----RESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWR 449
             S      R PS      R+  ++ G +R   S SP  PSG S W S +      Q   
Sbjct: 264 SLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPS-PSGGSGWGSPQRNGGSGQRSG 322

Query: 450 AHRRGSHSPHWPEEKP--PSYRSLD----ITPGKNSRKKGSVERRSEKDSSHSG 497
           AH     S H P +KP  PS R  D      P   +R K S   RS   S   G
Sbjct: 323 AHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRG 376



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 47/179 (26%), Positives = 63/179 (35%), Gaps = 27/179 (15%)

Query: 322 EGRSHHHYPDFHQELQDRGPKSWALER---RELDPSWSGRHRSSRLNGSPIHWSDRDS-- 376
           EG+S    P  H       P+SW+  R   +    S   R  S   + SP     RD   
Sbjct: 484 EGKSSSRSPGPH-------PRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG 536

Query: 377 -----LSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSG 431
                 S+  ++   R   S+ P R R ++ P    PR  T     R+R   Y  P PS 
Sbjct: 537 EGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRIT---SARKRPIPYYRPSPSS 593

Query: 432 ----LSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVE 486
               LSS  S     R P    +H   S   H    +    RS   TP  +   + S E
Sbjct: 594 SSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRT---RSPSRTPSPSYHSRSSSE 649



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 39/147 (26%), Positives = 51/147 (34%), Gaps = 18/147 (12%)

Query: 357 GRHRS-SRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQR- 414
           G  RS SR   S    S R +    P     R    H     R +ERP R  P  ++   
Sbjct: 418 GSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHG---KRAKERPPRARPASTSPSP 474

Query: 415 --HGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLD 472
             HGRR            G    SS       P+SW + R  S S     EK P   S  
Sbjct: 475 GAHGRR-----------GGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRS 523

Query: 473 ITPGKNSRKKGSVERRSEKDSSHSGRS 499
            +P K   +    E R+    + + R+
Sbjct: 524 PSPKKPLSRDKDGEGRARHSEAEATRA 550



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 41/145 (28%), Positives = 56/145 (38%), Gaps = 16/145 (11%)

Query: 368 PIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPREST--QRHGRRRRH---- 421
           P    +  S    PSS     R +    R R + R RR S   ++  +R GRRR      
Sbjct: 357 PARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPP 416

Query: 422 RSYSPPLPSGLSSWSSEEDKER-----QPQSWRAHRRGSHSPHWPEEKPPSYR--SLDIT 474
           R  S  L    SS  S   +       +P S R H  G H     +E+PP  R  S   +
Sbjct: 417 RGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGH--GGHGKR-AKERPPRARPASTSPS 473

Query: 475 PGKNSRKKGSVERRSEKDSSHSGRS 499
           PG + R+ G   + S +      RS
Sbjct: 474 PGAHGRRGGPEGKSSSRSPGPHPRS 498


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 39/124 (31%), Positives = 54/124 (43%), Gaps = 19/124 (15%)

Query: 393 PPFR--SRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQ--PQSW 448
           PP R  S+ ++ PR     +  ++H +R R RS SP   S   S S    K +   P ++
Sbjct: 737 PPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAY 796

Query: 449 RAHRRG---SHSP----HWPEEK------PPSYRSLDITPGKNSRKKGSVERRSEKDSSH 495
           R  RR    S SP    H PE +      P +YR +  +PG  SRK+       EK    
Sbjct: 797 RTVRRSRSRSRSPRRRAHSPERRREERSVPTAYR-VSRSPGA-SRKRTRSRSPHEKKKKR 854

Query: 496 SGRS 499
             RS
Sbjct: 855 RSRS 858


>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
            sapiens]
          Length = 2506

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 49/189 (25%), Positives = 66/189 (34%), Gaps = 35/189 (18%)

Query: 316  RPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRD 375
            RP D R+ R HHH+   H          +A ER +       R R  R + SP       
Sbjct: 2201 RPKD-RKHRQHHHHHHHHHHPPPPDKDRYAQERPD---HGRARARDQRWSRSP------- 2249

Query: 376  SLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRR---------RRHRSYSP 426
                    SE R   +H    S     P   +   ST R GRR         R H SYSP
Sbjct: 2250 --------SEGREHMAHRQGSSSVSGSPAPSTSGTSTPRRGRRQLPQTPSTPRPHVSYSP 2301

Query: 427  PL--PSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKP-----PSYRSLDITPGKNS 479
             +    G      ++ +++Q Q     R G  +   P   P     P       T G +S
Sbjct: 2302 VIRKAGGSGPPQQQQQQQQQQQQQAVARPGRAATSGPRRYPGPTAEPLAGDRPPTGGHSS 2361

Query: 480  RKKGSVERR 488
             +   +ERR
Sbjct: 2362 GRSPRMERR 2370



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 24/79 (30%), Positives = 31/79 (39%), Gaps = 20/79 (25%)

Query: 408  PRESTQRHGRRRRHRSYSPP---------LPSGLSSW-----------SSEEDKERQPQS 447
            P E  QRH +RRR RS+            + +GL +            S E D+ER    
Sbjct: 2144 PPEENQRHHQRRRDRSHRASERSLGRYTDVDTGLGTDLSMTTQSGDLPSKERDQERGRPK 2203

Query: 448  WRAHRRGSHSPHWPEEKPP 466
             R HR+  H  H     PP
Sbjct: 2204 DRKHRQHHHHHHHHHHPPP 2222



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 19/60 (31%), Positives = 24/60 (40%), Gaps = 7/60 (11%)

Query: 396  RSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGS 455
            R R   RP    P +  +R   R RHR  S P   G       +  ER+    R HR G+
Sbjct: 957  RHRAHRRPGEEGPEDKAER---RARHREGSRPARGGEGEGEGPDGGERR----RRHRHGA 1009


>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
          Length = 1337

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 44/154 (28%), Positives = 57/154 (37%), Gaps = 12/154 (7%)

Query: 298 SRRTSDSLHQQWLTP--IPSRPWDLREGRSHHHYPDFHQE--LQDRGPKSWALERRELDP 353
           S   S S H + L P  +P  P + R      HY D         RG +  +L+RRE   
Sbjct: 195 SANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGR 254

Query: 354 SWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQ 413
           S   R + SR        SD D     PS   +  R S    R R + R  R SP     
Sbjct: 255 SPDRRRQDSRYR------SDYDR-GRTPSRHRSYER-SRERERERHRHRDNRRSPSLERS 306

Query: 414 RHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQS 447
                +R  S SP      + W  E+D+    QS
Sbjct: 307 YKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQS 340


>gi|119226260 calcium homeostasis endoplasmic reticulum protein
           [Homo sapiens]
          Length = 916

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 55/192 (28%), Positives = 75/192 (39%), Gaps = 24/192 (12%)

Query: 261 DLKGRFGHPCSMLSSLGSEVVERRIIHLPPLIRDLSSSRRTSDSLHQQWLTPIPSRPWDL 320
           DL      P   L     + ++ + I LPP    +  S R   ++   +  P   RP + 
Sbjct: 649 DLPAGLMAPLVKLEDHEYKPLDPKDIRLPP---PMPPSERLLAAVEAFYSPPSHDRPRNS 705

Query: 321 REGRSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDV 380
                +  Y  F  +++ R  K    E+R   PS S     SR   S    S  +S S  
Sbjct: 706 EGWEQNGLYEFFRAKMRARRRKGQ--EKRNSGPSRSRSRSKSRGRSS----SRSNSRSSK 759

Query: 381 PSSSEARWRP-----SHPPFRSRCQERPRRPSPRESTQRH--------GRRRRHRSYSPP 427
            S S +R R      S+   RSR + R R    R  +Q          GRRRR RS SP 
Sbjct: 760 SSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPT 819

Query: 428 LPS--GLSSWSS 437
            PS  GL S S+
Sbjct: 820 PPSSAGLGSNSA 831


>gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]
          Length = 611

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 53/216 (24%), Positives = 94/216 (43%), Gaps = 19/216 (8%)

Query: 297 SSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWA--LERRELDPS 354
           S+RR + S  QQ  TP+  + + LR+ RS     +   +  DR  K+ A   E     P+
Sbjct: 73  STRRVTRS--QQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPT 130

Query: 355 WSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQE----RPRRPSPRE 410
            +     S ++ S  + S  +S++   S  ++    SH P R R  E      + P+P  
Sbjct: 131 GNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGC 190

Query: 411 STQRH--GRRRRHRSYSP-PLPSGLSSWSSE---EDKERQ-PQSWRAHRRGSHSPHWPEE 463
           ++  H  G+  RH S S  PL   LS+   +   + +++Q  +   +HR+  ++ H    
Sbjct: 191 NSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQDDNNRHATRH 250

Query: 464 KPPSYRSL----DITPGKNSRKKGSVERRSEKDSSH 495
           + P+ R L     +   +  R  G  + + EK   H
Sbjct: 251 QAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEH 286


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 47/173 (27%), Positives = 67/173 (38%), Gaps = 17/173 (9%)

Query: 331  DFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRP 390
            D H++ +    +    + ++ D S   R RS R   S      R S S   +   +    
Sbjct: 1798 DTHEKSKKNKNRDKGEKEKKRDSSL--RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK 1855

Query: 391  SH-PPFRSRCQERPRRPSPRESTQRHGRR---RRHRSYSPPLPSGLSSWSSEEDKERQPQ 446
            SH    RSR + R RR S R  ++  GRR   +  R  SP              K R+ +
Sbjct: 1856 SHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSP----------KHRSKSRERK 1905

Query: 447  SWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSSHSGRS 499
              R+  R +        + PS RS   TP +  R + SV RR     S S RS
Sbjct: 1906 RKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSR-SVGRRRSFSISPSRRS 1957



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 46/169 (27%), Positives = 58/169 (34%), Gaps = 28/169 (16%)

Query: 324  RSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSS 383
            RS           + RG +S + E+R+  P    +HRS                    S 
Sbjct: 1866 RSRRRRRSSRSRSKSRGRRSVSKEKRKRSP----KHRSK-------------------SR 1902

Query: 384  SEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLS-SWSSEEDKE 442
               R R S    R   + R R PS R  +    RRRR RS        +S S  S     
Sbjct: 1903 ERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962

Query: 443  RQPQSWRAHRRGSHSPHWP--EEKPPSYRSLDITPGKNSRKKGSVERRS 489
            R     R  R  S     P    + PS RS   TP +  R +  V RRS
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR--TPSRRRRSRSVVRRRS 2009


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 47/173 (27%), Positives = 67/173 (38%), Gaps = 17/173 (9%)

Query: 331  DFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRP 390
            D H++ +    +    + ++ D S   R RS R   S      R S S   +   +    
Sbjct: 1798 DTHEKSKKNKNRDKGEKEKKRDSSL--RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK 1855

Query: 391  SH-PPFRSRCQERPRRPSPRESTQRHGRR---RRHRSYSPPLPSGLSSWSSEEDKERQPQ 446
            SH    RSR + R RR S R  ++  GRR   +  R  SP              K R+ +
Sbjct: 1856 SHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSP----------KHRSKSRERK 1905

Query: 447  SWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSSHSGRS 499
              R+  R +        + PS RS   TP +  R + SV RR     S S RS
Sbjct: 1906 RKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSR-SVGRRRSFSISPSRRS 1957



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 46/169 (27%), Positives = 58/169 (34%), Gaps = 28/169 (16%)

Query: 324  RSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSS 383
            RS           + RG +S + E+R+  P    +HRS                    S 
Sbjct: 1866 RSRRRRRSSRSRSKSRGRRSVSKEKRKRSP----KHRSK-------------------SR 1902

Query: 384  SEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLS-SWSSEEDKE 442
               R R S    R   + R R PS R  +    RRRR RS        +S S  S     
Sbjct: 1903 ERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962

Query: 443  RQPQSWRAHRRGSHSPHWP--EEKPPSYRSLDITPGKNSRKKGSVERRS 489
            R     R  R  S     P    + PS RS   TP +  R +  V RRS
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR--TPSRRRRSRSVVRRRS 2009


>gi|24307919 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Homo
           sapiens]
          Length = 155

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 37/104 (35%), Positives = 42/104 (40%), Gaps = 9/104 (8%)

Query: 382 SSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRR--RRHRSYSPPLPSGLSSWSSEE 439
           S S +R R      RSR +ER RR S   S  R   R  RRHRS SP  PS L     EE
Sbjct: 16  SRSTSRERERRRRERSRSRERDRRRSRSRSPHRRRSRSPRRHRSTSPS-PSRLKERRDEE 74

Query: 440 DKE------RQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGK 477
            KE      ++ Q       G         K   + S D T GK
Sbjct: 75  KKETKETKSKERQITEEDLEGKTEEEIEMMKLMGFASFDSTKGK 118



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 15/96 (15%)

Query: 396 RSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGS 455
           RSR   R RR S R +++   RRRR RS             S E   R+ +S   HRR S
Sbjct: 5   RSRSPRRERRRS-RSTSRERERRRRERS------------RSRERDRRRSRSRSPHRRRS 51

Query: 456 HSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEK 491
            SP       PS   L     ++  KK + E +S++
Sbjct: 52  RSPRRHRSTSPSPSRL--KERRDEEKKETKETKSKE 85


>gi|32171215 CREB regulated transcription coactivator 2 [Homo
           sapiens]
          Length = 693

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 54/201 (26%), Positives = 73/201 (36%), Gaps = 16/201 (7%)

Query: 245 LEKELRNLNLAQPLP---PDLKGRFGHPCSMLSSLGSEVVERRIIHLPPLIRDLSSSRRT 301
           L+  L N NL   L    P L+G   HP    SSL   V+    +  P L     SS  +
Sbjct: 343 LQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSS 402

Query: 302 SDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELDPSWS---GR 358
           S S     L   PS P        HH            GP      +++L   +S     
Sbjct: 403 SSSTSSPVL-GAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSP 461

Query: 359 HRSSRLNGSPIHWSDRDS---LSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRH 415
             SS   G P+  S   +   L   P SS +   P+  P   +  ++P  PS   S Q  
Sbjct: 462 TLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQ-PHTPKSLQQPGLPSQSCSVQSS 520

Query: 416 -----GRRRRHRSYSPPLPSG 431
                GR+  + +  PP PSG
Sbjct: 521 GGQPPGRQSHYGTPYPPGPSG 541


>gi|62244004 modulator of estrogen induced transcription isoform b
           [Homo sapiens]
          Length = 1016

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 44/178 (24%), Positives = 64/178 (35%), Gaps = 13/178 (7%)

Query: 324 RSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSS 383
           R  + + DF    + R P+S A++    +       +S      P    +  S    P +
Sbjct: 745 RQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKN 804

Query: 384 SEARWRPSHPPFRSRCQERPRRPSPRESTQR-----HGR----RRRHRSYSPPLPSGLSS 434
                R   PP R+  +E  RR    E  +R     H R      RH   + P PS  +S
Sbjct: 805 FSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTS 864

Query: 435 WSSE---EDKERQPQSWRAHRRGSH-SPHWPEEKPPSYRSLDITPGKNSRKKGSVERR 488
           W SE      +R+ +  R  R G   S H     PP  RS     G     +G +  R
Sbjct: 865 WKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDR 922


>gi|63176611 modulator of estrogen induced transcription isoform a
           [Homo sapiens]
          Length = 1034

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 44/178 (24%), Positives = 64/178 (35%), Gaps = 13/178 (7%)

Query: 324 RSHHHYPDFHQELQDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSS 383
           R  + + DF    + R P+S A++    +       +S      P    +  S    P +
Sbjct: 763 RQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKN 822

Query: 384 SEARWRPSHPPFRSRCQERPRRPSPRESTQR-----HGR----RRRHRSYSPPLPSGLSS 434
                R   PP R+  +E  RR    E  +R     H R      RH   + P PS  +S
Sbjct: 823 FSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTS 882

Query: 435 WSSE---EDKERQPQSWRAHRRGSH-SPHWPEEKPPSYRSLDITPGKNSRKKGSVERR 488
           W SE      +R+ +  R  R G   S H     PP  RS     G     +G +  R
Sbjct: 883 WKSEGSMSTDKRETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDR 940


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 1/114 (0%)

Query: 382 SSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDK 441
           S S+ R R SH   RSR ++R R  SP +   +   RR+ RS S        +    ++K
Sbjct: 329 SQSKHRSR-SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK 387

Query: 442 ERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSSH 495
           ER  +  R   R        E++    +  D    K+  K    +R  E++  H
Sbjct: 388 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH 441



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 35/123 (28%), Positives = 44/123 (35%), Gaps = 7/123 (5%)

Query: 374 RDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLS 433
           +D  S  P  S    R S    R R + R R  S    T +  +R+  RS   P P   +
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PSPRSRN 529

Query: 434 SWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDS 493
               + +KER   S R  R  S S             L+    KNS      E   E DS
Sbjct: 530 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE----KNSTSLKEKEHNKEPDS 585

Query: 494 SHS 496
           S S
Sbjct: 586 SVS 588


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 1/114 (0%)

Query: 382 SSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDK 441
           S S+ R R SH   RSR ++R R  SP +   +   RR+ RS S        +    ++K
Sbjct: 213 SQSKHRSR-SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK 271

Query: 442 ERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDSSH 495
           ER  +  R   R        E++    +  D    K+  K    +R  E++  H
Sbjct: 272 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH 325



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 35/123 (28%), Positives = 44/123 (35%), Gaps = 7/123 (5%)

Query: 374 RDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLS 433
           +D  S  P  S    R S    R R + R R  S    T +  +R+  RS   P P   +
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PSPRSRN 413

Query: 434 SWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNSRKKGSVERRSEKDS 493
               + +KER   S R  R  S S             L+    KNS      E   E DS
Sbjct: 414 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE----KNSTSLKEKEHNKEPDS 469

Query: 494 SHS 496
           S S
Sbjct: 470 SVS 472


>gi|19923830 pre-B-cell leukemia homeobox interacting protein 1
           [Homo sapiens]
          Length = 731

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 37/137 (27%), Positives = 54/137 (39%), Gaps = 38/137 (27%)

Query: 337 QDRGPKSWALERRELDPSWSGRHRSSRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFR 396
           +DR  + W  ++ E     SGR R     G      DR+           RW+   P   
Sbjct: 483 RDRKAEHWKHKKEE-----SGRERKKNWGGQ----EDREPAG--------RWKEGRPRVE 525

Query: 397 -SRCQERPRRPSPRESTQRHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGS 455
            S  ++  +R  P+E               PP  SG  S+ S  +K++QP+ WR   + S
Sbjct: 526 ESGSKKEGKRQGPKE---------------PPRKSG--SFHSSGEKQKQPR-WREGTKDS 567

Query: 456 HS--PHWPEEKPPSYRS 470
           H   P W E   P YR+
Sbjct: 568 HDPLPSWAELLRPKYRA 584


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,922,384
Number of Sequences: 37866
Number of extensions: 1285493
Number of successful extensions: 7026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 250
Number of HSP's that attempted gapping in prelim test: 6076
Number of HSP's gapped (non-prelim): 995
length of query: 502
length of database: 18,247,518
effective HSP length: 107
effective length of query: 395
effective length of database: 14,195,856
effective search space: 5607363120
effective search space used: 5607363120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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