Guide to the Human Genome
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Search of human proteins with 27881494

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27881494 zonadhesin isoform 6 [Homo sapiens]
         (2721 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27881494 zonadhesin isoform 6 [Homo sapiens]                      5731   0.0  
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                      5472   0.0  
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]        866   0.0  
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ...   856   0.0  
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr...   686   0.0  
gi|134268640 tectorin alpha precursor [Homo sapiens]                  654   0.0  
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr...   555   e-157
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]    366   e-100
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom...   324   8e-88
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom...   324   8e-88
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap...   324   8e-88
gi|116284392 mucin 2 precursor [Homo sapiens]                         298   6e-80
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr...   297   1e-79
gi|89191868 von Willebrand factor preproprotein [Homo sapiens]        290   1e-77
gi|134031945 SCO-spondin [Homo sapiens]                               286   2e-76
gi|161019170 mucin 5AC [Homo sapiens]                                 265   6e-70
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]      264   8e-70
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]             254   8e-67
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]             254   8e-67
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]             254   8e-67
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]             254   8e-67
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]             254   8e-67
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]             254   8e-67
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]   231   7e-60
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]             213   2e-54
gi|151301154 mucin 6, gastric [Homo sapiens]                          207   1e-52
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]            197   9e-50
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  192   4e-48
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  192   4e-48
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  192   4e-48

>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 5731 bits (14867), Expect = 0.0
 Identities = 2721/2721 (100%), Positives = 2721/2721 (100%)

Query: 1    MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD 60
            MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD
Sbjct: 1    MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD 60

Query: 61   EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA 120
            EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA
Sbjct: 61   EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA 120

Query: 121  HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG 180
            HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG
Sbjct: 121  HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG 180

Query: 181  TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS 240
            TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS
Sbjct: 181  TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS 240

Query: 241  GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG 300
            GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG
Sbjct: 241  GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG 300

Query: 301  AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA 360
            AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA
Sbjct: 301  AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA 360

Query: 361  TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY 420
            TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY
Sbjct: 361  TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY 420

Query: 421  IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL 480
            IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL
Sbjct: 421  IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL 480

Query: 481  WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP 540
            WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP
Sbjct: 481  WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP 540

Query: 541  ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600
            ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI
Sbjct: 541  ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 601  STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
            STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE
Sbjct: 601  STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660

Query: 661  PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
            PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP
Sbjct: 661  PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720

Query: 721  TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780
            TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP
Sbjct: 721  TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780

Query: 781  TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
            TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST
Sbjct: 781  TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840

Query: 841  EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT 900
            EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT
Sbjct: 841  EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT 900

Query: 901  IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
            IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE
Sbjct: 901  IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960

Query: 961  KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020
            KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH
Sbjct: 961  KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020

Query: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF 1080
            APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF
Sbjct: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF 1080

Query: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL 1140
            LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL
Sbjct: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL 1140

Query: 1141 KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN 1200
            KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN
Sbjct: 1141 KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN 1200

Query: 1201 EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ 1260
            EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ
Sbjct: 1201 EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ 1260

Query: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
            TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW
Sbjct: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320

Query: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS 1380
            QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS
Sbjct: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS 1380

Query: 1381 CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP 1440
            CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP
Sbjct: 1381 CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP 1440

Query: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
            DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC
Sbjct: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC 1500

Query: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560
            KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF
Sbjct: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560

Query: 1561 MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM 1620
            MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM
Sbjct: 1561 MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM 1620

Query: 1621 LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC 1680
            LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC
Sbjct: 1621 LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC 1680

Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK 1740
            GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK
Sbjct: 1681 GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK 1740

Query: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP 1800
            NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP
Sbjct: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP 1800

Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
            AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860

Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
            CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920

Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE 1980
            LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE 1980

Query: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK 2040
            GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK
Sbjct: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK 2040

Query: 2041 IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
            IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD
Sbjct: 2041 IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100

Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
            KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT
Sbjct: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160

Query: 2161 PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220
            PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC
Sbjct: 2161 PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220

Query: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG 2280
            LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG
Sbjct: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG 2280

Query: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
            KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL
Sbjct: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340

Query: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
            TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV
Sbjct: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400

Query: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY 2460
            QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY
Sbjct: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY 2460

Query: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
            EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG
Sbjct: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520

Query: 2521 AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA 2580
            AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA
Sbjct: 2521 AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA 2580

Query: 2581 QDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQNDGQCREQGATFT 2640
            QDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQNDGQCREQGATFT
Sbjct: 2581 QDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQNDGQCREQGATFT 2640

Query: 2641 CECEVGYGGGLCMEPRDAPPPRKPASNLVAVLLGLLVPVVVVLLAVTRECIYRTRRKREK 2700
            CECEVGYGGGLCMEPRDAPPPRKPASNLVAVLLGLLVPVVVVLLAVTRECIYRTRRKREK
Sbjct: 2641 CECEVGYGGGLCMEPRDAPPPRKPASNLVAVLLGLLVPVVVVLLAVTRECIYRTRRKREK 2700

Query: 2701 TQEGDRLARLVDTDTVLDCAC 2721
            TQEGDRLARLVDTDTVLDCAC
Sbjct: 2701 TQEGDRLARLVDTDTVLDCAC 2721


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 5472 bits (14196), Expect = 0.0
 Identities = 2596/2599 (99%), Positives = 2598/2599 (99%)

Query: 1    MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD 60
            MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD
Sbjct: 1    MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD 60

Query: 61   EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA 120
            EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA
Sbjct: 61   EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA 120

Query: 121  HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG 180
            HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG
Sbjct: 121  HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG 180

Query: 181  TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS 240
            TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS
Sbjct: 181  TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS 240

Query: 241  GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG 300
            GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG
Sbjct: 241  GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG 300

Query: 301  AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA 360
            AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA
Sbjct: 301  AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA 360

Query: 361  TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY 420
            TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY
Sbjct: 361  TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY 420

Query: 421  IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL 480
            IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL
Sbjct: 421  IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL 480

Query: 481  WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP 540
            WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP
Sbjct: 481  WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP 540

Query: 541  ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600
            ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI
Sbjct: 541  ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 601  STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
            STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE
Sbjct: 601  STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660

Query: 661  PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
            PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP
Sbjct: 661  PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720

Query: 721  TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780
            TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP
Sbjct: 721  TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780

Query: 781  TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
            TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST
Sbjct: 781  TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840

Query: 841  EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT 900
            EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT
Sbjct: 841  EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT 900

Query: 901  IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
            IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE
Sbjct: 901  IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960

Query: 961  KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020
            KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH
Sbjct: 961  KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020

Query: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF 1080
            APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF
Sbjct: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF 1080

Query: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL 1140
            LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL
Sbjct: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL 1140

Query: 1141 KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN 1200
            KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN
Sbjct: 1141 KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN 1200

Query: 1201 EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ 1260
            EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ
Sbjct: 1201 EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ 1260

Query: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
            TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW
Sbjct: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320

Query: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS 1380
            QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS
Sbjct: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS 1380

Query: 1381 CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP 1440
            CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP
Sbjct: 1381 CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP 1440

Query: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
            DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC
Sbjct: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC 1500

Query: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560
            KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF
Sbjct: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560

Query: 1561 MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM 1620
            MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM
Sbjct: 1561 MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM 1620

Query: 1621 LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC 1680
            LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC
Sbjct: 1621 LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC 1680

Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK 1740
            GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK
Sbjct: 1681 GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK 1740

Query: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP 1800
            NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP
Sbjct: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP 1800

Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
            AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860

Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
            CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920

Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE 1980
            LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE 1980

Query: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK 2040
            GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK
Sbjct: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK 2040

Query: 2041 IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
            IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD
Sbjct: 2041 IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100

Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
            KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT
Sbjct: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160

Query: 2161 PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220
            PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC
Sbjct: 2161 PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220

Query: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG 2280
            LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG
Sbjct: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG 2280

Query: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
            KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL
Sbjct: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340

Query: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
            TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV
Sbjct: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400

Query: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY 2460
            QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY
Sbjct: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY 2460

Query: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
            EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG
Sbjct: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520

Query: 2521 AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA 2580
            AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA
Sbjct: 2521 AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA 2580

Query: 2581 QDPREQEELRCQVLSGYAI 2599
            QDPREQEELRCQVLSG+ +
Sbjct: 2581 QDPREQEELRCQVLSGHGV 2599



 Score =  707 bits (1825), Expect = 0.0
 Identities = 433/1320 (32%), Positives = 644/1320 (48%), Gaps = 95/1320 (7%)

Query: 1044 CPPNARYESCA--CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN- 1098
            CPPN++Y  CA  CP +C S      C   C E C CNPGF+ S   CI  S C C +  
Sbjct: 1426 CPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPA 1485

Query: 1099 NDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
              Y++ G  W+ P C E C C   +R+ CQ  +C     C  ++G YGCH   G ATC  
Sbjct: 1486 GSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQ-GAATCTA 1544

Query: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQE-GVSCLSKVYV 1216
             GDPHY+TFDG    FMG CTY+L +PC   S D +F V+A NE +G    VS +  V+V
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHV 1604

Query: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQL 1275
            T+ + +++LL+G + ++ G +V LP   ++G V +  S   V L T FGL+VR+DG   +
Sbjct: 1605 TVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLV 1664

Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
             VTV S+Y G+LCGLCGNY+ NS +D+L+ D   AGD  +LG +W+  +  +  C  + V
Sbjct: 1665 EVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGC--FLV 1722

Query: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
               PS       + +    C  L++  GPF  C   V   S F SC+   CG +G    L
Sbjct: 1723 GGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTAL 1782

Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455
            C  +    + C  AG A   WR   FCPM CPP S YS C+ PCPDTC S  +   C   
Sbjct: 1783 CRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKA 1841

Query: 1456 --CVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPG-CKELCVCESNNRI 1512
              C E+CEC  G +LSG  C+P  QCGC  PAGSY  VGERWY    C  LC C  +N I
Sbjct: 1842 LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNI 1901

Query: 1513 RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC 1572
             C    C+  + C   DG+  C A G   C   G+ HY++FDG+ H     CT VL + C
Sbjct: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961

Query: 1573 WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632
                   +F +SA +E   G  E   +  V++ ++D  ++L +G +V++N  +V LP   
Sbjct: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAIS 2021

Query: 1633 AQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNL 1692
                V+++ SS   ++    G+QV++DG+HL+E+ +P++Y G++CG+CGN+N+   D+ +
Sbjct: 2022 QIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081

Query: 1693 RPDRKLAGDSMQLGAAWKLPESSEPGC--FLVGGK--PSSCQENSMAD--------AWNK 1740
             P  ++A    +   +WK  +  +P C   LV  +  P+  QEN   +        A  K
Sbjct: 2082 MPSDEVANSDSEFVNSWK-DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREK 2140

Query: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QA 1799
              A L  P   ++QC   +        C +  C   G   ALC++LQA+ + C   G + 
Sbjct: 2141 CEAALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKP 2198

Query: 1800 PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKA-LPCAESCECQKGHILSG 1858
            P WRN +FCP+ CP  SSY+ C   C  +C  ++   +  K    CAE C CQ G++LS 
Sbjct: 2199 PLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSE 2258

Query: 1859 TSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWAL- 1917
              CVP  QCGC D  G   P+G+ W +   CT  C C+    I C    C     C    
Sbjct: 2259 DKCVPRSQCGCKDAHGGSIPLGKSWVSSG-CTEKCVCT-GGAIQCGDFRCPSGSHCQLTS 2316

Query: 1918 -DGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCH--PAMALPFFKISA 1974
             +    C +     C + G+  Y++FDG ++ +    T VL+K     P    P   +  
Sbjct: 2317 DNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-VEG 2375

Query: 1975 KHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLP-AISQIPGVSVKSSSI 2033
            +++ +   +  F L EV   +Y  +V LQ G  +++N++++ +P   ++   V++    +
Sbjct: 2376 RNKMDPPRSSIF-LQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRL 2434

Query: 2034 YSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE 2093
            Y + + ++   V F G     I +P+ Y G V G+CGN++   ++++M+PS  +  + + 
Sbjct: 2435 YLVTDFEL--VVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNT 2492

Query: 2094 FVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPS----------GNCRAADLRRAREKCEA 2143
            F NSW+ K  D    +LL   + IPAE++   +            C    L     +   
Sbjct: 2493 FGNSWEVKTED----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACR 2548

Query: 2144 ALRAPV--WAQCASRIDLTPFLVDCANTLCEFGG---LYQALCQALQAFGATCQSQGLKP 2198
             L  P   +A C   +   PF   C   LC         +  CQ L   G + +      
Sbjct: 2549 VLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYH---- 2604

Query: 2199 PLWRNSSFCPLECPAYSSYTNCLPS--CSPSCWDLDGRCEGAKVPSACAEGCICQ-PGYV 2255
                            S   + LPS  C P      GR  G + P     G + Q P   
Sbjct: 2605 ---------------ISELYDTLPSILCQP------GRPRGLRGP---LRGRLRQHPRLC 2640

Query: 2256 LSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAI-QCGDFRCPSGSHCQL 2314
            L      P + CGC  ++G    LG S+++  C+++C C    I  C  F C +G  C L
Sbjct: 2641 LQWHPEPPLADCGCT-SNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTL 2699



 Score =  701 bits (1808), Expect = 0.0
 Identities = 407/1213 (33%), Positives = 606/1213 (49%), Gaps = 62/1213 (5%)

Query: 1426 CPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPA 1485
            CPPN++Y  CA  CP +C S      C   C E C CNPGF+ S   CI  S C C +  
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN- 1098

Query: 1486 GSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQ-GAATCTA 1544
              Y++ G  W+ P C E C C   +R+ CQ  +C     C  ++G YGCH   G ATC  
Sbjct: 1099 NDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158

Query: 1545 SGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHV 1604
             GDPHY+TFDG    FMG CTY+L +PC   S D +F V+A NE +G    VS +  V+V
Sbjct: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQE-GVSCLSKVYV 1216

Query: 1605 TVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLV 1664
            T+ + +++LL+G + ++ G +V LP   ++G V +  S   V L T FGL+VR+DG   +
Sbjct: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQL 1275

Query: 1665 EVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGC--FLV 1722
             VTV S+Y G+LCGLCGNY+ NS +D+L+ D   AGD  +LG +W+  +  +  C  + V
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335

Query: 1723 GGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTAL 1782
               PS       + +    C  L++  GPF  C   V   S F SC+   CG +G    L
Sbjct: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395

Query: 1783 CRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKA 1841
            C  +    + C  AG A   WR   FCPM CPP S YS C+ PCPDTC S  +   C   
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455

Query: 1842 LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNI 1901
              C E+CEC  G +LSG  C+P  QCGC  PAGSY  VGERWY    C  LC C  +N I
Sbjct: 1456 --CVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPG-CKELCVCESNNRI 1512

Query: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
             C    C+  + C   DG+  C A G   C   G+ HY++FDG+ H     CT VL + C
Sbjct: 1513 RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC 1572

Query: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAIS 2021
                   +F +SA +E   G  E   +  V++ ++D  ++L +G +V++N  +V LP   
Sbjct: 1573 WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632

Query: 2022 QIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081
                V+++ SS   ++    G+QV++DG+HL+E+ +P++Y G++CG+CGN+N+   D+ +
Sbjct: 1633 AQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNL 1692

Query: 2082 MPSDEVANSDSEFVNSWK-DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREK 2140
             P  ++A    +   +WK  +  +P C   LV  +  P+  QEN   +        A  K
Sbjct: 1693 RPDRKLAGDSMQLGAAWKLPESSEPGC--FLVGGK--PSSCQENSMAD--------AWNK 1740

Query: 2141 CEAALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKP 2198
              A L  P   ++QC   +        C +  C   G   ALC++LQA+ + C   G + 
Sbjct: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QA 1799

Query: 2199 PLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSE 2258
            P WRN +FCP+ CP  SSY+ C   C  +C  ++   +  K    CAE C CQ G++LS 
Sbjct: 1800 PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKA-LPCAESCECQKGHILSG 1858

Query: 2259 DKCVPRSQCGCKDAHGGSIPLGKSWVSSG-CTEKCVCT-GGAIQCGDFRCPSGSHCQLTS 2316
              CVP  QCGC D  G   P+G+ W +   CT  C C+    I C    C     C    
Sbjct: 1859 TSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWAL- 1917

Query: 2317 DNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-VEG 2375
             +    C +     C + G+  Y++FDG ++ +    T VL+K     P    P   +  
Sbjct: 1918 -DGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCH--PAMALPFFKISA 1974

Query: 2376 RNKMDPPRSSIF-LQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRL 2434
            +++ +   +  F L EV   +Y  +V LQ G  +++N++++ +P   ++   V++    +
Sbjct: 1975 KHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLP-AISQIPGVSVKSSSI 2033

Query: 2435 YLVTDFEL--VVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNT 2492
            Y + + ++   V F G     I +P+ Y G V G+CGN++   ++++M+PS  +  + + 
Sbjct: 2034 YSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE 2093

Query: 2493 FGNSWEVKTED----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACR 2548
            F NSW+ K  D    +LL   + IPAE++   +            C    L     +   
Sbjct: 2094 FVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPS----------GNCRAADLRRAREKCEA 2143

Query: 2549 VLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAAL 2608
             L  P   +A C   +   PF   C   LC         +  CQ L  +   CQ  G   
Sbjct: 2144 ALRAPV--WAQCASRIDLTPFLVDCANTLCEFGG---LYQALCQALQAFGATCQSQGLKP 2198

Query: 2609 AGWRDRTLCESPC 2621
              WR+ + C   C
Sbjct: 2199 PLWRNSSFCPLEC 2211



 Score =  405 bits (1040), Expect = e-112
 Identities = 267/917 (29%), Positives = 402/917 (43%), Gaps = 75/917 (8%)

Query: 1043 RCPPNARYESCA--CPASCKS---PR--PSCGPLCREGCVCNPGFLFSDNHCIQASSCNC 1095
            RCPP + Y  C+  CP +C S   PR  P   P C E C C  G + S   C+    C C
Sbjct: 1811 RCPPGSSYSPCSSPCPDTCSSINNPRDCPKALP-CAESCECQKGHILSGTSCVPLGQCGC 1869

Query: 1096 FYNNDYYEP-GAEWFSPN-CTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGT 1153
                  Y P G  W++ N CT  C C   + + C  S C  + +C   +G   C   +G 
Sbjct: 1870 TDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRA-SGV 1928

Query: 1154 ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTD-PFFRVTAKNE-EQGQEGVSCL 1211
              C + G+ HYV+FDG +      CT +L + C  +   PFF+++AK+E E+G      L
Sbjct: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988

Query: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS-KGVFLGASGRFVELQTEFGLRVRWD 1270
             +VY+ + ++ VTL KG R L+  +QVTLPAI    GV + +S  +  +  + G++V++D
Sbjct: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048

Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
            G+  L + + +TY GK+CG+CGN++   +++ +      A    E  NSW+ D+D D  C
Sbjct: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK-DKDIDPSC 2107

Query: 1331 QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFET---------CLLHVKAASFFDSC 1381
            Q   +V+     +  Q + SG      L       E          C   +    F   C
Sbjct: 2108 QSL-LVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDC 2166

Query: 1382 MLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPD 1441
               +C F GL   LC  +     TCQ  G     WR   FCP+ CP  S Y+ C   C  
Sbjct: 2167 ANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSP 2226

Query: 1442 TC---HSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKP 1498
            +C        G      C E C C PG+VLS  +C+PRSQCGC    G    +G+ W   
Sbjct: 2227 SCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSS 2286

Query: 1499 GCKELCVCESNNRIRCQPWRCRAQEFCG--QQDGIYGCHAQGAATCTASGDPHYLTFDGA 1556
            GC E CVC +   I+C  +RC +   C     +    C +  +  C+  GDP YLTFDG 
Sbjct: 2287 GCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGF 2345

Query: 1557 LHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRG 1616
             +   G  TYVL +      +    ++              +++ V  TV+   + L  G
Sbjct: 2346 SYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAG 2405

Query: 1617 CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQL 1676
             ++++N  ++A+P +     + + L    + L T+F L V + G     +++PS Y G +
Sbjct: 2406 LELVVNNQKMAVP-YRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLV 2464

Query: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLP--------------ESSEPGCFL- 1721
             GLCGNY+ N  +D + P   L  +    G +W++               E    G  L 
Sbjct: 2465 SGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELG 2524

Query: 1722 --VGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDT 1779
               G + S C    +A    + C +L +PQGPF+ CHQ V P+     CV   C      
Sbjct: 2525 LRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC------ 2578

Query: 1780 TALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP 1839
                            + Q P  +    C +    G S     S   DT  SI      P
Sbjct: 2579 ----------------SAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRP 2622

Query: 1840 KAL--PCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSV 1897
            + L  P            L      PL  CGCT   G Y+ +G  + TE+ C++ CTC+ 
Sbjct: 2623 RGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSN-GIYYQLGSSFLTED-CSQRCTCAS 2680

Query: 1898 HNNITCFQSTCKPNQIC 1914
               + C   +C+  ++C
Sbjct: 2681 SRILLCEPFSCRAGEVC 2697



 Score =  223 bits (567), Expect = 3e-57
 Identities = 112/138 (81%), Positives = 114/138 (82%), Gaps = 6/138 (4%)

Query: 2590 RCQVLSGYAILCQ----EAG--AALAGWRDRTLCESPCLQNPCQNDGQCREQGATFTCEC 2643
            RC   S   +LC+     AG    L         ESPCLQNPCQNDGQCREQGATFTCEC
Sbjct: 2675 RCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCREQGATFTCEC 2734

Query: 2644 EVGYGGGLCMEPRDAPPPRKPASNLVAVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQE 2703
            EVGYGGGLCMEPRDAPPPRKPASNLVAVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQE
Sbjct: 2735 EVGYGGGLCMEPRDAPPPRKPASNLVAVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQE 2794

Query: 2704 GDRLARLVDTDTVLDCAC 2721
            GDRLARLVDTDTVLDCAC
Sbjct: 2795 GDRLARLVDTDTVLDCAC 2812



 Score =  183 bits (465), Expect = 2e-45
 Identities = 141/522 (27%), Positives = 217/522 (41%), Gaps = 57/522 (10%)

Query: 1044 CPPNARYESC--ACPASCKSPRPSCG-----PLCREGCVCNPGFLFSDNHCIQASSCNCF 1096
            CP  + Y +C  +C  SC      C        C EGC+C PG++ S++ C+  S C C 
Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCK 2270

Query: 1097 YNNDYYEP-GAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTAT 1155
              +    P G  W S  CTE C C  G  ++C   +C + + CQL +     +  +  + 
Sbjct: 2271 DAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329

Query: 1156 -CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG---NSTDPFFRVTAKNEEQGQEGVSCL 1211
             C VYGDP Y+TFDG  +   G+ TY+L +         +P   V  +N+         L
Sbjct: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-VEGRNKMDPPRSSIFL 2388

Query: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271
             +V  T+    V L  G   +V  Q++ +P  P++ + +   G+ + L T+F L V + G
Sbjct: 2389 QEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGG 2448

Query: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDE----- 1326
             +   +++ S Y G + GLCGNYD N  ND +   G+   +    GNSW+   ++     
Sbjct: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508

Query: 1327 ------DQECQKYQV-----VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAA 1375
                  ++E Q  ++     +    C     +S S    C  L D  GPF  C   V   
Sbjct: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPE 2567

Query: 1376 SFFDSCMLDMCGFQG---LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKY 1432
             F + C+LD+C  Q     + L C  +S         GH V      H   +     S  
Sbjct: 2568 PFQEHCVLDLCSAQDPREQEELRCQVLS---------GHGVSS--RYHISELYDTLPS-- 2614

Query: 1433 SLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVG 1492
             LC    P        G             +P   L      P + CGC    G Y+++G
Sbjct: 2615 ILCQPGRPRGLRGPLRGRLRQ---------HPRLCLQWHPEPPLADCGCTSN-GIYYQLG 2664

Query: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGC 1534
              +    C + C C S+  + C+P+ CRA E C   +   GC
Sbjct: 2665 SSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGC 2706



 Score =  181 bits (460), Expect = 7e-45
 Identities = 127/454 (27%), Positives = 195/454 (42%), Gaps = 48/454 (10%)

Query: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCK 2270
            CP  + Y +C  +C  SC      C        C EGC+C PG++ S++ C+  S C C 
Sbjct: 1044 CPPNARYESC--ACPASCKSPRPSCG-----PLCREGCVCNPGFLFSDNHCIQASSCNCF 1096

Query: 2271 DAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
              +    P G  W S  CTE C C  G  ++C   +C + + CQL +     +  +  + 
Sbjct: 1097 YNNDYYEP-GAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTAT 1155

Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-VEGRNKMDPPRSSIFL 2388
             C VYGDP Y+TFDG  +   G+ TY+L +         +P   V  +N+         L
Sbjct: 1156 -CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG---NSTDPFFRVTAKNEEQGQEGVSCL 1211

Query: 2389 QEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGG 2448
             +V  T+    V L  G   +V  Q++ +P  P++ + +   G+ + L T+F L V + G
Sbjct: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271

Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
             +   +++ S Y G + GLCGNYD N  ND +   G+   +    GNSW+   ++     
Sbjct: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDE----- 1326

Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPE 2567
                  ++E Q  ++     +    C     +S S    C  L D  GPF  C   V   
Sbjct: 1327 ------DQECQKYQV-----VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAA 1375

Query: 2568 PFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQN--- 2624
             F + C+LD+C  Q     + L C  +S     CQ+AG A+  WR+   C   C  N   
Sbjct: 1376 SFFDSCMLDMCGFQG---LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKY 1432

Query: 2625 -----PCQN------DGQCREQGATFTCECEVGY 2647
                 PC +       G          CEC  G+
Sbjct: 1433 SLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGF 1466



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 18/59 (30%), Positives = 28/59 (47%)

Query: 1091 SSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHP 1149
            + C C  N  YY+ G+ + + +C++ C C     + C+   C    VC L N   GC P
Sbjct: 2650 ADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFP 2708


>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
          Length = 5405

 Score =  866 bits (2238), Expect = 0.0
 Identities = 554/1699 (32%), Positives = 779/1699 (45%), Gaps = 151/1699 (8%)

Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
            CP N+ YE C   CPASC SP P   P      C EGC C+ GF+ S + C+  ++ C C
Sbjct: 1950 CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2009

Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
            + N  Y+E G+E W    C++ CRC PG   + C  + CG   VC L  +GQ+GC P + 
Sbjct: 2010 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 2068

Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
            TA C  +GDPHYVT DG  F F G C Y+L+ PC         F VT  NE +G + VS 
Sbjct: 2069 TAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 2128

Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
               V + +   ++TL     R+  V G  VTLP      +    SG  V + T  GL + 
Sbjct: 2129 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLA 2188

Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
            +DGD  + + V + Y+G LCGLCGNY+ +  +D   + G PAG        WQ      Q
Sbjct: 2189 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 2238

Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
             C +      PS C    Q S  GP  CG +  T GP   C   V  A +F  C+LD C 
Sbjct: 2239 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 2298

Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
             QG    LC  ++T    CQ AG  ++ WR P FCP  CP +S Y LC   CP +C S  
Sbjct: 2299 VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLS 2358

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
            +   C   C E C C+ GFVLSG  C+P  QCGCLH    Y+ +G+ +Y  PGC  LC C
Sbjct: 2359 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSLCRC 2417

Query: 1507 ESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTY 1566
                 + C+P  C   E C    G  GC A G+ TC ASGDPHY TFDG    FMGTC Y
Sbjct: 2418 REGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVY 2477

Query: 1567 VLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
            VL + C +R     F V   N   G G + V+ +  V V  F L +   R  KV +NG  
Sbjct: 2478 VLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVNGVD 2536

Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
            + LPV LA G++      + V++ T+FGL+V YD  + V VTVP +Y   +CGLCGNYN 
Sbjct: 2537 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 2596

Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWK--LPES----------SEPGCFLVGGKPSSCQENS 1733
            +  DD  +P+   AG++ + G +W+  +P+S             GC      P   ++  
Sbjct: 2597 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKY 2656

Query: 1734 MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC 1793
              + +   C +L +P GP S CH++V PQ     C+   C   G+ + LC ++ AY S C
Sbjct: 2657 QKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713

Query: 1794 -AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQK 1852
             A  GQ   WRN TFCPM CP  S Y  C+  C   CS+++ P  CP    CAE C+C  
Sbjct: 2714 QAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQCDS 2771

Query: 1853 GHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQ 1912
            G + +G +CVP+ QCGC      Y P  E+    + C + CTC V   + C + +CKP Q
Sbjct: 2772 GFLYNGQACVPIQQCGCYHNGAYYEP--EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 2829

Query: 1913 ICWALDGLLRC------------------RASGVGV--------CQLPGESHYVSFDGSN 1946
            +C    G+L C                     G GV        C L G+ HY SFDG  
Sbjct: 2830 VCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 2889

Query: 1947 HSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
                  C  VL     P ++   L  F ++ K++   G      +  V +      +++ 
Sbjct: 2890 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NRGNPAVSYVRVVTVAALGTNISIH 2948

Query: 2004 KGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
            K    +V +N     LP       +SV   +  +++    G+QV +D N  +++ +P++Y
Sbjct: 2949 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 3008

Query: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDP----SCQSLLVDEQQI 2117
            +G VCG+CGN +    ++ + P+  +A S   +  SW+    DP     C+       + 
Sbjct: 3009 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPED 3068

Query: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
              EQ E P G C             A      +  C + +    F   C   +C  GG  
Sbjct: 3069 RLEQYEGP-GFCGPL----------APGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 3117

Query: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
              LC+AL ++ A CQ+ G+    WR    C + CP  S Y  C P C  SC         
Sbjct: 3118 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 3177

Query: 2238 AKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC- 2294
            A     C EGC C  G+VLS D+CVP  + CGC  A+G     G   W    C++ C C 
Sbjct: 3178 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 3236

Query: 2295 -TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
              GG++ C    C  G  C L     +  C    + +C  +GDP Y+T DG  +  QG  
Sbjct: 3237 PGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 3295

Query: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQA--GLELVVN 2411
             Y+L       P G E   V   N+    ++  + + V   +Y + + L A    +L V+
Sbjct: 3296 EYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355

Query: 2412 NQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNY 2471
               + +P++ +  L   L G  + + T   L ++F G     + +P+ Y G + GLCGNY
Sbjct: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415

Query: 2472 DKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQV 2531
            +++  +D+    G            W+V                 +G G  +        
Sbjct: 3416 NQDPADDLKAVGGKPA--------GWQV--------------GGAQGCGECVSKPC---P 3450

Query: 2532 SECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELR 2590
            S C+PEQ  S     AC V++   GP A CH  V P  + + C+LD C  Q         
Sbjct: 3451 SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG---HPGGL 3507

Query: 2591 CQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNP----CQND--GQCREQGATFTCE-- 2642
            C  ++ Y   CQ AGA L  WR    C   C  +     C +   G C    A   CE  
Sbjct: 3508 CPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESA 3567

Query: 2643 ------CEVGY--GGGLCM 2653
                  C+ G+   G  C+
Sbjct: 3568 CREGCVCDAGFVLSGDTCV 3586



 Score =  862 bits (2227), Expect = 0.0
 Identities = 543/1651 (32%), Positives = 764/1651 (46%), Gaps = 135/1651 (8%)

Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
            CP N+ YE C   CPASC SP P   P      C EGC C+ GF+ S + C+  ++ C C
Sbjct: 3151 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 3210

Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
            + N  Y+E G+E W    C++ CRC PG   + C  + CG   VC L  +GQ+GC P + 
Sbjct: 3211 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 3269

Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
            TA C  +GDPHYVT DG  F F G C Y+L+ PC         F VT  NE +G + VS 
Sbjct: 3270 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 3329

Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
               V + +   ++TL     R+  V G  VTLP      +    SG  V + T  GL + 
Sbjct: 3330 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLA 3389

Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
            +DGD  + + V + Y+G LCGLCGNY+ +  +D   + G PAG        WQ      Q
Sbjct: 3390 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 3439

Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
             C +      PS C    Q S  GP  CG +  T GP   C   V  A +F  C+LD C 
Sbjct: 3440 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 3499

Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
             QG    LC  ++T    CQ AG  ++ WR P FCP  CP +S Y LC   CP +C S  
Sbjct: 3500 VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLS 3559

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
            +   C   C E C C+ GFVLSG  C+P  QCGCLH    Y+ +G+ +Y  PGC  LC C
Sbjct: 3560 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSLCRC 3618

Query: 1507 ESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTY 1566
                 + C+P  C   E C    G  GC A G+ TC ASGDPHY TFDG    FMGTC Y
Sbjct: 3619 REGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVY 3678

Query: 1567 VLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
            VL + C +R     F V   N   G G + V+ +  V V  F L +   R  KV +NG  
Sbjct: 3679 VLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVNGVD 3737

Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
            + LPV LA G++      + V++ T+FGL+V YD  + V VTVP +Y   +CGLCGNYN 
Sbjct: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797

Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWK--LPES----------SEPGCFLVGGKPSSCQENS 1733
            +  DD  +P+   AG++ + G +W+  +P+S             GC      P   ++  
Sbjct: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKY 3857

Query: 1734 MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC 1793
              + +   C +L +P GP S CH++V PQ     C+   C   G+ + LC ++ AY S C
Sbjct: 3858 QKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 3914

Query: 1794 -AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQK 1852
             A  G    WRN TFCPM CP  S Y  C+  C   CS+++ P  CP    CAE C+C  
Sbjct: 3915 QAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQCDS 3972

Query: 1853 GHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQ 1912
            G + +G +CVP+ QCGC      Y P  E+    + C + CTC V   + C + +CKP Q
Sbjct: 3973 GFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 4030

Query: 1913 ICWALDGLLRC------------------RASGVGV--------CQLPGESHYVSFDGSN 1946
            +C    G+L C                     G GV        C L G+ HY SFDG  
Sbjct: 4031 VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 4090

Query: 1947 HSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
                  C  VL     P ++   L  F ++ K++   G      +  V +      +++ 
Sbjct: 4091 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NRGNPAVSYVRVVTVAALGTNISIH 4149

Query: 2004 KGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
            K    +V +N     LP       +SV   +  +++    G+QV +D N  +++ +P++Y
Sbjct: 4150 KDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 4209

Query: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDP----SCQSLLVDEQQI 2117
            +G VCG+CGN +    ++ + P+  +A S   +  SW+    DP     C+       + 
Sbjct: 4210 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPED 4269

Query: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
              EQ E P G C             +    P +  C + +    F   C   +C  GG  
Sbjct: 4270 RLEQYEGP-GFC---------GPLSSGTGGP-FTTCHAHVPPESFFKGCVLDVCMGGGDR 4318

Query: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
              LC+AL ++ A CQ+ G+    WR    C + CP  S Y  C P C  SC         
Sbjct: 4319 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 4378

Query: 2238 AKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC- 2294
            A     C EGC C  G+VLS D+CVP  + CGC  A+G     G   W    C++ C C 
Sbjct: 4379 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 4437

Query: 2295 -TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
              GG++ C    C  G  C L     +  C    + +C  +GDP Y+T DG  +  QG  
Sbjct: 4438 PGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 4496

Query: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQA--GLELVVN 2411
             Y+L       P G E   V   N+    ++  + + V   +Y + + L A    +L V+
Sbjct: 4497 EYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556

Query: 2412 NQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNY 2471
               +A+P++ +  L   L G  + + T   L ++F G     + +P+ Y   + GLCGNY
Sbjct: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616

Query: 2472 DKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQV 2531
            +++  +D+    G            W+V                 +G G  +        
Sbjct: 4617 NQDPADDLKAVGGKPA--------GWQV--------------GGAQGCGECVSKPC---P 4651

Query: 2532 SECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELR 2590
            S C+PEQ  S     AC V++   GP A CH  V P  + + C+LD C  Q         
Sbjct: 4652 SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG---HPGGL 4708

Query: 2591 CQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            C  ++ Y   CQ AGA L  WR    C   C
Sbjct: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQC 4739



 Score =  851 bits (2198), Expect = 0.0
 Identities = 548/1698 (32%), Positives = 779/1698 (45%), Gaps = 138/1698 (8%)

Query: 1043 RCPPNARYESC--ACPASCKS--PRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
            +CP ++ YE C  +CP SC S      C   CREGCVC+ GF+ S + C+    C C ++
Sbjct: 2336 QCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 2395

Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
            + YY  G  ++  P C   CRC  G  V C+ S CG H  C+   G  GC    G+ TC 
Sbjct: 2396 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVA-VGSTTCQ 2454

Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYV 1216
              GDPHY TFDGR F FMG C Y+LAQ CG       F V  +N   G   VS    + V
Sbjct: 2455 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 2514

Query: 1217 TLPESTVTLLKGR-RTLVGGQQVTLPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQ 1274
             +   T+ L + + +  V G  + LP + + G    +  G  V ++T+FGLRV +D    
Sbjct: 2515 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 2574

Query: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334
            + VTV   Y   +CGLCGNY+G+  +D  K +GS AG+  E GNSW+ +   D  C    
Sbjct: 2575 VRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPP 2633

Query: 1335 V--------VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMC 1386
                     + S  C   L+       FCG L    GP  +C   V        C+ D+C
Sbjct: 2634 TCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 2693

Query: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
               G   +LC+++    + CQ AG  V+PWR   FCPM CP NS Y LCA  C   C + 
Sbjct: 2694 LGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSAL 2753

Query: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC 1506
             + + C D C E C+C+ GF+ +G  C+P  QCGC H  G+Y++  +      C++ C C
Sbjct: 2754 SAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHN-GAYYEPEQTVLIDNCRQQCTC 2812

Query: 1507 ESNNRIRCQPWRC--------------------------RAQEFCGQQDGIYGCHAQGAA 1540
                 + CQ   C                          R QE C +Q G   C     A
Sbjct: 2813 HVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 2872

Query: 1541 TCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVS 1597
            TC   GDPHY +FDG    F GTC YVL     P  S    + F V+  N+NRG    VS
Sbjct: 2873 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPA-VS 2931

Query: 1598 YIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
            Y++ V V     +IS+ +    KV +NG   ALPV +A GR+++   ++  LL  +FGLQ
Sbjct: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 2991

Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESS 1715
            V YD +  V+VT+PSSY G +CGLCGN + N  +D + P+  LA      G +W+ P   
Sbjct: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GW 3050

Query: 1716 EPGCF-LVGGKPSSCQENSMADAWNKNCAILINPQ--GPFSQCHQVVPPQSSFASCVHGQ 1772
            +P C+    G   +C E+ +           + P   GPF+ CH  VPP+S F  CV   
Sbjct: 3051 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110

Query: 1773 CGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS 1831
            C   GD   LC++L +Y + C  AG     WR +  C + CP  S Y  C  PCP +C S
Sbjct: 3111 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 3170

Query: 1832 ---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTEN 1887
               +  P  C    PC E C+C  G +LS   CVPL   CGC    G+YH  G  ++ + 
Sbjct: 3171 PAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADG 3227

Query: 1888 TCTRLCTCSVHN-NITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDGS 1945
            TC++ C C     ++ C  ++C   ++C  L  G   C+      CQ  G+ HYV+ DG 
Sbjct: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 3287

Query: 1946 NHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQK 2004
                   C  +L   CH P +    F ++  +E   G         V + IY+  +TL  
Sbjct: 3288 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLSA 3346

Query: 2005 G--HRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
                ++ ++   VTLP  +  +    +  + +  +V    G+ + FDG+  + + +P  Y
Sbjct: 3347 RWPRKLQVDGVFVTLPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAAY 3404

Query: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQIP 2118
             G +CG+CGN+N +  D+L     + A      ++       K     C           
Sbjct: 3405 AGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP--------- 3455

Query: 2119 AEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
             EQQE+  G      +        +A   P+ A C   +    +   C    C+  G   
Sbjct: 3456 -EQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHPG 3505

Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGA 2238
             LC A+  + A CQ+ G +   WR   FCP +CPA+S Y  C  SC  SC  L    EG 
Sbjct: 3506 GLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAP-EGC 3564

Query: 2239 KVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSS-GCTEKCVCT-G 2296
            +  SAC EGC+C  G+VLS D CVP  QCGC        PLG+++    GC   C C  G
Sbjct: 3565 E--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DDRYYPLGQTFYPGPGCDSLCRCREG 3621

Query: 2297 GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYV 2356
            G + C    C  G H        +  CV+  S  C   GDP Y TFDG  +   G   YV
Sbjct: 3622 GEVSCEPSSC--GPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYV 3679

Query: 2357 LIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT-VYGYKVQL-QAGLELVVNNQK 2414
            L +T    P G+    V   N +      + +  VIT  V  + ++L Q   ++ VN   
Sbjct: 3680 LAQTCGTRP-GLHRFAVLQEN-VAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 3737

Query: 2415 MAVPY-RPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDK 2473
            M +P    N  +R +  G  + + TDF L V++       +++P  Y  L+ GLCGNY+ 
Sbjct: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797

Query: 2474 NRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSE 2533
            + K+D   P+G+   N N FGNSWE    D+    P   P    G          +   +
Sbjct: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGC---------IPSDK 3848

Query: 2534 CSPE-QLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQ 2592
            C PE +      + C +L+ P GP ++CH+ V P+   + C+ DLC          + C 
Sbjct: 3849 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG---NLSILCS 3905

Query: 2593 VLSGYAILCQEAGAALAGWRDRTLCESPCLQNP----CQNDG-----------QCREQGA 2637
             +  Y   CQ AG  +  WR+ T C   C QN     C +             QC + G 
Sbjct: 3906 NIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD-GC 3964

Query: 2638 TFTCECEVG--YGGGLCM 2653
               C+C+ G  Y G  C+
Sbjct: 3965 AEGCQCDSGFLYNGQACV 3982



 Score =  846 bits (2185), Expect = 0.0
 Identities = 535/1646 (32%), Positives = 768/1646 (46%), Gaps = 128/1646 (7%)

Query: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
            +CP ++ YE C  +CP SC   S    C   CREGCVC+ GF+ S + C+    C C ++
Sbjct: 3537 QCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 3596

Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
            + YY  G  ++  P C   CRC  G  V C+ S CG H  C+   G  GC    G+ TC 
Sbjct: 3597 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGC-VAVGSTTCQ 3655

Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYV 1216
              GDPHY TFDG  F FMG C Y+LAQ CG       F V  +N   G   VS    + V
Sbjct: 3656 ASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 3715

Query: 1217 TLPESTVTLLKGR-RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQ 1274
             +   T+ L + + +  V G  + LP + + G +     G  V ++T+FGLRV +D    
Sbjct: 3716 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 3775

Query: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC---- 1330
            + VTV   Y   +CGLCGNY+G+  +D  K +GS AG+  E GNSW+ +   D  C    
Sbjct: 3776 VRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPP 3834

Query: 1331 ----QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMC 1386
                     + S  C   L+       FCG L    GP  +C   V        C+ D+C
Sbjct: 3835 TCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 3894

Query: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
               G   +LC+++    + CQ AG  V+PWR   FCPM CP NS Y LCA  C   C + 
Sbjct: 3895 LGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSAL 3954

Query: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC 1506
             + + C D C E C+C+ GF+ +G  C+P  QCGC H  G Y++  +      C++ C C
Sbjct: 3955 SAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTC 4013

Query: 1507 ESNNRIRCQPW--------------------------RCRAQEFCGQQDGIYGCHAQGAA 1540
                 + CQ                             CR QE C +Q G   C     A
Sbjct: 4014 HVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 4073

Query: 1541 TCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVS 1597
            TC   GDPHY +FDG    F GTC YVL     P  S    + F V+  N+NRG    VS
Sbjct: 4074 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGN-PAVS 4132

Query: 1598 YIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
            Y++ V V     +IS+ +    KV +NG   ALPV +A GR+++   ++  LL  +FGLQ
Sbjct: 4133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 4192

Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESS 1715
            V YD +  V+VT+PSSY G +CGLCGN + N  +D + P+  LA      G +W+ P   
Sbjct: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GW 4251

Query: 1716 EPGCF-LVGGKPSSCQENSMADAWNKN-CAILIN-PQGPFSQCHQVVPPQSSFASCVHGQ 1772
            +P C+    G   +C E+ +        C  L +   GPF+ CH  VPP+S F  CV   
Sbjct: 4252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311

Query: 1773 CGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS 1831
            C   GD   LC++L +Y + C  AG     WR +  C + CP  S Y  C  PCP +C S
Sbjct: 4312 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371

Query: 1832 ---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTEN 1887
               +  P  C    PC E C+C  G +LS   CVPL   CGC    G+YH  G  ++ + 
Sbjct: 4372 PAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADG 4428

Query: 1888 TCTRLCTCSV-HNNITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDGS 1945
            TC++ C C     ++ C  ++C   ++C  L  G   C+      CQ  G+ HYV+ DG 
Sbjct: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 4488

Query: 1946 NHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQK 2004
                   C  +L   CH P +    F ++  +E   G         V + IY+  +TL  
Sbjct: 4489 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLSA 4547

Query: 2005 --GHRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
                ++ ++   V LP  +  +    +  + +  +V    G+ + FDG+  + + +P  Y
Sbjct: 4548 RWPRKLQVDGVFVALPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAAY 4605

Query: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQIP 2118
               +CG+CGN+N +  D+L     + A      ++       K     C           
Sbjct: 4606 AASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPC----------T 4655

Query: 2119 AEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
             EQQE+  G      +        +A   P+ A C   +    +   C    C+  G   
Sbjct: 4656 PEQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHPG 4706

Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGA 2238
             LC A+  + A CQ+ G +   WR   FCPL+CPA+S Y  C  SC  SC  L    EG 
Sbjct: 4707 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGC 4765

Query: 2239 KVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGK-SWVSSGCTEKCVC-TG 2296
            +  SAC EGC+C  G+VLS D CVP  QCGC    G   PLG+  +    C  +C C  G
Sbjct: 4766 E--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DGRYYPLGEVFYPGPECERRCECGPG 4822

Query: 2297 GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYV 2356
            G + C +     G H +   ++    C +    +C   G   Y+T DG  Y L G  +YV
Sbjct: 4823 GHVTCQE-GAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 4881

Query: 2357 LIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMA 2416
            L +     P   +  +V  +N          LQ ++ TV G  V L  G ++ V+ + +A
Sbjct: 4882 LAQVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVAGQVVSLAQGQQVTVDGEAVA 4935

Query: 2417 VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRK 2476
            +P      +RVT  G+ + L T   L + F G  + ++S+PS + G + GLCGN++ N  
Sbjct: 4936 LPVAVG-RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 4994

Query: 2477 NDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSP 2536
            +D +LP+G+   ++ TFG +W               P   +G G   G + G  V  C  
Sbjct: 4995 DDFVLPNGSAASSVETFGAAWRA-------------PGSSKGCGEGCGPQ-GCPV--CLA 5038

Query: 2537 EQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLS 2595
            E+ A   S +AC  L +PQGPFA C   ++P  +   CV DLC+    +  +   C+ L+
Sbjct: 5039 EETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLA 5095

Query: 2596 GYAILCQEAGAALAGWRDRTLCESPC 2621
             Y   CQ AG A+  WR  + C   C
Sbjct: 5096 AYTAACQAAGVAVKPWRTDSFCPLHC 5121



 Score =  835 bits (2157), Expect = 0.0
 Identities = 544/1722 (31%), Positives = 780/1722 (45%), Gaps = 139/1722 (8%)

Query: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
            +S +A +     + +G   +  +    CP N+RYE C  ACP SC    +P    G  C 
Sbjct: 718  LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 777

Query: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
            EGCVC PGF+ S   C+ ASSC C +      PG E W    C   C C   + +V C+ 
Sbjct: 778  EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837

Query: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
             Q C     C ++NG  GC+P     TC   GDPHYV+FDGR F FMG CTY+L   CG 
Sbjct: 838  KQSCPAGERCSVQNGLLGCYP-DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 896

Query: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLK--GRRTLVGGQQVTLPAIPS 1245
            N+  P FRV  +NE +G + VS    V V      V + +    + LV      LP   +
Sbjct: 897  NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 956

Query: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
             G V +   GR   ++T+FGL V +D + ++   V S+Y+  LCGLCGN++G+  +D   
Sbjct: 957  DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1016

Query: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
              G  A +    GNSWQ  ++    C   +  + P  DS +   +     CG L D  GP
Sbjct: 1017 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074

Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
            F  C   +        C+ D C   G    LC  ++T    CQ AG  V PWR    CP+
Sbjct: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134

Query: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
            +CPP+S Y  C+  CP +C        C   C E C C+ GF LSG  C+P + CGC+H 
Sbjct: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVH- 1193

Query: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
             G+Y   G+ +Y  PGC  LC C+    + C+   C   E C    G  GC A G++TC 
Sbjct: 1194 QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1253

Query: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
            ASGDPHY TFDG    FMGTC YVL + C +R     F V   N   G G + V+ +  V
Sbjct: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313

Query: 1603 HVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSH 1662
             V  F L +   R  KV +NG  + LPV LA G++      + V++ T+FGL+V YD  +
Sbjct: 1314 QVANFTLRLE-QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVY 1372

Query: 1663 LVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWK--LPES------ 1714
             V VTVP +Y  Q+CGLCGNYN +  DD  +P+   AG++ + G +W+  +P+S      
Sbjct: 1373 YVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT 1432

Query: 1715 -SEPG---CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVH 1770
               PG   C      P   ++    + +   C +L +P GP S CH++V PQ     C+ 
Sbjct: 1433 PCPPGSEDCIPSHKCPPELEKKYQKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIF 1489

Query: 1771 GQCGTKGDTTALCRSLQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
              C   G+ + LC ++ AY S C A  G    WR  TFCPM CPP S Y  C+  C   C
Sbjct: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549

Query: 1830 SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTC 1889
            S+++ P  C     CAE C+C  G + +G +CVP+ QCGC      Y P  E+    + C
Sbjct: 1550 SALSAPPQCQDG--CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNC 1605

Query: 1890 TRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC------------------RASGVGV- 1930
             + CTC     + C + +CKP Q+C    G+L C                     G GV 
Sbjct: 1606 RQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665

Query: 1931 -------CQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEE 1980
                   C L G+ HY SFDG        C  VL     P ++   L  F ++ K++   
Sbjct: 1666 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NR 1724

Query: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
            G      +  V +      +++ K    +V +N     LP       +SV   +  +++ 
Sbjct: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV 1784

Query: 2039 IKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSW 2098
               G+QV +D N  +++ +P++Y+G VCG+CGN +    ++ + P+  +A S   +  SW
Sbjct: 1785 ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 1844

Query: 2099 KDKDIDP----SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCA 2154
            +    DP     C+       +   EQ E P G C             A      +  C 
Sbjct: 1845 RAPGWDPLCWDECRGSCPTCPEDRLEQYEGP-GFCGPL----------APGTGGPFTTCH 1893

Query: 2155 SRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAY 2214
            + +    F   C   +C  GG    LC+AL ++ A CQ+ G+    WR    C + CP  
Sbjct: 1894 AHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPEN 1953

Query: 2215 SSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAH 2273
            S Y  C   C  SC         A     C EGC C  G+VLS D+CVP  + CGC  A+
Sbjct: 1954 SHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-AN 2012

Query: 2274 GGSIPLGKS-WVSSGCTEKCVC--TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQ 2330
            G     G   W    C++ C C   GG++ C    C  G  C L     +  C    + +
Sbjct: 2013 GTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAE 2071

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
            C  +GDP Y+T DG  +  QG   Y+L       P G E   V   N+    ++  + + 
Sbjct: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2131

Query: 2391 VITTVYGYKVQLQA--GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGG 2448
            V   +Y + + L A    +L V+   + +P++ +  L   L G  + + T   L ++F G
Sbjct: 2132 VTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191

Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
                 + +P+ Y G + GLCGNY+++  +D+    G            W+V         
Sbjct: 2192 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQV--------- 2234

Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPE 2567
                    +G G  +        S C+PEQ  S     AC V++   GP A CH  V P 
Sbjct: 2235 -----GGAQGCGECVSKPC---PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 2286

Query: 2568 PFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNP-- 2625
             + + C+LD C  Q         C  ++ Y   CQ AGA L  WR    C   C  +   
Sbjct: 2287 QYFQGCLLDACQVQG---HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHY 2343

Query: 2626 --CQND--GQCREQGATFTCE--------CEVGY--GGGLCM 2653
              C +   G C    A   CE        C+ G+   G  C+
Sbjct: 2344 ELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCV 2385



 Score =  834 bits (2154), Expect = 0.0
 Identities = 536/1669 (32%), Positives = 759/1669 (45%), Gaps = 134/1669 (8%)

Query: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
            CP N+ YE CA  C   C   S    C   C EGC C+ GFL++   C+    C C++N 
Sbjct: 2733 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 2792

Query: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
             YYEP       NC + C C  G  V CQ   C    VCQ   G   C    P  G    
Sbjct: 2793 AYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCR 2852

Query: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
                               ATC ++GDPHY +FDGR F F G C Y+LA   C G ST  
Sbjct: 2853 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 2912

Query: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG- 1247
               F VT KN+ +G   VS +  V V    + +++ K    +  V G    LP   + G 
Sbjct: 2913 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 2972

Query: 1248 --VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
              V  GAS     L  +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +  
Sbjct: 2973 ISVTQGASKAL--LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030

Query: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
            +G+ A      G SW+     D  C      + P+C         GPGFCG L   T GP
Sbjct: 3031 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGP 3089

Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
            F TC  HV   SFF  C+LD+C   G + +LC  +++    CQ AG  ++ WR    C +
Sbjct: 3090 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 3149

Query: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
             CP NS Y +C  PCP +C S     +   C   CVE C+C+ GFVLS   C+P +  CG
Sbjct: 3150 TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 3209

Query: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
            C    G+Y + G  ++  G C + C C      + C P  C   E CG    G +GC   
Sbjct: 3210 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 3268

Query: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
              A C A GDPHY+T DG    F GTC Y+L+ PC      +  F V+  NE+RG    V
Sbjct: 3269 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 3327

Query: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
            SY ++V + +++ S++L      K+ ++G  V LP  L    +   LS   V++ T  GL
Sbjct: 3328 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTTTSGL 3386

Query: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
             + +DG   V + VP++Y G LCGLCGNYN +  DD      K AG   Q+G A    E 
Sbjct: 3387 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 3444

Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
                C      PS C           + C ++    GP + CH +VPP   F  C+   C
Sbjct: 3445 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 3498

Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
              +G    LC ++  Y + C  AG Q   WR   FCP +CP  S Y  C   CP +C S+
Sbjct: 3499 QVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSL 3558

Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
            + P  C  A  C E C C  G +LSG +CVP+GQCGC      Y+P+G+ +Y    C  L
Sbjct: 3559 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSL 3615

Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
            C C     ++C  S+C P++ C    G L C A G   CQ  G+ HY +FDG        
Sbjct: 3616 CRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGT 3675

Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
            C  VL + C     L  F +  ++     G     R+  V +  +  ++  Q+  +V +N
Sbjct: 3676 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 3734

Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
               + LP +     +         ++    G++V +D  + + + +P  YY  +CG+CGN
Sbjct: 3735 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 3794

Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
            +N + +D+   P+   A + +EF NSW++   D  C   L      P      PS  C  
Sbjct: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPPTCPPGSAGCIPSDKC-P 3850

Query: 2132 ADLRRAREKCE--AALRAPVW--AQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
             +L +  +K E    L +P    + C   +D    L DC   LC  GG    LC  + A+
Sbjct: 3851 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 3910

Query: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
             + CQ+ G     WRN +FCP+ECP  S Y  C  +CS  C  L    +    P  CAEG
Sbjct: 3911 VSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ---CPDGCAEG 3967

Query: 2248 CICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRC 2306
            C C  G++ +   CVP  QCGC   +G      ++ +   C ++C C  G  + C +  C
Sbjct: 3968 CQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 4026

Query: 2307 PSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPRYLTF 2342
              G  CQ        +T D                     C+ +    C ++GDP Y +F
Sbjct: 4027 KPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSF 4086

Query: 2343 DGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
            DG  +  QG   YVL  T    V  +G+ P  V  +N+     +  +++ V     G  +
Sbjct: 4087 DGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNI 4146

Query: 2401 QLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
             +      ++ VN    A+P    +  + V     +  LV DF L VS+       ++LP
Sbjct: 4147 SIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLP 4206

Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
            S Y G V GLCGN D+N  ND + P+G L  ++  +G SW     D L          +E
Sbjct: 4207 SSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL--------CWDE 4258

Query: 2518 GQGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQG-PFAACHQTVAPEPFQEHCVL 2575
             +G+            C  ++L        C  L+   G PF  CH  V PE F + CVL
Sbjct: 4259 CRGS---------CPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVL 4309

Query: 2576 DLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQN 2624
            D+C     R+   + C+ L+ Y   CQ AG  +  WR +  CE  C +N
Sbjct: 4310 DVCMGGGDRD---ILCKALASYVAACQAAGVVIEDWRAQVGCEITCPEN 4355



 Score =  813 bits (2100), Expect = 0.0
 Identities = 512/1596 (32%), Positives = 742/1596 (46%), Gaps = 121/1596 (7%)

Query: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
            C+  QC     CQ+  G+ GC   + TA C   GDPHY TFDGR +  MG C+Y + + C
Sbjct: 444  CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502

Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
              + T P F V AKNE +G   VS +  V V     +V+L +G     LV  Q+  LP  
Sbjct: 503  SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562

Query: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
             S+G + +  SG    ++  FGL V +D D QL +++ + +  ++CGLCGNY+G+  +D 
Sbjct: 563  LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622

Query: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
            L  DG+ A D  E  +SW+ D D D  C+     N P+C         G   CG L    
Sbjct: 623  LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681

Query: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
            GPF  C   +    F + C+ D+C   G +  LC  +S     C + G +V  WR P  C
Sbjct: 682  GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741

Query: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
            P++CP NS+Y LC   CP +C+   +   CS R CVE C C PGFV SG  C+P S CGC
Sbjct: 742  PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801

Query: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
                       E W    C+  C C  + +++ C+  + C A E C  Q+G+ GC+    
Sbjct: 802  TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861

Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
             TC  SGDPHY++FDG    FMGTCTY+L   C   +    F V   NE+RG    VSY 
Sbjct: 862  GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 920

Query: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
            +AV V    + +++ R    +V+++     LP   A G+V +       ++ T+FGL V 
Sbjct: 921  RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 980

Query: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
            YD +  V   VPSSY   LCGLCGN+N +  DD        A +++  G +W+  E + P
Sbjct: 981  YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1038

Query: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
            GC     +P  C +     A    +KN C IL +P+GPF +CH  + PQ +   CV+ +C
Sbjct: 1039 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096

Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
               G +  LC +L  YA+ C  AG     WR+   CP+ CPP S Y  CS  CP +C  +
Sbjct: 1097 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1156

Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
              P  C     C E C C +G  LSG SC+PL  CGC    G+YHP G+ +Y    C  L
Sbjct: 1157 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1213

Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
            C C     ++C  S+C P++ C    G L C A G   CQ  G+ HY +FDG        
Sbjct: 1214 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1273

Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
            C  VL + C     L  F +  ++     G     R+  V +  +  ++  Q+  +V +N
Sbjct: 1274 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 1332

Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
               + LP +     +         ++    G++V +D  + + + +P  YY ++CG+CGN
Sbjct: 1333 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGN 1392

Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
            +N + +D+   P+   A + +EF NSW++   D  C   L      P  +   PS  C  
Sbjct: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC-P 1448

Query: 2132 ADLRRAREKCE--AALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
             +L +  +K E    L +P    + C   +D    L DC   LC  GG    LC  + A+
Sbjct: 1449 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 1508

Query: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSACA 2245
             + CQ+ G     WR  +FCP+ECP  S Y  C  +CS  C  L    +C+       CA
Sbjct: 1509 VSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQ-----DGCA 1563

Query: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDF 2304
            EGC C  G++ +   CVP  QCGC   +G      ++ +   C ++C C  G  + C + 
Sbjct: 1564 EGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH 1622

Query: 2305 RCPSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPRYL 2340
             C  G  CQ        +T D                     C+ +    C ++GDP Y 
Sbjct: 1623 SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYH 1682

Query: 2341 TFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGY 2398
            +FDG  +  QG   YVL  T    V  +G+ P  V  +N+     +  +++ V     G 
Sbjct: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGT 1742

Query: 2399 KVQLQAGL--ELVVNNQKMAVPYR-PNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVIS 2455
             + +      ++ VN    A+P    +  + VT    +  LV DF L VS+       ++
Sbjct: 1743 NISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVT 1802

Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
            LPS Y G V GLCGN D+N  ND + P+G L  ++  +G SW     D L          
Sbjct: 1803 LPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL--------CW 1854

Query: 2516 EEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLA-DPQGPFAACHQTVAPEPFQEHC 2573
            +E +G+            C  ++L        C  LA    GPF  CH  V PE F + C
Sbjct: 1855 DECRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGC 1905

Query: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCE-------------SP 2620
            VLD+C     R   ++ C+ L+ Y   CQ AG  +  WR +  CE             SP
Sbjct: 1906 VLDVCMGGGDR---DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSP 1962

Query: 2621 C---------LQNPCQNDGQCREQGATFTCECEVGY 2647
            C         L  P   +G C E      C+C+ G+
Sbjct: 1963 CPASCPSPAPLTTPAVCEGPCVE-----GCQCDAGF 1993



 Score =  745 bits (1923), Expect = 0.0
 Identities = 482/1502 (32%), Positives = 696/1502 (46%), Gaps = 120/1502 (7%)

Query: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
            CP N+ YE CA  C   C   S    C   C EGC C+ GFL++   C+    C C++N 
Sbjct: 3934 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 3993

Query: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
             YYEP       NC + C C  G  V CQ   C    VCQ   G   C    P  G    
Sbjct: 3994 VYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 4053

Query: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
                               ATC ++GDPHY +FDGR F F G C Y+LA   C G ST  
Sbjct: 4054 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 4113

Query: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKGV 1248
               F VT KN+ +G   VS +  V V    + +++ K    +  V G    LP   + G 
Sbjct: 4114 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 4173

Query: 1249 FLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG 1307
               A G    L   +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +  +G
Sbjct: 4174 ISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233

Query: 1308 SPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGPFE 1366
            + A      G SW+     D  C      + P+C         GPGFCG L   T GPF 
Sbjct: 4234 TLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFT 4292

Query: 1367 TCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
            TC  HV   SFF  C+LD+C   G + +LC  +++    CQ AG  ++ WR    C + C
Sbjct: 4293 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 4352

Query: 1427 PPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CGCL 1482
            P NS Y +C  PCP +C S     +   C   CVE C+C+ GFVLS   C+P +  CGC 
Sbjct: 4353 PENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW 4412

Query: 1483 HPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQGA 1539
               G+Y + G  ++  G C + C C      + C P  C   E CG    G +GC     
Sbjct: 4413 -ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST 4471

Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEVSY 1598
            A C A GDPHY+T DG    F GTC Y+L+ PC      +  F V+  NE+RG    VSY
Sbjct: 4472 AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSY 4530

Query: 1599 IKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
             ++V + +++ S++L      K+ ++G  VALP  L    +   LS   V++ T  GL +
Sbjct: 4531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSL 4589

Query: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSE 1716
             +DG   V + VP++Y   LCGLCGNYN +  DD      K AG   Q+G A    E   
Sbjct: 4590 AFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGECVS 4647

Query: 1717 PGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
              C      PS C           + C ++    GP + CH +VPP   F  C+   C  
Sbjct: 4648 KPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQV 4701

Query: 1776 KGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINN 1834
            +G    LC ++  Y + C  AG Q   WR   FCP++CP  S Y  C   CP +C S++ 
Sbjct: 4702 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 4761

Query: 1835 PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCT 1894
            P  C  A  C E C C  G +LSG +CVP+GQCGC    G Y+P+GE +Y    C R C 
Sbjct: 4762 PEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCE 4818

Query: 1895 CSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDAC 1953
            C    ++TC + + C P++ C   DG+  C A+G G C   G  HY++ DG  + +  +C
Sbjct: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 4878

Query: 1954 TLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSK 2013
            + VL +VCHP      F I    EK   G     L  + + +    V+L +G +V ++ +
Sbjct: 4879 SYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQGQQVTVDGE 4932

Query: 2014 QVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFN 2073
             V LP    +  V V +     ++    G+++ FDG+  L + IP+ + G++CG+CGNFN
Sbjct: 4933 AVALPVA--VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN 4990

Query: 2074 DEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQIPAEQQENP 2125
                D+ ++P+   A+S   F  +W+       C          + + E+  P E  E  
Sbjct: 4991 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNE-- 5048

Query: 2126 SGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQ 2185
                    LR  +           +A C + +  + +   C   LC   G    LC++L 
Sbjct: 5049 ----ACGQLRNPQGP---------FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLA 5095

Query: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACA 2245
            A+ A CQ+ G+    WR  SFCPL CPA+S Y+ C  +C  SC  L G        + C 
Sbjct: 5096 AYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL---TGCTTRCF 5152

Query: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA-IQCGDF 2304
            EGC C   ++LS+  C+P   CGC   +G  +P+  S ++S C+E+C C+  + + C   
Sbjct: 5153 EGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAA 5211

Query: 2305 RCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIK 2359
             CP G  C++ ++  N       CV       + +   R  T     Y L  R    L  
Sbjct: 5212 GCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP-GLQN 5270

Query: 2360 TVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMA--- 2416
            T+       E  +  G+ +    +  IF Q+ + T+   K     GL + +  +K+A   
Sbjct: 5271 TIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVS 5329

Query: 2417 VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRK 2476
            V   P+  L V              + V  G      + + + + G + G CGN+D ++ 
Sbjct: 5330 VSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQT 5380

Query: 2477 ND 2478
            ND
Sbjct: 5381 ND 5382



 Score =  646 bits (1667), Expect = 0.0
 Identities = 392/1088 (36%), Positives = 549/1088 (50%), Gaps = 63/1088 (5%)

Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
            CP N+ YE C   CPASC SP P   P      C EGC C+ GF+ S + C+  ++ C C
Sbjct: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 4411

Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
            + N  Y+E G+E W    C++ CRC PG   + C  + CG   VC L  +GQ+GC P + 
Sbjct: 4412 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 4470

Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
            TA C  +GDPHYVT DG  F F G C Y+L+ PC         F VT  NE +G + VS 
Sbjct: 4471 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 4530

Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
               V + +   ++TL     R+  V G  V LP      +    SG  V + T  GL + 
Sbjct: 4531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 4590

Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
            +DGD  + + V + Y+  LCGLCGNY+ +  +D   + G PAG        WQ      Q
Sbjct: 4591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 4640

Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
             C +      PS C    Q S  GP  CG +  T GP   C   V  A +F  C+LD C 
Sbjct: 4641 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 4700

Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
             QG    LC  ++T    CQ AG  +  WR P FCP+ CP +S Y LC   CP +C S  
Sbjct: 4701 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 4760

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
            +   C   C E C C+ GFVLSG  C+P  QCGCLH  G Y+ +GE +Y  P C+  C C
Sbjct: 4761 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 4819

Query: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
                 + CQ    C   E C  +DG+  CHA G   C A+G  HY+T DG ++   G+C+
Sbjct: 4820 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 4879

Query: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
            YVL + C  +  D  F +    +N  G L+      + VTV    +SL +G +V ++G  
Sbjct: 4880 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 4933

Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
            VALPV  A GRV +      ++L T  GL++ +DG   + +++PS + G+LCGLCGN+N 
Sbjct: 4934 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 4991

Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
            N  DD + P+   A      GAAW+ P SS+ GC   G  P  C     E +     N+ 
Sbjct: 4992 NWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 5049

Query: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
            C  L NPQGPF+ C  V+ P   F  CV+  C  KGD   LCRSL AY + C  AG A  
Sbjct: 5050 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 5109

Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
             WR  +FCP+ CP  S YS C+  C  +C++++    C     C E CEC    +LS   
Sbjct: 5110 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 5167

Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
            C+P+  CGCT   G Y PV     T + C+  C+CS  + +TC  + C P ++C      
Sbjct: 5168 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 5225

Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
              C A+  G+C L   ++  +FDG+  +        L   C P +   +P++++ A+ + 
Sbjct: 5226 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 5283

Query: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
              G TEA  + +V+I   D  VTL     V +N  +V LPA  ++  VSV  +   S +V
Sbjct: 5284 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 5340

Query: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
              K GVQV    N  + + +   + GK+CG CGNF+ ++ ++     ++ A      +  
Sbjct: 5341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 5394

Query: 2098 WKDKDIDP 2105
            W+ +D  P
Sbjct: 5395 WRAQDFSP 5402



 Score =  376 bits (965), Expect = e-103
 Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)

Query: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
            +CP ++ YE C  +CP SC   S    C   CREGCVC+ GF+ S + C+    C C ++
Sbjct: 4738 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 4797

Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
              YY  G  ++  P C   C C PG  V CQ  + CG H  C+L++G   CH   G   C
Sbjct: 4798 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 4856

Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
            L  G  HY+T DGR +   G C+Y+LAQ C     D  F +  +    G      L ++ 
Sbjct: 4857 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 4911

Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
            VT+    V+L +G++  V G+ V LP    + V + A GR + LQT  GLR+ +DGD  L
Sbjct: 4912 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 4970

Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
             +++ S + G+LCGLCGN++GN  +D +  +GS A   E  G +W+         +    
Sbjct: 4971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 5030

Query: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
               P C +   +       CG+L +  GPF TC   +  + +F  C+ D+C  +G +  L
Sbjct: 5031 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 5090

Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
            C  ++  T  CQ AG AVKPWR   FCP+ CP +S YS+C + C  +C   SG +G  C+
Sbjct: 5091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 5148

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
             RC E CEC+  F+LS   CIP   CGC H  G Y  V        C E C C S++ + 
Sbjct: 5149 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 5207

Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
            CQ   C     C  +     C A     C  S   +  TFDGA         Y L+  C 
Sbjct: 5208 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 5266

Query: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
                +   Y VV+      G   +   +  VH+   D  ++L     V +NG RV LP  
Sbjct: 5267 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 5323

Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
                    R     +L+    G+QV    +  V V V + + G+LCG CGN++ +  +D
Sbjct: 5324 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 5382



 Score =  326 bits (836), Expect = 2e-88
 Identities = 220/739 (29%), Positives = 330/739 (44%), Gaps = 64/739 (8%)

Query: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
            +C    C   Q C  + G   C A    VC+  G+ HY +FDG  + +   C+  +V++C
Sbjct: 443  SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502

Query: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPA 2019
                 LP F + AK+E   G      +  V +  Y   V+L +G    VL+++++  LP 
Sbjct: 503  SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561

Query: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
                  + V  S   ++V +  G+ V +D +  L + +P  +  +VCG+CGN+N +  D+
Sbjct: 562  SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621

Query: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
             + P   +A    EF +SWK  D D  C+     +   PA    Q ++  G+     L +
Sbjct: 622  FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 679

Query: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
                    L  P +A C   +D  PFL  C   LC  GG   +LC+ L A+   C   G+
Sbjct: 680  --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 730

Query: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
                WR+ + CPL CPA S Y  C P+C  S       C GA  PS      C EGC+C 
Sbjct: 731  SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 783

Query: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
            PG+V S   CVP S CGC        P  + W    C  +C C G    + C D + CP+
Sbjct: 784  PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843

Query: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
            G  C +   N    C  D+   C   GDP Y++FDG  +   G  TY+L+ +      LP
Sbjct: 844  GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 901

Query: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
                 +LVE  ++     S  + + V     G KV ++     +++V++    +P++  +
Sbjct: 902  --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957

Query: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
              ++V   G+   + TDF L V++         +PS Y   + GLCGN++ +  +D+ L 
Sbjct: 958  GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017

Query: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
             G    N   FGNSW+ +T            A E G   +L      Q+           
Sbjct: 1018 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1060

Query: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQ 2602
            S   C +LADP+GPF  CH  + P+     CV D C    P +   L C  L+ YA  CQ
Sbjct: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1117

Query: 2603 EAGAALAGWRDRTLCESPC 2621
             AGA +  WR   LC   C
Sbjct: 1118 AAGATVHPWRSEELCPLSC 1136


>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
            sapiens]
          Length = 3003

 Score =  856 bits (2211), Expect = 0.0
 Identities = 539/1647 (32%), Positives = 772/1647 (46%), Gaps = 130/1647 (7%)

Query: 1044 CPPNARYESCA--CPASCKS-PRPS-CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
            CPP++ YE+C+  CP SC   P P  CG  C EGCVC+ GF  S   C+  +SC C +  
Sbjct: 1136 CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQG 1195

Query: 1100 DYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
             Y+ PG  ++  P C   C C  G  V C+ S CG H  CQ   G  GC    G++TC  
Sbjct: 1196 TYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVA-VGSSTCQA 1254

Query: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYVT 1217
             GDPHY TFDGR F FMG C Y+LAQ CG       F V  +N   G   VS    + V 
Sbjct: 1255 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQ 1314

Query: 1218 LPESTVTLLKGR-RTLVGGQQVTLPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQL 1275
            +   T+ L + + +  V G  + LP + + G    +  G  V ++T+FGLRV +D    +
Sbjct: 1315 VANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYV 1374

Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ---- 1331
             VTV   Y  ++CGLCGNY+G+  +D  K +GS AG+  E GNSW+ +   D  C     
Sbjct: 1375 RVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPTP 1433

Query: 1332 ----KYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
                    + S  C   L+       FCG L    GP  +C   V        C+ D+C 
Sbjct: 1434 CPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 1493

Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
              G   +LC+++    + CQ AG  V+PWR   FCPM CPPNS Y LCA  C   C +  
Sbjct: 1494 GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALS 1553

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCE 1507
            +   C D C E C+C+ GF+ +G  C+P  QCGC H  G Y++  +      C++ C C 
Sbjct: 1554 APPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHN-GVYYEPEQTVLIDNCRQQCTCH 1612

Query: 1508 SNNRIRCQPWRC--------------------------RAQEFCGQQDGIYGCHAQGAAT 1541
            +   + CQ   C                          R QE C +Q G   C     AT
Sbjct: 1613 AGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEAT 1672

Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVSY 1598
            C   GDPHY +FDG    F GTC YVL     P  S    + F V+  N+NRG    VSY
Sbjct: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPA-VSY 1731

Query: 1599 IKAVHVTVFDLSISLLRG----CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
            ++ V V     +IS+ +      +V +NG   ALPV +A GR+++   ++  LL  +FGL
Sbjct: 1732 VRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGL 1791

Query: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
            QV YD +  V+VT+PSSY G +CGLCGN + N  +D + P+  LA      G +W+ P  
Sbjct: 1792 QVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-G 1850

Query: 1715 SEPGCF-LVGGKPSSCQENSMADAWNKN-CAILINPQG-PFSQCHQVVPPQSSFASCVHG 1771
             +P C+    G   +C E+ +        C  L +  G PF+ CH  VPP+S F  CV  
Sbjct: 1851 WDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLD 1910

Query: 1772 QCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
             C   GD   LC++L +Y + C  AG     WR +  C + CP  S Y  C  PCP +C 
Sbjct: 1911 VCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCP 1970

Query: 1831 S---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTE 1886
            S   +  P  C    PC E C+C  G +LS   CVPL   CGC    G+YH  G  ++ +
Sbjct: 1971 SPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWAD 2027

Query: 1887 NTCTRLCTCSVHN-NITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDG 1944
             TC++ C C     ++ C  ++C   ++C  L  G   C+      CQ  G+ HYV+ DG
Sbjct: 2028 GTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 2087

Query: 1945 SNHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
                    C  +L   CH P +    F ++  +E   G         V + IY+  +TL 
Sbjct: 2088 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLS 2146

Query: 2004 KG--HRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTT 2060
                 ++ ++   V LP  +  +    +  + +  +V    G+ + FDG+  + + +P  
Sbjct: 2147 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAA 2204

Query: 2061 YYGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117
            Y   +CG+CGN+N +  D+L     + A      ++       K     C          
Sbjct: 2205 YAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP-------- 2256

Query: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
              EQQE+  G      +        +A   P+ A C   +    +   C    C+  G  
Sbjct: 2257 --EQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP 2305

Query: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
              LC A+  + A CQ+ G +   WR   FCPL+CPA+S Y  C  SC  SC  L    EG
Sbjct: 2306 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EG 2364

Query: 2238 AKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG-CTEKCVC-T 2295
             +  SAC EGC+C  G+VLS D CVP  QCGC    G   PLG+ +     C  +C C  
Sbjct: 2365 CE--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DGRYYPLGEVFYPGPECERRCECGP 2421

Query: 2296 GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTY 2355
            GG + C +     G H +   ++    C +    +C   G   Y+T DG  Y L G  +Y
Sbjct: 2422 GGHVTCQE-GAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY 2480

Query: 2356 VLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKM 2415
            VL +     P   +  +V  +N          LQ ++ TV G  V L  G ++ V+ + +
Sbjct: 2481 VLAQVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVAGQVVSLAQGQQVTVDGEAV 2534

Query: 2416 AVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNR 2475
            A+P      +RVT  G+ + L T   L + F G  + ++S+PS + G + GLCGN++ N 
Sbjct: 2535 ALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 2593

Query: 2476 KNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECS 2535
             +D +LP+G+   ++ TFG +W               P   +G G   G + G  V  C 
Sbjct: 2594 SDDFVLPNGSAASSVETFGAAWRA-------------PGSSKGCGEGCGPQ-GCPV--CL 2637

Query: 2536 PEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVL 2594
             E+ A   S +AC  L +PQGPFA C   ++P  +   CV DLC+    +  +   C+ L
Sbjct: 2638 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSL 2694

Query: 2595 SGYAILCQEAGAALAGWRDRTLCESPC 2621
            + Y   CQ AG A+  WR  + C   C
Sbjct: 2695 AAYTAACQAAGVAVKPWRTDSFCPLHC 2721



 Score =  838 bits (2165), Expect = 0.0
 Identities = 536/1676 (31%), Positives = 767/1676 (45%), Gaps = 125/1676 (7%)

Query: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
            +S +A +     + +G   +  +    CP N+RYE C  ACP SC    +P    G  C 
Sbjct: 718  LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 777

Query: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
            EGCVC PGF+ S   C+ ASSC C +      PG E W    C   C C   + +V C+ 
Sbjct: 778  EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837

Query: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
             Q C     C ++NG  GC+P     TC   GDPHYV+FDGR F FMG CTY+L   CG 
Sbjct: 838  KQSCPAGERCSVQNGLLGCYP-DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 896

Query: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLK--GRRTLVGGQQVTLPAIPS 1245
            N+  P FRV  +NE +G + VS    V V      V + +    + LV      LP   +
Sbjct: 897  NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 956

Query: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
             G V +   GR   ++T+FGL V +D + ++   V S+Y+  LCGLCGN++G+  +D   
Sbjct: 957  DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1016

Query: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
              G  A +    GNSWQ  ++    C   +  + P  DS +   +     CG L D  GP
Sbjct: 1017 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074

Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
            F  C   +        C+ D C   G    LC  ++T    CQ AG  V PWR    CP+
Sbjct: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134

Query: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
            +CPP+S Y  C+  CP +C        C   C E C C+ GF LSG  C+P + CGC+H 
Sbjct: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVH- 1193

Query: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
             G+Y   G+ +Y  PGC  LC C+    + C+   C   E C    G  GC A G++TC 
Sbjct: 1194 QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1253

Query: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
            ASGDPHY TFDG    FMGTC YVL + C +R     F V   N   G G + V+ +  V
Sbjct: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313

Query: 1603 HVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSH 1662
             V  F L +   R  KV +NG  + LPV LA G++      + V++ T+FGL+V YD  +
Sbjct: 1314 QVANFTLRLE-QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVY 1372

Query: 1663 LVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWK--LPES------ 1714
             V VTVP +Y  Q+CGLCGNYN +  DD  +P+   AG++ + G +W+  +P+S      
Sbjct: 1373 YVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT 1432

Query: 1715 -SEPG---CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVH 1770
               PG   C      P   ++    + +   C +L +P GP S CH++V PQ     C+ 
Sbjct: 1433 PCPPGSEDCIPSHKCPPELEKKYQKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIF 1489

Query: 1771 GQCGTKGDTTALCRSLQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
              C   G+ + LC ++ AY S C A  G    WR  TFCPM CPP S Y  C+  C   C
Sbjct: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549

Query: 1830 SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTC 1889
            S+++ P  C     CAE C+C  G + +G +CVP+ QCGC      Y P  E+    + C
Sbjct: 1550 SALSAPPQCQDG--CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNC 1605

Query: 1890 TRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC------------------RASGVGV- 1930
             + CTC     + C + +CKP Q+C    G+L C                     G GV 
Sbjct: 1606 RQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665

Query: 1931 -------CQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEE 1980
                   C L G+ HY SFDG        C  VL     P ++   L  F ++ K++   
Sbjct: 1666 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NR 1724

Query: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGH----RVLINSKQVTLPAISQIPGVSVKSSSIYSI 2036
            G      +  V +      +++ K      RV +N     LP       +SV   +  ++
Sbjct: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKAL 1784

Query: 2037 VNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVN 2096
            +    G+QV +D N  +++ +P++Y+G VCG+CGN +    ++ + P+  +A S   +  
Sbjct: 1785 LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1844

Query: 2097 SWKDKDIDP----SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQ 2152
            SW+    DP     C+       +   EQ E P G C             A+     +  
Sbjct: 1845 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGP-GFCGPL----------ASGTGGPFTT 1893

Query: 2153 CASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECP 2212
            C + +    F   C   +C  GG    LC+AL ++ A CQ+ G+    WR    C + CP
Sbjct: 1894 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP 1953

Query: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKD 2271
              S Y  C P C  SC         A     C EGC C  G+VLS D+CVP  + CGC  
Sbjct: 1954 ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW- 2012

Query: 2272 AHGGSIPLGKS-WVSSGCTEKCVC--TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKS 2328
            A+G     G   W    C++ C C   GG++ C    C  G  C L     +  C    +
Sbjct: 2013 ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVST 2071

Query: 2329 EQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFL 2388
             +C  +GDP Y+T DG  +  QG   Y+L       P G E   V   N+    ++  + 
Sbjct: 2072 AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYT 2131

Query: 2389 QEVITTVYGYKVQLQA--GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSF 2446
            + V   +Y + + L A    +L V+   +A+P++ +  L   L G  + + T   L ++F
Sbjct: 2132 RSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAF 2191

Query: 2447 GGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALL 2506
             G     + +P+ Y   + GLCGNY+++  +D+    G            W+V       
Sbjct: 2192 DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQV------- 2236

Query: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVA 2565
                      +G G  +        S C+PEQ  S     AC V++   GP A CH  V 
Sbjct: 2237 -------GGAQGCGECVSKPC---PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVP 2286

Query: 2566 PEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            P  + + C+LD C  Q         C  ++ Y   CQ AGA L  WR    C   C
Sbjct: 2287 PAQYFQGCLLDACQVQG---HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQC 2339



 Score =  812 bits (2098), Expect = 0.0
 Identities = 502/1553 (32%), Positives = 729/1553 (46%), Gaps = 96/1553 (6%)

Query: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
            C+  QC     CQ+  G+ GC   + TA C   GDPHY TFDGR +  MG C+Y + + C
Sbjct: 444  CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502

Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
              + T P F V AKNE +G   VS +  V V     +V+L +G     LV  Q+  LP  
Sbjct: 503  SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562

Query: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
             S+G + +  SG    ++  FGL V +D D QL +++ + +  ++CGLCGNY+G+  +D 
Sbjct: 563  LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622

Query: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
            L  DG+ A D  E  +SW+ D D D  C+     N P+C         G   CG L    
Sbjct: 623  LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681

Query: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
            GPF  C   +    F + C+ D+C   G +  LC  +S     C + G +V  WR P  C
Sbjct: 682  GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741

Query: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
            P++CP NS+Y LC   CP +C+   +   CS R CVE C C PGFV SG  C+P S CGC
Sbjct: 742  PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801

Query: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
                       E W    C+  C C  + +++ C+  + C A E C  Q+G+ GC+    
Sbjct: 802  TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861

Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
             TC  SGDPHY++FDG    FMGTCTY+L   C   +    F V   NE+RG    VSY 
Sbjct: 862  GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 920

Query: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
            +AV V    + +++ R    +V+++     LP   A G+V +       ++ T+FGL V 
Sbjct: 921  RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 980

Query: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
            YD +  V   VPSSY   LCGLCGN+N +  DD        A +++  G +W+  E + P
Sbjct: 981  YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1038

Query: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
            GC     +P  C +     A    +KN C IL +P+GPF +CH  + PQ +   CV+ +C
Sbjct: 1039 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096

Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
               G +  LC +L  YA+ C  AG     WR+   CP+ CPP S Y  CS  CP +C  +
Sbjct: 1097 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1156

Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
              P  C     C E C C +G  LSG SC+PL  CGC    G+YHP G+ +Y    C  L
Sbjct: 1157 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1213

Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
            C C     ++C  S+C P++ C    G L C A G   CQ  G+ HY +FDG        
Sbjct: 1214 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1273

Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
            C  VL + C     L  F +  ++     G     R+  V +  +  ++  Q+  +V +N
Sbjct: 1274 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 1332

Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
               + LP +     +         ++    G++V +D  + + + +P  YY ++CG+CGN
Sbjct: 1333 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGN 1392

Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
            +N + +D+   P+   A + +EF NSW++   D  C   L      P  +   PS  C  
Sbjct: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC-P 1448

Query: 2132 ADLRRAREKCE--AALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
             +L +  +K E    L +P    + C   +D    L DC   LC  GG    LC  + A+
Sbjct: 1449 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 1508

Query: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSACA 2245
             + CQ+ G     WR  +FCP+ECP  S Y  C  +CS  C  L    +C+       CA
Sbjct: 1509 VSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQ-----DGCA 1563

Query: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDF 2304
            EGC C  G++ +   CVP  QCGC   +G      ++ +   C ++C C  G  + C + 
Sbjct: 1564 EGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH 1622

Query: 2305 RCPSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPRYL 2340
             C  G  CQ        +T D                     C+ +    C ++GDP Y 
Sbjct: 1623 SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYH 1682

Query: 2341 TFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGY 2398
            +FDG  +  QG   YVL  T    V  +G+ P  V  +N+     +  +++ V     G 
Sbjct: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGT 1742

Query: 2399 KVQLQ----AGLELVVNNQKMAVPYR-PNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAV 2453
             + +       + + VN    A+P    +  + V     +  LV DF L VS+       
Sbjct: 1743 NISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVD 1802

Query: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
            ++LPS Y G V GLCGN D+N  ND + P+G L  ++  +G SW     D L        
Sbjct: 1803 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL-------- 1854

Query: 2514 AEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLAD-PQGPFAACHQTVAPEPFQE 2571
              +E +G+            C  ++L        C  LA    GPF  CH  V PE F +
Sbjct: 1855 CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFK 1905

Query: 2572 HCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQN 2624
             CVLD+C     R   ++ C+ L+ Y   CQ AG  +  WR +  CE  C +N
Sbjct: 1906 GCVLDVCMGGGDR---DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPEN 1955



 Score =  753 bits (1944), Expect = 0.0
 Identities = 484/1504 (32%), Positives = 698/1504 (46%), Gaps = 122/1504 (8%)

Query: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
            CPPN+ YE CA  C   C   S  P C   C EGC C+ GFL++   C+    C C++N 
Sbjct: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591

Query: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
             YYEP       NC + C C  G  + CQ   C    VCQ   G   C    P  G    
Sbjct: 1592 VYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 1651

Query: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
                               ATC ++GDPHY +FDGR F F G C Y+LA   C G ST  
Sbjct: 1652 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 1711

Query: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR----RTLVGGQQVTLPAIPSK 1246
               F VT KN+ +G   VS +  V V    + +++ K      R  V G    LP   + 
Sbjct: 1712 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVAD 1771

Query: 1247 GVFLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
            G    A G    L   +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +  
Sbjct: 1772 GRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 1831

Query: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
            +G+ A      G SW+     D  C      + P+C         GPGFCG L   T GP
Sbjct: 1832 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGP 1890

Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
            F TC  HV   SFF  C+LD+C   G + +LC  +++    CQ AG  ++ WR    C +
Sbjct: 1891 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1950

Query: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
             CP NS Y +C  PCP +C S     +   C   CVE C+C+ GFVLS   C+P +  CG
Sbjct: 1951 TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 2010

Query: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
            C    G+Y + G  ++  G C + C C      + C P  C   E CG    G +GC   
Sbjct: 2011 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 2069

Query: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
              A C A GDPHY+T DG    F GTC Y+L+ PC      +  F V+  NE+RG    V
Sbjct: 2070 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 2128

Query: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
            SY ++V + +++ S++L      K+ ++G  VALP  L    +   LS   V++ T  GL
Sbjct: 2129 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGL 2187

Query: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
             + +DG   V + VP++Y   LCGLCGNYN +  DD      K AG   Q+G A    E 
Sbjct: 2188 SLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 2245

Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
                C      PS C           + C ++    GP + CH +VPP   F  C+   C
Sbjct: 2246 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2299

Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
              +G    LC ++  Y + C  AG Q   WR   FCP++CP  S Y  C   CP +C S+
Sbjct: 2300 QVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSL 2359

Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
            + P  C  A  C E C C  G +LSG +CVP+GQCGC    G Y+P+GE +Y    C R 
Sbjct: 2360 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERR 2416

Query: 1893 CTCSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPD 1951
            C C    ++TC + + C P++ C   DG+  C A+G G C   G  HY++ DG  + +  
Sbjct: 2417 CECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHG 2476

Query: 1952 ACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
            +C+ VL +VCHP      F I    EK   G     L  + + +    V+L +G +V ++
Sbjct: 2477 SCSYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQGQQVTVD 2530

Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
             + V LP    +  V V +     ++    G+++ FDG+  L + IP+ + G++CG+CGN
Sbjct: 2531 GEAVALPVA--VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGN 2588

Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQIPAEQQE 2123
            FN    D+ ++P+   A+S   F  +W+       C          + + E+  P E  E
Sbjct: 2589 FNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNE 2648

Query: 2124 NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQA 2183
                      LR  +           +A C + +  + +   C   LC   G    LC++
Sbjct: 2649 ------ACGQLRNPQGP---------FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRS 2693

Query: 2184 LQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSA 2243
            L A+ A CQ+ G+    WR  SFCPL CPA+S Y+ C  +C  SC  L G        + 
Sbjct: 2694 LAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL---TGCTTR 2750

Query: 2244 CAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA-IQCG 2302
            C EGC C   ++LS+  C+P   CGC   +G  +P+  S ++S C+E+C C+  + + C 
Sbjct: 2751 CFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 2809

Query: 2303 DFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVL 2357
               CP G  C++ ++  N       CV       + +   R  T     Y L  R    L
Sbjct: 2810 AAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP-GL 2868

Query: 2358 IKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMA- 2416
              T+       E  +  G+ +    +  IF Q+ + T+   K     GL + +  +K+A 
Sbjct: 2869 QNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLAS 2927

Query: 2417 --VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKN 2474
              V   P+  L V              + V  G      + + + + G + G CGN+D +
Sbjct: 2928 VSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGD 2978

Query: 2475 RKND 2478
            + ND
Sbjct: 2979 QTND 2982



 Score =  646 bits (1667), Expect = 0.0
 Identities = 392/1088 (36%), Positives = 549/1088 (50%), Gaps = 63/1088 (5%)

Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
            CP N+ YE C   CPASC SP P   P      C EGC C+ GF+ S + C+  ++ C C
Sbjct: 1952 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2011

Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
            + N  Y+E G+E W    C++ CRC PG   + C  + CG   VC L  +GQ+GC P + 
Sbjct: 2012 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 2070

Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
            TA C  +GDPHYVT DG  F F G C Y+L+ PC         F VT  NE +G + VS 
Sbjct: 2071 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 2130

Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
               V + +   ++TL     R+  V G  V LP      +    SG  V + T  GL + 
Sbjct: 2131 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 2190

Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
            +DGD  + + V + Y+  LCGLCGNY+ +  +D   + G PAG        WQ      Q
Sbjct: 2191 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 2240

Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
             C +      PS C    Q S  GP  CG +  T GP   C   V  A +F  C+LD C 
Sbjct: 2241 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 2300

Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
             QG    LC  ++T    CQ AG  +  WR P FCP+ CP +S Y LC   CP +C S  
Sbjct: 2301 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 2360

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
            +   C   C E C C+ GFVLSG  C+P  QCGCLH  G Y+ +GE +Y  P C+  C C
Sbjct: 2361 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 2419

Query: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
                 + CQ    C   E C  +DG+  CHA G   C A+G  HY+T DG ++   G+C+
Sbjct: 2420 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 2479

Query: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
            YVL + C  +  D  F +    +N  G L+      + VTV    +SL +G +V ++G  
Sbjct: 2480 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 2533

Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
            VALPV  A GRV +      ++L T  GL++ +DG   + +++PS + G+LCGLCGN+N 
Sbjct: 2534 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 2591

Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
            N  DD + P+   A      GAAW+ P SS+ GC   G  P  C     E +     N+ 
Sbjct: 2592 NWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 2649

Query: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
            C  L NPQGPF+ C  V+ P   F  CV+  C  KGD   LCRSL AY + C  AG A  
Sbjct: 2650 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 2709

Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
             WR  +FCP+ CP  S YS C+  C  +C++++    C     C E CEC    +LS   
Sbjct: 2710 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 2767

Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
            C+P+  CGCT   G Y PV     T + C+  C+CS  + +TC  + C P ++C      
Sbjct: 2768 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 2825

Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
              C A+  G+C L   ++  +FDG+  +        L   C P +   +P++++ A+ + 
Sbjct: 2826 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 2883

Query: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
              G TEA  + +V+I   D  VTL     V +N  +V LPA  ++  VSV  +   S +V
Sbjct: 2884 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 2940

Query: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
              K GVQV    N  + + +   + GK+CG CGNF+ ++ ++     ++ A      +  
Sbjct: 2941 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 2994

Query: 2098 WKDKDIDP 2105
            W+ +D  P
Sbjct: 2995 WRAQDFSP 3002



 Score =  376 bits (965), Expect = e-103
 Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)

Query: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
            +CP ++ YE C  +CP SC   S    C   CREGCVC+ GF+ S + C+    C C ++
Sbjct: 2338 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 2397

Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
              YY  G  ++  P C   C C PG  V CQ  + CG H  C+L++G   CH   G   C
Sbjct: 2398 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 2456

Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
            L  G  HY+T DGR +   G C+Y+LAQ C     D  F +  +    G      L ++ 
Sbjct: 2457 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 2511

Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
            VT+    V+L +G++  V G+ V LP    + V + A GR + LQT  GLR+ +DGD  L
Sbjct: 2512 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 2570

Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
             +++ S + G+LCGLCGN++GN  +D +  +GS A   E  G +W+         +    
Sbjct: 2571 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 2630

Query: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
               P C +   +       CG+L +  GPF TC   +  + +F  C+ D+C  +G +  L
Sbjct: 2631 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 2690

Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
            C  ++  T  CQ AG AVKPWR   FCP+ CP +S YS+C + C  +C   SG +G  C+
Sbjct: 2691 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 2748

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
             RC E CEC+  F+LS   CIP   CGC H  G Y  V        C E C C S++ + 
Sbjct: 2749 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 2807

Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
            CQ   C     C  +     C A     C  S   +  TFDGA         Y L+  C 
Sbjct: 2808 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 2866

Query: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
                +   Y VV+      G   +   +  VH+   D  ++L     V +NG RV LP  
Sbjct: 2867 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 2923

Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
                    R     +L+    G+QV    +  V V V + + G+LCG CGN++ +  +D
Sbjct: 2924 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 2982



 Score =  326 bits (836), Expect = 2e-88
 Identities = 220/739 (29%), Positives = 330/739 (44%), Gaps = 64/739 (8%)

Query: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
            +C    C   Q C  + G   C A    VC+  G+ HY +FDG  + +   C+  +V++C
Sbjct: 443  SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502

Query: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPA 2019
                 LP F + AK+E   G      +  V +  Y   V+L +G    VL+++++  LP 
Sbjct: 503  SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561

Query: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
                  + V  S   ++V +  G+ V +D +  L + +P  +  +VCG+CGN+N +  D+
Sbjct: 562  SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621

Query: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
             + P   +A    EF +SWK  D D  C+     +   PA    Q ++  G+     L +
Sbjct: 622  FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 679

Query: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
                    L  P +A C   +D  PFL  C   LC  GG   +LC+ L A+   C   G+
Sbjct: 680  --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 730

Query: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
                WR+ + CPL CPA S Y  C P+C  S       C GA  PS      C EGC+C 
Sbjct: 731  SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 783

Query: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
            PG+V S   CVP S CGC        P  + W    C  +C C G    + C D + CP+
Sbjct: 784  PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843

Query: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
            G  C +   N    C  D+   C   GDP Y++FDG  +   G  TY+L+ +      LP
Sbjct: 844  GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 901

Query: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
                 +LVE  ++     S  + + V     G KV ++     +++V++    +P++  +
Sbjct: 902  --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957

Query: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
              ++V   G+   + TDF L V++         +PS Y   + GLCGN++ +  +D+ L 
Sbjct: 958  GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017

Query: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
             G    N   FGNSW+ +T            A E G   +L      Q+           
Sbjct: 1018 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1060

Query: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQ 2602
            S   C +LADP+GPF  CH  + P+     CV D C    P +   L C  L+ YA  CQ
Sbjct: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1117

Query: 2603 EAGAALAGWRDRTLCESPC 2621
             AGA +  WR   LC   C
Sbjct: 1118 AAGATVHPWRSEELCPLSC 1136


>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 1403

 Score =  686 bits (1769), Expect = 0.0
 Identities = 448/1396 (32%), Positives = 653/1396 (46%), Gaps = 104/1396 (7%)

Query: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP- 1185
            C    C     C+ + GQ  C P    ATC ++GDPHY +FDGR F F G C Y+LA   
Sbjct: 47   CHGVTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105

Query: 1186 -CGNSTDPF--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTL 1240
              G ST     F VT KNE +G   VS +  V V    + +++ K    +  V G    L
Sbjct: 106  CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165

Query: 1241 PAIPSKGVFLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSD 1299
            P   + G    A G    L   +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +
Sbjct: 166  PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225

Query: 1300 NDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLV 1359
            ND +  +G+ A      G SW+     D  C      + P+C         GPGFCG L 
Sbjct: 226  NDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 284

Query: 1360 D-THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWRE 1418
              T GPF TC  HV   SFF  C+LD+C   G   +LC  +++    CQ AG  ++ WR 
Sbjct: 285  PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344

Query: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSG---FSGMFCSDRCVEACECNPGFVLSGLECIP 1475
               C + CP NS Y +C  PCP +C S     +   C   CVE C+C+ GFVLS   C+P
Sbjct: 345  QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404

Query: 1476 -RSQCGCLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCG-QQDGI 1531
              + CGC    G+Y + G  ++  G C + C C      + C P  C   E CG    G 
Sbjct: 405  LNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ 463

Query: 1532 YGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENR 1590
            +GC     A C A GDPHY+T DG    F GTC Y+L+ PC      +  F V+  NE+R
Sbjct: 464  HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 523

Query: 1591 GGILEVSYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648
            G    VSY ++V + +++ S++L      K+ ++G  VALP  L    +   LS   V++
Sbjct: 524  GS-QAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVV 581

Query: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
             T  GL + +DG   V + VP++Y   LCGLCGNYN +  DD      K AG   Q+G A
Sbjct: 582  TTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGA 639

Query: 1709 WKLPESSEPGCFLVGGKPSSC-QENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFAS 1767
                E     C      PS C  E   +      C ++    GP + CH +VPP   F  
Sbjct: 640  QGCGECVSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQG 693

Query: 1768 CVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCP 1826
            C+   C  +G    LC ++  Y + C  AG Q   WR   FCP++CP  S Y  C   CP
Sbjct: 694  CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCP 753

Query: 1827 DTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886
             +C S++ P  C  A  C E C C  G +LSG +CVP+GQCGC    G Y+P+GE +Y  
Sbjct: 754  VSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPG 810

Query: 1887 NTCTRLCTCSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGS 1945
              C R C C    ++TC + + C P++ C   DG+  C A+G G C   G  HY++ DG 
Sbjct: 811  PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870

Query: 1946 NHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKG 2005
             + +  +C+ VL +VCHP      F I    EK   G     L  + + +    V+L +G
Sbjct: 871  VYDLHGSCSYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQG 924

Query: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKV 2065
             +V ++ + V LP    +  V V +     ++    G+++ FDG+  L + IP+ + G++
Sbjct: 925  QQVTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 982

Query: 2066 CGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQI 2117
            CG+CGNFN    D+ ++P+   A+S   F  +W+       C          + + E+  
Sbjct: 983  CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETA 1042

Query: 2118 PAEQQE------NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLC 2171
            P E  E      NP G                      +A C + +  + +   C   LC
Sbjct: 1043 PYESNEACGQLRNPQG---------------------PFATCQAVLSPSEYFRQCVYDLC 1081

Query: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231
               G    LC++L A+ A CQ+ G+    WR  SFCPL CPA+S Y+ C  +C  SC  L
Sbjct: 1082 AQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAAL 1141

Query: 2232 DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEK 2291
             G        + C EGC C   ++LS+  C+P   CGC   +G  +P+  S ++S C+E+
Sbjct: 1142 SGL---TGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSER 1197

Query: 2292 CVCTGGA-IQCGDFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGF 2345
            C C+  + + C    CP G  C++ ++  N       CV       + +   R  T    
Sbjct: 1198 CSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPG 1257

Query: 2346 SYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAG 2405
             Y L  R    L  T+       E  +  G+ +    +  IF Q+ + T+   K     G
Sbjct: 1258 VYELSSRCP-GLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNG 1315

Query: 2406 LELVVNNQKMA---VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEG 2462
            L + +  +K+A   V   P+  L V              + V  G      + + + + G
Sbjct: 1316 LRVDLPAEKLASVSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAG 1366

Query: 2463 LVSGLCGNYDKNRKND 2478
             + G CGN+D ++ ND
Sbjct: 1367 KLCGACGNFDGDQTND 1382



 Score =  647 bits (1669), Expect = 0.0
 Identities = 392/1088 (36%), Positives = 550/1088 (50%), Gaps = 63/1088 (5%)

Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
            CP N+ YE C   CPASC SP P   P      C EGC C+ GF+ S + C+  ++ C C
Sbjct: 352  CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 411

Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
            + N  Y+E G+E W    C++ CRC PG   + C  + CG   VC L  +GQ+GC P + 
Sbjct: 412  WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 470

Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
            TA C  +GDPHYVT DG  F F G C Y+L+ PC         F VT  NE +G + VS 
Sbjct: 471  TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 530

Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
               V + +   ++TL     R+  V G  V LP      +    SG  V + T  GL + 
Sbjct: 531  TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 590

Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
            +DGD  + + V + Y+  LCGLCGNY+ +  +D   + G PAG        WQ      Q
Sbjct: 591  FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 640

Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
             C +      PS C    Q S  GP  CG +  T GP   C   V  A +F  C+LD C 
Sbjct: 641  GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 700

Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
             QG    LC  ++T    CQ AG  +  WR P FCP+ CP +S Y LC   CP +C S  
Sbjct: 701  VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 760

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
            +   C   C E C C+ GFVLSG  C+P  QCGCLH  G Y+ +GE +Y  P C+  C C
Sbjct: 761  APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 819

Query: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
                 + CQ    C   E C  +DG+  CHA G   C A+G  HY+T DG ++   G+C+
Sbjct: 820  GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 879

Query: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
            YVL + C  +  D  F +    +N  G L+      + VTV    +SL +G +V ++G  
Sbjct: 880  YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 933

Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
            VALPV  A GRV +      ++L T  GL++ +DG   + +++PS + G+LCGLCGN+N 
Sbjct: 934  VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 991

Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
            N  DD + P+   A      GAAW++P SS+ GC   G  P  C     E +     N+ 
Sbjct: 992  NWSDDFVLPNGSAASSVETFGAAWRVPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 1049

Query: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
            C  L NPQGPF+ C  V+ P   F  CV+  C  KGD   LCRSL AY + C  AG A  
Sbjct: 1050 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 1109

Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
             WR  +FCP+ CP  S YS C+  C  +C++++    C     C E CEC    +LS   
Sbjct: 1110 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 1167

Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
            C+P+  CGCT   G Y PV     T + C+  C+CS  + +TC  + C P ++C      
Sbjct: 1168 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 1225

Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
              C A+  G+C L   ++  +FDG+  +        L   C P +   +P++++ A+ + 
Sbjct: 1226 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 1283

Query: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
              G TEA  + +V+I   D  VTL     V +N  +V LPA  ++  VSV  +   S +V
Sbjct: 1284 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 1340

Query: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
              K GVQV    N  + + +   + GK+CG CGNF+ ++ ++     ++ A      +  
Sbjct: 1341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 1394

Query: 2098 WKDKDIDP 2105
            W+ +D  P
Sbjct: 1395 WRAQDFSP 1402



 Score =  541 bits (1393), Expect = e-153
 Identities = 362/1133 (31%), Positives = 527/1133 (46%), Gaps = 83/1133 (7%)

Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL-TRPC 1572
            C    CR QE C +Q G   C     ATC   GDPHY +FDG    F GTC YVL T  C
Sbjct: 47   CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106

Query: 1573 WSRSQDSY--FVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRG--CKVMLNGHRVAL 1628
               S      F V+  NENRG    VSY++ V V     +IS+ +    KV +NG   AL
Sbjct: 107  LGVSTQGLTPFTVTTKNENRGNPA-VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165

Query: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL 1688
            PV +A GR+++   ++  LL  +FGLQV YD +  V+VT+PSSY G +CGLCGN + N  
Sbjct: 166  PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225

Query: 1689 DDNLRPDRKLAGDSMQLGAAWKLPESSEPGCF-LVGGKPSSCQENSMADAWNKNCAILIN 1747
            +D + P+  LA      G +W+ P   +P C+    G   +C E+ +           + 
Sbjct: 226  NDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 284

Query: 1748 PQ--GPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRN 1804
            P   GPF+ CH  VPP+S F  CV   C   GD   LC++L +Y + C  AG     WR 
Sbjct: 285  PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344

Query: 1805 RTFCPMRCPPGSSYSPCSSPCPDTCSS---INNPRDCPKALPCAESCECQKGHILSGTSC 1861
            +  C + CP  S Y  C  PCP +C S   +  P  C    PC E C+C  G +LS   C
Sbjct: 345  QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRC 402

Query: 1862 VPLGQ-CGCTDPAGSYHPVGERWYTENTCTRLCTCSVHN-NITCFQSTCKPNQICWAL-D 1918
            VPL   CGC    G+YH  G  ++ + TC++ C C     ++ C  ++C   ++C  L  
Sbjct: 403  VPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPS 461

Query: 1919 GLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCH-PAMALPFFKISAKHE 1977
            G   C+      CQ  G+ HYV+ DG        C  +L   CH P +    F ++  +E
Sbjct: 462  GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE 521

Query: 1978 KEEGGTEAFRLHEVYIDIYDAQVTLQKG--HRVLINSKQVTLP-AISQIPGVSVKSSSIY 2034
               G         V + IY+  +TL      ++ ++   V LP  +  +    +  + + 
Sbjct: 522  -HRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADV- 579

Query: 2035 SIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVAN---SD 2091
             +V    G+ + FDG+  + + +P  Y   +CG+CGN+N +  D+L     + A      
Sbjct: 580  -VVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGG 638

Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWA 2151
            ++       K     C            EQQE+  G      +        +A   P+ A
Sbjct: 639  AQGCGECVSKPCPSPCTP----------EQQESFGGPDACGVI--------SATDGPL-A 679

Query: 2152 QCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLEC 2211
             C   +    +   C    C+  G    LC A+  + A CQ+ G +   WR   FCPL+C
Sbjct: 680  PCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQC 739

Query: 2212 PAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKD 2271
            PA+S Y  C  SC  SC  L    EG +  SAC EGC+C  G+VLS D CVP  QCGC  
Sbjct: 740  PAHSHYELCGDSCPVSCPSLSAP-EGCE--SACREGCVCDAGFVLSGDTCVPVGQCGCLH 796

Query: 2272 AHGGSIPLGKSWVSSG-CTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
              G   PLG+ +     C  +C C  GG + C +     G H +   ++    C +    
Sbjct: 797  -DGRYYPLGEVFYPGPECERRCECGPGGHVTCQE-GAACGPHEECRLEDGVQACHATGCG 854

Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQ 2389
            +C   G   Y+T DG  Y L G  +YVL +     P   +  +V  +N          LQ
Sbjct: 855  RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD------LQ 908

Query: 2390 EVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGR 2449
             ++ TV G  V L  G ++ V+ + +A+P      +RVT  G+ + L T   L + F G 
Sbjct: 909  RLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGD 967

Query: 2450 KNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFP 2509
             + ++S+PS + G + GLCGN++ N  +D +LP+G+   ++ TFG +W V          
Sbjct: 968  AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRV---------- 1017

Query: 2510 RAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEP 2568
               P   +G G   G + G  V  C  E+ A   S +AC  L +PQGPFA C   ++P  
Sbjct: 1018 ---PGSSKGCGEGCGPQ-GCPV--CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071

Query: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            +   CV DLC+    +  +   C+ L+ Y   CQ AG A+  WR  + C   C
Sbjct: 1072 YFRQCVYDLCA---QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121



 Score =  376 bits (965), Expect = e-103
 Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)

Query: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
            +CP ++ YE C  +CP SC   S    C   CREGCVC+ GF+ S + C+    C C ++
Sbjct: 738  QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 797

Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
              YY  G  ++  P C   C C PG  V CQ  + CG H  C+L++G   CH   G   C
Sbjct: 798  GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 856

Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
            L  G  HY+T DGR +   G C+Y+LAQ C     D  F +  +    G      L ++ 
Sbjct: 857  LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 911

Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
            VT+    V+L +G++  V G+ V LP    + V + A GR + LQT  GLR+ +DGD  L
Sbjct: 912  VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 970

Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
             +++ S + G+LCGLCGN++GN  +D +  +GS A   E  G +W+         +    
Sbjct: 971  LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGP 1030

Query: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
               P C +   +       CG+L +  GPF TC   +  + +F  C+ D+C  +G +  L
Sbjct: 1031 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 1090

Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
            C  ++  T  CQ AG AVKPWR   FCP+ CP +S YS+C + C  +C   SG +G  C+
Sbjct: 1091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 1148

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
             RC E CEC+  F+LS   CIP   CGC H  G Y  V        C E C C S++ + 
Sbjct: 1149 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 1207

Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
            CQ   C     C  +     C A     C  S   +  TFDGA         Y L+  C 
Sbjct: 1208 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 1266

Query: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
                +   Y VV+      G   +   +  VH+   D  ++L     V +NG RV LP  
Sbjct: 1267 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 1323

Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
                    R     +L+    G+QV    +  V V V + + G+LCG CGN++ +  +D
Sbjct: 1324 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 1382



 Score =  133 bits (335), Expect = 2e-30
 Identities = 91/309 (29%), Positives = 137/309 (44%), Gaps = 27/309 (8%)

Query: 2323 CVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMD 2380
            C+ +    C ++GDP Y +FDG  +  QG   YVL  T  + V  +G+ P  V  +N+  
Sbjct: 67   CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR 126

Query: 2381 PPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLV 2437
               +  +++ V     G  + +      ++ VN    A+P    +  + V     +  LV
Sbjct: 127  GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLV 186

Query: 2438 TDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497
             DF L VS+       ++LPS Y G V GLCGN D+N  ND + P+G L  ++  +G SW
Sbjct: 187  ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 246

Query: 2498 EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLA-DPQG 2555
                 D L          +E +G+            C  ++L        C  LA    G
Sbjct: 247  RAPGWDPL--------CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGG 289

Query: 2556 PFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRT 2615
            PF  CH  V PE F + CVLD+C         ++ C+ L+ Y   CQ AG  +  WR + 
Sbjct: 290  PFTTCHAHVPPESFFKGCVLDVCMGGG---DHDILCKALASYVAACQAAGVVIEDWRAQV 346

Query: 2616 LCESPCLQN 2624
             CE  C +N
Sbjct: 347  GCEITCPEN 355


>gi|134268640 tectorin alpha precursor [Homo sapiens]
          Length = 2155

 Score =  654 bits (1687), Expect = 0.0
 Identities = 454/1577 (28%), Positives = 706/1577 (44%), Gaps = 98/1577 (6%)

Query: 1108 WFSPNCTEHCRCWP-GSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVT 1166
            W   NCT  CRC    + + CQ + C  + VC+ K   + C     T+TC+V+G+PHY T
Sbjct: 274  WDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE-TSTCVVFGEPHYHT 332

Query: 1167 FDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTL 1225
            FDG  F F G C Y+LA+ C   S+ PFF V AKNE +    VS + ++ V +    + +
Sbjct: 333  FDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILI 392

Query: 1226 LKGR--RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSST 1282
             KG   R  V     +LP     G V +  SG    ++T+FGL V +DG     ++V  +
Sbjct: 393  PKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGS 452

Query: 1283 YSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCD 1342
            Y    CGLCGNY+ N  +D L+ DG PA    +LG SW+     D +C    V N   CD
Sbjct: 453  YINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRV-YHADWKCDSGCVDNCTQCD 511

Query: 1343 SSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTM 1402
            ++ ++   G  +CG L  T GP   C   V   +F  SC+ D+C  +    LLC  +   
Sbjct: 512  AATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAY 571

Query: 1403 TTTCQDAGHAVKPWREPHFC--PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEAC 1460
               CQ  G  +  WR    C   + CP  S YS+C   CPDTC    +   C+  C E C
Sbjct: 572  ALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGC 631

Query: 1461 ECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGE-RWYKPGCKELCVCESNNRIRCQPWRC 1519
            ECN GFVLS  +C+P  +CGC    G Y+ +GE  W    C   C+CE    + C    C
Sbjct: 632  ECNQGFVLSTSQCVPLHKCGCDFD-GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTC 690

Query: 1520 RAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS 1579
             + E C  +DG  GC  +    C  S +    TFDGA + F    +Y L + C  R +  
Sbjct: 691  GSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYL 750

Query: 1580 YFVVSATNENRGGILEVSYIKAVHVTVFDLSISL--LRGCKVMLNGHRVALPVWLAQGRV 1637
               ++    + G     ++++ + + V D  + +  +   +V LNG  V LP +   G++
Sbjct: 751  EIDINKKKPDAG----PAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKL 806

Query: 1638 TIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
             I  + N   + +   + V+Y    L+ + + ++Y     GLCG YN N+ D+   P+ K
Sbjct: 807  EIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGK 866

Query: 1698 LAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKN---CAILINP-QGPFS 1753
               +      +W   E    G    G    +C  +S    + ++   C I+ +P    F 
Sbjct: 867  CTDNLAVFLESWTTFEEICNG--ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFL 924

Query: 1754 QCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRC 1812
            +CH VV   + + +C+   C + G+ + LC S+  YAS C  A  +   WR   FCP+ C
Sbjct: 925  ECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984

Query: 1813 PPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDP 1872
            P  S +  C + C +TC ++     C  +  C+E C+C +G+ L G+ CV   +CGC + 
Sbjct: 985  PENSHFEECIT-CTETCETLTLGPICVDS--CSEGCQCDEGYALLGSQCVTRSECGC-NF 1040

Query: 1873 AGSYHPVGERWYTENTCTRLCTCS-VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVC 1931
             G      E ++ +  C   C CS   N + C    CK ++ C    GL  C+A     C
Sbjct: 1041 EGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASC 1100

Query: 1932 QLPGESHYVSFDGSNHSIPDACTLVLVKV-CHPAM-ALPFFKISAKHEKEEGGTEAFRLH 1989
             + G  HY++FDG       +C L+L      P+  + P F ++AK+E  +    A  + 
Sbjct: 1101 IVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSL-ALWVK 1159

Query: 1990 EVYIDIYDAQVTLQKG--HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF 2047
            +V + ++   + + +   H VL+NS+++ LP       +++ S   + +V    G++V +
Sbjct: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219

Query: 2048 DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSC 2107
            D    L I +P +      G+CG +N   +D+L MP   +A+S +EF  SW  +  D  C
Sbjct: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKR--DTFC 1277

Query: 2108 QSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA 2167
            Q    D     A+ +    G  +   L        AA     +++C S+++ T F  +C 
Sbjct: 1278 QVGCGDRCPSCAKVE----GFSKVQQLCSLIPNQNAA-----FSKCHSKVNPTFFYKNCL 1328

Query: 2168 NTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPS 2227
               C  GG  Q  C  LQ + +TCQ+QG+    WRN + C + CP  S Y +C+  C P 
Sbjct: 1329 FDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPR 1388

Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
            C  +  + + +     C EGC C  GYVL+   C+    CGC        P    W +S 
Sbjct: 1389 CAAIRLKSDCSHY---CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSD 1444

Query: 2288 CTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFS 2346
            CT +C C     IQC   +C S   C L   N    C S K+  C   G   + TFDG  
Sbjct: 1445 CTRRCRCFRRNVIQCDPRQCKSDEECALR--NGVRGCFSTKTSYCLAAGGGVFRTFDGAF 1502

Query: 2347 YRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGY----KVQL 2402
             R      +VL      LP+ +   L+   +K   P  +I     I+ VY Y    ++ +
Sbjct: 1503 LRFPANCAFVLSTICQKLPD-ISFQLIINFDKWSAPNLTI-----ISPVYFYINEEQILI 1556

Query: 2403 QAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDF--ELVVSFGGRKNAVISLPSMY 2460
                 + VN  ++ VP+     L   ++    +LV D   ++ + + G     IS+    
Sbjct: 1557 NDRNTVKVNGTQVNVPFITG--LATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERL 1614

Query: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
            +  V GLCGN++ +  +D +   G    +      SW+    + + + P A    E    
Sbjct: 1615 QNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKT---NGMQKRPLAPSCNE---- 1667

Query: 2521 AELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCS 2579
                L+     + C    +        C  L D +G F  C+  + P PF E C LD C 
Sbjct: 1668 ----LQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCY 1723

Query: 2580 AQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLC----ESPCLQNPCQNDGQCREQ 2635
            +     ++   C  L+ Y   C+  G     W ++  C    E PC+   C N       
Sbjct: 1724 S----HKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNR------ 1773

Query: 2636 GATFTCECEVGYGGGLC 2652
                   CE+G G  LC
Sbjct: 1774 ------TCELGNGRELC 1784



 Score =  547 bits (1409), Expect = e-155
 Identities = 360/1229 (29%), Positives = 563/1229 (45%), Gaps = 92/1229 (7%)

Query: 1466 FVLSGLECIPRSQCGCLHPAGSYFKVGER-WYKPGCKELCVC-ESNNRIRCQPWRCRAQE 1523
            F + G E  P + C      G + + GE  W    C   C C + NN I CQ   C   E
Sbjct: 247  FKVDGKEIDPANGCTS---RGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYE 303

Query: 1524 FCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVV 1583
             C  +   + C A   +TC   G+PHY TFDG L HF G+C Y+L R C   S   +F V
Sbjct: 304  VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363

Query: 1584 SATNENRGGILEVSYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRL 1641
             A NE+R G   VS++K + V V    I + +G   +V +N    +LPV L  G V I  
Sbjct: 364  EAKNEHRRGSA-VSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ 422

Query: 1642 SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGD 1701
            S     + T+FGL V +DG H   ++VP SY    CGLCGNYN N LDD LRPD + A  
Sbjct: 423  SGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMS 482

Query: 1702 SMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQ 1757
             + LG +W++  +    + GC       + C   + A  +  + C  L    GP  +C  
Sbjct: 483  VLDLGESWRVYHADWKCDSGCV---DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGT 539

Query: 1758 VVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFC--PMRCPP 1814
            VV P +   SCV+  C  + + T LC+++QAYA +C   G     WR +T C   ++CP 
Sbjct: 540  VVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPS 599

Query: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
             S YS C+S CPDTCS +   R+C  A PC E CEC +G +LS + CVPL +CGC D  G
Sbjct: 600  FSHYSVCTSSCPDTCSDLTASRNC--ATPCTEGCECNQGFVLSTSQCVPLHKCGC-DFDG 656

Query: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP 1934
             Y+ +GE ++    CT  C C    ++ CF  TC   ++C   DG   C      VC L 
Sbjct: 657  HYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLS 716

Query: 1935 GESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYID 1994
                  +FDG++++ P   +  L+K C       + +I    +K + G    R   + + 
Sbjct: 717  QNQVLHTFDGASYAFPSEFSYTLLKTCPERP--EYLEIDINKKKPDAGPAWLRGLRILVA 774

Query: 1995 IYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLE 2054
              + ++       V +N ++V LP       + +  +   + V  K  V V++    LL 
Sbjct: 775  DQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLY 834

Query: 2055 IEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK--DKDIDPSCQSLLV 2112
            I + TTY+    G+CG +N    DE  +P+ +  ++ + F+ SW   ++  +  C  LL 
Sbjct: 835  IRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLL- 893

Query: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAP---VWAQCASRIDLTPFLVDCANT 2169
                      +  + +       R+R +C   +  P    + +C   +++T +   C   
Sbjct: 894  ----------KACNNDSELLKFYRSRSRC-GIINDPSNSSFLECHGVVNVTAYYRTCLFR 942

Query: 2170 LCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCW 2229
            LC+ GG    LC ++  + + C++  ++   WR   FCPLECP  S +  C+ +C+ +C 
Sbjct: 943  LCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETCE 1001

Query: 2230 DLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKS-WVSSGC 2288
             L     G     +C+EGC C  GY L   +CV RS+CGC +  G  +   ++ WV   C
Sbjct: 1002 TL---TLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGC-NFEGHQLATNETFWVDLDC 1057

Query: 2289 TEKCVCTG--GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFS 2346
               C C+G    + C    C    +C    +     C +     C V G   YLTFDGF 
Sbjct: 1058 QIFCYCSGTDNRVHCETIPCKDDEYCM--EEGGLYYCQARTDASCIVSGYGHYLTFDGFP 1115

Query: 2347 YRLQGRMTYVLIKTVD-VLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAG 2405
            +  Q     +L  T      +     +V  +N+   P  ++++++V  TV+GY + +   
Sbjct: 1116 FDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRA 1175

Query: 2406 LE--LVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEG 2462
             +  ++VN++++ +P +  +  + +  +G  + + TDF L V +  +    I++P   + 
Sbjct: 1176 YKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQN 1235

Query: 2463 LVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAE 2522
               GLCG Y+ N  +D+ +P G L  ++N FG SW VK +                   +
Sbjct: 1236 STYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW-VKRDTF----------------CQ 1278

Query: 2523 LGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQD 2582
            +G   G +   C+  +  S   Q C ++ +    F+ CH  V P  F ++C+ D C    
Sbjct: 1279 VG--CGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCI--- 1333

Query: 2583 PREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQND--GQCREQGATFT 2640
                 +  C  L  YA  CQ  G  + GWR+ T C   C  N         C+ + A   
Sbjct: 1334 DGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIR 1393

Query: 2641 ------------CECEVGY--GGGLCMEP 2655
                        C C+ GY   G  C+ P
Sbjct: 1394 LKSDCSHYCVEGCHCDAGYVLNGKSCILP 1422



 Score =  545 bits (1403), Expect = e-154
 Identities = 355/1201 (29%), Positives = 549/1201 (45%), Gaps = 57/1201 (4%)

Query: 1034 TTTSRSSTERCPPNARYESC--ACPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQ 1089
            T T   ST +CP  + Y  C  +CP +C     S  C   C EGC CN GF+ S + C+ 
Sbjct: 587  TQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVP 646

Query: 1090 ASSCNCFYNNDYYEPGA-EWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCH 1148
               C C ++  YY  G   W + NCT  C C  G  V C    CG+  VC +++G  GC 
Sbjct: 647  LHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCF 706

Query: 1149 PYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV 1208
            P   T  CL+  +    TFDG  + F  + +Y L + C     P +     N+++   G 
Sbjct: 707  PKRET-VCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER--PEYLEIDINKKKPDAGP 763

Query: 1209 SCLSKVYVTLPESTVTL--LKGRRTLVGGQQVTLPAI-PSKGVFLGASGRFVELQTEFGL 1265
            + L  + + + +  V +  +      + GQ+V LP   PS  + +  +     ++++  +
Sbjct: 764  AWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVV 823

Query: 1266 RVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
             V++     LY+ +S+TY     GLCG Y+ N+ ++    +G    +      SW T ++
Sbjct: 824  TVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEE 883

Query: 1326 E-DQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGPFETCLLHVKAASFFDSCML 1383
              + EC    ++ + + DS L         CG + D ++  F  C   V   +++ +C+ 
Sbjct: 884  ICNGECG--DLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLF 941

Query: 1384 DMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTC 1443
             +C   G +  LC  ++   + C++A   V PWR   FCP+ CP NS +  C   C +TC
Sbjct: 942  RLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC 1000

Query: 1444 HSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKEL 1503
             +   G  C D C E C+C+ G+ L G +C+ RS+CGC             W    C+  
Sbjct: 1001 ETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIF 1060

Query: 1504 CVCE-SNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
            C C  ++NR+ C+   C+  E+C ++ G+Y C A+  A+C  SG  HYLTFDG    F  
Sbjct: 1061 CYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQT 1120

Query: 1563 TCTYVLTRPCWSRSQDSY--FVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK-- 1618
            +C  +L       S DS+  FVV+A NE+R   L + ++K V VTVF  SI + R  K  
Sbjct: 1121 SCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLAL-WVKQVDVTVFGYSIVIHRAYKHT 1179

Query: 1619 VMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCG 1678
            V++N  R+ LP+ L QG++ I      V++ T+FGL+V YD    + +TVP S      G
Sbjct: 1180 VLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYG 1239

Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW-KLPESSEPGCFLVGGKPSSCQENSMADA 1737
            LCG YN N  DD   P   LA    + G +W K     + GC   G +  SC +      
Sbjct: 1240 LCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGC---GDRCPSCAKVEGFSK 1296

Query: 1738 WNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG 1797
              + C+++ N    FS+CH  V P   + +C+   C   G     C  LQ YAS C   G
Sbjct: 1297 VQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQG 1356

Query: 1798 -QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHIL 1856
                 WRN T C + CPP S Y  C S C   C++I    DC     C E C C  G++L
Sbjct: 1357 ITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHY--CVEGCHCDAGYVL 1414

Query: 1857 SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWA 1916
            +G SC+    CGC      Y P    W ++  CTR C C   N I C    CK ++ C  
Sbjct: 1415 NGKSCILPHSCGCYSDGKYYEPKQLFWNSD--CTRRCRCFRRNVIQCDPRQCKSDEECAL 1472

Query: 1917 LDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH 1976
             +G+  C ++    C   G   + +FDG+    P  C  VL  +C     +  F++    
Sbjct: 1473 RNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDIS-FQLIINF 1531

Query: 1977 EKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSI 2036
            +K         +  VY  I + Q+ +   + V +N  QV +P I+ +    + SS  + +
Sbjct: 1532 DKWSAPNLTI-ISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGL-ATKIYSSEGFLV 1589

Query: 2037 VNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVN 2096
            ++    +Q+ ++G ++++I I      KVCG+CGNFN +  D+ +    +   S      
Sbjct: 1590 IDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQ 1649

Query: 2097 SWK-----DKDIDPSCQSLLVDEQQIPAE----QQENPSGNC-RAADLRRAREKCEAALR 2146
            SWK      + + PSC  L   +     +    Q+    G C +  D++   + C   L 
Sbjct: 1650 SWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLL- 1708

Query: 2147 APVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF 2206
                       D  PF   C    C     +Q LC +L A+G  C+S G+    W     
Sbjct: 1709 -----------DPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKEN 1756

Query: 2207 C 2207
            C
Sbjct: 1757 C 1757



 Score =  209 bits (533), Expect = 2e-53
 Identities = 127/455 (27%), Positives = 202/455 (44%), Gaps = 41/455 (9%)

Query: 1039 SSTERCPPNARYESCA--CPASCKSPR--PSCGPLCREGCVCNPGFLFSDNHCIQASSCN 1094
            S T  CPPN+ YESC   C   C + R    C   C EGC C+ G++ +   CI   SC 
Sbjct: 1367 SCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCG 1426

Query: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154
            C+ +  YYEP   +++ +CT  CRC+  + ++C   QC +   C L+NG  GC     T+
Sbjct: 1427 CYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFS-TKTS 1485

Query: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214
             CL  G   + TFDG    F   C ++L+  C    D  F++    ++     ++ +S V
Sbjct: 1486 YCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPV 1545

Query: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274
            Y  + E  + +       V G QV +P I      + +S  F+ + T   +++ ++G   
Sbjct: 1546 YFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNV 1605

Query: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ----EC 1330
            + +++S     K+CGLCGN++G+  +D++ L G P      L  SW+T+  + +     C
Sbjct: 1606 IKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSC 1665

Query: 1331 QKYQVVN-SPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
             + Q    +  CD+     M G G+C +L D  G F+ C   +    F++SC LD C + 
Sbjct: 1666 NELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YS 1724

Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSG 1449
              +  LC  ++     C+  G     W E   C           +   PC         G
Sbjct: 1725 HKKFQLCGSLAAYGEACRSFGILSTEWIEKENCS---------GVVEDPC--------VG 1767

Query: 1450 MFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
              C +R    CE   G          R  CGC+ P
Sbjct: 1768 ADCPNR---TCELGNG----------RELCGCIEP 1789


>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 1472

 Score =  555 bits (1429), Expect = e-157
 Identities = 313/860 (36%), Positives = 433/860 (50%), Gaps = 24/860 (2%)

Query: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
            C+  QC     CQ+  G+ GC   + TA C   GDPHY TFDGR +  MG C+Y + + C
Sbjct: 505  CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563

Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
              + T P F V AKNE +G   VS +  V V     +V+L +G     LV  Q+  LP  
Sbjct: 564  SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 623

Query: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
             S+G + +  SG    ++  FGL V +D D QL +++ + +  ++CGLCGNY+G+  +D 
Sbjct: 624  LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 683

Query: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
            L  DG+ A D  E  +SW+ D D D  C+     N P+C         G   CG L    
Sbjct: 684  LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 742

Query: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
            GPF  C   +    F + C+ D+C   G +  LC  +S     C + G +V  WR P  C
Sbjct: 743  GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802

Query: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
            P++CP NS+Y LC   CP +C+   +   CS R CVE C C PGFV SG  C+P S CGC
Sbjct: 803  PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862

Query: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
                       E W    C+  C C  + +++ C+  + C A E C  Q+G+ GC+    
Sbjct: 863  TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 922

Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
             TC  SGDPHY++FDG    FMGTCTY+L   C   +    F V   NE+RG    VSY 
Sbjct: 923  GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 981

Query: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
            +AV V    + +++ R    +V+++     LP   A G+V +       ++ T+FGL V 
Sbjct: 982  RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041

Query: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
            YD +  V   VPSSY   LCGLCGN+N +  DD        A +++  G +W+  E + P
Sbjct: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1099

Query: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
            GC     +P  C +     A    +KN C IL +P+GPF +CH  + PQ +   CV+ +C
Sbjct: 1100 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1157

Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
               G +  LC +L  YA+ C  AG     WR+   CP+ CPP S Y  CS  CP +C  +
Sbjct: 1158 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1217

Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
              P  C     C E C C +G  LSG SC+PL  CGC    G+YHP G+ +Y    C  L
Sbjct: 1218 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1274

Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
            C C     ++C  S+C P++ C    G L C A G   CQ  G+ HY +FDG        
Sbjct: 1275 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1334

Query: 1953 CTLVLVKVCHPAMALPFFKI 1972
            C  VL + C     L  F +
Sbjct: 1335 CVYVLAQTCGTRPGLHRFAV 1354



 Score =  475 bits (1223), Expect = e-133
 Identities = 287/869 (33%), Positives = 416/869 (47%), Gaps = 43/869 (4%)

Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCW 1573
            C+  +C A + C    G  GC A+  A C A GDPHY TFDG  +  MGTC+Y +   C 
Sbjct: 505  CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564

Query: 1574 SRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK--VMLNGHRVALPVW 1631
                   F V A NE+RG    VSY+  V V  +  S+SL RG    V+++  R  LPV 
Sbjct: 565  EDDTLPAFSVEAKNEHRGS-RRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 623

Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDN 1691
            L++GR+ +  S    ++   FGL V YD    + +++P+ +  Q+CGLCGNYN +  DD 
Sbjct: 624  LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 683

Query: 1692 LRPDRKLAGDSMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKNCAILINP 1748
            L PD  LA D+++  ++WKL +     E GC      P+     +     ++ C +L   
Sbjct: 684  LTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTKL 741

Query: 1749 QGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF 1807
             GPF+ CH  + P+     CV+  C   G+  +LCR L AYA  C + G +   WR+   
Sbjct: 742  DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801

Query: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
            CP+ CP  S Y  C   CP +C+    P +C    PC E C C  G + SG +CVP   C
Sbjct: 802  CPLSCPANSRYELCGPACPTSCNGAAAPSNC-SGRPCVEGCVCLPGFVASGGACVPASSC 860

Query: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCS-VHNNITCF-QSTCKPNQICWALDGLLRCRA 1925
            GCT       P  E W  E  C R CTC+   + +TC  + +C   + C   +GLL C  
Sbjct: 861  GCTFQGLQLAPGQEVWADE-LCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919

Query: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
               G CQ  G+ HYVSFDG        CT +LV  C    ALP F++  ++E     T +
Sbjct: 920  DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 979

Query: 1986 FRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV 2043
            +    V ++    +V +++ +  +VL++     LP  +    V V      ++V    G+
Sbjct: 980  YT-RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 1038

Query: 2044 QVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDI 2103
             V +D N  +  ++P++Y   +CG+CGNFN +  D+L +     A +   F NSW++ + 
Sbjct: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE-ET 1097

Query: 2104 DPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVWAQCASRIDLTP 2161
             P C +          E  + P  +   A   +++ +C   A  + P + +C S++D   
Sbjct: 1098 RPGCGA---------TEPGDCPKLDSLVAQQLQSKNECGILADPKGP-FRECHSKLDPQG 1147

Query: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
             + DC    C   G    LC AL  + A CQ+ G     WR+   CPL CP +S Y  C 
Sbjct: 1148 AVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACS 1207

Query: 2222 PSCSPSCWDL--DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSI-P 2278
              C  SC DL   G C      S C EGC+C  G+ LS + C+P + CGC   H G+  P
Sbjct: 1208 YGCPLSCGDLPVPGGC-----GSECHEGCVCDEGFALSGESCLPLASCGC--VHQGTYHP 1260

Query: 2279 LGKS-WVSSGCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGD 2336
             G++ +   GC   C C  GG + C    C     CQ      +  CV+  S  C   GD
Sbjct: 1261 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQ--PSGGSLGCVAVGSSTCQASGD 1318

Query: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLP 2365
            P Y TFDG  +   G   YVL +T    P
Sbjct: 1319 PHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1347



 Score =  384 bits (986), Expect = e-106
 Identities = 228/631 (36%), Positives = 309/631 (48%), Gaps = 19/631 (3%)

Query: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
            +S +A +     + +G   +  +    CP N+RYE C  ACP SC    +P    G  C 
Sbjct: 779  LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 838

Query: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
            EGCVC PGF+ S   C+ ASSC C +      PG E W    C   C C   + +V C+ 
Sbjct: 839  EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 898

Query: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
             Q C     C ++NG  GC+P     TC   GDPHYV+FDGR F FMG CTY+L   CG 
Sbjct: 899  KQSCPAGERCSVQNGLLGCYPDR-FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 957

Query: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPS 1245
            N+  P FRV  +NE +G + VS    V V      V + +    + LV      LP   +
Sbjct: 958  NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 1017

Query: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
             G V +   GR   ++T+FGL V +D + ++   V S+Y+  LCGLCGN++G+  +D   
Sbjct: 1018 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1077

Query: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
              G  A +    GNSWQ  ++    C   +  + P  DS +   +     CG L D  GP
Sbjct: 1078 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1135

Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
            F  C   +        C+ D C   G    LC  ++T    CQ AG  V PWR    CP+
Sbjct: 1136 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1195

Query: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
            +CPP+S Y  C+  CP +C        C   C E C C+ GF LSG  C+P + CGC+H 
Sbjct: 1196 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1255

Query: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
             G+Y   G+ +Y  PGC  LC C+    + C+   C   E C    G  GC A G++TC 
Sbjct: 1256 -GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1314

Query: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
            ASGDPHY TFDG    FMGTC YVL + C +R     F V   N   G G + V+ +  V
Sbjct: 1315 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1374

Query: 1603 HVTVFDLSISLLR-GCKVMLNGHRVALPVWL 1632
             V  F L +   +    V  +G + A  +W+
Sbjct: 1375 QVANFTLRLEQRQWKVTVRADGEQGARGLWV 1405



 Score =  326 bits (836), Expect = 2e-88
 Identities = 220/739 (29%), Positives = 330/739 (44%), Gaps = 64/739 (8%)

Query: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
            +C    C   Q C  + G   C A    VC+  G+ HY +FDG  + +   C+  +V++C
Sbjct: 504  SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563

Query: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHR--VLINSKQVTLPA 2019
                 LP F + AK+E   G      +  V +  Y   V+L +G    VL+++++  LP 
Sbjct: 564  SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622

Query: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
                  + V  S   ++V +  G+ V +D +  L + +P  +  +VCG+CGN+N +  D+
Sbjct: 623  SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682

Query: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
             + P   +A    EF +SWK  D D  C+     +   PA    Q ++  G+     L +
Sbjct: 683  FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 740

Query: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
                    L  P +A C   +D  PFL  C   LC  GG   +LC+ L A+   C   G+
Sbjct: 741  --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 791

Query: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
                WR+ + CPL CPA S Y  C P+C  S       C GA  PS      C EGC+C 
Sbjct: 792  SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 844

Query: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
            PG+V S   CVP S CGC        P  + W    C  +C C G    + C D + CP+
Sbjct: 845  PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 904

Query: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
            G  C +   N    C  D+   C   GDP Y++FDG  +   G  TY+L+ +      LP
Sbjct: 905  GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 962

Query: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
                 +LVE  ++     S  + + V     G KV ++     +++V++    +P++  +
Sbjct: 963  --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 1018

Query: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
              ++V   G+   + TDF L V++         +PS Y   + GLCGN++ +  +D+ L 
Sbjct: 1019 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078

Query: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
             G    N   FGNSW+ +T            A E G   +L      Q+           
Sbjct: 1079 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1121

Query: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQ 2602
            S   C +LADP+GPF  CH  + P+     CV D C    P +   L C  L+ YA  CQ
Sbjct: 1122 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1178

Query: 2603 EAGAALAGWRDRTLCESPC 2621
             AGA +  WR   LC   C
Sbjct: 1179 AAGATVHPWRSEELCPLSC 1197



 Score =  150 bits (380), Expect = 1e-35
 Identities = 111/377 (29%), Positives = 161/377 (42%), Gaps = 50/377 (13%)

Query: 2301 CGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT 2360
            C   +C +G  CQ+      + CV++ +  C   GDP Y TFDG  Y + G  +Y +++ 
Sbjct: 505  CEGMQCAAGQRCQVVG--GKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL 562

Query: 2361 V---DVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLE--LVVNNQKM 2415
                D LP       VE +N+    R   ++  V    Y + V L  G    ++V+NQ+ 
Sbjct: 563  CSEDDTLPA----FSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRS 618

Query: 2416 AVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKN 2474
             +P   +E  LRV   G R  +   F LVV++       +SLP+ ++  V GLCGNY+ +
Sbjct: 619  RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 678

Query: 2475 RKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC 2534
              +D + P GAL  +   F +SW++   D L                E G +       C
Sbjct: 679  PADDFLTPDGALAPDAVEFASSWKLDDGDYL---------------CEDGCQNNCPA--C 721

Query: 2535 SPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQV 2593
            +P Q       + C +L    GPFA CH T+ P PF E CV DLC     R      C+ 
Sbjct: 722  TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLS---LCRG 778

Query: 2594 LSGYAILCQEAGAALAGWRDRTLCESPCLQN----------PCQNDG-----QCREQGAT 2638
            LS YA  C E G ++  WR    C   C  N          P   +G      C  +   
Sbjct: 779  LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 838

Query: 2639 FTCECEVGY--GGGLCM 2653
              C C  G+   GG C+
Sbjct: 839  EGCVCLPGFVASGGACV 855


>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score =  366 bits (940), Expect = e-100
 Identities = 337/1279 (26%), Positives = 511/1279 (39%), Gaps = 208/1279 (16%)

Query: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207
            +P      C  +G  HY TFDG  F F G C Y+ ++ CG + + F     +++E     
Sbjct: 73   NPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESA--- 129

Query: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267
               LS+V + +    + L KG   LV G  V LP   S GV +  S  + +++   GL +
Sbjct: 130  APTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQS-GVLIQQSSSYTKVEARLGLVL 187

Query: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
             W+ D  L + + + Y+ K CGLCG+++G      L L  +      E GN  + D D  
Sbjct: 188  MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSEL-LSHNTKLTPMEFGNLQKMD-DPT 245

Query: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386
            ++CQ    V  P  + S     +G G C  L+  HG  F  C+  V   S+ ++C  D+C
Sbjct: 246  EQCQ--DPVPEPPRNCS-----TGFGICEELL--HGQLFSGCVALVDVGSYLEACRQDLC 296

Query: 1387 GFQGLQHL--LCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
              +    L  +C  ++  +  C  AG   + WR P FCP  CP N +Y  C  PC DTC 
Sbjct: 297  FCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356

Query: 1445 SGFSGMFCSDRCVEACECNPGFVLSGLE---CIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501
            +      C D CV  C C  G VL  +    C+P S+C C++   +Y       Y   C 
Sbjct: 357  NQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGAT--YSTDCT 414

Query: 1502 ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFM 1561
              C C S  R  CQ   C                     TC+  G  H+ TFDG  +   
Sbjct: 415  N-CTC-SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVH 453

Query: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLS--ISLLRGCKV 1619
            G C+YVLT+PC S    S F V A     G     + +K+V +++  +   + +    +V
Sbjct: 454  GDCSYVLTKPCDS----SAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEV 509

Query: 1620 MLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVEV--TVPSSYGGQL 1676
             LN     LP+  A   VTI R S+  ++  T+ GLQ+       +++   +     GQ 
Sbjct: 510  FLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQT 567

Query: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGK-----PSSCQE 1731
            CGLCGN+N+   DD     R L+G      AA+     ++  C  +          S + 
Sbjct: 568  CGLCGNFNSIQADDF----RTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVEN 623

Query: 1732 NSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYAS 1791
               A  W   C+ L +  GPF +CH  V P + +++C+   C  +     LC +L +Y  
Sbjct: 624  EKYAQHW---CSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVH 680

Query: 1792 LCAQAG-QAPAWRNRTFC-PMR-CPPGSSYSPCSSPCPDTCSSINNPR-DCPKALPCAES 1847
             CA  G Q   WR+     PM  CP   +Y    S C  TC S++     C       + 
Sbjct: 681  ACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDG 740

Query: 1848 CECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTEN---TCTRL----------- 1892
            C C KG  L  T  CV    C C    GS  P GE  +      TCT             
Sbjct: 741  CICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPA 799

Query: 1893 -----------------------CTCSVHN-NITCFQSTCKPNQICWALDGLLRCRASG- 1927
                                   C  S H  ++TC+   C P  +C   DGL+     G 
Sbjct: 800  PVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVC--PDGLVADGEGGC 857

Query: 1928 ------------------------------------------VGVCQLPGESHYVSFDGS 1945
                                                      +  C + G+ HY++FDG 
Sbjct: 858  ITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQ 917

Query: 1946 NHSIPDACTLVLVKV-C--HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTL 2002
            ++S    C   LV+  C    +    F  ++        GT   +  ++++  ++ +++ 
Sbjct: 918  SYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSH 977

Query: 2003 QKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYY 2062
             K   +  +  Q       ++P  +++   IY +V+  IG+ + +D    + I +   + 
Sbjct: 978  GKVEVIGTDESQ-------EVP-YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFK 1029

Query: 2063 GKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQ 2122
            G+VCG+CGNF+D   ++    S  V     EF NSWK   + PSC   L           
Sbjct: 1030 GRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK---LSPSCPDALA---------- 1076

Query: 2123 ENPSGNCRAADLRR--AREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQ 2178
              P   C A   R+  A+++C + L  P +A C + ++   +   C N    C+ GG  +
Sbjct: 1077 --PKDPCTANPFRKSWAQKQC-SILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCE 1133

Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSCWDL 2231
              C A+ A+   C   GL    WR  S CPL C  Y+        Y  C   C  +C + 
Sbjct: 1134 CFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192

Query: 2232 DGRCEGAKVPSACAEGCI--CQP-GYVLSEDKCVPRSQCGCK------DAHGGSIPLGKS 2282
             G C          EGC   C P   +  EDK    + C           HG S   G  
Sbjct: 1193 RGDC---LRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAV 1249

Query: 2283 WVSSGCTEKCVCTGGAIQC 2301
              S    + C+CT   ++C
Sbjct: 1250 VPSDKNCQSCLCTERGVEC 1268



 Score =  310 bits (793), Expect = 2e-83
 Identities = 303/1200 (25%), Positives = 472/1200 (39%), Gaps = 203/1200 (16%)

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
            A     C+  G  HY TFDG +  F G C YV +  C +  +D    +  + E+    L 
Sbjct: 75   AHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS 134

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
               +K   V      I L +G  V++NGH V LP   +Q  V I+ SS+   +    GL 
Sbjct: 135  RVLMKVDGVV-----IQLTKG-SVLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLV 186

Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL-DDNLRPDRKLAGDSMQLGAAWKLPES 1714
            + ++    + + + + Y  + CGLCG++N   +  + L  + KL    M+ G   K+ + 
Sbjct: 187  LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDP 244

Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
            +E     V   P +C            C  L++ Q  FS C  +V   S   +C    C 
Sbjct: 245  TEQCQDPVPEPPRNCSTGFGI------CEELLHGQ-LFSGCVALVDVGSYLEACRQDLCF 297

Query: 1775 TKGDTTAL---CRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
             + DT  L   C +L  Y+  C  AG  P  WR   FCP +CP    Y  C SPC DTCS
Sbjct: 298  CE-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356

Query: 1831 SINNPRDCPKALPCAESCECQKGHILSG---TSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
            +  + R C     C   C C +G +L     T CVP+ +C C     +Y P G  + T+ 
Sbjct: 357  NQEHSRACEDH--CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP-GATYSTD- 412

Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947
             CT  CTCS     +C +  C                    G C + G +H+ +FDG  +
Sbjct: 413  -CTN-CTCS-GGRWSCQEVPCP-------------------GTCSVLGGAHFSTFDGKQY 450

Query: 1948 SIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ--VTLQKG 2005
            ++   C+ VL K C  +     F + A+  +         L  V + +   Q  V ++  
Sbjct: 451  TVHGDCSYVLTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506

Query: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEI--EIPTTYYG 2063
              V +N     LP IS       + S+ + I    +G+Q+       +++  ++     G
Sbjct: 507  GEVFLNQIYTQLP-ISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565

Query: 2064 KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQE 2123
            + CG+CGNFN  + D+    S  V  + + F N++K +   P+ ++   D   +  E ++
Sbjct: 566  QTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEK 625

Query: 2124 NPSGNC-RAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQ 2182
                 C +  D      +C AA++   +              +C    C        LC 
Sbjct: 626  YAQHWCSQLTDADGPFGRCHAAVKPGTYYS------------NCMFDTCNCERSEDCLCA 673

Query: 2183 ALQAFGATCQSQGLKPPLWRNSSFCP--LECPAYSSYTNCLPSCSPSCWDL---DGRCEG 2237
            AL ++   C ++G++   WR+         CP   +Y   + +C P+C  L   D  C  
Sbjct: 674  ALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSV 733

Query: 2238 AKVPSACAEGCICQPGYVLSED-KCVPRSQCGC----------KDAH------------- 2273
              +P    +GCIC  G  L +  KCV  S C C          +  H             
Sbjct: 734  GFIP---VDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKL 790

Query: 2274 ---GGSIP-------------------------------LGKSWVSSGCTEKCVCTGGAI 2299
               GG  P                               L  +  S  C   CVC  G +
Sbjct: 791  SCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLV 850

Query: 2300 QCGDFRCPSGSHCQL--------------------TSDNSNSNCVSDKS-EQCSVYGDPR 2338
              G+  C +   C                      T D+    C  D     C+VYGD  
Sbjct: 851  ADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGH 910

Query: 2339 YLTFDGFSYRLQGRMTYVLIKT-VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYG 2397
            YLTFDG SY   G   Y L++          +   V   N       +   + +   + G
Sbjct: 911  YLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGG 970

Query: 2398 YKVQLQAG-LELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV--TDFELVVSFGGRKNAVI 2454
            ++++L  G +E++  ++   VPY        T+    +YLV  TD  LV+ +  + +  I
Sbjct: 971  FELKLSHGKVEVIGTDESQEVPY--------TIRQMGIYLVVDTDIGLVLLWDKKTSIFI 1022

Query: 2455 SLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPA 2514
            +L   ++G V GLCGN+D    ND    S ++  ++  FGNSW++         P A+  
Sbjct: 1023 NLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS-----CPDALAP 1077

Query: 2515 EEEGQGAELGLRTGLQVSECSPEQLASNSTQ-ACRVLADPQGPFAACHQTVAPEPFQEHC 2573
            ++                 C+      +  Q  C +L  P   FAACH  V P  + E C
Sbjct: 1078 KD----------------PCTANPFRKSWAQKQCSILHGP--TFAACHAHVEPARYYEAC 1119

Query: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC-LQNPCQNDGQC 2632
            V D C A D     E  C  ++ YA  C E G  ++ WR  ++C   C   NP   +GQC
Sbjct: 1120 VNDAC-ACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNP---EGQC 1174



 Score =  180 bits (457), Expect = 1e-44
 Identities = 140/492 (28%), Positives = 207/492 (42%), Gaps = 54/492 (10%)

Query: 1042 ERCPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFLFSD---NHCIQASSCN 1094
            ++CP N +Y  C  P +  C +   S  C   C  GC C  G +  D     C+  S C 
Sbjct: 336  QKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA 395

Query: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154
            C YN   Y PGA  +S +CT +C C  G R  CQ   C                      
Sbjct: 396  CVYNGAAYAPGAT-YSTDCT-NCTC-SGGRWSCQEVPC--------------------PG 432

Query: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLSK 1213
            TC V G  H+ TFDG+ +   G C+Y+L +PC +S    F V A+    G  +  +CL  
Sbjct: 433  TCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA---FTVLAELRRCGLTDSETCLKS 489

Query: 1214 VYVTLP-ESTVTLLKGRRTLVGGQQVT-LPAIPSKGVFLGASGRFVELQTEFGLRVRWD- 1270
            V ++L    TV ++K    +   Q  T LP   +       S  F+  QT  GL++    
Sbjct: 490  VTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQL 549

Query: 1271 -GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQE 1329
                QL++ ++    G+ CGLCGN++    +D   L G          N+++T       
Sbjct: 550  VPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT----QAA 605

Query: 1330 CQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
            C   +      C  S+++      +C +L D  GPF  C   VK  +++ +CM D C  +
Sbjct: 606  CPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCE 665

Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC--PM-ACPPNSKYSLCAKPCPDTCHSG 1446
              +  LC  +S+    C   G  +  WR+   C  PM  CP +  Y      C  TC S 
Sbjct: 666  RSEDCLCAALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVSTCQPTCRSL 724

Query: 1447 FSG-MFCSDRC--VEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502
              G + CS     V+ C C  G  L    +C+  S C C H  GS    GE  +  G   
Sbjct: 725  SEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGA-- 781

Query: 1503 LCVCESNNRIRC 1514
            +C C ++ ++ C
Sbjct: 782  ICTC-THGKLSC 792



 Score =  170 bits (431), Expect = 2e-41
 Identities = 149/530 (28%), Positives = 211/530 (39%), Gaps = 85/530 (16%)

Query: 1055 CPASCKSPRPSC-GPLCREGCVCNPGFLFS-DNHCIQASSCNCFYNNDYYEPGAEWFSPN 1112
            C  SC +   +C  P C  GCVC  G +   +  CI A  C C +N   Y  G       
Sbjct: 823  CQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT----- 877

Query: 1113 CTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHF 1172
                       RV C    C +          + C      ATC VYGD HY+TFDG+ +
Sbjct: 878  ----------IRVGCNTCTCDSR--------MWRCTDDPCLATCAVYGDGHYLTFDGQSY 919

Query: 1173 GFMGKCTYILAQP-CG--NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR 1229
             F G C Y L Q  CG  +ST   FRV  +N   G  G +C   + + L    + L  G+
Sbjct: 920  SFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGK 979

Query: 1230 RTLVG---GQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGK 1286
              ++G    Q+V    I   G++L        + T+ GL + WD    +++ +S  + G+
Sbjct: 980  VEVIGTDESQEVPY-TIRQMGIYL-------VVDTDIGLVLLWDKKTSIFINLSPEFKGR 1031

Query: 1287 LCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQ 1346
            +CGLCGN+D  + ND      S  GD  E GNSW+        C        P   +  +
Sbjct: 1032 VCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL----SPSCPDALAPKDPCTANPFR 1087

Query: 1347 SSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMT 1403
             S +    C  L   HGP F  C  HV+ A ++++C+ D C     G     CT ++   
Sbjct: 1088 KSWAQKQ-CSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYA 1143

Query: 1404 TTCQDAGHAVKPWREPHFCPMACP---PNSK----YSLCAKPCPDTCHSGFSGMFCSDRC 1456
              C + G  V  WR P  CP+ C    P  +    Y  C  PC  TC +           
Sbjct: 1144 QACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWG 1202

Query: 1457 VEAC--ECNPG---FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNR 1511
            +E C  +C P    F    ++C+       L P      V  + Y+PG     V  S+  
Sbjct: 1203 LEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPR---CHVHGKSYRPG----AVVPSDK- 1254

Query: 1512 IRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTAS------GDPHYLTFDG 1555
              CQ   C        + G+   +   A  CT +      GD  Y T DG
Sbjct: 1255 -NCQSCLC-------TERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDG 1296



 Score = 52.0 bits (123), Expect = 8e-06
 Identities = 85/355 (23%), Positives = 125/355 (35%), Gaps = 39/355 (10%)

Query: 620  TIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPT 679
            T+ + +PT     PT    + T  +  P+ STE+PT  +    T T  T  +   PV   
Sbjct: 1686 TVATTRPT---PHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRN 1742

Query: 680  EKPSIPTEK---PSIPTEKPTISMEET----IISTEKPTISPEKPTIPTEKPTIPTEKST 732
              P     K      P+  P    +ET    I S EK    PE             E + 
Sbjct: 1743 CHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPE-------------EITR 1789

Query: 733  ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPT-IPT 791
            +     + P        +    S E+      +    P K+ +  E   +  E P   P 
Sbjct: 1790 LQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPV 1849

Query: 792  EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
                ++   P+TP+      T+  S      +     TTT V  +T ST + +      T
Sbjct: 1850 TSTPVTA--PSTPSGRAISPTQSTS------SWQKSRTTTLVTTSTTSTPQTSTTYAHTT 1901

Query: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
             +T  PT  T     +      P    + P   P+     +TIS    +I +   T +  
Sbjct: 1902 STTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS 1961

Query: 912  KPTIS-TEKPTIPTEKPTIPTEETTIS--TEKLTIPTEKPTISPEKLTIPTEKPT 963
             PT S T  PT  T   + PT  TT S  T   + PT   T  P   T P+  PT
Sbjct: 1962 APTSSTTSAPT--TSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG--TTPSPVPT 2012



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 52/178 (29%), Positives = 69/178 (38%), Gaps = 20/178 (11%)

Query: 531  PGTCPVKVLPELPP-------VSPVSSTG---PSETTGLTENPTISTKKPTVSIEKPSVT 580
            P  CPV   P   P       +SP  ST     S TT L    T ST + + +    + T
Sbjct: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903

Query: 581  TEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKP 640
            T  PT      + PT + T S    +  S   N PS  PT      TI     +I S   
Sbjct: 1904 TSAPTA--RTTSAPTTR-TTSASPASTTSGPGNTPSPVPT----TSTISAPTTSITSAPT 1956

Query: 641  TIPSEKPTISTEKPTVPTEEPTT-PTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697
            T  +  PT ST   + PT   T+ PT  TT+S +         S  +   + P+  PT
Sbjct: 1957 TSTTSAPTSST--TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPT 2012



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 47/167 (28%), Positives = 63/167 (37%), Gaps = 14/167 (8%)

Query: 608  PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE-PTTPTE 666
            P   P+ PS +   P++  +   +  T      +  S   T +T   T  T   PT  T 
Sbjct: 1853 PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTT 1912

Query: 667  ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPT-----IPT 721
               T+      P    S P   PS      TIS   T I++   T +   PT      PT
Sbjct: 1913 SAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPT 1972

Query: 722  EKPT-IPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPT 767
               T  PT  +T SP+  TT     + PT   T  P   TTP+  PT
Sbjct: 1973 TSTTSAPTSSTTSSPQTSTT-----SAPTTSTTSGP--GTTPSPVPT 2012



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 125/576 (21%), Positives = 205/576 (35%), Gaps = 93/576 (16%)

Query: 544  PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKP---TIPTEKPTI 600
            P++  +S+ P++TT  T + T  T+    S    +  T   +  +  P   T  + K T 
Sbjct: 1478 PLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTF 1537

Query: 601  STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
            ST  P             P +P+   + ++   T P    ++ S KPT++    +   +E
Sbjct: 1538 STPSP-------------PPVPATSTSSMST--TTPGT--SVVSSKPTLTEPSTSSCLQE 1580

Query: 661  PTTPTEETTTSMEEPVIP-----------------TEKP-SIPTEKPSIPTEKPTISMEE 702
              T TE    S   P I                   E P S+     S P        ++
Sbjct: 1581 LCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQD 1640

Query: 703  TIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP 762
             I S  +  I   K  +P   P     +  I   +        T P +  T++    T P
Sbjct: 1641 VICSHTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPK--TVAT---TRP 1692

Query: 763  TEKPTISPEKLTIPTEKPTIPTEKPTIPTEK-PTISTEEPTTPTEETTISTEKP------ 815
            T  PT +  + T  T  P+  TE+PT  +   PT ++    T T   T +          
Sbjct: 1693 TPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKW 1752

Query: 816  ---SIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKL- 871
                 P   P    +ET  ++     S EK+     +P   T         P +S E L 
Sbjct: 1753 FDVDFPSPGPHGGDKETYNNIIR---SGEKIC---RRPEEITRLQCRAKSHPEVSIEHLG 1806

Query: 872  ----TIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927
                    E L    +    P +   ++ E   +  E P   P   T  T  P+ P+ + 
Sbjct: 1807 QVVQCSREEGLVCRNQDQQGPFK-MCLNYEVRVLCCETPRGCPVTSTPVTA-PSTPSGRA 1864

Query: 928  TIPTEETTI--STEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985
              PT+ T+    +   T+ T   T +P+  T  T   T ST   + PT + T      + 
Sbjct: 1865 ISPTQSTSSWQKSRTTTLVTTSTTSTPQTST--TYAHTTSTT--SAPTARTT------SA 1914

Query: 986  PTEKPTIPTEKLTALRP---PHPSPTATGLAALVMS---------PHAPSTPMTSVILGT 1033
            PT + T  +   T   P   P P PT + ++A   S           AP++  TS    +
Sbjct: 1915 PTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTS 1974

Query: 1034 TTTSRSSTERCPPNARYESCACPASCKSPRPSCGPL 1069
            TT++ +S+    P     S    ++   P  +  P+
Sbjct: 1975 TTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPV 2010



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 62/204 (30%), Positives = 77/204 (37%), Gaps = 40/204 (19%)

Query: 544  PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE 603
            PV+    T PS  +G   +PT ST     S     VTT   + P+   T      T +T 
Sbjct: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA--HTTSTTS 1905

Query: 604  KPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIST-EKPTVPTEEPT 662
             PT  +   + P+ + T  S  P   T  P         PS  PT ST   PT  T   +
Sbjct: 1906 APT--ARTTSAPTTRTT--SASPASTTSGPG------NTPSPVPTTSTISAPT--TSITS 1953

Query: 663  TPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTE 722
             PT  TT             S PT   S  T  PT S   T   T   T SP+     T 
Sbjct: 1954 APTTSTT-------------SAPT---SSTTSAPTTST--TSAPTSSTTSSPQ-----TS 1990

Query: 723  KPTIPTEKSTISPEKPTTPTEKPT 746
              + PT  +T  P   TTP+  PT
Sbjct: 1991 TTSAPTTSTTSGP--GTTPSPVPT 2012


>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  324 bits (830), Expect = 8e-88
 Identities = 298/1197 (24%), Positives = 482/1197 (40%), Gaps = 185/1197 (15%)

Query: 1108 WFSPN------CTEHCRCWPGSRVECQISQCGTHTVCQL----KNGQYGCHPYAGTATCL 1157
            +FSP+      C     C      +CQI Q    T CQ+     NG+ G         C 
Sbjct: 15   FFSPSGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNGRDGI--------CK 65

Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV-SCLSKVYV 1216
             +G  H+ TFDG ++ F G C+YI A+ CG+  +P + V   N  +    V SC   + +
Sbjct: 66   TWGQYHFETFDGIYYYFPGNCSYIFAKDCGD-LEPRYTVWVHNSPKCLGSVYSCYRSISL 124

Query: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLY 1276
                     + G      G  +TLP    + +F+     ++ ++T FG  + WDG   +Y
Sbjct: 125  FFSNQEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIY 183

Query: 1277 VTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVV 1336
            + +S  + GK CGLCGNY+    +D + L      D     NSW     +D +C      
Sbjct: 184  LKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSD 243

Query: 1337 NSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLC 1396
                C S + +  +    C  L+    PF +C  ++    +  SC+ D+C         C
Sbjct: 244  FPNPCSSGMPAFEAIFFKCQILLQF--PFLSCHEYIDPYLYIASCVNDLCKTDD-DETYC 300

Query: 1397 THMSTMTTTCQDAGHAVKPWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455
               +     C  AG+ ++ WR+    C   C  +  +  C   CP TC      +  +  
Sbjct: 301  RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLH 360

Query: 1456 CVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCESNNRIRC 1514
            C++ C C  G V+    CI    C C  H  G  + VG +  +  C E CVC        
Sbjct: 361  CLDGCYCPDGLVMDNGTCISLENCPCGFH--GLAYSVGSK-IEQECTE-CVCVGG----- 411

Query: 1515 QPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWS 1574
              W C  Q+          C  Q    C+  GD H+ TFDG  + F+G C Y+L +    
Sbjct: 412  -VWNCTEQD----------CPVQ----CSVVGDSHFTTFDGRHYSFIGMCQYILVK---G 453

Query: 1575 RSQDSYFVV--SATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632
              +D + +    A  E   G++ +  I  +    F+  ++L RG +++ + ++     + 
Sbjct: 454  TGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG----FN 509

Query: 1633 AQGRVTIR-LSSNLVLLYTNFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLD 1689
              G V I+ LSS  +LL T FGL++ +  DG  +  + + S++  +  GLCG +N N  D
Sbjct: 510  LNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCGTFNGNIRD 568

Query: 1690 DNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP--SSCQENSMADAWNKNCAILIN 1747
            D L P   + G       AW++  +    CF     P    C  N     +  +C ++  
Sbjct: 569  DFLSPSGMIEGTPQLHANAWRVSST----CFAPVHVPVVDPCNINQQNIGYAAHCDVI-- 622

Query: 1748 PQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNR-T 1806
             Q  F+ CH  + P   +  C H  C  K  ++ LC +L  YA LC Q G    +R + +
Sbjct: 623  HQELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQIS 680

Query: 1807 FCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS--CVPL 1864
            FC + C  G  Y  CSS C  +C S+++P  C     CAE C C +G     T   CVP+
Sbjct: 681  FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPI 738

Query: 1865 GQCGCTDPAGSYHPVGERWYTENTCTRLCTCS---------------------------- 1896
              C C      Y P GE   T +    LC CS                            
Sbjct: 739  FHCRCHYRGSVYQP-GELIPTPSG---LCQCSNGTVKCDELATPSAVHICPEGKEYFDCR 794

Query: 1897 ----------VHNNITC----FQSTCKPNQICWA---------LDGLLRCRASGV-GVCQ 1932
                      V+   TC       TC P+  C +           G+  C       VC 
Sbjct: 795  FPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCT 854

Query: 1933 LPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVY 1992
            + G+ HY SFDG  +     C + L+K    +       + A+++K              
Sbjct: 855  IYGDRHYYSFDGLEYDYISDCQVFLIKSADDS----DISVIAQNKK-------------- 896

Query: 1993 IDIYDAQVTLQKGHRVLINSKQVTL---PAISQIPGVSVKSSSIYSIVNIKIGVQVKF-- 2047
               +D  +   K   + +   ++ L   P   +  G  +++ S Y +      + V F  
Sbjct: 897  --CFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPE 954

Query: 2048 -------DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
                   D    + I++   +  K+ G+CGNF+    +++   ++    +   F +SW  
Sbjct: 955  KDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-- 1012

Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
                  C+S   DE   P E  +N            A+++C + L + ++A C + ID+T
Sbjct: 1013 --ALGQCES--PDETIKPCEAHQN--------KFPYAKKEC-SILYSDIFASCRNVIDVT 1059

Query: 2161 PFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
             F  +C      C  GG  + LC ++ A+   C  +G+    WR+S+ C L+C  Y+
Sbjct: 1060 SFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYN 1115



 Score =  272 bits (696), Expect = 3e-72
 Identities = 271/1148 (23%), Positives = 448/1148 (39%), Gaps = 168/1148 (14%)

Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
            C   G  H+ TFDG  ++F G C+Y+  + C          V  + +  G +   S  ++
Sbjct: 64   CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY--SCYRS 121

Query: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
            + +   +     + G ++  NG  + LP  +  G++ I   ++ +L+ T FG  + +DG 
Sbjct: 122  ISLFFSNQEEIRIYGHEIKKNGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGI 179

Query: 1662 HLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFL 1721
              + + +   + G+ CGLCGNYN+   DD +        D      +W +    +  C L
Sbjct: 180  SGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVL 239

Query: 1722 VGGK-PSSCQENSMA-DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDT 1779
                 P+ C     A +A    C IL+  Q PF  CH+ + P    ASCV+  C T  D 
Sbjct: 240  TPSDFPNPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE 297

Query: 1780 TALCRSLQAYASLCAQAGQA-PAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRD 1837
            T  CR+   YA  C+ AG     WR+    C  +C     +  C S CP TC+     + 
Sbjct: 298  T-YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTF---EKQ 353

Query: 1838 CPKA-LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
            C  + L C + C C  G ++   +C+ L  C C     +Y  VG +   E  CT  C C 
Sbjct: 354  CLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYS-VGSK--IEQECTE-CVC- 408

Query: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLV 1956
            V     C +  C P Q                  C + G+SH+ +FDG ++S    C  +
Sbjct: 409  VGGVWNCTEQDC-PVQ------------------CSVVGDSHFTTFDGRHYSFIGMCQYI 449

Query: 1957 LVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYI---DIYDAQVTLQKGHRVLINSK 2013
            LVK          F I+ +    E       L  + +   D ++ QVTL +G ++L +  
Sbjct: 450  LVK----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPN 505

Query: 2014 Q-VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF--DGNHLLEIEIPTTYYGKVCGMCG 2070
            Q   L  I +I  +S    S++ ++    G+++ F  DG  +  I++ + +  +  G+CG
Sbjct: 506  QGFNLNGIVEIQTLS----SLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCG 560

Query: 2071 NFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCR 2130
             FN    D+ + PS  +  +     N+W+   +  +C + +      P    +   G   
Sbjct: 561  TFNGNIRDDFLSPSGMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNINQQNIGYAA 617

Query: 2131 AADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGAT 2190
              D+          +   ++A C   I    +   C +  C+ G     LC AL  +   
Sbjct: 618  HCDV----------IHQELFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665

Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
            C   G+        SFC + C     Y +C   C  SC  L       +    CAEGC C
Sbjct: 666  CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLS---SPEQCSDDCAEGCNC 722

Query: 2251 QPG--YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPS 2308
              G  Y  + + CVP   C C   + GS+      + +  +  C C+ G ++C +   PS
Sbjct: 723  PEGKFYEDTLNFCVPIFHCRCH--YRGSVYQPGELIPTP-SGLCQCSNGTVKCDELATPS 779

Query: 2309 GSH------------------------CQLTSDN--------SNSNCVS----------- 2325
              H                        C+ T  N         +S C+S           
Sbjct: 780  AVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRR 839

Query: 2326 --------DKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRN 2377
                         C++YGD  Y +FDG  Y         LIK+ D        + V  +N
Sbjct: 840  GMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSAD-----DSDISVIAQN 894

Query: 2378 KMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV 2437
            K       +  + V+ +V   ++ L          QK +  +  N+     LW    Y+V
Sbjct: 895  KKCFDNDIVCSKSVLISVGDTEIYLND----TPYKQKQSGFFLENKS-TYQLWKAGYYIV 949

Query: 2438 TDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG 2494
              F   ++ + +  +    I +   ++  +SGLCGN+DK   NDM   +    +N   FG
Sbjct: 950  VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009

Query: 2495 NSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQ-LASNSTQACRVLADP 2553
            +SW +   ++        P E               +  C   Q     + + C +L   
Sbjct: 1010 DSWALGQCES--------PDE--------------TIKPCEAHQNKFPYAKKECSILY-- 1045

Query: 2554 QGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRD 2613
               FA+C   +    F ++C  D C+     + E L C  ++ YA  C + G ++  WR 
Sbjct: 1046 SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL-CTSIAAYAYKCCQEGISI-HWRS 1103

Query: 2614 RTLCESPC 2621
             T+C   C
Sbjct: 1104 STVCSLDC 1111



 Score =  209 bits (532), Expect = 3e-53
 Identities = 208/848 (24%), Positives = 327/848 (38%), Gaps = 140/848 (16%)

Query: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPL--CREGCVCNPGFLFSDNHCIQASSCNCF 1096
            T++C  +  +  C   CP +C   +   G    C +GC C  G +  +  CI   +C C 
Sbjct: 328  TDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCG 387

Query: 1097 YNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATC 1156
            ++   Y  G++     CTE                      C    G + C        C
Sbjct: 388  FHGLAYSVGSK-IEQECTE----------------------CVCVGGVWNCTEQDCPVQC 424

Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYV 1216
             V GD H+ TFDGRH+ F+G C YIL +  G   D F     K   +   G+ CL  + +
Sbjct: 425  SVVGDSHFTTFDGRHYSFIGMCQYILVK--GTGKDKFTITLQKAPCEQNLGLVCLQSITL 482

Query: 1217 TLPE---STVTLLKGRRTLVGGQQVTLPAIPSKGVFLGA-------SGRFVELQTEFGLR 1266
             L +     VTL  GR    GGQ +T    P++G  L         S  F+ L+T FGL+
Sbjct: 483  ILEDDFNKQVTL--GR----GGQILT---SPNQGFNLNGIVEIQTLSSLFILLKTTFGLK 533

Query: 1267 VRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
            + +  D +++Y+ ++S +  +  GLCG ++GN  +D L   G   G  +   N+W+    
Sbjct: 534  ILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV--- 590

Query: 1326 EDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLD 1384
                C  +  V+ P  D     +    G+       H   F  C +++    ++  C  D
Sbjct: 591  -SSTC--FAPVHVPVVD-PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHD 646

Query: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
             C  +     LC  ++     C   G  +    +  FC + C     Y  C+  C  +C 
Sbjct: 647  AC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCI 704

Query: 1445 SGFSGMFCSDRCVEACECNPG-FVLSGLE-CIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502
            S  S   CSD C E C C  G F    L  C+P   C C H  GS ++ GE    P    
Sbjct: 705  SLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC-HYRGSVYQPGE--LIPTPSG 761

Query: 1503 LCVCESNNRIRCQPWRC-RAQEFCGQQDGIYGCH-------AQGA------------ATC 1542
            LC C SN  ++C       A   C +    + C        A G              TC
Sbjct: 762  LCQC-SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTC 820

Query: 1543 TAS---------------------------------GDPHYLTFDGALHHFMGTCTYVLT 1569
            T S                                 GD HY +FDG  + ++  C   L 
Sbjct: 821  TPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLI 880

Query: 1570 RPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALP 1629
            +     + DS   V A N+ +    ++   K+V ++V D  I L          ++    
Sbjct: 881  K----SADDSDISVIAQNK-KCFDNDIVCSKSVLISVGDTEIYLND------TPYKQKQS 929

Query: 1630 VWLAQGRVTIRL---SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNN 1686
             +  + + T +L      +V+ +    + + +D    + + V   +  +L GLCGN++  
Sbjct: 930  GFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKC 989

Query: 1687 SLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILI 1746
            + +D    +     ++   G +W L +   P   +   KP    +N    A  K C+IL 
Sbjct: 990  TSNDMTTSNNLEVRNARVFGDSWALGQCESPDETI---KPCEAHQNKFPYA-KKECSILY 1045

Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRN 1804
            +    F+ C  V+   S   +C    C     GD   LC S+ AYA  C Q G +  WR+
Sbjct: 1046 S--DIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRS 1103

Query: 1805 RTFCPMRC 1812
             T C + C
Sbjct: 1104 STVCSLDC 1111



 Score =  180 bits (456), Expect = 2e-44
 Identities = 163/706 (23%), Positives = 274/706 (38%), Gaps = 94/706 (13%)

Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988
            G+C+  G+ H+ +FDG  +  P  C+ +  K C      P + +   +  +  G+     
Sbjct: 62   GICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCY 119

Query: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048
              + +   + +     GH +  N   +TLP    I  + ++  + Y +V    G  + +D
Sbjct: 120  RSISLFFSNQEEIRIYGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWD 177

Query: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQ 2108
            G   + +++   + GK CG+CGN+ND + D+ ++  ++     + F NSW  +   P   
Sbjct: 178  GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQ--TPDDT 235

Query: 2109 SLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN 2168
              ++     P     NP  +   A       KC+  L+ P +  C   ID   ++  C N
Sbjct: 236  KCVLTPSDFP-----NPCSSGMPA-FEAIFFKCQILLQFP-FLSCHEYIDPYLYIASCVN 288

Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYSSYTNCLPSCSPS 2227
             LC+     +  C+A   +   C   G     WR+    C  +C     + +C+  C P+
Sbjct: 289  DLCKTDD-DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPT 347

Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
            C   + +C G+ +   C +GC C  G V+    C+    C C   HG +  +G S +   
Sbjct: 348  C-TFEKQCLGSNL--HCLDGCYCPDGLVMDNGTCISLENCPC-GFHGLAYSVG-SKIEQE 402

Query: 2288 CTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSY 2347
            CTE CVC GG   C +  CP                      QCSV GD  + TFDG  Y
Sbjct: 403  CTE-CVCVGGVWNCTEQDCP---------------------VQCSVVGDSHFTTFDGRHY 440

Query: 2348 RLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV----YGYKVQLQ 2403
               G   Y+L+K       G +   +  +         +   + IT +    +  +V L 
Sbjct: 441  SFIGMCQYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLG 495

Query: 2404 AGLELVVNNQKMAVPYRPNEHLRV-------TLWGQRLYLVTDFELVVSFG-GRKNAVIS 2455
             G +++ +         PN+   +       TL    + L T F L + F    +   I 
Sbjct: 496  RGGQILTS---------PNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQ 546

Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
            L S ++    GLCG ++ N ++D + PSG +        N+W V    +    P  +P  
Sbjct: 547  LTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV---SSTCFAPVHVPV- 602

Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVL 2575
                           V  C+  Q        C V+   Q  FA CH  ++P  + + C  
Sbjct: 603  ---------------VDPCNINQQNIGYAAHCDVI--HQELFAPCHIYISPGLYYQLCRH 645

Query: 2576 DLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            D C            C  L+ YA LC + G  +      + C   C
Sbjct: 646  DACKC-----GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC 686



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 99/441 (22%), Positives = 159/441 (36%), Gaps = 58/441 (13%)

Query: 1126 ECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP 1185
            + ++  CG        N    C  +     C +  +   +TFDG +       +YIL + 
Sbjct: 1411 DVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI 1470

Query: 1186 CGNSTDPFFRVTAKNEE-QGQEGVSCLSKVYVTLPESTVTLLK-GRRTLVGGQQVTLPAI 1243
             G          + N+   G+    C  K+ VT P   + + +  R+  V    V LP  
Sbjct: 1471 PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLP-F 1529

Query: 1244 PSKGVFLGASGRFVELQTEFGLRVRWD---GDQQLYVTVSSTYSGKLCGLCGNYDGNSDN 1300
             S+ + +  SG    + T  GL ++W    G   ++       S    GLCG  + + D+
Sbjct: 1530 SSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDD 1589

Query: 1301 DHLKLDGSPAGDKEELG---NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGR 1357
            D    +G+   + E++G    SW+ ++  +   ++  V N    D            C +
Sbjct: 1590 DLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRR-PVRNCTEHD------------CSQ 1636

Query: 1358 LVD--THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKP 1415
             +D      F  C   V    F +   ++   F   +   C  +S     C      ++ 
Sbjct: 1637 CIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692

Query: 1416 WREPHFCPMACPPNSKYSLCAKPC-PDTC-HSGFSGMFCSDRCVEACECNPGFVL---SG 1470
            WR P +C ++CP   +Y  C +PC   TC +  F G        E C C  G VL     
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHS 1752

Query: 1471 LECIPRSQCGCLHPAGSYFKVGERW---------YK-----------PGCKE--LCVCES 1508
             +CIP  +C C          GE W         YK           P C E    VCE 
Sbjct: 1753 AQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCER 1812

Query: 1509 NNRI---RCQPWRCRAQEFCG 1526
               +       W C ++E CG
Sbjct: 1813 EAEVVMGIIDKWTCCSKEVCG 1833



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 86/371 (23%), Positives = 145/371 (39%), Gaps = 47/371 (12%)

Query: 2285 SSGCTEKCV----CTG-GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
            S  C  +C+    C+  G   C  F+   G+ CQ+  +  N      +   C  +G   +
Sbjct: 19   SGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNG-----RDGICKTWGQYHF 72

Query: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIF-LQEVITTVYGY 2398
             TFDG  Y   G  +Y+  K    L    EP      +       S++     I+  +  
Sbjct: 73   ETFDGIYYYFPGNCSYIFAKDCGDL----EPRYTVWVHNSPKCLGSVYSCYRSISLFFSN 128

Query: 2399 KVQLQA-GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
            + +++  G E+  N   + +P    + + +      + + T F   +++ G     + L 
Sbjct: 129  QEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIYLKLS 187

Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTED--ALLRFPRAIPAE 2515
              ++G   GLCGNY+  + +D ++     T+++  F NSW V+T D    +  P   P  
Sbjct: 188  EDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFP-- 245

Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNST-QACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
                            + CS    A  +    C++L   Q PF +CH+ + P  +   CV
Sbjct: 246  ----------------NPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCV 287

Query: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDR-TLCESPCLQNPCQNDG-QC 2632
             DLC   D    +E  C+  + YA  C  AG  +  WRD    C   C  +    D   C
Sbjct: 288  NDLCKTDD----DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISC 343

Query: 2633 REQGATFTCEC 2643
                 TF  +C
Sbjct: 344  CPPTCTFEKQC 354



 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 99/427 (23%), Positives = 162/427 (37%), Gaps = 64/427 (14%)

Query: 1509 NNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL 1568
            N+ I C  W C  +                   C+   +   +TFDG         +Y+L
Sbjct: 1427 NSDICCPEWECPCR-------------------CSMLSELSIITFDGNNAALYSMASYIL 1467

Query: 1569 TRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL 1628
             R        ++    + N+   G +     K ++VT     I + R  +  +    + +
Sbjct: 1468 VR-IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR-KVEVDSIVV 1525

Query: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVP--------SSYGGQLCGLC 1680
            P+  +   ++I  S ++ ++ T  GL +++  SHL  +           SSY   LCG+C
Sbjct: 1526 PLPFSSQELSIEDSGSMYVITTPAGLIIKW--SHLTGIIDIHFGFRFNLSSYTEGLCGIC 1583

Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQ-LGA---AWKLPESSEPGCFLVGGKP-SSCQENSMA 1735
                N   DD+LR        +M+ +G    +W++ +S E    +   +P  +C E+  +
Sbjct: 1584 ----NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE----VTMRRPVRNCTEHDCS 1635

Query: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
                  C  L+N +  F  CH  V P+     C              C +L AY +LC +
Sbjct: 1636 Q-----CIDLLNRR-IFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNK 1686

Query: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPC-PDTCSS--INNPRDCPKALPCAESCECQK 1852
                  WR   +C + CP G  Y PC  PC   TC +        C   L   E C C+ 
Sbjct: 1687 FDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC---LNLREDCVCKV 1743

Query: 1853 GHIL---SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC- 1908
            G +L       C+P  +C CTD        GE W        L  C  + +I   +  C 
Sbjct: 1744 GTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCD 1803

Query: 1909 -KPNQIC 1914
             +P  +C
Sbjct: 1804 EEPTPVC 1810



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 115/557 (20%), Positives = 203/557 (36%), Gaps = 116/557 (20%)

Query: 1818 YSPCSSPCPDTCSSINNPRDCPKALPC-----AESC--ECQKGHILSGTS--------CV 1862
            Y PC++PC  TCS        P+AL C      E C   C K  IL   +        C+
Sbjct: 1281 YEPCATPCFKTCSD-------PEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCI 1333

Query: 1863 PLGQCGCT--DPAGSYHPVGERW--YTENTCTRLCTCSVHNNITCFQSTCKPNQIC---- 1914
            P+     T   PA    P+   W   T +  T     +    + C      P   C    
Sbjct: 1334 PVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYI 1393

Query: 1915 ----------WALD-----GLLRCRASGVGV----------------CQLPGESHYVSFD 1943
                      W+L+      +  C   G  V                C +  E   ++FD
Sbjct: 1394 CLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFD 1453

Query: 1944 GSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
            G+N ++    + +LV++    +     K S  ++   G        ++ +     ++ + 
Sbjct: 1454 GNNAALYSMASYILVRIPGEIIVAHIEKCSM-NQAPSGRISGLCFKKLNVTTPIHKIIVN 1512

Query: 2004 K-GHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG-NHLLEIEIP--- 2058
            +   +V ++S  V LP  SQ   +S++ S    ++    G+ +K+     +++I      
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQ--ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRF 1570

Query: 2059 --TTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE---FVNSWKDKDIDPSCQSLLVD 2113
              ++Y   +CG+C   N++ +D+L M +  +  +  +   F+ SW   +I+ S +  +  
Sbjct: 1571 NLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESW---EIEKSFEVTM-- 1622

Query: 2114 EQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEF 2173
                       P  NC   D      +C   L   ++  C  ++    F   C      +
Sbjct: 1623 ---------RRPVRNCTEHDC----SQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINY 1666

Query: 2174 GGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSC-SPSCWDLD 2232
               +   C AL A+ A C    +    WR   +C L CP    Y  C+  C + +C  L+
Sbjct: 1667 TYFWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTC--LN 1723

Query: 2233 GRCEGAKVPSACAEGCICQPGYVLSED---KCVPRSQCGCKDAHGGSIPLGKSWVSSGCT 2289
                G        E C+C+ G VL      +C+P  +C C D+       G+ W      
Sbjct: 1724 QWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIW------ 1777

Query: 2290 EKCVCTGGAIQCGDFRC 2306
                  GG  +C  ++C
Sbjct: 1778 -----NGGIDECTLYKC 1789



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 69/343 (20%), Positives = 127/343 (37%), Gaps = 60/343 (17%)

Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI--- 2386
            +CS+  +   +TFDG +  L    +Y+L++    +P  +    +E  +    P   I   
Sbjct: 1440 RCSMLSELSIITFDGNNAALYSMASYILVR----IPGEIIVAHIEKCSMNQAPSGRISGL 1495

Query: 2387 -FLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVS 2445
             F +  +TT     +  +   ++ V++  + +P+   E L +   G    + T   L++ 
Sbjct: 1496 CFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-LSIEDSGSMYVITTPAGLIIK 1554

Query: 2446 FG---GRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG---NSWEV 2499
            +    G  +              GLCG  +++  +D+ + +G +  N+   G    SWE+
Sbjct: 1555 WSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614

Query: 2500 -KTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFA 2558
             K+ +  +R P                     V  C+      +    C  L + +  F 
Sbjct: 1615 EKSFEVTMRRP---------------------VRNCT-----EHDCSQCIDLLN-RRIFI 1647

Query: 2559 ACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCE 2618
             CH  V+PE F E   ++     +        C  LS Y  LC +    +  WR    C 
Sbjct: 1648 PCHDKVSPEDFCEKMWINYTYFWN------YECDALSAYVALCNKFDICIQ-WRTPDYCS 1700

Query: 2619 SPCLQ----NPCQNDGQCREQGATFTCECEVGYGGGLCMEPRD 2657
              C +     PC    + R      TC  +  YG   C+  R+
Sbjct: 1701 LSCPEGKEYQPCVRPCEAR------TCLNQWFYGHTSCLNLRE 1737


>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  324 bits (830), Expect = 8e-88
 Identities = 298/1197 (24%), Positives = 482/1197 (40%), Gaps = 185/1197 (15%)

Query: 1108 WFSPN------CTEHCRCWPGSRVECQISQCGTHTVCQL----KNGQYGCHPYAGTATCL 1157
            +FSP+      C     C      +CQI Q    T CQ+     NG+ G         C 
Sbjct: 15   FFSPSGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNGRDGI--------CK 65

Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV-SCLSKVYV 1216
             +G  H+ TFDG ++ F G C+YI A+ CG+  +P + V   N  +    V SC   + +
Sbjct: 66   TWGQYHFETFDGIYYYFPGNCSYIFAKDCGD-LEPRYTVWVHNSPKCLGSVYSCYRSISL 124

Query: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLY 1276
                     + G      G  +TLP    + +F+     ++ ++T FG  + WDG   +Y
Sbjct: 125  FFSNQEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIY 183

Query: 1277 VTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVV 1336
            + +S  + GK CGLCGNY+    +D + L      D     NSW     +D +C      
Sbjct: 184  LKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSD 243

Query: 1337 NSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLC 1396
                C S + +  +    C  L+    PF +C  ++    +  SC+ D+C         C
Sbjct: 244  FPNPCSSGMPAFEAIFFKCQILLQF--PFLSCHEYIDPYLYIASCVNDLCKTDD-DETYC 300

Query: 1397 THMSTMTTTCQDAGHAVKPWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455
               +     C  AG+ ++ WR+    C   C  +  +  C   CP TC      +  +  
Sbjct: 301  RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLH 360

Query: 1456 CVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCESNNRIRC 1514
            C++ C C  G V+    CI    C C  H  G  + VG +  +  C E CVC        
Sbjct: 361  CLDGCYCPDGLVMDNGTCISLENCPCGFH--GLAYSVGSK-IEQECTE-CVCVGG----- 411

Query: 1515 QPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWS 1574
              W C  Q+          C  Q    C+  GD H+ TFDG  + F+G C Y+L +    
Sbjct: 412  -VWNCTEQD----------CPVQ----CSVVGDSHFTTFDGRHYSFIGMCQYILVK---G 453

Query: 1575 RSQDSYFVV--SATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632
              +D + +    A  E   G++ +  I  +    F+  ++L RG +++ + ++     + 
Sbjct: 454  TGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG----FN 509

Query: 1633 AQGRVTIR-LSSNLVLLYTNFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLD 1689
              G V I+ LSS  +LL T FGL++ +  DG  +  + + S++  +  GLCG +N N  D
Sbjct: 510  LNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCGTFNGNIRD 568

Query: 1690 DNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP--SSCQENSMADAWNKNCAILIN 1747
            D L P   + G       AW++  +    CF     P    C  N     +  +C ++  
Sbjct: 569  DFLSPSGMIEGTPQLHANAWRVSST----CFAPVHVPVVDPCNINQQNIGYAAHCDVI-- 622

Query: 1748 PQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNR-T 1806
             Q  F+ CH  + P   +  C H  C  K  ++ LC +L  YA LC Q G    +R + +
Sbjct: 623  HQELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQIS 680

Query: 1807 FCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS--CVPL 1864
            FC + C  G  Y  CSS C  +C S+++P  C     CAE C C +G     T   CVP+
Sbjct: 681  FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPI 738

Query: 1865 GQCGCTDPAGSYHPVGERWYTENTCTRLCTCS---------------------------- 1896
              C C      Y P GE   T +    LC CS                            
Sbjct: 739  FHCRCHYRGSVYQP-GELIPTPSG---LCQCSNGTVKCDELATPSAVHICPEGKEYFDCR 794

Query: 1897 ----------VHNNITC----FQSTCKPNQICWA---------LDGLLRCRASGV-GVCQ 1932
                      V+   TC       TC P+  C +           G+  C       VC 
Sbjct: 795  FPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCT 854

Query: 1933 LPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVY 1992
            + G+ HY SFDG  +     C + L+K    +       + A+++K              
Sbjct: 855  IYGDRHYYSFDGLEYDYISDCQVFLIKSADDS----DISVIAQNKK-------------- 896

Query: 1993 IDIYDAQVTLQKGHRVLINSKQVTL---PAISQIPGVSVKSSSIYSIVNIKIGVQVKF-- 2047
               +D  +   K   + +   ++ L   P   +  G  +++ S Y +      + V F  
Sbjct: 897  --CFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPE 954

Query: 2048 -------DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
                   D    + I++   +  K+ G+CGNF+    +++   ++    +   F +SW  
Sbjct: 955  KDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-- 1012

Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
                  C+S   DE   P E  +N            A+++C + L + ++A C + ID+T
Sbjct: 1013 --ALGQCES--PDETIKPCEAHQN--------KFPYAKKEC-SILYSDIFASCRNVIDVT 1059

Query: 2161 PFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
             F  +C      C  GG  + LC ++ A+   C  +G+    WR+S+ C L+C  Y+
Sbjct: 1060 SFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYN 1115



 Score =  272 bits (696), Expect = 3e-72
 Identities = 271/1148 (23%), Positives = 448/1148 (39%), Gaps = 168/1148 (14%)

Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
            C   G  H+ TFDG  ++F G C+Y+  + C          V  + +  G +   S  ++
Sbjct: 64   CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY--SCYRS 121

Query: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
            + +   +     + G ++  NG  + LP  +  G++ I   ++ +L+ T FG  + +DG 
Sbjct: 122  ISLFFSNQEEIRIYGHEIKKNGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGI 179

Query: 1662 HLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFL 1721
              + + +   + G+ CGLCGNYN+   DD +        D      +W +    +  C L
Sbjct: 180  SGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVL 239

Query: 1722 VGGK-PSSCQENSMA-DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDT 1779
                 P+ C     A +A    C IL+  Q PF  CH+ + P    ASCV+  C T  D 
Sbjct: 240  TPSDFPNPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE 297

Query: 1780 TALCRSLQAYASLCAQAGQA-PAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRD 1837
            T  CR+   YA  C+ AG     WR+    C  +C     +  C S CP TC+     + 
Sbjct: 298  T-YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTF---EKQ 353

Query: 1838 CPKA-LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
            C  + L C + C C  G ++   +C+ L  C C     +Y  VG +   E  CT  C C 
Sbjct: 354  CLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYS-VGSK--IEQECTE-CVC- 408

Query: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLV 1956
            V     C +  C P Q                  C + G+SH+ +FDG ++S    C  +
Sbjct: 409  VGGVWNCTEQDC-PVQ------------------CSVVGDSHFTTFDGRHYSFIGMCQYI 449

Query: 1957 LVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYI---DIYDAQVTLQKGHRVLINSK 2013
            LVK          F I+ +    E       L  + +   D ++ QVTL +G ++L +  
Sbjct: 450  LVK----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPN 505

Query: 2014 Q-VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF--DGNHLLEIEIPTTYYGKVCGMCG 2070
            Q   L  I +I  +S    S++ ++    G+++ F  DG  +  I++ + +  +  G+CG
Sbjct: 506  QGFNLNGIVEIQTLS----SLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCG 560

Query: 2071 NFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCR 2130
             FN    D+ + PS  +  +     N+W+   +  +C + +      P    +   G   
Sbjct: 561  TFNGNIRDDFLSPSGMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNINQQNIGYAA 617

Query: 2131 AADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGAT 2190
              D+          +   ++A C   I    +   C +  C+ G     LC AL  +   
Sbjct: 618  HCDV----------IHQELFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665

Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
            C   G+        SFC + C     Y +C   C  SC  L       +    CAEGC C
Sbjct: 666  CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLS---SPEQCSDDCAEGCNC 722

Query: 2251 QPG--YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPS 2308
              G  Y  + + CVP   C C   + GS+      + +  +  C C+ G ++C +   PS
Sbjct: 723  PEGKFYEDTLNFCVPIFHCRCH--YRGSVYQPGELIPTP-SGLCQCSNGTVKCDELATPS 779

Query: 2309 GSH------------------------CQLTSDN--------SNSNCVS----------- 2325
              H                        C+ T  N         +S C+S           
Sbjct: 780  AVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRR 839

Query: 2326 --------DKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRN 2377
                         C++YGD  Y +FDG  Y         LIK+ D        + V  +N
Sbjct: 840  GMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSAD-----DSDISVIAQN 894

Query: 2378 KMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV 2437
            K       +  + V+ +V   ++ L          QK +  +  N+     LW    Y+V
Sbjct: 895  KKCFDNDIVCSKSVLISVGDTEIYLND----TPYKQKQSGFFLENKS-TYQLWKAGYYIV 949

Query: 2438 TDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG 2494
              F   ++ + +  +    I +   ++  +SGLCGN+DK   NDM   +    +N   FG
Sbjct: 950  VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009

Query: 2495 NSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQ-LASNSTQACRVLADP 2553
            +SW +   ++        P E               +  C   Q     + + C +L   
Sbjct: 1010 DSWALGQCES--------PDE--------------TIKPCEAHQNKFPYAKKECSILY-- 1045

Query: 2554 QGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRD 2613
               FA+C   +    F ++C  D C+     + E L C  ++ YA  C + G ++  WR 
Sbjct: 1046 SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL-CTSIAAYAYKCCQEGISI-HWRS 1103

Query: 2614 RTLCESPC 2621
             T+C   C
Sbjct: 1104 STVCSLDC 1111



 Score =  209 bits (532), Expect = 3e-53
 Identities = 208/848 (24%), Positives = 327/848 (38%), Gaps = 140/848 (16%)

Query: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPL--CREGCVCNPGFLFSDNHCIQASSCNCF 1096
            T++C  +  +  C   CP +C   +   G    C +GC C  G +  +  CI   +C C 
Sbjct: 328  TDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCG 387

Query: 1097 YNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATC 1156
            ++   Y  G++     CTE                      C    G + C        C
Sbjct: 388  FHGLAYSVGSK-IEQECTE----------------------CVCVGGVWNCTEQDCPVQC 424

Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYV 1216
             V GD H+ TFDGRH+ F+G C YIL +  G   D F     K   +   G+ CL  + +
Sbjct: 425  SVVGDSHFTTFDGRHYSFIGMCQYILVK--GTGKDKFTITLQKAPCEQNLGLVCLQSITL 482

Query: 1217 TLPE---STVTLLKGRRTLVGGQQVTLPAIPSKGVFLGA-------SGRFVELQTEFGLR 1266
             L +     VTL  GR    GGQ +T    P++G  L         S  F+ L+T FGL+
Sbjct: 483  ILEDDFNKQVTL--GR----GGQILT---SPNQGFNLNGIVEIQTLSSLFILLKTTFGLK 533

Query: 1267 VRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
            + +  D +++Y+ ++S +  +  GLCG ++GN  +D L   G   G  +   N+W+    
Sbjct: 534  ILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV--- 590

Query: 1326 EDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLD 1384
                C  +  V+ P  D     +    G+       H   F  C +++    ++  C  D
Sbjct: 591  -SSTC--FAPVHVPVVD-PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHD 646

Query: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
             C  +     LC  ++     C   G  +    +  FC + C     Y  C+  C  +C 
Sbjct: 647  AC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCI 704

Query: 1445 SGFSGMFCSDRCVEACECNPG-FVLSGLE-CIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502
            S  S   CSD C E C C  G F    L  C+P   C C H  GS ++ GE    P    
Sbjct: 705  SLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC-HYRGSVYQPGE--LIPTPSG 761

Query: 1503 LCVCESNNRIRCQPWRC-RAQEFCGQQDGIYGCH-------AQGA------------ATC 1542
            LC C SN  ++C       A   C +    + C        A G              TC
Sbjct: 762  LCQC-SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTC 820

Query: 1543 TAS---------------------------------GDPHYLTFDGALHHFMGTCTYVLT 1569
            T S                                 GD HY +FDG  + ++  C   L 
Sbjct: 821  TPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLI 880

Query: 1570 RPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALP 1629
            +     + DS   V A N+ +    ++   K+V ++V D  I L          ++    
Sbjct: 881  K----SADDSDISVIAQNK-KCFDNDIVCSKSVLISVGDTEIYLND------TPYKQKQS 929

Query: 1630 VWLAQGRVTIRL---SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNN 1686
             +  + + T +L      +V+ +    + + +D    + + V   +  +L GLCGN++  
Sbjct: 930  GFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKC 989

Query: 1687 SLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILI 1746
            + +D    +     ++   G +W L +   P   +   KP    +N    A  K C+IL 
Sbjct: 990  TSNDMTTSNNLEVRNARVFGDSWALGQCESPDETI---KPCEAHQNKFPYA-KKECSILY 1045

Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRN 1804
            +    F+ C  V+   S   +C    C     GD   LC S+ AYA  C Q G +  WR+
Sbjct: 1046 S--DIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRS 1103

Query: 1805 RTFCPMRC 1812
             T C + C
Sbjct: 1104 STVCSLDC 1111



 Score =  180 bits (456), Expect = 2e-44
 Identities = 163/706 (23%), Positives = 274/706 (38%), Gaps = 94/706 (13%)

Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988
            G+C+  G+ H+ +FDG  +  P  C+ +  K C      P + +   +  +  G+     
Sbjct: 62   GICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCY 119

Query: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048
              + +   + +     GH +  N   +TLP    I  + ++  + Y +V    G  + +D
Sbjct: 120  RSISLFFSNQEEIRIYGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWD 177

Query: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQ 2108
            G   + +++   + GK CG+CGN+ND + D+ ++  ++     + F NSW  +   P   
Sbjct: 178  GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQ--TPDDT 235

Query: 2109 SLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN 2168
              ++     P     NP  +   A       KC+  L+ P +  C   ID   ++  C N
Sbjct: 236  KCVLTPSDFP-----NPCSSGMPA-FEAIFFKCQILLQFP-FLSCHEYIDPYLYIASCVN 288

Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYSSYTNCLPSCSPS 2227
             LC+     +  C+A   +   C   G     WR+    C  +C     + +C+  C P+
Sbjct: 289  DLCKTDD-DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPT 347

Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
            C   + +C G+ +   C +GC C  G V+    C+    C C   HG +  +G S +   
Sbjct: 348  C-TFEKQCLGSNL--HCLDGCYCPDGLVMDNGTCISLENCPC-GFHGLAYSVG-SKIEQE 402

Query: 2288 CTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSY 2347
            CTE CVC GG   C +  CP                      QCSV GD  + TFDG  Y
Sbjct: 403  CTE-CVCVGGVWNCTEQDCP---------------------VQCSVVGDSHFTTFDGRHY 440

Query: 2348 RLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV----YGYKVQLQ 2403
               G   Y+L+K       G +   +  +         +   + IT +    +  +V L 
Sbjct: 441  SFIGMCQYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLG 495

Query: 2404 AGLELVVNNQKMAVPYRPNEHLRV-------TLWGQRLYLVTDFELVVSFG-GRKNAVIS 2455
             G +++ +         PN+   +       TL    + L T F L + F    +   I 
Sbjct: 496  RGGQILTS---------PNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQ 546

Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
            L S ++    GLCG ++ N ++D + PSG +        N+W V    +    P  +P  
Sbjct: 547  LTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV---SSTCFAPVHVPV- 602

Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVL 2575
                           V  C+  Q        C V+   Q  FA CH  ++P  + + C  
Sbjct: 603  ---------------VDPCNINQQNIGYAAHCDVI--HQELFAPCHIYISPGLYYQLCRH 645

Query: 2576 DLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            D C            C  L+ YA LC + G  +      + C   C
Sbjct: 646  DACKC-----GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC 686



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 86/371 (23%), Positives = 145/371 (39%), Gaps = 47/371 (12%)

Query: 2285 SSGCTEKCV----CTG-GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
            S  C  +C+    C+  G   C  F+   G+ CQ+  +  N      +   C  +G   +
Sbjct: 19   SGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNG-----RDGICKTWGQYHF 72

Query: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIF-LQEVITTVYGY 2398
             TFDG  Y   G  +Y+  K    L    EP      +       S++     I+  +  
Sbjct: 73   ETFDGIYYYFPGNCSYIFAKDCGDL----EPRYTVWVHNSPKCLGSVYSCYRSISLFFSN 128

Query: 2399 KVQLQA-GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
            + +++  G E+  N   + +P    + + +      + + T F   +++ G     + L 
Sbjct: 129  QEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIYLKLS 187

Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTED--ALLRFPRAIPAE 2515
              ++G   GLCGNY+  + +D ++     T+++  F NSW V+T D    +  P   P  
Sbjct: 188  EDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFP-- 245

Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNST-QACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
                            + CS    A  +    C++L   Q PF +CH+ + P  +   CV
Sbjct: 246  ----------------NPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCV 287

Query: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDR-TLCESPCLQNPCQNDG-QC 2632
             DLC   D    +E  C+  + YA  C  AG  +  WRD    C   C  +    D   C
Sbjct: 288  NDLCKTDD----DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISC 343

Query: 2633 REQGATFTCEC 2643
                 TF  +C
Sbjct: 344  CPPTCTFEKQC 354



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 98/441 (22%), Positives = 159/441 (36%), Gaps = 58/441 (13%)

Query: 1126 ECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP 1185
            + ++  CG        N    C  +     C +  +   +TFDG +       +YIL + 
Sbjct: 1411 DVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI 1470

Query: 1186 CGNSTDPFFRVTAKNEE-QGQEGVSCLSKVYVTLPESTVTLLK-GRRTLVGGQQVTLPAI 1243
             G          + N+   G+    C  K+ VT P   + + +  R+  V    V LP  
Sbjct: 1471 PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLP-F 1529

Query: 1244 PSKGVFLGASGRFVELQTEFGLRVRWD---GDQQLYVTVSSTYSGKLCGLCGNYDGNSDN 1300
             S+ + +  SG    + T  GL ++W    G   ++       S    GLCG  + + D+
Sbjct: 1530 SSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDD 1589

Query: 1301 DHLKLDGSPAGDKEELG---NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGR 1357
            D    +G+   + E++G    SW+ ++  +   ++  V N    D            C +
Sbjct: 1590 DLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRR-PVRNCTEHD------------CSQ 1636

Query: 1358 LVD--THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKP 1415
             +D      F  C   V    F +   ++   F   +   C  +S     C      ++ 
Sbjct: 1637 CIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692

Query: 1416 WREPHFCPMACPPNSKYSLCAKPC-PDTC-HSGFSGMFCSDRCVEACECNPGFVL---SG 1470
            WR P +C ++CP   +Y  C +PC   TC +  F G        E C C  G +L     
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHS 1752

Query: 1471 LECIPRSQCGCLHPAGSYFKVGERW---------YK-----------PGCKE--LCVCES 1508
             +CIP  +C C          GE W         YK           P C E    VCE 
Sbjct: 1753 AQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCER 1812

Query: 1509 NNRI---RCQPWRCRAQEFCG 1526
               +       W C ++E CG
Sbjct: 1813 EAEVVMGIIDKWTCCSKEVCG 1833



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 100/427 (23%), Positives = 162/427 (37%), Gaps = 64/427 (14%)

Query: 1509 NNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL 1568
            N+ I C  W C  +                   C+   +   +TFDG         +Y+L
Sbjct: 1427 NSDICCPEWECPCR-------------------CSMLSELSIITFDGNNAALYSMASYIL 1467

Query: 1569 TRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL 1628
             R        ++    + N+   G +     K ++VT     I + R  +  +    + +
Sbjct: 1468 VR-IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR-KVEVDSIVV 1525

Query: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVP--------SSYGGQLCGLC 1680
            P+  +   ++I  S ++ ++ T  GL +++  SHL  +           SSY   LCG+C
Sbjct: 1526 PLPFSSQELSIEDSGSMYVITTPAGLIIKW--SHLTGIIDIHFGFRFNLSSYTEGLCGIC 1583

Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQ-LGA---AWKLPESSEPGCFLVGGKP-SSCQENSMA 1735
                N   DD+LR        +M+ +G    +W++ +S E    +   +P  +C E+  +
Sbjct: 1584 ----NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE----VTMRRPVRNCTEHDCS 1635

Query: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
                  C  L+N +  F  CH  V P+     C              C +L AY +LC +
Sbjct: 1636 Q-----CIDLLNRR-IFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNK 1686

Query: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPC-PDTCSS--INNPRDCPKALPCAESCECQK 1852
                  WR   +C + CP G  Y PC  PC   TC +        C   L   E C C+ 
Sbjct: 1687 FDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC---LNLREDCVCKV 1743

Query: 1853 GHIL---SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC- 1908
            G IL       C+P  +C CTD        GE W        L  C  + +I   +  C 
Sbjct: 1744 GTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCD 1803

Query: 1909 -KPNQIC 1914
             +P  +C
Sbjct: 1804 EEPTPVC 1810



 Score = 79.0 bits (193), Expect = 6e-14
 Identities = 114/557 (20%), Positives = 203/557 (36%), Gaps = 116/557 (20%)

Query: 1818 YSPCSSPCPDTCSSINNPRDCPKALPC-----AESC--ECQKGHILSGTS--------CV 1862
            Y PC++PC  TCS        P+AL C      E C   C K  IL   +        C+
Sbjct: 1281 YEPCATPCFKTCSD-------PEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCI 1333

Query: 1863 PLGQCGCT--DPAGSYHPVGERW--YTENTCTRLCTCSVHNNITCFQSTCKPNQIC---- 1914
            P+     T   PA    P+   W   T +  T     +    + C      P   C    
Sbjct: 1334 PVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYI 1393

Query: 1915 ----------WALD-----GLLRCRASGVGV----------------CQLPGESHYVSFD 1943
                      W+L+      +  C   G  V                C +  E   ++FD
Sbjct: 1394 CLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFD 1453

Query: 1944 GSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
            G+N ++    + +LV++    +     K S  ++   G        ++ +     ++ + 
Sbjct: 1454 GNNAALYSMASYILVRIPGEIIVAHIEKCSM-NQAPSGRISGLCFKKLNVTTPIHKIIVN 1512

Query: 2004 K-GHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG-NHLLEIEIP--- 2058
            +   +V ++S  V LP  SQ   +S++ S    ++    G+ +K+     +++I      
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQ--ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRF 1570

Query: 2059 --TTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE---FVNSWKDKDIDPSCQSLLVD 2113
              ++Y   +CG+C   N++ +D+L M +  +  +  +   F+ SW   +I+ S +  +  
Sbjct: 1571 NLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESW---EIEKSFEVTM-- 1622

Query: 2114 EQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEF 2173
                       P  NC   D      +C   L   ++  C  ++    F   C      +
Sbjct: 1623 ---------RRPVRNCTEHDC----SQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINY 1666

Query: 2174 GGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSC-SPSCWDLD 2232
               +   C AL A+ A C    +    WR   +C L CP    Y  C+  C + +C  L+
Sbjct: 1667 TYFWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTC--LN 1723

Query: 2233 GRCEGAKVPSACAEGCICQPGYVLSED---KCVPRSQCGCKDAHGGSIPLGKSWVSSGCT 2289
                G        E C+C+ G +L      +C+P  +C C D+       G+ W      
Sbjct: 1724 QWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIW------ 1777

Query: 2290 EKCVCTGGAIQCGDFRC 2306
                  GG  +C  ++C
Sbjct: 1778 -----NGGIDECTLYKC 1789



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 69/343 (20%), Positives = 127/343 (37%), Gaps = 60/343 (17%)

Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI--- 2386
            +CS+  +   +TFDG +  L    +Y+L++    +P  +    +E  +    P   I   
Sbjct: 1440 RCSMLSELSIITFDGNNAALYSMASYILVR----IPGEIIVAHIEKCSMNQAPSGRISGL 1495

Query: 2387 -FLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVS 2445
             F +  +TT     +  +   ++ V++  + +P+   E L +   G    + T   L++ 
Sbjct: 1496 CFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-LSIEDSGSMYVITTPAGLIIK 1554

Query: 2446 FG---GRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG---NSWEV 2499
            +    G  +              GLCG  +++  +D+ + +G +  N+   G    SWE+
Sbjct: 1555 WSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614

Query: 2500 -KTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFA 2558
             K+ +  +R P                     V  C+      +    C  L + +  F 
Sbjct: 1615 EKSFEVTMRRP---------------------VRNCT-----EHDCSQCIDLLN-RRIFI 1647

Query: 2559 ACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCE 2618
             CH  V+PE F E   ++     +        C  LS Y  LC +    +  WR    C 
Sbjct: 1648 PCHDKVSPEDFCEKMWINYTYFWN------YECDALSAYVALCNKFDICIQ-WRTPDYCS 1700

Query: 2619 SPCLQ----NPCQNDGQCREQGATFTCECEVGYGGGLCMEPRD 2657
              C +     PC    + R      TC  +  YG   C+  R+
Sbjct: 1701 LSCPEGKEYQPCVRPCEAR------TCLNQWFYGHTSCLNLRE 1737



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 26/99 (26%), Positives = 33/99 (33%), Gaps = 22/99 (22%)

Query: 1044 CPPNARYESCACPASCKS-------PRPSCGPLCREGCVCNPGFLFSDNH---CIQASSC 1093
            CP    Y+ C  P   ++          SC  L RE CVC  G +    H   CI    C
Sbjct: 1703 CPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNL-REDCVCKVGTILHRPHSAQCIPEKEC 1761

Query: 1094 NCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
             C  + D      E            W G   EC + +C
Sbjct: 1762 ACTDSEDQPRTAGE-----------IWNGGIDECTLYKC 1789


>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
          Length = 2250

 Score =  324 bits (830), Expect = 8e-88
 Identities = 298/1197 (24%), Positives = 482/1197 (40%), Gaps = 185/1197 (15%)

Query: 1108 WFSPN------CTEHCRCWPGSRVECQISQCGTHTVCQL----KNGQYGCHPYAGTATCL 1157
            +FSP+      C     C      +CQI Q    T CQ+     NG+ G         C 
Sbjct: 15   FFSPSGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNGRDGI--------CK 65

Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV-SCLSKVYV 1216
             +G  H+ TFDG ++ F G C+YI A+ CG+  +P + V   N  +    V SC   + +
Sbjct: 66   TWGQYHFETFDGIYYYFPGNCSYIFAKDCGD-LEPRYTVWVHNSPKCLGSVYSCYRSISL 124

Query: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLY 1276
                     + G      G  +TLP    + +F+     ++ ++T FG  + WDG   +Y
Sbjct: 125  FFSNQEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIY 183

Query: 1277 VTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVV 1336
            + +S  + GK CGLCGNY+    +D + L      D     NSW     +D +C      
Sbjct: 184  LKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSD 243

Query: 1337 NSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLC 1396
                C S + +  +    C  L+    PF +C  ++    +  SC+ D+C         C
Sbjct: 244  FPNPCSSGMPAFEAIFFKCQILLQF--PFLSCHEYIDPYLYIASCVNDLCKTDD-DETYC 300

Query: 1397 THMSTMTTTCQDAGHAVKPWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455
               +     C  AG+ ++ WR+    C   C  +  +  C   CP TC      +  +  
Sbjct: 301  RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLH 360

Query: 1456 CVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCESNNRIRC 1514
            C++ C C  G V+    CI    C C  H  G  + VG +  +  C E CVC        
Sbjct: 361  CLDGCYCPDGLVMDNGTCISLENCPCGFH--GLAYSVGSK-IEQECTE-CVCVGG----- 411

Query: 1515 QPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWS 1574
              W C  Q+          C  Q    C+  GD H+ TFDG  + F+G C Y+L +    
Sbjct: 412  -VWNCTEQD----------CPVQ----CSVVGDSHFTTFDGRHYSFIGMCQYILVK---G 453

Query: 1575 RSQDSYFVV--SATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632
              +D + +    A  E   G++ +  I  +    F+  ++L RG +++ + ++     + 
Sbjct: 454  TGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG----FN 509

Query: 1633 AQGRVTIR-LSSNLVLLYTNFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLD 1689
              G V I+ LSS  +LL T FGL++ +  DG  +  + + S++  +  GLCG +N N  D
Sbjct: 510  LNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCGTFNGNIRD 568

Query: 1690 DNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP--SSCQENSMADAWNKNCAILIN 1747
            D L P   + G       AW++  +    CF     P    C  N     +  +C ++  
Sbjct: 569  DFLSPSGMIEGTPQLHANAWRVSST----CFAPVHVPVVDPCNINQQNIGYAAHCDVI-- 622

Query: 1748 PQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNR-T 1806
             Q  F+ CH  + P   +  C H  C  K  ++ LC +L  YA LC Q G    +R + +
Sbjct: 623  HQELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQIS 680

Query: 1807 FCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS--CVPL 1864
            FC + C  G  Y  CSS C  +C S+++P  C     CAE C C +G     T   CVP+
Sbjct: 681  FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPI 738

Query: 1865 GQCGCTDPAGSYHPVGERWYTENTCTRLCTCS---------------------------- 1896
              C C      Y P GE   T +    LC CS                            
Sbjct: 739  FHCRCHYRGSVYQP-GELIPTPSG---LCQCSNGTVKCDELATPSAVHICPEGKEYFDCR 794

Query: 1897 ----------VHNNITC----FQSTCKPNQICWA---------LDGLLRCRASGV-GVCQ 1932
                      V+   TC       TC P+  C +           G+  C       VC 
Sbjct: 795  FPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCT 854

Query: 1933 LPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVY 1992
            + G+ HY SFDG  +     C + L+K    +       + A+++K              
Sbjct: 855  IYGDRHYYSFDGLEYDYISDCQVFLIKSADDS----DISVIAQNKK-------------- 896

Query: 1993 IDIYDAQVTLQKGHRVLINSKQVTL---PAISQIPGVSVKSSSIYSIVNIKIGVQVKF-- 2047
               +D  +   K   + +   ++ L   P   +  G  +++ S Y +      + V F  
Sbjct: 897  --CFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPE 954

Query: 2048 -------DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
                   D    + I++   +  K+ G+CGNF+    +++   ++    +   F +SW  
Sbjct: 955  KDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-- 1012

Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
                  C+S   DE   P E  +N            A+++C + L + ++A C + ID+T
Sbjct: 1013 --ALGQCES--PDETIKPCEAHQN--------KFPYAKKEC-SILYSDIFASCRNVIDVT 1059

Query: 2161 PFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
             F  +C      C  GG  + LC ++ A+   C  +G+    WR+S+ C L+C  Y+
Sbjct: 1060 SFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYN 1115



 Score =  272 bits (696), Expect = 3e-72
 Identities = 271/1148 (23%), Positives = 448/1148 (39%), Gaps = 168/1148 (14%)

Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
            C   G  H+ TFDG  ++F G C+Y+  + C          V  + +  G +   S  ++
Sbjct: 64   CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY--SCYRS 121

Query: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
            + +   +     + G ++  NG  + LP  +  G++ I   ++ +L+ T FG  + +DG 
Sbjct: 122  ISLFFSNQEEIRIYGHEIKKNGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGI 179

Query: 1662 HLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFL 1721
              + + +   + G+ CGLCGNYN+   DD +        D      +W +    +  C L
Sbjct: 180  SGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVL 239

Query: 1722 VGGK-PSSCQENSMA-DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDT 1779
                 P+ C     A +A    C IL+  Q PF  CH+ + P    ASCV+  C T  D 
Sbjct: 240  TPSDFPNPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE 297

Query: 1780 TALCRSLQAYASLCAQAGQA-PAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRD 1837
            T  CR+   YA  C+ AG     WR+    C  +C     +  C S CP TC+     + 
Sbjct: 298  T-YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTF---EKQ 353

Query: 1838 CPKA-LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
            C  + L C + C C  G ++   +C+ L  C C     +Y  VG +   E  CT  C C 
Sbjct: 354  CLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYS-VGSK--IEQECTE-CVC- 408

Query: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLV 1956
            V     C +  C P Q                  C + G+SH+ +FDG ++S    C  +
Sbjct: 409  VGGVWNCTEQDC-PVQ------------------CSVVGDSHFTTFDGRHYSFIGMCQYI 449

Query: 1957 LVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYI---DIYDAQVTLQKGHRVLINSK 2013
            LVK          F I+ +    E       L  + +   D ++ QVTL +G ++L +  
Sbjct: 450  LVK----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPN 505

Query: 2014 Q-VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF--DGNHLLEIEIPTTYYGKVCGMCG 2070
            Q   L  I +I  +S    S++ ++    G+++ F  DG  +  I++ + +  +  G+CG
Sbjct: 506  QGFNLNGIVEIQTLS----SLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCG 560

Query: 2071 NFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCR 2130
             FN    D+ + PS  +  +     N+W+   +  +C + +      P    +   G   
Sbjct: 561  TFNGNIRDDFLSPSGMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNINQQNIGYAA 617

Query: 2131 AADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGAT 2190
              D+          +   ++A C   I    +   C +  C+ G     LC AL  +   
Sbjct: 618  HCDV----------IHQELFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665

Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
            C   G+        SFC + C     Y +C   C  SC  L       +    CAEGC C
Sbjct: 666  CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLS---SPEQCSDDCAEGCNC 722

Query: 2251 QPG--YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPS 2308
              G  Y  + + CVP   C C   + GS+      + +  +  C C+ G ++C +   PS
Sbjct: 723  PEGKFYEDTLNFCVPIFHCRCH--YRGSVYQPGELIPTP-SGLCQCSNGTVKCDELATPS 779

Query: 2309 GSH------------------------CQLTSDN--------SNSNCVS----------- 2325
              H                        C+ T  N         +S C+S           
Sbjct: 780  AVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRR 839

Query: 2326 --------DKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRN 2377
                         C++YGD  Y +FDG  Y         LIK+ D        + V  +N
Sbjct: 840  GMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSAD-----DSDISVIAQN 894

Query: 2378 KMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV 2437
            K       +  + V+ +V   ++ L          QK +  +  N+     LW    Y+V
Sbjct: 895  KKCFDNDIVCSKSVLISVGDTEIYLND----TPYKQKQSGFFLENKS-TYQLWKAGYYIV 949

Query: 2438 TDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG 2494
              F   ++ + +  +    I +   ++  +SGLCGN+DK   NDM   +    +N   FG
Sbjct: 950  VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009

Query: 2495 NSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQ-LASNSTQACRVLADP 2553
            +SW +   ++        P E               +  C   Q     + + C +L   
Sbjct: 1010 DSWALGQCES--------PDE--------------TIKPCEAHQNKFPYAKKECSILY-- 1045

Query: 2554 QGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRD 2613
               FA+C   +    F ++C  D C+     + E L C  ++ YA  C + G ++  WR 
Sbjct: 1046 SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL-CTSIAAYAYKCCQEGISI-HWRS 1103

Query: 2614 RTLCESPC 2621
             T+C   C
Sbjct: 1104 STVCSLDC 1111



 Score =  209 bits (532), Expect = 3e-53
 Identities = 208/848 (24%), Positives = 327/848 (38%), Gaps = 140/848 (16%)

Query: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPL--CREGCVCNPGFLFSDNHCIQASSCNCF 1096
            T++C  +  +  C   CP +C   +   G    C +GC C  G +  +  CI   +C C 
Sbjct: 328  TDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCG 387

Query: 1097 YNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATC 1156
            ++   Y  G++     CTE                      C    G + C        C
Sbjct: 388  FHGLAYSVGSK-IEQECTE----------------------CVCVGGVWNCTEQDCPVQC 424

Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYV 1216
             V GD H+ TFDGRH+ F+G C YIL +  G   D F     K   +   G+ CL  + +
Sbjct: 425  SVVGDSHFTTFDGRHYSFIGMCQYILVK--GTGKDKFTITLQKAPCEQNLGLVCLQSITL 482

Query: 1217 TLPE---STVTLLKGRRTLVGGQQVTLPAIPSKGVFLGA-------SGRFVELQTEFGLR 1266
             L +     VTL  GR    GGQ +T    P++G  L         S  F+ L+T FGL+
Sbjct: 483  ILEDDFNKQVTL--GR----GGQILT---SPNQGFNLNGIVEIQTLSSLFILLKTTFGLK 533

Query: 1267 VRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
            + +  D +++Y+ ++S +  +  GLCG ++GN  +D L   G   G  +   N+W+    
Sbjct: 534  ILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV--- 590

Query: 1326 EDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLD 1384
                C  +  V+ P  D     +    G+       H   F  C +++    ++  C  D
Sbjct: 591  -SSTC--FAPVHVPVVD-PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHD 646

Query: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
             C  +     LC  ++     C   G  +    +  FC + C     Y  C+  C  +C 
Sbjct: 647  AC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCI 704

Query: 1445 SGFSGMFCSDRCVEACECNPG-FVLSGLE-CIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502
            S  S   CSD C E C C  G F    L  C+P   C C H  GS ++ GE    P    
Sbjct: 705  SLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC-HYRGSVYQPGE--LIPTPSG 761

Query: 1503 LCVCESNNRIRCQPWRC-RAQEFCGQQDGIYGCH-------AQGA------------ATC 1542
            LC C SN  ++C       A   C +    + C        A G              TC
Sbjct: 762  LCQC-SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTC 820

Query: 1543 TAS---------------------------------GDPHYLTFDGALHHFMGTCTYVLT 1569
            T S                                 GD HY +FDG  + ++  C   L 
Sbjct: 821  TPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLI 880

Query: 1570 RPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALP 1629
            +     + DS   V A N+ +    ++   K+V ++V D  I L          ++    
Sbjct: 881  K----SADDSDISVIAQNK-KCFDNDIVCSKSVLISVGDTEIYLND------TPYKQKQS 929

Query: 1630 VWLAQGRVTIRL---SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNN 1686
             +  + + T +L      +V+ +    + + +D    + + V   +  +L GLCGN++  
Sbjct: 930  GFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKC 989

Query: 1687 SLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILI 1746
            + +D    +     ++   G +W L +   P   +   KP    +N    A  K C+IL 
Sbjct: 990  TSNDMTTSNNLEVRNARVFGDSWALGQCESPDETI---KPCEAHQNKFPYA-KKECSILY 1045

Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRN 1804
            +    F+ C  V+   S   +C    C     GD   LC S+ AYA  C Q G +  WR+
Sbjct: 1046 S--DIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRS 1103

Query: 1805 RTFCPMRC 1812
             T C + C
Sbjct: 1104 STVCSLDC 1111



 Score =  180 bits (456), Expect = 2e-44
 Identities = 163/706 (23%), Positives = 274/706 (38%), Gaps = 94/706 (13%)

Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988
            G+C+  G+ H+ +FDG  +  P  C+ +  K C      P + +   +  +  G+     
Sbjct: 62   GICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCY 119

Query: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048
              + +   + +     GH +  N   +TLP    I  + ++  + Y +V    G  + +D
Sbjct: 120  RSISLFFSNQEEIRIYGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWD 177

Query: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQ 2108
            G   + +++   + GK CG+CGN+ND + D+ ++  ++     + F NSW  +   P   
Sbjct: 178  GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQ--TPDDT 235

Query: 2109 SLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN 2168
              ++     P     NP  +   A       KC+  L+ P +  C   ID   ++  C N
Sbjct: 236  KCVLTPSDFP-----NPCSSGMPA-FEAIFFKCQILLQFP-FLSCHEYIDPYLYIASCVN 288

Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYSSYTNCLPSCSPS 2227
             LC+     +  C+A   +   C   G     WR+    C  +C     + +C+  C P+
Sbjct: 289  DLCKTDD-DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPT 347

Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
            C   + +C G+ +   C +GC C  G V+    C+    C C   HG +  +G S +   
Sbjct: 348  C-TFEKQCLGSNL--HCLDGCYCPDGLVMDNGTCISLENCPC-GFHGLAYSVG-SKIEQE 402

Query: 2288 CTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSY 2347
            CTE CVC GG   C +  CP                      QCSV GD  + TFDG  Y
Sbjct: 403  CTE-CVCVGGVWNCTEQDCP---------------------VQCSVVGDSHFTTFDGRHY 440

Query: 2348 RLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV----YGYKVQLQ 2403
               G   Y+L+K       G +   +  +         +   + IT +    +  +V L 
Sbjct: 441  SFIGMCQYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLG 495

Query: 2404 AGLELVVNNQKMAVPYRPNEHLRV-------TLWGQRLYLVTDFELVVSFG-GRKNAVIS 2455
             G +++ +         PN+   +       TL    + L T F L + F    +   I 
Sbjct: 496  RGGQILTS---------PNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQ 546

Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
            L S ++    GLCG ++ N ++D + PSG +        N+W V    +    P  +P  
Sbjct: 547  LTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV---SSTCFAPVHVPV- 602

Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVL 2575
                           V  C+  Q        C V+   Q  FA CH  ++P  + + C  
Sbjct: 603  ---------------VDPCNINQQNIGYAAHCDVI--HQELFAPCHIYISPGLYYQLCRH 645

Query: 2576 DLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            D C            C  L+ YA LC + G  +      + C   C
Sbjct: 646  DACKC-----GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC 686



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 86/371 (23%), Positives = 145/371 (39%), Gaps = 47/371 (12%)

Query: 2285 SSGCTEKCV----CTG-GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
            S  C  +C+    C+  G   C  F+   G+ CQ+  +  N      +   C  +G   +
Sbjct: 19   SGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNG-----RDGICKTWGQYHF 72

Query: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIF-LQEVITTVYGY 2398
             TFDG  Y   G  +Y+  K    L    EP      +       S++     I+  +  
Sbjct: 73   ETFDGIYYYFPGNCSYIFAKDCGDL----EPRYTVWVHNSPKCLGSVYSCYRSISLFFSN 128

Query: 2399 KVQLQA-GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
            + +++  G E+  N   + +P    + + +      + + T F   +++ G     + L 
Sbjct: 129  QEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIYLKLS 187

Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTED--ALLRFPRAIPAE 2515
              ++G   GLCGNY+  + +D ++     T+++  F NSW V+T D    +  P   P  
Sbjct: 188  EDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFP-- 245

Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNST-QACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
                            + CS    A  +    C++L   Q PF +CH+ + P  +   CV
Sbjct: 246  ----------------NPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCV 287

Query: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDR-TLCESPCLQNPCQNDG-QC 2632
             DLC   D    +E  C+  + YA  C  AG  +  WRD    C   C  +    D   C
Sbjct: 288  NDLCKTDD----DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISC 343

Query: 2633 REQGATFTCEC 2643
                 TF  +C
Sbjct: 344  CPPTCTFEKQC 354



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 98/441 (22%), Positives = 159/441 (36%), Gaps = 58/441 (13%)

Query: 1126 ECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP 1185
            + ++  CG        N    C  +     C +  +   +TFDG +       +YIL + 
Sbjct: 1411 DVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI 1470

Query: 1186 CGNSTDPFFRVTAKNEE-QGQEGVSCLSKVYVTLPESTVTLLK-GRRTLVGGQQVTLPAI 1243
             G          + N+   G+    C  K+ VT P   + + +  R+  V    V LP  
Sbjct: 1471 PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLP-F 1529

Query: 1244 PSKGVFLGASGRFVELQTEFGLRVRWD---GDQQLYVTVSSTYSGKLCGLCGNYDGNSDN 1300
             S+ + +  SG    + T  GL ++W    G   ++       S    GLCG  + + D+
Sbjct: 1530 SSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDD 1589

Query: 1301 DHLKLDGSPAGDKEELG---NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGR 1357
            D    +G+   + E++G    SW+ ++  +   ++  V N    D            C +
Sbjct: 1590 DLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRR-PVRNCTEHD------------CSQ 1636

Query: 1358 LVD--THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKP 1415
             +D      F  C   V    F +   ++   F   +   C  +S     C      ++ 
Sbjct: 1637 CIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692

Query: 1416 WREPHFCPMACPPNSKYSLCAKPC-PDTC-HSGFSGMFCSDRCVEACECNPGFVL---SG 1470
            WR P +C ++CP   +Y  C +PC   TC +  F G        E C C  G +L     
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHS 1752

Query: 1471 LECIPRSQCGCLHPAGSYFKVGERW---------YK-----------PGCKE--LCVCES 1508
             +CIP  +C C          GE W         YK           P C E    VCE 
Sbjct: 1753 AQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCER 1812

Query: 1509 NNRI---RCQPWRCRAQEFCG 1526
               +       W C ++E CG
Sbjct: 1813 EAEVVMGIIDKWTCCSKEVCG 1833



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 100/427 (23%), Positives = 162/427 (37%), Gaps = 64/427 (14%)

Query: 1509 NNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL 1568
            N+ I C  W C  +                   C+   +   +TFDG         +Y+L
Sbjct: 1427 NSDICCPEWECPCR-------------------CSMLSELSIITFDGNNAALYSMASYIL 1467

Query: 1569 TRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL 1628
             R        ++    + N+   G +     K ++VT     I + R  +  +    + +
Sbjct: 1468 VR-IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR-KVEVDSIVV 1525

Query: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVP--------SSYGGQLCGLC 1680
            P+  +   ++I  S ++ ++ T  GL +++  SHL  +           SSY   LCG+C
Sbjct: 1526 PLPFSSQELSIEDSGSMYVITTPAGLIIKW--SHLTGIIDIHFGFRFNLSSYTEGLCGIC 1583

Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQ-LGA---AWKLPESSEPGCFLVGGKP-SSCQENSMA 1735
                N   DD+LR        +M+ +G    +W++ +S E    +   +P  +C E+  +
Sbjct: 1584 ----NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE----VTMRRPVRNCTEHDCS 1635

Query: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
                  C  L+N +  F  CH  V P+     C              C +L AY +LC +
Sbjct: 1636 Q-----CIDLLNRR-IFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNK 1686

Query: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPC-PDTCSS--INNPRDCPKALPCAESCECQK 1852
                  WR   +C + CP G  Y PC  PC   TC +        C   L   E C C+ 
Sbjct: 1687 FDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC---LNLREDCVCKV 1743

Query: 1853 GHIL---SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC- 1908
            G IL       C+P  +C CTD        GE W        L  C  + +I   +  C 
Sbjct: 1744 GTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCD 1803

Query: 1909 -KPNQIC 1914
             +P  +C
Sbjct: 1804 EEPTPVC 1810



 Score = 79.0 bits (193), Expect = 6e-14
 Identities = 114/557 (20%), Positives = 203/557 (36%), Gaps = 116/557 (20%)

Query: 1818 YSPCSSPCPDTCSSINNPRDCPKALPC-----AESC--ECQKGHILSGTS--------CV 1862
            Y PC++PC  TCS        P+AL C      E C   C K  IL   +        C+
Sbjct: 1281 YEPCATPCFKTCSD-------PEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCI 1333

Query: 1863 PLGQCGCT--DPAGSYHPVGERW--YTENTCTRLCTCSVHNNITCFQSTCKPNQIC---- 1914
            P+     T   PA    P+   W   T +  T     +    + C      P   C    
Sbjct: 1334 PVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYI 1393

Query: 1915 ----------WALD-----GLLRCRASGVGV----------------CQLPGESHYVSFD 1943
                      W+L+      +  C   G  V                C +  E   ++FD
Sbjct: 1394 CLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFD 1453

Query: 1944 GSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
            G+N ++    + +LV++    +     K S  ++   G        ++ +     ++ + 
Sbjct: 1454 GNNAALYSMASYILVRIPGEIIVAHIEKCSM-NQAPSGRISGLCFKKLNVTTPIHKIIVN 1512

Query: 2004 K-GHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG-NHLLEIEIP--- 2058
            +   +V ++S  V LP  SQ   +S++ S    ++    G+ +K+     +++I      
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQ--ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRF 1570

Query: 2059 --TTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE---FVNSWKDKDIDPSCQSLLVD 2113
              ++Y   +CG+C   N++ +D+L M +  +  +  +   F+ SW   +I+ S +  +  
Sbjct: 1571 NLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESW---EIEKSFEVTM-- 1622

Query: 2114 EQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEF 2173
                       P  NC   D      +C   L   ++  C  ++    F   C      +
Sbjct: 1623 ---------RRPVRNCTEHDC----SQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINY 1666

Query: 2174 GGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSC-SPSCWDLD 2232
               +   C AL A+ A C    +    WR   +C L CP    Y  C+  C + +C  L+
Sbjct: 1667 TYFWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTC--LN 1723

Query: 2233 GRCEGAKVPSACAEGCICQPGYVLSED---KCVPRSQCGCKDAHGGSIPLGKSWVSSGCT 2289
                G        E C+C+ G +L      +C+P  +C C D+       G+ W      
Sbjct: 1724 QWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIW------ 1777

Query: 2290 EKCVCTGGAIQCGDFRC 2306
                  GG  +C  ++C
Sbjct: 1778 -----NGGIDECTLYKC 1789



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 69/343 (20%), Positives = 127/343 (37%), Gaps = 60/343 (17%)

Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI--- 2386
            +CS+  +   +TFDG +  L    +Y+L++    +P  +    +E  +    P   I   
Sbjct: 1440 RCSMLSELSIITFDGNNAALYSMASYILVR----IPGEIIVAHIEKCSMNQAPSGRISGL 1495

Query: 2387 -FLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVS 2445
             F +  +TT     +  +   ++ V++  + +P+   E L +   G    + T   L++ 
Sbjct: 1496 CFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-LSIEDSGSMYVITTPAGLIIK 1554

Query: 2446 FG---GRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG---NSWEV 2499
            +    G  +              GLCG  +++  +D+ + +G +  N+   G    SWE+
Sbjct: 1555 WSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614

Query: 2500 -KTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFA 2558
             K+ +  +R P                     V  C+      +    C  L + +  F 
Sbjct: 1615 EKSFEVTMRRP---------------------VRNCT-----EHDCSQCIDLLN-RRIFI 1647

Query: 2559 ACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCE 2618
             CH  V+PE F E   ++     +        C  LS Y  LC +    +  WR    C 
Sbjct: 1648 PCHDKVSPEDFCEKMWINYTYFWN------YECDALSAYVALCNKFDICIQ-WRTPDYCS 1700

Query: 2619 SPCLQ----NPCQNDGQCREQGATFTCECEVGYGGGLCMEPRD 2657
              C +     PC    + R      TC  +  YG   C+  R+
Sbjct: 1701 LSCPEGKEYQPCVRPCEAR------TCLNQWFYGHTSCLNLRE 1737



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 26/99 (26%), Positives = 33/99 (33%), Gaps = 22/99 (22%)

Query: 1044 CPPNARYESCACPASCKS-------PRPSCGPLCREGCVCNPGFLFSDNH---CIQASSC 1093
            CP    Y+ C  P   ++          SC  L RE CVC  G +    H   CI    C
Sbjct: 1703 CPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNL-REDCVCKVGTILHRPHSAQCIPEKEC 1761

Query: 1094 NCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
             C  + D      E            W G   EC + +C
Sbjct: 1762 ACTDSEDQPRTAGE-----------IWNGGIDECTLYKC 1789


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  298 bits (762), Expect = 6e-80
 Identities = 315/1277 (24%), Positives = 487/1277 (38%), Gaps = 222/1277 (17%)

Query: 1152 GTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211
            G   C  +G+ HY TFDG  F F G C Y  A  C  S   F  V  K      E  + +
Sbjct: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEF-AVHLKRGPGQAEAPAGV 91

Query: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271
              + +T+ + T+ L +    ++ G  V+ P   S G+ +  S  + ++ +  GL + W+ 
Sbjct: 92   ESILLTIKDDTIYLTR-HLAVLNGAVVSTPHY-SPGLLIEKSDAYTKVYSRAGLTLMWNR 149

Query: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG---SPAGDKEELGNSWQTDQDEDQ 1328
            +  L + + + +    CGLCG+Y+G         DG   SP     E GN  + +Q  D 
Sbjct: 150  EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL----EFGNMQKINQP-DV 204

Query: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388
             C+  +   +P+  S  ++       C RL+ T   F  C   V    +  +C  D C  
Sbjct: 205  VCEDPEEEVAPASCSEHRAE------CERLL-TAEAFADCQDLVPLEPYLRACQQDRCRC 257

Query: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFS 1448
             G    +C+ ++  +  C  AG     WR    CP  CP N  Y     PC DTC     
Sbjct: 258  PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEV 317

Query: 1449 GMFCSDRCVEACECNPGFVLSGLE---CIPRSQCGCLHPAGSYFKVGERWYKPGCK---- 1501
               C +  ++ C C  G V   +    C+P SQC C        ++    Y PG +    
Sbjct: 318  SSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHC--------RLHGHLYTPGQEITND 369

Query: 1502 -ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560
             E CVC +        W C+     G              TC   G  H  TFDG  + F
Sbjct: 370  CEQCVCNAGR------WVCKDLPCPG--------------TCALEGGSHITTFDGKTYTF 409

Query: 1561 MGTCTYVLTRPCWSRSQDSYFVVS-----ATNENRGGILEVSYI--KAVHVTVFDLSISL 1613
             G C YVL +       DSY ++       + + +  +  V  +  K  +V VF    S 
Sbjct: 410  HGDCYYVLAK---GDHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGS- 465

Query: 1614 LRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSS 1671
                 V+LN  +V LP   A   V  R SS  +++    G++++   + +++  VT+  +
Sbjct: 466  -----VLLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQA 519

Query: 1672 YGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPS-SCQ 1730
              GQ+ GLCGN+N    DD       +          WK   S       +    S + +
Sbjct: 520  SQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIE 579

Query: 1731 ENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYA 1790
              + A+ W   C++L   + PF +CH  V P   +  C +  C  + +   LC +L +YA
Sbjct: 580  SANYAEHW---CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYA 636

Query: 1791 SLCAQAG-QAPAWRNRTFCPM---RCPPGSSYSPCSSPCPDTCSSINN----------PR 1836
              C   G     WR    C      CP    +    + C  TC S++           P 
Sbjct: 637  RACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPV 695

Query: 1837 D---CP---------KALPCA---------------------ESCECQKGHI------LS 1857
            D   CP         + +P A                     E C C+ G +      L 
Sbjct: 696  DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLI 755

Query: 1858 GTSCV-PLGQCGCTD-----------------PAGSYH---------PVGERWYTENTCT 1890
            G SC  P     C++                  AG YH         P G        C 
Sbjct: 756  GQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCV 815

Query: 1891 --RLCTCSVHNN----------ITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESH 1938
              + C C VHNN          + C   TCK  +  W        +A   G C + G  H
Sbjct: 816  VEKECPC-VHNNDLYSSGAKIKVDCNTCTCKRGR--WVCT-----QAVCHGTCSIYGSGH 867

Query: 1939 YVSFDGSNHSIPDACTLVLVK-VCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYD 1997
            Y++FDG  +     C+ V V+  C    +L  F I  ++    G T       + I +  
Sbjct: 868  YITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC-GTTGVTCSKAIKIFMGR 926

Query: 1998 AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEI 2057
             ++ L+  HRV+I   +            + +    Y +V    G+ V +D    + I++
Sbjct: 927  TELKLEDKHRVVIQRDE------GHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKL 980

Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117
              +Y G VCG+CGNF+    ++       V +S+ +F NSWK+    P+C  +       
Sbjct: 981  APSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDV------- 1030

Query: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA--NTLCEFGG 2175
                  NP         R   EK  + L++ V++ C S++D  PF   C   +  C+ GG
Sbjct: 1031 ----STNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGG 1086

Query: 2176 LYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSC 2228
              +  C A+ ++   C  +G     WR    CP+ C  Y+        Y  C      +C
Sbjct: 1087 DCECFCSAVASYAQECTKEG-ACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETC 1145

Query: 2229 WDLDGRCEGAKVPSACAEGCI--C---QPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGK 2281
              ++G      V  +  EGC   C   +P Y     KCV   +CGC  +D H    P G 
Sbjct: 1146 RTINGIHSNISV--SYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH---YPPGA 1200

Query: 2282 SWVSSGCTEKCVCTGGA 2298
            S  +    + CVCT  +
Sbjct: 1201 SVPTEETCKSCVCTNSS 1217



 Score =  251 bits (640), Expect = 9e-66
 Identities = 284/1188 (23%), Positives = 445/1188 (37%), Gaps = 203/1188 (17%)

Query: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEV- 1596
            G   C+  G+ HY TFDG +  F G C Y     C    + SY   +   +   G  E  
Sbjct: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC----RGSYKEFAVHLKRGPGQAEAP 88

Query: 1597 SYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
            + ++++ +T+ D +I L R   V LNG  V+ P +     + I  S     +Y+  GL +
Sbjct: 89   AGVESILLTIKDDTIYLTRHLAV-LNGAVVSTPHY--SPGLLIEKSDAYTKVYSRAGLTL 145

Query: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYN-----NNSLDDNLRPDRKLAGDSMQLGAAWKL 1711
             ++    + + + + +    CGLCG+YN     +  L D +       G+  ++     +
Sbjct: 146  MWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVV 205

Query: 1712 PESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHG 1771
             E  E         P+SC E+         C  L+  +  F+ C  +VP +    +C   
Sbjct: 206  CEDPEEEV-----APASCSEH------RAECERLLTAEA-FADCQDLVPLEPYLRACQQD 253

Query: 1772 QCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
            +C   G  T +C ++  ++  C+ AG  P  WR  T CP  CP    Y    SPC DTCS
Sbjct: 254  RCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCS 313

Query: 1831 SINNPRDCPKALPCAESCECQKGHI---LSGTSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
             +     C +     + C C +G +   +  + CVP+ QC C      Y P  E     N
Sbjct: 314  HLEVSSLCEEHR--MDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQE---ITN 368

Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947
             C + C C+    +      CK           L C     G C L G SH  +FDG  +
Sbjct: 369  DCEQ-CVCNAGRWV------CKD----------LPCP----GTCALEGGSHITTFDGKTY 407

Query: 1948 SIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ---VTLQK 2004
            +    C  VL K  H        +++       G T+     +  + + D +   V  + 
Sbjct: 408  TFHGDCYYVLAKGDHNDSYALLGELAPC-----GSTDKQTCLKTVVLLADKKKNVVVFKS 462

Query: 2005 GHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV--QVKFDGNHLLEIEIPTTYY 2062
               VL+N  QV LP ++    V  + SS + +V++ IGV  QV+      L + +     
Sbjct: 463  DGSVLLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQ 521

Query: 2063 GKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQ 2122
            G+V G+CGNFN  E D+    S  V  + + F N+WK +    SC   L        +  
Sbjct: 522  GQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS---SCHDKL--------DWL 570

Query: 2123 ENP-SGNCRAADLRRAREKCEAALRAPV-WAQCASRIDLTPFLVDCANTLCEFGGLYQAL 2180
            ++P S N  +A+   A   C    +    + +C S +D   +   C    C        L
Sbjct: 571  DDPCSLNIESANY--AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCL 628

Query: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLE---CPAYSSYTNCLPSCSPSCWDL---DGR 2234
            C AL ++   C ++G+    WR    C  +   CP    +   L +C  +C  L   D  
Sbjct: 629  CAALSSYARACTAKGVMLWGWREH-VCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSH 687

Query: 2235 CEGAKVPSACAEGCICQPGYVLSED-KCVP----------------------RSQCGCKD 2271
            C     P    +GC C     L E  +CVP                        +C C+D
Sbjct: 688  CLEGFAP---VDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRD 744

Query: 2272 ----------------------------AHGGSIP-------LGKSWVSSGCTEKCVCTG 2296
                                        A   S P       L   +  + C   CVC  
Sbjct: 745  GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD 804

Query: 2297 GAIQCGDFRCPSGSHCQLTSDNSN-----------SNCVSDKSE----------QCSVYG 2335
            G +  G   C     C    +N             + C   +             CS+YG
Sbjct: 805  GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG 864

Query: 2336 DPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV 2395
               Y+TFDG  Y   G  +YV ++        +    +   N +    + +   + I   
Sbjct: 865  SGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITEN-VPCGTTGVTCSKAIKIF 923

Query: 2396 YGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLW--GQRLYLVTDFELVVSFGGRKNAV 2453
             G   + +  LE   +  ++ +      H+  T    GQ L + +   ++V +  R    
Sbjct: 924  MG---RTELKLE---DKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVF 977

Query: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
            I L   Y+G V GLCGN+D    ND       +  +   FGNSW            +  P
Sbjct: 978  IKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW------------KEAP 1025

Query: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573
               +       + T  +    +P +  S + + C +L      F+ CH  V P+PF E C
Sbjct: 1026 TCPD-------VSTNPEPCSLNPHR-RSWAEKQCSIL--KSSVFSICHSKVDPKPFYEAC 1075

Query: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            V D CS  D     E  C  ++ YA  C + GA +  WR   LC   C
Sbjct: 1076 VHDSCSC-DTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFC 1121



 Score =  216 bits (549), Expect = 3e-55
 Identities = 300/1138 (26%), Positives = 420/1138 (36%), Gaps = 104/1138 (9%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3774 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3830

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3891 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3949

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3950 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 4006

Query: 705  ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
              T+ PT +P   T    PT  PT  T+  T +P   TT   PT  PT  T+ PT +P  
Sbjct: 4007 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 4064

Query: 759  PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-I 817
             TT T  PT +P     PT  P I T     PT  PT +    TTP   TT  T  P+  
Sbjct: 4065 TTT-TVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4122

Query: 818  PMEKPTLPTEETTTSVEETTIST---EKLTIPMEKPTISTEKPT-IPTEKPTISPEKLTI 873
              + PT     TTT+V  T   T      T P+   T  T  PT   T+ PT +P   T 
Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4182

Query: 874  -------PTEKLT-IPTEKPTIPIEETTIST---EKLTIPTEKPTISP--EKPTI-STEK 919
                   PT   T  PT   T PI E T S    E  T  T + T SP  E  T+ ST  
Sbjct: 4183 TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 4242

Query: 920  PTIP---TEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTI-STEKPTIPTEK 975
            P I    T  P+ PT  TT S      P    T SP     PT   T  S+  PT  T +
Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT--PTRGTTTGSSSAPTPSTVQ 4300

Query: 976  LTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTT 1035
             T  +     PT   T    + T LRP +PS        L  + +AP   + +   G T 
Sbjct: 4301 TTTTSAWTPTPTPLSTPSIIRTTGLRP-YPSSVLI-CCVLNDTYYAPGEEVYNGTYGDTC 4358

Query: 1036 TSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGFLFSD-NHCIQASSCN 1094
               + +  C     + + +CP++   P P+  P         P    S      +   C 
Sbjct: 4359 YFVNCSLSC--TLEFYNWSCPST---PSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP 4413

Query: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYG-------- 1146
             F  +   +    W+  +C     C   + VE    +C    +    NG           
Sbjct: 4414 DF--DPPRQENETWWLCDCFM-ATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDG 4470

Query: 1147 -CHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQ 1205
             C  +     C  +GDPHYVTFDG ++ + G CTY+L +    S D F            
Sbjct: 4471 CCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPN 4530

Query: 1206 EGVSCLSKVYVTLPESTVTLLKGRRTL-------VGGQQVTLPAIPSKGVFLGASG-RFV 1257
            + VSC  +  +   E+   L+K    +       V  Q V LP     G+ +  SG  +V
Sbjct: 4531 DKVSC-PRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP-YKKYGLEVYQSGINYV 4588

Query: 1258 ELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELG 1317
                E G+ V ++G           +     G CG     + +D +   G    + E   
Sbjct: 4589 VDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA 4648

Query: 1318 NSWQTDQDEDQEC------QKYQVVNSPSCDSSLQSSMSGPG-FCGRLVDTHGPFETCLL 1370
            + W  +      C       K   V  P    +       P   C  + D+   F  C  
Sbjct: 4649 DQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDS--LFAQCHA 4706

Query: 1371 HVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPH-FCPMACPPN 1429
             V    ++D+C+ D C   G   L C  +      C      +      H  C + CP +
Sbjct: 4707 LVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSH 4765

Query: 1430 SKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV--LSGLECIPRSQCGCLHPAGS 1487
             +Y  C      TC S  S    +   VE C C  G +    G +   ++ CGC+ P   
Sbjct: 4766 REYQACGPAEEPTCKSS-SSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT-CGCVGPDNV 4823

Query: 1488 YFKVGERWYKPGCKELCVC-ESNNRIRCQPWRCRAQEFCG-QQDGIY-GCHAQGAATC 1542
              + GE  ++  CK  CVC E  + I CQP RC  +      +DG Y       A TC
Sbjct: 4824 PREFGEH-FEFDCKN-CVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 4879



 Score =  200 bits (508), Expect = 2e-50
 Identities = 191/712 (26%), Positives = 279/712 (39%), Gaps = 108/712 (15%)

Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE-E 1980
            R R  G  VC   G  HY +FDG     P  C       C  +     +K  A H K   
Sbjct: 28   RTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGS-----YKEFAVHLKRGP 82

Query: 1981 GGTEA-FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039
            G  EA   +  + + I D  + L + H  ++N   V+ P  S  PG+ ++ S  Y+ V  
Sbjct: 83   GQAEAPAGVESILLTIKDDTIYLTR-HLAVLNGAVVSTPHYS--PGLLIEKSDAYTKVYS 139

Query: 2040 KIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK 2099
            + G+ + ++    L +E+ T +    CG+CG++N  +     + SD V  S  EF N  K
Sbjct: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNMQK 198

Query: 2100 DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159
                D  C+    +E+  PA   E+             R +CE  L A  +A C   + L
Sbjct: 199  INQPDVVCED--PEEEVAPASCSEH-------------RAECERLLTAEAFADCQDLVPL 243

Query: 2160 TPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTN 2219
             P+L  C    C   G    +C  +  F   C   G +P  WR ++ CP  CP    Y  
Sbjct: 244  EPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVY-- 301

Query: 2220 CLPSCSPSCWDLDGRCEGAKVPSACAE----GCICQPGYV---LSEDKCVPRSQCGCKDA 2272
             L S SP C D    C   +V S C E    GC C  G V   + +  CVP SQC C+  
Sbjct: 302  -LESGSP-CMDT---CSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCR-L 355

Query: 2273 HGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCS 2332
            HG     G+  +++ C E+CVC  G   C D  CP                       C+
Sbjct: 356  HGHLYTPGQE-ITNDC-EQCVCNAGRWVCKDLPCPG---------------------TCA 392

Query: 2333 VYGDPRYLTFDGFSYRLQGRMTYVLIKTV--DVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
            + G     TFDG +Y   G   YVL K    D      E       +K    ++ + L +
Sbjct: 393  LEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQTCLKTVVLLAD 452

Query: 2391 VITTVYGYKVQLQAGL-ELVVNNQKMAVPY---RPNE-HLRVTLWGQRLYLVTDFELVVS 2445
                V  +K      L EL VN   +   +   RP+  H+ V++            L V 
Sbjct: 453  KKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSM-------AIGVRLQVQ 505

Query: 2446 FGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKT--ED 2503
                    ++L    +G V GLCGN++    +D    SG +      F N+W+ ++   D
Sbjct: 506  LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 565

Query: 2504 AL--LRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACH 2561
             L  L  P ++  E                        A+ +   C +L   + PF  CH
Sbjct: 566  KLDWLDDPCSLNIES-----------------------ANYAEHWCSLLKKTETPFGRCH 602

Query: 2562 QTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRD 2613
              V P  + + C  D C+ Q+    E+  C  LS YA  C   G  L GWR+
Sbjct: 603  SAVDPAEYYKRCKYDTCNCQN---NEDCLCAALSSYARACTAKGVMLWGWRE 651



 Score =  165 bits (417), Expect = 6e-40
 Identities = 126/477 (26%), Positives = 199/477 (41%), Gaps = 79/477 (16%)

Query: 1070 CREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVEC 1127
            C  GCVC  G L  D    C+    C C +NND Y  GA+                +V+C
Sbjct: 796  CVSGCVCPDG-LMDDGRGGCVVEKECPCVHNNDLYSSGAK---------------IKVDC 839

Query: 1128 QISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C 1186
                      C  K G++ C       TC +YG  HY+TFDG+++ F G C+Y+  Q  C
Sbjct: 840  N--------TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 891

Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS 1245
            G NS+   F +  +N   G  GV+C   + + +  + + L    R ++   +    A  +
Sbjct: 892  GQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTT 951

Query: 1246 KGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
            + V     G+++ +++  G+ V WD    +++ ++ +Y G +CGLCGN+D  S+ND    
Sbjct: 952  REV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTR 1006

Query: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPF 1365
            D      + + GNSW+    E   C      N   C  +          C  L  +   F
Sbjct: 1007 DHMVVSSELDFGNSWK----EAPTCPDVS-TNPEPCSLNPHRRSWAEKQCSILKSS--VF 1059

Query: 1366 ETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP 1423
              C   V    F+++C+ D C     G     C+ +++    C   G  V  WR P  CP
Sbjct: 1060 SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCP 1118

Query: 1424 MAC----PPNS---KYSLCAKPCPDTC------HSGFSGMF---CSDRCVEACECNPGFV 1467
            + C    PP+     Y  C     +TC      HS  S  +   C  RC +     P + 
Sbjct: 1119 IFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKD---RPIYE 1175

Query: 1468 LSGLECIPRSQCGCLHPAGSYFKVGERWYKPG--------CKELCVCESNNRIRCQP 1516
                +C+   +CGC         V +  Y PG        CK  CVC +++++ C+P
Sbjct: 1176 EDLKKCVTADKCGCY--------VEDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1223



 Score =  164 bits (414), Expect = 1e-39
 Identities = 139/497 (27%), Positives = 206/497 (41%), Gaps = 81/497 (16%)

Query: 1436 AKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGSYFKVGER 1494
            +KP   +C +  +G + ++ CV  C C  G +  G   C+   +C C+H           
Sbjct: 777  SKPRALSCQTLAAGYYHTE-CVSGCVCPDGLMDDGRGGCVVEKECPCVH--------NND 827

Query: 1495 WYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFD 1554
             Y  G K    C   N   C+    R +  C Q      CH     TC+  G  HY+TFD
Sbjct: 828  LYSSGAKIKVDC---NTCTCK----RGRWVCTQAV----CHG----TCSIYGSGHYITFD 872

Query: 1555 GALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISL 1613
            G  + F G C+YV  +  C   S    F +   N   G    V+  KA+ + +    + L
Sbjct: 873  GKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRTELKL 931

Query: 1614 LRGCKVMLN---GHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPS 1670
                +V++    GH VA          T R     +++ ++ G+ V +D    V + +  
Sbjct: 932  EDKHRVVIQRDEGHHVAY---------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAP 982

Query: 1671 SYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQ 1730
            SY G +CGLCGN+++ S +D    D  +    +  G +WK      P C  V   P  C 
Sbjct: 983  SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----EAPTCPDVSTNPEPCS 1038

Query: 1731 ENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQ 1787
             N    +W  K C+IL      FS CH  V P+  + +CVH  C   T GD    C ++ 
Sbjct: 1039 LNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVA 1096

Query: 1788 AYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINN------ 1834
            +YA  C + G    WR    CP+ C    PP      Y PC +   +TC +IN       
Sbjct: 1097 SYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1156

Query: 1835 --------PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886
                    PR CPK  P  E  + +K        CV   +CGC     +++P G    TE
Sbjct: 1157 VSYLEGCYPR-CPKDRPIYEE-DLKK--------CVTADKCGCY-VEDTHYPPGASVPTE 1205

Query: 1887 NTCTRLCTCSVHNNITC 1903
             TC + C C+  + + C
Sbjct: 1206 ETC-KSCVCTNSSQVVC 1221



 Score =  162 bits (410), Expect = 4e-39
 Identities = 156/469 (33%), Positives = 196/469 (41%), Gaps = 83/469 (17%)

Query: 606  TIPSEKPNMPSEKPTIPSEKPTILTEKP--TIPSEKPTIPSEKPTISTEKPTVPTEEPTT 663
            T PS     PS  PT  +  P   T  P  T  +  P   +  P I+T     PT  P+ 
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 664  PTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEK 723
            P   TTT       PT  PS PT  PS PT  P  S   T  +T  PT +P     PT  
Sbjct: 1457 PISTTTTPP-----PTTTPSPPTTTPSPPTTTP--SPPTTTTTTPPPTTTPSP---PTTT 1506

Query: 724  PTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP 783
            P  P   +T  P     PT  P+ PT   T  P  PTT    PT +P  +T PT   T+P
Sbjct: 1507 PITPPASTTTLP-----PTTTPSPPTTTTTTPP--PTTTPSPPTTTP--ITPPTSTTTLP 1557

Query: 784  TEKPTIPTEKPTISTEEP--TTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTE 841
                T P+  PT +T  P  TTP+  TT +   P+I           TTT+   TT  + 
Sbjct: 1558 --PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTI-----------TTTTPPPTTTPSP 1604

Query: 842  KLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901
              T      T +T  PT     PT +P  +T PT   T+P   PT     TT S    T 
Sbjct: 1605 PTT------TTTTPPPTTTPSPPTTTP--ITPPTSTTTLP---PT-----TTPSPPPTTT 1648

Query: 902  PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEK 961
             T  PT +P  PT +T  P I T   T P   TT S+   T P      SP   T+ T  
Sbjct: 1649 TTPPPTTTPSPPTTTTPSPPITT--TTTPPPTTTPSSPITTTP------SPPTTTMTTPS 1700

Query: 962  PTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHA 1021
            PT +   P+ P    T P+   T P+  PT  T          PSPT T        P  
Sbjct: 1701 PTTT---PSSPITTTTTPS-STTTPSPPPTTMTT---------PSPTTT--------PSP 1739

Query: 1022 PSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLC 1070
            P+T MT+ +  TTT+S  +T   PP+    + + P S  +P   C PLC
Sbjct: 1740 PTTTMTT-LPPTTTSSPLTTTPLPPSITPPTFS-PFSTTTPTTPCVPLC 1786



 Score =  160 bits (404), Expect = 2e-38
 Identities = 147/446 (32%), Positives = 180/446 (40%), Gaps = 64/446 (14%)

Query: 548  VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTI 607
            +++  P  TT      + +T  PT +   P+ TT  P      P   T  P I+T     
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP------PPTTTPSPPITTTTTPP 1449

Query: 608  PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667
            P+  P+ P    T P   PT     PT     PT     PT +T  P  PT   TTP+  
Sbjct: 1450 PTTTPSPPISTTTTPP--PTTTPSPPTTTPSPPTTTPSPPTTTTTTPP-PT---TTPSPP 1503

Query: 668  TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIP 727
            TTT +  P   T  P  PT  PS PT         T  +T  PT +P  PT  T   T P
Sbjct: 1504 TTTPITPPASTTTLP--PTTTPSPPT---------TTTTTPPPTTTPSPPT--TTPITPP 1550

Query: 728  TEKSTISPEKPTTPTEKPTIPTEKP-TISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEK 786
            T  +T+ P   TTP+  PT  T  P T +P  PTT T  P             PTI T  
Sbjct: 1551 TSTTTLPPT--TTPSPPPTTTTTPPPTTTPSPPTTTTPSP-------------PTITTTT 1595

Query: 787  PTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIP 846
            P  PT  P+  T   TTP   TT     PS P   P  P   TTT    TT S    T  
Sbjct: 1596 PP-PTTTPSPPTTTTTTPPPTTT-----PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1649

Query: 847  MEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP 906
               PT +   PT  T  P I+       T     PT  P+ PI  TT S    T+ T  P
Sbjct: 1650 TPPPTTTPSPPTTTTPSPPIT-------TTTTPPPTTTPSSPI-TTTPSPPTTTMTTPSP 1701

Query: 907  TISPEKPTISTEKP---TIPTEKP---TIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
            T +P  P  +T  P   T P+  P   T P+  TT S    T+ T  PT +   LT    
Sbjct: 1702 TTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL 1761

Query: 961  KPTISTEKPTIPTEKLTIPTEKPTIP 986
             P+I+   PT      T PT  P +P
Sbjct: 1762 PPSIT--PPTFSPFSTTTPT-TPCVP 1784



 Score =  158 bits (399), Expect = 8e-38
 Identities = 174/599 (29%), Positives = 229/599 (38%), Gaps = 46/599 (7%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3439

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3500 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3615

Query: 705  ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
              T+ PT +P   T    PT  PT  T+  T +P   TT   PT  PT  T+ PT +P  
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3673

Query: 759  PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-I 817
             TT T  PT +P     PT  P I T     PT  PT +    TTP   TT  T  P+  
Sbjct: 3674 TTT-TVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3731

Query: 818  PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEK 877
              + PT     TTT+V  T   T   T      T +T     PT   T +P    I T  
Sbjct: 3732 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3791

Query: 878  LTIPTEKPTIPIEETT--ISTEKLTIPTEKPT--ISPEKPTISTEKPTIPTEKPTIPTEE 933
               PT  PT     TT  I+T     PT  PT   +P    I+T     PT  PT     
Sbjct: 3792 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3851

Query: 934  TT--ISTEKLTIPTEKPT---------ISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEK 982
            TT  I+T     PT  PT         I+      PT  PT +    T P    T  T  
Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3911

Query: 983  PTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            PT PT   T  T  +T      P+PT TG      +P   +T +T     T T + ++T
Sbjct: 3912 PT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3969



 Score =  158 bits (399), Expect = 8e-38
 Identities = 174/599 (29%), Positives = 229/599 (38%), Gaps = 46/599 (7%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3406 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3462

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3523 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3638

Query: 705  ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
              T+ PT +P   T    PT  PT  T+  T +P   TT   PT  PT  T+ PT +P  
Sbjct: 3639 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3696

Query: 759  PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-I 817
             TT T  PT +P     PT  P I T     PT  PT +    TTP   TT  T  P+  
Sbjct: 3697 TTT-TVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3754

Query: 818  PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEK 877
              + PT     TTT+V  T   T   T      T +T     PT   T +P    I T  
Sbjct: 3755 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814

Query: 878  LTIPTEKPTIPIEETT--ISTEKLTIPTEKPT--ISPEKPTISTEKPTIPTEKPTIPTEE 933
               PT  PT     TT  I+T     PT  PT   +P    I+T     PT  PT     
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3874

Query: 934  TT--ISTEKLTIPTEKPT---------ISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEK 982
            TT  I+T     PT  PT         I+      PT  PT +    T P    T  T  
Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3934

Query: 983  PTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            PT PT   T  T  +T      P+PT TG      +P   +T +T     T T + ++T
Sbjct: 3935 PT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3992



 Score =  158 bits (399), Expect = 8e-38
 Identities = 174/599 (29%), Positives = 229/599 (38%), Gaps = 46/599 (7%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3485

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3546 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3604

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3605 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3661

Query: 705  ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
              T+ PT +P   T    PT  PT  T+  T +P   TT   PT  PT  T+ PT +P  
Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3719

Query: 759  PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-I 817
             TT T  PT +P     PT  P I T     PT  PT +    TTP   TT  T  P+  
Sbjct: 3720 TTT-TVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3777

Query: 818  PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEK 877
              + PT     TTT+V  T   T   T      T +T     PT   T +P    I T  
Sbjct: 3778 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3837

Query: 878  LTIPTEKPTIPIEETT--ISTEKLTIPTEKPT--ISPEKPTISTEKPTIPTEKPTIPTEE 933
               PT  PT     TT  I+T     PT  PT   +P    I+T     PT  PT     
Sbjct: 3838 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3897

Query: 934  TT--ISTEKLTIPTEKPT---------ISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEK 982
            TT  I+T     PT  PT         I+      PT  PT +    T P    T  T  
Sbjct: 3898 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3957

Query: 983  PTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            PT PT   T  T  +T      P+PT TG      +P   +T +T     T T + ++T
Sbjct: 3958 PT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4015



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 1911 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 1967

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 1968 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2027

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2028 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2087 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2143

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2144 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2202 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2261

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2262 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2321

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2322 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2438

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 1934 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 1990

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 1991 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2050

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2051 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2166

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2167 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2284

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2285 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2344

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2345 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2404

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2461

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 1957 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2013

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2014 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2073

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2074 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2132

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2133 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2189

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2190 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2307

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2308 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2367

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2368 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2484

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 1980 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2036

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2037 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2096

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2097 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2156 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2212

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2213 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2330

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2331 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2390

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2391 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2507

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2003 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2059

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2119

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2120 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2235

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2236 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2353

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2354 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2413

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2414 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2530

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2026 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2082

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2083 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2142

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2143 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2202 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2258

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2259 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2376

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2377 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2436

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2437 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2496

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2553

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2105

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2106 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2165

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2166 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2281

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2282 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2399

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2400 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2459

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2460 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2576

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2072 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2128

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2129 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2188

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2189 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2304

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2305 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2422

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2423 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2482

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2599

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2151

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2152 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2211

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2212 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2327

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2328 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2505

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2506 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2565

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2622

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2118 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2174

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2175 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2234

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2235 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2350

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2351 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2468

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2469 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2528

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2529 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2588

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2645

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2141 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2197

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2198 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2257

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2258 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2373

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2374 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2491

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2492 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2551

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2552 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2668

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2164 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2220

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2221 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2280

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2281 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2396

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2397 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2514

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2515 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2574

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2575 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2634

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2691

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2187 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2243

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2244 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2303

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2304 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2419

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2420 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2537

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2538 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2597

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2598 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2714

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2266

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2267 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2326

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2327 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2442

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2443 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2560

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2561 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2620

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2621 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2737

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2233 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2289

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2350 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2465

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2466 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2584 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2643

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2644 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2760

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2256 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2312

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2372

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2373 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2488

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2489 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2546

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2606

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2607 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2666

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2667 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2783

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2279 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2335

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2396 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2511

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2512 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2629

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2630 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2689

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2690 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2806

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2302 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2358

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2419 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2534

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2535 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2652

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2653 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2712

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2713 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2772

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2829

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2381

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2442 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2557

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2558 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2675

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2676 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2735

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2736 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2852

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2348 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2404

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2465 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2580

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2581 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2698

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2699 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2758

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2759 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2818

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2875

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2427

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2488 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2546

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2603

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2604 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2721

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2722 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2781

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2782 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2841

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2898

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2394 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2450

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2511 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2626

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2627 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2684

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2744

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2745 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2804

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2921

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2473

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2534 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2649

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2650 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2767

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2768 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2827

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2828 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2944

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2496

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2557 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2672

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2673 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2790

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2850

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2851 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2910

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2967

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2519

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2580 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2695

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2696 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2873

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2990

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2542

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2603 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2718

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2719 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2836

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2837 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2896

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2897 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3013

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2565

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2626 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2684

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2741

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2742 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2859

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2860 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2919

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2920 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2979

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3036

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2532 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2588

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2649 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2764

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2765 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2882

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2883 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2942

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2943 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3059

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2611

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2672 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2787

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2788 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2906 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3082

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2578 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2634

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2695 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2810

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2811 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2928

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2929 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2988

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 2989 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3048

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3105

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2601 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2657

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2718 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2833

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2834 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2951

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2952 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3011

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3012 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3128

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2624 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2680

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2741 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2856

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2857 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2974

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2975 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3034

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3035 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3094

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3151

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2703

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2764 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2879

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2880 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2997

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 2998 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3057

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3058 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3117

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3174

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2670 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2726

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2787 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2902

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2903 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3080

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3081 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3197

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2749

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2810 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2925

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2926 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3043

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3103

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3104 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3220

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2772

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2833 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2948

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2949 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3066

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3067 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3126

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3243

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2795

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2856 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2971

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2972 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3149

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3150 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3266

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2762 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2818

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2879 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2994

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 2995 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3112

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3113 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3172

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3232

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3289

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2841

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2902 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3017

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3018 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3135

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3136 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3195

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3196 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3312

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2808 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2864

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2925 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3040

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3041 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3158

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3218

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3219 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3278

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3335

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2887

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2948 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3063

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3064 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3181

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3182 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3358

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2910

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2971 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3086

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3087 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3204

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3205 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3264

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3265 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3324

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3381

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2933

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 2994 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3109

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3110 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3227

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3228 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3287

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3404

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2956

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3017 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3132

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3133 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3250

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3251 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3310

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3311 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3427

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2979

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3040 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3155

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3156 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3333

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3334 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3393

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3450

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2946 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3002

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3063 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3178

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3179 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3296

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3297 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3356

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3357 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3473

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3474 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3025

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3086 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3201

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3202 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3319

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3320 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3379

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3380 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3439

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3496

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 2992 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3048

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3109 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3224

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3225 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3342

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3343 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3402

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3403 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3462

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3519

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3568



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3071

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3132 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3247

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3248 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3425

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3426 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3542

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3591



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3094

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3155 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3270

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3271 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3388

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3389 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3448

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3509 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3565

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3117

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3178 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3293

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3294 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3411

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3471

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3472 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3531

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3532 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3588

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3084 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3140

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3201 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3316

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3317 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3494

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3495 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3611

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3660



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3107 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3163

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3224 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3339

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3340 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3517

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3634

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3683



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3130 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3186

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3247 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3362

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3363 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3480

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3481 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3540

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3541 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3600

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3657

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3658 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3153 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3209

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3270 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3385

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3386 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3503

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3504 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3563

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3564 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3623

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3624 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3680

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3232

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3293 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3408

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3409 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3526

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3527 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3586

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3703

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3752



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3255

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3316 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3431

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3432 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3549

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3550 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3609

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3726

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3222 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3278

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3339 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3454

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3455 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3512

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3572

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3573 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3632

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3633 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3692

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3693 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3749

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3750 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3798



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3301

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3362 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3477

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3478 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3595

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3596 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3655

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3656 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3772

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3773 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3268 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3324

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3385 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3500

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3501 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3618

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3619 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3678

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3679 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3738

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3739 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3795

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3796 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3291 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3347

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3408 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3523

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3524 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3641

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3642 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3701

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3702 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3761

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3762 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3818

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3819 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3867



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3314 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3370

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3431 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3546

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3547 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3604

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3605 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3664

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3665 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3724

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3725 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3784

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3841

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3842 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3393

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3454 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3512

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3569

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3570 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3627

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3628 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3687

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3688 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3747

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3748 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3807

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3808 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3864

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3865 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913



 Score =  157 bits (396), Expect = 2e-37
 Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3416

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3477 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3592

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
              T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TTP T
Sbjct: 3593 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3650

Query: 764  EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
               T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+    
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3710

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
            + PT     TTT+V  T   T   T      T +T     PT   T +P    I T    
Sbjct: 3711 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3770

Query: 880  IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
             PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT     TT
Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830

Query: 936  --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
              I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T     P
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3887

Query: 994  TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            T   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 3888 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3936



 Score =  155 bits (393), Expect = 4e-37
 Identities = 163/546 (29%), Positives = 213/546 (39%), Gaps = 56/546 (10%)

Query: 531  PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEK 590
            P T P   +       P ++  P  +T  T  PT +   PT +   P+ T   PT     
Sbjct: 1434 PTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT 1493

Query: 591  PTIPTEKPTISTEKP-TIPSEKPNMPSEKPTIPSEKPTILTEKP---TIPSEKPTIPSEK 646
            P  PT  P+  T  P T P+    +P   PT     PT  T  P   T PS   T P   
Sbjct: 1494 PP-PTTTPSPPTTTPITPPASTTTLP---PTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1549

Query: 647  PTISTEKP--TVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            PT +T  P  T P+  PTT T    T+   P   T  PS PT   + P    T S   T 
Sbjct: 1550 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP-TTTTPSPPTITTTTPPPTTTPSPPTTT 1608

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP-TIPTEKPTISPEKPTTPT 763
             +T  PT +P  PT  T   T PT  +T+ P   TTP+  P T  T  PT +P  PTT T
Sbjct: 1609 TTTPPPTTTPSPPT--TTPITPPTSTTTLPP--TTTPSPPPTTTTTPPPTTTPSPPTTTT 1664

Query: 764  EKPTISPEKLTIPTEKPTIP-TEKPTIPTEKPTISTEEPTT------PTEETTISTEKPS 816
              P I+      PT  P+ P T  P+ PT   T++T  PTT       T  T  ST  PS
Sbjct: 1665 PSPPITTTTTPPPTTTPSSPITTTPSPPT--TTMTTPSPTTTPSSPITTTTTPSSTTTPS 1722

Query: 817  IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTE 876
             P    T P+  TT S   TT++T   T      T +   P+I    PT SP   T PT 
Sbjct: 1723 PPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSI--TPPTFSPFSTTTPT- 1779

Query: 877  KLTIPTEKPTIPIEETTISTEKLTIPTEKP---------TISPEKPTISTEKPTIPTEKP 927
                    P +P+   T   +       KP            P      + + T+  + P
Sbjct: 1780 -------TPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVP 1832

Query: 928  TIPTEETTISTEKLTI----PTEKP-TISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEK 982
                 +T +    + +      +KP  + P    +  E      E  T PT   T  TE 
Sbjct: 1833 IGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTEN 1892

Query: 983  PTIPTEKP------TIPTEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTT 1035
            PT PT  P        PT   T  + P  +P T T       +P    TP T+ I  TTT
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952

Query: 1036 TSRSST 1041
             + + T
Sbjct: 1953 VTPTPT 1958



 Score =  154 bits (389), Expect = 1e-36
 Identities = 164/545 (30%), Positives = 210/545 (38%), Gaps = 33/545 (6%)

Query: 521  VVAMGFIL---INPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKP 577
            V+ M F L   IN   C     P     +   +  P  TT +T   T++        + P
Sbjct: 1860 VIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTP 1919

Query: 578  S---VTTEKPTVPKEKPTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTE 631
            +   +TT     P   PT  T+ PT   I+T     P+  P       T P    T +T 
Sbjct: 1920 TTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1978

Query: 632  KPTIPSEKPTIPSEKPTISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688
             PT    +    +   T +T  PT     T+ PTT    TTT++     PT   + PT  
Sbjct: 1979 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTT 2037

Query: 689  PSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIP 748
            P   T   T++   T   T+ PT +P   T  T  PT PT   T +P      T     P
Sbjct: 2038 PITTTT--TVTPTPTPTGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTP 2093

Query: 749  TEKPTISPEKPTTP-TEKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTP 804
            T  PT +    TTP T   T++P      T+ PT   I T     PT  PT +    TTP
Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153

Query: 805  TEETTISTEKPS-IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEK 863
               TT  T  P+    + PT     TTT+V  T   T   T      T +T     PT  
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2213

Query: 864  PTISPEKLTIPTEKLTIPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEK 919
             T +P    I T     PT  PT     TT  I+T     PT  P  T +P    I+T  
Sbjct: 2214 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2273

Query: 920  PTIPTEKPTIPTEETT--ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLT 977
               PT  PT     TT  I+T     PT  PT +    T P    T  T  PT PT   T
Sbjct: 2274 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT 2332

Query: 978  IPTEKPTIPTEKPTIPTEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTT 1036
             PT  P I T     PT   T  + P  +P T T       +P    TP T+ I  TTT 
Sbjct: 2333 -PTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2390

Query: 1037 SRSST 1041
            + + T
Sbjct: 2391 TPTPT 2395



 Score =  154 bits (389), Expect = 1e-36
 Identities = 160/532 (30%), Positives = 206/532 (38%), Gaps = 30/532 (5%)

Query: 531  PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVP 587
            P T P+     + P    + T    TT +T   T++        + P+   +TT     P
Sbjct: 1896 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1955

Query: 588  KEKPTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPS 644
               PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +
Sbjct: 1956 TPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2014

Query: 645  EKPTISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME 701
               T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++  
Sbjct: 2015 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPT 2071

Query: 702  ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761
             T   T+ PT +P   T  T  PT PT   T +P      T     PT  PT +    TT
Sbjct: 2072 PTPTGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2129

Query: 762  P-TEKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS- 816
            P T   T++P      T+ PT   I T     PT  PT +    TTP   TT  T  P+ 
Sbjct: 2130 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2189

Query: 817  IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTE 876
               + PT     TTT+V  T   T   T      T +T     PT   T +P    I T 
Sbjct: 2190 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2249

Query: 877  KLTIPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTE 932
                PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT    
Sbjct: 2250 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2309

Query: 933  ETT--ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKP 990
             TT  I+T     PT  PT +    T P    T  T  PT PT   T PT  P I T   
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTT 2366

Query: 991  TIPTEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
              PT   T  + P  +P T T       +P    TP T+ I  TTT + + T
Sbjct: 2367 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418



 Score =  153 bits (387), Expect = 2e-36
 Identities = 137/428 (32%), Positives = 167/428 (39%), Gaps = 59/428 (13%)

Query: 544  PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS-VTTEKP--TVPKEKPTIPTEKPTI 600
            P  P ++  P  T+  T  PT +   PT +   P   TT  P  T     P   T  P I
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458

Query: 601  STEKPTIPSEKPNMPSEKPTIPS---EKPTILTEKP---TIPSEKPTIPSEKPTISTEKP 654
            ST     P+  P+ P+  P+ P+     PT  T  P   T PS   T P   P  +T  P
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518

Query: 655  TVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714
              PT  P+ PT  TTT       PT  PS PT  P  P          T  +T  PT +P
Sbjct: 1519 --PTTTPSPPTTTTTTPP-----PTTTPSPPTTTPITP---------PTSTTTLPPTTTP 1562

Query: 715  EKPTIPTEKPTIPTEKSTISPEKPTTPTEKP---TIPTEKPTISPEKPTTPTEKPTISPE 771
              P  PT   T  T   T +P  PTT T  P   T  T  PT +P  PTT     T +P 
Sbjct: 1563 SPP--PT---TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT----TTTTPP 1613

Query: 772  KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTT 831
              T P+   T P   PT  T  P  +T  P   T  T   T  PS P      P   TTT
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673

Query: 832  SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891
            +   TT  +  +T     PT      T+ T  PT +P            P    T P   
Sbjct: 1674 TPPPTTTPSSPITTTPSPPT-----TTMTTPSPTTTPSS----------PITTTTTPSST 1718

Query: 892  TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTIS 951
            TT S    T+ T  PT +P  PT      T+ T  PT  T  + ++T  L      PT S
Sbjct: 1719 TTPSPPPTTMTTPSPTTTPSPPT-----TTMTTLPPT--TTSSPLTTTPLPPSITPPTFS 1771

Query: 952  PEKLTIPT 959
            P   T PT
Sbjct: 1772 PFSTTTPT 1779



 Score =  152 bits (384), Expect = 4e-36
 Identities = 170/553 (30%), Positives = 212/553 (38%), Gaps = 37/553 (6%)

Query: 512  GIQGSNTASVVAMGFILINPGTCPVKVLP-------ELPPVSPVSSTGPSE-TTGLTENP 563
            G  G      V++G I  N    P  V+P       E+        T P+  TT  TENP
Sbjct: 1834 GQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENP 1893

Query: 564  TISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS 623
            T  T  P  +      TT  PT        PT  P I+T     P+  P       T P 
Sbjct: 1894 TPPTTTPITT-----TTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPI 1947

Query: 624  EKPTILTEKPTIPSEKPTIPSEKPTISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTE 680
               T +T  PT    +    +   T +T  PT     T+ PTT    TTT++     PT 
Sbjct: 1948 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2007

Query: 681  KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT 740
              + PT  P   T   T++   T   T+ PT +P   T  T  PT PT   T +P     
Sbjct: 2008 TQT-PTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPI 2062

Query: 741  PTEKPTIPTEKPTISPEKPTTP-TEKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTI 796
             T     PT  PT +    TTP T   T++P      T+ PT   I T     PT  PT 
Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2122

Query: 797  STEEPTTPTEETTISTEKPS-IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTE 855
            +    TTP   TT  T  P+    + PT     TTT+V  T   T   T      T +T 
Sbjct: 2123 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2182

Query: 856  KPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPE 911
                PT   T +P    I T     PT  PT     TT  I+T     PT  P  T +P 
Sbjct: 2183 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2242

Query: 912  KPTISTEKPTIPTEKPTIPTEETT--ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
               I+T     PT  PT     TT  I+T     PT  PT +    T P    T  T  P
Sbjct: 2243 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2302

Query: 970  TIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTS 1028
            T PT   T PT  P I T     PT   T  + P  +P T T       +P    TP T+
Sbjct: 2303 T-PTGTQT-PTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2359

Query: 1029 VILGTTTTSRSST 1041
             I  TTT + + T
Sbjct: 2360 PITTTTTVTPTPT 2372



 Score =  152 bits (384), Expect = 4e-36
 Identities = 187/663 (28%), Positives = 248/663 (37%), Gaps = 83/663 (12%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3669

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3730 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3788

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3789 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3845

Query: 705  ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
              T+ PT +P   T    PT  PT  T+  T +P   TT   PT  PT  T+ PT +P  
Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3903

Query: 759  PTT-----PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPT---ISTEEPTTPTEETTI 810
             TT     PT   T +P    I T     PT  PT  T+ PT   I+T    TPT   T 
Sbjct: 3904 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTG 3962

Query: 811  STEKPSIPMEKPT----LPTEETTTSVEETTISTEKLTIPMEKPT---------ISTEKP 857
            +    + P+   T     PT   T +   T I+T     P   PT         I+T   
Sbjct: 3963 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4022

Query: 858  TIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISP---EKPT 914
              PT  PT +    T P    T  T  PT    +T  +T   T  T  PT +P   + PT
Sbjct: 4023 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4082

Query: 915  ---ISTEKPTIPTEKPTIPTEETT--ISTEKLTIPTEKPT---------ISPEKLTIPTE 960
               I+T     PT  PT     TT  I+T     PT  PT         I+      PT 
Sbjct: 4083 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4142

Query: 961  KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATG--------- 1011
             PT +    T P    T  T  PT PT   T  T  +T      P+PT TG         
Sbjct: 4143 TPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHT 4201

Query: 1012 ----LAALVMS--PHAPSTPMTSVILGT-TTTSRSSTERCPPNARYESCACPASCKSPRP 1064
                +A L  S  P   STP TS    +  T S +     PP     S A P++  +P  
Sbjct: 4202 STAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTT 4261

Query: 1065 SCG 1067
            + G
Sbjct: 4262 TSG 4264



 Score =  151 bits (381), Expect = 1e-35
 Identities = 190/682 (27%), Positives = 257/682 (37%), Gaps = 69/682 (10%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3761

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    TT +T   T++        + P+   +TT     P   
Sbjct: 3762 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +    +   
Sbjct: 3822 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3880

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PTT    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 3881 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3937

Query: 705  ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
              T+ PT +P   T    PT  PT  T+  T +P   TT   PT  PT  T+ PT +P  
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3995

Query: 759  PTT---PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKP 815
             TT   PT  PT +    T P     I T     PT  PT +    TTP   TT  T  P
Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4050

Query: 816  S-IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIP 874
            +    + PT     TTT+V  T   T   T      T +T     PT   T +P    I 
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4110

Query: 875  TEKLTIPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIP 930
            T     PT  PT     TT  I+T     PT  P  T +P    I+T     PT  PT  
Sbjct: 4111 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4170

Query: 931  TEETT--ISTEKLTIPTEKPTIS-----PEKLTIPTEKPTISTEKPTIPTEKLTIPTEKP 983
               TT  I+T     PT  PT +         T P  + T S   P   T + +  T  P
Sbjct: 4171 QTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP 4230

Query: 984  TIPTEKPTI-----PTEKLTALRPPH--PSPTAT-GLAALVMSPHAPSTPMTSVILGTTT 1035
               TE  T+     P  ++T+  PP    +PT T G   L   P   ++P  +   GTTT
Sbjct: 4231 L--TESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTT 4288

Query: 1036 TSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNC 1095
             S S+    P  +  ++    A   +P P   P         P +  S   C       C
Sbjct: 4289 GSSSA----PTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP-YPSSVLIC-------C 4336

Query: 1096 FYNNDYYEPGAEWFSPNCTEHC 1117
              N+ YY PG E ++    + C
Sbjct: 4337 VLNDTYYAPGEEVYNGTYGDTC 4358



 Score =  147 bits (372), Expect = 1e-34
 Identities = 127/510 (24%), Positives = 197/510 (38%), Gaps = 54/510 (10%)

Query: 1032 GTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCRE----GCVCNPGFLFSD--- 1084
            G   T+    + CP N  Y     P            LC E    GC C  G ++ D   
Sbjct: 283  GNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGD 342

Query: 1085 NHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQ 1144
            + C+  S C+C  +   Y PG E    N  E C C                       G+
Sbjct: 343  SGCVPVSQCHCRLHGHLYTPGQE--ITNDCEQCVC---------------------NAGR 379

Query: 1145 YGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG 1204
            + C       TC + G  H  TFDG+ + F G C Y+LA+  G+  D +  +        
Sbjct: 380  WVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAK--GDHNDSYALLGELAPCGS 437

Query: 1205 QEGVSCLSKVYVTL--PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE 1262
             +  +CL  V +     ++ V        L+   QV LP + +       S   + +   
Sbjct: 438  TDKQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMA 497

Query: 1263 FGLR--VRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
             G+R  V+     QL+VT+     G++ GLCGN++G   +D     G          N+W
Sbjct: 498  IGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTW 557

Query: 1321 QTDQDEDQEC-QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFD 1379
            +        C  K   ++ P C  +++S+     +C  L  T  PF  C   V  A ++ 
Sbjct: 558  KA----QSSCHDKLDWLDDP-CSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYK 612

Query: 1380 SCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM---ACPPNSKYSLCA 1436
             C  D C  Q  +  LC  +S+    C   G  +  WRE H C     +CP +  +    
Sbjct: 613  RCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWRE-HVCNKDVGSCPNSQVFLYNL 671

Query: 1437 KPCPDTCHS-GFSGMFCSD--RCVEACEC-NPGFVLSGLECIPRSQCGCLHPAGSYFKVG 1492
              C  TC S   +   C +    V+ C C +  F+     C+P ++C C H  G Y + G
Sbjct: 672  TTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYH-RGLYLEAG 730

Query: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQ 1522
            +   +   +E CVC  + R+ C+  R   Q
Sbjct: 731  DVVVRQ--EERCVCR-DGRLHCRQIRLIGQ 757



 Score =  145 bits (366), Expect = 5e-34
 Identities = 173/611 (28%), Positives = 226/611 (36%), Gaps = 108/611 (17%)

Query: 531  PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKP-SVTTEKP---TV 586
            P T P+        + P ++  P  TT  T  PT +   PT +   P ++TT  P   T 
Sbjct: 1542 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTT 1601

Query: 587  PKEKPTIPTEKPTISTEKP--TIPSEKPNMPSEKP--TIPSEKPTILTEKP--TIPSEKP 640
            P    T  T  P  +T  P  T P   P   +  P  T PS  PT  T  P  T PS  P
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP-P 1660

Query: 641  TIPSEKPTISTEKPTVPTEEPTTPTEET----TTSMEEPVIPTEKPSIPTEKPSIPTEKP 696
            T  +  P I+T     PT  P++P   T    TT+M  P  PT  PS P    + P+   
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS-PTTTPSSPITTTTTPSSTT 1719

Query: 697  TISMEETIISTEKPTISPEKPT--IPTEKPTIPTEKSTISPEKP------------TTPT 742
            T S   T ++T  PT +P  PT  + T  PT  +   T +P  P            TTPT
Sbjct: 1720 TPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779

Query: 743  --------------------EKPTIPTE----------------KPTISPEKPTTPTEKP 766
                                 KP   TE                + T+ P+ P     + 
Sbjct: 1780 TPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQT 1839

Query: 767  TISPEKLTI----PTEKP--TIPT-------------EKPTIPTEKPTISTEEPTTPTEE 807
             +    + +      +KP   IP              E  T PT   T +TE PT PT  
Sbjct: 1840 VVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTT- 1898

Query: 808  TTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLT-IPMEKPT---ISTEKPTIPTEK 863
            T I+T     P   PT     TTT +  TT  T   T    + PT   I+T     PT  
Sbjct: 1899 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1958

Query: 864  PTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIP 923
            PT +    T P    T  T  PT    +T  +T   T  T  PT +P      T+ PT  
Sbjct: 1959 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTT- 2013

Query: 924  TEKPTIPTEETTISTEKLTIPTEKPTISPEKLTI---PTEKPTISTEKPTIPTEKLTIPT 980
                T  T  TT++       T+ PT +P   T    PT  PT +    T P    T  T
Sbjct: 2014 ----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2069

Query: 981  EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGT-----TT 1035
              PT PT   T  T  +T      P+PT TG      +P   +T +T     T     TT
Sbjct: 2070 PTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2128

Query: 1036 TSRSSTERCPP 1046
            T  ++T    P
Sbjct: 2129 TPITTTTTVTP 2139



 Score =  136 bits (342), Expect = 3e-31
 Identities = 158/532 (29%), Positives = 210/532 (39%), Gaps = 67/532 (12%)

Query: 529  INPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVS-IEKPSVTTEKPTVP 587
            I P      + P   P  P        TT  T  PT +   PT + I  P+ TT  P   
Sbjct: 1508 ITPPASTTTLPPTTTPSPPT-------TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT- 1559

Query: 588  KEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
                T P+  PT +T  P  P+  P+ P+   T PS  PTI T  P      PT     P
Sbjct: 1560 ----TTPSPPPTTTTTPP--PTTTPSPPT--TTTPS-PPTITTTTP-----PPTTTPSPP 1605

Query: 648  TISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIST 707
            T +T  P  PT   TTP+  TTT +  P   T  P  PT  PS P          T  +T
Sbjct: 1606 TTTTTTPP-PT---TTPSPPTTTPITPPTSTTTLP--PTTTPSPP---------PTTTTT 1650

Query: 708  EKPTISPEKPTIPTEKPTIPTEKS---TISPEKPTTPTEKP---TIPTEKPTISPEKP-- 759
              PT +P  PT  T  P I T  +   T +P  P T T  P   T+ T  PT +P  P  
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710

Query: 760  --TTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSI 817
              TTP+   T SP   T+ T  PT     PT      T++T  PTT +   T +   PSI
Sbjct: 1711 TTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT-----TTMTTLPPTTTSSPLTTTPLPPSI 1765

Query: 818  PMEKPTL-PTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTE--KPTISPEKLTIP 874
                PT  P   TT +     +      +   KP     KP   TE       P      
Sbjct: 1766 --TPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNF--HKPGGDTELIGDVCGPGWAANI 1821

Query: 875  TEKLTIPTEKPTIPIEETTISTEKLTI----PTEKP-TISPEKPTISTEKPTIPTEKPTI 929
            + + T+  + P   + +T +    + +      +KP  + P    ++ E      E  T 
Sbjct: 1822 SCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQ 1881

Query: 930  PTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEK 989
            PT  TT +TE  T PT  P  +   +T PT  PT +    T P    T  T  PT PT  
Sbjct: 1882 PTTMTTTTTENPTPPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPT-PTGT 1939

Query: 990  PTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
             T  T  +T      P+PT TG      +P   +T +T     T T + ++T
Sbjct: 1940 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1991



 Score =  128 bits (321), Expect = 9e-29
 Identities = 119/455 (26%), Positives = 171/455 (37%), Gaps = 52/455 (11%)

Query: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY--------GC--HAQGAATC 1542
            E W+   C  +  C+ NN +      C         +G+         GC  H +    C
Sbjct: 4423 ETWWLCDCF-MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYC 4481

Query: 1543 TASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFV--------------VSATNE 1588
            T  GDPHY+TFDG  + + G CTYVL     S S D++ V                 T  
Sbjct: 4482 TGWGDPHYVTFDGLYYSYQGNCTYVLVEEI-SPSVDNFGVYIDNYHCDPNDKVSCPRTLI 4540

Query: 1589 NRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648
             R    EV  IK VH+    +        +V +N   VALP +   G    +   N V+ 
Sbjct: 4541 VRHETQEV-LIKTVHMMPMQV--------QVQVNRQAVALP-YKKYGLEVYQSGINYVVD 4590

Query: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
                G+ V Y+G           +G    G CG   N + DD + P  ++  +       
Sbjct: 4591 IPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQ 4650

Query: 1709 WKLPESSEPGC---FLVGGKPSSCQENSMADAWNKNCA----ILINPQGPFSQCHQVVPP 1761
            W + + S+P C        +P+           +K+C       +     F+QCH +VPP
Sbjct: 4651 WLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPP 4710

Query: 1762 QSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTF--CPMRCPPGSSYS 1819
            Q  + +CV   C   G +   C SLQAYA+LCAQ      WRN T   C + CP    Y 
Sbjct: 4711 QHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQ 4769

Query: 1820 PCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHP 1878
             C      TC S ++ ++        E C C +G +       V +  CGC  P      
Sbjct: 4770 ACGPAEEPTCKSSSSQQN---NTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 4826

Query: 1879 VGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913
             GE +  E  C         + I C    C    +
Sbjct: 4827 FGEHF--EFDCKNCVCLEGGSGIICQPKRCSQKPV 4859



 Score =  100 bits (250), Expect = 1e-20
 Identities = 113/488 (23%), Positives = 184/488 (37%), Gaps = 68/488 (13%)

Query: 1892 LCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP----------GESHYVS 1941
            + TC  +N +   +  C+P  +    +GL   R      C             G+ HYV+
Sbjct: 4432 MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVT 4491

Query: 1942 FDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH----EKEEGGTEAFRLHEVYIDIYD 1997
            FDG  +S    CT VLV+   P++      I   H    +K          HE    +  
Sbjct: 4492 FDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIK 4551

Query: 1998 AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI-KIGVQVKFDGNHLLEIE 2056
                +    +V +N + V LP      G+ V  S I  +V+I ++GV V ++G     + 
Sbjct: 4552 TVHMMPMQVQVQVNRQAVALPYKKY--GLEVYQSGINYVVDIPELGVLVSYNGLS-FSVR 4608

Query: 2057 IPTTYYG-KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD-IDPSCQSLLVDE 2114
            +P   +G    G CG   +   D+ ++PS E+ ++     + W   D   P C       
Sbjct: 4609 LPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTT 4668

Query: 2115 QQ----IPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL 2170
            ++    +P   +  P  +C  + L      C+  ++  ++AQC + +    +   C    
Sbjct: 4669 KRPAVTVPGGGKTTPHKDCTPSPL------CQ-LIKDSLFAQCHALVPPQHYYDACVFDS 4721

Query: 2171 CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF--CPLECPAYSSYTNCLPSCSPSC 2228
            C   G     C +LQA+ A C  Q +    WRN +   C +ECP++  Y  C P+  P+C
Sbjct: 4722 CFMPG-SSLECASLQAYAALCAQQNICLD-WRNHTHGACLVECPSHREYQACGPAEEPTC 4779

Query: 2229 WDLDGRCEGAKVPSACAEGCICQPG---YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVS 2285
                 +       +   EGC C  G   Y    D CV    CGC          G+ +  
Sbjct: 4780 KSSSSQQNN----TVLVEGCFCPEGTMNYAPGFDVCV--KTCGCVGPDNVPREFGEHFEF 4833

Query: 2286 SGCTEKCVCT--GGAIQCGDFRC--------------------PSGSHCQLTSDNSNSNC 2323
                + CVC   G  I C   RC                    P+ + C +T    N++ 
Sbjct: 4834 D--CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSL 4891

Query: 2324 VSDKSEQC 2331
              +K   C
Sbjct: 4892 CKEKPSVC 4899



 Score = 95.1 bits (235), Expect = 8e-19
 Identities = 80/294 (27%), Positives = 126/294 (42%), Gaps = 29/294 (9%)

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIK----TVDVLPEGVEPLLVEGRNKMDPPRSSI 2386
            C+ +GDP Y+TFDG  Y  QG  TYVL++    +VD     ++    +  +K+  PR+ I
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 4540

Query: 2387 FLQE----VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYL-VTDFE 2441
               E    +I TV+   +Q+Q    + VN Q +A+PY+    L V   G    + + +  
Sbjct: 4541 VRHETQEVLIKTVHMMPMQVQ----VQVNRQAVALPYK-KYGLEVYQSGINYVVDIPELG 4595

Query: 2442 LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKT 2501
            ++VS+ G   +V      +     G CG       +D +LPSG +  N     + W V  
Sbjct: 4596 VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV-N 4654

Query: 2502 EDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACH 2561
            + +    P +    +       G        +C+P  L       C+++ D    FA CH
Sbjct: 4655 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL-------CQLIKD--SLFAQCH 4705

Query: 2562 QTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRT 2615
              V P+ + + CV D C          L C  L  YA LC +    L  WR+ T
Sbjct: 4706 ALVPPQHYYDACVFDSCFMPG----SSLECASLQAYAALCAQQNICL-DWRNHT 4754



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 49/155 (31%), Positives = 62/155 (40%), Gaps = 13/155 (8%)

Query: 902  PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE-KLTIPTE 960
            P +K   +P  PT +   P  PT   T+P   TT S    T  T  PT +P   +T  T 
Sbjct: 1391 PMDKCITTPSPPTTTPSPP--PTSTTTLP-PTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447

Query: 961  KPTISTEKPTIPTEKLTIPTEKPTIPTEKP----TIPTEKLTALRPPHPS-----PTATG 1011
             P  +T  P I T     PT  P+ PT  P    T P+   T    P P+     PT T 
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 1012 LAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPP 1046
            +     +   P T   S    TTTT   +T   PP
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542



 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 74/334 (22%), Positives = 120/334 (35%), Gaps = 47/334 (14%)

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
            CS +G+  Y TFDG  +R  G   Y          +     L  G  + + P     ++ 
Sbjct: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAG---VES 93

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVP-YRPNEHLRVTLWGQRLYLVTDFELVVSFGGR 2449
            ++ T+    + L   L  V+N   ++ P Y P   +  +    ++Y      L+ +   R
Sbjct: 94   ILLTIKDDTIYLTRHLA-VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWN---R 149

Query: 2450 KNAV-ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
            ++A+ + L + +     GLCG+Y+  +     L  G L   L  FGN  ++   D +   
Sbjct: 150  EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCED 208

Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEP 2568
            P                       E +P   + +  +  R+L      FA C   V  EP
Sbjct: 209  PE---------------------EEVAPASCSEHRAECERLLTAEA--FADCQDLVPLEP 245

Query: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQN---- 2624
            +   C  D C        +   C  ++ ++  C  AG     WR  TLC   C  N    
Sbjct: 246  YLRACQQDRCRCPGG---DTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYL 302

Query: 2625 ----PCQNDGQCREQGATFTCECEVGYGGGLCME 2654
                PC +   C     +  CE E    G  C E
Sbjct: 303  ESGSPCMD--TCSHLEVSSLCE-EHRMDGCFCPE 333


>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 593

 Score =  297 bits (760), Expect = 1e-79
 Identities = 182/547 (33%), Positives = 254/547 (46%), Gaps = 77/547 (14%)

Query: 1240 LPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNS 1298
            LP + + G    +  G  V ++T+FGLRV +D    + VTV   Y  ++CGLCGNY+G+ 
Sbjct: 3    LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62

Query: 1299 DNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ--------KYQVVNSPSCDSSLQSSMS 1350
             +D  K +GS AG+  E GNSW+ +   D  C             + S  C   L+    
Sbjct: 63   KDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121

Query: 1351 GPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAG 1410
               FCG L    GP  +C   V        C+ D+C   G   +LC+++    + CQ AG
Sbjct: 122  KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181

Query: 1411 HAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSG 1470
              V+PWR   FCPM CPPNS Y LCA  C   C +  +   C D C E C+C+ GF+ +G
Sbjct: 182  GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241

Query: 1471 LECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDG 1530
              C+P  QCGC H  G Y++  +      C++ C C +   + CQ   C+  + C    G
Sbjct: 242  QACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300

Query: 1531 IYGC--------------HAQGAA-----------------------------TCTASG- 1546
            I  C                +GAA                             TC   G 
Sbjct: 301  ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360

Query: 1547 ----------------DPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATN 1587
                            DPHY +FDG    F GTC YVL     P  S    + F V+  N
Sbjct: 361  QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420

Query: 1588 ENRGGILEVSYIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNL 1645
            +NRG    VSY++ V V     +IS+ +    KV +NG   ALPV +A GR+++   ++ 
Sbjct: 421  QNRGN-PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASK 479

Query: 1646 VLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQL 1705
             LL  +FGLQV YD +  V+VT+PSSY G +CGLCGN + N  +D + P+  LA      
Sbjct: 480  ALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIW 539

Query: 1706 GAAWKLP 1712
            G +W+ P
Sbjct: 540  GGSWRAP 546



 Score =  266 bits (679), Expect = 3e-70
 Identities = 162/558 (29%), Positives = 249/558 (44%), Gaps = 86/558 (15%)

Query: 1628 LPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNS 1687
            LPV LA G++      + V++ T+FGL+V YD  + V VTVP +Y  Q+CGLCGNYN + 
Sbjct: 3    LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62

Query: 1688 LDDNLRPDRKLAGDSMQLGAAWK--LPES-------SEPG---CFLVGGKPSSCQENSMA 1735
             DD  +P+   AG++ + G +W+  +P+S         PG   C      P   ++    
Sbjct: 63   KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQK 122

Query: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC-A 1794
            + +   C +L +P GP S CH++V PQ     C+   C   G+ + LC ++ AY S C A
Sbjct: 123  EEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179

Query: 1795 QAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGH 1854
              G    WR  TFCPM CPP S Y  C+  C   CS+++ P  C     CAE C+C  G 
Sbjct: 180  AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--CAEGCQCDSGF 237

Query: 1855 ILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQIC 1914
            + +G +CVP+ QCGC      Y P  E+    + C + CTC     + C + +CKP Q+C
Sbjct: 238  LYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVC 295

Query: 1915 WALDGLLRC--------------------------------------------------- 1923
                G+L C                                                   
Sbjct: 296  QPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETC 355

Query: 1924 -RASGVGVC--------QLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFK 1971
                G GVC         L G+ HY SFDG        C  VL     P ++   L  F 
Sbjct: 356  KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415

Query: 1972 ISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVK 2029
            ++ K++   G      +  V +      +++ K    +V +N     LP       +SV 
Sbjct: 416  VTTKNQ-NRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474

Query: 2030 SSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVAN 2089
              +  +++    G+QV +D N  +++ +P++Y+G VCG+CGN +    ++ + P+  +A 
Sbjct: 475  QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534

Query: 2090 SDSEFVNSWKDKDIDPSC 2107
            S   +  SW+    DP C
Sbjct: 535  SIPIWGGSWRAPGWDPLC 552



 Score =  202 bits (515), Expect = 3e-51
 Identities = 148/541 (27%), Positives = 223/541 (41%), Gaps = 82/541 (15%)

Query: 2036 IVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFV 2095
            ++    G++V +D  + + + +P  YY ++CG+CGN+N + +D+   P+   A + +EF 
Sbjct: 22   VIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG 81

Query: 2096 NSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVW--A 2151
            NSW++   D  C   L      P  +   PS  C   +L +  +K E    L +P    +
Sbjct: 82   NSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC-PPELEKKYQKEEFCGLLSSPTGPLS 137

Query: 2152 QCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLEC 2211
             C   +D    L DC   LC  GG    LC  + A+ + CQ+ G     WR  +FCP+EC
Sbjct: 138  SCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197

Query: 2212 PAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGC 2269
            P  S Y  C  +CS  C  L    +C+       CAEGC C  G++ +   CVP  QCGC
Sbjct: 198  PPNSHYELCADTCSLGCSALSAPPQCQ-----DGCAEGCQCDSGFLYNGQACVPIQQCGC 252

Query: 2270 KD---------------------AHGGSIPL--------GKSWVSSGCTEKCVCT----- 2295
                                    H G + +        G+    SG    CV       
Sbjct: 253  YHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRS 312

Query: 2296 ---------GGAI-----------------QCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
                     G AI                  C    C     C+         C+ +   
Sbjct: 313  LAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCK--EQGGQGVCLPNYEA 370

Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIF 2387
             C ++GDP Y +FDG  +  QG   YVL  T    V  +G+ P  V  +N+     +  +
Sbjct: 371  TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSY 430

Query: 2388 LQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVV 2444
            ++ V     G  + +      ++ VN    A+P    +  + VT    +  LV DF L V
Sbjct: 431  VRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQV 490

Query: 2445 SFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDA 2504
            S+       ++LPS Y G V GLCGN D+N  ND + P+G L  ++  +G SW     D 
Sbjct: 491  SYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 550

Query: 2505 L 2505
            L
Sbjct: 551  L 551



 Score =  151 bits (382), Expect = 7e-36
 Identities = 112/352 (31%), Positives = 149/352 (42%), Gaps = 78/352 (22%)

Query: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
            CPPN+ YE CA  C   C   S  P C   C EGC C+ GFL++   C+    C C++N 
Sbjct: 197  CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 256

Query: 1100 DYYEPGAEWFSPN--------------CTEHCRCWPGSRVE------------------- 1126
             YYEP       N              C EH  C PG   +                   
Sbjct: 257  VYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHS-CKPGQVCQPSGGILSCVTKVTLRSLAQ 315

Query: 1127 ----------------------------CQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
                                        C    C     C+ + GQ  C P    ATC +
Sbjct: 316  TGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNY-EATCWL 374

Query: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDPF--FRVTAKNEEQGQEGVSCLSKV 1214
            +GDPHY +FDGR F F G C Y+LA   C G ST     F VT KN+ +G   VS +  V
Sbjct: 375  WGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVV 434

Query: 1215 YVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG---VFLGASGRFVELQTEFGLRVRW 1269
             V    + +++ K    +  V G    LP   + G   V  GAS     L  +FGL+V +
Sbjct: 435  TVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKAL--LVADFGLQVSY 492

Query: 1270 DGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQ 1321
            D + ++ VT+ S+Y G +CGLCGN D N +ND +  +G+ A      G SW+
Sbjct: 493  DWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544



 Score =  104 bits (259), Expect = 1e-21
 Identities = 70/250 (28%), Positives = 107/250 (42%), Gaps = 31/250 (12%)

Query: 2422 NEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMML 2481
            N  +R +  G  + + TDF L V++       +++P  Y   + GLCGNY+ + K+D   
Sbjct: 9    NGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQK 68

Query: 2482 PSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLA 2540
            P+G+   N N FGNSWE    D+    P   P          G    +   +C PE +  
Sbjct: 69   PNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPP---------GSEDCIPSHKCPPELEKK 119

Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600
                + C +L+ P GP ++CH+ V P+   + C+ DLC          + C  +  Y   
Sbjct: 120  YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG---NLSILCSNIHAYVSA 176

Query: 2601 CQEAGAALAGWRDRTLCESPCLQNP----CQN-----------DGQCREQGATFTCECEV 2645
            CQ AG  +  WR  T C   C  N     C +             QC++ G    C+C+ 
Sbjct: 177  CQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD-GCAEGCQCDS 235

Query: 2646 G--YGGGLCM 2653
            G  Y G  C+
Sbjct: 236  GFLYNGQACV 245


>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
          Length = 2813

 Score =  290 bits (743), Expect = 1e-77
 Identities = 222/801 (27%), Positives = 329/801 (41%), Gaps = 88/801 (10%)

Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQ 1205
            G    + TA C ++G     TFDG  + F G C+Y+LA  C   +   F +        Q
Sbjct: 25   GTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS---FSIIG----DFQ 77

Query: 1206 EGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE-FG 1264
             G      VY+         + G  T  G Q+V++P   SKG++L     + +L  E +G
Sbjct: 78   NGKRVSLSVYLGEFFDIHLFVNGTVTQ-GDQRVSMP-YASKGLYLETEAGYYKLSGEAYG 135

Query: 1265 LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQ 1324
               R DG     V +S  Y  K CGLCGN++  +++D +  +G+   D  +  NSW    
Sbjct: 136  FVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS 195

Query: 1325 DEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLD 1384
             E Q C++    +S SC+ S      G     +L+ +   F  C   V    F   C   
Sbjct: 196  GE-QWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKT 253

Query: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
            +C   G     C  +     TC   G  +  W +   C   CP   +Y  C  PC  TC 
Sbjct: 254  LCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQ 313

Query: 1445 SGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCK--- 1501
            S      C +RCV+ C C  G +L    C+  ++C C+H        G+R Y PG     
Sbjct: 314  SLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHS-------GKR-YPPGTSLSR 365

Query: 1502 --ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHH 1559
                C+C ++       W C  +E  G+              C  +G  H+ +FD     
Sbjct: 366  DCNTCICRNSQ------WICSNEECPGE--------------CLVTGQSHFKSFDNRYFT 405

Query: 1560 FMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLR---G 1616
            F G C Y+L R C    QD  F +           +    ++V V +  L  SL++   G
Sbjct: 406  FSGICQYLLARDC----QDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHG 461

Query: 1617 CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQL 1676
              V ++G  V LP+     R+   +++++ L Y    LQ+ +DG   + V +   Y G+ 
Sbjct: 462  AGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGE-DLQMDWDGRGRLLVKLSPVYAGKT 520

Query: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMAD 1736
            CGLCGNYN N  DD L P           G AWKL    +    L       C  N    
Sbjct: 521  CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQD---LQKQHSDPCALNPRMT 577

Query: 1737 AWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
             +++  CA+L +P   F  CH+ V P     +C +  C        LC +L +YA+ CA 
Sbjct: 578  RFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635

Query: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNP-RDCPKALPCAESCECQKG- 1853
             G   AWR    C + CP G  Y  C +PC  TC S++ P  +C +A  C E C C  G 
Sbjct: 636  RGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEA--CLEGCFCPPGL 693

Query: 1854 HILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913
            ++     CVP  QC C      + P  E  ++++                       + +
Sbjct: 694  YMDERGDCVPKAQCPCYYDGEIFQP--EDIFSDH-----------------------HTM 728

Query: 1914 CWALDGLLRCRASGVGVCQLP 1934
            C+  DG + C  SGV    LP
Sbjct: 729  CYCEDGFMHCTMSGVPGSLLP 749



 Score =  263 bits (673), Expect = 1e-69
 Identities = 210/777 (27%), Positives = 324/777 (41%), Gaps = 86/777 (11%)

Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
            A C+  G     TFDG+++ F G C+Y+L   C  RS       S   + + G       
Sbjct: 33   ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS------FSIIGDFQNG------- 79

Query: 1600 KAVHVTVF---DLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
            K V ++V+      I L     V     RV++P + ++G      +    L    +G   
Sbjct: 80   KRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMP-YASKGLYLETEAGYYKLSGEAYGFVA 138

Query: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSE 1716
            R DGS   +V +   Y  + CGLCGN+N  + DD +  +  L  D      +W L  S E
Sbjct: 139  RIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWAL-SSGE 197

Query: 1717 PGCFLVGGKPSSCQENS--MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
              C       SSC  +S  M     + C +L      F++CH +V P+   A C    C 
Sbjct: 198  QWCERASPPSSSCNISSGEMQKGLWEQCQLL-KSTSVFARCHPLVDPEPFVALCEKTLCE 256

Query: 1775 TKGDTTALCRSLQAYASLCAQAGQAP-AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
              G     C +L  YA  CAQ G     W + + C   CP G  Y  C SPC  TC S++
Sbjct: 257  CAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLH 316

Query: 1834 NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
                C +   C + C C +G +L    CV   +C C          G+R+    + +R C
Sbjct: 317  INEMCQER--CVDGCSCPEGQLLDEGLCVESTECPCVHS-------GKRYPPGTSLSRDC 367

Query: 1894 -TCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
             TC   N+    Q  C  N+ C              G C + G+SH+ SFD    +    
Sbjct: 368  NTCICRNS----QWICS-NEEC-------------PGECLVTGQSHFKSFDNRYFTFSGI 409

Query: 1953 CTLVLVKVCHP-AMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
            C  +L + C   + ++    +    +++   T +  +      ++++ V L+ G  V ++
Sbjct: 410  CQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVTVR--LPGLHNSLVKLKHGAGVAMD 467

Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIG--VQVKFDGNHLLEIEIPTTYYGKVCGMC 2069
             + V LP +    G      ++ + V +  G  +Q+ +DG   L +++   Y GK CG+C
Sbjct: 468  GQDVQLPLLK---GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLC 524

Query: 2070 GNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNC 2129
            GN+N  + D+ + PS        +F N+WK   +   CQ L           Q+  S  C
Sbjct: 525  GNYNGNQGDDFLTPSGLAEPRVEDFGNAWK---LHGDCQDL-----------QKQHSDPC 570

Query: 2130 RAAD-LRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFG 2188
                 + R  E+  A L +P +  C   +   P+L +C   +C      + LC AL ++ 
Sbjct: 571  ALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYA 630

Query: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL---DGRCEGAKVPSACA 2245
            A C  +G++   WR    C L CP    Y  C   C+ +C  L   D  C       AC 
Sbjct: 631  AACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECN-----EACL 684

Query: 2246 EGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301
            EGC C PG  + E   CVP++QC C   + G I   +   S   T  C C  G + C
Sbjct: 685  EGCFCPPGLYMDERGDCVPKAQCPC--YYDGEIFQPEDIFSDHHT-MCYCEDGFMHC 738



 Score =  220 bits (561), Expect = 1e-56
 Identities = 177/705 (25%), Positives = 289/705 (40%), Gaps = 91/705 (12%)

Query: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
            S    C L G     +FDGS +S    C+ +L   C        F I    +  +  + +
Sbjct: 30   SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGDFQNGKRVSLS 85

Query: 1986 FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSS-IYSIVNIKIGVQ 2044
              L E + DI+     L     V    ++V++P  S+  G+ +++ +  Y +     G  
Sbjct: 86   VYLGE-FFDIH-----LFVNGTVTQGDQRVSMPYASK--GLYLETEAGYYKLSGEAYGFV 137

Query: 2045 VKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID 2104
             + DG+   ++ +   Y+ K CG+CGNFN   ED+ M     + +   +F NSW     +
Sbjct: 138  ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197

Query: 2105 PSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAR---EKCEAALRAPVWAQCASRIDLTP 2161
              C            E+   PS +C  +     +   E+C+      V+A+C   +D  P
Sbjct: 198  QWC------------ERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEP 245

Query: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
            F+  C  TLCE  G  +  C AL  +  TC  +G+    W + S C   CPA   Y  C+
Sbjct: 246  FVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCV 305

Query: 2222 PSCSPSCWDL--DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL 2279
              C+ +C  L  +  C+       C +GC C  G +L E  CV  ++C C  + G   P 
Sbjct: 306  SPCARTCQSLHINEMCQ-----ERCVDGCSCPEGQLLDEGLCVESTECPCVHS-GKRYPP 359

Query: 2280 GKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
            G S +S  C   C+C      C +  CP                      +C V G   +
Sbjct: 360  GTS-LSRDC-NTCICRNSQWICSNEECPG---------------------ECLVTGQSHF 396

Query: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYK 2399
             +FD   +   G   Y+L +      +    +++E     D  R ++  + V   + G  
Sbjct: 397  KSFDNRYFTFSGICQYLLARDCQ---DHSFSIVIETVQCAD-DRDAVCTRSVTVRLPGLH 452

Query: 2400 ---VQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISL 2456
               V+L+ G  + ++ Q + +P    +          + L    +L + + GR   ++ L
Sbjct: 453  NSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKL 512

Query: 2457 PSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEE 2516
              +Y G   GLCGNY+ N+ +D + PSG     +  FGN+W++  +   L+   + P   
Sbjct: 513  SPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPC-- 570

Query: 2517 EGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLD 2576
                                 ++   S +AC VL  P   F ACH+ V+P P+  +C  D
Sbjct: 571  -----------------ALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYD 611

Query: 2577 LCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            +CS  D R   E  C  L+ YA  C   G  +A WR+   CE  C
Sbjct: 612  VCSCSDGR---ECLCGALASYAAACAGRGVRVA-WREPGRCELNC 652



 Score =  208 bits (529), Expect = 7e-53
 Identities = 144/506 (28%), Positives = 209/506 (41%), Gaps = 45/506 (8%)

Query: 990  PTIPTEKLTALRPPHPSPTATGL--AALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPN 1047
            P +  E   AL        A GL  A   +  +A +     ++L   T   + +  CP  
Sbjct: 239  PLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAG 298

Query: 1048 ARYESCA--CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYE 1103
              Y  C   C  +C+S   +  C   C +GC C  G L  +  C++++ C C ++   Y 
Sbjct: 299  MEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP 358

Query: 1104 PGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPH 1163
            PG    S +C                        C  +N Q+ C        CLV G  H
Sbjct: 359  PGTS-LSRDCN----------------------TCICRNSQWICSNEECPGECLVTGQSH 395

Query: 1164 YVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQE-GVSCLSKVYVTLP--- 1219
            + +FD R+F F G C Y+LA+ C    D  F +  +  +   +    C   V V LP   
Sbjct: 396  FKSFDNRYFTFSGICQYLLARDC---QDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLH 452

Query: 1220 ESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTV 1279
             S V L  G    + GQ V LP +             V L     L++ WDG  +L V +
Sbjct: 453  NSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKL 512

Query: 1280 SSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSP 1339
            S  Y+GK CGLCGNY+GN  +D L   G      E+ GN+W+   D    CQ  Q  +S 
Sbjct: 513  SPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGD----CQDLQKQHSD 568

Query: 1340 SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHM 1399
             C  + + +      C  L  T   FE C   V    +  +C  D+C     +  LC  +
Sbjct: 569  PCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGAL 626

Query: 1400 STMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHS-GFSGMFCSDRCVE 1458
            ++    C   G  V  WREP  C + CP    Y  C  PC  TC S  +    C++ C+E
Sbjct: 627  ASYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLE 685

Query: 1459 ACECNPGFVLSGL-ECIPRSQCGCLH 1483
             C C PG  +    +C+P++QC C +
Sbjct: 686  GCFCPPGLYMDERGDCVPKAQCPCYY 711



 Score =  175 bits (444), Expect = 5e-43
 Identities = 125/470 (26%), Positives = 189/470 (40%), Gaps = 53/470 (11%)

Query: 1044 CPP-NARYESCACPASCKSPRPSCGPL-CREGCVCNPGFLFSDNHCIQASSCNCFYNNDY 1101
            CP  N R E   C  +C++    C  + C  GC+C PG +  +N C+    C CF+    
Sbjct: 776  CPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKE 835

Query: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGD 1161
            Y PG                      +  + G +T C  ++ ++ C  +   ATC   G 
Sbjct: 836  YAPG----------------------ETVKIGCNT-CVCRDRKWNCTDHVCDATCSTIGM 872

Query: 1162 PHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPES 1221
             HY+TFDG  + F G+C Y+L Q    S    FR+   N+      V C  +V + +   
Sbjct: 873  AHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGG 932

Query: 1222 TVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSS 1281
             + L  G         V  P        +  SGR++ L     L V WD    + V +  
Sbjct: 933  EIELFDGE------VNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQ 986

Query: 1282 TYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSP-S 1340
            TY  K+CGLCGN+DG  +ND    +     D  + GNSW+    +  + +K  + +SP +
Sbjct: 987  TYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-SSQCADTRKVPLDSSPAT 1045

Query: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQH--LLCTH 1398
            C +++         C  L  T   F+ C   V    + D C+ D C  + +      C  
Sbjct: 1046 CHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDT 1103

Query: 1399 MSTMTTTCQDAGHAVKPWREPHFCPMACPPNS----------KYSLCAKPCPDTCHSGFS 1448
            ++     C   G  V  WR    CP +C   +          +Y+ CA  C  TC     
Sbjct: 1104 IAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHP-E 1161

Query: 1449 GMFCSDRCVEAC--ECNPGFVLSGL--ECIPRSQCGCLHPAGSYFKVGER 1494
             + C  +CVE C   C PG +L  L   C+    C     AG  F  G++
Sbjct: 1162 PLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKK 1211



 Score =  150 bits (378), Expect = 2e-35
 Identities = 130/515 (25%), Positives = 209/515 (40%), Gaps = 79/515 (15%)

Query: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ 1478
            P    + CP ++  +   + C  TC + +     S  CV  C C PG V     C+   +
Sbjct: 769  PPMVKLVCPADNLRAEGLE-CTKTCQN-YDLECMSMGCVSGCLCPPGMVRHENRCVALER 826

Query: 1479 CGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQG 1538
            C C H  G  +  GE   K GC   CVC      R + W C     C             
Sbjct: 827  CPCFHQ-GKEYAPGET-VKIGCNT-CVC------RDRKWNC-TDHVCD------------ 864

Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVV---------SATNEN 1589
             ATC+  G  HYLTFDG  + F G C YVL +     +  ++ ++         S   + 
Sbjct: 865  -ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKK 923

Query: 1590 RGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLY 1649
            R  IL    ++   + +FD  +++ R  K               +    +  S   ++L 
Sbjct: 924  RVTIL----VEGGEIELFDGEVNVKRPMK--------------DETHFEVVESGRYIILL 965

Query: 1650 TNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW 1709
                L V +D    + V +  +Y  ++CGLCGN++    +D    + ++  D +  G +W
Sbjct: 966  LGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSW 1025

Query: 1710 KLP-ESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFAS 1767
            K+  + ++     +   P++C  N M     + +C IL +    F  C+++V P+     
Sbjct: 1026 KVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDV--FQDCNKLVDPEPYLDV 1083

Query: 1768 CVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGS--------- 1816
            C++  C  +  GD    C ++ AYA +CAQ G+   WR  T CP  C   +         
Sbjct: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECE 1143

Query: 1817 -SYSPCSSPCPDTCSSINNPRDCPKALPCAESC--ECQKGHILSG--TSCVPLGQCGCTD 1871
              Y+ C+  C  TC     P  CP  + C E C   C  G IL     +CV    C   +
Sbjct: 1144 WRYNSCAPACQVTCQH-PEPLACP--VQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCE 1200

Query: 1872 PAGSYHPVGERWY---TENTCTRLCTCSVHNNITC 1903
             AG     G++     ++    ++C C V  N+TC
Sbjct: 1201 VAGRRFASGKKVTLNPSDPEHCQICHCDV-VNLTC 1234



 Score =  132 bits (332), Expect = 5e-30
 Identities = 117/455 (25%), Positives = 183/455 (40%), Gaps = 63/455 (13%)

Query: 2192 QSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQ 2251
            +S   +PP+ +      L CPA +     L  C+ +C + D  C    +   C  GC+C 
Sbjct: 763  RSLSCRPPMVK------LVCPADNLRAEGL-ECTKTCQNYDLEC----MSMGCVSGCLCP 811

Query: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSH 2311
            PG V  E++CV   +C C   H G        V  GC   CVC      C D  C +   
Sbjct: 812  PGMVRHENRCVALERCPC--FHQGKEYAPGETVKIGCNT-CVCRDRKWNCTDHVCDA--- 865

Query: 2312 CQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPL 2371
                               CS  G   YLTFDG  Y   G   YVL++       G   +
Sbjct: 866  ------------------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRI 907

Query: 2372 LVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWG 2431
            LV  +    P  S    + V   V G +++L  G    VN ++   P +   H  V   G
Sbjct: 908  LVGNKGCSHP--SVKCKKRVTILVEGGEIELFDG---EVNVKR---PMKDETHFEVVESG 959

Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
            + + L+    L V +    +  + L   Y+  V GLCGN+D  + ND+   +  + ++  
Sbjct: 960  RYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPV 1019

Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLA 2551
             FGNSW+V ++ A     R +P +         +     V              +CR+L 
Sbjct: 1020 DFGNSWKVSSQCA---DTRKVPLDSSPATCHNNIMKQTMVD------------SSCRILT 1064

Query: 2552 DPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGW 2611
                 F  C++ V PEP+ + C+ D CS +   +     C  ++ YA +C + G  +  W
Sbjct: 1065 --SDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDC-ACFCDTIAAYAHVCAQHGKVVT-W 1120

Query: 2612 RDRTLCESPCLQNPCQNDG-QCREQGATFTCECEV 2645
            R  TLC   C +   + +G +C  +  +    C+V
Sbjct: 1121 RTATLCPQSCEERNLRENGYECEWRYNSCAPACQV 1155



 Score =  127 bits (320), Expect = 1e-28
 Identities = 105/445 (23%), Positives = 176/445 (39%), Gaps = 44/445 (9%)

Query: 1481 CLHPAGSYFKVGERWYKPGCKELCVCE-------SNNRIRCQPW---RCRAQEFCGQQDG 1530
            C+   G+  + G+ W  P       C+        ++R+ C       C   +   + + 
Sbjct: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938

Query: 1531 IYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENR 1590
              GC       CT S   H +TFDG      G+C+YVL +   ++ QD   ++     + 
Sbjct: 1939 TCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ---NKEQDLEVILHNGACSP 1995

Query: 1591 GGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYT 1650
            G       +K++ V    LS+ L    +V +NG  V++P       V +  +    + + 
Sbjct: 1996 GA--RQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFN 2053

Query: 1651 NFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
            + G    +    +       P ++  +  GLCG  + N  +D +  D  +  D   L   
Sbjct: 2054 HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQE 2113

Query: 1709 WKLPESSEPGCFLVGGKPSSCQ---ENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSF 1765
            W +     PG         +CQ   E       + +C +L+ P   F++CH+V+ P + +
Sbjct: 2114 WTV---QRPG--------QTCQPILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFY 2160

Query: 1766 ASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPC 1825
            A C    C  +     +C  + +YA LC   G    WR   FC M CPP   Y+ C   C
Sbjct: 2161 AICQQDSCHQE----QVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC 2216

Query: 1826 PDTC-SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC-GCTDPAGSYHPVGERW 1883
            P  C  ++++  D P     +E C C    ++   SCVP   C  C    G  H   E W
Sbjct: 2217 PRHCDGNVSSCGDHP-----SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAW 2271

Query: 1884 YTENTCTRLCTCSVHNNITCFQSTC 1908
              ++   ++CTC     + C    C
Sbjct: 2272 VPDHQPCQICTCLSGRKVNCTTQPC 2296



 Score =  115 bits (288), Expect = 6e-25
 Identities = 116/446 (26%), Positives = 161/446 (36%), Gaps = 68/446 (15%)

Query: 1104 PGAEWFSPNCTEHCRCWPGS-------RVECQISQCGTHTVCQLKNGQYGCHPYAG---T 1153
            PG  W  P+      C P         RV C     G    C             G   T
Sbjct: 1889 PGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDR---GLRPSCPNSQSPVKVEETCGCRWT 1945

Query: 1154 ATCLVYGDP--HYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211
              C+  G    H VTFDG++F   G C+Y+L Q      +      A +    Q    C+
Sbjct: 1946 CPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQ---GCM 2002

Query: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSK---GVF-----------LGASGRFV 1257
              + V     +V L       V G+ V++P +       V+           LG    F 
Sbjct: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062

Query: 1258 ELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELG 1317
                EF L++              T++ K  GLCG  D N  ND +  DG+   D + L 
Sbjct: 2063 PQNNEFQLQLS-----------PKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLV 2111

Query: 1318 NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASF 1377
              W T Q   Q CQ          DSS    +  P F             C   +  A+F
Sbjct: 2112 QEW-TVQRPGQTCQPILEEQCLVPDSSHCQVLLLPLFA-----------ECHKVLAPATF 2159

Query: 1378 FDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAK 1437
            +  C  D C     Q  +C  +++    C+  G  V  WR P FC M+CPP+  Y+ C  
Sbjct: 2160 YAICQQDSCH----QEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEH 2214

Query: 1438 PCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQC-GCLHPAGSYFKVGERW- 1495
             CP  C    S   C D   E C C P  V+    C+P   C  C+   G   +  E W 
Sbjct: 2215 GCPRHCDGNVSS--CGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWV 2272

Query: 1496 --YKPGCKELCVCESNNRIRCQPWRC 1519
              ++P C ++C C S  ++ C    C
Sbjct: 2273 PDHQP-C-QICTCLSGRKVNCTTQPC 2296



 Score =  110 bits (276), Expect = 1e-23
 Identities = 112/487 (22%), Positives = 172/487 (35%), Gaps = 94/487 (19%)

Query: 1825 CPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWY 1884
            C  TC   N   +C  ++ C   C C  G +     CV L +C C      Y P GE   
Sbjct: 788  CTKTCQ--NYDLEC-MSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAP-GE--- 840

Query: 1885 TENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDG 1944
            T       C C       C    C                      C   G +HY++FDG
Sbjct: 841  TVKIGCNTCVCR-DRKWNCTDHVCD-------------------ATCSTIGMAHYLTFDG 880

Query: 1945 SNHSIPDACTLVLVK-------------VCHPAMALPFFKISAKHEKEEGGTEAFRLHEV 1991
              +  P  C  VLV+             V +   + P  K   +      G E       
Sbjct: 881  LKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGE------- 933

Query: 1992 YIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNH 2051
             I+++D +V +++               +       V  S  Y I+ +   + V +D + 
Sbjct: 934  -IELFDGEVNVKR--------------PMKDETHFEVVESGRYIILLLGKALSVVWDRHL 978

Query: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
             + + +  TY  KVCG+CGNF+  + ++L   + +V     +F NSWK         S  
Sbjct: 979  SISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWK-------VSSQC 1031

Query: 2112 VDEQQIPAEQQENPSGNCRAADLRRAR-EKCEAALRAPVWAQCASRIDLTPFLVDCA--N 2168
             D +++P    ++    C    +++   +     L + V+  C   +D  P+L  C    
Sbjct: 1032 ADTRKVPL---DSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDT 1088

Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS----------SYT 2218
              CE  G     C  + A+   C   G K   WR ++ CP  C   +           Y 
Sbjct: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147

Query: 2219 NCLPSCSPSCWDLDGRCEGAKVPSACAEGC--ICQPGYVLSE--DKCVPRSQCGCKDAHG 2274
            +C P+C  +C       E    P  C EGC   C PG +L E    CV    C   +  G
Sbjct: 1148 SCAPACQVTC----QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203

Query: 2275 GSIPLGK 2281
                 GK
Sbjct: 1204 RRFASGK 1210



 Score =  103 bits (258), Expect = 2e-21
 Identities = 98/458 (21%), Positives = 177/458 (38%), Gaps = 56/458 (12%)

Query: 1869 CTDPAGSYHPVGERWYTENTC-TRLC-----TCSVHNNITC---FQSTCKPNQICWALDG 1919
            C D  G+    G+ W   + C T  C     T    + + C    + +C  +Q    ++ 
Sbjct: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938

Query: 1920 LLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE 1979
               CR +   VC      H V+FDG N  +  +C+ VL +     + +     +      
Sbjct: 1939 TCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGAR 1998

Query: 1980 EGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039
            +G  ++  +    +      V L     V +N + V++P +     V+V  + ++ +   
Sbjct: 1999 QGCMKSIEVKHSALS-----VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFN 2053

Query: 2040 KIGVQVKFDG-NHLLEIEI-PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
             +G    F   N+  ++++ P T+  K  G+CG  ++   ++ M+    V       V  
Sbjct: 2054 HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQE 2113

Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRI 2157
            W  +    +CQ +L ++  +P       S +C+              L  P++A+C   +
Sbjct: 2114 WTVQRPGQTCQPILEEQCLVP------DSSHCQ-------------VLLLPLFAECHKVL 2154

Query: 2158 DLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSY 2217
                F   C    C      + +C+ + ++   C++ G+    WR   FC + CP    Y
Sbjct: 2155 APATFYAICQQDSCH----QEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVY 2209

Query: 2218 TNCLPSCSPSCWDLDGRCEGAKVPSAC----AEGCICQPGYVLSEDKCVPRSQC-GCKDA 2272
             +C   C   C   DG        S+C    +EGC C P  V+ E  CVP   C  C   
Sbjct: 2210 NHCEHGCPRHC---DGNV------SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGE 2260

Query: 2273 HGGSIPLGKSWV-SSGCTEKCVC-TGGAIQCGDFRCPS 2308
             G      ++WV      + C C +G  + C    CP+
Sbjct: 2261 DGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT 2298



 Score = 85.1 bits (209), Expect = 9e-16
 Identities = 85/336 (25%), Positives = 134/336 (39%), Gaps = 48/336 (14%)

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
            C+       +TFDG +++L G  +YVL +  +   + +E +L  G     P      ++ 
Sbjct: 1950 CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGA--CSPGARQGCMKS 2004

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFEL--VVSFGG 2448
            +        V+L + +E+ VN + ++VPY    ++ V ++G  ++ V    L  + +F  
Sbjct: 2005 IEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRFNHLGHIFTFTP 2063

Query: 2449 RKNAV-ISL-PSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALL 2506
            + N   + L P  +     GLCG  D+N  ND ML  G +T +  T    W V+      
Sbjct: 2064 QNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQ------ 2117

Query: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAP 2566
                               R G        EQ     +  C+VL  P   FA CH+ +AP
Sbjct: 2118 -------------------RPGQTCQPILEEQCLVPDSSHCQVLLLPL--FAECHKVLAP 2156

Query: 2567 EPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPC 2626
              F   C  D C        +E  C+V++ YA LC+  G  +  WR    C   C  +  
Sbjct: 2157 ATFYAICQQDSC-------HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLV 2208

Query: 2627 QNDGQCREQGATFTCECEVGYGGGLCMEPRDAPPPR 2662
             N   C E G    C+  V   G    E    PP +
Sbjct: 2209 YN--HC-EHGCPRHCDGNVSSCGDHPSEGCFCPPDK 2241



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 5/96 (5%)

Query: 1044 CPPNARYESC--ACPASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSC-NCFYNND 1100
            CPP+  Y  C   CP  C     SCG    EGC C P  +  +  C+   +C  C   + 
Sbjct: 2203 CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDG 2262

Query: 1101 YYEPGAEWFSPN--CTEHCRCWPGSRVECQISQCGT 1134
                  E + P+    + C C  G +V C    C T
Sbjct: 2263 VQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT 2298



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 1044 CPPNARYESCACPAS--CKS---PRPSCGPLCREGCVCNPGFLFSDN-HCIQASSCNCFY 1097
            CP    Y  C  P +  C+S   P   C   C EGC C PG    +   C+  + C C+Y
Sbjct: 652  CPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYY 711

Query: 1098 NNDYYEPGAEWFSPNCTEHCRCWPG 1122
            + + ++P  + FS + T  C C  G
Sbjct: 712  DGEIFQP-EDIFSDHHT-MCYCEDG 734


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score =  286 bits (732), Expect = 2e-76
 Identities = 243/955 (25%), Positives = 392/955 (41%), Gaps = 112/955 (11%)

Query: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ 1478
            P  CP+  PP ++ +   +    TC  G+ G  C++   +A     G   +  +C  + Q
Sbjct: 71   PGLCPIYKPPETRPAKWNRTVR-TCCPGWGGAHCTEALAKASP--EGHCFAMWQC--QLQ 125

Query: 1479 CGCLHP-AGSYFKV-----GERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY 1532
             G  +  AGS  +      G+ W+    +    C S +           Q   G    ++
Sbjct: 126  AGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLW 185

Query: 1533 GCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGG 1592
              H + +ATC +    HY TFDG  +HF+G CTY+L     + + DS + V  T  +R  
Sbjct: 186  SQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLL-----AGAADSTWAVHLTPGDR-- 238

Query: 1593 ILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL-PVWLAQGRVTIRLSSNLVLLYTN 1651
              +  + + V +   ++   L++   V + G  V     WL  G ++++   + ++L   
Sbjct: 239  CPQPGHCQRVTMGPEEV---LIQAGNVSVKGQLVPEGQSWLLHG-LSLQWLGDWLVLSGG 294

Query: 1652 FGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKL 1711
             G+ VR D +  + ++V     GQ  GLCG YN    DD + P   LA  +   G +W+L
Sbjct: 295  LGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL 354

Query: 1712 PESSEPGCFLVGGKPSSCQENSMADA----------WNKNCAILINPQGPFSQCHQVVPP 1761
            P  SE GC         C    + DA              C  L+  +GPF QCH  V P
Sbjct: 355  P-GSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLL--EGPFGQCHAQVSP 411

Query: 1762 QSSFASCVHGQC-------GTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPP 1814
                 +C+   C       G +G   A+C +  +Y   CA+      WR   FC   CP 
Sbjct: 412  AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPG 471

Query: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
            G  YS C S CP +C ++    +      C   CEC +G   +GT CVP   C C     
Sbjct: 472  GQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC----- 526

Query: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC-RASGVGVCQL 1933
              +   +R+   +T  +LC                    C   DG   C +A     C +
Sbjct: 527  --YYCRQRYVPGDTVRQLC------------------NPCVCRDGRWHCAQALCPAECAV 566

Query: 1934 PGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFR-LHEVY 1992
             G+ HY++FDG ++S          + C  ++   + K       E G  +A   LH + 
Sbjct: 567  GGDGHYLTFDGRSYSFWGG------QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAIS 620

Query: 1993 IDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD-GNH 2051
            + + D  + L+    VL+N + V LP I    G+SV+ +S   ++    G QV +   + 
Sbjct: 621  VSLEDTHIQLRDSGAVLVNGQDVGLPWIG-AEGLSVRRASSAFLLLRWPGAQVLWGLSDP 679

Query: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
            +  I +   +  +V G+CG F   ++D+ + P+ +V  S + F + ++           +
Sbjct: 680  VAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ-----------V 728

Query: 2112 VDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLC 2171
              + + P+E     S     +      E   A L + V+ +C   +D  PF + C   +C
Sbjct: 729  AGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVC 788

Query: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231
                    LC  L A+   C  +G  PP WRN + CP+ CP    Y  C P+C   C   
Sbjct: 789  GCDPGSDCLCPVLSAYARRCAQEGASPP-WRNQTLCPVMCPGGQEYRECAPACGQHC--- 844

Query: 2232 DGRCEGAKVPSACAEGCICQPGYVLS-EDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290
             G+ E      +C  GC C  G +   E +CVP S C C+       P G + +      
Sbjct: 845  -GKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAP-GSATMKE--CN 900

Query: 2291 KCVC-TGGAIQCGDFRCPSGSHCQ-----------LTSD--NSNSNCVSDKSEQC 2331
            +C+C   G   C    CPS + C            LT D  ++N +C +  ++ C
Sbjct: 901  RCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGC 955



 Score =  285 bits (730), Expect = 3e-76
 Identities = 242/857 (28%), Positives = 346/857 (40%), Gaps = 107/857 (12%)

Query: 1143 GQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEE 1202
            GQ        +ATC  +   HY TFDGRH+ F+G+CTY+LA     + D  + V     +
Sbjct: 182  GQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLA----GAADSTWAVHLTPGD 237

Query: 1203 QGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE 1262
            +  +   C     VT+    V +  G  ++ G       +    G+ L   G ++ L   
Sbjct: 238  RCPQPGHCQR---VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGG 294

Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
             G+ VR D    + ++V     G+  GLCG Y+G  ++D ++  G  A      GNSW+ 
Sbjct: 295  LGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL 354

Query: 1323 DQDED---------QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVK 1373
               E          Q C    ++++      L++       C +L++  GPF  C   V 
Sbjct: 355  PGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQD--VCHQLLE--GPFGQCHAQVS 410

Query: 1374 AASFFDSCMLDMC-------GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
             A + ++C+   C       G +G Q  +C   ++    C    H    WR+P FC   C
Sbjct: 411  PAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARR-HIHIRWRKPGFCERLC 469

Query: 1427 PPNSKYSLCAKPCPDTCHSGFSGM--FCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
            P    YS C   CP +C +   G    C + CV  CEC  G   +G  C+P + C C + 
Sbjct: 470  PGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYY- 528

Query: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGC-HAQGAATCT 1543
                           C++  V     R  C P  CR        DG + C  A   A C 
Sbjct: 529  ---------------CRQRYVPGDTVRQLCNPCVCR--------DGRWHCAQALCPAECA 565

Query: 1544 ASGDPHYLTFDGALHHFMGT--CTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
              GD HYLTFDG  + F G   C Y L +  + + Q    +        G     S + A
Sbjct: 566  VGGDGHYLTFDGRSYSFWGGQGCRYSLVQD-YVKGQLLILL------EHGACDAGSCLHA 618

Query: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
            + V++ D  I L     V++NG  V LP W+    +++R +S+  LL    G QV +  S
Sbjct: 619  ISVSLEDTHIQLRDSGAVLVNGQDVGLP-WIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677

Query: 1662 HLVE-VTVPSSYGGQLCGLCGNYNNNSLDDNLRP----DRKLAGDSMQLGAAWKLPESSE 1716
              V  +T+   +  Q+ GLCG +  N  DD L P    +  +A  + +   A K    SE
Sbjct: 678  DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSE 737

Query: 1717 PGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
                L     S C  +S   A+ +  CAIL +    F +CH++V  +  +  C+   CG 
Sbjct: 738  DSALL-----SPCTTHSQRHAFAEAACAILHS--SVFQECHRLVDKEPFYLRCLAAVCGC 790

Query: 1776 KGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNP 1835
               +  LC  L AYA  CAQ G +P WRN+T CP+ CP G  Y  C+  C   C     P
Sbjct: 791  DPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKP 847

Query: 1836 RDCPKALPCAESCECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCT 1894
             DC +   C   C C  G +      CVP   C C   A  Y P      T   C R C 
Sbjct: 848  EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSA---TMKECNR-CI 903

Query: 1895 CSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIP---- 1950
            C       C    C     C       R      G C L  +S       +NHS P    
Sbjct: 904  CQERGLWNCTARHCPSQAFC------PRELVYAPGACLLTCDS-----PSANHSCPAGST 952

Query: 1951 DACTLVLVKVCHPAMAL 1967
            D C      VC P   L
Sbjct: 953  DGC------VCPPGTVL 963



 Score =  264 bits (674), Expect = 1e-69
 Identities = 246/949 (25%), Positives = 363/949 (38%), Gaps = 189/949 (19%)

Query: 1044 CPPNARYESCA--CPASCKS----PRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFY 1097
            CP    Y  C   CP SC++       SC   C  GC C  G  ++   C+ A+ C C+Y
Sbjct: 469  CPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYY 528

Query: 1098 NNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
                Y PG        T    C P                C  ++G++ C      A C 
Sbjct: 529  CRQRYVPGD-------TVRQLCNP----------------CVCRDGRWHCAQALCPAECA 565

Query: 1158 VYGDPHYVTFDGRHFGFMG--KCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
            V GD HY+TFDGR + F G   C Y L Q          ++    E    +  SCL  + 
Sbjct: 566  VGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKG-----QLLILLEHGACDAGSCLHAIS 620

Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
            V+L ++ + L      LV GQ V LP       ++GA G  V   +   L +RW G Q L
Sbjct: 621  VSLEDTHIQLRDSGAVLVNGQDVGLP-------WIGAEGLSVRRASSAFLLLRWPGAQVL 673

Query: 1276 --------YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
                    Y+T+   ++ ++ GLCG +  N  +D L    +PAGD E    ++       
Sbjct: 674  WGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFL----TPAGDVETSIAAF------- 722

Query: 1328 QECQKYQVVNS---PSCDSSLQSSMS--------GPGFCGRLVDTHGPFETCLLHVKAAS 1376
                K+QV      PS DS+L S  +            C  L  +   F+ C   V    
Sbjct: 723  --ASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEP 778

Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
            F+  C+  +CG       LC  +S     C   G A  PWR    CP+ CP   +Y  CA
Sbjct: 779  FYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECA 837

Query: 1437 KPCPDTCHSGFSGMFCSD--RCVEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGE 1493
              C   C        C +   CV  C C  G +     +C+P S C C        ++G 
Sbjct: 838  PACGQHCGKPED---CGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPC--------QLGA 886

Query: 1494 RWYKPGCKEL-----CVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAA--TCTASG 1546
            R Y PG   +     C+C+      C    C +Q FC ++      +A GA   TC +  
Sbjct: 887  RRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRE----LVYAPGACLLTCDSPS 942

Query: 1547 DPHYLTFDGALHHFMGTCTYVLTRPCW------SRSQDSYFVVSA--------------- 1585
              H               T +L   C        R    +++ +A               
Sbjct: 943  ANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQ 1002

Query: 1586 ---TNENRGGILEVSYIKAVHVTVFD-LSISLLRGCKVMLNGHRVALPVWLAQG------ 1635
               T + R G  + S   A H   FD L+ +    C+ +L      L    AQ       
Sbjct: 1003 WHCTGQRRSGRCQAS--GAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGAS 1060

Query: 1636 ------RVTIRLSSNLV------------------LLYTNFGLQVR-------------- 1657
                   + +RL   +V                   +YT  GL +R              
Sbjct: 1061 GLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGL 1120

Query: 1658 ---YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGA-AWKLPE 1713
               +DG   V V +   + G++ GLCG+++ ++ +D LR  + +   + +L A +W+L  
Sbjct: 1121 TLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASND-LRSRQGVLEPTAELAAHSWRL-- 1177

Query: 1714 SSEPGCFLVGGKPSSCQENSMADAWNK-NCAILINPQGPFSQCHQVVPPQSSFASCVHGQ 1772
               P C   G  P  C  N+    W +  C  L+ P   F+ CH  VPPQ  +  C++  
Sbjct: 1178 --SPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDA 1233

Query: 1773 CG--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
            CG  + GD   LC ++  YA  CA+ G    WR++  C ++C  G  Y  C   CP TC 
Sbjct: 1234 CGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCH 1293

Query: 1831 SIN-NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHP 1878
              +  P    + + C E C C +G +L G +C+    C C     S+ P
Sbjct: 1294 EQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPP 1342



 Score =  214 bits (545), Expect = 9e-55
 Identities = 154/538 (28%), Positives = 219/538 (40%), Gaps = 72/538 (13%)

Query: 1044 CPPNARYESCACPASCKSPRP--SCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDY 1101
            CP    Y   AC  +C SP    SC     +GCVC PG +  D  C+    C C ++   
Sbjct: 923  CPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSG-- 980

Query: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGD 1161
                 +W+ PN T    C                 VC  +  Q+ C     +  C   G 
Sbjct: 981  -----QWYLPNATIQEDC----------------NVCVCRGRQWHCTGQRRSGRCQASGA 1019

Query: 1162 PHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPES 1221
            PHYVTFDG  F + G C Y+L +         F V+A+N   G  G++C   + V L  +
Sbjct: 1020 PHYVTFDGLAFTYPGACEYLLVREASG----LFTVSAQNLPCGASGLTCTKALAVRLEGT 1075

Query: 1222 TVTLLKGRRTLVGGQQVTLPAI-PSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVS 1280
             V +L+GR   V G  VT P +    G+ L  +G F+ L T  GL + WDG  ++ V +S
Sbjct: 1076 VVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLS 1135

Query: 1281 STYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPS 1340
              + G++ GLCG++DG++ ND     G      E   +SW+        C +   +  P 
Sbjct: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----SPLCPEPGDLPHP- 1190

Query: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTH 1398
            C  +   +      CG L+     F  C   V     ++ C+ D CG    G    LC+ 
Sbjct: 1191 CTMNTHRAGWARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248

Query: 1399 MSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF--SGMFCS-DR 1455
            ++T    C   GH V+ WR    C + C     Y  C   CP TCH      G  C    
Sbjct: 1249 IATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVA 1307

Query: 1456 CVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVG--------ERWYKPG--- 1499
            CVE C C  G +L G  C+  + C C       P GS  +           +W+  G   
Sbjct: 1308 CVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGG 1367

Query: 1500 -CKEL--------CVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHA----QGAATCTA 1544
             C+EL         +C+ N       W C  Q+ CG      GC A    +G  TC++
Sbjct: 1368 HCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSS 1425



 Score =  175 bits (443), Expect = 6e-43
 Identities = 204/885 (23%), Positives = 333/885 (37%), Gaps = 110/885 (12%)

Query: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
            CP+  PP +  +  +      C        C +AL  A      +GH  +   C  L   
Sbjct: 74   CPIYKPPETRPAKWNRTVRTCCPGWGGAH-CTEALAKASP----EGHCFAMWQC-QLQAG 127

Query: 1868 GCTDPAGSYH-----PVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
                 AGS       P G+ W+ + +     +CS  +      S      +  A+  L  
Sbjct: 128  SANASAGSLEECCARPWGQSWW-DGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWS 186

Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
                    C      HY +FDG ++     CT +L        A+    ++      + G
Sbjct: 187  QHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAV---HLTPGDRCPQPG 243

Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
                  H   + +   +V +Q G+ V +  + V       + G+S++    + +++  +G
Sbjct: 244  ------HCQRVTMGPEEVLIQAGN-VSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLG 296

Query: 2043 VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD 2102
            V V+ D    + I +    +G+  G+CG +N   ED+ M P   +A   + F NSW+   
Sbjct: 297  VVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPG 356

Query: 2103 IDPSCQSLLVDEQ---QIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159
             +  C   +   Q    +     +   G+ RA     A++ C   L  P + QC +++  
Sbjct: 357  SESGCLDAVEVAQGCDPLGLIDADVEPGHLRA----EAQDVCHQLLEGP-FGQCHAQVSP 411

Query: 2160 TPF-----LVDCANTLCEFG--GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECP 2212
              +        CA  +   G  G  QA+C    ++   C  + +    WR   FC   CP
Sbjct: 412  AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCP 470

Query: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDA 2272
                Y++C+  C PSC +  G+ E       C  GC C  G   +   CVP + C C   
Sbjct: 471  GGQLYSDCVSLCPPSC-EAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYC 529

Query: 2273 HGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCS 2332
                +P     V   C   CVC  G   C    CP+                     +C+
Sbjct: 530  RQRYVP--GDTVRQLCNP-CVCRDGRWHCAQALCPA---------------------ECA 565

Query: 2333 VYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVI 2392
            V GD  YLTFDG SY   G          D +   +  LL  G        +   L  + 
Sbjct: 566  VGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACD-----AGSCLHAIS 620

Query: 2393 TTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFG-GRKN 2451
             ++    +QL+    ++VN Q + +P+   E L V        L+      V +G     
Sbjct: 621  VSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPV 680

Query: 2452 AVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRA 2511
            A I+L   +   V GLCG + +N+++D + P+G +  ++  F + ++V  +         
Sbjct: 681  AYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKG-------R 733

Query: 2512 IPAEEEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQ 2570
             P+E+              +S C+   Q  + +  AC +L      F  CH+ V  EPF 
Sbjct: 734  CPSEDSA-----------LLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFY 780

Query: 2571 EHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCE------------ 2618
              C+  +C   DP    +  C VLS YA  C + GA+   WR++TLC             
Sbjct: 781  LRCLAAVCGC-DP--GSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYREC 836

Query: 2619 SPCLQNPCQNDGQCREQGATFT-CECEVGY---GGGLCMEPRDAP 2659
            +P     C     C E G+    C C +G      G C+ P   P
Sbjct: 837  APACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCP 881



 Score =  166 bits (420), Expect = 3e-40
 Identities = 152/603 (25%), Positives = 234/603 (38%), Gaps = 76/603 (12%)

Query: 1717 PGCFLVGGKPSSCQE-NSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
            P C    GKP  C E  S     N    +L +P+G      Q VPP  S   C   Q G 
Sbjct: 838  PACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEG------QCVPP--SLCPC---QLGA 886

Query: 1776 KGDTTALCRSLQAYASLCAQAGQAPAWR-NRTFCPMR--CPPGSSYSPCSSPCPDTCSSI 1832
            +          +    +C + G    W      CP +  CP    Y+P    C  TC S 
Sbjct: 887  RRYAPGSATMKECNRCICQERG---LWNCTARHCPSQAFCPRELVYAP--GACLLTCDSP 941

Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
            +    CP      + C C  G +L    CVP   C C            +WY  N   + 
Sbjct: 942  SANHSCPAG--STDGCVCPPGTVLLDERCVPPDLCPCRHSG--------QWYLPNATIQE 991

Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
                      C    C+  Q  W   G  R      G CQ  G  HYV+FDG   + P A
Sbjct: 992  ---------DCNVCVCRGRQ--WHCTGQRRS-----GRCQASGAPHYVTFDGLAFTYPGA 1035

Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINS 2012
            C  +LV+      A   F +SA++    G +       + + +    V + +G  V +N 
Sbjct: 1036 CEYLLVRE-----ASGLFTVSAQN-LPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNG 1089

Query: 2013 KQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNF 2072
              VT P +   PG+S++ + ++ +++  +G+ + +DG   + +++   + G+V G+CG+F
Sbjct: 1090 VSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDF 1149

Query: 2073 NDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAA 2132
            + +  ++L      +  +     +SW+   + P C          P +     + N   A
Sbjct: 1150 DGDASNDLRSRQGVLEPTAELAAHSWR---LSPLCPE--------PGDLPHPCTMNTHRA 1198

Query: 2133 DLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGAT 2190
               RAR  C A L+ P++  C + +        C      C+ GG  + LC A+  +   
Sbjct: 1199 GWARAR--CGALLQ-PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255

Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
            C   G     WR+   C L+C     Y  C P+C P+C +            AC EGC C
Sbjct: 1256 CARHG-HHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFC 1314

Query: 2251 QPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310
              G +L    C+  + C C+     S P G S +   C   C C  G   CG      G 
Sbjct: 1315 PEGTLLHGGACLEPASCPCEWGR-NSFPPG-SVLQKDC-GNCTCQEGQWHCGG----DGG 1367

Query: 2311 HCQ 2313
            HC+
Sbjct: 1368 HCE 1370



 Score =  120 bits (301), Expect = 2e-26
 Identities = 121/497 (24%), Positives = 177/497 (35%), Gaps = 96/497 (19%)

Query: 2191 CQSQGLKPPLWRN---SSFCPLE---CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSAC 2244
            CQ +GL     R+    +FCP E    P     T   PS + SC            P+  
Sbjct: 904  CQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSC------------PAGS 951

Query: 2245 AEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDF 2304
             +GC+C PG VL +++CVP   C C+  H G   L  + +   C   CVC G    C   
Sbjct: 952  TDGCVCPPGTVLLDERCVPPDLCPCR--HSGQWYLPNATIQEDCNV-CVCRGRQWHCTGQ 1008

Query: 2305 RCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVL 2364
            R                     +S +C   G P Y+TFDG ++   G   Y+L++    L
Sbjct: 1009 R---------------------RSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL 1047

Query: 2365 PEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVP-YRPNE 2423
                    V  +N           + +   + G  V +  G  + VN   +  P      
Sbjct: 1048 ------FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGP 1101

Query: 2424 HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPS 2483
             L +   G  L L T   L + + G    ++ L   + G V+GLCG++D +  ND+    
Sbjct: 1102 GLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQ 1161

Query: 2484 GALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNS 2543
            G L        +SW +     L   P  +P                    C+     +  
Sbjct: 1162 GVLEPTAELAAHSWRL---SPLCPEPGDLP------------------HPCTMNTHRAGW 1200

Query: 2544 TQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQ 2602
             +A C  L  P   F  CH  V P+   E C+ D C      + E L C  ++ YA  C 
Sbjct: 1201 ARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECL-CSAIATYADECA 1257

Query: 2603 EAGAALAGWRDRTLCESPC------------------LQNPCQNDGQCREQGATFTCECE 2644
              G  +  WR + LC   C                   Q+P +    C+       C C 
Sbjct: 1258 RHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHP-EPGWHCQVVACVEGCFCP 1315

Query: 2645 VG--YGGGLCMEPRDAP 2659
             G    GG C+EP   P
Sbjct: 1316 EGTLLHGGACLEPASCP 1332



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 4/107 (3%)

Query: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
            C   CP G     C++ CP  CS +     C     C + C C KG +     CVP+G C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117

Query: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQIC 1914
             CTD  G     G +   ++ C   C+C     ++C    C P   C
Sbjct: 4118 DCTDAQGHSWAPGSQ--HQDACNN-CSCQA-GQLSCTAQPCPPPTHC 4160



 Score = 63.5 bits (153), Expect = 3e-09
 Identities = 37/96 (38%), Positives = 43/96 (44%), Gaps = 19/96 (19%)

Query: 1434 LCAK----PCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYF 1489
            LC K    PCP +C    +   CS  CVE C C PG +L    C+P S+C CL       
Sbjct: 2626 LCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCL------- 2678

Query: 1490 KVGERWYKPGCKEL------CVCESNNRIRCQPWRC 1519
             VGE    PG   L      CVCE    + CQP  C
Sbjct: 2679 -VGEELKWPGVSFLLGNCSQCVCE-KGELLCQPGGC 2712



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 41/138 (29%), Positives = 53/138 (38%), Gaps = 8/138 (5%)

Query: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR--CEGAKVPSACA 2245
            GA C  +  +  L  N   C   CPA      C   C   C DL     C+  +V   C 
Sbjct: 4040 GAPCAGERHQARLC-NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQV---CQ 4095

Query: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFR 2305
            +GC C  G +  +  CVP   C C DA G S   G           C C  G + C    
Sbjct: 4096 KGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQ--HQDACNNCSCQAGQLSCTAQP 4153

Query: 2306 CPSGSHCQLTSDNSNSNC 2323
            CP  +HC  +  ++ S C
Sbjct: 4154 CPPPTHCAWSHWSAWSPC 4171



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 48/173 (27%), Positives = 66/173 (38%), Gaps = 35/173 (20%)

Query: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGC 2248
            A CQ+Q  +     N   CP ECP     + C  SC   CW L       + P  C  GC
Sbjct: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGC 4853

Query: 2249 ICQPGYVLSEDKCVPRSQCGCK------------DAHGGSIPLGKSWVSSGCTEKCVCTG 2296
             C  G +L    CVP + C C             +     +P G + ++  CT +CVC G
Sbjct: 4854 GCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPG-TVLTRNCT-RCVCHG 4911

Query: 2297 GAIQCG--DFRCPSGSHCQ----------------LTSDNSNSNCVSDKSEQC 2331
            GA  C   D + P G   Q                + +  + SNC S ++  C
Sbjct: 4912 GAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGC 4964



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 30/80 (37%), Positives = 37/80 (46%), Gaps = 4/80 (5%)

Query: 1055 CPASCKSPRP--SCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPN 1112
            CP SC  P+   SC   C EGC C PG L  D  C+  S C C    +   PG  +   N
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694

Query: 1113 CTEHCRCWPGSRVECQISQC 1132
            C++ C C  G  + CQ   C
Sbjct: 2695 CSQ-CVCEKGELL-CQPGGC 2712



 Score = 58.5 bits (140), Expect = 9e-08
 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 9/89 (10%)

Query: 2221 LPSCSPSCWD--LDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIP 2278
            +P C PSC D   +  C G      C EGC C PG +L + +C+P S+C C        P
Sbjct: 2632 VPPCPPSCLDPKANRSCSGH-----CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWP 2686

Query: 2279 LGKSWVSSGCTEKCVCTGGAIQCGDFRCP 2307
             G S++   C++ CVC  G + C    CP
Sbjct: 2687 -GVSFLLGNCSQ-CVCEKGELLCQPGGCP 2713



 Score = 58.5 bits (140), Expect = 9e-08
 Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 15/113 (13%)

Query: 2203 NSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCE--------GAKVPSACAEGCICQPGY 2254
            N+  C  +CP      N L   +  C    G C         G +    CA GC C PG 
Sbjct: 2878 NTQPCTAQCPE-----NMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGL 2932

Query: 2255 VLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCP 2307
             L    C+PRSQC C+  HG     G       C   C C  G + C   RCP
Sbjct: 2933 FLHNASCLPRSQCPCQ-LHGQLYASGAMARLDSC-NNCTCVSGKMACTSERCP 2983



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 39/131 (29%), Positives = 52/131 (39%), Gaps = 12/131 (9%)

Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAK------PCPDTCHSGFSG 1449
            C+ ++   TTC    H+         C   CP N  +    +      PCP  C +   G
Sbjct: 2857 CSSLAPGDTTCPGP-HSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915

Query: 1450 MFCSDRCVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCES 1508
            + C+  C   C C PG  L    C+PRSQC C LH  G  +  G       C   C C S
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLH--GQLYASGAMARLDSCNN-CTCVS 2972

Query: 1509 NNRIRCQPWRC 1519
              ++ C   RC
Sbjct: 2973 -GKMACTSERC 2982



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 59/202 (29%), Positives = 74/202 (36%), Gaps = 38/202 (18%)

Query: 1712 PESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPP--QSSFASCV 1769
            PE+ E  C L G     C     A  W         P GP+S C +      +S   +C 
Sbjct: 3237 PEAEEEPCLLQG-----CDR---AGGWG--------PWGPWSHCSRSCGGGLRSRTRACD 3280

Query: 1770 HGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
                   GD    C   +A   +C QA   P     T C      G+ YSPC  PCP +C
Sbjct: 3281 QPPPQGLGD---YCEGPRAQGEVC-QALPCPV----TNCT--AIEGAEYSPCGPPCPRSC 3330

Query: 1830 SSINNPRDCPKALPCAESCECQKGHILS--GTSCVPLGQCGCTD-PAGSYHPVGERWYTE 1886
              + +   C     C   C C  G +LS  G  CV  G C C D   G  H  G R    
Sbjct: 3331 DDLVH---C--VWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARP 3385

Query: 1887 NTCTRLCTCSVHNNITCFQSTC 1908
            + C   CTC +   + C    C
Sbjct: 3386 DGCNH-CTC-LEGRLNCTDLPC 3405



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 3/120 (2%)

Query: 1751 PFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPM 1810
            P  +C  V+ P S+++SC     G   +    C      A   AQ  +     N   CP 
Sbjct: 4759 PHQEC-PVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCP- 4816

Query: 1811 RCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCT 1870
             CPPG   S C++ CP  C  +     C +  PC   C C  G +L   +CVP   C CT
Sbjct: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQE-PCQPGCGCPGGQLLHNGTCVPPTACPCT 4875



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 25/134 (18%)

Query: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPL-ECPAY--SSYTNCLPSCSPSCWDLDGRCEG 2237
            C+  +A G  CQ+             CP+  C A   + Y+ C P C  SC DL      
Sbjct: 3291 CEGPRAQGEVCQALP-----------CPVTNCTAIEGAEYSPCGPPCPRSCDDL------ 3333

Query: 2238 AKVPSACAEGCICQPGYVLSEDK--CVPRSQCGCKDAHGGS--IPLGKSWVSSGCTEKCV 2293
                  C  GC C PG VLS +   CV    C C D   G    P  +     GC   C 
Sbjct: 3334 VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CT 3392

Query: 2294 CTGGAIQCGDFRCP 2307
            C  G + C D  CP
Sbjct: 3393 CLEGRLNCTDLPCP 3406



 Score = 53.1 bits (126), Expect = 4e-06
 Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 13/117 (11%)

Query: 1044 CPPNARYESCAC-PASC---KSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
            CP + ++  CA  PASC    +PR +    C  GC C  G L  +N C+    C C +  
Sbjct: 3090 CPRDKQWLDCAQGPASCAELSAPRGT-NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148

Query: 1100 DYYEPGAEWFSP--NCT------EHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCH 1148
              Y PG+    P  NC+       +C  WP +  E   S     + C    G   CH
Sbjct: 3149 HLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCH 3205



 Score = 53.1 bits (126), Expect = 4e-06
 Identities = 36/114 (31%), Positives = 47/114 (41%), Gaps = 18/114 (15%)

Query: 2203 NSSFCPLECPAYSSY--TNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDK 2260
            N   CP EC A  +    +C   C  SC DL  R +  + P  C  GC C PG ++ + +
Sbjct: 4660 NGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGR 4716

Query: 2261 CVPRSQCGCKDAHGGSIPLGKSW-------VSSGCTEKCVCTGGAIQCGDFRCP 2307
            CVP S C C     G      SW       V   C + C C   ++ C    CP
Sbjct: 4717 CVPISSCRC-----GLPSANASWELAPAQAVQLDC-QNCTCVNESLVCPHQECP 4764



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 56/211 (26%), Positives = 81/211 (38%), Gaps = 36/211 (17%)

Query: 2192 QSQGLKPP--LWRNSSFCPLECPAYS-SYTNC---------------LPSCSPSCWDLDG 2233
            Q+Q L P   L RN + C     A+S S  +C               L  C  +C +++ 
Sbjct: 4890 QAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNA 4949

Query: 2234 RCEGAKVPSACAEGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKC 2292
                +   SA A GC+CQPG+  S+   CVP   C C       +P G  W  +   E C
Sbjct: 4950 TKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLP-GSEWQEA--CESC 5006

Query: 2293 VCTGG----AIQCGDFRCPSGSHCQLTSDNSNSNC----VSDKSEQCSVYGDPRYLTFDG 2344
            +C  G       C    C  G    L   +   +C      ++S  C +  + R  T  G
Sbjct: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFT-KG 5065

Query: 2345 FSYRLQGRMTY---VLIKTVDVLPEGVEPLL 2372
              Y  Q  ++Y       +  V+PE  EP L
Sbjct: 5066 TCYLDQVEVSYCSGYCPSSTHVMPE--EPYL 5094



 Score = 52.0 bits (123), Expect = 8e-06
 Identities = 31/102 (30%), Positives = 41/102 (40%), Gaps = 9/102 (8%)

Query: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIPRSQCGCL 1482
            +C P  ++  C  PC   C +  S   C D   C   C C  G +     CIP  +C C 
Sbjct: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCW 4481

Query: 1483 HP----AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCR 1520
            H     AG     G+R  + GCKE C C     + C    C+
Sbjct: 4482 HTSAAGAGMTLAPGDR-LQLGCKE-CECR-RGELHCTSQGCQ 4520



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 8/91 (8%)

Query: 1048 ARYESCA--CPASCKSPRPSCGPLCREGCVCNPGFLFSDNH--CIQASSCNC--FYNNDY 1101
            A Y  C   CP SC      C   C+ GC C PG + S N   C+Q   C+C        
Sbjct: 3317 AEYSPCGPPCPRSCDD-LVHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQR 3375

Query: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
            + PGA    P+   HC C  G R+ C    C
Sbjct: 3376 HHPGARLARPDGCNHCTCLEG-RLNCTDLPC 3405



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 12/102 (11%)

Query: 1041 TERCPPNARYESCA--------CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQA 1090
            T +CP N  + S          CP  C +  P   C   C  GC C PG    +  C+  
Sbjct: 2883 TAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPR 2942

Query: 1091 SSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
            S C C  +   Y  GA     +C  +C C  G ++ C   +C
Sbjct: 2943 SQCPCQLHGQLYASGAMARLDSC-NNCTCVSG-KMACTSERC 2982



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)

Query: 1800 PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDC-PKALPCAESCECQKGHILSG 1858
            P   N T C   C  G S  PC  PCP +C  ++    C P ++ C  +C C  G +   
Sbjct: 3518 PCQENSTQCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQD 3576

Query: 1859 TSCVPLGQCGCTDPAGS 1875
              CVP   C C    G+
Sbjct: 3577 GLCVPPAHCRCQYQPGA 3593



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 28/109 (25%), Positives = 41/109 (37%), Gaps = 5/109 (4%)

Query: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIPR 1476
            P  C   CP   +   CA  CP  C     G+ C D   C + C C  G +     C+P 
Sbjct: 4055 PMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPI 4114

Query: 1477 SQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFC 1525
              C C    G  +  G + ++  C   C C++  ++ C    C     C
Sbjct: 4115 GHCDCTDAQGHSWAPGSQ-HQDACNN-CSCQA-GQLSCTAQPCPPPTHC 4160



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 38/122 (31%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 1783 CRSLQAYASLCAQA-GQAPAWRNRTFCPMRCPPGSS------YSPCSSPCPDTCSSINNP 1835
            C S Q     CA   G   + R    CP    P ++      + PC+ PCP TC  I+  
Sbjct: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCA-PCPLTCDDISGQ 1834

Query: 1836 RDCPKALPC-AESCECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
              CP   PC +  C C +G +L     CV   QC C      Y P G+R   +    +LC
Sbjct: 1835 VTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWP-GQRIKAD---CQLC 1890

Query: 1894 TC 1895
             C
Sbjct: 1891 IC 1892



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 9/94 (9%)

Query: 1430 SKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLS--GLECIPRSQCGCLH-PAG 1486
            ++YS C  PCP +C      + C  RC   C C PG VLS  G  C+    C CL    G
Sbjct: 3317 AEYSPCGPPCPRSCDDL---VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTG 3373

Query: 1487 SYFKVGERWYKP-GCKELCVCESNNRIRCQPWRC 1519
                 G R  +P GC   C C    R+ C    C
Sbjct: 3374 QRHHPGARLARPDGCNH-CTC-LEGRLNCTDLPC 3405



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 2/66 (3%)

Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC-- 1869
            C P   +  C SPC   C++  + + C    PC   C C KG +     C+P  +C C  
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482

Query: 1870 TDPAGS 1875
            T  AG+
Sbjct: 4483 TSAAGA 4488



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 4/89 (4%)

Query: 1821 CSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDP-AGSYHPV 1879
            C++ CP +C+ + +   C +  PC   C C  G ++    CVP+  C C  P A +   +
Sbjct: 4678 CANQCPHSCADLWDRVQCLQG-PCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWEL 4736

Query: 1880 GERWYTENTCTRLCTCSVHNNITCFQSTC 1908
                  +  C   CTC V+ ++ C    C
Sbjct: 4737 APAQAVQLDCQN-CTC-VNESLVCPHQEC 4763



 Score = 45.8 bits (107), Expect = 6e-04
 Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 4/101 (3%)

Query: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCL 1482
            P  CP + ++  CA+  P +C    +    +  C   C C  G +L    C+P   C C 
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145

Query: 1483 HPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQE 1523
            H  G  +  G    +P C E C C S     C  W C   E
Sbjct: 3146 H-EGHLYPPGSTVVRP-C-ENCSCVSGLIANCSSWPCAEGE 3183



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 49/209 (23%), Positives = 69/209 (33%), Gaps = 30/209 (14%)

Query: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADA-WNKNCAILINPQGPFSQCHQVVP------- 1760
            W    S    C   GG P     + +  +  + +C      + P S     VP       
Sbjct: 2778 WTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWA 2837

Query: 1761 PQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSP 1820
            P S+ ++   G   T+G +   C SL    + C          N   C  +CP    +  
Sbjct: 2838 PWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRS 2894

Query: 1821 CSS------PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
                     PCP  C +     +C     CA  C C  G  L   SC+P  QC C     
Sbjct: 2895 AEQCHQEGGPCPRLCLTQGPGIECTGF--CAPGCTCPPGLFLHNASCLPRSQCPC----- 2947

Query: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITC 1903
                +  + Y      RL +C   NN TC
Sbjct: 2948 ---QLHGQLYASGAMARLDSC---NNCTC 2970



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 8/103 (7%)

Query: 2208 PLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQC 2267
            P  CP    + +C    + SC +L            C  GC C  G +L  + CVP   C
Sbjct: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAP---RGTNQTCHPGCHCPSGMLLLNNVCVPTQDC 3142

Query: 2268 GCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAI-QCGDFRCPSG 2309
             C  AH G +    S V   C E C C  G I  C  + C  G
Sbjct: 3143 PC--AHEGHLYPPGSTVVRPC-ENCSCVSGLIANCSSWPCAEG 3182



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 23/129 (17%)

Query: 2199 PLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLD--GRCEGAKVPSACAEGCICQPGYVL 2256
            P   NS+ C  +C    S   C   C  SC DL     C+   V   C   C C  G + 
Sbjct: 3518 PCQENSTQCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSV--GCQPTCGCPLGQLS 3574

Query: 2257 SEDKCVPRSQCGCKDAHGG-SIPLGK---------SW-------VSSGCTEKCVCTGGAI 2299
             +  CVP + C C+   G   IP  +         SW       V +G  + C C  G +
Sbjct: 3575 QDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGIL 3634

Query: 2300 QCGDF-RCP 2307
            QC +   CP
Sbjct: 3635 QCQEVPDCP 3643



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 1422 CPMACPPNSKYSLCAKPCPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLECIPRSQCG 1480
            CP  CPP    S CA  CP  C     G  C  + C   C C  G +L    C+P + C 
Sbjct: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873

Query: 1481 C 1481
            C
Sbjct: 4874 C 4874



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 20/146 (13%)

Query: 1774 GTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
            G +  T    RSL  +++   Q    P        P  CP    +  C+   P +C+ ++
Sbjct: 3059 GYRNRTRGSSRSLMEFSTCGLQPCAGPV-------PGMCPRDKQWLDCAQG-PASCAELS 3110

Query: 1834 NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
             PR   +   C   C C  G +L    CVP   C C      Y P        +T  R C
Sbjct: 3111 APRGTNQT--CHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPP-------GSTVVRPC 3161

Query: 1894 -TCSVHNNI--TCFQSTCKPNQICWA 1916
              CS  + +   C    C   +  W+
Sbjct: 3162 ENCSCVSGLIANCSSWPCAEGEPTWS 3187



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 1824 PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC 1869
            PCP +C      R C     C E C C  G +L  T C+PL +C C
Sbjct: 2634 PCPPSCLDPKANRSCSGH--CVEGCRCPPGLLLHDTRCLPLSECPC 2677



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 22/45 (48%), Positives = 23/45 (51%), Gaps = 5/45 (11%)

Query: 1055 CPASCKS--PRPSC--GPLCREGCVCNPGFLFSDNHCIQASSCNC 1095
            CP SC     R  C  GP CR GC C PG L  D  C+  SSC C
Sbjct: 4682 CPHSCADLWDRVQCLQGP-CRPGCRCPPGQLVQDGRCVPISSCRC 4725



 Score = 42.0 bits (97), Expect = 0.008
 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 10/102 (9%)

Query: 1044 CPPNARYESCA--CPASCKSPRPSC----GPLCREGCVCNPGFLFSDNHCIQASSCNCFY 1097
            CP      +CA  CP  C   +         +C++GC C  G L  D  C+    C+C  
Sbjct: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTD 4121

Query: 1098 NNDY-YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138
               + + PG++    +   +C C  G ++ C    C   T C
Sbjct: 4122 AQGHSWAPGSQ--HQDACNNCSCQAG-QLSCTAQPCPPPTHC 4160



 Score = 42.0 bits (97), Expect = 0.008
 Identities = 28/114 (24%), Positives = 41/114 (35%), Gaps = 26/114 (22%)

Query: 1045 PPNARYESCA------CPASC-----KSPRPSCGPLCREGCVCNPGFLFSD-NHCIQASS 1092
            PP   ++  A      C  +C        + +C      GCVC PG   S    C+    
Sbjct: 4924 PPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983

Query: 1093 CNCFYNNDYYEPGAEWFS-----------PNCTEHC---RCWPGSRVECQISQC 1132
            C C++    + PG+EW             P CT+HC    C  G  +  +   C
Sbjct: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSC 5037



 Score = 40.8 bits (94), Expect = 0.018
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 1410 GHAVKPWREPHF----CPMACPPNSKYSL-CAKPCPDTCHSGFSGMFC-SDRCVEACECN 1463
            G   +PW +       CP     ++ ++L CA  CP +C   +  + C    C   C C 
Sbjct: 4648 GGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCP 4707

Query: 1464 PGFVLSGLECIPRSQCGCLHPAGS 1487
            PG ++    C+P S C C  P+ +
Sbjct: 4708 PGQLVQDGRCVPISSCRCGLPSAN 4731



 Score = 38.5 bits (88), Expect = 0.091
 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 22/107 (20%)

Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL---CREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
            CPP     +CA  CP  C   +P    +   C+ GC C  G L  +  C+  ++C C  +
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQH 4877

Query: 1099 NDYY------EPGAEWFSP------NCTEHCRCWPG----SRVECQI 1129
            +  +      E  A+   P      NCT  C C  G    S V+CQ+
Sbjct: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCT-RCVCHGGAFSCSLVDCQV 4923



 Score = 37.7 bits (86), Expect = 0.16
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 6/69 (8%)

Query: 1037 SRSSTERCPPNARYESCACPAS--CKS--PRPSCG--PLCREGCVCNPGFLFSDNHCIQA 1090
            S  S + C P   + +C  P +  C +      C   P C+ GC C  G L     CI  
Sbjct: 4416 SNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPP 4475

Query: 1091 SSCNCFYNN 1099
              CNC++ +
Sbjct: 4476 EECNCWHTS 4484



 Score = 37.4 bits (85), Expect = 0.20
 Identities = 48/164 (29%), Positives = 63/164 (38%), Gaps = 22/164 (13%)

Query: 1786 LQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSP---CSSPCPD-----TCSSINNPR 1836
            ++A   LC  Q G+    R    C + C   SS+SP   C  PC       +  S NNPR
Sbjct: 1883 IKADCQLCICQDGRPRRCRLNPDCAVDCG-WSSWSPWAKCLGPCGSQSIQWSFRSSNNPR 1941

Query: 1837 DCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
               +   C       +G       C      GC +  G  H VGERW+    C R+C C 
Sbjct: 1942 PSGRGRQC-------RGIHRKARRCQTEPCEGC-EHQGQVHRVGERWH-GGPC-RVCQCL 1991

Query: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYV 1940
              +N+T   S   P   C     L+         C LPGE+  V
Sbjct: 1992 --HNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTV 2033



 Score = 37.4 bits (85), Expect = 0.20
 Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 5/109 (4%)

Query: 1384 DMCGFQGLQHLLCTHMSTMT--TTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPD 1441
            DMC  Q  +   C+   T      C       +P +E       C        C +PCP 
Sbjct: 3485 DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPR 3544

Query: 1442 TCHSGFSGMFC---SDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGS 1487
            +C     G  C   S  C   C C  G +     C+P + C C +  G+
Sbjct: 3545 SCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGA 3593



 Score = 36.6 bits (83), Expect = 0.35
 Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 4/66 (6%)

Query: 2244 CAEGCICQPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGK-SWVSSGCTEKCVCTGGAIQ 2300
            C  GC C  G +     C+P  +C C    A G  + L     +  GC E C C  G + 
Sbjct: 4455 CQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKE-CECRRGELH 4513

Query: 2301 CGDFRC 2306
            C    C
Sbjct: 4514 CTSQGC 4519



 Score = 36.2 bits (82), Expect = 0.45
 Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 7/76 (9%)

Query: 1452 CSDRCVEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNN 1510
            CS      C C PG   S    C+P   C C H  G     G  W +  C E C+C S  
Sbjct: 4956 CSSARASGCVCQPGHFRSQAGPCVPEDHCECWH-LGRPHLPGSEW-QEAC-ESCLCLSGR 5012

Query: 1511 RI---RCQPWRCRAQE 1523
             +    C P  C   E
Sbjct: 5013 PVCTQHCSPLTCAQGE 5028



 Score = 35.4 bits (80), Expect = 0.77
 Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 10/57 (17%)

Query: 1055 CPASCK--SPRPSCGPL---CREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGA 1106
            CP SC+  SP   C P    C+  C C  G L  D  C+  + C C      Y+PGA
Sbjct: 3542 CPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QYQPGA 3593



 Score = 35.4 bits (80), Expect = 0.77
 Identities = 29/115 (25%), Positives = 39/115 (33%), Gaps = 22/115 (19%)

Query: 1812 CPPGSSYSPCS--SPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC 1869
            CP G  Y  C     CP +C+ +     C     C E C C +G      +CV   +C C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSE-GCEEGCHCPEGTFQHRLACVQ--ECPC 3753

Query: 1870 T--------------DPAGSYHPVGE--RWYTENTCTRLCTCSVHNNITCFQSTC 1908
                           DP     P  E     T  T    C+C+ H  ++C    C
Sbjct: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCA-HGKLSCSLDDC 3807



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 35/142 (24%), Positives = 49/142 (34%), Gaps = 27/142 (19%)

Query: 1363 GPFETCLLHVKAASFFDS--CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPH 1420
            GP+E C +         S  C    C     Q   C+     T  C++AG          
Sbjct: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696

Query: 1421 FCPMACPPNSKYSLC--AKPCPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLECIPRS 1477
                 CP    Y  C   + CP +C      + C S+ C E C C  G     L C+   
Sbjct: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--Q 3749

Query: 1478 QCGCLHPAGSYFKVGERWYKPG 1499
            +C C+  A    ++G     PG
Sbjct: 3750 ECPCVLTAWLLQELGATIGDPG 3771



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 26/140 (18%)

Query: 2174 GGLYQALCQ--ALQAFGATCQSQGLKPPL---WRNSSFCPLECPAYSSYTNCLPSCSPSC 2228
            G  +Q  C   + QA   +C +Q   PP    W +          +S+++ C  SC P  
Sbjct: 4130 GSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSH----------WSAWSPCSHSCGPRG 4179

Query: 2229 WDLDGRCE--GAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSS 2286
                 R    G+  P    E    QP     +  C P    G +     S  LG SW+  
Sbjct: 4180 QQSRFRSSTSGSWAPECREEQSQSQP---CPQPSCPPLCLQGTR-----SRTLGDSWLQG 4231

Query: 2287 GCTEKCVCTGGAIQCGDFRC 2306
             C ++C CT   + C D  C
Sbjct: 4232 EC-QRCSCTPEGVICEDTEC 4250



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 32/115 (27%), Positives = 44/115 (38%), Gaps = 36/115 (31%)

Query: 1037 SRSSTERCP----PNAR------YESCA-CPASCK--SPRPSCGP---LCREGCVCNPG- 1079
            S   T+ CP    PNA       ++ CA CP +C   S + +C P       GC C  G 
Sbjct: 1795 STRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQ 1854

Query: 1080 FLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRV--ECQISQC 1132
             L S+  C+    C C  +   Y                 WPG R+  +CQ+  C
Sbjct: 1855 VLGSEGWCVWPRQCPCLVDGARY-----------------WPGQRIKADCQLCIC 1892



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 1480 GCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPW 1517
            GC H  G   +VGERW+   C+ +C C  N    C P+
Sbjct: 1966 GCEHQ-GQVHRVGERWHGGPCR-VCQCLHNLTAHCSPY 2001



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 20/68 (29%), Positives = 22/68 (32%), Gaps = 7/68 (10%)

Query: 1033 TTTTSRSSTERCPPNARYESC----ACPASCKSPRPSCGPL---CREGCVCNPGFLFSDN 1085
            T +T       CP    Y  C     CP SC       G     C EGC C  G      
Sbjct: 3686 TCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRL 3745

Query: 1086 HCIQASSC 1093
             C+Q   C
Sbjct: 3746 ACVQECPC 3753


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score =  265 bits (676), Expect = 6e-70
 Identities = 287/1220 (23%), Positives = 454/1220 (37%), Gaps = 232/1220 (19%)

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
            A     C+  GD HY TFDG +  F G C YV +  C +  +D  F V      RG +  
Sbjct: 727  AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYED--FNVQL---RRGLVGS 781

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
               +  V +    L +    G  V++NG R  LP   ++  + +  S + + +     L 
Sbjct: 782  RPVVTRVVIKAQGLVLEASNG-SVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLT 838

Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNN-NSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
              ++G     + +   Y  Q CGLCG++N   + ++    + +L    +Q G   KL   
Sbjct: 839  FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT--PLQFGNLQKLDGP 896

Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
            +E  C      P      +  D        L+ P   F++CH +V   +  A+C    C 
Sbjct: 897  TEQ-C----PDPLPLPAGNCTDEEGICHRTLLGPA--FAECHALVDSTAYLAACAQDLCR 949

Query: 1775 TKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
                 T  C +   Y+  CA AG  P  WR    CP  CP    +  C SPC DTCS+  
Sbjct: 950  CP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQ 1006

Query: 1834 NPRDCPKALPCAESCECQKGHI------LSGTSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
              + C     C + C C  G        ++ + C+PLGQC CT    +Y P      + N
Sbjct: 1007 RAQLCEDH--CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSP----GTSFN 1060

Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGV-GVCQLPGESHYVSFDGSN 1946
            T    CTCS                      GL +C+     G C + G +H  ++D   
Sbjct: 1061 TTCSSCTCS---------------------GGLWQCQDLPCPGTCSVQGGAHISTYDEKL 1099

Query: 1947 HSIPDACTLVLVKVCHPAMALPFFKISAKHEK-----EEGGTEAFRLHEVYIDIYDAQVT 2001
            + +   C+ VL K C  +     F + A+  K      E   +A  L    +D  D  + 
Sbjct: 1100 YDLHGDCSYVLSKKCADSS----FTVLAELRKCGLTDNENCLKAVTLS---LDGGDTAIR 1152

Query: 2002 LQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEI--EIPT 2059
            +Q    V +NS    LP +S         SS + +V   +G+Q+      L+++   +  
Sbjct: 1153 VQADGGVFLNSIYTQLP-LSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDP 1211

Query: 2060 TYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA 2119
             + G++CG+CGNFN  + D+    S  V  + + F N+WK +    + ++   D   +  
Sbjct: 1212 AHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSV 1271

Query: 2120 EQQENPSGNC-RAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
            E +      C R  D   A            +++C S I+  PF  +C    C       
Sbjct: 1272 ENENYARHWCSRLTDPNSA------------FSRCHSIINPKPFHSNCMFDTCNCERSED 1319

Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPL--ECPAYSSYTNCLPSCSPSCWDL---DG 2233
             LC AL ++   C ++G++   WR+         CP    Y   + +C P+C  L   D 
Sbjct: 1320 CLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADV 1379

Query: 2234 RCEGAKVP---------------SAC---------AEGCICQPGYVLSEDKCV------- 2262
             C  + VP                AC         A G +  PG V+ ++  V       
Sbjct: 1380 TCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGK 1439

Query: 2263 ----------------PRSQCGCKDAHGGSI---------PLGKSWVSSGCTEKCVCTGG 2297
                            P     C ++  G+           L     S+ C   CVC  G
Sbjct: 1440 LSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPG 1499

Query: 2298 AIQCGDFRCPSGSHCQ-------------LTSDNSNSNCVSDKSE--------QCSVYGD 2336
             +  G   C +   C              +  D +   C + + E         C  YGD
Sbjct: 1500 LVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGD 1559

Query: 2337 PRYLTFDGFSYRLQGRMTYVLIK----------TVDVLPEGVE------------PLLVE 2374
              ++TFDG  Y  +G   Y+L +          T  ++ E +              L VE
Sbjct: 1560 GHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVE 1619

Query: 2375 GR------------NKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPN 2422
             R            N+  P  +S+  ++ +  +  Y++ LQ G    V       P    
Sbjct: 1620 VRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKI 1679

Query: 2423 EHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
             ++ + L      ++    + VS+  + +  I L   Y+G V GLCGN+D N  ND    
Sbjct: 1680 RYMGIFL------VIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATR 1733

Query: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
            S ++  +   FGNSW++         P A+  ++                 C+      +
Sbjct: 1734 SRSVVGDALEFGNSWKLSPS-----CPDALAPKD----------------PCTANPFRKS 1772

Query: 2543 STQ-ACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILC 2601
              Q  C +L  P   FAAC   V    + E CV D C A D     E  C  ++ YA  C
Sbjct: 1773 WAQKQCSILHGP--TFAACRSQVDSTKYYEACVNDAC-ACDSGGDCECFCTAVAAYAQAC 1829

Query: 2602 QEAGAALAGWRDRTLCESPC 2621
             +AG  ++ WR    C   C
Sbjct: 1830 HDAGLCVS-WRTPDTCPLFC 1848



 Score =  254 bits (648), Expect = 1e-66
 Identities = 211/807 (26%), Positives = 327/807 (40%), Gaps = 88/807 (10%)

Query: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207
            +P      C  +GD HY TFDG  F F G C Y+ ++ C  + + F  V  +    G   
Sbjct: 725  NPAHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDF-NVQLRRGLVGSRP 783

Query: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267
            V  +++V +      +    G   L+ GQ+  LP     G+ +  SG ++++     L  
Sbjct: 784  V--VTRVVIKAQGLVLEASNGS-VLINGQREELP-YSRTGLLVEQSGDYIKVSIRLVLTF 839

Query: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
             W+G+    + +   Y+ + CGLCG+++G    +      +     +  GN  + D   +
Sbjct: 840  LWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTE 898

Query: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386
            Q C     + + +C           G C R +   GP F  C   V + ++  +C  D+C
Sbjct: 899  Q-CPDPLPLPAGNCTDE-------EGICHRTL--LGPAFAECHALVDSTAYLAACAQDLC 948

Query: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
                     C      +  C  AG   + WR P  CP  CP N ++  C  PC DTC + 
Sbjct: 949  RCPTCP---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNP 1005

Query: 1447 FSGMFCSDRCVEACECNPGFVLSGLE------CIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
                 C D CV+ C C PG   + L+      C+P  QC C H        G R Y PG 
Sbjct: 1006 QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH--------GGRTYSPGT 1057

Query: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH-AQGAATCTASGDPHYLTFDGALHH 1559
                 C S                C    G++ C       TC+  G  H  T+D  L+ 
Sbjct: 1058 SFNTTCSS----------------CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYD 1101

Query: 1560 FMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTV--FDLSISLLRGC 1617
              G C+YVL++ C     DS F V A     G     + +KAV +++   D +I +    
Sbjct: 1102 LHGDCSYVLSKKC----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADG 1157

Query: 1618 KVMLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVEVTV--PSSYGG 1674
             V LN     LP  L+   +T+   SS  +++ T  GLQ+      L++V V    ++ G
Sbjct: 1158 GVFLNSIYTQLP--LSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQG 1215

Query: 1675 QLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLP-------ESSEPGCFLVGGKPS 1727
            Q+CGLCGN+N N  DD       +          WK          S E  C L      
Sbjct: 1216 QMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSL------ 1269

Query: 1728 SCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQ 1787
            S +  + A  W   C+ L +P   FS+CH ++ P+   ++C+   C  +     LC +L 
Sbjct: 1270 SVENENYARHW---CSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALS 1326

Query: 1788 AYASLCAQAG-QAPAWRNR--TFCPMRCPPGSSYSPCSSPCPDTCSSINNPR-DCPKALP 1843
            +Y   CA  G Q   WR+   T     CP    Y+     C  TC  ++     C  +  
Sbjct: 1327 SYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFV 1386

Query: 1844 CAESCECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNIT 1902
              + C C  G  L+   +CVP  +C C    G+    GE  + E     +C+C+    ++
Sbjct: 1387 PVDGCTCPAGTFLNDAGACVPAQECPCY-AHGTVLAPGEVVHDEGA---VCSCT-GGKLS 1441

Query: 1903 CFQSTCKPNQICWALDGLLRCRASGVG 1929
            C  ++ + +  C A    L C  S  G
Sbjct: 1442 CLGASLQKSTGCAAPMVYLDCSNSSAG 1468



 Score =  221 bits (562), Expect = 1e-56
 Identities = 165/554 (29%), Positives = 246/554 (44%), Gaps = 56/554 (10%)

Query: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207
            +P      C  +G  HY TFDG  F F G C Y+ ++ CG + + F     +++E     
Sbjct: 73   NPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESA--- 129

Query: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267
               LS+V + +    + L KG   LV G  V LP   S GV +  S  + +++   GL +
Sbjct: 130  APTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQS-GVLIQQSSSYTKVEARLGLVL 187

Query: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
             W+ D  L + + + Y+ K CGLCG+++G      L L  +      E GN  + D D  
Sbjct: 188  MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSEL-LSHNTKLTPMEFGNLQKMD-DPT 245

Query: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386
            ++CQ    V  P  + S     +G G C  L+  HG  F  C+  V   S+ ++C  D+C
Sbjct: 246  EQCQ--DPVPEPPRNCS-----TGFGICEELL--HGQLFSGCVALVDVGSYLEACRQDLC 296

Query: 1387 GFQGLQHL--LCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
              +    L  +C  ++  +  C  AG   + WR P FCP  CP N +Y  C  PC DTC 
Sbjct: 297  FCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356

Query: 1445 SGFSGMFCSDRCVEACECNPGFVLSGL---ECIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501
            +      C D CV  C C  G VL  +    C+P S+C C++   +Y       Y   C 
Sbjct: 357  NQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAY--APGATYSTDCT 414

Query: 1502 ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFM 1561
              C C S  R  CQ   C                     TC+  G  H+ TFDG  +   
Sbjct: 415  N-CTC-SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVH 453

Query: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTV--FDLSISLLRGCKV 1619
            G C+YVLT+PC      S F V A     G     + +K+V +++      + +    +V
Sbjct: 454  GDCSYVLTKPC----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEV 509

Query: 1620 MLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQL 1676
             LN     LP+  +   VTI R S+  ++  T+ GLQ+       ++  + +     GQ 
Sbjct: 510  FLNQIYTQLPI--SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQT 567

Query: 1677 CGLCGNYNNNSLDD 1690
            CGLCGN+N+   DD
Sbjct: 568  CGLCGNFNSIQADD 581



 Score =  193 bits (490), Expect = 2e-48
 Identities = 162/597 (27%), Positives = 254/597 (42%), Gaps = 61/597 (10%)

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
            A     C+  G  HY TFDG +  F G C YV +  C +  +D    +  + E+    L 
Sbjct: 75   AHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS 134

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
               +K   V      I L +G  V++NGH V LP   +Q  V I+ SS+   +    GL 
Sbjct: 135  RVLMKVDGVV-----IQLTKG-SVLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLV 186

Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL-DDNLRPDRKLAGDSMQLGAAWKLPES 1714
            + ++    + + + + Y  + CGLCG++N   +  + L  + KL    M+ G   K+ + 
Sbjct: 187  LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDP 244

Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
            +E     V   P +C            C  L++ Q  FS C  +V   S   +C    C 
Sbjct: 245  TEQCQDPVPEPPRNCSTGFGI------CEELLHGQ-LFSGCVALVDVGSYLEACRQDLCF 297

Query: 1775 TKGDTTAL---CRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
             + DT  L   C +L  Y+  C  AG  P  WR   FCP +CP    Y  C SPC DTCS
Sbjct: 298  CE-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356

Query: 1831 SINNPRDCPKALPCAESCECQKGHILSG---TSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
            +  + R C     C   C C +G +L     T CVP+ +C C     +Y P G  + T+ 
Sbjct: 357  NQEHSRACED--HCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP-GATYSTD- 412

Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947
             CT  CTCS     +C +  C                    G C + G +H+ +FDG  +
Sbjct: 413  -CTN-CTCS-GGRWSCQEVPCP-------------------GTCSVLGGAHFSTFDGKQY 450

Query: 1948 SIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ--VTLQKG 2005
            ++   C+ VL K C  +     F + A+  +         L  V + +  AQ  V ++  
Sbjct: 451  TVHGDCSYVLTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKAS 506

Query: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD--GNHLLEIEIPTTYYG 2063
              V +N     LP IS       + S+ + I    +G+Q+         L +++     G
Sbjct: 507  GEVFLNQIYTQLP-ISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565

Query: 2064 KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAE 2120
            + CG+CGNFN  + D+    S  V  + + F N++K +   P+ ++   D   +  E
Sbjct: 566  QTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVE 622



 Score =  186 bits (473), Expect = 2e-46
 Identities = 164/566 (28%), Positives = 226/566 (39%), Gaps = 118/566 (20%)

Query: 1055 CPASCKSPRPSC-GPLCREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSP 1111
            C  SC +    C    C  GCVC PG L SD    CI    C C +N   Y+PG      
Sbjct: 1474 CLRSCHTLDVGCFSTHCVSGCVCPPG-LVSDGSGGCIAEEDCPCVHNEATYKPGET---- 1528

Query: 1112 NCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRH 1171
                        RV+C          C  +N ++ C       TC+ YGD H++TFDG  
Sbjct: 1529 -----------IRVDCN--------TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 1569

Query: 1172 FGFMGKCTYILAQP-CG-NSTDPFFRVTAKNEEQGQEGVSCLSKVY----------VTLP 1219
            + F G C YILAQ  CG N+T   FR+  +N   G  G +C   +           V+ P
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTP 1629

Query: 1220 ESTVTLLKGRRTLVGGQQVTLPAIPS------KGVFLGAS--------------GRFVEL 1259
            +        R   VG +Q  LP + S      +G F   +              G F+ +
Sbjct: 1630 DPAANEPAPREASVGFRQ-RLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVI 1688

Query: 1260 QTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNS 1319
            +T  G+ V WD    +++ +   Y G++CGLCGN+D N+ ND      S  GD  E GNS
Sbjct: 1689 ETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNS 1747

Query: 1320 WQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFF 1378
            W+        C        P   +  + S +    C  L   HGP F  C   V +  ++
Sbjct: 1748 WKL----SPSCPDALAPKDPCTANPFRKSWAQKQ-CSIL---HGPTFAACRSQVDSTKYY 1799

Query: 1379 DSCMLDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACP---PNS--- 1430
            ++C+ D C     G     CT ++     C DAG  V  WR P  CP+ C    P+    
Sbjct: 1800 EACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCE 1858

Query: 1431 -KYSLCAKPCPDTCHSGFSGMFCSDRCVEAC--ECNPG---FVLSGLECIPRSQCGCLHP 1484
              Y  C  PC  TC +           +E C  +C P    F    ++C+  +QCGC   
Sbjct: 1859 WHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDK 1916

Query: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT- 1543
             G+Y+ VG R   P  +    C+S N   C P             GI   H+  A TCT 
Sbjct: 1917 DGNYYDVGAR--VPTAEN---CQSCN---CTP------------SGIQCAHSLEACTCTY 1956

Query: 1544 -----ASGDPHYLTFDGALHHFMGTC 1564
                 +  D  Y T DG     +G C
Sbjct: 1957 EDRTYSYQDVIYNTTDG-----LGAC 1977



 Score =  180 bits (457), Expect = 1e-44
 Identities = 159/571 (27%), Positives = 226/571 (39%), Gaps = 96/571 (16%)

Query: 1429 NSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGS 1487
            NS        C  +CH+   G F S  CV  C C PG V  G   CI    C C+H    
Sbjct: 1464 NSSAGTPGAECLRSCHTLDVGCF-STHCVSGCVCPPGLVSDGSGGCIAEEDCPCVH---- 1518

Query: 1488 YFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEF-CGQQDGIYGCHAQGAATCTASG 1546
                 E  YKPG           R+ C    CR + + C         H     TC A G
Sbjct: 1519 ----NEATYKPG--------ETIRVDCNTCTCRNRRWECS--------HRLCLGTCVAYG 1558

Query: 1547 DPHYLTFDGALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGG-----------IL 1594
            D H++TFDG  + F G+C Y+L +  C   +    F +   N   G             +
Sbjct: 1559 DGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFV 1618

Query: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALP------VWLAQGRVT---------- 1638
            EV    AV       +    R   V   G R  LP      + L +G             
Sbjct: 1619 EVRTAPAVSTPDPAANEPAPREASV---GFRQRLPPLQSYELILQEGTFKAVARGPGGDP 1675

Query: 1639 ---IRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPD 1695
               IR     +++ T+ G+ V +D    V + +   Y G++CGLCGN+++N+++D     
Sbjct: 1676 PYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRS 1734

Query: 1696 RKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQ 1754
            R + GD+++ G +WKL     P C         C  N    +W  K C+IL  P   F+ 
Sbjct: 1735 RSVVGDALEFGNSWKL----SPSCPDALAPKDPCTANPFRKSWAQKQCSILHGP--TFAA 1788

Query: 1755 CHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
            C   V     + +CV+  C   + GD    C ++ AYA  C  AG   +WR    CP+ C
Sbjct: 1789 CRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFC 1848

Query: 1813 ----PPGS---SYSPCSSPCPDTCSSINNPRDCPKALPCAESC--ECQKGH-ILSGTSCV 1862
                P G     Y PC +PC  TC   N    C   LP  E C  +C       +     
Sbjct: 1849 DFYNPHGGCEWHYQPCGAPCLKTCR--NPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMK 1906

Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQS----TCKPNQICWALD 1918
             + QCGC D  G+Y+ VG R  T   C + C C+  + I C  S    TC      ++  
Sbjct: 1907 CVAQCGCYDKDGNYYDVGARVPTAENC-QSCNCT-PSGIQCAHSLEACTCTYEDRTYSYQ 1964

Query: 1919 GLLRCRASGVGVCQLPGESHYVSFDGSNHSI 1949
             ++     G+G C        ++  GSN +I
Sbjct: 1965 DVIYNTTDGLGAC-------LIAICGSNGTI 1988



 Score =  171 bits (432), Expect = 1e-41
 Identities = 155/586 (26%), Positives = 234/586 (39%), Gaps = 77/586 (13%)

Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
            VC   G  HY +FDG     P  C  V  + C    A   F I  +  +E     A  L 
Sbjct: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHC--GAAYEDFNIQLRRSQESA---APTLS 134

Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
             V + +    + L KG  VL+N   V LP  SQ  GV ++ SS Y+ V  ++G+ + ++ 
Sbjct: 135  RVLMKVDGVVIQLTKGS-VLVNGHPVLLP-FSQ-SGVLIQQSSSYTKVEARLGLVLMWNH 191

Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS 2109
            +  L +E+ T Y  K CG+CG+FN       ++ S     +  EF N  K  D    CQ 
Sbjct: 192  DDSLLLELDTKYANKTCGLCGDFNGMPVVSELL-SHNTKLTPMEFGNLQKMDDPTEQCQD 250

Query: 2110 LLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANT 2169
             + +           P  NC           CE  L   +++ C + +D+  +L  C   
Sbjct: 251  PVPE-----------PPRNCSTGF-----GICEELLHGQLFSGCVALVDVGSYLEACRQD 294

Query: 2170 LC--EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPS 2227
            LC  E   L   +C  L  +   C   G  P  WR   FCP +CP    Y  C   C+ +
Sbjct: 295  LCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADT 354

Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVL---SEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
            C + +           C  GC C  G VL    +  CVP S+C C   + G+     +  
Sbjct: 355  CSNQE---HSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCAC--VYNGAAYAPGATY 409

Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
            S+ CT  C C+GG   C +  CP                       CSV G   + TFDG
Sbjct: 410  STDCT-NCTCSGGRWSCQEVPCPG---------------------TCSVLGGAHFSTFDG 447

Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYK--VQL 2402
              Y + G  +YVL K  D        +L E R +     S   L+ V  ++ G +  V +
Sbjct: 448  KQYTVHGDCSYVLTKPCD---SSAFTVLAELR-RCGLTDSETCLKSVTLSLDGAQTVVVI 503

Query: 2403 QAGLELVVNNQKMAVP--------YRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI 2454
            +A  E+ +N     +P        +RP+    +      L L  + +LV +        +
Sbjct: 504  KASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQL--NLQLVPTM----QLFM 557

Query: 2455 SLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVK 2500
             L     G   GLCGN++  + +D    SG +      F N+++ +
Sbjct: 558  QLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQ 603



 Score =  168 bits (425), Expect = 8e-41
 Identities = 291/1110 (26%), Positives = 423/1110 (38%), Gaps = 153/1110 (13%)

Query: 531  PGTCPVKVLPELPPVSPVS-STG----PSETTGLTENPTISTKKPTVSIEKPSVTTEKPT 585
            PGT    +L EL   +  + STG    PS T G    P + T   T     P+ T+ K T
Sbjct: 4717 PGT--TWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT----PTATSSKAT 4770

Query: 586  V---PKEKPTIP--TEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTI-PSEK 639
                P+   T+P  T   T ST     P     + +   T+P +  T +    TI PS  
Sbjct: 4771 SSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTG-TLPEQTTTPVATMSTIHPSST 4829

Query: 640  P------TIPSEKPTIS--TEKPTVPTEEPTTP---TEETTTSMEEPVI-PTEKPSIPTE 687
            P      T+ + K T +  T   + P+  P T    TE TT +       PT  PS    
Sbjct: 4830 PETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPG 4889

Query: 688  KPSIPTEKPTISMEETII-STEKPTISPEKPTIPTEKPT-----IPT-EKSTISPEKPTT 740
               I TE  T +       ST  P+ +P    I TE  T     +PT   +T S  + T 
Sbjct: 4890 TTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATA 4949

Query: 741  PTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT-IPTEKPTIPTEKPTIPTEKPTIST- 798
             T   +     PT++  K T     P+ SP   T +P  + T  T   T  T  P+ S  
Sbjct: 4950 GTPHVSTTATTPTVTSSKAT-----PSSSPGTATALPALRSTATTPTATSFTAIPSSSLG 5004

Query: 799  ------EEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTI 852
                   + TTPT   T+ST  PS   E  T+ T    T+   TT +T  +  P   P  
Sbjct: 5005 TTWTRLSQTTTPT--ATMSTATPSSTPE--TVHTSTVLTATATTTGATGSVATPSSTPGT 5060

Query: 853  S--TEKPTIPTEKPTISPEKLTIPTEKLTIPTEKP-----TIPIEETTISTEKLTIPTEK 905
            +  T+ PT  T   T +P   + P   LT PT  P     TI    T  +T   T+ T  
Sbjct: 5061 AHTTKVPTTTTTGFTATPS--SSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTT 5118

Query: 906  PTISPEKPTISTEKPTIPTEKPTIPTE-ETTISTEKLTIPTEKPTISPEKLTIPTEKPTI 964
             T++    + +T   T+ T +  I TE  TT +T   T  T   + +P    I TE  TI
Sbjct: 5119 ATMTRATNSTATPSSTLGTTR--ILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTI 5176

Query: 965  STEK-PT--IPTEKLTIPT-EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020
            +T   PT    T   T+ T   P + T   T+PT   TA   P  S   T     V+   
Sbjct: 5177 ATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTA--TASTVPSSSTVGTTRTPAVLPSS 5234

Query: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYES-CACPASC-----------KSPRPSCG- 1067
             P+  +++V     TT R +     P++ + + C C A             K+ R  C  
Sbjct: 5235 LPTFSVSTVSSSVLTTLRPTGF---PSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHF 5291

Query: 1068 -PLCRE---------GCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
              +C +          C  +P  + S      + +  C       +    W   NCT   
Sbjct: 5292 YAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNETWTLENCTV-A 5350

Query: 1118 RCW-----------PGSRVEC-------QISQ----CGTHTVCQLKN-GQYGCHPYAGTA 1154
            RC            P + V C       ++S     C  H  C+ +  G  G  P AG  
Sbjct: 5351 RCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITPGAGI- 5409

Query: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC----GNST----DPFFRVTAKNEEQGQE 1206
             C ++G  HY TFDG  + F G CTY+L +      GN +    + +   +A        
Sbjct: 5410 -CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAAR 5468

Query: 1207 GVSCLSKVYVTLP-ESTVTLLKGRRT-LVGGQQVTLPAIPSK-GVF---LGASGRFVELQ 1260
                LS  Y ++    TVT++ G+   L+   Q+ + +  SK GV    LG +   V++ 
Sbjct: 5469 CPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIP 5528

Query: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
               G+ V ++G         S +     G CG    N  +D L+ DG+ A   +++  +W
Sbjct: 5529 A-LGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTW 5587

Query: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFC--GRLVD--THGPFETCLLHVKAAS 1376
                     C         +  ++  SS   P  C    L D      F  C   V    
Sbjct: 5588 LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGP 5647

Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWR--EPHFCPMACPPNSKYSL 1434
            FF++C+ D C  +G   + C  +      C+  G     WR      C + CPP   Y  
Sbjct: 5648 FFNACISDHC--RGRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKP 5704

Query: 1435 CAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLEC-IPRSQCGCLHPAGSYFKVGE 1493
            C    P TC+S        +   E C C    +L      I    C C+ P G     GE
Sbjct: 5705 CGPIQPATCNSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGE 5763

Query: 1494 RWYKPGCKELCVC-ESNNRIRCQPWRCRAQ 1522
            RW    C+  CVC E +  ++C+P  C AQ
Sbjct: 5764 RWVS-NCQS-CVCDEGSVSVQCKPLPCDAQ 5791



 Score =  153 bits (387), Expect = 2e-36
 Identities = 116/493 (23%), Positives = 197/493 (39%), Gaps = 57/493 (11%)

Query: 1044 CPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFL------FSDNHCIQASSC 1093
            CP N +++ C  P +  C +P+ +  C   C +GC C PG         + + C+    C
Sbjct: 985  CPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQC 1044

Query: 1094 NCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGT 1153
             C +    Y PG   F+  C+                       C    G + C      
Sbjct: 1045 PCTHGGRTYSPGTS-FNTTCSS----------------------CTCSGGLWQCQDLPCP 1081

Query: 1154 ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLS 1212
             TC V G  H  T+D + +   G C+Y+L++ C +S+   F V A+  + G  +  +CL 
Sbjct: 1082 GTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSS---FTVLAELRKCGLTDNENCLK 1138

Query: 1213 KVYVTLP--ESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLR--VR 1268
             V ++L   ++ + +       +      LP   +       S  F+ +QT  GL+  V+
Sbjct: 1139 AVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQ 1198

Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
                 Q++V +   + G++CGLCGN++ N  +D   L G          N+W+       
Sbjct: 1199 LVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKA----QA 1254

Query: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388
             C   +      C  S+++      +C RL D +  F  C   +    F  +CM D C  
Sbjct: 1255 ACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNC 1314

Query: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP---MACPPNSKYSLCAKPCPDTCHS 1445
            +  +  LC  +S+    C   G  +  WR+   C      CP + +Y+     C  TC  
Sbjct: 1315 ERSEDCLCAALSSYVHACAAKGVQLSDWRD-GVCTKYMQNCPKSQRYAYVVDACQPTCRG 1373

Query: 1446 -GFSGMFCSDRC--VEACECNPG-FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501
               + + CS     V+ C C  G F+     C+P  +C C +  G+    GE  +  G  
Sbjct: 1374 LSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC-YAHGTVLAPGEVVHDEGA- 1431

Query: 1502 ELCVCESNNRIRC 1514
             +C C +  ++ C
Sbjct: 1432 -VCSC-TGGKLSC 1442



 Score =  142 bits (357), Expect = 6e-33
 Identities = 135/549 (24%), Positives = 206/549 (37%), Gaps = 113/549 (20%)

Query: 1844 CAESCECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNIT 1902
            C   C C  G +  G+  C+    C C     +Y P GE   T       CTC  +    
Sbjct: 1490 CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKP-GE---TIRVDCNTCTCR-NRRWE 1544

Query: 1903 CFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVK-VC 1961
            C    C                   +G C   G+ H+++FDG  +S   +C  +L +  C
Sbjct: 1545 CSHRLC-------------------LGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 1585

Query: 1962 HPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVT------------------- 2001
                    F+I  ++      GT   +  ++++++  A                      
Sbjct: 1586 GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGF 1645

Query: 2002 ------LQKGHRVLINSKQVTLPAISQIPG----VSVKSSSIYSIVNIKIGVQVKFDGNH 2051
                  LQ    +L   ++ T  A+++ PG      ++   I+ ++    G+ V +D   
Sbjct: 1646 RQRLPPLQSYELIL---QEGTFKAVARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKT 1701

Query: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
             + I +   Y G+VCG+CGNF+D   ++    S  V     EF NSWK   + PSC   L
Sbjct: 1702 SVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWK---LSPSCPDAL 1758

Query: 2112 VDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPVWAQCASRIDLTPFLVDCAN- 2168
                         P   C A   R+  A+++C + L  P +A C S++D T +   C N 
Sbjct: 1759 A------------PKDPCTANPFRKSWAQKQC-SILHGPTFAACRSQVDSTKYYEACVND 1805

Query: 2169 -TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNC 2220
               C+ GG  +  C A+ A+   C   GL    WR    CPL C  Y+        Y  C
Sbjct: 1806 ACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPC 1864

Query: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCI-----CQPGYVLSEDKCVPRSQCGCKDAHGG 2275
               C  +C +  G C    V     EGC       QP +   + KCV  +QCGC D  G 
Sbjct: 1865 GAPCLKTCRNPSGHC---LVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGN 1919

Query: 2276 SIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYG 2335
               +G    ++   + C CT   IQC                +S   C     ++   Y 
Sbjct: 1920 YYDVGARVPTAENCQSCNCTPSGIQCA---------------HSLEACTCTYEDRTYSYQ 1964

Query: 2336 DPRYLTFDG 2344
            D  Y T DG
Sbjct: 1965 DVIYNTTDG 1973



 Score =  139 bits (350), Expect = 4e-32
 Identities = 130/493 (26%), Positives = 187/493 (37%), Gaps = 71/493 (14%)

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
            DR   AC  +P  V S     P    GC + A    +V E W    C  +  C  +NR+ 
Sbjct: 5302 DRFQGACPTSPPPVSSAPLSSPSPAPGCDN-AIPLRQVNETWTLENCT-VARCVGDNRVV 5359

Query: 1514 CQPWRCRAQEFCGQQ-------------DGIYGCHAQ---------GAATCTASGDPHYL 1551
                +  A   C  +             D  Y C  +         GA  C+  G  HY 
Sbjct: 5360 LLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITPGAGICSMWGGSHYS 5419

Query: 1552 TFDGALHHFMGTCTYVLTRPCWSR-------SQDSYFVVSATNENRGGILEVSYIKAVHV 1604
            TFDG  + F G CTYVL R   +R         + Y   SAT              ++H 
Sbjct: 5420 TFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASAT--AAAAAARCPRALSIHY 5477

Query: 1605 TVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLL-----------YTNFG 1653
               D+ +++      M++G    L +   Q  V+   S N VL+               G
Sbjct: 5478 KSMDIVLTV-----TMVHGKEEGL-ILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALG 5531

Query: 1654 LQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPE 1713
            + V ++G         S +     G CG   NN  DD L+ D   A     +   W +P+
Sbjct: 5532 VSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPD 5591

Query: 1714 SSEPGCFLVGGKPSSCQENSMADAW--------NKNCAILINPQGPFSQCHQVVPPQSSF 1765
            S + GC+   G P +    +   +            C ++++    F++CH +VPP   F
Sbjct: 5592 SRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--VFAECHNLVPPGPFF 5649

Query: 1766 ASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRT--FCPMRCPPGSSYSPCSS 1823
             +C+   C  +G     C+SL+AYA LC   G    WR  T   C + CPP   Y PC  
Sbjct: 5650 NACISDHC--RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGP 5707

Query: 1824 PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHPVGER 1882
              P TC+S N     P+    AE C C +  IL      + +  C C  P G     GER
Sbjct: 5708 IQPATCNSRN---QSPQLEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGER 5764

Query: 1883 WYTENTCTRLCTC 1895
            W +     + C C
Sbjct: 5765 WVSN---CQSCVC 5774



 Score =  119 bits (297), Expect = 5e-26
 Identities = 98/351 (27%), Positives = 144/351 (41%), Gaps = 56/351 (15%)

Query: 1042 ERCPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFLFSD---NHCIQASSCN 1094
            ++CP N +Y  C  P +  C +   S  C   C  GC C  G +  D     C+  S C 
Sbjct: 336  QKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA 395

Query: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154
            C YN   Y PGA  +S +CT +C C  G R  CQ   C                      
Sbjct: 396  CVYNGAAYAPGAT-YSTDCT-NCTC-SGGRWSCQEVPC--------------------PG 432

Query: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLSK 1213
            TC V G  H+ TFDG+ +   G C+Y+L +PC +S    F V A+    G  +  +CL  
Sbjct: 433  TCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA---FTVLAELRRCGLTDSETCLKS 489

Query: 1214 VYVTLP-ESTVTLLKGRRTLVGGQQVT-LPAIPSKGVFLGASGRFVELQTEFGLRVRWD- 1270
            V ++L    TV ++K    +   Q  T LP   +       S  F+  QT  GL++    
Sbjct: 490  VTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQL 549

Query: 1271 -GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQE 1329
                QL++ ++    G+ CGLCGN++    +D   L G          N+++T       
Sbjct: 550  VPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT----QAA 605

Query: 1330 CQKYQVVNSPSCDSSLQSS--MSGPGFCGRLV------------DTHGPFE 1366
            C   +      C  S++++  M  P  C  LV            +T GP E
Sbjct: 606  CPNIRNSFEDPCSLSVENAPRMGAPSACRTLVLALAAMLVVPQAETQGPVE 656



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 149/578 (25%), Positives = 208/578 (35%), Gaps = 61/578 (10%)

Query: 530  NPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKE 589
            N G CP    P     +  SST P  T  LTE  T +T   T        +T     P +
Sbjct: 3550 NYGHCPST--PATSSTATPSST-PGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPK 3606

Query: 590  KPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS--EKPTILTEKPTIPS----EKPTIP 643
              T     PT ++ K T  S  P   +  P + S   K T  +  P IPS       T+P
Sbjct: 3607 VLTSTATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSFTP-IPSFTLGTTGTLP 3664

Query: 644  SEKPTISTEKPTV-PTEEP-TTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME 701
             +  T      T+ P+  P TT T    T+       T   S P+  P        ++  
Sbjct: 3665 EQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTA 3724

Query: 702  ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKP-TISPEKPT 760
             T  +   PT +P      T   T P+  +T++    +T T   T  T     +     T
Sbjct: 3725 ATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTAT 3784

Query: 761  TPT-----EKPTISPEKLT-IPTEKPTIPTEKPTIPTEKPTIS-----TEEPTTPTEETT 809
            TPT       P+ SP   T +P  + T  T   T  T  P+ S     T    T T   T
Sbjct: 3785 TPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTAT 3844

Query: 810  ISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP--TISTEKPTIPTEKPTIS 867
            +ST  PS   E  T+ T    T+   TT +T  +  P   P    +T+ PT  T   T +
Sbjct: 3845 MSTATPSSTPE--TVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 3902

Query: 868  PEKLTIPTEKLTIPTEKPTIPIEETTISTEK--LTIPTEKPTISPEKPTISTEKPTIPTE 925
            P   + P   LT     P + I  TT  T +     P+  P  +     ++T   T+ T 
Sbjct: 3903 PS--SSPGTALT-----PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 3955

Query: 926  KPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKL---TIPTEK 982
                P+  T  S    T P    T +    ++P   P       T  T  +   T  TE 
Sbjct: 3956 SMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 4015

Query: 983  PTIPTEKPTIPT----EKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSR 1038
             T+ +  P   T        AL  PHPS   T       SP +P T       GT+ T+ 
Sbjct: 4016 STVTSHTPAATTSTTQHSTPALSSPHPSSRTT------ESPPSPGTTTPGHTRGTSRTTA 4069

Query: 1039 SSTERCPPNARYESCACPASCKSP------RPSCGPLC 1070
            ++T    P+    S   P+S  S          C P C
Sbjct: 4070 TAT----PSKTRTSTLLPSSPTSAPITTVVTTGCEPQC 4103



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 124/530 (23%), Positives = 195/530 (36%), Gaps = 84/530 (15%)

Query: 1825 CPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWY 1884
            C   C        CP + P   S        LS  S  P    GC D A     V E W 
Sbjct: 5295 CNQHCDIDRFQGACPTSPPPVSSAP------LSSPSPAP----GC-DNAIPLRQVNETWT 5343

Query: 1885 TENTCTRLCTCSVHN-----------NITCFQS-----TCKPNQICWALDGLLRCRAS-- 1926
             EN CT +  C   N           N+TC           P+Q C   D    C     
Sbjct: 5344 LEN-CT-VARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPC---DFHYECECECV 5398

Query: 1927 -------GVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHP-----AMALPFFKISA 1974
                   G G+C + G SHY +FDG++++    CT VL++  H      ++ L     +A
Sbjct: 5399 GGRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTA 5458

Query: 1975 KHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPG--------- 2025
                        R   ++    D  +T+      +++ K+  L    QIP          
Sbjct: 5459 SATAAAAAARCPRALSIHYKSMDIVLTV-----TMVHGKEEGLILFDQIPVSSGFSKNGV 5513

Query: 2026 -VSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIP-TTYYGKVCGMCGNFNDEEEDELMMP 2083
             VSV  ++   +    +GV V F+G  + +  +P + ++    G CG   + + D+ +  
Sbjct: 5514 LVSVLGTTTMRVDIPALGVSVTFNG-QVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQR 5572

Query: 2084 SDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEA 2143
                A S  +   +W     D             P      P  +         +  C+ 
Sbjct: 5573 DGTTAASCKDMAKTWLVP--DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDL 5630

Query: 2144 ALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRN 2203
             L + V+A+C + +   PF   C +  C   G  +  CQ+L+A+   C+++G+    WR 
Sbjct: 5631 ML-SQVFAECHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARGVCSD-WRG 5686

Query: 2204 SS--FCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDK- 2260
            ++   C L CP    Y  C P    +C   + R +  ++    AEGC C    +L     
Sbjct: 5687 ATGGLCDLTCPPTKVYKPCGPIQPATC---NSRNQSPQL-EGMAEGCFCPEDQILFNAHM 5742

Query: 2261 --CVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGG--AIQCGDFRC 2306
              CV    C C    G     G+ WVS+   + CVC  G  ++QC    C
Sbjct: 5743 GICV--QACPCVGPDGFPKFPGERWVSN--CQSCVCDEGSVSVQCKPLPC 5788



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 115/443 (25%), Positives = 164/443 (37%), Gaps = 81/443 (18%)

Query: 661  PTTPTEETTTSMEEPVIPTEKPS---IPTEKPSIPTEKPTISMEETIISTEKPTISPEKP 717
            P+TP   +T       +P+  P    I TE  +  T   +     T  ST      P+  
Sbjct: 4702 PSTPATSSTA------MPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVL 4755

Query: 718  TIPTEKPTIPTEKSTISPEKPTTPTEKPTI-------------PTEKPTIS-----PEKP 759
            T P   PT  + K+T S   P T T  P +             P    T+      PE+ 
Sbjct: 4756 TSPATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQT 4814

Query: 760  TTP-TEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTE-KPSI 817
            TTP     TI P      T   T+ T K T  T + T ST  P++    T I TE   + 
Sbjct: 4815 TTPVATMSTIHPSSTPETTHTSTVLTTKAT--TTRATSSTSTPSSTPGTTWILTELTTAA 4872

Query: 818  PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTE- 876
                 T PT   +++   T I TE  T      T +T   T  T  P+ +P    I TE 
Sbjct: 4873 TTTAATGPTATPSSTPGTTWILTELTT------TATTTASTGSTATPSSTPGTTWILTEP 4926

Query: 877  ----KLTIPT-EKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPT---IPTEKPT 928
                 +T+PT    T    + T  T  ++     PT++  K T S+   T   +P  + T
Sbjct: 4927 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRST 4986

Query: 929  IPTEETT-------------------ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
              T   T                    +T   T+ T  P+ +PE  T+ T     +T   
Sbjct: 4987 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE--TVHTSTVLTATATT 5044

Query: 970  TIPTEKLTIPTEKP--TIPTEKPTIPTEKL---------TALRPPHPSPTATGLAALVMS 1018
            T  T  +  P+  P     T+ PT  T            TAL PP  +P +T   + + +
Sbjct: 5045 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMST--MSTIHT 5102

Query: 1019 PHAPSTPMTSVILGTTTTSRSST 1041
               P T  TS +L TT T   +T
Sbjct: 5103 SSTPETTHTSTVLTTTATMTRAT 5125



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 135/533 (25%), Positives = 191/533 (35%), Gaps = 51/533 (9%)

Query: 549  SSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIP 608
            +S  P+ TTG T++ T +   P  S    S TTE P  P    T P      S    T  
Sbjct: 4521 TSHTPAATTGTTQHSTPALSSPHPS----SRTTESP--PSPGTTTPGHTTATSRTTATAT 4574

Query: 609  SEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEET 668
              K    +  P+ P+  P  +T   T   E     SE    S   P     +  T +   
Sbjct: 4575 PSKTRTSTLLPSSPTSAP--ITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 4632

Query: 669  TTSMEEPVIPTEKPSIPTEKPSIPT----EKPTISMEETIISTEKPTISPEKPTIPTEK- 723
                     P         +P +P     +    S++  ++   +  +   K     E  
Sbjct: 4633 AAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 4692

Query: 724  ---------PTIPTEKSTISPEKP--TTPTEKPTIPTEKPTISPEKPTTPTEKPTISP-- 770
                     P+ P   ST  P     TT        T   T S     TP+  P  +P  
Sbjct: 4693 VFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPP 4752

Query: 771  EKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETT 830
            + LT P   PT  + K T  +   T +T    T T   T ST     P+   TL T  T 
Sbjct: 4753 KVLTSPATTPTATSSKATSSSSPRTATTLPVLTST--ATKSTATSVTPIPSSTLGTTGTL 4810

Query: 831  TSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT---I 887
                 T ++T     P   P  +T   T+ T K T      T  T   + P+  P    I
Sbjct: 4811 PEQTTTPVATMSTIHPSSTPE-TTHTSTVLTTKATT-----TRATSSTSTPSSTPGTTWI 4864

Query: 888  PIEETTISTEKL-TIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT-IPT 945
              E TT +T    T PT  P+ +P    I TE  T  T   +  +  T  ST   T I T
Sbjct: 4865 LTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILT 4924

Query: 946  EKPTISPEKLTIPT-EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTE-----KLTA 999
            E  T +   +T+PT    T S+ + T  T  ++     PT+ + K T  +       L A
Sbjct: 4925 EPSTTA--TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPA 4982

Query: 1000 LRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYES 1052
            LR    +PTAT   A+  S    S   T   L  TTT  ++     P++  E+
Sbjct: 4983 LRSTATTPTATSFTAIPSS----SLGTTWTRLSQTTTPTATMSTATPSSTPET 5031



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 127/519 (24%), Positives = 183/519 (35%), Gaps = 79/519 (15%)

Query: 468  LLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFI 527
            +L S A +P     K   S  P    T+ T+P        L     + + T+      F 
Sbjct: 3607 VLTSTATTPTATSSKATSSSSP---RTATTLPV-------LTSTATKSTATSFTPIPSFT 3656

Query: 528  LINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTV-----SIEKPSVTTE 582
            L   GT P +      P++ +S+  PS T   T   T+ T K T      S+  PS T  
Sbjct: 3657 LGTTGTLPEQTTT---PMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPG 3713

Query: 583  KPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM------PSEKPTIP-------------- 622
               +  E  T  T   T +T     PS  P        PS   T+               
Sbjct: 3714 TTWILTELTTAATT--TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRA 3771

Query: 623  -----------SEKPTILTEKPTIPSEKP----TIPSEKPTISTEKPTVPTEEPTTPTEE 667
                       +  PT+++ + T PS  P     +P+ + T +T   T  T  P++    
Sbjct: 3772 TAGTLKVLTSTATTPTVISSRAT-PSSSPGTATALPALRSTATTPTATSVTAIPSSSLGT 3830

Query: 668  TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP------T 721
              T + +   PT   S  T   S P    T ++  T  +T + T S   P+        T
Sbjct: 3831 AWTRLSQTTTPTATMSTATPS-STPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTT 3889

Query: 722  EKPTIPTEKSTISPEK-PTTPTEKPT-IPTEKPTISPEKPTTPTEKPTISPEKLTIPTEK 779
            + PT  T   T +P   P T    P  I T     +     TP+  P  +     + T  
Sbjct: 3890 KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 3949

Query: 780  PTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKP-TLPTEET--TTSVEET 836
             T+ T     P+     S    T P   TT +T   S+P   P T+ T  T  T+ +  T
Sbjct: 3950 TTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGT 4009

Query: 837  TISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTIST 896
            T  TE  T+    P  +T   T     P +S      P+ + T     P       T  T
Sbjct: 4010 THITEPSTVTSHTPAATTS--TTQHSTPALSSPH---PSSRTTESPPSPGTTTPGHTRGT 4064

Query: 897  EKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETT 935
             + T      T +P K   ST  P+ PT  P I T  TT
Sbjct: 4065 SRTT-----ATATPSKTRTSTLLPSSPTSAP-ITTVVTT 4097



 Score = 79.0 bits (193), Expect = 6e-14
 Identities = 104/395 (26%), Positives = 151/395 (38%), Gaps = 39/395 (9%)

Query: 554  SETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT-EKPTISTEKPTIPSEKP 612
            +E+TG T  P+ ST   T  + +PS T    TV     T+PT    T S+ + T  +   
Sbjct: 4231 TESTGSTATPS-STPGTTWILTEPSTTA---TV-----TVPTGSTATASSTQATAGTPHV 4281

Query: 613  NMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSM 672
            +  +  PT+ S K T  +     P     +P+ + T +T   T  T  P++    T T +
Sbjct: 4282 STTATTPTVTSSKATPFSS----PGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRL 4337

Query: 673  EEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP------TEKPTI 726
             +   PT   S  T   S P    T ++  T  +T + T S   P+        T+ PT 
Sbjct: 4338 SQTTTPTATMSTATPS-STPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTT 4396

Query: 727  PTEKSTISPEKPTTPTEKPTI---PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP 783
             T   T++P         P +    T  PT S     TP+  P  +     + T   T+ 
Sbjct: 4397 TTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGST-VTPSSVPGTTHTPTVLTTTTTTVA 4455

Query: 784  TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL 843
            T     P+     S    T P   TT +T   S+    P        TS    T+ T  +
Sbjct: 4456 TGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHT-VRTAWTSATSGTLGTTHI 4514

Query: 844  TIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEET---TISTEKLT 900
            T P    T ++  P   T     S   L+ P    +  TE P  P   T   T +T + T
Sbjct: 4515 TEPS---TGTSHTPAATTGTTQHSTPALSSPHPS-SRTTESPPSPGTTTPGHTTATSRTT 4570

Query: 901  IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETT 935
                  T +P K   ST  P+ PT  P I T  TT
Sbjct: 4571 A-----TATPSKTRTSTLLPSSPTSAP-ITTVVTT 4599



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 102/403 (25%), Positives = 148/403 (36%), Gaps = 46/403 (11%)

Query: 689  PSIPTEKPTISMEET-----IISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTE 743
            PS P    T +   T     I++    T +    T  T  PT  T ++   P+  TT   
Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPT-STLRTAPPPKVLTTTAT 2637

Query: 744  KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
             PT+ + K T S   P T T  P +     T PT     P    ++ T    +S  + TT
Sbjct: 2638 TPTVTSSKATPS-SSPGTATALPALR-STATTPTATSVTPIPSSSLGTTWTRLS--QTTT 2693

Query: 804  PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP--TISTEKPTIPT 861
            PT   T+ST  PS   E  T  T    T+   TT +T  +  P   P    +T+ PT  T
Sbjct: 2694 PT--ATMSTATPSSTPE--TAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTT 2749

Query: 862  EKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEK--LTIPTEKPTISPEKPTISTEK 919
               T +P   + P   LT     P + I  TT  T +     P+  P  +     ++T  
Sbjct: 2750 TGFTATPS--SSPGTALT-----PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 2802

Query: 920  PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKP------TISTEKPTIPT 973
             T+ T     P+  T  S    T P      +    ++P   P        S     + T
Sbjct: 2803 TTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGT 2862

Query: 974  EKLTIPTEKPTIPTEKPTIPTEKLT-ALRPPHPSPTATGLAALVMSPHAPSTPMTSVILG 1032
              +T P+   +      T  T+  T AL  PHPS   T          +P +P T+    
Sbjct: 2863 THITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTT---------ESPPSPGTTTPGH 2913

Query: 1033 TTTTSRSSTERCPPNARYESCACPASCKSP-----RPSCGPLC 1070
            TT TSR++    P   R  +    +   +P        C P C
Sbjct: 2914 TTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQC 2956



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 107/397 (26%), Positives = 147/397 (37%), Gaps = 48/397 (12%)

Query: 682  PSIP-TEKPSIPTEKP-TISMEETIISTEKPTISPEKPTIPTEKP-TIPTEKSTISPEKP 738
            PS P T   ++P+  P T  +   + +T   T S      P+  P T P       P+  
Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPP------PKVL 4755

Query: 739  TTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST 798
            T+P   PT  + K T S   P T T  P      LT    K T  +  P   +   T  T
Sbjct: 4756 TSPATTPTATSSKAT-SSSSPRTATTLPV-----LTSTATKSTATSVTPIPSSTLGTTGT 4809

Query: 799  EEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP-------- 850
                T T   T+ST  PS   E  T  T    T+   TT +T   + P   P        
Sbjct: 4810 LPEQTTTPVATMSTIHPSSTPE--TTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTE 4867

Query: 851  ---TISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP- 906
                 +T   T PT  P+ +P    I TE  T  T   +     T  ST   T    +P 
Sbjct: 4868 LTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPS 4927

Query: 907  -TISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT-IPTEKPTI 964
             T +   PT ST   +        P   TT +T  +T     P+ SP   T +P  + T 
Sbjct: 4928 TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTA 4987

Query: 965  STEKPT----IPTEKL----------TIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTAT 1010
            +T   T    IP+  L          T PT   T+ T  P+   E +        + T T
Sbjct: 4988 TTPTATSFTAIPSSSLGTTWTRLSQTTTPT--ATMSTATPSSTPETVHTSTVLTATATTT 5045

Query: 1011 GLAALVMSPHA-PSTPMTSVILGTTTTSRSSTERCPP 1046
            G    V +P + P T  T+ +  TTTT  ++T    P
Sbjct: 5046 GATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSP 5082



 Score = 73.6 bits (179), Expect = 3e-12
 Identities = 106/417 (25%), Positives = 150/417 (35%), Gaps = 38/417 (9%)

Query: 530  NPGTCPVKVLPELPPVSPVSSTGPSETTGLTE-NPTISTKKPTVSIEKPSVTTEKPTVPK 588
            N G CP    P     +  SST P  T  LTE   T +T + T S   PS T     +  
Sbjct: 3048 NYGHCPST--PATSSTAMPSST-PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILT 3104

Query: 589  EKPT-----IPT-EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI 642
            E  T     +PT    T S+ + T  +   +  +  PT+ S K T  +     P     +
Sbjct: 3105 EPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSS----PGTATAL 3160

Query: 643  PSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEE 702
            P+ + T +T   T  T  P++    T T + +   PT   S  T     P+  P      
Sbjct: 3161 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT-----PSSTPETVHTS 3215

Query: 703  TIISTEKPTISPE-KPTIPTEKP-TIPTEK--STISPEKPTTPTEKPTIPTEKPTISPEK 758
            T+++T   T         P+  P T  T K  +T +     TP+  P      P      
Sbjct: 3216 TVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTT 3275

Query: 759  PTTPTEKPTISPEKLTIPTEKPTIPTEKPTI--------PTEKPTISTEEPTTPTEETTI 810
             T  T   T++P  +   T  PT+ T   T         P+     S    T P   TT 
Sbjct: 3276 TTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTA 3335

Query: 811  STEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK 870
            +T   S+    P        TS    T+ T  +T P    T ++  P   T     S   
Sbjct: 3336 TTHGRSLSPSSPHT-VRTAWTSATSGTLGTTHITEPS---TGTSHTPAATTGTTQHSTPA 3391

Query: 871  LTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927
            L+ P    +  TE P  P   T   T   +  T   T +P K   ST  P+ PT  P
Sbjct: 3392 LSSPHPS-SRTTESPPSPGTTTPGHTRATSRTTA--TATPSKTRTSTLLPSSPTSAP 3445



 Score = 72.4 bits (176), Expect = 6e-12
 Identities = 119/490 (24%), Positives = 175/490 (35%), Gaps = 53/490 (10%)

Query: 580  TTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEK 639
            TT  PT   E  T  T +   ST +PT     P +    P   +  PT L+E  T P   
Sbjct: 2301 TTPPPTTELETATTTTTQALFSTPQPT---SSPGLTRAPPASTTAVPT-LSEGLTSPRYT 2356

Query: 640  PTIPSEKPTISTEKPTVP--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697
             T+     T +T  PT P  + EPT P   T+T      +P    S+ T +PS P   PT
Sbjct: 2357 STL----GTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQP---PT 2409

Query: 698  ISMEETIISTEKPT----ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPT 753
            ++      S  +PT     + ++P   +  PT+ +E ST   E  T  TE         T
Sbjct: 2410 LAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTE--------TT 2461

Query: 754  ISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPT---------TP 804
            +SP   TT ++  T    K    TE      + PT       + T E            P
Sbjct: 2462 MSPLTNTTTSQGTTRCQPKCEW-TE--WFDVDFPTSGVAGGDMETFENIRAAGGKMCWAP 2518

Query: 805  TEETTISTEKPSIPMEKP----TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP 860
                  +   P + +++     T   E   T   E       +        +  +  +  
Sbjct: 2519 KSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHC 2578

Query: 861  TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920
               P  S       T   T    KPT     TT ST     PT     +P    ++T   
Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPT-TTATTTASTGSTATPTSTLRTAPPPKVLTTTAT 2637

Query: 921  TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLT 977
            T     PT+ + + T S+   T   +P  + T +    T  T  P+ S         + T
Sbjct: 2638 T-----PTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTT 2692

Query: 978  IPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHA-PSTPMTSVILGTTTT 1036
             PT   T+ T  P+   E          + T TG    V +P + P T  T+ +  TTTT
Sbjct: 2693 TPT--ATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTT 2750

Query: 1037 SRSSTERCPP 1046
              ++T    P
Sbjct: 2751 GFTATPSSSP 2760



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 99/396 (25%), Positives = 134/396 (33%), Gaps = 39/396 (9%)

Query: 540  PELPPVSPVSSTGPSETTGLT-----ENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIP 594
            P  P  S  S+  PS T G T        T +T   T S   P+ T      PK   T  
Sbjct: 2579 PSTPATS--STATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTA 2636

Query: 595  TEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKP 654
            T  PT+++ K T PS  P   +  P + S   T            PT  S  P  S+   
Sbjct: 2637 TT-PTVTSSKAT-PSSSPGTATALPALRSTATT------------PTATSVTPIPSSSLG 2682

Query: 655  TVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714
            T  T    T T   T S   P    E     T   +  T         T  ST     + 
Sbjct: 2683 TTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTT 2742

Query: 715  EKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774
            + PT  T   T     S  +   P       T PT + +       TP+  P  +     
Sbjct: 2743 KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGS-----TVTPSSIPGTTHTATV 2797

Query: 775  IPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKP-TLPTEET--TT 831
            + T   T+ T     P+     S    T P   T  +T   S+P   P T+ T  T  T+
Sbjct: 2798 LTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATS 2857

Query: 832  SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891
             +  TT  TE  T+     T++    T     P +S      P+ + T     P      
Sbjct: 2858 GILGTTHITEPSTVTSH--TLAATTGTTQHSTPALSSPH---PSSRTTESPPSPGTTTPG 2912

Query: 892  TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927
             T +T + T      T +P K   ST  P+ PT  P
Sbjct: 2913 HTTATSRTT-----ATATPSKTRTSTLLPSSPTSAP 2943



 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 92/366 (25%), Positives = 123/366 (33%), Gaps = 59/366 (16%)

Query: 549  SSTGPSETTG----LTENPTISTKK-PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE 603
            S+  PS T G    LTE  T +T   PT S    S T      P    T  T  PT+++ 
Sbjct: 4236 STATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT--PTVTSS 4293

Query: 604  KPTIPSEKPNMPSEKPTIPSEKPT-ILTEKPTIPSEK-------------PTIPSEKPTI 649
            K T P   P   +  P + S   T   T    IPS               PT      T 
Sbjct: 4294 KAT-PFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATP 4352

Query: 650  STEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP--TEKPSIPTEKPTISMEETIIST 707
            S+   T  T    T T  TT +      P+  P     T+ P+  T   T++   +  + 
Sbjct: 4353 SSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTA 4412

Query: 708  EKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKP 766
              P +     T PT      T  ST++P      T  PT+  T   T++     TP+   
Sbjct: 4413 RTPPVWISTTTTPT------TSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSST 4466

Query: 767  TISPEKLTIPTEKPTIPTEKPTIPTEKP----------------TISTEEPTTPTEETTI 810
              S    T P    T  T   ++    P                T    EP+T T  T  
Sbjct: 4467 QTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 4526

Query: 811  ST------EKPSIPMEKPTLPTEE------TTTSVEETTISTEKLTIPMEKPTISTEKPT 858
            +T        P++    P+  T E      TTT    T  S    T    K   ST  P+
Sbjct: 4527 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS 4586

Query: 859  IPTEKP 864
             PT  P
Sbjct: 4587 SPTSAP 4592



 Score = 65.1 bits (157), Expect = 9e-10
 Identities = 102/453 (22%), Positives = 159/453 (35%), Gaps = 92/453 (20%)

Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL---G 2280
            C+  C D+D R +GA         C   P  V S     P    GC +A    IPL    
Sbjct: 5295 CNQHC-DID-RFQGA---------CPTSPPPVSSAPLSSPSPAPGCDNA----IPLRQVN 5339

Query: 2281 KSWVSSGCTEK--------------------CVCTGGAIQCGDFRCPSGSHCQLTSDNSN 2320
            ++W    CT                      CV     I+  D   P   H +   +   
Sbjct: 5340 ETWTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVG 5399

Query: 2321 SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-------- 2372
               ++  +  CS++G   Y TFDG SY  +G  TYVL++ +      +   L        
Sbjct: 5400 GRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTAS 5459

Query: 2373 --VEGRNKMDPPRSSIFLQEV-----ITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL 2425
                      P   SI  + +     +T V+G +  L     ++ +   ++  +  N  L
Sbjct: 5460 ATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGL-----ILFDQIPVSSGFSKNGVL 5514

Query: 2426 RVTLWGQRLYL-VTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSG 2484
               L    + + +    + V+F G+        S++     G CG    N+++D +   G
Sbjct: 5515 VSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDG 5574

Query: 2485 ALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNST 2544
                +      +W V              + ++G  A  G  T    S  +P       T
Sbjct: 5575 TTAASCKDMAKTWLVPD------------SRKDGCWAPTG--TPPTASPAAPVSSTPTPT 5620

Query: 2545 QA-----CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAI 2599
                   C ++      FA CH  V P PF   C+ D C     R + E+ CQ L  YA 
Sbjct: 5621 PCPPQPLCDLMLSQV--FAECHNLVPPGPFFNACISDHC-----RGRLEVPCQSLEAYAE 5673

Query: 2600 LCQEAGAALAGWRDRT--LCESPC----LQNPC 2626
            LC+  G   + WR  T  LC+  C    +  PC
Sbjct: 5674 LCRARGVC-SDWRGATGGLCDLTCPPTKVYKPC 5705



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 129/569 (22%), Positives = 194/569 (34%), Gaps = 88/569 (15%)

Query: 546  SPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKP 605
            S V+S  P+ TT  T++ T +   P  S    S TTE P  P    T P      S    
Sbjct: 4016 STVTSHTPAATTSTTQHSTPALSSPHPS----SRTTESP--PSPGTTTPGHTRGTSRTTA 4069

Query: 606  TIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPT 665
            T    K    +  P+ P+  P  +T   T   E     SE    S   P     +  T +
Sbjct: 4070 TATPSKTRTSTLLPSSPTSAP--ITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYS 4127

Query: 666  EETTTSMEEPVIPTEKPSIPTEKPSIPTEK----PTISMEETIISTEKPTISPEKPTIPT 721
                        P         +P +P  +       S++  ++   +  +   K     
Sbjct: 4128 NIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNY 4187

Query: 722  EK----------PTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPE 771
            E           P+ P   ST +P   +TP     +     T +  + T  T  P+ +P 
Sbjct: 4188 EIRVFCCNYGHCPSTPATSSTATPS--STPGTTWILTKLTTTATTTESTGSTATPSSTPG 4245

Query: 772  KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTT 831
               I TE  T  T   T+PT          +T T  +T           + T  T   +T
Sbjct: 4246 TTWILTEPSTTATV--TVPTG---------STATASST-----------QATAGTPHVST 4283

Query: 832  SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT-IPTEKLTIPTEKPTIPIE 890
            +    T+++ K T P   P  +T  P + +   T +    T IP+  L     +    + 
Sbjct: 4284 TATTPTVTSSKAT-PFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTR----LS 4338

Query: 891  ETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTI 950
            +TT  T   T+ T  P+ +PE    ST   T  T      +  T  ST      T+ PT 
Sbjct: 4339 QTTTPTA--TMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTT 4396

Query: 951  SPEKLTI-PTEKP--------------TISTEKPTIPTEKLTIPTEKPTI-PTEKPTIPT 994
            +    T+ P+  P              T +T   T+    +   T  PT+  T   T+ T
Sbjct: 4397 TTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVAT 4456

Query: 995  EKL-----------TALRPPHPSPTAT--GLAALVMSPHAPSTPMTSVILGTTTTSR--- 1038
              +           T   PP P+ TAT  G +    SPH   T  TS   GT  T+    
Sbjct: 4457 GSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITE 4516

Query: 1039 --SSTERCPPNARYESCACPASCKSPRPS 1065
              + T   P      +     +  SP PS
Sbjct: 4517 PSTGTSHTPAATTGTTQHSTPALSSPHPS 4545



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 80/325 (24%), Positives = 113/325 (34%), Gaps = 49/325 (15%)

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
            CS +GD  Y TFDG  +R  G   YV  +      E     L  G     P      +  
Sbjct: 733  CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP-----VVTR 787

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSF--GG 2448
            V+    G  ++   G  +++N Q+  +PY     L V   G   Y+     LV++F   G
Sbjct: 788  VVIKAQGLVLEASNG-SVLINGQREELPY-SRTGLLVEQSGD--YIKVSIRLVLTFLWNG 843

Query: 2449 RKNAVISLPSMYEGLVSGLCGNYD-KNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLR 2507
              +A++ L   Y     GLCG+++     N+    +  LT     FGN  ++        
Sbjct: 844  EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKLDGPTEQCP 901

Query: 2508 FPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPE 2567
             P  +PA                   C+ E+   +     R L  P   FA CH  V   
Sbjct: 902  DPLPLPA-----------------GNCTDEEGICH-----RTLLGP--AFAECHALVDST 937

Query: 2568 PFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQ 2627
             +   C  DLC            C     Y+  C  AG     WR   LC   C  N   
Sbjct: 938  AYLAACAQDLCRC------PTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNM-- 989

Query: 2628 NDGQCREQGATFTCECEVGYGGGLC 2652
               Q +E G+  T  C       LC
Sbjct: 990  ---QHQECGSPCTDTCSNPQRAQLC 1011



 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 76/324 (23%), Positives = 112/324 (34%), Gaps = 51/324 (15%)

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
            CS +G   Y TFDG  +R  G   YV  +      E     L   +    P      L  
Sbjct: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPT-----LSR 135

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRK 2450
            V+  V G  +QL  G  ++VN   + +P+  +  L +        +     LV+ +    
Sbjct: 136  VLMKVDGVVIQLTKG-SVLVNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLVLMWNHDD 193

Query: 2451 NAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNT----FGNSWEVKTEDALL 2506
            + ++ L + Y     GLCG++     N M + S  L+ N       FGN    K +D   
Sbjct: 194  SLLLELDTKYANKTCGLCGDF-----NGMPVVSELLSHNTKLTPMEFGNLQ--KMDDPTE 246

Query: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAP 2566
            +    +P                      P +  S     C  L   Q  F+ C   V  
Sbjct: 247  QCQDPVP---------------------EPPRNCSTGFGICEELLHGQ-LFSGCVALVDV 284

Query: 2567 EPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQN-- 2624
              + E C  DLC  +D  +     C  L+ Y+  C  AG     WR    C   C  N  
Sbjct: 285  GSYLEACRQDLCFCED-TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQ 343

Query: 2625 ------PCQNDGQCREQGATFTCE 2642
                  PC +   C  Q  +  CE
Sbjct: 344  YHECRSPCAD--TCSNQEHSRACE 365



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 92/360 (25%), Positives = 130/360 (36%), Gaps = 64/360 (17%)

Query: 756  PEKP-TTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEK 814
            P  P T+ T  P+ +P    I TE  T  T      T + T ST  P++    T I TE 
Sbjct: 3053 PSTPATSSTAMPSSTPGTTWILTELTTTAT------TTESTGSTATPSSTPGTTWILTEP 3106

Query: 815  PSIPMEKPTLPTEETTT-SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT- 872
             +      T+PT  T T S  + T  T  ++     PT+++ K T     P  SP   T 
Sbjct: 3107 STTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-----PFSSPGTATA 3159

Query: 873  IPTEKLTIPTEKPT----IPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPT 928
            +P  + T  T   T    IP      +  +L+  T  PT +    T S+   T+ T    
Sbjct: 3160 LPALRSTATTPTATSFTAIPSSSLGTTWTRLS-QTTTPTATMSTATPSSTPETVHTSTVL 3218

Query: 929  IPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP-----TEKP 983
              T  TT +T  +  P+  P  +     + T     +    + P    T+P     T  P
Sbjct: 3219 TTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTP 3278

Query: 984  T----------IP--TEKPTIPTEKLTAL-------------------RPPHPSPTAT-- 1010
            T          IP  T  PT+ T   T +                    PP P+ TAT  
Sbjct: 3279 TTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTH 3338

Query: 1011 GLAALVMSPHAPSTPMTSVILGTTTTSR-----SSTERCPPNARYESCACPASCKSPRPS 1065
            G +    SPH   T  TS   GT  T+      + T   P      +     +  SP PS
Sbjct: 3339 GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPS 3398



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 131/551 (23%), Positives = 184/551 (33%), Gaps = 69/551 (12%)

Query: 530  NPGTCPVKVLPEL-----PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKP 584
            +PGT     LP L      P +   +  PS + G T      T  PT ++   + ++   
Sbjct: 4300 SPGTATA--LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE 4357

Query: 585  TVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPS 644
            T         T   T +T     PS  P          ++ PT  T   T+       PS
Sbjct: 4358 TAHTSTVLTTTATTTRATGSVATPSSTPGTAHT-----TKVPTTTTTGFTVT------PS 4406

Query: 645  EKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
              P  +    T P    TT T  T+ S   P         PT   +  T   T SM    
Sbjct: 4407 SSPGTAR---TPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPS 4463

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-------------TTPTEKPTIPTEK 751
             ST+    S    T P    T  T   ++SP  P             T  T   T P+  
Sbjct: 4464 SSTQ---TSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTG 4520

Query: 752  PTISPEKPTTPTEKPT---ISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEET 808
             + +P   T  T+  T    SP   +  TE P  P+   T P      S    T    +T
Sbjct: 4521 TSHTPAATTGTTQHSTPALSSPHPSSRTTESP--PSPGTTTPGHTTATSRTTATATPSKT 4578

Query: 809  TISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL--TIPMEKPTIS--TEKPTIPTEKP 864
              ST  PS P   P   T   TT  E     +E L  + PM  P+         I     
Sbjct: 4579 RTSTLLPSSPTSAPI--TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGG 4636

Query: 865  TISPEKLTIPTEKLTIPTEKPTIPIEE----TTISTEKLTIPTEKPTISPEKPTISTE-- 918
             +  + L +          +P +P+ E       S +   +   +  +   K   + E  
Sbjct: 4637 AVCEQPLGLECR----AQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 4692

Query: 919  --------KPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPT 970
                     P+ P    T     T  +T  LT  T   T +    T  T  P+ ST    
Sbjct: 4693 VFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTAS--TGSTATPS-STPGTA 4749

Query: 971  IPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVI 1030
             P + LT P   PT  + K T  +   TA   P  + TAT   A  ++P   ST  T+  
Sbjct: 4750 PPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4809

Query: 1031 LGTTTTSRSST 1041
            L   TT+  +T
Sbjct: 4810 LPEQTTTPVAT 4820



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 15/177 (8%)

Query: 543  PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPK--EKPTIPTEKPTI 600
            PP + + +   + T  L   P   T  P ++   P+ TT  PT+ +    P   +   T 
Sbjct: 2304 PPTTELETATTTTTQALFSTPQ-PTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTA 2362

Query: 601  STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI----PSEKPTISTEKPTV 656
            +T  PT P+      S +PT+P    + L  +  +P    ++    PS+ PT++   PT 
Sbjct: 2363 TTGGPTTPAG-----STEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLA---PTT 2414

Query: 657  PTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
                   PT   +T+ +EP+  +  P++ +E  +   E  T   E T+      T S
Sbjct: 2415 MATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTS 2471



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 53/189 (28%), Positives = 76/189 (40%), Gaps = 27/189 (14%)

Query: 882  TEKPTIPIEETTISTEKLTIPTEKPTISP----EKPTISTEKPTIPTEKPTIPTEETTIS 937
            T  PT  +E  T +T +    T +PT SP      P  +T  PT+ +E  T P   +T+ 
Sbjct: 2302 TPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTL-SEGLTSPRYTSTLG 2360

Query: 938  TEKLTIPT-----EKPTIS-------PEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985
            T     PT      +PT+        P +  +P    ++ T +P+ P      PT  PT 
Sbjct: 2361 TATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQP------PTLAPTT 2414

Query: 986  PTEKPTIPT-EKLTALRPPHPSPTATGLAA-LVMSPHAPSTPMTSVILG--TTTTSRSST 1041
                   PT    TA + P  +  A  L + L  S    STP T   +   T TT+   T
Sbjct: 2415 MATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGT 2474

Query: 1042 ERCPPNARY 1050
             RC P   +
Sbjct: 2475 TRCQPKCEW 2483



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 95/433 (21%), Positives = 140/433 (32%), Gaps = 57/433 (13%)

Query: 759  PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTI----STEEPTTPTEETTIS--- 811
            P  P+  P  SP+     + +P +PT   T  TEK T+    S       T +T  S   
Sbjct: 2124 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGP 2183

Query: 812  -TEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEK-PTISTEKPTIPTEKPTISPE 869
             T  PS P      P  + T   +E    +E+L   +E    I      +  +   I  +
Sbjct: 2184 VTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQ 2243

Query: 870  KLTIPTEKLTIPTEKPTIPI---------EETTISTEKLTIPTEKPTISPE--KPTISTE 918
              + P   L    +K    +         E+  +              S +  +   +T 
Sbjct: 2244 AESFPNWTLAQVGQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTP 2303

Query: 919  KPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTIS--TEKPTIPTEKL 976
             PT   E  T  T +   ST +   PT  P ++       T  PT+S     P   +   
Sbjct: 2304 PPTTELETATTTTTQALFSTPQ---PTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLG 2360

Query: 977  TIPTEKPTIP--TEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH----APSTPMTSVI 1030
            T  T  PT P  + +PT+P    + L      P  TG             AP+T  TS  
Sbjct: 2361 TATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRA 2420

Query: 1031 LGTTTTSRSS----TERCPPNARYESCACPASCKSPR--PSCGPLCREGCVCNPGFLFSD 1084
              T T S +S    T    P    E     A   +PR   +  PL       N       
Sbjct: 2421 RPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPL------TNTTTSQGT 2474

Query: 1085 NHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCR------CWPGSRVECQ--------IS 1130
              C        +++ D+   G         E+ R      CW    +EC+        I 
Sbjct: 2475 TRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSID 2534

Query: 1131 QCGTHTVCQLKNG 1143
            Q G    C L+ G
Sbjct: 2535 QVGQVLTCSLETG 2547



 Score = 42.0 bits (97), Expect = 0.008
 Identities = 48/206 (23%), Positives = 66/206 (32%), Gaps = 9/206 (4%)

Query: 531  PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEK 590
            PGT     +P        ++   S  T LT    IST     +       +  P      
Sbjct: 2736 PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTA 2795

Query: 591  PTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650
              + T   T++T     PS          T P       T   ++P   P       T +
Sbjct: 2796 TVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSA 2855

Query: 651  TE--KPTVPTEEPTTPTEET------TTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEE 702
            T     T    EP+T T  T      TT    P + +  PS  T + S P+   T     
Sbjct: 2856 TSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTE-SPPSPGTTTPGHT 2914

Query: 703  TIISTEKPTISPEKPTIPTEKPTIPT 728
            T  S    T +P K    T  P+ PT
Sbjct: 2915 TATSRTTATATPSKTRTSTLLPSSPT 2940



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 654  PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSI---PTEKPTISMEETIISTEKP 710
            P  P+  P T  + + ++  EP +PT   +  TEK ++   P+ + T ++     S+  P
Sbjct: 2124 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGP 2183

Query: 711  -TISPEKPTIPTEKP 724
             T++P  P   T +P
Sbjct: 2184 VTVTPSAPGTTTCQP 2198



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 30/115 (26%), Positives = 35/115 (30%), Gaps = 18/115 (15%)

Query: 1033 TTTTSRSSTERCPPNARYESCAC-PASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQAS 1091
            T T  R+    CP       C C   +C    P C P     C    G       C    
Sbjct: 5804 TVTRPRAENPCCPETV----CVCNTTTCPQSLPVCPPGQESICTQEEG------DCCPTF 5853

Query: 1092 SCN---CFYNNDYYEPGAEWFSPNCTEHCRCWPGS----RVECQISQCGTHTVCQ 1139
             C    C YN  +Y  GA +        C C  G      V+CQ   C   T  Q
Sbjct: 5854 RCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQ 5908


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score =  264 bits (675), Expect = 8e-70
 Identities = 283/1188 (23%), Positives = 445/1188 (37%), Gaps = 202/1188 (17%)

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
            A     C+  GD HY TFDG +  F G C YV +  C +  +D  F V      RG +  
Sbjct: 71   AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYED--FNVQL---RRGLVGS 125

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
               +  V +    L +    G  V++NG R  LP   ++  + +  S + + +     L 
Sbjct: 126  RPVVTRVVIKAQGLVLEASNG-SVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLT 182

Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNN-NSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
              ++G     + +   Y  Q CGLCG++N   + ++    + +L    +Q G   KL   
Sbjct: 183  FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT--PLQFGNLQKLDGP 240

Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
            +E  C      P      +  D        L+ P   F++CH +V   +  A+C    C 
Sbjct: 241  TEQ-C----PDPLPLPAGNCTDEEGICHRTLLGPA--FAECHALVDSTAYLAACAQDLCR 293

Query: 1775 TKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
                 T  C +   Y+  CA AG  P  WR    CP  CP    +  C SPC DTCS+  
Sbjct: 294  CP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQ 350

Query: 1834 NPRDCPKALPCAESCECQKGHI------LSGTSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
              + C     C + C C  G        ++ + C+PLGQC CT    +Y P      + N
Sbjct: 351  RAQLCEDH--CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSP----GTSFN 404

Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGV-GVCQLPGESHYVSFDGSN 1946
            T    CTCS                      GL +C+     G C + G +H  ++D   
Sbjct: 405  TTCSSCTCS---------------------GGLWQCQDLPCPGTCSVQGGAHISTYDEKL 443

Query: 1947 HSIPDACTLVLVKVCHPAMALPFFKISAKHEK-----EEGGTEAFRLHEVYIDIYDAQVT 2001
            + +   C+ VL K C  +     F + A+  K      E   +A  L    +D  D  + 
Sbjct: 444  YDLHGDCSYVLSKKCADSS----FTVLAELRKCGLTDNENCLKAVTLS---LDGGDTAIR 496

Query: 2002 LQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEI--EIPT 2059
            +Q    V +NS    LP +S         SS + +V   +G+Q+      L+++   +  
Sbjct: 497  VQADGGVFLNSIYTQLP-LSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDP 555

Query: 2060 TYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA 2119
             + G++CG+CGNFN  + D+    S  V  + + F N+WK +    + ++   D   +  
Sbjct: 556  AHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSV 615

Query: 2120 EQQENPSGNC-RAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
            E +      C R  D   A            +++C S I+  PF  +C    C       
Sbjct: 616  ENENYARHWCSRLTDPNSA------------FSRCHSIINPKPFHSNCMFDTCNCERSED 663

Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPL--ECPAYSSYTNCLPSCSPSCWDL---DG 2233
             LC AL ++   C ++G++   WR+         CP    Y   + +C P+C  L   D 
Sbjct: 664  CLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADV 723

Query: 2234 RCEGAKVP---------------SAC---------AEGCICQPGYVLSEDKCV------- 2262
             C  + VP                AC         A G +  PG V+ ++  V       
Sbjct: 724  TCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGK 783

Query: 2263 ----------------PRSQCGCKDAHGGSI---------PLGKSWVSSGCTEKCVCTGG 2297
                            P     C ++  G+           L     S+ C   CVC  G
Sbjct: 784  LSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPG 843

Query: 2298 AIQCGDFRCPSGSHCQ-------------LTSDNSNSNCVSDKSE--------QCSVYGD 2336
             +  G   C +   C              +  D +   C + + E         C  YGD
Sbjct: 844  LVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGD 903

Query: 2337 PRYLTFDGFSYRLQGRMTYVLIKTV--DVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT 2394
              ++TFDG  Y  +G   Y+L +    D    G   ++ E  N       +   + +   
Sbjct: 904  GHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTE--NIPCGTTGTTCSKAIKLF 961

Query: 2395 VYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI 2454
            V  Y++ LQ G    V       P     ++ + L      ++    + VS+  + +  I
Sbjct: 962  VESYELILQEGTFKAVARGPGGDPPYKIRYMGIFL------VIETHGMAVSWDRKTSVFI 1015

Query: 2455 SLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPA 2514
             L   Y+G V GLCGN+D N  ND    S ++  +   FGNSW++         P A+  
Sbjct: 1016 RLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPS-----CPDALAP 1070

Query: 2515 EEEGQGAELGLRTGLQVSECSPEQLASNSTQ-ACRVLADPQGPFAACHQTVAPEPFQEHC 2573
            ++                 C+      +  Q  C +L  P   FAAC   V    + E C
Sbjct: 1071 KD----------------PCTANPFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYEAC 1112

Query: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            V D C A D     E  C  ++ YA  C +AG  ++ WR    C   C
Sbjct: 1113 VNDAC-ACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFC 1158



 Score =  254 bits (648), Expect = 1e-66
 Identities = 211/807 (26%), Positives = 327/807 (40%), Gaps = 88/807 (10%)

Query: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207
            +P      C  +GD HY TFDG  F F G C Y+ ++ C  + + F  V  +    G   
Sbjct: 69   NPAHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDF-NVQLRRGLVGSRP 127

Query: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267
            V  +++V +      +    G   L+ GQ+  LP     G+ +  SG ++++     L  
Sbjct: 128  V--VTRVVIKAQGLVLEASNGS-VLINGQREELP-YSRTGLLVEQSGDYIKVSIRLVLTF 183

Query: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
             W+G+    + +   Y+ + CGLCG+++G    +      +     +  GN  + D   +
Sbjct: 184  LWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTE 242

Query: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386
            Q C     + + +C           G C R +   GP F  C   V + ++  +C  D+C
Sbjct: 243  Q-CPDPLPLPAGNCTDE-------EGICHRTL--LGPAFAECHALVDSTAYLAACAQDLC 292

Query: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
                     C      +  C  AG   + WR P  CP  CP N ++  C  PC DTC + 
Sbjct: 293  RCPTCP---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNP 349

Query: 1447 FSGMFCSDRCVEACECNPGFVLSGLE------CIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
                 C D CV+ C C PG   + L+      C+P  QC C H        G R Y PG 
Sbjct: 350  QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH--------GGRTYSPGT 401

Query: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH-AQGAATCTASGDPHYLTFDGALHH 1559
                 C S                C    G++ C       TC+  G  H  T+D  L+ 
Sbjct: 402  SFNTTCSS----------------CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYD 445

Query: 1560 FMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTV--FDLSISLLRGC 1617
              G C+YVL++ C     DS F V A     G     + +KAV +++   D +I +    
Sbjct: 446  LHGDCSYVLSKKC----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADG 501

Query: 1618 KVMLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVEVTV--PSSYGG 1674
             V LN     LP  L+   +T+   SS  +++ T  GLQ+      L++V V    ++ G
Sbjct: 502  GVFLNSIYTQLP--LSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQG 559

Query: 1675 QLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLP-------ESSEPGCFLVGGKPS 1727
            Q+CGLCGN+N N  DD       +          WK          S E  C L      
Sbjct: 560  QMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSL------ 613

Query: 1728 SCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQ 1787
            S +  + A  W   C+ L +P   FS+CH ++ P+   ++C+   C  +     LC +L 
Sbjct: 614  SVENENYARHW---CSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALS 670

Query: 1788 AYASLCAQAG-QAPAWRNR--TFCPMRCPPGSSYSPCSSPCPDTCSSINNPR-DCPKALP 1843
            +Y   CA  G Q   WR+   T     CP    Y+     C  TC  ++     C  +  
Sbjct: 671  SYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFV 730

Query: 1844 CAESCECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNIT 1902
              + C C  G  L+   +CVP  +C C    G+    GE  + E     +C+C+    ++
Sbjct: 731  PVDGCTCPAGTFLNDAGACVPAQECPCY-AHGTVLAPGEVVHDEGA---VCSCT-GGKLS 785

Query: 1903 CFQSTCKPNQICWALDGLLRCRASGVG 1929
            C  ++ + +  C A    L C  S  G
Sbjct: 786  CLGASLQKSTGCAAPMVYLDCSNSSAG 812



 Score =  191 bits (485), Expect = 8e-48
 Identities = 155/542 (28%), Positives = 223/542 (41%), Gaps = 72/542 (13%)

Query: 1429 NSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGS 1487
            NS        C  +CH+   G F S  CV  C C PG V  G   CI    C C+H    
Sbjct: 808  NSSAGTPGAECLRSCHTLDVGCF-STHCVSGCVCPPGLVSDGSGGCIAEEDCPCVH---- 862

Query: 1488 YFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEF-CGQQDGIYGCHAQGAATCTASG 1546
                 E  YKPG           R+ C    CR + + C         H     TC A G
Sbjct: 863  ----NEATYKPG--------ETIRVDCNTCTCRNRRWECS--------HRLCLGTCVAYG 902

Query: 1547 DPHYLTFDGALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT 1605
            D H++TFDG  + F G+C Y+L +  C   +    F +  T     G    +  KA+ + 
Sbjct: 903  DGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRI-VTENIPCGTTGTTCSKAIKLF 961

Query: 1606 VFDLSISLLRGC-KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLV 1664
            V    + L  G  K +  G     P         IR     +++ T+ G+ V +D    V
Sbjct: 962  VESYELILQEGTFKAVARGPGGDPPY-------KIRYMGIFLVIETH-GMAVSWDRKTSV 1013

Query: 1665 EVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG 1724
             + +   Y G++CGLCGN+++N+++D     R + GD+++ G +WKL     P C     
Sbjct: 1014 FIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKL----SPSCPDALA 1069

Query: 1725 KPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTA 1781
                C  N    +W  K C+IL  P   F+ C   V     + +CV+  C   + GD   
Sbjct: 1070 PKDPCTANPFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYEACVNDACACDSGGDCEC 1127

Query: 1782 LCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINN 1834
             C ++ AYA  C  AG   +WR    CP+ C    P G     Y PC +PC  TC   N 
Sbjct: 1128 FCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCR--NP 1185

Query: 1835 PRDCPKALPCAESC--ECQKGH-ILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTR 1891
               C   LP  E C  +C       +      + QCGC D  G+Y+ VG R  T   C +
Sbjct: 1186 SGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENC-Q 1244

Query: 1892 LCTCSVHNNITCFQS----TCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947
             C C+  + I C  S    TC      ++   ++     G+G C        ++  GSN 
Sbjct: 1245 SCNCT-PSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGAC-------LIAICGSNG 1296

Query: 1948 SI 1949
            +I
Sbjct: 1297 TI 1298



 Score =  190 bits (482), Expect = 2e-47
 Identities = 159/536 (29%), Positives = 221/536 (41%), Gaps = 92/536 (17%)

Query: 1055 CPASCKSPRPSC-GPLCREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSP 1111
            C  SC +    C    C  GCVC PG L SD    CI    C C +N   Y+PG      
Sbjct: 818  CLRSCHTLDVGCFSTHCVSGCVCPPG-LVSDGSGGCIAEEDCPCVHNEATYKPGET---- 872

Query: 1112 NCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRH 1171
                        RV+C          C  +N ++ C       TC+ YGD H++TFDG  
Sbjct: 873  -----------IRVDCN--------TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 913

Query: 1172 FGFMGKCTYILAQP-CG-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR 1229
            + F G C YILAQ  CG N+T   FR+  +N   G  G +C   + + +    + L +G 
Sbjct: 914  YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGT 973

Query: 1230 RTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCG 1289
               V       P  P K  ++G    F+ ++T  G+ V WD    +++ +   Y G++CG
Sbjct: 974  FKAVARGPGGDP--PYKIRYMGI---FLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCG 1027

Query: 1290 LCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSM 1349
            LCGN+D N+ ND      S  GD  E GNSW+        C        P   +  + S 
Sbjct: 1028 LCGNFDDNAINDFATRSRSVVGDALEFGNSWKL----SPSCPDALAPKDPCTANPFRKSW 1083

Query: 1350 SGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMTTTC 1406
            +    C  L   HGP F  C   V +  ++++C+ D C     G     CT ++     C
Sbjct: 1084 AQKQ-CSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQAC 1139

Query: 1407 QDAGHAVKPWREPHFCPMACP---PNS----KYSLCAKPCPDTCHSGFSGMFCSDRCVEA 1459
             DAG  V  WR P  CP+ C    P+      Y  C  PC  TC +           +E 
Sbjct: 1140 HDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEG 1198

Query: 1460 C--ECNPG---FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRC 1514
            C  +C P    F    ++C+  +QCGC    G+Y+ VG R   P  +    C+S N   C
Sbjct: 1199 CYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNYYDVGAR--VPTAEN---CQSCN---C 1248

Query: 1515 QPWRCRAQEFCGQQDGIYGCHAQGAATCT------ASGDPHYLTFDGALHHFMGTC 1564
             P             GI   H+  A TCT      +  D  Y T DG     +G C
Sbjct: 1249 TP------------SGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDG-----LGAC 1287



 Score =  164 bits (415), Expect = 1e-39
 Identities = 261/1104 (23%), Positives = 397/1104 (35%), Gaps = 126/1104 (11%)

Query: 516  SNTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPS------ETTGLTENPTISTKK 569
            S  +S     +IL    T         P  +P S+ G +       TT  T   T ST  
Sbjct: 4383 STPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTAT 4442

Query: 570  PTVSIEKPSVTTEKPTVPKEKPTIPT-EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTI 628
            P+ +     + TE  T      T+PT    T S+ + T  +   +  +  PT+ S K T 
Sbjct: 4443 PSSTPGTTWILTEPSTTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT- 4499

Query: 629  LTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688
                 + P     +P+ + T +T   T  T  P++    T T + +   PT   S  T  
Sbjct: 4500 ---PSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT-- 4554

Query: 689  PSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT-----PTE 743
               P+  P      T++ T   T +    ++ T   T  T  +T  P   TT     P+ 
Sbjct: 4555 ---PSSTPETVHTSTVL-TATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 4610

Query: 744  KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
             P      P       T  T  PT S   +T P+  P        + T   T++T    T
Sbjct: 4611 SPGTALTPPVWISTTTTPTTTTPTTSGSTVT-PSSIPGTTHTARVLTTTTTTVATGSMAT 4669

Query: 804  PTEETTISTEKPSIPMEKPTLPTEETTT---SVEETTISTEKLTIPMEKPTISTEKPTIP 860
            P+  T  S   PS+     T+    +TT   S   TT  T  LT     P  ++ K T  
Sbjct: 4670 PSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSS 4729

Query: 861  TEKPTISP-EKLTIPTEKLTIPTEKP----------TIPIEETTISTEKLTIPTEKPTIS 909
            +   T +    LT    K T  +  P          T+P + TT  +   TI T     +
Sbjct: 4730 SSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPET 4789

Query: 910  PEKPTISTEKPTIPTEKPTIPTEETTISTEKL------TIPTEKPTISPEKLTIPTEKPT 963
                T+ T   T+     +  T  +T+ T ++      T  T   T S   L+       
Sbjct: 4790 THTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTW 4849

Query: 964  ISTEKPTIPTEKLTIPT-------------EKPTIPTEKPTIPTEKLTALRPPHPSPTAT 1010
            I TE  TI T  + +PT               P + T   T+PT   TA   P  S   T
Sbjct: 4850 ILTEPSTIAT--VMVPTGSTATASSTLGTAHTPKVVTTMATMPTA--TASTVPSSSTVGT 4905

Query: 1011 GLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYES-CACPASC---------- 1059
                 V+    P+  +++V     TT R +     P++ + + C C A            
Sbjct: 4906 TRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGF---PSSHFSTPCFCRAFGQFFSPGEVIY 4962

Query: 1060 -KSPRPSCG--PLCRE---------GCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE 1107
             K+ R  C    +C +          C  +P  + S      + +  C       +    
Sbjct: 4963 NKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNET 5022

Query: 1108 WFSPNCTEHCRCWPGSRVE-------CQISQCGTHTVCQLKNGQYGCH-PYAGTATCLVY 1159
            W   NCT   RC   +RV          ++    H   ++ +    C   Y     C ++
Sbjct: 5023 WTLENCTV-ARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMW 5081

Query: 1160 GDPHYVTFDGRHFGFMGKCTYILAQPC----GNST---DPFFRVTAKNEEQGQEGVSCLS 1212
            G  HY TFDG  + F G CTY+L +      GN +   D  +  TA            LS
Sbjct: 5082 GGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHY-CTASATAAAARCPRALS 5140

Query: 1213 KVYVTLP-ESTVTLLKGRRT-LVGGQQVTLPAIPSK-GVF---LGASGRFVELQTEFGLR 1266
              Y ++    TVT++ G+   L+   Q+ + +  SK GV    LG +   V++    G+ 
Sbjct: 5141 IHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPA-LGVS 5199

Query: 1267 VRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDE 1326
            V ++G         S +     G CG    N  +D L+ DG+ A   +++  +W      
Sbjct: 5200 VTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSR 5259

Query: 1327 DQECQKYQVVNSPSCDSSLQSSMSGPGFC--GRLVD--THGPFETCLLHVKAASFFDSCM 1382
               C         +  ++  SS   P  C    L D      F  C   V    FF++C+
Sbjct: 5260 KDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACI 5319

Query: 1383 LDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWR--EPHFCPMACPPNSKYSLCAKPCP 1440
             D C  +G   + C  +      C+  G     WR      C + CPP   Y  C    P
Sbjct: 5320 SDHC--RGRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQP 5376

Query: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLEC-IPRSQCGCLHPAGSYFKVGERWYKPG 1499
             TC+S        +   E C C    +L      I    C C+ P G     GERW    
Sbjct: 5377 ATCNSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVS-N 5434

Query: 1500 CKELCVC-ESNNRIRCQPWRCRAQ 1522
            C+  CVC E +  ++C+P  C AQ
Sbjct: 5435 CQS-CVCDEGSVSVQCKPLPCDAQ 5457



 Score =  153 bits (387), Expect = 2e-36
 Identities = 116/493 (23%), Positives = 197/493 (39%), Gaps = 57/493 (11%)

Query: 1044 CPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFL------FSDNHCIQASSC 1093
            CP N +++ C  P +  C +P+ +  C   C +GC C PG         + + C+    C
Sbjct: 329  CPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQC 388

Query: 1094 NCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGT 1153
             C +    Y PG   F+  C+                       C    G + C      
Sbjct: 389  PCTHGGRTYSPGTS-FNTTCSS----------------------CTCSGGLWQCQDLPCP 425

Query: 1154 ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLS 1212
             TC V G  H  T+D + +   G C+Y+L++ C +S+   F V A+  + G  +  +CL 
Sbjct: 426  GTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSS---FTVLAELRKCGLTDNENCLK 482

Query: 1213 KVYVTLP--ESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLR--VR 1268
             V ++L   ++ + +       +      LP   +       S  F+ +QT  GL+  V+
Sbjct: 483  AVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQ 542

Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
                 Q++V +   + G++CGLCGN++ N  +D   L G          N+W+       
Sbjct: 543  LVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKA----QA 598

Query: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388
             C   +      C  S+++      +C RL D +  F  C   +    F  +CM D C  
Sbjct: 599  ACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNC 658

Query: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP---MACPPNSKYSLCAKPCPDTCHS 1445
            +  +  LC  +S+    C   G  +  WR+   C      CP + +Y+     C  TC  
Sbjct: 659  ERSEDCLCAALSSYVHACAAKGVQLSDWRD-GVCTKYMQNCPKSQRYAYVVDACQPTCRG 717

Query: 1446 -GFSGMFCSDRC--VEACECNPG-FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501
               + + CS     V+ C C  G F+     C+P  +C C +  G+    GE  +  G  
Sbjct: 718  LSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC-YAHGTVLAPGEVVHDEGA- 775

Query: 1502 ELCVCESNNRIRC 1514
             +C C +  ++ C
Sbjct: 776  -VCSC-TGGKLSC 786



 Score =  151 bits (382), Expect = 7e-36
 Identities = 135/524 (25%), Positives = 205/524 (39%), Gaps = 97/524 (18%)

Query: 1844 CAESCECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNIT 1902
            C   C C  G +  G+  C+    C C     +Y P GE   T       CTC  +    
Sbjct: 834  CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKP-GE---TIRVDCNTCTCR-NRRWE 888

Query: 1903 CFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVK-VC 1961
            C    C                   +G C   G+ H+++FDG  +S   +C  +L +  C
Sbjct: 889  CSHRLC-------------------LGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 929

Query: 1962 HPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAI 2020
                    F+I  ++      GT   +  +++++ Y+  + LQ+G          T  A+
Sbjct: 930  GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYE--LILQEG----------TFKAV 977

Query: 2021 SQIPG----VSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEE 2076
            ++ PG      ++   I+ ++    G+ V +D    + I +   Y G+VCG+CGNF+D  
Sbjct: 978  ARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNA 1036

Query: 2077 EDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR 2136
             ++    S  V     EF NSWK   + PSC   L             P   C A   R+
Sbjct: 1037 INDFATRSRSVVGDALEFGNSWK---LSPSCPDALA------------PKDPCTANPFRK 1081

Query: 2137 --AREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQALCQALQAFGATCQ 2192
              A+++C + L  P +A C S++D T +   C N    C+ GG  +  C A+ A+   C 
Sbjct: 1082 SWAQKQC-SILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACH 1140

Query: 2193 SQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSCWDLDGRCEGAKVPSACA 2245
              GL    WR    CPL C  Y+        Y  C   C  +C +  G C    V     
Sbjct: 1141 DAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHC---LVDLPGL 1196

Query: 2246 EGCI-----CQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQ 2300
            EGC       QP +   + KCV  +QCGC D  G    +G    ++   + C CT   IQ
Sbjct: 1197 EGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQ 1254

Query: 2301 CGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
            C                +S   C     ++   Y D  Y T DG
Sbjct: 1255 CA---------------HSLEACTCTYEDRTYSYQDVIYNTTDG 1283



 Score =  139 bits (350), Expect = 4e-32
 Identities = 128/480 (26%), Positives = 185/480 (38%), Gaps = 60/480 (12%)

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
            DR   AC  +P  V S     P    GC + A    +V E W    C  +  C  +NR+ 
Sbjct: 4983 DRFQGACPTSPPPVSSAPLSSPSPAPGCDN-AIPLRQVNETWTLENCT-VARCVGDNRVV 5040

Query: 1514 CQPWRCRAQEFCGQQ-------DGIYGC--HAQGAATCTASGDPHYLTFDGALHHFMGTC 1564
                +  A   C  +       D    C  H +    C+  G  HY TFDG  + F G C
Sbjct: 5041 LLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNC 5100

Query: 1565 TYVLTRPCWSR-------SQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGC 1617
            TYVL R   +R         + Y   SAT              ++H    D+ +++    
Sbjct: 5101 TYVLMREIHARFGNLSLYLDNHYCTASAT----AAAARCPRALSIHYKSMDIVLTV---- 5152

Query: 1618 KVMLNGHRVALPVWLAQGRVTIRLSSNLVLL-----------YTNFGLQVRYDGSHLVEV 1666
              M++G    L +   Q  V+   S N VL+               G+ V ++G      
Sbjct: 5153 -TMVHGKEEGL-ILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQAR 5210

Query: 1667 TVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP 1726
               S +     G CG   NN  DD L+ D   A     +   W +P+S + GC+   G P
Sbjct: 5211 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTP 5270

Query: 1727 SSCQENSMADAW--------NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGD 1778
             +    +   +            C ++++    F++CH +VPP   F +C+   C  +G 
Sbjct: 5271 PTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--VFAECHNLVPPGPFFNACISDHC--RGR 5326

Query: 1779 TTALCRSLQAYASLCAQAGQAPAWRNRT--FCPMRCPPGSSYSPCSSPCPDTCSSINNPR 1836
                C+SL+AYA LC   G    WR  T   C + CPP   Y PC    P TC+S N   
Sbjct: 5327 LEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRN--- 5383

Query: 1837 DCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTC 1895
              P+    AE C C +  IL      + +  C C  P G     GERW +     + C C
Sbjct: 5384 QSPQLEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSN---CQSCVC 5440



 Score =  100 bits (249), Expect = 2e-20
 Identities = 151/568 (26%), Positives = 208/568 (36%), Gaps = 51/568 (8%)

Query: 530  NPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKE 589
            N G CP    P     +  SST P  T  LTE  T +T   T        +T     P +
Sbjct: 2970 NYGHCPST--PATSSTATPSST-PGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPK 3026

Query: 590  KPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS--EKPTILTEKPTIPS----EKPTIP 643
              T     PT ++ K T  S  P   +  P + S   K T  +  P IPS       T+P
Sbjct: 3027 VLTSTATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSFTP-IPSFTLGTTGTLP 3084

Query: 644  SEKPTISTEKPTV-PTEEP-TTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME 701
             +  T      T+ P+  P TT T    T+       T   S P+  P        ++  
Sbjct: 3085 EQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTA 3144

Query: 702  ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKP-TISPEKPT 760
             T  +   PT +P      T   T P+  +T++    +T T   T  T     +     T
Sbjct: 3145 ATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTAT 3204

Query: 761  TPT-----EKPTISPEKLT-IPTEKPTIPTEKPTIPTEKPTIS-----TEEPTTPTEETT 809
            TPT       P+ SP   T +P  + T  T   T  T  P+ S     T    T T   T
Sbjct: 3205 TPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTAT 3264

Query: 810  ISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP--TISTEKPTIPTEKPTIS 867
            +ST  PS   E  T+ T    T+   TT +T  +  P   P    +T+ PT  T   T +
Sbjct: 3265 MSTATPSSTPE--TVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 3322

Query: 868  PEKLTIPTEKLTIPTEKPTIPIEETTISTEK--LTIPTEKPTISPEKPTISTEKPTIPTE 925
            P   + P   LT     P + I  TT  T +     P+  P  +     ++T   T+ T 
Sbjct: 3323 PS--SSPGTALT-----PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 3375

Query: 926  KPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985
                P+  T  S    ++ T   TI+    T        +T  P + T   T P      
Sbjct: 3376 SMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA----- 3430

Query: 986  PTEKPTIPTEKL-TALRPPHPSPTAT--GLAALVMSPHAPSTPMTSV---ILGTT--TTS 1037
             T     P+  L T   PP P+ TAT  G +    SPH   T  TS    ILGTT  T  
Sbjct: 3431 ATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 3490

Query: 1038 RSSTERCPPNARYESCACPASCKSPRPS 1065
             + T   P      +     +  SP PS
Sbjct: 3491 STVTSHTPAATTSTTQHSTPALSSPHPS 3518



 Score = 99.4 bits (246), Expect = 4e-20
 Identities = 152/613 (24%), Positives = 222/613 (36%), Gaps = 62/613 (10%)

Query: 468  LLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFI 527
            +L SPA +P     K   S  P    T+ T+P        L     + + T+        
Sbjct: 4284 VLTSPATTPTATSSKATSSSSP---RTATTLPV-------LTSTATKSTATSVTPIPSST 4333

Query: 528  LINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVP 587
            L   GT P +      PV+ +S+  PS T   T   T+ T K T +  + + +T  P+  
Sbjct: 4334 LGTTGTLPEQTTT---PVATMSTIHPSSTPETTHTSTVLTTKATTT--RATSSTSTPSST 4388

Query: 588  KEKPTIPTEKPT-ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTE-----KPTIPSEKP- 640
                 I TE  T  +T   T P+  P+       I +E  T  T          PS  P 
Sbjct: 4389 PGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPG 4448

Query: 641  -----TIPSEKPTIST---EKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIP 692
                 T PS   T++       T  + + T  T   +T+   P + + K + P+  P   
Sbjct: 4449 TTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSK-ATPSSSPGTA 4507

Query: 693  TEKPTISMEETIISTEKPTISPEKPTIPT----EKPTIPT-EKSTISPEKPTTPTEKPTI 747
            T  P +    T  +    T  P      T     + T PT   ST +P          T+
Sbjct: 4508 TALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTV 4567

Query: 748  PTEKPTISPEKPTTPTEKPTISPEKLT-IPTEKPT----IPTEKPTIPTEKPT--ISTEE 800
             T   T +    +  T   T      T +PT   T     P+  P      P    +T  
Sbjct: 4568 LTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTT 4627

Query: 801  PTTPTEETTISTEKP-SIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859
            PTT T  T+ ST  P SIP    T     TTT    TT++T  +  P      S   P++
Sbjct: 4628 PTTTTPTTSGSTVTPSSIPGTTHTARVLTTTT----TTVATGSMATPSSSTQTSGTPPSL 4683

Query: 860  PTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPT---IS 916
             T   TI+    T  T   + P   P  P+  +T +T   T      + SP   T   + 
Sbjct: 4684 TTTATTITATGST--TNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVL 4741

Query: 917  TEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKL 976
            T   T  T     P   +T+ T   T+P +  T      TI T     +T   T+ T   
Sbjct: 4742 TSTATKSTATSFTPIPSSTLWT-TWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTA 4800

Query: 977  TIPTEKPTIPTEKPTIPTEK-LTALRPPHPSPTATGLAALVMSPHA-------PSTPMTS 1028
            T+     +  T   T+ T + LT L     +  ATG  A + S          PST  T 
Sbjct: 4801 TMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATV 4860

Query: 1029 VILGTTTTSRSST 1041
            ++   +T + SST
Sbjct: 4861 MVPTGSTATASST 4873



 Score = 95.1 bits (235), Expect = 8e-19
 Identities = 149/593 (25%), Positives = 225/593 (37%), Gaps = 79/593 (13%)

Query: 468  LLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFI 527
            +L S A +P     K   S  P    T+ T+P        L     + + T+      F 
Sbjct: 3027 VLTSTATTPTATSSKATSSSSP---RTATTLPV-------LTSTATKSTATSFTPIPSFT 3076

Query: 528  LINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVP 587
            L   GT P +      P++ +S+  PS T   T   T+ T K T +    S++T  P+  
Sbjct: 3077 LGTTGTLPEQTTT---PMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMST--PSST 3131

Query: 588  KEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPS-EK 646
                 I TE  T +T      +     P+  P+       ILTE  T  +   T+P+   
Sbjct: 3132 PGTTWILTELTTAAT------TTAATGPTATPSSTPGTTWILTEPSTTATV--TVPTGST 3183

Query: 647  PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEK--PTISMEETI 704
             T S+ + T  T +  T T  T T +     P+  P   T  P++ +    PT +    I
Sbjct: 3184 ATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAI 3243

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTE 764
             S+   T         T   T+ T   + +PE   T T   T  T   T +     TP+ 
Sbjct: 3244 PSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTT--TRATGSVATPSS 3301

Query: 765  KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP----TTPTEETTISTEKPS-IPM 819
             P  +     +PT   T  T     P+  P  +   P    TT T  T  ST  PS IP 
Sbjct: 3302 TPGTA-HTTKVPT---TTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG 3357

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEK-------PTISTEKPTIPTEKPTISPEKLT 872
               T     TTT    TT++T  +  P          P+++T   TI     T +P    
Sbjct: 3358 TTHTATVLTTTT----TTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS--- 3410

Query: 873  IPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP------TISPEKP--TISTEKPTIPT 924
                  + P   P  P+  TT +T   T  T  P      T +P  P  T +T   ++P 
Sbjct: 3411 ------STPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPP 3464

Query: 925  EKP-TIPTEETT-----ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTI 978
              P T+ T  T+     + T  +T P+   + +P   T  T+  T +   P  P+ + T 
Sbjct: 3465 SSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPH-PSSRTTE 3523

Query: 979  PTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAP-STPMTSVI 1030
                P   T   T  T + TA   P  + T+T      + P +P S P+T+V+
Sbjct: 3524 SPPSPGTTTPGHTRGTSRTTATATPSKTRTST------LLPSSPTSAPITTVV 3570



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 153/568 (26%), Positives = 209/568 (36%), Gaps = 73/568 (12%)

Query: 530  NPGTCPVKVLPELPPVSPVSSTGPSETTGLTE-NPTISTKKPTVSIEKPSVTTEKPTVPK 588
            N G CP    P     +  SST P  T  LTE   T +T   T S   PS T      PK
Sbjct: 4227 NYGHCPST--PATSSTAMPSST-PGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPK 4283

Query: 589  EKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS--EKPTILTEKPTIPSE----KPTI 642
               T P   PT ++ K T  S  P   +  P + S   K T  +  P IPS       T+
Sbjct: 4284 VL-TSPATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSVTP-IPSSTLGTTGTL 4340

Query: 643  PSEKPT-ISTEKPTVPTEEP-TTPTEETTTSMEEPVIPTEKPSIPTEKPS---IPTEKPT 697
            P +  T ++T     P+  P TT T    T+       T   S P+  P    I TE  T
Sbjct: 4341 PEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTT 4400

Query: 698  ISMEETIIS-TEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP----------- 745
             +        T  P+ +P    I TE  T  T  +T S     TP+  P           
Sbjct: 4401 AATTTAATGPTATPSSTPGTTWILTELTT--TATTTASTGSTATPSSTPGTTWILTEPST 4458

Query: 746  ----TIPT--------EKPTISPEKPTTPTEKPTISPEKLTIPTEKP----TIPTEKPTI 789
                T+PT         + T      +T    PT++  K T P+  P     +P  + T 
Sbjct: 4459 TATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-PSSSPGTATALPALRSTA 4517

Query: 790  PTEKPTISTEEPT------------TPTEETTISTEKPSIPMEKPTLPTEETTTSVEETT 837
             T   T  T  P+            T T   T+ST  PS   E  T+ T    T+   TT
Sbjct: 4518 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE--TVHTSTVLTATATTT 4575

Query: 838  ISTEKLTIPMEKP--TISTEKPTIPTEKPTISPEKLTIPTEKLTIPT--EKPTIPIEETT 893
             +T  +  P   P    +T+ PT  T   T +P   + P   LT P      T P   T 
Sbjct: 4576 GATGSVATPSSTPGTAHTTKVPTTTTTGFTATPS--SSPGTALTPPVWISTTTTPTTTTP 4633

Query: 894  ISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
             ++     P+  P  +     ++T   T+ T     P+  T  S    ++ T   TI+  
Sbjct: 4634 TTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTIT-- 4691

Query: 954  KLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA 1013
              T  T  P+ ST   T  T  LT     P   + K T  +   TA   P  + TAT   
Sbjct: 4692 -ATGSTTNPS-STPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKST 4749

Query: 1014 ALVMSPHAPSTPMTSVILGTTTTSRSST 1041
            A   +P   ST  T+  +   TT+  ST
Sbjct: 4750 ATSFTPIPSSTLWTTWTVPAQTTTPMST 4777



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 121/519 (23%), Positives = 191/519 (36%), Gaps = 77/519 (14%)

Query: 1825 CPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWY 1884
            C   C        CP + P   S        LS  S  P    GC D A     V E W 
Sbjct: 4976 CNQHCDIDRFQGACPTSPPPVSSAP------LSSPSPAP----GC-DNAIPLRQVNETWT 5024

Query: 1885 TENTCTRLCTCSVHN-----------NITCFQS-----TCKPNQICWALDGLLRCRASGV 1928
             EN CT +  C   N           N+TC           P+Q C   D    C     
Sbjct: 5025 LEN-CT-VARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPC---DFHYECEC--- 5076

Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPA---MALPFFKISAKHEKEEGGTEA 1985
             +C + G SHY +FDG++++    CT VL++  H     ++L                  
Sbjct: 5077 -ICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARC 5135

Query: 1986 FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPG----------VSVKSSSIYS 2035
             R   ++    D  +T+      +++ K+  L    QIP           VSV  ++   
Sbjct: 5136 PRALSIHYKSMDIVLTV-----TMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMR 5190

Query: 2036 IVNIKIGVQVKFDGNHLLEIEIP-TTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEF 2094
            +    +GV V F+G  + +  +P + ++    G CG   + + D+ +      A S  + 
Sbjct: 5191 VDIPALGVSVTFNG-QVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDM 5249

Query: 2095 VNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCA 2154
              +W     D             P      P  +         +  C+  L + V+A+C 
Sbjct: 5250 AKTWLVP--DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLML-SQVFAECH 5306

Query: 2155 SRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSS--FCPLECP 2212
            + +   PF   C +  C   G  +  CQ+L+A+   C+++G+    WR ++   C L CP
Sbjct: 5307 NLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARGVCSD-WRGATGGLCDLTCP 5363

Query: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDK---CVPRSQCGC 2269
                Y  C P    +C   + R +  ++    AEGC C    +L       CV    C C
Sbjct: 5364 PTKVYKPCGPIQPATC---NSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICV--QACPC 5417

Query: 2270 KDAHGGSIPLGKSWVSSGCTEKCVCTGG--AIQCGDFRC 2306
                G     G+ WVS+   + CVC  G  ++QC    C
Sbjct: 5418 VGPDGFPKFPGERWVSN--CQSCVCDEGSVSVQCKPLPC 5454



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 129/494 (26%), Positives = 195/494 (39%), Gaps = 89/494 (18%)

Query: 554  SETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT-EKPTISTEKPTIPSEKP 612
            +E+TG T  P+ ST   T  + +PS T    TV     T+PT    T S+ + T  +   
Sbjct: 3706 TESTGSTATPS-STPGTTWILTEPSTTA---TV-----TVPTGSTATASSTQATAGTPHV 3756

Query: 613  NMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSM 672
            +  +  PT+ S K T  +     P     +P+ + T +T   T  T  P++    T T +
Sbjct: 3757 STTATTPTVTSSKATPFSS----PGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRL 3812

Query: 673  EEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKST 732
             +   PT   S  T     P+  P  +   T+++T                    T  +T
Sbjct: 3813 SQTTTPTATMSTAT-----PSSTPETAHTSTVLTT--------------------TATTT 3847

Query: 733  ISPEKPTTPTEKP-TIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
             +     TP+  P T  T K       PTT T   T++P             +   T  T
Sbjct: 3848 RATGSVATPSSTPGTAHTTKV------PTTTTTGFTVTPS------------SSPGTART 3889

Query: 792  EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
                IST   TTPT  T+ ST  PS        PT  TTT+   TT++T  +  P     
Sbjct: 3890 PPVWIST--TTTPT--TSGSTVTPSSVPGTTHTPTVLTTTT---TTVATGSMATPSSSTQ 3942

Query: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP----- 906
             S   P++ T   TI+    T  T   + P   P  P+  TT +T   T  T  P     
Sbjct: 3943 TSGTPPSLITTATTITATGST--TNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALG 4000

Query: 907  -TISPEKP--TISTEKPTI-PTEKPTIPTEET-----TISTEKLTIPTEKPTISPEKLTI 957
             T +P  P  T +T   ++ P+   T+ T  T     T+ T  +T P+   + +P   T 
Sbjct: 4001 TTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTG 4060

Query: 958  PTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVM 1017
             T+  T +   P  P+ + T     P   T   T  T + TA   P  + T+T      +
Sbjct: 4061 TTQHSTPALSSPH-PSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTST------L 4113

Query: 1018 SPHAP-STPMTSVI 1030
             P +P S P+T+V+
Sbjct: 4114 LPSSPTSAPITTVV 4127



 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 143/519 (27%), Positives = 201/519 (38%), Gaps = 79/519 (15%)

Query: 530  NPGTCPVKVLPELPPVSPVSSTGPSETTGLTE-NPTISTKKPTVSIEKPSVTTEKPTVPK 588
            N G CP    P     +  SST P  T  LTE   T +T + T S   PS T     +  
Sbjct: 2413 NYGHCPST--PATSSTAMPSST-PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILT 2469

Query: 589  EKPTIPTEK-PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            E  T  T   PT ST   +        P    T  +         PT+ S K T P   P
Sbjct: 2470 EPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT---------PTVTSSKAT-PFSSP 2519

Query: 648  TISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIST 707
              +T  P + +   TTPT  + T++    + T    +        T  PT +M     ST
Sbjct: 2520 GTATALPALRSTA-TTPTATSFTAIPSSSLGTTWTRLSQ------TTTPTATM-----ST 2567

Query: 708  EKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP-TIPTEKPTISPEKPTTPTEKP 766
              P+ +PE  T+ T      T  +T +     TP+  P T  T K        TT T   
Sbjct: 2568 ATPSSTPE--TVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVL------TTTTTGF 2619

Query: 767  TISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPT 826
            T +P          + P    T+P     IST   TTPT  T  ST  PS        PT
Sbjct: 2620 TATPS---------SSPGTARTLPV---WISTT--TTPT--TRGSTVTPSSIPGTTHTPT 2663

Query: 827  EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT 886
              TTT+   TT++T  +  P      S   P++ T   TI+    T  T   + P   P 
Sbjct: 2664 VLTTTT---TTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST--TNPSSTPGTTPI 2718

Query: 887  IPIEETTISTEKLTIPTEKP------TISPEKP--TISTEKPTI-PTEKPTIPTEET--- 934
             P+  TT +T   T  T  P      T +P  P  T +T   ++ P+   T+ T  T   
Sbjct: 2719 PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSAT 2778

Query: 935  --TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTI 992
              T+ T  +T P+   + +P   T  T+  T +   P  P+ + T     P   T   T 
Sbjct: 2779 SGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPH-PSSRTTESPPSPGTTTPGHTR 2837

Query: 993  PTEKLTALRPPHPSPTATGLAALVMSPHAP-STPMTSVI 1030
             T + TA   P  + T+T      + P +P S P+T+V+
Sbjct: 2838 ATSRTTATATPSKTRTST------LLPSSPTSAPITTVV 2870



 Score = 80.1 bits (196), Expect = 3e-14
 Identities = 112/471 (23%), Positives = 172/471 (36%), Gaps = 62/471 (13%)

Query: 571  TVSIEKPSVTTEKPTV-PKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL 629
            T S   PS T     +  K   T  T   T ST  PT  + +   P +  T  +  PT+ 
Sbjct: 1894 TSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPT-STLRTAPPPKVLTTTATTPTVT 1952

Query: 630  TEKPTIPSEKP----TIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
            + K T PS  P     +P+ + T +T   T  T  P++    T T + +   PT   S  
Sbjct: 1953 SSKAT-PSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTA 2011

Query: 686  TEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT----- 740
            T     P+  P  +   T++ T   T +    ++ T   T  T  +T  P   TT     
Sbjct: 2012 T-----PSSTPETAHTSTVL-TATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 2065

Query: 741  PTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
            P+  P      P       T  T   T++P  +   T   T+ T   T      T++T  
Sbjct: 2066 PSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT------TVATGS 2119

Query: 801  PTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP 860
              TP+  T  S   PS+     T+    +TT+   T  +T    IP   P ++T   T  
Sbjct: 2120 MATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTT---PIP---PVLTTTATTPA 2173

Query: 861  TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920
                T++P      T          T P+  T  +T   ++P      SP     +    
Sbjct: 2174 ATSNTVTPSSALGTTH---------TPPVPNTMATTHGRSLPPS----SPHTVRTAWTSA 2220

Query: 921  TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPT 980
            T      T  TE +T+++  L   T     S   L+ P             P+ + T   
Sbjct: 2221 TSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPH------------PSSRTTESP 2268

Query: 981  EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAP-STPMTSVI 1030
              P   T   T  T + TA   P  + T+T      + P +P S P+T+V+
Sbjct: 2269 PSPGTTTPGHTTATSRTTATATPSKTRTST------LLPSSPTSAPITTVV 2313



 Score = 80.1 bits (196), Expect = 3e-14
 Identities = 118/468 (25%), Positives = 174/468 (37%), Gaps = 87/468 (18%)

Query: 661  PTTPTEETTTSMEEPVIPTEKPS---IPTEKPSIPTEKPTISMEETIISTEKPTISPEKP 717
            P+TP   +T       +P+  P    I TE  +  T   +     T  ST      P+  
Sbjct: 4232 PSTPATSSTA------MPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVL 4285

Query: 718  TIPTEKPTIPTEKSTISPEKPTTPTEKPTI-------------PTEKPTIS-----PEKP 759
            T P   PT  + K+T S   P T T  P +             P    T+      PE+ 
Sbjct: 4286 TSPATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQT 4344

Query: 760  TTP-TEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTE-KPSI 817
            TTP     TI P      T   T+ T K T  T + T ST  P++    T I TE   + 
Sbjct: 4345 TTPVATMSTIHPSSTPETTHTSTVLTTKAT--TTRATSSTSTPSSTPGTTWILTELTTAA 4402

Query: 818  PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTE- 876
                 T PT   +++   T I TE  T      T +T   T  T  P+ +P    I TE 
Sbjct: 4403 TTTAATGPTATPSSTPGTTWILTELTT------TATTTASTGSTATPSSTPGTTWILTEP 4456

Query: 877  ----KLTIPT-EKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPT---IPTEKPT 928
                 +T+PT    T    + T  T  ++     PT++  K T S+   T   +P  + T
Sbjct: 4457 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRST 4516

Query: 929  IPTEETT-------------------ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
              T   T                    +T   T+ T  P+ +PE  T+ T     +T   
Sbjct: 4517 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE--TVHTSTVLTATATT 4574

Query: 970  TIPTEKLTIPTEKP--TIPTEKPTIPTEKL---------TALRPP-------HPSPTATG 1011
            T  T  +  P+  P     T+ PT  T            TAL PP        P+ T   
Sbjct: 4575 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPT 4634

Query: 1012 LAALVMSPHA-PSTPMTSVILGTTTTSRSSTERCPPNARYESCACPAS 1058
             +   ++P + P T  T+ +L TTTT+ ++     P++  ++   P S
Sbjct: 4635 TSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPS 4682



 Score = 78.6 bits (192), Expect = 8e-14
 Identities = 120/478 (25%), Positives = 177/478 (37%), Gaps = 60/478 (12%)

Query: 612  PNMPSEKPTI-PSEKPT---ILTEKPTIPSEKPT-----IPSEKPTISTEKPTVPTEEPT 662
            P+ P+   T  PS  P    ILTE+ T  +   T     IPS  P  +   P V T   T
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPG-TAPPPKVLTSTAT 3033

Query: 663  TPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS-PEKPTIPT 721
            TPT  ++ +           S P    ++P    T +       T  P+ +     T+P 
Sbjct: 3034 TPTATSSKATSS--------SSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPE 3085

Query: 722  EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPT 781
            +  T     STI P      T   T+ T K T +  + T+    P+ +P    I TE  T
Sbjct: 3086 QTTTPMATMSTIHPSSTPETTHTSTVLTTKATTT--RATSSMSTPSSTPGTTWILTELTT 3143

Query: 782  IPTEKP-TIPTEKPTIST------EEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVE 834
              T    T PT  P+ +        EP+T    T  +    +    + T  T +  TS  
Sbjct: 3144 AATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTA 3203

Query: 835  ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT-IPTEKLTIPTEKPTIPIEETT 893
             T         P   P  +T  P + +   T +   +T IP+  L     +    + +TT
Sbjct: 3204 TTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTR----LSQTT 3259

Query: 894  ISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
              T   T+ T  P+ +PE         T+ T      T  TT +T  +  P+  P  +  
Sbjct: 3260 TPTA--TMSTATPSSTPE---------TVHTSTVLTTTTTTTRATGSVATPSSTPG-TAH 3307

Query: 954  KLTIPTEKPTISTEKP-TIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGL 1012
               +PT   T  T  P + P   LT P    T  T  PT     +T    P  + TAT L
Sbjct: 3308 TTKVPTTTTTGFTATPSSSPGTALTPPVWIST--TTTPTTRGSTVTPSSIPGTTHTATVL 3365

Query: 1013 AALVMSPHAPSTPMTSVILGTTTTSRSSTER--CPPNARYESCACPASCKSPRPSCGP 1068
                      +T  T+V  G+  T  SST+    PP+    +    A+  +  PS  P
Sbjct: 3366 ----------TTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTP 3413



 Score = 78.2 bits (191), Expect = 1e-13
 Identities = 102/368 (27%), Positives = 141/368 (38%), Gaps = 36/368 (9%)

Query: 689  PSIPTEKPTISMEET-----IISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTE 743
            PS P    T +   T     I++    T +    T  T  PT  T ++   P+  TT   
Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPT-STLRTAPPPKVLTTTAT 1947

Query: 744  KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
             PT+ + K T S   P T T  P +     T PT     P    ++ T    +S  + TT
Sbjct: 1948 TPTVTSSKATPS-SSPGTATALPALR-STATTPTATSVTPIPSSSLGTTWTRLS--QTTT 2003

Query: 804  PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP--TISTEKPTIPT 861
            PT   T+ST  PS   E  T  T    T+   TT +T  +  P   P    +T+ PT  T
Sbjct: 2004 PT--ATMSTATPSSTPE--TAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTT 2059

Query: 862  EKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEK--LTIPTEKPTISPEKPTISTEK 919
               T +P   + P   LT     P + I  TT  T +     P+  P  +     ++T  
Sbjct: 2060 TGFTATPS--SSPGTALT-----PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 2112

Query: 920  PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979
             T+ T     P+  T  S    ++ T   TI+    T        +T  P + T   T P
Sbjct: 2113 TTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTP 2172

Query: 980  TEKPTIPTEKPTIPTEKL-TALRPPHPSPTAT--GLAALVMSPHAPSTPMTSV---ILGT 1033
                   T     P+  L T   PP P+  AT  G +    SPH   T  TS    ILGT
Sbjct: 2173 A-----ATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGT 2227

Query: 1034 TTTSRSST 1041
            T  +  ST
Sbjct: 2228 THITEPST 2235



 Score = 78.2 bits (191), Expect = 1e-13
 Identities = 115/430 (26%), Positives = 161/430 (37%), Gaps = 54/430 (12%)

Query: 661  PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
            P+TP   +T +      P+  P        + T   T +  E+  ST  P+ +P    I 
Sbjct: 3675 PSTPATSSTAT------PSSTPGTTWILTKLTT---TATTTESTGSTATPSSTPGTTWIL 3725

Query: 721  TEKPT-----IPT-EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774
            TE  T     +PT   +T S  + T  T   +     PT++  K T     P  SP   T
Sbjct: 3726 TEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-----PFSSPGTAT 3780

Query: 775  -IPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSV 833
             +P  + T  T   T  T  P+ S     T   +TT  T   S      T  T  T+T V
Sbjct: 3781 ALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTST-V 3839

Query: 834  EETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETT 893
              TT +T + T  +  P+ ST      T+ PT +    T+           P + I  TT
Sbjct: 3840 LTTTATTTRATGSVATPS-STPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTT 3898

Query: 894  ISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
              T      T   T++P     +T  PT+ T      T  TT++T  +  P+     S  
Sbjct: 3899 TPT------TSGSTVTPSSVPGTTHTPTVLT------TTTTTVATGSMATPSSSTQTSGT 3946

Query: 954  KLTIPTEKPTI----STEKPTIPTEKLTIP---TEKPTIP--TEKPTIPTEKL-TALRPP 1003
              ++ T   TI    ST  P+       IP   T   T P  T     P+  L T   PP
Sbjct: 3947 PPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 4006

Query: 1004 HPSPTATGLAALVMSPHAPS------TPMTSVILGTT--TTSRSSTERCPPNARYESCAC 1055
             P+ TAT      +SP +P       T  TS  LGTT  T   + T   P      +   
Sbjct: 4007 VPNTTAT-THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHS 4065

Query: 1056 PASCKSPRPS 1065
              +  SP PS
Sbjct: 4066 TPALSSPHPS 4075



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 115/437 (26%), Positives = 163/437 (37%), Gaps = 68/437 (15%)

Query: 661  PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
            P+TP   +T       +P+  P        + T   T +  E+  ST  P+ +P    I 
Sbjct: 2418 PSTPATSSTA------MPSSTPGTTWILTELTT---TATTTESTGSTATPSSTPGTTWIL 2468

Query: 721  TEKPT-----IPT-EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774
            TE  T     +PT   +T S  + T  T   +     PT++  K T     P  SP   T
Sbjct: 2469 TEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-----PFSSPGTAT 2523

Query: 775  -IPTEKPTIPTEKPTIPTEKPTIST-------EEPTTPTEETTISTEKPSIPMEKPTLPT 826
             +P  + T  T   T  T  P+ S         + TTPT   T+ST  PS   E  T+ T
Sbjct: 2524 ALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPT--ATMSTATPSSTPE--TVHT 2579

Query: 827  EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT 886
                T+   TT +T  +  P   P  +     + T     +    + P    T+P     
Sbjct: 2580 STVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLP----- 2634

Query: 887  IPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTE 946
            + I  TT  T      T   T++P     +T  PT+ T      T  TT++T  +  P+ 
Sbjct: 2635 VWISTTTTPT------TRGSTVTPSSIPGTTHTPTVLT------TTTTTVATGSMATPSS 2682

Query: 947  KPTISPEKLTIPTEKPTI----STEKPTIPTEKLTIP---TEKPTIP--TEKPTIPTEKL 997
                S    ++ T   TI    ST  P+       IP   T   T P  T     P+  L
Sbjct: 2683 STQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSAL 2742

Query: 998  -TALRPPHPSPTATGLAALVMSPHAPS------TPMTSVILGTT--TTSRSSTERCPPNA 1048
             T   PP P+ TAT      +SP +P       T  TS  LGTT  T   + T   P   
Sbjct: 2743 GTTHTPPVPNTTAT-THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT 2801

Query: 1049 RYESCACPASCKSPRPS 1065
               +     +  SP PS
Sbjct: 2802 TGTTQHSTPALSSPHPS 2818



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 133/547 (24%), Positives = 200/547 (36%), Gaps = 48/547 (8%)

Query: 531  PGTCPVKVLPELPP----VSPVSSTGPSET--TGLTENPTISTKKPTVSIEKPSVTTEKP 584
            PGT     +P        V+P SS G + T    ++   T +T   TV+      TT  P
Sbjct: 3860 PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTP 3919

Query: 585  TVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL-TEKPTIPSEKP-TI 642
            TV      + T   T++T     PS         P++ +   TI  T   T PS  P T 
Sbjct: 3920 TV------LTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTT 3973

Query: 643  PSEKPTISTEKPTVP--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISM 700
            P   P + T   T P  T    TP+    T+   PV  T   +  T   S+    P  ++
Sbjct: 3974 PI--PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNT---TATTHGRSLSPSSPH-TV 4027

Query: 701  EETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKP- 759
                 S    T+     T P+   T  T  +T    + +TP      P+ + T SP  P 
Sbjct: 4028 RTAWTSATSGTLGTTHITEPS-TGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPG 4086

Query: 760  -TTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTE--KPS 816
             TTP      S    T    K    T  P+ PT  P   T   TT  E     +E    S
Sbjct: 4087 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPI--TTVVTTGCEPQCAWSEWLDYS 4144

Query: 817  IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPT----EKPTISPEKLT 872
             PM  P+    +T +++     +  +  + +E    +  +P +P     +    S +   
Sbjct: 4145 YPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLE--CRAQAQPGVPLGELGQVVECSLDFGL 4202

Query: 873  IPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTE 932
            +   +  +   K     E           P+   T S   P+ +     I TE  T  T 
Sbjct: 4203 VCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTT--TA 4260

Query: 933  ETTISTEKLTIPTEKPTIS--PEKLTIPTEKPTISTEKPT---IPTEKLTIP----TEKP 983
             TT ST     P+  P  +  P+ LT P   PT ++ K T    P    T+P    T   
Sbjct: 4261 TTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATK 4320

Query: 984  TIPTEKPTIPTEKL-TALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGT-TTTSRSST 1041
            +  T    IP+  L T    P  + T     + +     P T  TS +L T  TT+R+++
Sbjct: 4321 STATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATS 4380

Query: 1042 ERCPPNA 1048
                P++
Sbjct: 4381 STSTPSS 4387



 Score = 72.4 bits (176), Expect = 6e-12
 Identities = 119/490 (24%), Positives = 175/490 (35%), Gaps = 53/490 (10%)

Query: 580  TTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEK 639
            TT  PT   E  T  T +   ST +PT     P +    P   +  PT L+E  T P   
Sbjct: 1611 TTPPPTTELETATTTTTQALFSTPQPT---SSPGLTRAPPASTTAVPT-LSEGLTSPRYT 1666

Query: 640  PTIPSEKPTISTEKPTVP--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697
             T+     T +T  PT P  + EPT P   T+T      +P    S+ T +PS P   PT
Sbjct: 1667 STL----GTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQP---PT 1719

Query: 698  ISMEETIISTEKPT----ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPT 753
            ++      S  +PT     + ++P   +  PT+ +E ST   E  T  TE         T
Sbjct: 1720 LAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTE--------TT 1771

Query: 754  ISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPT---------TP 804
            +SP   TT ++  T    K    TE      + PT       + T E            P
Sbjct: 1772 MSPLTNTTTSQGTTRCQPKCEW-TE--WFDVDFPTSGVAGGDMETFENIRAAGGKMCWAP 1828

Query: 805  TEETTISTEKPSIPMEKP----TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP 860
                  +   P + +++     T   E   T   E       +        +  +  +  
Sbjct: 1829 KSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHC 1888

Query: 861  TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920
               P  S       T   T    KPT     TT ST     PT     +P    ++T   
Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTKPT-TTATTTASTGSTATPTSTLRTAPPPKVLTTTAT 1947

Query: 921  TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLT 977
            T     PT+ + + T S+   T   +P  + T +    T  T  P+ S         + T
Sbjct: 1948 T-----PTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTT 2002

Query: 978  IPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHA-PSTPMTSVILGTTTT 1036
             PT   T+ T  P+   E          + T TG    V +P + P T  T+ +  TTTT
Sbjct: 2003 TPT--ATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTT 2060

Query: 1037 SRSSTERCPP 1046
              ++T    P
Sbjct: 2061 GFTATPSSSP 2070



 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 122/546 (22%), Positives = 187/546 (34%), Gaps = 39/546 (7%)

Query: 531  PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEK 590
            PGT     +P        ++   S  T LT    IST     +       +  P      
Sbjct: 2046 PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTA 2105

Query: 591  PTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL-TEKPTIPSEKP-TIPSEKPT 648
              + T   T++T     PS         P++ +   TI  T   T PS  P T P   P 
Sbjct: 2106 TVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPI--PP 2163

Query: 649  ISTEKPTVP--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
            + T   T P  T    TP+    T+   PV  T      T   S+P   P  ++     S
Sbjct: 2164 VLTTTATTPAATSNTVTPSSALGTTHTPPVPNT---MATTHGRSLPPSSPH-TVRTAWTS 2219

Query: 707  TEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKP--TTPTE 764
                 +     T P+   T  T  +T    + +TP      P+ + T SP  P  TTP  
Sbjct: 2220 ATSGILGTTHITEPS-TVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 2278

Query: 765  KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTL 824
                S    T    K    T  P+ PT  P  +        +         S PM  P+ 
Sbjct: 2279 TTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSG 2338

Query: 825  PTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEK-----------PTISPEKLTI 873
               +T +++     +  +  + +E    +  +P +P  +             +   +  +
Sbjct: 2339 GDFDTYSNIRAAGGAVCEQPLGLE--CRAQAQPGVPLRELGQVVECSLDFGLVCRNREQV 2396

Query: 874  PTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEE 933
               K+    E            +   T  T  P+ +P    I TE  T  T   +  +  
Sbjct: 2397 GKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTA 2456

Query: 934  TTISTEKLT-IPTEKPTISPEKLTIPT-EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPT 991
            T  ST   T I TE  T +   +T+PT    T S+ + T  T  ++     PT+ + K T
Sbjct: 2457 TPSSTPGTTWILTEPSTTA--TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT 2514

Query: 992  I-----PTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPP 1046
                      L ALR    +PTAT   A+  S    S   T   L  TTT  ++     P
Sbjct: 2515 PFSSPGTATALPALRSTATTPTATSFTAIPSS----SLGTTWTRLSQTTTPTATMSTATP 2570

Query: 1047 NARYES 1052
            ++  E+
Sbjct: 2571 SSTPET 2576



 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 105/456 (23%), Positives = 160/456 (35%), Gaps = 113/456 (24%)

Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL---G 2280
            C+  C D+D R +GA         C   P  V S     P    GC +A    IPL    
Sbjct: 4976 CNQHC-DID-RFQGA---------CPTSPPPVSSAPLSSPSPAPGCDNA----IPLRQVN 5020

Query: 2281 KSWVSSGCT-EKCVCTGGAI-----QCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQC--S 2332
            ++W    CT  +CV     +        +  C +  H  +   + +  C      +C  S
Sbjct: 5021 ETWTLENCTVARCVGDNRVVLLDPKPVANVTCVN-KHLPIKVSDPSQPCDFHYECECICS 5079

Query: 2333 VYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVI 2392
            ++G   Y TFDG SY  +G  TYVL++ +      +                S++L    
Sbjct: 5080 MWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNL----------------SLYLDNHY 5123

Query: 2393 TTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTL-WGQRLYLVTDFELVVSFGGRKN 2451
             T        +    L ++ + M +       L VT+  G+   L+   ++ VS G  KN
Sbjct: 5124 CTASATAAAARCPRALSIHYKSMDIV------LTVTMVHGKEEGLILFDQIPVSSGFSKN 5177

Query: 2452 AVI-----------------------------SLP-SMYEGLVSGLCGNYDKNRKNDMML 2481
             V+                              LP S++     G CG    N+++D + 
Sbjct: 5178 GVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQ 5237

Query: 2482 PSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS 2541
              G    +      +W V              + ++G  A  G  T    S  +P     
Sbjct: 5238 RDGTTAASCKDMAKTWLVPD------------SRKDGCWAPTG--TPPTASPAAPVSSTP 5283

Query: 2542 NSTQA-----CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSG 2596
              T       C ++      FA CH  V P PF   C+ D C     R + E+ CQ L  
Sbjct: 5284 TPTPCPPQPLCDLMLSQV--FAECHNLVPPGPFFNACISDHC-----RGRLEVPCQSLEA 5336

Query: 2597 YAILCQEAGAALAGWRDRT--LCESPC----LQNPC 2626
            YA LC+  G   + WR  T  LC+  C    +  PC
Sbjct: 5337 YAELCRARGVC-SDWRGATGGLCDLTCPPTKVYKPC 5371



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 80/325 (24%), Positives = 113/325 (34%), Gaps = 49/325 (15%)

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
            CS +GD  Y TFDG  +R  G   YV  +      E     L  G     P      +  
Sbjct: 77   CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP-----VVTR 131

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSF--GG 2448
            V+    G  ++   G  +++N Q+  +PY     L V   G   Y+     LV++F   G
Sbjct: 132  VVIKAQGLVLEASNG-SVLINGQREELPY-SRTGLLVEQSGD--YIKVSIRLVLTFLWNG 187

Query: 2449 RKNAVISLPSMYEGLVSGLCGNYD-KNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLR 2507
              +A++ L   Y     GLCG+++     N+    +  LT     FGN  ++        
Sbjct: 188  EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKLDGPTEQCP 245

Query: 2508 FPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPE 2567
             P  +PA                   C+ E+   +     R L  P   FA CH  V   
Sbjct: 246  DPLPLPA-----------------GNCTDEEGICH-----RTLLGP--AFAECHALVDST 281

Query: 2568 PFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQ 2627
             +   C  DLC            C     Y+  C  AG     WR   LC   C  N   
Sbjct: 282  AYLAACAQDLCRC------PTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNM-- 333

Query: 2628 NDGQCREQGATFTCECEVGYGGGLC 2652
               Q +E G+  T  C       LC
Sbjct: 334  ---QHQECGSPCTDTCSNPQRAQLC 355



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 80/322 (24%), Positives = 124/322 (38%), Gaps = 35/322 (10%)

Query: 756  PEKP-TTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEK 814
            P  P T+ T  P+ +P    I TE  T  T      T + T ST  P++    T I TE 
Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTAT------TTESTGSTATPSSTPGTTWILTEP 2471

Query: 815  PSIPMEKPTLPTEETTT-SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT- 872
             +      T+PT  T T S  + T  T  ++     PT+++ K T     P  SP   T 
Sbjct: 2472 STTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-----PFSSPGTATA 2524

Query: 873  IPTEKLTIPTEKPT----IPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPT 928
            +P  + T  T   T    IP      +  +L+  T  PT +    T S+   T+ T    
Sbjct: 2525 LPALRSTATTPTATSFTAIPSSSLGTTWTRLS-QTTTPTATMSTATPSSTPETVHTSTVL 2583

Query: 929  IPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTE 988
              T  TT +T  +  P+  P  +     + T     +    + P    T+P    T    
Sbjct: 2584 TTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWIST---- 2639

Query: 989  KPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTER--CPP 1046
              T PT + + + P       + +     +P   +T  T+V  G+  T  SST+    PP
Sbjct: 2640 -TTTPTTRGSTVTP-------SSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPP 2691

Query: 1047 NARYESCACPASCKSPRPSCGP 1068
            +    +    A+  +  PS  P
Sbjct: 2692 SLTTTATTITATGSTTNPSSTP 2713



 Score = 55.1 bits (131), Expect = 9e-07
 Identities = 83/314 (26%), Positives = 120/314 (38%), Gaps = 50/314 (15%)

Query: 759  PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818
            P+TP    T +P      T   T    KPT  T   T ST    TPT  +T+ T  P   
Sbjct: 1889 PSTPATSSTATPSS----TPGTTWILTKPTT-TATTTASTGSTATPT--STLRTAPPP-- 1939

Query: 819  MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT-IPTEK 877
                    +  TT+    T+++ K T P   P  +T  P + +   T +   +T IP+  
Sbjct: 1940 --------KVLTTTATTPTVTSSKAT-PSSSPGTATALPALRSTATTPTATSVTPIPSSS 1990

Query: 878  LTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIS 937
            L     +    + +TT  T   T+ T  P+ +PE         T  T      T  TT +
Sbjct: 1991 LGTTWTR----LSQTTTPTA--TMSTATPSSTPE---------TAHTSTVLTATATTTGA 2035

Query: 938  TEKLTIPTEKPTISPEKLTIPTEKPTISTEKP-TIPTEKLTIPTEKPTIPTEKPTIPTEK 996
            T  +  P+  P  +     +PT   T  T  P + P   LT P    T  T  PT     
Sbjct: 2036 TGSVATPSSTPG-TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIST--TTTPTTRGST 2092

Query: 997  LTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTER--CPPNARYESCA 1054
            +T    P  + TAT L          +T  T+V  G+  T  SST+    PP+    +  
Sbjct: 2093 VTPSSIPGTTHTATVL----------TTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT 2142

Query: 1055 CPASCKSPRPSCGP 1068
              A+  +  PS  P
Sbjct: 2143 ITATGSTTNPSSTP 2156



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 15/177 (8%)

Query: 543  PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPK--EKPTIPTEKPTI 600
            PP + + +   + T  L   P   T  P ++   P+ TT  PT+ +    P   +   T 
Sbjct: 1614 PPTTELETATTTTTQALFSTPQ-PTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTA 1672

Query: 601  STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI----PSEKPTISTEKPTV 656
            +T  PT P+      S +PT+P    + L  +  +P    ++    PS+ PT++   PT 
Sbjct: 1673 TTGGPTTPAG-----STEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLA---PTT 1724

Query: 657  PTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
                   PT   +T+ +EP+  +  P++ +E  +   E  T   E T+      T S
Sbjct: 1725 MATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTS 1781



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 53/189 (28%), Positives = 76/189 (40%), Gaps = 27/189 (14%)

Query: 882  TEKPTIPIEETTISTEKLTIPTEKPTISP----EKPTISTEKPTIPTEKPTIPTEETTIS 937
            T  PT  +E  T +T +    T +PT SP      P  +T  PT+ +E  T P   +T+ 
Sbjct: 1612 TPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTL-SEGLTSPRYTSTLG 1670

Query: 938  TEKLTIPT-----EKPTIS-------PEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985
            T     PT      +PT+        P +  +P    ++ T +P+ P      PT  PT 
Sbjct: 1671 TATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQP------PTLAPTT 1724

Query: 986  PTEKPTIPT-EKLTALRPPHPSPTATGLAA-LVMSPHAPSTPMTSVILG--TTTTSRSST 1041
                   PT    TA + P  +  A  L + L  S    STP T   +   T TT+   T
Sbjct: 1725 MATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGT 1784

Query: 1042 ERCPPNARY 1050
             RC P   +
Sbjct: 1785 TRCQPKCEW 1793



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 69/259 (26%), Positives = 91/259 (35%), Gaps = 38/259 (14%)

Query: 471  SPAGSPPIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFI 527
            SP  +   P+W    +  P    ++VT   VP     P  L       + T + VA G +
Sbjct: 3883 SPGTARTPPVWIST-TTTPTTSGSTVTPSSVPGTTHTPTVL-------TTTTTTVATGSM 3934

Query: 528  LI------NPGTCPVKVLPELPPVSPVSSTGPSETTGLTENP-----TISTKKPTVSIEK 576
                      GT P  +       +  S+T PS T G T  P     T +T   T S   
Sbjct: 3935 ATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT 3994

Query: 577  PSV---TTEKPTVPKEKPTI------PTEKPTISTEKPTIPSEKPNMP--SEKPTIPSEK 625
            PS    TT  P VP    T       P+   T+ T   +  S        +E  T  S  
Sbjct: 3995 PSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHT 4054

Query: 626  PTILTEKPTIPSEKPTIPSEKPTI-STEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684
            P   T   T     P + S  P+  +TE P  P+   TTP   T TS         K   
Sbjct: 4055 PAATTG--TTQHSTPALSSPHPSSRTTESP--PSPGTTTPGHTTATSRTTATATPSKTRT 4110

Query: 685  PTEKPSIPTEKPTISMEET 703
             T  PS PT  P  ++  T
Sbjct: 4111 STLLPSSPTSAPITTVVTT 4129



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 44/169 (26%), Positives = 59/169 (34%), Gaps = 15/169 (8%)

Query: 549  SSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIP 608
            S+T PS T G T  P + T   T      S  T    +     T P    T +T   ++P
Sbjct: 3405 STTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTH-TPPVPNTTATTHGRSLP 3463

Query: 609  SEKPNMPSEKPTIPSEK---PTILTEKPTIPSEKP-----TIPSEKPTISTEKPTVPTEE 660
               P+      T  +      T +TE  T+ S  P     T     P +S+  P+  T E
Sbjct: 3464 PSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTE 3523

Query: 661  P------TTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEET 703
                   TTP     TS         K    T  PS PT  P  ++  T
Sbjct: 3524 SPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 3572



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 95/433 (21%), Positives = 140/433 (32%), Gaps = 57/433 (13%)

Query: 759  PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTI----STEEPTTPTEETTIS--- 811
            P  P+  P  SP+     + +P +PT   T  TEK T+    S       T +T  S   
Sbjct: 1434 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGP 1493

Query: 812  -TEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEK-PTISTEKPTIPTEKPTISPE 869
             T  PS P      P  + T   +E    +E+L   +E    I      +  +   I  +
Sbjct: 1494 VTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQ 1553

Query: 870  KLTIPTEKLTIPTEKPTIPI---------EETTISTEKLTIPTEKPTISPE--KPTISTE 918
              + P   L    +K    +         E+  +              S +  +   +T 
Sbjct: 1554 AESFPNWTLAQVGQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTP 1613

Query: 919  KPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTIS--TEKPTIPTEKL 976
             PT   E  T  T +   ST +   PT  P ++       T  PT+S     P   +   
Sbjct: 1614 PPTTELETATTTTTQALFSTPQ---PTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLG 1670

Query: 977  TIPTEKPTIP--TEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH----APSTPMTSVI 1030
            T  T  PT P  + +PT+P    + L      P  TG             AP+T  TS  
Sbjct: 1671 TATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRA 1730

Query: 1031 LGTTTTSRSS----TERCPPNARYESCACPASCKSPR--PSCGPLCREGCVCNPGFLFSD 1084
              T T S +S    T    P    E     A   +PR   +  PL       N       
Sbjct: 1731 RPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPL------TNTTTSQGT 1784

Query: 1085 NHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCR------CWPGSRVECQ--------IS 1130
              C        +++ D+   G         E+ R      CW    +EC+        I 
Sbjct: 1785 TRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSID 1844

Query: 1131 QCGTHTVCQLKNG 1143
            Q G    C L+ G
Sbjct: 1845 QVGQVLTCSLETG 1857



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 654  PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSI---PTEKPTISMEETIISTEKP 710
            P  P+  P T  + + ++  EP +PT   +  TEK ++   P+ + T ++     S+  P
Sbjct: 1434 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGP 1493

Query: 711  -TISPEKPTIPTEKP 724
             T++P  P   T +P
Sbjct: 1494 VTVTPSAPGTTTCQP 1508



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 30/115 (26%), Positives = 35/115 (30%), Gaps = 18/115 (15%)

Query: 1033 TTTTSRSSTERCPPNARYESCAC-PASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQAS 1091
            T T  R+    CP       C C   +C    P C P     C    G       C    
Sbjct: 5470 TVTRPRAENPCCPETV----CVCNTTTCPQSLPVCPPGQESICTQEEG------DCCPTF 5519

Query: 1092 SCN---CFYNNDYYEPGAEWFSPNCTEHCRCWPGS----RVECQISQCGTHTVCQ 1139
             C    C YN  +Y  GA +        C C  G      V+CQ   C   T  Q
Sbjct: 5520 RCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQ 5574


>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2852

 Score =  254 bits (649), Expect = 8e-67
 Identities = 298/1282 (23%), Positives = 471/1282 (36%), Gaps = 250/1282 (19%)

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
            +R +   +C P ++ S   C    +C  +HPA                  C C   N   
Sbjct: 25   ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62

Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
             RCQ               +Y    +  + C A G  H  TFDG  ++  G  +Y L   
Sbjct: 63   PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108

Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
                 Q   F +   N+ + G    +  +AV +  V +  I L +  +V   G RV LP 
Sbjct: 109  HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164

Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
             +   R  ++  +  V++       + +DG+  V + +     G   GLCGN N +  DD
Sbjct: 165  VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222

Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
             +    KL  D ++   +W+    ++P         +P   Q+N  +M   + + C  L+
Sbjct: 223  LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281

Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
             P  PF  CH  V P    ASC    C + GD    CR+L  YA  CAQAG+    WR +
Sbjct: 282  RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339

Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
               C + C   + +Y+ C + CP +C    +PR  C  + + C + C C  G I     C
Sbjct: 340  LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395

Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
            V   +C C +  G+ +P G     +  C   CTC+      C  + C             
Sbjct: 396  VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 440

Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
                     C + G+ H+ +FDG  ++ P  C  +L K    + +   F ++ ++     
Sbjct: 441  ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487

Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
              +   +  V + ++     QVTL +   VL+  +   +P  +       + SS++  V 
Sbjct: 488  NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547

Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
              +GV+V +D   L L +++   +     G+CG FN   +D+ + P     ++   F NS
Sbjct: 548  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607

Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
            WK      +C  L+      P +             L+ A    +A   L   ++A C++
Sbjct: 608  WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653

Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
             +   P+   C    C  G     LC  L  +   C+  GL          C L C A  
Sbjct: 654  FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711

Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
             Y+ C+  C  +C DL        DG  + ++    C EGC C P   L    D CVPR+
Sbjct: 712  EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769

Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
            QC                       CKD        A   + P G+ +V+          
Sbjct: 770  QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 829

Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
                                C   C C  G ++ GD       CP               
Sbjct: 830  SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 889

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            S  H  +    S    +   +  C+ YGD  Y TFDG  +   G     L+K+   +   
Sbjct: 890  SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 949

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
            V   +VE  N      S +  ++ I+        +  G  L+V +     P  P   L  
Sbjct: 950  V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 994

Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
               V  W    + +  F    + + +  R    +     ++G ++GLCGN+D    N+M 
Sbjct: 995  KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054

Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
             P      N   FG+SW  V+  D L   PR +            LR      ECS    
Sbjct: 1055 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1101

Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAI 2599
                     +L++    F  CH  V    F  +C+ D C      +  E  C  +S YA 
Sbjct: 1102 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC-ECFCASVSAYAH 1149

Query: 2600 LCQEAGAALAGWRDRTLCESPC 2621
             C + G A+  WR   LC   C
Sbjct: 1150 QCCQHGVAV-DWRTPRLCPYDC 1170



 Score =  230 bits (586), Expect = 2e-59
 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)

Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
            C  +G  H  TFDG ++   GK +Y L    +P G S    F +   N+ Q G    +C 
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134

Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
              V +  + E  + L K      GG +V LP +         +G +V ++ +    + WD
Sbjct: 135  RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191

Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
            G   +Y+ +S    G   GLCGN + +  +D +   G    D  E  +SWQ         
Sbjct: 192  GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251

Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
                 +  P C      +M G    C  L+    PF+ C  +V    F  SC  D+C   
Sbjct: 252  PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309

Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
            G     C  ++     C  AG  ++ WR +   C + C   +  Y+ C   CP +CH   
Sbjct: 310  GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
            S +     CV+ C C  G +     C+  ++C C     L+P GS         K  C  
Sbjct: 370  SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421

Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
             C C S        W C                A   A C+ +GD H+ TFDG  + F  
Sbjct: 422  TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461

Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
            TC Y+L +   SRS  + F V+  N   G   + + +++V V +       ++L +   V
Sbjct: 462  TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517

Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
            +L      +P +        RLSS  + + TN G++V YD   L + + V   +     G
Sbjct: 518  LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577

Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
            LCG +N N+ DD L P           G +WK   +  P   LV G P   C  +  A +
Sbjct: 578  LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634

Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
            ++ + C++L      F+ C   + P   F  C    C  +     LC +L  YA LC + 
Sbjct: 635  YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690

Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
            G    +R R   C + C     YSPC +PC  TC  + +P  C            C E C
Sbjct: 691  GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750

Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
             C     L   +  CVP  QC C      Y P
Sbjct: 751  ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782



 Score =  179 bits (454), Expect = 3e-44
 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)

Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
            G  T  R  T  C   A  Y  C   CPASC  PR SC      C +GC C  G +F D 
Sbjct: 335  GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393

Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
             C+  + C C ++   Y PG+        E C                    C   +G++
Sbjct: 394  GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430

Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
             C      A C V GD H+ TFDGR + F   C YILA+   + T   F VT +N   G 
Sbjct: 431  ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487

Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
             Q+G +C+  V V L   P   VTL +    L+  Q   +P        +   S  F+ +
Sbjct: 488  NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546

Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
            +T  G+RV +D +  +LY+ V   +     GLCG ++GN+ +D L   G P    +  GN
Sbjct: 547  RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606

Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
            SW+T       C    V  SP   CD  LQ++      C  L  T   F  C   +    
Sbjct: 607  SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659

Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
            +F+ C  D C  +  Q  LC  ++     C+  G  V        C ++C  + +YS C 
Sbjct: 660  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717

Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
             PC  TC    S   C          D CVE C C P   L      C+PR+QC C
Sbjct: 718  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773



 Score =  168 bits (426), Expect = 6e-41
 Identities = 195/782 (24%), Positives = 295/782 (37%), Gaps = 156/782 (19%)

Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
            +C+  G+ H  +FDG  + +    +  LV    P      F I   H   + G+  +   
Sbjct: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134

Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
                  +  +  +     V     +V LP +  +    ++  + Y IV  +    + +DG
Sbjct: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192

Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
               + I++     G   G+CGN N + +D+L+  S ++ +   EFV+SW+++  +    P
Sbjct: 193  ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252

Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
            +  SL       P   Q+NP        ++   E+CEA LR P  A C + +   PF   
Sbjct: 253  TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300

Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
            C + LC+  G     C+AL  +   C   G     WR     C + C   + +Y  C+  
Sbjct: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360

Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
            C  SC      C  +++  AC +GC C  G +  +  CV  ++C C + HG   P G S 
Sbjct: 361  CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415

Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
            V   C   C CT G  +C    CP+                     +CSV GD  + TFD
Sbjct: 416  VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453

Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
            G  Y       Y+L K         T+   P G+  +   V+  + +    PR  + L  
Sbjct: 454  GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
                        QAG  L+ +  K+  PY                 R N  +RV     G
Sbjct: 512  -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560

Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
             RLYL  D   V                      GLCG ++ N ++D + P G       
Sbjct: 561  LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602

Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
             FGNSW+  +                   A   L +G  +  C    Q AS S QAC VL
Sbjct: 603  LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643

Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610
                  FA C   ++P P+ E C  D C    P       C  L+ YA LC+  G  +  
Sbjct: 644  TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRHGLPV-D 695

Query: 2611 WRDR-----TLCE-----SPCLQNPCQNDGQCREQGATFTCECEVG--YGGGLCMEPRDA 2658
            +R R       CE     SPC+  PC     C++  +   C  + G       C+E    
Sbjct: 696  FRARLPACALSCEASKEYSPCVA-PCGR--TCQDLASPEACGVDGGDDLSRDECVEGCAC 752

Query: 2659 PP 2660
            PP
Sbjct: 753  PP 754



 Score =  152 bits (383), Expect = 6e-36
 Identities = 234/1056 (22%), Positives = 367/1056 (34%), Gaps = 235/1056 (22%)

Query: 598  PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
            PT +    T+P      PS+  PT   E+P +  E P  P+ +P +    P T +   P 
Sbjct: 1399 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452

Query: 656  VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
              TEEP      T T++++P+  T  + P+ PTE P+                     + 
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1512

Query: 693  TEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKPT 739
             + PT  M    + T + T+             SP  P  P     +        P + T
Sbjct: 1513 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1572

Query: 740  TPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPTE 785
             P    T  P+ +P  SP      PT         TP     IS   +  PT+  +    
Sbjct: 1573 PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--AS 1630

Query: 786  KPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV--- 833
             P+ P T   T + + P +P      E  +STEK     S PM  P  P      S    
Sbjct: 1631 SPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR 1690

Query: 834  --EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTE 876
              + TT++T    +P E P   ++ST             + T P++  +  P   ++P  
Sbjct: 1691 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1750

Query: 877  KL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP-------- 920
            K+     + T  P   +  T +  +  T+P +  T+SP  P     ++   P        
Sbjct: 1751 KVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPA 1808

Query: 921  -----------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE------ 960
                       T+PT    +P  E T S   +      T K  I  +++++PT       
Sbjct: 1809 AGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAE 1867

Query: 961  ----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP--- 1003
                + T +T  P  P             L +PT          T P + +  L P    
Sbjct: 1868 GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAE 1927

Query: 1004 -HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPA 1057
             H +     LAA         P   S P  S++ G      ++TE               
Sbjct: 1928 AHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA-------------- 1973

Query: 1058 SCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
               +   +C P+  + CV         + C++                 +    N ++HC
Sbjct: 1974 ---NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC 2006

Query: 1118 RCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGK 1177
               P         +CG   +     G   C  +     C ++ D  +VTFDG H     +
Sbjct: 2007 ---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKE 2060

Query: 1178 CTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTL 1232
              YIL+Q    S D    V   + +    G       CL  + +T     VT+ +  R +
Sbjct: 2061 AIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV 2116

Query: 1233 VGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLC 1291
                Q   P +   G  +  +G    + T   ++++W      + V  S T   +  GLC
Sbjct: 2117 TVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLC 2176

Query: 1292 GNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQS 1347
            G  DG++ ND    DGS  G  E+     +SWQ         Q +++  +  + D S   
Sbjct: 2177 GICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP-- 2234

Query: 1348 SMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQ 1407
                   C R+V ++  F  C   V   SF +  + D    Q      C  ++     C 
Sbjct: 2235 -------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCH 2282

Query: 1408 DAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACEC 1462
               H    WR   +CP  C  +S Y  C   C  P TC  G  G    + C    E C C
Sbjct: 2283 KF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVC 2341

Query: 1463 NPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
            + G +L       CIP ++C C    G    +GE W
Sbjct: 2342 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377



 Score =  108 bits (269), Expect = 9e-23
 Identities = 103/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)

Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
            ACP    +  C+    D       TC      +  S R  C+  C C  G +  G  C  
Sbjct: 810  ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869

Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
              +C C      YF  G++   P C   CVC+  +  +C    C                
Sbjct: 870  PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
               A+TCTA GD HY TFDG    F+G C   L +     + D  F V   N N      
Sbjct: 910  ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVN------ 956

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRV---TIRLSSNLVLLYTNF 1652
              Y   +    F +SI++     V  +      P      +    T R+    ++ +   
Sbjct: 957  -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014

Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
             + + +D    V V     + GQL GLCGN++  ++++   P+     +  + G++W   
Sbjct: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074

Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
            + P++ +P           C  N + + +  K C+IL++    F  CH VV     +++C
Sbjct: 1075 ECPDTLDP--------RDMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNC 1124

Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
            +   CG    GD    C S+ AYA  C Q G A  WR    CP  C
Sbjct: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170



 Score =  107 bits (268), Expect = 1e-22
 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)

Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
            SR+    CP    + +C+             C     +   S    C  GC C  G L  
Sbjct: 804  SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863

Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
             + C     C C +    Y PG +  SP                    C T  VCQ  + 
Sbjct: 864  GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902

Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
            Q   HP A  +TC  YGD HY TFDG  F F+G C   L +   +++D  F V  +N   
Sbjct: 903  QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957

Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
               G+ C   + + +  S +          G           + V     G F  +   +
Sbjct: 958  YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013

Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
              + + WD    ++V     + G+L GLCGN+D  + N+    +     + +E G+SW  
Sbjct: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073

Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
             +  D    +   V +P  +   +        C  L+     FE C   V    F+ +C+
Sbjct: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125

Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
             D CG    G     C  +S     C   G AV  WR P  CP  C
Sbjct: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)

Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
            A  C+   D  ++TFDG+         Y+L     S+S D    V   +     +  +++
Sbjct: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090

Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
                              C VMLN     H+V +            PVW    R   R+ 
Sbjct: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135

Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
             + ++ ++ T   +Q+++    G  +VE +  S   G   GLCG  + ++ +D    D  
Sbjct: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193

Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
            + G   D      +W++P SS         +P SC     +      C  +++ +  FS 
Sbjct: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246

Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
            CH+ VPP+S     +        DT  +   C +L  Y ++C +      WR   +CP  
Sbjct: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299

Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
            C   S+Y  C + C  P TC   I  P D        E C C +G IL       C+P  
Sbjct: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359

Query: 1866 QCGCTDPAGSYHPVGERW 1883
            +C CTD  G    +GE W
Sbjct: 2360 KCACTDSMGVPRALGETW 2377



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 86/377 (22%), Positives = 141/377 (37%), Gaps = 60/377 (15%)

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            +G  CQ+       N   ++   C  +G     TFDG  Y L G+ +Y L+   +  PEG
Sbjct: 61   TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
             +   ++  N      S       ++  +  + ++    E+     ++ +P+        
Sbjct: 114  -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172

Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
             L G   Y++   +    +++ G     I +     G   GLCGN + + K+D++  SG 
Sbjct: 173  QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229

Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
            LT ++  F +SW+ +  +          PR  P  ++  G   G+               
Sbjct: 230  LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273

Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600
                + C  L  P  PF ACH  V+P PF   C  DLC +          C+ L+ YA  
Sbjct: 274  ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYARA 325

Query: 2601 CQEAGAALAGWRDR-----TLCES---------PCLQNPCQNDGQC--REQGATFTCECE 2644
            C +AG  L GWR +       C+           C    C     C   E      C C 
Sbjct: 326  CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP 385

Query: 2645 VG--YGGGLCMEPRDAP 2659
             G  +  G C+ P + P
Sbjct: 386  NGLIFEDGGCVAPAECP 402



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)

Query: 569  KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
            +P V +   ++  E     +  PT   E+P +S E P  P+ +P + P+   T     P 
Sbjct: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452

Query: 628  ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
              TE+P +     + T+       +++ P  PTE P   ++  T S+       E  S+P
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510

Query: 686  TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
                 +  + PT  M    + T + T+             SP  P  P     +      
Sbjct: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1565

Query: 733  ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
              P + T P    T  P+ +P  S   P   +  PT S     + T   T    +  +P 
Sbjct: 1566 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1622

Query: 792  EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
                 S   P+TP      + E+         +P     T   E  +STEK      +P 
Sbjct: 1623 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1673

Query: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
             S   P  P   P+  P     P +  T+ T  P +P E  T +   L+  T+    +P 
Sbjct: 1674 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1726

Query: 912  KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
                ST    + +  P     +T++   K  + T  P  +P         P  S     +
Sbjct: 1727 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1772

Query: 972  PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
              +  T+P +  T+    P  P     A  P H +P A G A  L++    P++ +  V 
Sbjct: 1773 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1830

Query: 1031 LGTTT 1035
             GT +
Sbjct: 1831 EGTAS 1835



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)

Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
            CP G  +  CS    D    ++  R C + L         PC   C C +G +  G +C 
Sbjct: 811  CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868

Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
               +C CT     Y P  +     +TC     C   +    FQ T  P            
Sbjct: 869  LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908

Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
            C ++    C   G+ HY +FDG       AC + LVK                       
Sbjct: 909  CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946

Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
              +F +    ++ Y + +  +K   + + +  +     S  P           +   ++G
Sbjct: 947  --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004

Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
                       + + +D    + ++    + G++ G+CGNF+ +  +E+  P +    + 
Sbjct: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064

Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
             EF +SW   +    C   L            +P   C    LR   A+++C + L + V
Sbjct: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107

Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
            +  C   +D+T F  +C      C  GG  +  C ++ A+   C   G+    WR    C
Sbjct: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166

Query: 2208 PLECPAYS 2215
            P +C  ++
Sbjct: 1167 PYDCDFFN 1174



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)

Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
            QVT+ + +R +    Q   P +S+  G  ++ +    ++     +Q+++   + L+ +E 
Sbjct: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164

Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
              T   +  G+CG  + +  ++L +    V   A   + F++SW+     PS  + +   
Sbjct: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220

Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
            +  P          C      R    C   +  P  + C   I  T ++           
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267

Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
               Q  C AL  + A C    +    WR S +CP  C + S+Y  C+ +C P     DG 
Sbjct: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322

Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
              G   P  C    EGC+C  G +L       C+P ++C C D+ G    LG++W S  S
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382

Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
            GC +        I   D  CPS
Sbjct: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 109/472 (23%), Positives = 174/472 (36%), Gaps = 95/472 (20%)

Query: 647  PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
            P +    P  PT +      +    +E+ V P     +PTE     T  P+  +      
Sbjct: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414

Query: 707  TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756
               PT S E+P +  E P  PT +  ++P  P TT    P   TE+P +SP         
Sbjct: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471

Query: 757  -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804
                   + P  PTE P    ++   L IP   E  ++P    T PT        E T  
Sbjct: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530

Query: 805  T------EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPME 848
            T         T+S+  P  P  +  L T+  T          T+  + +++    + P+ 
Sbjct: 1531 TVIFAGSPNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVA 1588

Query: 849  KPTISTEKPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPI 889
             P   +  PT   + K  ++P                 +  + P+  LT+  T    +P+
Sbjct: 1589 SPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPV 1648

Query: 890  EETTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTE 946
                  + ++ + TEK      +P  S   P    +P+  P  P + TT++T    +P E
Sbjct: 1649 SPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPE 1707

Query: 947  KPTISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEK 996
             P  +   L+  T+     P +S E  T P++ L+      ++P  K         P  K
Sbjct: 1708 TPAAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPK 1764

Query: 997  LTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
             + +  P   P AT L A  +SP  P TP         T +   T   PP A
Sbjct: 1765 ASVITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 85/407 (20%), Positives = 143/407 (35%), Gaps = 70/407 (17%)

Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
            +P+   ++G  E     +       C P   ++E  CV      C +     +   +   
Sbjct: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007

Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
                  +C   G A++ G  RC     C                 +CS++ D  ++TFDG
Sbjct: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052

Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
                L     Y+L ++ D +   V  L  +  N      PP   + L     T   ++V 
Sbjct: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108

Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
            +      V  + +   P       R+   G    ++T  ++ + +      +I   S  S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168

Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
              +G   GLCG  D +  ND+ L  G++    ++   F +SW+V             P+ 
Sbjct: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213

Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
                G           ++CSP  ++ SN T            F+ACH+ V PE F E  +
Sbjct: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261

Query: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
             D    Q P       C  L+ Y  +C +    +  WR    C   C
Sbjct: 2262 RDTKYVQQP-------CVALTVYVAMCHKFHVCIE-WRRSDYCPFLC 2300



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)

Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
            C  +  Y  C  P   +C+   SP  +CG           C EGC C P          C
Sbjct: 707  CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765

Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
            +  + C+C +    Y PG          HC C  G
Sbjct: 766  VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798


>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2924

 Score =  254 bits (649), Expect = 8e-67
 Identities = 298/1282 (23%), Positives = 471/1282 (36%), Gaps = 250/1282 (19%)

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
            +R +   +C P ++ S   C    +C  +HPA                  C C   N   
Sbjct: 97   ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 134

Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
             RCQ               +Y    +  + C A G  H  TFDG  ++  G  +Y L   
Sbjct: 135  PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180

Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
                 Q   F +   N+ + G    +  +AV +  V +  I L +  +V   G RV LP 
Sbjct: 181  HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 236

Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
             +   R  ++  +  V++       + +DG+  V + +     G   GLCGN N +  DD
Sbjct: 237  VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 294

Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
             +    KL  D ++   +W+    ++P         +P   Q+N  +M   + + C  L+
Sbjct: 295  LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 353

Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
             P  PF  CH  V P    ASC    C + GD    CR+L  YA  CAQAG+    WR +
Sbjct: 354  RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411

Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
               C + C   + +Y+ C + CP +C    +PR  C  + + C + C C  G I     C
Sbjct: 412  LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 467

Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
            V   +C C +  G+ +P G     +  C   CTC+      C  + C             
Sbjct: 468  VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 512

Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
                     C + G+ H+ +FDG  ++ P  C  +L K    + +   F ++ ++     
Sbjct: 513  ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 559

Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
              +   +  V + ++     QVTL +   VL+  +   +P  +       + SS++  V 
Sbjct: 560  NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 619

Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
              +GV+V +D   L L +++   +     G+CG FN   +D+ + P     ++   F NS
Sbjct: 620  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679

Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
            WK      +C  L+      P +             L+ A    +A   L   ++A C++
Sbjct: 680  WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 725

Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
             +   P+   C    C  G     LC  L  +   C+  GL          C L C A  
Sbjct: 726  FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 783

Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
             Y+ C+  C  +C DL        DG  + ++    C EGC C P   L    D CVPR+
Sbjct: 784  EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 841

Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
            QC                       CKD        A   + P G+ +V+          
Sbjct: 842  QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 901

Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
                                C   C C  G ++ GD       CP               
Sbjct: 902  SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 961

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            S  H  +    S    +   +  C+ YGD  Y TFDG  +   G     L+K+   +   
Sbjct: 962  SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 1021

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
            V   +VE  N      S +  ++ I+        +  G  L+V +     P  P   L  
Sbjct: 1022 V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 1066

Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
               V  W    + +  F    + + +  R    +     ++G ++GLCGN+D    N+M 
Sbjct: 1067 KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1126

Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
             P      N   FG+SW  V+  D L   PR +            LR      ECS    
Sbjct: 1127 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1173

Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAI 2599
                     +L++    F  CH  V    F  +C+ D C      +  E  C  +S YA 
Sbjct: 1174 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC-ECFCASVSAYAH 1221

Query: 2600 LCQEAGAALAGWRDRTLCESPC 2621
             C + G A+  WR   LC   C
Sbjct: 1222 QCCQHGVAV-DWRTPRLCPYDC 1242



 Score =  230 bits (586), Expect = 2e-59
 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)

Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
            C  +G  H  TFDG ++   GK +Y L    +P G S    F +   N+ Q G    +C 
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 206

Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
              V +  + E  + L K      GG +V LP +         +G +V ++ +    + WD
Sbjct: 207  RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 263

Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
            G   +Y+ +S    G   GLCGN + +  +D +   G    D  E  +SWQ         
Sbjct: 264  GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 323

Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
                 +  P C      +M G    C  L+    PF+ C  +V    F  SC  D+C   
Sbjct: 324  PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 381

Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
            G     C  ++     C  AG  ++ WR +   C + C   +  Y+ C   CP +CH   
Sbjct: 382  GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 441

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
            S +     CV+ C C  G +     C+  ++C C     L+P GS         K  C  
Sbjct: 442  SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 493

Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
             C C S        W C                A   A C+ +GD H+ TFDG  + F  
Sbjct: 494  TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 533

Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
            TC Y+L +   SRS  + F V+  N   G   + + +++V V +       ++L +   V
Sbjct: 534  TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 589

Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
            +L      +P +        RLSS  + + TN G++V YD   L + + V   +     G
Sbjct: 590  LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 649

Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
            LCG +N N+ DD L P           G +WK   +  P   LV G P   C  +  A +
Sbjct: 650  LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 706

Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
            ++ + C++L      F+ C   + P   F  C    C  +     LC +L  YA LC + 
Sbjct: 707  YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 762

Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
            G    +R R   C + C     YSPC +PC  TC  + +P  C            C E C
Sbjct: 763  GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 822

Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
             C     L   +  CVP  QC C      Y P
Sbjct: 823  ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 854



 Score =  179 bits (454), Expect = 3e-44
 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)

Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
            G  T  R  T  C   A  Y  C   CPASC  PR SC      C +GC C  G +F D 
Sbjct: 407  GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 465

Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
             C+  + C C ++   Y PG+        E C                    C   +G++
Sbjct: 466  GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 502

Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
             C      A C V GD H+ TFDGR + F   C YILA+   + T   F VT +N   G 
Sbjct: 503  ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 559

Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
             Q+G +C+  V V L   P   VTL +    L+  Q   +P        +   S  F+ +
Sbjct: 560  NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 618

Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
            +T  G+RV +D +  +LY+ V   +     GLCG ++GN+ +D L   G P    +  GN
Sbjct: 619  RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 678

Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
            SW+T       C    V  SP   CD  LQ++      C  L  T   F  C   +    
Sbjct: 679  SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 731

Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
            +F+ C  D C  +  Q  LC  ++     C+  G  V        C ++C  + +YS C 
Sbjct: 732  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789

Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
             PC  TC    S   C          D CVE C C P   L      C+PR+QC C
Sbjct: 790  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845



 Score =  168 bits (426), Expect = 6e-41
 Identities = 195/782 (24%), Positives = 295/782 (37%), Gaps = 156/782 (19%)

Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
            +C+  G+ H  +FDG  + +    +  LV    P      F I   H   + G+  +   
Sbjct: 150  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 206

Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
                  +  +  +     V     +V LP +  +    ++  + Y IV  +    + +DG
Sbjct: 207  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 264

Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
               + I++     G   G+CGN N + +D+L+  S ++ +   EFV+SW+++  +    P
Sbjct: 265  ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 324

Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
            +  SL       P   Q+NP        ++   E+CEA LR P  A C + +   PF   
Sbjct: 325  TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 372

Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
            C + LC+  G     C+AL  +   C   G     WR     C + C   + +Y  C+  
Sbjct: 373  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432

Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
            C  SC      C  +++  AC +GC C  G +  +  CV  ++C C + HG   P G S 
Sbjct: 433  CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 487

Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
            V   C   C CT G  +C    CP+                     +CSV GD  + TFD
Sbjct: 488  VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 525

Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
            G  Y       Y+L K         T+   P G+  +   V+  + +    PR  + L  
Sbjct: 526  GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 583

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
                        QAG  L+ +  K+  PY                 R N  +RV     G
Sbjct: 584  -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632

Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
             RLYL  D   V                      GLCG ++ N ++D + P G       
Sbjct: 633  LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 674

Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
             FGNSW+  +                   A   L +G  +  C    Q AS S QAC VL
Sbjct: 675  LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 715

Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610
                  FA C   ++P P+ E C  D C    P       C  L+ YA LC+  G  +  
Sbjct: 716  TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRHGLPV-D 767

Query: 2611 WRDR-----TLCE-----SPCLQNPCQNDGQCREQGATFTCECEVG--YGGGLCMEPRDA 2658
            +R R       CE     SPC+  PC     C++  +   C  + G       C+E    
Sbjct: 768  FRARLPACALSCEASKEYSPCVA-PCGR--TCQDLASPEACGVDGGDDLSRDECVEGCAC 824

Query: 2659 PP 2660
            PP
Sbjct: 825  PP 826



 Score =  152 bits (383), Expect = 6e-36
 Identities = 234/1056 (22%), Positives = 367/1056 (34%), Gaps = 235/1056 (22%)

Query: 598  PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
            PT +    T+P      PS+  PT   E+P +  E P  P+ +P +    P T +   P 
Sbjct: 1471 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524

Query: 656  VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
              TEEP      T T++++P+  T  + P+ PTE P+                     + 
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1584

Query: 693  TEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKPT 739
             + PT  M    + T + T+             SP  P  P     +        P + T
Sbjct: 1585 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1644

Query: 740  TPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPTE 785
             P    T  P+ +P  SP      PT         TP     IS   +  PT+  +    
Sbjct: 1645 PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--AS 1702

Query: 786  KPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV--- 833
             P+ P T   T + + P +P      E  +STEK     S PM  P  P      S    
Sbjct: 1703 SPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR 1762

Query: 834  --EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTE 876
              + TT++T    +P E P   ++ST             + T P++  +  P   ++P  
Sbjct: 1763 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1822

Query: 877  KL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP-------- 920
            K+     + T  P   +  T +  +  T+P +  T+SP  P     ++   P        
Sbjct: 1823 KVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPA 1880

Query: 921  -----------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE------ 960
                       T+PT    +P  E T S   +      T K  I  +++++PT       
Sbjct: 1881 AGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAE 1939

Query: 961  ----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP--- 1003
                + T +T  P  P             L +PT          T P + +  L P    
Sbjct: 1940 GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAE 1999

Query: 1004 -HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPA 1057
             H +     LAA         P   S P  S++ G      ++TE               
Sbjct: 2000 AHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA-------------- 2045

Query: 1058 SCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
               +   +C P+  + CV         + C++                 +    N ++HC
Sbjct: 2046 ---NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC 2078

Query: 1118 RCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGK 1177
               P         +CG   +     G   C  +     C ++ D  +VTFDG H     +
Sbjct: 2079 ---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKE 2132

Query: 1178 CTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTL 1232
              YIL+Q    S D    V   + +    G       CL  + +T     VT+ +  R +
Sbjct: 2133 AIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV 2188

Query: 1233 VGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLC 1291
                Q   P +   G  +  +G    + T   ++++W      + V  S T   +  GLC
Sbjct: 2189 TVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLC 2248

Query: 1292 GNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQS 1347
            G  DG++ ND    DGS  G  E+     +SWQ         Q +++  +  + D S   
Sbjct: 2249 GICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP-- 2306

Query: 1348 SMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQ 1407
                   C R+V ++  F  C   V   SF +  + D    Q      C  ++     C 
Sbjct: 2307 -------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCH 2354

Query: 1408 DAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACEC 1462
               H    WR   +CP  C  +S Y  C   C  P TC  G  G    + C    E C C
Sbjct: 2355 KF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVC 2413

Query: 1463 NPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
            + G +L       CIP ++C C    G    +GE W
Sbjct: 2414 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449



 Score =  108 bits (269), Expect = 9e-23
 Identities = 103/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)

Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
            ACP    +  C+    D       TC      +  S R  C+  C C  G +  G  C  
Sbjct: 882  ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 941

Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
              +C C      YF  G++   P C   CVC+  +  +C    C                
Sbjct: 942  PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 981

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
               A+TCTA GD HY TFDG    F+G C   L +     + D  F V   N N      
Sbjct: 982  ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVN------ 1028

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRV---TIRLSSNLVLLYTNF 1652
              Y   +    F +SI++     V  +      P      +    T R+    ++ +   
Sbjct: 1029 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1086

Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
             + + +D    V V     + GQL GLCGN++  ++++   P+     +  + G++W   
Sbjct: 1087 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1146

Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
            + P++ +P           C  N + + +  K C+IL++    F  CH VV     +++C
Sbjct: 1147 ECPDTLDP--------RDMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNC 1196

Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
            +   CG    GD    C S+ AYA  C Q G A  WR    CP  C
Sbjct: 1197 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242



 Score =  107 bits (268), Expect = 1e-22
 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)

Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
            SR+    CP    + +C+             C     +   S    C  GC C  G L  
Sbjct: 876  SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 935

Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
             + C     C C +    Y PG +  SP                    C T  VCQ  + 
Sbjct: 936  GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 974

Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
            Q   HP A  +TC  YGD HY TFDG  F F+G C   L +   +++D  F V  +N   
Sbjct: 975  QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 1029

Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
               G+ C   + + +  S +          G           + V     G F  +   +
Sbjct: 1030 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085

Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
              + + WD    ++V     + G+L GLCGN+D  + N+    +     + +E G+SW  
Sbjct: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145

Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
             +  D    +   V +P  +   +        C  L+     FE C   V    F+ +C+
Sbjct: 1146 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1197

Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
             D CG    G     C  +S     C   G AV  WR P  CP  C
Sbjct: 1198 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)

Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
            A  C+   D  ++TFDG+         Y+L     S+S D    V   +     +  +++
Sbjct: 2108 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2162

Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
                              C VMLN     H+V +            PVW    R   R+ 
Sbjct: 2163 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2207

Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
             + ++ ++ T   +Q+++    G  +VE +  S   G   GLCG  + ++ +D    D  
Sbjct: 2208 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2265

Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
            + G   D      +W++P SS         +P SC     +      C  +++ +  FS 
Sbjct: 2266 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2318

Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
            CH+ VPP+S     +        DT  +   C +L  Y ++C +      WR   +CP  
Sbjct: 2319 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371

Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
            C   S+Y  C + C  P TC   I  P D        E C C +G IL       C+P  
Sbjct: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431

Query: 1866 QCGCTDPAGSYHPVGERW 1883
            +C CTD  G    +GE W
Sbjct: 2432 KCACTDSMGVPRALGETW 2449



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 86/377 (22%), Positives = 141/377 (37%), Gaps = 60/377 (15%)

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            +G  CQ+       N   ++   C  +G     TFDG  Y L G+ +Y L+   +  PEG
Sbjct: 133  TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 185

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
             +   ++  N      S       ++  +  + ++    E+     ++ +P+        
Sbjct: 186  -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 244

Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
             L G   Y++   +    +++ G     I +     G   GLCGN + + K+D++  SG 
Sbjct: 245  QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 301

Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
            LT ++  F +SW+ +  +          PR  P  ++  G   G+               
Sbjct: 302  LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 345

Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600
                + C  L  P  PF ACH  V+P PF   C  DLC +          C+ L+ YA  
Sbjct: 346  ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYARA 397

Query: 2601 CQEAGAALAGWRDR-----TLCES---------PCLQNPCQNDGQC--REQGATFTCECE 2644
            C +AG  L GWR +       C+           C    C     C   E      C C 
Sbjct: 398  CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP 457

Query: 2645 VG--YGGGLCMEPRDAP 2659
             G  +  G C+ P + P
Sbjct: 458  NGLIFEDGGCVAPAECP 474



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)

Query: 569  KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
            +P V +   ++  E     +  PT   E+P +S E P  P+ +P + P+   T     P 
Sbjct: 1465 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524

Query: 628  ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
              TE+P +     + T+       +++ P  PTE P   ++  T S+       E  S+P
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1582

Query: 686  TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
                 +  + PT  M    + T + T+             SP  P  P     +      
Sbjct: 1583 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1637

Query: 733  ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
              P + T P    T  P+ +P  S   P   +  PT S     + T   T    +  +P 
Sbjct: 1638 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1694

Query: 792  EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
                 S   P+TP      + E+         +P     T   E  +STEK      +P 
Sbjct: 1695 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1745

Query: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
             S   P  P   P+  P     P +  T+ T  P +P E  T +   L+  T+    +P 
Sbjct: 1746 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1798

Query: 912  KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
                ST    + +  P     +T++   K  + T  P  +P         P  S     +
Sbjct: 1799 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1844

Query: 972  PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
              +  T+P +  T+    P  P     A  P H +P A G A  L++    P++ +  V 
Sbjct: 1845 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1902

Query: 1031 LGTTT 1035
             GT +
Sbjct: 1903 EGTAS 1907



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)

Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
            CP G  +  CS    D    ++  R C + L         PC   C C +G +  G +C 
Sbjct: 883  CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940

Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
               +C CT     Y P  +     +TC     C   +    FQ T  P            
Sbjct: 941  LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 980

Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
            C ++    C   G+ HY +FDG       AC + LVK                       
Sbjct: 981  CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 1018

Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
              +F +    ++ Y + +  +K   + + +  +     S  P           +   ++G
Sbjct: 1019 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076

Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
                       + + +D    + ++    + G++ G+CGNF+ +  +E+  P +    + 
Sbjct: 1077 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1136

Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
             EF +SW   +    C   L            +P   C    LR   A+++C + L + V
Sbjct: 1137 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1179

Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
            +  C   +D+T F  +C      C  GG  +  C ++ A+   C   G+    WR    C
Sbjct: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1238

Query: 2208 PLECPAYS 2215
            P +C  ++
Sbjct: 1239 PYDCDFFN 1246



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)

Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
            QVT+ + +R +    Q   P +S+  G  ++ +    ++     +Q+++   + L+ +E 
Sbjct: 2178 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2236

Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
              T   +  G+CG  + +  ++L +    V   A   + F++SW+     PS  + +   
Sbjct: 2237 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2292

Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
            +  P          C      R    C   +  P  + C   I  T ++           
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2339

Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
               Q  C AL  + A C    +    WR S +CP  C + S+Y  C+ +C P     DG 
Sbjct: 2340 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2394

Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
              G   P  C    EGC+C  G +L       C+P ++C C D+ G    LG++W S  S
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454

Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
            GC +        I   D  CPS
Sbjct: 2455 GCCQHQCQAPDTIVPVDLGCPS 2476



 Score = 74.3 bits (181), Expect = 2e-12
 Identities = 108/465 (23%), Positives = 172/465 (36%), Gaps = 95/465 (20%)

Query: 654  PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
            P  PT +      +    +E+ V P     +PTE     T  P+  +         PT S
Sbjct: 1442 PVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL---------PTPS 1490

Query: 714  PEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP---------------- 756
             E+P +  E P  PT +  ++P  P TT    P   TE+P +SP                
Sbjct: 1491 DEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTAS 1550

Query: 757  EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTPT------ 805
            + P  PTE P    ++   L IP   E  ++P    T PT        E T  T      
Sbjct: 1551 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRVTVIFAGS 1609

Query: 806  EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPMEKPTISTE 855
               T+S+  P  P  +  L T+  T          T+  + +++    + P+  P   + 
Sbjct: 1610 PNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISR 1667

Query: 856  KPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEETTIST 896
             PT   + K  ++P                 +  + P+  LT+  T    +P+      +
Sbjct: 1668 SPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1727

Query: 897  EKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
             ++ + TEK      +P  S   P    +P+  P  P + TT++T    +P E P  +  
Sbjct: 1728 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETPAAA-- 1784

Query: 954  KLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLTALRPP 1003
             L+  T+     P +S E  T P++ L+      ++P  K         P  K + +  P
Sbjct: 1785 SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTP 1843

Query: 1004 HPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
               P AT L A  +SP  P TP         T +   T   PP A
Sbjct: 1844 -LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1881



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 85/407 (20%), Positives = 143/407 (35%), Gaps = 70/407 (17%)

Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
            +P+   ++G  E     +       C P   ++E  CV      C +     +   +   
Sbjct: 2026 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2079

Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
                  +C   G A++ G  RC     C                 +CS++ D  ++TFDG
Sbjct: 2080 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2124

Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
                L     Y+L ++ D +   V  L  +  N      PP   + L     T   ++V 
Sbjct: 2125 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2180

Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
            +      V  + +   P       R+   G    ++T  ++ + +      +I   S  S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240

Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
              +G   GLCG  D +  ND+ L  G++    ++   F +SW+V             P+ 
Sbjct: 2241 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2285

Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
                G           ++CSP  ++ SN T            F+ACH+ V PE F E  +
Sbjct: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2333

Query: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
             D    Q P       C  L+ Y  +C +    +  WR    C   C
Sbjct: 2334 RDTKYVQQP-------CVALTVYVAMCHKFHVCIE-WRRSDYCPFLC 2372



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)

Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
            C  +  Y  C  P   +C+   SP  +CG           C EGC C P          C
Sbjct: 779  CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837

Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
            +  + C+C +    Y PG          HC C  G
Sbjct: 838  VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 870


>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  254 bits (649), Expect = 8e-67
 Identities = 298/1282 (23%), Positives = 471/1282 (36%), Gaps = 250/1282 (19%)

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
            +R +   +C P ++ S   C    +C  +HPA                  C C   N   
Sbjct: 25   ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62

Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
             RCQ               +Y    +  + C A G  H  TFDG  ++  G  +Y L   
Sbjct: 63   PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108

Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
                 Q   F +   N+ + G    +  +AV +  V +  I L +  +V   G RV LP 
Sbjct: 109  HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164

Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
             +   R  ++  +  V++       + +DG+  V + +     G   GLCGN N +  DD
Sbjct: 165  VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222

Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
             +    KL  D ++   +W+    ++P         +P   Q+N  +M   + + C  L+
Sbjct: 223  LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281

Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
             P  PF  CH  V P    ASC    C + GD    CR+L  YA  CAQAG+    WR +
Sbjct: 282  RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339

Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
               C + C   + +Y+ C + CP +C    +PR  C  + + C + C C  G I     C
Sbjct: 340  LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395

Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
            V   +C C +  G+ +P G     +  C   CTC+      C  + C             
Sbjct: 396  VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 440

Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
                     C + G+ H+ +FDG  ++ P  C  +L K    + +   F ++ ++     
Sbjct: 441  ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487

Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
              +   +  V + ++     QVTL +   VL+  +   +P  +       + SS++  V 
Sbjct: 488  NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547

Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
              +GV+V +D   L L +++   +     G+CG FN   +D+ + P     ++   F NS
Sbjct: 548  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607

Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
            WK      +C  L+      P +             L+ A    +A   L   ++A C++
Sbjct: 608  WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653

Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
             +   P+   C    C  G     LC  L  +   C+  GL          C L C A  
Sbjct: 654  FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711

Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
             Y+ C+  C  +C DL        DG  + ++    C EGC C P   L    D CVPR+
Sbjct: 712  EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769

Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
            QC                       CKD        A   + P G+ +V+          
Sbjct: 770  QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 829

Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
                                C   C C  G ++ GD       CP               
Sbjct: 830  SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 889

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            S  H  +    S    +   +  C+ YGD  Y TFDG  +   G     L+K+   +   
Sbjct: 890  SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 949

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
            V   +VE  N      S +  ++ I+        +  G  L+V +     P  P   L  
Sbjct: 950  V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 994

Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
               V  W    + +  F    + + +  R    +     ++G ++GLCGN+D    N+M 
Sbjct: 995  KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054

Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
             P      N   FG+SW  V+  D L   PR +            LR      ECS    
Sbjct: 1055 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1101

Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAI 2599
                     +L++    F  CH  V    F  +C+ D C      +  E  C  +S YA 
Sbjct: 1102 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC-ECFCASVSAYAH 1149

Query: 2600 LCQEAGAALAGWRDRTLCESPC 2621
             C + G A+  WR   LC   C
Sbjct: 1150 QCCQHGVAV-DWRTPRLCPYDC 1170



 Score =  230 bits (586), Expect = 2e-59
 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)

Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
            C  +G  H  TFDG ++   GK +Y L    +P G S    F +   N+ Q G    +C 
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134

Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
              V +  + E  + L K      GG +V LP +         +G +V ++ +    + WD
Sbjct: 135  RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191

Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
            G   +Y+ +S    G   GLCGN + +  +D +   G    D  E  +SWQ         
Sbjct: 192  GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251

Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
                 +  P C      +M G    C  L+    PF+ C  +V    F  SC  D+C   
Sbjct: 252  PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309

Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
            G     C  ++     C  AG  ++ WR +   C + C   +  Y+ C   CP +CH   
Sbjct: 310  GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
            S +     CV+ C C  G +     C+  ++C C     L+P GS         K  C  
Sbjct: 370  SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421

Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
             C C S        W C                A   A C+ +GD H+ TFDG  + F  
Sbjct: 422  TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461

Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
            TC Y+L +   SRS  + F V+  N   G   + + +++V V +       ++L +   V
Sbjct: 462  TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517

Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
            +L      +P +        RLSS  + + TN G++V YD   L + + V   +     G
Sbjct: 518  LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577

Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
            LCG +N N+ DD L P           G +WK   +  P   LV G P   C  +  A +
Sbjct: 578  LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634

Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
            ++ + C++L      F+ C   + P   F  C    C  +     LC +L  YA LC + 
Sbjct: 635  YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690

Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
            G    +R R   C + C     YSPC +PC  TC  + +P  C            C E C
Sbjct: 691  GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750

Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
             C     L   +  CVP  QC C      Y P
Sbjct: 751  ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782



 Score =  179 bits (454), Expect = 3e-44
 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)

Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
            G  T  R  T  C   A  Y  C   CPASC  PR SC      C +GC C  G +F D 
Sbjct: 335  GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393

Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
             C+  + C C ++   Y PG+        E C                    C   +G++
Sbjct: 394  GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430

Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
             C      A C V GD H+ TFDGR + F   C YILA+   + T   F VT +N   G 
Sbjct: 431  ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487

Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
             Q+G +C+  V V L   P   VTL +    L+  Q   +P        +   S  F+ +
Sbjct: 488  NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546

Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
            +T  G+RV +D +  +LY+ V   +     GLCG ++GN+ +D L   G P    +  GN
Sbjct: 547  RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606

Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
            SW+T       C    V  SP   CD  LQ++      C  L  T   F  C   +    
Sbjct: 607  SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659

Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
            +F+ C  D C  +  Q  LC  ++     C+  G  V        C ++C  + +YS C 
Sbjct: 660  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717

Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
             PC  TC    S   C          D CVE C C P   L      C+PR+QC C
Sbjct: 718  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773



 Score =  168 bits (426), Expect = 6e-41
 Identities = 195/782 (24%), Positives = 295/782 (37%), Gaps = 156/782 (19%)

Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
            +C+  G+ H  +FDG  + +    +  LV    P      F I   H   + G+  +   
Sbjct: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134

Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
                  +  +  +     V     +V LP +  +    ++  + Y IV  +    + +DG
Sbjct: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192

Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
               + I++     G   G+CGN N + +D+L+  S ++ +   EFV+SW+++  +    P
Sbjct: 193  ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252

Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
            +  SL       P   Q+NP        ++   E+CEA LR P  A C + +   PF   
Sbjct: 253  TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300

Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
            C + LC+  G     C+AL  +   C   G     WR     C + C   + +Y  C+  
Sbjct: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360

Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
            C  SC      C  +++  AC +GC C  G +  +  CV  ++C C + HG   P G S 
Sbjct: 361  CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415

Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
            V   C   C CT G  +C    CP+                     +CSV GD  + TFD
Sbjct: 416  VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453

Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
            G  Y       Y+L K         T+   P G+  +   V+  + +    PR  + L  
Sbjct: 454  GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
                        QAG  L+ +  K+  PY                 R N  +RV     G
Sbjct: 512  -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560

Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
             RLYL  D   V                      GLCG ++ N ++D + P G       
Sbjct: 561  LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602

Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
             FGNSW+  +                   A   L +G  +  C    Q AS S QAC VL
Sbjct: 603  LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643

Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610
                  FA C   ++P P+ E C  D C    P       C  L+ YA LC+  G  +  
Sbjct: 644  TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRHGLPV-D 695

Query: 2611 WRDR-----TLCE-----SPCLQNPCQNDGQCREQGATFTCECEVG--YGGGLCMEPRDA 2658
            +R R       CE     SPC+  PC     C++  +   C  + G       C+E    
Sbjct: 696  FRARLPACALSCEASKEYSPCVA-PCGR--TCQDLASPEACGVDGGDDLSRDECVEGCAC 752

Query: 2659 PP 2660
            PP
Sbjct: 753  PP 754



 Score =  150 bits (380), Expect = 1e-35
 Identities = 230/1054 (21%), Positives = 366/1054 (34%), Gaps = 231/1054 (21%)

Query: 598  PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
            PT +    T+P      PS+  PT   E+P +  E P  P+ +P +    P T +   P 
Sbjct: 1399 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452

Query: 656  VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
              TEEP      T T++++P+  T  + P+ PTE P+                     + 
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1512

Query: 693  TEKPTISMEETIISTEKPTI-------------SPEKPTIP--TEKPTI------PTEKS 731
             + PT  M    + T + T+             SP  P  P  T+  T+      P   +
Sbjct: 1513 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1572

Query: 732  TISPEKPTTPTEKPTIP----TEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKP 787
             + P    +P+ +P       +  PT S       T   T    +  +P          P
Sbjct: 1573 PLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSP 1632

Query: 788  TIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV----- 833
            + P T   T + + P +P      E  +STEK     S PM  P  P      S      
Sbjct: 1633 STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPA 1692

Query: 834  EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTEKL 878
            + TT++T    +P E P   ++ST             + T P++  +  P   ++P  K+
Sbjct: 1693 QHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKV 1752

Query: 879  ----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP---------- 920
                 + T  P   +  T +  +  T+P +  T+SP  P     ++   P          
Sbjct: 1753 GTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAG 1810

Query: 921  ---------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE-------- 960
                     T+PT    +P  E T S   +      T K  I  +++++PT         
Sbjct: 1811 TAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGG 1869

Query: 961  --KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP----H 1004
              + T +T  P  P             L +PT          T P + +  L P     H
Sbjct: 1870 PTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH 1929

Query: 1005 PSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASC 1059
             +     LAA         P   S P  S++ G      ++TE                 
Sbjct: 1930 GTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA---------------- 1973

Query: 1060 KSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRC 1119
             +   +C P+  + CV         + C++                 +    N ++HC  
Sbjct: 1974 -NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC-- 2006

Query: 1120 WPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCT 1179
             P         +CG   +     G   C  +     C ++ D  +VTFDG H     +  
Sbjct: 2007 -PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAI 2062

Query: 1180 YILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTLVG 1234
            YIL+Q    S D    V   + +    G       CL  + +T     VT+ +  R +  
Sbjct: 2063 YILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTV 2118

Query: 1235 GQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLCGN 1293
              Q   P +   G  +  +G    + T   ++++W      + V  S T   +  GLCG 
Sbjct: 2119 DLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGI 2178

Query: 1294 YDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSM 1349
             DG++ ND    DGS  G  E+     +SWQ         Q +++  +  + D S     
Sbjct: 2179 CDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP---- 2234

Query: 1350 SGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDA 1409
                 C R+V ++  F  C   V   SF +  + D    Q      C  ++     C   
Sbjct: 2235 -----CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCHKF 2284

Query: 1410 GHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACECNP 1464
             H    WR   +CP  C  +S Y  C   C  P TC  G  G    + C    E C C+ 
Sbjct: 2285 -HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSE 2343

Query: 1465 GFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
            G +L       CIP ++C C    G    +GE W
Sbjct: 2344 GTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377



 Score =  108 bits (269), Expect = 9e-23
 Identities = 103/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)

Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
            ACP    +  C+    D       TC      +  S R  C+  C C  G +  G  C  
Sbjct: 810  ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869

Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
              +C C      YF  G++   P C   CVC+  +  +C    C                
Sbjct: 870  PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
               A+TCTA GD HY TFDG    F+G C   L +     + D  F V   N N      
Sbjct: 910  ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVN------ 956

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRV---TIRLSSNLVLLYTNF 1652
              Y   +    F +SI++     V  +      P      +    T R+    ++ +   
Sbjct: 957  -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014

Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
             + + +D    V V     + GQL GLCGN++  ++++   P+     +  + G++W   
Sbjct: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074

Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
            + P++ +P           C  N + + +  K C+IL++    F  CH VV     +++C
Sbjct: 1075 ECPDTLDP--------RDMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNC 1124

Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
            +   CG    GD    C S+ AYA  C Q G A  WR    CP  C
Sbjct: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170



 Score =  107 bits (268), Expect = 1e-22
 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)

Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
            SR+    CP    + +C+             C     +   S    C  GC C  G L  
Sbjct: 804  SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863

Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
             + C     C C +    Y PG +  SP                    C T  VCQ  + 
Sbjct: 864  GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902

Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
            Q   HP A  +TC  YGD HY TFDG  F F+G C   L +   +++D  F V  +N   
Sbjct: 903  QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957

Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
               G+ C   + + +  S +          G           + V     G F  +   +
Sbjct: 958  YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013

Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
              + + WD    ++V     + G+L GLCGN+D  + N+    +     + +E G+SW  
Sbjct: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073

Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
             +  D    +   V +P  +   +        C  L+     FE C   V    F+ +C+
Sbjct: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125

Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
             D CG    G     C  +S     C   G AV  WR P  CP  C
Sbjct: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)

Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
            A  C+   D  ++TFDG+         Y+L     S+S D    V   +     +  +++
Sbjct: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090

Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
                              C VMLN     H+V +            PVW    R   R+ 
Sbjct: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135

Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
             + ++ ++ T   +Q+++    G  +VE +  S   G   GLCG  + ++ +D    D  
Sbjct: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193

Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
            + G   D      +W++P SS         +P SC     +      C  +++ +  FS 
Sbjct: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246

Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
            CH+ VPP+S     +        DT  +   C +L  Y ++C +      WR   +CP  
Sbjct: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299

Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
            C   S+Y  C + C  P TC   I  P D        E C C +G IL       C+P  
Sbjct: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359

Query: 1866 QCGCTDPAGSYHPVGERW 1883
            +C CTD  G    +GE W
Sbjct: 2360 KCACTDSMGVPRALGETW 2377



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 86/377 (22%), Positives = 141/377 (37%), Gaps = 60/377 (15%)

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            +G  CQ+       N   ++   C  +G     TFDG  Y L G+ +Y L+   +  PEG
Sbjct: 61   TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
             +   ++  N      S       ++  +  + ++    E+     ++ +P+        
Sbjct: 114  -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172

Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
             L G   Y++   +    +++ G     I +     G   GLCGN + + K+D++  SG 
Sbjct: 173  QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229

Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
            LT ++  F +SW+ +  +          PR  P  ++  G   G+               
Sbjct: 230  LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273

Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600
                + C  L  P  PF ACH  V+P PF   C  DLC +          C+ L+ YA  
Sbjct: 274  ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYARA 325

Query: 2601 CQEAGAALAGWRDR-----TLCES---------PCLQNPCQNDGQC--REQGATFTCECE 2644
            C +AG  L GWR +       C+           C    C     C   E      C C 
Sbjct: 326  CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP 385

Query: 2645 VG--YGGGLCMEPRDAP 2659
             G  +  G C+ P + P
Sbjct: 386  NGLIFEDGGCVAPAECP 402



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 105/477 (22%), Positives = 174/477 (36%), Gaps = 44/477 (9%)

Query: 569  KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
            +P V +   ++  E     +  PT   E+P +S E P  P+ +P + P+   T     P 
Sbjct: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452

Query: 628  ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
              TE+P +     + T+       +++ P  PTE P   ++  T S+       E  S+P
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510

Query: 686  TEKPSIPTEKPTISMEETIISTEKPT-ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744
                 +  + PT  M    + T + T I    P I     + P  +  +   K  T    
Sbjct: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLM-TKAVTVRGH 1564

Query: 745  PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804
             ++P     + P    +P+ +P  SP  +   +  PT       + T   T        P
Sbjct: 1565 GSLPVRTTPLQPSLTASPSSRPVASPGAI---SRSPTSSGSHKAVLTPAVTKVISRTGVP 1621

Query: 805  TEETTISTEKPSIPM-----EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859
                  S   PS P+         +P     T   E  +STEK      +P  S   P  
Sbjct: 1622 QPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ- 1680

Query: 860  PTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEK 919
            P   P+  P     P +  T+ T  P +P E  T +   L+  T+    +P     ST  
Sbjct: 1681 PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPFMSLESTRP 1734

Query: 920  PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979
              + +  P     +T++   K  + T  P  +P         P  S     +  +  T+P
Sbjct: 1735 SQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPLQPQATTLP 1780

Query: 980  TEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVILGTTT 1035
             +  T+    P  P     A  P H +P A G A  L++    P++ +  V  GT +
Sbjct: 1781 AQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTAS 1835



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)

Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
            CP G  +  CS    D    ++  R C + L         PC   C C +G +  G +C 
Sbjct: 811  CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868

Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
               +C CT     Y P  +     +TC     C   +    FQ T  P            
Sbjct: 869  LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908

Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
            C ++    C   G+ HY +FDG       AC + LVK                       
Sbjct: 909  CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946

Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
              +F +    ++ Y + +  +K   + + +  +     S  P           +   ++G
Sbjct: 947  --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004

Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
                       + + +D    + ++    + G++ G+CGNF+ +  +E+  P +    + 
Sbjct: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064

Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
             EF +SW   +    C   L            +P   C    LR   A+++C + L + V
Sbjct: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107

Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
            +  C   +D+T F  +C      C  GG  +  C ++ A+   C   G+    WR    C
Sbjct: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166

Query: 2208 PLECPAYS 2215
            P +C  ++
Sbjct: 1167 PYDCDFFN 1174



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)

Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
            QVT+ + +R +    Q   P +S+  G  ++ +    ++     +Q+++   + L+ +E 
Sbjct: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164

Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
              T   +  G+CG  + +  ++L +    V   A   + F++SW+     PS  + +   
Sbjct: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220

Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
            +  P          C      R    C   +  P  + C   I  T ++           
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267

Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
               Q  C AL  + A C    +    WR S +CP  C + S+Y  C+ +C P     DG 
Sbjct: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322

Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
              G   P  C    EGC+C  G +L       C+P ++C C D+ G    LG++W S  S
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382

Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
            GC +        I   D  CPS
Sbjct: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404



 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 109/470 (23%), Positives = 168/470 (35%), Gaps = 91/470 (19%)

Query: 647  PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
            P +    P  PT +      +    +E+ V P     +PTE     T  P+  +      
Sbjct: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414

Query: 707  TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756
               PT S E+P +  E P  PT +  ++P  P TT    P   TE+P +SP         
Sbjct: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471

Query: 757  -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804
                   + P  PTE P    ++   L IP   E  ++P    T PT        E T  
Sbjct: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530

Query: 805  T------EETTISTEKPSIP----MEKPTLPTEETTTSVEETTISTEKLTIPMEKP---- 850
            T         T+S+  P  P    M K        +  V  T +       P  +P    
Sbjct: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASP 1590

Query: 851  -TISTEKPTIPTEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEE 891
              IS    +  + K  ++P                 +  + P+  LT+  T    +P+  
Sbjct: 1591 GAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSP 1650

Query: 892  TTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKP 948
                + ++ + TEK      +P  S   P    +P+  P  P + TT++T    +P E P
Sbjct: 1651 LATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETP 1709

Query: 949  TISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLT 998
              +   L+  T+     P +S E  T P++ L+      ++P  K         P  K +
Sbjct: 1710 AAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKAS 1766

Query: 999  ALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
             +  P   P AT L A  +SP  P TP         T +   T   PP A
Sbjct: 1767 VITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 85/407 (20%), Positives = 143/407 (35%), Gaps = 70/407 (17%)

Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
            +P+   ++G  E     +       C P   ++E  CV      C +     +   +   
Sbjct: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007

Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
                  +C   G A++ G  RC     C                 +CS++ D  ++TFDG
Sbjct: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052

Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
                L     Y+L ++ D +   V  L  +  N      PP   + L     T   ++V 
Sbjct: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108

Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
            +      V  + +   P       R+   G    ++T  ++ + +      +I   S  S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168

Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
              +G   GLCG  D +  ND+ L  G++    ++   F +SW+V             P+ 
Sbjct: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213

Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
                G           ++CSP  ++ SN T            F+ACH+ V PE F E  +
Sbjct: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261

Query: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
             D    Q P       C  L+ Y  +C +    +  WR    C   C
Sbjct: 2262 RDTKYVQQP-------CVALTVYVAMCHKFHVCIE-WRRSDYCPFLC 2300



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)

Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
            C  +  Y  C  P   +C+   SP  +CG           C EGC C P          C
Sbjct: 707  CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765

Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
            +  + C+C +    Y PG          HC C  G
Sbjct: 766  VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  254 bits (649), Expect = 8e-67
 Identities = 298/1282 (23%), Positives = 471/1282 (36%), Gaps = 250/1282 (19%)

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
            +R +   +C P ++ S   C    +C  +HPA                  C C   N   
Sbjct: 97   ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 134

Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
             RCQ               +Y    +  + C A G  H  TFDG  ++  G  +Y L   
Sbjct: 135  PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180

Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
                 Q   F +   N+ + G    +  +AV +  V +  I L +  +V   G RV LP 
Sbjct: 181  HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 236

Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
             +   R  ++  +  V++       + +DG+  V + +     G   GLCGN N +  DD
Sbjct: 237  VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 294

Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
             +    KL  D ++   +W+    ++P         +P   Q+N  +M   + + C  L+
Sbjct: 295  LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 353

Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
             P  PF  CH  V P    ASC    C + GD    CR+L  YA  CAQAG+    WR +
Sbjct: 354  RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411

Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
               C + C   + +Y+ C + CP +C    +PR  C  + + C + C C  G I     C
Sbjct: 412  LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 467

Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
            V   +C C +  G+ +P G     +  C   CTC+      C  + C             
Sbjct: 468  VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 512

Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
                     C + G+ H+ +FDG  ++ P  C  +L K    + +   F ++ ++     
Sbjct: 513  ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 559

Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
              +   +  V + ++     QVTL +   VL+  +   +P  +       + SS++  V 
Sbjct: 560  NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 619

Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
              +GV+V +D   L L +++   +     G+CG FN   +D+ + P     ++   F NS
Sbjct: 620  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679

Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
            WK      +C  L+      P +             L+ A    +A   L   ++A C++
Sbjct: 680  WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 725

Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
             +   P+   C    C  G     LC  L  +   C+  GL          C L C A  
Sbjct: 726  FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 783

Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
             Y+ C+  C  +C DL        DG  + ++    C EGC C P   L    D CVPR+
Sbjct: 784  EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 841

Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
            QC                       CKD        A   + P G+ +V+          
Sbjct: 842  QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 901

Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
                                C   C C  G ++ GD       CP               
Sbjct: 902  SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 961

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            S  H  +    S    +   +  C+ YGD  Y TFDG  +   G     L+K+   +   
Sbjct: 962  SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 1021

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
            V   +VE  N      S +  ++ I+        +  G  L+V +     P  P   L  
Sbjct: 1022 V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 1066

Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
               V  W    + +  F    + + +  R    +     ++G ++GLCGN+D    N+M 
Sbjct: 1067 KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1126

Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
             P      N   FG+SW  V+  D L   PR +            LR      ECS    
Sbjct: 1127 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1173

Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAI 2599
                     +L++    F  CH  V    F  +C+ D C      +  E  C  +S YA 
Sbjct: 1174 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC-ECFCASVSAYAH 1221

Query: 2600 LCQEAGAALAGWRDRTLCESPC 2621
             C + G A+  WR   LC   C
Sbjct: 1222 QCCQHGVAV-DWRTPRLCPYDC 1242



 Score =  230 bits (586), Expect = 2e-59
 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)

Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
            C  +G  H  TFDG ++   GK +Y L    +P G S    F +   N+ Q G    +C 
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 206

Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
              V +  + E  + L K      GG +V LP +         +G +V ++ +    + WD
Sbjct: 207  RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 263

Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
            G   +Y+ +S    G   GLCGN + +  +D +   G    D  E  +SWQ         
Sbjct: 264  GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 323

Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
                 +  P C      +M G    C  L+    PF+ C  +V    F  SC  D+C   
Sbjct: 324  PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 381

Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
            G     C  ++     C  AG  ++ WR +   C + C   +  Y+ C   CP +CH   
Sbjct: 382  GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 441

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
            S +     CV+ C C  G +     C+  ++C C     L+P GS         K  C  
Sbjct: 442  SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 493

Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
             C C S        W C                A   A C+ +GD H+ TFDG  + F  
Sbjct: 494  TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 533

Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
            TC Y+L +   SRS  + F V+  N   G   + + +++V V +       ++L +   V
Sbjct: 534  TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 589

Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
            +L      +P +        RLSS  + + TN G++V YD   L + + V   +     G
Sbjct: 590  LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 649

Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
            LCG +N N+ DD L P           G +WK   +  P   LV G P   C  +  A +
Sbjct: 650  LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 706

Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
            ++ + C++L      F+ C   + P   F  C    C  +     LC +L  YA LC + 
Sbjct: 707  YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 762

Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
            G    +R R   C + C     YSPC +PC  TC  + +P  C            C E C
Sbjct: 763  GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 822

Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
             C     L   +  CVP  QC C      Y P
Sbjct: 823  ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 854



 Score =  179 bits (454), Expect = 3e-44
 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)

Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
            G  T  R  T  C   A  Y  C   CPASC  PR SC      C +GC C  G +F D 
Sbjct: 407  GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 465

Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
             C+  + C C ++   Y PG+        E C                    C   +G++
Sbjct: 466  GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 502

Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
             C      A C V GD H+ TFDGR + F   C YILA+   + T   F VT +N   G 
Sbjct: 503  ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 559

Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
             Q+G +C+  V V L   P   VTL +    L+  Q   +P        +   S  F+ +
Sbjct: 560  NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 618

Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
            +T  G+RV +D +  +LY+ V   +     GLCG ++GN+ +D L   G P    +  GN
Sbjct: 619  RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 678

Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
            SW+T       C    V  SP   CD  LQ++      C  L  T   F  C   +    
Sbjct: 679  SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 731

Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
            +F+ C  D C  +  Q  LC  ++     C+  G  V        C ++C  + +YS C 
Sbjct: 732  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789

Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
             PC  TC    S   C          D CVE C C P   L      C+PR+QC C
Sbjct: 790  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845



 Score =  168 bits (426), Expect = 6e-41
 Identities = 195/782 (24%), Positives = 295/782 (37%), Gaps = 156/782 (19%)

Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
            +C+  G+ H  +FDG  + +    +  LV    P      F I   H   + G+  +   
Sbjct: 150  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 206

Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
                  +  +  +     V     +V LP +  +    ++  + Y IV  +    + +DG
Sbjct: 207  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 264

Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
               + I++     G   G+CGN N + +D+L+  S ++ +   EFV+SW+++  +    P
Sbjct: 265  ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 324

Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
            +  SL       P   Q+NP        ++   E+CEA LR P  A C + +   PF   
Sbjct: 325  TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 372

Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
            C + LC+  G     C+AL  +   C   G     WR     C + C   + +Y  C+  
Sbjct: 373  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432

Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
            C  SC      C  +++  AC +GC C  G +  +  CV  ++C C + HG   P G S 
Sbjct: 433  CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 487

Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
            V   C   C CT G  +C    CP+                     +CSV GD  + TFD
Sbjct: 488  VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 525

Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
            G  Y       Y+L K         T+   P G+  +   V+  + +    PR  + L  
Sbjct: 526  GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 583

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
                        QAG  L+ +  K+  PY                 R N  +RV     G
Sbjct: 584  -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632

Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
             RLYL  D   V                      GLCG ++ N ++D + P G       
Sbjct: 633  LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 674

Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
             FGNSW+  +                   A   L +G  +  C    Q AS S QAC VL
Sbjct: 675  LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 715

Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610
                  FA C   ++P P+ E C  D C    P       C  L+ YA LC+  G  +  
Sbjct: 716  TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRHGLPV-D 767

Query: 2611 WRDR-----TLCE-----SPCLQNPCQNDGQCREQGATFTCECEVG--YGGGLCMEPRDA 2658
            +R R       CE     SPC+  PC     C++  +   C  + G       C+E    
Sbjct: 768  FRARLPACALSCEASKEYSPCVA-PCGR--TCQDLASPEACGVDGGDDLSRDECVEGCAC 824

Query: 2659 PP 2660
            PP
Sbjct: 825  PP 826



 Score =  150 bits (380), Expect = 1e-35
 Identities = 230/1054 (21%), Positives = 366/1054 (34%), Gaps = 231/1054 (21%)

Query: 598  PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
            PT +    T+P      PS+  PT   E+P +  E P  P+ +P +    P T +   P 
Sbjct: 1471 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524

Query: 656  VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
              TEEP      T T++++P+  T  + P+ PTE P+                     + 
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1584

Query: 693  TEKPTISMEETIISTEKPTI-------------SPEKPTIP--TEKPTI------PTEKS 731
             + PT  M    + T + T+             SP  P  P  T+  T+      P   +
Sbjct: 1585 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1644

Query: 732  TISPEKPTTPTEKPTIP----TEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKP 787
             + P    +P+ +P       +  PT S       T   T    +  +P          P
Sbjct: 1645 PLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSP 1704

Query: 788  TIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV----- 833
            + P T   T + + P +P      E  +STEK     S PM  P  P      S      
Sbjct: 1705 STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPA 1764

Query: 834  EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTEKL 878
            + TT++T    +P E P   ++ST             + T P++  +  P   ++P  K+
Sbjct: 1765 QHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKV 1824

Query: 879  ----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP---------- 920
                 + T  P   +  T +  +  T+P +  T+SP  P     ++   P          
Sbjct: 1825 GTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAG 1882

Query: 921  ---------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE-------- 960
                     T+PT    +P  E T S   +      T K  I  +++++PT         
Sbjct: 1883 TAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGG 1941

Query: 961  --KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP----H 1004
              + T +T  P  P             L +PT          T P + +  L P     H
Sbjct: 1942 PTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH 2001

Query: 1005 PSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASC 1059
             +     LAA         P   S P  S++ G      ++TE                 
Sbjct: 2002 GTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA---------------- 2045

Query: 1060 KSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRC 1119
             +   +C P+  + CV         + C++                 +    N ++HC  
Sbjct: 2046 -NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC-- 2078

Query: 1120 WPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCT 1179
             P         +CG   +     G   C  +     C ++ D  +VTFDG H     +  
Sbjct: 2079 -PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAI 2134

Query: 1180 YILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTLVG 1234
            YIL+Q    S D    V   + +    G       CL  + +T     VT+ +  R +  
Sbjct: 2135 YILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTV 2190

Query: 1235 GQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLCGN 1293
              Q   P +   G  +  +G    + T   ++++W      + V  S T   +  GLCG 
Sbjct: 2191 DLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGI 2250

Query: 1294 YDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSM 1349
             DG++ ND    DGS  G  E+     +SWQ         Q +++  +  + D S     
Sbjct: 2251 CDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP---- 2306

Query: 1350 SGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDA 1409
                 C R+V ++  F  C   V   SF +  + D    Q      C  ++     C   
Sbjct: 2307 -----CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCHKF 2356

Query: 1410 GHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACECNP 1464
             H    WR   +CP  C  +S Y  C   C  P TC  G  G    + C    E C C+ 
Sbjct: 2357 -HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSE 2415

Query: 1465 GFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
            G +L       CIP ++C C    G    +GE W
Sbjct: 2416 GTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449



 Score =  108 bits (269), Expect = 9e-23
 Identities = 103/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)

Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
            ACP    +  C+    D       TC      +  S R  C+  C C  G +  G  C  
Sbjct: 882  ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 941

Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
              +C C      YF  G++   P C   CVC+  +  +C    C                
Sbjct: 942  PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 981

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
               A+TCTA GD HY TFDG    F+G C   L +     + D  F V   N N      
Sbjct: 982  ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVN------ 1028

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRV---TIRLSSNLVLLYTNF 1652
              Y   +    F +SI++     V  +      P      +    T R+    ++ +   
Sbjct: 1029 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1086

Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
             + + +D    V V     + GQL GLCGN++  ++++   P+     +  + G++W   
Sbjct: 1087 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1146

Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
            + P++ +P           C  N + + +  K C+IL++    F  CH VV     +++C
Sbjct: 1147 ECPDTLDP--------RDMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNC 1196

Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
            +   CG    GD    C S+ AYA  C Q G A  WR    CP  C
Sbjct: 1197 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242



 Score =  107 bits (268), Expect = 1e-22
 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)

Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
            SR+    CP    + +C+             C     +   S    C  GC C  G L  
Sbjct: 876  SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 935

Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
             + C     C C +    Y PG +  SP                    C T  VCQ  + 
Sbjct: 936  GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 974

Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
            Q   HP A  +TC  YGD HY TFDG  F F+G C   L +   +++D  F V  +N   
Sbjct: 975  QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 1029

Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
               G+ C   + + +  S +          G           + V     G F  +   +
Sbjct: 1030 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085

Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
              + + WD    ++V     + G+L GLCGN+D  + N+    +     + +E G+SW  
Sbjct: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145

Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
             +  D    +   V +P  +   +        C  L+     FE C   V    F+ +C+
Sbjct: 1146 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1197

Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
             D CG    G     C  +S     C   G AV  WR P  CP  C
Sbjct: 1198 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)

Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
            A  C+   D  ++TFDG+         Y+L     S+S D    V   +     +  +++
Sbjct: 2108 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2162

Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
                              C VMLN     H+V +            PVW    R   R+ 
Sbjct: 2163 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2207

Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
             + ++ ++ T   +Q+++    G  +VE +  S   G   GLCG  + ++ +D    D  
Sbjct: 2208 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2265

Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
            + G   D      +W++P SS         +P SC     +      C  +++ +  FS 
Sbjct: 2266 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2318

Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
            CH+ VPP+S     +        DT  +   C +L  Y ++C +      WR   +CP  
Sbjct: 2319 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371

Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
            C   S+Y  C + C  P TC   I  P D        E C C +G IL       C+P  
Sbjct: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431

Query: 1866 QCGCTDPAGSYHPVGERW 1883
            +C CTD  G    +GE W
Sbjct: 2432 KCACTDSMGVPRALGETW 2449



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 86/377 (22%), Positives = 141/377 (37%), Gaps = 60/377 (15%)

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            +G  CQ+       N   ++   C  +G     TFDG  Y L G+ +Y L+   +  PEG
Sbjct: 133  TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 185

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
             +   ++  N      S       ++  +  + ++    E+     ++ +P+        
Sbjct: 186  -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 244

Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
             L G   Y++   +    +++ G     I +     G   GLCGN + + K+D++  SG 
Sbjct: 245  QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 301

Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
            LT ++  F +SW+ +  +          PR  P  ++  G   G+               
Sbjct: 302  LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 345

Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600
                + C  L  P  PF ACH  V+P PF   C  DLC +          C+ L+ YA  
Sbjct: 346  ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYARA 397

Query: 2601 CQEAGAALAGWRDR-----TLCES---------PCLQNPCQNDGQC--REQGATFTCECE 2644
            C +AG  L GWR +       C+           C    C     C   E      C C 
Sbjct: 398  CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP 457

Query: 2645 VG--YGGGLCMEPRDAP 2659
             G  +  G C+ P + P
Sbjct: 458  NGLIFEDGGCVAPAECP 474



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 105/477 (22%), Positives = 174/477 (36%), Gaps = 44/477 (9%)

Query: 569  KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
            +P V +   ++  E     +  PT   E+P +S E P  P+ +P + P+   T     P 
Sbjct: 1465 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524

Query: 628  ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
              TE+P +     + T+       +++ P  PTE P   ++  T S+       E  S+P
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1582

Query: 686  TEKPSIPTEKPTISMEETIISTEKPT-ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744
                 +  + PT  M    + T + T I    P I     + P  +  +   K  T    
Sbjct: 1583 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLM-TKAVTVRGH 1636

Query: 745  PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804
             ++P     + P    +P+ +P  SP  +   +  PT       + T   T        P
Sbjct: 1637 GSLPVRTTPLQPSLTASPSSRPVASPGAI---SRSPTSSGSHKAVLTPAVTKVISRTGVP 1693

Query: 805  TEETTISTEKPSIPM-----EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859
                  S   PS P+         +P     T   E  +STEK      +P  S   P  
Sbjct: 1694 QPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ- 1752

Query: 860  PTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEK 919
            P   P+  P     P +  T+ T  P +P E  T +   L+  T+    +P     ST  
Sbjct: 1753 PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPFMSLESTRP 1806

Query: 920  PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979
              + +  P     +T++   K  + T  P  +P         P  S     +  +  T+P
Sbjct: 1807 SQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPLQPQATTLP 1852

Query: 980  TEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVILGTTT 1035
             +  T+    P  P     A  P H +P A G A  L++    P++ +  V  GT +
Sbjct: 1853 AQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTAS 1907



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)

Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
            CP G  +  CS    D    ++  R C + L         PC   C C +G +  G +C 
Sbjct: 883  CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940

Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
               +C CT     Y P  +     +TC     C   +    FQ T  P            
Sbjct: 941  LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 980

Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
            C ++    C   G+ HY +FDG       AC + LVK                       
Sbjct: 981  CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 1018

Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
              +F +    ++ Y + +  +K   + + +  +     S  P           +   ++G
Sbjct: 1019 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076

Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
                       + + +D    + ++    + G++ G+CGNF+ +  +E+  P +    + 
Sbjct: 1077 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1136

Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
             EF +SW   +    C   L            +P   C    LR   A+++C + L + V
Sbjct: 1137 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1179

Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
            +  C   +D+T F  +C      C  GG  +  C ++ A+   C   G+    WR    C
Sbjct: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1238

Query: 2208 PLECPAYS 2215
            P +C  ++
Sbjct: 1239 PYDCDFFN 1246



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)

Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
            QVT+ + +R +    Q   P +S+  G  ++ +    ++     +Q+++   + L+ +E 
Sbjct: 2178 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2236

Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
              T   +  G+CG  + +  ++L +    V   A   + F++SW+     PS  + +   
Sbjct: 2237 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2292

Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
            +  P          C      R    C   +  P  + C   I  T ++           
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2339

Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
               Q  C AL  + A C    +    WR S +CP  C + S+Y  C+ +C P     DG 
Sbjct: 2340 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2394

Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
              G   P  C    EGC+C  G +L       C+P ++C C D+ G    LG++W S  S
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454

Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
            GC +        I   D  CPS
Sbjct: 2455 GCCQHQCQAPDTIVPVDLGCPS 2476



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 108/463 (23%), Positives = 166/463 (35%), Gaps = 91/463 (19%)

Query: 654  PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
            P  PT +      +    +E+ V P     +PTE     T  P+  +         PT S
Sbjct: 1442 PVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL---------PTPS 1490

Query: 714  PEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP---------------- 756
             E+P +  E P  PT +  ++P  P TT    P   TE+P +SP                
Sbjct: 1491 DEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTAS 1550

Query: 757  EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTPT------ 805
            + P  PTE P    ++   L IP   E  ++P    T PT        E T  T      
Sbjct: 1551 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRVTVIFAGS 1609

Query: 806  EETTISTEKPSIP----MEKPTLPTEETTTSVEETTISTEKLTIPMEKP-----TISTEK 856
               T+S+  P  P    M K        +  V  T +       P  +P      IS   
Sbjct: 1610 PNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSP 1669

Query: 857  PTIPTEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEETTISTEK 898
             +  + K  ++P                 +  + P+  LT+  T    +P+      + +
Sbjct: 1670 TSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLE 1729

Query: 899  LTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKL 955
            + + TEK      +P  S   P    +P+  P  P + TT++T    +P E P  +   L
Sbjct: 1730 IVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETPAAA--SL 1786

Query: 956  TIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLTALRPPHP 1005
            +  T+     P +S E  T P++ L+      ++P  K         P  K + +  P  
Sbjct: 1787 STATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTP-L 1844

Query: 1006 SPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
             P AT L A  +SP  P TP         T +   T   PP A
Sbjct: 1845 QPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1881



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 85/407 (20%), Positives = 143/407 (35%), Gaps = 70/407 (17%)

Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
            +P+   ++G  E     +       C P   ++E  CV      C +     +   +   
Sbjct: 2026 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2079

Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
                  +C   G A++ G  RC     C                 +CS++ D  ++TFDG
Sbjct: 2080 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2124

Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
                L     Y+L ++ D +   V  L  +  N      PP   + L     T   ++V 
Sbjct: 2125 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2180

Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
            +      V  + +   P       R+   G    ++T  ++ + +      +I   S  S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240

Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
              +G   GLCG  D +  ND+ L  G++    ++   F +SW+V             P+ 
Sbjct: 2241 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2285

Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
                G           ++CSP  ++ SN T            F+ACH+ V PE F E  +
Sbjct: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2333

Query: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
             D    Q P       C  L+ Y  +C +    +  WR    C   C
Sbjct: 2334 RDTKYVQQP-------CVALTVYVAMCHKFHVCIE-WRRSDYCPFLC 2372



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)

Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
            C  +  Y  C  P   +C+   SP  +CG           C EGC C P          C
Sbjct: 779  CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837

Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
            +  + C+C +    Y PG          HC C  G
Sbjct: 838  VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 870


>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  254 bits (649), Expect = 8e-67
 Identities = 298/1282 (23%), Positives = 471/1282 (36%), Gaps = 250/1282 (19%)

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
            +R +   +C P ++ S   C    +C  +HPA                  C C   N   
Sbjct: 25   ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62

Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
             RCQ               +Y    +  + C A G  H  TFDG  ++  G  +Y L   
Sbjct: 63   PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108

Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
                 Q   F +   N+ + G    +  +AV +  V +  I L +  +V   G RV LP 
Sbjct: 109  HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164

Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
             +   R  ++  +  V++       + +DG+  V + +     G   GLCGN N +  DD
Sbjct: 165  VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222

Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
             +    KL  D ++   +W+    ++P         +P   Q+N  +M   + + C  L+
Sbjct: 223  LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281

Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
             P  PF  CH  V P    ASC    C + GD    CR+L  YA  CAQAG+    WR +
Sbjct: 282  RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339

Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
               C + C   + +Y+ C + CP +C    +PR  C  + + C + C C  G I     C
Sbjct: 340  LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395

Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
            V   +C C +  G+ +P G     +  C   CTC+      C  + C             
Sbjct: 396  VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 440

Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
                     C + G+ H+ +FDG  ++ P  C  +L K    + +   F ++ ++     
Sbjct: 441  ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487

Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
              +   +  V + ++     QVTL +   VL+  +   +P  +       + SS++  V 
Sbjct: 488  NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547

Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
              +GV+V +D   L L +++   +     G+CG FN   +D+ + P     ++   F NS
Sbjct: 548  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607

Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
            WK      +C  L+      P +             L+ A    +A   L   ++A C++
Sbjct: 608  WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653

Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
             +   P+   C    C  G     LC  L  +   C+  GL          C L C A  
Sbjct: 654  FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711

Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
             Y+ C+  C  +C DL        DG  + ++    C EGC C P   L    D CVPR+
Sbjct: 712  EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769

Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
            QC                       CKD        A   + P G+ +V+          
Sbjct: 770  QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 829

Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
                                C   C C  G ++ GD       CP               
Sbjct: 830  SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 889

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            S  H  +    S    +   +  C+ YGD  Y TFDG  +   G     L+K+   +   
Sbjct: 890  SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 949

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
            V   +VE  N      S +  ++ I+        +  G  L+V +     P  P   L  
Sbjct: 950  V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 994

Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
               V  W    + +  F    + + +  R    +     ++G ++GLCGN+D    N+M 
Sbjct: 995  KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054

Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
             P      N   FG+SW  V+  D L   PR +            LR      ECS    
Sbjct: 1055 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1101

Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAI 2599
                     +L++    F  CH  V    F  +C+ D C      +  E  C  +S YA 
Sbjct: 1102 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC-ECFCASVSAYAH 1149

Query: 2600 LCQEAGAALAGWRDRTLCESPC 2621
             C + G A+  WR   LC   C
Sbjct: 1150 QCCQHGVAV-DWRTPRLCPYDC 1170



 Score =  230 bits (586), Expect = 2e-59
 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)

Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
            C  +G  H  TFDG ++   GK +Y L    +P G S    F +   N+ Q G    +C 
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134

Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
              V +  + E  + L K      GG +V LP +         +G +V ++ +    + WD
Sbjct: 135  RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191

Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
            G   +Y+ +S    G   GLCGN + +  +D +   G    D  E  +SWQ         
Sbjct: 192  GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251

Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
                 +  P C      +M G    C  L+    PF+ C  +V    F  SC  D+C   
Sbjct: 252  PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309

Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
            G     C  ++     C  AG  ++ WR +   C + C   +  Y+ C   CP +CH   
Sbjct: 310  GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
            S +     CV+ C C  G +     C+  ++C C     L+P GS         K  C  
Sbjct: 370  SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421

Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
             C C S        W C                A   A C+ +GD H+ TFDG  + F  
Sbjct: 422  TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461

Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
            TC Y+L +   SRS  + F V+  N   G   + + +++V V +       ++L +   V
Sbjct: 462  TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517

Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
            +L      +P +        RLSS  + + TN G++V YD   L + + V   +     G
Sbjct: 518  LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577

Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
            LCG +N N+ DD L P           G +WK   +  P   LV G P   C  +  A +
Sbjct: 578  LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634

Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
            ++ + C++L      F+ C   + P   F  C    C  +     LC +L  YA LC + 
Sbjct: 635  YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690

Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
            G    +R R   C + C     YSPC +PC  TC  + +P  C            C E C
Sbjct: 691  GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750

Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
             C     L   +  CVP  QC C      Y P
Sbjct: 751  ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782



 Score =  179 bits (454), Expect = 3e-44
 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)

Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
            G  T  R  T  C   A  Y  C   CPASC  PR SC      C +GC C  G +F D 
Sbjct: 335  GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393

Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
             C+  + C C ++   Y PG+        E C                    C   +G++
Sbjct: 394  GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430

Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
             C      A C V GD H+ TFDGR + F   C YILA+   + T   F VT +N   G 
Sbjct: 431  ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487

Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
             Q+G +C+  V V L   P   VTL +    L+  Q   +P        +   S  F+ +
Sbjct: 488  NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546

Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
            +T  G+RV +D +  +LY+ V   +     GLCG ++GN+ +D L   G P    +  GN
Sbjct: 547  RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606

Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
            SW+T       C    V  SP   CD  LQ++      C  L  T   F  C   +    
Sbjct: 607  SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659

Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
            +F+ C  D C  +  Q  LC  ++     C+  G  V        C ++C  + +YS C 
Sbjct: 660  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717

Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
             PC  TC    S   C          D CVE C C P   L      C+PR+QC C
Sbjct: 718  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773



 Score =  168 bits (426), Expect = 6e-41
 Identities = 195/782 (24%), Positives = 295/782 (37%), Gaps = 156/782 (19%)

Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
            +C+  G+ H  +FDG  + +    +  LV    P      F I   H   + G+  +   
Sbjct: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134

Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
                  +  +  +     V     +V LP +  +    ++  + Y IV  +    + +DG
Sbjct: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192

Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
               + I++     G   G+CGN N + +D+L+  S ++ +   EFV+SW+++  +    P
Sbjct: 193  ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252

Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
            +  SL       P   Q+NP        ++   E+CEA LR P  A C + +   PF   
Sbjct: 253  TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300

Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
            C + LC+  G     C+AL  +   C   G     WR     C + C   + +Y  C+  
Sbjct: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360

Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
            C  SC      C  +++  AC +GC C  G +  +  CV  ++C C + HG   P G S 
Sbjct: 361  CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415

Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
            V   C   C CT G  +C    CP+                     +CSV GD  + TFD
Sbjct: 416  VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453

Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
            G  Y       Y+L K         T+   P G+  +   V+  + +    PR  + L  
Sbjct: 454  GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
                        QAG  L+ +  K+  PY                 R N  +RV     G
Sbjct: 512  -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560

Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
             RLYL  D   V                      GLCG ++ N ++D + P G       
Sbjct: 561  LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602

Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
             FGNSW+  +                   A   L +G  +  C    Q AS S QAC VL
Sbjct: 603  LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643

Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610
                  FA C   ++P P+ E C  D C    P       C  L+ YA LC+  G  +  
Sbjct: 644  TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRHGLPV-D 695

Query: 2611 WRDR-----TLCE-----SPCLQNPCQNDGQCREQGATFTCECEVG--YGGGLCMEPRDA 2658
            +R R       CE     SPC+  PC     C++  +   C  + G       C+E    
Sbjct: 696  FRARLPACALSCEASKEYSPCVA-PCGR--TCQDLASPEACGVDGGDDLSRDECVEGCAC 752

Query: 2659 PP 2660
            PP
Sbjct: 753  PP 754



 Score =  152 bits (383), Expect = 6e-36
 Identities = 234/1056 (22%), Positives = 367/1056 (34%), Gaps = 235/1056 (22%)

Query: 598  PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
            PT +    T+P      PS+  PT   E+P +  E P  P+ +P +    P T +   P 
Sbjct: 1399 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452

Query: 656  VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
              TEEP      T T++++P+  T  + P+ PTE P+                     + 
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1512

Query: 693  TEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKPT 739
             + PT  M    + T + T+             SP  P  P     +        P + T
Sbjct: 1513 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1572

Query: 740  TPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPTE 785
             P    T  P+ +P  SP      PT         TP     IS   +  PT+  +    
Sbjct: 1573 PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--AS 1630

Query: 786  KPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV--- 833
             P+ P T   T + + P +P      E  +STEK     S PM  P  P      S    
Sbjct: 1631 SPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR 1690

Query: 834  --EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTE 876
              + TT++T    +P E P   ++ST             + T P++  +  P   ++P  
Sbjct: 1691 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1750

Query: 877  KL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP-------- 920
            K+     + T  P   +  T +  +  T+P +  T+SP  P     ++   P        
Sbjct: 1751 KVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPA 1808

Query: 921  -----------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE------ 960
                       T+PT    +P  E T S   +      T K  I  +++++PT       
Sbjct: 1809 AGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAE 1867

Query: 961  ----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP--- 1003
                + T +T  P  P             L +PT          T P + +  L P    
Sbjct: 1868 GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAE 1927

Query: 1004 -HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPA 1057
             H +     LAA         P   S P  S++ G      ++TE               
Sbjct: 1928 AHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA-------------- 1973

Query: 1058 SCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
               +   +C P+  + CV         + C++                 +    N ++HC
Sbjct: 1974 ---NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC 2006

Query: 1118 RCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGK 1177
               P         +CG   +     G   C  +     C ++ D  +VTFDG H     +
Sbjct: 2007 ---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKE 2060

Query: 1178 CTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTL 1232
              YIL+Q    S D    V   + +    G       CL  + +T     VT+ +  R +
Sbjct: 2061 AIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV 2116

Query: 1233 VGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLC 1291
                Q   P +   G  +  +G    + T   ++++W      + V  S T   +  GLC
Sbjct: 2117 TVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLC 2176

Query: 1292 GNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQS 1347
            G  DG++ ND    DGS  G  E+     +SWQ         Q +++  +  + D S   
Sbjct: 2177 GICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP-- 2234

Query: 1348 SMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQ 1407
                   C R+V ++  F  C   V   SF +  + D    Q      C  ++     C 
Sbjct: 2235 -------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCH 2282

Query: 1408 DAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACEC 1462
               H    WR   +CP  C  +S Y  C   C  P TC  G  G    + C    E C C
Sbjct: 2283 KF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVC 2341

Query: 1463 NPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
            + G +L       CIP ++C C    G    +GE W
Sbjct: 2342 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377



 Score =  108 bits (269), Expect = 9e-23
 Identities = 103/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)

Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
            ACP    +  C+    D       TC      +  S R  C+  C C  G +  G  C  
Sbjct: 810  ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869

Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
              +C C      YF  G++   P C   CVC+  +  +C    C                
Sbjct: 870  PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
               A+TCTA GD HY TFDG    F+G C   L +     + D  F V   N N      
Sbjct: 910  ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVN------ 956

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRV---TIRLSSNLVLLYTNF 1652
              Y   +    F +SI++     V  +      P      +    T R+    ++ +   
Sbjct: 957  -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014

Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
             + + +D    V V     + GQL GLCGN++  ++++   P+     +  + G++W   
Sbjct: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074

Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
            + P++ +P           C  N + + +  K C+IL++    F  CH VV     +++C
Sbjct: 1075 ECPDTLDP--------RDMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNC 1124

Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
            +   CG    GD    C S+ AYA  C Q G A  WR    CP  C
Sbjct: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170



 Score =  107 bits (268), Expect = 1e-22
 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)

Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
            SR+    CP    + +C+             C     +   S    C  GC C  G L  
Sbjct: 804  SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863

Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
             + C     C C +    Y PG +  SP                    C T  VCQ  + 
Sbjct: 864  GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902

Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
            Q   HP A  +TC  YGD HY TFDG  F F+G C   L +   +++D  F V  +N   
Sbjct: 903  QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957

Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
               G+ C   + + +  S +          G           + V     G F  +   +
Sbjct: 958  YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013

Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
              + + WD    ++V     + G+L GLCGN+D  + N+    +     + +E G+SW  
Sbjct: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073

Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
             +  D    +   V +P  +   +        C  L+     FE C   V    F+ +C+
Sbjct: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125

Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
             D CG    G     C  +S     C   G AV  WR P  CP  C
Sbjct: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)

Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
            A  C+   D  ++TFDG+         Y+L     S+S D    V   +     +  +++
Sbjct: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090

Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
                              C VMLN     H+V +            PVW    R   R+ 
Sbjct: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135

Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
             + ++ ++ T   +Q+++    G  +VE +  S   G   GLCG  + ++ +D    D  
Sbjct: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193

Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
            + G   D      +W++P SS         +P SC     +      C  +++ +  FS 
Sbjct: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246

Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
            CH+ VPP+S     +        DT  +   C +L  Y ++C +      WR   +CP  
Sbjct: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299

Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
            C   S+Y  C + C  P TC   I  P D        E C C +G IL       C+P  
Sbjct: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359

Query: 1866 QCGCTDPAGSYHPVGERW 1883
            +C CTD  G    +GE W
Sbjct: 2360 KCACTDSMGVPRALGETW 2377



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 86/377 (22%), Positives = 141/377 (37%), Gaps = 60/377 (15%)

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            +G  CQ+       N   ++   C  +G     TFDG  Y L G+ +Y L+   +  PEG
Sbjct: 61   TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
             +   ++  N      S       ++  +  + ++    E+     ++ +P+        
Sbjct: 114  -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172

Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
             L G   Y++   +    +++ G     I +     G   GLCGN + + K+D++  SG 
Sbjct: 173  QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229

Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
            LT ++  F +SW+ +  +          PR  P  ++  G   G+               
Sbjct: 230  LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273

Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600
                + C  L  P  PF ACH  V+P PF   C  DLC +          C+ L+ YA  
Sbjct: 274  ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYARA 325

Query: 2601 CQEAGAALAGWRDR-----TLCES---------PCLQNPCQNDGQC--REQGATFTCECE 2644
            C +AG  L GWR +       C+           C    C     C   E      C C 
Sbjct: 326  CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP 385

Query: 2645 VG--YGGGLCMEPRDAP 2659
             G  +  G C+ P + P
Sbjct: 386  NGLIFEDGGCVAPAECP 402



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)

Query: 569  KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
            +P V +   ++  E     +  PT   E+P +S E P  P+ +P + P+   T     P 
Sbjct: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452

Query: 628  ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
              TE+P +     + T+       +++ P  PTE P   ++  T S+       E  S+P
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510

Query: 686  TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
                 +  + PT  M    + T + T+             SP  P  P     +      
Sbjct: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1565

Query: 733  ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
              P + T P    T  P+ +P  S   P   +  PT S     + T   T    +  +P 
Sbjct: 1566 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1622

Query: 792  EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
                 S   P+TP      + E+         +P     T   E  +STEK      +P 
Sbjct: 1623 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1673

Query: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
             S   P  P   P+  P     P +  T+ T  P +P E  T +   L+  T+    +P 
Sbjct: 1674 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1726

Query: 912  KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
                ST    + +  P     +T++   K  + T  P  +P         P  S     +
Sbjct: 1727 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1772

Query: 972  PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
              +  T+P +  T+    P  P     A  P H +P A G A  L++    P++ +  V 
Sbjct: 1773 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1830

Query: 1031 LGTTT 1035
             GT +
Sbjct: 1831 EGTAS 1835



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)

Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
            CP G  +  CS    D    ++  R C + L         PC   C C +G +  G +C 
Sbjct: 811  CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868

Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
               +C CT     Y P  +     +TC     C   +    FQ T  P            
Sbjct: 869  LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908

Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
            C ++    C   G+ HY +FDG       AC + LVK                       
Sbjct: 909  CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946

Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
              +F +    ++ Y + +  +K   + + +  +     S  P           +   ++G
Sbjct: 947  --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004

Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
                       + + +D    + ++    + G++ G+CGNF+ +  +E+  P +    + 
Sbjct: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064

Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
             EF +SW   +    C   L            +P   C    LR   A+++C + L + V
Sbjct: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107

Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
            +  C   +D+T F  +C      C  GG  +  C ++ A+   C   G+    WR    C
Sbjct: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166

Query: 2208 PLECPAYS 2215
            P +C  ++
Sbjct: 1167 PYDCDFFN 1174



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)

Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
            QVT+ + +R +    Q   P +S+  G  ++ +    ++     +Q+++   + L+ +E 
Sbjct: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164

Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
              T   +  G+CG  + +  ++L +    V   A   + F++SW+     PS  + +   
Sbjct: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220

Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
            +  P          C      R    C   +  P  + C   I  T ++           
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267

Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
               Q  C AL  + A C    +    WR S +CP  C + S+Y  C+ +C P     DG 
Sbjct: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322

Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
              G   P  C    EGC+C  G +L       C+P ++C C D+ G    LG++W S  S
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382

Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
            GC +        I   D  CPS
Sbjct: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 109/472 (23%), Positives = 174/472 (36%), Gaps = 95/472 (20%)

Query: 647  PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
            P +    P  PT +      +    +E+ V P     +PTE     T  P+  +      
Sbjct: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414

Query: 707  TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756
               PT S E+P +  E P  PT +  ++P  P TT    P   TE+P +SP         
Sbjct: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471

Query: 757  -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804
                   + P  PTE P    ++   L IP   E  ++P    T PT        E T  
Sbjct: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530

Query: 805  T------EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPME 848
            T         T+S+  P  P  +  L T+  T          T+  + +++    + P+ 
Sbjct: 1531 TVIFAGSPNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVA 1588

Query: 849  KPTISTEKPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPI 889
             P   +  PT   + K  ++P                 +  + P+  LT+  T    +P+
Sbjct: 1589 SPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPV 1648

Query: 890  EETTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTE 946
                  + ++ + TEK      +P  S   P    +P+  P  P + TT++T    +P E
Sbjct: 1649 SPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPE 1707

Query: 947  KPTISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEK 996
             P  +   L+  T+     P +S E  T P++ L+      ++P  K         P  K
Sbjct: 1708 TPAAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPK 1764

Query: 997  LTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
             + +  P   P AT L A  +SP  P TP         T +   T   PP A
Sbjct: 1765 ASVITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 85/407 (20%), Positives = 143/407 (35%), Gaps = 70/407 (17%)

Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
            +P+   ++G  E     +       C P   ++E  CV      C +     +   +   
Sbjct: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007

Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
                  +C   G A++ G  RC     C                 +CS++ D  ++TFDG
Sbjct: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052

Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
                L     Y+L ++ D +   V  L  +  N      PP   + L     T   ++V 
Sbjct: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108

Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
            +      V  + +   P       R+   G    ++T  ++ + +      +I   S  S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168

Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
              +G   GLCG  D +  ND+ L  G++    ++   F +SW+V             P+ 
Sbjct: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213

Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
                G           ++CSP  ++ SN T            F+ACH+ V PE F E  +
Sbjct: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261

Query: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
             D    Q P       C  L+ Y  +C +    +  WR    C   C
Sbjct: 2262 RDTKYVQQP-------CVALTVYVAMCHKFHVCIE-WRRSDYCPFLC 2300



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)

Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
            C  +  Y  C  P   +C+   SP  +CG           C EGC C P          C
Sbjct: 707  CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765

Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
            +  + C+C +    Y PG          HC C  G
Sbjct: 766  VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798


>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  254 bits (649), Expect = 8e-67
 Identities = 298/1282 (23%), Positives = 471/1282 (36%), Gaps = 250/1282 (19%)

Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
            +R +   +C P ++ S   C    +C  +HPA                  C C   N   
Sbjct: 97   ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 134

Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
             RCQ               +Y    +  + C A G  H  TFDG  ++  G  +Y L   
Sbjct: 135  PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180

Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
                 Q   F +   N+ + G    +  +AV +  V +  I L +  +V   G RV LP 
Sbjct: 181  HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 236

Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
             +   R  ++  +  V++       + +DG+  V + +     G   GLCGN N +  DD
Sbjct: 237  VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 294

Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
             +    KL  D ++   +W+    ++P         +P   Q+N  +M   + + C  L+
Sbjct: 295  LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 353

Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
             P  PF  CH  V P    ASC    C + GD    CR+L  YA  CAQAG+    WR +
Sbjct: 354  RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411

Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
               C + C   + +Y+ C + CP +C    +PR  C  + + C + C C  G I     C
Sbjct: 412  LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 467

Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
            V   +C C +  G+ +P G     +  C   CTC+      C  + C             
Sbjct: 468  VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 512

Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
                     C + G+ H+ +FDG  ++ P  C  +L K    + +   F ++ ++     
Sbjct: 513  ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 559

Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
              +   +  V + ++     QVTL +   VL+  +   +P  +       + SS++  V 
Sbjct: 560  NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 619

Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
              +GV+V +D   L L +++   +     G+CG FN   +D+ + P     ++   F NS
Sbjct: 620  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679

Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
            WK      +C  L+      P +             L+ A    +A   L   ++A C++
Sbjct: 680  WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 725

Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
             +   P+   C    C  G     LC  L  +   C+  GL          C L C A  
Sbjct: 726  FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 783

Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
             Y+ C+  C  +C DL        DG  + ++    C EGC C P   L    D CVPR+
Sbjct: 784  EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 841

Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
            QC                       CKD        A   + P G+ +V+          
Sbjct: 842  QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 901

Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
                                C   C C  G ++ GD       CP               
Sbjct: 902  SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 961

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            S  H  +    S    +   +  C+ YGD  Y TFDG  +   G     L+K+   +   
Sbjct: 962  SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 1021

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
            V   +VE  N      S +  ++ I+        +  G  L+V +     P  P   L  
Sbjct: 1022 V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 1066

Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
               V  W    + +  F    + + +  R    +     ++G ++GLCGN+D    N+M 
Sbjct: 1067 KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1126

Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
             P      N   FG+SW  V+  D L   PR +            LR      ECS    
Sbjct: 1127 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1173

Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAI 2599
                     +L++    F  CH  V    F  +C+ D C      +  E  C  +S YA 
Sbjct: 1174 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC-ECFCASVSAYAH 1221

Query: 2600 LCQEAGAALAGWRDRTLCESPC 2621
             C + G A+  WR   LC   C
Sbjct: 1222 QCCQHGVAV-DWRTPRLCPYDC 1242



 Score =  230 bits (586), Expect = 2e-59
 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)

Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
            C  +G  H  TFDG ++   GK +Y L    +P G S    F +   N+ Q G    +C 
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 206

Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
              V +  + E  + L K      GG +V LP +         +G +V ++ +    + WD
Sbjct: 207  RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 263

Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
            G   +Y+ +S    G   GLCGN + +  +D +   G    D  E  +SWQ         
Sbjct: 264  GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 323

Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
                 +  P C      +M G    C  L+    PF+ C  +V    F  SC  D+C   
Sbjct: 324  PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 381

Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
            G     C  ++     C  AG  ++ WR +   C + C   +  Y+ C   CP +CH   
Sbjct: 382  GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 441

Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
            S +     CV+ C C  G +     C+  ++C C     L+P GS         K  C  
Sbjct: 442  SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 493

Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
             C C S        W C                A   A C+ +GD H+ TFDG  + F  
Sbjct: 494  TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 533

Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
            TC Y+L +   SRS  + F V+  N   G   + + +++V V +       ++L +   V
Sbjct: 534  TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 589

Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
            +L      +P +        RLSS  + + TN G++V YD   L + + V   +     G
Sbjct: 590  LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 649

Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
            LCG +N N+ DD L P           G +WK   +  P   LV G P   C  +  A +
Sbjct: 650  LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 706

Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
            ++ + C++L      F+ C   + P   F  C    C  +     LC +L  YA LC + 
Sbjct: 707  YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 762

Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
            G    +R R   C + C     YSPC +PC  TC  + +P  C            C E C
Sbjct: 763  GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 822

Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
             C     L   +  CVP  QC C      Y P
Sbjct: 823  ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 854



 Score =  179 bits (454), Expect = 3e-44
 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)

Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
            G  T  R  T  C   A  Y  C   CPASC  PR SC      C +GC C  G +F D 
Sbjct: 407  GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 465

Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
             C+  + C C ++   Y PG+        E C                    C   +G++
Sbjct: 466  GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 502

Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
             C      A C V GD H+ TFDGR + F   C YILA+   + T   F VT +N   G 
Sbjct: 503  ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 559

Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
             Q+G +C+  V V L   P   VTL +    L+  Q   +P        +   S  F+ +
Sbjct: 560  NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 618

Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
            +T  G+RV +D +  +LY+ V   +     GLCG ++GN+ +D L   G P    +  GN
Sbjct: 619  RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 678

Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
            SW+T       C    V  SP   CD  LQ++      C  L  T   F  C   +    
Sbjct: 679  SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 731

Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
            +F+ C  D C  +  Q  LC  ++     C+  G  V        C ++C  + +YS C 
Sbjct: 732  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789

Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
             PC  TC    S   C          D CVE C C P   L      C+PR+QC C
Sbjct: 790  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845



 Score =  168 bits (426), Expect = 6e-41
 Identities = 195/782 (24%), Positives = 295/782 (37%), Gaps = 156/782 (19%)

Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
            +C+  G+ H  +FDG  + +    +  LV    P      F I   H   + G+  +   
Sbjct: 150  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 206

Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
                  +  +  +     V     +V LP +  +    ++  + Y IV  +    + +DG
Sbjct: 207  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 264

Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
               + I++     G   G+CGN N + +D+L+  S ++ +   EFV+SW+++  +    P
Sbjct: 265  ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 324

Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
            +  SL       P   Q+NP        ++   E+CEA LR P  A C + +   PF   
Sbjct: 325  TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 372

Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
            C + LC+  G     C+AL  +   C   G     WR     C + C   + +Y  C+  
Sbjct: 373  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432

Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
            C  SC      C  +++  AC +GC C  G +  +  CV  ++C C + HG   P G S 
Sbjct: 433  CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 487

Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
            V   C   C CT G  +C    CP+                     +CSV GD  + TFD
Sbjct: 488  VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 525

Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
            G  Y       Y+L K         T+   P G+  +   V+  + +    PR  + L  
Sbjct: 526  GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 583

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
                        QAG  L+ +  K+  PY                 R N  +RV     G
Sbjct: 584  -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632

Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
             RLYL  D   V                      GLCG ++ N ++D + P G       
Sbjct: 633  LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 674

Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
             FGNSW+  +                   A   L +G  +  C    Q AS S QAC VL
Sbjct: 675  LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 715

Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610
                  FA C   ++P P+ E C  D C    P       C  L+ YA LC+  G  +  
Sbjct: 716  TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRHGLPV-D 767

Query: 2611 WRDR-----TLCE-----SPCLQNPCQNDGQCREQGATFTCECEVG--YGGGLCMEPRDA 2658
            +R R       CE     SPC+  PC     C++  +   C  + G       C+E    
Sbjct: 768  FRARLPACALSCEASKEYSPCVA-PCGR--TCQDLASPEACGVDGGDDLSRDECVEGCAC 824

Query: 2659 PP 2660
            PP
Sbjct: 825  PP 826



 Score =  152 bits (383), Expect = 6e-36
 Identities = 234/1056 (22%), Positives = 367/1056 (34%), Gaps = 235/1056 (22%)

Query: 598  PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
            PT +    T+P      PS+  PT   E+P +  E P  P+ +P +    P T +   P 
Sbjct: 1471 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524

Query: 656  VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
              TEEP      T T++++P+  T  + P+ PTE P+                     + 
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1584

Query: 693  TEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKPT 739
             + PT  M    + T + T+             SP  P  P     +        P + T
Sbjct: 1585 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1644

Query: 740  TPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPTE 785
             P    T  P+ +P  SP      PT         TP     IS   +  PT+  +    
Sbjct: 1645 PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--AS 1702

Query: 786  KPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV--- 833
             P+ P T   T + + P +P      E  +STEK     S PM  P  P      S    
Sbjct: 1703 SPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR 1762

Query: 834  --EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTE 876
              + TT++T    +P E P   ++ST             + T P++  +  P   ++P  
Sbjct: 1763 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1822

Query: 877  KL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP-------- 920
            K+     + T  P   +  T +  +  T+P +  T+SP  P     ++   P        
Sbjct: 1823 KVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPA 1880

Query: 921  -----------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE------ 960
                       T+PT    +P  E T S   +      T K  I  +++++PT       
Sbjct: 1881 AGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAE 1939

Query: 961  ----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP--- 1003
                + T +T  P  P             L +PT          T P + +  L P    
Sbjct: 1940 GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAE 1999

Query: 1004 -HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPA 1057
             H +     LAA         P   S P  S++ G      ++TE               
Sbjct: 2000 AHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA-------------- 2045

Query: 1058 SCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
               +   +C P+  + CV         + C++                 +    N ++HC
Sbjct: 2046 ---NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC 2078

Query: 1118 RCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGK 1177
               P         +CG   +     G   C  +     C ++ D  +VTFDG H     +
Sbjct: 2079 ---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKE 2132

Query: 1178 CTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTL 1232
              YIL+Q    S D    V   + +    G       CL  + +T     VT+ +  R +
Sbjct: 2133 AIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV 2188

Query: 1233 VGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLC 1291
                Q   P +   G  +  +G    + T   ++++W      + V  S T   +  GLC
Sbjct: 2189 TVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLC 2248

Query: 1292 GNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQS 1347
            G  DG++ ND    DGS  G  E+     +SWQ         Q +++  +  + D S   
Sbjct: 2249 GICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP-- 2306

Query: 1348 SMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQ 1407
                   C R+V ++  F  C   V   SF +  + D    Q      C  ++     C 
Sbjct: 2307 -------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCH 2354

Query: 1408 DAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACEC 1462
               H    WR   +CP  C  +S Y  C   C  P TC  G  G    + C    E C C
Sbjct: 2355 KF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVC 2413

Query: 1463 NPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
            + G +L       CIP ++C C    G    +GE W
Sbjct: 2414 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449



 Score =  108 bits (269), Expect = 9e-23
 Identities = 103/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)

Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
            ACP    +  C+    D       TC      +  S R  C+  C C  G +  G  C  
Sbjct: 882  ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 941

Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
              +C C      YF  G++   P C   CVC+  +  +C    C                
Sbjct: 942  PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 981

Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
               A+TCTA GD HY TFDG    F+G C   L +     + D  F V   N N      
Sbjct: 982  ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVN------ 1028

Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRV---TIRLSSNLVLLYTNF 1652
              Y   +    F +SI++     V  +      P      +    T R+    ++ +   
Sbjct: 1029 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1086

Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
             + + +D    V V     + GQL GLCGN++  ++++   P+     +  + G++W   
Sbjct: 1087 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1146

Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
            + P++ +P           C  N + + +  K C+IL++    F  CH VV     +++C
Sbjct: 1147 ECPDTLDP--------RDMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNC 1196

Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
            +   CG    GD    C S+ AYA  C Q G A  WR    CP  C
Sbjct: 1197 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242



 Score =  107 bits (268), Expect = 1e-22
 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)

Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
            SR+    CP    + +C+             C     +   S    C  GC C  G L  
Sbjct: 876  SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 935

Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
             + C     C C +    Y PG +  SP                    C T  VCQ  + 
Sbjct: 936  GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 974

Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
            Q   HP A  +TC  YGD HY TFDG  F F+G C   L +   +++D  F V  +N   
Sbjct: 975  QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 1029

Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
               G+ C   + + +  S +          G           + V     G F  +   +
Sbjct: 1030 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085

Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
              + + WD    ++V     + G+L GLCGN+D  + N+    +     + +E G+SW  
Sbjct: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145

Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
             +  D    +   V +P  +   +        C  L+     FE C   V    F+ +C+
Sbjct: 1146 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1197

Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
             D CG    G     C  +S     C   G AV  WR P  CP  C
Sbjct: 1198 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)

Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
            A  C+   D  ++TFDG+         Y+L     S+S D    V   +     +  +++
Sbjct: 2108 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2162

Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
                              C VMLN     H+V +            PVW    R   R+ 
Sbjct: 2163 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2207

Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
             + ++ ++ T   +Q+++    G  +VE +  S   G   GLCG  + ++ +D    D  
Sbjct: 2208 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2265

Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
            + G   D      +W++P SS         +P SC     +      C  +++ +  FS 
Sbjct: 2266 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2318

Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
            CH+ VPP+S     +        DT  +   C +L  Y ++C +      WR   +CP  
Sbjct: 2319 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371

Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
            C   S+Y  C + C  P TC   I  P D        E C C +G IL       C+P  
Sbjct: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431

Query: 1866 QCGCTDPAGSYHPVGERW 1883
            +C CTD  G    +GE W
Sbjct: 2432 KCACTDSMGVPRALGETW 2449



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 86/377 (22%), Positives = 141/377 (37%), Gaps = 60/377 (15%)

Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
            +G  CQ+       N   ++   C  +G     TFDG  Y L G+ +Y L+   +  PEG
Sbjct: 133  TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 185

Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
             +   ++  N      S       ++  +  + ++    E+     ++ +P+        
Sbjct: 186  -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 244

Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
             L G   Y++   +    +++ G     I +     G   GLCGN + + K+D++  SG 
Sbjct: 245  QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 301

Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
            LT ++  F +SW+ +  +          PR  P  ++  G   G+               
Sbjct: 302  LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 345

Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600
                + C  L  P  PF ACH  V+P PF   C  DLC +          C+ L+ YA  
Sbjct: 346  ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYARA 397

Query: 2601 CQEAGAALAGWRDR-----TLCES---------PCLQNPCQNDGQC--REQGATFTCECE 2644
            C +AG  L GWR +       C+           C    C     C   E      C C 
Sbjct: 398  CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP 457

Query: 2645 VG--YGGGLCMEPRDAP 2659
             G  +  G C+ P + P
Sbjct: 458  NGLIFEDGGCVAPAECP 474



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)

Query: 569  KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
            +P V +   ++  E     +  PT   E+P +S E P  P+ +P + P+   T     P 
Sbjct: 1465 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524

Query: 628  ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
              TE+P +     + T+       +++ P  PTE P   ++  T S+       E  S+P
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1582

Query: 686  TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
                 +  + PT  M    + T + T+             SP  P  P     +      
Sbjct: 1583 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1637

Query: 733  ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
              P + T P    T  P+ +P  S   P   +  PT S     + T   T    +  +P 
Sbjct: 1638 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1694

Query: 792  EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
                 S   P+TP      + E+         +P     T   E  +STEK      +P 
Sbjct: 1695 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1745

Query: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
             S   P  P   P+  P     P +  T+ T  P +P E  T +   L+  T+    +P 
Sbjct: 1746 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1798

Query: 912  KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
                ST    + +  P     +T++   K  + T  P  +P         P  S     +
Sbjct: 1799 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1844

Query: 972  PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
              +  T+P +  T+    P  P     A  P H +P A G A  L++    P++ +  V 
Sbjct: 1845 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1902

Query: 1031 LGTTT 1035
             GT +
Sbjct: 1903 EGTAS 1907



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)

Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
            CP G  +  CS    D    ++  R C + L         PC   C C +G +  G +C 
Sbjct: 883  CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940

Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
               +C CT     Y P  +     +TC     C   +    FQ T  P            
Sbjct: 941  LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 980

Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
            C ++    C   G+ HY +FDG       AC + LVK                       
Sbjct: 981  CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 1018

Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
              +F +    ++ Y + +  +K   + + +  +     S  P           +   ++G
Sbjct: 1019 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076

Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
                       + + +D    + ++    + G++ G+CGNF+ +  +E+  P +    + 
Sbjct: 1077 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1136

Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
             EF +SW   +    C   L            +P   C    LR   A+++C + L + V
Sbjct: 1137 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1179

Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
            +  C   +D+T F  +C      C  GG  +  C ++ A+   C   G+    WR    C
Sbjct: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1238

Query: 2208 PLECPAYS 2215
            P +C  ++
Sbjct: 1239 PYDCDFFN 1246



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)

Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
            QVT+ + +R +    Q   P +S+  G  ++ +    ++     +Q+++   + L+ +E 
Sbjct: 2178 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2236

Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
              T   +  G+CG  + +  ++L +    V   A   + F++SW+     PS  + +   
Sbjct: 2237 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2292

Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
            +  P          C      R    C   +  P  + C   I  T ++           
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2339

Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
               Q  C AL  + A C    +    WR S +CP  C + S+Y  C+ +C P     DG 
Sbjct: 2340 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2394

Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
              G   P  C    EGC+C  G +L       C+P ++C C D+ G    LG++W S  S
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454

Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
            GC +        I   D  CPS
Sbjct: 2455 GCCQHQCQAPDTIVPVDLGCPS 2476



 Score = 74.3 bits (181), Expect = 2e-12
 Identities = 108/465 (23%), Positives = 172/465 (36%), Gaps = 95/465 (20%)

Query: 654  PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
            P  PT +      +    +E+ V P     +PTE     T  P+  +         PT S
Sbjct: 1442 PVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL---------PTPS 1490

Query: 714  PEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP---------------- 756
             E+P +  E P  PT +  ++P  P TT    P   TE+P +SP                
Sbjct: 1491 DEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTAS 1550

Query: 757  EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTPT------ 805
            + P  PTE P    ++   L IP   E  ++P    T PT        E T  T      
Sbjct: 1551 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRVTVIFAGS 1609

Query: 806  EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPMEKPTISTE 855
               T+S+  P  P  +  L T+  T          T+  + +++    + P+  P   + 
Sbjct: 1610 PNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISR 1667

Query: 856  KPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEETTIST 896
             PT   + K  ++P                 +  + P+  LT+  T    +P+      +
Sbjct: 1668 SPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1727

Query: 897  EKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
             ++ + TEK      +P  S   P    +P+  P  P + TT++T    +P E P  +  
Sbjct: 1728 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETPAAA-- 1784

Query: 954  KLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLTALRPP 1003
             L+  T+     P +S E  T P++ L+      ++P  K         P  K + +  P
Sbjct: 1785 SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTP 1843

Query: 1004 HPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
               P AT L A  +SP  P TP         T +   T   PP A
Sbjct: 1844 -LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1881



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 85/407 (20%), Positives = 143/407 (35%), Gaps = 70/407 (17%)

Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
            +P+   ++G  E     +       C P   ++E  CV      C +     +   +   
Sbjct: 2026 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2079

Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
                  +C   G A++ G  RC     C                 +CS++ D  ++TFDG
Sbjct: 2080 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2124

Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
                L     Y+L ++ D +   V  L  +  N      PP   + L     T   ++V 
Sbjct: 2125 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2180

Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
            +      V  + +   P       R+   G    ++T  ++ + +      +I   S  S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240

Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
              +G   GLCG  D +  ND+ L  G++    ++   F +SW+V             P+ 
Sbjct: 2241 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2285

Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
                G           ++CSP  ++ SN T            F+ACH+ V PE F E  +
Sbjct: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2333

Query: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
             D    Q P       C  L+ Y  +C +    +  WR    C   C
Sbjct: 2334 RDTKYVQQP-------CVALTVYVAMCHKFHVCIE-WRRSDYCPFLC 2372



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)

Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
            C  +  Y  C  P   +C+   SP  +CG           C EGC C P          C
Sbjct: 779  CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837

Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
            +  + C+C +    Y PG          HC C  G
Sbjct: 838  VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 870


>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
          Length = 1503

 Score =  231 bits (589), Expect = 7e-60
 Identities = 165/500 (33%), Positives = 226/500 (45%), Gaps = 71/500 (14%)

Query: 1422 CP--MACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEA----------CECNPGFVLS 1469
            CP  + CPP+       + C  TC    S   CS+  + +          C+C     L 
Sbjct: 996  CPSLVGCPPSQLLPPGPQHCCPTCAEALSN--CSEGLLGSELAPPDPCYTCQCQDLTWLC 1053

Query: 1470 GLECIPRSQC---------------------GCLHPAGSYFKVGERWYKPGCKELCVCES 1508
              +  P   C                      C+H  G     GERW    C   C C +
Sbjct: 1054 IHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQ-GREVASGERWTVDTCTS-CSCMA 1111

Query: 1509 NNRIRCQPWRCRAQEFCGQQDGIY----GCHAQ---GAATCTASGDPHYLTFDGALHHFM 1561
               +RCQ  RC     CG           C  +     A+C A GDPHY TFDG L HF 
Sbjct: 1112 GT-VRCQSQRCSPLS-CGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQ 1169

Query: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVML 1621
            G+C+YVL + C S      F V  TN++RG    V++ + V V + D+++ LL+   V +
Sbjct: 1170 GSCSYVLAKDCHSGD----FSVHVTNDDRGRS-GVAWTQEVAVLLGDMAVRLLQDGAVTV 1224

Query: 1622 NGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCG 1681
            +GH VALP +L +  + + L  + V+L+   GLQV +DG   VEV+VP SY G+ CGLCG
Sbjct: 1225 DGHPVALP-FLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCG 1283

Query: 1682 NYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGK---PSSCQENSMADAW 1738
            N+N  + DD   P+  L       G +W++ E   PG     G+   P            
Sbjct: 1284 NFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREA 1343

Query: 1739 NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC----GTKGDTTALCRSLQAYASLCA 1794
            N  C +L     PFS+CH VVPP+  FA+CV+  C    G+  D   LC +L+AYAS C 
Sbjct: 1344 NARCGVL--KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSAD-ACLCDALEAYASHCR 1400

Query: 1795 QAGQAPAWRNRTFCPMRCP--PGSSYSPCSSPCPDTCSSINNP-----RDCPKALPCAES 1847
            QAG  P WR  T C + CP   G  +  C  PCP TC + + P       C +  PC   
Sbjct: 1401 QAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVR--PCVPG 1458

Query: 1848 CECQKGHILSGTSCVPLGQC 1867
            C+C  G +     C+P   C
Sbjct: 1459 CQCPAGLVEHEAHCIPPEAC 1478



 Score =  197 bits (502), Expect = 9e-50
 Identities = 144/509 (28%), Positives = 210/509 (41%), Gaps = 63/509 (12%)

Query: 1007 PTATGLAALVMSPHAPS--TPMTSVILGTTTTSRSSTERCPPNARY-------------E 1051
            P+  G     + P  P    P  +  L   +     +E  PP+  Y             +
Sbjct: 997  PSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQ 1056

Query: 1052 SC---ACPASCK-SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE 1107
            +C   +CP S + +P  SC P+CR                  A + +C +       G  
Sbjct: 1057 ACPELSCPLSERHTPPGSCCPVCR------------------APTQSCVHQGREVASGER 1098

Query: 1108 WFSPNCTEHCRCWPGSRVECQISQC-----GTHTVCQLKNGQYGCHPYAGTATCLVYGDP 1162
            W    CT  C C  G+ V CQ  +C     G      L  G          A+C+ +GDP
Sbjct: 1099 WTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDP 1156

Query: 1163 HYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPEST 1222
            HY TFDGR   F G C+Y+LA+ C +     F V   N+++G+ GV+   +V V L +  
Sbjct: 1157 HYRTFDGRLLHFQGSCSYVLAKDCHSGD---FSVHVTNDDRGRSGVAWTQEVAVLLGDMA 1213

Query: 1223 VTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSST 1282
            V LL+     V G  V LP +    +++   G  V L  + GL+V WDG  Q+ V+V  +
Sbjct: 1214 VRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGS 1273

Query: 1283 YSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD--EDQECQKYQVVNSPS 1340
            Y G+ CGLCGN++G + +D    +G     +   GNSWQ  +     + C   + V+ P 
Sbjct: 1274 YQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PC 1332

Query: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF---QGLQHLLCT 1397
              +  ++       CG L  +  PF  C   V    FF +C+ D+C           LC 
Sbjct: 1333 RAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCD 1390

Query: 1398 HMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSL--CAKPCPDTCHS-----GFSGM 1450
             +    + C+ AG     WR P  C + CP    +    C  PCP TC +     G    
Sbjct: 1391 ALEAYASHCRQAG-VTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAA 1449

Query: 1451 FCSDRCVEACECNPGFVLSGLECIPRSQC 1479
             C   CV  C+C  G V     CIP   C
Sbjct: 1450 HCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478



 Score =  159 bits (401), Expect = 5e-38
 Identities = 167/624 (26%), Positives = 251/624 (40%), Gaps = 101/624 (16%)

Query: 1700 GDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINP-QGPFSQCHQV 1758
            G+    G+ W  P+S+   C         C E  +  A  +  +    P QGP   C   
Sbjct: 900  GEEHPEGSRWVPPDSACSSCV--------CHEGVVTCARIQCISSCAQPRQGPHDCC--- 948

Query: 1759 VPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCA------QAGQAPAWR-NRTFCP-- 1809
              PQ S        C  +G       S Q  A  C       Q    P+ R +R  CP  
Sbjct: 949  --PQCS-------DCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSL 999

Query: 1810 MRCPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTS 1860
            + CPP     P    C  TC+   +  +C + L         PC  +C+CQ    L    
Sbjct: 1000 VGCPPSQLLPPGPQHCCPTCAEALS--NCSEGLLGSELAPPDPCY-TCQCQDLTWLCIHQ 1056

Query: 1861 CVPLGQCGCTD---PAGSYHPV-----------------GERWYTENTCTRLCTCSVHN- 1899
              P   C  ++   P GS  PV                 GERW T +TCT  C+C     
Sbjct: 1057 ACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERW-TVDTCTS-CSCMAGTV 1114

Query: 1900 ---NITCFQSTCKPNQICWALDGLL--RCRASGVGVCQLPGESHYVSFDGSNHSIPDACT 1954
               +  C   +C P++      G    RC       C   G+ HY +FDG       +C+
Sbjct: 1115 RCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CMAFGDPHYRTFDGRLLHFQGSCS 1173

Query: 1955 LVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQ 2014
             VL K CH       F +   ++ + G +      EV + + D  V L +   V ++   
Sbjct: 1174 YVLAKDCHSGD----FSVHVTND-DRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHP 1228

Query: 2015 VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFND 2074
            V LP + + P + V+      I++ + G+QV +DG   +E+ +P +Y G+ CG+CGNFN 
Sbjct: 1229 VALPFLQE-PLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNG 1287

Query: 2075 EEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADL 2134
              +D+L  P   +  S++ F NSW+           L   +   A ++ +P   CRAA  
Sbjct: 1288 FAQDDLQGPEGLLLPSEAAFGNSWQ-------VSEGLWPGRPCSAGREVDP---CRAAGY 1337

Query: 2135 RRARE---KCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQA---LCQALQAFG 2188
            R  RE   +C   L++  +++C + +   PF   C   LC  G    A   LC AL+A+ 
Sbjct: 1338 RARREANARC-GVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYA 1396

Query: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYT--NCLPSCSPSCWDLD---GRCEGAKVPSA 2243
            + C+  G+  P WR  + C + CP    +    C P C  +C++     G    A     
Sbjct: 1397 SHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGEL-AAHCVRP 1454

Query: 2244 CAEGCICQPGYVLSEDKCVPRSQC 2267
            C  GC C  G V  E  C+P   C
Sbjct: 1455 CVPGCQCPAGLVEHEAHCIPPEAC 1478



 Score =  142 bits (357), Expect = 6e-33
 Identities = 124/466 (26%), Positives = 171/466 (36%), Gaps = 61/466 (13%)

Query: 2191 CQSQGLKPPLWR-NSSFCP--LECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
            C+ Q   PP  R +   CP  + CP           C P+C +    C    + S  A  
Sbjct: 979  CEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPP 1038

Query: 2248 -----CICQPGYVLSEDKCVPRSQCGCKDAH--------------------GGSIPLGKS 2282
                 C CQ    L   +  P   C   + H                    G  +  G+ 
Sbjct: 1039 DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098

Query: 2283 WVSSGCTEKCVCTGGAIQCGDFRCPSGSHC------QLTSDNSNSNCVSDKSEQCSVYGD 2336
            W    CT  C C  G ++C   RC S   C       L+  +    C+  +   C  +GD
Sbjct: 1099 WTVDTCTS-CSCMAGTVRCQSQRC-SPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGD 1155

Query: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI-FLQEVITTV 2395
            P Y TFDG     QG  +YVL K        V           D  RS + + QEV   +
Sbjct: 1156 PHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHV------TNDDRGRSGVAWTQEVAVLL 1209

Query: 2396 YGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVIS 2455
                V+L     + V+   +A+P+     L V L G  + L     L V + G+    +S
Sbjct: 1210 GDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVS 1269

Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
            +P  Y+G   GLCGN++   ++D+  P G L  +   FGNSW+V                
Sbjct: 1270 VPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQV---------------- 1313

Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVL 2575
             EG         G +V  C      +      R       PF+ CH  V PEPF   CV 
Sbjct: 1314 SEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVY 1373

Query: 2576 DLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            DLC+       +   C  L  YA  C++AG     WR  TLC   C
Sbjct: 1374 DLCACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCVVGC 1418



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 43/136 (31%), Positives = 51/136 (37%), Gaps = 29/136 (21%)

Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
            CQ +   P L  + S  P  CP   S   CL   S      DG  E  + P+   E C C
Sbjct: 811  CQKKPCPPALCPHPSPGPCFCPVCHS---CL---SQGREHQDG--EEFEGPAGSCEWCRC 862

Query: 2251 QPGYV----------------LSEDKCVPRSQCGCKDAHGGSIPLGKSWV--SSGCTEKC 2292
            Q G V                     C PR + GC  AHG   P G  WV   S C+  C
Sbjct: 863  QAGQVSCVRLQCPPLPCKLQVTERGSCCPRCR-GCL-AHGEEHPEGSRWVPPDSACSS-C 919

Query: 2293 VCTGGAIQCGDFRCPS 2308
            VC  G + C   +C S
Sbjct: 920  VCHEGVVTCARIQCIS 935



 Score = 42.0 bits (97), Expect = 0.008
 Identities = 40/136 (29%), Positives = 51/136 (37%), Gaps = 21/136 (15%)

Query: 2207 CPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS--ACAEGCICQPGYVLSEDK-CVP 2263
            CP    A+     C PSC    +       G + PS  A    C+C  G V  E K C P
Sbjct: 642  CPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701

Query: 2264 -------RSQCGCKDAHGGSIPLGKSWVSS-------GCTEKCVCTGGAIQCGDFRC--P 2307
                   R  C C D  G    LG+S++S+            C C GG + CG   C  P
Sbjct: 702  ALCPFPARGDC-CPDCDGCEY-LGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPP 759

Query: 2308 SGSHCQLTSDNSNSNC 2323
              SH  + S +    C
Sbjct: 760  GCSHPLIPSGHCCPTC 775



 Score = 41.2 bits (95), Expect = 0.014
 Identities = 50/193 (25%), Positives = 61/193 (31%), Gaps = 33/193 (17%)

Query: 1748 PQGPFSQCHQVVPPQSSFASC----VHGQCGTKGDTTALCRSLQAYASLCA-QAGQAPAW 1802
            P  P    H ++P      +C     HG     G+T  L   L    SLC  Q G     
Sbjct: 755  PCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGET--LPDPLDPTCSLCTCQEGSMRCQ 812

Query: 1803 RNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALP----CAESCECQKGHI-LS 1857
            +    CP    P  S  PC  P   +C S        +         E C CQ G +   
Sbjct: 813  KKP--CPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870

Query: 1858 GTSCVPL---------GQC-----GCTDPAGSYHPVGERWYTENTCTRLCTCS----VHN 1899
               C PL         G C     GC    G  HP G RW   ++    C C        
Sbjct: 871  RLQCPPLPCKLQVTERGSCCPRCRGCL-AHGEEHPEGSRWVPPDSACSSCVCHEGVVTCA 929

Query: 1900 NITCFQSTCKPNQ 1912
             I C  S  +P Q
Sbjct: 930  RIQCISSCAQPRQ 942



 Score = 39.3 bits (90), Expect = 0.054
 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 9/96 (9%)

Query: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCG--CTDP 1872
            G +Y    +  PD C++    R    A+ C +   C + + L   SC P G+C   C   
Sbjct: 142  GQTYGNGETFSPDACTTC---RCLTGAVQC-QGPSCSELNCLE--SCTPPGECCPICCTE 195

Query: 1873 AGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC 1908
             GS+   G+ W T     R+C C +  +I C Q  C
Sbjct: 196  GGSHWEHGQEWTTPGDPCRICRC-LEGHIQCRQREC 230



 Score = 37.0 bits (84), Expect = 0.27
 Identities = 59/263 (22%), Positives = 87/263 (33%), Gaps = 49/263 (18%)

Query: 2105 PSCQSLLVDEQQIPA-EQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFL 2163
            PSC   L   ++  + E+  +P+  C           CE    AP      +R D  P  
Sbjct: 657  PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCP-- 714

Query: 2164 VDCANTLCEF-GGLYQA------------LCQALQAFGATCQSQGLKPPLWRNSSFCPLE 2210
             DC    CE+ G  Y +            LC  L  F  TC  +  +PP   +       
Sbjct: 715  -DCDG--CEYLGESYLSNQEFPDPREPCNLCTCLGGF-VTCGRRPCEPPGCSH------- 763

Query: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSAC---AEGCICQPGYVLSEDKCVPRSQC 2267
             P   S  +C P+C    +       G  +P         C CQ G +  + K  P + C
Sbjct: 764  -PLIPS-GHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALC 821

Query: 2268 GCKDAHGGSIPLGKSWVS--------------SGCTEKCVCTGGAIQCGDFRCPSGSHCQ 2313
                      P+  S +S              +G  E C C  G + C   +CP    C+
Sbjct: 822  PHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPP-LPCK 880

Query: 2314 LTSDNSNSNCVSDKSEQCSVYGD 2336
            L      S C   +   C  +G+
Sbjct: 881  LQVTERGSCC--PRCRGCLAHGE 901



 Score = 35.4 bits (80), Expect = 0.77
 Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 14/90 (15%)

Query: 2248 CICQPGYVLSEDKCVP----------RSQCGCKDAHGGSIPLGKSWVSSG--CTEKCVCT 2295
            C CQ G V  E++  P          R  C   +  G     G  W   G  CT  CVC 
Sbjct: 334  CSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTA-CVCQ 392

Query: 2296 GGAIQCGDFRCPSGSHCQLTSDNSNSNCVS 2325
             G  +CG   CP  + CQ  +    + C S
Sbjct: 393  DGVPKCGAVLCPP-APCQHPTQPPGACCPS 421



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 20/89 (22%)

Query: 1045 PPNARYESCACPAS-CKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYE 1103
            P  AR+E  AC A  C+     CGP                 HC       C  N   Y 
Sbjct: 104  PEGARWEPDACTACVCQDGAAHCGPQAHLP------------HCR-----GCSQNGQTYG 146

Query: 1104 PGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
             G E FSP+    CRC  G+ V+CQ   C
Sbjct: 147  NG-ETFSPDACTTCRCLTGA-VQCQGPSC 173



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 32/136 (23%), Positives = 45/136 (33%), Gaps = 43/136 (31%)

Query: 1809 PMRCPPGSSYSPCSSPCPDTCSSINNPRDC----------------PKALPCAESCECQK 1852
            P  CP     +PC+ P P TC     P DC                P        C C  
Sbjct: 518  PRPCPR----APCAHPLPGTCC----PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLS 569

Query: 1853 GHI-LSGTSCVPL---------GQC--------GCTDPAGSYHPVGERWYTENTCTRLCT 1894
            G++      CVPL         G+C        GC  P  ++    E +       R C 
Sbjct: 570  GNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCL 629

Query: 1895 CSVHNNITCFQSTCKP 1910
            C +  +++C +  C P
Sbjct: 630  C-LDGSVSCQRLPCPP 644



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 30/108 (27%), Positives = 42/108 (38%), Gaps = 17/108 (15%)

Query: 1426 CPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV---------LSGLE-CIP 1475
            C P +    C     +    G    F  D C   C C  G V         L+ LE C P
Sbjct: 126  CGPQAHLPHCRGCSQNGQTYGNGETFSPDACT-TCRCLTGAVQCQGPSCSELNCLESCTP 184

Query: 1476 RSQCG--CLHPAGSYFKVGERWYKPG--CKELCVCESNNRIRCQPWRC 1519
              +C   C    GS+++ G+ W  PG  C+ +C C     I+C+   C
Sbjct: 185  PGECCPICCTEGGSHWEHGQEWTTPGDPCR-ICRC-LEGHIQCRQREC 230


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score =  213 bits (542), Expect = 2e-54
 Identities = 293/1094 (26%), Positives = 404/1094 (36%), Gaps = 104/1094 (9%)

Query: 521  VVAMGFIL---INPGTCPVKVLPELPPVSPVSSTGPSE---TTGLTENPTISTKKPTVSI 574
            V+ M F L   IN   C     P     +   +  P+    TT +T  PT ++ + T   
Sbjct: 1278 VIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT 1337

Query: 575  EKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPT 634
               + TT  PT        PT  P I+T     P+  P       T P    T +T  PT
Sbjct: 1338 PITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1396

Query: 635  IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTE 694
             P+   T P+  P I+T     PT  PT     TTT      I T     PT  P+  T+
Sbjct: 1397 -PTGTQT-PTSTP-ITTTTTVTPTPTPTGTQTPTTTP-----ITTTTTVTPTPTPT-GTQ 1447

Query: 695  KPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTI 754
             PT +   T  ST  PT +P     PT  P   T   T +P    T T  PT  T   T+
Sbjct: 1448 APTPTAITTT-STVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTV 1506

Query: 755  SPEKPTTPTEKPTISPEKLT---IPTEKPT---------IPTEKPTIPTEKPTISTEEPT 802
            +P    T T+ PT +P   T    PT  PT         I T     PT  PT +    T
Sbjct: 1507 TPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTT 1566

Query: 803  TPTEETTISTEKPS-IPMEKPT--LPTEETTTSVEETTISTEKLTI-PMEKPTISTEKPT 858
            TP   TT  T  P+    + PT  L T  TT +   T  ST+  T+ P+   T  T  PT
Sbjct: 1567 TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT 1626

Query: 859  -IPTEKPTISPEKLT---IPTEKLTI-----PTEKPTIPIEETTIST---EKLTIPTEKP 906
               T+ PT+ P   T    PT   T      PT   T PI E T S    E  T  T + 
Sbjct: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 1686

Query: 907  TISP--EKPT-ISTEKPTI---PTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
            T SP  E  T +ST  P I    T  P+ PT  TT S      P    T SP     PT 
Sbjct: 1687 TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP--GTPTR 1744

Query: 961  KPTI-STEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSP 1019
              T  S+  PT  T + T  +     PT   T    + T LR P+PS        L  + 
Sbjct: 1745 GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLR-PYPSSVLI-CCVLNDTY 1802

Query: 1020 HAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPG 1079
            +AP   + +   G T    + +  C     + + +CP+   +P P+  P         P 
Sbjct: 1803 YAPGEEVYNGTYGDTCYFVNCSLSC--TLEFYNWSCPS---TPSPTPTPSKSTPTPSKPS 1857

Query: 1080 FLFS-DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138
               S      +   C  F  +   +    W+  +C     C   + VE    +C    + 
Sbjct: 1858 STPSKPTPGTKPPECPDF--DPPRQENETWWLCDCF-MATCKYNNTVEIVKVECEPPPMP 1914

Query: 1139 QLKNGQYG---------CHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNS 1189
               NG            C  +     C  +GDPHYVTFDG ++ + G CTY+L +    S
Sbjct: 1915 TCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPS 1974

Query: 1190 TDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-------VGGQQVTLPA 1242
             D F            + VSC  +  +   E+   L+K    +       V  Q V LP 
Sbjct: 1975 VDNFGVYIDNYHCDPNDKVSC-PRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP- 2032

Query: 1243 IPSKGVFLGASG-RFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDND 1301
                G+ +  SG  +V    E G+ V ++G           +     G CG     + +D
Sbjct: 2033 YKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 2092

Query: 1302 HLKLDGSPAGDKEELGNSWQTDQDEDQEC------QKYQVVNSPSCDSSLQSSMSGPG-F 1354
             +   G    + E   + W  +      C       K   V  P    +       P   
Sbjct: 2093 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 2152

Query: 1355 CGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVK 1414
            C  + D+   F  C   V    ++D+C+ D C   G   L C  +      C      + 
Sbjct: 2153 CQLIKDS--LFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNICLD 2209

Query: 1415 PWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV--LSGL 1471
                 H  C + CP + +Y  C      TC S  S    +   VE C C  G +    G 
Sbjct: 2210 WRNHTHGACLVECPSHREYQACGPAEEPTCKSS-SSQQNNTVLVEGCFCPEGTMNYAPGF 2268

Query: 1472 ECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC-ESNNRIRCQPWRCRAQEFCG-QQD 1529
            +   ++ CGC+ P     + GE  ++  CK  CVC E  + I CQP RC  +      +D
Sbjct: 2269 DVCVKT-CGCVGPDNVPREFGEH-FEFDCKN-CVCLEGGSGIICQPKRCSQKPVTHCVED 2325

Query: 1530 GIY-GCHAQGAATC 1542
            G Y       A TC
Sbjct: 2326 GTYLATEVNPADTC 2339



 Score =  166 bits (421), Expect = 2e-40
 Identities = 201/851 (23%), Positives = 318/851 (37%), Gaps = 159/851 (18%)

Query: 1561 MGTCTYV-LTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKV 1619
            M TC+++ ++  C     D  F       +    + +   K  +V VF    S      V
Sbjct: 314  MDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGS------V 367

Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQLC 1677
            +LN  +V LP   A   V  R SS  +++    G++++   + +++  VT+  +  GQ+ 
Sbjct: 368  LLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426

Query: 1678 GLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPS-SCQENSMAD 1736
            GLCGN+N    DD       +          WK   S       +    S + +  + A+
Sbjct: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAE 486

Query: 1737 AWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
             W   C++L   + PF +CH  V P   +  C +  C  + +   LC +L +YA  C   
Sbjct: 487  HW---CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAK 543

Query: 1797 G-QAPAWRNRTFCPM---RCPPGSSYSPCSSPCPDTCSSINN----------PRD---CP 1839
            G     WR    C      CP    +    + C  TC S++           P D   CP
Sbjct: 544  GVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCP 602

Query: 1840 ---------KALPCA---------------------ESCECQKGHI------LSGTSCV- 1862
                     + +P A                     E C C+ G +      L G SC  
Sbjct: 603  DHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTA 662

Query: 1863 PLGQCGCTD-----------------PAGSYH---------PVGERWYTENTCT--RLCT 1894
            P     C++                  AG YH         P G        C   + C 
Sbjct: 663  PKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP 722

Query: 1895 CSVHNN----------ITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDG 1944
            C VHNN          + C   TCK  +  W        +A   G C + G  HY++FDG
Sbjct: 723  C-VHNNDLYSSGAKIKVDCNTCTCKRGR--WVCT-----QAVCHGTCSIYGSGHYITFDG 774

Query: 1945 SNHSIPDACTLVLVK-VCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
              +     C+ V V+  C    +L  F I  ++    G T       + I +   ++ L+
Sbjct: 775  KYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC-GTTGVTCSKAIKIFMGRTELKLE 833

Query: 2004 KGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYG 2063
              HRV+I   +            + +    Y +V    G+ V +D    + I++  +Y G
Sbjct: 834  DKHRVVIQRDE------GHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKG 887

Query: 2064 KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQE 2123
             VCG+CGNF+    ++       V +S+ +F NSWK+    P+C  +             
Sbjct: 888  TVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDV-----------ST 933

Query: 2124 NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA--NTLCEFGGLYQALC 2181
            NP         R   EK  + L++ V++ C S++D  PF   C   +  C+ GG  +  C
Sbjct: 934  NPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFC 993

Query: 2182 QALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSCWDLDGR 2234
             A+ ++   C  +G     WR    CP+ C  Y+        Y  C      +C  ++G 
Sbjct: 994  SAVASYAQECTKEG-ACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGI 1052

Query: 2235 CEGAKVPSACAEGCI--C---QPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGKSWVSSG 2287
                 V  +  EGC   C   +P Y     KCV   +CGC  +D H    P G S  +  
Sbjct: 1053 HSNISV--SYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH---YPPGASVPTEE 1107

Query: 2288 CTEKCVCTGGA 2298
              + CVCT  +
Sbjct: 1108 TCKSCVCTNSS 1118



 Score =  165 bits (417), Expect = 6e-40
 Identities = 126/477 (26%), Positives = 199/477 (41%), Gaps = 79/477 (16%)

Query: 1070 CREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVEC 1127
            C  GCVC  G L  D    C+    C C +NND Y  GA+                +V+C
Sbjct: 697  CVSGCVCPDG-LMDDGRGGCVVEKECPCVHNNDLYSSGAK---------------IKVDC 740

Query: 1128 QISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C 1186
                      C  K G++ C       TC +YG  HY+TFDG+++ F G C+Y+  Q  C
Sbjct: 741  N--------TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 792

Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS 1245
            G NS+   F +  +N   G  GV+C   + + +  + + L    R ++   +    A  +
Sbjct: 793  GQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTT 852

Query: 1246 KGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
            + V     G+++ +++  G+ V WD    +++ ++ +Y G +CGLCGN+D  S+ND    
Sbjct: 853  REV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTR 907

Query: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPF 1365
            D      + + GNSW+    E   C      N   C  +          C  L  +   F
Sbjct: 908  DHMVVSSELDFGNSWK----EAPTCPDVS-TNPEPCSLNPHRRSWAEKQCSILKSS--VF 960

Query: 1366 ETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP 1423
              C   V    F+++C+ D C     G     C+ +++    C   G  V  WR P  CP
Sbjct: 961  SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCP 1019

Query: 1424 MAC----PPNS---KYSLCAKPCPDTC------HSGFSGMF---CSDRCVEACECNPGFV 1467
            + C    PP+     Y  C     +TC      HS  S  +   C  RC +     P + 
Sbjct: 1020 IFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKD---RPIYE 1076

Query: 1468 LSGLECIPRSQCGCLHPAGSYFKVGERWYKPG--------CKELCVCESNNRIRCQP 1516
                +C+   +CGC         V +  Y PG        CK  CVC +++++ C+P
Sbjct: 1077 EDLKKCVTADKCGCY--------VEDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1124



 Score =  164 bits (414), Expect = 1e-39
 Identities = 139/497 (27%), Positives = 206/497 (41%), Gaps = 81/497 (16%)

Query: 1436 AKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGSYFKVGER 1494
            +KP   +C +  +G + ++ CV  C C  G +  G   C+   +C C+H           
Sbjct: 678  SKPRALSCQTLAAGYYHTE-CVSGCVCPDGLMDDGRGGCVVEKECPCVH--------NND 728

Query: 1495 WYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFD 1554
             Y  G K    C   N   C+    R +  C Q      CH     TC+  G  HY+TFD
Sbjct: 729  LYSSGAKIKVDC---NTCTCK----RGRWVCTQAV----CHG----TCSIYGSGHYITFD 773

Query: 1555 GALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISL 1613
            G  + F G C+YV  +  C   S    F +   N   G    V+  KA+ + +    + L
Sbjct: 774  GKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRTELKL 832

Query: 1614 LRGCKVMLN---GHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPS 1670
                +V++    GH VA          T R     +++ ++ G+ V +D    V + +  
Sbjct: 833  EDKHRVVIQRDEGHHVAY---------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAP 883

Query: 1671 SYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQ 1730
            SY G +CGLCGN+++ S +D    D  +    +  G +WK      P C  V   P  C 
Sbjct: 884  SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----EAPTCPDVSTNPEPCS 939

Query: 1731 ENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQ 1787
             N    +W  K C+IL      FS CH  V P+  + +CVH  C   T GD    C ++ 
Sbjct: 940  LNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVA 997

Query: 1788 AYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINN------ 1834
            +YA  C + G    WR    CP+ C    PP      Y PC +   +TC +IN       
Sbjct: 998  SYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1057

Query: 1835 --------PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886
                    PR CPK  P  E  + +K        CV   +CGC     +++P G    TE
Sbjct: 1058 VSYLEGCYPR-CPKDRPIYEE-DLKK--------CVTADKCGCY-VEDTHYPPGASVPTE 1106

Query: 1887 NTCTRLCTCSVHNNITC 1903
             TC + C C+  + + C
Sbjct: 1107 ETC-KSCVCTNSSQVVC 1122



 Score =  133 bits (335), Expect = 2e-30
 Identities = 166/713 (23%), Positives = 256/713 (35%), Gaps = 140/713 (19%)

Query: 2000 VTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV--QVKFDGNHLLEIEI 2057
            V  +    VL+N  QV LP ++    V  + SS + +V++ IGV  QV+      L + +
Sbjct: 359  VVFKSDGSVLLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTL 417

Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117
                 G+V G+CGNFN  E D+    S  V  + + F N+WK +    SC   L      
Sbjct: 418  DQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS---SCHDKL------ 468

Query: 2118 PAEQQENP-SGNCRAADLRRAREKCEAALRAPV-WAQCASRIDLTPFLVDCANTLCEFGG 2175
              +  ++P S N  +A+   A   C    +    + +C S +D   +   C    C    
Sbjct: 469  --DWLDDPCSLNIESANY--AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQN 524

Query: 2176 LYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLE---CPAYSSYTNCLPSCSPSCWDL- 2231
                LC AL ++   C ++G+    WR    C  +   CP    +   L +C  +C  L 
Sbjct: 525  NEDCLCAALSSYARACTAKGVMLWGWREH-VCNKDVGSCPNSQVFLYNLTTCQQTCRSLS 583

Query: 2232 --DGRCEGAKVPSACAEGCICQPGYVLSED-KCVP----------------------RSQ 2266
              D  C     P    +GC C     L E  +CVP                        +
Sbjct: 584  EADSHCLEGFAP---VDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEER 640

Query: 2267 CGCKD----------------------------AHGGSIP-------LGKSWVSSGCTEK 2291
            C C+D                            A   S P       L   +  + C   
Sbjct: 641  CVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSG 700

Query: 2292 CVCTGGAIQCGDFRCPSGSHCQLTSDNSN-----------SNCVSDKSE----------Q 2330
            CVC  G +  G   C     C    +N             + C   +             
Sbjct: 701  CVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGT 760

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
            CS+YG   Y+TFDG  Y   G  +YV ++        +    +   N +    + +   +
Sbjct: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITEN-VPCGTTGVTCSK 819

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLW--GQRLYLVTDFELVVSFGG 2448
             I    G   + +  LE   +  ++ +      H+  T    GQ L + +   ++V +  
Sbjct: 820  AIKIFMG---RTELKLE---DKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDK 873

Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
            R    I L   Y+G V GLCGN+D    ND       +  +   FGNSW           
Sbjct: 874  RTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW----------- 922

Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEP 2568
             +  P   +       + T  +    +P +  S + + C +L      F+ CH  V P+P
Sbjct: 923  -KEAPTCPD-------VSTNPEPCSLNPHR-RSWAEKQCSIL--KSSVFSICHSKVDPKP 971

Query: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
            F E CV D CS  D     E  C  ++ YA  C + GA +  WR   LC   C
Sbjct: 972  FYEACVHDSCSC-DTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFC 1022



 Score =  128 bits (321), Expect = 9e-29
 Identities = 119/455 (26%), Positives = 171/455 (37%), Gaps = 52/455 (11%)

Query: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY--------GC--HAQGAATC 1542
            E W+   C  +  C+ NN +      C         +G+         GC  H +    C
Sbjct: 1883 ETWWLCDCF-MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYC 1941

Query: 1543 TASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFV--------------VSATNE 1588
            T  GDPHY+TFDG  + + G CTYVL     S S D++ V                 T  
Sbjct: 1942 TGWGDPHYVTFDGLYYSYQGNCTYVLVEEI-SPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000

Query: 1589 NRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648
             R    EV  IK VH+    +        +V +N   VALP +   G    +   N V+ 
Sbjct: 2001 VRHETQEV-LIKTVHMMPMQV--------QVQVNRQAVALP-YKKYGLEVYQSGINYVVD 2050

Query: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
                G+ V Y+G           +G    G CG   N + DD + P  ++  +       
Sbjct: 2051 IPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQ 2110

Query: 1709 WKLPESSEPGC---FLVGGKPSSCQENSMADAWNKNCA----ILINPQGPFSQCHQVVPP 1761
            W + + S+P C        +P+           +K+C       +     F+QCH +VPP
Sbjct: 2111 WLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPP 2170

Query: 1762 QSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTF--CPMRCPPGSSYS 1819
            Q  + +CV   C   G +   C SLQAYA+LCAQ      WRN T   C + CP    Y 
Sbjct: 2171 QHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQ 2229

Query: 1820 PCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHP 1878
             C      TC S ++ ++        E C C +G +       V +  CGC  P      
Sbjct: 2230 ACGPAEEPTCKSSSSQQN---NTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286

Query: 1879 VGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913
             GE +  E  C         + I C    C    +
Sbjct: 2287 FGEHF--EFDCKNCVCLEGGSGIICQPKRCSQKPV 2319



 Score =  111 bits (277), Expect = 1e-23
 Identities = 144/566 (25%), Positives = 198/566 (34%), Gaps = 67/566 (11%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 1326 PTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 1382

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T    +T +T   T++        + P+   +TT     P   
Sbjct: 1383 TPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1442

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +   P+   
Sbjct: 1443 PT-GTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAIT 1501

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
            T +T  PT     T+ PT+    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 1502 TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT-PTPTPISTTT--TVTPTPTP 1558

Query: 705  ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761
              T+ PT +P   T    PT  PT     +T+     TT T  PT  + K T      TT
Sbjct: 1559 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTT 1618

Query: 762  PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEK 821
             T   T +P     PT  P I T     PT  PT  +  P T T    I+    S P  +
Sbjct: 1619 TTVTATPTPTGTQTPTMIP-ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPE 1677

Query: 822  PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881
             + P    +TS   T  +T   T+P      ST  P+ PT   T S      P    T  
Sbjct: 1678 SSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT-- 1735

Query: 882  TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI------------ 929
            T  P  P   TT  +     P+   T+     +  T  PT P   P+I            
Sbjct: 1736 TSPPGTPTRGTTTGSSSAPTPS---TVQTTTTSAWTPTPT-PLSTPSIIRTTGLRPYPSS 1791

Query: 930  -------------PTEETTISTE---------KLTIPTEKPTISPEKLTIPTEKPTISTE 967
                         P EE    T           L+   E    S      PT  P+ ST 
Sbjct: 1792 VLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTP 1851

Query: 968  KPTIPTEKLTIPTEKPTIPTEKPTIP 993
             P+ P+        KPT  T+ P  P
Sbjct: 1852 TPSKPSST----PSKPTPGTKPPECP 1873



 Score =  105 bits (261), Expect = 8e-22
 Identities = 96/343 (27%), Positives = 136/343 (39%), Gaps = 42/343 (12%)

Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE-E 1980
            R R  G  VC   G  HY +FDG     P  C       C  +     +K  A H K   
Sbjct: 28   RTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGS-----YKEFAVHLKRGP 82

Query: 1981 GGTEA-FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039
            G  EA   +  + + I D  + L + H  ++N   V+ P  S  PG+ ++ S  Y+ V  
Sbjct: 83   GQAEAPAGVESILLTIKDDTIYLTR-HLAVLNGAVVSTPHYS--PGLLIEKSDAYTKVYS 139

Query: 2040 KIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK 2099
            + G+ + ++    L +E+ T +    CG+CG++N  +     + SD V  S  EF N  K
Sbjct: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNMQK 198

Query: 2100 DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159
                D  C+    +E+  PA   E+             R +CE  L A  +A C   + L
Sbjct: 199  INQPDVVCED--PEEEVAPASCSEH-------------RAECERLLTAEAFADCQDLVPL 243

Query: 2160 TPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRN-----SSFCPLECPAY 2214
             P+L  C    C   G    +C  +  F   C   G +P  WR      S      CP  
Sbjct: 244  EPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGN 303

Query: 2215 SSYTNCLPSCSPSCWDLDGRCEGAKVPSACAE----GCICQPG 2253
              Y   L S SP C D    C   +V S C E    GC C  G
Sbjct: 304  LVY---LESGSP-CMD---TCSHLEVSSLCEEHRMDGCFCPEG 339



 Score =  103 bits (258), Expect = 2e-21
 Identities = 83/322 (25%), Positives = 130/322 (40%), Gaps = 23/322 (7%)

Query: 1152 GTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211
            G   C  +G+ HY TFDG  F F G C Y  A  C  S   F  V  K      E  + +
Sbjct: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEF-AVHLKRGPGQAEAPAGV 91

Query: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271
              + +T+ + T+ L +    ++ G  V+ P   S G+ +  S  + ++ +  GL + W+ 
Sbjct: 92   ESILLTIKDDTIYLTR-HLAVLNGAVVSTPHY-SPGLLIEKSDAYTKVYSRAGLTLMWNR 149

Query: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG---SPAGDKEELGNSWQTDQDEDQ 1328
            +  L + + + +    CGLCG+Y+G         DG   SP     E GN  + +Q  D 
Sbjct: 150  EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL----EFGNMQKINQ-PDV 204

Query: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388
             C+  +   +P+  S  ++       C RL+ T   F  C   V    +  +C  D C  
Sbjct: 205  VCEDPEEEVAPASCSEHRAE------CERLL-TAEAFADCQDLVPLEPYLRACQQDRCRC 257

Query: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHF-----CPMACPPNSKYSLCAKPCPDTC 1443
             G    +C+ ++  +  C  AG     WR             CP N  Y     PC DTC
Sbjct: 258  PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTC 317

Query: 1444 HSGFSGMFCSDRCVEACECNPG 1465
                    C +  ++ C C  G
Sbjct: 318  SHLEVSSLCEEHRMDGCFCPEG 339



 Score =  102 bits (255), Expect = 4e-21
 Identities = 90/358 (25%), Positives = 145/358 (40%), Gaps = 31/358 (8%)

Query: 1185 PCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLV----------G 1234
            PC + T     V++  EE   +G  C       LP++ V L   ++ +V           
Sbjct: 312  PCMD-TCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLLN 370

Query: 1235 GQQVTLPAIPSKGVFLGASGRFVELQTEFGLR--VRWDGDQQLYVTVSSTYSGKLCGLCG 1292
              QV LP + +       S   + +    G+R  V+     QL+VT+     G++ GLCG
Sbjct: 371  ELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCG 430

Query: 1293 NYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSMSG 1351
            N++G   +D     G          N+W+        C  K   ++ P C  +++S+   
Sbjct: 431  NFNGLEGDDFKTASGLVEATGAGFANTWKAQSS----CHDKLDWLDDP-CSLNIESANYA 485

Query: 1352 PGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGH 1411
              +C  L  T  PF  C   V  A ++  C  D C  Q  +  LC  +S+    C   G 
Sbjct: 486  EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 545

Query: 1412 AVKPWREPHFCPM---ACPPNSKYSLCAKPCPDTCHS-GFSGMFCSD--RCVEACEC-NP 1464
             +  WRE H C     +CP +  +      C  TC S   +   C +    V+ C C + 
Sbjct: 546  MLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDH 604

Query: 1465 GFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQ 1522
             F+     C+P ++C C H  G Y + G+   +   +E CVC  + R+ C+  R   Q
Sbjct: 605  TFLDEKGRCVPLAKCSCYH-RGLYLEAGDVVVRQ--EERCVCR-DGRLHCRQIRLIGQ 658



 Score =  100 bits (250), Expect = 1e-20
 Identities = 113/488 (23%), Positives = 184/488 (37%), Gaps = 68/488 (13%)

Query: 1892 LCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP----------GESHYVS 1941
            + TC  +N +   +  C+P  +    +GL   R      C             G+ HYV+
Sbjct: 1892 MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVT 1951

Query: 1942 FDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH----EKEEGGTEAFRLHEVYIDIYD 1997
            FDG  +S    CT VLV+   P++      I   H    +K          HE    +  
Sbjct: 1952 FDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIK 2011

Query: 1998 AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI-KIGVQVKFDGNHLLEIE 2056
                +    +V +N + V LP      G+ V  S I  +V+I ++GV V ++G     + 
Sbjct: 2012 TVHMMPMQVQVQVNRQAVALPYKKY--GLEVYQSGINYVVDIPELGVLVSYNGLS-FSVR 2068

Query: 2057 IPTTYYG-KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD-IDPSCQSLLVDE 2114
            +P   +G    G CG   +   D+ ++PS E+ ++     + W   D   P C       
Sbjct: 2069 LPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTT 2128

Query: 2115 QQ----IPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL 2170
            ++    +P   +  P  +C  + L      C+  ++  ++AQC + +    +   C    
Sbjct: 2129 KRPAVTVPGGGKTTPHKDCTPSPL------CQ-LIKDSLFAQCHALVPPQHYYDACVFDS 2181

Query: 2171 CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF--CPLECPAYSSYTNCLPSCSPSC 2228
            C   G     C +LQA+ A C  Q +    WRN +   C +ECP++  Y  C P+  P+C
Sbjct: 2182 CFMPG-SSLECASLQAYAALCAQQNICLD-WRNHTHGACLVECPSHREYQACGPAEEPTC 2239

Query: 2229 WDLDGRCEGAKVPSACAEGCICQPG---YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVS 2285
                 +       +   EGC C  G   Y    D CV    CGC          G+ +  
Sbjct: 2240 KSSSSQQNN----TVLVEGCFCPEGTMNYAPGFDVCV--KTCGCVGPDNVPREFGEHFEF 2293

Query: 2286 SGCTEKCVCT--GGAIQCGDFRC--------------------PSGSHCQLTSDNSNSNC 2323
                + CVC   G  I C   RC                    P+ + C +T    N++ 
Sbjct: 2294 D--CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSL 2351

Query: 2324 VSDKSEQC 2331
              +K   C
Sbjct: 2352 CKEKPSVC 2359



 Score = 99.4 bits (246), Expect = 4e-20
 Identities = 132/525 (25%), Positives = 187/525 (35%), Gaps = 79/525 (15%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTST---PITTTTTVTPTPTPTGTQTPTT 1428

Query: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
             P+     + P    + T     T +T   T++        + P+   +TT     P   
Sbjct: 1429 TPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1488

Query: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
            PT  T+ PT   I+T     P+  P       + P    T +T  PT    +   P+   
Sbjct: 1489 PT-GTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPIS 1547

Query: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPT--EKPS---IPTEKPSIPTEKPT-- 697
            T +T  PT     T+ PTT    TTT++     PT  + P+   I T     PT  PT  
Sbjct: 1548 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTST 1607

Query: 698  -------ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTE 750
                   I+   T+ +T  PT +     IP    T  T   T +      PT   T P  
Sbjct: 1608 KSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIA 1667

Query: 751  KPTIS---PEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEE 807
            + T S   PE  T  T + T SP      TE  T+ +   T+P      ST  P+TPT  
Sbjct: 1668 ELTTSNPPPESSTPQTSRSTSSPL-----TESTTLLS---TLPPAIEMTSTAPPSTPTAP 1719

Query: 808  TTIS-----TEKPSIPMEKPTLPTEETTT---------SVEETTISTEKLT-IPMEKPTI 852
            TT S     +  PS     P  PT  TTT         +V+ TT S    T  P+  P+I
Sbjct: 1720 TTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSI 1779

Query: 853  STEKPTIPTEKPT----ISPEKLTIPTEKL------------------TIPTEKPTIPIE 890
                   P         +  +    P E++                  T+     + P  
Sbjct: 1780 IRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPST 1839

Query: 891  ETTISTEKLTIPT-EKPTISPEKPTISTEKPTIPTEKPTIPTEET 934
             +   T   + PT  KP+ +P KPT  T+ P  P   P     ET
Sbjct: 1840 PSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENET 1884



 Score = 95.1 bits (235), Expect = 8e-19
 Identities = 80/294 (27%), Positives = 126/294 (42%), Gaps = 29/294 (9%)

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIK----TVDVLPEGVEPLLVEGRNKMDPPRSSI 2386
            C+ +GDP Y+TFDG  Y  QG  TYVL++    +VD     ++    +  +K+  PR+ I
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000

Query: 2387 FLQE----VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYL-VTDFE 2441
               E    +I TV+   +Q+Q    + VN Q +A+PY+    L V   G    + + +  
Sbjct: 2001 VRHETQEVLIKTVHMMPMQVQ----VQVNRQAVALPYK-KYGLEVYQSGINYVVDIPELG 2055

Query: 2442 LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKT 2501
            ++VS+ G   +V      +     G CG       +D +LPSG +  N     + W V  
Sbjct: 2056 VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV-N 2114

Query: 2502 EDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACH 2561
            + +    P +    +       G        +C+P  L       C+++ D    FA CH
Sbjct: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL-------CQLIKD--SLFAQCH 2165

Query: 2562 QTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRT 2615
              V P+ + + CV D C          L C  L  YA LC +    L  WR+ T
Sbjct: 2166 ALVPPQHYYDACVFDSCFMPG----SSLECASLQAYAALCAQQNICL-DWRNHT 2214



 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 82/327 (25%), Positives = 132/327 (40%), Gaps = 31/327 (9%)

Query: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVS 1597
            G   C+  G+ HY TFDG +  F G C Y     C  R     F V       G     +
Sbjct: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVH-LKRGPGQAEAPA 89

Query: 1598 YIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
             ++++ +T+ D +I L R   V LNG  V+ P +     + I  S     +Y+  GL + 
Sbjct: 90   GVESILLTIKDDTIYLTRHLAV-LNGAVVSTPHY--SPGLLIEKSDAYTKVYSRAGLTLM 146

Query: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYN-----NNSLDDNLRPDRKLAGDSMQLGAAWKLP 1712
            ++    + + + + +    CGLCG+YN     +  L D +       G+  ++     + 
Sbjct: 147  WNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVC 206

Query: 1713 ESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQ 1772
            E  E         P+SC E+         C  L+  +  F+ C  +VP +    +C   +
Sbjct: 207  EDPEEEV-----APASCSEH------RAECERLLTAEA-FADCQDLVPLEPYLRACQQDR 254

Query: 1773 CGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF-----CPMRCPPGSSYSPCSSPCP 1826
            C   G  T +C ++  ++  C+ AG  P  WR  T          CP    Y    SPC 
Sbjct: 255  CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314

Query: 1827 DTCSSINNPRDCPKALPCAESCECQKG 1853
            DTCS +     C +     + C C +G
Sbjct: 315  DTCSHLEVSSLCEEHR--MDGCFCPEG 339



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 99/375 (26%), Positives = 134/375 (35%), Gaps = 75/375 (20%)

Query: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQ-LIFKGIQGSNTASVVAMGFILINPG 532
            P P   +  +  P    T+VT    P+G Q P   LI      + T +  +     + P 
Sbjct: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPI 1615

Query: 533  TC-------PVKVLPELPPVSPVSSTG-----PSETTGLTENPTISTKKPTVSIEKPSVT 580
            T        P     + P + P+S+T      P+ TTG T  PT ++  P   +     T
Sbjct: 1616 TTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAEL-----T 1670

Query: 581  TEKPTVPKEKPTIPTEKPTIS--TEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSE 638
            T  P  P E  T  T + T S  TE  T+ S  P       T P   PT     PT  S 
Sbjct: 1671 TSNP--PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA----PTTTSG 1724

Query: 639  KPTIPSEKPTISTEKPTVPTEEPTT-----PT----EETTTSMEEPV-IPTEKPSI---- 684
              T+ S  P+ +T  P  PT   TT     PT    + TTTS   P   P   PSI    
Sbjct: 1725 GHTL-SPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTT 1783

Query: 685  ---------------------PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEK 723
                                 P E+    T   T       +S      +   P+ P+  
Sbjct: 1784 GLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT 1843

Query: 724  PTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPT-------ISPEKLTIP 776
            PT    KST +P KP++   KPT P  KP   P+      E  T       ++  K    
Sbjct: 1844 PT--PSKSTPTPSKPSSTPSKPT-PGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNT 1900

Query: 777  TEKPTIPTEKPTIPT 791
             E   +  E P +PT
Sbjct: 1901 VEIVKVECEPPPMPT 1915



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 71/328 (21%), Positives = 117/328 (35%), Gaps = 36/328 (10%)

Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
            CS +G+  Y TFDG  +R  G   Y          +     L  G  + + P     ++ 
Sbjct: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAG---VES 93

Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVP-YRPNEHLRVTLWGQRLYLVTDFELVVSFGGR 2449
            ++ T+    + L   L  V+N   ++ P Y P   +  +    ++Y      L+ +   R
Sbjct: 94   ILLTIKDDTIYLTRHLA-VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWN---R 149

Query: 2450 KNAV-ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
            ++A+ + L + +     GLCG+Y+  +     L  G L   L  FGN  ++   D +   
Sbjct: 150  EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCED 208

Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEP 2568
            P                       E +P   + +  +  R+L      FA C   V  EP
Sbjct: 209  PE---------------------EEVAPASCSEHRAECERLLTAEA--FADCQDLVPLEP 245

Query: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQN 2628
            +   C  D C        +   C  ++ ++  C  AG     WR  T   SP     C  
Sbjct: 246  YLRACQQDRCRCPGG---DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPG 302

Query: 2629 DGQCREQGATFTCECEVGYGGGLCMEPR 2656
            +    E G+     C       LC E R
Sbjct: 303  NLVYLESGSPCMDTCSHLEVSSLCEEHR 330


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score =  207 bits (527), Expect = 1e-52
 Identities = 192/731 (26%), Positives = 298/731 (40%), Gaps = 69/731 (9%)

Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
            C  +G  H+ TFD   + F G C YI A  C ++  P F V  +    G      +S++ 
Sbjct: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAF-PTFSVQLRRGPDGS-----ISRII 98

Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL---GASGRFVELQTEFGLRVRWDGD 1272
            V L  S VT+ +   ++     ++LP   S G+ +   G S R V  Q E  L V W  D
Sbjct: 99   VELGASVVTVSEAIISVKDIGVISLP-YTSNGLQITPFGQSVRLVAKQLELELEVVWGPD 157

Query: 1273 QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQK 1332
              L V V   Y G++CGLCGN+DG   N+ +  +G      E    +     D+  E   
Sbjct: 158  SHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL---EPHKFAALQKLDDPGEICT 214

Query: 1333 YQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ--G 1390
            +Q + S     +  + +     C +L+    P   C   V    F  SC  D+      G
Sbjct: 215  FQDIPSTHVRQAQHARI-----CTQLLTLVAP--EC--SVSKEPFVLSCQADVAAAPQPG 265

Query: 1391 LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMA-CPPNSKYSLCAKPCPDTCHSGFSG 1449
             Q+  C  +S  +  C   G  V+ WR P  C +  CP N  Y  C   C  TC +    
Sbjct: 266  PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHS 325

Query: 1450 MFCSDRCVEACECNPGFVLSGLE----CIPRSQCGC-LHPAGSYFKVGERWYKPGCKELC 1504
              CS  C   C C  G VL+ L     C+P +QC C LH A          Y PG   + 
Sbjct: 326  --CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGA---------MYAPGEVTIA 374

Query: 1505 VCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTC 1564
             C++  R     W C  +   G               C+  G     TFD   + F GTC
Sbjct: 375  ACQTC-RCTLGRWVCTERPCPGH--------------CSLEGGSFVTTFDARPYRFHGTC 419

Query: 1565 TYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGH 1624
            TY+L +    +  +   +++  +++     E S +  V+++  D  I + +   V  NG 
Sbjct: 420  TYILLQS--PQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQD-KIVISQDEVVTNNGE 476

Query: 1625 RVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQLCGLCGN 1682
               LP +  +     R +S  + + T+FGL++      + +  VTV   + GQ  GLCGN
Sbjct: 477  AKWLP-YKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535

Query: 1683 YNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNC 1742
            +N ++ DD         G +     +W+      P        P S  + +   A   +C
Sbjct: 536  FNGDTTDDFTTSMGIAEGTASLFVDSWRAGNC--PAALERETDPCSMSQLNKVCA-ETHC 592

Query: 1743 AILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP-A 1801
            ++L+     F +CH  V P   +  CV+  C  +     +C +L  Y   C+  G     
Sbjct: 593  SMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWG 652

Query: 1802 WRNRT-FCPMRCPPGSSYSPCSSPCPDTCSSINN-PRDCPKALPCAESCECQKGHILSGT 1859
            WR+    C + C   +++S  S  C  TC S+++   +C  +    + C C  G  L+  
Sbjct: 653  WRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQK 712

Query: 1860 -SCVPLGQCGC 1869
              CV   QC C
Sbjct: 713  GECVRKAQCPC 723



 Score =  206 bits (525), Expect = 2e-52
 Identities = 221/948 (23%), Positives = 345/948 (36%), Gaps = 153/948 (16%)

Query: 971  IPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSV- 1029
            I T+ LT+   + ++  E P + + +      P P P  +  A L  S ++    M    
Sbjct: 231  ICTQLLTLVAPECSVSKE-PFVLSCQADVAAAPQPGPQNSSCATL--SEYSRQCSMVGQP 287

Query: 1030 ILGTTTTSRSSTERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVCNPGFLFSD--- 1084
            +    +    S  +CP N  Y+ C  AC  +C +P+ SC   C  GC C  G + +D   
Sbjct: 288  VRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSN 347

Query: 1085 NH-CIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
            NH C+  + C C  +   Y PG    +    + CRC  G  V C    C  H  C L+ G
Sbjct: 348  NHTCVPVTQCPCVLHGAMYAPGEVTIA--ACQTCRCTLGRWV-CTERPCPGH--CSLEGG 402

Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
             +                    TFD R + F G CTYIL Q      D            
Sbjct: 403  SF------------------VTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGV 444

Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEF 1263
                 S ++ VY++  +  V + +       G+   LP           +   +++ T F
Sbjct: 445  SHSETSLVAVVYLSRQDKIV-ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSF 503

Query: 1264 GLR--VRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQ 1321
            GL   V+     Q YVTV   + G+  GLCGN++G++ +D     G   G      +SW+
Sbjct: 504  GLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWR 563

Query: 1322 TDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSC 1381
                    C       +  C  S  + +     C  L+ T   FE C   V  A F+  C
Sbjct: 564  AG-----NCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRC 618

Query: 1382 MLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREP-HFCPMACPPNSKYSLCAKPCP 1440
            +   C ++     +C  +      C   G  +  WR     C + C  N+ +S  ++ C 
Sbjct: 619  VYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACE 678

Query: 1441 DTCHSGFSGMFCSDRC---------VEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFK 1490
             TC S       SDR          V+ C C  G  L+   EC+ ++QC C+     +  
Sbjct: 679  RTCLS------LSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFIL 732

Query: 1491 VGERWYKPGCKELCVCESNNRIRCQPWR-------CRAQ---EFCGQ-QDGIYGCH---- 1535
              +     G    C+   N R+ C P R       C+A    + C Q  +  +G      
Sbjct: 733  AEQSTVINGITCHCI---NGRLSC-PQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPT 788

Query: 1536 ----AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC------------------- 1572
                A G A      +P  +  +G   +  G C      PC                   
Sbjct: 789  CQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRT 848

Query: 1573 -------WSRSQDSYFVVSATNENRGGIL-----------EVSYIKAV------------ 1602
                   W+  Q ++   + T    G ++              YI A             
Sbjct: 849  CSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTF 908

Query: 1603 -----HVTVFDLSISLLRGCKVMLNGHRVAL-----PVWLAQGRVTIRLSSNLVLLYTNF 1652
                 +V   +  ++  R  K+ L G  V L      V   +  V + ++   + L  + 
Sbjct: 909  KILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVDI 968

Query: 1653 GLQVRYD-----GSHL-VEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLG 1706
             +  RY+       H+ + + +  +    LCGLCGN+N N  DD     R +A   ++L 
Sbjct: 969  SIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELV 1028

Query: 1707 AAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFA 1766
             +WK      P C  V      C  N+   +W +    +IN Q  F+ CH  V     + 
Sbjct: 1029 NSWK----ESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQ-TFATCHSKVYHLPYYE 1083

Query: 1767 SCVHGQCG--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
            +CV   CG  + GD   LC ++ AYA  C   G    WR   FCP+ C
Sbjct: 1084 ACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYC 1131



 Score =  167 bits (422), Expect = 2e-40
 Identities = 180/775 (23%), Positives = 302/775 (38%), Gaps = 81/775 (10%)

Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY--FVVSATNENRGGILEVSYI 1599
            C+  G  H+ TFD  ++ F GTC Y+    C    +D++  F V       G I  +   
Sbjct: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATC----KDAFPTFSVQLRRGPDGSISRIIVE 100

Query: 1600 KAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVT-IRLSSNLVLLYTNFGLQVRY 1658
                V     +I  ++   V      ++LP      ++T    S  LV       L+V +
Sbjct: 101  LGASVVTVSEAIISVKDIGV------ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVW 154

Query: 1659 DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPG 1718
                 + V V   Y GQ+CGLCGN++    ++ +  + K   +  +  A  KL +  E  
Sbjct: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213

Query: 1719 CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGD 1778
             F     PS+    +           L+ P+   S+   V+  Q+  A+         G 
Sbjct: 214  TF--QDIPSTHVRQAQHARICTQLLTLVAPECSVSKEPFVLSCQADVAAAPQ-----PGP 266

Query: 1779 TTALCRSLQAYASLCAQAGQ-APAWRNRTFCPM-RCPPGSSYSPCSSPCPDTCSSINNPR 1836
              + C +L  Y+  C+  GQ    WR+   C + +CP    Y  C S C  TCS  N   
Sbjct: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCS--NPQH 324

Query: 1837 DCPKALPCAESCECQKGHILSGTS----CVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
             C  +  C   C C +G +L+  S    CVP+ QC C      Y P GE   T   C + 
Sbjct: 325  SCSSS--CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAP-GE--VTIAAC-QT 378

Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
            C C++     C +  C                    G C L G S   +FD   +     
Sbjct: 379  CRCTL-GRWVCTERPCP-------------------GHCSLEGGSFVTTFDARPYRFHGT 418

Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINS 2012
            CT +L++   P +      ++   +     +E   +  VY+   D ++ + +   V  N 
Sbjct: 419  CTYILLQ--SPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQD-KIVISQDEVVTNNG 475

Query: 2013 KQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
            +   LP     I      S+ +    +  + + V+        + +   + G+  G+CGN
Sbjct: 476  EAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535

Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
            FN +  D+          + S FV+SW+      +C + L        E++ +P   C  
Sbjct: 536  FNGDTTDDFTTSMGIAEGTASLFVDSWR----AGNCPAAL--------ERETDP---CSM 580

Query: 2132 ADLRR--AREKCEAALR-APVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFG 2188
            + L +  A   C   LR   V+ +C + ++  PF   C    C +   +  +C AL  + 
Sbjct: 581  SQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYV 640

Query: 2189 ATCQSQGLKPPLWRNS-SFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
              C  +G+    WR+S   C + C   ++++    +C  +C  L  R       +   +G
Sbjct: 641  HACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDG 700

Query: 2248 CICQPG-YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301
            C C  G Y+  + +CV ++QC C       I   +S V +G T  C C  G + C
Sbjct: 701  CNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGIT--CHCINGRLSC 753



 Score =  159 bits (403), Expect = 3e-38
 Identities = 160/708 (22%), Positives = 264/708 (37%), Gaps = 95/708 (13%)

Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988
            G C   G  H+ +FD   +     C  +    C  A   P F +  +   +        +
Sbjct: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAF--PTFSVQLRRGPDGS------I 94

Query: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN-IKIGVQVKF 2047
              + +++  + VT+ +    + +   ++LP  S    ++    S+  +   +++ ++V +
Sbjct: 95   SRIIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVW 154

Query: 2048 DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSC 2107
              +  L + +   Y G++CG+CGNF+ +  +E +       + + +F+   K   +    
Sbjct: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFV-------SEEGKFLEPHKFAALQK-- 205

Query: 2108 QSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA 2167
                +D+       Q+ PS + R A   R    C   L   V  +C+  +   PF++ C 
Sbjct: 206  ----LDDPGEICTFQDIPSTHVRQAQHARI---CTQLLTL-VAPECS--VSKEPFVLSCQ 255

Query: 2168 NTLCEFG--GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPL-ECPAYSSYTNCLPSC 2224
              +      G   + C  L  +   C   G     WR+   C + +CPA   Y  C  +C
Sbjct: 256  ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC 315

Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSE----DKCVPRSQCGCKDAHGGSIPLG 2280
              +C +    C      S+C  GC C  G VL++      CVP +QC C   HG     G
Sbjct: 316  VKTCSNPQHSCS-----SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPG 369

Query: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
            +  V+    + C CT G   C +  CP                       CS+ G     
Sbjct: 370  E--VTIAACQTCRCTLGRWVCTERPCPG---------------------HCSLEGGSFVT 406

Query: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
            TFD   YR  G  TY+L+++  +  +G    L+   +K     S   L  V+      K+
Sbjct: 407  TFDARPYRFHGTCTYILLQSPQLPEDGA---LMAVYDKSGVSHSETSLVAVVYLSRQDKI 463

Query: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDF--ELVVSFGGRKNAVISLPS 2458
             +     +  N +   +PY+             L + T F  ELVV       A +++  
Sbjct: 464  VISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGP 523

Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEG 2518
             + G   GLCGN++ +  +D     G      + F +SW           P A+  E + 
Sbjct: 524  QFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAG------NCPAALERETD- 576

Query: 2519 QGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDL 2577
                           CS  QL     +  C +L      F  CH TV P PF + CV   
Sbjct: 577  --------------PCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQA 622

Query: 2578 CSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRT-LCESPCLQN 2624
            C+ +   E     C  L  Y   C   G  L GWR     C  PC  N
Sbjct: 623  CNYE---ETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGN 667



 Score =  112 bits (281), Expect = 4e-24
 Identities = 146/558 (26%), Positives = 208/558 (37%), Gaps = 68/558 (12%)

Query: 539  LPELPPVSPVSSTGPS-ETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEK 597
            +P +PP +P   T P   TTG            + +I   S T   P+     P  PT+ 
Sbjct: 1194 VPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPS-SNHTPASPTQT 1252

Query: 598  PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTI--STEKPT 655
            P +     T+ S KP   S +P  P+   T        P+      + KPT+  +T + T
Sbjct: 1253 PLLPA---TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRAT 1309

Query: 656  VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIP----------TEKPTISMEETII 705
              T  P T +   +T+     +PT  P+     P++P          T   T     T  
Sbjct: 1310 ASTASPATTSTAQSTTRTTMTLPT--PATSGTSPTLPKSTNQELPGTTATQTTGPRPTPA 1367

Query: 706  STEKPTI-SPEKPTIPTEKPTIPTEKST--ISPEKPTTPTEKPTIPTEKPTISPEKPTT- 761
            ST  PT   P +PT PT   T  T  +T   +P+ P T    PT  +  P+  P   T+ 
Sbjct: 1368 STTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSF 1427

Query: 762  --PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP- 818
               T  PT S  + T+PT  P   T   T P+    I+       T  +  S    +IP 
Sbjct: 1428 HATTTYPTPSHPETTLPTHVPPFSTSLVT-PSTHTVITPTHAQMATSASNHSAPTGTIPP 1486

Query: 819  ----------MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI-PTEKPTIS 867
                         P +    + TS   ++ ST K    +   T ST  P + PT   TI+
Sbjct: 1487 PTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTIT 1546

Query: 868  PEKLTIPTEKLTIPTEKPTI---PIEETT----------ISTEKLTIPTEKPTISPEKPT 914
            P   +  T      T   T    P   TT           ST  +T  + K T +   PT
Sbjct: 1547 PNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTT--YPT 1604

Query: 915  ISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKL------TIP---TEKPTIS 965
             S  + T+PT  P   T   T ST  +  PT     +   +      TIP   T K T S
Sbjct: 1605 PSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGS 1664

Query: 966  TEKPTIPTEKLTIPTEK---PTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAP 1022
            T   T PT  LT         ++ T K +      T+    H   T+T    +  +P + 
Sbjct: 1665 TH--TAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTS-STHHAEATSTSTTNITPNPTST 1721

Query: 1023 STPMTSVILGTTTTSRSS 1040
             TP  +V    T+ SRSS
Sbjct: 1722 GTPPMTVTTSGTSQSRSS 1739



 Score =  111 bits (278), Expect = 8e-24
 Identities = 110/442 (24%), Positives = 173/442 (39%), Gaps = 81/442 (18%)

Query: 1805 RTFCPMR-------CPPGSSYSPCS--------SPCPDTCSSINNPRDCPKALPCAESCE 1849
            R  CP R       C    ++  CS        + C  TC  +     C     C   C 
Sbjct: 750  RLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPT-KCEPGCV 808

Query: 1850 CQKG-HILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC 1908
            C +G +  +   CVP  +C C     SY P G   +T+    R C+CS      C Q T 
Sbjct: 809  CAEGLYENADGQCVPPEECPCEFSGVSY-PGGAELHTD---CRTCSCS-RGRWACQQGTH 863

Query: 1909 KPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVK-VCHPAMAL 1967
             P+                   C L GE H ++FDG        C  +L   VC    + 
Sbjct: 864  CPS------------------TCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ 905

Query: 1968 PFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGV 2026
            P FKI  ++      G    R  ++++           G  V++  +  T+        +
Sbjct: 906  PTFKILTENVICGNSGVTCSRAIKIFLG----------GLSVVLADRNYTVTGEEPHVQL 955

Query: 2027 SVKSSSIYSIVNIKI----GVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMM 2082
             V   ++  +V+I I     + + ++ +  + I I       +CG+CGNFN   +D+   
Sbjct: 956  GVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFET 1015

Query: 2083 PSDEVANSDSEFVNSWKDKDIDPSC--QSLLVDEQQIPAEQQENPSGNCRAADLRR--AR 2138
             S  VA+S+ E VNSWK+    P C   S + D               C     RR  A 
Sbjct: 1016 RSRYVASSELELVNSWKE---SPLCGDVSFVTDP--------------CSLNAFRRSWAE 1058

Query: 2139 EKCEAALRAPVWAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGL 2196
             KC + + +  +A C S++   P+   C      C+ GG  + LC A+ A+   C  +G+
Sbjct: 1059 RKC-SVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGV 1117

Query: 2197 KPPLWRNSSFCPLECPAYSSYT 2218
                WR  +FCP+ C  Y+++T
Sbjct: 1118 CVD-WRTPAFCPIYCGFYNTHT 1138



 Score =  111 bits (278), Expect = 8e-24
 Identities = 153/595 (25%), Positives = 208/595 (34%), Gaps = 106/595 (17%)

Query: 533  TCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPT 592
            T P     ELP  +   +TGP  T   T  PT  T +P            +PT P    T
Sbjct: 1342 TLPKSTNQELPGTTATQTTGPRPTPASTTGPT--TPQP-----------GQPTRPTATET 1388

Query: 593  IPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTE------KPTIPSEKPTIPSEK 646
              T   T  T  P  P    + P+    +PS  P   T        PT    + T+P+  
Sbjct: 1389 TQTRTTTEYT-TPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHV 1447

Query: 647  PTISTEKPTVPTEEPTTPTE-ETTTSMEEPVIPT----------EKPSIPTEKPSIPTEK 695
            P  ST   T  T    TPT  +  TS      PT             S  T  P  PT  
Sbjct: 1448 PPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTS 1507

Query: 696  PTISMEETIISTEKPTISPEKPTIPTEKPTI-PTEKSTISPEKPTTPTEKPTIPTEKPTI 754
             T S   +  ST K   S    T  T  P + PT  +TI+P   +T T  P   T   T 
Sbjct: 1508 GT-SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566

Query: 755  SPEKPTTPTEKP---------------TISPEKLTIPT---EKPTIPTEKPTIPTEKPTI 796
            S   P   T  P               T      T PT    + T+PT  P   T   T 
Sbjct: 1567 SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 1626

Query: 797  STEEPTTPTE-ETTISTEKPSIPM----------------EKPTLPTEETTTSVEETTIS 839
            ST    TPT  +   S    S+P                   PT+    + TS   ++++
Sbjct: 1627 STHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLN 1686

Query: 840  TEKLTIPMEKPTIST-EKPTIPTEKPTISPEKLTIPTEKLTIPT-----EKPTIPIEETT 893
            T K +  +   T ST       T    I+P   +  T  +T+ T      + +    +T+
Sbjct: 1687 TAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTS 1746

Query: 894  ISTEKLTIPTEKP--------TISPEKPTISTEKPTIPTEKPT---IPTEETTISTEKLT 942
             S    T  T  P        +I+P   +  T  P   T   T   +PT  TT S    T
Sbjct: 1747 TSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGT 1806

Query: 943  IP---------------TEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPT 987
             P               T  PT S    T+PT  P+ ST   T  T  + IPT      +
Sbjct: 1807 TPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATS 1866

Query: 988  EK-PTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
                ++PT  +    PP  +  ATG +     P  P+T  TS    + +T+++ST
Sbjct: 1867 ASIHSMPTGTI----PPPTTIKATG-STHTAPPMTPTTSGTSQSPSSFSTAKTST 1916



 Score =  107 bits (266), Expect = 2e-22
 Identities = 142/565 (25%), Positives = 195/565 (34%), Gaps = 43/565 (7%)

Query: 544  PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE 603
            P  P ++  P  T+GL   P  +T + T +  KP+VT           +  T     ST 
Sbjct: 1271 PPRPTTAVTPQATSGL---PPTATLRSTAT--KPTVTQATTRATASTASPATTSTAQSTT 1325

Query: 604  KPTIPSEKPNMPSEKPTIPS----EKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659
            + T+    P      PT+P     E P     + T P   P   +   T    +PT PT 
Sbjct: 1326 RTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTA 1385

Query: 660  EPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTI 719
              TT T  TTT    P  P    S PT    +P+  P ++      +T  PT S  + T+
Sbjct: 1386 TETTQTR-TTTEYTTPQTPHTTHSPPTAGSPVPSTGP-VTATSFHATTTYPTPSHPETTL 1443

Query: 720  PTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEK 779
            PT  P   T   T S     TPT      +     +   PT     PT      +  T  
Sbjct: 1444 PTHVPPFSTSLVTPSTHTVITPTHAQMATSAS---NHSAPTGTIPPPTTLKATGSTHTAP 1500

Query: 780  PTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSI-PMEKPTLPTEETTTSVEETTI 838
            P  PT   T      + ST +  T     T ST  P + P    T+    T+T       
Sbjct: 1501 PITPTTSGTSQAHS-SFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVA 1559

Query: 839  STEKLTIPMEKPTISTEKPTIPT-EKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTE 897
             T   T     P  +T  P  PT   P  S   +T  + K T     P+ P  +TT+ T 
Sbjct: 1560 HTNSATSSRPPPPFTTHSP--PTGSSPFSSTGPMTATSFKTTTTYPTPSHP--QTTLPTH 1615

Query: 898  ------KLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKL-TIPTEKPTI 950
                   L  P+    I+P    ++T          TIP   T  +T    T PT   T 
Sbjct: 1616 VPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTT 1675

Query: 951  S----------PEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKP-TIPTEKLTA 999
            S            K +      T ST      +   T  T  PT     P T+ T   + 
Sbjct: 1676 SGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQ 1735

Query: 1000 LRPPHPSP-TATGLAALVMSPHAP---STPMTSVILGTTTTSRSSTERCPPNARYESCAC 1055
             R    +  T+T L +   S H P   ST  TS+    T+T   +      +A       
Sbjct: 1736 SRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795

Query: 1056 PASCKSPRPSCGPLCREGCVCNPGF 1080
            P +  SP     P+   G V    F
Sbjct: 1796 PFTTHSPPTGTTPISSTGPVTATSF 1820



 Score = 96.7 bits (239), Expect = 3e-19
 Identities = 139/588 (23%), Positives = 221/588 (37%), Gaps = 100/588 (17%)

Query: 2097 SWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASR 2156
            S+  +  + +C SL   ++         P   C   D     +K E   +A    QC   
Sbjct: 671  SYNSQACERTCLSL--SDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKA----QCPCI 724

Query: 2157 IDLTPFLVDCANTL-------CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPL 2209
            ++   F++   +T+       C  G L  +  Q  Q F A+CQ+    P  +++ S    
Sbjct: 725  LEGYKFILAEQSTVINGITCHCINGRL--SCPQRPQMFLASCQA----PKTFKSCS---- 774

Query: 2210 ECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPG-YVLSEDKCVPRSQCG 2268
                 SS      +C+P+C  L      A VP+ C  GC+C  G Y  ++ +CVP  +C 
Sbjct: 775  ----QSSENKFGAACAPTCQMLATGV--ACVPTKCEPGCVCAEGLYENADGQCVPPEECP 828

Query: 2269 CKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKS 2328
            C+ + G S P G + + + C   C C+ G      + C  G+HC  T             
Sbjct: 829  CEFS-GVSYP-GGAELHTDC-RTCSCSRGR-----WACQQGTHCPST------------- 867

Query: 2329 EQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFL 2388
              C++YG+   +TFDG  +   G   Y+L   V  + +      +   N        I  
Sbjct: 868  --CTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTEN-------VICG 918

Query: 2389 QEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTD------FEL 2442
               +T     K+ L  GL +V+ ++   V      H+++ +    L LV D      + L
Sbjct: 919  NSGVTCSRAIKIFL-GGLSVVLADRNYTVT-GEEPHVQLGVTPGALSLVVDISIPGRYNL 976

Query: 2443 VVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTE 2502
             + +      +I +    +  + GLCGN++ N K+D    S  +  +     NSW     
Sbjct: 977  TLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSW----- 1031

Query: 2503 DALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL-ASNSTQACRVLADPQGPFAACH 2561
                        +E     ++   T      CS      S + + C V+      FA CH
Sbjct: 1032 ------------KESPLCGDVSFVT----DPCSLNAFRRSWAERKCSVINSQ--TFATCH 1073

Query: 2562 QTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
              V   P+ E CV D C      + E L C  ++ YA  C + G  +  WR    C   C
Sbjct: 1074 SKVYHLPYYEACVRDACGCDSGGDCECL-CDAVAAYAQACLDKGVCV-DWRTPAFCPIYC 1131

Query: 2622 -LQNPCQNDGQCREQGATFTCECEVGYGGGLCMEPRDAPPPRKPASNL 2668
               N    DG   E   T    C   Y   LC     + P   P SN+
Sbjct: 1132 GFYNTHTQDGH-GEYQYTQEANCTWHYQPCLC----PSQPQSVPGSNI 1174



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 142/547 (25%), Positives = 187/547 (34%), Gaps = 58/547 (10%)

Query: 540  PELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPT 599
            PE+ P S  + T P+ T+  T  P   T   T S   P  TT  P      P   T   T
Sbjct: 1535 PEVTPTSTTTIT-PNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSS-PFSSTGPMT 1592

Query: 600  ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEK-----P 654
             ++ K T     P+ P  + T+P+  P   T   T PS    I      ++T       P
Sbjct: 1593 ATSFKTTTTYPTPSHP--QTTLPTHVPPFSTSLVT-PSTHTVITPTHAQMATSASIHSMP 1649

Query: 655  TVPTEEPTT----------PTEETTTSMEEPVIP---TEKPSIPTEKPSIPTEKPTISME 701
            T     PTT          PT   TTS     +    T K S      +  T     +  
Sbjct: 1650 TGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATST 1709

Query: 702  ETIISTEKPTISPEKPTIPTEKPT------IPTEKSTISPEKPTTPTEKPTIPTEKPT-I 754
             T   T  PT +   P   T   T        T K++ S    T+ T  P + +   T I
Sbjct: 1710 STTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSI 1769

Query: 755  SPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE-ETTISTE 813
            +P   +T T  P       T         T  P  PT    IS+  P T T  +TT +  
Sbjct: 1770 TPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSP--PTGTTPISSTGPVTATSFQTTTTYP 1827

Query: 814  KPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK----PTIPTEKPTISPE 869
             PS P    TLPT   + S    T ST  + IP      ++      PT     PT    
Sbjct: 1828 TPSHP--HTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKA 1885

Query: 870  KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI 929
              +  T     PT   T     ++ ST K +      T S   P ++    T  T K T 
Sbjct: 1886 TGSTHTAPPMTPTTSGTSQ-SPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS 1944

Query: 930  PTEET----TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPT----- 980
                T    T S     +PT   T SP     PT     S+  P   T   T  T     
Sbjct: 1945 TGTRTPVAHTTSASSSRLPTPFTTHSP-----PTGSSPFSSTGPMTATSFQTTTTYPTPS 1999

Query: 981  -EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRS 1039
              + T+PT  P   T  +T   P   +   T    +  S    STP  +V   TT  +  
Sbjct: 2000 HPQTTLPTHVPPFSTSLVT---PSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056

Query: 1040 STERCPP 1046
            ST   PP
Sbjct: 2057 STHTAPP 2063



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 165/692 (23%), Positives = 237/692 (34%), Gaps = 141/692 (20%)

Query: 535  PVKVLPELPPV--SPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPT 592
            P       PP   +P+SSTGP   T                      TT  PT      T
Sbjct: 1794 PTPFTTHSPPTGTTPISSTGPVTATSF------------------QTTTTYPTPSHPHTT 1835

Query: 593  IPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTE 652
            +PT  P+ ST   T  +    +P+      S     +   PT     PT      +  T 
Sbjct: 1836 LPTHVPSFSTSLVTPSTHTVIIPTHTQMATSAS---IHSMPTGTIPPPTTIKATGSTHTA 1892

Query: 653  KPTVPTEEPTTP------TEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
             P  PT   T+       T +T+TS+      T  P +       PT    I+ + T   
Sbjct: 1893 PPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT------PTSTTNITPKHTSTG 1946

Query: 707  TEKP---TISPEKPTIPTEKPTI--PTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761
            T  P   T S     +PT   T   PT  S  S   P T T   T  T  PT S  + T 
Sbjct: 1947 TRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTY-PTPSHPQTTL 2005

Query: 762  PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSI--PM 819
            PT  P  S   +T P+    I T    + T     ST   T P   T  +T       PM
Sbjct: 2006 PTHVPPFSTSLVT-PSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPM 2064

Query: 820  EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPT---IPTEKPTIS----PEKLT 872
               T  T +T +S    T S+  ++     P  S+ +P    I T+ P +S    P   T
Sbjct: 2065 TVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTT 2124

Query: 873  --------------------IPTEKLTIPTEKPTI---------PIEETTISTEKLTIPT 903
                                +P+   +  T  P++         P+  TT+S+   +  +
Sbjct: 2125 NQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLS 2184

Query: 904  EKPTISP--EKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE-------- 953
              PT +     P   +      T + T+P   ++  T    +P    T+SP         
Sbjct: 2185 THPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASS 2244

Query: 954  --------KLTIPTEK-PTISTEKPTIPTEKLT--IPTEKPTIPTEKPT-IPTEKLTALR 1001
                    + T  T   P  S++  T  +  LT  +PT      T   T IPT  +T L 
Sbjct: 2245 TIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLT 2304

Query: 1002 PPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCK- 1060
              HP PT        +SP       T+  L ++ T+  ST   P +A   S   P     
Sbjct: 2305 TRHPGPT--------LSP-------TTRFLTSSLTAHGST---PASAPVSSLGTPTPTSP 2346

Query: 1061 ---SPRPSCGPLCREGCVCNPGFLFSDNHCIQASS-----------CNCFYNNDYYEPGA 1106
               S R     +  +GC+ N      +  CI A+S           C+C      YE   
Sbjct: 2347 GVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQL 2406

Query: 1107 EWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138
            E   P+ +      PG R+   + Q  +H VC
Sbjct: 2407 ELPCPDPST-----PGRRLVLTL-QVFSHCVC 2432



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 89/356 (25%), Positives = 136/356 (38%), Gaps = 36/356 (10%)

Query: 701  EETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPT 760
            EE +     P  +P+ PT P + PT  +  + + P   T+ T      T     S   P 
Sbjct: 1189 EEGVCVPCMPPTTPQPPTTP-QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPA 1247

Query: 761  TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPME 820
            +PT+ P +     T+ + KPT  + +P  PT   T        PT     +  KP++   
Sbjct: 1248 SPTQTPLLPA---TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQA 1304

Query: 821  KPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP--------------TEKPTI 866
                     + +   T  ST + T+ +  P  S   PT+P              T  P  
Sbjct: 1305 TTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRP 1364

Query: 867  SPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926
            +P   T PT      T +P  P   T   T +    TE  T  P+ P  +   PT  +  
Sbjct: 1365 TPASTTGPT------TPQPGQPTRPTATETTQTRTTTEYTT--PQTPHTTHSPPTAGSPV 1416

Query: 927  PTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTE-KPTI 985
            P+  T   T ++   T  T  PT S  + T+PT  P  ST   T  T  +  PT  +   
Sbjct: 1417 PS--TGPVTATSFHAT--TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMAT 1472

Query: 986  PTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
                 + PT  +    PP  +  ATG +     P  P+T  TS    + +T+++ T
Sbjct: 1473 SASNHSAPTGTI----PPPTTLKATG-STHTAPPITPTTSGTSQAHSSFSTNKTPT 1523



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 99/375 (26%), Positives = 141/375 (37%), Gaps = 53/375 (14%)

Query: 689  PSIPTEKPTISMEETIISTEKPTISPEKPT-IPTEKPTIPTEKSTISPEKPTT---PTEK 744
            PS P   P  ++E     ++      E+   +P   PT P   +T  P+ PTT   PT+ 
Sbjct: 1163 PSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPTTPQPPTT--PQLPTTGSRPTQV 1220

Query: 745  PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804
              +     TI     T P+     +P     PT+ P +P    T+ + KPT S+ EP  P
Sbjct: 1221 WPMTGTSTTIGLLSSTGPSPSSNHTPAS---PTQTPLLPA---TLTSSKPTASSGEPPRP 1274

Query: 805  TEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKP 864
            T   T        P     LP   T  S       T+  T    + T ST  P   +   
Sbjct: 1275 TTAVT--------PQATSGLPPTATLRSTATKPTVTQATT----RATASTASPATTSTAQ 1322

Query: 865  TISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPT 924
            + +   +T+PT   +     PT+P      + ++L   T   T  P     ST  PT P 
Sbjct: 1323 STTRTTMTLPTPATS--GTSPTLPKS----TNQELPGTTATQTTGPRPTPASTTGPTTPQ 1376

Query: 925  E-KPTIPTE----ETTISTEKLTIPTEKPTISPEKL--TIPTEKPTISTE------KPTI 971
              +PT PT     +T  +TE  T  T   T SP      +P+  P  +T        PT 
Sbjct: 1377 PGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTP 1436

Query: 972  PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVIL 1031
               + T+PT  P   T   T  T   T + P H        A +  S    S P  ++  
Sbjct: 1437 SHPETTLPTHVPPFSTSLVTPSTH--TVITPTH--------AQMATSASNHSAPTGTIPP 1486

Query: 1032 GTTTTSRSSTERCPP 1046
             TT  +  ST   PP
Sbjct: 1487 PTTLKATGSTHTAPP 1501



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 68/272 (25%), Positives = 102/272 (37%), Gaps = 29/272 (10%)

Query: 815  PSIPMEKPTLPTEET-TTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTI 873
            PS P   P    E     S +E     E + +P   PT  T +P    + PT        
Sbjct: 1163 PSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPT--TPQPPTTPQLPTTGSR---- 1216

Query: 874  PTEKLTIPTEKPTIPIEETT----ISTEKLTIPTEKP----TISPEKPTISTEKPTIPTE 925
            PT+   +     TI +  +T     S      PT+ P    T++  KPT S+ +P  PT 
Sbjct: 1217 PTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTT 1276

Query: 926  KPTIPTEETTISTEKLTIPTEKPTISPE--KLTIPTEKPTISTEKPTIPTEKLTIPTE-- 981
              T         T  L     KPT++    + T  T  P  ++   +     +T+PT   
Sbjct: 1277 AVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPAT 1336

Query: 982  ---KPTIP-TEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTS 1037
                PT+P +    +P    T    P P+P +T        P  P+ P  +    T TT+
Sbjct: 1337 SGTSPTLPKSTNQELPGTTATQTTGPRPTPAST-TGPTTPQPGQPTRPTATETTQTRTTT 1395

Query: 1038 RSSTERCPPNARYESCACPASCKSPRPSCGPL 1069
              +T + P          P +  SP PS GP+
Sbjct: 1396 EYTTPQTPHTTH-----SPPTAGSPVPSTGPV 1422


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score =  197 bits (502), Expect = 9e-50
 Identities = 163/515 (31%), Positives = 211/515 (40%), Gaps = 39/515 (7%)

Query: 450  VEFAYHMYGLGEGTMLELLLGS---PAG--SPPIPLWKRVGSQRPYWQNTSVTVPSGHQQ 504
            +E   ++ GLG      +  GS   P G  SP +  W +  +  P +   S +V SG   
Sbjct: 1484 MEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGAT--PAYGAWSPSVGSG--- 1538

Query: 505  PMQLIFKGIQG-SNTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENP 563
                +  G  G S +A+  A GF   +PG  P        P SP  S+    + G   +P
Sbjct: 1539 ----MTPGAAGFSPSAASDASGF---SPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSP 1591

Query: 564  TISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS 623
            + S   P      P   T         P  P+  PT  +  PT PS  P  P+  PT PS
Sbjct: 1592 SYSPTSPAYEPRSPGGYT---------PQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPS 1642

Query: 624  EKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPS 683
              PT  +  PT PS  PT PS  PT  +  PT P+  PT+P+   T+    P  P+  P+
Sbjct: 1643 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1702

Query: 684  IPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTE 743
             P+  P+ P+  PT         +  PT     PT P+  PT P+   T     PT+P  
Sbjct: 1703 SPSYSPTSPSYSPT-------SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNY 1755

Query: 744  KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
             PT P+  PT     PT+P   PT      T P+  PT P+  PT P+  P+     P +
Sbjct: 1756 TPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQS 1815

Query: 804  PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL-TIPMEKPTISTEKPTIPTE 862
            PT   +  +  PS P   PT P + T TS   +  S E   T P   PT     PT P  
Sbjct: 1816 PTYTPSSPSYSPSSPSYSPTSP-KYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKY 1874

Query: 863  KPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPT---ISPEKPTISTEK 919
             PT      T P    T PT  PT P+   T      T PT  PT    SP  PT S   
Sbjct: 1875 SPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTS 1934

Query: 920  PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEK 954
            P   T  PT P    T  T  LT P   P  S E+
Sbjct: 1935 PKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEE 1969



 Score =  184 bits (468), Expect = 8e-46
 Identities = 135/428 (31%), Positives = 173/428 (40%), Gaps = 41/428 (9%)

Query: 578  SVTTEKPTVP-KEKPTIPTEKPTISTE-KPTIPSEKPNMPSE-KPTIPSEKPTILTEKPT 634
            S T   P  P    P IP+    +S    PT P+ +P  P    P  PS  PT  +  PT
Sbjct: 1566 SPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPT 1625

Query: 635  IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTE 694
             PS  PT P+  PT  +  PT P+  PT+P+   T+    P  P+  P+ P+  P+ P+ 
Sbjct: 1626 SPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1685

Query: 695  KPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTI 754
             PT            P+ SP   T P+  PT P+   T     PT+P+  PT P+  PT 
Sbjct: 1686 SPT-----------SPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1731

Query: 755  SPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEK 814
                PT+P+  PT      T P   PT P+  PT P+  PT     PT+P    T  +  
Sbjct: 1732 PSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYS 1791

Query: 815  PSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIP 874
            P+ P   PT P+   ++                  P  + + PT     P+ SP     P
Sbjct: 1792 PTSPSYSPTSPSYSPSS------------------PRYTPQSPTYTPSSPSYSPSS---P 1830

Query: 875  TEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEET 934
            +   T P   PT P    +      T P   PT     PT     PT PT  PT P    
Sbjct: 1831 SYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSP 1890

Query: 935  TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP---TEKPTIPTEKPT 991
            T  T   T P   PT      T PT  PT     PT PT   T P   T  PT P   PT
Sbjct: 1891 TSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPT 1950

Query: 992  IPTEKLTA 999
             PT  LT+
Sbjct: 1951 SPTYSLTS 1958



 Score =  172 bits (436), Expect = 4e-42
 Identities = 127/408 (31%), Positives = 166/408 (40%), Gaps = 13/408 (3%)

Query: 622  PSEKPTILTEKPTIPSEKPTIPSEKPTISTE-KPTVPTEEPTTPTEETTTSMEEPVIPTE 680
            P+  PT  +     PS  P IPS    +S    PT P  EP +P   T      P  P+ 
Sbjct: 1563 PAWSPTPGSPGSPGPSS-PYIPSPGGAMSPSYSPTSPAYEPRSPGGYT------PQSPSY 1615

Query: 681  KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT 740
             P+ P+  P+ P+  PT         +  PT     PT P+  PT P+   T     PT+
Sbjct: 1616 SPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1675

Query: 741  PTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
            P+  PT P+  PT     PT+P+  PT      T P+  PT P+  PT P+  PT  +  
Sbjct: 1676 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1735

Query: 801  PTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP 860
            PT+P+   T     P+ P   PT P+   T+     T      T P   PT  +  PT P
Sbjct: 1736 PTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSP 1795

Query: 861  TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920
            +  PT      + P      PT  P+ P    +  +   T P   PT     P+     P
Sbjct: 1796 SYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTP 1855

Query: 921  TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPT 980
            T P   PT P    T      T PT  PT      T PT  PT     PT P    T PT
Sbjct: 1856 TSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPT 1915

Query: 981  EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTS 1028
              PT P   PT PT   T+ +    SPT+ G      SP +P+  +TS
Sbjct: 1916 YSPTSPKYSPTSPTYSPTSPKGSTYSPTSPG-----YSPTSPTYSLTS 1958



 Score =  122 bits (306), Expect = 5e-27
 Identities = 109/388 (28%), Positives = 152/388 (39%), Gaps = 35/388 (9%)

Query: 713  SPEKPTIP-TEKPTIPTEKSTISPE-KPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISP 770
            +P  P  P    P IP+    +SP   PT+P  +P  P            TP + P+ SP
Sbjct: 1568 TPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGY---------TP-QSPSYSP 1617

Query: 771  EKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETT 830
               T P+  PT P+  PT P   PT  +  PT+P+   T  +  P+ P   PT P+   T
Sbjct: 1618 ---TSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1674

Query: 831  TSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIE 890
            +     T  +   T P   PT  +  PT P+  PT      T P+   T P+  PT P  
Sbjct: 1675 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1734

Query: 891  ETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTI 950
              T  +   T P   PT     PT  +  PT P+  PT P    T      T P+  PT 
Sbjct: 1735 SPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTS 1794

Query: 951  SPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP--TEKLTALRPPHPSPT 1008
                 T P+  P+     P  PT   + P+  P+ P+  PT P  T    +  P  P  T
Sbjct: 1795 PSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYT 1854

Query: 1009 ATGLAALVMSP-HAPSTPM---TSVILGTTTTSRSSTE---------RCPPNARYESCAC 1055
             T       SP ++P++P    TS     TT   S T            P + +Y   + 
Sbjct: 1855 PTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSP 1914

Query: 1056 PASCKSPR-----PSCGPLCREGCVCNP 1078
              S  SP+     P+  P   +G   +P
Sbjct: 1915 TYSPTSPKYSPTSPTYSPTSPKGSTYSP 1942


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  192 bits (488), Expect = 4e-48
 Identities = 185/599 (30%), Positives = 249/599 (41%), Gaps = 86/599 (14%)

Query: 535  PVKVLPELPPVSPVSS----TGPSETTGLTENPTISTK-------------KPTVSIEKP 577
            P+   P LPP S  S     T   ETT  T+  T + K             K T SIEK 
Sbjct: 123  PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182

Query: 578  SVTTEKPTV-----PKEKPTIPTEKPTISTEK---PTIPSEKPNMPSEKPTIPSEKPTIL 629
            S     PT      P  K    T+ P ++T K   PT P E  +   ++PT     PT +
Sbjct: 183  SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT-----PTTI 237

Query: 630  TEKPTIPSEK-PTIPSEKPTISTEKPTVPTEEP--TTPTEETTTSMEEPVIPTEKPSIPT 686
               PT P E  PT     PT   E     T+EP  TTP E   T+ +EP   T K +  T
Sbjct: 238  KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 297

Query: 687  EKPSIPTEK----PTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPT 739
             K   PT      PT   E    + ++PT +  K   PT K   PT P E +  +P+KP 
Sbjct: 298  PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357

Query: 740  TPTEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST 798
                 PT P E    +P++P  T T++P+ +  K   PT   + PT   T     PT + 
Sbjct: 358  -----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTK 409

Query: 799  EEPTTPTEETTISTEKPSIPMEK---PTLPTEETTTSVEETTISTEKLTIP--MEKPTIS 853
              PTTP E +  +T++P+    K   PT P +   T+ +E   +T K   P   +KP  +
Sbjct: 410  SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469

Query: 854  TEK---PTIPTEKPTISPEKLTIPT-EKLTIPTEKPTIPIEETTISTEKL--TIPTEKPT 907
            T K   PT P E    +P+KLT  T EKL      PT P +    + E+L  T P E   
Sbjct: 470  TPKEPAPTTPKETAPTTPKKLTPTTPEKLA-----PTTPEKPAPTTPEELAPTTPEEPTP 524

Query: 908  ISPEKPTISTEK-----------PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956
             +PE+P  +T K           PT P E      +E   +T K T PT     +P  L 
Sbjct: 525  TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 584

Query: 957  IPT----EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT--EKLTALRPPHPSPTA- 1009
             P     +KP      PT   E  +   +KP   T K T PT  ++     P  P+PT  
Sbjct: 585  EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 644

Query: 1010 TGLAALVMSPHAPSTPMTSV---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
             G A   +   AP+TP       +  TTT   +ST    P         P + K P P+
Sbjct: 645  KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 703



 Score =  186 bits (471), Expect = 4e-46
 Identities = 180/569 (31%), Positives = 241/569 (42%), Gaps = 73/569 (12%)

Query: 535  PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
            P    P+ P  +P +   P+ TT     PT     PT   E  P+ T   PT PKE    
Sbjct: 208  PALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 265

Query: 594  PTEKPTISTEK-----------PTIPSEKPNMPSEKPTIPSEKPTILTEK---PTIPSEK 639
             T++P  +T K           PT     P  P E      +KP   T K   PT P E 
Sbjct: 266  TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325

Query: 640  -PTIPSEK-PTISTEKPTVPTEE---------PTTPTEETTTSMEEPVIPTEK-PSIPTE 687
             PT P E  PT     PT P E          PTTP E   T+ +EP   T K PS  T 
Sbjct: 326  TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 385

Query: 688  KPSIPT---EKPTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPTTP 741
            K   PT     PT + E    +T+    +P++P+  T K   PT P E +  +P+KP   
Sbjct: 386  KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-- 443

Query: 742  TEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
               PT P E    +P++P  T T+KP  +  K   PT      T K T PT    ++   
Sbjct: 444  ---PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT------TPKETAPTTPKKLT--- 491

Query: 801  PTTPTEETTISTEK--PSIPME-KPTLPTEETTTSVEETTISTEKLTIP--MEKPTISTE 855
            PTTP +    + EK  P+ P E  PT P E T T+ EE   +T K   P   ++P  +T 
Sbjct: 492  PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551

Query: 856  K---PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE-KPTISPE 911
            K   PT P E    +P++    T K T PT      ++E   +T K   P E  PT + E
Sbjct: 552  KEPAPTTPKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTKE 606

Query: 912  KPTISTEKPTIPTEKPTIPT--EETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
              + + +KP   T K T PT  +E   +T K   PT     +P  L    ++P  +T K 
Sbjct: 607  PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL----KEPAPTTPKK 662

Query: 970  TIPTEKLTIPTEKPTIPT-EKPTIPTEKLTA-LRPPHPSPTATGLAALVMSPHAPSTPMT 1027
              P E     T+ PT  T +KP   T K TA   P  P+PT T       +P  P    +
Sbjct: 663  PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTS 721

Query: 1028 SVILGTTTTSRSSTERCPPNARYESCACP 1056
             V   TTT   ++  + P  +  E  A P
Sbjct: 722  EVSTPTTTKEPTTIHKSPDESTPELSAEP 750



 Score =  166 bits (420), Expect = 3e-40
 Identities = 185/604 (30%), Positives = 251/604 (41%), Gaps = 101/604 (16%)

Query: 535  PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
            P    P+ P  +P ++  PS TT     PT +   PT + E  P+ T   PT PKE    
Sbjct: 364  PAPTTPKEP--APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 421

Query: 594  PTEKPTISTEK---PTIPSEK-PNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKPT 648
             T++P  +T K   PT P +  P  P E  PT P E     T+KP      PT P E P 
Sbjct: 422  TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-----PTTPKE-PA 475

Query: 649  ISTEKPTVPTEE----PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
             +T K T PT      PTTP +   T+ E+P      P+ P E      E+PT +  E  
Sbjct: 476  PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEP 530

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPE--KPTTPTE-KPTIP--TEKPTISPEKP 759
              T     +P  P  P   PT P E +  +P+   PTTP E  PT P  T   T+    P
Sbjct: 531  APTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 588

Query: 760  TTPTE------KPTISPEKLTIPTEKPTIPTEKPTIPT--EKPTISTEE---PTTP--TE 806
            TTP +       PT + E  +   +KP   T K T PT  ++P  +T +   PTTP  T 
Sbjct: 589  TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 648

Query: 807  ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPT--EKP 864
             TT+    P+ P  K   P E   T+ +  T +T       +KP  +T K T PT  ++P
Sbjct: 649  PTTLKEPAPTTP--KKPAPKELAPTTTKGPTSTTS------DKPAPTTPKETAPTTPKEP 700

Query: 865  TISPEKLTIPTEKLTIP-----TEKPTIPIEETTI------STEKLT------------- 900
              +  K   PT   T P        PT   E TTI      ST +L+             
Sbjct: 701  APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 760

Query: 901  ---IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT----IPTEKPTISPE 953
               +PT K T +  KP ++T      TE+    T ETT +  K+T      TEK T S  
Sbjct: 761  EPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-- 817

Query: 954  KLTIPTEKPTISTEKPTIPTEKLTIPTE--KPTIPTEKPTIPTEKLTALRPPH----PSP 1007
            K+T  T + T +T + T P +  T+ T    P + T K TI T ++  +  P     P  
Sbjct: 818  KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKD 875

Query: 1008 TATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCG 1067
             AT   A    P  P    T      T+T +  T   P   + ++   P    S  P   
Sbjct: 876  RATNSKATTPKPQKP----TKAPKKPTSTKKPKT--MPRVRKPKTTPTPRKMTSTMPELN 929

Query: 1068 PLCR 1071
            P  R
Sbjct: 930  PTSR 933



 Score =  147 bits (372), Expect = 1e-34
 Identities = 171/579 (29%), Positives = 227/579 (39%), Gaps = 95/579 (16%)

Query: 572  VSIEKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTIPSEK 625
            V   K + T +KPT    KP +  E  +           P   + + N  S  P I + K
Sbjct: 66   VKDNKKNRTKKKPT---PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 122

Query: 626  PTILTEKPTIPSEKPTIPSEKPTISTE-----KPTVPTEEPT-TPTEETTTSMEEP---- 675
            P  +  +P++P    T      T++ E     K T  T + T T  +E TTS +E     
Sbjct: 123  P--INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 180

Query: 676  --------------VIPTEKPSIPTEKPSIPTEK---PTISMEETIISTEKPTISPEK-- 716
                            PT K    T+ P++ T K   PT   E    + ++PT +  K  
Sbjct: 181  KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240

Query: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEK---PTIPTE---------KPTISPEKPTTPTE 764
            PT P E     T+ +  +P++P   T K   PT P E          PT +   PTTP E
Sbjct: 241  PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300

Query: 765  KPTISPEKLTIPTEK---PTIPTE-KPTIPTE-KPTISTEEPTTPTEETTISTEKPSIPM 819
                +P+K    T K   PT P E  PT P E  PT     PTTP E    + +KP+   
Sbjct: 301  PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA--- 357

Query: 820  EKPTLPTEETTTSVEE---TTISTEKLTIPME-KPTISTEKPTIPTE-KPTISPEKLTIP 874
              PT P E   T+ +E   TT      T P E  PT +   PT   E  PT +    T P
Sbjct: 358  --PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415

Query: 875  TEKLTIPTEK--PTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEK---PTIPTE-K 926
             E     T++  PT P E   TT      T P E    +P++P  +T K   PT P E  
Sbjct: 416  KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475

Query: 927  PTIPTEETTISTEKLTIPT---------EKPT-ISPEKL--TIPTEKPTISTEKPTIPTE 974
            PT P E    + +KLT  T         EKP   +PE+L  T P E    + E+P   T 
Sbjct: 476  PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 535

Query: 975  KLTIPT----EKPTIPTE-KPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSV 1029
            K   P       PT P E  PT P E            T  G A   +   AP+TP    
Sbjct: 536  KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 595

Query: 1030 ---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
               +  TTT   +ST    P         P + K P P+
Sbjct: 596  PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 634



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 42/219 (19%), Positives = 76/219 (34%), Gaps = 7/219 (3%)

Query: 492  QNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSST 551
            + T+ T     +  +      +  + T          +   T   KV      ++     
Sbjct: 805  KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 864

Query: 552  GPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEK 611
               E T   ++   ++K  T   +KP+   +KPT  K+  T+P  +   +T  PT     
Sbjct: 865  NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT--PTPRKMT 922

Query: 612  PNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTS 671
              MP   PT  S     + +  T P++ P   S+   ++ +       E  TP       
Sbjct: 923  STMPELNPT--SRIAEAMLQTTTRPNQTPN--SKLVEVNPKSEDAGGAEGETPHMLLRPH 978

Query: 672  MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710
            +  P +  +   +P          P +S +ET I   KP
Sbjct: 979  VFMPEVTPDMDYLPRVPNQGIIINPMLS-DETNICNGKP 1016


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  192 bits (488), Expect = 4e-48
 Identities = 185/599 (30%), Positives = 249/599 (41%), Gaps = 86/599 (14%)

Query: 535  PVKVLPELPPVSPVSS----TGPSETTGLTENPTISTK-------------KPTVSIEKP 577
            P+   P LPP S  S     T   ETT  T+  T + K             K T SIEK 
Sbjct: 164  PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223

Query: 578  SVTTEKPTV-----PKEKPTIPTEKPTISTEK---PTIPSEKPNMPSEKPTIPSEKPTIL 629
            S     PT      P  K    T+ P ++T K   PT P E  +   ++PT     PT +
Sbjct: 224  SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT-----PTTI 278

Query: 630  TEKPTIPSEK-PTIPSEKPTISTEKPTVPTEEP--TTPTEETTTSMEEPVIPTEKPSIPT 686
               PT P E  PT     PT   E     T+EP  TTP E   T+ +EP   T K +  T
Sbjct: 279  KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 338

Query: 687  EKPSIPTEK----PTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPT 739
             K   PT      PT   E    + ++PT +  K   PT K   PT P E +  +P+KP 
Sbjct: 339  PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398

Query: 740  TPTEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST 798
                 PT P E    +P++P  T T++P+ +  K   PT   + PT   T     PT + 
Sbjct: 399  -----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTK 450

Query: 799  EEPTTPTEETTISTEKPSIPMEK---PTLPTEETTTSVEETTISTEKLTIP--MEKPTIS 853
              PTTP E +  +T++P+    K   PT P +   T+ +E   +T K   P   +KP  +
Sbjct: 451  SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510

Query: 854  TEK---PTIPTEKPTISPEKLTIPT-EKLTIPTEKPTIPIEETTISTEKL--TIPTEKPT 907
            T K   PT P E    +P+KLT  T EKL      PT P +    + E+L  T P E   
Sbjct: 511  TPKEPAPTTPKETAPTTPKKLTPTTPEKLA-----PTTPEKPAPTTPEELAPTTPEEPTP 565

Query: 908  ISPEKPTISTEK-----------PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956
             +PE+P  +T K           PT P E      +E   +T K T PT     +P  L 
Sbjct: 566  TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 625

Query: 957  IPT----EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT--EKLTALRPPHPSPTA- 1009
             P     +KP      PT   E  +   +KP   T K T PT  ++     P  P+PT  
Sbjct: 626  EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 685

Query: 1010 TGLAALVMSPHAPSTPMTSV---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
             G A   +   AP+TP       +  TTT   +ST    P         P + K P P+
Sbjct: 686  KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 744



 Score =  186 bits (471), Expect = 4e-46
 Identities = 180/569 (31%), Positives = 241/569 (42%), Gaps = 73/569 (12%)

Query: 535  PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
            P    P+ P  +P +   P+ TT     PT     PT   E  P+ T   PT PKE    
Sbjct: 249  PALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 306

Query: 594  PTEKPTISTEK-----------PTIPSEKPNMPSEKPTIPSEKPTILTEK---PTIPSEK 639
             T++P  +T K           PT     P  P E      +KP   T K   PT P E 
Sbjct: 307  TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366

Query: 640  -PTIPSEK-PTISTEKPTVPTEE---------PTTPTEETTTSMEEPVIPTEK-PSIPTE 687
             PT P E  PT     PT P E          PTTP E   T+ +EP   T K PS  T 
Sbjct: 367  TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 426

Query: 688  KPSIPT---EKPTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPTTP 741
            K   PT     PT + E    +T+    +P++P+  T K   PT P E +  +P+KP   
Sbjct: 427  KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-- 484

Query: 742  TEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
               PT P E    +P++P  T T+KP  +  K   PT      T K T PT    ++   
Sbjct: 485  ---PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT------TPKETAPTTPKKLT--- 532

Query: 801  PTTPTEETTISTEK--PSIPME-KPTLPTEETTTSVEETTISTEKLTIP--MEKPTISTE 855
            PTTP +    + EK  P+ P E  PT P E T T+ EE   +T K   P   ++P  +T 
Sbjct: 533  PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592

Query: 856  K---PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE-KPTISPE 911
            K   PT P E    +P++    T K T PT      ++E   +T K   P E  PT + E
Sbjct: 593  KEPAPTTPKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTKE 647

Query: 912  KPTISTEKPTIPTEKPTIPT--EETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
              + + +KP   T K T PT  +E   +T K   PT     +P  L    ++P  +T K 
Sbjct: 648  PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL----KEPAPTTPKK 703

Query: 970  TIPTEKLTIPTEKPTIPT-EKPTIPTEKLTA-LRPPHPSPTATGLAALVMSPHAPSTPMT 1027
              P E     T+ PT  T +KP   T K TA   P  P+PT T       +P  P    +
Sbjct: 704  PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTS 762

Query: 1028 SVILGTTTTSRSSTERCPPNARYESCACP 1056
             V   TTT   ++  + P  +  E  A P
Sbjct: 763  EVSTPTTTKEPTTIHKSPDESTPELSAEP 791



 Score =  166 bits (420), Expect = 3e-40
 Identities = 185/604 (30%), Positives = 251/604 (41%), Gaps = 101/604 (16%)

Query: 535  PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
            P    P+ P  +P ++  PS TT     PT +   PT + E  P+ T   PT PKE    
Sbjct: 405  PAPTTPKEP--APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 462

Query: 594  PTEKPTISTEK---PTIPSEK-PNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKPT 648
             T++P  +T K   PT P +  P  P E  PT P E     T+KP      PT P E P 
Sbjct: 463  TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-----PTTPKE-PA 516

Query: 649  ISTEKPTVPTEE----PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
             +T K T PT      PTTP +   T+ E+P      P+ P E      E+PT +  E  
Sbjct: 517  PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEP 571

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPE--KPTTPTE-KPTIP--TEKPTISPEKP 759
              T     +P  P  P   PT P E +  +P+   PTTP E  PT P  T   T+    P
Sbjct: 572  APTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 629

Query: 760  TTPTE------KPTISPEKLTIPTEKPTIPTEKPTIPT--EKPTISTEE---PTTP--TE 806
            TTP +       PT + E  +   +KP   T K T PT  ++P  +T +   PTTP  T 
Sbjct: 630  TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 689

Query: 807  ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPT--EKP 864
             TT+    P+ P  K   P E   T+ +  T +T       +KP  +T K T PT  ++P
Sbjct: 690  PTTLKEPAPTTP--KKPAPKELAPTTTKGPTSTTS------DKPAPTTPKETAPTTPKEP 741

Query: 865  TISPEKLTIPTEKLTIP-----TEKPTIPIEETTI------STEKLT------------- 900
              +  K   PT   T P        PT   E TTI      ST +L+             
Sbjct: 742  APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 801

Query: 901  ---IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT----IPTEKPTISPE 953
               +PT K T +  KP ++T      TE+    T ETT +  K+T      TEK T S  
Sbjct: 802  EPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-- 858

Query: 954  KLTIPTEKPTISTEKPTIPTEKLTIPTE--KPTIPTEKPTIPTEKLTALRPPH----PSP 1007
            K+T  T + T +T + T P +  T+ T    P + T K TI T ++  +  P     P  
Sbjct: 859  KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKD 916

Query: 1008 TATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCG 1067
             AT   A    P  P    T      T+T +  T   P   + ++   P    S  P   
Sbjct: 917  RATNSKATTPKPQKP----TKAPKKPTSTKKPKT--MPRVRKPKTTPTPRKMTSTMPELN 970

Query: 1068 PLCR 1071
            P  R
Sbjct: 971  PTSR 974



 Score =  147 bits (372), Expect = 1e-34
 Identities = 171/579 (29%), Positives = 227/579 (39%), Gaps = 95/579 (16%)

Query: 572  VSIEKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTIPSEK 625
            V   K + T +KPT    KP +  E  +           P   + + N  S  P I + K
Sbjct: 107  VKDNKKNRTKKKPT---PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 163

Query: 626  PTILTEKPTIPSEKPTIPSEKPTISTE-----KPTVPTEEPT-TPTEETTTSMEEP---- 675
            P  +  +P++P    T      T++ E     K T  T + T T  +E TTS +E     
Sbjct: 164  P--INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 221

Query: 676  --------------VIPTEKPSIPTEKPSIPTEK---PTISMEETIISTEKPTISPEK-- 716
                            PT K    T+ P++ T K   PT   E    + ++PT +  K  
Sbjct: 222  KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281

Query: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEK---PTIPTE---------KPTISPEKPTTPTE 764
            PT P E     T+ +  +P++P   T K   PT P E          PT +   PTTP E
Sbjct: 282  PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341

Query: 765  KPTISPEKLTIPTEK---PTIPTE-KPTIPTE-KPTISTEEPTTPTEETTISTEKPSIPM 819
                +P+K    T K   PT P E  PT P E  PT     PTTP E    + +KP+   
Sbjct: 342  PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA--- 398

Query: 820  EKPTLPTEETTTSVEE---TTISTEKLTIPME-KPTISTEKPTIPTE-KPTISPEKLTIP 874
              PT P E   T+ +E   TT      T P E  PT +   PT   E  PT +    T P
Sbjct: 399  --PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456

Query: 875  TEKLTIPTEK--PTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEK---PTIPTE-K 926
             E     T++  PT P E   TT      T P E    +P++P  +T K   PT P E  
Sbjct: 457  KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516

Query: 927  PTIPTEETTISTEKLTIPT---------EKPT-ISPEKL--TIPTEKPTISTEKPTIPTE 974
            PT P E    + +KLT  T         EKP   +PE+L  T P E    + E+P   T 
Sbjct: 517  PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 576

Query: 975  KLTIPT----EKPTIPTE-KPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSV 1029
            K   P       PT P E  PT P E            T  G A   +   AP+TP    
Sbjct: 577  KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 636

Query: 1030 ---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
               +  TTT   +ST    P         P + K P P+
Sbjct: 637  PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 675



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 42/219 (19%), Positives = 76/219 (34%), Gaps = 7/219 (3%)

Query: 492  QNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSST 551
            + T+ T     +  +      +  + T          +   T   KV      ++     
Sbjct: 846  KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 905

Query: 552  GPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEK 611
               E T   ++   ++K  T   +KP+   +KPT  K+  T+P  +   +T  PT     
Sbjct: 906  NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT--PTPRKMT 963

Query: 612  PNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTS 671
              MP   PT  S     + +  T P++ P   S+   ++ +       E  TP       
Sbjct: 964  STMPELNPT--SRIAEAMLQTTTRPNQTPN--SKLVEVNPKSEDAGGAEGETPHMLLRPH 1019

Query: 672  MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710
            +  P +  +   +P          P +S +ET I   KP
Sbjct: 1020 VFMPEVTPDMDYLPRVPNQGIIINPMLS-DETNICNGKP 1057


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  192 bits (488), Expect = 4e-48
 Identities = 185/599 (30%), Positives = 249/599 (41%), Gaps = 86/599 (14%)

Query: 535  PVKVLPELPPVSPVSS----TGPSETTGLTENPTISTK-------------KPTVSIEKP 577
            P+   P LPP S  S     T   ETT  T+  T + K             K T SIEK 
Sbjct: 216  PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 275

Query: 578  SVTTEKPTV-----PKEKPTIPTEKPTISTEK---PTIPSEKPNMPSEKPTIPSEKPTIL 629
            S     PT      P  K    T+ P ++T K   PT P E  +   ++PT     PT +
Sbjct: 276  SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT-----PTTI 330

Query: 630  TEKPTIPSEK-PTIPSEKPTISTEKPTVPTEEP--TTPTEETTTSMEEPVIPTEKPSIPT 686
               PT P E  PT     PT   E     T+EP  TTP E   T+ +EP   T K +  T
Sbjct: 331  KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 390

Query: 687  EKPSIPTEK----PTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPT 739
             K   PT      PT   E    + ++PT +  K   PT K   PT P E +  +P+KP 
Sbjct: 391  PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450

Query: 740  TPTEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST 798
                 PT P E    +P++P  T T++P+ +  K   PT   + PT   T     PT + 
Sbjct: 451  -----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTK 502

Query: 799  EEPTTPTEETTISTEKPSIPMEK---PTLPTEETTTSVEETTISTEKLTIP--MEKPTIS 853
              PTTP E +  +T++P+    K   PT P +   T+ +E   +T K   P   +KP  +
Sbjct: 503  SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 562

Query: 854  TEK---PTIPTEKPTISPEKLTIPT-EKLTIPTEKPTIPIEETTISTEKL--TIPTEKPT 907
            T K   PT P E    +P+KLT  T EKL      PT P +    + E+L  T P E   
Sbjct: 563  TPKEPAPTTPKETAPTTPKKLTPTTPEKLA-----PTTPEKPAPTTPEELAPTTPEEPTP 617

Query: 908  ISPEKPTISTEK-----------PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956
             +PE+P  +T K           PT P E      +E   +T K T PT     +P  L 
Sbjct: 618  TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 677

Query: 957  IPT----EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT--EKLTALRPPHPSPTA- 1009
             P     +KP      PT   E  +   +KP   T K T PT  ++     P  P+PT  
Sbjct: 678  EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 737

Query: 1010 TGLAALVMSPHAPSTPMTSV---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
             G A   +   AP+TP       +  TTT   +ST    P         P + K P P+
Sbjct: 738  KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 796



 Score =  186 bits (471), Expect = 4e-46
 Identities = 180/569 (31%), Positives = 241/569 (42%), Gaps = 73/569 (12%)

Query: 535  PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
            P    P+ P  +P +   P+ TT     PT     PT   E  P+ T   PT PKE    
Sbjct: 301  PALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 358

Query: 594  PTEKPTISTEK-----------PTIPSEKPNMPSEKPTIPSEKPTILTEK---PTIPSEK 639
             T++P  +T K           PT     P  P E      +KP   T K   PT P E 
Sbjct: 359  TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418

Query: 640  -PTIPSEK-PTISTEKPTVPTEE---------PTTPTEETTTSMEEPVIPTEK-PSIPTE 687
             PT P E  PT     PT P E          PTTP E   T+ +EP   T K PS  T 
Sbjct: 419  TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 478

Query: 688  KPSIPT---EKPTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPTTP 741
            K   PT     PT + E    +T+    +P++P+  T K   PT P E +  +P+KP   
Sbjct: 479  KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-- 536

Query: 742  TEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
               PT P E    +P++P  T T+KP  +  K   PT      T K T PT    ++   
Sbjct: 537  ---PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT------TPKETAPTTPKKLT--- 584

Query: 801  PTTPTEETTISTEK--PSIPME-KPTLPTEETTTSVEETTISTEKLTIP--MEKPTISTE 855
            PTTP +    + EK  P+ P E  PT P E T T+ EE   +T K   P   ++P  +T 
Sbjct: 585  PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644

Query: 856  K---PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE-KPTISPE 911
            K   PT P E    +P++    T K T PT      ++E   +T K   P E  PT + E
Sbjct: 645  KEPAPTTPKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTKE 699

Query: 912  KPTISTEKPTIPTEKPTIPT--EETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
              + + +KP   T K T PT  +E   +T K   PT     +P  L    ++P  +T K 
Sbjct: 700  PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL----KEPAPTTPKK 755

Query: 970  TIPTEKLTIPTEKPTIPT-EKPTIPTEKLTA-LRPPHPSPTATGLAALVMSPHAPSTPMT 1027
              P E     T+ PT  T +KP   T K TA   P  P+PT T       +P  P    +
Sbjct: 756  PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTS 814

Query: 1028 SVILGTTTTSRSSTERCPPNARYESCACP 1056
             V   TTT   ++  + P  +  E  A P
Sbjct: 815  EVSTPTTTKEPTTIHKSPDESTPELSAEP 843



 Score =  166 bits (420), Expect = 3e-40
 Identities = 185/604 (30%), Positives = 251/604 (41%), Gaps = 101/604 (16%)

Query: 535  PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
            P    P+ P  +P ++  PS TT     PT +   PT + E  P+ T   PT PKE    
Sbjct: 457  PAPTTPKEP--APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 514

Query: 594  PTEKPTISTEK---PTIPSEK-PNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKPT 648
             T++P  +T K   PT P +  P  P E  PT P E     T+KP      PT P E P 
Sbjct: 515  TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-----PTTPKE-PA 568

Query: 649  ISTEKPTVPTEE----PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
             +T K T PT      PTTP +   T+ E+P      P+ P E      E+PT +  E  
Sbjct: 569  PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEP 623

Query: 705  ISTEKPTISPEKPTIPTEKPTIPTEKSTISPE--KPTTPTE-KPTIP--TEKPTISPEKP 759
              T     +P  P  P   PT P E +  +P+   PTTP E  PT P  T   T+    P
Sbjct: 624  APTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 681

Query: 760  TTPTE------KPTISPEKLTIPTEKPTIPTEKPTIPT--EKPTISTEE---PTTP--TE 806
            TTP +       PT + E  +   +KP   T K T PT  ++P  +T +   PTTP  T 
Sbjct: 682  TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 741

Query: 807  ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPT--EKP 864
             TT+    P+ P  K   P E   T+ +  T +T       +KP  +T K T PT  ++P
Sbjct: 742  PTTLKEPAPTTP--KKPAPKELAPTTTKGPTSTTS------DKPAPTTPKETAPTTPKEP 793

Query: 865  TISPEKLTIPTEKLTIP-----TEKPTIPIEETTI------STEKLT------------- 900
              +  K   PT   T P        PT   E TTI      ST +L+             
Sbjct: 794  APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 853

Query: 901  ---IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT----IPTEKPTISPE 953
               +PT K T +  KP ++T      TE+    T ETT +  K+T      TEK T S  
Sbjct: 854  EPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-- 910

Query: 954  KLTIPTEKPTISTEKPTIPTEKLTIPTE--KPTIPTEKPTIPTEKLTALRPPH----PSP 1007
            K+T  T + T +T + T P +  T+ T    P + T K TI T ++  +  P     P  
Sbjct: 911  KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKD 968

Query: 1008 TATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCG 1067
             AT   A    P  P    T      T+T +  T   P   + ++   P    S  P   
Sbjct: 969  RATNSKATTPKPQKP----TKAPKKPTSTKKPKT--MPRVRKPKTTPTPRKMTSTMPELN 1022

Query: 1068 PLCR 1071
            P  R
Sbjct: 1023 PTSR 1026



 Score =  150 bits (378), Expect = 2e-35
 Identities = 173/583 (29%), Positives = 229/583 (39%), Gaps = 95/583 (16%)

Query: 568  KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTI 621
            KK  V   K + T +KPT    KP +  E  +           P   + + N  S  P I
Sbjct: 155  KKLKVKDNKKNRTKKKPT---PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 211

Query: 622  PSEKPTILTEKPTIPSEKPTIPSEKPTISTE-----KPTVPTEEPT-TPTEETTTSMEEP 675
             + KP  +  +P++P    T      T++ E     K T  T + T T  +E TTS +E 
Sbjct: 212  TTAKP--INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 269

Query: 676  ------------------VIPTEKPSIPTEKPSIPTEK---PTISMEETIISTEKPTISP 714
                                PT K    T+ P++ T K   PT   E    + ++PT + 
Sbjct: 270  QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 329

Query: 715  EK--PTIPTEKPTIPTEKSTISPEKPTTPTEK---PTIPTE---------KPTISPEKPT 760
             K  PT P E     T+ +  +P++P   T K   PT P E          PT +   PT
Sbjct: 330  IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 389

Query: 761  TPTEKPTISPEKLTIPTEK---PTIPTE-KPTIPTE-KPTISTEEPTTPTEETTISTEKP 815
            TP E    +P+K    T K   PT P E  PT P E  PT     PTTP E    + +KP
Sbjct: 390  TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 449

Query: 816  SIPMEKPTLPTEETTTSVEE---TTISTEKLTIPME-KPTISTEKPTIPTE-KPTISPEK 870
            +     PT P E   T+ +E   TT      T P E  PT +   PT   E  PT +   
Sbjct: 450  A-----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504

Query: 871  LTIPTEKLTIPTEK--PTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEK---PTIP 923
             T P E     T++  PT P E   TT      T P E    +P++P  +T K   PT P
Sbjct: 505  PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 564

Query: 924  TE-KPTIPTEETTISTEKLTIPT---------EKPT-ISPEKL--TIPTEKPTISTEKPT 970
             E  PT P E    + +KLT  T         EKP   +PE+L  T P E    + E+P 
Sbjct: 565  KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 624

Query: 971  IPTEKLTIPT----EKPTIPTE-KPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTP 1025
              T K   P       PT P E  PT P E            T  G A   +   AP+TP
Sbjct: 625  PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 684

Query: 1026 MTSV---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
                   +  TTT   +ST    P         P + K P P+
Sbjct: 685  KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 727



 Score =  105 bits (261), Expect = 8e-22
 Identities = 134/477 (28%), Positives = 195/477 (40%), Gaps = 61/477 (12%)

Query: 615  PSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIST-EKPTVPTEEPTTPTEETTTSME 673
            PS K   P    +   +  T  S KP  P++K T    E   +  E   +  +E+++S  
Sbjct: 73   PSSKKAPPPSGASQTIKSTTKRSPKP--PNKKKTKKVIESEEITEEHSVSENQESSSSSS 130

Query: 674  EPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKST- 732
                 +    I + K S    +    ++   +   K   + +KPT    KP +  E  + 
Sbjct: 131  SSSSSSTIRKIKSSKNSAANRELQKKLK---VKDNKKNRTKKKPT---PKPPVVDEAGSG 184

Query: 733  --------ISPEKPTTPTEK----PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780
                     +P+  TT   K    P I T KP I+P +P+ P    T     LT+  E  
Sbjct: 185  LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP-INP-RPSLPPNSDTSKETSLTVNKET- 241

Query: 781  TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
            T+ T++ T   ++ +   +E TT  +ET  S EK S     PT       T   ETT   
Sbjct: 242  TVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSAKDLAPTSKVLAKPTPKAETTTKG 300

Query: 841  EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL- 899
              LT P E PT     PT P E  + +P++ T  T K       PT P E    +T+   
Sbjct: 301  PALTTPKE-PT-----PTTPKEPASTTPKEPTPTTIK-----SAPTTPKEPAPTTTKSAP 349

Query: 900  TIPTEKPTISPEKPTISTEKPTIPT--EKPTIPTEETTISTEKLTIPT--EKPTISPEKL 955
            T P E    + ++P  +T K   PT  ++P   T ++  +T K   PT  +KP  +  K 
Sbjct: 350  TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409

Query: 956  TIPT--EKPTISTEKPTIPTEKLTIPTEK----PTIPTEK-PTIPTEKLTALRPPHPSPT 1008
              PT  ++PT +T K   PT K   PT      PT P +  PT P E      P  P+PT
Sbjct: 410  PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT-PKEPAPT 468

Query: 1009 ATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
             T       SP  P  P       TTT S  +T + P     +S   P + K P P+
Sbjct: 469  TTKEP----SPTTPKEPAP-----TTTKSAPTTTKEPAPTTTKS--APTTPKEPSPT 514



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 114/422 (27%), Positives = 163/422 (38%), Gaps = 55/422 (13%)

Query: 685  PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIP----TEKSTISPEKPTT 740
            PT  PS     P     +TI ST K   SP+ P     K  I     TE+ ++S  + ++
Sbjct: 69   PTSPPSSKKAPPPSGASQTIKSTTKR--SPKPPNKKKTKKVIESEEITEEHSVSENQESS 126

Query: 741  PTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTE- 799
             +   +  +   TI   K +  +       +KL +   K     +K   PT KP +  E 
Sbjct: 127  SSSSSS--SSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK---PTPKPPVVDEA 181

Query: 800  ---------EPTTPTEETT----------ISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
                     + TTP   TT          I+T KP  P  +P+LP    T+  +ET+++ 
Sbjct: 182  GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINP--RPSLPPNSDTS--KETSLTV 237

Query: 841  EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT-------IPIEETT 893
             K T    K T +T K T    K   +  K T   EK +     PT        P  ETT
Sbjct: 238  NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT 297

Query: 894  ISTEKLTIPTEKPTISPEKPTISTEKPTIPT---EKPTIPTEETTISTEKL-TIPTE-KP 948
                 LT P E    +P++P  +T K   PT     PT P E    +T+   T P E  P
Sbjct: 298  TKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 357

Query: 949  TISPEKLTIPTEKPTISTEKPTIPTEKLTIPT----EKPTIPTE-KPTIPTEKLTALRPP 1003
            T + E      ++P  +T K   PT   + PT      PT P +  PT P E      P 
Sbjct: 358  TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP-APTTPK 416

Query: 1004 HPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPR 1063
             P+PT     A      AP+TP           + ++ +   P    E    P + K P 
Sbjct: 417  EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE--PAPTTTKEPS 474

Query: 1064 PS 1065
            P+
Sbjct: 475  PT 476



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 42/219 (19%), Positives = 76/219 (34%), Gaps = 7/219 (3%)

Query: 492  QNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSST 551
            + T+ T     +  +      +  + T          +   T   KV      ++     
Sbjct: 898  KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 957

Query: 552  GPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEK 611
               E T   ++   ++K  T   +KP+   +KPT  K+  T+P  +   +T  PT     
Sbjct: 958  NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT--PTPRKMT 1015

Query: 612  PNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTS 671
              MP   PT  S     + +  T P++ P   S+   ++ +       E  TP       
Sbjct: 1016 STMPELNPT--SRIAEAMLQTTTRPNQTPN--SKLVEVNPKSEDAGGAEGETPHMLLRPH 1071

Query: 672  MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710
            +  P +  +   +P          P +S +ET I   KP
Sbjct: 1072 VFMPEVTPDMDYLPRVPNQGIIINPMLS-DETNICNGKP 1109


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 130,963,707
Number of Sequences: 37866
Number of extensions: 7604270
Number of successful extensions: 70145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 283
Number of HSP's successfully gapped in prelim test: 1233
Number of HSP's that attempted gapping in prelim test: 27292
Number of HSP's gapped (non-prelim): 14424
length of query: 2721
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2601
effective length of database: 13,703,598
effective search space: 35643058398
effective search space used: 35643058398
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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