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Search of human proteins with 27436996
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27436996 potassium voltage-gated channel, subfamily G,
member 4 [Homo sapiens]
(519 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27436996 potassium voltage-gated channel, subfamily G, member... 1042 0.0
gi|27436988 potassium voltage-gated channel, subfamily G, member... 565 e-161
gi|6912444 potassium voltage-gated channel, subfamily G, member ... 504 e-143
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 347 1e-95
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 336 3e-92
gi|27436993 potassium voltage-gated channel, subfamily G, member... 333 3e-91
gi|19071574 potassium voltage-gated channel, subfamily G, member... 332 5e-91
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 290 2e-78
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 281 8e-76
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 281 1e-75
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 277 1e-74
gi|20070166 potassium voltage-gated channel, subfamily F, member... 268 1e-71
gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens] 265 8e-71
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 218 1e-56
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 214 2e-55
gi|163792201 Shaw-related voltage-gated potassium channel protei... 214 2e-55
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 213 3e-55
gi|119395748 potassium voltage-gated channel subfamily A member ... 210 2e-54
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 207 2e-53
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 207 2e-53
gi|21217561 Shaw-related voltage-gated potassium channel protein... 207 2e-53
gi|21217563 Shaw-related voltage-gated potassium channel protein... 207 2e-53
gi|24497458 Shaw-related voltage-gated potassium channel protein... 207 2e-53
gi|88758576 Shaw-related voltage-gated potassium channel protein... 206 4e-53
gi|24497462 Shaw-related voltage-gated potassium channel protein... 206 4e-53
gi|24497464 Shaw-related voltage-gated potassium channel protein... 206 4e-53
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 202 6e-52
gi|24497460 Shaw-related voltage-gated potassium channel protein... 202 8e-52
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 194 1e-49
gi|25952092 potassium voltage-gated channel, shaker-related subf... 194 1e-49
>gi|27436996 potassium voltage-gated channel, subfamily G, member 4
[Homo sapiens]
Length = 519
Score = 1042 bits (2695), Expect = 0.0
Identities = 519/519 (100%), Positives = 519/519 (100%)
Query: 1 MPMPSRDGGLHPRHHHYGSHSPWSQLLSSPMETPSIKGLYYRRVRKVGALDASPVDLKKE 60
MPMPSRDGGLHPRHHHYGSHSPWSQLLSSPMETPSIKGLYYRRVRKVGALDASPVDLKKE
Sbjct: 1 MPMPSRDGGLHPRHHHYGSHSPWSQLLSSPMETPSIKGLYYRRVRKVGALDASPVDLKKE 60
Query: 61 ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAF 120
ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAF
Sbjct: 61 ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAF 120
Query: 121 GVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHR 180
GVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHR
Sbjct: 121 GVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHR 180
Query: 181 EDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVSLCV 240
EDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVSLCV
Sbjct: 181 EDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVSLCV 240
Query: 241 STMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDI 300
STMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDI
Sbjct: 241 STMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDI 300
Query: 301 LAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTL 360
LAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTL
Sbjct: 301 LAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTL 360
Query: 361 GLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVG 420
GLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVG
Sbjct: 361 GLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVG 420
Query: 421 YGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHLQN 480
YGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHLQN
Sbjct: 421 YGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHLQN 480
Query: 481 TGPASECELLDPHVASEHELMNDVNDLILEGPALPIMHM 519
TGPASECELLDPHVASEHELMNDVNDLILEGPALPIMHM
Sbjct: 481 TGPASECELLDPHVASEHELMNDVNDLILEGPALPIMHM 519
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 565 bits (1456), Expect = e-161
Identities = 280/447 (62%), Positives = 343/447 (76%), Gaps = 7/447 (1%)
Query: 35 SIKGLYYRRVRKVGALD-----ASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLR 89
+IKG +YRR +++ D P D ++ I+INVGG +Y LPW+TLD FPL+RL +L+
Sbjct: 34 AIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLK 93
Query: 90 LCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAY 149
C ++++I+ +CDDYD EFFFDR+P AFG I++FL AGKL LL+EMCALSFQEEL Y
Sbjct: 94 ACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLY 153
Query: 150 WGIEEAHLERCCLRKLLRKLEELEELAKLHRED--VLRQQRETRRPASHSSRWGLCMNRL 207
WGI E HL+ CC R+ L+K+EE E+ + ED + + R++ PA R G CM RL
Sbjct: 154 WGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRL 213
Query: 208 REMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVET 267
R+MVE P SGLPGKVFACLS+LFV TAV+L VST+P LR EE+QG CS+ C+ +FIVE+
Sbjct: 214 RDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVES 273
Query: 268 ICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSS 327
+CV WFSLEF LR +QA K F + PL +ID++AI PYY++L V + +G+S
Sbjct: 274 VCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNS 333
Query: 328 YLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSP 387
YL+KVGLVLRVLRALRILYVMRLARHSLGLQTLGLT RRCTREFGLLLLFL VAI LF+P
Sbjct: 334 YLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAP 393
Query: 388 LVYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMA 447
L+YV E E EFTSIPA YWWA+I+MTTVGYGDMVPRS PGQ+VALSSILSGIL+MA
Sbjct: 394 LLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMA 453
Query: 448 FPATSIFHTFSHSYLELKKEQEQLQAR 474
FP TSIFHTFS SYLELK+EQE++ R
Sbjct: 454 FPVTSIFHTFSRSYLELKQEQERVMFR 480
>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
[Homo sapiens]
Length = 466
Score = 504 bits (1298), Expect = e-143
Identities = 252/412 (61%), Positives = 316/412 (76%), Gaps = 7/412 (1%)
Query: 59 KEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPS 118
+ ++INVGG R L W+ L R PL+RL +LR CR +++++++CDDYD EFFFDRSP
Sbjct: 17 RHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPC 76
Query: 119 AFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKL 178
AF IV+ L AGKL LL+ CAL+F++ELAYWGI+EA LERCCLR+L R+ EE E
Sbjct: 77 AFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARAG 136
Query: 179 HREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVSL 238
E Q R R RLR++V+NP SGL GK+FAC+S+ FVA TAV L
Sbjct: 137 PTER--GAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGL 194
Query: 239 CVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNII 298
C+STMPD+RAEE++GECS KC +F++ET+CVAWFS EF LR +QA+ KC F + PLNII
Sbjct: 195 CLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNII 254
Query: 299 DILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQ 358
DILA+ P+YVSL + P G+ LE+ GLVLR+LRALR+LYVMRLARHSLGL+
Sbjct: 255 DILALLPFYVSLLLGL-----AAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLR 309
Query: 359 TLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTT 418
+LGLT+RRC REFGLLLLFL VA+ LF+PLV++AE+E G +F+S+PASYWWA+ISMTT
Sbjct: 310 SLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTT 369
Query: 419 VGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQ 470
VGYGDMVPRS+PGQ+VALSSILSGIL+MAFP TSIFHTFS SY ELK++Q++
Sbjct: 370 VGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQR 421
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 347 bits (891), Expect = 1e-95
Identities = 187/473 (39%), Positives = 292/473 (61%), Gaps = 33/473 (6%)
Query: 38 GLYYRRVRKVGALDASPVDL------KKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLC 91
GL + R +L PVD+ + + INVGG + + W TLDR P +RL KLR C
Sbjct: 8 GLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDC 67
Query: 92 RSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWG 151
++E ++++CDDY+ + E+FFDR P AF I++F GKL +++EMCALSF +EL YWG
Sbjct: 68 NTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWG 127
Query: 152 IEEAHLERCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPASHSSRWGLC----MNRL 207
I+E +LE CC + +K E++ E LR++ ET R C +L
Sbjct: 128 IDEIYLESCCQARYHQKKEQMNE--------ELRREAETMREREGEEFDNTCCPDKRKKL 179
Query: 208 REMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVET 267
+++E P S + K+ A +SILF+ + ++L ++T+P+L+ ++ G+ + + VE
Sbjct: 180 WDLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEFGQLNDN-RQLAHVEA 238
Query: 268 ICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSS 327
+C+AWF++E+ LRF+ + +K +FF+GPLN+ID+LAI PYYV++ ++E S S
Sbjct: 239 VCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTE---------SNKS 289
Query: 328 YL--EKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLF 385
L + V V+++ R +RIL +++LARHS GLQ+LG T+RR E GLL+LFLA+ I +F
Sbjct: 290 VLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIF 349
Query: 386 SPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILI 445
S LV+ AEK+ +FTSIPAS+WWA I+MTTVGYGD+ P+++ G++V ++G+L+
Sbjct: 350 SSLVFFAEKDED-ATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLV 408
Query: 446 MAFPATSIFHTFSHSYLELKKEQEQLQAR--LRHLQNTGPASECELLDPHVAS 496
+A P I + FS Y E K++++ ++ R L + G L D S
Sbjct: 409 IALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARS 461
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 336 bits (862), Expect = 3e-92
Identities = 172/438 (39%), Positives = 280/438 (63%), Gaps = 23/438 (5%)
Query: 45 RKVGALDASPVDL------KKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIV 98
R +L P+++ + + +NVGG + + W TLDR P +RL KLR C +++ ++
Sbjct: 11 RSTSSLPPEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLL 70
Query: 99 QLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLE 158
++CDDY D E+FFDR P AF I++F G+L +++EMCALSF +EL YWGI+E +LE
Sbjct: 71 EVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLE 130
Query: 159 RCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGL 218
CC + +K E++ E K E + ++ E + + +L +++E P S +
Sbjct: 131 SCCQARYHQKKEQMNEELKREAETLREREGEEFDNTCCAEK----RKKLWDLLEKPNSSV 186
Query: 219 PGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFC 278
K+ A +SI+F+ + ++L ++T+P+L++ ++ G+ S + VE +C+AWF++E+
Sbjct: 187 AAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQ-STDNPQLAHVEAVCIAWFTMEYL 245
Query: 279 LRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYL--EKVGLVL 336
LRF+ + K +FF+GPLN ID+LAI PYYV++ ++E S S L + V V+
Sbjct: 246 LRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIFLTE---------SNKSVLQFQNVRRVV 296
Query: 337 RVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKES 396
++ R +RIL +++LARHS GLQ+LG T+RR E GLL+LFLA+ I +FS LV+ AEK+
Sbjct: 297 QIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDE 356
Query: 397 GRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHT 456
+F SIPAS+WWA I+MTTVGYGD+ P+++ G++V ++G+L++A P I +
Sbjct: 357 DDT-KFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNN 415
Query: 457 FSHSYLELKKEQEQLQAR 474
FS Y E K++++ ++ R
Sbjct: 416 FSEFYKEQKRQEKAIKRR 433
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 333 bits (853), Expect = 3e-91
Identities = 183/416 (43%), Positives = 261/416 (62%), Gaps = 28/416 (6%)
Query: 61 ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAF 120
+++NVGG RY L L FPL R+S+L CRS +++++CDDYD + E+FFDR AF
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 121 GVIVSFLAA-GKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLH 179
G I+ ++ GKL MC LSF E+ YWG+E AHLE CC R+L ++ +
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 180 REDVLRQQRETRRP----ASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTA 235
VL R+ RP A+ S RW + R+R E P S L ++ A +S++FV +
Sbjct: 131 EPGVLG--RDEARPGGAEAAPSRRW---LERMRRTFEEPTSSLAAQILASVSVVFVIVSM 185
Query: 236 VSLCVSTMPDLR-AEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGP 294
V LC ST+PD R A D + I+E IC+ WF+ E +RF+ +++KC+F + P
Sbjct: 186 VVLCASTLPDWRNAAADNRSLDDRSR---IIEAICIGWFTAECIVRFIVSKNKCEFVKRP 242
Query: 295 LNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHS 354
LNIID+LAI+PYY+S+ ++ E+ S L++ G+ LRVLR +RI +V++LARH
Sbjct: 243 LNIIDLLAITPYYISVLMTVFTGEN-------SQLQRAGVTLRVLRMMRIFWVIKLARHF 295
Query: 355 LGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLE-----FTSIPASY 409
+GLQTLGLT++RC RE +LL+F+ VA+ +FS L + E G LE FTSIPA+
Sbjct: 296 IGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEH--GLDLETSNKDFTSIPAAC 353
Query: 410 WWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELK 465
WW IISMTTVGYGDM P +VPG+++ ++SGI+++A P T I+H+F Y ELK
Sbjct: 354 WWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 409
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 332 bits (851), Expect = 5e-91
Identities = 184/424 (43%), Positives = 262/424 (61%), Gaps = 33/424 (7%)
Query: 61 ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAF 120
+++NVGG RY L L FPL R+S+L CRS +++++CDDYD + E+FFDR AF
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 121 GVIVSFLAA-GKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLH 179
G I+ ++ GKL MC LSF E+ YWG+E AHLE CC R+L ++ +
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 180 REDVLRQQRETRRP----ASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTA 235
VL R+ RP A+ S RW + R+R E P S L ++ A +S++FV +
Sbjct: 131 EPGVLG--RDEARPGGAEAAPSRRW---LERMRRTFEEPTSSLAAQILASVSVVFVIVSM 185
Query: 236 VSLCVSTMPDLR-AEEDQGECSRKCYYIF--------IVETICVAWFSLEFCLRFVQAQD 286
V LC ST+PD R A D + Y I+E IC+ WF+ E +RF+ +++
Sbjct: 186 VVLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIVRFIVSKN 245
Query: 287 KCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILY 346
KC+F + PLNIID+LAI+PYY+S+ ++ E+ S L++ G+ LRVLR +RI +
Sbjct: 246 KCEFVKRPLNIIDLLAITPYYISVLMTVFTGEN-------SQLQRAGVTLRVLRMMRIFW 298
Query: 347 VMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLE----- 401
V++LARH +GLQTLGLT++RC RE +LL+F+ VA+ +FS L + E G LE
Sbjct: 299 VIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEH--GLDLETSNKD 356
Query: 402 FTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSY 461
FTSIPA+ WW IISMTTVGYGDM P +VPG+++ ++SGI+++A P T I+H+F Y
Sbjct: 357 FTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCY 416
Query: 462 LELK 465
ELK
Sbjct: 417 HELK 420
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 290 bits (743), Expect = 2e-78
Identities = 167/430 (38%), Positives = 257/430 (59%), Gaps = 32/430 (7%)
Query: 60 EILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSA 119
EI INVGG + L TL RFP +RL +L LC S E I++LCDDYD+ +EF+FDR+P
Sbjct: 18 EIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPEL 77
Query: 120 FGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCL-----RKLLRKLEELEE 174
F ++ F GKL ++ E+C SF +E+ YWGI E ++ CC RK+ + E+ +E
Sbjct: 78 FPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDE 137
Query: 175 LAKLHREDVLRQQRETRRPASHSSRW-----GLCMNRLREMVENPQSGLPGKVFACLSIL 229
+ +E E + +S++ G +L ++NP + +VF+ LSIL
Sbjct: 138 QSD--QESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSIL 195
Query: 230 FVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQ 289
V + +++C++++PD + + QG + IVE +AWF+ E RF A D +
Sbjct: 196 VVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFE-IVEHFGIAWFTFELVARFAVAPDFLK 254
Query: 290 FFQGPLNIIDILAISPYYVSLAVS---EEPPEDGERPSGSSYLEKVGLVLRVLRALRILY 346
FF+ LN+ID+++I P+Y++L V+ E P L +G V +VLR +RI
Sbjct: 255 FFKNALNLIDLMSIVPFYITLVVNLVVESTPT----------LANLGRVAQVLRLMRIFR 304
Query: 347 VMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIP 406
+++LARHS GL++LG T++ +E GLLLL+L+V I++FS + Y EKE L +IP
Sbjct: 305 ILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEENEGL--ATIP 362
Query: 407 ASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKK 466
A +WWA +SMTTVGYGD+VP + G++ A + IL+GIL++ P T IF+ FSH Y +
Sbjct: 363 ACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFY----R 418
Query: 467 EQEQLQARLR 476
Q+QL++ +R
Sbjct: 419 RQKQLESAMR 428
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 281 bits (720), Expect = 8e-76
Identities = 157/417 (37%), Positives = 243/417 (58%), Gaps = 32/417 (7%)
Query: 63 INVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGV 122
+NVGG + + STL RFP +RL KL C S E I++LCDDY +E++FDR+PS F
Sbjct: 19 LNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRY 78
Query: 123 IVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHRED 182
+++F GKL +++E+C SF +E+ YWGI E ++ CC + + EE H +D
Sbjct: 79 VLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEE------NHEKD 132
Query: 183 VLRQQRETRRPASHSS--------------RWGLCMNRLREMVENPQSGLPGKVFACLSI 228
++ + +S R+G ++ +ENP L K+ A S+
Sbjct: 133 WDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSL 192
Query: 229 LFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKC 288
V + V++CV +M + + E+ + + + VE C+AWF+ E +R A +
Sbjct: 193 SVVLASIVAMCVHSMSEFQNEDGEVDDP----VLEGVEIACIAWFTGELAVRLAAAPCQK 248
Query: 289 QFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVM 348
+F++ PLNIID ++I P+Y +LAV + E S +E +G V+++LR +RI ++
Sbjct: 249 KFWKNPLNIIDFVSIIPFYATLAVDTKEEE-------SEDIENMGKVVQILRLMRIFRIL 301
Query: 349 RLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPAS 408
+LARHS+GL++LG T+R E GLLLLFL+V I++FS L+Y EK+ TSIP
Sbjct: 302 KLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDD-HTSSLTSIPIC 360
Query: 409 YWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELK 465
+WWA ISMTTVGYGD P ++ G+++A + I+ GIL++A P T IF+ FS Y + K
Sbjct: 361 WWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQK 417
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 281 bits (718), Expect = 1e-75
Identities = 167/436 (38%), Positives = 250/436 (57%), Gaps = 34/436 (7%)
Query: 63 INVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGV 122
+NVGG R L L RFP +RL +L+ S E+ +LCDDYDE ++EF+FDR P F
Sbjct: 54 VNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPGFFLS 113
Query: 123 IVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCC-LRKLLRKL-------EELEE 174
++ F G L +L E+C +F +E YWG+ E L CC R L R+L E+ +
Sbjct: 114 LLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLTQPHAWDEDSDT 173
Query: 175 LAKLH--REDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVA 232
+ + +++ QRE R ++R G RL +ENP LP K+F+C+SI V
Sbjct: 174 PSSVDPCPDEISDVQRELARYG--AARCGRLRRRLWLTMENPGYSLPSKLFSCVSISVVL 231
Query: 233 TTAVSLCVSTMPDLRAEEDQG-----------ECSRKCYYIFIVETICVAWFSLEFCLRF 281
+ ++C+ ++P+ +A E E R + +E C+AWFS E R
Sbjct: 232 ASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSFEVSSRL 291
Query: 282 VQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRA 341
+ A FF PLN+IDI+++ P+Y++L + G + G +G V++V R
Sbjct: 292 LLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGKEFG-----HLGKVVQVFRL 346
Query: 342 LRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLE 401
+RI V++LARHS GL++LG T++ RE G+LLL+LAV +++FS + Y AEKE +
Sbjct: 347 MRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKEED--VG 404
Query: 402 FTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSY 461
F +IPA +WW +SMTTVGYGD+VP +V G++ A IL GIL++A P T IF+ FSH Y
Sbjct: 405 FNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFY 464
Query: 462 LELKKEQEQLQARLRH 477
+ Q+ L+A +R+
Sbjct: 465 ----RRQKALEAAVRN 476
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 277 bits (709), Expect = 1e-74
Identities = 169/469 (36%), Positives = 265/469 (56%), Gaps = 48/469 (10%)
Query: 26 LLSSPMETPSIKGLYYRRVRKVGALDASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRL 85
LL SP+++ S+ L G + P+ L +NVGG R++L L FP +RL
Sbjct: 8 LLDSPLDSGSLTSLDSSVFCSEG--EGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRL 65
Query: 86 SKLRLC-RSYEEI---------VQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLL 135
KL + SY ++LCDD + E+FFDRS AF ++ + G+L ++
Sbjct: 66 GKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVM 125
Query: 136 QEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPAS 195
+++CALSF +E+ YWGI+E ++ CC + R+ +EL E ++ + +E++ +
Sbjct: 126 EQLCALSFLQEIQYWGIDELSIDSCCRDRYFRR-KELSETLDFKKD---TEDQESQHESE 181
Query: 196 HSSRWGLC---MNRLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMP----DLRA 248
G C +L ++E P S ++F +SI+FV + +++ + + DL+
Sbjct: 182 QDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQL 241
Query: 249 EEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYV 308
E I+E +C++WF+ EF LRF+ +D+C+F + NIID+LAI P+Y+
Sbjct: 242 LE-------------ILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYI 288
Query: 309 SLAVSEEPPEDGERPSGS---SYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVR 365
+L V E SGS LE VG +++VLR LR L +++L RHS GL++LG+T+
Sbjct: 289 TLLV--------ESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTIT 340
Query: 366 RCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMV 425
+C E GLLLLFL+V I++FS + Y AE +S FTS+P ++WWA SMTTVGYGD+
Sbjct: 341 QCYEEVGLLLLFLSVGISIFSTVEYFAE-QSIPDTTFTSVPCAWWWATTSMTTVGYGDIR 399
Query: 426 PRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQAR 474
P + G++VA ILSGIL++A P I FS Y LK ++ ++ R
Sbjct: 400 PDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQR 448
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 268 bits (684), Expect = 1e-71
Identities = 155/423 (36%), Positives = 239/423 (56%), Gaps = 26/423 (6%)
Query: 60 EILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRS--YEEIVQLCDDYDEDSQEFFFDRSP 117
EI++NVGG R +L L ++P +RL++L C + Y+ I LCDDYD +EF+FDR P
Sbjct: 24 EIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDP 83
Query: 118 SAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAK 177
AF ++ G++ + + +C + F+ E+ +W ++ L+ CC L K EELEE+A+
Sbjct: 84 DAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIAR 143
Query: 178 ---LHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATT 234
L +D+ E RW C + + +E P+S P +V A LS L + +
Sbjct: 144 RVQLILDDLGVDAAE--------GRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVS 195
Query: 235 AVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGP 294
+V +C+ T+P+L+ + +G + + VET C+ WF+LE+ LR + +K F
Sbjct: 196 SVVMCMGTIPELQVLDAEGN-RVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSF 254
Query: 295 LNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHS 354
+NI+D+LAI P+YVSL ++ E L V ++ LR +RI + +LARHS
Sbjct: 255 MNIVDVLAILPFYVSLTLTHLGARMME-------LTNVQQAVQALRIMRIARIFKLARHS 307
Query: 355 LGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAII 414
GLQTL ++R +E GLLL++LAV I +FS L Y E+ L F SIP S+WWAII
Sbjct: 308 SGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETL-FKSIPQSFWWAII 366
Query: 415 SMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQAR 474
+MTTVGYGD+ P++ G++ A S L G++ +A P I + F Y +Q L+
Sbjct: 367 TMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYY----NKQRVLETA 422
Query: 475 LRH 477
+H
Sbjct: 423 AKH 425
>gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]
Length = 545
Score = 265 bits (677), Expect = 8e-71
Identities = 149/416 (35%), Positives = 227/416 (54%), Gaps = 3/416 (0%)
Query: 52 ASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEF 111
+ P L + +NVGG Y L + L FP +RL +L S + LCDDY+E + E+
Sbjct: 90 SDPPALLSTLNVNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEY 149
Query: 112 FFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEE 171
FFDR P+ F ++ +F +G L++L +C F EEL YWG+ + RCC + +E
Sbjct: 150 FFDRDPAVFQLVYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDE 209
Query: 172 LEELAKLHREDVLRQQRETRRPASHSSR-WGLCMNRLREMVENPQSGLPGKVFACLSILF 230
L E K+ E + Q E R +G RL ++E P S + K S F
Sbjct: 210 LSERLKIQHELRAQAQVEEAEELFRDMRFYGPQRRRLWNLMEKPFSSVAAKAIGVASSTF 269
Query: 231 VATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFI-VETICVAWFSLEFCLRFVQAQDKCQ 289
V + V+L ++T+ +++ QGE I VE +C+ +F+LE+ LR D +
Sbjct: 270 VLVSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRR 329
Query: 290 FFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMR 349
F + LN++D++AI P Y+ L + E +R + KVG VLRV+R +RI +++
Sbjct: 330 FARSALNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQVLRVMRLMRIFRILK 389
Query: 350 LARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASY 409
LARHS GL+ G T+R+C ++ G LLLF+A+ I FS VY E + FT+IP S+
Sbjct: 390 LARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHDVPST-NFTTIPHSW 448
Query: 410 WWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELK 465
WWA +S++TVGYGDM P + G+ A I GI++ P + +++ FS Y +LK
Sbjct: 449 WWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLK 504
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 218 bits (554), Expect = 1e-56
Identities = 140/427 (32%), Positives = 220/427 (51%), Gaps = 40/427 (9%)
Query: 61 ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAF 120
+++NV GRR+ +TLDR+P + L S +E YD DS E+FFDR P F
Sbjct: 42 LVVNVSGRRFETWKNTLDRYPDTLLGS-----SEKEFF-----YDADSGEYFFDRDPDMF 91
Query: 121 GVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLL-RKLEELEELAKLH 179
+++F G+L ++ C +F EELA++G+ + CCL + RK E E LA+
Sbjct: 92 RHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAE-- 149
Query: 180 REDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVSLC 239
E+ + PA S R RL ENP + VF ++ F+A + ++
Sbjct: 150 DEEAEQAGDGPALPAGSSLR-----QRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANV 204
Query: 240 VSTMP----DLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPL 295
V T+P R+ +Q R F ++T CV F+ E+ LR A +C+F + +
Sbjct: 205 VETIPCRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVM 264
Query: 296 NIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSL 355
++ID++AI PYY+ L V + G LR R+ + + +RHS
Sbjct: 265 SLIDVVAILPYYIGLLVPKNDDVSG--------------AFVTLRVFRVFRIFKFSRHSQ 310
Query: 356 GLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIIS 415
GL+ LG T++ C E G LL L +AI +F+ +++ AEK + + FTSIPA++W+ I++
Sbjct: 311 GLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKT-NFTSIPAAFWYTIVT 369
Query: 416 MTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFS---HSYLELKKEQEQLQ 472
MTT+GYGDMVP ++ G++ LSG+L++A P I FS H K + Q +
Sbjct: 370 MTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQK 429
Query: 473 ARLRHLQ 479
RL ++
Sbjct: 430 VRLARIR 436
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 214 bits (545), Expect = 2e-55
Identities = 145/507 (28%), Positives = 239/507 (47%), Gaps = 66/507 (13%)
Query: 56 DLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDR 115
D + I+INVGG R+ STL P +RL+ L ++ DYD + EFFFDR
Sbjct: 5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHF-----DYDPRADEFFFDR 59
Query: 116 SPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEEL 175
P F I+++ GKL ++C ++EELA+WGI+E +E CC + + E L
Sbjct: 60 HPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEAL 119
Query: 176 AKL---------------------HREDVLRQQRETRRPASHSSR----WGLCMNRLREM 210
ED L + S R W R+ +
Sbjct: 120 DSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWAL 179
Query: 211 VENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGEC------SRKCYY--- 261
E+P S + A S+ F+ + + C+ T ++ E ++ YY
Sbjct: 180 FEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREA 239
Query: 262 -----IFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEP 316
+ +E +CV WF+ EF +R + +K +F + LNIID +AI P+Y+ + +S
Sbjct: 240 ETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLS 299
Query: 317 PEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLL 376
+ + G LRV+R +RIL + +L RH +GL+ LG T+R T EF LL++
Sbjct: 300 SKAAKDVLG---------FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLII 350
Query: 377 FLAVAITLFSPLVYVAEK--------ESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRS 428
FLA+ + +F+ ++Y AE+ + F +IP +WWA+++MTT+GYGDM P++
Sbjct: 351 FLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQT 410
Query: 429 VPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHL---QNTGPAS 485
G +V L+G+L +A P I + F Y +Q+ + + +H+ G +
Sbjct: 411 WSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPN 470
Query: 486 ECELL--DPHVASEHELMNDVNDLILE 510
C+ + PH +++ + + ILE
Sbjct: 471 YCKSVVNSPHHSTQSDTCPLAQEEILE 497
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 214 bits (545), Expect = 2e-55
Identities = 145/507 (28%), Positives = 239/507 (47%), Gaps = 66/507 (13%)
Query: 56 DLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDR 115
D + I+INVGG R+ STL P +RL+ L ++ DYD + EFFFDR
Sbjct: 5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHF-----DYDPRADEFFFDR 59
Query: 116 SPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEEL 175
P F I+++ GKL ++C ++EELA+WGI+E +E CC + + E L
Sbjct: 60 HPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEAL 119
Query: 176 AKL---------------------HREDVLRQQRETRRPASHSSR----WGLCMNRLREM 210
ED L + S R W R+ +
Sbjct: 120 DSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWAL 179
Query: 211 VENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGEC------SRKCYY--- 261
E+P S + A S+ F+ + + C+ T ++ E ++ YY
Sbjct: 180 FEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREA 239
Query: 262 -----IFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEP 316
+ +E +CV WF+ EF +R + +K +F + LNIID +AI P+Y+ + +S
Sbjct: 240 ETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLS 299
Query: 317 PEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLL 376
+ + G LRV+R +RIL + +L RH +GL+ LG T+R T EF LL++
Sbjct: 300 SKAAKDVLG---------FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLII 350
Query: 377 FLAVAITLFSPLVYVAEK--------ESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRS 428
FLA+ + +F+ ++Y AE+ + F +IP +WWA+++MTT+GYGDM P++
Sbjct: 351 FLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQT 410
Query: 429 VPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHL---QNTGPAS 485
G +V L+G+L +A P I + F Y +Q+ + + +H+ G +
Sbjct: 411 WSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPN 470
Query: 486 ECELL--DPHVASEHELMNDVNDLILE 510
C+ + PH +++ + + ILE
Sbjct: 471 YCKSVVNSPHHSTQSDTCPLAQEEILE 497
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 213 bits (543), Expect = 3e-55
Identities = 137/434 (31%), Positives = 218/434 (50%), Gaps = 58/434 (13%)
Query: 59 KEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPS 118
+ ++IN+ G R+ TL +FP + L + Y +D E+FFDR+
Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRY---------FDPLRNEYFFDRNRP 83
Query: 119 AFGVIVSFLAAGKLVLLQEMCALS-FQEELAYWGIEEAHLERCCLRKLLRKLEELEELAK 177
+F I+ + +G + L F EE+ ++ + E +E
Sbjct: 84 SFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAME------------------- 124
Query: 178 LHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVS 237
+ RED +E RP + ++ + E P+S P ++ A +S++ + + VS
Sbjct: 125 MFREDE-GYIKEEERPLPENE----FQRQVWLLFEYPESSGPARIIAIVSVMVILISIVS 179
Query: 238 LCVSTMPDLRAEEDQGECSRKCYY------------------IFIVETICVAWFSLEFCL 279
C+ T+P R E + S ++ FIVET+C+ WFS EF +
Sbjct: 180 FCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLV 239
Query: 280 RFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVS-EEPPEDGERPSGSSYLEKVGLVLRV 338
RF K FF +NIIDI+AI PY+++L E PED ++ + L +LRV
Sbjct: 240 RFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLA----ILRV 295
Query: 339 LRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGR 398
+R +R+ + +L+RHS GLQ LG T++ RE GLL+ FL + + LFS VY AE + R
Sbjct: 296 IRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADE-R 354
Query: 399 VLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFS 458
+F SIP ++WWA++SMTTVGYGDMVP ++ G++V ++G+L +A P I F+
Sbjct: 355 ESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFN 414
Query: 459 HSYLELKKEQEQLQ 472
+ Y + +EQ Q
Sbjct: 415 YFYHRETEGEEQAQ 428
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 210 bits (535), Expect = 2e-54
Identities = 136/445 (30%), Positives = 224/445 (50%), Gaps = 54/445 (12%)
Query: 59 KEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPS 118
+ ++IN+ G R+ TL +FP + L + Y +D E+FFDR+
Sbjct: 37 ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRY---------FDPLRNEYFFDRNRP 87
Query: 119 AFGVIVSFLAAGKLVLLQEMCALS-FQEELAYWGIEEAHLERCCLRKLLRKLEELEELAK 177
+F I+ + +G + L F EE+ ++ + E E + K
Sbjct: 88 SFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGE------------------EAMEK 129
Query: 178 LHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVS 237
++ ++ E P R ++ + E P+S P +V A +S++ + + V
Sbjct: 130 FREDEGFIKEEERPLPEKEYQR------QVWLLFEYPESSGPARVIAIVSVMVILISIVI 183
Query: 238 LCVSTMPDLRAEED-QGECSR----KCYY--------IFIVETICVAWFSLEFCLRFVQA 284
C+ T+P+L+ ++D G R Y FIVET+C+ WFS E +RF
Sbjct: 184 FCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFAC 243
Query: 285 QDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRI 344
K FF+ +N IDI+AI PY+++L E ++ ++ L +LRV+R +R+
Sbjct: 244 PSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLA----ILRVIRLVRV 299
Query: 345 LYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTS 404
+ +L+RHS GLQ LG T++ RE GLL+ FL + + LFS VY AE E F+S
Sbjct: 300 FRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES-HFSS 358
Query: 405 IPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLEL 464
IP ++WWA++SMTTVGYGDM P ++ G++V ++G+L +A P I F++ Y
Sbjct: 359 IPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRE 418
Query: 465 KKEQEQLQARLRHLQNTGPASECEL 489
+ +E QA+L H+ + AS+ +L
Sbjct: 419 TEGEE--QAQLLHVSSPNLASDSDL 441
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 207 bits (527), Expect = 2e-53
Identities = 135/437 (30%), Positives = 220/437 (50%), Gaps = 45/437 (10%)
Query: 53 SPVDLKKE----ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDS 108
+P D K I++NV GRR+ +TL+R+P + L +E ++ED+
Sbjct: 30 APADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTE-----KEFF-----FNEDT 79
Query: 109 QEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLL-R 167
+E+FFDR P F +++F GKL + C ++ +ELA++GI + CC + R
Sbjct: 80 KEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDR 139
Query: 168 KLEELEELAKLHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLS 227
K E E L + D Q + + W ENP + VF ++
Sbjct: 140 KRENAERL--MDDNDSENNQESMPSLSFRQTMW--------RAFENPHTSTLALVFYYVT 189
Query: 228 ILFVATTAVSLCVSTMP--DLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQ 285
F+A + ++ V T+P + ++ R F ++T CV F++E+ LR A
Sbjct: 190 GFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAP 249
Query: 286 DKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRIL 345
+ +F + ++IID++AI PYY+ L ++ E V LR R+
Sbjct: 250 SRYRFIRSVMSIIDVVAIMPYYIGLVMTNN--------------EDVSGAFVTLRVFRVF 295
Query: 346 YVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSI 405
+ + +RHS GL+ LG T++ C E G LL L +AI +F+ +++ AEK S +FTSI
Sbjct: 296 RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSS-ASKFTSI 354
Query: 406 PASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFS---HSYL 462
PAS+W+ I++MTT+GYGDMVP+++ G++ LSG+L++A P I FS H
Sbjct: 355 PASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ 414
Query: 463 ELKKEQEQLQARLRHLQ 479
K + Q +ARL ++
Sbjct: 415 RADKRRAQKKARLARIR 431
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 207 bits (527), Expect = 2e-53
Identities = 135/437 (30%), Positives = 220/437 (50%), Gaps = 45/437 (10%)
Query: 53 SPVDLKKE----ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDS 108
+P D K I++NV GRR+ +TL+R+P + L +E ++ED+
Sbjct: 30 APADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTE-----KEFF-----FNEDT 79
Query: 109 QEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLL-R 167
+E+FFDR P F +++F GKL + C ++ +ELA++GI + CC + R
Sbjct: 80 KEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDR 139
Query: 168 KLEELEELAKLHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLS 227
K E E L + D Q + + W ENP + VF ++
Sbjct: 140 KRENAERL--MDDNDSENNQESMPSLSFRQTMW--------RAFENPHTSTLALVFYYVT 189
Query: 228 ILFVATTAVSLCVSTMP--DLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQ 285
F+A + ++ V T+P + ++ R F ++T CV F++E+ LR A
Sbjct: 190 GFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAP 249
Query: 286 DKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRIL 345
+ +F + ++IID++AI PYY+ L ++ E V LR R+
Sbjct: 250 SRYRFIRSVMSIIDVVAIMPYYIGLVMTNN--------------EDVSGAFVTLRVFRVF 295
Query: 346 YVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSI 405
+ + +RHS GL+ LG T++ C E G LL L +AI +F+ +++ AEK S +FTSI
Sbjct: 296 RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSS-ASKFTSI 354
Query: 406 PASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFS---HSYL 462
PAS+W+ I++MTT+GYGDMVP+++ G++ LSG+L++A P I FS H
Sbjct: 355 PASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ 414
Query: 463 ELKKEQEQLQARLRHLQ 479
K + Q +ARL ++
Sbjct: 415 RADKRRAQKKARLARIR 431
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 207 bits (527), Expect = 2e-53
Identities = 126/420 (30%), Positives = 207/420 (49%), Gaps = 46/420 (10%)
Query: 103 DYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCL 162
D+ +EFFFDR P F ++++ GKL ++C F+EELA+WGI+E +E CC
Sbjct: 94 DHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCW 153
Query: 163 RKLLRKLEELEELAKLHREDVLR------QQRETRR-----------PASHSSRWGLCMN 205
+ + E L D++ + +R P S RW
Sbjct: 154 MTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQP 213
Query: 206 RLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGE-----CSRKCY 260
R+ + E+P S + A S+ F+ + + C+ T +++ E S
Sbjct: 214 RMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQ 273
Query: 261 Y-------IFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVS 313
Y + VE +CV WF+ EF +R V + +K +F + LNIID +AI P+Y+ + +S
Sbjct: 274 YEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLS 333
Query: 314 EEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGL 373
+ + G LRV+R +RIL + +L RH +GL+ LG T+R T EF L
Sbjct: 334 GLSSKAAKDVLG---------FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLL 384
Query: 374 LLLFLAVAITLFSPLVYVAEK--------ESGRVLEFTSIPASYWWAIISMTTVGYGDMV 425
L++FLA+ + +F+ ++Y AE+ + +F +IP +WWA+++MTT+GYGDM
Sbjct: 385 LIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMY 444
Query: 426 PRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHLQNTGPAS 485
P++ G +V L+G+L +A P I + F Y +Q+ + R +H+ AS
Sbjct: 445 PQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQAS 504
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 207 bits (527), Expect = 2e-53
Identities = 126/420 (30%), Positives = 207/420 (49%), Gaps = 46/420 (10%)
Query: 103 DYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCL 162
D+ +EFFFDR P F ++++ GKL ++C F+EELA+WGI+E +E CC
Sbjct: 94 DHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCW 153
Query: 163 RKLLRKLEELEELAKLHREDVLR------QQRETRR-----------PASHSSRWGLCMN 205
+ + E L D++ + +R P S RW
Sbjct: 154 MTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQP 213
Query: 206 RLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGE-----CSRKCY 260
R+ + E+P S + A S+ F+ + + C+ T +++ E S
Sbjct: 214 RMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQ 273
Query: 261 Y-------IFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVS 313
Y + VE +CV WF+ EF +R V + +K +F + LNIID +AI P+Y+ + +S
Sbjct: 274 YEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLS 333
Query: 314 EEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGL 373
+ + G LRV+R +RIL + +L RH +GL+ LG T+R T EF L
Sbjct: 334 GLSSKAAKDVLG---------FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLL 384
Query: 374 LLLFLAVAITLFSPLVYVAEK--------ESGRVLEFTSIPASYWWAIISMTTVGYGDMV 425
L++FLA+ + +F+ ++Y AE+ + +F +IP +WWA+++MTT+GYGDM
Sbjct: 385 LIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMY 444
Query: 426 PRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHLQNTGPAS 485
P++ G +V L+G+L +A P I + F Y +Q+ + R +H+ AS
Sbjct: 445 PQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQAS 504
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 207 bits (527), Expect = 2e-53
Identities = 126/420 (30%), Positives = 207/420 (49%), Gaps = 46/420 (10%)
Query: 103 DYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCL 162
D+ +EFFFDR P F ++++ GKL ++C F+EELA+WGI+E +E CC
Sbjct: 94 DHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCW 153
Query: 163 RKLLRKLEELEELAKLHREDVLR------QQRETRR-----------PASHSSRWGLCMN 205
+ + E L D++ + +R P S RW
Sbjct: 154 MTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQP 213
Query: 206 RLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGE-----CSRKCY 260
R+ + E+P S + A S+ F+ + + C+ T +++ E S
Sbjct: 214 RMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQ 273
Query: 261 Y-------IFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVS 313
Y + VE +CV WF+ EF +R V + +K +F + LNIID +AI P+Y+ + +S
Sbjct: 274 YEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLS 333
Query: 314 EEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGL 373
+ + G LRV+R +RIL + +L RH +GL+ LG T+R T EF L
Sbjct: 334 GLSSKAAKDVLG---------FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLL 384
Query: 374 LLLFLAVAITLFSPLVYVAEK--------ESGRVLEFTSIPASYWWAIISMTTVGYGDMV 425
L++FLA+ + +F+ ++Y AE+ + +F +IP +WWA+++MTT+GYGDM
Sbjct: 385 LIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMY 444
Query: 426 PRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHLQNTGPAS 485
P++ G +V L+G+L +A P I + F Y +Q+ + R +H+ AS
Sbjct: 445 PQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQAS 504
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 206 bits (524), Expect = 4e-53
Identities = 150/495 (30%), Positives = 231/495 (46%), Gaps = 68/495 (13%)
Query: 43 RVRKVGALDASPVDLKKE---------ILINVGGRRYLLPWSTLDRFPLSRLSKLR---- 89
R RK G S LK+E I+INVGG R+ STL P +RL+ L
Sbjct: 11 RGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDG 70
Query: 90 --LCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEEL 147
+ V EFFFDR P F ++++ GKL ++C F+EEL
Sbjct: 71 GGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEEL 130
Query: 148 AYWGIEEAHLERCCLR--KLLRKLEEL-----------------EELAKLHREDVLRQQR 188
+WGI+E +E CC + R EE +E RE L++
Sbjct: 131 TFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLG 190
Query: 189 ETRRPASHSSRWGLCMN---RLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPD 245
A H + G C R+ + E+P S +V A S+ F+ + + C+ T
Sbjct: 191 PHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEA 250
Query: 246 LRAEEDQGECSRKCYYIFI--------------VETICVAWFSLEFCLRFVQAQDKCQFF 291
+ + E R + +E +CV WF+LEF +R V D F
Sbjct: 251 FNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFV 310
Query: 292 QGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLA 351
+ LNIID +AI P+Y+ + +S S + + +G LRV+R +RIL + +L
Sbjct: 311 KNLLNIIDFVAILPFYLEVGLSGL--------SSKAARDVLGF-LRVVRFVRILRIFKLT 361
Query: 352 RHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRV--------LEFT 403
RH +GL+ LG T+R T EF LL++FLA+ + +F+ ++Y AE+ R +F
Sbjct: 362 RHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFK 421
Query: 404 SIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLE 463
+IP +WWA+++MTT+GYGDM P++ G +V L+G+L +A P I + F Y
Sbjct: 422 NIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSL 481
Query: 464 LKKEQEQLQARLRHL 478
+Q+ + R +H+
Sbjct: 482 AMAKQKLPKKRKKHV 496
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 206 bits (524), Expect = 4e-53
Identities = 150/495 (30%), Positives = 231/495 (46%), Gaps = 68/495 (13%)
Query: 43 RVRKVGALDASPVDLKKE---------ILINVGGRRYLLPWSTLDRFPLSRLSKLR---- 89
R RK G S LK+E I+INVGG R+ STL P +RL+ L
Sbjct: 11 RGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDG 70
Query: 90 --LCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEEL 147
+ V EFFFDR P F ++++ GKL ++C F+EEL
Sbjct: 71 GGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEEL 130
Query: 148 AYWGIEEAHLERCCLR--KLLRKLEEL-----------------EELAKLHREDVLRQQR 188
+WGI+E +E CC + R EE +E RE L++
Sbjct: 131 TFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLG 190
Query: 189 ETRRPASHSSRWGLCMN---RLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPD 245
A H + G C R+ + E+P S +V A S+ F+ + + C+ T
Sbjct: 191 PHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEA 250
Query: 246 LRAEEDQGECSRKCYYIFI--------------VETICVAWFSLEFCLRFVQAQDKCQFF 291
+ + E R + +E +CV WF+LEF +R V D F
Sbjct: 251 FNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFV 310
Query: 292 QGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLA 351
+ LNIID +AI P+Y+ + +S S + + +G LRV+R +RIL + +L
Sbjct: 311 KNLLNIIDFVAILPFYLEVGLSGL--------SSKAARDVLGF-LRVVRFVRILRIFKLT 361
Query: 352 RHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRV--------LEFT 403
RH +GL+ LG T+R T EF LL++FLA+ + +F+ ++Y AE+ R +F
Sbjct: 362 RHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFK 421
Query: 404 SIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLE 463
+IP +WWA+++MTT+GYGDM P++ G +V L+G+L +A P I + F Y
Sbjct: 422 NIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSL 481
Query: 464 LKKEQEQLQARLRHL 478
+Q+ + R +H+
Sbjct: 482 AMAKQKLPKKRKKHV 496
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 206 bits (524), Expect = 4e-53
Identities = 150/495 (30%), Positives = 231/495 (46%), Gaps = 68/495 (13%)
Query: 43 RVRKVGALDASPVDLKKE---------ILINVGGRRYLLPWSTLDRFPLSRLSKLR---- 89
R RK G S LK+E I+INVGG R+ STL P +RL+ L
Sbjct: 11 RGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDG 70
Query: 90 --LCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEEL 147
+ V EFFFDR P F ++++ GKL ++C F+EEL
Sbjct: 71 GGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEEL 130
Query: 148 AYWGIEEAHLERCCLR--KLLRKLEEL-----------------EELAKLHREDVLRQQR 188
+WGI+E +E CC + R EE +E RE L++
Sbjct: 131 TFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLG 190
Query: 189 ETRRPASHSSRWGLCMN---RLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPD 245
A H + G C R+ + E+P S +V A S+ F+ + + C+ T
Sbjct: 191 PHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEA 250
Query: 246 LRAEEDQGECSRKCYYIFI--------------VETICVAWFSLEFCLRFVQAQDKCQFF 291
+ + E R + +E +CV WF+LEF +R V D F
Sbjct: 251 FNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFV 310
Query: 292 QGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLA 351
+ LNIID +AI P+Y+ + +S S + + +G LRV+R +RIL + +L
Sbjct: 311 KNLLNIIDFVAILPFYLEVGLSGL--------SSKAARDVLGF-LRVVRFVRILRIFKLT 361
Query: 352 RHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRV--------LEFT 403
RH +GL+ LG T+R T EF LL++FLA+ + +F+ ++Y AE+ R +F
Sbjct: 362 RHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFK 421
Query: 404 SIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLE 463
+IP +WWA+++MTT+GYGDM P++ G +V L+G+L +A P I + F Y
Sbjct: 422 NIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSL 481
Query: 464 LKKEQEQLQARLRHL 478
+Q+ + R +H+
Sbjct: 482 AMAKQKLPKKRKKHV 496
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 202 bits (514), Expect = 6e-52
Identities = 143/465 (30%), Positives = 225/465 (48%), Gaps = 57/465 (12%)
Query: 23 WSQLLSSPMETPSIKGLYYRRVRKVGALDASPVDLKKEILINVGGRRYLLPWSTLDRFPL 82
W + S PM P + R R AL I++NV G R+ TL+R+P
Sbjct: 19 WMPVASGPMPAPPRQ----ERKRTQDAL----------IVLNVSGTRFQTWQDTLERYPD 64
Query: 83 SRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALS 142
+ L R + Y ++Q++FFDR P F I++F GKL + C +
Sbjct: 65 TLLGSSE--RDFF--------YHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISA 114
Query: 143 FQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPASHSSRWGL 202
+ EELA++G+ + CC EE RE+ R Q + + S
Sbjct: 115 YDEELAFFGLIPEIIGDCCY----------EEYKDRRRENAERLQDDADTDTAGESALPT 164
Query: 203 CMNRLR--EMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGEC---SR 257
R R ENP + VF ++ F+A + ++ V T+P + E R
Sbjct: 165 MTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGER 224
Query: 258 KCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPP 317
F ++T CV F++E+ LR A + +F + ++IID++AI PYY+ L ++
Sbjct: 225 YAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMT---- 280
Query: 318 EDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLF 377
D E SG+ LR R+ + + +RHS GL+ LG T++ C E G LL
Sbjct: 281 -DNEDVSGAFV---------TLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFS 330
Query: 378 LAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALS 437
L +AI +F+ +++ AEK S +FTSIPA++W+ I++MTT+GYGDMVP+++ G++
Sbjct: 331 LTMAIIIFATVMFYAEKGSS-ASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSI 389
Query: 438 SILSGILIMAFPATSIFHTFS---HSYLELKKEQEQLQARLRHLQ 479
LSG+L++A P I FS H K + Q +ARL ++
Sbjct: 390 CSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIR 434
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 202 bits (513), Expect = 8e-52
Identities = 144/528 (27%), Positives = 229/528 (43%), Gaps = 91/528 (17%)
Query: 28 SSPMETPSIKGLYYRRVRKVGALDASPVDL-------KKEILINVGGRRYLLPWSTLDRF 80
+SP P+ +G RR L A+ + +I+INVGG R+ STL
Sbjct: 50 ASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTL 109
Query: 81 PLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCA 140
P +RL+ L E DYD + EFFFDR P F ++++ GKL ++C
Sbjct: 110 PGTRLAGLT-----EPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCG 164
Query: 141 LSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPASHSSR- 199
F+EEL +WGI+E +E CC + + E L D +H
Sbjct: 165 PLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGL 224
Query: 200 --------------------------------------------WGLCMNRLREMVENPQ 215
W R+ + E+P
Sbjct: 225 DDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPY 284
Query: 216 SGLPGKVFACLSILFVATTAVSLCVST-----------------MPDLRAEEDQGECSRK 258
S + A S+ F+ + + C+ T +P E
Sbjct: 285 SSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVET 344
Query: 259 CYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPE 318
++ VE +CV WF+ EF +R DK +F + LNIID +AI P+Y+ + +S +
Sbjct: 345 EPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSK 404
Query: 319 DGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFL 378
+ G LRV+R +RIL + +L RH +GL+ LG T+R T EF LL++FL
Sbjct: 405 AAKDVLG---------FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFL 455
Query: 379 AVAITLFSPLVYVAEK---ESGRVLE-----FTSIPASYWWAIISMTTVGYGDMVPRSVP 430
A+ + +F+ ++Y AE+ + +L F +IP +WWA+++MTT+GYGDM P++
Sbjct: 456 ALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWS 515
Query: 431 GQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHL 478
G +V L+G+L +A P I + F Y +Q+ + + +H+
Sbjct: 516 GMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHI 563
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 194 bits (494), Expect = 1e-49
Identities = 130/441 (29%), Positives = 211/441 (47%), Gaps = 59/441 (13%)
Query: 56 DLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDR 115
D + ++INV G R+ TL +FP + L Y +D E+FFDR
Sbjct: 173 DCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQY---------FDPLRNEYFFDR 223
Query: 116 S-PSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEE 174
+ PS ++ + + G+L + F EE+ ++ + E E
Sbjct: 224 NRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGE------------------EA 265
Query: 175 LAKLHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATT 234
L K ++ ++ E R + + + + + E P+S P + A +S+L + +
Sbjct: 266 LLKFREDEGFVREEEDRALPENEFKKQIWL-----LFEYPESSSPARGIAIVSVLVILIS 320
Query: 235 AVSLCVSTMPDLRAEED--------------------QGECSRKCYY---IFIVETICVA 271
V C+ T+P+ R + D E S + FIVET+C+
Sbjct: 321 IVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIV 380
Query: 272 WFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEK 331
WFS EF +R + FF+ +NIIDI++I PY+++L + G +G
Sbjct: 381 WFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGG--NGQQQQAM 438
Query: 332 VGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYV 391
+LR++R +R+ + +L+RHS GLQ LG T+R RE GLL+ FL + + LFS VY
Sbjct: 439 SFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYF 498
Query: 392 AEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPAT 451
AE + F SIP ++WWA+++MTTVGYGDM P +V G++V ++G+L +A P
Sbjct: 499 AEADEPTT-HFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVP 557
Query: 452 SIFHTFSHSYLELKKEQEQLQ 472
I F++ Y + +EQ Q
Sbjct: 558 VIVSNFNYFYHRETENEEQTQ 578
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 194 bits (494), Expect = 1e-49
Identities = 144/460 (31%), Positives = 215/460 (46%), Gaps = 74/460 (16%)
Query: 54 PVDLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFF 113
P + +++NV G R+ TL RFP + L + YD+ +E+FF
Sbjct: 8 PCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRF---------YDDARREYFF 58
Query: 114 DRS-PSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEEL 172
DR PS V+ + + G+L + F EE+A++G+ A L R
Sbjct: 59 DRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARL------------ 106
Query: 173 EELAKLHREDV---LRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSIL 229
RED + +R R A W L E P+S +V A +S+L
Sbjct: 107 -------REDEGCPVPPERPLPRRAFARQLWLL--------FEFPESSQAARVLAVVSVL 151
Query: 230 FVATTAVSLCVSTMPDLRAEED-----------------------QGECSRKCYY--IFI 264
+ + V C+ T+PD R + D G R + F+
Sbjct: 152 VILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFV 211
Query: 265 VETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPS 324
VET+C+ WFS E +R + K FF+ +N+ID +AI PY+V+L + R
Sbjct: 212 VETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGT------ELARQR 265
Query: 325 GSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITL 384
G +LRV+R +R+ + +L+RHS GLQ LG T+R RE GLL+ FL + + L
Sbjct: 266 GVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVL 325
Query: 385 FSPLVYVAEKESGRV-LEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGI 443
FS VY AE + RV FTSIP S+WWA+++MTTVGYGDM P +V G++V ++G+
Sbjct: 326 FSSAVYFAEVD--RVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGV 383
Query: 444 LIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHLQNTGP 483
L ++ P I FS+ Y + +E +Q GP
Sbjct: 384 LTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQPCGP 423
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,807,340
Number of Sequences: 37866
Number of extensions: 941469
Number of successful extensions: 4231
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 3729
Number of HSP's gapped (non-prelim): 357
length of query: 519
length of database: 18,247,518
effective HSP length: 107
effective length of query: 412
effective length of database: 14,195,856
effective search space: 5848692672
effective search space used: 5848692672
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.