Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 27436984
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
(655 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 1318 0.0
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 1271 0.0
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 959 0.0
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 803 0.0
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 279 7e-75
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 270 3e-72
gi|25952092 potassium voltage-gated channel, shaker-related subf... 268 2e-71
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 266 6e-71
gi|119395748 potassium voltage-gated channel subfamily A member ... 265 1e-70
gi|88758565 potassium voltage-gated channel, shaker-related subf... 263 3e-70
gi|5031819 potassium voltage-gated channel, shaker-related subfa... 259 4e-69
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 259 7e-69
gi|163792201 Shaw-related voltage-gated potassium channel protei... 259 7e-69
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 258 9e-69
gi|25952087 potassium voltage-gated channel, shaker-related subf... 256 6e-68
gi|88758576 Shaw-related voltage-gated potassium channel protein... 250 3e-66
gi|24497462 Shaw-related voltage-gated potassium channel protein... 250 3e-66
gi|24497464 Shaw-related voltage-gated potassium channel protein... 250 3e-66
gi|21217563 Shaw-related voltage-gated potassium channel protein... 249 6e-66
gi|24497460 Shaw-related voltage-gated potassium channel protein... 248 2e-65
gi|21217561 Shaw-related voltage-gated potassium channel protein... 247 2e-65
gi|24497458 Shaw-related voltage-gated potassium channel protein... 246 5e-65
gi|4504821 potassium voltage-gated channel, shaker-related subfa... 245 8e-65
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 236 6e-62
gi|20070166 potassium voltage-gated channel, subfamily F, member... 231 2e-60
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 226 7e-59
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 224 3e-58
gi|27436988 potassium voltage-gated channel, subfamily G, member... 222 7e-58
gi|6912444 potassium voltage-gated channel, subfamily G, member ... 211 1e-54
gi|27436996 potassium voltage-gated channel, subfamily G, member... 207 2e-53
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 1318 bits (3411), Expect = 0.0
Identities = 655/655 (100%), Positives = 655/655 (100%)
Query: 1 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER 60
MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
Sbjct: 1 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER 60
Query: 61 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF 120
YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
Sbjct: 61 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF 120
Query: 121 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST 180
YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
Sbjct: 121 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST 180
Query: 181 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE 240
LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
Sbjct: 181 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE 240
Query: 241 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF 300
YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
Sbjct: 241 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF 300
Query: 301 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY 360
SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
Sbjct: 301 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY 360
Query: 361 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
Sbjct: 361 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
Query: 421 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL 480
AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
Sbjct: 421 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL 480
Query: 481 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP 540
HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
Sbjct: 481 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP 540
Query: 541 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG 600
GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
Sbjct: 541 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG 600
Query: 601 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL 655
LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
Sbjct: 601 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL 655
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 1271 bits (3289), Expect = 0.0
Identities = 636/655 (97%), Positives = 636/655 (97%), Gaps = 19/655 (2%)
Query: 1 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER 60
MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
Sbjct: 1 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER 60
Query: 61 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF 120
YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
Sbjct: 61 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF 120
Query: 121 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST 180
YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
Sbjct: 121 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST 180
Query: 181 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE 240
LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
Sbjct: 181 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE 240
Query: 241 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF 300
YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
Sbjct: 241 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF 300
Query: 301 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY 360
SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
Sbjct: 301 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY 360
Query: 361 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
Sbjct: 361 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
Query: 421 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL 480
AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
Sbjct: 421 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL 480
Query: 481 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP 540
HCLEKTT NHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
Sbjct: 481 HCLEKTT-------------------NHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP 521
Query: 541 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG 600
GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
Sbjct: 522 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG 581
Query: 601 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL 655
LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
Sbjct: 582 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL 636
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 959 bits (2478), Expect = 0.0
Identities = 487/660 (73%), Positives = 556/660 (84%), Gaps = 35/660 (5%)
Query: 1 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR-QDELIVLNVSGRRFQTWRTTLE 59
MAAGVAAWLPFARAAAIGWMPVA+ PMP P + KR QD LIVLNVSG RFQTW+ TLE
Sbjct: 1 MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE 60
Query: 60 RYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELA 119
RYPDTLLGS+E++FF++ +T++YFFDRDP++FR +LNFYRTGKLHYPR+ECISAYD+ELA
Sbjct: 61 RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA 120
Query: 120 FYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQES-MPSLSFRQTMWRAFENPHT 178
F+G++PEIIGDCCYEEYKDR+RENAERL DD D++ ES +P+++ RQ +WRAFENPHT
Sbjct: 121 FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT 180
Query: 179 STLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS-KELPCGERYSVAFFCLDTACVMIF 237
ST+ALVFYYVTGFFIAVSVI NVVETVPCG+ PG KELPCGERY+VAFFCLDTACVMIF
Sbjct: 181 STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF 240
Query: 238 TVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRI 297
TVEYLLRL AAPSRYRF+RSVMSIIDVVAI+PYYIGLVMT+NEDVSGAFVTLRVFRVFRI
Sbjct: 241 TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI 300
Query: 298 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS 357
FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPA+
Sbjct: 301 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA 360
Query: 358 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD 417
FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
Sbjct: 361 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD 420
Query: 418 KRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHH 477
KRRAQKKARLARIR AK+GS+NAY+ SKRNGLL+ L+ + E+ + K+ S E+QHH
Sbjct: 421 KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQ-SSEDEQAFVSKSGSSFETQHH 479
Query: 478 HLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLS 537
HLLHCLEKTT NHEF+DEQ+FE++CME + N PS+ SPSLS
Sbjct: 480 HLLHCLEKTT-------------------NHEFVDEQVFEESCMEVATVNRPSSHSPSLS 520
Query: 538 SHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKA 597
S G+T+TCCSRR KKT +PN+N+ + S+QELSTI I+ E+ L+ SRSSLN K
Sbjct: 521 SQQGVTSTCCSRRHKKTFRIPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKM 580
Query: 598 DDGLRPNCKTSQITTAIISIPTPPALTPEGESRP--PPASPGPNTNIPSIASNVVKVSAL 655
++ ++ NC+ +TTAIISIPTPP TPEG+ RP P S G N+V+VSAL
Sbjct: 581 EECVKLNCEQPYVTTAIISIPTPPVTTPEGDDRPESPEYSGG----------NIVRVSAL 630
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 803 bits (2075), Expect = 0.0
Identities = 430/678 (63%), Positives = 510/678 (75%), Gaps = 54/678 (7%)
Query: 1 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER 60
MAAG+A WLPFARAAA+GW+P+A P+P AP K R DE++V+NVSGRRF+TW+ TL+R
Sbjct: 1 MAAGLATWLPFARAAAVGWLPLAQQPLPPAPGVKASRGDEVLVVNVSGRRFETWKNTLDR 60
Query: 61 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF 120
YPDTLLGS+EKEFF++ D+ EYFFDRDP++FR VLNFYRTG+LH PR ECI A+D+ELAF
Sbjct: 61 YPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAF 120
Query: 121 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSL----SFRQTMWRAFENP 176
YG++PE++GDCC EEY+DRK+ENAERL +D ++E + P+L S RQ +WRAFENP
Sbjct: 121 YGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDG-PALPAGSSLRQRLWRAFENP 179
Query: 177 HTSTLALVFYYVTGFFIAVSVITNVVETVPC--GTVPGSKELPCGERYSVAFFCLDTACV 234
HTST ALVFYYVTGFFIAVSVI NVVET+PC S+E PCGER+ AFFC+DTACV
Sbjct: 180 HTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACV 239
Query: 235 MIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRV 294
+IFT EYLLRLFAAPSR RF+RSVMS+IDVVAI+PYYIGL++ N+DVSGAFVTLRVFRV
Sbjct: 240 LIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVTLRVFRV 299
Query: 295 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSI 354
FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKG++ + FTSI
Sbjct: 300 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSI 359
Query: 355 PASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ 414
PA+FWYTIVTMTTLGYGDMVP TIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ
Sbjct: 360 PAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ 419
Query: 415 RADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHM-GKTTSLIE 473
RADKRRAQ+K RLARIR+AK+G++NA+L K+NG LE +G+ EE+ + + S E
Sbjct: 420 RADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNG----GLEDSGSGEEQALCVRNRSAFE 475
Query: 474 SQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRS 533
QHHHLLHCLEKTT HEF DE F + + + ++RS
Sbjct: 476 QQHHHLLHCLEKTT-------------------CHEFTDELTFSE-ALGAVSPGGRTSRS 515
Query: 534 PSLSSHP----GLTTTCCSRRSK-KTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTT 588
S+SS P L ++CC RR+K + L NS +R SMQEL + G +
Sbjct: 516 TSVSSQPVGPGSLLSSCCPRRAKRRAIRLANSTASVSR-GSMQELDM--LAGLRRSHAPQ 572
Query: 589 SRSSLNLKADDGLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPG----------- 637
SRSSLN K D L NC + AIISIPTPPA TP+ ES+ P+SPG
Sbjct: 573 SRSSLNAKPHDSLDLNCDSRDFVAAIISIPTPPANTPD-ESQ--PSSPGGGGRAGSTLRN 629
Query: 638 PNTNIPSIASNVVKVSAL 655
+ P + VK+S+L
Sbjct: 630 SSLGTPCLFPETVKISSL 647
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 279 bits (713), Expect = 7e-75
Identities = 154/432 (35%), Positives = 243/432 (56%), Gaps = 45/432 (10%)
Query: 27 MPLAPAD--KNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLG-----STEKEFF----- 74
+P P D ++K + +NV G + TL+R P T LG +T +
Sbjct: 20 LPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDD 79
Query: 75 FNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYE 134
+N + EYFFDR P F +LNFYRTGKLH C ++ EL ++GI + CC
Sbjct: 80 YNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQA 139
Query: 135 EYKDRK-------RENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYY 187
Y +K R AE + + E + P R+ +W E P++S A +
Sbjct: 140 RYHQKKEQMNEELRREAETMREREGEEFDNTCCPDK--RKKLWDLLEKPNSSVAAKILAI 197
Query: 188 VTGFFIAVSVITNVVETVP-------CGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE 240
V+ FI +S I + T+P G + +++L ++ C+ FT+E
Sbjct: 198 VSILFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAH----------VEAVCIAWFTME 247
Query: 241 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNN-------EDVSGAFVTLRVFR 293
YLLR ++P++++F + +++ID++AI+PYY+ + +T + ++V R+ R
Sbjct: 248 YLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMR 307
Query: 294 VFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTS 353
+ RI K +RHS GL+ LG+TL+ +ELG L+ L M I+IF++++F+AEK A+KFTS
Sbjct: 308 ILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDATKFTS 367
Query: 354 IPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQN 413
IPASFW+ +TMTT+GYGD+ PKT+ GKI G +C ++GVLVIALP+P+IV+NFS Y +
Sbjct: 368 IPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQ 427
Query: 414 QRADKRRAQKKA 425
+R +K +++A
Sbjct: 428 KRQEKAIKRREA 439
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 270 bits (690), Expect = 3e-72
Identities = 159/473 (33%), Positives = 251/473 (53%), Gaps = 41/473 (8%)
Query: 34 KNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLG-----STEKEFF-----FNEDTKEYF 83
++K + LNV G + TL+R P T LG +T ++ D EYF
Sbjct: 25 RSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYF 84
Query: 84 FDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
FDR P F +LNFYRTG+LH C ++ EL ++GI + CC Y +K +
Sbjct: 85 FDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQM 144
Query: 144 AERLMDDNDSENNQESMP-----SLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVI 198
E L + ++ +E R+ +W E P++S A + ++ FI +S I
Sbjct: 145 NEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLSTI 204
Query: 199 TNVVETVPCGTVPGSKELPCGERYSVA-----FFCLDTACVMIFTVEYLLRLFAAPSRYR 253
+ T+P EL + + + ++ C+ FT+EYLLR ++P +++
Sbjct: 205 ALSLNTLP--------ELQSLDEFGQSTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWK 256
Query: 254 FIRSVMSIIDVVAIMPYYIGLVMTNN-------EDVSGAFVTLRVFRVFRIFKFSRHSQG 306
F + ++ ID++AI+PYY+ + +T + ++V R+ R+ RI K +RHS G
Sbjct: 257 FFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTG 316
Query: 307 LRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMT 366
L+ LG+TL+ +ELG L+ L M I+IF++++F+AEK +KF SIPASFW+ +TMT
Sbjct: 317 LQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMT 376
Query: 367 TLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKAR 426
T+GYGD+ PKT+ GKI G +C ++GVLVIALP+P+IV+NFS Y + +R +K K R
Sbjct: 377 TVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEK---AIKRR 433
Query: 427 LARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHL 479
A R + GS + E +++ E+MGK + Q +HL
Sbjct: 434 EALERAKRNGSIVSMNMKDAFARSIEMMDIVVEKNGENMGKKDKV---QDNHL 483
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 268 bits (684), Expect = 2e-71
Identities = 159/412 (38%), Positives = 236/412 (57%), Gaps = 48/412 (11%)
Query: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTK-EYFFDRDPEVFRCVLNFY 98
E +VLNV+G RF+T TL R+PDTLLG + F +D + EYFFDR F VL +Y
Sbjct: 13 ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYY 72
Query: 99 RTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQ 157
++G +L P + + + +E+AFYG+ + R RE D+ +
Sbjct: 73 QSGGRLRRPAHVPLDVFLEEVAFYGLGAAALA---------RLRE------DEGCPVPPE 117
Query: 158 ESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP----------- 206
+P +F + +W FE P +S A V V+ I VS++ +ET+P
Sbjct: 118 RPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGL 177
Query: 207 -----CGTVP----GSKELPCGER---YSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRF 254
G P GS ++P ++ FF ++T C+ F+ E L+RL PS+ F
Sbjct: 178 AAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIF 237
Query: 255 IRSVMSIIDVVAIMPYYI--GLVMTNNEDVSGAFVTL------RVFRVFRIFKFSRHSQG 306
++VM++ID VAI+PY++ G + V ++L R+ RVFRIFK SRHS+G
Sbjct: 238 FKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKG 297
Query: 307 LRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMT 366
L+ILG TL++ ELG L+F L + +++F++ +++AE S FTSIP SFW+ +VTMT
Sbjct: 298 LQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMT 357
Query: 367 TLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADK 418
T+GYGDM P T+ GKI GS+C+++GVL I+LPVPVIVSNFS YH+ ++
Sbjct: 358 TVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 266 bits (679), Expect = 6e-71
Identities = 151/409 (36%), Positives = 240/409 (58%), Gaps = 44/409 (10%)
Query: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFFDRDPEVFRCVLNFY 98
E +V+N+SG RF+T TL ++P+TLLG +K +F+ EYFFDR+ F +L +Y
Sbjct: 33 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYY 92
Query: 99 RT-GKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQ 157
++ G+L P + + +E+ FY +G+ E +++ D+ + +
Sbjct: 93 QSGGRLRRPVNVPLDIFSEEIRFYE-----LGEEAMEMFRE----------DEGYIKEEE 137
Query: 158 ESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPC---------- 207
+P F++ +W FE P +S A + V+ I +S+++ +ET+P
Sbjct: 138 RPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHG 197
Query: 208 --GTVPGSKELPCGERYSVA----FFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSI 261
T G + S + FF ++T C++ F+ E+L+R FA PS+ F ++M+I
Sbjct: 198 SGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNI 257
Query: 262 IDVVAIMPYYIGL----------VMTNNEDVSGAFV-TLRVFRVFRIFKFSRHSQGLRIL 310
ID+VAI+PY+I L + +S A + +R+ RVFRIFK SRHS+GL+IL
Sbjct: 258 IDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQIL 317
Query: 311 GYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGY 370
G TLK+ ELG L+F L + +I+F++ +++AE S+F SIP +FW+ +V+MTT+GY
Sbjct: 318 GQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGY 377
Query: 371 GDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 419
GDMVP TI GKI GS+C+++GVL IALPVPVIVSNF+ YH+ +++
Sbjct: 378 GDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ 426
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 265 bits (677), Expect = 1e-70
Identities = 148/403 (36%), Positives = 241/403 (59%), Gaps = 38/403 (9%)
Query: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFFDRDPEVFRCVLNFY 98
E +V+N+SG RF+T TL ++P+TLLG+ +K +F+ EYFFDR+ F +L +Y
Sbjct: 37 ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYY 96
Query: 99 RTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQ 157
++G +L P + + +E+ FY + G+ E++++ D+ + +
Sbjct: 97 QSGGRLRRPVNVPLDMFSEEIKFYEL-----GEEAMEKFRE----------DEGFIKEEE 141
Query: 158 ESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP--------CGT 209
+P +++ +W FE P +S A V V+ I +S++ +ET+P GT
Sbjct: 142 RPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGT 201
Query: 210 V---PGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVA 266
V + + ++ FF ++T C++ F+ E ++R FA PS+ F +++M+ ID+VA
Sbjct: 202 VHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVA 261
Query: 267 IMPYYIGL---VMTNNEDVSGAFVT-------LRVFRVFRIFKFSRHSQGLRILGYTLKS 316
I+PY+I L + + G T +R+ RVFRIFK SRHS+GL+ILG TLK+
Sbjct: 262 IIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKA 321
Query: 317 CASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPK 376
ELG L+F L + +I+F++ +++AE + S F+SIP +FW+ +V+MTT+GYGDM P
Sbjct: 322 SMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPV 381
Query: 377 TIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 419
TI GKI GS+C+++GVL IALPVPVIVSNF+ YH+ +++
Sbjct: 382 TIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ 424
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 263 bits (673), Expect = 3e-70
Identities = 162/473 (34%), Positives = 256/473 (54%), Gaps = 58/473 (12%)
Query: 26 PMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFF 84
P L A + E +V+N+SG RF+T TL ++P+TLLG ++ +F+ EYFF
Sbjct: 90 PPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFF 149
Query: 85 DRDPEVFRCVLNFYRTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
DR+ F +L +Y++G ++ P I + +E+ FY + G+ E++++
Sbjct: 150 DRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL-----GEEAMEKFRE----- 199
Query: 144 AERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVE 203
D+ + +P F++ +W FE P +S A V+ I +S++ +E
Sbjct: 200 -----DEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLE 254
Query: 204 TVPCGTVPGSKELPC---------------GER-----YSVAFFCLDTACVMIFTVEYLL 243
T+P K+ P G R +S FF ++T C++ F+ E L+
Sbjct: 255 TLP--EFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLV 312
Query: 244 RLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMT------NNEDVSGAFV--TLRVFRVF 295
R FA PS+ F R++M++ID+VAI+PY+I L N + + +R+ RVF
Sbjct: 313 RFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVF 372
Query: 296 RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIP 355
RIFK SRHS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE S F+SIP
Sbjct: 373 RIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIP 432
Query: 356 ASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQR 415
+FW+ +VTMTT+GYGDM P TI GKI GS+C+++GVL IALPVPVIVSNF+ YH+
Sbjct: 433 DAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETE 492
Query: 416 ADKRR-----------AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELT 457
+++ + L + R T S + Y+ + G+ + A T
Sbjct: 493 GEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQT 545
>gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
Length = 511
Score = 259 bits (663), Expect = 4e-69
Identities = 149/418 (35%), Positives = 243/418 (58%), Gaps = 42/418 (10%)
Query: 26 PMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFF 84
P P+ + N+R +++N++G RF+T TL ++P+TLLG EK FF+ EYFF
Sbjct: 76 PEPVVLNEGNQR----VIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFF 131
Query: 85 DRDPEVFRCVLNFYRTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
DR+ F +L +Y++G K+ P I + DE++FY + E + D+ RE
Sbjct: 132 DRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSEAM---------DQFRE- 181
Query: 144 AERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVE 203
D+ ++ + +P+ + W FE P +S+ A V+ + +S+ +E
Sbjct: 182 -----DEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLE 236
Query: 204 TVP------------CGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSR 251
T+P + SK + ++ FF +++ C++ FT E +LR PS+
Sbjct: 237 TLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSK 296
Query: 252 YRFIRSVMSIIDVVAIMPYYIGLVM--------TNNEDVSGAFVTL-RVFRVFRIFKFSR 302
F R++M+IID+++I+PY+ L+ + +++S A + + R+ RVFRIFK SR
Sbjct: 297 TDFFRNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSR 356
Query: 303 HSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTI 362
HS+GL+ILG TLK+ ELG L+F L + +I+F++ +++AE S F+SIP FW+ +
Sbjct: 357 HSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAV 416
Query: 363 VTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
VTMTT+GYGDM P T GKI G++C+++GVL IALPVPVIVSNF+ YH+ ++++
Sbjct: 417 VTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQ 474
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 259 bits (661), Expect = 7e-69
Identities = 160/459 (34%), Positives = 240/459 (52%), Gaps = 69/459 (15%)
Query: 38 QDELIVLNVSGRRFQTWRTTLERYPDTLLG-----STEKEFFFNEDTKEYFFDRDPEVFR 92
+ E IV+NV G R QT+R+TL P T L F ++ E+FFDR P VF
Sbjct: 6 ESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFA 65
Query: 93 CVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMD--- 149
+LN+YRTGKLH P C Y++ELAF+GI + CC+ Y R+ +AE +D
Sbjct: 66 HILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTY--RQHRDAEEALDSFG 123
Query: 150 ----DNDSENNQESMPSLS-----------------------------FRQTMWRAFENP 176
DN +++ P S ++ +W FE+P
Sbjct: 124 GAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDP 183
Query: 177 HTSTLALVFYYVTGFFIAVSVITNVVETVPC-----------GTVPGSKELPCGERYSVA 225
++S A + + FFI VS+ T +ET G++ E + A
Sbjct: 184 YSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEA 243
Query: 226 FFC-LDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYI-----GLVMTNN 279
F ++ CV+ FT E+L+R+ P++ FI++ ++IID VAI+P+Y+ GL
Sbjct: 244 FLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAA 303
Query: 280 EDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVM 339
+DV G +R R+ RIFK +RH GLR+LG+TL++ +E L+ L + ++IFAT++
Sbjct: 304 KDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMI 363
Query: 340 FYAEK---------GSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLS 390
+YAE+ S + F +IP FW+ +VTMTTLGYGDM P+T +G + G++C+L+
Sbjct: 364 YYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 423
Query: 391 GVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLAR 429
GVL IA+PVPVIV+NF Y K +KK + R
Sbjct: 424 GVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPR 462
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 259 bits (661), Expect = 7e-69
Identities = 160/459 (34%), Positives = 240/459 (52%), Gaps = 69/459 (15%)
Query: 38 QDELIVLNVSGRRFQTWRTTLERYPDTLLG-----STEKEFFFNEDTKEYFFDRDPEVFR 92
+ E IV+NV G R QT+R+TL P T L F ++ E+FFDR P VF
Sbjct: 6 ESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFA 65
Query: 93 CVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMD--- 149
+LN+YRTGKLH P C Y++ELAF+GI + CC+ Y R+ +AE +D
Sbjct: 66 HILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTY--RQHRDAEEALDSFG 123
Query: 150 ----DNDSENNQESMPSLS-----------------------------FRQTMWRAFENP 176
DN +++ P S ++ +W FE+P
Sbjct: 124 GAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDP 183
Query: 177 HTSTLALVFYYVTGFFIAVSVITNVVETVPC-----------GTVPGSKELPCGERYSVA 225
++S A + + FFI VS+ T +ET G++ E + A
Sbjct: 184 YSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEA 243
Query: 226 FFC-LDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYI-----GLVMTNN 279
F ++ CV+ FT E+L+R+ P++ FI++ ++IID VAI+P+Y+ GL
Sbjct: 244 FLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAA 303
Query: 280 EDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVM 339
+DV G +R R+ RIFK +RH GLR+LG+TL++ +E L+ L + ++IFAT++
Sbjct: 304 KDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMI 363
Query: 340 FYAEK---------GSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLS 390
+YAE+ S + F +IP FW+ +VTMTTLGYGDM P+T +G + G++C+L+
Sbjct: 364 YYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 423
Query: 391 GVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLAR 429
GVL IA+PVPVIV+NF Y K +KK + R
Sbjct: 424 GVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPR 462
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 258 bits (660), Expect = 9e-69
Identities = 152/415 (36%), Positives = 237/415 (57%), Gaps = 49/415 (11%)
Query: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFFDRDPEVFRCVLNFY 98
E +V+NVSG RF+T TL ++P+TLLG EK +F+ EYFFDR+ F +L +Y
Sbjct: 176 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY 235
Query: 99 RTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQ 157
++G +L P + +E+ FY + E + K R+ E R E
Sbjct: 236 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEAL-------LKFREDEGFVR-------EEED 281
Query: 158 ESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP----------- 206
++P F++ +W FE P +S+ A V+ I +S++ +ET+P
Sbjct: 282 RALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMA 341
Query: 207 -----CGTVPGSKELPCGER-----YSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRFIR 256
G + P E ++ FF ++T C++ F+ E+++R FA PS+ F +
Sbjct: 342 LSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFK 401
Query: 257 SVMSIIDVVAIMPYYIGLVMTNNEDVSG---------AFVTLRVFR---VFRIFKFSRHS 304
++M+IID+V+I+PY+I L + G +F LR+ R VFRIFK SRHS
Sbjct: 402 NIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHS 461
Query: 305 QGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVT 364
+GL+ILG+TL++ ELG L+F L + +I+F++ +++AE + F SIP +FW+ +VT
Sbjct: 462 KGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVT 521
Query: 365 MTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 419
MTT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+ +++
Sbjct: 522 MTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQ 576
>gi|25952087 potassium voltage-gated channel, shaker-related
subfamily, member 5 [Homo sapiens]
Length = 613
Score = 256 bits (653), Expect = 6e-68
Identities = 155/417 (37%), Positives = 230/417 (55%), Gaps = 63/417 (15%)
Query: 44 LNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFFDRDPEVFRCVLNFYRTG- 101
+N+SG RF+T TL ++P+TLLG K +F+ EYFFDR+ F +L +Y++G
Sbjct: 124 INISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGG 183
Query: 102 KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMP 161
+L P + + DE+ FY + GD E +++ D+ + ++ +P
Sbjct: 184 RLRRPVNVSLDVFADEIRFYQL-----GDEAMERFRE----------DEGFIKEEEKPLP 228
Query: 162 SLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP--------------- 206
F++ +W FE P +S A V+ I +S+IT +ET+P
Sbjct: 229 RNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAP 288
Query: 207 ---CGTVPGSKEL-----PCGERYSVA--------FFCLDTACVMIFTVEYLLRLFAAPS 250
PG+ P G + FF ++T CV+ FT E L+R FA PS
Sbjct: 289 HQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPS 348
Query: 251 RYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGA---------------FVTLRVFRVF 295
+ F R++M+IIDVVAI PY+I L E G +R+ RVF
Sbjct: 349 KAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVF 408
Query: 296 RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIP 355
RIFK SRHS+GL+ILG TL++ ELG L+F L + +I+F++ +++AE + + F+SIP
Sbjct: 409 RIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIP 468
Query: 356 ASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQ 412
+FW+ +VTMTT+GYGDM P T+ GKI GS+C+++GVL IALPVPVIVSNF+ YH+
Sbjct: 469 DAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHR 525
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 250 bits (639), Expect = 3e-66
Identities = 160/469 (34%), Positives = 241/469 (51%), Gaps = 80/469 (17%)
Query: 40 ELIVLNVSGRRFQTWRTTLERYPDTLL----------------GSTEKEFFFNEDTKEYF 83
E I++NV G R +T+R+TL P T L G E+F
Sbjct: 36 EKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFF 95
Query: 84 FDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
FDR P VF VLN+YRTGKLH P C +++EL F+GI + CC+ Y R+ +
Sbjct: 96 FDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTY--RQHRD 153
Query: 144 AERLMD-------------DNDSENNQESMPSLS--------------------FRQTMW 170
AE +D +D + E +L ++ MW
Sbjct: 154 AEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMW 213
Query: 171 RAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS--KELPCGERYSVAF-- 226
FE+P++S A V + + FFI VS+ T +ET + + + L G SV F
Sbjct: 214 ALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRR 273
Query: 227 --------FCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYI-----G 273
++ CV+ FT+E+L+R+ P F++++++IID VAI+P+Y+ G
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSG 333
Query: 274 LVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAII 333
L DV G +R R+ RIFK +RH GLR+LG+TL++ +E L+ L + ++
Sbjct: 334 LSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVL 393
Query: 334 IFATVMFYAEK---------GSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFG 384
IFAT+++YAE+ G+ + F +IP FW+ +VTMTTLGYGDM PKT +G + G
Sbjct: 394 IFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVG 453
Query: 385 SICSLSGVLVIALPVPVIVSNFSRIYH---QNQRADKRRAQKKARLARI 430
++C+L+GVL IA+PVPVIV+NF Y Q+ K+R + R A++
Sbjct: 454 ALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQL 502
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 250 bits (639), Expect = 3e-66
Identities = 160/469 (34%), Positives = 241/469 (51%), Gaps = 80/469 (17%)
Query: 40 ELIVLNVSGRRFQTWRTTLERYPDTLL----------------GSTEKEFFFNEDTKEYF 83
E I++NV G R +T+R+TL P T L G E+F
Sbjct: 36 EKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFF 95
Query: 84 FDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
FDR P VF VLN+YRTGKLH P C +++EL F+GI + CC+ Y R+ +
Sbjct: 96 FDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTY--RQHRD 153
Query: 144 AERLMD-------------DNDSENNQESMPSLS--------------------FRQTMW 170
AE +D +D + E +L ++ MW
Sbjct: 154 AEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMW 213
Query: 171 RAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS--KELPCGERYSVAF-- 226
FE+P++S A V + + FFI VS+ T +ET + + + L G SV F
Sbjct: 214 ALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRR 273
Query: 227 --------FCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYI-----G 273
++ CV+ FT+E+L+R+ P F++++++IID VAI+P+Y+ G
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSG 333
Query: 274 LVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAII 333
L DV G +R R+ RIFK +RH GLR+LG+TL++ +E L+ L + ++
Sbjct: 334 LSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVL 393
Query: 334 IFATVMFYAEK---------GSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFG 384
IFAT+++YAE+ G+ + F +IP FW+ +VTMTTLGYGDM PKT +G + G
Sbjct: 394 IFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVG 453
Query: 385 SICSLSGVLVIALPVPVIVSNFSRIYH---QNQRADKRRAQKKARLARI 430
++C+L+GVL IA+PVPVIV+NF Y Q+ K+R + R A++
Sbjct: 454 ALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQL 502
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 250 bits (639), Expect = 3e-66
Identities = 160/469 (34%), Positives = 241/469 (51%), Gaps = 80/469 (17%)
Query: 40 ELIVLNVSGRRFQTWRTTLERYPDTLL----------------GSTEKEFFFNEDTKEYF 83
E I++NV G R +T+R+TL P T L G E+F
Sbjct: 36 EKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFF 95
Query: 84 FDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKREN 143
FDR P VF VLN+YRTGKLH P C +++EL F+GI + CC+ Y R+ +
Sbjct: 96 FDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTY--RQHRD 153
Query: 144 AERLMD-------------DNDSENNQESMPSLS--------------------FRQTMW 170
AE +D +D + E +L ++ MW
Sbjct: 154 AEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMW 213
Query: 171 RAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS--KELPCGERYSVAF-- 226
FE+P++S A V + + FFI VS+ T +ET + + + L G SV F
Sbjct: 214 ALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRR 273
Query: 227 --------FCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYI-----G 273
++ CV+ FT+E+L+R+ P F++++++IID VAI+P+Y+ G
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSG 333
Query: 274 LVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAII 333
L DV G +R R+ RIFK +RH GLR+LG+TL++ +E L+ L + ++
Sbjct: 334 LSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVL 393
Query: 334 IFATVMFYAEK---------GSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFG 384
IFAT+++YAE+ G+ + F +IP FW+ +VTMTTLGYGDM PKT +G + G
Sbjct: 394 IFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVG 453
Query: 385 SICSLSGVLVIALPVPVIVSNFSRIYH---QNQRADKRRAQKKARLARI 430
++C+L+GVL IA+PVPVIV+NF Y Q+ K+R + R A++
Sbjct: 454 ALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQL 502
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 249 bits (636), Expect = 6e-66
Identities = 176/548 (32%), Positives = 276/548 (50%), Gaps = 73/548 (13%)
Query: 80 KEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDR 139
+E+FFDR P VF VLN+YRTGKLH P C +++ELAF+GI + CC+ Y R
Sbjct: 100 REFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTY--R 157
Query: 140 KRENAERLMD--------------DNDSENNQESMPSLS--------------FRQTMWR 171
+ +AE +D D D + + + + MW
Sbjct: 158 QHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWA 217
Query: 172 AFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSV------- 224
FE+P++S A + + FFI VS+ T +ET + +K P SV
Sbjct: 218 LFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIE 277
Query: 225 ---AFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYI-----GLVM 276
A ++ CV+ FT E+L+R+ +P++ FI+++++IID VAI+P+Y+ GL
Sbjct: 278 TDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSS 337
Query: 277 TNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFA 336
+DV G +R R+ RIFK +RH GLR+LG+TL++ +E L+ L + ++IFA
Sbjct: 338 KAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFA 397
Query: 337 TVMFYAEK---------GSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSIC 387
T+++YAE+ S ++F +IP FW+ +VTMTTLGYGDM P+T +G + G++C
Sbjct: 398 TMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALC 457
Query: 388 SLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRN 447
+L+GVL IA+PVPVIV+NF +Y+ A ++ +K+ + I A SS + ++ N
Sbjct: 458 ALAGVLTIAMPVPVIVNNFG-MYYSLAMAKQKLPRKRKK--HIPPAPQASSPTFCKTELN 514
Query: 448 GLLNEALELTGTPEEEHMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDP-LLSVRTSTIK 506
N T + +GK L+E H+ + + +TG + P L +R S+ +
Sbjct: 515 MACN------STQSDTCLGKDNRLLE--HNRSVLSGDDSTGSEPPLSPPERLPIRRSSTR 566
Query: 507 NHEFIDEQMF-----EQNCMESSMQNYPSTRSPSLSSHPGLTTTCCSRRSKKTTHLPNSN 561
+ E F + C +S SL++ GL + R T NS
Sbjct: 567 DKNRRGETCFLLTTGDYTCASDGGIRKGYEKSRSLNNIAGLAGN--ALRLSPVTSPYNSP 624
Query: 562 LPATRLRS 569
P R RS
Sbjct: 625 CPLRRSRS 632
Score = 32.0 bits (71), Expect = 1.8
Identities = 16/35 (45%), Positives = 24/35 (68%), Gaps = 3/35 (8%)
Query: 39 DELIVLNVSGRRFQTWRTTLERYPDT---LLGSTE 70
+E ++LNV G R +T+R+TL+ P T LL S+E
Sbjct: 7 NERVILNVGGTRHETYRSTLKTLPGTRLALLASSE 41
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 248 bits (632), Expect = 2e-65
Identities = 160/476 (33%), Positives = 242/476 (50%), Gaps = 88/476 (18%)
Query: 42 IVLNVSGRRFQTWRTTLERYPDT-LLGSTEKE----FFFNEDTKEYFFDRDPEVFRCVLN 96
IV+NV G R +T+R+TL P T L G TE E F ++ E+FFDR P VF VLN
Sbjct: 90 IVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLN 149
Query: 97 FYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCC---YEEYKDRKRE----------- 142
+YRTGKLH P C +++EL F+GI + CC Y +++D +
Sbjct: 150 YYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAG 209
Query: 143 --NAERLMDDNDSENNQES-------------MPSLSFRQT------------------- 168
NA +D + E+ + L F+
Sbjct: 210 AANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWW 269
Query: 169 ------MWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVET------VPCGTVPGSKEL 216
+W FE+P++S A + + FFI +S+ T +ET + TV + +
Sbjct: 270 RRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPI 329
Query: 217 PCGERYSVAFFCLDT---------ACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAI 267
P ++ ++T CV+ FT E+L+R+ P + F++S ++IID VAI
Sbjct: 330 PGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAI 389
Query: 268 MPYYI-----GLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELG 322
+P+Y+ GL +DV G +R R+ RIFK +RH GLR+LG+TL++ +E
Sbjct: 390 LPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 449
Query: 323 FLLFSLTMAIIIFATVMFYAEK---------GSSASKFTSIPASFWYTIVTMTTLGYGDM 373
L+ L + ++IFAT+++YAE+ GS+ + F +IP FW+ +VTMTTLGYGDM
Sbjct: 450 LLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDM 509
Query: 374 VPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLAR 429
PKT +G + G++C+L+GVL IA+PVPVIV+NF Y K +K + R
Sbjct: 510 YPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPR 565
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 247 bits (631), Expect = 2e-65
Identities = 168/527 (31%), Positives = 267/527 (50%), Gaps = 82/527 (15%)
Query: 80 KEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDR 139
+E+FFDR P VF VLN+YRTGKLH P C +++ELAF+GI + CC+ Y R
Sbjct: 100 REFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTY--R 157
Query: 140 KRENAERLMD--------------DNDSENNQESMPSLS--------------FRQTMWR 171
+ +AE +D D D + + + + MW
Sbjct: 158 QHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWA 217
Query: 172 AFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSV------- 224
FE+P++S A + + FFI VS+ T +ET + +K P SV
Sbjct: 218 LFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIE 277
Query: 225 ---AFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYI-----GLVM 276
A ++ CV+ FT E+L+R+ +P++ FI+++++IID VAI+P+Y+ GL
Sbjct: 278 TDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSS 337
Query: 277 TNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFA 336
+DV G +R R+ RIFK +RH GLR+LG+TL++ +E L+ L + ++IFA
Sbjct: 338 KAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFA 397
Query: 337 TVMFYAEK---------GSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSIC 387
T+++YAE+ S ++F +IP FW+ +VTMTTLGYGDM P+T +G + G++C
Sbjct: 398 TMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALC 457
Query: 388 SLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRN 447
+L+GVL IA+PVPVIV+NF +Y+ A ++ +K+ + I A SS + ++ N
Sbjct: 458 ALAGVLTIAMPVPVIVNNFG-MYYSLAMAKQKLPRKRKK--HIPPAPQASSPTFCKTELN 514
Query: 448 GLLNEALELTGTPEEEHMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDP-LLSVRTSTIK 506
N T + +GK L+E H+ + + +TG + P L +R S+ +
Sbjct: 515 MACN------STQSDTCLGKDNRLLE--HNRSVLSGDDSTGSEPPLSPPERLPIRRSSTR 566
Query: 507 NHEFIDEQMF----------------EQNCMESSMQNYPSTRSPSLS 537
+ E F + NC E + Y + SL+
Sbjct: 567 DKNRRGETCFLLTTGDYTCASDGGIRKDNCKEVVITGYTQAEARSLT 613
Score = 32.0 bits (71), Expect = 1.8
Identities = 16/35 (45%), Positives = 24/35 (68%), Gaps = 3/35 (8%)
Query: 39 DELIVLNVSGRRFQTWRTTLERYPDT---LLGSTE 70
+E ++LNV G R +T+R+TL+ P T LL S+E
Sbjct: 7 NERVILNVGGTRHETYRSTLKTLPGTRLALLASSE 41
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 246 bits (628), Expect = 5e-65
Identities = 156/457 (34%), Positives = 244/457 (53%), Gaps = 65/457 (14%)
Query: 80 KEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDR 139
+E+FFDR P VF VLN+YRTGKLH P C +++ELAF+GI + CC+ Y R
Sbjct: 100 REFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTY--R 157
Query: 140 KRENAERLMD--------------DNDSENNQESMPSLS--------------FRQTMWR 171
+ +AE +D D D + + + + MW
Sbjct: 158 QHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWA 217
Query: 172 AFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSV------- 224
FE+P++S A + + FFI VS+ T +ET + +K P SV
Sbjct: 218 LFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIE 277
Query: 225 ---AFFCLDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYI-----GLVM 276
A ++ CV+ FT E+L+R+ +P++ FI+++++IID VAI+P+Y+ GL
Sbjct: 278 TDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSS 337
Query: 277 TNNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFA 336
+DV G +R R+ RIFK +RH GLR+LG+TL++ +E L+ L + ++IFA
Sbjct: 338 KAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFA 397
Query: 337 TVMFYAEK---------GSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSIC 387
T+++YAE+ S ++F +IP FW+ +VTMTTLGYGDM P+T +G + G++C
Sbjct: 398 TMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALC 457
Query: 388 SLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRN 447
+L+GVL IA+PVPVIV+NF +Y+ A ++ +K+ + I A SS + ++ N
Sbjct: 458 ALAGVLTIAMPVPVIVNNFG-MYYSLAMAKQKLPRKRKK--HIPPAPQASSPTFCKTELN 514
Query: 448 GLLNEALELTGTPEEEHMGKTTSLIESQHHHLLHCLE 484
N T + +GK L+E H+ +C E
Sbjct: 515 MACN------STQSDTCLGKDNRLLE--HNRSDNCKE 543
Score = 32.0 bits (71), Expect = 1.8
Identities = 16/35 (45%), Positives = 24/35 (68%), Gaps = 3/35 (8%)
Query: 39 DELIVLNVSGRRFQTWRTTLERYPDT---LLGSTE 70
+E ++LNV G R +T+R+TL+ P T LL S+E
Sbjct: 7 NERVILNVGGTRHETYRSTLKTLPGTRLALLASSE 41
>gi|4504821 potassium voltage-gated channel, shaker-related
subfamily, member 6 [Homo sapiens]
Length = 529
Score = 245 bits (626), Expect = 8e-65
Identities = 156/446 (34%), Positives = 234/446 (52%), Gaps = 78/446 (17%)
Query: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEF-FFNEDTKEYFFDRDPEVFRCVLNFY 98
E +V+N+SG RF+T TL +PDTLLG + FF+ EYFFDR+ F +L +Y
Sbjct: 41 ERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYY 100
Query: 99 RTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQ 157
++G +L P + + +E+ FY + E + RE+ L + + E
Sbjct: 101 QSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAF---------REDEGCLPEGGEDE--- 148
Query: 158 ESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPG----- 212
+ +PS F++ +W FE P +S A V+ I +S++ +ET+P V G
Sbjct: 149 KPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNN 208
Query: 213 ---SKELPC--------------------------------------GERYSVAFFCLDT 231
S+ P G ++ FF ++T
Sbjct: 209 GGVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVET 268
Query: 232 ACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGL-----VMTNNEDVSGA- 285
C++ FT E L+R A PS+ F R++M+IID+VAI PY+I L + SG
Sbjct: 269 LCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGG 328
Query: 286 ------------FVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAII 333
+R+ RVFRIFK SRHS+GL+ILG TL++ ELG L+F L + +I
Sbjct: 329 GQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVI 388
Query: 334 IFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVL 393
+F++ +++AE S F SIP +FW+ +VTMTT+GYGDM P T+ GKI GS+C+++GVL
Sbjct: 389 LFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVL 448
Query: 394 VIALPVPVIVSNFSRIYHQNQRADKR 419
IALPVPVIVSNF+ YH+ +++
Sbjct: 449 TIALPVPVIVSNFNYFYHRETEQEEQ 474
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 236 bits (601), Expect = 6e-62
Identities = 147/425 (34%), Positives = 225/425 (52%), Gaps = 44/425 (10%)
Query: 37 RQDELIVLNVSGRRFQTWRTTLERYPDTLLGS-----TEKEFF-----FNEDTKEYFFDR 86
+ +EL+ LNV G + ++TL R+P T LG +E+ ++ KEY+FDR
Sbjct: 12 QDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDR 71
Query: 87 DPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAER 146
+P +FR VLNFY TGKLH C+ ++ E+ ++GI I CC Y++RK EN E+
Sbjct: 72 NPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEK 131
Query: 147 LMDDNDS--------------ENNQESMPSLSF---RQTMWRAFENPHTSTLALVFYYVT 189
D E E +L F R+ +W ENP Y ++
Sbjct: 132 DWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPA--------YCLS 183
Query: 190 GFFIAVSVITNVVETVPCGTVPGSKELPC--GERYSVAFFCLDTACVMIFTVEYLLRLFA 247
IA+S ++ V+ ++ V E GE ++ AC+ FT E +RL A
Sbjct: 184 AKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAA 243
Query: 248 APSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVS------GAFVT-LRVFRVFRIFKF 300
AP + +F ++ ++IID V+I+P+Y L + E+ S G V LR+ R+FRI K
Sbjct: 244 APCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKL 303
Query: 301 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY 360
+RHS GLR LG TL+ E+G LL L++ I IF+ +++ EK S TSIP +W+
Sbjct: 304 ARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWW 363
Query: 361 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR 420
++MTT+GYGD P T+AGK+ S C + G+LV+ALP+ +I + FS+ Y + + D +
Sbjct: 364 ATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQ 423
Query: 421 AQKKA 425
+ A
Sbjct: 424 CSEDA 428
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 231 bits (589), Expect = 2e-60
Identities = 153/488 (31%), Positives = 250/488 (51%), Gaps = 46/488 (9%)
Query: 27 MPLAPADKNKRQDEL-IVLNVSGRRFQTWRTTLERYPDT--------LLGSTEKEFFFNE 77
+P + + D++ IV+NV G R + L +YP+T L G + F +
Sbjct: 9 LPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCD 68
Query: 78 D----TKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCY 133
D +E++FDRDP+ F+CV+ Y G++H + C + +E+ F+ + + + DCC
Sbjct: 69 DYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCK 128
Query: 134 EEYKDRKRE------NAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYY 187
+++ E + ++DD + + ++ +W+ E P +S A V
Sbjct: 129 SHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRC--QKCVWKFLEKPESSCPARVVAV 186
Query: 188 VTGFFIAVSVITNVVETVPCGTVPGSK----ELPCGERYSVAFFCLDTACVMIFTVEYLL 243
++ I VS + + T+P V ++ E P E ++TAC+ FT+EYLL
Sbjct: 187 LSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLEN-------VETACIGWFTLEYLL 239
Query: 244 RLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNN-------EDVSGAFVTLRVFRVFR 296
RLF++P++ F S M+I+DV+AI+P+Y+ L +T+ +V A LR+ R+ R
Sbjct: 240 RLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIAR 299
Query: 297 IFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPA 356
IFK +RHS GL+ L Y LK ELG LL L + I +F+ + + E+ + F SIP
Sbjct: 300 IFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQ 359
Query: 357 SFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRA 416
SFW+ I+TMTT+GYGD+ PKT GK+ +I L GV+ IALP+ I++NF R Y+ QR
Sbjct: 360 SFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVR-YYNKQRV 418
Query: 417 DKRRAQKKARLARIRVA-----KTGSSNAYLHS-KRNGLLNEALELTGTPEEEHMGKTTS 470
+ A+ + L + + KTG S + L + EA + + H
Sbjct: 419 LETAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIP 478
Query: 471 LIESQHHH 478
L+ + HH
Sbjct: 479 LLTEEKHH 486
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 226 bits (575), Expect = 7e-59
Identities = 147/443 (33%), Positives = 221/443 (49%), Gaps = 57/443 (12%)
Query: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGST--------------------EKEFFFNEDT 79
+ +NV G RF + L +P T LG E N
Sbjct: 39 DCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVD 98
Query: 80 KEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDR 139
EYFFDR + FR VL++YRTG+LH C ++ E+ ++GI I CC + Y R
Sbjct: 99 NEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRR 158
Query: 140 KR--ENAERLMDDNDSENNQESM------PSLSFRQTMWRAFENPHTSTLALVFYYVTGF 191
K E + D D E+ ES P + RQ +W E P +ST A +F ++
Sbjct: 159 KELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISII 218
Query: 192 FIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPSR 251
F+ VS+I + + + +L E L+ C+ FT E++LR R
Sbjct: 219 FVVVSIINMALMSAELSWL----DLQLLE-------ILEYVCISWFTGEFVLRFLCVRDR 267
Query: 252 YRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVT------------LRVFRVFRIFK 299
RF+R V +IID++AI+P+YI L++ E +SG+ T LR+ R R+ K
Sbjct: 268 CRFLRKVPNIIDLLAILPFYITLLV---ESLSGSQTTQELENVGRIVQVLRLLRALRMLK 324
Query: 300 FSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFW 359
RHS GLR LG T+ C E+G LL L++ I IF+TV ++AE+ + FTS+P ++W
Sbjct: 325 LGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWW 384
Query: 360 YTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKR 419
+ +MTT+GYGD+ P T GKI +C LSG+LV+ALP+ +I FS Y +
Sbjct: 385 WATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYF---TLKLK 441
Query: 420 RAQKKARLARIRVAKTGSSNAYL 442
A + R A ++ K ++++Y+
Sbjct: 442 EAAVRQREALKKLTKNIATDSYI 464
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 224 bits (570), Expect = 3e-58
Identities = 138/414 (33%), Positives = 221/414 (53%), Gaps = 38/414 (9%)
Query: 38 QDELIVLNVSGRRFQTWRTTLERYPDTLLGST----EKEFF------FNEDTKEYFFDRD 87
+D I +NV G + + TL R+P+T LG +E +++ +E++FDR+
Sbjct: 15 EDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRN 74
Query: 88 PEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERL 147
PE+F VL+FY TGKLH C+ ++ E+ ++GI I CC Y RK E +
Sbjct: 75 PELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEK 134
Query: 148 MDDNDSENNQES-----------------MPSLSFRQTMWRAFENPHTSTLALVFYYVTG 190
D+ + + S P +FR+ +W A +NP S L+ VF ++
Sbjct: 135 WDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSI 194
Query: 191 FFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPS 250
+ S+IT + ++P +P S+ P GE F ++ + FT E + R AP
Sbjct: 195 LVVMGSIITMCLNSLPDFQIPDSQGNP-GE--DPRFEIVEHFGIAWFTFELVARFAVAPD 251
Query: 251 RYRFIRSVMSIIDVVAIMPYYIGLVMT-------NNEDVSGAFVTLRVFRVFRIFKFSRH 303
+F ++ +++ID+++I+P+YI LV+ ++ LR+ R+FRI K +RH
Sbjct: 252 FLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLANLGRVAQVLRLMRIFRILKLARH 311
Query: 304 SQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIV 363
S GLR LG TLK E+G LL L++ I IF+ V + EK + T IPA +W+ V
Sbjct: 312 STGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEENEGLAT-IPACWWWATV 370
Query: 364 TMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD 417
+MTT+GYGD+VP T AGK+ S C L+G+LV+ LP+ +I + FS Y + ++ +
Sbjct: 371 SMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLE 424
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 222 bits (566), Expect = 7e-58
Identities = 145/432 (33%), Positives = 223/432 (51%), Gaps = 46/432 (10%)
Query: 31 PADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNE----------DTK 80
P D+ +R I++NV G ++ TTL+ +P T LG + F++
Sbjct: 58 PEDRRRR----IIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCN 113
Query: 81 EYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRK 140
E+FFDR+P F +L F R GKL R C ++ +EL ++GI + + CC Y +
Sbjct: 114 EFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKI 173
Query: 141 RENAERL----------MDDNDSENNQESMPSLSFRQTMWRAF-ENPHTSTLALVFYYVT 189
E AE + + DSE E L R E PH+ VF ++
Sbjct: 174 EEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLS 233
Query: 190 GFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAP 249
F+ V+ + V T+P ++ +E + F +++ CV F++E+LLRL AP
Sbjct: 234 VLFVTVTAVNLSVSTLP--SLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAP 291
Query: 250 SRYRFIRSVMSIIDVVAIMPYYIGLVM-----------TNNEDVSGAFVTLRVFRVFRIF 298
S++ F+RS +++ID+VAI+PYYI L++ N + + LRV R RI
Sbjct: 292 SKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRIL 351
Query: 299 ---KFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSAS-KFTSI 354
+ +RHS GL+ LG T + C E G LL L +AI +FA +++ E + S +FTSI
Sbjct: 352 YVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSI 411
Query: 355 PASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY---- 410
PA +W+ ++TMTT+GYGDMVP++ G++ LSG+L++A PV I FSR Y
Sbjct: 412 PACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELK 471
Query: 411 HQNQRADKRRAQ 422
+ +R RRAQ
Sbjct: 472 QEQERVMFRRAQ 483
>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
[Homo sapiens]
Length = 466
Score = 211 bits (538), Expect = 1e-54
Identities = 134/434 (30%), Positives = 219/434 (50%), Gaps = 39/434 (8%)
Query: 26 PMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYP-------------DTLLGSTEKE 72
P P +P + +++NV G R + L R P D LL +
Sbjct: 3 PWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDD- 61
Query: 73 FFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCC 132
++ E+FFDR P FR ++ R GKL R C A+ DELA++GI + CC
Sbjct: 62 --YDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC 119
Query: 133 YEEYKDRKRENAERLMDDNDSENNQESMPSLSF---------RQTMWRAFENPHTSTLAL 183
+ R+ E AE +E + P+ + R+ + +NPH+
Sbjct: 120 LRRLRRREEEAAEARA--GPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGK 177
Query: 184 VFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLL 243
+F V+ F+AV+ + + T+P + +E + F L+T CV F+ E+LL
Sbjct: 178 LFACVSVSFVAVTAVGLCLSTMP--DIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLL 235
Query: 244 RLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVT---------LRVFRV 294
R A S+ F+R+ ++IID++A++P+Y+ L++ G + LR RV
Sbjct: 236 RSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRV 295
Query: 295 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASK-FTS 353
+ + +RHS GLR LG T++ CA E G LL L +A+ +FA ++ AE+ A + F+S
Sbjct: 296 LYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSS 355
Query: 354 IPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQN 413
+PAS+W+ +++MTT+GYGDMVP+++ G++ LSG+L++A PV I FSR Y +
Sbjct: 356 VPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSEL 415
Query: 414 QRADKRRAQKKARL 427
+ +R A + L
Sbjct: 416 KEQQQRAASPEPAL 429
>gi|27436996 potassium voltage-gated channel, subfamily G, member 4
[Homo sapiens]
Length = 519
Score = 207 bits (527), Expect = 2e-53
Identities = 135/437 (30%), Positives = 220/437 (50%), Gaps = 45/437 (10%)
Query: 30 APADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTE-----KEFF-----FNEDT 79
+P D K I++NV GRR+ +TL+R+P + L +E ++ED+
Sbjct: 53 SPVDLKKE----ILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDS 108
Query: 80 KEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDR 139
+E+FFDR P F +++F GKL + C ++ +ELA++GI + CC + R
Sbjct: 109 QEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLL-R 167
Query: 140 KRENAERL--MDDNDSENNQESMPSLSFRQTMW--------RAFENPHTSTLALVFYYVT 189
K E E L + D Q + + W ENP + VF ++
Sbjct: 168 KLEELEELAKLHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLS 227
Query: 190 GFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAP 249
F+A + ++ V T+P + ++ R F ++T CV F++E+ LR A
Sbjct: 228 ILFVATTAVSLCVSTMP--DLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQ 285
Query: 250 SRYRFIRSVMSIIDVVAIMPYYIGLVMTNN--------------EDVSGAFVTLRVFRVF 295
+ +F + ++IID++AI PYY+ L ++ E V LR R+
Sbjct: 286 DKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRIL 345
Query: 296 RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSS-ASKFTSI 354
+ + +RHS GL+ LG T++ C E G LL L +AI +F+ +++ AEK S +FTSI
Sbjct: 346 YVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSI 405
Query: 355 PASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ 414
PAS+W+ I++MTT+GYGDMVP+++ G++ LSG+L++A P I FS H
Sbjct: 406 PASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFS---HSYL 462
Query: 415 RADKRRAQKKARLARIR 431
K + Q +ARL ++
Sbjct: 463 ELKKEQEQLQARLRHLQ 479
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,150,878
Number of Sequences: 37866
Number of extensions: 1188684
Number of successful extensions: 7264
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 106
Number of HSP's that attempted gapping in prelim test: 6117
Number of HSP's gapped (non-prelim): 1031
length of query: 655
length of database: 18,247,518
effective HSP length: 109
effective length of query: 546
effective length of database: 14,120,124
effective search space: 7709587704
effective search space used: 7709587704
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.