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Search of human proteins with 27436988
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27436988 potassium voltage-gated channel, subfamily G,
member 1 [Homo sapiens]
(513 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27436988 potassium voltage-gated channel, subfamily G, member... 1030 0.0
gi|27436996 potassium voltage-gated channel, subfamily G, member... 565 e-161
gi|6912444 potassium voltage-gated channel, subfamily G, member ... 510 e-144
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 360 2e-99
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 356 2e-98
gi|27436993 potassium voltage-gated channel, subfamily G, member... 330 2e-90
gi|19071574 potassium voltage-gated channel, subfamily G, member... 326 4e-89
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 286 2e-77
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 284 2e-76
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 282 6e-76
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 281 1e-75
gi|20070166 potassium voltage-gated channel, subfamily F, member... 273 3e-73
gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens] 269 4e-72
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 236 3e-62
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 233 2e-61
gi|163792201 Shaw-related voltage-gated potassium channel protei... 233 2e-61
gi|24497460 Shaw-related voltage-gated potassium channel protein... 225 9e-59
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 224 2e-58
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 222 6e-58
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 222 6e-58
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 218 1e-56
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 218 1e-56
gi|21217561 Shaw-related voltage-gated potassium channel protein... 217 2e-56
gi|21217563 Shaw-related voltage-gated potassium channel protein... 217 2e-56
gi|24497458 Shaw-related voltage-gated potassium channel protein... 217 2e-56
gi|88758576 Shaw-related voltage-gated potassium channel protein... 216 3e-56
gi|24497462 Shaw-related voltage-gated potassium channel protein... 216 3e-56
gi|24497464 Shaw-related voltage-gated potassium channel protein... 216 3e-56
gi|119395748 potassium voltage-gated channel subfamily A member ... 214 1e-55
gi|25952092 potassium voltage-gated channel, shaker-related subf... 211 1e-54
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 1030 bits (2662), Expect = 0.0
Identities = 513/513 (100%), Positives = 513/513 (100%)
Query: 1 MTLLPGDNSDYDYSALSCTSDASFHPAFLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPED 60
MTLLPGDNSDYDYSALSCTSDASFHPAFLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPED
Sbjct: 1 MTLLPGDNSDYDYSALSCTSDASFHPAFLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPED 60
Query: 61 RRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRN 120
RRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRN
Sbjct: 61 RRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRN 120
Query: 121 PGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMV 180
PGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMV
Sbjct: 121 PGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMV 180
Query: 181 EREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVT 240
EREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVT
Sbjct: 181 EREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVT 240
Query: 241 AVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSP 300
AVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSP
Sbjct: 241 AVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSP 300
Query: 301 LTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHS 360
LTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHS
Sbjct: 301 LTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHS 360
Query: 361 LGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVI 420
LGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVI
Sbjct: 361 LGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVI 420
Query: 421 TMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFR 480
TMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFR
Sbjct: 421 TMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFR 480
Query: 481 RAQFLIKTKSQLSVSQDSDILFGSASSDTRDNN 513
RAQFLIKTKSQLSVSQDSDILFGSASSDTRDNN
Sbjct: 481 RAQFLIKTKSQLSVSQDSDILFGSASSDTRDNN 513
>gi|27436996 potassium voltage-gated channel, subfamily G, member 4
[Homo sapiens]
Length = 519
Score = 565 bits (1456), Expect = e-161
Identities = 280/447 (62%), Positives = 343/447 (76%), Gaps = 7/447 (1%)
Query: 34 AIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLK 93
+IKG +YRR +++ D P D ++ I+INVGG +Y LPW+TLD FPL+RL +L+
Sbjct: 35 SIKGLYYRRVRKVGALD-----ASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLR 89
Query: 94 ACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLY 153
C ++++I+ +CDDYD EFFFDR+P AFG I++FL AGKL LL+EMCALSFQEEL Y
Sbjct: 90 LCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAY 149
Query: 154 WGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRL 213
WGI E HL+ CC R+ L+K+EE E+ + ED + + R++ PA R G CM RL
Sbjct: 150 WGIEEAHLERCCLRKLLRKLEELEELAKLHRED--VLRQQRETRRPASHSSRWGLCMNRL 207
Query: 214 RDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVES 273
R+MVE P SGLPGKVFACLS+LFV TAV+L VST+P LR EE+QG CS+ C+ +FIVE+
Sbjct: 208 REMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVET 267
Query: 274 VCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNS 333
+CV WFSLEF LR +QA K F + PL +ID++AI PYY++L V + +G+S
Sbjct: 268 ICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSS 327
Query: 334 YLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAP 393
YL+KVGLVLRVLRALRILYVMRLARHSLGLQTLGLT RRCTREFGLLLLFL VAI LF+P
Sbjct: 328 YLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSP 387
Query: 394 LLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMA 453
L+YV E E EFTSIPA YWWA+I+MTTVGYGDMVPRS PGQ+VALSSILSGIL+MA
Sbjct: 388 LVYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMA 447
Query: 454 FPVTSIFHTFSRSYLELKQEQERVMFR 480
FP TSIFHTFS SYLELK+EQE++ R
Sbjct: 448 FPATSIFHTFSHSYLELKKEQEQLQAR 474
>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
[Homo sapiens]
Length = 466
Score = 510 bits (1313), Expect = e-144
Identities = 264/416 (63%), Positives = 321/416 (77%), Gaps = 9/416 (2%)
Query: 61 RRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRN 120
R R +IINVGG + L W L PL RL +L+AC DD+L VCDDYDV+ +EFFFDR+
Sbjct: 15 RARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRS 74
Query: 121 PGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMV 180
P AF I+ LRAGKLRLLR CAL+F++EL YWGI E L+ CC RR ++ EE AE
Sbjct: 75 PCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEAR 134
Query: 181 EREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVT 240
E A S R + GP GRL R RRLRD+V+ PHSGL GK+FAC+SV FV VT
Sbjct: 135 AGPTERGAQGSPAR-ALGP---RGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVT 190
Query: 241 AVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSP 300
AV L +ST+P +R EEE+G CS C ++F++E+VCV WFS EFLLR +QA SK AFLR+P
Sbjct: 191 AVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAP 250
Query: 301 LTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHS 360
L +ID++A+LP+Y++LL+ G AAG PG G L++ GLVLR+LRALR+LYVMRLARHS
Sbjct: 251 LNIIDILALLPFYVSLLL-GLAAG---PG-GTKLLERAGLVLRLLRALRVLYVMRLARHS 305
Query: 361 LGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVI 420
LGL++LGLT RRC REFGLLLLFLCVA+ALFAPL+++ E E+ +F+S+PA YWWAVI
Sbjct: 306 LGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVI 365
Query: 421 TMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQER 476
+MTTVGYGDMVPRS PGQVVALSSILSGILLMAFPVTSIFHTFSRSY ELK++Q+R
Sbjct: 366 SMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQR 421
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 360 bits (924), Expect = 2e-99
Identities = 181/423 (42%), Positives = 277/423 (65%), Gaps = 21/423 (4%)
Query: 63 RRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPG 122
RR+ INVGG+ + + W TLD P TRLG+L+ C + +L VCDDY++ NE+FFDR+PG
Sbjct: 35 RRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPG 94
Query: 123 AFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVER 182
AF +IL F R GKL ++ EMCALSF +EL YWGI E +L+ CC+ RY QK E+ E + R
Sbjct: 95 AFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRR 154
Query: 183 EEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAV 242
E E + EG + + + R ++L D++E+P+S + K+ A +S+LF+ ++ +
Sbjct: 155 EAE-TMREREGEEFDNTCCPDKR-----KKLWDLLEKPNSSVAAKILAIVSILFIVLSTI 208
Query: 243 NLSVSTLPSLREEEEQGHCS---QMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRS 299
LS++TLP L+E +E G + Q+ H VE+VC+ WF++E+LLR + +P+K+ F +
Sbjct: 209 ALSLNTLPELQETDEFGQLNDNRQLAH----VEAVCIAWFTMEYLLRFLSSPNKWKFFKG 264
Query: 300 PLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARH 359
PL +IDL+AILPYY+T+ + + V V+++ R +RIL +++LARH
Sbjct: 265 PLNVIDLLAILPYYVTIFL-------TESNKSVLQFQNVRRVVQIFRIMRILRILKLARH 317
Query: 360 SLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAV 419
S GLQ+LG T RR E GLL+LFL + I +F+ L++ E + D+ +FTSIPA +WWA
Sbjct: 318 STGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKD-EDATKFTSIPASFWWAT 376
Query: 420 ITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMF 479
ITMTTVGYGD+ P++ G++V ++G+L++A P+ I + FS Y E K++++ +
Sbjct: 377 ITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKR 436
Query: 480 RRA 482
R A
Sbjct: 437 REA 439
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 356 bits (914), Expect = 2e-98
Identities = 180/435 (41%), Positives = 277/435 (63%), Gaps = 21/435 (4%)
Query: 51 EPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDV 110
EP + + + RR+ +NVGG+ + + W TLD P TRLG+L+ C D +L VCDDY +
Sbjct: 19 EPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDYSL 78
Query: 111 TCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYL 170
NE+FFDR+PGAF +IL F R G+L ++ EMCALSF +EL YWGI E +L+ CC+ RY
Sbjct: 79 DDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYH 138
Query: 171 QKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFA 230
QK E+ E ++RE E + EG + + E R ++L D++E+P+S + K+ A
Sbjct: 139 QKKEQMNEELKREAE-TLREREGEEFDNTCCAEKR-----KKLWDLLEKPNSSVAAKILA 192
Query: 231 CLSVLFVTVTAVNLSVSTLPSLREEEEQGHCS---QMCHNVFIVESVCVGWFSLEFLLRL 287
+S++F+ ++ + LS++TLP L+ +E G + Q+ H VE+VC+ WF++E+LLR
Sbjct: 193 IISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAH----VEAVCIAWFTMEYLLRF 248
Query: 288 IQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRA 347
+ +P K+ F + PL IDL+AILPYY+T+ + + V V+++ R
Sbjct: 249 LSSPKKWKFFKGPLNAIDLLAILPYYVTIFL-------TESNKSVLQFQNVRRVVQIFRI 301
Query: 348 LRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPE 407
+RIL +++LARHS GLQ+LG T RR E GLL+LFL + I +F+ L++ E + D +
Sbjct: 302 MRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKD-EDDTK 360
Query: 408 FTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSY 467
F SIPA +WWA ITMTTVGYGD+ P++ G++V ++G+L++A P+ I + FS Y
Sbjct: 361 FKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFY 420
Query: 468 LELKQEQERVMFRRA 482
E K++++ + R A
Sbjct: 421 KEQKRQEKAIKRREA 435
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 330 bits (845), Expect = 2e-90
Identities = 176/417 (42%), Positives = 256/417 (61%), Gaps = 18/417 (4%)
Query: 65 IIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAF 124
+++NVGG +YSL L +FPL R+ +L C + D+L VCDDYD NE+FFDR+ AF
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 125 GTILTFLRA-GKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVERE 183
G IL ++R GKLR MC LSF E++YWG+ HL+ CC+RR ++ + +
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 184 EEDDALDSEGRDSEGPAEGEGRLGR-CMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAV 242
E GRD P E R + R+R E P S L ++ A +SV+FV V+ V
Sbjct: 131 EPGVL----GRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMV 186
Query: 243 NLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLT 302
L STLP R + I+E++C+GWF+ E ++R I + +K F++ PL
Sbjct: 187 VLCASTLPDWRNAAADNR--SLDDRSRIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLN 244
Query: 303 LIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLG 362
+IDL+AI PYYI++L+ NS L + G+ LRVLR +RI +V++LARH +G
Sbjct: 245 IIDLLAITPYYISVLMTVFTGE-------NSQLQRAGVTLRVLRMMRIFWVIKLARHFIG 297
Query: 363 LQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEM---ADSPEFTSIPACYWWAV 419
LQTLGLT +RC RE +LL+F+CVA+A+F+ L ++E+ + + +FTSIPA WW +
Sbjct: 298 LQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVI 357
Query: 420 ITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQER 476
I+MTTVGYGDM P + PG+++ ++SGI+L+A P+T I+H+F + Y ELK R
Sbjct: 358 ISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSAR 414
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 326 bits (835), Expect = 4e-89
Identities = 176/426 (41%), Positives = 258/426 (60%), Gaps = 25/426 (5%)
Query: 65 IIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAF 124
+++NVGG +YSL L +FPL R+ +L C + D+L VCDDYD NE+FFDR+ AF
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 125 GTILTFLRA-GKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVERE 183
G IL ++R GKLR MC LSF E++YWG+ HL+ CC+RR ++ + +
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 184 EEDDALDSEGRDSEGPAEGEGRLGR-CMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAV 242
E GRD P E R + R+R E P S L ++ A +SV+FV V+ V
Sbjct: 131 EPGVL----GRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMV 186
Query: 243 NLSVSTLPSLR---------EEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSK 293
L STLP R ++ + I+E++C+GWF+ E ++R I + +K
Sbjct: 187 VLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIVRFIVSKNK 246
Query: 294 FAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYV 353
F++ PL +IDL+AI PYYI++L+ NS L + G+ LRVLR +RI +V
Sbjct: 247 CEFVKRPLNIIDLLAITPYYISVLMTVFTGE-------NSQLQRAGVTLRVLRMMRIFWV 299
Query: 354 MRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEM---ADSPEFTS 410
++LARH +GLQTLGLT +RC RE +LL+F+CVA+A+F+ L ++E+ + + +FTS
Sbjct: 300 IKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTS 359
Query: 411 IPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLEL 470
IPA WW +I+MTTVGYGDM P + PG+++ ++SGI+L+A P+T I+H+F + Y EL
Sbjct: 360 IPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHEL 419
Query: 471 KQEQER 476
K R
Sbjct: 420 KFRSAR 425
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 286 bits (733), Expect = 2e-77
Identities = 160/427 (37%), Positives = 236/427 (55%), Gaps = 34/427 (7%)
Query: 67 INVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGT 126
+NVGG++ L L FP TRLG+L+A + + +CDDYD EF+FDR+PG F +
Sbjct: 54 VNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPGFFLS 113
Query: 127 ILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEED 186
+L F R G L +L E+C +F +E YWG+ E+ L CC+ RYL++ + + D
Sbjct: 114 LLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARYLER-----RLTQPHAWD 168
Query: 187 DALDSEGRDSEGPAE-----------GEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVL 235
+ D+ P E G R GR RRL +E P LP K+F+C+S+
Sbjct: 169 EDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSIS 228
Query: 236 FVTVTAVNLSVSTLPSLREEEEQGHCSQMCHN-----------VFIVESVCVGWFSLEFL 284
V + + + +LP + E + + + +E C+ WFS E
Sbjct: 229 VVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSFEVS 288
Query: 285 LRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRV 344
RL+ APS F PL LID+V++LP+Y+TLL G A G + G +G V++V
Sbjct: 289 SRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLA-GVALGDQ----GGKEFGHLGKVVQV 343
Query: 345 LRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMAD 404
R +RI V++LARHS GL++LG T + RE G+LLL+L V +++F+ + Y E E +
Sbjct: 344 FRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKE--E 401
Query: 405 SPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFS 464
F +IPAC+WW ++MTTVGYGD+VP + G++ A IL GIL++A P+T IF+ FS
Sbjct: 402 DVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFS 461
Query: 465 RSYLELK 471
Y K
Sbjct: 462 HFYRRQK 468
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 284 bits (726), Expect = 2e-76
Identities = 163/429 (37%), Positives = 253/429 (58%), Gaps = 34/429 (7%)
Query: 67 INVGGIKYSLPWTTLDEFPLTRLGQLK----------ACTNFDDILNVCDDYDVTCNEFF 116
+NVGG ++ L L FP TRLG+L A L +CDD + NE+F
Sbjct: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
Query: 117 FDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEF 176
FDR+ AF +L + R G+L ++ ++CALSF +E+ YWGI E +D CC+ RY ++ +E
Sbjct: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRR-KEL 161
Query: 177 AEMVEREEEDDALDSEGRDSEGPAEGEGRLGRC---MRRLRDMVERPHSGLPGKVFACLS 233
+E ++ ++ D+E ++S+ +E + G C ++L +++E+P S ++F +S
Sbjct: 162 SETLDFKK-----DTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVIS 216
Query: 234 VLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSK 293
++FV V+ +N+ +L E Q+ I+E VC+ WF+ EF+LR + +
Sbjct: 217 IIFVVVSIINM------ALMSAELSWLDLQLLE---ILEYVCISWFTGEFVLRFLCVRDR 267
Query: 294 FAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYV 353
FLR +IDL+AILP+YITLLV+ + + L+ VG +++VLR LR L +
Sbjct: 268 CRFLRKVPNIIDLLAILPFYITLLVESLSGSQT-----TQELENVGRIVQVLRLLRALRM 322
Query: 354 MRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPA 413
++L RHS GL++LG+T +C E GLLLLFL V I++F+ + Y E + D+ FTS+P
Sbjct: 323 LKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDT-TFTSVPC 381
Query: 414 CYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQE 473
+WWA +MTTVGYGD+ P +T G++VA ILSGIL++A P+ I FS Y LK +
Sbjct: 382 AWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLK 441
Query: 474 QERVMFRRA 482
+ V R A
Sbjct: 442 EAAVRQREA 450
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 282 bits (721), Expect = 6e-76
Identities = 164/419 (39%), Positives = 244/419 (58%), Gaps = 26/419 (6%)
Query: 65 IIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAF 124
I INVGG K L TL FP TRLG+L C + + IL +CDDYD EF+FDRNP F
Sbjct: 19 IRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELF 78
Query: 125 GTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYL-QKIEEFAEMVERE 183
+L F GKL ++ E+C SF +E+ YWGI E +D CC Y +K+E E+E
Sbjct: 79 PYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEP-----EQE 133
Query: 184 EEDDALDSEGRDS---------EGPAEGEGR-LGRCMRRLRDMVERPHSGLPGKVFACLS 233
+ D+ D E S ++ +G+ LG R+L ++ P + +VF+ LS
Sbjct: 134 KWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILS 193
Query: 234 VLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSK 293
+L V + + + +++LP + + QG+ + IVE + WF+ E + R AP
Sbjct: 194 ILVVMGSIITMCLNSLPDFQIPDSQGNPGE-DPRFEIVEHFGIAWFTFELVARFAVAPDF 252
Query: 294 FAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYV 353
F ++ L LIDL++I+P+YITL+V+ L +G V +VLR +RI +
Sbjct: 253 LKFFKNALNLIDLMSIVPFYITLVVNLVV-------ESTPTLANLGRVAQVLRLMRIFRI 305
Query: 354 MRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPA 413
++LARHS GL++LG T + +E GLLLL+L V I++F+ + Y IE E ++ +IPA
Sbjct: 306 LKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKE--ENEGLATIPA 363
Query: 414 CYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQ 472
C+WWA ++MTTVGYGD+VP +T G++ A + IL+GIL++ P+T IF+ FS Y KQ
Sbjct: 364 CWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQ 422
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 281 bits (718), Expect = 1e-75
Identities = 159/421 (37%), Positives = 243/421 (57%), Gaps = 18/421 (4%)
Query: 57 QPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFF 116
+P + +NVGG K S+ +TL FP TRLG+L C + + IL +CDDY V E++
Sbjct: 9 RPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYY 68
Query: 117 FDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEF 176
FDRNP F +L F GKL ++ E+C SF +E+ YWGI E +D CC RY ++ EE
Sbjct: 69 FDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEEN 128
Query: 177 AEM-VEREEEDDALDSEGRDS-----EGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFA 230
E +++ D + DS +S E R G+ +++ +E P L K+ A
Sbjct: 129 HEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIA 188
Query: 231 CLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQA 290
S+ V + V + V ++ + E+ + + VE C+ WF+ E +RL A
Sbjct: 189 ISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEG----VEIACIAWFTGELAVRLAAA 244
Query: 291 PSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRI 350
P + F ++PL +ID V+I+P+Y TL VD + ++ +G V+++LR +RI
Sbjct: 245 PCQKKFWKNPLNIIDFVSIIPFYATLAVD-------TKEEESEDIENMGKVVQILRLMRI 297
Query: 351 LYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTS 410
+++LARHS+GL++LG T R E GLLLLFL V I++F+ L+Y +E + S TS
Sbjct: 298 FRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTS-SLTS 356
Query: 411 IPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLEL 470
IP C+WWA I+MTTVGYGD P + G+++A + I+ GIL++A P+T IF+ FS+ Y +
Sbjct: 357 IPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQ 416
Query: 471 K 471
K
Sbjct: 417 K 417
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 273 bits (698), Expect = 3e-73
Identities = 159/446 (35%), Positives = 255/446 (57%), Gaps = 24/446 (5%)
Query: 65 IIINVGGIKYSLPWTTLDEFPLTRLGQLKACT--NFDDILNVCDDYDVTCNEFFFDRNPG 122
I++NVGG++ L L ++P TRL +L C +D I ++CDDYD EF+FDR+P
Sbjct: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 84
Query: 123 AFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVER 182
AF ++ G++ + + +C + F+ E+ +W + LD CCK +K EE E+ R
Sbjct: 85 AFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARR 144
Query: 183 EEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAV 242
+ LD G D+ EGR RC + + +E+P S P +V A LS L + V++V
Sbjct: 145 VQL--ILDDLGVDA-----AEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSV 197
Query: 243 NLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLT 302
+ + T+P L+ + +G+ + + VE+ C+GWF+LE+LLRL +P+K F S +
Sbjct: 198 VMCMGTIPELQVLDAEGNRVEH-PTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMN 256
Query: 303 LIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLG 362
++D++AILP+Y++L + GA L V ++ LR +RI + +LARHS G
Sbjct: 257 IVDVLAILPFYVSLTLTHL-------GARMMELTNVQQAVQALRIMRIARIFKLARHSSG 309
Query: 363 LQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITM 422
LQTL +R +E GLLL++L V I +F+ L Y +E ++ F SIP +WWA+ITM
Sbjct: 310 LQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPET-LFKSIPQSFWWAIITM 368
Query: 423 TTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRA 482
TTVGYGD+ P++T G++ A S L G++ +A P+ I + F R Y ++RV+ A
Sbjct: 369 TTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYY-----NKQRVLETAA 423
Query: 483 QFLIKTKSQLSVSQDSDILFGSASSD 508
+ ++ +L+ S + G + SD
Sbjct: 424 KHELEL-MELNSSSGGEGKTGGSRSD 448
>gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]
Length = 545
Score = 269 bits (688), Expect = 4e-72
Identities = 149/406 (36%), Positives = 235/406 (57%), Gaps = 3/406 (0%)
Query: 67 INVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGT 126
+NVGG Y L + L FP TRLG+L T+ L++CDDY+ +E+FFDR+P F
Sbjct: 101 VNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVFQL 160
Query: 127 ILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEED 186
+ F +G L +L +C F EEL YWG+ + CC+ + ++ +E +E ++ + E
Sbjct: 161 VYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQHEL 220
Query: 187 DALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSV 246
A ++ ++E G RRL +++E+P S + K S FV V+ V L++
Sbjct: 221 RA-QAQVEEAEELFRDMRFYGPQRRRLWNLMEKPFSSVAAKAIGVASSTFVLVSVVALAL 279
Query: 247 STLPSLREEEEQGHCSQMCHNVFI-VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLID 305
+T+ +++ QG + VE +C+G+F+LE+LLRL P F RS L L+D
Sbjct: 280 NTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRRFARSALNLVD 339
Query: 306 LVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQT 365
LVAILP Y+ LL++ + G + KVG VLRV+R +RI +++LARHS GL+
Sbjct: 340 LVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQVLRVMRLMRIFRILKLARHSTGLRA 399
Query: 366 LGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTV 425
G T R+C ++ G LLLF+ + I F+ +Y +E+++ S FT+IP +WWA ++++TV
Sbjct: 400 FGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHDV-PSTNFTTIPHSWWWAAVSISTV 458
Query: 426 GYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELK 471
GYGDM P + G+ A I GI+L P++ +++ FS Y +LK
Sbjct: 459 GYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLK 504
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 236 bits (603), Expect = 3e-62
Identities = 158/460 (34%), Positives = 232/460 (50%), Gaps = 44/460 (9%)
Query: 28 FLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLT 87
+LP +A + AQ+ P P G + +++NV G ++ TLD +P T
Sbjct: 8 WLPFARAAAVGWLPLAQQPLP---PAPGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDT 64
Query: 88 RLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSF 147
LG + F YD E+FFDR+P F +L F R G+L R+ C +F
Sbjct: 65 LLGSSEK--EFF--------YDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAF 114
Query: 148 QEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLG 207
EEL ++G+ + + CC Y + +E AE + +EE + + +GPA G
Sbjct: 115 DEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAE------QAGDGPALPAGSSL 168
Query: 208 RCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLP---SLREEEEQGHCSQM 264
R +RL E PH+ VF ++ F+ V+ + V T+P S R + C +
Sbjct: 169 R--QRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGER 226
Query: 265 CHNVFI-VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAA 323
F +++ CV F+ E+LLRL APS+ FLRS ++LID+VAILPYYI LLV
Sbjct: 227 FPQAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKN-- 284
Query: 324 GRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLF 383
D V LR R+ + + +RHS GL+ LG T + C E G LL
Sbjct: 285 ------------DDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFS 332
Query: 384 LCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALS 443
L +AI +FA +++ E + FTSIPA +W+ ++TMTT+GYGDMVP + G++
Sbjct: 333 LTMAIIIFATVMFYAEKG-TNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSI 391
Query: 444 SILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQ 483
LSG+L++A PV I FSR Y + +R RRAQ
Sbjct: 392 CSLSGVLVIALPVPVIVSNFSRIY----HQNQRADKRRAQ 427
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 233 bits (595), Expect = 2e-61
Identities = 152/457 (33%), Positives = 228/457 (49%), Gaps = 67/457 (14%)
Query: 60 DRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLK---ACTNFDDILNVCDDYDVTCNEFF 116
D RI+INVGG ++ +TL P TRL L A ++FD YD +EFF
Sbjct: 5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFD--------YDPRADEFF 56
Query: 117 FDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQ----- 171
FDR+PG F IL + R GKL ++C ++EEL +WGI E ++ CC Y Q
Sbjct: 57 FDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAE 116
Query: 172 -KIEEFAEMVEREEEDDALDSEGRDSEGPAEGE--------------GRLGRCMRRLRDM 216
++ F DDA D++G G E E GR G RR +
Sbjct: 117 EALDSFGGAPLDNSADDA-DADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPR 175
Query: 217 V----ERPHSGLPGKVFACLSVLFVTVTAVNLSVST------------LPSLREEEEQGH 260
+ E P+S + A S+ F+ V+ + T + ++R + +
Sbjct: 176 IWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRY 235
Query: 261 CSQMCHNVFI--VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLV 318
+ F+ +E VCV WF+ EFL+R+I P+K F+++ L +ID VAILP+Y+ + +
Sbjct: 236 YREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGL 295
Query: 319 DGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFG 378
G ++ K G LRV+R +RIL + +L RH +GL+ LG T R T EF
Sbjct: 296 SGLSSKAAKDVLG---------FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 346
Query: 379 LLLLFLCVAIALFAPLLYVIEN--------EMADSPEFTSIPACYWWAVITMTTVGYGDM 430
LL++FL + + +FA ++Y E ++ F +IP +WWAV+TMTT+GYGDM
Sbjct: 347 LLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDM 406
Query: 431 VPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSY 467
P++ G +V L+G+L +A PV I + F Y
Sbjct: 407 YPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 233 bits (595), Expect = 2e-61
Identities = 152/457 (33%), Positives = 228/457 (49%), Gaps = 67/457 (14%)
Query: 60 DRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLK---ACTNFDDILNVCDDYDVTCNEFF 116
D RI+INVGG ++ +TL P TRL L A ++FD YD +EFF
Sbjct: 5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFD--------YDPRADEFF 56
Query: 117 FDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQ----- 171
FDR+PG F IL + R GKL ++C ++EEL +WGI E ++ CC Y Q
Sbjct: 57 FDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAE 116
Query: 172 -KIEEFAEMVEREEEDDALDSEGRDSEGPAEGE--------------GRLGRCMRRLRDM 216
++ F DDA D++G G E E GR G RR +
Sbjct: 117 EALDSFGGAPLDNSADDA-DADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPR 175
Query: 217 V----ERPHSGLPGKVFACLSVLFVTVTAVNLSVST------------LPSLREEEEQGH 260
+ E P+S + A S+ F+ V+ + T + ++R + +
Sbjct: 176 IWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRY 235
Query: 261 CSQMCHNVFI--VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLV 318
+ F+ +E VCV WF+ EFL+R+I P+K F+++ L +ID VAILP+Y+ + +
Sbjct: 236 YREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGL 295
Query: 319 DGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFG 378
G ++ K G LRV+R +RIL + +L RH +GL+ LG T R T EF
Sbjct: 296 SGLSSKAAKDVLG---------FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 346
Query: 379 LLLLFLCVAIALFAPLLYVIEN--------EMADSPEFTSIPACYWWAVITMTTVGYGDM 430
LL++FL + + +FA ++Y E ++ F +IP +WWAV+TMTT+GYGDM
Sbjct: 347 LLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDM 406
Query: 431 VPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSY 467
P++ G +V L+G+L +A PV I + F Y
Sbjct: 407 YPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 225 bits (573), Expect = 9e-59
Identities = 155/475 (32%), Positives = 224/475 (47%), Gaps = 88/475 (18%)
Query: 64 RIIINVGGIKYSLPWTTLDEFPLTRLGQL---KACTNFDDILNVCDDYDVTCNEFFFDRN 120
+I+INVGG+++ +TL P TRL L +A FD YD +EFFFDR+
Sbjct: 89 KIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFD--------YDPGADEFFFDRH 140
Query: 121 PGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQK--IEEFAE 178
PG F +L + R GKL ++C F+EEL +WGI E ++ CC Y Q EE +
Sbjct: 141 PGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALD 200
Query: 179 MVEREE-------------EDDALDSE-----------------------GRDSEGPAEG 202
E + D LD E G + GP G
Sbjct: 201 SFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGG 260
Query: 203 EGRLG-----RCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVN---------LSVST 248
G G R R+ + E P+S + A S+ F+ ++ + +S
Sbjct: 261 AGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISN 320
Query: 249 LPSLREEEEQGHCSQMCHNVFI--------VESVCVGWFSLEFLLRLIQAPSKFAFLRSP 300
+ G + NV + VE VCV WF+ EFL+R+ P K FL+S
Sbjct: 321 KTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSS 380
Query: 301 LTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHS 360
L +ID VAILP+Y+ + + G ++ K G LRV+R +RIL + +L RH
Sbjct: 381 LNIIDCVAILPFYLEVGLSGLSSKAAKDVLG---------FLRVVRFVRILRIFKLTRHF 431
Query: 361 LGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPE--------FTSIP 412
+GL+ LG T R T EF LL++FL + + +FA ++Y E AD + F +IP
Sbjct: 432 VGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIP 491
Query: 413 ACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSY 467
+WWAV+TMTT+GYGDM P++ G +V L+G+L +A PV I + F Y
Sbjct: 492 IGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 546
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 224 bits (570), Expect = 2e-58
Identities = 148/437 (33%), Positives = 223/437 (51%), Gaps = 53/437 (12%)
Query: 58 PEDRRRR-----IIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTC 112
P R+R I++NV G ++ TL+ +P T LG + D Y
Sbjct: 31 PRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLGSSER-----DFF-----YHPET 80
Query: 113 NEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQK 172
++FFDR+P F IL F R GKL R C ++ EEL ++G+ + + CC Y +
Sbjct: 81 QQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDR 140
Query: 173 IEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACL 232
E AE R ++D D+ G + R+ R E PH+ VF +
Sbjct: 141 RRENAE---RLQDDADTDTAGESALPTMTARQRVWRAF-------ENPHTSTMALVFYYV 190
Query: 233 SVLFVTVTAVNLSVSTLPSLREEEEQGHCSQM-CHN-----VFIVESVCVGWFSLEFLLR 286
+ F+ V+ + V T+P GH ++ C F +++ CV F++E+LLR
Sbjct: 191 TGFFIAVSVIANVVETVPC---GSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYLLR 247
Query: 287 LIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLR 346
L APS++ F+RS +++ID+VAILPYYI L++ N + + LRV R
Sbjct: 248 LAAAPSRYRFVRSVMSIIDVVAILPYYIGLVM-----------TDNEDVSGAFVTLRVFR 296
Query: 347 ALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSP 406
RI + +RHS GL+ LG T + C E G LL L +AI +FA +++ E + S
Sbjct: 297 VFRIF---KFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSAS- 352
Query: 407 EFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRS 466
+FTSIPA +W+ ++TMTT+GYGDMVP++ G++ LSG+L++A PV I FSR
Sbjct: 353 KFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRI 412
Query: 467 YLELKQEQERVMFRRAQ 483
Y + +R RRAQ
Sbjct: 413 Y----HQNQRADKRRAQ 425
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 222 bits (566), Expect = 6e-58
Identities = 145/432 (33%), Positives = 223/432 (51%), Gaps = 46/432 (10%)
Query: 58 PEDRRRR----IIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCN 113
P D+ +R I++NV G ++ TTL+ +P T LG + F++
Sbjct: 31 PADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNE----------DTK 80
Query: 114 EFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKI 173
E+FFDR+P F +L F R GKL R C ++ +EL ++GI + + CC Y +
Sbjct: 81 EYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRK 140
Query: 174 EEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLS 233
E AE + + DSE E L R E PH+ VF ++
Sbjct: 141 RENAERL----------MDDNDSENNQESMPSLSFRQTMWRAF-ENPHTSTLALVFYYVT 189
Query: 234 VLFVTVTAVNLSVSTLP--SLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAP 291
F+ V+ + V T+P ++ +E + F +++ CV F++E+LLRL AP
Sbjct: 190 GFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAP 249
Query: 292 SKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRIL 351
S++ F+RS +++ID+VAI+PYYI L++ N + + LRV R RI
Sbjct: 250 SRYRFIRSVMSIIDVVAIMPYYIGLVM-----------TNNEDVSGAFVTLRVFRVFRIF 298
Query: 352 YVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSI 411
+ +RHS GL+ LG T + C E G LL L +AI +FA +++ E + S +FTSI
Sbjct: 299 ---KFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSAS-KFTSI 354
Query: 412 PACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELK 471
PA +W+ ++TMTT+GYGDMVP++ G++ LSG+L++A PV I FSR Y
Sbjct: 355 PASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY---- 410
Query: 472 QEQERVMFRRAQ 483
+ +R RRAQ
Sbjct: 411 HQNQRADKRRAQ 422
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 222 bits (566), Expect = 6e-58
Identities = 145/432 (33%), Positives = 223/432 (51%), Gaps = 46/432 (10%)
Query: 58 PEDRRRR----IIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCN 113
P D+ +R I++NV G ++ TTL+ +P T LG + F++
Sbjct: 31 PADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNE----------DTK 80
Query: 114 EFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKI 173
E+FFDR+P F +L F R GKL R C ++ +EL ++GI + + CC Y +
Sbjct: 81 EYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRK 140
Query: 174 EEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLS 233
E AE + + DSE E L R E PH+ VF ++
Sbjct: 141 RENAERL----------MDDNDSENNQESMPSLSFRQTMWRAF-ENPHTSTLALVFYYVT 189
Query: 234 VLFVTVTAVNLSVSTLP--SLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAP 291
F+ V+ + V T+P ++ +E + F +++ CV F++E+LLRL AP
Sbjct: 190 GFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAP 249
Query: 292 SKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRIL 351
S++ F+RS +++ID+VAI+PYYI L++ N + + LRV R RI
Sbjct: 250 SRYRFIRSVMSIIDVVAIMPYYIGLVM-----------TNNEDVSGAFVTLRVFRVFRIF 298
Query: 352 YVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSI 411
+ +RHS GL+ LG T + C E G LL L +AI +FA +++ E + S +FTSI
Sbjct: 299 ---KFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSAS-KFTSI 354
Query: 412 PACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELK 471
PA +W+ ++TMTT+GYGDMVP++ G++ LSG+L++A PV I FSR Y
Sbjct: 355 PASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY---- 410
Query: 472 QEQERVMFRRAQ 483
+ +R RRAQ
Sbjct: 411 HQNQRADKRRAQ 422
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 218 bits (555), Expect = 1e-56
Identities = 155/462 (33%), Positives = 232/462 (50%), Gaps = 72/462 (15%)
Query: 46 LRPQDEPRQGCQP---EDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDIL 102
L PQDE G D R++INV G+++ TL +FP T LG + T + D L
Sbjct: 156 LLPQDEGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPL 215
Query: 103 NVCDDYDVTCNEFFFDRNPGAFGTILTFLRAG-KLRLLREMCALSFQEELLYWGIAEDHL 161
NE+FFDRN +F IL + ++G +L+ + F EE+ ++ + E+ L
Sbjct: 216 R---------NEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEAL 266
Query: 162 DGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPH 221
K E V REEED AL E E + +++ + E P
Sbjct: 267 ---------LKFREDEGFV-REEEDRALP----------ENEFK-----KQIWLLFEYPE 301
Query: 222 SGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEE------------------QGHCSQ 263
S P + A +SVL + ++ V + TLP R++ + H
Sbjct: 302 SSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLEN 361
Query: 264 MCHNVF-----IVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLV 318
H +F IVE+VC+ WFS EF++R PS+ F ++ + +ID+V+ILPY+ITL
Sbjct: 362 SGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGT 421
Query: 319 DGAAAGRRKPGAGNSYLDKVG--LVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTRE 376
D A ++ G GN + +LR++R +R+ + +L+RHS GLQ LG T R RE
Sbjct: 422 DLA----QQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRE 477
Query: 377 FGLLLLFLCVAIALFAPLLYVIENEMADSP--EFTSIPACYWWAVITMTTVGYGDMVPRS 434
GLL+ FL + + LF+ +Y E AD P F SIP +WWAV+TMTTVGYGDM P +
Sbjct: 478 LGLLIFFLFIGVILFSSAVYFAE---ADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPIT 534
Query: 435 TPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQER 476
G++V ++G+L +A PV I F+ Y + +E+
Sbjct: 535 VGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQ 576
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 218 bits (555), Expect = 1e-56
Identities = 140/436 (32%), Positives = 224/436 (51%), Gaps = 60/436 (13%)
Query: 64 RIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGA 123
R++IN+ G+++ TL +FP T LG K + D L NE+FFDRN +
Sbjct: 34 RVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLR---------NEYFFDRNRPS 84
Query: 124 FGTILTFLRAG-KLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVER 182
F IL + ++G +LR + F EE+ ++ + E+ ++ + R
Sbjct: 85 FDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAME-----------------MFR 127
Query: 183 EEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAV 242
E+E + E E + R++ + E P S P ++ A +SV+ + ++ V
Sbjct: 128 EDEGYIKEEERPLPENEFQ---------RQVWLLFEYPESSGPARIIAIVSVMVILISIV 178
Query: 243 NLSVSTLPSLREEEEQGHCSQMCHNV------------------FIVESVCVGWFSLEFL 284
+ + TLP R+E E H S + + FIVE++C+ WFS EFL
Sbjct: 179 SFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFL 238
Query: 285 LRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGL-VLR 343
+R PSK F + + +ID+VAI+PY+ITL + A KP + L +LR
Sbjct: 239 VRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELA----EKPEDAQQGQQAMSLAILR 294
Query: 344 VLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMA 403
V+R +R+ + +L+RHS GLQ LG T + RE GLL+ FL + + LF+ +Y E +
Sbjct: 295 VIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADER 354
Query: 404 DSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTF 463
+S +F SIP +WWAV++MTTVGYGDMVP + G++V ++G+L +A PV I F
Sbjct: 355 ES-QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNF 413
Query: 464 SRSYLELKQEQERVMF 479
+ Y + +E+ +
Sbjct: 414 NYFYHRETEGEEQAQY 429
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 217 bits (553), Expect = 2e-56
Identities = 145/486 (29%), Positives = 223/486 (45%), Gaps = 88/486 (18%)
Query: 60 DRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVC-------------- 105
+ R+I+NVGG ++ +TL P TRL L + D L
Sbjct: 5 ENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPP 64
Query: 106 ----------------------------DDYDVTCNEFFFDRNPGAFGTILTFLRAGKLR 137
D+ EFFFDR+PG F +L + R GKL
Sbjct: 65 PRAPPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLH 124
Query: 138 LLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSE 197
++C F+EEL +WGI E ++ CC Y Q + E ++ E D + + D E
Sbjct: 125 CPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH-RDAEEALDIFETPDLIGGDPGDDE 183
Query: 198 ----------------GPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTA 241
GP GR R R+ + E P+S + A S+ F+ V+
Sbjct: 184 DLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSI 243
Query: 242 VNLSVST------LPSLREEEEQGHCSQMCHNV------FIVESVCVGWFSLEFLLRLIQ 289
+ T + + E G + + + VE VCV WF+ EFL+R++
Sbjct: 244 TTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVF 303
Query: 290 APSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALR 349
+P+K F+++ L +ID VAILP+Y+ + + G ++ K G LRV+R +R
Sbjct: 304 SPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLG---------FLRVVRFVR 354
Query: 350 ILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIEN--------E 401
IL + +L RH +GL+ LG T R T EF LL++FL + + +FA ++Y E
Sbjct: 355 ILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPS 414
Query: 402 MADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFH 461
++ +F +IP +WWAV+TMTT+GYGDM P++ G +V L+G+L +A PV I +
Sbjct: 415 ASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVN 474
Query: 462 TFSRSY 467
F Y
Sbjct: 475 NFGMYY 480
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 217 bits (553), Expect = 2e-56
Identities = 145/486 (29%), Positives = 223/486 (45%), Gaps = 88/486 (18%)
Query: 60 DRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVC-------------- 105
+ R+I+NVGG ++ +TL P TRL L + D L
Sbjct: 5 ENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPP 64
Query: 106 ----------------------------DDYDVTCNEFFFDRNPGAFGTILTFLRAGKLR 137
D+ EFFFDR+PG F +L + R GKL
Sbjct: 65 PRAPPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLH 124
Query: 138 LLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSE 197
++C F+EEL +WGI E ++ CC Y Q + E ++ E D + + D E
Sbjct: 125 CPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH-RDAEEALDIFETPDLIGGDPGDDE 183
Query: 198 ----------------GPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTA 241
GP GR R R+ + E P+S + A S+ F+ V+
Sbjct: 184 DLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSI 243
Query: 242 VNLSVST------LPSLREEEEQGHCSQMCHNV------FIVESVCVGWFSLEFLLRLIQ 289
+ T + + E G + + + VE VCV WF+ EFL+R++
Sbjct: 244 TTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVF 303
Query: 290 APSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALR 349
+P+K F+++ L +ID VAILP+Y+ + + G ++ K G LRV+R +R
Sbjct: 304 SPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLG---------FLRVVRFVR 354
Query: 350 ILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIEN--------E 401
IL + +L RH +GL+ LG T R T EF LL++FL + + +FA ++Y E
Sbjct: 355 ILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPS 414
Query: 402 MADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFH 461
++ +F +IP +WWAV+TMTT+GYGDM P++ G +V L+G+L +A PV I +
Sbjct: 415 ASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVN 474
Query: 462 TFSRSY 467
F Y
Sbjct: 475 NFGMYY 480
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 217 bits (553), Expect = 2e-56
Identities = 145/486 (29%), Positives = 223/486 (45%), Gaps = 88/486 (18%)
Query: 60 DRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVC-------------- 105
+ R+I+NVGG ++ +TL P TRL L + D L
Sbjct: 5 ENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPP 64
Query: 106 ----------------------------DDYDVTCNEFFFDRNPGAFGTILTFLRAGKLR 137
D+ EFFFDR+PG F +L + R GKL
Sbjct: 65 PRAPPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLH 124
Query: 138 LLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSE 197
++C F+EEL +WGI E ++ CC Y Q + E ++ E D + + D E
Sbjct: 125 CPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQH-RDAEEALDIFETPDLIGGDPGDDE 183
Query: 198 ----------------GPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTA 241
GP GR R R+ + E P+S + A S+ F+ V+
Sbjct: 184 DLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSI 243
Query: 242 VNLSVST------LPSLREEEEQGHCSQMCHNV------FIVESVCVGWFSLEFLLRLIQ 289
+ T + + E G + + + VE VCV WF+ EFL+R++
Sbjct: 244 TTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVF 303
Query: 290 APSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALR 349
+P+K F+++ L +ID VAILP+Y+ + + G ++ K G LRV+R +R
Sbjct: 304 SPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLG---------FLRVVRFVR 354
Query: 350 ILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIEN--------E 401
IL + +L RH +GL+ LG T R T EF LL++FL + + +FA ++Y E
Sbjct: 355 ILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPS 414
Query: 402 MADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFH 461
++ +F +IP +WWAV+TMTT+GYGDM P++ G +V L+G+L +A PV I +
Sbjct: 415 ASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVN 474
Query: 462 TFSRSY 467
F Y
Sbjct: 475 NFGMYY 480
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 216 bits (551), Expect = 3e-56
Identities = 150/471 (31%), Positives = 229/471 (48%), Gaps = 66/471 (14%)
Query: 52 PRQGCQPEDRRR-----RIIINVGGIKYSLPWTTLDEFPLTRLGQL-------KACTNFD 99
P + C E+ + +IIINVGG ++ +TL P TRL L + T+
Sbjct: 20 PSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGG 79
Query: 100 DILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAED 159
+ + C EFFFDR+PG F +L + R GKL ++C F+EEL +WGI E
Sbjct: 80 GVGSSGSSGGGGC-EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDET 138
Query: 160 HLDGCCKRRYLQK--IEEFAEMVEREE--------EDDALDSE--------GRDSEGPAE 201
++ CC Y Q EE ++ E + D+A D E G G
Sbjct: 139 DVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGH 198
Query: 202 GEGRLGRC---MRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQ 258
G G G C R+ + E P+S +V A S+ F+ V+ + T + +
Sbjct: 199 GAGS-GGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNV 257
Query: 259 GHCSQMCHNVFI--------------VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLI 304
++ + + +E VCV WF+LEFL+R++ P F+++ L +I
Sbjct: 258 TEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNII 317
Query: 305 DLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQ 364
D VAILP+Y+ + + G ++ + G LRV+R +RIL + +L RH +GL+
Sbjct: 318 DFVAILPFYLEVGLSGLSSKAARDVLG---------FLRVVRFVRILRIFKLTRHFVGLR 368
Query: 365 TLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMA--------DSPEFTSIPACYW 416
LG T R T EF LL++FL + + +FA ++Y E A D +F +IP +W
Sbjct: 369 VLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFW 428
Query: 417 WAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSY 467
WAV+TMTT+GYGDM P++ G +V L+G+L +A PV I + F Y
Sbjct: 429 WAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 216 bits (551), Expect = 3e-56
Identities = 150/471 (31%), Positives = 229/471 (48%), Gaps = 66/471 (14%)
Query: 52 PRQGCQPEDRRR-----RIIINVGGIKYSLPWTTLDEFPLTRLGQL-------KACTNFD 99
P + C E+ + +IIINVGG ++ +TL P TRL L + T+
Sbjct: 20 PSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGG 79
Query: 100 DILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAED 159
+ + C EFFFDR+PG F +L + R GKL ++C F+EEL +WGI E
Sbjct: 80 GVGSSGSSGGGGC-EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDET 138
Query: 160 HLDGCCKRRYLQK--IEEFAEMVEREE--------EDDALDSE--------GRDSEGPAE 201
++ CC Y Q EE ++ E + D+A D E G G
Sbjct: 139 DVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGH 198
Query: 202 GEGRLGRC---MRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQ 258
G G G C R+ + E P+S +V A S+ F+ V+ + T + +
Sbjct: 199 GAGS-GGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNV 257
Query: 259 GHCSQMCHNVFI--------------VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLI 304
++ + + +E VCV WF+LEFL+R++ P F+++ L +I
Sbjct: 258 TEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNII 317
Query: 305 DLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQ 364
D VAILP+Y+ + + G ++ + G LRV+R +RIL + +L RH +GL+
Sbjct: 318 DFVAILPFYLEVGLSGLSSKAARDVLG---------FLRVVRFVRILRIFKLTRHFVGLR 368
Query: 365 TLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMA--------DSPEFTSIPACYW 416
LG T R T EF LL++FL + + +FA ++Y E A D +F +IP +W
Sbjct: 369 VLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFW 428
Query: 417 WAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSY 467
WAV+TMTT+GYGDM P++ G +V L+G+L +A PV I + F Y
Sbjct: 429 WAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 216 bits (551), Expect = 3e-56
Identities = 150/471 (31%), Positives = 229/471 (48%), Gaps = 66/471 (14%)
Query: 52 PRQGCQPEDRRR-----RIIINVGGIKYSLPWTTLDEFPLTRLGQL-------KACTNFD 99
P + C E+ + +IIINVGG ++ +TL P TRL L + T+
Sbjct: 20 PSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGG 79
Query: 100 DILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAED 159
+ + C EFFFDR+PG F +L + R GKL ++C F+EEL +WGI E
Sbjct: 80 GVGSSGSSGGGGC-EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDET 138
Query: 160 HLDGCCKRRYLQK--IEEFAEMVEREE--------EDDALDSE--------GRDSEGPAE 201
++ CC Y Q EE ++ E + D+A D E G G
Sbjct: 139 DVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGH 198
Query: 202 GEGRLGRC---MRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQ 258
G G G C R+ + E P+S +V A S+ F+ V+ + T + +
Sbjct: 199 GAGS-GGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNV 257
Query: 259 GHCSQMCHNVFI--------------VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLI 304
++ + + +E VCV WF+LEFL+R++ P F+++ L +I
Sbjct: 258 TEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNII 317
Query: 305 DLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQ 364
D VAILP+Y+ + + G ++ + G LRV+R +RIL + +L RH +GL+
Sbjct: 318 DFVAILPFYLEVGLSGLSSKAARDVLG---------FLRVVRFVRILRIFKLTRHFVGLR 368
Query: 365 TLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMA--------DSPEFTSIPACYW 416
LG T R T EF LL++FL + + +FA ++Y E A D +F +IP +W
Sbjct: 369 VLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFW 428
Query: 417 WAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSY 467
WAV+TMTT+GYGDM P++ G +V L+G+L +A PV I + F Y
Sbjct: 429 WAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 214 bits (546), Expect = 1e-55
Identities = 153/477 (32%), Positives = 241/477 (50%), Gaps = 64/477 (13%)
Query: 48 PQDE--PRQGCQPEDRR-RRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNV 104
PQD PRQ + R++IN+ G+++ TL +FP T LG K + D L
Sbjct: 19 PQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLR- 77
Query: 105 CDDYDVTCNEFFFDRNPGAFGTILTFLRAG-KLRLLREMCALSFQEELLYWGIAEDHLDG 163
NE+FFDRN +F IL + ++G +LR + F EE+ ++ + E
Sbjct: 78 --------NEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGE----- 124
Query: 164 CCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSG 223
E +E+ ED+ E E P + R++ + E P S
Sbjct: 125 --------------EAMEKFREDEGFIKE---EERPLPEK----EYQRQVWLLFEYPESS 163
Query: 224 LPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNV-------------FI 270
P +V A +SV+ + ++ V + TLP L+++++ N FI
Sbjct: 164 GPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFI 223
Query: 271 VESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGA 330
VE++C+ WFS E ++R PSK F ++ + ID+VAI+PY+ITL + A + G
Sbjct: 224 VETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGE 283
Query: 331 GNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIAL 390
+ L +LRV+R +R+ + +L+RHS GLQ LG T + RE GLL+ FL + + L
Sbjct: 284 QATSL----AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVIL 339
Query: 391 FAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGIL 450
F+ +Y E E A+S F+SIP +WWAV++MTTVGYGDM P + G++V ++G+L
Sbjct: 340 FSSAVYFAEAEEAES-HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVL 398
Query: 451 LMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSASS 507
+A PV I F+ Y + +E +AQ L S +++ DSD+ S+S+
Sbjct: 399 TIALPVPVIVSNFNYFYHRETEGEE-----QAQLL--HVSSPNLASDSDLSRRSSST 448
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 211 bits (537), Expect = 1e-54
Identities = 151/462 (32%), Positives = 223/462 (48%), Gaps = 77/462 (16%)
Query: 46 LRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVC 105
+ P+ P GC R+++NV G+++ TL FP T LG F
Sbjct: 1 MEPRCPPPCGCC-----ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRF------- 48
Query: 106 DDYDVTCNEFFFDRNPGAFGTILTFLRA-GKLRLLREMCALSFQEELLYWGIAEDHLDGC 164
YD E+FFDR+ +F +L + ++ G+LR + F EE+ ++G+
Sbjct: 49 --YDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLG------- 99
Query: 165 CKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGR--CMRRLRDMVERPHS 222
A + R ED+ P E L R R+L + E P S
Sbjct: 100 ------------AAALARLREDEGC---------PVPPERPLPRRAFARQLWLLFEFPES 138
Query: 223 GLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEE----------------QGHCSQMCH 266
+V A +SVL + V+ V + TLP R++ + SQM
Sbjct: 139 SQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPG 198
Query: 267 N---------VFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLL 317
N F+VE++C+ WFS E L+RL+ PSK F ++ + LID VAILPY++ L
Sbjct: 199 NPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALG 258
Query: 318 VDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREF 377
+ A R+ G G + +LRV+R +R+ + +L+RHS GLQ LG T R RE
Sbjct: 259 TELA----RQRGVGQQAMSLA--ILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMREL 312
Query: 378 GLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPG 437
GLL+ FL + + LF+ +Y E + DS FTSIP +WWAV+TMTTVGYGDM P + G
Sbjct: 313 GLLIFFLFIGVVLFSSAVYFAEVDRVDS-HFTSIPESFWWAVVTMTTVGYGDMAPVTVGG 371
Query: 438 QVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMF 479
++V ++G+L ++ PV I FS Y + +E MF
Sbjct: 372 KIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMF 413
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,388,148
Number of Sequences: 37866
Number of extensions: 879609
Number of successful extensions: 4009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 78
Number of HSP's that attempted gapping in prelim test: 3556
Number of HSP's gapped (non-prelim): 371
length of query: 513
length of database: 18,247,518
effective HSP length: 107
effective length of query: 406
effective length of database: 14,195,856
effective search space: 5763517536
effective search space used: 5763517536
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.