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Search of human proteins with 27734761
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27734761 non-SMC element 2, MMS21 homolog [Homo sapiens]
(247 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27734761 non-SMC element 2, MMS21 homolog [Homo sapiens] 490 e-139
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 39 0.004
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 39 0.004
gi|21687119 spermatogenesis associated 18 homolog [Homo sapiens] 36 0.035
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 36 0.035
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 35 0.046
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 35 0.060
gi|87241872 ring finger protein 151 [Homo sapiens] 33 0.18
gi|71061468 centromere protein E [Homo sapiens] 33 0.30
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 33 0.30
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 33 0.30
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 33 0.30
gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens] 33 0.30
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 32 0.51
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 32 0.51
gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [H... 32 0.51
gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [H... 32 0.51
gi|12232469 required for meiotic nuclear division 5 homolog A [H... 32 0.51
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 32 0.67
gi|34304336 ring finger protein 8 isoform 2 [Homo sapiens] 32 0.67
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 32 0.67
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 32 0.67
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 32 0.67
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 32 0.67
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 32 0.67
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 31 0.87
gi|189571685 WD repeat, sterile alpha motif and U-box domain con... 31 0.87
gi|189571683 WD repeat, sterile alpha motif and U-box domain con... 31 0.87
gi|189571681 WD repeat, sterile alpha motif and U-box domain con... 31 0.87
gi|39725957 DAZ interacting protein 1 isoform 2 [Homo sapiens] 31 0.87
>gi|27734761 non-SMC element 2, MMS21 homolog [Homo sapiens]
Length = 247
Score = 490 bits (1262), Expect = e-139
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MPGRSSSNSGSTGFISFSGVESALSSLKNFQACINSGMDTASSVALDLVESQTEVSSEYS 60
MPGRSSSNSGSTGFISFSGVESALSSLKNFQACINSGMDTASSVALDLVESQTEVSSEYS
Sbjct: 1 MPGRSSSNSGSTGFISFSGVESALSSLKNFQACINSGMDTASSVALDLVESQTEVSSEYS 60
Query: 61 MDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADF 120
MDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADF
Sbjct: 61 MDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADF 120
Query: 121 QNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPV 180
QNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPV
Sbjct: 121 QNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPV 180
Query: 181 KNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSHTDIRKSDLIQDEALRRAIENHNK 240
KNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSHTDIRKSDLIQDEALRRAIENHNK
Sbjct: 181 KNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSHTDIRKSDLIQDEALRRAIENHNK 240
Query: 241 KRHRHSE 247
KRHRHSE
Sbjct: 241 KRHRHSE 247
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 38.9 bits (89), Expect = 0.004
Identities = 46/203 (22%), Positives = 96/203 (47%), Gaps = 25/203 (12%)
Query: 48 LVESQTEVSSEYSMDKAMVEFATLDRQLNHY------VKAVQSTINHVKEERP---EKIP 98
L ES E SS+ S K E + ++L HY + +++ ++H+++E +KI
Sbjct: 592 LHESIKETSSKLS--KIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649
Query: 99 DLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDEDI 158
+LK+ EK AL+ +NS+ + +N + K+ L K E + ++ +E++
Sbjct: 650 NLKITCEK-IEALEQENSELERENRK----LKKTLDSFKNLTFQLESLEKENSQLDEENL 704
Query: 159 IVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSHT 218
+ ++ + C K + ++NK E++ + + +E + KK ++
Sbjct: 705 ELRRNVESLKCASMKMAQLQ-LENKELES--EKEQLKKGLELLKASFKKTERLEVSYQGL 761
Query: 219 DIRKSDLIQDEALRRAIENHNKK 241
DI +++ L++ +EN NKK
Sbjct: 762 DI------ENQRLQKTLENSNKK 778
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 38.9 bits (89), Expect = 0.004
Identities = 46/203 (22%), Positives = 96/203 (47%), Gaps = 25/203 (12%)
Query: 48 LVESQTEVSSEYSMDKAMVEFATLDRQLNHY------VKAVQSTINHVKEERP---EKIP 98
L ES E SS+ S K E + ++L HY + +++ ++H+++E +KI
Sbjct: 592 LHESIKETSSKLS--KIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649
Query: 99 DLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDEDI 158
+LK+ EK AL+ +NS+ + +N + K+ L K E + ++ +E++
Sbjct: 650 NLKITCEK-IEALEQENSELERENRK----LKKTLDSFKNLTFQLESLEKENSQLDEENL 704
Query: 159 IVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSHT 218
+ ++ + C K + ++NK E++ + + +E + KK ++
Sbjct: 705 ELRRNVESLKCASMKMAQLQ-LENKELES--EKEQLKKGLELLKASFKKTERLEVSYQGL 761
Query: 219 DIRKSDLIQDEALRRAIENHNKK 241
DI +++ L++ +EN NKK
Sbjct: 762 DI------ENQRLQKTLENSNKK 778
>gi|21687119 spermatogenesis associated 18 homolog [Homo sapiens]
Length = 538
Score = 35.8 bits (81), Expect = 0.035
Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Query: 27 LKNFQACINSGMDTASSVALDLVESQTEVSSEYSMDKAMVEFATLDRQLNHYVKAVQSTI 86
++ + +NS + V DLVE TE + E S +++ + + ++N K ++S
Sbjct: 121 MQQLDSNLNSTRSQCNQVQDDLVE--TEKNLEESKNRSAISLLAAEEEINQLKKQLKSL- 177
Query: 87 NHVKEERPEKIPDLKL----------LVEKKFLALQSKNSDADFQNNEKFVQFKQQLKEL 136
+E+ + D + L E+K S +AD Q+ E +K+QL+ L
Sbjct: 178 -QAQEDARHRNTDQRSSENRRSEPWSLEERKREQWNSLKQNADQQDTEAMSDYKKQLRNL 236
Query: 137 KKQCG-LQADREA 148
K++ L A++ A
Sbjct: 237 KEEIAVLSAEKSA 249
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 35.8 bits (81), Expect = 0.035
Identities = 54/226 (23%), Positives = 99/226 (43%), Gaps = 32/226 (14%)
Query: 24 LSSLKNFQACI----NSGMDTASSVALDLVESQTEVSSEYSMDKAMVEFATLDRQLNHYV 79
L+ L+ AC+ +S M S+ +L +S+ +VS S + L+ Q+ + +
Sbjct: 238 LNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQIIN-L 296
Query: 80 KAVQSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQ 139
+A S + V E K+ + +V +K +LQ ++ E+ ++ K L E KQ
Sbjct: 297 EAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQ--------ESKEECIKLKVDLLEQTKQ 348
Query: 140 CGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIE 199
G +A+R+ + E++ Q KK V K+ EE+ + R +
Sbjct: 349 -GKRAERQRNEALYNAEELSKAFQQ-----------YKKKVAEKLEKVQAEEEILERNLT 396
Query: 200 SRQKRKKKAYCPQIGCSHTDIRKSDL-IQDEALRRAIENHNKKRHR 244
+ +K K+ Q C + KS+L I E LR+ E +N + +
Sbjct: 397 NCEKENKRL---QERCG---LYKSELEILKEKLRQLKEENNNGKEK 436
Score = 32.0 bits (71), Expect = 0.51
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 27 LKNFQACINSGMDTASSVALDLVESQTEVSSE----YSMDKAMVEFATLDRQLNHYVKAV 82
L+ Q + T + +L E + E+ + MD+A+ E +Q V +
Sbjct: 1090 LQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHL 1149
Query: 83 QSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGL 142
TI + E +KI L+ +EK L L+ N + N+K K+QL+E K+ L
Sbjct: 1150 DMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIE-SLNDKLQNAKEQLRE-KEFIML 1207
Query: 143 QADRE 147
Q ++E
Sbjct: 1208 QNEQE 1212
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 35.4 bits (80), Expect = 0.046
Identities = 49/223 (21%), Positives = 97/223 (43%), Gaps = 24/223 (10%)
Query: 26 SLKNFQACINSGMDTASSVALDLVESQTEVSSEYSMDKAMVEFATLDRQLNHYVKAVQST 85
S + QA S +D + + DL + E + K + E + L++QL
Sbjct: 465 STQTVQALQYSTVDGPLTASKDLEIKNLKEEIE-KLRKQVTESSHLEQQLEE-------- 515
Query: 86 INHVKEERPEKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQAD 145
N V++E + +K EK+ LQ + D + + + + K Q KELK
Sbjct: 516 ANAVRQELDDAFRQIKAY-EKQIKTLQQEREDLNKELVQASERLKNQSKELK---DAHCQ 571
Query: 146 READGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIES-RQKR 204
R+ E ++ + +T+ T K+++ + V++K E D +++ +ES RQ+
Sbjct: 572 RKLAMQEFMEINERLTELHTQ------KQKLARHVRDK----EEEVDLVMQKVESLRQEL 621
Query: 205 KKKAYCPQIGCSHTDIRKSDLIQDEALRRAIENHNKKRHRHSE 247
++ + HT+ ++ +D LR E+++K+ E
Sbjct: 622 RRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELE 664
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 35.0 bits (79), Expect = 0.060
Identities = 43/243 (17%), Positives = 100/243 (41%), Gaps = 29/243 (11%)
Query: 5 SSSNSGSTGFISFSGVESALSSLKNFQACINSGMDTASSVALDLVESQTEVSSEYSMDKA 64
+ S +GST S + ++SS + T S ++ L E++ + + K
Sbjct: 748 NDSGTGSTADTSSIDLNLSISSFLS---------KTKDSGSISLQETRRQKKTLKKTRKF 798
Query: 65 MVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADFQNNE 124
+V+ + + V S ++ R +++ +L+ L +++ A Q NS Q +
Sbjct: 799 IVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQ 858
Query: 125 KFVQFKQQLKELKKQCGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKV 184
F +F+Q++ K+Q D++I + Q T ++E ++++
Sbjct: 859 IFRRFEQEMMSKKRQ--------------YDQEIENLEKQQKQTIERLEQEHTNRLRDEA 904
Query: 185 CGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSHTDIRKSDLIQDEALRRAIENHNKKRHR 244
E++ + ++ K +KK ++ + ++RK E ++R E + +H
Sbjct: 905 KRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRK------ELMKRRKEELAQSQHA 958
Query: 245 HSE 247
+
Sbjct: 959 QEQ 961
>gi|87241872 ring finger protein 151 [Homo sapiens]
Length = 245
Score = 33.5 bits (75), Expect = 0.18
Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 10/83 (12%)
Query: 153 GVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQ 212
G D ++ + +NF C + +K+P + C H + + I+R + +RQK CP
Sbjct: 4 GYDLNLFASPPDSNFVCSVCHGVLKRPAR-LPCSHIFCKKCILRWL-ARQKT-----CP- 55
Query: 213 IGCSHTDIRKSDLIQDEALRRAI 235
C ++++ ++ LR+ I
Sbjct: 56 --CCRKEVKRKKVVHMNKLRKTI 76
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 32.7 bits (73), Expect = 0.30
Identities = 27/139 (19%), Positives = 65/139 (46%), Gaps = 12/139 (8%)
Query: 27 LKNFQACINSGMDTASSVALDLVESQTEVSS--------EYSMDKAMVEFATLDRQLN-H 77
LK C+ +T + + ++L E +TE+S+ + + E + Q N
Sbjct: 1479 LKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIK 1538
Query: 78 YVKAVQSTINHVKE-ERPEKIPDLKL-LVEKKFLALQSKNSDADFQNNEKFVQFKQQLKE 135
+ VQ +N +K+ + K D L +E K L L ++ ++ + + ++ K+++K
Sbjct: 1539 QISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQ-EEIQIMIKEKEEMKR 1597
Query: 136 LKKQCGLQADREADGTEGV 154
+++ ++ D+ + T+ +
Sbjct: 1598 VQEALQIERDQLKENTKEI 1616
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 32.7 bits (73), Expect = 0.30
Identities = 31/138 (22%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 20 VESALSSLKNFQACINSGMDTASSVALDLVESQTEVSSEYSMDKAMVEFATLDRQLNHYV 79
+ S S L+N ++ + G + ++ VE ++ S+ ++ ++ L+++ + V
Sbjct: 833 IRSLQSQLQNKESEVLEGAERVRHIS-SKVEELSQALSQKELEITKMDQLLLEKKRD--V 889
Query: 80 KAVQSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQ 139
+ +Q TI EE+ +++ ++ + +K + L N EKF ++K LK+Q
Sbjct: 890 ETLQQTI----EEKDQQVTEISFSMTEKMVQL----------NEEKF-SLGVEIKTLKEQ 934
Query: 140 CGLQADREADGTEGVDED 157
L + E E V+ED
Sbjct: 935 LNLLSRAEEAKKEQVEED 952
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 32.7 bits (73), Expect = 0.30
Identities = 37/158 (23%), Positives = 61/158 (38%), Gaps = 15/158 (9%)
Query: 59 YSMDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVEK--KFLALQSKNS 116
Y + K + E T +++ K + N + E K D+K +K K +N
Sbjct: 328 YELQKRIAEMETQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENK 387
Query: 117 DA-------DFQNNEKFVQFKQQLKELKKQCGLQADREA----DGTEGVDEDIIVTQSQT 165
+ D Q EK + K+L+KQ LQ D+E +II +
Sbjct: 388 EKFTQLDLEDVQVREKLKHATSKAKKLEKQ--LQKDKEKVEEFKSIPAKSNNIINETTTR 445
Query: 166 NFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQK 203
N KE+ +K +K + E + + ESR+K
Sbjct: 446 NNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREK 483
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 32.7 bits (73), Expect = 0.30
Identities = 37/158 (23%), Positives = 61/158 (38%), Gaps = 15/158 (9%)
Query: 59 YSMDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVEK--KFLALQSKNS 116
Y + K + E T +++ K + N + E K D+K +K K +N
Sbjct: 328 YELQKRIAEMETQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENK 387
Query: 117 DA-------DFQNNEKFVQFKQQLKELKKQCGLQADREA----DGTEGVDEDIIVTQSQT 165
+ D Q EK + K+L+KQ LQ D+E +II +
Sbjct: 388 EKFTQLDLEDVQVREKLKHATSKAKKLEKQ--LQKDKEKVEEFKSIPAKSNNIINETTTR 445
Query: 166 NFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQK 203
N KE+ +K +K + E + + ESR+K
Sbjct: 446 NNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREK 483
>gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens]
Length = 245
Score = 32.7 bits (73), Expect = 0.30
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 7/58 (12%)
Query: 156 EDIIVTQSQT--NFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCP 211
ED+ S T +F CP+ +E +K PV+ C H + + + R+ A+CP
Sbjct: 3 EDLSAATSYTEDDFYCPVCQEVLKTPVRTTACQHVFCRKCFLTAM-----RESGAHCP 55
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 32.0 bits (71), Expect = 0.51
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 80 KAVQSTINHVKEERP-------EKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQ 132
+A+Q+ + K ER EK+ L+ + K A+ S D+ E + +++
Sbjct: 1240 EAIQTALKEFKLEREVVEKELLEKVKHLENQIAKS-PAIDSTRGDSSSLVAELQEKLQEE 1298
Query: 133 LKELKKQCGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKK 178
+ +Q Q R+ + + V +I Q QTNF +T+E+M+K
Sbjct: 1299 KAKFLEQLEEQEKRKNEEMQNVRTSLIAEQ-QTNFNTVLTREKMRK 1343
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 32.0 bits (71), Expect = 0.51
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 80 KAVQSTINHVKEERP-------EKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQ 132
+A+Q+ + K ER EK+ L+ + K A+ S D+ E + +++
Sbjct: 1240 EAIQTALKEFKLEREVVEKELLEKVKHLENQIAKS-PAIDSTRGDSSSLVAELQEKLQEE 1298
Query: 133 LKELKKQCGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKK 178
+ +Q Q R+ + + V +I Q QTNF +T+E+M+K
Sbjct: 1299 KAKFLEQLEEQEKRKNEEMQNVRTSLIAEQ-QTNFNTVLTREKMRK 1343
>gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [Homo
sapiens]
Length = 453
Score = 32.0 bits (71), Expect = 0.51
Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 16/116 (13%)
Query: 40 TASSVALDLVESQTEVSSEY-SMDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIP 98
T +A L QT+V + S++ + + ++ +KA+Q T N + +P I
Sbjct: 47 TTCGIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMI- 105
Query: 99 DLKLLVEKKFL--------ALQSKNSDADF------QNNEKFVQFKQQLKELKKQC 140
D L +K L ++ + +S + NN+K V K+++ +L+ QC
Sbjct: 106 DAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQC 161
>gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [Homo
sapiens]
Length = 437
Score = 32.0 bits (71), Expect = 0.51
Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 16/116 (13%)
Query: 40 TASSVALDLVESQTEVSSEY-SMDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIP 98
T +A L QT+V + S++ + + ++ +KA+Q T N + +P I
Sbjct: 47 TTCGIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMI- 105
Query: 99 DLKLLVEKKFL--------ALQSKNSDADF------QNNEKFVQFKQQLKELKKQC 140
D L +K L ++ + +S + NN+K V K+++ +L+ QC
Sbjct: 106 DAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQC 161
>gi|12232469 required for meiotic nuclear division 5 homolog A [Homo
sapiens]
Length = 391
Score = 32.0 bits (71), Expect = 0.51
Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 167 FTCPITKEEM--KKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCP 211
F CPI +++ P VCGH DA+ +M + K YCP
Sbjct: 334 FACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNG--SKLKCPYCP 378
>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
Length = 2382
Score = 31.6 bits (70), Expect = 0.67
Identities = 54/251 (21%), Positives = 108/251 (43%), Gaps = 40/251 (15%)
Query: 9 SGSTGFISFSGVESALSSLKNFQACINSGMDTASSVALDLVESQTEVSSE-YSMDKAMVE 67
+G TG + + L++LK + S + T +A ++ E + + S + Y+ M+E
Sbjct: 358 TGPTGSVKIGDL--GLATLKR-ASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLE 414
Query: 68 FATLDRQLNHYVKAVQ---STINHVKEERPEK--IPDLKLLVE-------KKFLALQSKN 115
AT + + A Q + VK +K IP++K ++E + +++
Sbjct: 415 MATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLL 474
Query: 116 SDADFQ-------------NNEKF-VQFKQQLKELKKQCGLQADREA-----DGTEGVDE 156
+ A FQ + EK ++ +++++KK G D EA D V E
Sbjct: 475 NHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPE 534
Query: 157 DIIVTQSQTNFTCPITKEEMKKPVKNKV--CGHTYEEDAIVRMIESRQKRKK---KAYCP 211
D+ ++ + C + M K +K++V E+ +VR + ++K+++ K
Sbjct: 535 DVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVE 594
Query: 212 QIGCSHTDIRK 222
Q S T I++
Sbjct: 595 QSSASQTGIKQ 605
>gi|34304336 ring finger protein 8 isoform 2 [Homo sapiens]
Length = 448
Score = 31.6 bits (70), Expect = 0.67
Identities = 17/54 (31%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 96 KIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQ-CGLQADREA 148
+I LK+ +++K A+ + N++K VQ +Q+L++L+ Q C QA ++A
Sbjct: 255 RILRLKIQMQEKHEAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQA 308
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 31.6 bits (70), Expect = 0.67
Identities = 17/54 (31%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 96 KIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQ-CGLQADREA 148
+I LK+ +++K A+ + N++K VQ +Q+L++L+ Q C QA ++A
Sbjct: 255 RILRLKIQMQEKHEAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQA 308
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 31.6 bits (70), Expect = 0.67
Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 35/171 (20%)
Query: 52 QTEVSSEYSMDKAMVEFA---TLDRQLNHYVK------------AVQSTINHVKEERPEK 96
Q E+ Y +K + E A T++ + NHYV A+ +N + +K
Sbjct: 703 QKEIEKVYLDNKLLKEQAHNLTIEMK-NHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQK 761
Query: 97 IPDLKLLVEKKFLALQSKNSDADF--------QNNEK--------FVQFKQQLKELKKQC 140
+ KL +EK L S + D + +EK V+ K+QL ELKK+C
Sbjct: 762 YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC 821
Query: 141 GLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEE 191
G ++ T E+ + + +N P+ E K N T E
Sbjct: 822 GEDQEKIHALT---SENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRE 869
Score = 27.7 bits (60), Expect = 9.6
Identities = 24/97 (24%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 43 SVALDLVESQTEVSSEYSMDKAM-VEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLK 101
S D ++ Q E++ + + KA+ +E + + +K ++ + V++ E +K
Sbjct: 442 SAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVK 501
Query: 102 LLVEKKFLALQSK-NSDADFQNNEKFVQFKQQLKELK 137
+ + FLAL+ S+A N+ + K QLK+LK
Sbjct: 502 QM-QTHFLALKEHLTSEAASGNHRLTEELKDQLKDLK 537
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 31.6 bits (70), Expect = 0.67
Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 35/171 (20%)
Query: 52 QTEVSSEYSMDKAMVEFA---TLDRQLNHYVK------------AVQSTINHVKEERPEK 96
Q E+ Y +K + E A T++ + NHYV A+ +N + +K
Sbjct: 716 QKEIEKVYLDNKLLKEQAHNLTIEMK-NHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQK 774
Query: 97 IPDLKLLVEKKFLALQSKNSDADF--------QNNEK--------FVQFKQQLKELKKQC 140
+ KL +EK L S + D + +EK V+ K+QL ELKK+C
Sbjct: 775 YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC 834
Query: 141 GLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEE 191
G ++ T E+ + + +N P+ E K N T E
Sbjct: 835 GEDQEKIHALT---SENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRE 882
Score = 27.7 bits (60), Expect = 9.6
Identities = 24/97 (24%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 43 SVALDLVESQTEVSSEYSMDKAM-VEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLK 101
S D ++ Q E++ + + KA+ +E + + +K ++ + V++ E +K
Sbjct: 455 SAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVK 514
Query: 102 LLVEKKFLALQSK-NSDADFQNNEKFVQFKQQLKELK 137
+ + FLAL+ S+A N+ + K QLK+LK
Sbjct: 515 QM-QTHFLALKEHLTSEAASGNHRLTEELKDQLKDLK 550
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 31.6 bits (70), Expect = 0.67
Identities = 39/216 (18%), Positives = 90/216 (41%), Gaps = 12/216 (5%)
Query: 37 GMDTASSVALDLVESQTEVSSEYSMDKAMVE-----FATLDRQLNHYVKAVQSTINHVKE 91
G+ +A + L +SQ + +E + K ++ ++ +L + + TI +KE
Sbjct: 445 GLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKE 504
Query: 92 ERPEKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREA--- 148
E K+ + +E K+ ++ + E +Q ++ K Q DRE
Sbjct: 505 EEKLKVDKMAHDLEIKWT--ENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAA 562
Query: 149 -DGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKK 207
D + ED++ S I + + ++ T E + + +E +++ ++
Sbjct: 563 RDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQ 622
Query: 208 AYCPQIGCSHTDIRKSDLIQDEALRRAIENHNKKRH 243
+ + +H ++ + E +RA+ENH +++H
Sbjct: 623 RH-KSLKEAHVLAFQTMEEEKEKEQRALENHLQQKH 657
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 31.6 bits (70), Expect = 0.67
Identities = 39/216 (18%), Positives = 90/216 (41%), Gaps = 12/216 (5%)
Query: 37 GMDTASSVALDLVESQTEVSSEYSMDKAMVE-----FATLDRQLNHYVKAVQSTINHVKE 91
G+ +A + L +SQ + +E + K ++ ++ +L + + TI +KE
Sbjct: 565 GLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKE 624
Query: 92 ERPEKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREA--- 148
E K+ + +E K+ ++ + E +Q ++ K Q DRE
Sbjct: 625 EEKLKVDKMAHDLEIKWT--ENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAA 682
Query: 149 -DGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKK 207
D + ED++ S I + + ++ T E + + +E +++ ++
Sbjct: 683 RDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQ 742
Query: 208 AYCPQIGCSHTDIRKSDLIQDEALRRAIENHNKKRH 243
+ + +H ++ + E +RA+ENH +++H
Sbjct: 743 RH-KSLKEAHVLAFQTMEEEKEKEQRALENHLQQKH 777
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 31.2 bits (69), Expect = 0.87
Identities = 36/167 (21%), Positives = 73/167 (43%), Gaps = 36/167 (21%)
Query: 95 EKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREADGTEGV 154
+KI +L+L V K +++S+N+ EK VQ K ++ + +++ L R+ + V
Sbjct: 316 QKIKELELEVLKHTQSIKSQNN-----LQEKLVQEKSKVADAEEKI-LDLQRKLEHAHKV 369
Query: 155 DEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIG 214
+T TC K+++++ +K + +A V+ +++K+K +
Sbjct: 370 ----CLTD-----TCISEKQQLEEKIKEAT-----QNEAKVKQQYQEEQQKRKLLYQNVD 415
Query: 215 CSHTDIR----------------KSDLIQDEALRRAIENHNKKRHRH 245
H +R +S + Q EAL + +EN +K H
Sbjct: 416 ELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENEKRKYDEH 462
>gi|189571685 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 31.2 bits (69), Expect = 0.87
Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Query: 167 FTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQK 203
F CPIT+E MK PV G++YE++A+ I +++
Sbjct: 408 FICPITRELMKDPVIAS-DGYSYEKEAMENWISKKKR 443
>gi|189571683 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 31.2 bits (69), Expect = 0.87
Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Query: 167 FTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQK 203
F CPIT+E MK PV G++YE++A+ I +++
Sbjct: 408 FICPITRELMKDPVIAS-DGYSYEKEAMENWISKKKR 443
>gi|189571681 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 31.2 bits (69), Expect = 0.87
Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Query: 167 FTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQK 203
F CPIT+E MK PV G++YE++A+ I +++
Sbjct: 408 FICPITRELMKDPVIAS-DGYSYEKEAMENWISKKKR 443
>gi|39725957 DAZ interacting protein 1 isoform 2 [Homo sapiens]
Length = 867
Score = 31.2 bits (69), Expect = 0.87
Identities = 25/104 (24%), Positives = 45/104 (43%), Gaps = 3/104 (2%)
Query: 46 LDLVESQTEVSSEYSMDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVE 105
L L S+ E + S + E+ + ++K KE+ +++ +K +
Sbjct: 250 LQLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKLFDRWKEEEKEKLVDEMEKVKEMFM 309
Query: 106 KKFLALQSKNSDADFQNNE---KFVQFKQQLKELKKQCGLQADR 146
K+F L SKNS ++Q +E +Q K + LK + DR
Sbjct: 310 KEFKELTSKNSALEYQLSEIQKSNMQIKSNIGTLKDAHEFKEDR 353
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,448,071
Number of Sequences: 37866
Number of extensions: 345196
Number of successful extensions: 1632
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 1603
Number of HSP's gapped (non-prelim): 133
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.