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Search of human proteins with 27886557
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27886557 msh homeobox 2 [Homo sapiens]
(267 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27886557 msh homeobox 2 [Homo sapiens] 538 e-153
gi|118582284 msh homeobox 1 [Homo sapiens] 268 5e-72
gi|4885187 distal-less homeobox 5 [Homo sapiens] 96 4e-20
gi|14149728 BarH-like homeobox 1 [Homo sapiens] 92 4e-19
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 86 3e-17
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap... 86 3e-17
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap... 84 1e-16
gi|157743259 H6 family homeobox 3 [Homo sapiens] 83 3e-16
gi|39930383 BarH-like homeobox 2 [Homo sapiens] 83 3e-16
gi|4885185 distal-less homeobox 3 [Homo sapiens] 82 6e-16
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens] 82 6e-16
gi|4758168 distal-less homeobox 2 [Homo sapiens] 80 2e-15
gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens] 80 2e-15
gi|116805350 homeo box (H6 family) 1 [Homo sapiens] 80 2e-15
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens] 79 5e-15
gi|82659115 distal-less homeobox 6 [Homo sapiens] 78 7e-15
gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens] 78 7e-15
gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens] 78 7e-15
gi|70608170 H6 family homeobox 2 [Homo sapiens] 78 9e-15
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens] 78 9e-15
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 77 1e-14
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens] 77 2e-14
gi|153218470 BarH-like homeobox 1 [Homo sapiens] 77 2e-14
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 77 2e-14
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens] 77 2e-14
gi|226437602 NK1 homeobox 2 [Homo sapiens] 76 3e-14
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens] 76 3e-14
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens] 76 3e-14
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens] 76 3e-14
gi|89257348 homeo box HB9 [Homo sapiens] 76 3e-14
>gi|27886557 msh homeobox 2 [Homo sapiens]
Length = 267
Score = 538 bits (1386), Expect = e-153
Identities = 267/267 (100%), Positives = 267/267 (100%)
Query: 1 MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPK 60
MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPK
Sbjct: 1 MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPK 60
Query: 61 EASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPG 120
EASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPG
Sbjct: 61 EASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPG 120
Query: 121 RYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLN 180
RYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLN
Sbjct: 121 RYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLN 180
Query: 181 LTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASY 240
LTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASY
Sbjct: 181 LTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASY 240
Query: 241 PFHRPVLPIPPVGLYATPVGYGMYHLS 267
PFHRPVLPIPPVGLYATPVGYGMYHLS
Sbjct: 241 PFHRPVLPIPPVGLYATPVGYGMYHLS 267
>gi|118582284 msh homeobox 1 [Homo sapiens]
Length = 303
Score = 268 bits (684), Expect = 5e-72
Identities = 161/275 (58%), Positives = 189/275 (68%), Gaps = 25/275 (9%)
Query: 16 EGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPP--KEASPLPAESA-SA 72
+ P+ A G E A+ + V S LPFSVEALM+D + P KE++ P+E +A
Sbjct: 31 QAPSAAAATAAAMGADEEGAKPK-VSPSLLPFSVEALMADHRKPGAKESALAPSEGVQAA 89
Query: 73 GATLRPLLL--SGHGAREAHSP---------GPLVKPFETASVKSENSE--DGAAWMQEP 119
G + +PL + GA +A S G L+K E A VK+E+ E + WMQ P
Sbjct: 90 GGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSP 149
Query: 120 GRYSPPP-RHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSS 178
R+SPPP R +SP CTLRKHKTNRKPRTPFTT+QLLALERKFRQKQYLSIAERAEFSSS
Sbjct: 150 -RFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSS 208
Query: 179 LNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPML-PSSFSLPFPISSP-----LQA 232
L+LTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPML P++F L FP+ P
Sbjct: 209 LSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAG 268
Query: 233 ASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS 267
AS+YGAS PF R LP+ PVGLY VGY MYHL+
Sbjct: 269 ASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT 303
>gi|4885187 distal-less homeobox 5 [Homo sapiens]
Length = 289
Score = 95.5 bits (236), Expect = 4e-20
Identities = 65/194 (33%), Positives = 98/194 (50%), Gaps = 7/194 (3%)
Query: 14 DEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASP---LPAESA 70
D P++ +G P A + +LP S A SD P +P SA
Sbjct: 6 DRRVPSIRSGDFQAPFQTSAAMHHPSQESPTLPES-SATDSDYYSPTGGAPHGYCSPTSA 64
Query: 71 SAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHMS 130
S G L P HG + P K + S S + G A+ + P + P + ++
Sbjct: 65 SYGKALNPYQYQYHGVNGSAGSYP-AKAYADYSYASSYHQYGGAYNRVPSATNQPEKEVT 123
Query: 131 PTTCTL--RKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKI 188
+ K K RKPRT +++ QL AL+R+F++ QYL++ ERAE ++SL LT+TQVKI
Sbjct: 124 EPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKI 183
Query: 189 WFQNRRAKAKRLQE 202
WFQN+R+K K++ +
Sbjct: 184 WFQNKRSKIKKIMK 197
>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
Length = 327
Score = 92.4 bits (228), Expect = 4e-19
Identities = 89/263 (33%), Positives = 117/263 (44%), Gaps = 38/263 (14%)
Query: 5 SKGNDLFSPDEEGPAVVAGPGPG----PGGAEGAAEERRVKVSSLPFSVEALMSDKKPPK 60
S G D P +GPG PG A+ R V S F + +++D KP
Sbjct: 53 SPGRDCLETGTPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSS---FLIRDILADCKPLA 109
Query: 61 EASPLPAESASAGATLRPLLLSGHGAREAHS-PGPLVKPFETASVKSENS--EDGAAWMQ 117
+P +S+G P A+ A L K AS SE E+G +
Sbjct: 110 ACAPY----SSSGQPAAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREIS 165
Query: 118 EPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSS 177
R SPP R P RK RT FT QL LER F +++YLS+ +R E ++
Sbjct: 166 S-SRDSPPVRLKKP-----------RKARTAFTDHQLAQLERSFERQKYLSVQDRMELAA 213
Query: 178 SLNLTETQVKIWFQNRRAKAKRLQEAELEKLK-----MAAKPMLPSSFSLPFPISSPLQ- 231
SLNLT+TQVK W+QNRR K KR LE L A + M PS + P + S L
Sbjct: 214 SLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDP 273
Query: 232 AASIY---GASYP---FHRPVLP 248
A++Y G S P RP++P
Sbjct: 274 GAALYLYRGPSAPPPALQRPLVP 296
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 85.9 bits (211), Expect = 3e-17
Identities = 63/193 (32%), Positives = 88/193 (45%), Gaps = 8/193 (4%)
Query: 48 SVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGA-REAHSPGPLVKPFETASVKS 106
S+EA++ K PAE + GA R L A +A G P +
Sbjct: 34 SIEAILGFTKDDGILGTFPAERGARGAKERDRRLGARPACPKAPEEGSEPSPPPAPAPAP 93
Query: 107 ENSEDGAAWMQEPGRYSPPPR-HMSPTTCTLR------KHKTNRKPRTPFTTSQLLALER 159
E +EPG P P + P T + K +R+ RT FTT QL LER
Sbjct: 94 EYEAPRPYCPKEPGEARPSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELER 153
Query: 160 KFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSS 219
F + Y + R E + +NL E +V++WFQNRRAK +R ++ E+ +K+ P+L S
Sbjct: 154 AFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFS 213
Query: 220 FSLPFPISSPLQA 232
S P SPL A
Sbjct: 214 RSPPSATLSPLGA 226
>gi|210147470 NK2 transcription factor related, locus 6 [Homo
sapiens]
Length = 219
Score = 85.9 bits (211), Expect = 3e-17
Identities = 53/132 (40%), Positives = 75/132 (56%), Gaps = 11/132 (8%)
Query: 138 KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKA 197
K + RKPR F+ +Q+LALER+F+Q++YLS ER +S+L LT TQVKIWFQNRR K
Sbjct: 46 KARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKC 105
Query: 198 KRLQEAELEKLKMAAKPMLPSSFSLPF------PISSPLQAASIYGASYPFHRPVLPIPP 251
KR + + + L++A P+ P ++P P P A + + P+ V P
Sbjct: 106 KR--QRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPS--PYSAAVSPYSC 161
Query: 252 VGLYA-TPVGYG 262
G Y+ P G G
Sbjct: 162 YGGYSGAPYGAG 173
>gi|148746211 NK2 transcription factor related, locus 3 [Homo
sapiens]
Length = 364
Score = 84.3 bits (207), Expect = 1e-16
Identities = 48/109 (44%), Positives = 66/109 (60%), Gaps = 8/109 (7%)
Query: 138 KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKA 197
K ++ RKPR F+ +Q+ LER+F+Q++YLS ER +SSL LT TQVKIWFQNRR K
Sbjct: 144 KPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKC 203
Query: 198 KRLQEAELEKLKMAAKPMLPSSFSLPF------PISSPLQAASIYGASY 240
KR ++ + +L A P P ++P P +P +A YGA Y
Sbjct: 204 KRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKPCVTP--SAQAYGAPY 250
>gi|157743259 H6 family homeobox 3 [Homo sapiens]
Length = 357
Score = 82.8 bits (203), Expect = 3e-16
Identities = 91/295 (30%), Positives = 122/295 (41%), Gaps = 47/295 (15%)
Query: 10 LFSPDEEGPAVVAGPGPGPGGA-EGAAEERRVKVSSLPF----------SVEALMSDKKP 58
LF+P A A GA EGAA +V L F ++ A ++ P
Sbjct: 55 LFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLERSP 114
Query: 59 ----PKEASP----LPAESASAGATLRPLLLSGHGAREAHSPGPLVK------------P 98
P +P LP AS A LR S + SP PL+K P
Sbjct: 115 AWWYPYTLTPAGGHLPRPEASEKALLRDS--SPASGTDRDSPEPLLKADPDHKELDSKSP 172
Query: 99 FETASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHK-----------TNRKPRT 147
E +S++ E PG + T K +K RT
Sbjct: 173 DEIILEESDSEESKKEGEAAPGAAGASVGAAAATPGAEDWKKGAESPEKKPACRKKKTRT 232
Query: 148 PFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEK 207
F+ SQ+ LE F K+YLS +ERA ++SL+LTETQVKIWFQNRR K KR AELE
Sbjct: 233 VFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEA 292
Query: 208 LKM---AAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPV 259
+ AA+ ++ ++ AA+ GA P +P+L P Y+ PV
Sbjct: 293 ANLSHAAAQRIVRVPILYHENSAAEGAAAAAAGAPVPVSQPLLTFPHPVYYSHPV 347
>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
Length = 387
Score = 82.8 bits (203), Expect = 3e-16
Identities = 70/253 (27%), Positives = 110/253 (43%), Gaps = 29/253 (11%)
Query: 13 PDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESASA 72
P ++ P P P P G+A + S+ F ++ ++ D KP +P +S
Sbjct: 109 PQQQQPLPPQQPPPPPPQQLGSAASAP-RTSTSSFLIKDILGDSKPLAACAPYSTSVSSP 167
Query: 73 GATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAW--MQEPG-------RYS 123
T + + E+ P + +T K E+S+ +E G R S
Sbjct: 168 HHTPKQ---ESNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRES 224
Query: 124 PPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTE 183
PP R P RK RT F+ QL LER F +++YLS+ +R + +++LNLT+
Sbjct: 225 PPVRAKKP-----------RKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTD 273
Query: 184 TQVKIWFQNRRAKAKRLQEAELEKLK-----MAAKPMLPSSFSLPFPISSPLQAASIYGA 238
TQVK W+QNRR K KR LE L A + M PS + + + + + A
Sbjct: 274 TQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAA 333
Query: 239 SYPFHRPVLPIPP 251
+ + + PP
Sbjct: 334 AAAMYSSMYRTPP 346
>gi|4885185 distal-less homeobox 3 [Homo sapiens]
Length = 287
Score = 81.6 bits (200), Expect = 6e-16
Identities = 51/121 (42%), Positives = 73/121 (60%), Gaps = 4/121 (3%)
Query: 138 KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKA 197
K K RKPRT +++ QL AL+R+F++ QYL++ ERAE ++ L LT+TQVKIWFQNRR+K
Sbjct: 125 KPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKF 184
Query: 198 KRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYAT 257
K+L + ++ + P S + P S L S + P R LP PP+ A+
Sbjct: 185 KKLYKN--GEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAP-ARSQLP-PPLPYSAS 240
Query: 258 P 258
P
Sbjct: 241 P 241
>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
Length = 324
Score = 81.6 bits (200), Expect = 6e-16
Identities = 75/250 (30%), Positives = 105/250 (42%), Gaps = 38/250 (15%)
Query: 46 PFSVEALMSDKKPPKEASPLPAESASAGATLRPLLL-------SGHGAREAHSPGPLVKP 98
PFSV+ +++ ++ + + SA ATL P + EA +PG
Sbjct: 11 PFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPELR 70
Query: 99 FETASVKSEN---SEDGAAWMQEPGRYSPP-----PRHMSPTTCTLRKH----------- 139
E S S AA P YS P PR C L+K
Sbjct: 71 AELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNA 130
Query: 140 -----KTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRR 194
+ RKPR F+ +Q+ LER+F+Q++YLS ER + +S L LT TQVKIWFQNRR
Sbjct: 131 ERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRR 190
Query: 195 AKAKRLQEAELEKLKMAAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGL 254
K KR ++ + +L P P + + P+ G S P+ P G+
Sbjct: 191 YKCKRQRQDQTLELVGLPPPPPPPARRIAVPV-LVRDGKPCLGDSAPY------APAYGV 243
Query: 255 YATPVGYGMY 264
P GY Y
Sbjct: 244 GLNPYGYNAY 253
>gi|4758168 distal-less homeobox 2 [Homo sapiens]
Length = 328
Score = 80.1 bits (196), Expect = 2e-15
Identities = 40/83 (48%), Positives = 57/83 (68%), Gaps = 1/83 (1%)
Query: 119 PGRYSPPPRHMSPTTCTLR-KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSS 177
P P + P + K K RKPRT +++ QL AL+R+F++ QYL++ ERAE ++
Sbjct: 128 PANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAA 187
Query: 178 SLNLTETQVKIWFQNRRAKAKRL 200
SL LT+TQVKIWFQNRR+K K++
Sbjct: 188 SLGLTQTQVKIWFQNRRSKFKKM 210
>gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
Length = 255
Score = 80.1 bits (196), Expect = 2e-15
Identities = 38/65 (58%), Positives = 52/65 (80%)
Query: 138 KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKA 197
K K RKPRT +++ QL AL R+F+Q QYL++ ERAE ++SL LT+TQVKIWFQN+R+K
Sbjct: 124 KGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKF 183
Query: 198 KRLQE 202
K+L +
Sbjct: 184 KKLMK 188
>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
Length = 348
Score = 79.7 bits (195), Expect = 2e-15
Identities = 53/112 (47%), Positives = 65/112 (58%), Gaps = 4/112 (3%)
Query: 143 RKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQE 202
+K RT F+ SQ+ LE F K+YLS AERA ++SL LTETQVKIWFQNRR K KR
Sbjct: 204 KKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLA 263
Query: 203 AELEKLKMAAKPMLPSSFSLP--FPISSPLQAASIYGASYPFH-RPVLPIPP 251
AELE + + P +P + S P AA+ A+ PF P P PP
Sbjct: 264 AELEAASL-SPPGAQRLVRVPVLYHESPPAAAAAGPPATLPFPLAPAAPAPP 314
>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
Length = 411
Score = 78.6 bits (192), Expect = 5e-15
Identities = 72/212 (33%), Positives = 92/212 (43%), Gaps = 23/212 (10%)
Query: 2 ASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKE 61
A P D F E G G GG +A+ +P E D+ P E
Sbjct: 114 AEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSG----DEVPDD-EDDDEDEAPETE 168
Query: 62 ASPLPAESASAGATLRPLLLSGHGAREAH-SPGPLVK------PFETASVKSENSEDGAA 114
A+ E+ G L GA E SPG V P E + V ++ GAA
Sbjct: 169 AARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSPV-AQGPPGGAA 227
Query: 115 WMQEPGRYSPPPRHMSPTTCTLRKHKTN-------RKPRTPFTTSQLLALERKFRQKQYL 167
PG P+ + RK + R+ RT FT QL+ALE KF+ +YL
Sbjct: 228 ---APGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYL 284
Query: 168 SIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199
S+ ER + SL+LTETQVKIWFQNRR K K+
Sbjct: 285 SVCERLNLALSLSLTETQVKIWFQNRRTKWKK 316
>gi|82659115 distal-less homeobox 6 [Homo sapiens]
Length = 265
Score = 78.2 bits (191), Expect = 7e-15
Identities = 48/110 (43%), Positives = 72/110 (65%), Gaps = 8/110 (7%)
Query: 138 KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKA 197
K K RKPRT +++ QL AL +F+Q QYL++ ERAE ++SL LT+TQVKIWFQN+R+K
Sbjct: 135 KGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKF 194
Query: 198 KRLQEA-----ELEKLKMAAKPMLPSSFSLP--FPISSPLQAASIYGASY 240
K+L + E + L+ +A + P S +LP + +S+ + S+ SY
Sbjct: 195 KKLLKQGSNPHESDPLQGSA-ALSPRSPALPPVWDVSASAKGVSMPPNSY 243
>gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]
Length = 240
Score = 78.2 bits (191), Expect = 7e-15
Identities = 51/137 (37%), Positives = 72/137 (52%), Gaps = 15/137 (10%)
Query: 118 EPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSS 177
E R SP P P K RKPRT +++ QL L ++F+ QYL++ ERA+ ++
Sbjct: 97 EKPRLSPEPSERRPQAPA----KKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAA 152
Query: 178 SLNLTETQVKIWFQNRRAKAKRL-------QEAELEKLKMAAKPM---LPSSFSLPFPIS 227
L LT+TQVKIWFQN+R+K K+L QE + + P LPS + LP +
Sbjct: 153 QLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGT 212
Query: 228 SPLQA-ASIYGASYPFH 243
P + +GA Y H
Sbjct: 213 LPTSGYGNSFGAWYQHH 229
>gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens]
Length = 168
Score = 78.2 bits (191), Expect = 7e-15
Identities = 51/137 (37%), Positives = 72/137 (52%), Gaps = 15/137 (10%)
Query: 118 EPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSS 177
E R SP P P K RKPRT +++ QL L ++F+ QYL++ ERA+ ++
Sbjct: 25 EKPRLSPEPSERRPQAPA----KKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAA 80
Query: 178 SLNLTETQVKIWFQNRRAKAKRL-------QEAELEKLKMAAKPM---LPSSFSLPFPIS 227
L LT+TQVKIWFQN+R+K K+L QE + + P LPS + LP +
Sbjct: 81 QLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGT 140
Query: 228 SPLQA-ASIYGASYPFH 243
P + +GA Y H
Sbjct: 141 LPTSGYGNSFGAWYQHH 157
>gi|70608170 H6 family homeobox 2 [Homo sapiens]
Length = 273
Score = 77.8 bits (190), Expect = 9e-15
Identities = 56/124 (45%), Positives = 68/124 (54%), Gaps = 5/124 (4%)
Query: 143 RKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQE 202
+K RT F+ SQ+ LE F K+YLS +ERA +SSL LTETQVK WFQNRR K KR
Sbjct: 150 KKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLS 209
Query: 203 AELEKLKMA-AKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGY 261
AELE MA A S L F SS L+ ++P L P L A P+ Y
Sbjct: 210 AELEAANMAHASAQTLVSMPLVFRDSSLLRVPVPRSLAFP---APLYYPGSNLSALPL-Y 265
Query: 262 GMYH 265
+Y+
Sbjct: 266 NLYN 269
>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
Length = 348
Score = 77.8 bits (190), Expect = 9e-15
Identities = 44/113 (38%), Positives = 66/113 (58%), Gaps = 8/113 (7%)
Query: 117 QEPGRY---SPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERA 173
++PG +PP + +T + K NR+ RT FT+ QLL LE++F K+YLS+ ER+
Sbjct: 222 EDPGHALEETPPSSGAAGSTTSTGK---NRRRRTAFTSEQLLELEKEFHCKKYLSLTERS 278
Query: 174 EFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFSLPFPI 226
+ + +L L+E QVKIWFQNRRAK KR++ +P +P P+
Sbjct: 279 QIAHALKLSEVQVKIWFQNRRAKWKRVKAGNAN--SKTGEPSRNPKIVVPIPV 329
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 77.4 bits (189), Expect = 1e-14
Identities = 72/212 (33%), Positives = 91/212 (42%), Gaps = 23/212 (10%)
Query: 2 ASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKE 61
A P D F E G G GG +A+ +P E D+ P E
Sbjct: 517 AEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSG----DEVPDD-EDDDEDEAPETE 571
Query: 62 ASPLPAESASAGATLRPLLLSGHGAREAH-SPGPLVK------PFETASVKSENSEDGAA 114
A+ E+ G L GA E SPG V P E + V + GAA
Sbjct: 572 AARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSPV-APGPPGGAA 630
Query: 115 WMQEPGRYSPPPRHMSPTTCTLRKHKTN-------RKPRTPFTTSQLLALERKFRQKQYL 167
PG P+ + RK + R+ RT FT QL+ALE KF+ +YL
Sbjct: 631 ---APGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYL 687
Query: 168 SIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199
S+ ER + SL+LTETQVKIWFQNRR K K+
Sbjct: 688 SVCERLNLALSLSLTETQVKIWFQNRRTKWKK 719
Score = 29.3 bits (64), Expect = 3.8
Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 12/79 (15%)
Query: 55 DKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAA 114
+K+P E+ LP++ ++G L +P P+V P A+ +S E G
Sbjct: 87 EKEPRPESRGLPSDFPNSGVFL-----------PTPTPKPIVTPPGPAAGESSAME-GMF 134
Query: 115 WMQEPGRYSPPPRHMSPTT 133
+ GR SPPP +SP +
Sbjct: 135 PVHWAGRGSPPPALISPAS 153
>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 653
Score = 76.6 bits (187), Expect = 2e-14
Identities = 54/148 (36%), Positives = 71/148 (47%), Gaps = 15/148 (10%)
Query: 59 PKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQE 118
P+ A+P + + A LRP + PGP S + GAA
Sbjct: 15 PRGATPTCTPAQPSWARLRPTRPPEPPSTRQRPPGP-----RENSPVAPGPPGGAA---A 66
Query: 119 PGRYSPPPRHMSPTTCTLRKHKTN-------RKPRTPFTTSQLLALERKFRQKQYLSIAE 171
PG P+ + RK + R+ RT FT QL+ALE KF+ +YLS+ E
Sbjct: 67 PGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCE 126
Query: 172 RAEFSSSLNLTETQVKIWFQNRRAKAKR 199
R + SL+LTETQVKIWFQNRR K K+
Sbjct: 127 RLNLALSLSLTETQVKIWFQNRRTKWKK 154
>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
Length = 254
Score = 76.6 bits (187), Expect = 2e-14
Identities = 61/194 (31%), Positives = 96/194 (49%), Gaps = 28/194 (14%)
Query: 29 GGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGARE 88
G EG A+ R + S F +E ++++ PK A+P A +A+AG L+ + + AR
Sbjct: 13 GPPEGCADHRPHRYRS--FMIEEILTEPPGPKGAAPAAA-AAAAGELLKFGVQALLAARP 69
Query: 89 AHSPGPLVKPFETASVKSENSEDGAAWMQE---------PGRYSPPPRHMSPTTCTLR-- 137
HS ++K + A K + G + + PG P H+ P LR
Sbjct: 70 FHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLAAGPGLPGAAGAP--HL-PLELQLRGK 126
Query: 138 -----------KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQV 186
K K R+ RT FT QL+ LE++F +++YLS +R + + SL L++ QV
Sbjct: 127 LEAAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQV 186
Query: 187 KIWFQNRRAKAKRL 200
K W+QNRR K K++
Sbjct: 187 KTWYQNRRMKWKKI 200
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 76.6 bits (187), Expect = 2e-14
Identities = 37/85 (43%), Positives = 57/85 (67%), Gaps = 2/85 (2%)
Query: 142 NRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQ 201
+R+ RT FT+ QLL LE++F K+YLS+ ER++ + +L L+E QVKIWFQNRRAK KR++
Sbjct: 261 SRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIK 320
Query: 202 EAELEKLKMAAKPMLPSSFSLPFPI 226
+ + +P+ +P P+
Sbjct: 321 AGNVS--SRSGEPVRNPKIVVPIPV 343
>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
Length = 284
Score = 76.6 bits (187), Expect = 2e-14
Identities = 63/195 (32%), Positives = 92/195 (47%), Gaps = 31/195 (15%)
Query: 58 PPKEASPLPAESA-SAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAA-- 114
P +PLP S G +R AH P P+ P A S G A
Sbjct: 62 PAGSLAPLPGSSGVGPGGVIRV---------PAHRPLPVPPPAGGAPAVPGPSGLGGAGG 112
Query: 115 -------WMQEPGRYSPP--PRHMSPTTCTLR-----KHKT---NRKPRTPFTTSQLLAL 157
WM R++ +SP + T R +++T +KPRT F+ SQ+L L
Sbjct: 113 LAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLEL 172
Query: 158 ERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR--LQEAELEKLKMAAKPM 215
ER+F +++YL+ AERA + +L +T+ QVK WFQNRR K +R +E E E+ + +
Sbjct: 173 ERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLL 232
Query: 216 LPSSFSLPFPISSPL 230
+LP P+ PL
Sbjct: 233 HLQQDALPRPLRPPL 247
>gi|226437602 NK1 homeobox 2 [Homo sapiens]
Length = 310
Score = 76.3 bits (186), Expect = 3e-14
Identities = 50/101 (49%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 102 ASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRKPR---TPFTTSQLLALE 158
A E EDG P R SPP SP R KPR T FT QL+ALE
Sbjct: 124 ALASGEPCEDGGGG---PVR-SPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALE 179
Query: 159 RKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199
KFR +YLS+ ER + SL+LTETQVKIWFQNRR K K+
Sbjct: 180 NKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 220
>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 76.3 bits (186), Expect = 3e-14
Identities = 50/101 (49%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 102 ASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRKPR---TPFTTSQLLALE 158
A E EDG P R SPP SP R KPR T FT QL+ALE
Sbjct: 146 ALASGEPCEDGGGG---PVR-SPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALE 201
Query: 159 RKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199
KFR +YLS+ ER + SL+LTETQVKIWFQNRR K K+
Sbjct: 202 NKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 242
>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 76.3 bits (186), Expect = 3e-14
Identities = 50/101 (49%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 102 ASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRKPR---TPFTTSQLLALE 158
A E EDG P R SPP SP R KPR T FT QL+ALE
Sbjct: 146 ALASGEPCEDGGGG---PVR-SPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALE 201
Query: 159 RKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199
KFR +YLS+ ER + SL+LTETQVKIWFQNRR K K+
Sbjct: 202 NKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 242
>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 76.3 bits (186), Expect = 3e-14
Identities = 50/101 (49%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 102 ASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRKPR---TPFTTSQLLALE 158
A E EDG P R SPP SP R KPR T FT QL+ALE
Sbjct: 146 ALASGEPCEDGGGG---PVR-SPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALE 201
Query: 159 RKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199
KFR +YLS+ ER + SL+LTETQVKIWFQNRR K K+
Sbjct: 202 NKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK 242
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 76.3 bits (186), Expect = 3e-14
Identities = 39/71 (54%), Positives = 52/71 (73%)
Query: 143 RKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQE 202
R+PRT FT+ QLL LE +F+ +YLS +R E ++SL LTETQVKIWFQNRR K KR ++
Sbjct: 242 RRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKK 301
Query: 203 AELEKLKMAAK 213
A+ + + A K
Sbjct: 302 AKEQAAQEAEK 312
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,166,498
Number of Sequences: 37866
Number of extensions: 725592
Number of successful extensions: 4262
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 292
Number of HSP's successfully gapped in prelim test: 207
Number of HSP's that attempted gapping in prelim test: 3662
Number of HSP's gapped (non-prelim): 765
length of query: 267
length of database: 18,247,518
effective HSP length: 100
effective length of query: 167
effective length of database: 14,460,918
effective search space: 2414973306
effective search space used: 2414973306
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.