Guide to the Human Genome
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Name: NEDD4L Sequence: fasta or formatted (854aa) NCBI GI: 222352082
Description:

neural precursor cell expressed, developmentally down-regulated 4-like isoform 2

Referenced in:

Sodium Channels
Ubiquitin and Related Protein Modifications
WW Domain

Other entries for this name:
alt prot [955aa] neural precursor cell expressed, developmentally down-regulated 4...
alt mRNA [854aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [975aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [967aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [947aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [834aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [834aa] neural precursor cell expressed, developmentally down-regulated 4...
alt mRNA [854aa] neural precursor cell expressed, developmentally down-regulated 4...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.2         36           2
 C cysteine            0.7          6           1
 D aspartate           5.6         48           2
 E glutamate           8.3         71           2
 F phenylalanine       4.4         38           2
 G glycine             6.0         51           2
 H histidine           2.6         22           1
 I isoleucine          4.2         36           1
 K lysine              4.7         40           2
 L leucine             8.7         74           2
 M methionine          2.5         21           2
 N asparagine          6.0         51           2
 P proline             8.5         73           4
 Q glutamine           4.0         34           1
 R arginine            7.0         60           2
 S serine              7.5         64           2
 T threonine           5.2         44           3
 V valine              4.6         39           2
 W tryptophan          2.1         18           1
 Y tyrosine            3.3         28           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   neural precursor cell expressed, developmentally do... 
NEDD4L                1.000   neural precursor cell expressed, developmentally do...
NEDD4L                1.000   neural precursor cell expressed, developmentally do...
NEDD4L                1.000   neural precursor cell expressed, developmentally do...
NEDD4L                1.000   neural precursor cell expressed, developmentally do...
NEDD4L                0.971   neural precursor cell expressed, developmentally dow...
NEDD4L                0.971   neural precursor cell expressed, developmentally do...
NEDD4L                0.971   neural precursor cell expressed, developmentally do...
NEDD4L                0.971   neural precursor cell expressed, developmentally do...
NEDD4                 0.588   neural precursor cell expressed, developmentally do...
NEDD4                 0.546   neural precursor cell expressed, developmentally do...
ITCH                  0.287   itchy homolog E3 ubiquitin protein ligase 
WWP1                  0.279   WW domain containing E3 ubiquitin protein ligase 1 [...
SMURF2                0.276   SMAD specific E3 ubiquitin protein ligase 2 
WWP2                  0.261   WW domain containing E3 ubiquitin protein ligase 2 i...
SMURF1                0.249   Smad ubiquitination regulatory factor 1 isoform 2 [H...
SMURF1                0.246   Smad ubiquitination regulatory factor 1 isoform 1 [H...
WWP2                  0.234   WW domain containing E3 ubiquitin protein ligase 2 i...
HECW2                 0.214   HECT, C2 and WW domain containing E3 ubiquitin prote...
HECW1                 0.201   NEDD4-like ubiquitin-protein ligase 1 
HUWE1                 0.181   HECT, UBA and WWE domain containing 1 
HACE1                 0.149   HECT domain and ankyrin repeat containing, E3 ubiqu...
KIAA0317              0.110   hypothetical protein LOC9870 
UBE3A                 0.102   ubiquitin protein ligase E3A isoform 3 
UBE3A                 0.102   ubiquitin protein ligase E3A isoform 1 
UBE3A                 0.102   ubiquitin protein ligase E3A isoform 2 
UBE3C                 0.092   ubiquitin protein ligase E3C 
HERC3                 0.091   hect domain and RLD 3 
HECTD2                0.091   HECT domain containing 2 isoform a 
HERC4                 0.087   hect domain and RLD 4 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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