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Search of human proteins with 25952092
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
(456 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25952092 potassium voltage-gated channel, shaker-related subf... 925 0.0
gi|88758565 potassium voltage-gated channel, shaker-related subf... 582 e-166
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 569 e-162
gi|119395748 potassium voltage-gated channel subfamily A member ... 568 e-162
gi|4504821 potassium voltage-gated channel, shaker-related subfa... 566 e-161
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 561 e-160
gi|25952087 potassium voltage-gated channel, shaker-related subf... 552 e-157
gi|5031819 potassium voltage-gated channel, shaker-related subfa... 528 e-150
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 274 1e-73
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 268 6e-72
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 268 1e-71
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 268 1e-71
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 265 8e-71
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 263 2e-70
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 263 2e-70
gi|163792201 Shaw-related voltage-gated potassium channel protei... 263 2e-70
gi|88758576 Shaw-related voltage-gated potassium channel protein... 261 7e-70
gi|24497462 Shaw-related voltage-gated potassium channel protein... 261 7e-70
gi|24497464 Shaw-related voltage-gated potassium channel protein... 261 7e-70
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 254 1e-67
gi|21217561 Shaw-related voltage-gated potassium channel protein... 251 7e-67
gi|21217563 Shaw-related voltage-gated potassium channel protein... 251 7e-67
gi|24497458 Shaw-related voltage-gated potassium channel protein... 251 7e-67
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 239 5e-63
gi|24497460 Shaw-related voltage-gated potassium channel protein... 238 1e-62
gi|19071574 potassium voltage-gated channel, subfamily G, member... 224 1e-58
gi|27436993 potassium voltage-gated channel, subfamily G, member... 217 2e-56
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 214 2e-55
gi|27436988 potassium voltage-gated channel, subfamily G, member... 211 1e-54
gi|20070166 potassium voltage-gated channel, subfamily F, member... 210 2e-54
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 925 bits (2391), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDR 60
MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDR
Sbjct: 1 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDR 60
Query: 61 HRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPL 120
HRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPL
Sbjct: 61 HRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPL 120
Query: 121 PRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAA 180
PRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAA
Sbjct: 121 PRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAA 180
Query: 181 AAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKN 240
AAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKN
Sbjct: 181 AAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKN 240
Query: 241 VMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQI 300
VMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQI
Sbjct: 241 VMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQI 300
Query: 301 LGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVG 360
LGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVG
Sbjct: 301 LGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVG 360
Query: 361 YGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQP 420
YGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQP
Sbjct: 361 YGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQP 420
Query: 421 CGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVTEV 456
CGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVTEV
Sbjct: 421 CGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVTEV 456
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 582 bits (1500), Expect = e-166
Identities = 290/406 (71%), Positives = 337/406 (83%), Gaps = 5/406 (1%)
Query: 11 CCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLY 70
C ER+V+N++GLRFET+ +TL +FP+TLLGDP RR R++D R EYFFDR+RPSFDA+LY
Sbjct: 102 CGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILY 161
Query: 71 YYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLW 130
YYQSGGR+RRP +VP+D+F EE+ FY LG A+ + REDEG ERPLPRR F RQ+W
Sbjct: 162 YYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVW 221
Query: 131 LLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPL 190
LLFE+PESS AR +A+VSVLVIL+SIV+FCLETLP+FRD++D A+ + F A
Sbjct: 222 LLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKD---YPASTSQDSFEAA- 277
Query: 191 NGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAI 250
G+S F+DPFFVVETLCI WFSFELLVR CPSKA F +N+MNLID VAI
Sbjct: 278 -GNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAI 336
Query: 251 LPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMR 310
+PYF+ LGTELA ++G GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTL+ASMR
Sbjct: 337 IPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMR 396
Query: 311 ELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVG 370
ELGLLIFFLFIGV+LFSSAVYFAE D S F+SIP++FWWAVVTMTTVGYGDM PVT+G
Sbjct: 397 ELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIG 456
Query: 371 GKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHV 416
GKIVGSLCAIAGVLTI+LPVPVIVSNF+YFYHRETEGEE + HV
Sbjct: 457 GKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQYMHV 502
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 569 bits (1466), Expect = e-162
Identities = 285/405 (70%), Positives = 332/405 (81%), Gaps = 9/405 (2%)
Query: 11 CCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLY 70
CCER+V+NV+GLRFET+ +TL +FP+TLLGDP +R +++D R EYFFDR+RPSFDA+LY
Sbjct: 174 CCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILY 233
Query: 71 YYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPE-RPLPRRAFARQL 129
YYQSGGRL+RP +VP D+F EEV FY LG AL + REDEG E R LP F +Q+
Sbjct: 234 YYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQI 293
Query: 130 WLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAP 189
WLLFE+PESS AR +A+VSVLVIL+SIV+FCLETLP+FRDDRD L A +AG
Sbjct: 294 WLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRD---LVMALSAGGHGGL 350
Query: 190 LNGSSQMP-GNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFV 248
LN +S N FNDPFF+VET+CI WFSFE +VR CPS+A+FFKN+MN+ID V
Sbjct: 351 LNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIV 410
Query: 249 AILPYFVALGTELARQRGVG----QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQT 304
+ILPYF+ LGT+LA+Q+G G QQAMS AILR+IRLVRVFRIFKLSRHSKGLQILG T
Sbjct: 411 SILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHT 470
Query: 305 LRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDM 364
LRASMRELGLLIFFLFIGV+LFSSAVYFAE D +HF SIP++FWWAVVTMTTVGYGDM
Sbjct: 471 LRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDM 530
Query: 365 APVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
P+TVGGKIVGSLCAIAGVLTI+LPVPVIVSNF+YFYHRETE EE
Sbjct: 531 KPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEE 575
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 568 bits (1465), Expect = e-162
Identities = 281/408 (68%), Positives = 331/408 (81%), Gaps = 14/408 (3%)
Query: 11 CCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLY 70
CCER+V+N++GLRFET+ +TL +FP+TLLG+P +R R++D R EYFFDR+RPSFDA+LY
Sbjct: 35 CCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILY 94
Query: 71 YYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLW 130
YYQSGGRLRRP +VPLD+F EE+ FY LG A+ + REDEG ERPLP + + RQ+W
Sbjct: 95 YYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVW 154
Query: 131 LLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPL 190
LLFE+PESS ARV+A+VSV+VIL+SIV+FCLETLP+ +DD+D TG
Sbjct: 155 LLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRID-------- 206
Query: 191 NGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAI 250
N + N F DPFF+VETLCI WFSFEL+VR CPSK FFKN+MN ID VAI
Sbjct: 207 NTTVIYNSNI----FTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAI 262
Query: 251 LPYFVALGTELARQRG--VGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRAS 308
+PYF+ LGTE+A Q G G+QA SLAILRVIRLVRVFRIFKLSRHSKGLQILGQTL+AS
Sbjct: 263 IPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKAS 322
Query: 309 MRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVT 368
MRELGLLIFFLFIGV+LFSSAVYFAE + +SHF+SIP++FWWAVV+MTTVGYGDM PVT
Sbjct: 323 MRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVT 382
Query: 369 VGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHV 416
+GGKIVGSLCAIAGVLTI+LPVPVIVSNF+YFYHRETEGEE HV
Sbjct: 383 IGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHV 430
>gi|4504821 potassium voltage-gated channel, shaker-related
subfamily, member 6 [Homo sapiens]
Length = 529
Score = 567 bits (1460), Expect = e-161
Identities = 308/495 (62%), Positives = 351/495 (70%), Gaps = 49/495 (9%)
Query: 10 GCC--ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDA 67
GCC ERLV+N++GLRFET+ RTL FPDTLLGDP RR RF+D R EYFFDR+RPSFDA
Sbjct: 36 GCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDA 95
Query: 68 VLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPP----ERPLPRR 123
+LYYYQSGGRLRRP +VPLD+FLEE+ FY LG ALA REDEGC +P E+PLP +
Sbjct: 96 ILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGC-LPEGGEDEKPLPSQ 154
Query: 124 AFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAA 183
F RQ+WLLFE+PESS AR +A+VSVLVIL+SIV+FCLETLP FR D G +
Sbjct: 155 PFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRV 214
Query: 184 GP-----------------FPAPLNGSSQMPGNPPRLP------FNDPFFVVETLCICWF 220
P F + G L F DPFF+VETLCI WF
Sbjct: 215 SPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWF 274
Query: 221 SFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGV----------GQQ 270
+FELLVR CPSK FF+N+MN+ID VAI PYF+ LGTEL +Q+ GQQ
Sbjct: 275 TFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQ 334
Query: 271 AMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAV 330
AMSLAILRVIRLVRVFRIFKLSRHSKGLQILG+TL+ASMRELGLLIFFLFIGV+LFSSAV
Sbjct: 335 AMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAV 394
Query: 331 YFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPV 390
YFAE D DS F SIP++FWWAVVTMTTVGYGDM P+TVGGKIVGSLCAIAGVLTI+LPV
Sbjct: 395 YFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPV 454
Query: 391 PVIVSNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPE---------LP 441
PVIVSNF+YFYHRETE EE G ++HV P + GL + PE LP
Sbjct: 455 PVIVSNFNYFYHRETEQEEQGQYTHVTCGQPAPDLRATDNGLGKPDFPEANRERRPSYLP 514
Query: 442 PPLWAPPGKHLVTEV 456
P A K ++TEV
Sbjct: 515 TPHRAYAEKRMLTEV 529
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 561 bits (1446), Expect = e-160
Identities = 282/416 (67%), Positives = 327/416 (78%), Gaps = 16/416 (3%)
Query: 11 CCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLY 70
CCER+V+N++GLRFET+ +TL +FP+TLLGDP +R R++D R EYFFDR+RPSFDA+LY
Sbjct: 31 CCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILY 90
Query: 71 YYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLW 130
YYQSGGRLRRP +VPLD+F EE+ FY LG A+ REDEG ERPLP F RQ+W
Sbjct: 91 YYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVW 150
Query: 131 LLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRD---GTGLAAAAAAGPFP 187
LLFE+PESS AR++A+VSV+VIL+SIV FCLETLP FRD+ + G+G+
Sbjct: 151 LLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTY----- 205
Query: 188 APLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDF 247
S+ G F DPFF+VETLCI WFSFE LVR CPSKA FF N+MN+ID
Sbjct: 206 -----SNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDI 260
Query: 248 VAILPYFVALGTELARQ---RGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQT 304
VAI+PYF+ LGTELA + GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQT
Sbjct: 261 VAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQT 320
Query: 305 LRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDM 364
L+ASMRELGLLIFFLFIGV+LFSSAVYFAE D +S F SIP++FWWAVV+MTTVGYGDM
Sbjct: 321 LKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDM 380
Query: 365 APVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQP 420
P T+GGKIVGSLCAIAGVLTI+LPVPVIVSNF+YFYHRETEGEE + V P
Sbjct: 381 VPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCP 436
>gi|25952087 potassium voltage-gated channel, shaker-related
subfamily, member 5 [Homo sapiens]
Length = 613
Score = 552 bits (1423), Expect = e-157
Identities = 282/412 (68%), Positives = 330/412 (80%), Gaps = 15/412 (3%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYY 72
+R+ +N++GLRFET+ TL +FP+TLLGDPA+R R++D R EYFFDR+RPSFD +LYYY
Sbjct: 120 QRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYY 179
Query: 73 QSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLWLL 132
QSGGRLRRP +V LDVF +E+ FY LG A+ R REDEG E+PLPR F RQ+WL+
Sbjct: 180 QSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLI 239
Query: 133 FEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAP-LN 191
FE+PESS +AR +A+VSVLVIL+SI+ FCLETLP+FRD+R+ A P PAP N
Sbjct: 240 FEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGAN 299
Query: 192 GSSQM--PGNP---PRLP--FNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNL 244
GS M P P P LP DPFF+VET C+ WF+FELLVR CPSKA F +N+MN+
Sbjct: 300 GSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNI 359
Query: 245 IDFVAILPYFVALGTELARQRGVG-------QQAMSLAILRVIRLVRVFRIFKLSRHSKG 297
ID VAI PYF+ LGTELA Q+ G QQAMSLAILRVIRLVRVFRIFKLSRHSKG
Sbjct: 360 IDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKG 419
Query: 298 LQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMT 357
LQILG+TL+ASMRELGLLIFFLFIGV+LFSSAVYFAE D +HF+SIP++FWWAVVTMT
Sbjct: 420 LQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMT 479
Query: 358 TVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
TVGYGDM P+TVGGKIVGSLCAIAGVLTI+LPVPVIVSNF+YFYHRET+ EE
Sbjct: 480 TVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEE 531
>gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
Length = 511
Score = 528 bits (1360), Expect = e-150
Identities = 262/398 (65%), Positives = 320/398 (80%), Gaps = 12/398 (3%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYY 72
+R+++N+AGLRFET+ RTL +FP+TLLGD +R +F+D R EYFFDR+RPSFD +LYYY
Sbjct: 86 QRVIINIAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYY 145
Query: 73 QSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLWLL 132
QSGG++RRPA+VP+D+F +E++FY LG+ A+ + REDEG PE LP RQ WLL
Sbjct: 146 QSGGKIRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLL 205
Query: 133 FEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNG 192
FE+PESS AAR +AVVSVLV+++SI +FCLETLP+FR+DR+ P LN
Sbjct: 206 FEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRE-----LKVVRDP---NLNM 257
Query: 193 SSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILP 252
S + + F DPFF+VE+ CI WF+FEL++R +VCPSK FF+N+MN+ID ++I+P
Sbjct: 258 SKTVLS---QTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIP 314
Query: 253 YFVALGTELARQ-RGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRE 311
YF L TEL ++ QQ MSLAILR+IRLVRVFRIFKLSRHSKGLQILGQTL+ASMRE
Sbjct: 315 YFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRE 374
Query: 312 LGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGG 371
LGLLIFFLFIGV+LFSSAVYFAEVD +SHF+SIP+ FWWAVVTMTTVGYGDM P T GG
Sbjct: 375 LGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGG 434
Query: 372 KIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
KIVG+LCAIAGVLTI+LPVPVIVSNF+YFYHRETE EE
Sbjct: 435 KIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEE 472
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 274 bits (700), Expect = 1e-73
Identities = 180/451 (39%), Positives = 250/451 (55%), Gaps = 62/451 (13%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYY 72
E LV+NV+G RFET TL R+PDTLLG + + FYD EYFFDR F VL +Y
Sbjct: 40 EVLVVNVSGRRFETWKNTLDRYPDTLLGS-SEKEFFYDADSGEYFFDRDPDMFRHVLNFY 98
Query: 73 QSGGRLRRPAHVPLDVFLEEVAFYGL-----GAAALA-----------RLREDEGCPVPP 116
++G RL P + F EE+AFYGL G L RL EDE
Sbjct: 99 RTG-RLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAG 157
Query: 117 ERP-LPRRAFARQ-LWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDG 174
+ P LP + RQ LW FE P +S AA V V+ I VS++ +ET+P
Sbjct: 158 DGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIP-------- 209
Query: 175 TGLAAAAAAGPFPAPLNGSSQMPGN--PPRLPFNDPFFVVETLCICWFSFELLVRLLVCP 232
GS++ P F FF ++T C+ F+ E L+RL P
Sbjct: 210 ---------------CRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEYLLRLFAAP 254
Query: 233 SKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLS 292
S+ F ++VM+LID VAILPY++ G + + V ++L R+ RVFRIFK S
Sbjct: 255 SRCRFLRSVMSLIDVVAILPYYI--GLLVPKNDDVSGAFVTL------RVFRVFRIFKFS 306
Query: 293 RHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWA 352
RHS+GL+ILG TL++ ELG L+F L + +++F++ +++AE ++FTSIP +FW+
Sbjct: 307 RHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAAFWYT 366
Query: 353 VVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHR-----ETEG 407
+VTMTT+GYGDM P T+ GKI GS+C+++GVL I+LPVPVIVSNFS YH+ +
Sbjct: 367 IVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRA 426
Query: 408 EEAGMFSHVDMQPCGP----LEGKANGGLVD 434
++ + + + G L+ K NGGL D
Sbjct: 427 QQKVRLARIRLAKSGTTNAFLQYKQNGGLED 457
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 268 bits (686), Expect = 6e-72
Identities = 161/415 (38%), Positives = 235/415 (56%), Gaps = 56/415 (13%)
Query: 15 LVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYYQS 74
+VLNV+G RF+T TL R+PDTLLG + R FY ++YFFDR F +L +Y++
Sbjct: 43 IVLNVSGTRFQTWQDTLERYPDTLLGS-SERDFFYHPETQQYFFDRDPDIFRHILNFYRT 101
Query: 75 GGRLRRPAHVPLDVFLEEVAFYGLGAAALA----------------RLREDEGCPVPPER 118
G +L P H + + EE+AF+GL + RL++D E
Sbjct: 102 G-KLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGES 160
Query: 119 PLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLA 178
LP +++W FE P +S A V V+ I VS++ +ET+P
Sbjct: 161 ALPTMTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANVVETVPC----------- 209
Query: 179 AAAAAGPFPAPLNGSSQMPGNPPRLPFND----PFFVVETLCICWFSFELLVRLLVCPSK 234
GSS PG+ LP + FF ++T C+ F+ E L+RL PS+
Sbjct: 210 -------------GSS--PGHIKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSR 254
Query: 235 AIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRH 294
F ++VM++ID VAILPY++ L + +S A + +R+ RVFRIFK SRH
Sbjct: 255 YRFVRSVMSIIDVVAILPYYIGLVM-------TDNEDVSGAFV-TLRVFRVFRIFKFSRH 306
Query: 295 SKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVV 354
S+GL+ILG TL++ ELG L+F L + +++F++ +++AE S FTSIP +FW+ +V
Sbjct: 307 SQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIV 366
Query: 355 TMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
TMTT+GYGDM P T+ GKI GS+C+++GVL I+LPVPVIVSNFS YH+ ++
Sbjct: 367 TMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADK 421
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 268 bits (684), Expect = 1e-71
Identities = 159/412 (38%), Positives = 236/412 (57%), Gaps = 48/412 (11%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYY 72
E +VLNV+G RF+T TL R+PDTLLG + F +D + EYFFDR F VL +Y
Sbjct: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTK-EYFFDRDPEVFRCVLNFY 98
Query: 73 QSGGRLRRPAHVPLDVFLEEVAFYGLGAAALA---------RLRE------DEGCPVPPE 117
++G +L P + + + +E+AFYG+ + R RE D+ +
Sbjct: 99 RTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQ 157
Query: 118 RPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGL 177
+P +F + +W FE P +S A V V+ I VS++ +ET+P
Sbjct: 158 ESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP----------- 206
Query: 178 AAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIF 237
G P GS ++P ++ FF ++T C+ F+ E L+RL PS+ F
Sbjct: 207 -----CGTVP----GSKELPCGER---YSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRF 254
Query: 238 FKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKG 297
++VM++ID VAI+PY++ G + V ++L R+ RVFRIFK SRHS+G
Sbjct: 255 IRSVMSIIDVVAIMPYYI--GLVMTNNEDVSGAFVTL------RVFRVFRIFKFSRHSQG 306
Query: 298 LQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMT 357
L+ILG TL++ ELG L+F L + +++F++ +++AE S FTSIP SFW+ +VTMT
Sbjct: 307 LRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMT 366
Query: 358 TVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
T+GYGDM P T+ GKI GS+C+++GVL I+LPVPVIVSNFS YH+ ++
Sbjct: 367 TLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADK 418
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 268 bits (684), Expect = 1e-71
Identities = 159/412 (38%), Positives = 236/412 (57%), Gaps = 48/412 (11%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYY 72
E +VLNV+G RF+T TL R+PDTLLG + F +D + EYFFDR F VL +Y
Sbjct: 40 ELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTK-EYFFDRDPEVFRCVLNFY 98
Query: 73 QSGGRLRRPAHVPLDVFLEEVAFYGLGAAALA---------RLRE------DEGCPVPPE 117
++G +L P + + + +E+AFYG+ + R RE D+ +
Sbjct: 99 RTG-KLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQ 157
Query: 118 RPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGL 177
+P +F + +W FE P +S A V V+ I VS++ +ET+P
Sbjct: 158 ESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVP----------- 206
Query: 178 AAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIF 237
G P GS ++P ++ FF ++T C+ F+ E L+RL PS+ F
Sbjct: 207 -----CGTVP----GSKELPCGER---YSVAFFCLDTACVMIFTVEYLLRLFAAPSRYRF 254
Query: 238 FKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKG 297
++VM++ID VAI+PY++ G + V ++L R+ RVFRIFK SRHS+G
Sbjct: 255 IRSVMSIIDVVAIMPYYI--GLVMTNNEDVSGAFVTL------RVFRVFRIFKFSRHSQG 306
Query: 298 LQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMT 357
L+ILG TL++ ELG L+F L + +++F++ +++AE S FTSIP SFW+ +VTMT
Sbjct: 307 LRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMT 366
Query: 358 TVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEE 409
T+GYGDM P T+ GKI GS+C+++GVL I+LPVPVIVSNFS YH+ ++
Sbjct: 367 TLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADK 418
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 265 bits (676), Expect = 8e-71
Identities = 170/433 (39%), Positives = 231/433 (53%), Gaps = 65/433 (15%)
Query: 11 CCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARR----------EYFFDR 60
C R+ LNV GL E RTL R P T LG R +D EYFFDR
Sbjct: 29 CSRRVRLNVGGLAHEVLWRTLDRLPRTRLGK-LRDCNTHDSLLEVCDDYSLDDNEYFFDR 87
Query: 61 HRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALAR--------------- 105
H +F ++L +Y++G RL + F +E+ ++G+ L
Sbjct: 88 HPGAFTSILNFYRTG-RLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNE 146
Query: 106 --------LREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSI 157
LRE EG +R ++LW L E P SS AA++LA++S++ I++S
Sbjct: 147 ELKREAETLREREGEEFDNTCCAEKR---KKLWDLLEKPNSSVAAKILAIISIMFIVLST 203
Query: 158 VVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCI 217
+ L TLP+ + L+ Q NP VE +CI
Sbjct: 204 IALSLNTLPELQS-------------------LDEFGQSTDNPQLAH-------VEAVCI 237
Query: 218 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAIL 277
WF+ E L+R L P K FFK +N ID +AILPY+V + + + V Q ++
Sbjct: 238 AWFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIFLTESN-KSVLQFQNVRRVV 296
Query: 278 RVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDR 337
++ R++R+ RI KL+RHS GLQ LG TLR S ELGLLI FL +G+++FSS V+FAE D
Sbjct: 297 QIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDE 356
Query: 338 VDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNF 397
D+ F SIP SFWWA +TMTTVGYGD+ P T+ GKIVG LC IAGVL I+LP+P+IV+NF
Sbjct: 357 DDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNF 416
Query: 398 SYFYHRETEGEEA 410
S FY + E+A
Sbjct: 417 SEFYKEQKRQEKA 429
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 263 bits (673), Expect = 2e-70
Identities = 167/432 (38%), Positives = 234/432 (54%), Gaps = 63/432 (14%)
Query: 11 CCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRF---------YDDARREYFFDRH 61
C R+ +NV GL E RTL R P T LG Y+ EYFFDRH
Sbjct: 33 CSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRH 92
Query: 62 RPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALAR---------------- 105
+F ++L +Y++G +L + F +E+ ++G+ L
Sbjct: 93 PGAFTSILNFYRTG-KLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEE 151
Query: 106 -------LREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIV 158
+RE EG +R ++LW L E P SS AA++LA+VS+L I++S +
Sbjct: 152 LRREAETMREREGEEFDNTCCPDKR---KKLWDLLEKPNSSVAAKILAIVSILFIVLSTI 208
Query: 159 VFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCIC 218
L TLP+ ++ + LN + Q+ VE +CI
Sbjct: 209 ALSLNTLPELQETDEF-------------GQLNDNRQLAH-------------VEAVCIA 242
Query: 219 WFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILR 278
WF+ E L+R L P+K FFK +N+ID +AILPY+V + + + V Q +++
Sbjct: 243 WFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESN-KSVLQFQNVRRVVQ 301
Query: 279 VIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRV 338
+ R++R+ RI KL+RHS GLQ LG TLR S ELGLLI FL +G+++FSS V+FAE D
Sbjct: 302 IFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDED 361
Query: 339 DSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFS 398
+ FTSIP SFWWA +TMTTVGYGD+ P T+ GKIVG LC IAGVL I+LP+P+IV+NFS
Sbjct: 362 ATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFS 421
Query: 399 YFYHRETEGEEA 410
FY + E+A
Sbjct: 422 EFYKEQKRQEKA 433
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 263 bits (673), Expect = 2e-70
Identities = 175/454 (38%), Positives = 239/454 (52%), Gaps = 83/454 (18%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLG---DPARRGRF-YDDARREYFFDRHRPSFDAV 68
ER+V+NV G R +T TL P T L +P F YD E+FFDRH F +
Sbjct: 8 ERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHI 67
Query: 69 LYYYQSGGRLRRPAHVPLDVFLEEVAFYGL--------------------------GAAA 102
L YY++G +L PA V ++ EE+AF+G+ G A
Sbjct: 68 LNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAP 126
Query: 103 LARLREDEGCPVP------------------PERPLPR-----RAFARQLWLLFEFPESS 139
L +D P + P R R + ++W LFE P SS
Sbjct: 127 LDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSS 186
Query: 140 QAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGN 199
+ AR +A S+ ILVSI FCLET F + T + NG+
Sbjct: 187 RYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVR---------NGTQV---R 234
Query: 200 PPRLPFNDPFFV-VETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALG 258
R + F +E +C+ WF+FE L+R++ CP+K F KN +N+IDFVAILP+++ +G
Sbjct: 235 YYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVG 294
Query: 259 TELARQRGVGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLI 316
G+ +A L LRV+R VR+ RIFKL+RH GL++LG TLRAS E LLI
Sbjct: 295 LS-----GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLI 349
Query: 317 FFLFIGVVLFSSAVYFAEVDRVD---------SHFTSIPESFWWAVVTMTTVGYGDMAPV 367
FL +GV++F++ +Y+AE +HF +IP FWWAVVTMTT+GYGDM P
Sbjct: 350 IFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQ 409
Query: 368 TVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFY 401
T G +VG+LCA+AGVLTI++PVPVIV+NF +Y
Sbjct: 410 TWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 263 bits (673), Expect = 2e-70
Identities = 175/454 (38%), Positives = 239/454 (52%), Gaps = 83/454 (18%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLG---DPARRGRF-YDDARREYFFDRHRPSFDAV 68
ER+V+NV G R +T TL P T L +P F YD E+FFDRH F +
Sbjct: 8 ERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHI 67
Query: 69 LYYYQSGGRLRRPAHVPLDVFLEEVAFYGL--------------------------GAAA 102
L YY++G +L PA V ++ EE+AF+G+ G A
Sbjct: 68 LNYYRTG-KLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAP 126
Query: 103 LARLREDEGCPVP------------------PERPLPR-----RAFARQLWLLFEFPESS 139
L +D P + P R R + ++W LFE P SS
Sbjct: 127 LDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSS 186
Query: 140 QAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGN 199
+ AR +A S+ ILVSI FCLET F + T + NG+
Sbjct: 187 RYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVR---------NGTQV---R 234
Query: 200 PPRLPFNDPFFV-VETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALG 258
R + F +E +C+ WF+FE L+R++ CP+K F KN +N+IDFVAILP+++ +G
Sbjct: 235 YYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVG 294
Query: 259 TELARQRGVGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLI 316
G+ +A L LRV+R VR+ RIFKL+RH GL++LG TLRAS E LLI
Sbjct: 295 LS-----GLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLI 349
Query: 317 FFLFIGVVLFSSAVYFAEVDRVD---------SHFTSIPESFWWAVVTMTTVGYGDMAPV 367
FL +GV++F++ +Y+AE +HF +IP FWWAVVTMTT+GYGDM P
Sbjct: 350 IFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQ 409
Query: 368 TVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFY 401
T G +VG+LCA+AGVLTI++PVPVIV+NF +Y
Sbjct: 410 TWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 443
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 261 bits (668), Expect = 7e-70
Identities = 181/467 (38%), Positives = 240/467 (51%), Gaps = 101/467 (21%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLG---DPARRGRFYDDARR------------EYF 57
E++++NV G R ET TL P T L DP GR D E+F
Sbjct: 36 EKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFF 95
Query: 58 FDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGL------------------- 98
FDRH F VL YY++G +L PA V +F EE+ F+G+
Sbjct: 96 FDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDA 154
Query: 99 ---------------GAA------------ALARLREDEGCPVPPERPLPRRAFARQLWL 131
GA AL RL EG R + ++W
Sbjct: 155 EEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWA 214
Query: 132 LFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLN 191
LFE P SS+AARV+A S+ ILVSI FCLET F DR+ T +
Sbjct: 215 LFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRV----------- 263
Query: 192 GSSQMPGNPPRLPFN-----DPFFV-VETLCICWFSFELLVRLLVCPSKAIFFKNVMNLI 245
GN + F +P +E +C+ WF+ E LVR++ CP F KN++N+I
Sbjct: 264 ------GNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNII 317
Query: 246 DFVAILPYFVALGTELARQRGVGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQ 303
DFVAILP+++ +G G+ +A L LRV+R VR+ RIFKL+RH GL++LG
Sbjct: 318 DFVAILPFYLEVGLS-----GLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGH 372
Query: 304 TLRASMRELGLLIFFLFIGVVLFSSAVYFAEV-------DRVDSH--FTSIPESFWWAVV 354
TLRAS E LLI FL +GV++F++ +Y+AE R + H F +IP FWWAVV
Sbjct: 373 TLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVV 432
Query: 355 TMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFY 401
TMTT+GYGDM P T G +VG+LCA+AGVLTI++PVPVIV+NF +Y
Sbjct: 433 TMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 261 bits (668), Expect = 7e-70
Identities = 181/467 (38%), Positives = 240/467 (51%), Gaps = 101/467 (21%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLG---DPARRGRFYDDARR------------EYF 57
E++++NV G R ET TL P T L DP GR D E+F
Sbjct: 36 EKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFF 95
Query: 58 FDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGL------------------- 98
FDRH F VL YY++G +L PA V +F EE+ F+G+
Sbjct: 96 FDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDA 154
Query: 99 ---------------GAA------------ALARLREDEGCPVPPERPLPRRAFARQLWL 131
GA AL RL EG R + ++W
Sbjct: 155 EEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWA 214
Query: 132 LFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLN 191
LFE P SS+AARV+A S+ ILVSI FCLET F DR+ T +
Sbjct: 215 LFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRV----------- 263
Query: 192 GSSQMPGNPPRLPFN-----DPFFV-VETLCICWFSFELLVRLLVCPSKAIFFKNVMNLI 245
GN + F +P +E +C+ WF+ E LVR++ CP F KN++N+I
Sbjct: 264 ------GNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNII 317
Query: 246 DFVAILPYFVALGTELARQRGVGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQ 303
DFVAILP+++ +G G+ +A L LRV+R VR+ RIFKL+RH GL++LG
Sbjct: 318 DFVAILPFYLEVGLS-----GLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGH 372
Query: 304 TLRASMRELGLLIFFLFIGVVLFSSAVYFAEV-------DRVDSH--FTSIPESFWWAVV 354
TLRAS E LLI FL +GV++F++ +Y+AE R + H F +IP FWWAVV
Sbjct: 373 TLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVV 432
Query: 355 TMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFY 401
TMTT+GYGDM P T G +VG+LCA+AGVLTI++PVPVIV+NF +Y
Sbjct: 433 TMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 261 bits (668), Expect = 7e-70
Identities = 181/467 (38%), Positives = 240/467 (51%), Gaps = 101/467 (21%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLG---DPARRGRFYDDARR------------EYF 57
E++++NV G R ET TL P T L DP GR D E+F
Sbjct: 36 EKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFF 95
Query: 58 FDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGL------------------- 98
FDRH F VL YY++G +L PA V +F EE+ F+G+
Sbjct: 96 FDRHPGVFAYVLNYYRTG-KLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDA 154
Query: 99 ---------------GAA------------ALARLREDEGCPVPPERPLPRRAFARQLWL 131
GA AL RL EG R + ++W
Sbjct: 155 EEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWA 214
Query: 132 LFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLN 191
LFE P SS+AARV+A S+ ILVSI FCLET F DR+ T +
Sbjct: 215 LFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRV----------- 263
Query: 192 GSSQMPGNPPRLPFN-----DPFFV-VETLCICWFSFELLVRLLVCPSKAIFFKNVMNLI 245
GN + F +P +E +C+ WF+ E LVR++ CP F KN++N+I
Sbjct: 264 ------GNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNII 317
Query: 246 DFVAILPYFVALGTELARQRGVGQQAMS--LAILRVIRLVRVFRIFKLSRHSKGLQILGQ 303
DFVAILP+++ +G G+ +A L LRV+R VR+ RIFKL+RH GL++LG
Sbjct: 318 DFVAILPFYLEVGLS-----GLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGH 372
Query: 304 TLRASMRELGLLIFFLFIGVVLFSSAVYFAEV-------DRVDSH--FTSIPESFWWAVV 354
TLRAS E LLI FL +GV++F++ +Y+AE R + H F +IP FWWAVV
Sbjct: 373 TLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVV 432
Query: 355 TMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFY 401
TMTT+GYGDM P T G +VG+LCA+AGVLTI++PVPVIV+NF +Y
Sbjct: 433 TMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 479
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 254 bits (648), Expect = 1e-67
Identities = 165/441 (37%), Positives = 243/441 (55%), Gaps = 60/441 (13%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLG--------DPARR-GRFYDDARREYFFDRHRP 63
E L +NV G+R + AR L RFP T LG + ARR YD+A RE++FDRH
Sbjct: 50 EALRVNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPG 109
Query: 64 SFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALA----------RLRE----D 109
F ++L++Y++G L + + F +E ++GLG ALA RL + D
Sbjct: 110 FFLSLLHFYRTG-HLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLTQPHAWD 168
Query: 110 EGCPVPP------------ERPLPRRAFAR------QLWLLFEFPESSQAARVLAVVSVL 151
E P +R L R AR +LWL E P S +++ + VS+
Sbjct: 169 EDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSIS 228
Query: 152 VILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFV 211
V+L SI C+ +LP+++ R+ AA AAG P + +DP
Sbjct: 229 VVLASIAAMCIHSLPEYQA-REAAAAVAAVAAGRSPEGVR--------------DDPVLR 273
Query: 212 -VETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQ 270
+E CI WFSFE+ RLL+ PS FF + +NLID V++LP+++ L +A G++
Sbjct: 274 RLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGKE 333
Query: 271 AMSLA-ILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSA 329
L +++V RL+R+FR+ KL+RHS GL+ LG TL+ S RE+G+L+ +L +GV +FS
Sbjct: 334 FGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGV 393
Query: 330 VYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLP 389
Y AE + D F +IP +WW V+MTTVGYGD+ PVTV GK+ S C + G+L ++LP
Sbjct: 394 AYTAEKEE-DVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALP 452
Query: 390 VPVIVSNFSYFYHRETEGEEA 410
+ +I + FS+FY R+ E A
Sbjct: 453 ITIIFNKFSHFYRRQKALEAA 473
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 251 bits (642), Expect = 7e-67
Identities = 180/494 (36%), Positives = 243/494 (49%), Gaps = 126/494 (25%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLL----------------GDP-------------- 42
ER++LNV G R ET TL P T L GD
Sbjct: 8 ERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRA 67
Query: 43 -------------------ARRGRFYDD--ARREYFFDRHRPSFDAVLYYYQSGGRLRRP 81
+R GR D RE+FFDRH F VL YY++G +L P
Sbjct: 68 PPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTG-KLHCP 126
Query: 82 AHVPLDVFLEEVAFYGLG-----------------------------------------A 100
A V +F EE+AF+G+ A
Sbjct: 127 ADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLA 186
Query: 101 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF 160
A + + G P + R ++W LFE P SS+AAR +A S+ ILVSI F
Sbjct: 187 AKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTF 246
Query: 161 CLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWF 220
CLET F ++ T +NG+S + + + VE +C+ WF
Sbjct: 247 CLETHEAFNIVKNKT-----------EPVINGTSVVLQY--EIETDPALTYVEGVCVVWF 293
Query: 221 SFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMS--LAILR 278
+FE LVR++ P+K F KN++N+IDFVAILP+++ +G G+ +A L LR
Sbjct: 294 TFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLS-----GLSSKAAKDVLGFLR 348
Query: 279 VIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRV 338
V+R VR+ RIFKL+RH GL++LG TLRAS E LLI FL +GV++F++ +Y+AE RV
Sbjct: 349 VVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAE--RV 406
Query: 339 DSH-----------FTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTIS 387
+ F +IP FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTI+
Sbjct: 407 GAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIA 466
Query: 388 LPVPVIVSNFSYFY 401
+PVPVIV+NF +Y
Sbjct: 467 MPVPVIVNNFGMYY 480
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 251 bits (642), Expect = 7e-67
Identities = 180/494 (36%), Positives = 243/494 (49%), Gaps = 126/494 (25%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLL----------------GDP-------------- 42
ER++LNV G R ET TL P T L GD
Sbjct: 8 ERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRA 67
Query: 43 -------------------ARRGRFYDD--ARREYFFDRHRPSFDAVLYYYQSGGRLRRP 81
+R GR D RE+FFDRH F VL YY++G +L P
Sbjct: 68 PPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTG-KLHCP 126
Query: 82 AHVPLDVFLEEVAFYGLG-----------------------------------------A 100
A V +F EE+AF+G+ A
Sbjct: 127 ADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLA 186
Query: 101 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF 160
A + + G P + R ++W LFE P SS+AAR +A S+ ILVSI F
Sbjct: 187 AKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTF 246
Query: 161 CLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWF 220
CLET F ++ T +NG+S + + + VE +C+ WF
Sbjct: 247 CLETHEAFNIVKNKT-----------EPVINGTSVVLQY--EIETDPALTYVEGVCVVWF 293
Query: 221 SFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMS--LAILR 278
+FE LVR++ P+K F KN++N+IDFVAILP+++ +G G+ +A L LR
Sbjct: 294 TFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLS-----GLSSKAAKDVLGFLR 348
Query: 279 VIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRV 338
V+R VR+ RIFKL+RH GL++LG TLRAS E LLI FL +GV++F++ +Y+AE RV
Sbjct: 349 VVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAE--RV 406
Query: 339 DSH-----------FTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTIS 387
+ F +IP FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTI+
Sbjct: 407 GAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIA 466
Query: 388 LPVPVIVSNFSYFY 401
+PVPVIV+NF +Y
Sbjct: 467 MPVPVIVNNFGMYY 480
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 251 bits (642), Expect = 7e-67
Identities = 180/494 (36%), Positives = 243/494 (49%), Gaps = 126/494 (25%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLL----------------GDP-------------- 42
ER++LNV G R ET TL P T L GD
Sbjct: 8 ERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRA 67
Query: 43 -------------------ARRGRFYDD--ARREYFFDRHRPSFDAVLYYYQSGGRLRRP 81
+R GR D RE+FFDRH F VL YY++G +L P
Sbjct: 68 PPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTG-KLHCP 126
Query: 82 AHVPLDVFLEEVAFYGLG-----------------------------------------A 100
A V +F EE+AF+G+ A
Sbjct: 127 ADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLA 186
Query: 101 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF 160
A + + G P + R ++W LFE P SS+AAR +A S+ ILVSI F
Sbjct: 187 AKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTF 246
Query: 161 CLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWF 220
CLET F ++ T +NG+S + + + VE +C+ WF
Sbjct: 247 CLETHEAFNIVKNKT-----------EPVINGTSVVLQY--EIETDPALTYVEGVCVVWF 293
Query: 221 SFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMS--LAILR 278
+FE LVR++ P+K F KN++N+IDFVAILP+++ +G G+ +A L LR
Sbjct: 294 TFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLS-----GLSSKAAKDVLGFLR 348
Query: 279 VIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRV 338
V+R VR+ RIFKL+RH GL++LG TLRAS E LLI FL +GV++F++ +Y+AE RV
Sbjct: 349 VVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAE--RV 406
Query: 339 DSH-----------FTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTIS 387
+ F +IP FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTI+
Sbjct: 407 GAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIA 466
Query: 388 LPVPVIVSNFSYFY 401
+PVPVIV+NF +Y
Sbjct: 467 MPVPVIVNNFGMYY 480
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 239 bits (609), Expect = 5e-63
Identities = 151/439 (34%), Positives = 228/439 (51%), Gaps = 78/439 (17%)
Query: 17 LNVAGLRFETRARTLGRFPDTLLGD----PARRGRF-----YDDARREYFFDRHRPSFDA 67
+NV G + R+ TL RFP+T LG +R YDD +RE++FDR+ F
Sbjct: 21 INVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPY 80
Query: 68 VLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARL--REDEGCPVPPERPL----- 120
VL++Y +G +L A + + F +E+ ++G+ + G V PE+
Sbjct: 81 VLHFYHTG-KLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQS 139
Query: 121 -------------------------PRRAFARQLWLLFEFPESSQAARVLAVVSVLVILV 155
P F RQLWL + P S +RV +++S+LV++
Sbjct: 140 DQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSILVVMG 199
Query: 156 SIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETL 215
SI+ CL +LPDF+ + S PG PR F +VE
Sbjct: 200 SIITMCLNSLPDFQ--------------------IPDSQGNPGEDPR------FEIVEHF 233
Query: 216 CICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLA 275
I WF+FEL+ R V P FFKN +NLID ++I+P+++ L L V + +LA
Sbjct: 234 GIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNL-----VVESTPTLA 288
Query: 276 ----ILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVY 331
+ +V+RL+R+FRI KL+RHS GL+ LG TL+ S +E+GLL+ +L +G+ +FS Y
Sbjct: 289 NLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAY 348
Query: 332 FAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVP 391
E + + +IP +WWA V+MTTVGYGD+ P T GK+ S C +AG+L + LP+
Sbjct: 349 TIEKEENEG-LATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPIT 407
Query: 392 VIVSNFSYFYHRETEGEEA 410
+I + FS+FY R+ + E A
Sbjct: 408 LIFNKFSHFYRRQKQLESA 426
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 238 bits (606), Expect = 1e-62
Identities = 134/296 (45%), Positives = 183/296 (61%), Gaps = 36/296 (12%)
Query: 123 RAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAA 182
R + ++W LFE P SS+AAR +A S+ IL+SI FCLET F + T
Sbjct: 270 RRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKT------- 322
Query: 183 AGPFPAPLNGSSQMPGNPPRLPFN-----DPFFV-VETLCICWFSFELLVRLLVCPSKAI 236
+ +S +PG PP N +PF VE +C+ WF+FE L+R+ CP K
Sbjct: 323 -------VTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVE 375
Query: 237 FFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMS--LAILRVIRLVRVFRIFKLSRH 294
F K+ +N+ID VAILP+++ +G G+ +A L LRV+R VR+ RIFKL+RH
Sbjct: 376 FLKSSLNIIDCVAILPFYLEVGLS-----GLSSKAAKDVLGFLRVVRFVRILRIFKLTRH 430
Query: 295 SKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVD---------SHFTSI 345
GL++LG TLRAS E LLI FL +GV++F++ +Y+AE D ++F +I
Sbjct: 431 FVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNI 490
Query: 346 PESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFY 401
P FWWAVVTMTT+GYGDM P T G +VG+LCA+AGVLTI++PVPVIV+NF +Y
Sbjct: 491 PIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY 546
Score = 61.2 bits (147), Expect = 2e-09
Identities = 38/89 (42%), Positives = 51/89 (57%), Gaps = 5/89 (5%)
Query: 14 RLVLNVAGLRFETRARTLGRFPDTLLG---DPARRGRF-YDDARREYFFDRHRPSFDAVL 69
++V+NV G+R ET TL P T L +P RF YD E+FFDRH F VL
Sbjct: 89 KIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVL 148
Query: 70 YYYQSGGRLRRPAHVPLDVFLEEVAFYGL 98
YY++G +L PA V +F EE+ F+G+
Sbjct: 149 NYYRTG-KLHCPADVCGPLFEEELGFWGI 176
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 224 bits (572), Expect = 1e-58
Identities = 148/426 (34%), Positives = 222/426 (52%), Gaps = 57/426 (13%)
Query: 15 LVLNVAGLRFETRARTLGRFP----DTLLGDPARRGRF-----YDDARREYFFDRHRPSF 65
+VLNV G R+ L FP L G + R YD R EYFFDRH +F
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 66 DAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALAR-------------------- 105
+L Y + G+LR + F E+ ++GL A L
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 106 ----LREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFC 161
L DE P E P R + ++ FE P SS AA++LA VSV+ ++VS+VV C
Sbjct: 131 EPGVLGRDEARPGGAEAA-PSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLC 189
Query: 162 LETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFS 221
TLPD+R+ AAA L+ S+ P R +P ++E +CI WF+
Sbjct: 190 ASTLPDWRN---------AAADN---RSLDDRSRYSAGPGR----EPSGIIEAICIGWFT 233
Query: 222 FELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVA-LGTELARQRGVGQQAMSLAILRVI 280
E +VR +V +K F K +N+ID +AI PY+++ L T + Q+A LRV+
Sbjct: 234 AECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAG--VTLRVL 291
Query: 281 RLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE----VD 336
R++R+F + KL+RH GLQ LG TL+ RE+ +L+ F+ + + +FS+ E ++
Sbjct: 292 RMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLE 351
Query: 337 RVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSN 396
+ FTSIP + WW +++MTTVGYGDM P+TV G+I+G +C ++G++ ++LP+ I +
Sbjct: 352 TSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHS 411
Query: 397 FSYFYH 402
F YH
Sbjct: 412 FVQCYH 417
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 217 bits (552), Expect = 2e-56
Identities = 144/426 (33%), Positives = 216/426 (50%), Gaps = 68/426 (15%)
Query: 15 LVLNVAGLRFETRARTLGRFP----DTLLGDPARRGRF-----YDDARREYFFDRHRPSF 65
+VLNV G R+ L FP L G + R YD R EYFFDRH +F
Sbjct: 11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAF 70
Query: 66 DAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALAR-------------------- 105
+L Y + G+LR + F E+ ++GL A L
Sbjct: 71 GFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSAD 130
Query: 106 ----LREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFC 161
L DE P E P R + ++ FE P SS AA++LA VSV+ ++VS+VV C
Sbjct: 131 EPGVLGRDEARPGGAEAA-PSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLC 189
Query: 162 LETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFS 221
TLPD+R+ AAA +D ++E +CI WF+
Sbjct: 190 ASTLPDWRN----------AAAD-----------------NRSLDDRSRIIEAICIGWFT 222
Query: 222 FELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVA-LGTELARQRGVGQQAMSLAILRVI 280
E +VR +V +K F K +N+ID +AI PY+++ L T + Q+A LRV+
Sbjct: 223 AECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAG--VTLRVL 280
Query: 281 RLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE----VD 336
R++R+F + KL+RH GLQ LG TL+ RE+ +L+ F+ + + +FS+ E ++
Sbjct: 281 RMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLE 340
Query: 337 RVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSN 396
+ FTSIP + WW +++MTTVGYGDM P+TV G+I+G +C ++G++ ++LP+ I +
Sbjct: 341 TSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHS 400
Query: 397 FSYFYH 402
F YH
Sbjct: 401 FVQCYH 406
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 214 bits (544), Expect = 2e-55
Identities = 136/436 (31%), Positives = 218/436 (50%), Gaps = 74/436 (16%)
Query: 13 ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRF---------YDDARREYFFDRHRP 63
E + LNV G + TL RFP T LG Y A +EY+FDR+
Sbjct: 15 ELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPS 74
Query: 64 SFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARL---REDEGCPVPPERPL 120
F VL +Y +G +L + + F +E+ ++G+ + R E E+
Sbjct: 75 LFRYVLNFYYTG-KLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDW 133
Query: 121 PRRA-----------------------------FARQLWLLFEFPESSQAARVLAVVSVL 151
+++ +++W+ E P +A+++A+ S+
Sbjct: 134 DQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLS 193
Query: 152 VILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFV 211
V+L SIV C+ ++ +F+++ DG +DP
Sbjct: 194 VVLASIVAMCVHSMSEFQNE-DGE-----------------------------VDDPVLE 223
Query: 212 -VETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQ 270
VE CI WF+ EL VRL P + F+KN +N+IDFV+I+P++ L + + +
Sbjct: 224 GVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIE 283
Query: 271 AMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAV 330
M +++++RL+R+FRI KL+RHS GL+ LG TLR S E+GLL+ FL +G+ +FS +
Sbjct: 284 NMG-KVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLI 342
Query: 331 YFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPV 390
Y E D S TSIP +WWA ++MTTVGYGD PVT+ GK++ S C I G+L ++LP+
Sbjct: 343 YSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPI 402
Query: 391 PVIVSNFSYFYHRETE 406
+I + FS +Y ++ +
Sbjct: 403 TIIFNKFSKYYQKQKD 418
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 211 bits (537), Expect = 1e-54
Identities = 151/462 (32%), Positives = 223/462 (48%), Gaps = 77/462 (16%)
Query: 1 MEPRCPPPCGCC-----ERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRF------- 48
+ P+ P GC R+++NV G+++ TL FP T LG F
Sbjct: 46 LRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVC 105
Query: 49 --YDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLG------- 99
YD E+FFDR+ +F +L + ++ G+LR + F EE+ ++G+
Sbjct: 106 DDYDVTCNEFFFDRNPGAFGTILTFLRA-GKLRLLREMCALSFQEELLYWGIAEDHLDGC 164
Query: 100 ------------AAALARLREDEGC---------PVPPERPLPRRAFARQLWLLFEFPES 138
A + R ED+ P E L R R+L + E P S
Sbjct: 165 CKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGR--CMRRLRDMVERPHS 222
Query: 139 SQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPG 198
+V A +SVL + V+ V + TLP R++ + SQM
Sbjct: 223 GLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEE----------------QGHCSQMCH 266
Query: 199 NPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALG 258
N F+VE++C+ WFS E L+RL+ PSK F ++ + LID VAILPY++ L
Sbjct: 267 N---------VFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLL 317
Query: 259 TELA----RQRGVGQQAMSLA--ILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMREL 312
+ A R+ G G + +LRV+R +R+ + +L+RHS GLQ LG T R RE
Sbjct: 318 VDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREF 377
Query: 313 GLLIFFLFIGVVLFSSAVYFAEVDRVDS-HFTSIPESFWWAVVTMTTVGYGDMAPVTVGG 371
GLL+ FL + + LF+ +Y E + DS FTSIP +WWAV+TMTTVGYGDM P + G
Sbjct: 378 GLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPG 437
Query: 372 KIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMF 413
++V ++G+L ++ PV I FS Y + +E MF
Sbjct: 438 QVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMF 479
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 210 bits (534), Expect = 2e-54
Identities = 152/471 (32%), Positives = 232/471 (49%), Gaps = 71/471 (15%)
Query: 15 LVLNVAGLRFETRARTLGRFPDTLLGDPAR--RGRF---------YDDARREYFFDRHRP 63
+V+NV G+R L ++P+T L + G + YD +RE++FDR
Sbjct: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 84
Query: 64 SFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLG----------------------AA 101
+F V+ Y G + P+ F E+ F+ + A
Sbjct: 85 AFKCVIEVYYFGEVHMKKGICPI-CFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIAR 143
Query: 102 ALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFC 161
+ + +D G R R + +W E PESS ARV+AV+S L+ILVS VV C
Sbjct: 144 RVQLILDDLGVDAAEGR---WRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMC 200
Query: 162 LETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFS 221
+ T+P+ + L A P N VET CI WF+
Sbjct: 201 MGTIPELQV------LDAEGNRVEHPTLEN--------------------VETACIGWFT 234
Query: 222 FELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIR 281
E L+RL P+K F + MN++D +AILP++V+L R + + A+ + +R
Sbjct: 235 LEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAV-QALR 293
Query: 282 LVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSH 341
++R+ RIFKL+RHS GLQ L L+ S +ELGLL+ +L +G+ +FS+ Y E ++
Sbjct: 294 IMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETL 353
Query: 342 FTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFY 401
F SIP+SFWWA++TMTTVGYGD+ P T GK+ ++ + GV+ I+LP+ I++NF +Y
Sbjct: 354 FKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYY 413
Query: 402 HRETEGEEAGM--FSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGK 450
+++ E A +++ EGK G D + LPP P GK
Sbjct: 414 NKQRVLETAAKHELELMELNSSSGGEGKTGGSRSD--LDNLPP---EPAGK 459
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.144 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,122,491
Number of Sequences: 37866
Number of extensions: 916370
Number of successful extensions: 4388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 153
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 3808
Number of HSP's gapped (non-prelim): 372
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.