Guide to the Human Genome
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Name: HECW2 Sequence: fasta or formatted (1572aa) NCBI GI: 55741473
Description:

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2

Referenced in:

Ubiquitin and Related Protein Modifications
WW Domain

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6        104           5
 C cysteine            1.1         17           1
 D aspartate           5.4         85           2
 E glutamate           8.8        138           3
 F phenylalanine       4.3         67           3
 G glycine             6.6        104           2
 H histidine           2.9         46           2
 I isoleucine          3.9         61           2
 K lysine              3.1         49           2
 L leucine             8.3        130           3
 M methionine          1.9         30           2
 N asparagine          4.0         63           2
 P proline             6.5        102           2
 Q glutamine           4.7         74           2
 R arginine            7.1        112           3
 S serine             10.2        160           2
 T threonine           6.0         95           3
 V valine              4.9         77           2
 W tryptophan          1.0         16           1
 Y tyrosine            2.7         42           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   HECT, C2 and WW domain containing E3 ubiquitin prote... 
HECW1                 0.523   NEDD4-like ubiquitin-protein ligase 1 
NEDD4                 0.136   neural precursor cell expressed, developmentally do...
NEDD4                 0.136   neural precursor cell expressed, developmentally do...
NEDD4L                0.128   neural precursor cell expressed, developmentally dow...
NEDD4L                0.128   neural precursor cell expressed, developmentally do...
NEDD4L                0.128   neural precursor cell expressed, developmentally do...
NEDD4L                0.128   neural precursor cell expressed, developmentally do...
NEDD4L                0.119   neural precursor cell expressed, developmentally do...
NEDD4L                0.119   neural precursor cell expressed, developmentally do...
NEDD4L                0.119   neural precursor cell expressed, developmentally do...
NEDD4L                0.119   neural precursor cell expressed, developmentally do...
NEDD4L                0.119   neural precursor cell expressed, developmentally do...
WWP2                  0.112   WW domain containing E3 ubiquitin protein ligase 2 i...
WWP1                  0.112   WW domain containing E3 ubiquitin protein ligase 1 [...
ITCH                  0.111   itchy homolog E3 ubiquitin protein ligase 
WWP2                  0.107   WW domain containing E3 ubiquitin protein ligase 2 i...
SMURF2                0.107   SMAD specific E3 ubiquitin protein ligase 2 
SMURF1                0.106   Smad ubiquitination regulatory factor 1 isoform 1 [H...
SMURF1                0.106   Smad ubiquitination regulatory factor 1 isoform 2 [H...
HUWE1                 0.090   HECT, UBA and WWE domain containing 1 
HACE1                 0.076   HECT domain and ankyrin repeat containing, E3 ubiqu...
UBE3A                 0.052   ubiquitin protein ligase E3A isoform 3 
UBE3A                 0.052   ubiquitin protein ligase E3A isoform 1 
UBE3A                 0.052   ubiquitin protein ligase E3A isoform 2 
HERC3                 0.050   hect domain and RLD 3 
HECTD2                0.050   HECT domain containing 2 isoform a 
UBE3B                 0.050   ubiquitin protein ligase E3B 
UBE3B                 0.050   ubiquitin protein ligase E3B 
KIAA0317              0.049   hypothetical protein LOC9870 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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