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Search of human proteins with 27597085
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 531 e-151
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 500 e-142
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 486 e-138
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 466 e-131
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 457 e-129
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 449 e-126
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 434 e-122
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 426 e-120
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 419 e-117
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 405 e-113
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 328 3e-90
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 317 6e-87
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 315 4e-86
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 303 1e-82
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 300 7e-82
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 298 5e-81
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 254 8e-68
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 84 2e-16
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 84 2e-16
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 82 7e-16
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 80 2e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 79 6e-15
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 79 6e-15
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 79 6e-15
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 79 6e-15
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 77 2e-14
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 77 2e-14
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 77 2e-14
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 77 2e-14
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 77 2e-14
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 531 bits (1367), Expect = e-151
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 500 bits (1288), Expect = e-142
Identities = 267/284 (94%), Positives = 275/284 (96%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTS+
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 486 bits (1251), Expect = e-138
Identities = 262/284 (92%), Positives = 272/284 (95%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ +M
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 466 bits (1199), Expect = e-131
Identities = 244/284 (85%), Positives = 267/284 (94%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLEDEL ++QKKLKGTEDELDKY
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
FAERSV KLEK+IDDLEDELYAQKLKYKAISEELDHALNDMTS+
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 457 bits (1176), Expect = e-129
Identities = 246/284 (86%), Positives = 263/284 (92%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ +M
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 449 bits (1156), Expect = e-126
Identities = 233/284 (82%), Positives = 264/284 (92%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + LEE+L+I+ LK+L A DKYS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
FAERSV KLEK+IDDLEDE+YAQK+KYKAISEELD+ALND+TS+
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 434 bits (1116), Expect = e-122
Identities = 235/284 (82%), Positives = 256/284 (90%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ +M
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 426 bits (1096), Expect = e-120
Identities = 222/284 (78%), Positives = 257/284 (90%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
FAERSV KLEK+IDDLE+ L + K + I + LD L ++ ++
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 419 bits (1076), Expect = e-117
Identities = 220/281 (78%), Positives = 251/281 (89%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+E+EL LQKKLKGTEDELDKY
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE LKDAQEKLEL EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE+SE + LEE+L+ + LK+L AA +KYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
FAER+V KLEK+IDDLE++L K + + + LD LN++
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 281
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 405 bits (1041), Expect = e-113
Identities = 219/284 (77%), Positives = 247/284 (86%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ +M
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 328 bits (841), Expect = 3e-90
Identities = 177/238 (74%), Positives = 201/238 (84%)
Query: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
L ++++K++ +++ D E Q +L+ K AEADVASLNRRIQLVEEELDRA
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
EEVARKLVIIESDLERAEERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYE
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED+LY Q + + ++ EL ALN+
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 45.8 bits (107), Expect = 4e-05
Identities = 30/118 (25%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY- 60
+ + +K+ +++ D E A +RAE +E E+ K + + L SL+ + + + D+Y
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 61 ------SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
S+ LK+A+ + E AE+ T E + L ++ E+ R L AL +
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 39.7 bits (91), Expect = 0.003
Identities = 38/179 (21%), Positives = 80/179 (44%), Gaps = 28/179 (15%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGT----EDE 56
+D ++++ E A A+++E K E R+++ E+++ + +LK ED
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
Query: 57 LDKYSEA----------LKDAQEKLELAEKKATDAEADVASLNRRIQLVE---------- 96
KY E L+ A+E+ EL+E K + E ++ ++ ++ +E
Sbjct: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
Query: 97 ----EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 151
EE+ ++L A + E AE++ + E+ + +E + + E+ +LK A
Sbjct: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 317 bits (813), Expect = 6e-87
Identities = 165/237 (69%), Positives = 200/237 (84%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E + R+++EQ+R+MDQ LK L AAE+KYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+ LY+Q + + +S EL L+D+
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 41.6 bits (96), Expect = 8e-04
Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 7/149 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KM++ ++ + A AE EAD+K E K LV ++ L+ TE+ +
Sbjct: 102 EEKMELQEIQLKEAKHIAE--EADRKYEEVARK-----LVIIEGDLERTEERAELAESRC 154
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
++ E++ L ++ A +++ EEE+ ++L A + E AE++ + E
Sbjct: 155 REMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 214
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
+ + +E R E+ + +LK H
Sbjct: 215 KTIDDLEERLYSQLERNRLLSNELKLTLH 243
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 315 bits (806), Expect = 4e-86
Identities = 165/240 (68%), Positives = 197/240 (82%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E + R+++EQ+R+MDQ LK L AAE+KYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLED+L K ++ LD L D+ M
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 248
Score = 99.0 bits (245), Expect = 4e-21
Identities = 64/222 (28%), Positives = 119/222 (53%), Gaps = 20/222 (9%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
++A+K+K+Q+L+ ++A +RAE+ + + + +Q E E+ SL ++++ E+ELD+
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A +KLE AEK A ++E + + R EE+++ + +L A EEA++
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKE-----------------AKHIAEDADRKYE 163
+E R + +IE ++ EE+ E+ E + +E A+ + KYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 164 EVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLK 205
E ++ I+ L+ AE RAE +E V +LE+ + ++ LK
Sbjct: 187 E---EIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLK 225
Score = 49.7 bits (117), Expect = 3e-06
Identities = 30/114 (26%), Positives = 60/114 (52%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ + +K+ +++ D E +RAE AE+ + +++ + ++ L L + + DKY
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E +K +KL+ AE +A AE VA L + I +E++L +E + L++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 303 bits (776), Expect = 1e-82
Identities = 160/237 (67%), Positives = 195/237 (82%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+ LY+Q + + +S EL L+D+
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 43.5 bits (101), Expect = 2e-04
Identities = 35/149 (23%), Positives = 68/149 (45%), Gaps = 7/149 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KM++ ++ + A AE EAD+K E K LV ++ L+ TE+ +
Sbjct: 102 EEKMELQEIQLKEAKHIAE--EADRKYEEVARK-----LVIIEGDLERTEERAELAESKC 154
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+ +E+L+ EA +++ EEE+ ++L A + E AE++ + E
Sbjct: 155 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 214
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
+ + +E R E+ + +LK H
Sbjct: 215 KTIDDLEERLYSQLERNRLLSNELKLTLH 243
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 300 bits (769), Expect = 7e-82
Identities = 160/240 (66%), Positives = 192/240 (80%)
Query: 45 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 104
++++K++ + + D E + Q ++E + AEA+VASLNRRIQLVEEELDRAQE
Sbjct: 9 AVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQE 68
Query: 105 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
RLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEE
Sbjct: 69 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 128
Query: 165 VARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE 224
VARKLVIIE DLER EERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEE
Sbjct: 129 VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
IK+L+DKLKEAETRAEFAERSV KLEK+IDDLED+L K ++ LD L D+ M
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 248
Score = 55.1 bits (131), Expect = 7e-08
Identities = 33/114 (28%), Positives = 61/114 (53%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ + +K+ +++ D E +RAE AE+ E+ K + + L SL+ + + + DKY
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E +K +KL+ AE +A AE VA L + I +E++L +E + L++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 298 bits (762), Expect = 5e-81
Identities = 156/241 (64%), Positives = 197/241 (81%)
Query: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
+ L ++++K++ + + D+ + + Q +L+ ++ AE DVA+LNRRIQLVEEELD
Sbjct: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
Query: 101 RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR 160
RAQERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADR
Sbjct: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
KYEEVARKLVI+E +LERAEERAE+SE + LEE+L+ + LK+L AA +KYS+KED+
Sbjct: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
YEEEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLE++L K + + + LD LN+
Sbjct: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
Query: 281 M 281
+
Sbjct: 245 L 245
Score = 56.6 bits (135), Expect = 2e-08
Identities = 36/114 (31%), Positives = 63/114 (55%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ + +K+ +L+ + E A +RAE +E E+ K + + L SL+ + ++ DKY
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E +K +KL+ AE +A AE VA L + I +EE+L +A+E Q L++
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
Score = 56.2 bits (134), Expect = 3e-08
Identities = 35/164 (21%), Positives = 86/164 (52%), Gaps = 6/164 (3%)
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
+R ++ ++ +A + E++ + + +L + E A+ + R++ ++E +L+RA+ER
Sbjct: 11 KRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERL 70
Query: 184 ELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAETRAE 240
+ +++LEE + D++ + + E++ + E++ E ++K +EA+ + E
Sbjct: 71 ATA---LQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
R + LE ++ E+ +LK + EEL + N++ S+
Sbjct: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSL 171
Score = 40.0 bits (92), Expect = 0.002
Identities = 38/174 (21%), Positives = 81/174 (46%), Gaps = 29/174 (16%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE---DEL 57
+D ++++ E A A+++E K E+R+ + E+++ + +LK + +E
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
Query: 58 D-KYSEA----------LKDAQEKLELAEKKATDAEADVASLNRRIQLVE---------- 96
D KY E L+ A+E+ E++E K D E ++ ++ ++ +E
Sbjct: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKE 182
Query: 97 ----EELDRAQERLATALQKLEEAEKAADESERGMKVIESR-AQKDEEKMEIQE 145
EE+ ++L A + E AE+ + E+ + +E + AQ EE + + +
Sbjct: 183 DKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQ 236
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 254 bits (648), Expect = 8e-68
Identities = 137/230 (59%), Positives = 177/230 (76%), Gaps = 7/230 (3%)
Query: 62 EALKDAQEKLELAEKKATD----AEADVASLNRRIQLVEEELDRAQERLATA---LQKLE 114
+A+K + L+L ++ A D AEAD R + +EEE Q++L ++K
Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E+EKAADESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E
Sbjct: 62 ESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 121
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKE 234
+LER+EERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKE
Sbjct: 122 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKE 181
Query: 235 AETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
AETRAEFAERSV KLEK+IDDLE+ L + K + I + LD L ++ ++
Sbjct: 182 AETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
Score = 152 bits (385), Expect = 2e-37
Identities = 93/210 (44%), Positives = 133/210 (63%), Gaps = 9/210 (4%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SEALKDAQEK---LELAEKKATDAEADVASLNRRI---QLVEEELDRAQERLATALQKLE 114
SE+ K A E +++ E +A E + ++ + + E+ DR E +A +KL
Sbjct: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVA---RKLV 117
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
E + SE +V ESRA++ EE++ + LK E+ K ++ ++ ++E
Sbjct: 118 ILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 177
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTL 204
L+ AE RAE +E V +LE+ + +++TL
Sbjct: 178 KLKEAETRAEFAERSVAKLEKTIDDLEETL 207
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/121 (34%), Positives = 68/121 (56%), Gaps = 14/121 (11%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLK---GTEDEL- 57
+ + +K+ +L+ + E + +RAE AE R++QLE+EL ++ + LK +E+E
Sbjct: 110 EEVARKLVILEGELERSEERAE-------VAESRARQLEEELRTMDQALKSLMASEEEYS 162
Query: 58 ---DKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
DKY E +K +EKL+ AE +A AE VA L + I +EE L A+E Q L+
Sbjct: 163 TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLD 222
Query: 115 E 115
+
Sbjct: 223 Q 223
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 83.6 bits (205), Expect = 2e-16
Identities = 59/250 (23%), Positives = 126/250 (50%), Gaps = 16/250 (6%)
Query: 24 QAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA 83
+ E + E++ + E+++ ++K++ ED++ + E +++ +EK+ E+K E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEEL-----------DRAQERLATALQKLEEAEKAADESERGMKVIES 132
+ + +IQ EEE+ ++ QE++ +K+ E ++ E E M E
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 133 RAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQ 192
+ ++ EE M+ QE +L+E + ++ + K +E K I+ E+ +E+ E + Q +
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK---IQRQEEKIQEQEEKTWRQEKL 491
Query: 193 LEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLE 250
L+++ +I +Q K E + Q+E E+E K+ +K++E E R E + + E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 251 KSIDDLEDEL 260
+ +LE+ L
Sbjct: 552 VRLQELEERL 561
Score = 82.4 bits (202), Expect = 4e-16
Identities = 57/273 (20%), Positives = 137/273 (50%), Gaps = 25/273 (9%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAE 82
+Q E E++ ++ E+++ + K++ E+++ + E + + +EK+ E K E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEE--------AEKAADE----------SE 124
+ +I+ EE++ R +E++ +K++E EK ++ E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
+ M+ + + ++ EE+M QE +++E + + +D + K EV K+ E ++ EE+ +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 185 LSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKED---RYEEEIKVLSDKLKEAETRAEF 241
E ++++ EE+ ++ LK E+K ++E+ R EE++ +K++E E + +
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLK----QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 242 AERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
E + + E + E+++ Q+++ + + E L
Sbjct: 529 QEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 74.7 bits (182), Expect = 9e-14
Identities = 68/302 (22%), Positives = 137/302 (45%), Gaps = 34/302 (11%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL-------DK 59
K L+L + A R E + ++ D + ++ + L K+ EL ++
Sbjct: 156 KKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEE 215
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQKLE 114
E + QEKL L E + ++ + +V L R+++ L +++L +RL LQ +
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
Query: 115 EAEKAADES-----------ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 163
+A E E M E + Q+ EEKM QE++++E + + K
Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335
Query: 164 EVARKLVIIESDLERAEERAELSEGQVRQLEEQL-----RIMDQTLK------ALMAAED 212
E K+ E + R EE+ E ++R+ EE++ +I +Q K + E+
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 213 KYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
K ++E++ +E++ K++E + + E + + E+ I +LE+ + Q+ K + + E
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 273 EL 274
++
Sbjct: 456 KM 457
Score = 68.9 bits (167), Expect = 5e-12
Identities = 63/276 (22%), Positives = 137/276 (49%), Gaps = 23/276 (8%)
Query: 14 DKENALDRAEQA--EADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDKYSEALKDA-- 67
++E+ + R E+ E ++K E K + E+++ +K++ E+E+ + E +++
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 68 --QEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
QEK+ EKK + + + + EE++ +E + +KL E E+ E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + Q+ EEK++ QE + + + + ++ +E+ K+ E + EE+ +
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ-EEKMWRQEEKMWEQEEKMQE 521
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF---- 241
E ++++ EE++R +Q ++ L E+K ++E R +E L ++L + +AE
Sbjct: 522 QEEKMQRQEEKMR--EQEVR-LWQQEEKMQEQEVRLQE----LEERLGKLGQKAELLGGA 574
Query: 242 -AERSVTKLEKSIDDLEDELYAQKLKYKAISEELDH 276
E +L L+ EL +Q+ +++ ++ DH
Sbjct: 575 GRESGSQRLPTLTPILQVELKSQEA--QSLQQQQDH 608
Score = 50.1 bits (118), Expect = 2e-06
Identities = 47/208 (22%), Positives = 104/208 (50%), Gaps = 23/208 (11%)
Query: 82 EADVASLNR-RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
E D SL R + +EEL +E+ A +KL E E + +K ++ + ++ +
Sbjct: 198 ERDAPSLELYRNTITDEEL---KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLV--IIESDL-----ERAEERAELSEGQVRQL 193
+ Q++Q++ A+ ++ + V+ KL + E++L ++ EE+ E ++++
Sbjct: 255 LPQQQLQVE-----ADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
Query: 194 EEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI 253
EE++ +Q LK E + Q+E +E+E +K++E E + E + + E+ I
Sbjct: 310 EEKM--CEQELKIREQEEKMWRQEEKMHEQE-----EKIREQEDKMWRQEEKIREQEEKI 362
Query: 254 DDLEDELYAQKLKYKAISEELDHALNDM 281
+ E++++ Q+ K + E++ +M
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEM 390
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 83.6 bits (205), Expect = 2e-16
Identities = 59/250 (23%), Positives = 126/250 (50%), Gaps = 16/250 (6%)
Query: 24 QAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA 83
+ E + E++ + E+++ ++K++ ED++ + E +++ +EK+ E+K E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEEL-----------DRAQERLATALQKLEEAEKAADESERGMKVIES 132
+ + +IQ EEE+ ++ QE++ +K+ E ++ E E M E
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 133 RAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQ 192
+ ++ EE M+ QE +L+E + ++ + K +E K I+ E+ +E+ E + Q +
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK---IQRQEEKIQEQEEKTWRQEKL 491
Query: 193 LEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLE 250
L+++ +I +Q K E + Q+E E+E K+ +K++E E R E + + E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 251 KSIDDLEDEL 260
+ +LE+ L
Sbjct: 552 VRLQELEERL 561
Score = 82.4 bits (202), Expect = 4e-16
Identities = 57/273 (20%), Positives = 137/273 (50%), Gaps = 25/273 (9%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAE 82
+Q E E++ ++ E+++ + K++ E+++ + E + + +EK+ E K E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEE--------AEKAADE----------SE 124
+ +I+ EE++ R +E++ +K++E EK ++ E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
+ M+ + + ++ EE+M QE +++E + + +D + K EV K+ E ++ EE+ +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 185 LSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKED---RYEEEIKVLSDKLKEAETRAEF 241
E ++++ EE+ ++ LK E+K ++E+ R EE++ +K++E E + +
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLK----QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 242 AERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
E + + E + E+++ Q+++ + + E L
Sbjct: 529 QEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 74.7 bits (182), Expect = 9e-14
Identities = 68/302 (22%), Positives = 137/302 (45%), Gaps = 34/302 (11%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL-------DK 59
K L+L + A R E + ++ D + ++ + L K+ EL ++
Sbjct: 156 KKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEE 215
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQKLE 114
E + QEKL L E + ++ + +V L R+++ L +++L +RL LQ +
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
Query: 115 EAEKAADES-----------ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 163
+A E E M E + Q+ EEKM QE++++E + + K
Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335
Query: 164 EVARKLVIIESDLERAEERAELSEGQVRQLEEQL-----RIMDQTLK------ALMAAED 212
E K+ E + R EE+ E ++R+ EE++ +I +Q K + E+
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 213 KYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
K ++E++ +E++ K++E + + E + + E+ I +LE+ + Q+ K + + E
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 273 EL 274
++
Sbjct: 456 KM 457
Score = 68.9 bits (167), Expect = 5e-12
Identities = 63/276 (22%), Positives = 137/276 (49%), Gaps = 23/276 (8%)
Query: 14 DKENALDRAEQA--EADKKAAEDRSK--QLEDELVSLQKKLKGTEDELDKYSEALKDA-- 67
++E+ + R E+ E ++K E K + E+++ +K++ E+E+ + E +++
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 68 --QEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
QEK+ EKK + + + + EE++ +E + +KL E E+ E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + Q+ EEK++ QE + + + + ++ +E+ K+ E + EE+ +
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ-EEKMWRQEEKMWEQEEKMQE 521
Query: 186 SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF---- 241
E ++++ EE++R +Q ++ L E+K ++E R +E L ++L + +AE
Sbjct: 522 QEEKMQRQEEKMR--EQEVR-LWQQEEKMQEQEVRLQE----LEERLGKLGQKAELLGGA 574
Query: 242 -AERSVTKLEKSIDDLEDELYAQKLKYKAISEELDH 276
E +L L+ EL +Q+ +++ ++ DH
Sbjct: 575 GRESGSQRLPTLTPILQVELKSQEA--QSLQQQQDH 608
Score = 50.1 bits (118), Expect = 2e-06
Identities = 47/208 (22%), Positives = 104/208 (50%), Gaps = 23/208 (11%)
Query: 82 EADVASLNR-RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
E D SL R + +EEL +E+ A +KL E E + +K ++ + ++ +
Sbjct: 198 ERDALSLELYRNTITDEEL---KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLV--IIESDL-----ERAEERAELSEGQVRQL 193
+ Q++Q++ A+ ++ + V+ KL + E++L ++ EE+ E ++++
Sbjct: 255 LPQQQLQVE-----ADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
Query: 194 EEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI 253
EE++ +Q LK E + Q+E +E+E +K++E E + E + + E+ I
Sbjct: 310 EEKM--CEQELKIREQEEKMWRQEEKMHEQE-----EKIREQEDKMWRQEEKIREQEEKI 362
Query: 254 DDLEDELYAQKLKYKAISEELDHALNDM 281
+ E++++ Q+ K + E++ +M
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEM 390
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 81.6 bits (200), Expect = 7e-16
Identities = 55/252 (21%), Positives = 122/252 (48%), Gaps = 21/252 (8%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + ++ EEE+ +E++ +K+ E EK
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E ++ E Q+ EEKM QE ++ E + ++ + K + R EE
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK--------------MRRQEE 495
Query: 182 RAELSEGQVRQLEEQLR----IMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKE 234
+ E ++R+ EE++R +M + + + E+K ++E++ EE+++ +K++E
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 235 AETRAEFAERSV 246
E R E +
Sbjct: 556 QEVRLRQQEEKM 567
Score = 76.3 bits (186), Expect = 3e-14
Identities = 62/282 (21%), Positives = 134/282 (47%), Gaps = 20/282 (7%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEDELVSLQKKLKG 52
+++ K ++Q+ + + L+RA+ QAEAD L EL S+ KL+
Sbjct: 221 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD---------HLGKELQSVSAKLQA 271
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+E + ++ + +EK+ E+K + E + +I+ EE++ R +E + +K
Sbjct: 272 QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
+ E+ E E ++ +E + ++EK+ QE + +E + I E R+ +E K+
Sbjct: 332 MRRQEEMMWEKEEKIRELEEK-MHEQEKIREQEEKRQEEEKIREQEKRQEQEA--KMWRQ 388
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 232
E + EE+ E +++ EE++ ++ + + +K R EE+I+ K+
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+E E + E + + E+ + + E ++ Q+ K + E++
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM 490
Score = 73.9 bits (180), Expect = 1e-13
Identities = 48/259 (18%), Positives = 131/259 (50%), Gaps = 11/259 (4%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKL----ELAE 75
++ ++ E + E++ ++ E+ + ++K++ E+ + + E +++ +EK+ ++ E
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
++ E + + Q E ++ R +E++ +K+ E E+ E E M E +
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 136 KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEE 195
+ EE+M+ QE +++ + + ++K E K+ E ++ EE+ EG++ + E
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481
Query: 196 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
+++ ++ ++ E+K ++E + E+ +K++E E + E + + E+ + +
Sbjct: 482 KMQEQEEKMR---RQEEKIREQEKKIREQ----EEKIREQEEMMQEQEEKMWEQEEKMCE 534
Query: 256 LEDELYAQKLKYKAISEEL 274
E+++ Q+ K + E++
Sbjct: 535 QEEKMQEQEEKMRRQEEKM 553
Score = 73.2 bits (178), Expect = 2e-13
Identities = 56/261 (21%), Positives = 132/261 (50%), Gaps = 15/261 (5%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLEL 73
++E + R E+ +K E++ ++ E+ + ++K++ E+++ + E +++ +EK +
Sbjct: 313 EQEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIREQEEKRQE 368
Query: 74 AEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK 128
EK K + EA + +I+ EE++ +E + +K+ E E+ E E M+
Sbjct: 369 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEG 188
E + ++ EEK+ QE +++E + + + +E K+ E + E + + E
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Query: 189 QVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVL---SDKLKEAETRAEFAERS 245
++R+ EE++R + K + E+K ++E+ +E+ + + +K+ E E + + E
Sbjct: 489 KMRRQEEKIREQE---KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Query: 246 VTKLEKSIDDLEDELYAQKLK 266
+ + E+ + + E L Q+ K
Sbjct: 546 MRRQEEKMREQEVRLRQQEEK 566
Score = 71.6 bits (174), Expect = 7e-13
Identities = 67/267 (25%), Positives = 130/267 (48%), Gaps = 40/267 (14%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-------- 84
++L+++ LQ+KL+ E E + +K+ + KLE A+ ++ AEAD
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 85 -VASL----------NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
A L NR Q EE++ R +E++ +K++E E+ E E M+ E
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 134 AQKDEEKMEIQE---------IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
+ EEKM QE I+ E K ++ R+ EE ++ I +R E+ A+
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 185 L--SEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAETRA 239
+ E ++R+ EE++R ++ ++ E+K ++E++ EEE++ +K++ E +
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQ---EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441
Query: 240 EFAERSVTKLEKSIDDLEDELYAQKLK 266
E+ + + E+ I + E+ + Q+ K
Sbjct: 442 REQEKKIREQEEKIREQEEMMQEQEEK 468
Score = 71.2 bits (173), Expect = 9e-13
Identities = 42/201 (20%), Positives = 104/201 (51%), Gaps = 3/201 (1%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
K + Q + ++E + R E+ ++ E++ ++ E+ + ++K+ E+++ + E +
Sbjct: 371 KIREQEKRQEQEAKMWRQEEKIREQ---EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
++ +EK+ E+K + E + +I+ EE + +E++ K+ E E E E
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQE 487
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
M+ E + ++ E+K+ QE +++E + + ++ + K E K+ E ++ EE+
Sbjct: 488 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547
Query: 185 LSEGQVRQLEEQLRIMDQTLK 205
E ++R+ E +LR ++ ++
Sbjct: 548 RQEEKMREQEVRLRQQEEKMQ 568
Score = 62.4 bits (150), Expect = 4e-10
Identities = 64/269 (23%), Positives = 128/269 (47%), Gaps = 26/269 (9%)
Query: 19 LDRAEQAEADKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
L++A A A +K DR ++L E +L +L ++ E QEKL+L E +
Sbjct: 165 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 224
Query: 78 ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE-EAEKAADESERGMKVIESRA-- 134
++ + +V L R +L+RA +L Q+L+ EA+ E + ++++
Sbjct: 225 KSEIQLNVKELKR-------KLERA--KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 275
Query: 135 --------QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
Q+ EEKM QE +++E + ++ + K E K+ E + EE+
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 187 EGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVL-SDKLKEAETRAEFAERS 245
E + + EE++R +++ M ++K ++E++ +EE K+ +K +E E + E
Sbjct: 336 EEMMWEKEEKIRELEEK----MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 391
Query: 246 VTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+ + E+ I + E+ + Q+ K E++
Sbjct: 392 IREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Score = 29.3 bits (64), Expect = 4.1
Identities = 40/175 (22%), Positives = 68/175 (38%), Gaps = 16/175 (9%)
Query: 108 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQ-----EIQLKEAKHIAED---AD 159
T KL EA++ + A D +K +I E H ED A
Sbjct: 43 TRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKAS 102
Query: 160 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA-AEDKYSQKE 218
+++E R+ +LE + + Q +L+ L +K L A D S+
Sbjct: 103 HQHQEALRR------ELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 156
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 273
D ++ + L L T+ + A+R + +L K D L ELY + + + E+
Sbjct: 157 DSWKFAGE-LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 210
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 80.5 bits (197), Expect = 2e-15
Identities = 60/282 (21%), Positives = 141/282 (50%), Gaps = 15/282 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE---- 117
E +++ +EK+ E+K E ++ + ++ EEE + QE + +K+ E E
Sbjct: 484 EKIREQEEKIREQEEKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 118 --KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
+ E E ++ E + + EEKM QE +++E + E R+ E++ + I
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE---EKVWRQEEKIREQEEKIREQ 597
Query: 176 LERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKL 232
E+ E+ E+++ Q ++ EQ M + + + E+K ++E++ E++I+ +K+
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+E E + E + + E+ + + E+++ Q+ K + E++
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Score = 76.3 bits (186), Expect = 3e-14
Identities = 49/249 (19%), Positives = 123/249 (49%), Gaps = 17/249 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED------ 55
+ I+++ + ++ +E + E+ +K E+ +Q ++E+ ++K++ E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
++ + E ++ +EK+ E+K D E + ++ EE++ +E++ +K+ E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
E+ E E M E + + EEKM+ QE +++ + + ++K E K+ E
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663
Query: 176 LERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLK 233
++ EE+ E ++ + EE+++ ++ ++ Q+E +E+E+++ +K++
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMR---------RQEEKMWEQEVRLRQQEEKMQ 714
Query: 234 EAETRAEFA 242
E + E A
Sbjct: 715 EHQEHLEAA 723
Score = 71.2 bits (173), Expect = 9e-13
Identities = 57/275 (20%), Positives = 130/275 (47%), Gaps = 24/275 (8%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS----EALKDAQE 69
+K ++ ++ EA E++ ++ E+++ ++K+ E+++ + E + QE
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 70 KLELAEKKATDAEA------DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++ E+K + E + +I+ EE++ R +E++ +K+ E E+
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E ++ E + ++ EEK+ QE +E + + + K E K+ E + R EE+
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 184 ELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
E ++R+ EE++R ++ ++ Q+E +E+E +K+ E E + + E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQ---------EQEEKMWEQE-----EKMCEQEEKMQEQE 689
Query: 244 RSVTKLEKSIDDLEDELYAQKLKYKAISEELDHAL 278
+ + E+ + + E L Q+ K + E L+ A+
Sbjct: 690 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 70.1 bits (170), Expect = 2e-12
Identities = 62/247 (25%), Positives = 125/247 (50%), Gaps = 35/247 (14%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-----VAS 87
++L+++ LQ+KL+ E E + +K+ + KLE A+ ++ AEAD + S
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + ++ EEK
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIM 200
M QE + E E+ R+ EE+ + E + R EE E ++R+LEE+
Sbjct: 398 MRRQEEMMWE----KEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEK---- 446
Query: 201 DQTLKALMAAEDKYSQKEDRYEEEIKVL-SDKLKEAETRAEFAERSVTKLEKSIDDLEDE 259
M ++K ++E++ +EE K+ +K +E E + E + + E+ I + E++
Sbjct: 447 -------MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 260 LYAQKLK 266
++ Q+ K
Sbjct: 500 MWRQEEK 506
Score = 70.1 bits (170), Expect = 2e-12
Identities = 55/284 (19%), Positives = 135/284 (47%), Gaps = 19/284 (6%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D + K++Q + + ++ E + E++ + E+++ ++K++ E+++ +
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+ + E + + EE++ R +E + +K+ E E+
Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 122 ESERGMKVIESRAQ----KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
E E+ + E R + +++EK + QE ++ + + + K E K+ E E
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE---E 505
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV---------L 228
+ E+ ++ E + RQ +E++ ++ ++ E+ + QKE +E+E K+
Sbjct: 506 KIHEQEKIREEEKRQEQEEMWRQEEKIR---EQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562
Query: 229 SDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
+K+ + E + E V + E+ I + E+++ Q+ K + E
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606
Score = 67.4 bits (163), Expect = 1e-11
Identities = 66/276 (23%), Positives = 130/276 (47%), Gaps = 12/276 (4%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED----ELDKYSE 62
K + KL ++ L +E++E E + K +L+ Q++L+ D EL S
Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
L+ E+ EL + E + +IQ EE++ +E++ +K+ E E+
Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E M E + ++ EE M +E +++ + + + + K E+ K+ E E+ E+R
Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460
Query: 183 AE---LSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV-LSDKLKEAETR 238
E + E + RQ E++ ++ Q K E Q+E + +E K+ +K++E E R
Sbjct: 461 QEEEKIREQEKRQ-EQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR 519
Query: 239 AEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
E + + + E+ I + ++E++ QK K E++
Sbjct: 520 QE--QEEMWRQEEKIRE-QEEIWRQKEKIHEQEEKI 552
Score = 65.5 bits (158), Expect = 5e-11
Identities = 57/263 (21%), Positives = 122/263 (46%), Gaps = 23/263 (8%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
++ ++ E + E++ ++ E+++ ++ + E+++ + E + + +EK+ E+
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES------ERGMKVIESR 133
+ E + L ++ E+E R QE +K+ E EK ++ E ++ E +
Sbjct: 435 EKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQL 193
++ EEKM QE ++ E + I E+ R+ +E ++ R EE+ E RQ
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKRQEQE----------EMWRQEEKIREQEEIWRQK 542
Query: 194 EEQLRIMDQTLKALMAAEDKYSQKEDRY--EEEIKVLSDKLKEAETRAEFAERSVTKLEK 251
E +I +Q K E + Q+E + EE+I+ +K+ E + E + + E+
Sbjct: 543 E---KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Query: 252 SIDDLEDELYAQKLKYKAISEEL 274
I + E+ Q+ K E++
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKM 622
Score = 63.2 bits (152), Expect = 3e-10
Identities = 56/274 (20%), Positives = 125/274 (45%), Gaps = 28/274 (10%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLEL 73
++E + R E+ +K E++ ++ E+ + ++K++ E+ + + E +++ +EK+
Sbjct: 393 EQEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 449
Query: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER-------- 125
EK E R Q +E + R ++ E+ EK ++ E+
Sbjct: 450 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR--EQEEKIREQEEKMWRQEEKI 507
Query: 126 --GMKVIESRAQKDEEKMEIQEIQLKEAK---------HIAEDADRKYEE----VARKLV 170
K+ E ++++E+M QE +++E + H E+ RK EE K+
Sbjct: 508 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567
Query: 171 IIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSD 230
E + EE+ E ++R+ EE++R ++ ++ + +K EE++ +
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 231 KLKEAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
K++E E + E + + EK I + E+++ Q+
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661
Score = 28.5 bits (62), Expect = 7.0
Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 16/175 (9%)
Query: 108 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQ-----EIQLKEAKHIAED---AD 159
T KL EA++ + A D +K +I E H ED A
Sbjct: 116 TRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKAS 175
Query: 160 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA-AEDKYSQKE 218
+++E R+ +LE + Q +L+ L +K L A D S+
Sbjct: 176 HQHQEALRR------ELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 229
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 273
D ++ + L L T+ + A+R + +L K D L ELY + + + E+
Sbjct: 230 DSWKFAGE-LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 283
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 78.6 bits (192), Expect = 6e-15
Identities = 66/284 (23%), Positives = 139/284 (48%), Gaps = 15/284 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ ++++ +M+ +E + E+ +K E K+ E+E + Q+K + E ++ +
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ EKK E ++ + ++ EEE + QE + +K+ E E+
Sbjct: 437 EKIREQEEKIREQEKKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK---YEEVARKLVIIESDLER 178
+ E+ M E + +K EEK+ QE +++E + + + K EE R+ + + E+
Sbjct: 494 QKEK-MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 179 AEERAELSEGQVRQLEE------QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSD 230
E+ ++ E + RQ +E + +I +Q K E Q+E R E+E K+ +
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 231 KLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
K++E E + + E + + E+ I + E+ Q+ K E++
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 656
Score = 72.0 bits (175), Expect = 6e-13
Identities = 51/249 (20%), Positives = 121/249 (48%), Gaps = 12/249 (4%)
Query: 23 EQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEK------ 76
EQ E +K E +Q E+++ ++K++ E+++ + E +++ +E EK
Sbjct: 500 EQEEKIRKQEEKVWRQ-EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 77 -----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
K + E + +I+ EE++ R +E++ +K +E E+ + E ++ E
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 132 SRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVR 191
+ Q+ EEK+ QE +++E + + ++ + K E K+ E ++ EE E ++R
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 192 QLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEK 251
+ E+++R ++ ++ + +K EE++ +K++E E + E + + E
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 252 SIDDLEDEL 260
+ E+++
Sbjct: 739 RLRQQEEKM 747
Score = 70.9 bits (172), Expect = 1e-12
Identities = 50/246 (20%), Positives = 127/246 (51%), Gaps = 11/246 (4%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEA---DVASLN 89
+++ + E+++ ++K+ E+++ + E +++ +EK+ E+K + E + ++
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 90 RRIQLVEEELDRAQE-RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQL 148
+ ++ EEE + QE ++ +K+ E E+ E ++ E + Q+ EEKM QE ++
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALM 208
+E + ++ + K E K+ E + EE+ E ++ + EE+++ ++T +
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET---MW 671
Query: 209 AAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYK 268
E+K ++E + E+ +K++E E + E + + E+ + + E+++ Q+ K +
Sbjct: 672 RQEEKIREQEKKIREQ----EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727
Query: 269 AISEEL 274
E++
Sbjct: 728 RQEEKM 733
Score = 70.9 bits (172), Expect = 1e-12
Identities = 49/236 (20%), Positives = 115/236 (48%), Gaps = 4/236 (1%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+ I+++ + ++ +E + E+ ++ + K E E + ++K + ED++ +
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +++ +EK+ E+K + E ++ EE++ +E++ +K+ E E+
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E + E + + EEKM QE +++E + + K E +K I E+ E
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK---IREQEEKIRE 693
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR-YEEEIKVLSDKLKEAE 236
+ E+ + Q ++ EQ M + + + E+K ++E++ +E+E+++ + K E
Sbjct: 694 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 70.1 bits (170), Expect = 2e-12
Identities = 62/250 (24%), Positives = 128/250 (51%), Gaps = 27/250 (10%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE----KKATDAEAD-----VAS 87
++L+++ LQ+KL+ E E + +K+ + KLE A+ ++ AEAD + S
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + ++ EEK
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIM 200
M QE + E E+ R+ EE+ + E + R EE E ++R+ EE +
Sbjct: 337 MRRQEEMMWE----KEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMMWEK 389
Query: 201 DQTLKAL---MAAEDKYSQKEDRYEEEIKVL-SDKLKEAETRAEFAERSVTKLEKSIDDL 256
++ ++ L M ++K ++E++ +EE K+ +K +E E + E + + E+ I +
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Query: 257 EDELYAQKLK 266
E +++ Q+ K
Sbjct: 450 EKKMWRQEEK 459
Score = 68.9 bits (167), Expect = 5e-12
Identities = 59/274 (21%), Positives = 140/274 (51%), Gaps = 32/274 (11%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
++ + + +KE + R E+ +K E++ ++ E+ + ++K++ E+++ + E ++
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIR 407
Query: 66 DAQEKLELAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ +EK + EK K + EA ++ EE++ +E++ +K+ E+
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEA-------KMWRQEEKIREQEEKIREQEKKMWRQEEKI 460
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
E E K+ E ++++E+M QE ++ E + I ++ +E+ E + + E
Sbjct: 461 HEQE---KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ--------EEKIRKQE 509
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV-LSDKLKEAETRA 239
E+ E ++R+ EE++R ++ + E+K ++E+ + EE K+ +K+ E E R
Sbjct: 510 EKVWRQEEKIREQEEKIREQEE---KMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 240 EFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 273
E E + + E+ I + E++++ Q+ K + E+
Sbjct: 567 E-QEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599
Score = 67.8 bits (164), Expect = 1e-11
Identities = 65/291 (22%), Positives = 140/291 (48%), Gaps = 35/291 (12%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEDELVSLQKKLKG 52
+++ K ++Q+ + + L+RA+ QAEAD L EL S+ KL+
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD---------HLGKELQSVSAKLQA 283
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+E + ++ + +EK+ E+K + E + +I+ EE++ +E++ +
Sbjct: 284 QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
+ E E+ E M E + ++ EE M +E +++ + + + + K E+ K+
Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 403
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVL---- 228
E E+ E+R E E ++R+ E++ +Q K + E+K ++E++ E+ K +
Sbjct: 404 EKIREQEEKRQE--EEKIREQEKR---QEQEAK-MWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 229 -----SDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+K++E E R E + + + E+ I + ++E++ QK K E++
Sbjct: 458 EKIHEQEKIREEEKRQE--QEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKI 505
Score = 57.4 bits (137), Expect = 1e-08
Identities = 60/314 (19%), Positives = 143/314 (45%), Gaps = 41/314 (13%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADK--------KAAEDRSKQLEDELVSLQKKLKG 52
+ ++ K+Q ++++ +R Q + +K + E++ ++ E+++ ++K++
Sbjct: 274 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 53 TEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
E+++ + E + + +EK+ E+ + E + + EE++ R +E + +K
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Query: 113 LEEAEKAADESERGMKVIESRAQ----KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 168
+ E E+ E E+ + E R + +++EK + QE ++ + + + K E +K
Sbjct: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
Query: 169 L-----VIIESDLERAEERAELSEGQVRQLEE---------QLRIMDQTLKALMAAEDKY 214
+ I E + R EE+ + E RQ E+ Q M + + + E+K
Sbjct: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 215 SQKEDRY---EEEIKVLSDKLKEAETRAEFAE---RSVTKL--------EKSIDDLEDEL 260
++E++ EE+I+ +K+ E + E R K+ E+ + ED++
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 261 YAQKLKYKAISEEL 274
+ Q+ K + E++
Sbjct: 573 WRQEEKIREQEEKV 586
Score = 56.2 bits (134), Expect = 3e-08
Identities = 67/280 (23%), Positives = 131/280 (46%), Gaps = 34/280 (12%)
Query: 19 LDRAEQAEADKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
L++A A A +K DR ++L E +L +L ++ E QEKL+L E +
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 236
Query: 78 ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE-EAEKAADESERGMKVIESRA-- 134
++ + +V L R +L+RA +L Q+L+ EA+ E + ++++
Sbjct: 237 KSEIQLNVKELKR-------KLERA--KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
Query: 135 --------QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
Q+ EEKM QE +++E + ++ + K E K+ E + R EE
Sbjct: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK 347
Query: 187 EGQVRQLEEQLRIMDQTLK----ALMAAEDKYSQKED---RYEEEIKVLSDKLKEAETRA 239
E ++R+ EE + ++ ++ + E+K ++E+ EE+I+ L +K+ E E
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 407
Query: 240 EFAER-----SVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
E E+ + + EK + E +++ Q+ K + E++
Sbjct: 408 EQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKI 446
Score = 28.5 bits (62), Expect = 7.0
Identities = 40/175 (22%), Positives = 67/175 (38%), Gaps = 16/175 (9%)
Query: 108 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQ-----EIQLKEAKHIAED---AD 159
T KL EA++ + A D +K +I E H ED A
Sbjct: 55 TRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKAS 114
Query: 160 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA-AEDKYSQKE 218
+++E R+ +LE + Q +L+ L +K L A D S+
Sbjct: 115 HQHQEALRR------ELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 168
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 273
D ++ + L L T+ + A+R + +L K D L ELY + + + E+
Sbjct: 169 DSWKFAGE-LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 78.6 bits (192), Expect = 6e-15
Identities = 61/277 (22%), Positives = 131/277 (47%), Gaps = 15/277 (5%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
+++ + +E L +A++ E K+ E QL++EL + ++ + + E D+ ++ +
Sbjct: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
++ K LA ++ EA +A L EEEL+ Q +L++A D+
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQL-------EEELEEEQGNTELINDRLKKANLQIDQINT 1764
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR-KLVIIESDLERAEERAE 184
+ + S AQK+E + E Q KE K ++ + + + + +E+ + + EE+ +
Sbjct: 1765 DLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
Query: 185 LSEGQVRQLEEQLRIMDQTLKALMAAED-------KYSQKEDRYEEEIKVLSDKLKEAET 237
+ + +Q+R ++ LK ++ D +Y + D+ +K L +L+EAE
Sbjct: 1825 NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884
Query: 238 RAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
A+ A S KL++ ++D + A + ++ +L
Sbjct: 1885 EAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 66.2 bits (160), Expect = 3e-11
Identities = 61/283 (21%), Positives = 126/283 (44%), Gaps = 38/283 (13%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEA-----------DKKAAEDRSKQLEDELVSLQKKL 50
++ ++K+Q+ K+ E L + E+ + +KK EDR + L ++K
Sbjct: 956 ESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015
Query: 51 KGTEDELDKYSEALKDAQEKLELAEKK--------------ATDAEADVASLNRRIQLVE 96
K +K+ + D +E+L EK+ +TD +A L +I ++
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK 1075
Query: 97 EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+L + +E L AL ++EE + + + ++ +ES+ + +E +E + +A+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKR 1135
Query: 157 DADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQ 216
D + E + +L E L+ + EL + E+++ I+ +TL E++
Sbjct: 1136 DLGEELEALKTEL---EDTLDSTAAQQELRS----KREQEVNILKKTL------EEEAKT 1182
Query: 217 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDE 259
E + +E + S ++E + E +R LEK+ LE+E
Sbjct: 1183 HEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENE 1225
Score = 65.1 bits (157), Expect = 7e-11
Identities = 64/291 (21%), Positives = 133/291 (45%), Gaps = 30/291 (10%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKK--AAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+K +Q+ + ++E E + +K AAE+R ++E L + +++L +
Sbjct: 834 VKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAET 893
Query: 62 EALKDAQE-------KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
E +A+E K + E+ D EA V R Q ++ E + Q+ + ++LE
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 115 EAEKAADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADRKY-------EE 164
E E A + + E++ +K EE+ +E Q +L + K + ED ++ EE
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 165 VARKLVII----ESDLERAEERAELSEGQVRQLEEQLRIMD-------QTLKALMAAEDK 213
++ L + E+ + EER E Q ++LE+ R ++ + L A +
Sbjct: 1014 KSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE 1073
Query: 214 YSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
+ + EEE++ +++E + A + + +LE I +L+++L +++
Sbjct: 1074 LKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Score = 62.8 bits (151), Expect = 3e-10
Identities = 74/302 (24%), Positives = 140/302 (46%), Gaps = 46/302 (15%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL----QKKLKGTEDELDK 59
++K + L+ E + E+ E + +A ED +LE L ++ ++ L+G +++ ++
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 60 YSEAL-----------KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
+ L +D +++ +A E D+ L I + D A ++L
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 109 ALQKLEEAEKAADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADRKYEEV 165
++++ + D++ + I ++A+++E+K ME + IQL+E AE A R+ ++
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQE 1702
Query: 166 ARKLV--IIESDLERA---EERAELSEGQVRQLEEQLR--------IMDQTLKALMA--- 209
+L I S + A EE+ L E ++ QLEE+L I D+ KA +
Sbjct: 1703 RDELADEIANSSGKGALALEEKRRL-EARIAQLEEELEEEQGNTELINDRLKKANLQIDQ 1761
Query: 210 ------AEDKYSQKED----RYEEEIKVLSDKLKEAE-TRAEFAERSVTKLEKSIDDLED 258
E ++QK + + E + K L KL+E E T + S+T LE I LE+
Sbjct: 1762 INTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821
Query: 259 EL 260
+L
Sbjct: 1822 QL 1823
Score = 61.6 bits (148), Expect = 7e-10
Identities = 62/266 (23%), Positives = 127/266 (47%), Gaps = 28/266 (10%)
Query: 12 KLDKE-NALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEK 70
KL K+ +AL+ Q + E+R K +SL KLK EDE + + E L++ +E
Sbjct: 1298 KLTKDFSALESQLQDTQELLQEENRQK------LSLSTKLKQVEDEKNSFREQLEEEEEA 1351
Query: 71 LELAEKKATDAEADVASLNRR-------IQLVEEELDRAQERLATALQKLEEAEKAADES 123
EK+ A VA + ++ ++ EE + Q+ L Q+ EE A D+
Sbjct: 1352 KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKL 1411
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
E+ ++R Q++ + + + +++ E +K++++ + I + + AEER
Sbjct: 1412 EK----TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISA--KYAEER- 1464
Query: 184 ELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIK-VLSDK------LKEAE 236
+ +E + R+ E + + + L+ M + + + ++ E++ ++S K + E E
Sbjct: 1465 DRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELE 1524
Query: 237 TRAEFAERSVTKLEKSIDDLEDELYA 262
E+ V +++ +++LEDEL A
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQA 1550
Score = 61.2 bits (147), Expect = 1e-09
Identities = 59/256 (23%), Positives = 118/256 (46%), Gaps = 20/256 (7%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ-EKLELAEKKATDAE--ADVASLN 89
E+ E+ELV +++K E+ L + EKL+L E+ + E A+ L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 149
R+ ++EL+ L ++EE E+ + K ++ Q+ EE++E +E +
Sbjct: 904 ARLTAKKQELEEICHDLEA---RVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA 209
+ + + K +++ + +I+E + + +L E ++ + L ++ K+L
Sbjct: 961 KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL-- 1018
Query: 210 AEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED---ELYAQ--- 263
++ ++++E I L ++L+ E + + E++ KLE DL D EL AQ
Sbjct: 1019 -----AKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE 1073
Query: 264 -KLKYKAISEELDHAL 278
K++ EEL AL
Sbjct: 1074 LKMQLAKKEEELQAAL 1089
Score = 61.2 bits (147), Expect = 1e-09
Identities = 64/254 (25%), Positives = 120/254 (47%), Gaps = 14/254 (5%)
Query: 11 LKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEK 70
L K+ + EA + E+R + L+ E +KK++ EL++ E + A++K
Sbjct: 906 LTAKKQELEEICHDLEARVEEEEERCQHLQAE----KKKMQQNIQELEEQLEEEESARQK 961
Query: 71 LELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
L+L EK T+A+ +I L ++ A+E+ + E +E E+ +
Sbjct: 962 LQL-EKVTTEAKLKKLE-EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL- 1018
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQV 190
K + K E L+E E ++ E+ RKL +DL +++ AEL + Q+
Sbjct: 1019 ----AKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDL--SDQIAEL-QAQI 1071
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
+L+ QL ++ L+A +A ++ + +++ ++I+ L ++ E + E S K E
Sbjct: 1072 AELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAE 1131
Query: 251 KSIDDLEDELYAQK 264
K DL +EL A K
Sbjct: 1132 KQKRDLGEELEALK 1145
Score = 60.8 bits (146), Expect = 1e-09
Identities = 70/301 (23%), Positives = 134/301 (44%), Gaps = 37/301 (12%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDEL--------------VSLQKKLKGTEDE-LDKY 60
E +R + +A+KK + ++LE++L V+ + KLK E+E +
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 61 SEALKDAQEKLELAEKKA------TDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+ K A+EK L ++ A T+ E SL + E + +ERL ++ +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 115 EAEKA-----ADESERGMKVIESRAQKDEEKMEI----QEIQLKEAKHIAEDAD-----R 160
E EK D ++ ++ E +AQ E KM++ +E+Q A+ E A +
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
K E+ ++ ++ DLE +E Q R L E+L + L+ + + + +
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 221 YEEEIKVLSDKL-KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALN 279
E+E+ +L L +EA+T + K +++++L ++L Q + KA E+ L
Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL-EQTKRVKANLEKAKQTLE 1223
Query: 280 D 280
+
Sbjct: 1224 N 1224
Score = 58.9 bits (141), Expect = 5e-09
Identities = 65/293 (22%), Positives = 144/293 (49%), Gaps = 41/293 (13%)
Query: 2 DAIKKKMQMLKLDK------ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED 55
+A+++K ++ +L+K E+ + + E + LE ++ ++ +L+ ED
Sbjct: 1487 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELED 1546
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
EL +A +DA+ +LE+ + +A A R +Q +E+ + +++L ++++E
Sbjct: 1547 EL----QATEDAKLRLEV------NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME- 1595
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
AE + +R M V A + + +M++++++ HI + A++ +E ++L +++
Sbjct: 1596 AELEDERKQRSMAV----AARKKLEMDLKDLEA----HI-DSANKNRDEAIKQLRKLQAQ 1646
Query: 176 L-----ERAEERAELSE--GQVRQLEEQLRIMD----QTLKALMAAEDKYSQKEDRYEEE 224
+ E + RA E Q ++ E++L+ M+ Q + L AAE Q + +E
Sbjct: 1647 MKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDE- 1705
Query: 225 IKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHA 277
L+D++ + + A +LE I LE+EL ++ + I++ L A
Sbjct: 1706 ---LADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Score = 55.5 bits (132), Expect = 5e-08
Identities = 58/279 (20%), Positives = 125/279 (44%), Gaps = 21/279 (7%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED-------- 55
+ K L+ ++ + ++ K + + KQ+EDE S +++L+ E+
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
Query: 56 ------ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA 109
++ + ++D+ LE AE+ + D+ L++R + D+ ++
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418
Query: 110 LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169
Q+L++ D + +E + +K ++ + E + AK+ AE+ DR E AR+
Sbjct: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQL--LAEEKTISAKY-AEERDRA-EAEAREK 1474
Query: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLS 229
L RA E A + ++ +L +Q R ++ LM+++D + E+ + L
Sbjct: 1475 ETKALSLARALEEAMEQKAELERLNKQFR---TEMEDLMSSKDDVGKSVHELEKSKRALE 1531
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYK 268
+++E +T+ E E + E + LE L A K +++
Sbjct: 1532 QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570
Score = 55.1 bits (131), Expect = 7e-08
Identities = 51/302 (16%), Positives = 139/302 (46%), Gaps = 19/302 (6%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
++ K ++Q D LD Q+ + + + + QL E ++ K D +
Sbjct: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + L A ++A + +A++ LN++ + E+L +++ + ++ +LE++++A
Sbjct: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
Query: 121 DESERGMKV----IESRAQKDEEKMEIQEIQL--------KEAKHIAEDADRKYEEVARK 168
++ MK +E Q E+ E+ L ++ + E ++ K +++ R+
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 169 LVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVL 228
+ +E++LE ++ ++ ++LE L+ ++ + + D+ ++ + + ++K
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDC 1650
Query: 229 SDKL-------KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
+L +E +A+ E+ + +E + L++EL A + + +E D +++
Sbjct: 1651 MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710
Query: 282 TS 283
+
Sbjct: 1711 AN 1712
Score = 54.3 bits (129), Expect = 1e-07
Identities = 63/305 (20%), Positives = 129/305 (42%), Gaps = 34/305 (11%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALK 65
K+ Q + + K+ + A+ EA + + Q +EL ++ K + L+K + L+
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Query: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELD---RAQERLATAL-QKLEEAEKAAD 121
+ + +L K + D ++++ +EL ER+ T L K+ + + D
Sbjct: 1224 NERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELD 1283
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ +S++ K + E QL++ + + ++ +R+ ++ KL +E + E
Sbjct: 1284 NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFRE 1343
Query: 182 RAELSEGQVRQLEEQL-----------RIMDQTLKALMAAED--KYSQKE-----DRYEE 223
+ E E LE+Q+ + M+ ++ L AE+ + QK+ R+EE
Sbjct: 1344 QLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEE 1403
Query: 224 EIKVLSDKLKEAETRAE-----------FAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
++ DKL++ +TR + +S LEK + L +K +E
Sbjct: 1404 KVAAY-DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAE 1462
Query: 273 ELDHA 277
E D A
Sbjct: 1463 ERDRA 1467
Score = 46.2 bits (108), Expect = 3e-05
Identities = 45/209 (21%), Positives = 97/209 (46%), Gaps = 22/209 (10%)
Query: 2 DAIKK-KMQMLKLDKENALDR--AEQAEADKKAAEDRSKQLEDEL--------------- 43
D +KK +Q+ +++ + L+R A++ E ++ E ++K+L+ +L
Sbjct: 1750 DRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASI 1809
Query: 44 VSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+L+ K+ E++LD ++ + A +++ EKK D V R + +++ D+A
Sbjct: 1810 TALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAS 1869
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY- 162
RL ++LEEAE+ A + + ++ + E + ++ K+ D +
Sbjct: 1870 TRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFV 1929
Query: 163 --EEVARKLVIIESDLERAEERAELSEGQ 189
+ARK SD E + +A+ +E +
Sbjct: 1930 VPRRMARKGAGDGSD-EEVDGKADGAEAK 1957
Score = 38.5 bits (88), Expect = 0.007
Identities = 43/187 (22%), Positives = 79/187 (42%), Gaps = 21/187 (11%)
Query: 96 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIA 155
EEE+ +E L K+ E + AA+ M+ ++S+ EK+++QE QL+ +
Sbjct: 844 EEEMMAKEEELV----KVREKQLAAENRLTEMETLQSQLMA--EKLQLQE-QLQAETELC 896
Query: 156 EDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYS 215
+A+ + K +E E R E E + + L+ + + M Q ++ L
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQEL-------- 948
Query: 216 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275
E++ EEE E T E + KLE+ LED+ + K + + +
Sbjct: 949 --EEQLEEEESARQKLQLEKVT----TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 276 HALNDMT 282
++T
Sbjct: 1003 EFTTNLT 1009
Score = 28.5 bits (62), Expect = 7.0
Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 17/135 (12%)
Query: 160 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMD-QTLKALMAAEDKYSQKE 218
R + +V L + + E + EL + + +QL + R+ + +TL++ + AE Q++
Sbjct: 829 RLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQ 888
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE----------DELYAQKLKYK 268
+ E E+ +++L+ T + +LE+ DLE L A+K K +
Sbjct: 889 LQAETELCAEAEELRARLTAKK------QELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 269 AISEELDHALNDMTS 283
+EL+ L + S
Sbjct: 943 QNIQELEEQLEEEES 957
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 78.6 bits (192), Expect = 6e-15
Identities = 69/264 (26%), Positives = 126/264 (47%), Gaps = 23/264 (8%)
Query: 9 QMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ 68
QML L +R + E + E+R ++ E+ L +++L+ E+ L + E L + +
Sbjct: 188 QMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE 247
Query: 69 EKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK 128
E+L E++ + E + R++ EE L +ERL ++L E E+ E E ++
Sbjct: 248 ERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLR 307
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEG 188
E R + EE++ QE +L E + + +R EEV + L + ER +E E
Sbjct: 308 EQEERLCEQEERLREQEERLCEQEKL-PGQERLLEEVEKLL-----EQERRQEEQERLLE 361
Query: 189 QVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE-EEIKVLSDKL---------KEAETR 238
+ R LEE +++Q + L +++ Q+E E E ++ L L + AE R
Sbjct: 362 RERLLEEVEELLEQ--ERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPR 419
Query: 239 AEFAE-----RSVTKLEKSIDDLE 257
+ F E +S +LE+ + +L+
Sbjct: 420 SGFEELNNENKSTLQLEQQVKELK 443
Score = 75.9 bits (185), Expect = 4e-14
Identities = 66/274 (24%), Positives = 135/274 (49%), Gaps = 16/274 (5%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++K+++ + + ++ + + E+R ++ E+ L +++L+ E+ L + E
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEER 228
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
L++ +E+L E++ + E + R+ EE L +ERL ++L E E+ E
Sbjct: 229 LREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQ 288
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQL-KEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E ++ E R + EE++ QE +L ++ + + E +R E+ KL E LE E+
Sbjct: 289 EERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ--EKLPGQERLLEEVEKL 346
Query: 183 AELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFA 242
E Q R+ EEQ R++++ + L E+ Q+ R ++E + L+E E E
Sbjct: 347 LE----QERRQEEQERLLERE-RLLEEVEELLEQERLRQQDERLWQQETLQELERLRE-- 399
Query: 243 ERSVTKLEKSIDDLEDELYAQKLKYKAISEELDH 276
LE+ ++ + LY Q+ + ++ EEL++
Sbjct: 400 ------LERMLELGWEALYEQRAEPRSGFEELNN 427
Score = 68.2 bits (165), Expect = 8e-12
Identities = 65/260 (25%), Positives = 116/260 (44%), Gaps = 20/260 (7%)
Query: 10 MLKLDKENALDRAEQAEADKKAAE---DRSKQLEDELVSLQKKLKGTEDELDKYSEALKD 66
+ KL + A A + A E D + L EL S+ ++L+ + S +
Sbjct: 137 LFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRR 196
Query: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
+E+L E++ + E + R+ EE L +ERL ++L E E+ E E
Sbjct: 197 QEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEER 256
Query: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
+ E R + EE++ QE +L E + + + + E +L E L EER
Sbjct: 257 LCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ 316
Query: 187 EGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 246
E ++R+ EE+L E + ++R EE+ +KL E E R E ER +
Sbjct: 317 EERLREQEERL------------CEQEKLPGQERLLEEV----EKLLEQERRQEEQERLL 360
Query: 247 TKLEKSIDDLEDELYAQKLK 266
+ E+ ++++E+ L ++L+
Sbjct: 361 ER-ERLLEEVEELLEQERLR 379
Score = 37.4 bits (85), Expect = 0.015
Identities = 47/218 (21%), Positives = 94/218 (43%), Gaps = 30/218 (13%)
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
D+ + R E+L+ + LA AL E+ + R K+E+
Sbjct: 68 DSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLV----RTSKEEK 123
Query: 140 KMEIQEIQL----------KEAKHIAED---ADRKYEEVARKLVIIESDLERA--EERAE 184
K EI +Q + A+ +A + K E++ + + +LE + +AE
Sbjct: 124 KHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAE 183
Query: 185 LSEGQV-----RQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAE 236
+ Q+ R+ EE+LR ++ L+ E++ ++E+R EE ++ ++L+E E
Sbjct: 184 VENNQMLSLLNRRQEERLREQEERLR---EQEERLREQEERLCEQEERLREQEERLREQE 240
Query: 237 TRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
R E + + E+ + + E+ L Q+ + + E L
Sbjct: 241 ERLCEQEERLREHEERLCEQEERLCEQEERLREQEERL 278
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 78.6 bits (192), Expect = 6e-15
Identities = 59/276 (21%), Positives = 135/276 (48%), Gaps = 10/276 (3%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKD 66
+ Q L KE ++ + E ++K E K + E + Q+K ++++ + + + +
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
Query: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDR-----AQERLATALQKLEEAEKAAD 121
+EK+ E+K D E + + R++ EE + QE +K +E EK
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+ E M+ E R ++ E+KM +E ++E + ++ + K E K+ E ++ EE
Sbjct: 551 DQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAETR 238
+ E ++ + EE+ ++ +Q + + E+K ++E++ EE+++ +K++E E +
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQE-EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Query: 239 AEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+ E + + E+ + E+++ Q+ K + E++
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704
Score = 75.1 bits (183), Expect = 7e-14
Identities = 55/247 (22%), Positives = 125/247 (50%), Gaps = 16/247 (6%)
Query: 36 SKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLE-----LAEKKATDAEADVASLNR 90
+++L+ + LQ+KL+ E E + +K+ + KLE L + + + ++
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 91 RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKE 150
++ E+++ + +E++ ++L E E E E M+ E R ++ E+++ QE +L+E
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 151 AKHIAEDADRKYE------EVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTL 204
K + E ++ E E K+ E + R EER E Q+R+ E+++R ++ +
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
Query: 205 ----KALMAAEDKYSQKEDRYEEEIKVL-SDKLKEAETRAEFAERSVTKLEKSIDDLEDE 259
+ L E++ ++E +E+E K+ ++++E E + E ++ + E+ + E+
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 260 LYAQKLK 266
++ Q+ K
Sbjct: 422 MWEQEEK 428
Score = 72.4 bits (176), Expect = 4e-13
Identities = 52/235 (22%), Positives = 110/235 (46%), Gaps = 6/235 (2%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE 75
E ++ E+ KK + K E++ Q+K ++E + E +++ ++K+ E
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
+ + E + +++ EE++ +E++ +K+ E E+ E E K+ E
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
Query: 136 --KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQL 193
+ EEKM+ QE ++ E + + + K E K+ E + EE+ + E ++R+
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Query: 194 EEQLRIMDQTL----KALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
EE++R ++ + + + E+K +E+ E+E ++ K K E E ER
Sbjct: 694 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 70.1 bits (170), Expect = 2e-12
Identities = 57/258 (22%), Positives = 128/258 (49%), Gaps = 10/258 (3%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKD 66
K + +L ++ L +E++E E + K + + Q + ++E+ + E L++
Sbjct: 186 KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
Query: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
++K+ E+K E + +++ EE++ R ++RL ++L E EK E ++
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK- 304
Query: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
++ E + Q+ EEKM QE +++E + + + E +++ E + EER
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Query: 187 EGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 246
+ ++R+ EE++R ++ M +++ Q+E+R E K K++E E E +
Sbjct: 365 DERLREKEERMREQEK-----MWEQEEKMQEEERIREREK----KMREEEETMREQEEKM 415
Query: 247 TKLEKSIDDLEDELYAQK 264
K E+++ + E++ + Q+
Sbjct: 416 QKQEENMWEQEEKEWQQQ 433
Score = 67.0 bits (162), Expect = 2e-11
Identities = 55/272 (20%), Positives = 131/272 (48%), Gaps = 24/272 (8%)
Query: 15 KENALDRAEQAEADKKA-AEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLE- 72
+E D+ E +KK +++ ++ ED++ ++K++ E ++ E + + E+L
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 73 ----LAEKKATDAEADVASLNRRIQLVE------EELDRAQERLATALQKLEEAEKAADE 122
+ E+K + + ++ Q E EE R +ER+ +K+ E E+ E
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E M+ E + ++ EEKM QE +++E + + + K E + + ++ +E+
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE--------QEEEDKMQEQ 630
Query: 183 AELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFA 242
E+ Q +++EQ M + + + E+K ++E++ + + +K++E E + +
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ----EEKMREQEEKMQGQ 686
Query: 243 ERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
E + + E+ + E++++ Q+ K E++
Sbjct: 687 EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKM 718
Score = 65.9 bits (159), Expect = 4e-11
Identities = 62/258 (24%), Positives = 127/258 (49%), Gaps = 18/258 (6%)
Query: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRI 92
E + ++ E+++ +K+L+ E EL + + L++ Q+KL E++ + E + ++
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELRE-QKKLREQEEQMQEQEEKMWEQEEKM 326
Query: 93 QLVEEELDRAQERLATALQKLEEAE-KAADESERGMKVIESRAQKDE-----EKMEIQEI 146
+ EE++ R +ERL +++ E E K D+ ER + E +K+E EKM QE
Sbjct: 327 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE 386
Query: 147 QLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE---RAELSEGQVRQLEEQ------L 197
+++E + I E ++K E + E +++ EE E E Q ++L EQ
Sbjct: 387 KMQEEERIRE-REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 445
Query: 198 RIMDQTLKALMAAEDKYSQKEDRYEEEIKV-LSDKLKEAETRAEFAERSVTKLEKSIDDL 256
M + + + E+K +E+ + +E K+ +K++E E + E + E+ + D
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 257 EDELYAQKLKYKAISEEL 274
E+ ++ Q + + E +
Sbjct: 506 EERMWEQDERLREKEERM 523
Score = 65.9 bits (159), Expect = 4e-11
Identities = 53/225 (23%), Positives = 109/225 (48%), Gaps = 12/225 (5%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
++KM+ K +E +Q E K E+R ++ E ++ ++ ++ E+++ + E +
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEE--KMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 65 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEE--LDRAQERLATALQKLEEAEKAADE 122
++ +EK+ E+K + E + ++ EEE + +E + +K++E E+ E
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
E M+ E + ++ EEKM+ QE +++E + + + K E K+ E + EE+
Sbjct: 651 QEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Query: 183 ----AELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEE 223
E GQ E++ RI DQ K +++ + E+R E
Sbjct: 711 MWGQEEKMWGQEEMREKEERIRDQKEK----MQERLPEHEERCSE 751
Score = 61.2 bits (147), Expect = 1e-09
Identities = 51/246 (20%), Positives = 118/246 (47%), Gaps = 10/246 (4%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQA-EADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
D + ++ + ++ ++ D+ E+ E D++ E + E + + Q++ E + +
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ D +EK+ E++ + E + ++ EE++ +E++ +K+ E E+
Sbjct: 546 EKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM 604
Query: 121 DESERGMKVIESR--AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER 178
E E M E + Q++E+KM+ QE + E + ++ + K E K+ E +
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664
Query: 179 AEERAELSEGQVRQLEEQL-----RIMDQTLKALMAAEDKYSQKEDRYEEEIKVL-SDKL 232
EE+ + E ++R+ EE++ ++ +Q K E + Q+E + +E K+ +++
Sbjct: 665 QEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEM 724
Query: 233 KEAETR 238
+E E R
Sbjct: 725 REKEER 730
Score = 60.8 bits (146), Expect = 1e-09
Identities = 59/283 (20%), Positives = 139/283 (49%), Gaps = 18/283 (6%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE-----DELVSLQKKLKGTEDELDK 59
++KMQ + +E E+ E ++ E KQ E +E Q++L +++L +
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 444
Query: 60 YSEALKDAQEKLELAEKKATDAEADVASLNR-----RIQLVEEELDRAQERLATALQKLE 114
E +++ +EK+ E+K D E + +++ E+++ +E++ QK+
Sbjct: 445 -QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY--EEVARKLVII 172
+ E+ E + ++ E R ++++KM QE +++E K E + + EE R+ +
Sbjct: 504 DQEERMWEQDERLREKEER-MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 173 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR-YEEEIKVLSDK 231
++ E E+ Q +++EQ M + + + E+K ++E++ +E+E K+
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE-- 620
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
+E E + + E + + E+ + + E++++ Q+ K + E++
Sbjct: 621 -QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
Score = 55.1 bits (131), Expect = 7e-08
Identities = 56/267 (20%), Positives = 125/267 (46%), Gaps = 19/267 (7%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS-----EALKDAQEKLELA 74
+R + E + E + + E+ + ++L+ E+ + + E +E++
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 75 EKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM----KVI 130
EKK + E + ++Q EE + +E+ Q+L E ++ E E+ K+
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 131 ESRAQ-KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ 189
E + +D+E+M QE ++ + + E D+ +E+ K+ E + EER + +
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ-EEKMRDQEQKMWDQEERMWEQDER 515
Query: 190 VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVT 247
+R+ EE++R K + E+K +++ E+E K +K++E E E E+ +
Sbjct: 516 LREKEERMR----EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRE-REKKMR 570
Query: 248 KLEKSIDDLEDELYAQKLKYKAISEEL 274
+ E+ + + E+++ Q+ K + E++
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKM 597
Score = 50.8 bits (120), Expect = 1e-06
Identities = 34/183 (18%), Positives = 92/183 (50%), Gaps = 5/183 (2%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAA---EDRSKQLEDELVSLQKKL--KGTEDELD 58
++++ +M++ +E ++ E+ ++ E++ ++ E+++ ++K+ + ED++
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 59 KYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
+ E + + +EK++ E+K + E + +++ EE++ +E++ +K++ E+
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 119 AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER 178
E E M+ E + EEKM QE ++ + + E +R ++ + + ER
Sbjct: 689 KMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Query: 179 AEE 181
E
Sbjct: 749 CSE 751
Score = 33.9 bits (76), Expect = 0.17
Identities = 46/222 (20%), Positives = 93/222 (41%), Gaps = 26/222 (11%)
Query: 65 KDAQEKLELAEKKATD-AEADVASLNRRI-QLVEEELDRAQERLATALQKLEEAEKAADE 122
K Q KL A+KK TD + ++A + R +++++ T + E
Sbjct: 16 KTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKKA 75
Query: 123 SERGMKVIESRAQKDEEKMEI---QEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
S + + + + + + I Q+ +L+ A + ++DA RK+E + +L +
Sbjct: 76 SHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFE---------DGNLGES 126
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEI----KVLSDKLKEA 235
++ A +L + +AL +A + +K DRY EE+ LS +L
Sbjct: 127 KDLA-------GRLHHSWHFAGELQRAL-SAVSTWHKKADRYIEELTKERDALSLELYRN 178
Query: 236 ETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHA 277
E ++ +L++ + E E +L K + +L+ A
Sbjct: 179 TITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERA 220
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 77.0 bits (188), Expect = 2e-14
Identities = 70/326 (21%), Positives = 150/326 (46%), Gaps = 49/326 (15%)
Query: 1 MDAIKKKMQMLKLDKEN---ALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL 57
M ++K++++ L+ D N AL E+A A+K+ +R K+ D + + ++E+
Sbjct: 594 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 647
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASL--------------NRRIQLVEEELDRAQ 103
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 648 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 707
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQ---------KDEEKMEIQEIQ-----LK 149
E +L++A +AA E+ R + R Q KDE E+ LK
Sbjct: 708 EECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLK---- 205
E ++ D D+K E+ R++ + + + ++ + + Q+ E+ R + L
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ 826
Query: 206 ----ALMAAEDKYSQKEDRYEEEIKVLSDK---LKEAETRAEFAERSVTKLEKSIDDLED 258
+L +D+ + E+ E +++ +++ L + E+ AE+ V +L +++ ++
Sbjct: 827 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 886
Query: 259 ELYAQKLKYKAISEELDHALNDMTSM 284
EL + K K + + L +T++
Sbjct: 887 ELESMKAKLSSTQQSLAEKETHLTNL 912
Score = 65.5 bits (158), Expect = 5e-11
Identities = 65/292 (22%), Positives = 135/292 (46%), Gaps = 25/292 (8%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAA---EDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+KK + LK+ E+ L +A +A + +A+ DR + LE E+ + + + E+D+
Sbjct: 705 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E LK+ + + +KK + E V N+++ ++ + Q + Q LEEA + D
Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKH---KEQVEKKKSAQMLEEARRRED 819
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR--KYEEVAR-----KLVIIES 174
+ ++ +K ++++E E L+E+ I + + EE AR ++ +
Sbjct: 820 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 879
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQK--EDRYEEEIKVLSDK- 231
+E+ ++ E + ++ ++ L + L L A K+ ++ E + E + +S+K
Sbjct: 880 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD 939
Query: 232 ----LKEAETRAEFAERSVTKLEKSIDDLEDELYAQ---KLKYKAISEELDH 276
L E + + + V L++ D L +L Q ++K A + E DH
Sbjct: 940 ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDH 991
Score = 58.9 bits (141), Expect = 5e-09
Identities = 55/275 (20%), Positives = 121/275 (44%), Gaps = 16/275 (5%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++K ML + D AE+ D L+D L ++K+ + +++ E
Sbjct: 531 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHD----LKDMLDVKERKVNVLQKKIENLQEQ 586
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEE---ELDRAQERLATALQKLE-EAEKA 119
L+D ++++ +++ +AD + + + +EE E +R ERL + E E ++
Sbjct: 587 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 646
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
D ++ +K ++ + + + +E L + K A + +L +E LE+
Sbjct: 647 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 706
Query: 180 EERAELSEGQVRQLEE---QLRI---MDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLK 233
+E E Q+++ E + R M ++ L +Y + + + E+ L + LK
Sbjct: 707 KEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 234 EAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYK 268
E E ++ + +LE+ + D ++ LK+K
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKV--ANLKHK 799
Score = 58.2 bits (139), Expect = 8e-09
Identities = 52/280 (18%), Positives = 122/280 (43%), Gaps = 25/280 (8%)
Query: 4 IKKKMQMLKL-------DKENALDRAEQAEADKKAAEDRSKQLEDELVS-------LQKK 49
+++++QMLK ++E + + E + K +++ +QL++EL S L+KK
Sbjct: 401 LEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKK 460
Query: 50 LKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA 109
G + E+ + + L +L + K + + I++++E L ++R A
Sbjct: 461 AAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAIL 520
Query: 110 LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169
+++ +E E + + Q E+ Q ++ + K + + +RK + +K+
Sbjct: 521 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKI 580
Query: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAA-----------EDKYSQKE 218
++ L E++ + +V+ L+ D L L A +++ + E
Sbjct: 581 ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDE 640
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLED 258
+EEI LK+ + + + +++ E S+ DL++
Sbjct: 641 REKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKE 680
Score = 41.6 bits (96), Expect = 8e-04
Identities = 54/271 (19%), Positives = 110/271 (40%), Gaps = 38/271 (14%)
Query: 12 KLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKL 71
+L KE AL + E ++ +++ + +++E +Q ++ +DEL ++ +L
Sbjct: 193 ELKKERALRKDEASKIT--IWKEQYRVVQEENQHMQMTIQALQDEL-----RIQRDLNQL 245
Query: 72 ELAEKKATDAEADVASLNRR-IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
+ + E VA L Q + E +R + L + LEE E + ++ +
Sbjct: 246 FQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ---TL 302
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQV 190
+R + ++ +E+ + + AK ED +R R+L E + E E E +
Sbjct: 303 NARDESIKKLLEMLQSKGLSAKATEEDHER-----TRRLAEAEMHVHHLESLLEQKEKEN 357
Query: 191 RQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
L E++ ++ D S K K +T E + ++ +E
Sbjct: 358 SMLREEMH-------------RRFENAPD---------SAKTKALQTVIEMKDSKISSME 395
Query: 251 KSIDDLEDELYAQKLKYKAISEELDHALNDM 281
+ + DLE+E+ K +EE + + M
Sbjct: 396 RGLRDLEEEIQMLKSNGALSTEEREEEMKQM 426
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 77.0 bits (188), Expect = 2e-14
Identities = 70/326 (21%), Positives = 150/326 (46%), Gaps = 49/326 (15%)
Query: 1 MDAIKKKMQMLKLDKEN---ALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDEL 57
M ++K++++ L+ D N AL E+A A+K+ +R K+ D + + ++E+
Sbjct: 566 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 619
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASL--------------NRRIQLVEEELDRAQ 103
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 620 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 679
Query: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQ---------KDEEKMEIQEIQ-----LK 149
E +L++A +AA E+ R + R Q KDE E+ LK
Sbjct: 680 EECLKMESQLKKAHEAALEA-RASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 738
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLK---- 205
E ++ D D+K E+ R++ + + + ++ + + Q+ E+ R + L
Sbjct: 739 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ 798
Query: 206 ----ALMAAEDKYSQKEDRYEEEIKVLSDK---LKEAETRAEFAERSVTKLEKSIDDLED 258
+L +D+ + E+ E +++ +++ L + E+ AE+ V +L +++ ++
Sbjct: 799 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 858
Query: 259 ELYAQKLKYKAISEELDHALNDMTSM 284
EL + K K + + L +T++
Sbjct: 859 ELESMKAKLSSTQQSLAEKETHLTNL 884
Score = 65.5 bits (158), Expect = 5e-11
Identities = 65/292 (22%), Positives = 135/292 (46%), Gaps = 25/292 (8%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAA---EDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+KK + LK+ E+ L +A +A + +A+ DR + LE E+ + + + E+D+
Sbjct: 677 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 734
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E LK+ + + +KK + E V N+++ ++ + Q + Q LEEA + D
Sbjct: 735 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKH---KEQVEKKKSAQMLEEARRRED 791
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR--KYEEVAR-----KLVIIES 174
+ ++ +K ++++E E L+E+ I + + EE AR ++ +
Sbjct: 792 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 851
Query: 175 DLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQK--EDRYEEEIKVLSDK- 231
+E+ ++ E + ++ ++ L + L L A K+ ++ E + E + +S+K
Sbjct: 852 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD 911
Query: 232 ----LKEAETRAEFAERSVTKLEKSIDDLEDELYAQ---KLKYKAISEELDH 276
L E + + + V L++ D L +L Q ++K A + E DH
Sbjct: 912 ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDH 963
Score = 58.9 bits (141), Expect = 5e-09
Identities = 55/275 (20%), Positives = 121/275 (44%), Gaps = 16/275 (5%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+++K ML + D AE+ D L+D L ++K+ + +++ E
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHD----LKDMLDVKERKVNVLQKKIENLQEQ 558
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEE---ELDRAQERLATALQKLE-EAEKA 119
L+D ++++ +++ +AD + + + +EE E +R ERL + E E ++
Sbjct: 559 LRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 618
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
D ++ +K ++ + + + +E L + K A + +L +E LE+
Sbjct: 619 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 678
Query: 180 EERAELSEGQVRQLEE---QLRI---MDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLK 233
+E E Q+++ E + R M ++ L +Y + + + E+ L + LK
Sbjct: 679 KEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 738
Query: 234 EAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYK 268
E E ++ + +LE+ + D ++ LK+K
Sbjct: 739 EVENEKNDKDKKIAELERQVKDQNKKV--ANLKHK 771
Score = 51.6 bits (122), Expect = 8e-07
Identities = 54/297 (18%), Positives = 132/297 (44%), Gaps = 38/297 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD--KYSE 62
+K+ ML+ + + A + A KA + + + ++ S+++ L+ E+E+ K +
Sbjct: 354 EKENSMLREEMHRRFENAPDS-AKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNG 412
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
AL + + E+ + + + + + +I V++EL R L KLE +
Sbjct: 413 ALSTEEREEEMKQMEVYRSHSKF--MKNKIGQVKQELSRKDTELLALQTKLETLTNQFSD 470
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQL---------------KEAKHIAEDADRKYEEVAR 167
S++ ++V++ E++ I + ++ K+ K I + A+ K + A
Sbjct: 471 SKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQ-AG 529
Query: 168 KLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKV 227
++ ++ L+ E + + + ++ L+EQLR ++ + +L +E +K
Sbjct: 530 EIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSL--------------KERVKS 575
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
L +T E ++ + E++I+ L+++ + + EE+D+ D+ +
Sbjct: 576 LQADTTNTDTALTTLEEALAEKERTIERLKEQ---RDRDEREKQEEIDNYKKDLKDL 629
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 76.6 bits (187), Expect = 2e-14
Identities = 71/281 (25%), Positives = 133/281 (47%), Gaps = 30/281 (10%)
Query: 3 AIKKKMQMLKLDKENALDR----AEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD 58
A++ ++Q LK E A + A+QA K+ A LED LQK L LD
Sbjct: 315 ALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLL-----LD 369
Query: 59 KY-SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
K ++ +++ Q +L++ +K+++ AE + S +R++ + EL A L+KLE ++
Sbjct: 370 KQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEA-------LRKLENSD 422
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
K E + K + + K + ++ + Q +E I + +E + L L+
Sbjct: 423 K---EKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLK 479
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+++E +L EG++ L ++ + D+TLK + + EEE + L +L+ T
Sbjct: 480 KSKEHEKLMEGELEALRQEFKKKDKTLK----------ENSRKLEEENENLRAELQCCST 529
Query: 238 RAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHAL 278
+ E + ++ I DL E+ QK ++ +LD AL
Sbjct: 530 QLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKAL 570
Score = 67.4 bits (163), Expect = 1e-11
Identities = 65/301 (21%), Positives = 138/301 (45%), Gaps = 36/301 (11%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D +K + L LDK+ A D ++ + + + + S E E S +K+++ EL S
Sbjct: 357 DTQRKLQKGLLLDKQKA-DTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL---S 412
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD---RAQERLATALQK-LEEAE 117
EAL+ KLE ++K+ + VA + ++ + + + R Q + L++ L+EA
Sbjct: 413 EALR----KLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEAT 468
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE----VARKLVIIE 173
K ++ +K + + E ++E + K+ ++ RK EE + +L
Sbjct: 469 KLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCS 528
Query: 174 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRY------------ 221
+ LE + + S+ ++ L +++ + ++L +L A DK QKE Y
Sbjct: 529 TQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDA 588
Query: 222 --------EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 273
++++ +KL + + ++S+T+ ++ LE+E+ A + + K ++ E
Sbjct: 589 LSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTE 648
Query: 274 L 274
L
Sbjct: 649 L 649
Score = 53.5 bits (127), Expect = 2e-07
Identities = 62/283 (21%), Positives = 115/283 (40%), Gaps = 66/283 (23%)
Query: 11 LKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE- 69
L+ D + A E K +++ K +E EL +L+++ K + L + S L++ E
Sbjct: 460 LEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENEN 519
Query: 70 ----------KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
+LE + K ++ + LN+ I L +E L Q +L ALQK
Sbjct: 520 LRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQK------- 572
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
EK +Q KEA Y+ ++RK + DL +A
Sbjct: 573 -------------------EKHYLQTTITKEA----------YDALSRKSAACQDDLTQA 603
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAE 236
E+ + + L++ +L ++K +Q E+ YEE +K L+ +L++
Sbjct: 604 LEKLNHVTSETKSLQQ----------SLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLR 653
Query: 237 TRAEFAERSVTKLEKSIDDLEDEL------YAQKLKYKAISEE 273
+ +E V +K ++++ ++ + LK A EE
Sbjct: 654 GFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEE 696
Score = 52.8 bits (125), Expect = 3e-07
Identities = 61/290 (21%), Positives = 127/290 (43%), Gaps = 30/290 (10%)
Query: 22 AEQAEADKKAAEDRSKQLEDELVSL---QKKLKGTEDELDKYSEALKDAQE---KLEL-- 73
+E+ E KK + +Q + + + + Q +K EL+ SE ++ + KLEL
Sbjct: 153 SEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDL 212
Query: 74 -AEKKATDA-----EADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 127
++ T A + D+ L R+Q ++ E Q+ + L+E ++ E E+ +
Sbjct: 213 HGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKL 272
Query: 128 KVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVI----IESDLERAEE 181
+++ K E+++E Q+ E + ++A D+ E + L +++ LE A++
Sbjct: 273 TQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQ 332
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
+ L+ Q Q +E+ + L+ K + + + I+ L +L+ + +
Sbjct: 333 QERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSM 392
Query: 242 AERSVTKLEKSIDDLEDELY----------AQKLKYKAISEELDHALNDM 281
AE+ T K +++L EL +K + + E D +NDM
Sbjct: 393 AEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDM 442
Score = 42.7 bits (99), Expect = 4e-04
Identities = 36/213 (16%), Positives = 97/213 (45%), Gaps = 13/213 (6%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEAL 64
KKK + LK + + E A+ + + + ++ + Q+ ++ E+ E+L
Sbjct: 500 KKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESL 559
Query: 65 KDAQEKLELAEKK------ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
Q +L+ A +K T + +L+R+ +++L +A E+L + + ++
Sbjct: 560 MSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQ 619
Query: 119 AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA-------DRKYEEVARKLVI 171
+ +++ +E EE+M+ +L++ + +++ D+K EE++ +++
Sbjct: 620 SLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQ 679
Query: 172 IESDLERAEERAELSEGQVRQLEEQLRIMDQTL 204
+ + + E Q+R+ +E++ + + L
Sbjct: 680 WQKQHQNDLKMLAAKEEQLREFQEEMAALKENL 712
Score = 38.1 bits (87), Expect = 0.009
Identities = 26/139 (18%), Positives = 64/139 (46%), Gaps = 7/139 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
DA+ +K + D AL++ ++ +K L+ L Q+K E+E+ Y
Sbjct: 587 DALSRKSAACQDDLTQALEKLNHVTSE-------TKSLQQSLTQTQEKKAQLEEEIIAYE 639
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +K +L ++E +V + +++++ + ++ + Q++ L+ L E+
Sbjct: 640 ERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLR 699
Query: 122 ESERGMKVIESRAQKDEEK 140
E + M ++ +D+++
Sbjct: 700 EFQEEMAALKENLLEDDKE 718
Score = 37.0 bits (84), Expect = 0.020
Identities = 50/216 (23%), Positives = 90/216 (41%), Gaps = 17/216 (7%)
Query: 69 EKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK 128
EKL LA+++ A +ASL R + L D+ Q L+ ++ LE K G+
Sbjct: 10 EKLHLAQEQLALAGDKIASLERSLNLYR---DKYQSSLSN-IELLECQVKMLQGELGGIM 65
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEG 188
E + D K+ I +H ++ ++ EV +K+ + ++ + S
Sbjct: 66 GQEPENKGDHSKVRIYTSPCMIQEH--QETQKRLSEVWQKVSQQDDLIQELRNKLACSNA 123
Query: 189 QVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTK 248
V + E+ L I Q A A +Y E+IK + LK + + + V +
Sbjct: 124 LVLEREKAL-IKLQADFASCTATHRYPPSSSEECEDIKKI---LKHLQEQKDSQCLHVEE 179
Query: 249 LEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
+ + DL EL +A+SE+ + + DM +
Sbjct: 180 YQNLVKDLRVEL-------EAVSEQKRNIMKDMMKL 208
Score = 31.6 bits (70), Expect = 0.83
Identities = 37/180 (20%), Positives = 76/180 (42%), Gaps = 24/180 (13%)
Query: 13 LDKENALDRAE----QAEADKKAAEDR-------SKQLEDEL----VSLQKKLKGTEDEL 57
L+KE AL + QA+ DK +++ +K+ D L + Q L ++L
Sbjct: 548 LNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKL 607
Query: 58 DKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
+ + K Q+ L ++K E ++ + R++ + EL + + + ++ +
Sbjct: 608 NHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFD 667
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
K +E + + + Q D + + +E QL+E + E A K ++E D E
Sbjct: 668 KKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQE---------EMAALKENLLEDDKE 718
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 76.6 bits (187), Expect = 2e-14
Identities = 71/281 (25%), Positives = 133/281 (47%), Gaps = 30/281 (10%)
Query: 3 AIKKKMQMLKLDKENALDR----AEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELD 58
A++ ++Q LK E A + A+QA K+ A LED LQK L LD
Sbjct: 460 ALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLL-----LD 514
Query: 59 KY-SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
K ++ +++ Q +L++ +K+++ AE + S +R++ + EL A L+KLE ++
Sbjct: 515 KQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEA-------LRKLENSD 567
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLE 177
K E + K + + K + ++ + Q +E I + +E + L L+
Sbjct: 568 K---EKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLK 624
Query: 178 RAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAET 237
+++E +L EG++ L ++ + D+TLK + + EEE + L +L+ T
Sbjct: 625 KSKEHEKLMEGELEALRQEFKKKDKTLK----------ENSRKLEEENENLRAELQCCST 674
Query: 238 RAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHAL 278
+ E + ++ I DL E+ QK ++ +LD AL
Sbjct: 675 QLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKAL 715
Score = 67.4 bits (163), Expect = 1e-11
Identities = 65/301 (21%), Positives = 138/301 (45%), Gaps = 36/301 (11%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
D +K + L LDK+ A D ++ + + + + S E E S +K+++ EL S
Sbjct: 502 DTQRKLQKGLLLDKQKA-DTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL---S 557
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD---RAQERLATALQK-LEEAE 117
EAL+ KLE ++K+ + VA + ++ + + + R Q + L++ L+EA
Sbjct: 558 EALR----KLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEAT 613
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE----VARKLVIIE 173
K ++ +K + + E ++E + K+ ++ RK EE + +L
Sbjct: 614 KLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCS 673
Query: 174 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRY------------ 221
+ LE + + S+ ++ L +++ + ++L +L A DK QKE Y
Sbjct: 674 TQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDA 733
Query: 222 --------EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 273
++++ +KL + + ++S+T+ ++ LE+E+ A + + K ++ E
Sbjct: 734 LSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTE 793
Query: 274 L 274
L
Sbjct: 794 L 794
Score = 53.5 bits (127), Expect = 2e-07
Identities = 62/283 (21%), Positives = 115/283 (40%), Gaps = 66/283 (23%)
Query: 11 LKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE- 69
L+ D + A E K +++ K +E EL +L+++ K + L + S L++ E
Sbjct: 605 LEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENEN 664
Query: 70 ----------KLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
+LE + K ++ + LN+ I L +E L Q +L ALQK
Sbjct: 665 LRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQK------- 717
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
EK +Q KEA Y+ ++RK + DL +A
Sbjct: 718 -------------------EKHYLQTTITKEA----------YDALSRKSAACQDDLTQA 748
Query: 180 EERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR---YEEEIKVLSDKLKEAE 236
E+ + + L++ +L ++K +Q E+ YEE +K L+ +L++
Sbjct: 749 LEKLNHVTSETKSLQQ----------SLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLR 798
Query: 237 TRAEFAERSVTKLEKSIDDLEDEL------YAQKLKYKAISEE 273
+ +E V +K ++++ ++ + LK A EE
Sbjct: 799 GFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEE 841
Score = 52.8 bits (125), Expect = 3e-07
Identities = 61/290 (21%), Positives = 127/290 (43%), Gaps = 30/290 (10%)
Query: 22 AEQAEADKKAAEDRSKQLEDELVSL---QKKLKGTEDELDKYSEALKDAQE---KLEL-- 73
+E+ E KK + +Q + + + + Q +K EL+ SE ++ + KLEL
Sbjct: 298 SEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDL 357
Query: 74 -AEKKATDA-----EADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 127
++ T A + D+ L R+Q ++ E Q+ + L+E ++ E E+ +
Sbjct: 358 HGLREETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKL 417
Query: 128 KVIESRAQKDEEKMEIQEIQLKEAKHIAEDA--DRKYEEVARKLVI----IESDLERAEE 181
+++ K E+++E Q+ E + ++A D+ E + L +++ LE A++
Sbjct: 418 TQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQ 477
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
+ L+ Q Q +E+ + L+ K + + + I+ L +L+ + +
Sbjct: 478 QERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSM 537
Query: 242 AERSVTKLEKSIDDLEDELY----------AQKLKYKAISEELDHALNDM 281
AE+ T K +++L EL +K + + E D +NDM
Sbjct: 538 AEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDM 587
Score = 49.3 bits (116), Expect = 4e-06
Identities = 64/288 (22%), Positives = 122/288 (42%), Gaps = 21/288 (7%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
+ +KKK+ +L+ + E + + + + + ++ +LV L K EDE+ Y
Sbjct: 83 LQQLKKKLLVLQQELEFHTEELQTSYYSLRQYQSILEKQTSDLVLLHHHCKLKEDEVILY 142
Query: 61 SEAL----KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
E + ++ EKL LA+++ A +ASL R + L D+ Q L+ ++ LE
Sbjct: 143 EEEMGNHNENTGEKLHLAQEQLALAGDKIASLERSLNLYR---DKYQSSLSN-IELLECQ 198
Query: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDL 176
K G+ E + D K+ I +H ++ ++ EV +K+ + +
Sbjct: 199 VKMLQGELGGIMGQEPENKGDHSKVRIYTSPCMIQEH--QETQKRLSEVWQKVSQQDDLI 256
Query: 177 ERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAE 236
+ + S V + E+ L I Q A A +Y E+IK + LK +
Sbjct: 257 QELRNKLACSNALVLEREKAL-IKLQADFASCTATHRYPPSSSEECEDIKKI---LKHLQ 312
Query: 237 TRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
+ + V + + + DL EL +A+SE+ + + DM +
Sbjct: 313 EQKDSQCLHVEEYQNLVKDLRVEL-------EAVSEQKRNIMKDMMKL 353
Score = 42.0 bits (97), Expect = 6e-04
Identities = 52/263 (19%), Positives = 113/263 (42%), Gaps = 32/263 (12%)
Query: 28 DKKAAEDRS-KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELA-----EKKATDA 81
D+ DR L +L+SLQ +K D + + L+D Q +E A +KK A
Sbjct: 3 DEAGERDREVSSLNSKLLSLQLDIKNLHDVCKRQRKTLQDNQLCMEEAMNSSHDKKQAQA 62
Query: 82 EA-----------------DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
A + L +++ ++++EL+ E L T+ L + + ++
Sbjct: 63 LAFEESEVEFGSSKQCHLRQLQQLKKKLLVLQQELEFHTEELQTSYYSLRQYQSILEKQT 122
Query: 125 RGMKVIESRAQKDEEKMEIQEIQL-KEAKHIAEDADRKYEEVA---RKLVIIESDLERAE 180
+ ++ + E+++ + E ++ ++ E E++A K+ +E L
Sbjct: 123 SDLVLLHHHCKLKEDEVILYEEEMGNHNENTGEKLHLAQEQLALAGDKIASLERSLNLYR 182
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKE-AETRA 239
++ + S + LE Q++++ L +M E + K D + I ++E ET+
Sbjct: 183 DKYQSSLSNIELLECQVKMLQGELGGIMGQEPE--NKGDHSKVRIYTSPCMIQEHQETQK 240
Query: 240 EFAE--RSVTKLEKSIDDLEDEL 260
+E + V++ + I +L ++L
Sbjct: 241 RLSEVWQKVSQQDDLIQELRNKL 263
Score = 42.0 bits (97), Expect = 6e-04
Identities = 50/279 (17%), Positives = 117/279 (41%), Gaps = 20/279 (7%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
DA+ +K + D AL++ ++ +K L+ L Q+K E+E+ Y
Sbjct: 732 DALSRKSAACQDDLTQALEKLNHVTSE-------TKSLQQSLTQTQEKKAQLEEEIIAYE 784
Query: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +K +L ++E +V + +++++ + ++ + Q++ L+ L E+
Sbjct: 785 ERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLR 844
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E + M ++ +D+ +E + +D R Y + + +E + A++
Sbjct: 845 EFQEEMAALKENLLEDD-----KEPCCLPQWSVPKDTCRLYRGNDQIMTNLE---QWAKQ 896
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
+ +E QL EQ++ + L +D ++E K L +++E + +AE
Sbjct: 897 QKVANEKLGNQLREQVKY----IAKLSGEKDHLHSVMVHLQQENKKLKKEIEEKKMKAEN 952
Query: 242 AERSVTKLEKS-IDDLEDELYAQKLKYKAISEELDHALN 279
L S + + E L +K + +++ ++
Sbjct: 953 TRLCTKALGPSRTESTQREKVCGTLGWKGLPQDMGQRMD 991
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 76.6 bits (187), Expect = 2e-14
Identities = 68/288 (23%), Positives = 135/288 (46%), Gaps = 26/288 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
++ +M+ + + E+A ++ A K E ++K LE +L+ LQ+ L E A
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE-------RA 1702
Query: 64 LKDAQ-EKLELAEKKATDAEADVA------SLNRRIQLVEEELDRAQERLATALQKLEEA 116
K A EK ELAE+ A+ A L RI +EEEL+ Q + ++ +A
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 117 EKAADESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 173
+ A++ + S AQK+E +++E Q +L+ H E A + + + +E
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS--KFKSTIAALE 1820
Query: 174 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEE-------IK 226
+ + + EE+ E + + + L+ D+ LK ++ + + ++Y+E+ +K
Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880
Query: 227 VLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEEL 274
L +L+EAE ++ + KL++ +D+ + A + A+ +L
Sbjct: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 70.1 bits (170), Expect = 2e-12
Identities = 75/295 (25%), Positives = 136/295 (46%), Gaps = 32/295 (10%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEDELV-------SLQKK 49
+ A +KKM LD E L+ E A + +K AE + K+LEDE++ L K+
Sbjct: 941 LQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Query: 50 LKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA 109
K E+ + + L + +EK + K E+ ++ L R++ E ++++ L
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE----KSRQELEKL 1056
Query: 110 LQKLEEAEKAADESERGMKVIESRAQKDEEKMEI----QEIQLKEAK---HIAE--DADR 160
+KLE D S+ ++ + +AQ E KM++ +E+Q A+ IA+ +A +
Sbjct: 1057 KRKLE-----GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1111
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
K E+ + ++ DL+ +E Q R L E+L + L+ + + + +
Sbjct: 1112 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1171
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275
E+E+ VL L E ETR+ E V ++ + +EL Q ++K LD
Sbjct: 1172 REQEVTVLKKALDE-ETRSH--EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223
Score = 66.6 bits (161), Expect = 2e-11
Identities = 67/295 (22%), Positives = 133/295 (45%), Gaps = 27/295 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSL---------------QK 48
++K + L+ E + E+ E + +A ED +LE + +L ++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 49 KLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRR----IQLVEE---ELDR 101
K + + +L +Y L+D +++ LA E D+ L + I+ EE +L +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1708
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDR 220
+ EE+A +L S ++ E ++ QLEE+L ++A+ K +Q+ ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275
E+ ++ E+ + ER +L + ++E A K K+K+ L+
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG---AVKSKFKSTIAALE 1820
Score = 66.6 bits (161), Expect = 2e-11
Identities = 50/239 (20%), Positives = 119/239 (49%), Gaps = 15/239 (6%)
Query: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
A ++ + L+KE + + + + A +D ++LE + L+++L+ + ++ S+
Sbjct: 1698 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757
Query: 63 ALKDAQEKLE-LAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
++ A ++ E L+ + AT+ S ++ + ++L+R + L + L ++E A K+
Sbjct: 1758 RVRKATQQAEQLSNELATER-----STAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1812
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
+S + +E++ + EE++E + + + A + D+K +E+ ++ E+ +E
Sbjct: 1813 KST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1870
Query: 182 RAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEE-------EIKVLSDKLK 233
+AE +V+QL+ QL ++ + + A K ++ D E E+ L KL+
Sbjct: 1871 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 63.5 bits (153), Expect = 2e-10
Identities = 58/237 (24%), Positives = 114/237 (48%), Gaps = 41/237 (17%)
Query: 47 QKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE-- 104
+++++ EDEL K E + A+ +L+ E+K + + L ++Q E A+E
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 105 -RLATALQKLEEA-----EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158
RLA Q+LEE + +E +RG ++ R + ++ ++++E QL+E
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEE-------- 961
Query: 159 DRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKE 218
EE AR+ + +E +E ++++LE+++ +MD +K S++
Sbjct: 962 ----EEAARQKLQLEK---------VTAEAKIKKLEDEILVMDD-------QNNKLSKER 1001
Query: 219 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275
EE I L+ L E E +A +++TKL+ + + EL + K + +EL+
Sbjct: 1002 KLLEERISDLTTNLAEEEEKA----KNLTKLKNKHESMISELEVRLKKEEKSRQELE 1054
Score = 62.4 bits (150), Expect = 4e-10
Identities = 69/295 (23%), Positives = 132/295 (44%), Gaps = 27/295 (9%)
Query: 2 DAIKKKMQMLKLDKE---NALDRAEQAEADKKA---AEDRSKQLEDELVSLQKKLKGTED 55
D I +K LK +E + D E ++++ A AE + + L +EL +L+ +L+ T D
Sbjct: 1101 DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1160
Query: 56 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E L+ +E+ KKA D E S ++Q + ++ +A E L L++ +
Sbjct: 1161 STATQQE-LRAKREQEVTVLKKALDEET--RSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
Query: 116 AEKAADESERGM-----------KVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 164
A+ D++++ + +V+ Q+ E K + E Q++E + D +R E
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277
Query: 165 VARKLVIIESDLERAEERAELSEGQ-------VRQLEEQLRIMDQTLKALMAAEDKYSQK 217
+ K+ +++++E +EG+ V L QL+ + L+ + S K
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337
Query: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISE 272
+ EEE L D+L E + ER ++ L + D + +L +A+ E
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392
Score = 62.0 bits (149), Expect = 6e-10
Identities = 66/277 (23%), Positives = 128/277 (46%), Gaps = 26/277 (9%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTED---ELDKY 60
+K +M+ L K++ + E K+A E + ++++ +L L+ +L+ TED L+
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ALK E+ + +A D + + + QL E E + ER AL A A
Sbjct: 1569 MQALKGQFER----DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL-----AAAAK 1619
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ E +K +E +A + E QL++ + +D R+ E+ I + + E
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
++A+ E + QL+E L AA ++ ++ D +EE L+++L + +
Sbjct: 1680 KKAKSLEADLMQLQEDL-----------AAAERARKQADLEKEE---LAEELASSLSGRN 1725
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHA 277
+ +LE I LE+EL ++ +A+S+ + A
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Score = 61.6 bits (148), Expect = 7e-10
Identities = 52/264 (19%), Positives = 117/264 (44%), Gaps = 7/264 (2%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELA 74
K L + + E + +A ED ++ ++ + +LK E + + +E QE+L+
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 75 EKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
+ +AE L + Q +EE L + RL + ++ + A+ + ++++
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ--AERKKMAQQMLDLEE 957
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLE 194
Q +EE+ Q++QL++ A+ K +++ ++++++ + + +L E ++ L
Sbjct: 958 QLEEEEAARQKLQLEKV-----TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLT 1012
Query: 195 EQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 254
L ++ K L ++K+ E +K +E E E + + I
Sbjct: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1072
Query: 255 DLEDELYAQKLKYKAISEELDHAL 278
DL+ ++ K++ EEL AL
Sbjct: 1073 DLQAQIAELKMQLAKKEEELQAAL 1096
Score = 61.6 bits (148), Expect = 7e-10
Identities = 60/295 (20%), Positives = 135/295 (45%), Gaps = 36/295 (12%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTE 54
++++ LK + E+ LD R ++ KKA ++ ++ E ++ +++K
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 55 DELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+EL + E K A+ L+ ++ AD+A R + ++E++ +++L +Q+L+
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Query: 115 ----EAEKAAD-------------ESERGM-KVIESRAQKDEEKMEIQEIQLKEAKHIAE 156
+ E+A ES GM E +A K + + QL++ + + +
Sbjct: 1266 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1325
Query: 157 DADRKYEEVARKLVIIESD-------LERAEERAELSEGQVRQLEEQLRIMDQTLKALMA 209
+ R+ V+ KL +E + L+ E + E + L QL + L+ +
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1385
Query: 210 AEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQK 264
+ + + R+++EI+ L+ + +E + E++ +L++ +DDL +L Q+
Sbjct: 1386 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/271 (22%), Positives = 120/271 (44%), Gaps = 31/271 (11%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
+ K + L ++ + ++ K + +QLE+E SLQ D+LD+ EA
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-------DQLDEEMEA 1358
Query: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++ + + + +D++ + ++ +EE R Q+ + Q+ EE A D+
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES----DLERA 179
E+ ++R Q++ + + + ++ E RK++++ + I S + +RA
Sbjct: 1419 EK----TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 180 EERAELSEGQ----VRQLEEQLRI---MDQTLKALMA-AEDKYSQKEDRYEEEIKVLSDK 231
E A E + R LEE L +++T K L A ED S K+D +
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD--------VGKN 1526
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEDELYA 262
+ E E E + +++ +++LEDEL A
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQA 1557
Score = 59.7 bits (143), Expect = 3e-09
Identities = 73/290 (25%), Positives = 124/290 (42%), Gaps = 48/290 (16%)
Query: 13 LDKENALDRAEQAEA---DKKAAEDRSKQLEDELVSLQKKLKGTE-------DELDKYSE 62
L+KENA D A + K+ E + K+LE ++ LQ K E D++ K
Sbjct: 1229 LEKENA-DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD---RAQERLATALQKLEEAEKA 119
++ L AE KA DVASL+ ++Q +E L R + ++T L++LEE +
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 120 ADES-----------ERGMKVIESRAQKDEEKME--------IQEIQLKEAKHIAEDADR 160
+ ER + + + ++K++ ++E + + K I E+ +
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI-ENLTQ 1406
Query: 161 KYEEVARKLVIIESDLERAEERAE-------LSEGQVRQLEEQLRIMDQTLKALMAAEDK 213
+YEE A +E R ++ + V LE++ R DQ L K
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
Query: 214 YSQKEDRYEEEIK-------VLSDKLKEAETRAEFAERSVTKLEKSIDDL 256
Y+ + DR E E + L+ L+EA E ER+ L+ ++DL
Sbjct: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Score = 59.3 bits (142), Expect = 4e-09
Identities = 60/281 (21%), Positives = 136/281 (48%), Gaps = 12/281 (4%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA- 63
+++MQ + + + +R ++AE + K E + QL +E LQ++L+ E + Y+EA
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 907
Query: 64 ---LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
++ A +K EL E+ + EA + R Q ++ E + +++ ++LEE E A
Sbjct: 908 EMRVRLAAKKQEL-EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
+ + E++ +K E+++ + + Q + + + + ++ L E +
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
+ E + +LE +L+ +++ + L + K + E+I L ++ AE + +
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI--AELKMQ 1084
Query: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
A++ +L+ ++ L+DE+ AQK EL+ ++D+
Sbjct: 1085 LAKKE-EELQAALARLDDEI-AQKNNALKKIRELEGHISDL 1123
Score = 55.1 bits (131), Expect = 7e-08
Identities = 61/253 (24%), Positives = 110/253 (43%), Gaps = 18/253 (7%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAE 75
E +R +Q D D +QL L Q+K E S D +++ AE
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR---AE 1475
Query: 76 KKATDAEADVASLNRRIQLV---EEELDRAQERLATALQKL----EEAEKAADESERGMK 128
+A + E SL R ++ +EEL+R + L ++ L ++ K E E+ +
Sbjct: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1535
Query: 129 VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER-AEERAELSE 187
+E+ Q +E K +++E L++ EDA + E + ++ ER + R E +E
Sbjct: 1536 ALET--QMEEMKTQLEE--LEDELQATEDAKLRLEV---NMQALKGQFERDLQARDEQNE 1588
Query: 188 GQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
+ RQL+ QL + L+ + + + E ++K L + A E A + +
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 248 KLEKSIDDLEDEL 260
KL+ + D + EL
Sbjct: 1649 KLQAQMKDFQREL 1661
Score = 55.1 bits (131), Expect = 7e-08
Identities = 64/303 (21%), Positives = 135/303 (44%), Gaps = 42/303 (13%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61
+A +K+ + L L + AL+ A +A+ + + K ++LVS + + EL+K
Sbjct: 1477 EAREKETKALSLAR--ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 62 EALKDAQEKLELA------EKKATD----------------AEADVAS-----------L 88
AL+ E+++ E +AT+ E D+ + L
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 89 NRRIQLVEEEL--DRAQERLATALQK-----LEEAEKAADESERGMKVIESRAQKDEEKM 141
R++ E EL +R Q LA A +K L++ E AD + +G + + +K + +M
Sbjct: 1595 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1654
Query: 142 EIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMD 201
+ + +L++A+ ++ +E +K +E+DL + +E +E +Q + + +
Sbjct: 1655 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 202 QTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELY 261
+ L + ++ + ++ R E I L ++L+E + E V K + + L +EL
Sbjct: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1774
Query: 262 AQK 264
++
Sbjct: 1775 TER 1777
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 37 KQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAE---ADVASLNRRIQ 93
+Q+E E Q K + + K E L +++ ++AE+ AE A V L R+++
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1887
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 153
EEE R ++L+EA ++ + R + ++S+ ++ E + + +
Sbjct: 1888 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPS-RRSGGRR 1946
Query: 154 IAEDADRKYEE 164
+ E+AD EE
Sbjct: 1947 VIENADGSEEE 1957
Score = 39.3 bits (90), Expect = 0.004
Identities = 27/130 (20%), Positives = 58/130 (44%), Gaps = 10/130 (7%)
Query: 20 DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKAT 79
++ EQ +K+AA KQ + +L + +++ ++Y E + +++ +++
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1887
Query: 80 DAEADVASLNRRIQLVEEELDRAQE----------RLATALQKLEEAEKAADESERGMKV 129
+AE + +N + ++ ELD A E L + L++ E G +V
Sbjct: 1888 EAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRV 1947
Query: 130 IESRAQKDEE 139
IE+ +EE
Sbjct: 1948 IENADGSEEE 1957
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.122 0.294
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,237,336
Number of Sequences: 37866
Number of extensions: 380192
Number of successful extensions: 14879
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 693
Number of HSP's successfully gapped in prelim test: 1022
Number of HSP's that attempted gapping in prelim test: 3180
Number of HSP's gapped (non-prelim): 6101
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.