BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens] (815 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens] 1625 0.0 gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),... 662 0.0 gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger)... 564 e-160 gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger)... 499 e-141 gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ... 488 e-138 gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens] 233 4e-61 gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),... 197 2e-50 gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger)... 191 2e-48 gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger), ... 190 4e-48 gi|14211919 solute carrier family 9, member 7 [Homo sapiens] 186 8e-47 gi|224465231 solute carrier family 9, member 11 [Homo sapiens] 56 1e-07 gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens] 55 3e-07 gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap... 39 0.025 gi|4505101 microtubule-associated protein 7 [Homo sapiens] 35 0.37 gi|75750492 phosphatidylinositol glycan, class W [Homo sapiens] 35 0.37 gi|223717983 solute carrier family 37 (glycerol-3-phosphate tran... 34 0.48 gi|38093649 solute carrier family 37 (glycerol-3-phosphate trans... 34 0.48 gi|71274109 nuclear factor of kappa light polypeptide gene enhan... 34 0.62 gi|117606370 UMP-CMP kinase 2 [Homo sapiens] 33 0.81 gi|33356148 formin-like 1 [Homo sapiens] 33 0.81 gi|150456444 hypothetical protein LOC57578 [Homo sapiens] 33 1.1 gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens] 32 2.4 gi|194097341 period 1 [Homo sapiens] 32 3.1 gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 32 3.1 gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 32 3.1 gi|117938768 GNAS complex locus alex [Homo sapiens] 32 3.1 gi|10835242 protein kinase, cGMP-dependent, type I isoform 2 [Ho... 31 4.0 gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens] 31 4.0 gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] 31 4.0 gi|197927160 solute carrier family 4, sodium bicarbonate cotrans... 31 5.3 >gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens] Length = 815 Score = 1625 bits (4207), Expect = 0.0 Identities = 815/815 (100%), Positives = 815/815 (100%) Query: 1 MVLRSGICGLSPHRIFPSLLVVVALVGLLPVLRSHGLQLSPTASTIRSSEPPRERSIGDV 60 MVLRSGICGLSPHRIFPSLLVVVALVGLLPVLRSHGLQLSPTASTIRSSEPPRERSIGDV Sbjct: 1 MVLRSGICGLSPHRIFPSLLVVVALVGLLPVLRSHGLQLSPTASTIRSSEPPRERSIGDV 60 Query: 61 TTAPPEVTPESRPVNHSVTDHGMKPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFH 120 TTAPPEVTPESRPVNHSVTDHGMKPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFH Sbjct: 61 TTAPPEVTPESRPVNHSVTDHGMKPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFH 120 Query: 121 VIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLR 180 VIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLR Sbjct: 121 VIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLR 180 Query: 181 QFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPV 240 QFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPV Sbjct: 181 QFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPV 240 Query: 241 AVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFFV 300 AVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFFV Sbjct: 241 AVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFFV 300 Query: 301 VALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASG 360 VALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASG Sbjct: 301 VALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASG 360 Query: 361 VVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLF 420 VVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLF Sbjct: 361 VVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLF 420 Query: 421 CLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLF 480 CLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLF Sbjct: 421 CLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLF 480 Query: 481 LTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGH 540 LTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGH Sbjct: 481 LTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGH 540 Query: 541 YGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSA 600 YGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSA Sbjct: 541 YGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSA 600 Query: 601 VSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYE 660 VSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYE Sbjct: 601 VSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYE 660 Query: 661 EAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITID 720 EAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITID Sbjct: 661 EAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITID 720 Query: 721 PASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTP 780 PASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTP Sbjct: 721 PASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTP 780 Query: 781 APSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ 815 APSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ Sbjct: 781 APSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ 815 >gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger), member 2 [Homo sapiens] Length = 812 Score = 662 bits (1707), Expect = 0.0 Identities = 368/771 (47%), Positives = 500/771 (64%), Gaps = 53/771 (6%) Query: 68 TPESRPVNHSVTDHG--MKPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFHVIPTI 125 T S P SV G + PV +DY HV+ PFEI+LWILLA L KIGFH+ + Sbjct: 45 TSSSPPSPASVVAPGTTLFEESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKL 104 Query: 126 SSIVPESCLLIVVGLLVGGLIKGVGE-TPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTE 184 +IVPESCLLI+VGLL+GG+I GV E +PP +++DVFFL+LLPPI+LDAGYF+P R F E Sbjct: 105 PTIVPESCLLIMVGLLLGGIIFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFE 164 Query: 185 NLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLA 244 N+GTI +AVVGTLWN+ +G ++ +C + +++I LL NLLFGS+ISAVDPVAVLA Sbjct: 165 NIGTIFWYAVVGTLWNSIGIGVSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLA 224 Query: 245 VFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFFVVALG 304 VFE IH+NE L+ILVFGESLLNDAVTVVLY+LF+ F + + +D+F G +FFVV +G Sbjct: 225 VFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCQMKTIETIDVFAGIANFFVVGIG 284 Query: 305 GVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMR 364 GVL+G+ G IAAFT+RFT +IRVIEPLFVFLYSY++Y++AE+FHLSGIMA+ A + M Sbjct: 285 GVLIGIFLGFIAAFTTRFTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMN 344 Query: 365 PYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIA 424 YVE N+S KS+TTIKYF+KM SSVSETLIFIF+GVSTV +H WNW FV TL FCL+ Sbjct: 345 KYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCLMW 404 Query: 425 RVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAI 484 R LGV LT IN+FR + LT KDQFIIAYGGLRGAI F+L +LL FP LF+TA Sbjct: 405 RALGVFVLTQVINRFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAA 464 Query: 485 ITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHH 544 I VIFFTVF+ G+TIRPLV+ L VK+ + +++++EEI+ + DH+ TGIED+CGH+GH+ Sbjct: 465 IVVIFFTVFILGITIRPLVEFLDVKRSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHN 524 Query: 545 HWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTV 604 W+DK +F+ KY++K LI E + +++ Y K+E+K AIE+ E+G + +P+ S Sbjct: 525 FWRDKFKKFDDKYLRKLLIR-ENQPKSSIVSLYKKLEIKHAIEMAETGMISTVPTFASLN 583 Query: 605 SMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWN 664 + E + ++ + +EIR++L NL + RQR SYNRH+L AD E Sbjct: 584 DCR---------EEKIRKVTSSETDEIRELLSRNLYQIRQRTLSYNRHSLTADTSERQAK 634 Query: 665 QMLLRRQ--------------KARQLEQKINNYLTVPAH-KLDSPTMSRARIG-SDPLAY 708 ++L+RR+ + + + YL++P + KL R I +D + Sbjct: 635 EILIRRRHSLRESIRKDSSLNREHRASTSTSRYLSLPKNTKLPEKLQKRRTISIADGNSS 694 Query: 709 EPKED--LPVITIDPA---------SPQSPESVDLVNEELKGKV-LGLSRD-----PAKV 751 + D V+ + P S +SP+S + E K +V + RD P Sbjct: 695 DSDADAGTTVLNLQPRARRFLPEQFSKKSPQSYKM---EWKNEVDVDSGRDMPSTPPTPH 751 Query: 752 AEEDEDDDGGIMMR---SKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPG 799 + E G++ + SK+ S +D T P + + R S+PG Sbjct: 752 SREKGTQTSGLLQQPLLSKDQSGSEREDSLTEGIPPKPPPRLVWRA-SEPG 801 >gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger), member 4 [Homo sapiens] Length = 798 Score = 564 bits (1453), Expect = e-160 Identities = 289/592 (48%), Positives = 403/592 (68%), Gaps = 15/592 (2%) Query: 84 KPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVG 143 +P + V +DY +V+ P+E++LWILLA L KIGFH+ + ++PESCLLI+VG LVG Sbjct: 52 EPEEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVG 111 Query: 144 GLIKGVG-ETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAF 202 G+I G ++PP + S ++FL+LLPPI+L+ GYF+P R F EN+G+IL +AV+G L NA Sbjct: 112 GIIFGTDHKSPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINAL 171 Query: 203 FLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGE 262 +G +Y +C V + ++ LL NLLFGS+ISAVDPVAVLAVFEE +NE L++++FGE Sbjct: 172 GIGLSLYLICQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGE 231 Query: 263 SLLNDAVTVVLYHL---FEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFT 319 +LLND +TVVLY++ F + +E + VDI G F VV LGGVL G+V+G I+AF Sbjct: 232 ALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFI 291 Query: 320 SRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTI 379 +RFT +I IEPL VF++SY++YL+AE +LSGI+A+ A V M+ YVE N+S S+TTI Sbjct: 292 TRFTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTI 351 Query: 380 KYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKF 439 KYF+KM SSVSETLIFIF+GVSTV +H WNW F+ TL FC I R + V L + N+F Sbjct: 352 KYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQF 411 Query: 440 RIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTI 499 R + KDQ II Y G+RGA +FSL +LL FP +F+TA + VI+FTVF+QG+T+ Sbjct: 412 RTFPFSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITV 471 Query: 500 RPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVK 559 PLV L VKK + K SINEE+H + +DHL GIED+CGH+ H+ +DK +F+ +Y++ Sbjct: 472 GPLVRYLDVKKTNK-KESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLR 530 Query: 560 KCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERI 619 K LI K +++ Y K+EMKQAIE+VE+G + ++ P + Sbjct: 531 KILIRKNLPKS-SIVSLYKKLEMKQAIEMVETGILSSTAFSI---------PHQAQRIQG 580 Query: 620 LPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQ 671 + LS + E IR IL +N+ + RQR SYN++ L E+ ++L+RRQ Sbjct: 581 IKRLSPEDVESIRDILTSNMYQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQ 632 >gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 [Homo sapiens] Length = 834 Score = 499 bits (1285), Expect = e-141 Identities = 299/731 (40%), Positives = 440/731 (60%), Gaps = 50/731 (6%) Query: 89 FPVLGIDYTHVRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKG 148 F V+ ++ HV+ P+ I+LWIL+A L KIGFH+ ++S+VPES LLIV+GL++GG++ Sbjct: 42 FQVVTFEWAHVQDPYVIALWILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVWA 101 Query: 149 VGETPPF-LQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGL 207 F L VFF +LLPPI+LDAGYF+P R F NLGTIL++AVVGT+WNA G Sbjct: 102 ADHIASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLS 161 Query: 208 MYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLND 267 +Y V L G IGLLD LLFGS+++AVDPVAVLAVFEE+H+NE+L I+VFGESLLND Sbjct: 162 LYGVFLSGLMGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLND 221 Query: 268 AVTVVLYHLFEEFA--NYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSH 325 AVTVVLY++FE F ++V VD G +SFFVV+LGG LVGVV+ + + +RFT H Sbjct: 222 AVTVVLYNVFESFVALGGDNVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKH 281 Query: 326 IRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKM 385 +R+IEP FVF+ SY++YL++E+ LS I+A+ G+ + YV+ANIS +S TT++Y +KM Sbjct: 282 VRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKM 341 Query: 386 WSSVSETLIFIFLGVSTV-AGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKL 444 +S +ET+IF+FLG+S V WN FV+ TL+F + R +GV+ TW +N++R+V+L Sbjct: 342 LASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQL 401 Query: 445 TPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVD 504 P DQ +++YGGLRGA+AF+L LLD +LF++ I V+FFTV QG+TI+PLV Sbjct: 402 EPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQ 461 Query: 505 LLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIA 564 L VK+ + + +NE++H + DH+L+ IEDI G GH++ +DK + F++K++ + L+ Sbjct: 462 WLKVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMR 521 Query: 565 GERSK-EPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNI-----HPKSLPSER 618 K +++ +H++ +K AI V G + + + S N+ P+S E Sbjct: 522 RSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEA 581 Query: 619 ILPALSKDK-----------EEEIRKI-----------LRNNLQKTRQRLRS-YNRHTLV 655 + L ++ E+ R I L+ L K RQ + Y+RH L Sbjct: 582 SVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELT 641 Query: 656 ADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLP 715 +E ++ + R ++LE + L + +K + R R + P LP Sbjct: 642 PTE-DEKQDREIFHRTMRKRLESFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLP 700 Query: 716 VITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTD 775 + +SP N +K K L LS D + DE+ GGI + T +D Sbjct: 701 M--------ESPAQ----NFTIKEKDLELS-DTEEPPNYDEEMSGGIEFLASVTKDTASD 747 Query: 776 DVFTPAPSDSP 786 +PA D+P Sbjct: 748 ---SPAGIDNP 755 >gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), isoform 5 [Homo sapiens] Length = 896 Score = 488 bits (1256), Expect = e-138 Identities = 272/602 (45%), Positives = 387/602 (64%), Gaps = 27/602 (4%) Query: 99 VRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPF-LQ 157 V P+ ++LWIL+A L KI FH+ ++S+VPESCLLI++GL++GG++ V + + L+ Sbjct: 44 VEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLE 103 Query: 158 SDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGE 217 FFLFLLPPI+LD+GYF+P R F +NLG IL +AVVGTLWNAF G ++ + G Sbjct: 104 PGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLV 163 Query: 218 QIN-NIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHL 276 GLLD LLFGS+ISAVDPVAVLAVFEE+H+NE L I+VFGESLLNDAVTVVLY + Sbjct: 164 APRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKV 223 Query: 277 FEEFANY--EHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFV 334 F +V D G S FVV+LGG VG+V+ + A T+RFT +R+IEPL V Sbjct: 224 CNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLV 283 Query: 335 FLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSVSETLI 394 FL +Y AYL+AE+ LS I+A+ G+ + YVEANISHKS TT+KY +K +S +ET+I Sbjct: 284 FLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVI 343 Query: 395 FIFLGVSTVAGSHHWNWT--FVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFII 452 F+ LG+S V S W W V+ TL+F L R LGV+ TW +N+FR+V L DQ ++ Sbjct: 344 FMLLGISAVDSSK-WAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVM 402 Query: 453 AYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQ 512 +YGGLRGA+AF+L LLD+ P D F+ I V+FFTV VQG+TI+PLV L VK+ + Sbjct: 403 SYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSE 462 Query: 513 ETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSK-EP 571 K ++N+E+H DH+L +ED+ GH+G+H+W+D+ +F+KKY+ + L+ + Sbjct: 463 HHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRD 522 Query: 572 QLIAFYHKMEMKQAIELVESGG---------MGKIPS--AVSTVSMQNIHPKS-----LP 615 Q+ Y+++ ++ AI V+ GG + +PS +V+ S+ N+ +S L Sbjct: 523 QIWDVYYRLNIRDAISFVDQGGHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACLD 582 Query: 616 SERILPALS-KDKEEEI-RKILRNNLQKTRQRLR-SYNRHTLVADPYEEAWNQMLLRRQK 672 + I S +D+E+ + +L L K R+R + S +RH + D E ++ + K Sbjct: 583 LQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMK 642 Query: 673 AR 674 R Sbjct: 643 RR 644 >gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens] Length = 581 Score = 233 bits (595), Expect = 4e-61 Identities = 145/429 (33%), Positives = 243/429 (56%), Gaps = 18/429 (4%) Query: 106 SLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVG-------ETPPFLQS 158 SL +L C++ + +I +PES ++ +G+L+G +IK + + + Sbjct: 65 SLLVLAICIILVHL-LIRYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEMFRP 123 Query: 159 DVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQ 218 ++FFL LLPPII ++GY L F +N+G+I +FAV GT +AF +GG +Y L + Sbjct: 124 NMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYF--LGQADV 181 Query: 219 INNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFE 278 I+ + + D+ FGS+ISAVDPVA +A+F +H++ +L++LVFGES+LNDAV++VL + E Sbjct: 182 ISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAE 241 Query: 279 EFA--NYEHVGIVDIFLGFLSFFV-VALGGVLVGVVYGVIAAFTSRFTSHIRV--IEPLF 333 N V FL L +F+ + G +G + G+I+A + + +E Sbjct: 242 GLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGM 301 Query: 334 VFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSVSETL 393 + +++Y+ Y AE LSGIMA++ SG+VM Y N+S + ++ L+ + + ET Sbjct: 302 MIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETC 361 Query: 394 IFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFIIA 453 +F FLG+S + H + +FVI ++ L R + + L++ +N FR K+TPK FI+ Sbjct: 362 VFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMW 421 Query: 454 YGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAV---KK 510 + GLRGAI ++L LD + L T I ++ FT+ + G + PL+ L+ + K Sbjct: 422 FSGLRGAIPYALSLHLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAKA 481 Query: 511 KQETKRSIN 519 + K+ +N Sbjct: 482 HRRNKKDVN 490 >gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger), member 9 [Homo sapiens] Length = 645 Score = 197 bits (502), Expect = 2e-50 Identities = 125/377 (33%), Positives = 206/377 (54%), Gaps = 12/377 (3%) Query: 159 DVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAV--CLVGG 216 ++FF LLPPII AGY L R F +NLG+IL +A +GT + +G +MY ++ Sbjct: 132 EIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMIHA 191 Query: 217 EQINN--IGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLY 274 Q+ N D L FGS++SA DPV VLA+F E+H++ L+ L+FGES+LNDAV +VL Sbjct: 192 GQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLT 251 Query: 275 HLFEEFANYEHVGIVDIFLGFLS---FFVVALGGVLVGVVYGVIAAFTSRFTS--HIRVI 329 + ++ E+ D F S F + G +G Y +I A ++FT ++ Sbjct: 252 YSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPML 311 Query: 330 EPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSV 389 E FL S+ A+LSAE L+GI+A++ GV Y N+S S K + + + Sbjct: 312 ETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFL 371 Query: 390 SETLIFIFLGVSTVAGSHH-WNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKD 448 +E +IF ++G++ +H +N F++ L +AR + L++ +N R K+ Sbjct: 372 AENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNF 431 Query: 449 QFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAV 508 Q ++ + GLRGAIAF+L + + + P +F T ++ ++FFTV+V G P++ L + Sbjct: 432 QHMMMFSGLRGAIAFALA-IRNTESQPKQMMFTTTLL-LVFFTVWVFGGGTTPMLTWLQI 489 Query: 509 KKKQETKRSINEEIHTQ 525 + + ++ E+ +Q Sbjct: 490 RVGVDLDENLKEDPSSQ 506 >gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger), member 6 isoform a [Homo sapiens] Length = 701 Score = 191 bits (485), Expect = 2e-48 Identities = 132/441 (29%), Positives = 223/441 (50%), Gaps = 51/441 (11%) Query: 109 ILLACLMKIGFHVIPTISSIV--------PESCLLIVVGLLVGGLIKGVGETPPF----- 155 +L+ +++ G HV ++++ P + L+ V G ++KG + Sbjct: 110 LLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQD 169 Query: 156 --------LQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGL 207 +VFF LLPPII AGY L R F NLG+IL +A +GT + F +G + Sbjct: 170 NEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSI 229 Query: 208 MYA---VCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESL 264 MY + V G+ + D LLFG+I+SA DPV VLA+F E+ ++ L+ L+FGES+ Sbjct: 230 MYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESV 289 Query: 265 LNDAVTVVL-------------YHLFEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVV 311 LNDAV +VL H F+ A ++ +G IFLG S G +G Sbjct: 290 LNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIG---IFLGIFS------GSFAMGAA 340 Query: 312 YGVIAAFTSRFTS--HIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEA 369 GV+ A ++FT +++E FL S+ +L AE + +G++A++ G+ Y Sbjct: 341 TGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYN 400 Query: 370 NISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHH-WNWTFVISTLLFCLIARVLG 428 N+S +S K ++ + ++E IF ++G++ +H +N TFV+ + + R Sbjct: 401 NLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAAN 460 Query: 429 VLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVI 488 + L+ +N R K+ Q ++ + GLRGA+AF+L + D + +F T ++ ++ Sbjct: 461 IYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALA-IRDTATYARQMMFSTTLL-IV 518 Query: 489 FFTVFVQGMTIRPLVDLLAVK 509 FFTV+V G ++ L ++ Sbjct: 519 FFTVWVFGGGTTAMLSCLHIR 539 >gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger), member 6 isoform b [Homo sapiens] Length = 669 Score = 190 bits (483), Expect = 4e-48 Identities = 122/370 (32%), Positives = 199/370 (53%), Gaps = 30/370 (8%) Query: 159 DVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYA---VCLVG 215 +VFF LLPPII AGY L R F NLG+IL +A +GT + F +G +MY + V Sbjct: 149 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 208 Query: 216 GEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVL-- 273 G+ + D LLFG+I+SA DPV VLA+F E+ ++ L+ L+FGES+LNDAV +VL Sbjct: 209 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 268 Query: 274 -----------YHLFEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRF 322 H F+ A ++ +G IFLG S G +G GV+ A ++F Sbjct: 269 SIVAYQPAGDNSHTFDVTAMFKSIG---IFLGIFS------GSFAMGAATGVVTALVTKF 319 Query: 323 TS--HIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIK 380 T +++E FL S+ +L AE + +G++A++ G+ Y N+S +S K Sbjct: 320 TKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTK 379 Query: 381 YFLKMWSSVSETLIFIFLGVSTVAGSHH-WNWTFVISTLLFCLIARVLGVLGLTWFINKF 439 ++ + ++E IF ++G++ +H +N TFV+ + + R + L+ +N Sbjct: 380 QLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLG 439 Query: 440 RIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTI 499 R K+ Q ++ + GLRGA+AF+L + D + +F T ++ ++FFTV+V G Sbjct: 440 RRSKIGSNFQHMMMFAGLRGAMAFALA-IRDTATYARQMMFSTTLL-IVFFTVWVFGGGT 497 Query: 500 RPLVDLLAVK 509 ++ L ++ Sbjct: 498 TAMLSCLHIR 507 >gi|14211919 solute carrier family 9, member 7 [Homo sapiens] Length = 725 Score = 186 bits (472), Expect = 8e-47 Identities = 129/387 (33%), Positives = 201/387 (51%), Gaps = 30/387 (7%) Query: 159 DVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCL---VG 215 +VFF LLPPII AGY L R F NLG+IL +A +GT + F +G LMY V + Sbjct: 181 EVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIM 240 Query: 216 GEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVL-- 273 G+ + D L FG+IISA DPV VLA+F E+H + L+ L+FGES+LNDAV +VL Sbjct: 241 GQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSS 300 Query: 274 -----------YHLFEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRF 322 H F+ A ++ VG IFLG S G +G V GV A T Sbjct: 301 SIVAYQPAGLNTHAFDAAAFFKSVG---IFLGIFS------GSFTMGAVTGVNANVTKFT 351 Query: 323 TSH-IRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKY 381 H ++E FL S+ +L AE +G++A++ G+ Y N+S +S + K Sbjct: 352 KLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQ 411 Query: 382 FLKMWSSVSETLIFIFLGVSTVAGSHH-WNWTFVISTLLFCLIARVLGVLGLTWFINKFR 440 ++ ++E IF ++G++ H ++ F+I + + R + L++F+N R Sbjct: 412 LFEVLHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGR 471 Query: 441 IVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIR 500 K+ Q ++ + GLRGA+AF+L + D + +F T ++ ++FFTV++ G Sbjct: 472 RHKIGWNFQHMMMFSGLRGAMAFALA-IRDTASYARQMMFTTTLL-IVFFTVWIIGGGTT 529 Query: 501 PLVDLLAVK-KKQETKRSINEEIHTQF 526 P++ L ++ +E E H Q+ Sbjct: 530 PMLSWLNIRVGVEEPSEEDQNEHHWQY 556 >gi|224465231 solute carrier family 9, member 11 [Homo sapiens] Length = 1124 Score = 56.2 bits (134), Expect = 1e-07 Identities = 72/294 (24%), Positives = 127/294 (43%), Gaps = 39/294 (13%) Query: 154 PFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVC- 212 P L++ F L+ YF PL F L + + + W G + ++ Sbjct: 83 PLLRTSSFSLY---------SYFSPLIIFMVALD-VEFYTLKKMFWQVLLTGLISFSTAS 132 Query: 213 -LVGGEQI----NNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLND 267 ++G I ++ L LLF + +DP+ + + I I+++ L+ GESL+ Sbjct: 133 IIIGYVVIKFNKDSWDLQSCLLFSITLGIIDPLRSVNSLKTIGISKIYIDLIRGESLIIC 192 Query: 268 AVTVVLYHLFEEFANYEHVGIV-DIFLGF-LSFFVVALGGVLVG-----VVYGVIAAFTS 320 ++ + + F N H I D+ +G LS+ + LG ++ G ++ ++A S Sbjct: 193 SIASIFFGNFR--GNRIHFSIFRDLHVGIELSYDI--LGSIIFGYWCAKIIQCILADVFS 248 Query: 321 RFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIK 380 ++I + F YM + E +SG +AL A G+ + K I Sbjct: 249 NMLTNI-----ILCFSMVYMTFYIVEFLGMSGTLALAAVGLNLD---SLTFKPKIELVIT 300 Query: 381 YFLKMWSSVSETLIFIFLGVSTVAG--SHHWNWTFVISTLLFCLI--ARVLGVL 430 FL+++SSV E LI+ F G+ G SH+ T +LF + R+L +L Sbjct: 301 KFLRIFSSVYEHLIYAFFGIVIGCGELSHYEFHTIPFIFILFTTVNLVRLLTIL 354 >gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens] Length = 1177 Score = 54.7 bits (130), Expect = 3e-07 Identities = 54/258 (20%), Positives = 109/258 (42%), Gaps = 30/258 (11%) Query: 155 FLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLV 214 ++ D+FF P + + + + IL+ ++ G L N Y + L Sbjct: 73 WMSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVN--------YILVLW 124 Query: 215 GGEQINNIGLLDN--LLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVV 272 +N + L LLF +I+ + DP+ A ++ ++ L L+ GESL+ ++++ Sbjct: 125 HLASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLI 184 Query: 273 LYHLFEEF-----ANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAF--TSRFTSH 325 + +F + H +I G S+ + + L G++ + F ++ F Sbjct: 185 TFTSIMDFDQRLQSKRNHTLAEEIVGGICSYIIASF---LFGILSSKLIQFWMSTVFGDD 241 Query: 326 IRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKM 385 + I +F L Y+ + EL +SGI L G+++ + S K+ L+ Sbjct: 242 VNHISLIFSIL--YLIFYICELVGMSGIFTLAIVGLLLN-----STSFKAAIEETLLLEF 294 Query: 386 W---SSVSETLIFIFLGV 400 W S ++ ++F F G+ Sbjct: 295 WTFLSRIAFLMVFTFFGL 312 >gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sapiens] Length = 913 Score = 38.5 bits (88), Expect = 0.025 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 8/101 (7%) Query: 720 DPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDED-----DDGGIMMRSKETSSPGT 774 +PA+P PE VDL+ L+G + S P + + GG + G Sbjct: 487 EPAAPPPPEDVDLLG--LEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGV 544 Query: 775 DDVFTPA-PSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKG 814 +DVF P+ P+ + S+ R + P GEG F P G Sbjct: 545 EDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFG 585 >gi|4505101 microtubule-associated protein 7 [Homo sapiens] Length = 749 Score = 34.7 bits (78), Expect = 0.37 Identities = 42/189 (22%), Positives = 75/189 (39%), Gaps = 25/189 (13%) Query: 641 KTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINN--YLTVPAHKLDSPTMSR 698 K S +R L P E + + ++ + + E++ N +LT + SP+ + Sbjct: 261 KAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNPK 320 Query: 699 AR--------IGSDPLAYEPKEDLPVITIDPAS---------PQSPESVDLVNEELK--G 739 AR + S L + P P ++ P S P SP ++ V E+K Sbjct: 321 ARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGSVKAAPAQVRPPSPGNIRPVKREVKVEP 380 Query: 740 KVLGLSRDPAKVAEEDEDDDGGIMMRSKETS----SPGTDDVFTPAPSDSPSSQRIQRCL 795 + ++P KVA E +++ +E + +P +V AP+ +P+ Sbjct: 381 EKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAPA 440 Query: 796 SDPGPHPEP 804 S P P P P Sbjct: 441 SAPAPAPVP 449 >gi|75750492 phosphatidylinositol glycan, class W [Homo sapiens] Length = 504 Score = 34.7 bits (78), Expect = 0.37 Identities = 50/223 (22%), Positives = 90/223 (40%), Gaps = 39/223 (17%) Query: 233 IISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIF 292 ++ V VA L ++ + ELL +++FG L LY ++ Y + + I Sbjct: 62 VVLIVPMVATLTIWASFILLELLGVIIFGAGL--------LYQIYRRRTCYARLPFLKIL 113 Query: 293 LGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFV--FLYSYMAYLSAELFHL 350 FL+ + + + + +AFT+ + + V PLF F + + A F + Sbjct: 114 EKFLNISLESEYNPAISCFRVITSAFTA--IAILAVDFPLFPRRFAKTELYGTGAMDFGV 171 Query: 351 SGIM---ALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVA--- 404 G + A++ V R Y+E + H YF +S+ +FLG+ +A Sbjct: 172 GGFVFGSAMVCLEVRRRKYMEGSKLH-------YFT---NSLYSVWPLVFLGIGRLAIIK 221 Query: 405 ----GSH------HWNWTF-VISTLLFCLIARVLGVLGLTWFI 436 H HWN+ F +I L + ++ L +W I Sbjct: 222 SIGYQEHLTEYGVHWNFFFTIIVVKLITPLLLIIFPLNKSWII 264 >gi|223717983 solute carrier family 37 (glycerol-3-phosphate transporter), member 2 isoform 2 [Homo sapiens] Length = 501 Score = 34.3 bits (77), Expect = 0.48 Identities = 41/194 (21%), Positives = 89/194 (45%), Gaps = 30/194 (15%) Query: 257 ILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFF----------VVALGGV 306 I FG + V L LF + +Y + + +++ ++ F + +GG+ Sbjct: 286 ISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIANVAHFSAKEAGDLSTLFDVGGI 345 Query: 307 LVGVVYGVIAAFTS-RFTS--HIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVM 363 + G+V G+++ +T+ R T+ + ++ +FLY+ Y+ + S +M +I G+V Sbjct: 346 IGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYN---YIGQDGIASSIVMLIICGGLVN 402 Query: 364 RPY------VEANI-SHKS-------HTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHW 409 PY V A++ +HKS +T+ + S+ L + G+ + G ++ Sbjct: 403 GPYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLISPTGWNNV 462 Query: 410 NWTFVISTLLFCLI 423 + + + +L CL+ Sbjct: 463 FYMLISADVLACLL 476 >gi|38093649 solute carrier family 37 (glycerol-3-phosphate transporter), member 2 isoform 1 [Homo sapiens] Length = 505 Score = 34.3 bits (77), Expect = 0.48 Identities = 41/194 (21%), Positives = 89/194 (45%), Gaps = 30/194 (15%) Query: 257 ILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFF----------VVALGGV 306 I FG + V L LF + +Y + + +++ ++ F + +GG+ Sbjct: 286 ISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIANVAHFSAKEAGDLSTLFDVGGI 345 Query: 307 LVGVVYGVIAAFTS-RFTS--HIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVM 363 + G+V G+++ +T+ R T+ + ++ +FLY+ Y+ + S +M +I G+V Sbjct: 346 IGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYN---YIGQDGIASSIVMLIICGGLVN 402 Query: 364 RPY------VEANI-SHKS-------HTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHW 409 PY V A++ +HKS +T+ + S+ L + G+ + G ++ Sbjct: 403 GPYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLISPTGWNNV 462 Query: 410 NWTFVISTLLFCLI 423 + + + +L CL+ Sbjct: 463 FYMLISADVLACLL 476 >gi|71274109 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon [Homo sapiens] Length = 500 Score = 33.9 bits (76), Expect = 0.62 Identities = 36/124 (29%), Positives = 47/124 (37%), Gaps = 15/124 (12%) Query: 695 TMSRARIGSD----PLAYEPKEDLPVITIDP----ASPQSPESVDLVNEELKGKVLGLS- 745 T+S R G P P+ P+ DP A+ +S E + G+S Sbjct: 83 TLSSLRAGPSEPHSPGRRPPRAGRPLCQADPQPGKAARRSLEPDPAQTGPRPARAAGMSE 142 Query: 746 -RDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEP 804 R AEE + D G +RS + T AP+ PS Q C PGP EP Sbjct: 143 ARKGPDEAEESQYDSGIESLRSLRSLPESTS-----APASGPSDGSPQPCTHPPGPVKEP 197 Query: 805 GEGE 808 E E Sbjct: 198 QEKE 201 >gi|117606370 UMP-CMP kinase 2 [Homo sapiens] Length = 449 Score = 33.5 bits (75), Expect = 0.81 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Query: 557 YVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPS 616 Y+ IA E +K P ++ Y AI SGG+ +P A V P+ L Sbjct: 312 YIVASEIAKESAKSPVIVDRYWHSTATYAIATEVSGGLQHLPPAHHPVYQ---WPEDLLK 368 Query: 617 ERILPALSKDKEEEIRKILRNNLQKTRQ 644 ++ L+ EE ++++ ++KTR+ Sbjct: 369 PDLILLLTVSPEERLQRLQGRGMEKTRE 396 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 33.5 bits (75), Expect = 0.81 Identities = 41/165 (24%), Positives = 65/165 (39%), Gaps = 22/165 (13%) Query: 654 LVADPYEEAWNQMLLR-RQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKE 712 L+ + +A N+ + + + +QL Q T+ +S M +R +P E Sbjct: 410 LLTERLRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMGASRRPPEP------E 463 Query: 713 DLPVITIDPASPQSPESVDLVNEELKGK-VLGLSRDPAKVAEEDEDDDGGIMMRSKETSS 771 P PA+P P +++L EEL+ K ++ + R P D I + ++ Sbjct: 464 KAP-----PAAPTRPSALELKVEELEEKGLIRILRGPG--------DAVSIEILPVAVAT 510 Query: 772 PGTDDVFTP-APSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ 815 P D TP P+ SPS PG P P P P Q Sbjct: 511 PSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQ 555 >gi|150456444 hypothetical protein LOC57578 [Homo sapiens] Length = 2458 Score = 33.1 bits (74), Expect = 1.1 Identities = 22/102 (21%), Positives = 44/102 (43%), Gaps = 4/102 (3%) Query: 686 VPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLS 745 +P +L+ ++ S P+ PKEDL +I + S PE +++ ++ Sbjct: 1401 IPEVRLNCMETFEVKVDS-PVKPAPKEDLDLIDLSSDSTSGPEKHSILSTSDSDSLVFEP 1459 Query: 746 RDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPS 787 P ++ E DE+++ M + G + +P+ PS Sbjct: 1460 LPPLRIVESDEEEE---TMNQGDDGPSGKNAASSPSVPSHPS 1498 >gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens] Length = 473 Score = 32.0 bits (71), Expect = 2.4 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 21/100 (21%) Query: 718 TIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDV 777 T PAS +SP + EL G+VL + + + EED+DD +D Sbjct: 186 TESPASTESPVGGE--GSEL-GEVLQIQVEEEEEEEEDDDD----------------EDQ 226 Query: 778 FTPAPSDSPSSQRIQRCLSDP-GPHPEPGEGEP-FFPKGQ 815 + S +P QR+ P GPHP P P P+G+ Sbjct: 227 GSATLSQTPQPQRVSGVFPRPHGPHPLPMTATPRKLPEGE 266 >gi|194097341 period 1 [Homo sapiens] Length = 1290 Score = 31.6 bits (70), Expect = 3.1 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 9/52 (17%) Query: 762 IMMRSKETSSPGTDDVFT-PAPSDSPS--------SQRIQRCLSDPGPHPEP 804 ++ R K ++P +DVFT PAPS +PS S++I R L P P P Sbjct: 455 VLGRHKVRTAPLNEDVFTPPAPSPAPSLDTDIQELSEQIHRLLLQPVHSPSP 506 >gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo sapiens] Length = 1134 Score = 31.6 bits (70), Expect = 3.1 Identities = 51/247 (20%), Positives = 92/247 (37%), Gaps = 38/247 (15%) Query: 583 KQAIELVESGGMGKI----PSAVSTVSMQNIH-----PKSLPSERILPALS---KDKEEE 630 +Q E + S GK P S+Q H P+ L ++LP LS +++ + Sbjct: 663 QQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDA 722 Query: 631 IRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHK 690 + LR L + L+ + T P ++L +R +E ++VP++ Sbjct: 723 DLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMET-----ISVPSYP 777 Query: 691 LDSPTM-----SRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLS 745 S ++ S I + L EP++++ + + SP+ + N ++ GL Sbjct: 778 SKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLD 837 Query: 746 RDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPG 805 +P E D+ + + E +P V + P P P P Sbjct: 838 YEP-----EGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYP-----------PYPPPPYP 881 Query: 806 EGEPFFP 812 GEP P Sbjct: 882 SGEPEGP 888 >gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo sapiens] Length = 1005 Score = 31.6 bits (70), Expect = 3.1 Identities = 51/247 (20%), Positives = 92/247 (37%), Gaps = 38/247 (15%) Query: 583 KQAIELVESGGMGKI----PSAVSTVSMQNIH-----PKSLPSERILPALS---KDKEEE 630 +Q E + S GK P S+Q H P+ L ++LP LS +++ + Sbjct: 534 QQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDA 593 Query: 631 IRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHK 690 + LR L + L+ + T P ++L +R +E ++VP++ Sbjct: 594 DLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMET-----ISVPSYP 648 Query: 691 LDSPTM-----SRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLS 745 S ++ S I + L EP++++ + + SP+ + N ++ GL Sbjct: 649 SKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLD 708 Query: 746 RDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPG 805 +P E D+ + + E +P V + P P P P Sbjct: 709 YEP-----EGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYP-----------PYPPPPYP 752 Query: 806 EGEPFFP 812 GEP P Sbjct: 753 SGEPEGP 759 >gi|117938768 GNAS complex locus alex [Homo sapiens] Length = 626 Score = 31.6 bits (70), Expect = 3.1 Identities = 50/226 (22%), Positives = 80/226 (35%), Gaps = 26/226 (11%) Query: 599 SAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYN----RHTL 654 +A S S + SLP LP+ S+ K L + L +R + R L Sbjct: 190 AASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAAPGWRSPDPRSRL 249 Query: 655 VADPY-----EEAWN--QMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLA 707 A P W Q L + +R E +I + + D + + +PL Sbjct: 250 AAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRE-----SEQRDPQLRRKQQRWKEPLM 304 Query: 708 YEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSK 767 +E P+ DP P P+ + L + L+ + + P K+ + S+ Sbjct: 305 PRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQPILTPGHSQ 364 Query: 768 ETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPK 813 +PG P P +P R L+ P P P G P P+ Sbjct: 365 PIPTPG--QPLPPQPIPTPG-----RPLT---PQPIPTPGRPLTPQ 400 >gi|10835242 protein kinase, cGMP-dependent, type I isoform 2 [Homo sapiens] Length = 686 Score = 31.2 bits (69), Expect = 4.0 Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 31/115 (26%) Query: 623 LSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINN 682 L D+++E+ + L+N L K R +R + ++Q A L+ + Sbjct: 30 LELDQKDELIQKLQNELDKYRSVIRPATQQA---------------QKQSASTLQGE--- 71 Query: 683 YLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEEL 737 P R I ++P A++ +DL +T+ P P+SP+S DL+ E + Sbjct: 72 -----------PRTKRQAISAEPTAFDI-QDLSHVTL-PFYPKSPQSKDLIKEAI 113 >gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens] Length = 533 Score = 31.2 bits (69), Expect = 4.0 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 6/95 (6%) Query: 711 KEDLPVITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDED--DDGGIMMRSKE 768 +E + T P P+ PE + +EE G D + +D+D DDG ++E Sbjct: 76 EERRSIFTRKPQVPRFPEETES-HEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEE 134 Query: 769 TSSPGTDDV-FTPAPSDSPSSQRIQRCLSDPGPHP 802 +P DD + P PS+ + +Q + P P Sbjct: 135 EEAPVEDDADYEPPPSN--DEEALQNSILPAKPFP 167 >gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] Length = 1090 Score = 31.2 bits (69), Expect = 4.0 Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 5/54 (9%) Query: 761 GIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKG 814 G+ R + T P T TP P SSQ+IQ+ +S P P G P FP G Sbjct: 493 GLPSRQRPTLLPATGS--TPQPG---SSQQIQQRISVPPSPTYPPAGPPAFPAG 541 >gi|197927160 solute carrier family 4, sodium bicarbonate cotransporter, member 4 isoform 3 [Homo sapiens] Length = 1094 Score = 30.8 bits (68), Expect = 5.3 Identities = 45/202 (22%), Positives = 79/202 (39%), Gaps = 46/202 (22%) Query: 139 GLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTL 198 G GGLIK + PF SD + + + + ++F + T+ Sbjct: 440 GRFCGGLIKDIKRKAPFFASDFYDALNIQAL------------------SAILFIYLATV 481 Query: 199 WNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLH-- 256 NA GGL+ G N G+L++ L G+ +S A+ +F + L Sbjct: 482 TNAITFGGLL------GDATDNMQGVLESFL-GTAVSG----AIFCLFAGQPLTILSSTG 530 Query: 257 -ILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVI 315 +LVF L N F + N++++ +++G S F+ +LV + Sbjct: 531 PVLVFERLLFN----------FSKDNNFDYLEF-RLWIGLWSAFLCL---ILVATDASFL 576 Query: 316 AAFTSRFTSHIRVIEPLFVFLY 337 + +RFT F+F+Y Sbjct: 577 VQYFTRFTEEGFSSLISFIFIY 598 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.141 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,961,873 Number of Sequences: 37866 Number of extensions: 1559330 Number of successful extensions: 5849 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 5775 Number of HSP's gapped (non-prelim): 81 length of query: 815 length of database: 18,247,518 effective HSP length: 111 effective length of query: 704 effective length of database: 14,044,392 effective search space: 9887251968 effective search space used: 9887251968 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.