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Search of human proteins with 28372563
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28372563 growth arrest-specific 2 like 3 [Homo sapiens]
(694 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28372563 growth arrest-specific 2 like 3 [Homo sapiens] 1395 0.0
gi|219842340 growth arrest-specific 2 [Homo sapiens] 342 5e-94
gi|29540559 growth arrest-specific 2 [Homo sapiens] 342 5e-94
gi|4885253 growth arrest-specific 2 [Homo sapiens] 342 5e-94
gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens] 183 5e-46
gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo sapi... 166 7e-41
gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo sapi... 166 7e-41
gi|23065529 growth arrest-specific 2 like 1 isoform b [Homo sapi... 154 3e-37
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 74 3e-13
gi|33188445 microfilament and actin filament cross-linker protei... 73 8e-13
gi|33188443 microfilament and actin filament cross-linker protei... 67 7e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 62 1e-09
gi|91982772 mucin 17 [Homo sapiens] 61 4e-09
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 59 2e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 58 3e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 58 3e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 58 3e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 58 3e-08
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 58 3e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 57 8e-08
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 56 1e-07
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 56 1e-07
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 56 1e-07
gi|221316624 dystonin isoform 4 [Homo sapiens] 55 2e-07
gi|221316622 dystonin isoform 3 [Homo sapiens] 55 2e-07
gi|221316618 dystonin isoform 2 [Homo sapiens] 55 2e-07
gi|34577047 dystonin isoform 1 [Homo sapiens] 55 2e-07
gi|34577049 dystonin isoform 1eA precursor [Homo sapiens] 55 2e-07
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 55 3e-07
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 55 3e-07
>gi|28372563 growth arrest-specific 2 like 3 [Homo sapiens]
Length = 694
Score = 1395 bits (3611), Expect = 0.0
Identities = 694/694 (100%), Positives = 694/694 (100%)
Query: 1 MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSG 60
MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSG
Sbjct: 1 MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSG 60
Query: 61 LLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFF 120
LLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFF
Sbjct: 61 LLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFF 120
Query: 121 ARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVK 180
ARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVK
Sbjct: 121 ARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVK 180
Query: 181 LEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEG 240
LEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEG
Sbjct: 181 LEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEG 240
Query: 241 RYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVS 300
RYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVS
Sbjct: 241 RYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVS 300
Query: 301 NESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLK 360
NESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLK
Sbjct: 301 NESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLK 360
Query: 361 GGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPA 420
GGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPA
Sbjct: 361 GGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPA 420
Query: 421 LPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHIS 480
LPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHIS
Sbjct: 421 LPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHIS 480
Query: 481 SRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPS 540
SRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPS
Sbjct: 481 SRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPS 540
Query: 541 DGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKT 600
DGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKT
Sbjct: 541 DGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKT 600
Query: 601 GPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPS 660
GPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPS
Sbjct: 601 GPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPS 660
Query: 661 SVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK 694
SVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK
Sbjct: 661 SVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK 694
>gi|219842340 growth arrest-specific 2 [Homo sapiens]
Length = 313
Score = 342 bits (878), Expect = 5e-94
Identities = 170/299 (56%), Positives = 215/299 (71%), Gaps = 15/299 (5%)
Query: 24 RHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQ 83
R GPGL+++ QY +W+A RHEA LLPM+EDL++WL+ LLG ++ AE +E+LDNG LLCQ
Sbjct: 10 RSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQ 69
Query: 84 LIDVLQNMVKTCN--SEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETY 141
L + +Q K ++ + N P++K+PCK A SGSFFARDNTANFL WCRD+GVDET
Sbjct: 70 LAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLGVDETC 129
Query: 142 LFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTS-GPEDS 200
LFESEGLVLHK PR+V LCLLE+GRI +RYGVEPP L+KLEKEIE EETL S P S
Sbjct: 130 LFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPS 189
Query: 201 ISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVM 260
L +AVK I+EDPPC C ++F +E LS+GRYR+G+KILFIRMLH KHVM
Sbjct: 190 SKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFIRMLHNKHVM 249
Query: 261 VRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNP 319
VRVGGGW+T G+LLK+DPCR+LQ + ++ K Q +++P +MNP
Sbjct: 250 VRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQ------------SKSPTLKDMNP 296
>gi|29540559 growth arrest-specific 2 [Homo sapiens]
Length = 313
Score = 342 bits (878), Expect = 5e-94
Identities = 170/299 (56%), Positives = 215/299 (71%), Gaps = 15/299 (5%)
Query: 24 RHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQ 83
R GPGL+++ QY +W+A RHEA LLPM+EDL++WL+ LLG ++ AE +E+LDNG LLCQ
Sbjct: 10 RSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQ 69
Query: 84 LIDVLQNMVKTCN--SEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETY 141
L + +Q K ++ + N P++K+PCK A SGSFFARDNTANFL WCRD+GVDET
Sbjct: 70 LAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLGVDETC 129
Query: 142 LFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTS-GPEDS 200
LFESEGLVLHK PR+V LCLLE+GRI +RYGVEPP L+KLEKEIE EETL S P S
Sbjct: 130 LFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPS 189
Query: 201 ISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVM 260
L +AVK I+EDPPC C ++F +E LS+GRYR+G+KILFIRMLH KHVM
Sbjct: 190 SKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFIRMLHNKHVM 249
Query: 261 VRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNP 319
VRVGGGW+T G+LLK+DPCR+LQ + ++ K Q +++P +MNP
Sbjct: 250 VRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQ------------SKSPTLKDMNP 296
>gi|4885253 growth arrest-specific 2 [Homo sapiens]
Length = 313
Score = 342 bits (878), Expect = 5e-94
Identities = 170/299 (56%), Positives = 215/299 (71%), Gaps = 15/299 (5%)
Query: 24 RHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQ 83
R GPGL+++ QY +W+A RHEA LLPM+EDL++WL+ LLG ++ AE +E+LDNG LLCQ
Sbjct: 10 RSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQ 69
Query: 84 LIDVLQNMVKTCN--SEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETY 141
L + +Q K ++ + N P++K+PCK A SGSFFARDNTANFL WCRD+GVDET
Sbjct: 70 LAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLGVDETC 129
Query: 142 LFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTS-GPEDS 200
LFESEGLVLHK PR+V LCLLE+GRI +RYGVEPP L+KLEKEIE EETL S P S
Sbjct: 130 LFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPS 189
Query: 201 ISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVM 260
L +AVK I+EDPPC C ++F +E LS+GRYR+G+KILFIRMLH KHVM
Sbjct: 190 SKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFIRMLHNKHVM 249
Query: 261 VRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNP 319
VRVGGGW+T G+LLK+DPCR+LQ + ++ K Q +++P +MNP
Sbjct: 250 VRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQ------------SKSPTLKDMNP 296
>gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens]
Length = 880
Score = 183 bits (464), Expect = 5e-46
Identities = 142/408 (34%), Positives = 205/408 (50%), Gaps = 50/408 (12%)
Query: 44 EATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSE---ES 100
E L M+EDL+ WL L G+ + A L+ L+ G++LCQ +V+ + +E ++
Sbjct: 28 EQYLEAMKEDLAEWLRDLYGLDIDAANFLQVLETGLVLCQHANVVTDAALAFLAEAPAQA 87
Query: 101 GNFPMRKV--PCKKDAASGSFFARDNTANFLHWCR-DIGVDETYLFESEGLVLHKDPRQV 157
PM +V C A G+F ARDN +NF+ WCR ++G+ E +FE+E LVL K+ + V
Sbjct: 88 QKIPMPRVGVSCNGAAQPGTFQARDNVSNFIQWCRKEMGIQEVLMFETEDLVLRKNVKNV 147
Query: 158 YLCLLEIGRIVSRYGVEPPVLVKLEKEIELE---ETLLNTSGPEDSISIPKSCCRHEELH 214
LCLLE+GR R+GV P LV+LE+EIE E E L P + C L
Sbjct: 148 VLCLLELGRRAWRFGVAAPTLVQLEEEIEEEVRRELALPPPDPSPPAPPRRQPCHFRNLD 207
Query: 215 EAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDK--ILFIRMLHGKHVMVRVGGGWDTLQG 272
+ V+ + C+C +FS+ +SEG+YR+GD ++FIR+L HVMVRVGGGWDTL
Sbjct: 208 QMVQSLVSH--CTCPVQFSMVKVSEGKYRVGDSNTLIFIRILR-NHVMVRVGGGWDTLGH 264
Query: 273 FLLKYDPCRILQFATLEQKILAFQK----GVSNE-SVPDSPARTPQPPEMNPLSAVNMFQ 327
+L K+DPCR +L K +F K V +E V D P++T QP + + +
Sbjct: 265 YLDKHDPCRC---TSLSHKPGSFLKPPAPPVQHEVRVQDGPSQT-QP-------TMTISR 313
Query: 328 KQNSKPSVPVSIPKSKEKQGRPPGALVPASSL-KGGNLGS---------MSVRSKLPN-- 375
Q+ P V S +++ RPP P +G G+ RS +P+
Sbjct: 314 SQSPPPPVDWKTYTSSDRRLRPPTPSSPRPRRERGAGTGASREMAPFLRCQERSLIPSWR 373
Query: 376 SPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPR 423
P A P S T+K + P +S P P LPR
Sbjct: 374 QPTAGDSPPSPQSSS-TQKGRDPQCTSSGKREERYP-------PELPR 413
>gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo
sapiens]
Length = 681
Score = 166 bits (420), Expect = 7e-41
Identities = 179/656 (27%), Positives = 265/656 (40%), Gaps = 118/656 (17%)
Query: 44 EATLLPMQEDLSIWLSGL--LGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESG 101
EA + M+EDL+ WL+ L LG+ + L L G LCQ + + + +
Sbjct: 23 EAYVEAMKEDLAEWLNALYGLGLPGGGDGFLTGLATGTTLCQHANAVTEAARALAAAR-- 80
Query: 102 NFPMRKVPCKKDAA-SGSFFARDNTANFLHWCR-DIGVDETYLFESEGLVLHKDPRQVYL 159
P R V + + GSF ARDN A F+ WCR ++GV E +FE+E LVL K+ + V L
Sbjct: 81 --PARGVAFQAHSVVPGSFMARDNVATFIGWCRVELGVPEVLMFETEDLVLRKNEKSVVL 138
Query: 160 CLLEIGRIVSRYGVEPPVLVKLEKEIELE------------------ETLLNTSGPEDSI 201
CLLE+ R +R G+ P LV+ E+EIE E ET P
Sbjct: 139 CLLEVARRGARLGLLAPRLVQFEQEIERELRAAPPAPNAPAAGEDTTETAPAPGTPARGP 198
Query: 202 SIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDK--ILFIRMLHGKHV 259
+ S R+ L E V+ I C+C +F + +SEG+YR+GD ++F+R+L HV
Sbjct: 199 RMTPSDLRN--LDELVREIL--GRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLR-SHV 253
Query: 260 MVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNP 319
MVRVGGGWDTL+ +L K+DPCR S A P P +
Sbjct: 254 MVRVGGGWDTLEHYLDKHDPCRC-----------------------SSTAHRPPQPRVCT 290
Query: 320 LSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAA 379
S + + +P+ PV P S+ + RP V S K G R +LP
Sbjct: 291 FSPQRVSPTTSPRPASPV--PGSERRGSRPEMTPVSLRSTKEGPETPPRPRDQLP----- 343
Query: 380 SSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGK------------------NTSSPAL 421
HP+ + G +++S+S A P+G T +PA
Sbjct: 344 -PHPRSRRYSG--------DSDSSASSAQSGPLGTRSDDTGTGPRRERPSRRLTTGTPAS 394
Query: 422 PRTAPCISESPRKCISSPNTPKAKVIPAQNSADL--PESTLLPNKCSGKTQPKYLKHNHI 479
PR P + R + + + + P A L P S + Q L
Sbjct: 395 PRRPPALRSQSRDRL---DRGRPRGAPGGRGAQLSVPSPARRARSQSREEQAVLLVRRDR 451
Query: 480 SSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQS--SAKMTKTSSKTIATGLGTQS 537
+ + V S P+ P+A P P+ S S S ++ T + T L Q
Sbjct: 452 DGQHSWVPRGRGSGGSGRSTPQTPRARSPAAPRLSRVSSPSPELGTTPASIFRTPL--QL 509
Query: 538 QPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAF 597
P + + + L +A L SV+ P ++ D P SA+
Sbjct: 510 DPQQEQQLFRRLEEEFLANARALEAVASVTPTGPAPDPARAPD---------PPAPDSAY 560
Query: 598 QKTGPSSLKSPGRTPLSIV----SLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSG 649
+ SS + LS++ P S +T ++ A S S +G P G
Sbjct: 561 CSSSSSS------SSLSVLGGKCGQPGDSGRTANGLPGPRSQALSSSSDEGSPCPG 610
>gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo
sapiens]
Length = 681
Score = 166 bits (420), Expect = 7e-41
Identities = 179/656 (27%), Positives = 265/656 (40%), Gaps = 118/656 (17%)
Query: 44 EATLLPMQEDLSIWLSGL--LGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESG 101
EA + M+EDL+ WL+ L LG+ + L L G LCQ + + + +
Sbjct: 23 EAYVEAMKEDLAEWLNALYGLGLPGGGDGFLTGLATGTTLCQHANAVTEAARALAAAR-- 80
Query: 102 NFPMRKVPCKKDAA-SGSFFARDNTANFLHWCR-DIGVDETYLFESEGLVLHKDPRQVYL 159
P R V + + GSF ARDN A F+ WCR ++GV E +FE+E LVL K+ + V L
Sbjct: 81 --PARGVAFQAHSVVPGSFMARDNVATFIGWCRVELGVPEVLMFETEDLVLRKNEKSVVL 138
Query: 160 CLLEIGRIVSRYGVEPPVLVKLEKEIELE------------------ETLLNTSGPEDSI 201
CLLE+ R +R G+ P LV+ E+EIE E ET P
Sbjct: 139 CLLEVARRGARLGLLAPRLVQFEQEIERELRAAPPAPNAPAAGEDTTETAPAPGTPARGP 198
Query: 202 SIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDK--ILFIRMLHGKHV 259
+ S R+ L E V+ I C+C +F + +SEG+YR+GD ++F+R+L HV
Sbjct: 199 RMTPSDLRN--LDELVREIL--GRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLR-SHV 253
Query: 260 MVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNP 319
MVRVGGGWDTL+ +L K+DPCR S A P P +
Sbjct: 254 MVRVGGGWDTLEHYLDKHDPCRC-----------------------SSTAHRPPQPRVCT 290
Query: 320 LSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAA 379
S + + +P+ PV P S+ + RP V S K G R +LP
Sbjct: 291 FSPQRVSPTTSPRPASPV--PGSERRGSRPEMTPVSLRSTKEGPETPPRPRDQLP----- 343
Query: 380 SSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGK------------------NTSSPAL 421
HP+ + G +++S+S A P+G T +PA
Sbjct: 344 -PHPRSRRYSG--------DSDSSASSAQSGPLGTRSDDTGTGPRRERPSRRLTTGTPAS 394
Query: 422 PRTAPCISESPRKCISSPNTPKAKVIPAQNSADL--PESTLLPNKCSGKTQPKYLKHNHI 479
PR P + R + + + + P A L P S + Q L
Sbjct: 395 PRRPPALRSQSRDRL---DRGRPRGAPGGRGAQLSVPSPARRARSQSREEQAVLLVRRDR 451
Query: 480 SSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQS--SAKMTKTSSKTIATGLGTQS 537
+ + V S P+ P+A P P+ S S S ++ T + T L Q
Sbjct: 452 DGQHSWVPRGRGSGGSGRSTPQTPRARSPAAPRLSRVSSPSPELGTTPASIFRTPL--QL 509
Query: 538 QPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAF 597
P + + + L +A L SV+ P ++ D P SA+
Sbjct: 510 DPQQEQQLFRRLEEEFLANARALEAVASVTPTGPAPDPARAPD---------PPAPDSAY 560
Query: 598 QKTGPSSLKSPGRTPLSIV----SLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSG 649
+ SS + LS++ P S +T ++ A S S +G P G
Sbjct: 561 CSSSSSS------SSLSVLGGKCGQPGDSGRTANGLPGPRSQALSSSSDEGSPCPG 610
>gi|23065529 growth arrest-specific 2 like 1 isoform b [Homo
sapiens]
Length = 337
Score = 154 bits (389), Expect = 3e-37
Identities = 117/334 (35%), Positives = 167/334 (50%), Gaps = 47/334 (14%)
Query: 44 EATLLPMQEDLSIWLSGL--LGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESG 101
EA + M+EDL+ WL+ L LG+ + L L G LCQ + + + +
Sbjct: 23 EAYVEAMKEDLAEWLNALYGLGLPGGGDGFLTGLATGTTLCQHANAVTEAARALAAAR-- 80
Query: 102 NFPMRKVPCKKDAA-SGSFFARDNTANFLHWCR-DIGVDETYLFESEGLVLHKDPRQVYL 159
P R V + + GSF ARDN A F+ WCR ++GV E +FE+E LVL K+ + V L
Sbjct: 81 --PARGVAFQAHSVVPGSFMARDNVATFIGWCRVELGVPEVLMFETEDLVLRKNEKSVVL 138
Query: 160 CLLEIGRIVSRYGVEPPVLVKLEKEIELE------------------ETLLNTSGPEDSI 201
CLLE+ R +R G+ P LV+ E+EIE E ET P
Sbjct: 139 CLLEVARRGARLGLLAPRLVQFEQEIERELRAAPPAPNAPAAGEDTTETAPAPGTPARGP 198
Query: 202 SIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDK--ILFIRMLHGKHV 259
+ S R+ L E V+ I C+C +F + +SEG+YR+GD ++F+R+L HV
Sbjct: 199 RMTPSDLRN--LDELVREIL--GRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLR-SHV 253
Query: 260 MVRVGGGWDTLQGFLLKYDPCRILQFA--TLEQKILAFQKGVSNESVPDSPARTPQPPEM 317
MVRVGGGWDTL+ +L K+DPCR A + ++ F SP R
Sbjct: 254 MVRVGGGWDTLEHYLDKHDPCRCSSTAHRPPQPRVCTF-----------SPQRVSPTTSP 302
Query: 318 NPLSAVNMFQKQNSKPSV-PVSIPKSKEKQGRPP 350
P S V +++ S+P + PVS+ +KE PP
Sbjct: 303 RPASPVPGSERRGSRPEMTPVSLRSTKEGPETPP 336
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 74.3 bits (181), Expect = 3e-13
Identities = 81/383 (21%), Positives = 150/383 (39%), Gaps = 19/383 (4%)
Query: 307 SPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPAS---SLKGGN 363
S +RTPQ P ++ N+ +++ + PV+I S+ P +L A +L G N
Sbjct: 2325 SSSRTPQAP-----ASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGAN 2379
Query: 364 LGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPR 423
L S V + + P L P APS + +S + +P + +P+
Sbjct: 2380 LTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSL 2439
Query: 424 TAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRD 483
P + PR + S + +++ + AQ + +L + T + +S
Sbjct: 2440 LPPA-QDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA 2498
Query: 484 NAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGA 543
V H +S + P A ++P +SS+ + +SS + ++ + S S G+
Sbjct: 2499 PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS 2558
Query: 544 P----QAKPVPAQKLKSALNLNQPV-----SVSSVSPVKATQKSKDKNIVSATKKQPQNK 594
+ +P Q + + P +V P + T + + S++ +
Sbjct: 2559 SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSS 2618
Query: 595 SAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPAS 654
S+ + SS S + S S SS+ A Q + K S K PP + S
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA-SPKKPPPGERRSRS 2677
Query: 655 IRKPPSSVKDADSGDKKPTAKKK 677
RKP S++D+ S P +++
Sbjct: 2678 PRKPIDSLRDSRSLSYSPVERRR 2700
Score = 40.8 bits (94), Expect = 0.004
Identities = 84/386 (21%), Positives = 142/386 (36%), Gaps = 69/386 (17%)
Query: 370 RSKLPNSPAASSHPKLKSSKGITK----------KPQAPSNNASSSLASLNPVGKNTSSP 419
RS+ P + S + + +G ++ + + P+ + S S P + S
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRS-RSRTPARRGRSRS 694
Query: 420 ALPRTAPCISES-PRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNH 478
PR S S R+ S TP+ + +S +S + + P+ K
Sbjct: 695 RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754
Query: 479 ISSRDNAVSHLAAHSNS----------SSKCPKL---------------PKANIPVRPKP 513
S R ++S + + S SS CPK PKA P+
Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR 814
Query: 514 SFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVK 573
S SS+ K SKT + + S P P P Q ++ N+ SV+P +
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP-PRQGSITSPQANE----QSVTPQR 869
Query: 574 AT--QKSKDKNIVSATKKQ--------PQNKSAF-QKTGPSSLKSPGRTPLSIVSLPQ-- 620
+ + S D + S T + P+ KS+ + PS SP +I+S Q
Sbjct: 870 RSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRS 929
Query: 621 ---------SSTKTQTAPKSAQTVAK-SQHSTKGPPR----SGKTPASIRKPPSSVKDAD 666
S ++T P+ +++V+ S ++ PR +P + KP + + +
Sbjct: 930 HSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSH 989
Query: 667 SGDKKPTAKKKEDDDHYFVMTGSKKP 692
SG P K K ++GSK P
Sbjct: 990 SGSISPYPKVKAQTPPGPSLSGSKSP 1015
Score = 40.4 bits (93), Expect = 0.006
Identities = 72/377 (19%), Positives = 137/377 (36%), Gaps = 40/377 (10%)
Query: 296 QKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVP 355
+ G ++ P SP + P +P + +K+ S P P+ PP
Sbjct: 312 EPGTTSTQRPSSPETATKQPS-SPYEDKDKDKKEKSATR-PSPSPERSSTGPEPPAPTPL 369
Query: 356 ASSLKGGNLGSMSVR--SKLPNSPAASSHPKLKSS--KGITKKPQAPSNNASSSLASLNP 411
+ GG+ ++ S+ P +P + + P S K K PQ+ S+ +S
Sbjct: 370 LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK 429
Query: 412 VGKN-TSSPALPRTAPC------ISESP----------RKCISSPNTPKAKVIPAQNSAD 454
V ++ +SSP P+ AP IS SP ++ S +TP ++ +++ A
Sbjct: 430 VSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489
Query: 455 LPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPS 514
S P H+ S S A S + ++ P RP S
Sbjct: 490 AKRGR------SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWS 543
Query: 515 FQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKA 574
+S + S++ G P+ PA++ +S S +P +
Sbjct: 544 -RSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR----------SRTPARR 592
Query: 575 TQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQT 634
+S+ + + P + + P+ +S R+P+ S +S + +S
Sbjct: 593 RSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP 652
Query: 635 VAKSQHSTKGPPRSGKT 651
+ + ++ P R G++
Sbjct: 653 ARRGRSRSRTPARRGRS 669
Score = 39.3 bits (90), Expect = 0.012
Identities = 34/183 (18%), Positives = 68/183 (37%), Gaps = 3/183 (1%)
Query: 495 SSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKL 554
S S P+ + + K +S +K K S T + ++ + + P P +
Sbjct: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRR 259
Query: 555 KSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLS 614
S S S ++ + + + + P S + G + PG T
Sbjct: 260 AHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQ 319
Query: 615 IVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSS---VKDADSGDKK 671
S P+++TK ++P + K + S P S + ++ +PP+ + + G +
Sbjct: 320 RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQ 379
Query: 672 PTA 674
P A
Sbjct: 380 PLA 382
Score = 37.0 bits (84), Expect = 0.062
Identities = 89/423 (21%), Positives = 149/423 (35%), Gaps = 91/423 (21%)
Query: 291 KILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSI---------PK 341
+++ +K V+ ++P + P E + L+ +N + + + + +S P+
Sbjct: 95 RLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQ 154
Query: 342 SKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNN 401
+ ++ + P P L ++S P K K KK + +
Sbjct: 155 RRAREAKQPAPEPPKPY-------------SLVRESSSSRSPTPKQKKKKKKKDRGRRSE 201
Query: 402 ASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLL 461
+SS K +S R+ SES ++ SP TPK+K ST
Sbjct: 202 SSSPRRER----KKSSKKKKHRSE---SESKKRKHRSP-TPKSKRKSKDKKRKRSRSTT- 252
Query: 462 PNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVR-PKPSFQSSAK 520
PK + + +S D+A S + S S S K + R P P+ S +
Sbjct: 253 -------PAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPA---SGR 302
Query: 521 MTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKD 580
+ + G + +PS P A K S SP + K KD
Sbjct: 303 RGEGDAPFSEPGTTSTQRPSS------PETATKQPS-------------SPYE--DKDKD 341
Query: 581 KNIVSATKKQPQNKSAFQKTGPSS-------LKSPGRTPLSIVSLPQSS----------- 622
K SAT+ P + + TGP + G +P + + P S
Sbjct: 342 KKEKSATRPSPSPERS--STGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASP 399
Query: 623 TKTQTAPKSAQTVAKSQHSTKGPPRSGKTPAS--IRKPPSSVKDADSG------DKKPTA 674
T+ ++ PKS + + +S S PP T S P S K A + PT+
Sbjct: 400 TRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTS 459
Query: 675 KKK 677
K +
Sbjct: 460 KNR 462
Score = 33.9 bits (76), Expect = 0.52
Identities = 70/349 (20%), Positives = 134/349 (38%), Gaps = 56/349 (16%)
Query: 300 SNESVPDSPARTPQPPEMNPLSAVNMFQK--------------------QNSKPSVPVSI 339
S S PD+ + PP + +++ + K + SK S+ S
Sbjct: 970 SGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSC 1029
Query: 340 PKSKE-----KQGRPPGAL---VPASSLKGGNLGSMSVRSKLPNSPAASSH---PKLKS- 387
P S K PPG V + LKG + S RS + SH P L+S
Sbjct: 1030 PGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSK 1089
Query: 388 SKGITKKPQAPSNNASSSLASLNPV----GKNTSSPALPRTAPCISESPRKCISSPNTPK 443
S+ K ++ S++ + LAS +P+ G+ ++SP L + SS T
Sbjct: 1090 SQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVD 1149
Query: 444 AKVIPAQNSADLPES----TLLPNKCSGKTQPKYL-KHNHISSRDNAVSHLAAHSNSSSK 498
+ + Q+ + ES L P + + + P+ K + +D S L + +
Sbjct: 1150 SNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLV--FKDTLR 1207
Query: 499 CPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSAL 558
P ++ P+ Q+SA T + + + + +P+ +
Sbjct: 1208 TPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAG-------------QILS 1254
Query: 559 NLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKS 607
+L+ + S S +++ + +++ VS T Q Q++++ + S+ S
Sbjct: 1255 HLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMAS 1303
Score = 33.1 bits (74), Expect = 0.89
Identities = 83/381 (21%), Positives = 136/381 (35%), Gaps = 32/381 (8%)
Query: 310 RTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSK-----EKQGRPPGALVP--ASSLKGG 362
RTP P E + + ++QNS ++P S + EK P G ++ +S LK
Sbjct: 1207 RTP-PRERSGAGSSPETKEQNS--ALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEM 1263
Query: 363 NLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALP 422
+ + ++ PA S S+ + + PS +S +P K S+ L
Sbjct: 1264 STSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLR 1323
Query: 423 RTA---PCISESPRKCISSPNTP-KAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNH 478
+ P + + NT ++V N L + P+ + + H+
Sbjct: 1324 ENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSS 1383
Query: 479 ISSRDNAVSHLAAHSNSSSKCPKLPKA-NIPVRPKPSFQSSAKMTKTSSKTIATGLGTQS 537
+AV SN S P L P R + S SS +M +T + + S
Sbjct: 1384 SELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGS 1443
Query: 538 QPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAF 597
P G P++ S+S SP S P+ K+
Sbjct: 1444 SP--GLRDGSGTPSRH-----------SLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP 1490
Query: 598 QKTGPSSLKSPGRTPLSIVSL-PQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIR 656
Q P S +SP L+ L PQ + +TVA++ + RSG +
Sbjct: 1491 QTPRPRS-RSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS--RSGSSQELDV 1547
Query: 657 KPPSSVKDADSGDKKPTAKKK 677
KP +S ++ D P +K K
Sbjct: 1548 KPSASPQERSESDSSPDSKAK 1568
Score = 32.0 bits (71), Expect = 2.0
Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 52/389 (13%)
Query: 307 SPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGS 366
S +RT S + ++ S+ P +I ++ R L+P + + +
Sbjct: 1994 SRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAI----RRRSRSRTPLLPRKRSRSRSPLA 2049
Query: 367 MSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAP 426
+ RS+ A L S ++ A +++ S ++ P +N S P A
Sbjct: 2050 IRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVA- 2108
Query: 427 CISESPRKCISSPN---TPKAK-----VIPAQNSADLPESTLL---------PNKCSGKT 469
++ S C S P+ TP + ++ S+ P S L P
Sbjct: 2109 -LNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDH 2167
Query: 470 QPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVR--------PKPSFQSS--A 519
Q + NH SR A++ A ++ P + A + R P S +++ A
Sbjct: 2168 QRTSVPENHAQSRI-ALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAA 2226
Query: 520 KMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSA---LNLNQPVSVSSVSPVKA-- 574
+ A + S + P A + + +A +NL P + + S V
Sbjct: 2227 NLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLAD 2286
Query: 575 --TQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSA 632
T + N+ A + P +A TG TP + + P SS++T AP SA
Sbjct: 2287 PRTPTAPAVNLAGA--RTPAALAALSLTGSG-------TPPTAANYP-SSSRTPQAPASA 2336
Query: 633 QTVA-KSQHSTKGPPRSGKTPASIRKPPS 660
V +S H+T +G A+ P S
Sbjct: 2337 NLVGPRSAHATAPVNIAGSRTAAALAPAS 2365
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 73.2 bits (178), Expect = 8e-13
Identities = 76/271 (28%), Positives = 109/271 (40%), Gaps = 48/271 (17%)
Query: 215 EAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGD--KILFIRMLHGKHVMVRVGGGWDTLQG 272
E + +A+ C C+ RF +E + E +YR GD ++ +R+L VMVRVGGGW L
Sbjct: 5167 EVTRQVAQ---CKCAKRFQVEQIGENKYRFGDSQQLRLVRILRST-VMVRVGGGWMALDE 5222
Query: 273 FLLKYDPCRILQFATLE-QKILAFQKGVS----------NESVPDSPARTPQPPEMNPLS 321
FL+K DPCR +E ++ +G S S P S A +P +
Sbjct: 5223 FLVKNDPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQ 5282
Query: 322 AVNMFQKQNSKPSVPVS----IPKSKEKQGRP-PGALVPASSLKGGNLGSMSVRS----- 371
+ + S P+ P S IP S K RP P +SL G S S S
Sbjct: 5283 SNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKT 5342
Query: 372 ---------KLPNSPAASSHPKLKSSK--------GITKKPQAPSNNASSSLASLNPVGK 414
P S A S SS+ + + A S+ + SS A G+
Sbjct: 5343 NRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAG----GQ 5398
Query: 415 NTSSPALPRTAPCISESPRKCISSPNTPKAK 445
S L + + + S + +SP TP K
Sbjct: 5399 GNSRRGLNKPSKIPTMSKKTTTASPRTPGPK 5429
>gi|33188443 microfilament and actin filament cross-linker protein
isoform b [Homo sapiens]
Length = 5938
Score = 66.6 bits (161), Expect = 7e-11
Identities = 76/277 (27%), Positives = 109/277 (39%), Gaps = 54/277 (19%)
Query: 215 EAVKHIAEDPPCSCSHRFSIEYLSEGRYRL------GD--KILFIRMLHGKHVMVRVGGG 266
E + +A+ C C+ RF +E + E +YR GD ++ +R+L VMVRVGGG
Sbjct: 5669 EVTRQVAQ---CKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGGG 5724
Query: 267 WDTLQGFLLKYDPCRILQFATLE-QKILAFQKGVS----------NESVPDSPARTPQPP 315
W L FL+K DPCR +E ++ +G S S P S A +P
Sbjct: 5725 WMALDEFLVKNDPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRS 5784
Query: 316 EMNPLSAVNMFQKQNSKPSVPVS----IPKSKEKQGRP-PGALVPASSLKGGNLGSMSVR 370
+ + + S P+ P S IP S K RP P +SL G S S
Sbjct: 5785 SSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSSRTSLAGDTSNSSSPA 5844
Query: 371 S--------------KLPNSPAASSHPKLKSSK--------GITKKPQAPSNNASSSLAS 408
S P S A S SS+ + + A S+ + SS A
Sbjct: 5845 STGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAG 5904
Query: 409 LNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAK 445
G+ S L + + + S + +SP TP K
Sbjct: 5905 ----GQGNSRRGLNKPSKIPTMSKKTTTASPRTPGPK 5937
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 62.4 bits (150), Expect = 1e-09
Identities = 86/386 (22%), Positives = 123/386 (31%), Gaps = 29/386 (7%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASS 358
V N P TP P + LS + K+ P IP S +G P S
Sbjct: 890 VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949
Query: 359 LKGGNLGSMSVRSKLP---NSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKN 415
KGG + P P+ P S KG P A + A+ +P G
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP 1009
Query: 416 TS---SPALPRTAPCISESPRKC----ISSPNTPKAK--VIPAQNSADLPESTLLPNKCS 466
T +P P+ +P + P+ ++P +PK P A + LP+
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
Query: 467 GKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSF----QSSAKMT 522
G P LK S + S K +P A P PK A T
Sbjct: 1070 GPATPS-LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 523 KTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKN 582
++ G G + P GAP K L P + +P K
Sbjct: 1129 PAATPPSPKG-GLATPPPKGAPTTPAATPPSPKGGL-ATPPPKGAPTTPAATPPSPKGGL 1186
Query: 583 IVSATKKQPQNKSAFQKTGPSSLKSPG-----RTPLSIVSLPQSSTKTQTAPKSAQTVAK 637
+ K P +A + L +P TP + P+ T + + T A
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246
Query: 638 SQHSTKG-----PPRSGKTPASIRKP 658
+ S KG PP+ TP + P
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPP 1272
Score = 60.1 bits (144), Expect = 7e-09
Identities = 87/395 (22%), Positives = 144/395 (36%), Gaps = 37/395 (9%)
Query: 301 NESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKS-KEKQGRPP--GALVPAS 357
++ P+ TP P+ P ++ P+ P + P S K G PP GA P +
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATS-----PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337
Query: 358 SLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPV-GKNT 416
G+ ++ + P+S + P S +G T PS+ ++ +P G
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPS--SKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395
Query: 417 SSPALPRTAPCISE-SPRKCISSPNTPKAKVIPAQNSADLPESTLLP-NKCSGKTQPKYL 474
SP T+P + SP+K ++P T + P++ P T + K + PK
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455
Query: 475 KHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLG 534
S D L A + S K P PK + P ++ A + T+ +
Sbjct: 1456 PATPSSKGDPT---LPAVTPPSPKEPPAPK-QVATSSSPK-KAPATPAPMGAPTLPAVIP 1510
Query: 535 TQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSS----VSPVKATQKSKDKNIVSATKKQ 590
+ + P ++ P + L+ P +++ + P K + K+
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570
Query: 591 PQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSS------TKTQTAPKSAQT--VAKSQHST 642
P S+ + + P P TP + P T +PK A T
Sbjct: 1571 PATPSSKEASSP-----PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Query: 643 KGP--PRSGKTPASIRKPPSSVKDADSGDKKPTAK 675
KGP P TP S PSS+KD+ + T K
Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660
Score = 53.9 bits (128), Expect = 5e-07
Identities = 97/380 (25%), Positives = 139/380 (36%), Gaps = 35/380 (9%)
Query: 300 SNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKP--SVPVSIPKSKEKQGRPPGA-LVPA 356
S + P PA TP P+ +P A F K S P + P S S P GA PA
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSP--AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061
Query: 357 SSLKGGNLGSMSVRSKLPNSPAASSHPKLK------SSKGITKKPQAPSNNASSSLASLN 410
++L G + K +P A++ P K S KG P A + LA+
Sbjct: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Query: 411 PVGKNTSSPALPRT------APCISESPRKCISSPNTPKAKVI--PAQNSADLPESTLLP 462
G T+ A P + P +P ++P +PK + P + + P +T
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181
Query: 463 NKCSGKT-QPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKM 521
K T PK ++ + LA S + P P A P PK + +
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA--PTTPAAT-PPSPKGGLATPSPK 1238
Query: 522 TKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALN--LNQPVSVSSVSPVKATQKS- 578
++ AT + P+ P+ P P +L L P + +P T S
Sbjct: 1239 GAPTTPA-ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297
Query: 579 KDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKS 638
K S K P +A T PS SPG P P T +PK T+ +
Sbjct: 1298 KGGPATSPPKGAPTPPAA---TPPSPKGSPGTPPPK--GAPTPPAVTPPSPKGTPTLPAT 1352
Query: 639 QHSTKGPPRSGKTPASIRKP 658
S+KG P TP+S P
Sbjct: 1353 TPSSKGGP---TTPSSKEGP 1369
Score = 52.4 bits (124), Expect = 1e-06
Identities = 96/399 (24%), Positives = 128/399 (32%), Gaps = 61/399 (15%)
Query: 279 PCRILQFATLEQKILAFQ-----KGVSNESVPDSPARTPQPPEMNPLS--AVNMFQKQNS 331
P ++ + L + L+FQ ++ P SP P P + PLS V + K+
Sbjct: 827 PVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP 886
Query: 332 KPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGI 391
PSV V++P KE P PA S+ + S K +PA P S KG
Sbjct: 887 TPSV-VNLPFPKEGPATPAPKQAPALSM------TSSSPKKARATPAPKGIPASPSPKGA 939
Query: 392 TKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQN 451
P A + A+ +P T A P SP+ P TP K P
Sbjct: 940 PTPPAATPPSPKGGPATPSPKWAPTPPAATP-------PSPK---GGPATPSPKGAPTPP 989
Query: 452 SADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRP 511
+A P P S K P + P PK + P
Sbjct: 990 AATPPSPKGGPATPSPKGAP----------------------TPPAVTPPSPKGSPAATP 1027
Query: 512 KP---SFQSSAKMTKTSSKTIATGL--GTQSQPSDGAPQAKPVPA-QKLKSALNLNQPVS 565
P S +A AT L G + P+ P K PA LK A P +
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA---PTPPA 1084
Query: 566 VSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKT 625
+ SP K P + T P K TP + P+ T
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH--KGAPTTPAATPPSPKGGLAT 1142
Query: 626 QTAPKSAQTVAKSQHSTKG----PPRSGKTPASIRKPPS 660
+ T A + S KG PP G PPS
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181
Score = 46.6 bits (109), Expect = 8e-05
Identities = 88/401 (21%), Positives = 131/401 (32%), Gaps = 46/401 (11%)
Query: 307 SPARTPQPPEMNPLSAVNMFQKQNSK--PSVPVSIPKSKE-------KQGRPPGALVPAS 357
SP P PP P S K P+ P + P S + +G P
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157
Query: 358 SLKGGNLGSMSVRSKLPNSPAASS-HPK----LKSSKGITKKPQAPSNNASSSLASLNPV 412
S KGG L + + P +PAA+ PK S KG P A + LA+ +P
Sbjct: 1158 SPKGG-LATPPPKGA-PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 413 GKNTSSPALPRT------APCISESPRKCISSPNTPKA-KVIPAQNSADLPESTLLPNKC 465
G T+ A P + P +P ++P +PK P A P + P+
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275
Query: 466 SGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTS 525
G P H + + AV + PK A P + P+ ++ +
Sbjct: 1276 GGLATPP-----HKGAPNPAVV--------TPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322
Query: 526 SKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSV---SPVKATQKSKDKN 582
S G + P+ P K P + + P + SS +P AT K
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382
Query: 583 IVSATKKQ-------PQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTV 635
++ + P+ P S K TP++ S T P
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 636 AKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKK 676
K +T P TP+S P S + P K+
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
Score = 44.3 bits (103), Expect = 4e-04
Identities = 86/349 (24%), Positives = 128/349 (36%), Gaps = 45/349 (12%)
Query: 300 SNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSI---PKSKEKQGRPPGALVPA 356
S + P PA TP PE P + S P P S+ P S GA VP
Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPK-GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
Query: 357 SSLKG--GNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGK 414
+S KG G +++ L +PA S P + + K PQ ++A+S +P K
Sbjct: 1668 AS-KGLPAKKGPTALKEVLV-APAPESTPIITAPT--RKGPQTKKSSATSPPICPDPSAK 1723
Query: 415 NTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYL 474
N S L AP +P + ++ AK A +S P+ L P + T
Sbjct: 1724 NGSKGPLSTVAP----APLLPVQKDSSKTAKGKDASHS---PKGPLAPPESKASTPLTAA 1776
Query: 475 KHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSF--QSSAKMTKTSSKTIATG 532
+ + + S AA S S P P + PK F S + ++ SK +A
Sbjct: 1777 AFEKVLPKPESASVSAAPSPPVS-LPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA-- 1833
Query: 533 LGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQ 592
P+D +P + + V SV T KS + + + KQP
Sbjct: 1834 ------PADEDELLPLIPPEPISGG------VPFQSVLVNMPTPKSAGIPVPTPSAKQPV 1881
Query: 593 NKSAFQKTGPSSLKSPGRTPLSIVSLP--QSSTKTQTAPKSAQTVAKSQ 639
K+ K G S S+P + TQ + AQ A ++
Sbjct: 1882 TKNN---------KGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAE 1921
Score = 43.5 bits (101), Expect = 7e-04
Identities = 87/363 (23%), Positives = 130/363 (35%), Gaps = 54/363 (14%)
Query: 333 PSVPVSIPK-SKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAA-----SSHPKLK 386
P +P S+P S G PPG + K + S + + +SP S
Sbjct: 728 PEIPKSVPSPSLPPAGTPPG------TKKVDGISHTSALAPVASSPKECPTEDSGASATA 781
Query: 387 SSKG-ITKKPQAPS--NNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTP- 442
SSKG +T +PS + S P K ++ P ++P +SSP +P
Sbjct: 782 SSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP----------DTPIGNLSSPVSPV 831
Query: 443 KAKVIPA-----QNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSS 497
+A +P Q S D P +T P S K P +S + + + S
Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891
Query: 498 KCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSA 557
P PK P P P + MT +S K + P+ +P+ P P +A
Sbjct: 892 NLP-FPKEG-PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP----AA 945
Query: 558 LNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVS 617
+ ++ SP A +AT P K GP++ SP P +
Sbjct: 946 TPPSPKGGPATPSPKWAPTPP------AATPPSP-------KGGPAT-PSPKGAPTPPAA 991
Query: 618 LPQSST--KTQTAPKSAQTV-AKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTA 674
P S +PK A T A + S KG P + P PP++ + G T
Sbjct: 992 TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP 1051
Query: 675 KKK 677
K
Sbjct: 1052 LPK 1054
Score = 35.0 bits (79), Expect = 0.23
Identities = 77/368 (20%), Positives = 119/368 (32%), Gaps = 44/368 (11%)
Query: 291 KILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPP 350
K ++ + S P + P P N + + PSV P
Sbjct: 337 KTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPS 396
Query: 351 GALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLN 410
G+L A+S S+ ++S SP A+ H L + ++ P L N
Sbjct: 397 GSLNVATSFSLSPTTSLILKS----SPNATYHYPLVAQMPVSSVGTTP-------LVVTN 445
Query: 411 PVGKNTSSPALPRTAPCISE-------------SPRKCISSPNTPKAKVIPAQNSADLPE 457
P + A C+S SP + +P PK + +P
Sbjct: 446 PCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPV 505
Query: 458 STLLPNKCSGKTQPKYLKHNHISSRD---------NAVSHLAAHSNSSSKCPK-LPKANI 507
S LP+ K P + + +D A A ++ K P LP
Sbjct: 506 SPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQA 565
Query: 508 PVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSV- 566
+ PSFQS T +S + + T ++ S G P PA + S L +N SV
Sbjct: 566 APKNSPSFQS----TSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVI 621
Query: 567 ---SSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSST 623
S P A K I P + P++ K G + + + P
Sbjct: 622 KTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAK--GTSTYTTTASPFLEG 679
Query: 624 KTQTAPKS 631
APK+
Sbjct: 680 TVSLAPKN 687
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 60.8 bits (146), Expect = 4e-09
Identities = 88/435 (20%), Positives = 166/435 (38%), Gaps = 66/435 (15%)
Query: 289 EQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVS--IPKSKEKQ 346
E+ I + VS +P A T +++ + + + +S P+ P S IPKS +
Sbjct: 154 EESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSE 213
Query: 347 GRPPGALVPASSLKGGNLGSMS-------------VRSKLPNSPAASSHPKLKSSKG--- 390
G P +PAS++K + +++ + ++ +SP + P L +S
Sbjct: 214 GSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGG 273
Query: 391 ---ITKKPQAPSNNASSSLASLNPVGKNTSSPALPRT----APCISES---PRKCISSPN 440
+T+ P + SS ++L+ T+ P + T +P +E P + +
Sbjct: 274 STPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGS 333
Query: 441 TP----KAKVIPAQNS-------ADLPESTLL-----PNKCSGKTQPKYLKHNHISSRDN 484
TP A +P S + STL+ P+ + + + +S
Sbjct: 334 TPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGST 393
Query: 485 AVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAP 544
++++ + + + IPV K ++++ + + + T + T S PS+G+
Sbjct: 394 PLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIAT-STPSEGST 452
Query: 545 QAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSS 604
+P PV+ S S + T + ++T+ +A + P+S
Sbjct: 453 PLTSMPVS--------TTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTS 504
Query: 605 LKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHST-KGPPRSGKTPASIRKPPSSVK 663
S G TPL+ +S+ S VA S+ ST P TP + SS
Sbjct: 505 TPSEGSTPLTSMSV------------STMPVASSEASTLSTTPVDTSTPVTTSSEASSSS 552
Query: 664 DADSGDKKPTAKKKE 678
G PT+ E
Sbjct: 553 TTPEGTSIPTSTPSE 567
Score = 59.7 bits (143), Expect = 9e-09
Identities = 81/373 (21%), Positives = 139/373 (37%), Gaps = 57/373 (15%)
Query: 305 PDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNL 364
P++ + P + N + + P+ S+P S +GR P +P S+ L
Sbjct: 821 PEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVST----TL 876
Query: 365 GSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALP-R 423
+ S S L +P +S P S T+ +P+ + +S+ + P +T ++P
Sbjct: 877 VATSAISTLSTTPVDTSTPVTNS----TEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDS 932
Query: 424 TAPCISESPRKCISSP---NTPKAKVIPAQNSADLPESTLLPNKCSGK-TQPKYLKHNHI 479
T P +S R ++P +TP A +S E T +P + T P
Sbjct: 933 TTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPL------- 985
Query: 480 SSRDNAVSH-LAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQ 538
VSH L A+S +S+ +N P+ S + +S +T
Sbjct: 986 --TSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTST------- 1036
Query: 539 PSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQ 598
PS+G+ +P V+ S S + T + + ++ + +A
Sbjct: 1037 PSEGSTPLTRMPVSTTM--------VASSETSTLSTTPADTSTPVTTYSQASSSSTTADG 1088
Query: 599 KTGPSSLKSPGRTPLSIVSLP-------QSST------------KTQTAPKSAQTVAKSQ 639
+ P+S S G TPL+ V + ++ST T T S+ T A+
Sbjct: 1089 TSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGT 1148
Query: 640 HSTKGPPRSGKTP 652
PP G TP
Sbjct: 1149 SIPTSPPSEGTTP 1161
Score = 58.5 bits (140), Expect = 2e-08
Identities = 93/424 (21%), Positives = 160/424 (37%), Gaps = 65/424 (15%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRPPGALVPA 356
VS +V S T + V + + +S P+ S+P S ++GRPP +P
Sbjct: 1874 VSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPV 1933
Query: 357 S--SLKGGNLGSMSV--------------RSKLPNSPAASSHPKLKSSKG---ITKKPQA 397
S ++ + ++S S P + +S P S+G +T P +
Sbjct: 1934 STTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLS 1993
Query: 398 PSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCIS-SPNTPKAKVIPAQNSADLP 456
+ SS ++L+ +TS+PA T S + S +TP + P A +P
Sbjct: 1994 TTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPL---AGMP 2050
Query: 457 ESTLLPNKCSGKT------QPKYLKHNHISSRDNAVSH-----LAAHSNSSSKCPKLPKA 505
ST L G T K N + +A + ++A S S +P +
Sbjct: 2051 VSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLS 2110
Query: 506 NIPV-RPKPSFQSSAKM---------TKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLK 555
PV P+ S S+ + T+ SS I T GT Q S + + P+ + +
Sbjct: 2111 TTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTE-GTSMQTSTYSDRRTPLTSMPVS 2169
Query: 556 SALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSI 615
+ + + +S S +PV + + ++T+ + ++ + P+S S G TP +
Sbjct: 2170 TTVVASSAISTLSTTPVDTSTP-----VTNSTEARSSPTTSEGTSMPTSTPSEGSTPFT- 2223
Query: 616 VSLPQSSTKTQTAPKSAQTVAKSQHST-KGPPRSGKTPASIRKPPSSVKDADSGDKKPTA 674
+ P S V S+ ST P TP + +S G PT+
Sbjct: 2224 -----------SMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTS 2272
Query: 675 KKKE 678
E
Sbjct: 2273 TLSE 2276
Score = 57.4 bits (137), Expect = 4e-08
Identities = 83/375 (22%), Positives = 136/375 (36%), Gaps = 33/375 (8%)
Query: 303 SVPDS-PARTPQPPEMNPLSAVNMFQKQNSK-------PSVPVSIPKSKEKQGRPPGALV 354
S+P S P+ P P+S + + ++S S PV+ G +
Sbjct: 3153 SMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSI 3212
Query: 355 PASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGI-TKKPQAPSNNASSSLASLNPVG 413
P S+ G SV + N+P ASS + S+ + + P S ASSS +
Sbjct: 3213 PTSTPSEGMTPLTSV--PVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTS 3270
Query: 414 KNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLP---ESTLLPNKCSGKTQ 470
TS+P+ T ++S T PA S + +++ P G +
Sbjct: 3271 MPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSM 3330
Query: 471 PKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTS-SKTI 529
P S+ + L S S++ + + P + T+ S S T
Sbjct: 3331 PT-------STYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTT 3383
Query: 530 ATGLGTQ-SQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATK 588
A G S PS+G +P PV S V+ + T + + ++T+
Sbjct: 3384 AEGTSIPTSSPSEGTTPLASMPVS--------TTPVVSSEVNTLSTTPVDSNTLVTTSTE 3435
Query: 589 KQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQH--STKGPP 646
A + P+S S G TPLSI+ L + + A + T + +T P
Sbjct: 3436 ASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPT 3495
Query: 647 RSGKTPASIRKPPSS 661
S T A + P+S
Sbjct: 3496 NSSPTTAEVTSMPTS 3510
Score = 57.0 bits (136), Expect = 6e-08
Identities = 92/423 (21%), Positives = 157/423 (37%), Gaps = 63/423 (14%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRPPGALVPA 356
VS V S A T ++ + + S P+ +SIP S +G+ P +P
Sbjct: 1403 VSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPV 1462
Query: 357 SSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNT 416
S+ N S S L +P S+ P + S T +P+ +S+A P +T
Sbjct: 1463 SNTPVAN----SEASTLSTTPVDSNSPVVTS----TAVSSSPTPAEGTSIAISTPSEGST 1514
Query: 417 SSPALP--------------RTAPCISESP----RKCISSPNTPKAKVIPAQNSAD---- 454
+ ++P T P ++ +P + SSP T + ++
Sbjct: 1515 ALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTP 1574
Query: 455 ---LPESTLLPNKCSGKT---QPKYLKHNHISSRDNAVSHLAAHSNSSSKCPK------- 501
LP ST+L T P K +S + + S A S+ + P
Sbjct: 1575 LTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLT 1634
Query: 502 -LPKANIPVR-PKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQ---KLKS 556
+P + PV P+ S S+ + S +T + + P++G + L S
Sbjct: 1635 SIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTS 1694
Query: 557 ALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIV 616
PV+ S++S + T + ++T+ + ++ + P+S S G TPL+
Sbjct: 1695 ITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLT-- 1752
Query: 617 SLPQSSTKTQTAPKSAQTVAKSQHST-KGPPRSGKTPASIRKPPSSVKDADSGDKKPTAK 675
S+P S+T V S+ ST P TP + +S G PT+
Sbjct: 1753 SIPVSTT----------PVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTST 1802
Query: 676 KKE 678
E
Sbjct: 1803 LSE 1805
Score = 55.1 bits (131), Expect = 2e-07
Identities = 95/405 (23%), Positives = 151/405 (37%), Gaps = 41/405 (10%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRPPGALVPA 356
VS V S A T ++ + V + S P+ SIP S +G P +P
Sbjct: 2227 VSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPV 2286
Query: 357 SSLKGGN-----LGSMSVRSKLP-------NSPA----ASSHPKLKSSKG---ITKKPQA 397
S N L + V S P +SP +S P SS+G +T+ P +
Sbjct: 2287 SHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVS 2346
Query: 398 PSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPE 457
+ AS ++L+ +TS+P + S + S P + ++ S +
Sbjct: 2347 TTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVST 2406
Query: 458 STLLPNKCSG-KTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPK----LPKANIPVRPK 512
++ ++ S T P +S + + S A S P P A++PV
Sbjct: 2407 MPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT 2466
Query: 513 PSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAK----PVPAQKLKSALNLNQPVSVSS 568
P S A T+ +T + T ++ S A+ P+ S L + PVS +
Sbjct: 2467 PVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTP 2526
Query: 569 VSPVKATQKSK---DKN--IVSATKKQPQNKSAFQKTGPSSLKSPGRTPL-----SIVSL 618
V+ +A+ S D N +V++T+ SA + P+S S G TPL S L
Sbjct: 2527 VASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586
Query: 619 PQSSTKT-QTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSV 662
S T T P + T P + K + PS V
Sbjct: 2587 ASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEV 2631
Score = 49.7 bits (117), Expect = 9e-06
Identities = 82/413 (19%), Positives = 153/413 (37%), Gaps = 51/413 (12%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRP-----PG 351
V++ V S A T ++ + V K +S P+ + +P S +G P
Sbjct: 2817 VNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPV 2876
Query: 352 ALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSN----------- 400
+ P +S + L + V + +P + + +++G + PS
Sbjct: 2877 STTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVS 2936
Query: 401 -----NASSSLASLNPVGKNT--SSPALPRTAPCISESPRKCISSPN---TPKAKVIPAQ 450
+ +S S PV T ++ A ++P +E IS+P TP + +
Sbjct: 2937 TVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVST 2996
Query: 451 NSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSH---LAAHSNSSSKCPKLPKANI 507
E++ L + + P SS A ++ S S+ +P +
Sbjct: 2997 MPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTT 3056
Query: 508 PVR-PKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSV 566
PV P+ S S+ + S +T + + P++G + P+ S PVS
Sbjct: 3057 PVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGT--SMPISTYSEGSTPLTGVPVST 3114
Query: 567 -----SSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLS------- 614
S++S + T + ++T+ ++ + P+S S G TPL+
Sbjct: 3115 TPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTM 3174
Query: 615 IVSLPQSSTKTQT-----APKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSV 662
+V + ST + T P + T A S + +G TP+ P +SV
Sbjct: 3175 LVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSV 3227
Score = 49.3 bits (116), Expect = 1e-05
Identities = 84/393 (21%), Positives = 143/393 (36%), Gaps = 61/393 (15%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRP-----PG 351
VS + S A T ++ + + + + P+ S+P S +G P P
Sbjct: 754 VSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPV 813
Query: 352 ALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNP 411
++ P +S + L + V S NSP +S T+ +P+ +S+ +
Sbjct: 814 SITPVTSPEASTLSTTPVDS---NSPVTTS----------TEVSSSPTPAEGTSMPTSTY 860
Query: 412 VGKNTSSPALPRTAPCISESPRKCISSP----NTPKAKVIPAQNSADLPESTLLPNKCSG 467
T ++P + ++ S +S+ +TP A++S E T +P G
Sbjct: 861 SEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPG 920
Query: 468 KTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSK 527
+ S D+ +++ + + S P + PV + TSS
Sbjct: 921 EGSTPLT-----SMPDSTTPVVSSEARTLSATPV--DTSTPV--------TTSTEATSSP 965
Query: 528 TIATGLGTQ-SQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSA 586
T A G S PS+G P+ + + L N S S +PV + + ++
Sbjct: 966 TTAEGTSIPTSTPSEGTT---PLTSTPVSHTLVANSEASTLSTTPVDSNTP-----LTTS 1017
Query: 587 TKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHST-KGP 645
T+ +A + P+S S G TPL+ P S VA S+ ST
Sbjct: 1018 TEASSPPPTAEGTSMPTSTPSEGSTPLT------------RMPVSTTMVASSETSTLSTT 1065
Query: 646 PRSGKTPASIRKPPSSVKDADSGDKKPTAKKKE 678
P TP + SS G PT+ E
Sbjct: 1066 PADTSTPVTTYSQASSSSTTADGTSMPTSTYSE 1098
Score = 48.9 bits (115), Expect = 2e-05
Identities = 86/402 (21%), Positives = 144/402 (35%), Gaps = 44/402 (10%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRPPGALVPA 356
V + V S A T ++ + V + +S P+ S+P S +G +P
Sbjct: 1226 VRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPV 1285
Query: 357 SSL-----------------KGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPS 399
S+ KG + S V S P +S P S+G T P
Sbjct: 1286 STTLVTSPEASTLLTTPVDTKGPVVTSNEVSSS-PTPAEGTSMPTSTYSEGRTPLTSIPV 1344
Query: 400 NN---ASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPN-------TPKAKVIPA 449
N ASS+++ L+ + S+P T C S + + S PN TP + +
Sbjct: 1345 NTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVS 1404
Query: 450 QNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVS-HLAAHSNSSSKCP--KLPKAN 506
E++ L + P SS A + + S K P +P +N
Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN 1464
Query: 507 IPV-RPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVS 565
PV + S S+ + S +T + + P++G A P++ + ++ PVS
Sbjct: 1465 TPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSI--PVS 1522
Query: 566 VSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKT 625
++V+ S + N +S T SS + T + + + ST
Sbjct: 1523 TTTVA-------SSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPL 1575
Query: 626 QTAPKSAQTVAKSQHST-KGPPRSGKTPASIRKPPSSVKDAD 666
+ P S V S+ +T P KT + SS A+
Sbjct: 1576 TSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAE 1617
Score = 47.4 bits (111), Expect = 5e-05
Identities = 79/350 (22%), Positives = 134/350 (38%), Gaps = 38/350 (10%)
Query: 351 GALVPAS--SLKGGNLGSMSVRSKLPNSPAAS--SHPKLKSSKGITKKPQAPSNNASSSL 406
G +P S S +G + SMSV + L S AS S + S+ +T +A S++ ++
Sbjct: 616 GTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG 675
Query: 407 ASLNPVGKNT--SSP--ALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLP 462
S+ P T S+P ++P ++ S +S+ TP P S + S P
Sbjct: 676 TSM-PTSTYTEGSTPLTSMPVNTTLVASSEASTLST--TPVDTSTPVTTSTEASSS---P 729
Query: 463 NKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMT 522
G + P S ++ + + + P+ +S + +
Sbjct: 730 TTADGASMPTSTP----SEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEAS 785
Query: 523 KTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKN 582
+ + T T + S PS+G+P +P PV+ S + T +
Sbjct: 786 CSPTTTEGTSMPI-STPSEGSPLLTSIPVSIT--------PVTSPEASTLSTTPVDSNSP 836
Query: 583 IVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHST 642
+ ++T+ A + P+S S GRTPL+ S+P S+T T+ S + ST
Sbjct: 837 VTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLT--SMPVSTTLVATSAISTLSTTPVDTST 894
Query: 643 KGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKEDDDHYFVMTGSKKP 692
P + T A R P++ G PT+ E M S P
Sbjct: 895 ---PVTNSTEA--RSSPTT----SEGTSMPTSTPGEGSTPLTSMPDSTTP 935
Score = 46.2 bits (108), Expect = 1e-04
Identities = 77/373 (20%), Positives = 137/373 (36%), Gaps = 41/373 (10%)
Query: 319 PLSAVNMFQKQNSKPS---VPVSIPKSKEKQGRPPGALVPASSLKGGN-------LGSMS 368
PLS + + S S V S P + +G +S++ L M
Sbjct: 1991 PLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMP 2050
Query: 369 VRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPCI 428
V + L SS S+ + K Q ++ +SS A+ S+P+ +P +
Sbjct: 2051 VSTTL----VVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPS--EGSPLL 2104
Query: 429 SESPRKC--ISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAV 486
+ P ++SP P +++ + ST + + T+ ++ + S R +
Sbjct: 2105 TSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPI-PTEGTSMQTSTYSDRRTPL 2163
Query: 487 SHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQA 546
+ + + + + PV +S + + + + T + T S PS+G+
Sbjct: 2164 TSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT-STPSEGSTPF 2222
Query: 547 KPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLK 606
+P + PV S S + AT + ++T+ +A + P+S
Sbjct: 2223 TSMPVSTM--------PVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTL 2274
Query: 607 SPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHST-KGPPRSGKTPASIRKPPSSVKDA 665
S G TPL+ S+P S T VA S+ ST P TP + SS
Sbjct: 2275 SEGTTPLT--SIPVSHT----------LVANSEVSTLSTTPVDSNTPFTTSTEASSPPPT 2322
Query: 666 DSGDKKPTAKKKE 678
G PT+ E
Sbjct: 2323 AEGTSMPTSTSSE 2335
Score = 45.8 bits (107), Expect = 1e-04
Identities = 83/388 (21%), Positives = 143/388 (36%), Gaps = 41/388 (10%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRPPGALVPA 356
+S V S A T ++ + V NS P+ S+P S +G P +P
Sbjct: 3465 LSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPV 3524
Query: 357 S-----SLKGGNLGSMSVRSK--LPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASL 409
S S + L + V S + +S ASS P + + T + PS +SS L
Sbjct: 3525 STTPVASSEASTLSTTPVDSNTFVTSSSQASSSPA--TLQVTTMRMSTPSEGSSSLTTML 3582
Query: 410 NPVGKNTSSPALPRTAPCISES-----PRKCISSPNTPKAKVIPAQNSADLPESTLLPNK 464
TSS A + P + S + S+P P+ +P +++ ST L
Sbjct: 3583 LSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEV--STPLTIM 3640
Query: 465 CSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLP-----------KANIPVRPKP 513
T + S+ S S S P P + + P+ P
Sbjct: 3641 PVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMP 3700
Query: 514 SFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVS------ 567
S+ ++T + T++T S P + +A A + ++++ P+ +S
Sbjct: 3701 --VSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTI 3758
Query: 568 --SVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKT 625
S +PV +S +I S ++ + P++L+ P+S S +S+ T
Sbjct: 3759 LVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTS-ERSTLLT 3817
Query: 626 QTAPKSAQTVAKSQHST-KGPPRSGKTP 652
++ S+ ST PP TP
Sbjct: 3818 TVLISPISVMSPSEASTLSTPPGDTSTP 3845
Score = 45.1 bits (105), Expect = 2e-04
Identities = 83/390 (21%), Positives = 137/390 (35%), Gaps = 55/390 (14%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRPPGALVPA 356
V+ V S A T ++ + V + +S P+ S+P S +G P +P
Sbjct: 695 VNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPV 754
Query: 357 SSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNT 416
S L + S S L +P L +S IT +A + ++ S+ +
Sbjct: 755 SK----TLLTSSEASTLSTTP-------LDTSTHITTSTEASCSPTTTEGTSMPISTPSE 803
Query: 417 SSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLL---PNKCSGKTQPKY 473
SP L T+ +S +P ++SP P +++ + ST + P G + P
Sbjct: 804 GSPLL--TSIPVSITP---VTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPT- 857
Query: 474 LKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSK-TIATG 532
+ +S + +P + V S TS+ T +T
Sbjct: 858 ----------------STYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTE 901
Query: 533 LGTQSQPSDGAPQAKPVPAQ---KLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKK 589
+ S+G P + L S + PV S + AT + ++T+
Sbjct: 902 ARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEA 961
Query: 590 QPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHST-KGPPRS 648
+A + P+S S G TPL+ + P S VA S+ ST P
Sbjct: 962 TSSPTTAEGTSIPTSTPSEGTTPLT------------STPVSHTLVANSEASTLSTTPVD 1009
Query: 649 GKTPASIRKPPSSVKDADSGDKKPTAKKKE 678
TP + SS G PT+ E
Sbjct: 1010 SNTPLTTSTEASSPPPTAEGTSMPTSTPSE 1039
Score = 44.3 bits (103), Expect = 4e-04
Identities = 76/351 (21%), Positives = 126/351 (35%), Gaps = 50/351 (14%)
Query: 305 PDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPAS-----SL 359
P++ + P + N + ++ + S+P S +G P +P S S
Sbjct: 2530 PEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASS 2589
Query: 360 KGGNLGSMSVRSKLP---NSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNT 416
+ L + V + +P ++ +SS K + P S + +S L S PV +
Sbjct: 2590 EASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSE 2649
Query: 417 SSP--ALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYL 474
+S P + + SSP T + +P + ST L N T
Sbjct: 2650 ASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGE--RSTPLTNILVSTT----- 2702
Query: 475 KHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLG 534
L A+S +S+ + PV SS + +S I+T
Sbjct: 2703 --------------LLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRIST--- 2745
Query: 535 TQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNK 594
PSDG+ L S L PV+ S S V T + ++T+
Sbjct: 2746 ----PSDGSTP--------LTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPT 2793
Query: 595 SAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGP 645
+A + P+S S TPL+ S+P + T A A T++ + T P
Sbjct: 2794 TAEVTSMPTSTPSETSTPLT--SMPVN--HTPVASSEAGTLSTTPVDTSTP 2840
Score = 43.9 bits (102), Expect = 5e-04
Identities = 76/343 (22%), Positives = 127/343 (37%), Gaps = 45/343 (13%)
Query: 334 SVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNS-PAASSHPKLKSSKGI- 391
S PV+ S E P A + + + GS + S L ++ P ASS S+ +
Sbjct: 2720 STPVTT--SAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVD 2777
Query: 392 TKKPQAPSNNASSSLASLNPVGKNTSSPA---LPRTAPCISESPRKCISSPNTPKAKVIP 448
T P S ASSS + TS+P+ P T+ ++ +P ++S P
Sbjct: 2778 TSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTP---VASSEAGTLSTTP 2834
Query: 449 AQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIP 508
S + ST + P ++ + V ++ S S+ +P + P
Sbjct: 2835 VDTSTPVTTST------KASSSP--------TTAEGIVVPISTASEGSTLLTSIPVSTTP 2880
Query: 509 VRPKPSFQSSAKMTKTSSKTIATGLGTQSQPS-DGAPQAKPVPAQ---KLKSALNLNQPV 564
V + S TS + G+ S + +G P++ L S L PV
Sbjct: 2881 VASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPV 2940
Query: 565 SVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTK 624
+ S S + T + ++ + +A + P S RTPL+ +S+
Sbjct: 2941 AGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSV------ 2994
Query: 625 TQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADS 667
S VA S+ ST +TPA P ++ +A S
Sbjct: 2995 ------STMPVASSEASTLS-----RTPADTSTPVTTSTEASS 3026
Score = 43.9 bits (102), Expect = 5e-04
Identities = 81/375 (21%), Positives = 132/375 (35%), Gaps = 45/375 (12%)
Query: 338 SIPKSKEKQGRPPGALVPAS-----SLKGGNLGSMSVRSKLP--NSPAASSHPKL----- 385
SIP S +G P VP S S + L + V S P S ASS P
Sbjct: 3211 SIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTS 3270
Query: 386 -------KSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALP----RTAPCISES--- 431
+ S +T P + + ASS ++L+ +TS+P ++P I++
Sbjct: 3271 MPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSM 3330
Query: 432 PRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAA 491
P S +TP + + E++ L T P +S + ++S A
Sbjct: 3331 PTSTYSEGSTPLTNMSFSTTPVVSSEASTL------STTPVDTSTPVTTSTEASLSPTTA 3384
Query: 492 HSNS----SSKCPKLPKANIPVRPKPSFQSSAKMTKT----SSKTIATGLGTQSQPSDGA 543
S S P A++PV P S T S+ + T S P+
Sbjct: 3385 EGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAE 3444
Query: 544 PQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSA--TKKQPQNKS---AFQ 598
+ P S P+S + V+ +A+ S S T P N S A
Sbjct: 3445 GTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEV 3504
Query: 599 KTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKP 658
+ P+S G TPL+ + + + + A + T S ++ +PA+++
Sbjct: 3505 TSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVT 3564
Query: 659 PSSVKDADSGDKKPT 673
+ G T
Sbjct: 3565 TMRMSTPSEGSSSLT 3579
Score = 43.5 bits (101), Expect = 7e-04
Identities = 88/423 (20%), Positives = 147/423 (34%), Gaps = 79/423 (18%)
Query: 303 SVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRPPGALVPASSL- 359
S+ +PA T P V + + +S P+ S+ S +G P +P S++
Sbjct: 1533 SLSTTPAVTSTP--------VTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTML 1584
Query: 360 ----KGGNLGSMSVRSKLP---NSPAASSHPKLKSSKGI----------TKKPQAPSNNA 402
+ L + + SK ++ A+SS SS I T P + + A
Sbjct: 1585 VVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVA 1644
Query: 403 SSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPN-------TPKAKVI----PAQN 451
S ++L+ +++SP + T S +P + S P TP + P +
Sbjct: 1645 SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVAS 1704
Query: 452 SADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRP 511
SA ST + + T + + +S ++ NS+ P +IPV
Sbjct: 1705 SAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMP------NSTPSEGTTPLTSIPVST 1758
Query: 512 KPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAK--------------PVPAQKLKSA 557
P S A + +T + T ++ + A+ P+ + +
Sbjct: 1759 TPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHT 1818
Query: 558 LNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVS 617
L N S S +PV + N T SS +P S
Sbjct: 1819 LVANSEASTLSTTPVDS------------------NSPVVTSTAVSSSPTPAEGTSIATS 1860
Query: 618 LP-QSSTKTQTAPKSAQTVAKSQHST-KGPPRSGKTPASIRKPPSSVKDADSGDKKPTAK 675
P + ST + P S TVA S+ +T P TP + SS G PT+
Sbjct: 1861 TPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTST 1920
Query: 676 KKE 678
+E
Sbjct: 1921 PRE 1923
Score = 42.7 bits (99), Expect = 0.001
Identities = 61/311 (19%), Positives = 116/311 (37%), Gaps = 39/311 (12%)
Query: 371 SKLPNSPAASSHPKLKSSKGITKKPQAPSNN-----ASSSLASLNPVGKNT--SSPALPR 423
S P + +S P ++G T P++ + S S+ PV +T ++ P
Sbjct: 313 SSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPS 372
Query: 424 TAPCISESPRKCISS--------PNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLK 475
+ P +E+ S+ N P + ++ A + A ST+ + + T
Sbjct: 373 SLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTT-STIPVDSKTFVTTASEAS 431
Query: 476 HNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGT 535
+ ++ D +++ S+ P ++PV P S A T+ T + T
Sbjct: 432 SSPTTAEDTSIATSTPSEGST------PLTSMPVSTTPVASSEASNLSTTPVDSKTQVTT 485
Query: 536 QSQPSDGAPQAK------PVPAQ---KLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSA 586
++ S P A+ P++ L S PV+ S S + T + ++
Sbjct: 486 STEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTS 545
Query: 587 TKKQPQNKSAFQKTGPSSLKSPGRTPLS--------IVSLPQSSTKTQTAPKSAQTVAKS 638
++ + + + P+S S G TPL+ +VS S+T T A + S
Sbjct: 546 SEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSS 605
Query: 639 QHSTKGPPRSG 649
+ S+ G
Sbjct: 606 EASSSSTTAEG 616
Score = 38.9 bits (89), Expect = 0.016
Identities = 89/425 (20%), Positives = 154/425 (36%), Gaps = 70/425 (16%)
Query: 299 VSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVP--VSIPKSKEKQGRPPGALVPA 356
VS SV S A T ++ + V + +S P P ++P +G P +P
Sbjct: 3642 VSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPV 3701
Query: 357 S-----SLKGGNLGSMSVRSKLP---NSPAASSHPKLKSSKGITKKPQAPSNNASSSLAS 408
S S +G L + SV + P ++ A SS L S+ P S ++ L S
Sbjct: 3702 STTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVS 3761
Query: 409 LNPVGK--NTSSPALPRTAPCIS-ESPRKCISSPNT------------------------ 441
PV + +S+P++P +S + + SSP T
Sbjct: 3762 TTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLI 3821
Query: 442 -PKAKVIPAQNSA------DLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSN 494
P + + P++ S D L K + P + IS + L
Sbjct: 3822 SPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLV 3881
Query: 495 SSSKCPKLPKANI----PVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVP 550
S++ P A+I P+ +F S T + +AT + P
Sbjct: 3882 STTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGT---- 3937
Query: 551 AQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATK-KQPQNKSAFQKTGPSSLK--- 606
+ + PV+ S+ AT + ++++T+ P S+ T S+ K
Sbjct: 3938 -----TIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFT 3992
Query: 607 SPGRT---PLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGK------TPASIRK 657
+P T PL+ V++ + + +T + T A + +T P S TP+S
Sbjct: 3993 TPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESS 4052
Query: 658 PPSSV 662
PS++
Sbjct: 4053 RPSTI 4057
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 58.5 bits (140), Expect = 2e-08
Identities = 90/405 (22%), Positives = 150/405 (37%), Gaps = 58/405 (14%)
Query: 311 TPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVR 370
TP+P S N + +P VP + P P S + G SV+
Sbjct: 1138 TPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVK 1197
Query: 371 SKLPNSPAA-SSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPCIS 429
+ P A P + + +T +P + + + +S+ T P +P TAP +
Sbjct: 1198 TPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSV-----KTPEPVVP-TAPELQ 1251
Query: 430 ESP-----------------RKCISSPNTPKAKVIPA-----QNSADLP--------EST 459
S RK SS TP+ V A S D P +
Sbjct: 1252 PSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTR 1311
Query: 460 LLPNKCSGKTQ----PKYLKHNHISSRDNAV----SHLAAHSNSSSKCPKLPKANIPVRP 511
N S KT P + +S D V + S ++ K P++ +P+ P
Sbjct: 1312 SRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAP 1371
Query: 512 KPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSP 571
+ +S + T T G +++ S P+ A KL+ + + +QPV+ S
Sbjct: 1372 ELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQ 1431
Query: 572 V------KATQKSKDKNIVSATKKQPQNKSAFQKT-GPSSLKSPGRTPLSIVSLPQSSTK 624
+++ K+ + + +A + QP + T P+S + GRT S V P+ T
Sbjct: 1432 ATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPE--TV 1489
Query: 625 TQTAPKSAQTVAKSQHSTKGP----PRSGKTPASIRKPPSSVKDA 665
TAP+ + + Q T P R K +S++ P + V A
Sbjct: 1490 VPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAA 1534
Score = 51.6 bits (122), Expect = 2e-06
Identities = 90/416 (21%), Positives = 146/416 (35%), Gaps = 63/416 (15%)
Query: 304 VPDSPARTP-----QPPEMNPLSAVNMFQKQNSKPSVPVSI-PKSKEKQGRP----PGAL 353
VP +P P QP P S V +K S P ++ P + E Q P
Sbjct: 1162 VPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTS 1221
Query: 354 VPASSLKGGNLGSMSVRSKLPNSPAASS-HPKLKSSKGITKKPQAPSNNAS---SSLASL 409
P S G SV++ P P A P + + +T +P + SS+ +
Sbjct: 1222 EPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTP 1281
Query: 410 NPV---------GKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTL 460
PV +T P P+ + S R +SS TP+ V+P + ST
Sbjct: 1282 EPVVPTAPELRPSTSTDRPVTPKPTSRTTRS-RTNMSSVKTPET-VVPTAPELQISTSTD 1339
Query: 461 LP--NKCSGKTQPKYLKHNHISSRDNAV--------------------SHLAAHSNSSSK 498
P K + +T + + + ++ V + A +
Sbjct: 1340 QPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRS 1399
Query: 499 CPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSAL 558
K P+ +P PK +S T T G ++ S P+ A +L+ +
Sbjct: 1400 SGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPST 1459
Query: 559 NLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTG---------PSSLKSPG 609
+ +QPV+ S +AT+ D++ V + Q + P+S + G
Sbjct: 1460 STDQPVTPEPTS--QATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRG 1517
Query: 610 RTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGP---PRSGKTPASIRKPPSSV 662
R S V P+ T AP+ + + Q T P G+T S K P S+
Sbjct: 1518 RKNRSSVKTPE--TVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESI 1571
Score = 48.5 bits (114), Expect = 2e-05
Identities = 78/347 (22%), Positives = 127/347 (36%), Gaps = 67/347 (19%)
Query: 349 PPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLAS 408
P A VP+ S GG +S R + KG+ P+ AS A+
Sbjct: 979 PTSAPVPSGSQSGGRGSPVSPR---------------RHQKGLLNCKMPPAEKASRIRAA 1023
Query: 409 LNPVGKNTSSP--ALPRTAPCISESPRKCISSPNT-----------------PKAKVIPA 449
+ SP LP T P P+K ++S + P +
Sbjct: 1024 EKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQ 1083
Query: 450 QNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPV 509
S + PE+ L S + +P + K + + + ++ A S + P A PV
Sbjct: 1084 DGSQEAPEAPL-----SSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQ-PV 1137
Query: 510 RPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSV 569
PKP+ Q++ T SS P+ A +L+ + + +QPV+
Sbjct: 1138 TPKPTSQATRSRTNRSSVK--------------TPEPVVPTAPELQPSTSTDQPVTSEPT 1183
Query: 570 SPVKATQKSK------DKNIVSATKKQPQNKSAFQKTG-PSSLKSPGRTPLSIVSLPQSS 622
S V +KS+ + + +A + QP + T P+S + GR S V P+
Sbjct: 1184 SQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPE-- 1241
Query: 623 TKTQTAPKSAQTVAKSQHSTKGP----PRSGKTPASIRKPPSSVKDA 665
TAP+ + + Q T P R K +S++ P V A
Sbjct: 1242 PVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTA 1288
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 57.8 bits (138), Expect = 3e-08
Identities = 84/414 (20%), Positives = 145/414 (35%), Gaps = 51/414 (12%)
Query: 303 SVPDSPARTPQPPEMNPLSAVNMFQK--QNSKPSVPVSIPKSKEKQGRPPGALVPASSLK 360
+ P+ PA T P E+ P + + P+ P + + K+ P PA +
Sbjct: 501 TTPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 361 GGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPA 420
+ + P +P ++ LK T K AP A ++ + +P
Sbjct: 560 K-EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618
Query: 421 LPR-TAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQ-PKYLKHNH 478
P+ TAP + P +P TPK P P + P + K PK L
Sbjct: 619 TPKGTAPTTPKEP-----APTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672
Query: 479 ISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQ-- 536
+ S A + P PK P PK ++ + ++ ++T T+
Sbjct: 673 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 732
Query: 537 ----SQPSDGAPQ--AKPVPAQKLKSALNLNQPVS-VSSVSPVKATQKSKD--------- 580
P + P+ A+P P S P + + + + T +KD
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792
Query: 581 ------------KNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSS-----T 623
K + T+K ++K T +S + TP I +L ++ T
Sbjct: 793 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852
Query: 624 KTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKK 677
T+ + + + K + + K R+ + A+ KP K KKPT+ KK
Sbjct: 853 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK----APKKPTSTKK 902
Score = 56.2 bits (134), Expect = 1e-07
Identities = 79/360 (21%), Positives = 123/360 (34%), Gaps = 45/360 (12%)
Query: 343 KEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNA 402
K+ +PP S L G+ + + S+ PK+ ++K I +P P N+
Sbjct: 76 KKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 135
Query: 403 SSSLASL-------------NPVGKNTSSPALPRTAPCISE-----------SPRKCISS 438
+S SL K TS+ +T +P + +
Sbjct: 136 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 195
Query: 439 PNTPKAKVIPAQNSADLP-ESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLA-AHSNSS 496
TPKA+ + P E T K T PK I S A + S+
Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 255
Query: 497 SKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKS 556
PK P P P+ T T T + P + AP PA
Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP- 314
Query: 557 ALNLNQPVSVSSVSPVKATQKS---KDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPL 613
+P + P T K K T K+P +A +K P++ K P T
Sbjct: 315 ----KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPKKPAPTTPKEPAPT-- 367
Query: 614 SIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPT 673
P +T + +P + + A + +TK P + K PA P++ K A + K+P+
Sbjct: 368 -TPKEPAPTTTKEPSPTTPKEPAPT--TTKSAPTTTKEPA-----PTTTKSAPTTPKEPS 419
Score = 53.1 bits (126), Expect = 8e-07
Identities = 86/406 (21%), Positives = 131/406 (32%), Gaps = 60/406 (14%)
Query: 307 SPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGS 366
+P T P A + + P P S +KE P P + K
Sbjct: 389 APTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447
Query: 367 MSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAP 426
P PA ++ K + P P A ++ L P +P P
Sbjct: 448 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---- 503
Query: 427 CISESPRKCISSPNTPK--AKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDN 484
E P +P TP+ A P + + PE T PK
Sbjct: 504 ---EKP-----APTTPEELAPTTPEEPTPTTPEE-------PAPTTPK------------ 536
Query: 485 AVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAP 544
AA + P PK P PK ++ K T ++ T T +P AP
Sbjct: 537 ----AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK-GTAPTTLKEP---AP 588
Query: 545 QAKPVPAQKLKSALNLNQPVSVSSVSPV----KATQKSKDKNIVSATKKQPQNKSAFQKT 600
PA K + +P S + P K T + K T K+P + + T
Sbjct: 589 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP-KGT 647
Query: 601 GPSSLKSPGRT------PLSIVSL----PQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGK 650
P++LK P T P + P S+T + AP + + A + P K
Sbjct: 648 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 707
Query: 651 -TPASIRKPPSSVKDAD--SGDKKPTAKKKEDDDHYFVMTGSKKPR 693
P + PP + + + K+PT K D+ ++ P+
Sbjct: 708 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 753
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 57.8 bits (138), Expect = 3e-08
Identities = 84/414 (20%), Positives = 145/414 (35%), Gaps = 51/414 (12%)
Query: 303 SVPDSPARTPQPPEMNPLSAVNMFQK--QNSKPSVPVSIPKSKEKQGRPPGALVPASSLK 360
+ P+ PA T P E+ P + + P+ P + + K+ P PA +
Sbjct: 542 TTPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 361 GGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPA 420
+ + P +P ++ LK T K AP A ++ + +P
Sbjct: 601 K-EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659
Query: 421 LPR-TAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQ-PKYLKHNH 478
P+ TAP + P +P TPK P P + P + K PK L
Sbjct: 660 TPKGTAPTTPKEP-----APTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713
Query: 479 ISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQ-- 536
+ S A + P PK P PK ++ + ++ ++T T+
Sbjct: 714 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 773
Query: 537 ----SQPSDGAPQ--AKPVPAQKLKSALNLNQPVS-VSSVSPVKATQKSKD--------- 580
P + P+ A+P P S P + + + + T +KD
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833
Query: 581 ------------KNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSS-----T 623
K + T+K ++K T +S + TP I +L ++ T
Sbjct: 834 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893
Query: 624 KTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKK 677
T+ + + + K + + K R+ + A+ KP K KKPT+ KK
Sbjct: 894 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK----APKKPTSTKK 943
Score = 56.2 bits (134), Expect = 1e-07
Identities = 79/360 (21%), Positives = 123/360 (34%), Gaps = 45/360 (12%)
Query: 343 KEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNA 402
K+ +PP S L G+ + + S+ PK+ ++K I +P P N+
Sbjct: 117 KKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 176
Query: 403 SSSLASL-------------NPVGKNTSSPALPRTAPCISE-----------SPRKCISS 438
+S SL K TS+ +T +P + +
Sbjct: 177 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 236
Query: 439 PNTPKAKVIPAQNSADLP-ESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLA-AHSNSS 496
TPKA+ + P E T K T PK I S A + S+
Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 296
Query: 497 SKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKS 556
PK P P P+ T T T + P + AP PA
Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP- 355
Query: 557 ALNLNQPVSVSSVSPVKATQKS---KDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPL 613
+P + P T K K T K+P +A +K P++ K P T
Sbjct: 356 ----KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPKKPAPTTPKEPAPT-- 408
Query: 614 SIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPT 673
P +T + +P + + A + +TK P + K PA P++ K A + K+P+
Sbjct: 409 -TPKEPAPTTTKEPSPTTPKEPAPT--TTKSAPTTTKEPA-----PTTTKSAPTTPKEPS 460
Score = 53.1 bits (126), Expect = 8e-07
Identities = 86/406 (21%), Positives = 131/406 (32%), Gaps = 60/406 (14%)
Query: 307 SPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGS 366
+P T P A + + P P S +KE P P + K
Sbjct: 430 APTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488
Query: 367 MSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAP 426
P PA ++ K + P P A ++ L P +P P
Sbjct: 489 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---- 544
Query: 427 CISESPRKCISSPNTPK--AKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDN 484
E P +P TP+ A P + + PE T PK
Sbjct: 545 ---EKP-----APTTPEELAPTTPEEPTPTTPEE-------PAPTTPK------------ 577
Query: 485 AVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAP 544
AA + P PK P PK ++ K T ++ T T +P AP
Sbjct: 578 ----AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK-GTAPTTLKEP---AP 629
Query: 545 QAKPVPAQKLKSALNLNQPVSVSSVSPV----KATQKSKDKNIVSATKKQPQNKSAFQKT 600
PA K + +P S + P K T + K T K+P + + T
Sbjct: 630 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP-KGT 688
Query: 601 GPSSLKSPGRT------PLSIVSL----PQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGK 650
P++LK P T P + P S+T + AP + + A + P K
Sbjct: 689 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 748
Query: 651 -TPASIRKPPSSVKDAD--SGDKKPTAKKKEDDDHYFVMTGSKKPR 693
P + PP + + + K+PT K D+ ++ P+
Sbjct: 749 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 794
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 57.8 bits (138), Expect = 3e-08
Identities = 84/414 (20%), Positives = 145/414 (35%), Gaps = 51/414 (12%)
Query: 303 SVPDSPARTPQPPEMNPLSAVNMFQK--QNSKPSVPVSIPKSKEKQGRPPGALVPASSLK 360
+ P+ PA T P E+ P + + P+ P + + K+ P PA +
Sbjct: 594 TTPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 652
Query: 361 GGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPA 420
+ + P +P ++ LK T K AP A ++ + +P
Sbjct: 653 K-EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 711
Query: 421 LPR-TAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQ-PKYLKHNH 478
P+ TAP + P +P TPK P P + P + K PK L
Sbjct: 712 TPKGTAPTTPKEP-----APTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765
Query: 479 ISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQ-- 536
+ S A + P PK P PK ++ + ++ ++T T+
Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 825
Query: 537 ----SQPSDGAPQ--AKPVPAQKLKSALNLNQPVS-VSSVSPVKATQKSKD--------- 580
P + P+ A+P P S P + + + + T +KD
Sbjct: 826 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885
Query: 581 ------------KNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSS-----T 623
K + T+K ++K T +S + TP I +L ++ T
Sbjct: 886 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 945
Query: 624 KTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKK 677
T+ + + + K + + K R+ + A+ KP K KKPT+ KK
Sbjct: 946 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK----APKKPTSTKK 995
Score = 57.4 bits (137), Expect = 4e-08
Identities = 85/400 (21%), Positives = 139/400 (34%), Gaps = 39/400 (9%)
Query: 300 SNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSL 359
S+ S S + T + + + SA N ++ K K+ +PP S L
Sbjct: 126 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL 185
Query: 360 KGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLN--------- 410
G+ + + S+ PK+ ++K I +P P N+ +S SL
Sbjct: 186 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 245
Query: 411 ----PVGKNTSSPALPRTAPCISE-----------SPRKCISSPNTPKAKVIPAQNSADL 455
K TS+ +T +P + + TPKA+ +
Sbjct: 246 KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 305
Query: 456 P-ESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKC-PKLPKANIPVRPKP 513
P E T K T PK I S A + S+ PK P P P
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 365
Query: 514 SFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVK 573
+ T T T + P + AP PA P + +P +
Sbjct: 366 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 425
Query: 574 ATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQ 633
+K+ T K+P +A +K P++ K P T P +T + +P + +
Sbjct: 426 PAPTTKEP--APTTPKEPA-PTAPKKPAPTTPKEPAPT---TPKEPAPTTTKEPSPTTPK 479
Query: 634 TVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPT 673
A + +TK P + K PA P++ K A + K+P+
Sbjct: 480 EPAPT--TTKSAPTTTKEPA-----PTTTKSAPTTPKEPS 512
Score = 53.1 bits (126), Expect = 8e-07
Identities = 86/406 (21%), Positives = 131/406 (32%), Gaps = 60/406 (14%)
Query: 307 SPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGS 366
+P T P A + + P P S +KE P P + K
Sbjct: 482 APTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTP 540
Query: 367 MSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAP 426
P PA ++ K + P P A ++ L P +P P
Sbjct: 541 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---- 596
Query: 427 CISESPRKCISSPNTPK--AKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDN 484
E P +P TP+ A P + + PE T PK
Sbjct: 597 ---EKP-----APTTPEELAPTTPEEPTPTTPEE-------PAPTTPK------------ 629
Query: 485 AVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAP 544
AA + P PK P PK ++ K T ++ T T +P AP
Sbjct: 630 ----AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK-GTAPTTLKEP---AP 681
Query: 545 QAKPVPAQKLKSALNLNQPVSVSSVSPV----KATQKSKDKNIVSATKKQPQNKSAFQKT 600
PA K + +P S + P K T + K T K+P + + T
Sbjct: 682 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP-KGT 740
Query: 601 GPSSLKSPGRT------PLSIVSL----PQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGK 650
P++LK P T P + P S+T + AP + + A + P K
Sbjct: 741 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 800
Query: 651 -TPASIRKPPSSVKDAD--SGDKKPTAKKKEDDDHYFVMTGSKKPR 693
P + PP + + + K+PT K D+ ++ P+
Sbjct: 801 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 846
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 57.8 bits (138), Expect = 3e-08
Identities = 84/414 (20%), Positives = 145/414 (35%), Gaps = 51/414 (12%)
Query: 303 SVPDSPARTPQPPEMNPLSAVNMFQK--QNSKPSVPVSIPKSKEKQGRPPGALVPASSLK 360
+ P+ PA T P E+ P + + P+ P + + K+ P PA +
Sbjct: 635 TTPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 693
Query: 361 GGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPA 420
+ + P +P ++ LK T K AP A ++ + +P
Sbjct: 694 K-EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 752
Query: 421 LPR-TAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQ-PKYLKHNH 478
P+ TAP + P +P TPK P P + P + K PK L
Sbjct: 753 TPKGTAPTTPKEP-----APTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806
Query: 479 ISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQ-- 536
+ S A + P PK P PK ++ + ++ ++T T+
Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 866
Query: 537 ----SQPSDGAPQ--AKPVPAQKLKSALNLNQPVS-VSSVSPVKATQKSKD--------- 580
P + P+ A+P P S P + + + + T +KD
Sbjct: 867 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926
Query: 581 ------------KNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSS-----T 623
K + T+K ++K T +S + TP I +L ++ T
Sbjct: 927 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 986
Query: 624 KTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKK 677
T+ + + + K + + K R+ + A+ KP K KKPT+ KK
Sbjct: 987 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK----APKKPTSTKK 1036
Score = 57.4 bits (137), Expect = 4e-08
Identities = 85/400 (21%), Positives = 139/400 (34%), Gaps = 39/400 (9%)
Query: 300 SNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSL 359
S+ S S + T + + + SA N ++ K K+ +PP S L
Sbjct: 167 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL 226
Query: 360 KGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLN--------- 410
G+ + + S+ PK+ ++K I +P P N+ +S SL
Sbjct: 227 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 286
Query: 411 ----PVGKNTSSPALPRTAPCISE-----------SPRKCISSPNTPKAKVIPAQNSADL 455
K TS+ +T +P + + TPKA+ +
Sbjct: 287 KETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 346
Query: 456 P-ESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKC-PKLPKANIPVRPKP 513
P E T K T PK I S A + S+ PK P P P
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 406
Query: 514 SFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVK 573
+ T T T + P + AP PA P + +P +
Sbjct: 407 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 466
Query: 574 ATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQ 633
+K+ T K+P +A +K P++ K P T P +T + +P + +
Sbjct: 467 PAPTTKEP--APTTPKEPA-PTAPKKPAPTTPKEPAPT---TPKEPAPTTTKEPSPTTPK 520
Query: 634 TVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPT 673
A + +TK P + K PA P++ K A + K+P+
Sbjct: 521 EPAPT--TTKSAPTTTKEPA-----PTTTKSAPTTPKEPS 553
Score = 53.1 bits (126), Expect = 8e-07
Identities = 86/406 (21%), Positives = 131/406 (32%), Gaps = 60/406 (14%)
Query: 307 SPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGS 366
+P T P A + + P P S +KE P P + K
Sbjct: 523 APTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTP 581
Query: 367 MSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAP 426
P PA ++ K + P P A ++ L P +P P
Sbjct: 582 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---- 637
Query: 427 CISESPRKCISSPNTPK--AKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDN 484
E P +P TP+ A P + + PE T PK
Sbjct: 638 ---EKP-----APTTPEELAPTTPEEPTPTTPEE-------PAPTTPK------------ 670
Query: 485 AVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAP 544
AA + P PK P PK ++ K T ++ T T +P AP
Sbjct: 671 ----AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK-GTAPTTLKEP---AP 722
Query: 545 QAKPVPAQKLKSALNLNQPVSVSSVSPV----KATQKSKDKNIVSATKKQPQNKSAFQKT 600
PA K + +P S + P K T + K T K+P + + T
Sbjct: 723 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP-KGT 781
Query: 601 GPSSLKSPGRT------PLSIVSL----PQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGK 650
P++LK P T P + P S+T + AP + + A + P K
Sbjct: 782 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 841
Query: 651 -TPASIRKPPSSVKDAD--SGDKKPTAKKKEDDDHYFVMTGSKKPR 693
P + PP + + + K+PT K D+ ++ P+
Sbjct: 842 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 887
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 57.8 bits (138), Expect = 3e-08
Identities = 83/382 (21%), Positives = 148/382 (38%), Gaps = 38/382 (9%)
Query: 308 PARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSM 367
P RTP + S+ S+ P + G P A + + + G+
Sbjct: 4 PTRTPSRASPTRTPSTASLTGTPSRASL-TGTPSTASLMGTPSRASLTGTPPRASLKGTT 62
Query: 368 SVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPC 427
S+ S L SP+ +S +++SS +T+ P + +SL + P T + LPR +
Sbjct: 63 SMAS-LMVSPSRASLTRMQSSSLLTRTP------SMASLKRMPPRASRTRT--LPRASLM 113
Query: 428 ISESPRKCISSPNTPKAKVIPAQNSADLPESTL----LPNKCS-GKTQPKYLKHNHISSR 482
S SP+ P++ S + ST +P++ S +T P+
Sbjct: 114 RRPSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRA--------- 164
Query: 483 DNAVSHLAAHSNSSSKCPKLPKANIPVRPKPS-FQSSAKMTKTSSKTIATGLGTQSQPSD 541
+++ + ++ + P+ +P R P+ S+A +TK S T +++ P+
Sbjct: 165 --SLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTG 222
Query: 542 GAPQAKPV---PAQKLK----SALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNK 594
P+A P P L +AL + P S + T +K + S T+ P
Sbjct: 223 TPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRT-PSRP 281
Query: 595 SAFQKTGPSSLKSPGRTPLS---IVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKT 651
S TG S S TP + + LP++S + S + + ++ PPR+ T
Sbjct: 282 STASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASIT 341
Query: 652 PASIRKPPSSVKDADSGDKKPT 673
R P+ S P+
Sbjct: 342 RTPSRASPTGKPSTASPTGTPS 363
Score = 51.2 bits (121), Expect = 3e-06
Identities = 86/425 (20%), Positives = 147/425 (34%), Gaps = 61/425 (14%)
Query: 307 SPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGA-----------LVP 355
SP RTP + + S S+ + P G PP A +V
Sbjct: 12 SPTRTPSTASLTGTPSRASLTGTPSTASL-MGTPSRASLTGTPPRASLKGTTSMASLMVS 70
Query: 356 ASSLKGGNLGSMSVRSKLPNS------PAASSHPKLKSSKGITKKPQAPSNNASSSLASL 409
S + S S+ ++ P+ P +S + + ++P S S S ASL
Sbjct: 71 PSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRASL 130
Query: 410 NPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPES------TLLPN 463
S P TA ++ P + + P+A + ++A L + T +P+
Sbjct: 131 TTTPSRASLSMTPSTAAALT-MPSRASLTRTPPRASLTMTPSTASLTRTPPRASPTGMPS 189
Query: 464 KCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTK 523
+ S P + S + L+ S + + P + P S+A + +
Sbjct: 190 RTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIR 249
Query: 524 TSSKTIATGL----------------GTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVS 567
T + TG+ T S+PS +P P A + + +
Sbjct: 250 TPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLP 309
Query: 568 SVSP---VKATQKSKDKNIVSATKKQP-----QNKSAFQKTGPSSLKSPGRTP------- 612
SP + T +K + S ++ P + S TG S SP TP
Sbjct: 310 RASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTG 369
Query: 613 ----LSIVSLPQSSTKTQTAPKSAQTVAKSQHS-TKGPPRSGKTPASIRKPPSSVKDADS 667
S+ L +++ T T P+++ T S S T+ PPR+ T R + + S
Sbjct: 370 SPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTAS 429
Query: 668 GDKKP 672
+ P
Sbjct: 430 PTRTP 434
Score = 48.1 bits (113), Expect = 3e-05
Identities = 77/349 (22%), Positives = 134/349 (38%), Gaps = 40/349 (11%)
Query: 336 PVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKP 395
P P + G P A P S +L +S + +P +S S+ +T+KP
Sbjct: 349 PTGKPSTASPTGTPSRAS-PTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKP 407
Query: 396 QAPSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADL 455
S S S+ + +T+SP RT P S + +SP ++ P
Sbjct: 408 PRASPTGMLSRTSITKM-DSTASPT--RTPPRASPTGTPPRASPTGTPSRASPTGT---- 460
Query: 456 PESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSS-SKCPKLPKANIPVRPKPS 514
+ST P P + + S + S +S ++ P +A++
Sbjct: 461 -QSTASPTGSPSTASP--------TGSPSTASPTGSPSRASLTRTPS--RASL-----TK 504
Query: 515 FQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSAL-------NLNQPVSVS 567
+S+A +T+T S+ T + + P+ G+P ++AL +L + S +
Sbjct: 505 MESTASITRTPSRASPTWTPSTASPT-GSPSTALAMGSPSRAALTRTPSRASLTRTPSRA 563
Query: 568 SVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTK--T 625
S++ ++ + V T+ P + TG S SP P S + ST T
Sbjct: 564 SLTTPSRASLTRTPSTVLLTRMPP----SASPTGMPSRTSPTGMPSSALLTKMDSTASIT 619
Query: 626 QTAPKSAQTVAKSQHSTKG-PPRSGKTPASIRKPPSSVKDADSGDKKPT 673
+T P+++ T + S G PPR+ T R P+ S P+
Sbjct: 620 RTPPRASPTETPPRASPTGTPPRASPTGTPPRASPTGTPPRASPTGTPS 668
Score = 45.1 bits (105), Expect = 2e-04
Identities = 72/329 (21%), Positives = 120/329 (36%), Gaps = 50/329 (15%)
Query: 355 PASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGK 414
P L +L M + + +P +S + S T KP S + S AS
Sbjct: 313 PTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPS 372
Query: 415 NTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYL 474
S L TA S TP P + P + L K + L
Sbjct: 373 TASLTGLSSTA-----------SPTGTP-----PRASPTGTPSTASLTRKPPRASPTGML 416
Query: 475 KHNHISSRDNAVS--HLAAHSNSSSKCPKLPKANIPVRPKPS-FQSSAKMTKTSSKTIAT 531
I+ D+ S ++ + P+ P R P+ QS+A T + S T
Sbjct: 417 SRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPT 476
Query: 532 GLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQP 591
G PS +P P S +L + S +S++ +++T ++ + P
Sbjct: 477 G-----SPSTASPTGSP-------SRASLTRTPSRASLTKMEST---------ASITRTP 515
Query: 592 QNKSAFQKTGPSSLKSPGRTPLSIVSL--PQSSTKTQTAPKSAQTVAKSQHSTKGPPRSG 649
S T S SP +P + +++ P + T+T +++ T S+ S P R+
Sbjct: 516 SRAS---PTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRAS 572
Query: 650 --KTPASI---RKPPSSVKDADSGDKKPT 673
+TP+++ R PPS+ PT
Sbjct: 573 LTRTPSTVLLTRMPPSASPTGMPSRTSPT 601
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 56.6 bits (135), Expect = 8e-08
Identities = 84/401 (20%), Positives = 145/401 (36%), Gaps = 35/401 (8%)
Query: 302 ESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKG 361
E PA PE S V K+ +K P+ KE+ P P
Sbjct: 499 EETKSPPAEEAASPEKEAKSPV----KEEAKSPAEAKSPE-KEEAKSPAEVKSPE----- 548
Query: 362 GNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPAL 421
++K P A S P+ KS + ++ ++P+ S A +P + SPA
Sbjct: 549 --------KAKSPAKEEAKSPPEAKSPE--KEEAKSPAEVKSPEKAK-SPAKEEAKSPAE 597
Query: 422 PRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISS 481
+ +P ++SP K +P P + A P P K T+ + S
Sbjct: 598 AK-SPEKAKSPVK--EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 482 --RDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKM-TKTSSKTIATGLGTQSQ 538
++ A S A S ++ KA PV+ + AK K +K+ +
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 539 PSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKA--TQKSKDKNIVSATKKQPQNKSA 596
+ +AK ++ K+ PV + SP KA +K+K ++ S K P + A
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 597 FQKTG--PSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTP-- 652
P KSP + + +S K K+ + + K P + + P
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDA--KAPEKEIPKKEEVKSPVKEEEKPQE 832
Query: 653 ASIRKPPSSVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPR 693
+++PP ++ + T +KK+ + KP+
Sbjct: 833 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPK 873
Score = 40.4 bits (93), Expect = 0.006
Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 10/170 (5%)
Query: 534 GTQSQPSDGAPQAKPVPAQKLKSA-LNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQ 592
G + + G + K PA++ S PV + SP +A K++ A K P+
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548
Query: 593 NKSAFQKT---GPSSLKSP----GRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGP 645
+ K P KSP ++P + S ++ + + KS AKS K P
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE-AKSPEKAKSP 607
Query: 646 PRS-GKTPASIRKPPSSVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK 694
+ K+PA + P + + K P K + +K P K
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 56.2 bits (134), Expect = 1e-07
Identities = 95/403 (23%), Positives = 152/403 (37%), Gaps = 56/403 (13%)
Query: 302 ESVPDSPARTPQPPEMN-PLSAVNMFQ-KQNSKPSVPVS--------IPKSKEKQGRPPG 351
+ +P S A T P + + P S+ Q K+ P P +PKS EK +P
Sbjct: 20 DDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKE 79
Query: 352 ALVPASSLKG--GNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASL 409
+ +P SS K LG++ S P+ P PK +KK P ++ +
Sbjct: 80 SNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKE 139
Query: 410 NPVGKNTSSPALPR----TAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLP--- 462
+ K+++ P P+ + S K P +P+ + P + D+P+S+ P
Sbjct: 140 GDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKE--GDIPKSSAKPIQP 197
Query: 463 ---NKCSGKTQPKYLKHNHIS-SRDNAVSHLAAHSNSSSKCPKLPK-ANIPVRPKPSFQS 517
N +P K IS S + A+ S + PK +IP P+ + Q
Sbjct: 198 KLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQ- 256
Query: 518 SAKMTKTSSKTIATGLGTQSQPSDG-APQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQ 576
I L QP +G P++ Q K + SP +A Q
Sbjct: 257 ------PKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDI---------PKSPEEAIQ 301
Query: 577 KSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVA 636
K+ +I + K+ Q K + P SL+ P + +P+S +T PK +
Sbjct: 302 -PKEGDIPKSPKQAIQPK---EGDIPKSLEE--AIPPKEIDIPKSPEET-IQPKEDDSPK 354
Query: 637 KSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKED 679
+ +T P + G I KP + GDK KED
Sbjct: 355 SLEEAT--PSKEG----DILKPEEETMEFPEGDKVKVILSKED 391
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 56.2 bits (134), Expect = 1e-07
Identities = 95/403 (23%), Positives = 152/403 (37%), Gaps = 56/403 (13%)
Query: 302 ESVPDSPARTPQPPEMN-PLSAVNMFQ-KQNSKPSVPVS--------IPKSKEKQGRPPG 351
+ +P S A T P + + P S+ Q K+ P P +PKS EK +P
Sbjct: 87 DDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKE 146
Query: 352 ALVPASSLKG--GNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASL 409
+ +P SS K LG++ S P+ P PK +KK P ++ +
Sbjct: 147 SNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKE 206
Query: 410 NPVGKNTSSPALPR----TAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLP--- 462
+ K+++ P P+ + S K P +P+ + P + D+P+S+ P
Sbjct: 207 GDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKE--GDIPKSSAKPIQP 264
Query: 463 ---NKCSGKTQPKYLKHNHIS-SRDNAVSHLAAHSNSSSKCPKLPK-ANIPVRPKPSFQS 517
N +P K IS S + A+ S + PK +IP P+ + Q
Sbjct: 265 KLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQ- 323
Query: 518 SAKMTKTSSKTIATGLGTQSQPSDG-APQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQ 576
I L QP +G P++ Q K + SP +A Q
Sbjct: 324 ------PKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDI---------PKSPEEAIQ 368
Query: 577 KSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVA 636
K+ +I + K+ Q K + P SL+ P + +P+S +T PK +
Sbjct: 369 -PKEGDIPKSPKQAIQPK---EGDIPKSLEE--AIPPKEIDIPKSPEET-IQPKEDDSPK 421
Query: 637 KSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKED 679
+ +T P + G I KP + GDK KED
Sbjct: 422 SLEEAT--PSKEG----DILKPEEETMEFPEGDKVKVILSKED 458
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 56.2 bits (134), Expect = 1e-07
Identities = 95/403 (23%), Positives = 152/403 (37%), Gaps = 56/403 (13%)
Query: 302 ESVPDSPARTPQPPEMN-PLSAVNMFQ-KQNSKPSVPVS--------IPKSKEKQGRPPG 351
+ +P S A T P + + P S+ Q K+ P P +PKS EK +P
Sbjct: 20 DDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKE 79
Query: 352 ALVPASSLKG--GNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASL 409
+ +P SS K LG++ S P+ P PK +KK P ++ +
Sbjct: 80 SNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKE 139
Query: 410 NPVGKNTSSPALPR----TAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLP--- 462
+ K+++ P P+ + S K P +P+ + P + D+P+S+ P
Sbjct: 140 GDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKE--GDIPKSSAKPIQP 197
Query: 463 ---NKCSGKTQPKYLKHNHIS-SRDNAVSHLAAHSNSSSKCPKLPK-ANIPVRPKPSFQS 517
N +P K IS S + A+ S + PK +IP P+ + Q
Sbjct: 198 KLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQ- 256
Query: 518 SAKMTKTSSKTIATGLGTQSQPSDG-APQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQ 576
I L QP +G P++ Q K + SP +A Q
Sbjct: 257 ------PKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDI---------PKSPEEAIQ 301
Query: 577 KSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVA 636
K+ +I + K+ Q K + P SL+ P + +P+S +T PK +
Sbjct: 302 -PKEGDIPKSPKQAIQPK---EGDIPKSLEE--AIPPKEIDIPKSPEET-IQPKEDDSPK 354
Query: 637 KSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKED 679
+ +T P + G I KP + GDK KED
Sbjct: 355 SLEEAT--PSKEG----DILKPEEETMEFPEGDKVKVILSKED 391
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 30/144 (20%)
Query: 215 EAVKHIAEDPPCSCSHRFSIEYLSEGRYRL------GD--KILFIRMLHGKHVMVRVGGG 266
E + +A+ C C+ RF +E + + +YR GD ++ +R+L VMVRVGGG
Sbjct: 5224 EVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGGG 5279
Query: 267 WDTLQGFLLKYDPCRILQFATLE------------QKILAFQKGVSNESVPDSPARTPQP 314
W L FL+K DPCR +E Q + AF+ S P S +P
Sbjct: 5280 WMALDEFLVKNDPCRAKGRTNMELREKFILADGASQGMAAFRPR-GRRSRPSSRGASP-- 5336
Query: 315 PEMNPLSAVNMFQKQNSKPSVPVS 338
N ++V+ Q + P VP +
Sbjct: 5337 ---NRSTSVSSQAAQAASPQVPAT 5357
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 30/144 (20%)
Query: 215 EAVKHIAEDPPCSCSHRFSIEYLSEGRYRL------GD--KILFIRMLHGKHVMVRVGGG 266
E + +A+ C C+ RF +E + + +YR GD ++ +R+L VMVRVGGG
Sbjct: 5235 EVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGGG 5290
Query: 267 WDTLQGFLLKYDPCRILQFATLE------------QKILAFQKGVSNESVPDSPARTPQP 314
W L FL+K DPCR +E Q + AF+ S P S +P
Sbjct: 5291 WMALDEFLVKNDPCRAKGRTNMELREKFILADGASQGMAAFRPR-GRRSRPSSRGASP-- 5347
Query: 315 PEMNPLSAVNMFQKQNSKPSVPVS 338
N ++V+ Q + P VP +
Sbjct: 5348 ---NRSTSVSSQAAQAASPQVPAT 5368
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 30/144 (20%)
Query: 215 EAVKHIAEDPPCSCSHRFSIEYLSEGRYRL------GD--KILFIRMLHGKHVMVRVGGG 266
E + +A+ C C+ RF +E + + +YR GD ++ +R+L VMVRVGGG
Sbjct: 5373 EVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGGG 5428
Query: 267 WDTLQGFLLKYDPCRILQFATLE------------QKILAFQKGVSNESVPDSPARTPQP 314
W L FL+K DPCR +E Q + AF+ S P S +P
Sbjct: 5429 WMALDEFLVKNDPCRAKGRTNMELREKFILADGASQGMAAFRPR-GRRSRPSSRGASP-- 5485
Query: 315 PEMNPLSAVNMFQKQNSKPSVPVS 338
N ++V+ Q + P VP +
Sbjct: 5486 ---NRSTSVSSQAAQAASPQVPAT 5506
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 30/144 (20%)
Query: 215 EAVKHIAEDPPCSCSHRFSIEYLSEGRYRL------GD--KILFIRMLHGKHVMVRVGGG 266
E + +A+ C C+ RF +E + + +YR GD ++ +R+L VMVRVGGG
Sbjct: 5195 EVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGGG 5250
Query: 267 WDTLQGFLLKYDPCRILQFATLE------------QKILAFQKGVSNESVPDSPARTPQP 314
W L FL+K DPCR +E Q + AF+ S P S +P
Sbjct: 5251 WMALDEFLVKNDPCRAKGRTNMELREKFILADGASQGMAAFRPR-GRRSRPSSRGASP-- 5307
Query: 315 PEMNPLSAVNMFQKQNSKPSVPVS 338
N ++V+ Q + P VP +
Sbjct: 5308 ---NRSTSVSSQAAQAASPQVPAT 5328
>gi|34577049 dystonin isoform 1eA precursor [Homo sapiens]
Length = 5171
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 30/144 (20%)
Query: 215 EAVKHIAEDPPCSCSHRFSIEYLSEGRYRL------GD--KILFIRMLHGKHVMVRVGGG 266
E + +A+ C C+ RF +E + + +YR GD ++ +R+L VMVRVGGG
Sbjct: 4869 EVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGGG 4924
Query: 267 WDTLQGFLLKYDPCRILQFATLE------------QKILAFQKGVSNESVPDSPARTPQP 314
W L FL+K DPCR +E Q + AF+ S P S +P
Sbjct: 4925 WMALDEFLVKNDPCRAKGRTNMELREKFILADGASQGMAAFRPR-GRRSRPSSRGASP-- 4981
Query: 315 PEMNPLSAVNMFQKQNSKPSVPVS 338
N ++V+ Q + P VP +
Sbjct: 4982 ---NRSTSVSSQAAQAASPQVPAT 5002
>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
sapiens]
Length = 1135
Score = 54.7 bits (130), Expect = 3e-07
Identities = 81/381 (21%), Positives = 139/381 (36%), Gaps = 39/381 (10%)
Query: 301 NESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSV-PVSIPKSKEKQGRPPGALVPASSL 359
N+ +P SP + + PL+ + SK P S+PK +P + +
Sbjct: 690 NKELPPSPEK-----KTKPLATTQPAKTSTSKAKTQPTSLPK------QPAPTTIGGLNK 738
Query: 360 KGGNLGSMSVRSKLPNSPA-ASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSS 418
K +L S V + P PA AS+ P + SK + KP A + + +S
Sbjct: 739 KPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK-----------APEKRAS 787
Query: 419 PALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSG-KTQPKYLKHN 477
P+ P +AP + + T A + + + STLLP K + KT+ K +
Sbjct: 788 PSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 847
Query: 478 HISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGL---- 533
++++ S S+S K + S K T S+ T
Sbjct: 848 KMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKK 907
Query: 534 GTQSQPSDGAPQ----AKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKK 589
T ++PS P+ A A LK+ + P K + K +AT +
Sbjct: 908 PTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTR 967
Query: 590 QPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSG 649
+P++ + + GP + S + P V + + + Q+ S+ + K P G
Sbjct: 968 KPESNAVTKTAGP--IASAQKQPAGKVQI----VSKKVSYSHIQSKCGSKDNIKHVPGGG 1021
Query: 650 KTPASIRKPPSSVKDADSGDK 670
+K S + G K
Sbjct: 1022 NVQIQNKKVDISKVSSKCGSK 1042
Score = 39.7 bits (91), Expect = 0.010
Identities = 41/194 (21%), Positives = 69/194 (35%), Gaps = 28/194 (14%)
Query: 288 LEQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVN-------MFQKQNSKPSVPVSIP 340
L +K ++ G+ + P PA P + P V ++ + PS P S P
Sbjct: 736 LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAP 795
Query: 341 KSKE--KQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAA------SSHPKLKSSKGIT 392
S+ K + A+++ S S + LP P A + K ++K +
Sbjct: 796 ASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVP 855
Query: 393 KKPQAPSNNASSSLASLNPVG-------------KNTSSPALPRTAPCISESPRKCISSP 439
P + ++SS+ + K T P+ P T P I + P S
Sbjct: 856 ADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSS 915
Query: 440 NTPKAKVIPAQNSA 453
TP+ + SA
Sbjct: 916 TTPRLSRLATNTSA 929
Score = 35.0 bits (79), Expect = 0.23
Identities = 70/287 (24%), Positives = 109/287 (37%), Gaps = 63/287 (21%)
Query: 404 SSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPN 463
S L SL VG++ AP SP + T K +PA+ + L +
Sbjct: 605 SHLESLQDVGQSA--------APTFMISPE---TVTGTGKKCSLPAEEDSVLEKL----- 648
Query: 464 KCSGKTQPKYLKHNHISSRDNAVSH----LAAHSNSSSKCPKLPKANIPVRP----KPSF 515
G+ +P + + +SS + ++ S + + P +P P KP
Sbjct: 649 ---GERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLA 705
Query: 516 QSSAKMTKTS-SKTIATGLGTQSQPSD-GAPQAKPVP-AQKLKSALNLNQPVSVSSVSPV 572
+ T TS +KT T L Q P+ G KP+ A L A +P S+ +
Sbjct: 706 TTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSI 765
Query: 573 KATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSA 632
++ K K I A K P+ +++ K P S+ +++ KS
Sbjct: 766 LPSKDVKPKPIADA--KAPEKRASPSK-------------------PASAPASRSGSKST 804
Query: 633 QTVAKSQHSTKGPPRSGKTPASIRKP-PSSVKDADSGDKKPTAKKKE 678
QTVAK+ T A++ PSS + KKPTA K E
Sbjct: 805 QTVAKTT-----------TAAAVASTGPSSRSPSTLLPKKPTAIKTE 840
>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
sapiens]
Length = 887
Score = 54.7 bits (130), Expect = 3e-07
Identities = 81/381 (21%), Positives = 139/381 (36%), Gaps = 39/381 (10%)
Query: 301 NESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSV-PVSIPKSKEKQGRPPGALVPASSL 359
N+ +P SP + + PL+ + SK P S+PK +P + +
Sbjct: 425 NKELPPSPEK-----KTKPLATTQPAKTSTSKAKTQPTSLPK------QPAPTTIGGLNK 473
Query: 360 KGGNLGSMSVRSKLPNSPA-ASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSS 418
K +L S V + P PA AS+ P + SK + KP A + + +S
Sbjct: 474 KPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK-----------APEKRAS 522
Query: 419 PALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSG-KTQPKYLKHN 477
P+ P +AP + + T A + + + STLLP K + KT+ K +
Sbjct: 523 PSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVK 582
Query: 478 HISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGL---- 533
++++ S S+S K + S K T S+ T
Sbjct: 583 KMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKK 642
Query: 534 GTQSQPSDGAPQ----AKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKK 589
T ++PS P+ A A LK+ + P K + K +AT +
Sbjct: 643 PTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTR 702
Query: 590 QPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSG 649
+P++ + + GP + S + P V + + + Q+ S+ + K P G
Sbjct: 703 KPESNAVTKTAGP--IASAQKQPAGKVQI----VSKKVSYSHIQSKCGSKDNIKHVPGGG 756
Query: 650 KTPASIRKPPSSVKDADSGDK 670
+K S + G K
Sbjct: 757 NVQIQNKKVDISKVSSKCGSK 777
Score = 39.7 bits (91), Expect = 0.010
Identities = 41/194 (21%), Positives = 69/194 (35%), Gaps = 28/194 (14%)
Query: 288 LEQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVN-------MFQKQNSKPSVPVSIP 340
L +K ++ G+ + P PA P + P V ++ + PS P S P
Sbjct: 471 LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAP 530
Query: 341 KSKE--KQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAA------SSHPKLKSSKGIT 392
S+ K + A+++ S S + LP P A + K ++K +
Sbjct: 531 ASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVP 590
Query: 393 KKPQAPSNNASSSLASLNPVG-------------KNTSSPALPRTAPCISESPRKCISSP 439
P + ++SS+ + K T P+ P T P I + P S
Sbjct: 591 ADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSS 650
Query: 440 NTPKAKVIPAQNSA 453
TP+ + SA
Sbjct: 651 TTPRLSRLATNTSA 664
Score = 36.2 bits (82), Expect = 0.11
Identities = 80/335 (23%), Positives = 123/335 (36%), Gaps = 56/335 (16%)
Query: 364 LGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPR 423
L +S+ K+ + S S + K +AP + + +L + + LP
Sbjct: 277 LKEISLACKITELESVSLPTPEIQSDFLHSKVEAPPSEVADTLVIMTA----SKGVRLPE 332
Query: 424 TAPCISESPRKCI--SSPNTP-KAKVIPAQNSADLPESTLLPNKCSGKTQ--PKYL---- 474
I E+P+K S TP + K A+ + + P K G T PK
Sbjct: 333 PKDKILETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYMRPTKSRGLTPLLPKSTIQEQ 392
Query: 475 -KHNHISSRDNAVSHLAAH--SNSSSKCPKLPKANIPVRP----KPSFQSSAKMTKTS-S 526
+H + S A S + + P +P P KP + T TS +
Sbjct: 393 ERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKA 452
Query: 527 KTIATGLGTQSQPSD-GAPQAKPVP-AQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIV 584
KT T L Q P+ G KP+ A L A +P S+ + ++ K K I
Sbjct: 453 KTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIA 512
Query: 585 SATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKG 644
A K P+ +++ K P S+ +++ KS QTVAK+
Sbjct: 513 DA--KAPEKRASPSK-------------------PASAPASRSGSKSTQTVAKTT----- 546
Query: 645 PPRSGKTPASIRKP-PSSVKDADSGDKKPTAKKKE 678
T A++ PSS + KKPTA K E
Sbjct: 547 ------TAAAVASTGPSSRSPSTLLPKKPTAIKTE 575
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,260,276
Number of Sequences: 37866
Number of extensions: 1641836
Number of successful extensions: 8770
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 742
Number of HSP's that attempted gapping in prelim test: 6709
Number of HSP's gapped (non-prelim): 2194
length of query: 694
length of database: 18,247,518
effective HSP length: 109
effective length of query: 585
effective length of database: 14,120,124
effective search space: 8260272540
effective search space used: 8260272540
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.