Guide to the Human Genome
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Search of human proteins with 254039614

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo
sapiens]
         (618 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo s...  1262   0.0  
gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo sa...  1254   0.0  
gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo s...  1249   0.0  
gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo s...  1241   0.0  
gi|150010540 FERM domain containing 4B [Homo sapiens]                 140   5e-33
gi|116063562 FERM domain containing 4A [Homo sapiens]                 125   2e-28
gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens]    96   1e-19
gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens]    96   1e-19
gi|163965366 nascent polypeptide-associated complex alpha subuni...    75   2e-13
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    65   1e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    65   1e-10
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     61   3e-09
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          58   3e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          58   3e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          58   3e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    56   9e-08
gi|160707881 formin 2 [Homo sapiens]                                   55   2e-07
gi|145309324 FH2 domain containing 1 [Homo sapiens]                    54   3e-07
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    53   7e-07
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         52   1e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   2e-06
gi|40353727 synaptopodin isoform A [Homo sapiens]                      52   2e-06
gi|33286436 gametogenetin [Homo sapiens]                               51   3e-06
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    50   6e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         50   8e-06
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    49   1e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         49   1e-05
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    48   3e-05
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    47   5e-05
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     47   7e-05

>gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo
           sapiens]
          Length = 618

 Score = 1262 bits (3265), Expect = 0.0
 Identities = 618/618 (100%), Positives = 618/618 (100%)

Query: 1   MEVKAALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECP 60
           MEVKAALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECP
Sbjct: 1   MEVKAALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECP 60

Query: 61  LEPGERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRL 120
           LEPGERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRL
Sbjct: 61  LEPGERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRL 120

Query: 121 ALAPDLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITT 180
           ALAPDLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITT
Sbjct: 121 ALAPDLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITT 180

Query: 181 QGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV 240
           QGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV
Sbjct: 181 QGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV 240

Query: 241 SGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRG 300
           SGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRG
Sbjct: 241 SGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRG 300

Query: 301 AGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGG 360
           AGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGG
Sbjct: 301 AGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGG 360

Query: 361 GAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG 420
           GAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG
Sbjct: 361 GAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG 420

Query: 421 APRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVY 480
           APRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVY
Sbjct: 421 APRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVY 480

Query: 481 AADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHK 540
           AADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHK
Sbjct: 481 AADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHK 540

Query: 541 NLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPH 600
           NLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPH
Sbjct: 541 NLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPH 600

Query: 601 SRSFTAPPVSGRYGGCFY 618
           SRSFTAPPVSGRYGGCFY
Sbjct: 601 SRSFTAPPVSGRYGGCFY 618


>gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo
           sapiens]
          Length = 630

 Score = 1254 bits (3246), Expect = 0.0
 Identities = 614/614 (100%), Positives = 614/614 (100%)

Query: 5   AALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPG 64
           AALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPG
Sbjct: 17  AALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPG 76

Query: 65  ERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAP 124
           ERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAP
Sbjct: 77  ERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAP 136

Query: 125 DLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITTQGVC 184
           DLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITTQGVC
Sbjct: 137 DLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITTQGVC 196

Query: 185 LGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGS 244
           LGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGS
Sbjct: 197 LGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGS 256

Query: 245 PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQ 304
           PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQ
Sbjct: 257 PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQ 316

Query: 305 LCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGS 364
           LCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGS
Sbjct: 317 LCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGS 376

Query: 365 PPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRL 424
           PPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRL
Sbjct: 377 PPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRL 436

Query: 425 PPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADS 484
           PPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADS
Sbjct: 437 PPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADS 496

Query: 485 NSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHKNLAL 544
           NSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHKNLAL
Sbjct: 497 NSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHKNLAL 556

Query: 545 EGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPHSRSF 604
           EGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPHSRSF
Sbjct: 557 EGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPHSRSF 616

Query: 605 TAPPVSGRYGGCFY 618
           TAPPVSGRYGGCFY
Sbjct: 617 TAPPVSGRYGGCFY 630


>gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo
           sapiens]
          Length = 649

 Score = 1249 bits (3231), Expect = 0.0
 Identities = 613/613 (100%), Positives = 613/613 (100%)

Query: 1   MEVKAALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECP 60
           MEVKAALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECP
Sbjct: 1   MEVKAALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECP 60

Query: 61  LEPGERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRL 120
           LEPGERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRL
Sbjct: 61  LEPGERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRL 120

Query: 121 ALAPDLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITT 180
           ALAPDLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITT
Sbjct: 121 ALAPDLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITT 180

Query: 181 QGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV 240
           QGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV
Sbjct: 181 QGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV 240

Query: 241 SGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRG 300
           SGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRG
Sbjct: 241 SGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRG 300

Query: 301 AGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGG 360
           AGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGG
Sbjct: 301 AGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGG 360

Query: 361 GAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG 420
           GAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG
Sbjct: 361 GAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG 420

Query: 421 APRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVY 480
           APRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVY
Sbjct: 421 APRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVY 480

Query: 481 AADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHK 540
           AADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHK
Sbjct: 481 AADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHK 540

Query: 541 NLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPH 600
           NLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPH
Sbjct: 541 NLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPH 600

Query: 601 SRSFTAPPVSGRY 613
           SRSFTAPPVSGRY
Sbjct: 601 SRSFTAPPVSGRY 613


>gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 1241 bits (3212), Expect = 0.0
 Identities = 609/609 (100%), Positives = 609/609 (100%)

Query: 5   AALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPG 64
           AALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPG
Sbjct: 17  AALFGEAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPG 76

Query: 65  ERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAP 124
           ERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAP
Sbjct: 77  ERPQLVRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAP 136

Query: 125 DLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITTQGVC 184
           DLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITTQGVC
Sbjct: 137 DLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITTQGVC 196

Query: 185 LGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGS 244
           LGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGS
Sbjct: 197 LGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGS 256

Query: 245 PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQ 304
           PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQ
Sbjct: 257 PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQ 316

Query: 305 LCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGS 364
           LCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGS
Sbjct: 317 LCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGS 376

Query: 365 PPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRL 424
           PPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRL
Sbjct: 377 PPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRL 436

Query: 425 PPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADS 484
           PPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADS
Sbjct: 437 PPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADS 496

Query: 485 NSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHKNLAL 544
           NSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHKNLAL
Sbjct: 497 NSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHKNLAL 556

Query: 545 EGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPHSRSF 604
           EGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPHSRSF
Sbjct: 557 EGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPHSRSF 616

Query: 605 TAPPVSGRY 613
           TAPPVSGRY
Sbjct: 617 TAPPVSGRY 625


>gi|150010540 FERM domain containing 4B [Homo sapiens]
          Length = 1034

 Score =  140 bits (352), Expect = 5e-33
 Identities = 115/347 (33%), Positives = 180/347 (51%), Gaps = 41/347 (11%)

Query: 10  EAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQL 69
           E + + K E++  L  +++ LQE L  K++EL+K+CL+EAELTG++P E PL  GE+P  
Sbjct: 417 EVSEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQ 476

Query: 70  VRRRPPTARAYPPPHPNQAHHSLCPAEE-LALEALEREVSVQQQIAAAARRLALAPDLST 128
           VRRR  TA         +   +L P+EE  AL+ LE    +QQ++  AA++LA  PDL  
Sbjct: 477 VRRRVGTA--------FKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCK 528

Query: 129 EQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVITTQGVCLGMR 188
             +++R+Q   DA+++L E+E  + + R R G         LP                 
Sbjct: 529 TVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLP----------------- 571

Query: 189 LAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGSPERR 248
                 ED++  SESSSLS++  ++D+      F      S P +   L   S G  ER 
Sbjct: 572 ------EDII-PSESSSLSDT-TTYDDPSDAFTFPGQRSSSVPHSPRILPPKSLGI-ERI 622

Query: 249 TPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGA-GPQLCK 307
              K   ++ + D +  R  +++ +SP ++L R      GRS+P TPVLTR A      +
Sbjct: 623 HFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQG--GRSMPTTPVLTRNAYSSSHLE 680

Query: 308 PE--GLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEAL 352
           PE    H RQ SGS +SQ     ++  SD+    +++++RS+S+E L
Sbjct: 681 PESSSQHCRQRSGSLESQSHL-LSEMDSDKPFFSLSKSQRSSSTEIL 726


>gi|116063562 FERM domain containing 4A [Homo sapiens]
          Length = 1039

 Score =  125 bits (313), Expect = 2e-28
 Identities = 112/383 (29%), Positives = 167/383 (43%), Gaps = 56/383 (14%)

Query: 10  EAAPQVKSERLRGLLDRQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQL 69
           +++   K + L  L  RQ  L+E L  +L+EL+K+CL+EAELTG+LP E PL+PGE P +
Sbjct: 378 DSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPI 437

Query: 70  VRRRPPTARAYPPPHPNQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLSTE 129
           VRRR  TA              L   EE  LE LERE ++Q QI  AARRLA  P++S +
Sbjct: 438 VRRRIGTA------FKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKK 491

Query: 130 QRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVIT-----TQGVC 184
            +++R+    +AL++L E+E  + + R + G         L +  G++ +     +  + 
Sbjct: 492 LKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRAS-LIIDDGNIASEDSSLSDALV 550

Query: 185 LGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCF-----------SLAERPSPPKA 233
           L    +Q++     LHS    L     SH+   P                  + P  PK 
Sbjct: 551 LEDEDSQVTSTISPLHSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKM 610

Query: 234 WDQ------------LRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPR 281
           W +              + S  S  +R P     ++  G   S +N      SP R LP 
Sbjct: 611 WSESSLDEPYEKVKKRSSHSHSSSHKRFPSTGSCAEAGGGSNSLQN------SPIRGLPH 664

Query: 282 SASSFEGRSVPATPVL----------TRGA--GPQLCKPEGLHSRQWSGSQDSQMGFPRA 329
             S     S+P+TP L          TR     P       LH R  S S +SQ     +
Sbjct: 665 WNSQ---SSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGS 721

Query: 330 DPASDRASLFVARTRRSNSSEAL 352
           +  +     +  RTR SN S+ +
Sbjct: 722 ENDTGSPDFYTPRTRSSNGSDPM 744


>gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens]
          Length = 578

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 84/269 (31%), Positives = 125/269 (46%), Gaps = 41/269 (15%)

Query: 26  RQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPTARAYPPPHP 85
           +QR L+  L   L+ELR++CL+EAELTG LP E PL+PGE+   VRRR   A        
Sbjct: 37  QQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKL----D 92

Query: 86  NQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLSTEQRRRRRQVQADALRRL 145
           + A H      E  L +LER++++Q QI  AARRL L  +LS + RR+R+       ++L
Sbjct: 93  DWALH-----REDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKL 147

Query: 146 HELEEQLRDVRARLGLP---VLPLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSE 202
            EL+  L + R     P    LPL + L  S  S ++               + ++L  E
Sbjct: 148 QELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLS---------------DGLLLEEE 192

Query: 203 SSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV--SGGSPER----RTPWKPPPS 256
            S +         + P    +   RP PP+  + L+      GSPER     +PWK    
Sbjct: 193 ESQVP--------KPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 244

Query: 257 DLYGDLKSRRNSVASPTSPTRSLPRSASS 285
           D   +   + +   S +S   + P+   S
Sbjct: 245 DHPYEKPRKSSEPWSESSSPATTPQDGPS 273


>gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens]
          Length = 663

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 84/269 (31%), Positives = 125/269 (46%), Gaps = 41/269 (15%)

Query: 26  RQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPTARAYPPPHP 85
           +QR L+  L   L+ELR++CL+EAELTG LP E PL+PGE+   VRRR   A        
Sbjct: 122 QQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKL----D 177

Query: 86  NQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLSTEQRRRRRQVQADALRRL 145
           + A H      E  L +LER++++Q QI  AARRL L  +LS + RR+R+       ++L
Sbjct: 178 DWALH-----REDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKL 232

Query: 146 HELEEQLRDVRARLGLP---VLPLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSE 202
            EL+  L + R     P    LPL + L  S  S ++               + ++L  E
Sbjct: 233 QELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLS---------------DGLLLEEE 277

Query: 203 SSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV--SGGSPER----RTPWKPPPS 256
            S +         + P    +   RP PP+  + L+      GSPER     +PWK    
Sbjct: 278 ESQVP--------KPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329

Query: 257 DLYGDLKSRRNSVASPTSPTRSLPRSASS 285
           D   +   + +   S +S   + P+   S
Sbjct: 330 DHPYEKPRKSSEPWSESSSPATTPQDGPS 358


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 111/409 (27%), Positives = 145/409 (35%), Gaps = 64/409 (15%)

Query: 208  ESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGSPERRTPWKPP---PSDLYGDLKS 264
            +SGAS           LA+ PSP         VS     +R P K     P    G+L  
Sbjct: 774  DSGASATASSKGTLTYLADSPSP-------LGVSVSPQTKRPPTKKGSAGPDTPIGNL-- 824

Query: 265  RRNSVASPTSPTRS--LPRSASSFEG-RSVPAT-----PVLTRGAGPQLC----KPEG-- 310
                 +SP SP  +  LP ++ SF+G +  PAT     P   +GA          P+G  
Sbjct: 825  -----SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879

Query: 311  LHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGG--------GA 362
            L  ++        + FP+  PA+       A +  S+S +      A  G        GA
Sbjct: 880  LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA 939

Query: 363  GSPPAPLAPSASGPPVCKSSEVLYERPQPTP------AFSSRTAGPPDPPRAARPS---- 412
             +PPA   PS  G P   S +     P  TP        +    G P PP A  PS    
Sbjct: 940  PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG 999

Query: 413  SAAPASRGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTM 472
             A P+ +GAP  P V           +G P +         PPAA  P P  +     T 
Sbjct: 1000 PATPSPKGAPTPPAVTP------PSPKGSPAATPFPKGASTPPAATPPSP--KGSPAATP 1051

Query: 473  LP-GPPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIP 531
            LP G P   AA   SP      P  +   T P   PP    GP   P+P     PP   P
Sbjct: 1052 LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT-PSPKGAPMPPAATP 1110

Query: 532  SAGE----RSGHKNLALEGLRDWYIRNSGLAAGPQR-RPVLPSVGPPHP 575
             + +       HK               GLA  P +  P  P+  PP P
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 87/346 (25%), Positives = 117/346 (33%), Gaps = 60/346 (17%)

Query: 243  GSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAG 302
            GSP      K  P+     L S +   A+P+      P +A+    +  PATP       
Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM 1104

Query: 303  PQLCKPE----GLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAA 358
            P    P     GL +    G+  +    P A P S +  L     + + ++ A       
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTT----PAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160

Query: 359  GGGAGSPP--APLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAP 416
            GG A  PP  AP  P+A+ PP  K        P P  A ++  A PP P    +   A P
Sbjct: 1161 GGLATPPPKGAPTTPAAT-PPSPKGG---LATPSPKGAPTTPAATPPSP----KGGLATP 1212

Query: 417  ASRGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLP-G 475
            + +GAP                                PAA  P P   + GL T  P G
Sbjct: 1213 SPKGAP------------------------------TTPAATPPSP---KGGLATPSPKG 1239

Query: 476  PPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEG-----PEVHPNPLLWMPP-PTR 529
             P   AA   SP      P  +   T P   PP    G      +  PNP +  PP P  
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299

Query: 530  IPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHP 575
             P+     G              + S     P+  P  P+V PP P
Sbjct: 1300 GPATSPPKGAP--TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 81/352 (23%), Positives = 121/352 (34%), Gaps = 62/352 (17%)

Query: 229  SPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSP--TRSLPRSASSF 286
            SPPK      A +  SP + +P  PPP        +      +P SP  T +LP +  S 
Sbjct: 1304 SPPKGAPTPPAATPPSP-KGSPGTPPPKG------APTPPAVTPPSPKGTPTLPATTPSS 1356

Query: 287  EGRSVPATPVLTRGAGPQLCKPE---GLHSRQWSGSQDSQMGFPRADPASDRASLFVART 343
            +G   P TP    G  P    P    G      S  +   +  P+ DP S      +  +
Sbjct: 1357 KGG--PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV---IPLS 1411

Query: 344  RRSNSSEALLVDRAAGGGAG--SPPA------------------PLAPSASGPPVCKSSE 383
             +   +  +  + AA    G  +PPA                  P  PS+ G P   +  
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471

Query: 384  VLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSL---DRG 440
                +  P P   + ++ P   P       A PA  GAP LP V      +       R 
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAP-------ATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524

Query: 441  LPRSGGGTGWGE------------LPPAAEVPGPLSRRDGLLTMLPGPPPVYAADSNSPL 488
             P +   T   +            +PPA  VP P  +   + T    P    + +++SP 
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP-KKTPAIPTPKEAPATPSSKEASSPP 1583

Query: 489  LRTKDPHTRATRTKPCGLPPE-AAEGPEVHPNPLLWMPP-PTRIPSAGERSG 538
              T   +  A   K   +PP   +  P+  P P    PP P + P+     G
Sbjct: 1584 AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 77/326 (23%), Positives = 117/326 (35%), Gaps = 49/326 (15%)

Query: 225  AERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSAS 284
            A  P  PK     + V+  S  ++ P  P P      + +       P+SP + +P + S
Sbjct: 1469 AVTPPSPKEPPAPKQVATSSSPKKAPATPAP------MGAPTLPAVIPSSP-KEVPATPS 1521

Query: 285  SFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTR 344
            S      P   +L++     L   E L     +      +  P+  PA        A   
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMT------VPSPKKTPAIPTPKEAPATPS 1575

Query: 345  RSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPD 404
               +S    V  +   GA SP   L P A   P  K +        PTP        PP 
Sbjct: 1576 SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA--------PTPP----AVTPPS 1623

Query: 405  PPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAE----VP 460
            P +      A PA +G P  PPV    L D       P S        +P A++      
Sbjct: 1624 PEKGP----ATPAPKGTPTSPPVTPSSLKDSPTS---PASVTCKMGATVPQASKGLPAKK 1676

Query: 461  GPLSRRDGLLTMLPGPPPVYAADSNSPLLRTKDPHT-RATRTKPCGLPPEAA----EGP- 514
            GP + ++ L+   P   P+  A +       K P T +++ T P   P  +A    +GP 
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTR------KGPQTKKSSATSPPICPDPSAKNGSKGPL 1730

Query: 515  -EVHPNPLLWMPPPTRIPSAGERSGH 539
              V P PLL +   +   + G+ + H
Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASH 1756



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 79/347 (22%), Positives = 106/347 (30%), Gaps = 65/347 (18%)

Query: 249  TPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKP 308
            TP   PPS   G   +  +   +PT+P  + P         S    P       P     
Sbjct: 1174 TPAATPPSPKGG--LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS--PK 1229

Query: 309  EGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGG-------G 361
             GL +    G+  +    P A P S +        + + +  A       GG       G
Sbjct: 1230 GGLATPSPKGAPTT----PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG 1285

Query: 362  AGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPAS-RG 420
            A +P     PS  G P     +     P  TP     + G P P  A  P +  P S +G
Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345

Query: 421  APRLPPVCGDFLLDYSLDRGLPRSGGG-----TGWGELPPAA-------EVPGPLSRRDG 468
             P LP                P S GG     +  G  PPAA           P S + G
Sbjct: 1346 TPTLPAT-------------TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392

Query: 469  LLTMLPGPPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPT 528
                +P P     + +  PL   K P T  TR +    P +    P       L   P T
Sbjct: 1393 --PAIPSPKGDPTSPAVIPLSPKKAPATPVTR-EGAATPSKGDLTPPAVTPVSLKKAPAT 1449

Query: 529  RIPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHP 575
              P  G  +                        +  P LP+V PP P
Sbjct: 1450 SAPKGGPAT---------------------PSSKGDPTLPAVTPPSP 1475



 Score = 33.9 bits (76), Expect = 0.46
 Identities = 63/252 (25%), Positives = 89/252 (35%), Gaps = 31/252 (12%)

Query: 349 SEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRA 408
           S AL V  A G    + P P +P+   P  C  S      P P+P+  + T  P + P  
Sbjct: 29  SSALSVTAALGQPGPTLPPPCSPA---PQQCPLSAANQASPFPSPSTIAST--PLEVPFP 83

Query: 409 ARPSSAAPASRGAPR----LPPVCGDFLLDYSLDRGLPRSGG---GTGWGELPPAAEVPG 461
              S  A     AP     LP + G  +   +L    P       GT     P A     
Sbjct: 84  QSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALA 143

Query: 462 PLSRRDGLL---TMLPGPPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHP 518
           P S +        +L  PP V  A+S S +  +        +T    +P E    P+  P
Sbjct: 144 PHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTP 203

Query: 519 NP---LLWMPPPTRIPSAGERSGHKNL-----------ALEGLRDWYIRNSGLAAGPQRR 564
           +P   +  +P     P A  +SG  +L           A   ++D  I  S +   PQ  
Sbjct: 204 SPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTI--SSVLISPQNP 261

Query: 565 PVLPSVGPPHPP 576
             L   GP  PP
Sbjct: 262 GSLSLKGPVSPP 273


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 100/365 (27%), Positives = 136/365 (37%), Gaps = 46/365 (12%)

Query: 199 LHSESSSLSESGASHDNEEPHGCFSLAERP-SPPKAWDQLRAVS----GGSPERRTPWKP 253
           L S ++  ++SG S     P G  S + +P SPP    +    S     G PE +    P
Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170

Query: 254 PPSDLYGDLKSRRNSVASPTSPTRSLPRSA-SSFEGRSVPATPVLTRGAGPQLCKPE--G 310
           PP     D+ S+ +S+  P   T   PR   SS   R  P  P   R   P    P   G
Sbjct: 171 PPRP---DVGSKPDSIPPPVPST---PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG 224

Query: 311 LHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEAL----LVDRAAGGGAGSPP 366
                  G    Q     + P S+R  L    +R  +         + +R +      PP
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP 284

Query: 367 APLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG---APR 423
            P  P  + PPV  +         P P+ SS+   PP PP    P    P+S G    PR
Sbjct: 285 PP--PQNNKPPVPST---------PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPR 333

Query: 424 LPPVCGDFLLDYSLDRGLP--RSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYA 481
           LP        + SL    P   S G +G    PP+   P P+    G    LP PPPV  
Sbjct: 334 LPQ------RNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387

Query: 482 ADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPN-PLLWMPPPTRIPSAGERSGHK 540
             S S  L    P T    ++     P +   P + P+ P    PPP   PS   R+G +
Sbjct: 388 NGSTSRAL----PATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP-PSTSIRNGFQ 442

Query: 541 NLALE 545
           +   E
Sbjct: 443 DSPCE 447



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 54/198 (27%), Positives = 71/198 (35%), Gaps = 24/198 (12%)

Query: 245 PERRTPWKPPPSDLYGD----LKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRG 300
           P R  P   PPS    D    L  R  S++S T P  S         GRS P  P  +  
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS--------PGRSGPLPPPPSER 364

Query: 301 AGPQLCKPEGLHSRQWSGSQDSQMGFP-RADPASDRA-SLFVARTRRSNSSEALLVDRAA 358
             P +  P G           S+ G   RA PA+ +  S     + RS     L  DR +
Sbjct: 365 PPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPS 424

Query: 359 GGGAGSPPAPLAPSASG--PPVCKSS-------EVLYERPQPTPAFSSRTAGPPDPPRAA 409
            G A  PP P     +G     C+           + + P P P   +  + P    R  
Sbjct: 425 AG-APPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNE 483

Query: 410 RPSSAAPASRGAPRLPPV 427
             S +    RGAP LPP+
Sbjct: 484 SRSGSNRRERGAPPLPPI 501


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 100/365 (27%), Positives = 136/365 (37%), Gaps = 46/365 (12%)

Query: 199 LHSESSSLSESGASHDNEEPHGCFSLAERP-SPPKAWDQLRAVS----GGSPERRTPWKP 253
           L S ++  ++SG S     P G  S + +P SPP    +    S     G PE +    P
Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170

Query: 254 PPSDLYGDLKSRRNSVASPTSPTRSLPRSA-SSFEGRSVPATPVLTRGAGPQLCKPE--G 310
           PP     D+ S+ +S+  P   T   PR   SS   R  P  P   R   P    P   G
Sbjct: 171 PPRP---DVGSKPDSIPPPVPST---PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG 224

Query: 311 LHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEAL----LVDRAAGGGAGSPP 366
                  G    Q     + P S+R  L    +R  +         + +R +      PP
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP 284

Query: 367 APLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG---APR 423
            P  P  + PPV  +         P P+ SS+   PP PP    P    P+S G    PR
Sbjct: 285 PP--PQNNKPPVPST---------PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPR 333

Query: 424 LPPVCGDFLLDYSLDRGLP--RSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYA 481
           LP        + SL    P   S G +G    PP+   P P+    G    LP PPPV  
Sbjct: 334 LPQ------RNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSR 387

Query: 482 ADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPN-PLLWMPPPTRIPSAGERSGHK 540
             S S  L    P T    ++     P +   P + P+ P    PPP   PS   R+G +
Sbjct: 388 NGSTSRAL----PATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP-PSTSIRNGFQ 442

Query: 541 NLALE 545
           +   E
Sbjct: 443 DSPCE 447



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 54/198 (27%), Positives = 71/198 (35%), Gaps = 24/198 (12%)

Query: 245 PERRTPWKPPPSDLYGD----LKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRG 300
           P R  P   PPS    D    L  R  S++S T P  S         GRS P  P  +  
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS--------PGRSGPLPPPPSER 364

Query: 301 AGPQLCKPEGLHSRQWSGSQDSQMGFP-RADPASDRA-SLFVARTRRSNSSEALLVDRAA 358
             P +  P G           S+ G   RA PA+ +  S     + RS     L  DR +
Sbjct: 365 PPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPS 424

Query: 359 GGGAGSPPAPLAPSASG--PPVCKSS-------EVLYERPQPTPAFSSRTAGPPDPPRAA 409
            G A  PP P     +G     C+           + + P P P   +  + P    R  
Sbjct: 425 AG-APPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNE 483

Query: 410 RPSSAAPASRGAPRLPPV 427
             S +    RGAP LPP+
Sbjct: 484 SRSGSNRRERGAPPLPPI 501


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 80/317 (25%), Positives = 106/317 (33%), Gaps = 53/317 (16%)

Query: 228 PSPPKAWDQLRAVSGGS-----PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 282
           P PP    Q     GG+     P    P  PPP    GD KSR +S + P  P    P+ 
Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ---GDNKSR-SSRSPPGKPQGPPPQG 187

Query: 283 ASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVAR 342
            +  +G   P          PQ   P+G +  Q         G P   P  D        
Sbjct: 188 GNQPQGPPPPP-------GKPQGPPPQGGNKPQGPPPPGKPQGPP---PQGD-------- 229

Query: 343 TRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQ-PTPAFSSRTAG 401
               N S++    R+  G    PP        GPP          +PQ P P   ++  G
Sbjct: 230 ----NKSQSA---RSPPGKPQGPPPQGGNQPQGPPPPPG------KPQGPPPQGGNKPQG 276

Query: 402 PPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPG 461
           PP P +   P     +   + R PP            +G P  GG    G  PP  +  G
Sbjct: 277 PPPPGKPQGPPPQGGSKSRSSRSPP---------GKPQGPPPQGGNQPQGPPPPPGKPQG 327

Query: 462 PLSRRDGLLTMLPGPPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPL 521
           P  +         GPPP        P   +K    R+   KP G P +    P+  P P 
Sbjct: 328 PPPQGGN---KPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPA 384

Query: 522 LWMPPPTRIPSAGERSG 538
              P   + P AG+  G
Sbjct: 385 GGNPQQPQAPPAGQPQG 401



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 50/186 (26%), Positives = 66/186 (35%), Gaps = 23/186 (12%)

Query: 361 GAGSPPAPLAPSAS--GPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPAS 418
           G   P  P +P     GPP    ++     PQ  P    +  GPP P    +P    P  
Sbjct: 43  GGNKPQGPPSPPGKPQGPPPQGGNQ-----PQGPPPPPGKPQGPP-PQGGNKPQGPPPP- 95

Query: 419 RGAPRLPPVCGDFLLD----YSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLP 474
            G P+ PP  GD            +G P  GG    G  PP  +  GP  +         
Sbjct: 96  -GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG---NKPQ 151

Query: 475 GPPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAG 534
           GPPP        P    K   +R+   KP G PP+    P+  P      PPP +     
Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP------PPPGKPQGPP 205

Query: 535 ERSGHK 540
            + G+K
Sbjct: 206 PQGGNK 211



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 53/191 (27%), Positives = 71/191 (37%), Gaps = 40/191 (20%)

Query: 228 PSPPKAWDQLRAVSGGS-----PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 282
           P PP    Q     GG+     P    P  PPP    G  KSR +S + P  P    P+ 
Sbjct: 256 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ---GGSKSR-SSRSPPGKPQGPPPQG 311

Query: 283 ASSFEGRSVPATPVLTRGAGPQLC-KPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVA 341
            +  +G   P  P   +G  PQ   KP+G              G P+  P    +    +
Sbjct: 312 GNQPQGP--PPPPGKPQGPPPQGGNKPQG----------PPPPGKPQGPPPQGGSK---S 356

Query: 342 RTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAG 401
           R+ RS   +     +  G     PP P    A G P         ++PQ  PA   +  G
Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQGPPPP----AGGNP---------QQPQAPPA--GQPQG 401

Query: 402 PPDPPRAARPS 412
           PP PP+  RPS
Sbjct: 402 PPRPPQGGRPS 412



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 63/249 (25%), Positives = 86/249 (34%), Gaps = 54/249 (21%)

Query: 228 PSPPKAWDQLRAVSGGS-----PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 282
           P PP    Q     GG+     P    P  PPP    GD KS+  S  SP    +  P  
Sbjct: 194 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ---GDNKSQ--SARSPPGKPQGPPP- 247

Query: 283 ASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVAR 342
               +G + P  P    G  PQ   P+G +  Q         G P    +  R+S     
Sbjct: 248 ----QGGNQPQGPPPPPGK-PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS----- 297

Query: 343 TRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQ-PTPAFSSRTAG 401
                        R+  G    PP        GPP          +PQ P P   ++  G
Sbjct: 298 -------------RSPPGKPQGPPPQGGNQPQGPPPPPG------KPQGPPPQGGNKPQG 338

Query: 402 PPDP-------PRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPR-SGGGTGWGEL 453
           PP P       P+    S +A +  G P+ PP       + +  +G P  +GG     + 
Sbjct: 339 PPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQ-----QEGNNPQGPPPPAGGNPQQPQA 393

Query: 454 PPAAEVPGP 462
           PPA +  GP
Sbjct: 394 PPAGQPQGP 402



 Score = 37.4 bits (85), Expect = 0.041
 Identities = 40/162 (24%), Positives = 54/162 (33%), Gaps = 40/162 (24%)

Query: 380 KSSEVLYERPQPTPAFS-SRTAGPPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLD 438
           +S  ++   PQ  P    ++  GPP PP   +P    P     P+ PP            
Sbjct: 27  ESPSLIAGNPQGAPPQGGNKPQGPPSPP--GKPQGPPPQGGNQPQGPPP------PPGKP 78

Query: 439 RGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADSNSPLLRTKDPHTRA 498
           +G P  GG    G  PP                  P  PP     S SP         R+
Sbjct: 79  QGPPPQGGNKPQGPPPPGK----------------PQGPPPQGDKSRSP---------RS 113

Query: 499 TRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHK 540
              KP G PP+    P+  P      PPP +      + G+K
Sbjct: 114 PPGKPQGPPPQGGNQPQGPP------PPPGKPQGPPPQGGNK 149


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 95/390 (24%), Positives = 137/390 (35%), Gaps = 66/390 (16%)

Query: 256 SDLYGDLKSRRNSVASPTSPTRSLPRSASSF----EGRSVPAT-PVLTRGAGPQLCKPEG 310
           +D     K++   ++ P SP+     S+ S     EG S P       R   P +  P+ 
Sbjct: 107 ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD 166

Query: 311 LHSRQWSGSQDSQMGFPRADPASDRASLFV--ARTRRSNSSEALLVDRAAGGGAGSPP-- 366
             S   S +Q   +   +A P + +A   V  A +     +  L            PP  
Sbjct: 167 NESDSDSSAQQQML---QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG 223

Query: 367 APLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPP 426
           +P A  A   P   ++ V +   Q  PA   +    P PP    P          P L P
Sbjct: 224 SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH---------PPLQP 274

Query: 427 VCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPP-----PVYA 481
           + G      +     P        G+ PP     GP S + G L   PGPP     P  A
Sbjct: 275 LTGS-----AGQPSAPSHAQPPLHGQGPP-----GPHSLQAGPLLQHPGPPQPFGLPPQA 324

Query: 482 ADSNSPLLRTKD---PHT--------------RATRTKPCGLPPEAAEGPEVHPNPLLWM 524
           +   +PL  +     PHT              +  R +P  LPP     P + P      
Sbjct: 325 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP--LPPAPLAMPHIKP------ 376

Query: 525 PPPTRIPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYE 584
           PP T IP       HK+         +  N+ L   P  +P L S+   HPP  H    +
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP-LSSLSTHHPPSAHPPPLQ 435

Query: 585 V---GQALYGAPSQAP-LPHSRSFTAPPVS 610
           +    Q L  +P+Q P L  S++   PP S
Sbjct: 436 LMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 465


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 95/390 (24%), Positives = 137/390 (35%), Gaps = 66/390 (16%)

Query: 256  SDLYGDLKSRRNSVASPTSPTRSLPRSASSF----EGRSVPAT-PVLTRGAGPQLCKPEG 310
            +D     K++   ++ P SP+     S+ S     EG S P       R   P +  P+ 
Sbjct: 661  ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD 720

Query: 311  LHSRQWSGSQDSQMGFPRADPASDRASLFV--ARTRRSNSSEALLVDRAAGGGAGSPP-- 366
              S   S +Q   +   +A P + +A   V  A +     +  L            PP  
Sbjct: 721  NESDSDSSAQQQML---QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG 777

Query: 367  APLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPP 426
            +P A  A   P   ++ V +   Q  PA   +    P PP    P          P L P
Sbjct: 778  SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH---------PPLQP 828

Query: 427  VCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPP-----PVYA 481
            + G      +     P        G+ PP     GP S + G L   PGPP     P  A
Sbjct: 829  LTGS-----AGQPSAPSHAQPPLHGQGPP-----GPHSLQAGPLLQHPGPPQPFGLPPQA 878

Query: 482  ADSNSPLLRTKD---PHT--------------RATRTKPCGLPPEAAEGPEVHPNPLLWM 524
            +   +PL  +     PHT              +  R +P  LPP     P + P      
Sbjct: 879  SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP--LPPAPLAMPHIKP------ 930

Query: 525  PPPTRIPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYE 584
            PP T IP       HK+         +  N+ L   P  +P L S+   HPP  H    +
Sbjct: 931  PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP-LSSLSTHHPPSAHPPPLQ 989

Query: 585  V---GQALYGAPSQAP-LPHSRSFTAPPVS 610
            +    Q L  +P+Q P L  S++   PP S
Sbjct: 990  LMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 95/390 (24%), Positives = 137/390 (35%), Gaps = 66/390 (16%)

Query: 256  SDLYGDLKSRRNSVASPTSPTRSLPRSASSF----EGRSVPAT-PVLTRGAGPQLCKPEG 310
            +D     K++   ++ P SP+     S+ S     EG S P       R   P +  P+ 
Sbjct: 661  ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD 720

Query: 311  LHSRQWSGSQDSQMGFPRADPASDRASLFV--ARTRRSNSSEALLVDRAAGGGAGSPP-- 366
              S   S +Q   +   +A P + +A   V  A +     +  L            PP  
Sbjct: 721  NESDSDSSAQQQML---QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG 777

Query: 367  APLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPP 426
            +P A  A   P   ++ V +   Q  PA   +    P PP    P          P L P
Sbjct: 778  SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH---------PPLQP 828

Query: 427  VCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPP-----PVYA 481
            + G      +     P        G+ PP     GP S + G L   PGPP     P  A
Sbjct: 829  LTGS-----AGQPSAPSHAQPPLHGQGPP-----GPHSLQAGPLLQHPGPPQPFGLPPQA 878

Query: 482  ADSNSPLLRTKD---PHT--------------RATRTKPCGLPPEAAEGPEVHPNPLLWM 524
            +   +PL  +     PHT              +  R +P  LPP     P + P      
Sbjct: 879  SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP--LPPAPLAMPHIKP------ 930

Query: 525  PPPTRIPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYE 584
            PP T IP       HK+         +  N+ L   P  +P L S+   HPP  H    +
Sbjct: 931  PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP-LSSLSTHHPPSAHPPPLQ 989

Query: 585  V---GQALYGAPSQAP-LPHSRSFTAPPVS 610
            +    Q L  +P+Q P L  S++   PP S
Sbjct: 990  LMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 90/373 (24%), Positives = 125/373 (33%), Gaps = 60/373 (16%)

Query: 226 ERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVA-------SPTSPTRS 278
           +RP PP     L  V  G        +PPP    G       + A       +P  P + 
Sbjct: 103 QRPGPPSPRRPL--VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK- 159

Query: 279 LPRSASSFEGRSVPAT-PVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRAS 337
            P   ++   R+ P   P    G GP   KP G  + Q      + +    A  A+   S
Sbjct: 160 -PAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHA--AAPAVS 216

Query: 338 LFVARTRRSNSSEALLV--DRAAGG---------GAGSPPAPLAPSASGPPVCKSSEVLY 386
           L       +N   ALL     AA G         GA +PPAP APS    P   +     
Sbjct: 217 LV------NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP 270

Query: 387 ERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPRSGG 446
             P P PA  +R  G P  P  A P+   PA+                        ++GG
Sbjct: 271 PPPPPAPATLARPPGHPAGPPTAAPAVPPPAA-----------------------AQNGG 307

Query: 447 GTGWGELP-PAAEVPGPLSRRDGLLTMLPGPPPVYAADSNSPLLRTKDPHTRATRTKPCG 505
             G    P PAA  P  +S + G       P P   A+S   +++   P   A +T    
Sbjct: 308 SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPP---AAQTLAAS 364

Query: 506 LPPEAAEGPEVHPNPLLWMPPPTRI--PSAGERSGHKNLALEGLRDWYIRNSGLAAGPQR 563
            P   A    + P     +P P  +  P+ G  +G    A   +     R         R
Sbjct: 365 GPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIR 424

Query: 564 RPVLPSVGPPHPP 576
             + P+V  P  P
Sbjct: 425 ATLTPTVLAPRLP 437



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 72/261 (27%), Positives = 88/261 (33%), Gaps = 63/261 (24%)

Query: 359 GGGAGSPPA------PLAPSASGPPVCK---SSEVLYERPQPTPAFSSRTAGP-PDPPRA 408
           GGG    P       PL P+   PP  K     E       P PA ++  AGP P P   
Sbjct: 98  GGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGP 157

Query: 409 ARPSS-AAPASRGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRD 467
           A+P+  AA A+R  P   P  G            P  G G G    P AA+    L+   
Sbjct: 158 AKPAGPAALAARAGPGPGPGPG------------PGPGPGPGKPAGPGAAQT---LNGSA 202

Query: 468 GLLTMLPGPPPVYAADSNSP--LLRTKDPHTRAT--RTKP----CGLPPEAAEGPEVHP- 518
            LL       P  +  +N P  LL    P    T  +T P       P  AA  P   P 
Sbjct: 203 ALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA 262

Query: 519 --NPLLWMPPPTRIPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPP 576
              P    PPP   P+                    R  G  AGP      P+  P  PP
Sbjct: 263 PAAPAAAPPPPPPAPAT-----------------LARPPGHPAGP------PTAAPAVPP 299

Query: 577 FLHARCYEVGQALYGAPSQAP 597
              A   + G +   AP+ AP
Sbjct: 300 PAAA---QNGGSAGAAPAPAP 317


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 73/251 (29%), Positives = 85/251 (33%), Gaps = 52/251 (20%)

Query: 361  GAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG 420
            GAG PP P  P A  PP           P P P   +    PP  P A  P        G
Sbjct: 1016 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAG 1073

Query: 421  APRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVY 480
             P  PP+ G          G+P      G G +PP   +PG           +P PPP+ 
Sbjct: 1074 IPPPPPLPG---------AGIPPPPPLPGAG-IPPPPPLPG---------VGIPPPPPLP 1114

Query: 481  AADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHK 540
             A    P      P   A    P  LP   A  P   P P + +PPP  +P AG      
Sbjct: 1115 GAGIPPP-----PPLPGAGIPPPPPLP--GAGIPPPPPLPRVGIPPPPPLPGAGIPPPP- 1166

Query: 541  NLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPH 600
               L G            AG    P LP VG P PP L            G P   PLP 
Sbjct: 1167 --PLPG------------AGIPPPPPLPGVGIPPPPPLPG---------VGIPPPPPLPG 1203

Query: 601  SRSFTAPPVSG 611
            +     PP+ G
Sbjct: 1204 AGIPPPPPLPG 1214



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 71/255 (27%), Positives = 86/255 (33%), Gaps = 57/255 (22%)

Query: 359  GGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPAS 418
            G G   PP P  P  + P +  ++      PQP P   +    PP PP            
Sbjct: 872  GLGMVPPPPPPLPGMTVPTLPSTAI-----PQPPPLQGTEMLPPPPPPL---------PG 917

Query: 419  RGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPP 478
             G P  PP+ G  +L        P  G G     +PP   +PG           +P PPP
Sbjct: 918  AGIPPPPPLPGAGILPLP-----PLPGAG-----IPPPPPLPG---------AAIPPPPP 958

Query: 479  VYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSG 538
            +  A    P      P   A    P  LP   A  P   P P   +PPP  +P AG    
Sbjct: 959  LPGAGIPLP-----PPLPGAGIPPPPPLP--GAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011

Query: 539  HKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGA--PSQA 596
                 L G            AG    P LP  G P PP L          L GA  P   
Sbjct: 1012 P---PLPG------------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1056

Query: 597  PLPHSRSFTAPPVSG 611
            PLP +     PP+ G
Sbjct: 1057 PLPGAGIPPPPPLPG 1071



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 74/264 (28%), Positives = 88/264 (33%), Gaps = 60/264 (22%)

Query: 361  GAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG 420
            GAG PP P  P A  PP             P P   +    PP  P A  P        G
Sbjct: 1060 GAGIPPPPPLPGAGIPP-------------PPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1106

Query: 421  APRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPG-------PLSRRDGLLTML 473
             P  PP+ G          G+P      G G +PP   +PG       PL R       +
Sbjct: 1107 IPPPPPLPG---------AGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPR-----VGI 1151

Query: 474  PGPPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSA 533
            P PPP+  A    P      P   A    P  LP      P   P P + +PPP  +P A
Sbjct: 1152 PPPPPLPGAGIPPP-----PPLPGAGIPPPPPLPGVGIPPPP--PLPGVGIPPPPPLPGA 1204

Query: 534  GERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYG-- 591
            G         L G+        G+   P      P  G P PP L       G  L    
Sbjct: 1205 GIPPPP---PLPGM--------GIPPAPAPPLPPPGTGIPPPPLLPVS----GPPLLPQV 1249

Query: 592  APSQAPLPHSRSFTAPPV-SGRYG 614
              S  P P    F  PP+ SG +G
Sbjct: 1250 GSSTLPTPQVCGFLPPPLPSGLFG 1273



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 47/201 (23%), Positives = 67/201 (33%), Gaps = 16/201 (7%)

Query: 206 LSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSR 265
           + E       EEP      A+ P  P A     ++ G     +  +KP P      +K+ 
Sbjct: 370 VGEDAPQRLGEEPE---EEAQGPDAPAA----ASLPGSPAPSQRCFKPYPLITPCYIKTT 422

Query: 266 RNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMG 325
              ++SP       P  +   + R  P+    +R A   +  P   H      +     G
Sbjct: 423 TRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAA----G 478

Query: 326 FPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKS--SE 383
             R+   +D      ART R   S  LL    A    G     LA  ASG P        
Sbjct: 479 LSRS---ADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQN 535

Query: 384 VLYERPQPTPAFSSRTAGPPD 404
           V   R      FS +  GPP+
Sbjct: 536 VFTGRTLLEKLFSQQENGPPE 556


>gi|145309324 FH2 domain containing 1 [Homo sapiens]
          Length = 1143

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 83/350 (23%), Positives = 126/350 (36%), Gaps = 47/350 (13%)

Query: 201  SESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGSP-ERRTPWKPPPSDLY 259
            S SS + E G S  +  P       E P+P    D   +  GG P ++ T  K   +   
Sbjct: 807  SMSSGVGEMGDSQVSSNPTSS-PPGEAPAPVSV-DSEPSCKGGLPRDKPTKRKDVVAPKR 864

Query: 260  GDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCK----PEGLHSRQ 315
            G LK          SP  S P SA   +G    +   LT      + K     +      
Sbjct: 865  GSLKE--------ASPGASKPGSARRSQGAVAKSVRTLTASENESMRKVMPITKSSRGAG 916

Query: 316  WSGSQDSQMGFPRADPASDRASLFVART---RRSNSSEALLVDRAAGGGAGSPPA---PL 369
            W   + S  G P  +P S   +++  +    R S  +E   + R + G + + P    PL
Sbjct: 917  WRRPELSSRG-PSQNPPSSTDTVWSRQNSVRRASTGAEEQRLPRGSSGSSSTRPGRDVPL 975

Query: 370  APSAS--GPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPPV 427
             P  S   P       +  ++P+      + + GP  P    +  S        PR+P  
Sbjct: 976  QPRGSFKKPSAKPLRNLPRQKPEENKTCRAHSEGPESPKEEPKTPSVPSVPHELPRVP-- 1033

Query: 428  CGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADSNSP 487
                    S  R    S   +   +LPP A+ PG ++R      +     P  AA  +S 
Sbjct: 1034 --------SFARNTVASSSRSMRTDLPPVAKAPG-ITRTVSQRQLRVKGDPEDAAPKDSS 1084

Query: 488  LLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERS 537
             LR      RA+  +     PE+AEGP  +         P +   AGER+
Sbjct: 1085 TLR------RASSARAPKKRPESAEGPSANTE------APLKARGAGERA 1122


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 87/360 (24%), Positives = 116/360 (32%), Gaps = 60/360 (16%)

Query: 185 LGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGS 244
           L +  AQ   EDV   S+  S S    +     P G  +  + P PP    Q     GG+
Sbjct: 11  LALSSAQNLNEDV---SQEESPSLIAGNPQGPSPQGG-NKPQGPPPPPGKPQGPPPQGGN 66

Query: 245 -----PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTR 299
                P    P  PPP    GD    R+  + P  P    P+  +  +G   P       
Sbjct: 67  KPQGPPPPGKPQGPPPQ---GD--KSRSPRSPPGKPQGPPPQGGNQPQGPPPPP------ 115

Query: 300 GAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAG 359
              PQ   P+G +  Q         G P   P  D++        RS         R+  
Sbjct: 116 -GKPQGPPPQGGNRPQGPPPPGKPQGPP---PQGDKS--------RS--------PRSPP 155

Query: 360 GGAGSPPAPLAPSASGPPVCKSSEVLYERPQ-PTPAFSSRTAGPPDPPRAARPSSAAPAS 418
           G    PP        GPP          +PQ P P    +  GPP P +   P      S
Sbjct: 156 GKPQGPPPQGGNQPQGPPPPPG------KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKS 209

Query: 419 RGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPP 478
           R +   P             +G P  GG    G  PP  +  GP  +         GPPP
Sbjct: 210 RSSQSPP----------GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN---KPQGPPP 256

Query: 479 VYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSG 538
                       +K    R+   KP G P +    P+  P P    P   + P AG+  G
Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 316



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 52/191 (27%), Positives = 70/191 (36%), Gaps = 41/191 (21%)

Query: 228 PSPPKAWDQLRAVSGGS-----PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 282
           P PP    Q     GG      P    P  PPP    GD    R+S + P  P    P+ 
Sbjct: 172 PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ---GD--KSRSSQSPPGKPQGPPPQG 226

Query: 283 ASSFEGRSVPATPVLTRGAGPQLC-KPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVA 341
            +  +G   P  P   +G  PQ   KP+G              G P+  PA   +    +
Sbjct: 227 GNQPQGP--PPPPGKPQGPPPQGGNKPQG----------PPPPGKPQGPPAQGGSK---S 271

Query: 342 RTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAG 401
           ++ RS   +     +  G     PP P    A G P         ++PQ  PA   +  G
Sbjct: 272 QSARSPPGKPQGPPQQEGNNPQGPPPP----AGGNP---------QQPQAPPA--GQPQG 316

Query: 402 PPDPPRAARPS 412
           PP PP+  RPS
Sbjct: 317 PPRPPQGGRPS 327



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 59/244 (24%), Positives = 82/244 (33%), Gaps = 46/244 (18%)

Query: 228 PSPPKAWDQLRAVSGGS-----PERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 282
           P PP    Q     GG+     P    P  PPP    GD    R+  + P  P    P+ 
Sbjct: 111 PPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQ---GD--KSRSPRSPPGKPQGPPPQG 165

Query: 283 ASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVAR 342
            +  +G   P          PQ   P+G    Q         G P   P  D++      
Sbjct: 166 GNQPQGPPPPP-------GKPQGPPPQGGKKPQGPPPPGKPQGPP---PQGDKS------ 209

Query: 343 TRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQ-PTPAFSSRTAG 401
             RS+ S          G    PP        GPP          +PQ P P   ++  G
Sbjct: 210 --RSSQSPP--------GKPQGPPPQGGNQPQGPPPPPG------KPQGPPPQGGNKPQG 253

Query: 402 PPDPPRAARPSSAAPASRGAPRLPP--VCGDFLLDYSLDRGLPR-SGGGTGWGELPPAAE 458
           PP P +   P +   +   + R PP    G    + +  +G P  +GG     + PPA +
Sbjct: 254 PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 313

Query: 459 VPGP 462
             GP
Sbjct: 314 PQGP 317



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 18/66 (27%), Positives = 22/66 (33%)

Query: 361 GAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRG 420
           G   P  P  P A G    +S+     +PQ  P         P PP    P        G
Sbjct: 253 GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG 312

Query: 421 APRLPP 426
            P+ PP
Sbjct: 313 QPQGPP 318


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 92/334 (27%), Positives = 119/334 (35%), Gaps = 73/334 (21%)

Query: 253 PPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLH 312
           PPPSDL     +  +++ +   P  +L  +A   EG +         GAG       G  
Sbjct: 605 PPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSA--------EGAG-------GPS 649

Query: 313 SRQWSGSQD-SQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAP 371
              +SG  D S + FP   P S   +L    +         L+       +G+PP P   
Sbjct: 650 GEPFSGLGDLSPLLFP---PLSAPPTLIALNSA--------LLAATLDPPSGTPPQPCVL 698

Query: 372 SASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAP--RLPPVCG 429
           SA               PQP P  SS T    DP   A     AP++ G P   L P+ G
Sbjct: 699 SA---------------PQPGPPTSSVTTATTDP--GASSLGKAPSNSGRPPQLLSPLLG 741

Query: 430 DFLL-DYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPG---PPPVYAADSN 485
             LL D S     P        G LP   + PGPL      L +LPG   PPP+  A S 
Sbjct: 742 ASLLGDLSSLTSSP--------GALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSP 793

Query: 486 SPLLRTKDPHTRATRTKPCGLPPE---AAEGPEVHPNPLLWMPPPTRIP----------- 531
              L             PC LPPE   +A  PE    PL  + PP   P           
Sbjct: 794 LACLLQSLQIPPEQPEAPC-LPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGR 852

Query: 532 SAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRP 565
            +G+R       L G+        G   G +R P
Sbjct: 853 GSGKRGRRGGGGLRGINGEARPARGRKPGSRREP 886



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 106/395 (26%), Positives = 140/395 (35%), Gaps = 63/395 (15%)

Query: 250 PWKPPPSDLYGDLKSRRNSVASPTS---PTRSLPRSASS----FEGRSVPATPVLTRGAG 302
           P  PPPS L G     +   AS +S   P++  PR   +     EGR  P TP  +R   
Sbjct: 333 PPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRG-PQTPRRSRPRA 391

Query: 303 PQ-LCKPEGLH--SRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAG 359
           P  + +P  L   S+    S  S +G P   P+    S  +  +         L      
Sbjct: 392 PAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTL------ 445

Query: 360 GGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASR 419
             +GSPP P  P     P   S  +      P P  +S+    P P   +        + 
Sbjct: 446 -SSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAG 504

Query: 420 GAPRLPPVCGDFLLDY-SLDRGLPRSGGGTG--WGELPPAAEV----PGPLSRRD--GLL 470
            A  LPP+ G     + S ++GL  SG G     G LP    +    P PL      G+L
Sbjct: 505 PACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVL 564

Query: 471 TMLPGPPPVYAADSNSPLLRTKDPHTRATRTKPCG----LPPEAAEGPE------VHPNP 520
           T   G PP        PLL             P G    L P   EGP       + P P
Sbjct: 565 TGGGGQPP------PEPLL-----------PPPGGPGPPLAPGEPEGPSLLVASLLPPPP 607

Query: 521 LLWMPPPTRIPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRP------VLPSVGPP- 573
              +PPP+  PS    S    LAL         ++  A GP   P      + P + PP 
Sbjct: 608 SDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPL 667

Query: 574 -HPPFLHARCYEVGQALYGAPSQAPLPHSRSFTAP 607
             PP L A    +  A    PS  P P     +AP
Sbjct: 668 SAPPTLIALNSALLAATLDPPSGTP-PQPCVLSAP 701



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 66/260 (25%), Positives = 88/260 (33%), Gaps = 20/260 (7%)

Query: 360 GGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASR 419
           GGA +   P AP      +  ++      P P P+           P A+  SS  P+ R
Sbjct: 305 GGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQR 364

Query: 420 GAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSR-RDGLLTMLPGPPP 478
             PR PP    F L        PR         +P    +P P       +L++L  P P
Sbjct: 365 -RPRRPPTV--FRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTP 421

Query: 479 VYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEG-----PEVHPNPLLWMPPPTRIPSA 533
             +    S  L   D H     T   G PP+         P      L  +P     P+A
Sbjct: 422 GPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAA 481

Query: 534 GERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGA- 592
            +     +  L+   +      G+ AGP   P+ P  G    PF      E G AL GA 
Sbjct: 482 SKAPVVPSPVLQSPSE----GLGMGAGP-ACPLPPLAGGEAFPFPSP---EQGLALSGAG 533

Query: 593 -PSQ-APLPHSRSFTAPPVS 610
            P     LP   S   PP S
Sbjct: 534 FPGMLGALPLPLSLGQPPPS 553


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 165/655 (25%), Positives = 222/655 (33%), Gaps = 148/655 (22%)

Query: 56  PPECPLEPGERPQLVR----RRPPTARAYPP---PHPNQAHHSLCPAEELALEALEREVS 108
           PP  P  P + P  +     + PP+ +  PP   PH   +     P   LAL +L+   S
Sbjct: 360 PPATP--PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417

Query: 109 VQQQIAAAARR-LALAPDLSTEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLP-- 165
           +      A    L ++P        R+ Q    +  R          ++A L LP  P  
Sbjct: 418 LGSPTLQATHSFLTMSP--------RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469

Query: 166 ----LPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVV-------LHSESS----SLSESG 210
                P   PLS  S +T   +     LA  S +  +       L ++SS    SL    
Sbjct: 470 QTSLSPAVSPLS--SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527

Query: 211 ASHDNEEPHGCFSLAERP----SPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRR 266
           AS          SLA  P    S P     L      +P    P + PPS L        
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP---CPLQAPPSPLTTPPPETP 584

Query: 267 NSVASP---------TSPTRSLPRSASSFEGR------------------SVPATPVLTR 299
           +S+A+P         + P + LP    S                      S PA+P L+ 
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644

Query: 300 GAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAG 359
            A P    P  L               P   P S  AS  V+ +    S     +     
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 704

Query: 360 GGAGSPPA--PLAPSASGPPVCK---SSEVLYERPQP--TPAFSSRTAGPP-------DP 405
               SPPA  P++PSA+ PP      ++  L   P P  +P  S     PP        P
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764

Query: 406 PRAARPSSAA-----PASRGAPRLPPVCGDFLLDYSLDRGLPRSGGG-TGWGELPPAAEV 459
           P    PS  A     P ++  P+ PP      L     + LP       G     P+A +
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPL-----QALPSPPASFPGQAPFSPSASL 819

Query: 460 PGPLSRRDGLLTMLPGPPPVYAADSNSPLLRT-----KDPHTRATRTKPCGLPPEAAEGP 514
           P        L T  P  PPV AA    PLL+        P  +A R  P   P  +  GP
Sbjct: 820 P-----MSPLATPPPQAPPVLAA----PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 870

Query: 515 E----VHPNPLLWMPPPTRIPSA----GERSGHKNLAL---EGLRDWYI-RNSGLAAGPQ 562
                + P P    PPP+R PS+     + +GH + A    E LR +      G AA P 
Sbjct: 871 RLTLALAPGP---PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 927

Query: 563 RRPVLPSVGP------PHPPFLHARCYEVGQALYGAPSQAPLPHSRSFTAPPVSG 611
               L +  P      P PP           A  GAP  APLP       PP +G
Sbjct: 928 PDAELAACHPAAWSRGPAPPL----------AFRGAPG-APLPW------PPATG 965



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/292 (24%), Positives = 104/292 (35%), Gaps = 42/292 (14%)

Query: 227 RPSPPKAWDQLRAVSGGSPERRTPWKPP----PSDLYGDLKSRRNSVASPTSPTRSLPRS 282
           RP PP    + ++VS  S    T   P     PS   G  +    S++S  +P  S  RS
Sbjct: 197 RPRPPTEGPR-KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255

Query: 283 ASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVAR 342
             S   R  P  P     A P   KP+GL + +       Q+  PR D A     L  + 
Sbjct: 256 GPS--ARGTPRAP-----AHPSQPKPKGLQALR-----PPQVTPPRKDAAPALGPLSSSP 303

Query: 343 TRRSNSSEALLVDRAAGGGAGSP-PAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAG 401
               + S            A +P PA L PS   PP+     +    P   P+  +  + 
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPS---PPLATPLPLAPPSPSAPPSLQTLPSP 360

Query: 402 PPDPPRAARPSSAAPASRGAPRL---PPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAE 458
           P  PP  A PS   P  +  P L   PP+     + +SL                P    
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPI----QVPHSLTS--------------PSLQA 402

Query: 459 VPGPLSRRDGLLTMLPGPPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEA 510
            P PL+      T   G P + A  S   +   +   +  + ++P   PP++
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 78/334 (23%), Positives = 108/334 (32%), Gaps = 48/334 (14%)

Query: 227 RPSPPKAWDQLRAVSGGSPERRTPWK-----------PPPSDLYGDLKSRRNSVASPTSP 275
           RP PP     LR +       R P             P  +   G  +S   S  +P S 
Sbjct: 34  RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASR 93

Query: 276 TRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDR 335
             +  R   +   ++    PV + G      +P  L  +    S +  +   +A  A  R
Sbjct: 94  PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 153

Query: 336 ASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAF 395
           ++L  A  RR  S              G  P   +P+ +       +EV   RP P+   
Sbjct: 154 SALS-AGARRDTS--------------GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198

Query: 396 SSRTAGPPDPPRAARPSSAAPASRGAPRLPPVCGDF-------LLDYSLDRGLPRSGGGT 448
              T GP     +A   S    S  A R P   G         L   +     P   G +
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258

Query: 449 GWGELPPAAEVPGPLSRRDGLLTMLP---GPPPVYAADSNSPL----LRTKDPHTRATRT 501
             G   P A       +  GL  + P    PP   AA +  PL    L T  P     R 
Sbjct: 259 ARG--TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316

Query: 502 KPCGLPPEAAEGP---EVHPNPLLWMPPPTRIPS 532
            P   PP+ A  P    + P+P L  P P   PS
Sbjct: 317 VP---PPDNAATPLPATLPPSPPLATPLPLAPPS 347



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 52/213 (24%), Positives = 65/213 (30%), Gaps = 32/213 (15%)

Query: 406 PRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRG------LPRSGGGTGWGELPPAAEV 459
           P A  P    P   G+PR PP      L      G      L    GG G   +P +A  
Sbjct: 17  PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76

Query: 460 PGPLSRRDGLLTMLPGP-PPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHP 518
            GP +R  G  +  P   PP       +P  +   P                  GP   P
Sbjct: 77  AGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSP------------------GPVSSP 117

Query: 519 NPLLWMPPPTRIPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFL 578
                   P  +   G R   +     G      + S L+AG +R    P+ G P P   
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM- 176

Query: 579 HARCYEVGQALYGAPSQAPLPHSRSFTAPPVSG 611
            AR         G P  AP    R    PP  G
Sbjct: 177 -ARRSRAAGTEVGLPRPAPSARPR----PPTEG 204


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 133/579 (22%), Positives = 196/579 (33%), Gaps = 126/579 (21%)

Query: 70  VRRRPPTARAYPPPHPNQAH--HSLCPAEELAL--EALEREVSVQQQIAAAAR-RLALAP 124
           VR  P  +  YP   P  +H      PA +  +  E++ R  S +       + ++   P
Sbjct: 334 VRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNP 393

Query: 125 DL------STEQRRRRRQVQADALRRLHELEEQLRDVRARLGLPVLPLPQPLPLSTGSVI 178
           DL      + E+RR+R Q +         L  +  + +        P  +  P +   V+
Sbjct: 394 DLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPA----PRDRASPAAAEEVV 449

Query: 179 TTQGVCL-------------GMRLAQLSQEDVVLHSESSSLSES----GASHDNEEPHGC 221
                CL                L++ S +   L++   S  E      +SH  E     
Sbjct: 450 PEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE----- 504

Query: 222 FSLAERPSP----PKAWDQLRAVSGG-SPERRTPWKPPPSDLY-------GDLKSRRNS- 268
             LA  PSP    P +W       G      R+P + PP+ LY       G L+      
Sbjct: 505 --LARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQ 562

Query: 269 ----------VASPTS-PTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWS 317
                     V SP   P +  PR+AS  +  S+   P L +GA P              
Sbjct: 563 PPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPP------------- 609

Query: 318 GSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPP 377
                      A P   R+S  +  +   +S +   V    GG      +P++PS +  P
Sbjct: 610 ---------SPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDI----SPVSPSRAWSP 656

Query: 378 VCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSL 437
             K +        P P+FS+R AG     R     ++ P + GA R P       LD  +
Sbjct: 657 RAKQA--------PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPS-----SLDGWV 703

Query: 438 DRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADS------------- 484
             G    G G+     PP    P P+S      ++ P  P   A                
Sbjct: 704 SPGPWEPGRGSSMSS-PPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNII 762

Query: 485 NSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHKNLAL 544
           N+   ++  P +          PP A   P   P P    PP  R P    R G  + A+
Sbjct: 763 NAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPP----PPRMRSPQPA-RPG--SAAV 815

Query: 545 EGLRDWYIRNSGLAAGPQ--RRPVLPSVGPPHPPFLHAR 581
            G     I  S L AGP     P  P   PP  PFL+ R
Sbjct: 816 PGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPR-PFLYRR 853


>gi|33286436 gametogenetin [Homo sapiens]
          Length = 652

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 114/428 (26%), Positives = 153/428 (35%), Gaps = 102/428 (23%)

Query: 227 RPSPPKAWDQLRAVSGGSPERRTP----WKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 282
           +P PP     ++     +P +  P    WKPPP      L S R       +P  + P S
Sbjct: 143 KPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPP-----LPSERQPADRRITPALATPAS 197

Query: 283 ASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQ--DSQMGFPRADPASDRASLFV 340
             + E ++ P     T G       P   H+ +   +Q  DS+ G       + ++   +
Sbjct: 198 PPT-ESQAGPRNQGQTAGRARGGAPP---HAGEGEMAQPADSESGLSLLCKITFKSRPSL 253

Query: 341 ARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFS---- 396
           A    S+S   L    + GGG G        +ASG      +EVL + P P  A      
Sbjct: 254 APPAASSS---LAAKASLGGGGGGGLF----AASG--AISYAEVLKQGPLPPGAARPLGE 304

Query: 397 -SRTA-----GPPDPPRAARPSSAAPASRGAPRLPPVCGDF-----LLDY-SLDRGLPR- 443
            SR A     G  D    + P SA PAS+     PP    F       D+ S   G  R 
Sbjct: 305 VSRGAQEAEGGDGDGEGCSGPPSA-PASQARALPPPPYTTFPGSKPKFDWVSAPDGPERH 363

Query: 444 -----SGGGTG------------WGELPPAAE----VPGPLSRRDGLLTMLPGPPPVYAA 482
                +GGG G            WG  PP  E     PGP  RR     + P P  ++ A
Sbjct: 364 FRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGP--RRPAPALLAP-PTFIFPA 420

Query: 483 DSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPSAGERSGHKNL 542
            +N   +R   P  +     P   PP   + P + P PL   PP T         GHK  
Sbjct: 421 PTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLT------PGLGHKES 474

Query: 543 ALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPHSR 602
           AL                       P+  P  PP L A      QA   APS AP P + 
Sbjct: 475 AL----------------------APTAAPALPPALAA-----DQA--PAPSPAPAP-TV 504

Query: 603 SFTAPPVS 610
           +  +PPVS
Sbjct: 505 AEPSPPVS 512



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 60/254 (23%), Positives = 82/254 (32%), Gaps = 65/254 (25%)

Query: 222 FSLAERPSPPKAWDQLRAVSGG--SPERRT-----PW---KPPPSDLYGDLKSRRNSVAS 271
           F     P  P+   +     GG  +P RR      PW    PPP  ++     RR + A 
Sbjct: 351 FDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPAL 410

Query: 272 PTSPTRSLPRSASSFEGRSVPA----TPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFP 327
              PT   P   +    R  P      P L     P   +P  L               P
Sbjct: 411 LAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTP----------LP 460

Query: 328 RADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYE 387
            A P +                           G G   + LAP+A+  P    +    +
Sbjct: 461 VAPPLTP--------------------------GLGHKESALAPTAA--PALPPALAADQ 492

Query: 388 RPQPTPAFSSRTAGPPDPPRAARPSSAAP------------ASRGAPRLPPVCGDFLLDY 435
            P P+PA  + T   P PP +A   +AAP            A+RGA R   + GD   + 
Sbjct: 493 APAPSPA-PAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRER 551

Query: 436 SLDRGLPRSGGGTG 449
           +       SGGG G
Sbjct: 552 ATATVPDSSGGGGG 565


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 71/251 (28%), Positives = 80/251 (31%), Gaps = 75/251 (29%)

Query: 355 DRAAG-GGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSS 413
           DR  G  G G PP P  P+   PP          RP   P       GPP P +   P  
Sbjct: 215 DRFPGPAGPGGPPPPF-PAGQTPP----------RPPLGPPGPPGPPGPPPPGQVLPPPL 263

Query: 414 AAPASRGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPA--------AEVPGPLSR 465
           A P +RG    PPV         L  G P   G    G LPP            PGP   
Sbjct: 264 AGPPNRGDRPPPPV---------LFPGQP--FGQPPLGPLPPGPPPPVPGYGPPPGPPPP 312

Query: 466 RDGLLTMLPGP-PPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWM 524
           + G     PGP PP        PL     PH           PP  A  P  H NP  + 
Sbjct: 313 QQG-PPPPPGPFPPRPPGPLGPPLTLAPPPHLPG--------PPPGAPPPAPHVNP-AFF 362

Query: 525 PPPTRIPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYE 584
           PPPT                         NSG+     R P      PP  P+     Y+
Sbjct: 363 PPPT-------------------------NSGMPTSDSRGP------PPTDPYGRPPPYD 391

Query: 585 VGQALYGAPSQ 595
            G   YG P +
Sbjct: 392 RGD--YGPPGR 400


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 85/349 (24%), Positives = 122/349 (34%), Gaps = 79/349 (22%)

Query: 200 HSESSSLSESGASHDNEEP------HGCFSLAERPSP-----PKAWDQLRAVSGGSPERR 248
           + +SSS S S +S ++E P      +G      R SP     P    + +  S     RR
Sbjct: 489 NQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRR 548

Query: 249 TPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKP 308
           +P  PP         +RR    SP  P R   R+ +    R  P+ P   R   P+   P
Sbjct: 549 SPSPPP---------TRRRRSPSPAPPPRRR-RTPTPPPRRRTPSPPPRRRSPSPRRYSP 598

Query: 309 EGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGSPPAP 368
                R++S         P   P    AS      RR++ S               PP  
Sbjct: 599 P--IQRRYS---------PSPPPKRRTASPPPPPKRRASPS---------------PPPK 632

Query: 369 LAPSASGPPVCKSSEVLYERPQP---------TPAFSSRTAGPPDPPRAARPSSAAPASR 419
              S S PP  +SS V   R            +P+ S+R A  P P +   PS    A +
Sbjct: 633 RRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692

Query: 420 GAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPV 479
            +   PPV               R G  +     P   + P P +R    ++  P P  +
Sbjct: 693 TSSSPPPV---------------RRGASSS----PQRRQSPSPSTRPIRRVSRTPEPKKI 733

Query: 480 YAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPT 528
             A S SP    +   +R+      G P  AA+ P   P+P+    P T
Sbjct: 734 KKAASPSPQSVRRVSSSRSV----SGSPEPAAKKPPAPPSPVQSQSPST 778



 Score = 36.6 bits (83), Expect = 0.070
 Identities = 54/203 (26%), Positives = 70/203 (34%), Gaps = 37/203 (18%)

Query: 225 AERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASP-----TSPTRSL 279
           A  P PPK     RA     P+RR    PPP      +  RR+   S      +SP+RS 
Sbjct: 615 ASPPPPPKR----RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST 670

Query: 280 PRSASSFEGRSVPATPVLTRGAGPQL-CKPEGLHSRQWSGSQDSQMGFPRADP------- 331
             + S    +    +P   R   PQ    P  +     S  Q  Q   P   P       
Sbjct: 671 REARSPQPNKRHSPSP---RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRT 727

Query: 332 -----ASDRASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEV-- 384
                    AS      RR +SS +  V  +    A  PPAP +P  S  P    S    
Sbjct: 728 PEPKKIKKAASPSPQSVRRVSSSRS--VSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785

Query: 385 LYERPQPTPAFSSRTAGPPDPPR 407
           + +   PTP+        P PPR
Sbjct: 786 VKKAKSPTPS--------PSPPR 800


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 85/333 (25%), Positives = 106/333 (31%), Gaps = 63/333 (18%)

Query: 206 LSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSR 265
           L+ S A   NE+     S  E PS      + R   GG+  +RTP  PPP    G     
Sbjct: 11  LALSSAQSLNED----VSQEESPSVISGKPEGRRPQGGNQPQRTP--PPPGKPEGRPPQG 64

Query: 266 RNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDS--Q 323
            N    P  P    P       G         ++G  P+  KPEG   +  + SQ    +
Sbjct: 65  GNQSQGPP-PRPGKPEGPPPQGGNQ-------SQGPPPRPGKPEGQPPQGGNQSQGPPPR 116

Query: 324 MGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSE 383
            G P   P               N S+            G PP P  P   GPP    ++
Sbjct: 117 PGKPEGPPPQG-----------GNQSQ------------GPPPRPGKPE--GPPPQGGNQ 151

Query: 384 VLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDR---- 439
              + P P P    +  GPP  P+    S   P   G P  PP  G         R    
Sbjct: 152 S--QGPPPRPG---KPEGPP--PQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKP 204

Query: 440 -GLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADSNSPLLRTKDPHTRA 498
            G P  GG    G  P   +  GP S+         GPPP        P      P    
Sbjct: 205 EGPPPQGGNQSQGPPPRPGKPEGPPSQGGN---KPQGPPPHPGKPQGPPPQEGNKPQRPP 261

Query: 499 TRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIP 531
              +P G PP          NP   +PPP   P
Sbjct: 262 PPGRPQGPPPPGG-------NPQQPLPPPAGKP 287



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 63/238 (26%), Positives = 74/238 (31%), Gaps = 50/238 (21%)

Query: 388 RPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDR-----GLP 442
           +PQ TP    +  G P  P+    S   P   G P  PP  G         R     G P
Sbjct: 46  QPQRTPPPPGKPEGRP--PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQP 103

Query: 443 RSGGGTGWGELPPAAEVPGPLSRRDGLLTMLP-------GPPPVYAADSNSPLLRTKDPH 495
             GG    G  P   +  GP  +        P       GPPP     S  P  R     
Sbjct: 104 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP---- 159

Query: 496 TRATRTKPCGLPPEA---AEGPEVHPNPLLWMPPPTRIPSAG--ERSGHKNLALEGLRDW 550
                 KP G PP+    ++GP  HP      PP     S G   R G      EG    
Sbjct: 160 -----GKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKP----EGPPP- 209

Query: 551 YIRNSGLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPHSRSFTAPP 608
             +    + GP  RP  P  GPP              +  G   Q P PH      PP
Sbjct: 210 --QGGNQSQGPPPRPGKPE-GPP--------------SQGGNKPQGPPPHPGKPQGPP 250



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 10/64 (15%)

Query: 363 GSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAP 422
           G PP P  P   GPP  + ++   +RP P      R  GPP P     P    P   G P
Sbjct: 238 GPPPHPGKPQ--GPPPQEGNKP--QRPPPP----GRPQGPPPP--GGNPQQPLPPPAGKP 287

Query: 423 RLPP 426
           + PP
Sbjct: 288 QGPP 291



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 16/47 (34%), Positives = 19/47 (40%), Gaps = 7/47 (14%)

Query: 365 PPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARP 411
           PP P  P    PP            QP P  + +  GPP PP+  RP
Sbjct: 260 PPPPGRPQGPPPPGGNPQ-------QPLPPPAGKPQGPPPPPQGGRP 299


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 91/374 (24%), Positives = 125/374 (33%), Gaps = 76/374 (20%)

Query: 216 EEPHGCFSLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRR-----NSVA 270
           E P     L  +   P  +D  +    G      P    P  L+    S R     +S  
Sbjct: 134 EPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSARTPGGGHSSG 193

Query: 271 SPTSPTRSLPRSASSFEGRSVPATPVL----TRGAGPQLCKPEGL----HSRQWSGSQDS 322
           +P   + S    A    GR     P+      R  G +   P G+       +  G QD 
Sbjct: 194 APAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDR 253

Query: 323 QMGFPRADPASDRASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPL------------- 369
             G PR    ++R S F+A ++  N++    V     GGAG    P              
Sbjct: 254 --GPPRL---AERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEA 308

Query: 370 APSASGPPVCKSSEVLYERPQPTPAF----SSRTAGPPDPPRAARPSSAAPASRG----- 420
           A    G  + + +E L   P+P P+      +   GPP PP AA P+      R      
Sbjct: 309 ARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPP-AATPAGVYTVFREQGREH 367

Query: 421 ---APRLPPVCGDF--------LLDYSLD-RGLPRSGGGTGWGELPPAAEVPGPLSRRDG 468
              AP   P    F        +   + D R   R  G  G  + PP +  P PL R +G
Sbjct: 368 RVVAPTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGS--PRPLDRPEG 425

Query: 469 L------LTMLPGPPPVYAADSNSPLLRTKDPHTRATRTKP---CGLPPEAAEGPEVHPN 519
           L      +  L  PPP  A            P  RATR  P     +P +    PE  P 
Sbjct: 426 LREKNSVIRSLKRPPPADA------------PTVRATRASPDPRAYVPAKELLKPEADPR 473

Query: 520 PLLWMPPPTRIPSA 533
           P    P     P+A
Sbjct: 474 PCERAPRGPAGPAA 487



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 52/226 (23%), Positives = 78/226 (34%), Gaps = 26/226 (11%)

Query: 201  SESSSLSESGASHDNEEPHG-CFSLAERPSPPKAWDQLRAVSGGSPERRTPWKP---PPS 256
            S+ +   + G +  +EEP         +PS     D+   +  G+P    P  P    PS
Sbjct: 2308 SKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPS 2367

Query: 257  DLYGDLKSRRNSV---------------ASPTSPTRSLPRSASSFEGRSVPAT-----PV 296
               G  KS    V                SP  P  +   +   F     PAT     P+
Sbjct: 2368 STPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPL 2427

Query: 297  LTRGAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDRASLFVARTRRSNSSEALLVDR 356
            +T  A     KP+   + + SG++  +     A+         V   +   + EALL+  
Sbjct: 2428 ITMPATRP--KPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRE 2485

Query: 357  AAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGP 402
              G G    P  L    S PP   SSE     P+ T    ++  GP
Sbjct: 2486 DPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGP 2531



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 11/98 (11%)

Query: 327  PRADPASDRASLFVAR--TRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEV 384
            P A    DRA+       T    S+   L   +  G   SPP P+   A  P    +   
Sbjct: 2336 PSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAP-- 2393

Query: 385  LYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGAP 422
                PQP+PA  + T+ P   P A  P   APA+  AP
Sbjct: 2394 ----PQPSPAPPAFTSCPAPEPFAELP---APATSLAP 2424


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 46/157 (29%), Positives = 59/157 (37%), Gaps = 25/157 (15%)

Query: 365 PPAPLAPSAS---GPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAAPASRGA 421
           P AP AP +S    PPV +SS+       P  A  +   G P PP    P    P     
Sbjct: 506 PRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDD 565

Query: 422 PRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYA 481
           P LPP   DF+                   E PP    P P S      + LP PPP   
Sbjct: 566 PELPPPPPDFM-------------------EPPPDFVPPPPPSYAGIAGSELPPPPPPPP 606

Query: 482 ADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHP 518
           A + +P+  +  P     +  P  +PP+  E P  HP
Sbjct: 607 APAPAPVPDSARPPPAVAKRPP--VPPKRQENPG-HP 640



 Score = 33.1 bits (74), Expect = 0.78
 Identities = 44/166 (26%), Positives = 63/166 (37%), Gaps = 32/166 (19%)

Query: 327 PRADPASDRASLF----VARTRRSNSSEA--LLVDRAAGGGAGSPPAPLAPSASGPPVCK 380
           PRA P + ++SL     V R+  ++ S A  L      GGG  +PP    P    PP   
Sbjct: 506 PRA-PHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLD 564

Query: 381 SSEVLYERP---QPTPAF------------SSRTAGPPDPPRAARPSSAAPASRGAP--- 422
             E+    P   +P P F             S    PP PP A  P+    ++R  P   
Sbjct: 565 DPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVA 624

Query: 423 RLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDG 468
           + PPV           +  P   GG G GE    +++   L ++ G
Sbjct: 625 KRPPV-------PPKRQENPGHPGGAGGGEQDFMSDLMKALQKKRG 663


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 76/292 (26%), Positives = 89/292 (30%), Gaps = 73/292 (25%)

Query: 330  DPASDRASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERP 389
            DPAS       AR R      AL      GG    PP P +P    PP        +   
Sbjct: 1348 DPASPLGLALAARER------ALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHH 1401

Query: 390  QPTPAFSSRTAGPPDPPRAARPSSAAPAS--RGAPRLPPVCGDFLLDYSLDRGLPRSGGG 447
            +P        A PPDP R      A   S  +  P  PP     LL              
Sbjct: 1402 EPVLRLWG--ASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLH------------- 1446

Query: 448  TGWGELPPAAEVPGPLSRRDGLLTMLPGP---PPVYAADSNSP--------LLRTKDPHT 496
                 LPP A   GPL  + G     P P    P  +A    P         L    P  
Sbjct: 1447 ----RLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRA 1502

Query: 497  RATRTKPCGLPPEAAEGPEV-HPNPLLWMPPPTRIPSAGERSGHKNLALEGLRDWYIRNS 555
              T     G  P + +GP V  P+P   +PP    P A E +G   L L           
Sbjct: 1503 PVT----SGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLP---------- 1548

Query: 556  GLAAGPQRRPVLPSVGPPHPPFLHARCYEVGQALYGAPSQAPLPHSRSFTAP 607
                     P  PSV             E G+ L+  P   PL  S SF  P
Sbjct: 1549 ---------PPAPSVD-----------VEDGEFLFVEPLPPPLEFSNSFEKP 1580



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 90/352 (25%), Positives = 110/352 (31%), Gaps = 94/352 (26%)

Query: 226  ERPS--PPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRSA 283
            ERPS  PP     LR  S G+ E   P+  PP+  +    S   S   P  PT S P   
Sbjct: 873  ERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPP 932

Query: 284  SSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGS---QDSQMGFPRADPASDRA---- 336
             S        TP +   +G     P G      SG      S   F    P   R     
Sbjct: 933  YS--------TPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSRE 984

Query: 337  -SLFVA---------------------RTRRSNSSEALLVDRAAGGGAGSPPAPLA---- 370
             SL+ +                     +    ++      +   GG    PP  LA    
Sbjct: 985  KSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQ 1044

Query: 371  PSASGPPVCKSSEVLYERPQPTPAFSS------------RTAGP-----PDPPRAARPSS 413
            PS  G             P PTP   S             + GP       PPRAA  + 
Sbjct: 1045 PSLRG--------WRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAM 1096

Query: 414  AAPASRGAPRLPPVCGDFLLDYSLDRGLPRSGGGTGWGELPPAAEVPGPLSRRDGLLTML 473
              PA  G  R  P     L+  +   G P+ GGG     LPPA     P S         
Sbjct: 1097 YVPARSGRGRKGP-----LVKQTKVEGEPQKGGG-----LPPAPSPTSPAS--------- 1137

Query: 474  PGPPPVYAADSNS-----PLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNP 520
            P PPP  AA S       P +  K P T ++     G   EA   P   P P
Sbjct: 1138 PQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAE--PPTQPEP 1187



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 68/271 (25%), Positives = 87/271 (32%), Gaps = 62/271 (22%)

Query: 365  PPAPLAPSASG---------PPVCKSSEV-----LYERPQPTPAFSSRTAGPPDPPRAAR 410
            PP+P +P AS          PP   S +V     L+  P P P   S +   P+ P    
Sbjct: 1528 PPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPG 1587

Query: 411  PSSAAPASRG-APRLPPV--------------CGDFLLDYSLDRGLPRSGGGTGWGEL-- 453
            P    P +   A  LPPV                  L  Y  +      G     G+   
Sbjct: 1588 PPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHP 1647

Query: 454  --PPAAEVPGPLSRRDGLLTMLPGPPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAA 511
              PPA   P P + + G     P PPP   +       R+   H   T +    L   +A
Sbjct: 1648 PGPPAPAAPAPAAPQPG-----PDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSA 1702

Query: 512  EGPEVHPNPLLWMPPPTRIPSAGERSGHKNLALEG--LRDWYIRN-SGLAAGPQRRPVLP 568
            EG                  SAG   G       G  L D Y+    G A G    P   
Sbjct: 1703 EGG----------------GSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTP--- 1743

Query: 569  SVGPPHPPFLHARCYEVGQALYGAPSQAPLP 599
              GPP+PP L       G+AL  +    P P
Sbjct: 1744 --GPPYPPQLMTPSKLRGRALGASGGLRPGP 1772



 Score = 36.2 bits (82), Expect = 0.092
 Identities = 101/386 (26%), Positives = 129/386 (33%), Gaps = 78/386 (20%)

Query: 160  GLPVLPLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDNEEPH 219
            GLP+L LP P P    SV    G            E + +      L  S +    E P 
Sbjct: 1541 GLPLLVLPPPAP----SVDVEDG------------EFLFVEPLPPPLEFSNSFEKPESPL 1584

Query: 220  GCFSLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGD--LKSRRNSVASPTSPTR 277
                    P PP       A     P    P  PPP+       L S  +S+ S  S   
Sbjct: 1585 -------TPGPPHPLPDTPA-----PATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVA 1632

Query: 278  SLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFPRADPASDR-- 335
            +L + AS+  G   P  P       P   +P             +  G    D  S    
Sbjct: 1633 TLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGP------DPPPGTDSGIEEVDSRSSSDH 1686

Query: 336  --ASLFVARTRRSNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTP 393
               ++  A T  S S+E      +AGGG G+     A  ASGP +   + V Y   Q   
Sbjct: 1687 PLETISSASTLSSLSAEG---GGSAGGGGGAG----AGVASGPELL-DTYVAYLDGQ--- 1735

Query: 394  AFS-SRTAGPPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGL-PRSGGGTGWG 451
            AF  S T GPP PP+   PS     + GA                  GL P   GG    
Sbjct: 1736 AFGGSSTPGPPYPPQLMTPSKLRGRALGA----------------SGGLRPGPSGGLRDP 1779

Query: 452  ELPPAAEVPGPLSRRDGLLTMLPGPPPVYAADSNSPLLRTKD----PHTRATRTKPCGLP 507
              P +  V    +  DGLL +     P  A  +  P+    +    P   A+      LP
Sbjct: 1780 VTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLP 1839

Query: 508  PEAAEGPEVHPNPLLWMPPPTRIPSA 533
             E  EGP   P PL   P P   P A
Sbjct: 1840 WE--EGPGPPPPPL---PGPLAQPQA 1860



 Score = 33.9 bits (76), Expect = 0.46
 Identities = 61/222 (27%), Positives = 72/222 (32%), Gaps = 38/222 (17%)

Query: 208  ESGASHDNEEPHGCFSLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRN 267
            E+G S D+  P     LA  P P      LR   GG P   TP  P PS  +G       
Sbjct: 1027 ETGGSPDDPPPR----LALGPQP-----SLRGWRGGGPSP-TPGAPSPSH-HGSAGGGGG 1075

Query: 268  SVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSGSQDSQMGFP 327
            S   P      LP  A+S     VPA     RG    L K   +      G      G P
Sbjct: 1076 SSQGPALRYFQLPPRAAS-AAMYVPARS--GRGRKGPLVKQTKVEGEPQKGG-----GLP 1127

Query: 328  RA----DPASDRASLFVARTRRSNSSEALLV----------DRAAGGGAGSPPAPLAPSA 373
             A     PAS +    VA     NS     +           R++ G +     P  P  
Sbjct: 1128 PAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEP 1187

Query: 374  SGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAARPSSAA 415
            +G      S      P P PA S     P   P  A PS  A
Sbjct: 1188 TGGGGGGGSS-----PSPAPAMSPVPPSPSPVPTPASPSGPA 1224



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 36/120 (30%), Positives = 42/120 (35%), Gaps = 27/120 (22%)

Query: 367 APLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDPPRAAR---------PSSAAPA 417
           AP A S+  P     S+   +   PT   SS T      PR AR         P  A   
Sbjct: 453 APGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQ 512

Query: 418 SRGAPRLPPVCGDFLLDYSLDRGLPRSG--GGTGWGELPPAAEVPGPLSRRDGLLTMLPG 475
            RG P                 G PR G  GGTG G   P   + G   RR  L + +PG
Sbjct: 513 PRGRPS--------------SSGTPREGPAGGTG-GSGGPGGSL-GSRGRRRKLYSAVPG 556


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 63/236 (26%), Positives = 77/236 (32%), Gaps = 50/236 (21%)

Query: 346 SNSSEALLVDRAAGGGAGSPPAPLAPSASGPPVCKSSEVLYERPQPTPAFSSRTAGPPDP 405
           S S+ A+ V  +    A  PPAP  P  SG  +          P P P  S+    PP P
Sbjct: 555 SLSAAAITVPPSVPSRAPVPPAPPLPGDSGTII---------PPPPAPGDSTTPPPPPPP 605

Query: 406 PRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPRSGGGT--GWGELPPAAEVPGPL 463
           P    P          P LP          ++    P SG  T      LP    +P P 
Sbjct: 606 PPPPPPLPGGVCISSPPSLPG-------GTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 658

Query: 464 SRRDGLLTMLPGPPPVYAADSNSPLLRTKDPHTRATRTKPCGLPPEAAEGPEVHPNP-LL 522
           S   G  T +P PPP+    +  P      P +      P  LP EA   P   P P   
Sbjct: 659 SLPGG--TAIPPPPPL-PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP 715

Query: 523 WMPPPTRIPSAGERSGHKNLALEGLRDWYIRNSGLAAGPQRRPVLPSVG-PPHPPF 577
            +PPP   P                            GP   P  P +G PP PPF
Sbjct: 716 GIPPPPPFP---------------------------GGPGIPPPPPGMGMPPPPPF 744


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,523,986
Number of Sequences: 37866
Number of extensions: 2218863
Number of successful extensions: 16035
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 1122
Number of HSP's that attempted gapping in prelim test: 11620
Number of HSP's gapped (non-prelim): 4448
length of query: 618
length of database: 18,247,518
effective HSP length: 108
effective length of query: 510
effective length of database: 14,157,990
effective search space: 7220574900
effective search space used: 7220574900
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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