Guide to the Human Genome
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Name: NEDD4L Sequence: fasta or formatted (967aa) NCBI GI: 222352088
Description:

neural precursor cell expressed, developmentally down-regulated 4-like isoform 4

Referenced in:

Sodium Channels
Ubiquitin and Related Protein Modifications
WW Domain

Other entries for this name:
alt prot [955aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [854aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [854aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [975aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [947aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [834aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [834aa] neural precursor cell expressed, developmentally down-regulated 4...
alt prot [854aa] neural precursor cell expressed, developmentally down-regulated 4...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.2         41           2
 C cysteine            0.6          6           1
 D aspartate           5.9         57           2
 E glutamate           8.3         80           2
 F phenylalanine       4.7         45           2
 G glycine             5.7         55           2
 H histidine           2.5         24           1
 I isoleucine          4.1         40           1
 K lysine              5.0         48           2
 L leucine             9.1         88           2
 M methionine          2.3         22           2
 N asparagine          5.9         57           2
 P proline             8.2         79           4
 Q glutamine           3.8         37           1
 R arginine            7.1         69           2
 S serine              7.2         70           2
 T threonine           5.2         50           3
 V valine              5.1         49           2
 W tryptophan          2.0         19           1
 Y tyrosine            3.2         31           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   neural precursor cell expressed, developmentally do... 
NEDD4L                0.993   neural precursor cell expressed, developmentally do...
NEDD4L                0.974   neural precursor cell expressed, developmentally do...
NEDD4L                0.968   neural precursor cell expressed, developmentally dow...
NEDD4L                0.886   neural precursor cell expressed, developmentally do...
NEDD4L                0.886   neural precursor cell expressed, developmentally do...
NEDD4L                0.886   neural precursor cell expressed, developmentally do...
NEDD4L                0.861   neural precursor cell expressed, developmentally do...
NEDD4L                0.861   neural precursor cell expressed, developmentally do...
NEDD4                 0.596   neural precursor cell expressed, developmentally do...
NEDD4                 0.484   neural precursor cell expressed, developmentally do...
ITCH                  0.255   itchy homolog E3 ubiquitin protein ligase 
WWP1                  0.251   WW domain containing E3 ubiquitin protein ligase 1 [...
SMURF2                0.245   SMAD specific E3 ubiquitin protein ligase 2 
WWP2                  0.231   WW domain containing E3 ubiquitin protein ligase 2 i...
SMURF1                0.221   Smad ubiquitination regulatory factor 1 isoform 2 [H...
SMURF1                0.218   Smad ubiquitination regulatory factor 1 isoform 1 [H...
WWP2                  0.207   WW domain containing E3 ubiquitin protein ligase 2 i...
HECW2                 0.189   HECT, C2 and WW domain containing E3 ubiquitin prote...
HECW1                 0.178   NEDD4-like ubiquitin-protein ligase 1 
HUWE1                 0.161   HECT, UBA and WWE domain containing 1 
HACE1                 0.132   HECT domain and ankyrin repeat containing, E3 ubiqu...
KIAA0317              0.098   hypothetical protein LOC9870 
UBE3A                 0.090   ubiquitin protein ligase E3A isoform 3 
UBE3A                 0.090   ubiquitin protein ligase E3A isoform 1 
UBE3A                 0.090   ubiquitin protein ligase E3A isoform 2 
UBE3C                 0.082   ubiquitin protein ligase E3C 
HERC3                 0.080   hect domain and RLD 3 
HECTD2                0.080   HECT domain containing 2 isoform a 
HERC4                 0.077   hect domain and RLD 4 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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