Guide to the Human Genome
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Search of human proteins with 12056465

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12056465 fibrillarin [Homo sapiens]
         (321 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12056465 fibrillarin [Homo sapiens]                                660   0.0  
gi|109452587 family with sequence similarity 98, member B isofor...    94   2e-19
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]           87   2e-17
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]          87   2e-17
gi|55956899 keratin 9 [Homo sapiens]                                   80   3e-15
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b...    80   3e-15
gi|109148552 keratin 3 [Homo sapiens]                                  78   1e-14
gi|119395750 keratin 1 [Homo sapiens]                                  77   2e-14
gi|55956788 nucleolin [Homo sapiens]                                   76   3e-14
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap...    76   3e-14
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    76   5e-14
gi|109255251 loricrin [Homo sapiens]                                   73   4e-13
gi|195972866 keratin 10 [Homo sapiens]                                 72   7e-13
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...    72   7e-13
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform...    72   7e-13
gi|47132620 keratin 2 [Homo sapiens]                                   72   7e-13
gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]        71   1e-12
gi|9506713 nucleolar protein family A, member 1 [Homo sapiens]         71   1e-12
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...    69   6e-12
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    69   6e-12
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    69   6e-12
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...    69   6e-12
gi|56699482 hypothetical protein LOC25940 [Homo sapiens]               69   6e-12
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    67   2e-11
gi|194018511 keratin 77 [Homo sapiens]                                 67   3e-11
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ...    67   3e-11
gi|153791670 keratin 76 [Homo sapiens]                                 66   4e-11
gi|4502565 calpain, small subunit 1 [Homo sapiens]                     66   4e-11
gi|51599151 calpain, small subunit 1 [Homo sapiens]                    66   4e-11
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...    66   4e-11

>gi|12056465 fibrillarin [Homo sapiens]
          Length = 321

 Score =  660 bits (1704), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG 60
           MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG
Sbjct: 1   MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG 60

Query: 61  GGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGE 120
           GGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGE
Sbjct: 61  GGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGE 120

Query: 121 KRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDI 180
           KRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDI
Sbjct: 121 KRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDI 180

Query: 181 VGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQP 240
           VGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQP
Sbjct: 181 VGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQP 240

Query: 241 DQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLE 300
           DQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLE
Sbjct: 241 DQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLE 300

Query: 301 PYERDHAVVVGVYRPPPKVKN 321
           PYERDHAVVVGVYRPPPKVKN
Sbjct: 301 PYERDHAVVVGVYRPPPKVKN 321


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 49/82 (59%), Positives = 53/82 (64%), Gaps = 2/82 (2%)

Query: 3   PGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGG 62
           P +  R  G GGRGG+G  GG GGRGG GGG GRGG   G G  GGGGGGGGG GG GGG
Sbjct: 323 PPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGG 382

Query: 63  GFHSGGNRGRGRGGKRGNQSGK 84
           G   GG +GRG  G RG   G+
Sbjct: 383 G--RGGFQGRGDYGGRGGYGGR 402



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 46/77 (59%), Positives = 48/77 (62%), Gaps = 10/77 (12%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGG 68
           GGG GGRGG G  GGRGG GG GGG G GG       GGGGG GGGGGGGR  GGF   G
Sbjct: 341 GGGGGGRGGGGGGGGRGGWGGGGGGWGGGG-------GGGGGWGGGGGGGR--GGFQGRG 391

Query: 69  N-RGRGRGGKRGNQSGK 84
           +  GRG  G RG   G+
Sbjct: 392 DYGGRGGYGGRGGYGGR 408



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 45/79 (56%), Positives = 49/79 (62%), Gaps = 8/79 (10%)

Query: 9   GGGFGGRGGFGD-----RGGRGGRGGFGGGRGRG-GGFRGRG--RGGGGGGGGGGGGGRG 60
           GGG GGRGG+G       GG GG GG+GGG G G GGF+GRG   G GG GG GG GGRG
Sbjct: 350 GGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRG 409

Query: 61  GGGFHSGGNRGRGRGGKRG 79
            G  + GG  G G GG  G
Sbjct: 410 YGDPYGGGGGGGGGGGGGG 428



 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 36/52 (69%), Positives = 37/52 (71%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG 60
           GGG GGRGGF  RG  GGRGG+GG  G GG   G   GGGGGGGGGGGGG G
Sbjct: 378 GGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 40/73 (54%), Positives = 45/73 (61%), Gaps = 12/73 (16%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRG-----GGFRGRGRGGG-------GGG 51
           G+   GGG+GG GG G   G GG GG GG +GRG     GG+ GRG  GG       GGG
Sbjct: 358 GWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGG 417

Query: 52  GGGGGGGRGGGGF 64
           GGGGGGG GGGG+
Sbjct: 418 GGGGGGGGGGGGY 430


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 51/89 (57%), Positives = 56/89 (62%), Gaps = 14/89 (15%)

Query: 8   RGGGFGG--------RGGFG-DRGGRGG-RGGFGGGRGRG--GGFRGRGRGGGGGGGGGG 55
           RGGG+GG        RGG+G DRGG GG RGG+GG R RG  GG RG G G GG   GG 
Sbjct: 487 RGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGY 546

Query: 56  GGGRGGGGFHSGGNRGRGRGGKRGNQSGK 84
           GG R GGG+  GG+RG G GG RG   GK
Sbjct: 547 GGDRSGGGY--GGDRGGGYGGDRGGYGGK 573



 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 46/94 (48%), Positives = 51/94 (54%), Gaps = 18/94 (19%)

Query: 8   RGGGFGGRGGFGDRGGRGGR----------GGFGGGRGRGGGFRGRGRGGGGGG---GGG 54
           RG G+GG  G+  RGGRGG           GG+GG R  GGG+ G   GGG GG   GGG
Sbjct: 392 RGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGG 451

Query: 55  GGGGRGGG-----GFHSGGNRGRGRGGKRGNQSG 83
            GG RGGG     G   GG+RG G GG RG   G
Sbjct: 452 YGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGG 485



 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 46/87 (52%), Positives = 49/87 (56%), Gaps = 13/87 (14%)

Query: 7   PRGGGFGGRGGFGDRGGRGGRGGFGGGRG-----RGGGFRGRGRGGGGG-----GGGGGG 56
           P GG F GRG  G+RG RG RGG GG RG     R GG  G  R  GGG      GGG G
Sbjct: 386 PSGGDFRGRGYGGERGYRG-RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 444

Query: 57  GGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           G R GGG+  GG+RG G GG RG   G
Sbjct: 445 GDRSGGGY--GGDRGGGYGGDRGGGYG 469



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 48/85 (56%), Positives = 54/85 (63%), Gaps = 13/85 (15%)

Query: 8   RGGGFGG-RGGF--GDRGGRGGR--GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGG- 61
           RGGG+GG RGG   GDRGG GG   GG+GG RG  GG RG G GG  GG GG  GG GG 
Sbjct: 464 RGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG-GYGGDRGGYGGDRGGYGGD 522

Query: 62  ---GGFHSGGNRGRGRGGKRGNQSG 83
              GG+  GG+RG G  G  G++SG
Sbjct: 523 RSRGGY--GGDRG-GGSGYGGDRSG 544



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 44/92 (47%), Positives = 51/92 (55%), Gaps = 12/92 (13%)

Query: 4   GFSPRGGGFGG-RGGFG-DRGGRGG---RGGFGGGRGRGGGFRGRGRGG------GGGGG 52
           G+    GG+GG RGG+G DRGG GG   RGG+GG RG G G+ G   GG      GGG G
Sbjct: 497 GYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 556

Query: 53  GGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGK 84
           G  GGG GG     GG  G GR   R +Q  +
Sbjct: 557 GDRGGGYGGDRGGYGGKMG-GRNDYRNDQRNR 587



 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 50/85 (58%), Positives = 54/85 (63%), Gaps = 12/85 (14%)

Query: 8   RGGGFGG-RGGF--GDRGGR--GGRGGFGGGRGRG-GGFRGRGRGG--GGGGGGGGGGGR 59
           RGGG+GG RGG   GDRGG   G RGG+GG RG G GG RG G GG  GG GG  GG G 
Sbjct: 456 RGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG-GYGGDRGGYGGDRGGYGG 514

Query: 60  GGGGFHSGGNRGR-GRGGKRGNQSG 83
             GG+  GG+R R G GG RG  SG
Sbjct: 515 DRGGY--GGDRSRGGYGGDRGGGSG 537



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 42/80 (52%), Positives = 46/80 (57%), Gaps = 8/80 (10%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRG-GGFRGRG----RGGGGGGGGGGGGGRGGGG 63
           GGG+ G    G  GG    GG+GG RG G GG RG G    RGGG GG  GG GG  GGG
Sbjct: 431 GGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGG 490

Query: 64  FHSGGNRGRGRGGKRGNQSG 83
           +  GG+RG G GG RG   G
Sbjct: 491 Y--GGDRG-GYGGDRGGYGG 507



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 44/78 (56%), Positives = 47/78 (60%), Gaps = 6/78 (7%)

Query: 9   GGGFGG-RGGFGDRGGRGGRGGFGGGRGRG-GGFRGRGRGGGGGG-GGGGGGGRGGGGFH 65
           GGG+GG R G G  G RGG  G+GG RG G GG RG G GG  GG GG  GGG GG    
Sbjct: 440 GGGYGGDRSGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG 497

Query: 66  SGGNRGRGRGGKRGNQSG 83
            GG+RG G GG RG   G
Sbjct: 498 YGGDRG-GYGGDRGGYGG 514



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 44/83 (53%), Positives = 48/83 (57%), Gaps = 11/83 (13%)

Query: 9   GGGFGGR----GGF-GDR--GGRGG-RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG 60
           GGG+GG     GG+ GDR  GG GG R G G G  RGGG+ G   GG GG  GGG GG  
Sbjct: 421 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDR 480

Query: 61  GGGFHSGGNRGRGRGGKRGNQSG 83
           GG    GG+RG G GG RG   G
Sbjct: 481 GG---YGGDRGGGYGGDRGGYGG 500



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 41/76 (53%), Positives = 44/76 (57%), Gaps = 4/76 (5%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRG-GGFRGRGRGGGGGGGGGGGGGRGGGGFHSG 67
           GGG+GG  G G  G RGG  G+GG RG G GG RG   G  GGG GG  GG GG     G
Sbjct: 449 GGGYGGDRGGGYGGDRGG--GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG 506

Query: 68  GNRGRGRGGKRGNQSG 83
           G+RG G GG RG   G
Sbjct: 507 GDRG-GYGGDRGGYGG 521



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 46/126 (36%), Positives = 51/126 (40%), Gaps = 47/126 (37%)

Query: 2   KPGFSPRGGGFGGRGGFGDRGGRGGRGGFGG----------------------------- 32
           +P F   GG  GGR G G   GRGG  G GG                             
Sbjct: 318 RPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCN 377

Query: 33  ------GRGRGGGFRG---------RGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGK 77
                  R  GG FRG         RGRGG GG  GG GG R GGG+  GG+R  G GG 
Sbjct: 378 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGY--GGDRSSG-GGY 434

Query: 78  RGNQSG 83
            G++SG
Sbjct: 435 SGDRSG 440



 Score = 35.8 bits (81), Expect = 0.052
 Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)

Query: 24  RGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGG-RGGGGFHSGGNR 70
           RG  G  GGGRGRGG +   GRG   G  GG  GG +  GG    G R
Sbjct: 172 RGYGGSQGGGRGRGG-YDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPR 218



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 1/45 (2%)

Query: 29  GFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRG 73
           G+GG +G G G  G  + G G   G  GG RGG   + GG+R  G
Sbjct: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK-NFGGHRDYG 216



 Score = 32.7 bits (73), Expect = 0.44
 Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 6/46 (13%)

Query: 39  GFRGRGRGGGGGGGGGGGG----GRGGGGFHSGGNRG--RGRGGKR 78
           G   RG GG  GGG G GG    GRG     SGG+RG  +  GG R
Sbjct: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHR 213



 Score = 32.0 bits (71), Expect = 0.76
 Identities = 20/44 (45%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 11  GFGGRGGFGDRGGRGGRGGFG-GGRGRGGGFRGRGRGGGGGGGG 53
           G   RG  G +GG  GRGG+   GRG   G  G  RGG    GG
Sbjct: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 3/41 (7%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRG 44
           G+    GG  GRGG+ D+ GRG   G  G  G  GGF+  G
Sbjct: 173 GYGGSQGGGRGRGGY-DKDGRGPMTGSSG--GDRGGFKNFG 210



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 15/32 (46%), Positives = 15/32 (46%)

Query: 48  GGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRG 79
           G GG  GGG GRGG      G      GG RG
Sbjct: 173 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG 204



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 18/37 (48%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 56  GGGRGGGGFHSGGNRGRGRGGKRGN--QSGKNVMVEP 90
           GGG GGG    GG RGRG    RG   +SG  V   P
Sbjct: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNP 360


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 51/89 (57%), Positives = 56/89 (62%), Gaps = 14/89 (15%)

Query: 8   RGGGFGG--------RGGFG-DRGGRGG-RGGFGGGRGRG--GGFRGRGRGGGGGGGGGG 55
           RGGG+GG        RGG+G DRGG GG RGG+GG R RG  GG RG G G GG   GG 
Sbjct: 490 RGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGY 549

Query: 56  GGGRGGGGFHSGGNRGRGRGGKRGNQSGK 84
           GG R GGG+  GG+RG G GG RG   GK
Sbjct: 550 GGDRSGGGY--GGDRGGGYGGDRGGYGGK 576



 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 46/94 (48%), Positives = 51/94 (54%), Gaps = 18/94 (19%)

Query: 8   RGGGFGGRGGFGDRGGRGGR----------GGFGGGRGRGGGFRGRGRGGGGGG---GGG 54
           RG G+GG  G+  RGGRGG           GG+GG R  GGG+ G   GGG GG   GGG
Sbjct: 395 RGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGG 454

Query: 55  GGGGRGGG-----GFHSGGNRGRGRGGKRGNQSG 83
            GG RGGG     G   GG+RG G GG RG   G
Sbjct: 455 YGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGG 488



 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 46/87 (52%), Positives = 49/87 (56%), Gaps = 13/87 (14%)

Query: 7   PRGGGFGGRGGFGDRGGRGGRGGFGGGRG-----RGGGFRGRGRGGGGG-----GGGGGG 56
           P GG F GRG  G+RG RG RGG GG RG     R GG  G  R  GGG      GGG G
Sbjct: 389 PSGGDFRGRGYGGERGYRG-RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 447

Query: 57  GGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           G R GGG+  GG+RG G GG RG   G
Sbjct: 448 GDRSGGGY--GGDRGGGYGGDRGGGYG 472



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 48/85 (56%), Positives = 54/85 (63%), Gaps = 13/85 (15%)

Query: 8   RGGGFGG-RGGF--GDRGGRGGR--GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGG- 61
           RGGG+GG RGG   GDRGG GG   GG+GG RG  GG RG G GG  GG GG  GG GG 
Sbjct: 467 RGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG-GYGGDRGGYGGDRGGYGGD 525

Query: 62  ---GGFHSGGNRGRGRGGKRGNQSG 83
              GG+  GG+RG G  G  G++SG
Sbjct: 526 RSRGGY--GGDRG-GGSGYGGDRSG 547



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 44/92 (47%), Positives = 51/92 (55%), Gaps = 12/92 (13%)

Query: 4   GFSPRGGGFGG-RGGFG-DRGGRGG---RGGFGGGRGRGGGFRGRGRGG------GGGGG 52
           G+    GG+GG RGG+G DRGG GG   RGG+GG RG G G+ G   GG      GGG G
Sbjct: 500 GYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYG 559

Query: 53  GGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGK 84
           G  GGG GG     GG  G GR   R +Q  +
Sbjct: 560 GDRGGGYGGDRGGYGGKMG-GRNDYRNDQRNR 590



 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 50/85 (58%), Positives = 54/85 (63%), Gaps = 12/85 (14%)

Query: 8   RGGGFGG-RGGF--GDRGGR--GGRGGFGGGRGRG-GGFRGRGRGG--GGGGGGGGGGGR 59
           RGGG+GG RGG   GDRGG   G RGG+GG RG G GG RG G GG  GG GG  GG G 
Sbjct: 459 RGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG-GYGGDRGGYGGDRGGYGG 517

Query: 60  GGGGFHSGGNRGR-GRGGKRGNQSG 83
             GG+  GG+R R G GG RG  SG
Sbjct: 518 DRGGY--GGDRSRGGYGGDRGGGSG 540



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 42/80 (52%), Positives = 46/80 (57%), Gaps = 8/80 (10%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRG-GGFRGRG----RGGGGGGGGGGGGGRGGGG 63
           GGG+ G    G  GG    GG+GG RG G GG RG G    RGGG GG  GG GG  GGG
Sbjct: 434 GGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGG 493

Query: 64  FHSGGNRGRGRGGKRGNQSG 83
           +  GG+RG G GG RG   G
Sbjct: 494 Y--GGDRG-GYGGDRGGYGG 510



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 44/78 (56%), Positives = 47/78 (60%), Gaps = 6/78 (7%)

Query: 9   GGGFGG-RGGFGDRGGRGGRGGFGGGRGRG-GGFRGRGRGGGGGG-GGGGGGGRGGGGFH 65
           GGG+GG R G G  G RGG  G+GG RG G GG RG G GG  GG GG  GGG GG    
Sbjct: 443 GGGYGGDRSGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGG 500

Query: 66  SGGNRGRGRGGKRGNQSG 83
            GG+RG G GG RG   G
Sbjct: 501 YGGDRG-GYGGDRGGYGG 517



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 44/83 (53%), Positives = 48/83 (57%), Gaps = 11/83 (13%)

Query: 9   GGGFGGR----GGF-GDR--GGRGG-RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG 60
           GGG+GG     GG+ GDR  GG GG R G G G  RGGG+ G   GG GG  GGG GG  
Sbjct: 424 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDR 483

Query: 61  GGGFHSGGNRGRGRGGKRGNQSG 83
           GG    GG+RG G GG RG   G
Sbjct: 484 GG---YGGDRGGGYGGDRGGYGG 503



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 41/76 (53%), Positives = 44/76 (57%), Gaps = 4/76 (5%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRG-GGFRGRGRGGGGGGGGGGGGGRGGGGFHSG 67
           GGG+GG  G G  G RGG  G+GG RG G GG RG   G  GGG GG  GG GG     G
Sbjct: 452 GGGYGGDRGGGYGGDRGG--GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG 509

Query: 68  GNRGRGRGGKRGNQSG 83
           G+RG G GG RG   G
Sbjct: 510 GDRG-GYGGDRGGYGG 524



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 46/126 (36%), Positives = 51/126 (40%), Gaps = 47/126 (37%)

Query: 2   KPGFSPRGGGFGGRGGFGDRGGRGGRGGFGG----------------------------- 32
           +P F   GG  GGR G G   GRGG  G GG                             
Sbjct: 321 RPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCN 380

Query: 33  ------GRGRGGGFRG---------RGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGK 77
                  R  GG FRG         RGRGG GG  GG GG R GGG+  GG+R  G GG 
Sbjct: 381 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGY--GGDRSSG-GGY 437

Query: 78  RGNQSG 83
            G++SG
Sbjct: 438 SGDRSG 443



 Score = 35.8 bits (81), Expect = 0.052
 Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 2/48 (4%)

Query: 24  RGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGG-RGGGGFHSGGNR 70
           RG  G  GGGRGRGG +   GRG   G  GG  GG +  GG    G R
Sbjct: 175 RGYGGSQGGGRGRGG-YDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPR 221



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 1/45 (2%)

Query: 29  GFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRG 73
           G+GG +G G G  G  + G G   G  GG RGG   + GG+R  G
Sbjct: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK-NFGGHRDYG 219



 Score = 32.7 bits (73), Expect = 0.44
 Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 6/46 (13%)

Query: 39  GFRGRGRGGGGGGGGGGGG----GRGGGGFHSGGNRG--RGRGGKR 78
           G   RG GG  GGG G GG    GRG     SGG+RG  +  GG R
Sbjct: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHR 216



 Score = 32.0 bits (71), Expect = 0.76
 Identities = 20/44 (45%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 11  GFGGRGGFGDRGGRGGRGGFG-GGRGRGGGFRGRGRGGGGGGGG 53
           G   RG  G +GG  GRGG+   GRG   G  G  RGG    GG
Sbjct: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 3/41 (7%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRG 44
           G+    GG  GRGG+ D+ GRG   G  G  G  GGF+  G
Sbjct: 176 GYGGSQGGGRGRGGY-DKDGRGPMTGSSG--GDRGGFKNFG 213



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 15/32 (46%), Positives = 15/32 (46%)

Query: 48  GGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRG 79
           G GG  GGG GRGG      G      GG RG
Sbjct: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRG 207



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 18/37 (48%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 56  GGGRGGGGFHSGGNRGRGRGGKRGN--QSGKNVMVEP 90
           GGG GGG    GG RGRG    RG   +SG  V   P
Sbjct: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNP 363


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 43/85 (50%), Positives = 45/85 (52%), Gaps = 11/85 (12%)

Query: 10  GGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGR-----------GRGGGGGGGGGGGGG 58
           GG GG GG   RG RGG GG  GG G GGG+ G            G G G GGG GGG G
Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYG 535

Query: 59  RGGGGFHSGGNRGRGRGGKRGNQSG 83
            G GG HSGG+ G   GG  GN  G
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGGNYGG 560



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 39/75 (52%), Positives = 41/75 (54%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGG 68
           GGG G RGG G   G G   G G G G GGG  G   GG GGG  GG GG  GGG  SGG
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGG 566

Query: 69  NRGRGRGGKRGNQSG 83
             G G GG  G++ G
Sbjct: 567 GSGGGYGGGSGSRGG 581



 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 39/73 (53%), Positives = 40/73 (54%), Gaps = 2/73 (2%)

Query: 11  GFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNR 70
           G GGRGG G   GRG RGG GG  G GG   G G GGG G  GG GG  GGG    GG+ 
Sbjct: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGS--GGGYGGGSGSRGGSGGSYGGGSGSGGGSG 531

Query: 71  GRGRGGKRGNQSG 83
           G   GG  G  SG
Sbjct: 532 GGYGGGSGGGHSG 544



 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 42/91 (46%), Positives = 46/91 (50%), Gaps = 15/91 (16%)

Query: 9   GGGFGGRGGFGDRGGRGGR------GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGG- 61
           GGG+GG  G G  GG GG       G +GGG G GGG  G G GGG G  GG GG  GG 
Sbjct: 531 GGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGG-SGGGYGGGSGSRGGSGGSHGGG 589

Query: 62  -------GGFHSGGNRGRGRGGKRGNQSGKN 85
                  GG + GG    G GG  G  SGK+
Sbjct: 590 SGFGGESGGSYGGGEEASGSGGGYGGGSGKS 620



 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 42/77 (54%), Positives = 44/77 (57%), Gaps = 3/77 (3%)

Query: 9   GGGFGGRG-GFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSG 67
           GG +GG G G G  GG G RGG GG  G G G  G G GGG GGG GGG   G GG HSG
Sbjct: 494 GGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG-SGGGSGGGYGGGSGGGHSGGSGGGHSG 552

Query: 68  GNRGR-GRGGKRGNQSG 83
           G+ G  G G   G  SG
Sbjct: 553 GSGGNYGGGSGSGGGSG 569



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 42/88 (47%), Positives = 43/88 (48%), Gaps = 10/88 (11%)

Query: 6   SPRGGGFGGR--------GGFGDRGGRGGRGGFGG--GRGRGGGFRGRGRGGGGGGGGGG 55
           S  GGG GGR        GG     GRGG G FG   G G GGGF     GGG GGG  G
Sbjct: 37  SSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRG 96

Query: 56  GGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
            GG  GGG+ S G  G G GG  G   G
Sbjct: 97  FGGASGGGYSSSGGFGGGFGGGSGGGFG 124



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 39/82 (47%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGG--GGGGGGRGG 61
           G S  GGG GG  G G  GG  G  G G   G GG + G    GGG GG  GGG G RGG
Sbjct: 522 GGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGG 581

Query: 62  GGFHSGGNRGRGRGGKRGNQSG 83
            G   GG  G G GG+ G   G
Sbjct: 582 SGGSHGG--GSGFGGESGGSYG 601



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 36/77 (46%), Positives = 37/77 (48%), Gaps = 2/77 (2%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRG--GGFRGRGRGGGGGGGGGGGGGRGGGGFHS 66
           GGG G  GG G   G G  GG  GG G G  GG  G   GG G GGG GGG  GG G   
Sbjct: 521 GGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRG 580

Query: 67  GGNRGRGRGGKRGNQSG 83
           G     G G   G +SG
Sbjct: 581 GSGGSHGGGSGFGGESG 597



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 42/80 (52%), Positives = 43/80 (53%), Gaps = 9/80 (11%)

Query: 4   GFSPRGGGFGG------RGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGG 57
           G+S  GG  GG       GGFG  G RG  G  GGG    GGF G G GGG GGG GGG 
Sbjct: 70  GYSYGGGSGGGFSASSLGGGFGG-GSRGFGGASGGGYSSSGGFGG-GFGGGSGGGFGGGY 127

Query: 58  GRGGGGFHS-GGNRGRGRGG 76
           G G GGF   GG  G G GG
Sbjct: 128 GSGFGGFGGFGGGAGGGDGG 147



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 37/76 (48%), Positives = 39/76 (51%), Gaps = 3/76 (3%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRG--GGGGGGGGGGGGRGGGGFHS 66
           GGG  G  G    GG G  GG GGG G G G RG   G  GGG G GG  GG  GGG  +
Sbjct: 547 GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEA 606

Query: 67  GGNRGRGRGGKRGNQS 82
            G+ G G GG  G  S
Sbjct: 607 SGS-GGGYGGGSGKSS 621



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 34/73 (46%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 10  GGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGN 69
           GG GG  G G   G G  GG+GGG G  GG  G   GGG G GG  GG  GGG   SG  
Sbjct: 552 GGSGGNYGGGSGSGGGSGGGYGGGSGSRGG-SGGSHGGGSGFGGESGGSYGGGEEASGSG 610

Query: 70  RGRGRGGKRGNQS 82
            G G G  + + S
Sbjct: 611 GGYGGGSGKSSHS 623



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 39/80 (48%), Positives = 40/80 (50%), Gaps = 13/80 (16%)

Query: 13  GGRGGFGDRG----GRGGRGGFGGGRGRGG-GFRGRGRGGGGGGGG--------GGGGGR 59
           GG+  F   G    G GGRGG GG  GRG  G  G   GGGG GGG        GG GG 
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS 519

Query: 60  GGGGFHSGGNRGRGRGGKRG 79
            GGG  SGG  G G GG  G
Sbjct: 520 YGGGSGSGGGSGGGYGGGSG 539



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 41/87 (47%), Positives = 43/87 (49%), Gaps = 13/87 (14%)

Query: 9   GGGFGGRGGFGDRGGRGGR-------GGFGGG-RG----RGGGFRGRGRGGGGGGGGGGG 56
           G G GG  G+   GG GG        GGFGGG RG     GGG+   G  GGG GGG GG
Sbjct: 62  GRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGG 121

Query: 57  GGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           G  GG G   GG  G G GG  G   G
Sbjct: 122 GFGGGYGSGFGGFGGFG-GGAGGGDGG 147



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 31/63 (49%), Positives = 31/63 (49%), Gaps = 5/63 (7%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGG-----GGGGGGGRGGGG 63
           G G GG  G G  GG G RGG GG  G G GF G   G  GGG      GGG GG  G  
Sbjct: 561 GSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKS 620

Query: 64  FHS 66
            HS
Sbjct: 621 SHS 623



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 40/85 (47%), Positives = 40/85 (47%), Gaps = 8/85 (9%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGG-----GGGG 58
           G S R  G GG G FG   G G  GGF      GGGF G  RG GG  GGG     G GG
Sbjct: 55  GGSSRVCGRGGGGSFGYSYGGGSGGGFSAS-SLGGGFGGGSRGFGGASGGGYSSSGGFGG 113

Query: 59  RGGGGFHSGGNRGRGRGGKRGNQSG 83
             GGG  SGG  G G G   G   G
Sbjct: 114 GFGGG--SGGGFGGGYGSGFGGFGG 136



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 36/79 (45%), Positives = 37/79 (46%), Gaps = 9/79 (11%)

Query: 9  GGGFGGRGG-------FGDRGGRGGRGGFGGGRGRGGGF-RGRGRGGGGGGGGGGGGGRG 60
          GGG G  G        F   GG GG G F    G GGG  R  GRGGGG  G   GGG  
Sbjct: 19 GGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGG-S 77

Query: 61 GGGFHSGGNRGRGRGGKRG 79
          GGGF +    G   GG RG
Sbjct: 78 GGGFSASSLGGGFGGGSRG 96



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 32/61 (52%), Positives = 32/61 (52%), Gaps = 6/61 (9%)

Query: 4   GFSPRGGGFGGR--GGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGG 61
           G S  GGG GG   GG G RGG GG    GGG G GG     G  GGG    G GGG GG
Sbjct: 560 GGSGSGGGSGGGYGGGSGSRGGSGG--SHGGGSGFGG--ESGGSYGGGEEASGSGGGYGG 615

Query: 62  G 62
           G
Sbjct: 616 G 616



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 27/59 (45%), Positives = 29/59 (49%), Gaps = 3/59 (5%)

Query: 28 GGFGGGRGRGGGFRGR-GRGGGGGGGGGGGGGRGGGGFHSGGNR--GRGRGGKRGNQSG 83
          GG GGG G GG  R    R    GGGGGGG      G+  G +R  GRG GG  G   G
Sbjct: 16 GGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYG 74



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/68 (42%), Positives = 31/68 (45%), Gaps = 13/68 (19%)

Query: 21 RGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGG--------GGGG----GRGGGGFHSGG 68
          R G GG GG G G      +      GGGGGGG        GGG     GRGGGG   G 
Sbjct: 13 RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGG-SFGY 71

Query: 69 NRGRGRGG 76
          + G G GG
Sbjct: 72 SYGGGSGG 79



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 24/51 (47%), Positives = 27/51 (52%), Gaps = 7/51 (13%)

Query: 40  FRGRGRG----GGGGGGGG--GGGGRGG-GGFHSGGNRGRGRGGKRGNQSG 83
           F   G G    GG GG GG  G G RGG GG + GG  G G GG  G++ G
Sbjct: 465 FESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG 515


>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
           [Homo sapiens]
          Length = 372

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 44/75 (58%), Positives = 48/75 (64%), Gaps = 4/75 (5%)

Query: 8   RGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSG 67
           RGGGFGG   FG  G   GRGGFGG RG GGG+ G G G  G G  GG GG G G  +SG
Sbjct: 206 RGGGFGGNDNFGRGGNFSGRGGFGGSRG-GGGYGGSGDGYNGFGNDGGYGGGGPG--YSG 262

Query: 68  GNRGRGRGGK-RGNQ 81
           G+RG G GG+  GNQ
Sbjct: 263 GSRGYGSGGQGYGNQ 277



 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 43/81 (53%), Positives = 46/81 (56%), Gaps = 9/81 (11%)

Query: 8   RGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGG--GGGRG-GGGF 64
           RGG F GRGGFG  G RGG GG+GG    G G+ G G  GG GGGG G  GG RG G G 
Sbjct: 218 RGGNFSGRGGFG--GSRGG-GGYGGS---GDGYNGFGNDGGYGGGGPGYSGGSRGYGSGG 271

Query: 65  HSGGNRGRGRGGKRGNQSGKN 85
              GN+G G GG     S  N
Sbjct: 272 QGYGNQGSGYGGSGSYDSYNN 292



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 43/94 (45%), Positives = 48/94 (51%), Gaps = 15/94 (15%)

Query: 4   GFSPRGGGFGGRG----GFGDRGGRGGRG-GF-GGGRGRGGGFRGRGRGGGGGGG----- 52
           G S  GGG+GG G    GFG+ GG GG G G+ GG RG G G +G G  G G GG     
Sbjct: 229 GGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYD 288

Query: 53  ----GGGGGGRGGGGFHSGGNRGRGRGGKRGNQS 82
               GGGGG  GG G + GG       G   NQS
Sbjct: 289 SYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQS 322



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 33/94 (35%), Positives = 43/94 (45%), Gaps = 13/94 (13%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGR----GGGFRGRGR-----GGGGGGGGG 54
           G+  +G G+GG G + D    GG GGFGGG G     GG +   G         G   GG
Sbjct: 273 GYGNQGSGYGGSGSY-DSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGG 331

Query: 55  GGGGRGGGGFHSGGN---RGRGRGGKRGNQSGKN 85
             GGR  G +  GG    + R +GG  G+ S  +
Sbjct: 332 NFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSS 365



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 20/41 (48%), Positives = 22/41 (53%)

Query: 43  RGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           RGR G G  GGG GGG GG      G    GRGG  G++ G
Sbjct: 194 RGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG 234



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 26/65 (40%), Positives = 27/65 (41%), Gaps = 16/65 (24%)

Query: 23  GRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRG--RGRGGKRGN 80
           GR G G FGGGRG              GG GG      GG F   G  G  RG GG  G+
Sbjct: 195 GRSGSGNFGGGRG--------------GGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS 240

Query: 81  QSGKN 85
             G N
Sbjct: 241 GDGYN 245


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 45/87 (51%), Positives = 47/87 (54%), Gaps = 13/87 (14%)

Query: 8   RGGGFGGR-----------GGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGG 56
           R GGFGG            GGFG   G G  GGFGGGRG GGGF G G  GG GG GG G
Sbjct: 76  RAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAG 135

Query: 57  GGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           G  G GGF  GG+ G G  G  G+  G
Sbjct: 136 GFGGPGGF--GGSGGFGGPGSLGSPGG 160



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 38/75 (50%), Positives = 39/75 (52%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGG 68
           GGGFG   G G  GG GG  G GGG G  GGF G G  GG GG GG GG  G GGF   G
Sbjct: 94  GGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPG 153

Query: 69  NRGRGRGGKRGNQSG 83
           + G   G   G   G
Sbjct: 154 SLGSPGGFGPGGFPG 168



 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 36/59 (61%), Positives = 36/59 (61%), Gaps = 5/59 (8%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSG 67
           GGGFGG GGFG  GG GG GGFGG     GGF G G G GG G  G  GG G GGF  G
Sbjct: 116 GGGFGGAGGFGGAGGFGGAGGFGG----PGGFGGSG-GFGGPGSLGSPGGFGPGGFPGG 169



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 44/106 (41%), Positives = 46/106 (43%), Gaps = 34/106 (32%)

Query: 10  GGFGGRGGFGDRGGRGG-------------------------RGGFGGGR-------GRG 37
           GG GG G +G R G GG                          GGFGGGR       G G
Sbjct: 36  GGAGG-GAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYG 94

Query: 38  GGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           GGF G G GGG GGG GGG G GGG   +GG  G G  G  G   G
Sbjct: 95  GGF-GSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGG 139



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 41/96 (42%), Positives = 45/96 (46%), Gaps = 20/96 (20%)

Query: 6   SPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGG-----GGGGGGGGGGRG 60
           S   GG+GG  G G  GG GG  GF  G G G GF GRG GGG     GGG  G  GG G
Sbjct: 532 SASAGGYGGGYGGGMGGGLGG--GFSAGGGSGSGF-GRGGGGGIGGGFGGGSSGFSGGSG 588

Query: 61  ------------GGGFHSGGNRGRGRGGKRGNQSGK 84
                       GGGF S  NRG      + +QS +
Sbjct: 589 FGSISGARYGVSGGGFSSASNRGGSIKFSQSSQSSQ 624



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 48/116 (41%), Positives = 52/116 (44%), Gaps = 30/116 (25%)

Query: 4   GFSPRGGGFGGRGGFGDRGGR---------GGR-GGFGGGR-------GRGGGFRGRGRG 46
           GF    GGFG R  +   G +         G R GGFGGGR       G GGGF G G G
Sbjct: 44  GFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGF-GSGYG 102

Query: 47  GGGGGGGGGG-------GGRGG----GGF-HSGGNRGRGRGGKRGNQSGKNVMVEP 90
           GG GGG GGG       GG GG    GGF  +GG  G G  G  G   G   +  P
Sbjct: 103 GGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSP 158



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 29/50 (58%), Positives = 29/50 (58%), Gaps = 6/50 (12%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFG--GGRGRGGGFRGRGRGGGGGG 51
           GF   G GFGG GGFG  GG GG GGFG  G  G  GGF   G GG  GG
Sbjct: 124 GFGGAG-GFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGF---GPGGFPGG 169



 Score = 32.0 bits (71), Expect = 0.76
 Identities = 17/31 (54%), Positives = 17/31 (54%), Gaps = 1/31 (3%)

Query: 3   PGFSPRGGGFGGRGGFGDRGGRGGRGGFGGG 33
           PG     GGFGG G  G  GG  G GGF GG
Sbjct: 140 PGGFGGSGGFGGPGSLGSPGG-FGPGGFPGG 169



 Score = 32.0 bits (71), Expect = 0.76
 Identities = 16/37 (43%), Positives = 18/37 (48%)

Query: 50  GGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNV 86
           GG GGG GG  GGG   G + G G G   G   G  +
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGI 572



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 26/76 (34%), Positives = 28/76 (36%), Gaps = 23/76 (30%)

Query: 28 GGFGGGRGRGGGFRGRGR----GGGGGGGGGGGGGR-GGGGFHS---------------- 66
          GG  G  GR     G  R       GG GGG  G R G GGF S                
Sbjct: 11 GGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISV 70

Query: 67 --GGNRGRGRGGKRGN 80
            GG+R  G GG R +
Sbjct: 71 AAGGSRAGGFGGGRSS 86


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 47/92 (51%), Positives = 48/92 (52%), Gaps = 21/92 (22%)

Query: 9   GGGFGGRGGFGDR------------------GGRGGR--GGFGGGRGRGGGFRGRGRGGG 48
           GG FG  GGFG R                  GGRG    GG+GGG   GGGF G G GGG
Sbjct: 53  GGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGG 112

Query: 49  G-GGGGGGGGGRGGGGFHSGGNRGRGRGGKRG 79
           G GGGG GG G GGGGF  GG  G G GG  G
Sbjct: 113 GIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYG 144



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 43/100 (43%), Positives = 49/100 (49%), Gaps = 12/100 (12%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGR---------GRGGGGGGGGGGGGGR 59
           GGG GGRG +G  G   G GG   G G GGG  G           RGG GGGGGG  GGR
Sbjct: 543 GGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGR 602

Query: 60  GGGGFHSGGN---RGRGRGGKRGNQSGKNVMVEPHRHEGV 96
           G GG  SGG+   RG   GG + +    +V      + GV
Sbjct: 603 GSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGV 642



 Score = 71.6 bits (174), Expect = 9e-13
 Identities = 43/89 (48%), Positives = 45/89 (50%), Gaps = 8/89 (8%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGR-----GGFGGGRGR---GGGFRGRGRGGGGGGGGGG 55
           G   RGGG GG G  G   G GG      GG GGGRG    GG   G G G  G GGGGG
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGG 573

Query: 56  GGGRGGGGFHSGGNRGRGRGGKRGNQSGK 84
           G G  G G  SGG RG   GG  G+  G+
Sbjct: 574 GHGSYGSGSSSGGYRGGSGGGGGGSSGGR 602



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 37/61 (60%), Positives = 38/61 (62%), Gaps = 1/61 (1%)

Query: 8   RGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGG-GGGGRGGGGFHS 66
           RGGG G   G G  GG  G GGFGGG   GGG  G G GG G GGGG GGGG GGGG+  
Sbjct: 82  RGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGG 141

Query: 67  G 67
           G
Sbjct: 142 G 142



 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 39/83 (46%), Positives = 42/83 (50%), Gaps = 9/83 (10%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGG-------GGRGG 61
           GG +G  GG G  GGRG  G  G   G GGG  G G GGGG G  G G       GG GG
Sbjct: 536 GGSYGSGGGGG--GGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGG 593

Query: 62  GGFHSGGNRGRGRGGKRGNQSGK 84
           GG  S G RG G G   G+  G+
Sbjct: 594 GGGGSSGGRGSGGGSSGGSIGGR 616



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 42/82 (51%), Positives = 42/82 (51%), Gaps = 16/82 (19%)

Query: 8   RGGGFGGRGGFGDRGGRGGRGGFGGGRGR------GGG-------FRGRGRGGGGGGGGG 54
           R GG GGR  F   GG GG  G GGG G       GG         RG GRG G GGG G
Sbjct: 38  RSGGGGGR--FSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYG 95

Query: 55  GGGGRGGGGFHSGGNRGRGRGG 76
           GGG  GGGGF  GG  G G GG
Sbjct: 96  GGGF-GGGGFGGGGFGGGGIGG 116



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 23/37 (62%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGF 40
           GF   G G GG GGFG  GG  G GGFGGG G GGG+
Sbjct: 108 GFGGGGIGGGGFGGFGSGGGGFGGGGFGGG-GYGGGY 143



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 2/52 (3%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGG 55
           G     GG+ G  G G  G  GGRG   GG   GG   GRG   GG    GG
Sbjct: 579 GSGSSSGGYRGGSGGGGGGSSGGRG--SGGGSSGGSIGGRGSSSGGVKSSGG 628



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 32/91 (35%), Positives = 34/91 (37%), Gaps = 29/91 (31%)

Query: 18 FGDRGGRGGRGGFGGGRGRGGGFRGRG------RGGGGGG-----GGGGGGGRGGGGFHS 66
          F  R G    GGF  G      ++ R       R GGGGG     GGGGG    GGGF S
Sbjct: 5  FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGS 64

Query: 67 ------------------GGNRGRGRGGKRG 79
                            GG RG G GG  G
Sbjct: 65 RSLVNLGGSKSISISVARGGGRGSGFGGGYG 95


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 42/60 (70%), Positives = 43/60 (71%), Gaps = 7/60 (11%)

Query: 7   PRG-GGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFH 65
           P+G GGFGGRGG     GRGG GG GGGRG  GGF GRGR GG GG GG  GGRGGGG H
Sbjct: 647 PKGEGGFGGRGG-----GRGGFGGRGGGRGGRGGFGGRGR-GGFGGRGGFRGGRGGGGDH 700



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 36/69 (52%), Positives = 39/69 (56%), Gaps = 10/69 (14%)

Query: 14  GRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRG 73
           G GGFG RGG  GRGGFGG        RG GRGG GG GG G GG GG G   GG  G G
Sbjct: 649 GEGGFGGRGG--GRGGFGG--------RGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGG 698

Query: 74  RGGKRGNQS 82
               +G ++
Sbjct: 699 DHKPQGKKT 707



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 36/62 (58%), Positives = 36/62 (58%), Gaps = 4/62 (6%)

Query: 23  GRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQS 82
           G GG GG GGGR   GGF GRG GG GG GG GG GRGG G   G   GRG GG    Q 
Sbjct: 649 GEGGFGGRGGGR---GGFGGRG-GGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQG 704

Query: 83  GK 84
            K
Sbjct: 705 KK 706



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 29/44 (65%), Positives = 32/44 (72%), Gaps = 2/44 (4%)

Query: 4   GFSPRGGGFGGRGGFG--DRGGRGGRGGFGGGRGRGGGFRGRGR 45
           GF  RGGG GGRGGFG   RGG GGRGGF GGRG GG  + +G+
Sbjct: 662 GFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGK 705



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 24/39 (61%), Positives = 25/39 (64%)

Query: 41  RGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRG 79
           +G G  GG GGG GG GGRGGG    GG  GRGRGG  G
Sbjct: 648 KGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGG 686



 Score = 29.3 bits (64), Expect = 4.9
 Identities = 14/27 (51%), Positives = 16/27 (59%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGF 30
           GF  RGG  GGRGG GD   +G +  F
Sbjct: 683 GFGGRGGFRGGRGGGGDHKPQGKKTKF 709


>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
           sapiens]
          Length = 378

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 46/91 (50%), Positives = 50/91 (54%), Gaps = 19/91 (20%)

Query: 8   RGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRG-----------RGGGGGGG---G 53
           RGG FGGRGG+G  GG G RG +GGG G   GF G G           RGG GGGG   G
Sbjct: 239 RGGNFGGRGGYGGGGG-GSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYG 297

Query: 54  GGGGGRGGG----GFHSGGNRGRGRGGKRGN 80
             GGG GGG    G++ GGN G G  G  GN
Sbjct: 298 NQGGGYGGGGGYDGYNEGGNFGGGNYGGGGN 328



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 43/80 (53%), Positives = 45/80 (56%), Gaps = 2/80 (2%)

Query: 5   FSPRGGGFGGRGG-FGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGG 63
           F  RGG FGG GG FG  G  GGRGG+GGG G   G  G G GG  G GG GG   GG G
Sbjct: 223 FMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPG 282

Query: 64  FHSGGNRGRGRGGKRGNQSG 83
           + S G  G G G   GNQ G
Sbjct: 283 YSSRGGYG-GGGPGYGNQGG 301



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 42/80 (52%), Positives = 43/80 (53%), Gaps = 4/80 (5%)

Query: 8   RGGGFG---GRGG-FGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGG 63
           RGGG G   GRGG FG  GG  GRGG  GGRG  GG  G  RG  GGG GG  G  G GG
Sbjct: 216 RGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGG 275

Query: 64  FHSGGNRGRGRGGKRGNQSG 83
            + GG     RGG  G   G
Sbjct: 276 NYGGGPGYSSRGGYGGGGPG 295



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 40/87 (45%), Positives = 47/87 (54%), Gaps = 8/87 (9%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRG-GFG---GGRGRGGGFRGRGRGGGGGGGG-GGGGG 58
           GF   GG +GG  G+  RGG GG G G+G   GG G GGG+ G   GG  GGG  GGGG 
Sbjct: 269 GFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGN 328

Query: 59  RGGGGFHSG---GNRGRGRGGKRGNQS 82
               G +SG    N G  +GG  G +S
Sbjct: 329 YNDFGNYSGQQQSNYGPMKGGSFGGRS 355



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 46/88 (52%), Positives = 47/88 (53%), Gaps = 8/88 (9%)

Query: 1   MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGR--GGGGGGGGGGGGG 58
           M+   S RG G GG G F  RGG  G GG  G  GRGG F GRG   GGGGG  G  GGG
Sbjct: 207 MQSAGSQRGRG-GGSGNFMGRGGNFGGGG--GNFGRGGNFGGRGGYGGGGGGSRGSYGGG 263

Query: 59  RGG-GGF-HSGGNRGRGRG-GKRGNQSG 83
            GG  GF   GGN G G G   RG   G
Sbjct: 264 DGGYNGFGGDGGNYGGGPGYSSRGGYGG 291



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 39/98 (39%), Positives = 45/98 (45%), Gaps = 23/98 (23%)

Query: 3   PGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGG------------ 50
           PG+S RGG  GG  G+G++GG  G GG   G   GG F G   GGGG             
Sbjct: 281 PGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQ 340

Query: 51  -------GGGGGGGGRG---GGGFHSGGNRGRGRGGKR 78
                  GG  GG   G   GGG+ SGG  G G G +R
Sbjct: 341 SNYGPMKGGSFGGRSSGSPYGGGYGSGGGSG-GYGSRR 377


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 43/93 (46%), Positives = 52/93 (55%), Gaps = 14/93 (15%)

Query: 5   FSPRGGGFGGRGGFGDRG--------GRGGRGGFG----GGRGRGGGFRGRGRGGGGGGG 52
           ++   GG GG GG G+ G        G G  GG+G     G G  GG+  + RGG G GG
Sbjct: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGG 220

Query: 53  GGGGGGRGGGGFH--SGGNRGRGRGGKRGNQSG 83
            GGGGG GGGG++  SGG   RGRGG RG + G
Sbjct: 221 SGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGG 253



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 42/91 (46%), Positives = 49/91 (53%), Gaps = 13/91 (14%)

Query: 11  GFGGRGGFG--DRGGRGGRGGFGGGRGRG--------GGFRGRGRGGGGGGGGGGGGGRG 60
           G GG GG+G  DRGGRG RGG GGG G G        GG+  RGRGGG GG GG GG   
Sbjct: 201 GGGGSGGYGQQDRGGRG-RGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDR 259

Query: 61  GGGFHSGGNRGRG--RGGKRGNQSGKNVMVE 89
           GG    GG R +G     ++ N     + V+
Sbjct: 260 GGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQ 290



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 47/108 (43%), Positives = 48/108 (44%), Gaps = 43/108 (39%)

Query: 8   RGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGG---------- 57
           RGGG  GRGG G RGG  GRGG+GGG G GGG    GRGG   GGGGGGG          
Sbjct: 377 RGGG-NGRGGRG-RGGPMGRGGYGGG-GSGGG----GRGGFPSGGGGGGGQQRAGDWKCP 429

Query: 58  --------------------------GRGGGGFHSGGNRGRGRGGKRG 79
                                     G G GG H GGN G  R G RG
Sbjct: 430 NPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRG 477



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 44/112 (39%), Positives = 50/112 (44%), Gaps = 38/112 (33%)

Query: 10  GGFGGRGGFGDRG-GRGGRGGF------GGGRGRGGGFR--------------------- 41
           GG  GRGG+G  G G GGRGGF      GGG+ R G ++                     
Sbjct: 389 GGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCK 448

Query: 42  -------GRGRGGGGGGGGGGGGGRGG-GGFHSGGNRGRG--RGGKRGNQSG 83
                  G G GG   GG  G   RGG GG+  GG RGRG  RGG RG + G
Sbjct: 449 APKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGG 500



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 34/76 (44%), Positives = 37/76 (48%), Gaps = 8/76 (10%)

Query: 3   PGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGG 62
           PG  P G   GG  G   RGGRGG           GG+RGRG   GG  GG GGG RGG 
Sbjct: 455 PGGGPGGSHMGGNYGDDRRGGRGGYDR--------GGYRGRGGDRGGFRGGRGGGDRGGF 506

Query: 63  GFHSGGNRGRGRGGKR 78
           G     +RG  R  +R
Sbjct: 507 GPGKMDSRGEHRQDRR 522



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 34/63 (53%), Positives = 36/63 (57%), Gaps = 10/63 (15%)

Query: 12  FGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRG 71
           F  R    +RGG  GR    GGRGRGG     GRGG GGGG GGG   G GGF SGG  G
Sbjct: 368 FATRRADFNRGGGNGR----GGRGRGGPM---GRGGYGGGGSGGG---GRGGFPSGGGGG 417

Query: 72  RGR 74
            G+
Sbjct: 418 GGQ 420



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 44/101 (43%), Positives = 46/101 (45%), Gaps = 23/101 (22%)

Query: 9   GGGFGG-----RGGFGDRGGRGGRGGFGGG-----------RGRGGGFRGRGRGGGGGGG 52
           GGG GG     RGG G RGG GG GG GGG           RGRGGG RG GRGG GG  
Sbjct: 202 GGGSGGYGQQDRGGRG-RGGSGGGGGGGGGGYNRSSGGYEPRGRGGG-RG-GRGGMGGSD 258

Query: 53  GGG----GGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVE 89
            GG    GG R  G  H                 G+NV +E
Sbjct: 259 RGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIE 299



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 39/120 (32%), Positives = 41/120 (34%), Gaps = 44/120 (36%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGR------------------------------------ 27
           G+   G G GGRGGF   GG GG                                     
Sbjct: 396 GYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGP 455

Query: 28  -GGFGG-------GRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRG 79
            GG GG       G  R GG  G  RGG  G GG  GG RGG G    G  G G+   RG
Sbjct: 456 GGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRG 515



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 26/103 (25%)

Query: 7   PRGGGFGGRGGFG-DRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGG--------- 56
           P+ G +  +  +G  +   G +  +   +G G   +     GGGGGGGGGG         
Sbjct: 125 PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSM 184

Query: 57  ---GGRGG--------GGFHSGG-----NRGRGRGGKRGNQSG 83
              GG GG        GG  SGG       GRGRGG  G   G
Sbjct: 185 SSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG 227



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 20/42 (47%), Positives = 25/42 (59%), Gaps = 1/42 (2%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFG-GGRGRGGGFRGRG 44
           G++   GG+  RG  G RGGRGG GG   GG  + GG R +G
Sbjct: 231 GYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG 272


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 40/80 (50%), Positives = 42/80 (52%), Gaps = 5/80 (6%)

Query: 9   GGGFGGRGG-----FGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGG 63
           GGG GG GG     FG  G  GG  G G G   GGG+ G G GGG  GGGGGGG  G GG
Sbjct: 23  GGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGG 82

Query: 64  FHSGGNRGRGRGGKRGNQSG 83
              G  +  G GG  G  SG
Sbjct: 83  GSGGSVKYSGGGGSSGGGSG 102



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 40/68 (58%), Positives = 40/68 (58%), Gaps = 6/68 (8%)

Query: 13 GGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRG--GGGG--GGGGGGGGRGGGGFHSGG 68
          GG GG G  GG GG G FGGG G GGG  G G G  GGGG  GGG GGG  GGGG    G
Sbjct: 21 GGGGGGGGSGG-GGCGFFGGG-GSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG 78

Query: 69 NRGRGRGG 76
            G G GG
Sbjct: 79 GCGGGSGG 86



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 39/84 (46%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGG----GGGGGGR 59
           G S  GGG GG GG G  GG GG   + GG G  GG  G    GGGG G    GGGG   
Sbjct: 66  GGSSGGGGGGGIGGCG--GGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSG 123

Query: 60  GGGGFHSGGNRGRGRGGKRGNQSG 83
           GG G  S G  G   GG     SG
Sbjct: 124 GGSGCFSSGGGGSSGGGSGCFSSG 147



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 43/91 (47%), Positives = 44/91 (48%), Gaps = 17/91 (18%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGG----GGGGGG-----GGGGR 59
           GGG  G G  G   G  G GG+ GG G GGG  G G GGG    GGG GG     GGGG 
Sbjct: 38  GGGGSGGGSSGSGCGYSGGGGYSGG-GCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGS 96

Query: 60  GGGG---FHSGGNR----GRGRGGKRGNQSG 83
            GGG   F SGG        G GG  G  SG
Sbjct: 97  SGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 43/98 (43%), Positives = 46/98 (46%), Gaps = 18/98 (18%)

Query: 4   GFSPRGGGFGGRGGF---GDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGG------ 54
           G S  G G+ G GG+   G  GG  G GG GG  G GGG  G  +  GGGG  G      
Sbjct: 45  GSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCF 104

Query: 55  --GGGGRG----GGGFHSGGNRG---RGRGGKRGNQSG 83
             GGGG G    GGG  SGG  G    G GG  G  SG
Sbjct: 105 SSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSG 142



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 41/99 (41%), Positives = 42/99 (42%), Gaps = 22/99 (22%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGF-GGGRGRGGGFRGRGRGGG-------------- 48
           G S  G   GG G F   GG G   G+ GGG G GGG  G G G G              
Sbjct: 163 GVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSG-GSGSGYVSSQQVTQTSCAP 221

Query: 49  ----GGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
               GGG  GGGG  G G F SGG  G G  G  G  SG
Sbjct: 222 QPSYGGGSSGGGGSGGSGCFSSGG--GGGSSGCGGGSSG 258



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 34/72 (47%), Positives = 36/72 (50%), Gaps = 7/72 (9%)

Query: 22 GGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGG----GGGGRGGGGFHSGGNRGRGRGGK 77
          GG GG GG GGG   G GF G G  GGG  G G    GGGG  GGG   G + G G GG 
Sbjct: 21 GGGGGGGGSGGG---GCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGI 77

Query: 78 RGNQSGKNVMVE 89
           G   G    V+
Sbjct: 78 GGCGGGSGGSVK 89



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 35/71 (49%), Positives = 37/71 (52%), Gaps = 6/71 (8%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRG----GGGGGGGGGGGGRGGGGF 64
           GGG  G GG G  G     GG GG  G GGG  G G G    GGG   GGG  G GGGG 
Sbjct: 226 GGGSSGGGGSGGSGCFSSGGG-GGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGS 284

Query: 65  HSGGNRGRGRG 75
             GG+ G G+G
Sbjct: 285 SVGGS-GSGKG 294



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 31/68 (45%), Positives = 32/68 (47%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGG 63
           G S  GGG GG G F   GG G  G  GG  G G G    G G   GGG  GGGG G   
Sbjct: 227 GGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSV 286

Query: 64  FHSGGNRG 71
             SG  +G
Sbjct: 287 GGSGSGKG 294



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 39/94 (41%), Positives = 42/94 (44%), Gaps = 15/94 (15%)

Query: 5   FSPRGGGF--GGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRG-----RGGGGGGGGGGGG 57
           FS  GGG   GG G F   GG    GG G     GGGF G+       GG   GG  GGG
Sbjct: 114 FSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGG 173

Query: 58  ------GRGGGGF--HSGGNRGRGRGGKRGNQSG 83
                 G GGG    +SGG  G G G   G+ SG
Sbjct: 174 SGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSG 207



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 38/87 (43%), Positives = 40/87 (45%), Gaps = 17/87 (19%)

Query: 5   FSPRGGGFGGRGGFGDRGGRGGRGGF--GGGRGRGGGFRGRGRGGGGGGGGG------GG 56
           +S  GG  GG  G    GG GG G F  GGG   GGG      GGGG  GGG      GG
Sbjct: 90  YSGGGGSSGGGSGCFSSGG-GGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGG 148

Query: 57  GGRGG--------GGFHSGGNRGRGRG 75
           GG  G        GG  SGG+ G G G
Sbjct: 149 GGFSGQAVQCQSYGGVSSGGSSGGGSG 175



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 40/114 (35%), Positives = 44/114 (38%), Gaps = 33/114 (28%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRG--------------------GRGGFGGGRGRGGGFRGR 43
           G+S  G G GG    G  GG G                    G G  GGG   G G    
Sbjct: 188 GYSGGGSGCGG----GSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSS 243

Query: 44  GRGGGGGGGGGGGGG-------RGGGGFHSGGNRGRGRGGKR--GNQSGKNVMV 88
           G GGG  G GGG  G        GGG    GG+ G G GG    G+ SGK V +
Sbjct: 244 GGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPI 297


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 42/81 (51%), Positives = 43/81 (53%), Gaps = 2/81 (2%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRG-GGFRGRGRGGGGGGGGGGGGGRGGG 62
           G S  GG  GG  G G  GG  G G  GGG G G GG  G G GGG  GGG  GGG GGG
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGG 516

Query: 63  GFHSGGNRGRGRGGKRGNQSG 83
              SGG+ G   GG  G  SG
Sbjct: 517 S-SSGGHGGSSSGGYGGGSSG 536



 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 41/79 (51%), Positives = 43/79 (54%), Gaps = 6/79 (7%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRG---GGFRGRGRGG-GGGGGGGGGGGRGGGGF 64
           GGG GG  G G  GG  G G  GGG G G   GG  G   GG GGG  GGGGGG GGG  
Sbjct: 488 GGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSS 547

Query: 65  HSGGNRGRGRGGKRGNQSG 83
             G + G G GG  G+ SG
Sbjct: 548 GGGSSSGGGYGG--GSSSG 564



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 41/80 (51%), Positives = 42/80 (52%), Gaps = 3/80 (3%)

Query: 5   FSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGG-GGGGGGGGGRGGGG 63
           F    GG+GG GGFG    RG  G    G   GG F G   GGG  GGG  GGGG GGGG
Sbjct: 67  FGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGG 126

Query: 64  FHSGGNRGRGRGGKRGNQSG 83
           F  GG  G G GG  G  SG
Sbjct: 127 F--GGGFGGGFGGDGGLLSG 144



 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 42/83 (50%), Positives = 45/83 (54%), Gaps = 8/83 (9%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRG--RGGGFRGRGRGGG--GGGGGGG--GGGRGG- 61
           GG FGG  G G  GG    GG GGG G   GGG+ G   GGG  GGG GGG   GG GG 
Sbjct: 466 GGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGS 525

Query: 62  -GGFHSGGNRGRGRGGKRGNQSG 83
             G + GG+ G G GG  G  SG
Sbjct: 526 SSGGYGGGSSGGGGGGYGGGSSG 548



 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 40/81 (49%), Positives = 43/81 (53%), Gaps = 6/81 (7%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGR---GRGGGFRGRGRGGGGGGGGGG-GGGRGGGGF 64
           GG  GG  G G  GG    GG+GGG    G GG   G   GG  GGGGGG GGG  GGG 
Sbjct: 492 GGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGS 551

Query: 65  HSGGNRGRG--RGGKRGNQSG 83
            SGG  G G   GG + + SG
Sbjct: 552 SSGGGYGGGSSSGGHKSSSSG 572



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 38/83 (45%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGR--GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGG 61
           G S  G   GG GG    GG GG   GG+GGG   GGG    G GGG  GGG   GG  G
Sbjct: 502 GSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGG---GGYGGGSSGGGSSSGGGYG 558

Query: 62  GGFHSGGNRGRGRGGKRGNQSGK 84
           GG  SGG++     G  G  S K
Sbjct: 559 GGSSSGGHKS-SSSGSVGESSSK 580



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 37/83 (44%), Positives = 38/83 (45%), Gaps = 9/83 (10%)

Query: 9   GGGFGG--RGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGG-------GGGGGGGGGR 59
           GGG+GG   GG    GG GG  G   G G GGG  G G  GGG       GG GG   G 
Sbjct: 470 GGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGG 529

Query: 60  GGGGFHSGGNRGRGRGGKRGNQS 82
            GGG   GG  G G G   G  S
Sbjct: 530 YGGGSSGGGGGGYGGGSSGGGSS 552



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 32/77 (41%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGG-GGGRGGG 62
           G    GGG+GG    G  GG    G  GG  G GGG  G G  GGG   GGG GGG   G
Sbjct: 505 GGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSG 564

Query: 63  GFHSGGNRGRGRGGKRG 79
           G  S  +   G    +G
Sbjct: 565 GHKSSSSGSVGESSSKG 581



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/87 (41%), Positives = 37/87 (42%), Gaps = 9/87 (10%)

Query: 6  SPRGGGFGGRGGFGDRGG------RGGRGGFGGGRGRGG---GFRGRGRGGGGGGGGGGG 56
          S R GG GG GG G  GG         +G  GGG   GG   G   RG  GGG  GG  G
Sbjct: 13 SSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSG 72

Query: 57 GGRGGGGFHSGGNRGRGRGGKRGNQSG 83
          G  G GGF  G  RG       G   G
Sbjct: 73 GYGGLGGFGGGSFRGSYGSSSFGGSYG 99



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 31/58 (53%), Positives = 32/58 (55%), Gaps = 7/58 (12%)

Query: 26  GRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           G G  GGG GRGGG      GGG GGG  GGG  GGG  H GG+ G   GG  G  SG
Sbjct: 455 GEGSSGGG-GRGGG----SFGGGYGGGSSGGGSSGGG--HGGGHGGSSGGGYGGGSSG 505



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 38/83 (45%), Positives = 39/83 (46%), Gaps = 15/83 (18%)

Query: 9   GGGFGGRGGF---------GDRGGRGGRGGFGGG---RGRGGG--FRGRGRGGGGGGGGG 54
           GGG GG GG          G  GG    GGF GG   RG  GG  F G   G GG GG G
Sbjct: 22  GGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFG 81

Query: 55  GGGGRGGGGFHS-GGNRGRGRGG 76
           GG  RG  G  S GG+ G   GG
Sbjct: 82  GGSFRGSYGSSSFGGSYGGSFGG 104



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 4/48 (8%)

Query: 40  FRGRGRGGGGGGGGGGGGGRGGGGF----HSGGNRGRGRGGKRGNQSG 83
           +R    G G  GGGG GGG  GGG+      GG+ G G GG  G  SG
Sbjct: 449 YRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSG 496



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 25/67 (37%), Positives = 27/67 (40%), Gaps = 14/67 (20%)

Query: 30 FGGGRGRGGGFRGRGRGGGGG-------------GGGGGGGGRGGGGFHSGGNRGRGRGG 76
          +   R  GGG  G G GGGGG             GGG   GG  GG F  G + G   GG
Sbjct: 11 YSSSRSGGGGGGG-GCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGG 69

Query: 77 KRGNQSG 83
            G   G
Sbjct: 70 SSGGYGG 76


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 46/94 (48%), Positives = 49/94 (52%), Gaps = 14/94 (14%)

Query: 6   SPRGGGFG------GRGGFGDRGG---RGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGG- 55
           S RGG FG      G G FG   G   RGG  G+G GRG G G+ G G G GGG  GG  
Sbjct: 201 SGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSP 260

Query: 56  --GGGRG--GGGFHSGGNRGRGRGGKRGNQSGKN 85
             GGGRG  GGG    GN+G G GG   N  G N
Sbjct: 261 GYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGN 294



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 41/106 (38%), Positives = 47/106 (44%), Gaps = 26/106 (24%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRG-RGGGFRGRGRGGGGGGGGGG------- 55
           G  P GG FGG  G+G  GGRGG GG G G G +GGG+ G     GGG  G G       
Sbjct: 248 GGGPGGGNFGGSPGYG--GGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGN 305

Query: 56  ----------------GGGRGGGGFHSGGNRGRGRGGKRGNQSGKN 85
                           GG R  GG + GGN G G  G  G   G++
Sbjct: 306 YNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRS 351



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 40/92 (43%), Positives = 46/92 (50%), Gaps = 11/92 (11%)

Query: 3   PGFSPRGG--GFGGRGGFGDR----GGRGGRGGFGGGRGRGGGFRGRGRGG---GGGGGG 53
           PG + RGG  G+G   GFGD     GG  G G FGG  G GGG  G G GG   G  GGG
Sbjct: 223 PGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGG 282

Query: 54  GGGG--GRGGGGFHSGGNRGRGRGGKRGNQSG 83
            GGG    GGG + SG     G   ++ +  G
Sbjct: 283 YGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYG 314



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 36/82 (43%), Positives = 37/82 (45%), Gaps = 19/82 (23%)

Query: 21  RGGRGGRGGFGGGRGRGGGF------------------RGRGRGGGGGGGGGGGGGRGGG 62
           R GRGG  GFG  RG GG F                  RG G G  G GGG GGG  GG 
Sbjct: 200 RSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGS 259

Query: 63  GFHSGGNRGRGRGGK-RGNQSG 83
             + GG  G G GG   GNQ G
Sbjct: 260 PGYGGGRGGYGGGGPGYGNQGG 281



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 36/93 (38%), Positives = 44/93 (47%), Gaps = 5/93 (5%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGG-GFRGRGRGGGGGGGGGGGGGRGGG 62
           GF     G+GG  G G+ GG  G GG  GG G GG G+  +G G GGG    GGG  G G
Sbjct: 239 GFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSG 298

Query: 63  GFHSGGNRGRGRGG----KRGNQSGKNVMVEPH 91
            ++  GN  +        K GN  G   M  P+
Sbjct: 299 NYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPY 331



 Score = 28.9 bits (63), Expect = 6.4
 Identities = 13/24 (54%), Positives = 14/24 (58%)

Query: 7   PRGGGFGGRGGFGDRGGRGGRGGF 30
           P GGG  G GG G  GG GGR  +
Sbjct: 330 PYGGGNYGPGGSGGSGGYGGRSRY 353


>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
           [Homo sapiens]
          Length = 341

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 46/94 (48%), Positives = 49/94 (52%), Gaps = 14/94 (14%)

Query: 6   SPRGGGFG------GRGGFGDRGG---RGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGG- 55
           S RGG FG      G G FG   G   RGG  G+G GRG G G+ G G G GGG  GG  
Sbjct: 189 SGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSP 248

Query: 56  --GGGRG--GGGFHSGGNRGRGRGGKRGNQSGKN 85
             GGGRG  GGG    GN+G G GG   N  G N
Sbjct: 249 GYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGN 282



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 41/106 (38%), Positives = 47/106 (44%), Gaps = 26/106 (24%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRG-RGGGFRGRGRGGGGGGGGGG------- 55
           G  P GG FGG  G+G  GGRGG GG G G G +GGG+ G     GGG  G G       
Sbjct: 236 GGGPGGGNFGGSPGYG--GGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGN 293

Query: 56  ----------------GGGRGGGGFHSGGNRGRGRGGKRGNQSGKN 85
                           GG R  GG + GGN G G  G  G   G++
Sbjct: 294 YNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRS 339



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 40/92 (43%), Positives = 46/92 (50%), Gaps = 11/92 (11%)

Query: 3   PGFSPRGG--GFGGRGGFGDR----GGRGGRGGFGGGRGRGGGFRGRGRGG---GGGGGG 53
           PG + RGG  G+G   GFGD     GG  G G FGG  G GGG  G G GG   G  GGG
Sbjct: 211 PGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGG 270

Query: 54  GGGG--GRGGGGFHSGGNRGRGRGGKRGNQSG 83
            GGG    GGG + SG     G   ++ +  G
Sbjct: 271 YGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYG 302



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 36/82 (43%), Positives = 37/82 (45%), Gaps = 19/82 (23%)

Query: 21  RGGRGGRGGFGGGRGRGGGF------------------RGRGRGGGGGGGGGGGGGRGGG 62
           R GRGG  GFG  RG GG F                  RG G G  G GGG GGG  GG 
Sbjct: 188 RSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGS 247

Query: 63  GFHSGGNRGRGRGGK-RGNQSG 83
             + GG  G G GG   GNQ G
Sbjct: 248 PGYGGGRGGYGGGGPGYGNQGG 269



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 36/93 (38%), Positives = 44/93 (47%), Gaps = 5/93 (5%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGG-GFRGRGRGGGGGGGGGGGGGRGGG 62
           GF     G+GG  G G+ GG  G GG  GG G GG G+  +G G GGG    GGG  G G
Sbjct: 227 GFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSG 286

Query: 63  GFHSGGNRGRGRGG----KRGNQSGKNVMVEPH 91
            ++  GN  +        K GN  G   M  P+
Sbjct: 287 NYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPY 319



 Score = 28.9 bits (63), Expect = 6.4
 Identities = 13/24 (54%), Positives = 14/24 (58%)

Query: 7   PRGGGFGGRGGFGDRGGRGGRGGF 30
           P GGG  G GG G  GG GGR  +
Sbjct: 318 PYGGGNYGPGGSGGSGGYGGRSRY 341


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 45/84 (53%), Positives = 45/84 (53%), Gaps = 11/84 (13%)

Query: 9   GGGFGGRGGFGDRG--GRGGR-------GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGR 59
           GGGFGG GGFG R   G GG         G GGG G  GGF GRG G GGG   GGG G 
Sbjct: 50  GGGFGG-GGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGF 108

Query: 60  GGGGFHSGGNRGRGRGGKRGNQSG 83
            GGGF  GG  G GR G  G   G
Sbjct: 109 SGGGF-GGGGFGGGRFGGFGGPGG 131



 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 51/96 (53%), Positives = 52/96 (54%), Gaps = 20/96 (20%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGR--GRGGGFRGRGRGGGGGGGG--GGGGGRGGGGF 64
           GGGFG  GGFG RGG     GFGGG   G G GF G G GGGG GGG  GG GG GG G 
Sbjct: 80  GGGFGAAGGFGGRGG-----GFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVG- 133

Query: 65  HSGGNRGRGRGGKRG-------NQS---GKNVMVEP 90
             GG  G G GG  G       NQS     NV V+P
Sbjct: 134 GLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDP 169



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 38/82 (46%), Positives = 42/82 (51%), Gaps = 5/82 (6%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG----GGGF 64
           GGG    GG+G  GG GGR G GGG  +GG   G G G GGG    GGG RG    GGG+
Sbjct: 554 GGGSISGGGYGSGGGSGGRYGSGGG-SKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGY 612

Query: 65  HSGGNRGRGRGGKRGNQSGKNV 86
            SGG       G  G   G +V
Sbjct: 613 GSGGGGSSSVKGSSGEAFGSSV 634



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 37/64 (57%), Positives = 38/64 (59%), Gaps = 2/64 (3%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGG 63
           GF  RGGGFGG   FG   G  G GGFGGG   GG F G G G GG GG GG GG G GG
Sbjct: 88  GFGGRGGGFGGGSSFGGGSGFSG-GGFGGGGFGGGRFGGFG-GPGGVGGLGGPGGFGPGG 145

Query: 64  FHSG 67
           +  G
Sbjct: 146 YPGG 149



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 46/98 (46%), Positives = 50/98 (51%), Gaps = 14/98 (14%)

Query: 6   SPRGGGFG------GRGG--FGDRGGRGGRGGF-GGGRGRGGGFRGR-GRGGGGGGGGGG 55
           S  GGG+       G GG   G RGG GG G   GGG G GGG  GR G GGG  GG   
Sbjct: 526 SSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSIS 585

Query: 56  GGGRG-GGGFHSGGNRGRG---RGGKRGNQSGKNVMVE 89
           GGG G GGG HS G   RG    GG  G+  G +  V+
Sbjct: 586 GGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVK 623



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 41/89 (46%), Positives = 44/89 (49%), Gaps = 16/89 (17%)

Query: 10  GGFGGRGGFGDRG--------GRGGR-GGFGGGRGRGGGFRGRGRGGGGG-GG--GGGGG 57
           GG GGRG     G        G GGR  G  GG G GG   G G G GGG GG  G GGG
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578

Query: 58  GRG----GGGFHSGGNRGRGRGGKRGNQS 82
            +G    GGG+ SGG +    GG RG  S
Sbjct: 579 SKGGSISGGGYGSGGGKHSSGGGSRGGSS 607



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 32/68 (47%), Positives = 33/68 (48%)

Query: 16  GGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRG 75
           GG G RG   G G   G    G G R  G  GG GGGG   GG  G G  SGG  G G G
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578

Query: 76  GKRGNQSG 83
            K G+ SG
Sbjct: 579 SKGGSISG 586



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 37/83 (44%), Positives = 38/83 (45%), Gaps = 14/83 (16%)

Query: 6   SPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGG---GGGGGGGGGRGGG 62
           S  GGG GG GG    GG G R   G G  +       G GGG    GG GG GGG GGG
Sbjct: 44  SRHGGGGGGFGG----GGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGG 99

Query: 63  -------GFHSGGNRGRGRGGKR 78
                  GF  GG  G G GG R
Sbjct: 100 SSFGGGSGFSGGGFGGGGFGGGR 122



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 37/94 (39%), Positives = 38/94 (40%), Gaps = 24/94 (25%)

Query: 8   RGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGG---------- 57
           RGGG GG  GF      G     GG R     F    R GGGGGG GGGG          
Sbjct: 12  RGGGGGGFRGFSS----GSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLG 67

Query: 58  ---------GRGGGGFHSGGNRGRGRGGKRGNQS 82
                      GGGGF + G  G GRGG  G  S
Sbjct: 68  GTKSISISVAGGGGGFGAAGGFG-GRGGGFGGGS 100



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 24/52 (46%), Positives = 26/52 (50%), Gaps = 3/52 (5%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGF--GGGRGRGGGFRGRGRGGGGGGGG 53
           G S  GGG+G  GG    GG G RGG   GGG G GGG     +G  G   G
Sbjct: 581 GGSISGGGYGSGGGKHSSGG-GSRGGSSSGGGYGSGGGGSSSVKGSSGEAFG 631



 Score = 36.6 bits (83), Expect = 0.031
 Identities = 28/87 (32%), Positives = 30/87 (34%), Gaps = 44/87 (50%)

Query: 41 RGRGRGGGGGG---------------------------GGGGGGGRGGGGFHS------- 66
          + RGRGGGGGG                            GGGGGG GGGGF S       
Sbjct: 8  KSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLG 67

Query: 67 ----------GGNRGRGRGGKRGNQSG 83
                    GG  G G  G  G + G
Sbjct: 68 GTKSISISVAGGGGGFGAAGGFGGRGG 94


>gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]
          Length = 217

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 40/58 (68%), Positives = 40/58 (68%), Gaps = 11/58 (18%)

Query: 7   PRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGG--GGGGGGGRGGG 62
           PRGGG GGRGG        GRGG G G GRGGGFRG GRGGGGGG  GG GGG RG G
Sbjct: 168 PRGGGRGGRGG--------GRGGGGRGGGRGGGFRG-GRGGGGGGFRGGRGGGFRGRG 216



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 48/122 (39%), Positives = 58/122 (47%), Gaps = 16/122 (13%)

Query: 13  GGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGR 72
           GGRGGF        RGG GGG  RGG      RGGGGGGGGG   G G GGF  GG RG 
Sbjct: 6   GGRGGFN-------RGGGGGGFNRGGS-SNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGG 57

Query: 73  GRGGKRGNQSGKNVMVEPHRH--EGVFICRGKEDALVTKNLVP--GESVYGEKRVSISEG 128
              G+      + V++    H  E   +C+   D    +N VP     VY E +  I + 
Sbjct: 58  FNKGQDQGPPERVVLLGEFLHPCEDDIVCKCTTD----ENKVPYFNAPVYLENKEQIGKV 113

Query: 129 DD 130
           D+
Sbjct: 114 DE 115



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 32/52 (61%), Positives = 32/52 (61%)

Query: 28  GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRG 79
           G  G  RG G G RG GRGGGG GGG GGG RGG G   GG RG   GG RG
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRG 214



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 31/45 (68%), Positives = 31/45 (68%), Gaps = 4/45 (8%)

Query: 4   GFSPRGGGFGGRGGFGDRGG--RGGRGGFGGG--RGRGGGFRGRG 44
           G   RGGG GG G  G RGG  RGGRGG GGG   GRGGGFRGRG
Sbjct: 172 GRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRGRG 216



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 34/58 (58%), Positives = 35/58 (60%), Gaps = 10/58 (17%)

Query: 8  RGGGFGG--RGGFG---DRGG-----RGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGG 55
          RGGG GG  RGG G   +RGG     RGG GG GGG  RGGG  G GRGGG GG   G
Sbjct: 4  RGGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNKG 61



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 30/50 (60%), Positives = 31/50 (62%), Gaps = 3/50 (6%)

Query: 35  GRGGGFRGRGRGGGGGG-GGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           G  G  RG GRGG GGG GGGG GG  GGGF   G RG G GG RG + G
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFR--GGRGGGGGGFRGGRGG 210



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 33/61 (54%), Positives = 36/61 (59%), Gaps = 13/61 (21%)

Query: 4  GFSPRGGGFGG--RGGFGD--RGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGR 59
          GF+ RGGG GG  RGG  +  RGG GG GG        G FRG GRGG G GGG GG  +
Sbjct: 10 GFN-RGGGGGGFNRGGSSNHFRGGGGGGGG--------GNFRGGGRGGFGRGGGRGGFNK 60

Query: 60 G 60
          G
Sbjct: 61 G 61



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 24/45 (53%), Positives = 25/45 (55%), Gaps = 3/45 (6%)

Query: 40  FRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGK-RGNQSG 83
           F  R  G  G   GGG GGRGGG    GG RG GRGG  RG + G
Sbjct: 157 FLPRPPGEKGPPRGGGRGGRGGG--RGGGGRGGGRGGGFRGGRGG 199


>gi|9506713 nucleolar protein family A, member 1 [Homo sapiens]
          Length = 217

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 40/58 (68%), Positives = 40/58 (68%), Gaps = 11/58 (18%)

Query: 7   PRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGG--GGGGGGGRGGG 62
           PRGGG GGRGG        GRGG G G GRGGGFRG GRGGGGGG  GG GGG RG G
Sbjct: 168 PRGGGRGGRGG--------GRGGGGRGGGRGGGFRG-GRGGGGGGFRGGRGGGFRGRG 216



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 48/122 (39%), Positives = 58/122 (47%), Gaps = 16/122 (13%)

Query: 13  GGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGR 72
           GGRGGF        RGG GGG  RGG      RGGGGGGGGG   G G GGF  GG RG 
Sbjct: 6   GGRGGFN-------RGGGGGGFNRGGS-SNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGG 57

Query: 73  GRGGKRGNQSGKNVMVEPHRH--EGVFICRGKEDALVTKNLVP--GESVYGEKRVSISEG 128
              G+      + V++    H  E   +C+   D    +N VP     VY E +  I + 
Sbjct: 58  FNKGQDQGPPERVVLLGEFLHPCEDDIVCKCTTD----ENKVPYFNAPVYLENKEQIGKV 113

Query: 129 DD 130
           D+
Sbjct: 114 DE 115



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 32/52 (61%), Positives = 32/52 (61%)

Query: 28  GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRG 79
           G  G  RG G G RG GRGGGG GGG GGG RGG G   GG RG   GG RG
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRG 214



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 31/45 (68%), Positives = 31/45 (68%), Gaps = 4/45 (8%)

Query: 4   GFSPRGGGFGGRGGFGDRGG--RGGRGGFGGG--RGRGGGFRGRG 44
           G   RGGG GG G  G RGG  RGGRGG GGG   GRGGGFRGRG
Sbjct: 172 GRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRGRG 216



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 34/58 (58%), Positives = 35/58 (60%), Gaps = 10/58 (17%)

Query: 8  RGGGFGG--RGGFG---DRGG-----RGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGG 55
          RGGG GG  RGG G   +RGG     RGG GG GGG  RGGG  G GRGGG GG   G
Sbjct: 4  RGGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNKG 61



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 30/50 (60%), Positives = 31/50 (62%), Gaps = 3/50 (6%)

Query: 35  GRGGGFRGRGRGGGGGG-GGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           G  G  RG GRGG GGG GGGG GG  GGGF   G RG G GG RG + G
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFR--GGRGGGGGGFRGGRGG 210



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 33/61 (54%), Positives = 36/61 (59%), Gaps = 13/61 (21%)

Query: 4  GFSPRGGGFGG--RGGFGD--RGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGR 59
          GF+ RGGG GG  RGG  +  RGG GG GG        G FRG GRGG G GGG GG  +
Sbjct: 10 GFN-RGGGGGGFNRGGSSNHFRGGGGGGGG--------GNFRGGGRGGFGRGGGRGGFNK 60

Query: 60 G 60
          G
Sbjct: 61 G 61



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 24/45 (53%), Positives = 25/45 (55%), Gaps = 3/45 (6%)

Query: 40  FRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGK-RGNQSG 83
           F  R  G  G   GGG GGRGGG    GG RG GRGG  RG + G
Sbjct: 157 FLPRPPGEKGPPRGGGRGGRGGG--RGGGGRGGGRGGGFRGGRGG 199


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 41/79 (51%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 9   GGGFGGRGGFGDRGGRGG--RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHS 66
           GG  GGRGG  DRGG GG  RGG GG RG   G RG  RGG GGG  GG GG  G     
Sbjct: 513 GGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ 572

Query: 67  GGNRGRGRGGKRGNQSGKN 85
            G R  GRGG      G++
Sbjct: 573 MGGRRGGRGGPGKMDKGEH 591



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 47/99 (47%), Positives = 51/99 (51%), Gaps = 5/99 (5%)

Query: 1   MKPGFSPRGGGFGGRGGFGDRGGRGG---RGGFGG-GRGRGGGFRGRGRGGGGGGGGGGG 56
           + P F P GG  G  G  G RGGRGG   RGG GG  RG  GG RG  RGG G   GG G
Sbjct: 496 LPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFG 555

Query: 57  GGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVE-PHRHE 94
           GGR GG     G      GG+RG + G   M +  HR E
Sbjct: 556 GGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQE 594



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/159 (27%), Positives = 61/159 (38%), Gaps = 12/159 (7%)

Query: 5   FSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGG---GFRGRGRGGGGGGGGGGGGGRGG 61
           +    GGF G G      G   RG   GG  RGG   G RG GRGG G  G  GG  + G
Sbjct: 222 YGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG 281

Query: 62  GGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICR----GKEDALVTKNLVPGE-- 115
           G    G +   G        S  + +     ++ V +       K+  +V  N   G+  
Sbjct: 282 GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPM 341

Query: 116 -SVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVD 153
             +Y +K     +GD  + Y   +P  +K A     G D
Sbjct: 342 IHIYLDKETGKPKGDATVSYE--DPPTAKAAVEWFDGKD 378



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 28/57 (49%), Positives = 28/57 (49%)

Query: 27  RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           RGG     GRG     RG  GG GG GG  G  GG G   GG   RG  G RGN SG
Sbjct: 399 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSG 455



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 33/79 (41%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 2   KPGFSPRGGGFGGRGGFGD----RGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGG 57
           KP  +   GG   R G G     RGG GG GG GG  GR GG       GG  GG    G
Sbjct: 392 KPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGG------RGGDRGGFPPRG 445

Query: 58  GRGGGGFHSGGNRGRGRGG 76
            RG  G  SGG   + R G
Sbjct: 446 PRGSRGNPSGGGNVQHRAG 464



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/77 (42%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 1   MKPGFSPRGG-GFGG--RGGFGDRGGRGGRGGFGGGRG-RGGGFRGRGRGGGGGGGGGGG 56
           M+ G  PR G G     RGG G  GG GG  G  GGRG   GGF  RG  G  G   GGG
Sbjct: 398 MRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGG 457

Query: 57  GGRGGGGFHSGGNRGRG 73
             +   G     N G G
Sbjct: 458 NVQHRAGDWQCPNPGCG 474



 Score = 32.7 bits (73), Expect = 0.44
 Identities = 17/34 (50%), Positives = 17/34 (50%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRG 37
           G   RGG  GGRGG G  G RGG    GG    G
Sbjct: 254 GGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEG 287



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 17/35 (48%), Positives = 17/35 (48%), Gaps = 2/35 (5%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGG 38
           GF   G   GGRG  G RGG G  G  GG    GG
Sbjct: 250 GFDRGGMSRGGRG--GGRGGMGSAGERGGFNKPGG 282


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 41/79 (51%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 9   GGGFGGRGGFGDRGGRGG--RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHS 66
           GG  GGRGG  DRGG GG  RGG GG RG   G RG  RGG GGG  GG GG  G     
Sbjct: 568 GGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ 627

Query: 67  GGNRGRGRGGKRGNQSGKN 85
            G R  GRGG      G++
Sbjct: 628 MGGRRGGRGGPGKMDKGEH 646



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 47/99 (47%), Positives = 51/99 (51%), Gaps = 5/99 (5%)

Query: 1   MKPGFSPRGGGFGGRGGFGDRGGRGG---RGGFGG-GRGRGGGFRGRGRGGGGGGGGGGG 56
           + P F P GG  G  G  G RGGRGG   RGG GG  RG  GG RG  RGG G   GG G
Sbjct: 551 LPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFG 610

Query: 57  GGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVE-PHRHE 94
           GGR GG     G      GG+RG + G   M +  HR E
Sbjct: 611 GGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQE 649



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 28/69 (40%), Positives = 29/69 (42%), Gaps = 4/69 (5%)

Query: 5   FSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGF 64
           +    GGF G G      G   RG   GG  RG    G  RGG GGG GG G G  GG  
Sbjct: 278 YGQESGGFSGPGENRSMSGPDNRGRGRGGFDRG----GMSRGGRGGGRGGMGAGERGGFN 333

Query: 65  HSGGNRGRG 73
             GG    G
Sbjct: 334 KPGGPMDEG 342



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 28/57 (49%), Positives = 28/57 (49%)

Query: 27  RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           RGG     GRG     RG  GG GG GG  G  GG G   GG   RG  G RGN SG
Sbjct: 454 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSG 510



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 33/79 (41%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 2   KPGFSPRGGGFGGRGGFGD----RGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGG 57
           KP  +   GG   R G G     RGG GG GG GG  GR GG       GG  GG    G
Sbjct: 447 KPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGG------RGGDRGGFPPRG 500

Query: 58  GRGGGGFHSGGNRGRGRGG 76
            RG  G  SGG   + R G
Sbjct: 501 PRGSRGNPSGGGNVQHRAG 519



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/77 (42%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 1   MKPGFSPRGG-GFGG--RGGFGDRGGRGGRGGFGGGRG-RGGGFRGRGRGGGGGGGGGGG 56
           M+ G  PR G G     RGG G  GG GG  G  GGRG   GGF  RG  G  G   GGG
Sbjct: 453 MRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGG 512

Query: 57  GGRGGGGFHSGGNRGRG 73
             +   G     N G G
Sbjct: 513 NVQHRAGDWQCPNPGCG 529



 Score = 36.2 bits (82), Expect = 0.040
 Identities = 22/49 (44%), Positives = 23/49 (46%), Gaps = 4/49 (8%)

Query: 38  GGFRGRGRGGGGGGGGGGGGGRGG---GGFHSGGNRGRGRGGKRGNQSG 83
           GGF G G      G    G GRGG   GG   GG RG GRGG    + G
Sbjct: 283 GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGG-RGGGRGGMGAGERG 330



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 21/47 (44%), Positives = 22/47 (46%), Gaps = 6/47 (12%)

Query: 39  GFRGRGRGGGGGGG------GGGGGGRGGGGFHSGGNRGRGRGGKRG 79
           G  G+  GG  G G      G    GRG GGF  GG    GRGG RG
Sbjct: 276 GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG 322


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 41/79 (51%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 9   GGGFGGRGGFGDRGGRGG--RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHS 66
           GG  GGRGG  DRGG GG  RGG GG RG   G RG  RGG GGG  GG GG  G     
Sbjct: 574 GGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ 633

Query: 67  GGNRGRGRGGKRGNQSGKN 85
            G R  GRGG      G++
Sbjct: 634 MGGRRGGRGGPGKMDKGEH 652



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 47/99 (47%), Positives = 51/99 (51%), Gaps = 5/99 (5%)

Query: 1   MKPGFSPRGGGFGGRGGFGDRGGRGG---RGGFGG-GRGRGGGFRGRGRGGGGGGGGGGG 56
           + P F P GG  G  G  G RGGRGG   RGG GG  RG  GG RG  RGG G   GG G
Sbjct: 557 LPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFG 616

Query: 57  GGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVE-PHRHE 94
           GGR GG     G      GG+RG + G   M +  HR E
Sbjct: 617 GGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQE 655



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 28/69 (40%), Positives = 29/69 (42%), Gaps = 4/69 (5%)

Query: 5   FSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGF 64
           +    GGF G G      G   RG   GG  RG    G  RGG GGG GG G G  GG  
Sbjct: 284 YGQESGGFSGPGENRSMSGPDNRGRGRGGFDRG----GMSRGGRGGGRGGMGAGERGGFN 339

Query: 65  HSGGNRGRG 73
             GG    G
Sbjct: 340 KPGGPMDEG 348



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 28/57 (49%), Positives = 28/57 (49%)

Query: 27  RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           RGG     GRG     RG  GG GG GG  G  GG G   GG   RG  G RGN SG
Sbjct: 460 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSG 516



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 33/79 (41%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 2   KPGFSPRGGGFGGRGGFGD----RGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGG 57
           KP  +   GG   R G G     RGG GG GG GG  GR GG       GG  GG    G
Sbjct: 453 KPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGG------RGGDRGGFPPRG 506

Query: 58  GRGGGGFHSGGNRGRGRGG 76
            RG  G  SGG   + R G
Sbjct: 507 PRGSRGNPSGGGNVQHRAG 525



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/77 (42%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 1   MKPGFSPRGG-GFGG--RGGFGDRGGRGGRGGFGGGRG-RGGGFRGRGRGGGGGGGGGGG 56
           M+ G  PR G G     RGG G  GG GG  G  GGRG   GGF  RG  G  G   GGG
Sbjct: 459 MRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGG 518

Query: 57  GGRGGGGFHSGGNRGRG 73
             +   G     N G G
Sbjct: 519 NVQHRAGDWQCPNPGCG 535



 Score = 36.2 bits (82), Expect = 0.040
 Identities = 22/49 (44%), Positives = 23/49 (46%), Gaps = 4/49 (8%)

Query: 38  GGFRGRGRGGGGGGGGGGGGGRGG---GGFHSGGNRGRGRGGKRGNQSG 83
           GGF G G      G    G GRGG   GG   GG RG GRGG    + G
Sbjct: 289 GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGG-RGGGRGGMGAGERG 336



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 21/47 (44%), Positives = 22/47 (46%), Gaps = 6/47 (12%)

Query: 39  GFRGRGRGGGGGGG------GGGGGGRGGGGFHSGGNRGRGRGGKRG 79
           G  G+  GG  G G      G    GRG GGF  GG    GRGG RG
Sbjct: 282 GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG 328


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
           sapiens]
          Length = 656

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 41/79 (51%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 9   GGGFGGRGGFGDRGGRGG--RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHS 66
           GG  GGRGG  DRGG GG  RGG GG RG   G RG  RGG GGG  GG GG  G     
Sbjct: 569 GGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ 628

Query: 67  GGNRGRGRGGKRGNQSGKN 85
            G R  GRGG      G++
Sbjct: 629 MGGRRGGRGGPGKMDKGEH 647



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 47/99 (47%), Positives = 51/99 (51%), Gaps = 5/99 (5%)

Query: 1   MKPGFSPRGGGFGGRGGFGDRGGRGG---RGGFGG-GRGRGGGFRGRGRGGGGGGGGGGG 56
           + P F P GG  G  G  G RGGRGG   RGG GG  RG  GG RG  RGG G   GG G
Sbjct: 552 LPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFG 611

Query: 57  GGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVE-PHRHE 94
           GGR GG     G      GG+RG + G   M +  HR E
Sbjct: 612 GGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQE 650



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/159 (27%), Positives = 61/159 (38%), Gaps = 12/159 (7%)

Query: 5   FSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGG---GFRGRGRGGGGGGGGGGGGGRGG 61
           +    GGF G G      G   RG   GG  RGG   G RG GRGG G  G  GG  + G
Sbjct: 278 YGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG 337

Query: 62  GGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICR----GKEDALVTKNLVPGE-- 115
           G    G +   G        S  + +     ++ V +       K+  +V  N   G+  
Sbjct: 338 GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPM 397

Query: 116 -SVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVD 153
             +Y +K     +GD  + Y   +P  +K A     G D
Sbjct: 398 IHIYLDKETGKPKGDATVSYE--DPPTAKAAVEWFDGKD 434



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 28/57 (49%), Positives = 28/57 (49%)

Query: 27  RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           RGG     GRG     RG  GG GG GG  G  GG G   GG   RG  G RGN SG
Sbjct: 455 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSG 511



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 33/79 (41%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 2   KPGFSPRGGGFGGRGGFGD----RGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGG 57
           KP  +   GG   R G G     RGG GG GG GG  GR GG       GG  GG    G
Sbjct: 448 KPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGG------RGGDRGGFPPRG 501

Query: 58  GRGGGGFHSGGNRGRGRGG 76
            RG  G  SGG   + R G
Sbjct: 502 PRGSRGNPSGGGNVQHRAG 520



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/77 (42%), Positives = 35/77 (45%), Gaps = 4/77 (5%)

Query: 1   MKPGFSPRGG-GFGG--RGGFGDRGGRGGRGGFGGGRG-RGGGFRGRGRGGGGGGGGGGG 56
           M+ G  PR G G     RGG G  GG GG  G  GGRG   GGF  RG  G  G   GGG
Sbjct: 454 MRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGG 513

Query: 57  GGRGGGGFHSGGNRGRG 73
             +   G     N G G
Sbjct: 514 NVQHRAGDWQCPNPGCG 530



 Score = 32.7 bits (73), Expect = 0.44
 Identities = 17/34 (50%), Positives = 17/34 (50%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRG 37
           G   RGG  GGRGG G  G RGG    GG    G
Sbjct: 310 GGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEG 343



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 17/35 (48%), Positives = 17/35 (48%), Gaps = 2/35 (5%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGG 38
           GF   G   GGRG  G RGG G  G  GG    GG
Sbjct: 306 GFDRGGMSRGGRG--GGRGGMGSAGERGGFNKPGG 338


>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
          Length = 518

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 44/96 (45%), Positives = 52/96 (54%), Gaps = 21/96 (21%)

Query: 8   RGGG--------FGGRGGFGDRGGRGGRGGFG-GGRGRGGGFRGRGRGGGGGGGGGGGGG 58
           RGGG        +GGRGG    GGRGGRGG+  GGRG G G + +G    GG GGGGG  
Sbjct: 336 RGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQ 395

Query: 59  RGG--------GGFH----SGGNRGRGRGGKRGNQS 82
            GG        GG+H    SGG +G G GG + + S
Sbjct: 396 DGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSS 431



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 35/82 (42%), Positives = 41/82 (50%), Gaps = 8/82 (9%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGG 63
           G   +GGG+     + D G  G RGG  GGRG      GRG  GG  G GGG GGRG   
Sbjct: 434 GSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRG------GRGGRGGRAGQGGGWGGRGSQN 487

Query: 64  FHSGG--NRGRGRGGKRGNQSG 83
           +H GG   +    GG + N SG
Sbjct: 488 YHQGGQFEQHFQHGGYQYNHSG 509



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 36/91 (39%), Positives = 44/91 (48%), Gaps = 10/91 (10%)

Query: 4   GFSPRG-------GGF--GGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGG 54
           GF P G       GG+  GG GGF       G G  GGG  +   ++  G  G  GGG G
Sbjct: 403 GFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRG 462

Query: 55  GGGGRGGGGFHSG-GNRGRGRGGKRGNQSGK 84
           G GGRGG G  +G G    GRG +  +Q G+
Sbjct: 463 GRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQ 493



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 39/88 (44%), Positives = 42/88 (47%), Gaps = 21/88 (23%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGG-GGGGGGGG-----------G 56
           GG  GGRGG+ +    GGRGG   G GRGG      RGG   GG GGG           G
Sbjct: 334 GGRGGGRGGY-EHSSYGGRGGHEQGGGRGG------RGGYDHGGRGGGRGNKHQGGWTDG 386

Query: 57  GGRGGGGFHSGGNRGRG--RGGKRGNQS 82
           G  GGGG+  GG R  G   GG  G  S
Sbjct: 387 GSGGGGGYQDGGYRDSGFQPGGYHGGHS 414



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 34/65 (52%), Positives = 36/65 (55%), Gaps = 4/65 (6%)

Query: 22  GGRGG-RGGFGGGR--GRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKR 78
           GGRGG RGG+      GRGG  +G GRGG GG   GG GG G G  H GG    G GG  
Sbjct: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGG-GRGNKHQGGWTDGGSGGGG 392

Query: 79  GNQSG 83
           G Q G
Sbjct: 393 GYQDG 397



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 31/66 (46%), Positives = 37/66 (56%), Gaps = 2/66 (3%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGG 68
           GG  G RGG   RGGRGGRGG GG  G+GGG+ GRG      GG      + GG  ++  
Sbjct: 451 GGHHGDRGG--GRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHS 508

Query: 69  NRGRGR 74
             G+GR
Sbjct: 509 GFGQGR 514



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 40/107 (37%), Positives = 47/107 (43%), Gaps = 22/107 (20%)

Query: 10  GGFGGRGGFGDRGGRGGR---GGFGGGRGRGGGFRGRGRGG--------GGGGGGGG--- 55
           GG GG GG+ D G R      GG+ GG    GG++G G GG        G G  GGG   
Sbjct: 386 GGSGGGGGYQDGGYRDSGFQPGGYHGGHS-SGGYQGGGYGGFQTSSSYTGSGYQGGGYQQ 444

Query: 56  ------GGGRGGGGFHSGGNRGR-GRGGKRGNQSGKNVMVEPHRHEG 95
                 GG  G  G   GG  GR GRGG+ G   G       + H+G
Sbjct: 445 DNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQG 491



 Score = 35.4 bits (80), Expect = 0.068
 Identities = 18/48 (37%), Positives = 23/48 (47%)

Query: 48  GGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEG 95
           GG GGG GG      G   G  +G GRGG+ G   G       ++H+G
Sbjct: 334 GGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQG 381


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 35/68 (51%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 26  GRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKN 85
           G GG G   G GG   G G GGG GGGGG GGG GGGG   GG  G G GG  G   G +
Sbjct: 130 GAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGG---GGGPGGGGGGPGGGLLGGS 186

Query: 86  VMVEPHRH 93
               PH H
Sbjct: 187 AHPHPHMH 194



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 33/57 (57%), Positives = 33/57 (57%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFH 65
           GG     GG G   G GG GG GGG G GGG  G G GG GGGGGG GGG  GG  H
Sbjct: 132 GGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAH 188



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 30/55 (54%), Positives = 30/55 (54%)

Query: 17  GFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRG 71
           G G  G   G GG   G G GGG  G G  GGG GGGGGGG  GGGG   GG  G
Sbjct: 130 GAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLG 184



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 36/66 (54%), Positives = 37/66 (56%), Gaps = 3/66 (4%)

Query: 6   SPRGGGFGGRGGFGDRGGRGG-RGGFGGGRGRGGGFRGRGRGGGGGGGGG-GGGGRGGGG 63
           SP      G GG G   G GG   G GGG G GGG  G G G GGGGGGG GGGG G GG
Sbjct: 122 SPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGG-GGPGGGPGGGGGGGPGGGGGGPGG 180

Query: 64  FHSGGN 69
              GG+
Sbjct: 181 GLLGGS 186



 Score = 36.2 bits (82), Expect = 0.040
 Identities = 19/35 (54%), Positives = 19/35 (54%)

Query: 3   PGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRG 37
           PG     GG GG GG    GG GG GG GGG G G
Sbjct: 147 PGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGG 181



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 17/31 (54%), Positives = 17/31 (54%), Gaps = 4/31 (12%)

Query: 3   PGFSPRGGGFGGRGGFGDRGGRGGRGGFGGG 33
           PG  P GGG GG GG    GG G  GG  GG
Sbjct: 159 PGGGPGGGGGGGPGG----GGGGPGGGLLGG 185


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 35/62 (56%), Positives = 38/62 (61%), Gaps = 2/62 (3%)

Query: 10  GGFGGRGGFGDRG-GRGGRGGFGGGRG-RGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSG 67
           GG GG G +G  G G G  GG+GGGR  RGGG RGR  GG G G GGGGG  GG G    
Sbjct: 498 GGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYGGSGRSGR 557

Query: 68  GN 69
           G+
Sbjct: 558 GS 559



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 31/61 (50%), Positives = 33/61 (54%)

Query: 13  GGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGR 72
           GG GG G  G  G  GG GGG G G  +RG G  G  GGG G G G GGG +   G  GR
Sbjct: 498 GGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYGGSGRSGR 557

Query: 73  G 73
           G
Sbjct: 558 G 558



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 31/64 (48%), Positives = 34/64 (53%), Gaps = 7/64 (10%)

Query: 22  GGRGGRGGFGG---GRGRGGGFRG----RGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGR 74
           GG GG G +G    G G GGG+ G    RG G  G  GGG G G GGGG   GG+   GR
Sbjct: 498 GGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYGGSGRSGR 557

Query: 75  GGKR 78
           G  R
Sbjct: 558 GSSR 561



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 31/61 (50%), Positives = 34/61 (55%), Gaps = 5/61 (8%)

Query: 28  GGFGGGRGRGGGFRGRGRGGGGGGG----GGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           GG GGG   G G  G G GGG GGG    GGG  GR GGG+ SG   G G  G  G +SG
Sbjct: 498 GGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYGGSG-RSG 556

Query: 84  K 84
           +
Sbjct: 557 R 557



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 34/82 (41%), Positives = 36/82 (43%), Gaps = 20/82 (24%)

Query: 4   GFSPRGGGFGGRGGFGDRGGR-----------------GGRGGFGGGRGRGGGFRGRGRG 46
           G+   G GFG R  +   G R                 GG GGFGGGRG G G  G    
Sbjct: 48  GYGIHGRGFGSRSLYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTG---A 104

Query: 47  GGGGGGGGGGGGRGGGGFHSGG 68
           GG GGGG GG G G   F  GG
Sbjct: 105 GGFGGGGFGGAGFGTSNFGLGG 126



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 33/73 (45%), Positives = 35/73 (47%), Gaps = 6/73 (8%)

Query: 9   GGGFGGRG-GFGDRG--GRGGRGGFG---GGRGRGGGFRGRGRGGGGGGGGGGGGGRGGG 62
           GGG+G  G GFG R     GG         GR   G  +G G GG GGG G G G  G G
Sbjct: 46  GGGYGIHGRGFGSRSLYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAG 105

Query: 63  GFHSGGNRGRGRG 75
           GF  GG  G G G
Sbjct: 106 GFGGGGFGGAGFG 118



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 30/62 (48%), Positives = 31/62 (50%), Gaps = 11/62 (17%)

Query: 4   GFSPRGGGFGGRGGFGDRGGR-----GGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGG 58
           G S   GG+GG  G G  GGR     G RG  GGG G G G      GGGG  GG G  G
Sbjct: 503 GGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCG------GGGGSYGGSGRSG 556

Query: 59  RG 60
           RG
Sbjct: 557 RG 558



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 28/55 (50%), Positives = 28/55 (50%), Gaps = 9/55 (16%)

Query: 4   GFSPRGG--GFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGG 56
           GF   GG  GFGG  GFG   G  G GGFGGG     GF G G G    G GG G
Sbjct: 81  GFCQGGGVGGFGGGRGFGV--GSTGAGGFGGG-----GFGGAGFGTSNFGLGGFG 128



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 34/82 (41%), Positives = 35/82 (42%), Gaps = 14/82 (17%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFG-GGRGRG-------GGFRG-----RGRGGGGGGGGGG 55
           GGG    G      GR G GG+G  GRG G       GG R       GR   G   GGG
Sbjct: 28  GGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSISINLMGRSTSGFCQGGG 87

Query: 56  GGGRGGG-GFHSGGNRGRGRGG 76
            GG GGG GF  G     G GG
Sbjct: 88  VGGFGGGRGFGVGSTGAGGFGG 109



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 26/72 (36%), Positives = 26/72 (36%), Gaps = 21/72 (29%)

Query: 28 GGFGGGRGRGGGFRGRGRGGGGGGGGGGGG--------------------GRGGGGFHSG 67
          G  GG    G     RGR GGGG G  G G                    GR   GF  G
Sbjct: 26 GSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSISINLMGRSTSGFCQG 85

Query: 68 GNRGRGRGGKRG 79
          G  G G GG RG
Sbjct: 86 GGVG-GFGGGRG 96


>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
           [Homo sapiens]
          Length = 320

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 39/82 (47%), Positives = 44/82 (53%), Gaps = 9/82 (10%)

Query: 8   RGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSG 67
           RGGGFGG   FG  G   GRGGFGG RG GGG+ G G G  G G  G   G GGG ++  
Sbjct: 206 RGGGFGGNDNFGRGGNFSGRGGFGGSRG-GGGYGGSGDGYNGFGNDGSNFG-GGGSYNDF 263

Query: 68  GNR-------GRGRGGKRGNQS 82
           GN        G  +GG  G +S
Sbjct: 264 GNYNNQSSNFGPMKGGNFGGRS 285



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 32/62 (51%), Positives = 34/62 (54%), Gaps = 1/62 (1%)

Query: 23  GRGGRGGFGGGRGRG-GGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQ 81
           GR G G FGGGRG G GG    GRGG   G GG GG RGGGG+   G+   G G    N 
Sbjct: 195 GRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNF 254

Query: 82  SG 83
            G
Sbjct: 255 GG 256



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 37/68 (54%), Positives = 39/68 (57%), Gaps = 8/68 (11%)

Query: 11  GFGGRGGFGDRGGRGGRGGFGGGR--GRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGG 68
           G  G G FG  GGRGG  GFGG    GRGG F GRG  G GG  GGGG G  G G++  G
Sbjct: 195 GRSGSGNFG--GGRGG--GFGGNDNFGRGGNFSGRG--GFGGSRGGGGYGGSGDGYNGFG 248

Query: 69  NRGRGRGG 76
           N G   GG
Sbjct: 249 NDGSNFGG 256



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 36/100 (36%), Positives = 42/100 (42%), Gaps = 26/100 (26%)

Query: 8   RGGGFGGRGGFG-DRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGG-------------- 52
           RGG F GRGGFG  RGG     G+GG      GF   G   GGGG               
Sbjct: 218 RGGNFSGRGGFGGSRGGG----GYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNF 273

Query: 53  ----GGGGGGRGGGGFHSGGN---RGRGRGGKRGNQSGKN 85
               GG  GGR  G +  GG    + R +GG  G+ S  +
Sbjct: 274 GPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSS 313



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 10/87 (11%)

Query: 4   GFSPRGGGFGGRG----GFGDRGGRGGRGG----FGGGRGRGGGFRGRGRGGGGGGGGGG 55
           G S  GGG+GG G    GFG+ G   G GG    FG    +   F G  +GG  GG   G
Sbjct: 229 GGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNF-GPMKGGNFGGRSSG 287

Query: 56  GGGRGGGGFHSGGNRGRGRGGKRGNQS 82
             G GG  F    N+G G GG   + S
Sbjct: 288 PYGGGGQYFAKPRNQG-GYGGSSSSSS 313



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 20/41 (48%), Positives = 22/41 (53%)

Query: 43  RGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
           RGR G G  GGG GGG GG      G    GRGG  G++ G
Sbjct: 194 RGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG 234


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 44/83 (53%), Positives = 45/83 (54%), Gaps = 13/83 (15%)

Query: 6   SPRGGGFGG-------RGGFGDRGGRGGR--GGFGGGRGRGGGFRGRGRGGGGGGGGGGG 56
           S R GGFGG        GG+G  GG GG   GGFGGGRG G GF G G  GG GG GG G
Sbjct: 75  SSRAGGFGGGRSSCGFAGGYG--GGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGPG 132

Query: 57  GGRGGGGFHSGGNRGRGRGGKRG 79
              G G F  GG  G G GG  G
Sbjct: 133 VFGGPGSF--GGPGGFGPGGFPG 153



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 35/61 (57%), Positives = 35/61 (57%), Gaps = 3/61 (4%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFG--GGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHS 66
           GGGFGG  G G  GGRG   GFG  GG G  GGF G G   GG G  GG GG G GGF  
Sbjct: 95  GGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGPG-VFGGPGSFGGPGGFGPGGFPG 153

Query: 67  G 67
           G
Sbjct: 154 G 154



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 37/87 (42%), Positives = 37/87 (42%), Gaps = 12/87 (13%)

Query: 4   GFSPRGGGFGGRG----------GFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGG 53
           GF    G FG R                 G    GGFGGGR   G   G G G GG  GG
Sbjct: 45  GFRSGAGSFGSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGG 104

Query: 54  GGGGGRG-GGGFHSGGNRGRGRGGKRG 79
           G GGGRG G GF   G  G G GG  G
Sbjct: 105 GFGGGRGVGSGFGGAGGFG-GAGGFGG 130



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 41/115 (35%), Positives = 41/115 (35%), Gaps = 37/115 (32%)

Query: 2   KPGFSPRGGGFGGR------------------GGFGDRGGRGGRGGFG------------ 31
           K  FS R  GF GR                   G G  G R G G FG            
Sbjct: 7   KKSFSGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKS 66

Query: 32  ------GGRGRGGGF-RGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRG 79
                  G  R GGF  GR   G  GG GGG GG  GGGF  G   G G GG  G
Sbjct: 67  ISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGG 121



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 25/58 (43%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 27  RGGFGGGRGRG-GGFRGRGRGGGGGGGG-GGGGGRGGGGFHSGGNRGRGRGGKRGNQS 82
           RG FGG  G G GG++G        G G  GG G G GG  SG   GRG  G   + S
Sbjct: 523 RGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSS 580



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 23/68 (33%), Positives = 26/68 (38%)

Query: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGG 68
           G   G  GG    G  G +GG       G G  G    G GG   G  GGRG  G +   
Sbjct: 520 GSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSS 579

Query: 69  NRGRGRGG 76
           + G   GG
Sbjct: 580 SSGSRLGG 587



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 29/75 (38%), Positives = 32/75 (42%), Gaps = 2/75 (2%)

Query: 10  GGFGGRGGFGDRGGRGG-RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGG 68
           G FGG  G G  G +GG       G G  GG  G G GG   G  GG G  G     S G
Sbjct: 524 GVFGGVSGSGSGGYKGGSSSSSSSGYGVSGG-SGSGYGGVSSGSTGGRGSSGSYQSSSSG 582

Query: 69  NRGRGRGGKRGNQSG 83
           +R  G G    + SG
Sbjct: 583 SRLGGAGSISVSHSG 597



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 33/87 (37%), Positives = 35/87 (40%), Gaps = 17/87 (19%)

Query: 8   RGGGFGGRGGFGDRGGRGGRGGFGG------GRGRGGGFRGRGRGGGGGGGGGGGGGRG- 60
           R GG GG    G  G R G G FG       G  +             GG GGG    G 
Sbjct: 35  RSGGAGG----GACGFRSGAGSFGSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGF 90

Query: 61  ----GGGFHSGGNRGRGRGGKRGNQSG 83
               GGGF  GG+ G G GG RG  SG
Sbjct: 91  AGGYGGGF--GGSYGGGFGGGRGVGSG 115



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 25/78 (32%), Positives = 30/78 (38%), Gaps = 1/78 (1%)

Query: 6   SPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFH 65
           S    G+G  GG G   G G   G  GGRG  G ++    G   GG G       G G  
Sbjct: 543 SSSSSGYGVSGGSGSGYG-GVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSS 601

Query: 66  SGGNRGRGRGGKRGNQSG 83
           SG  +  G  G +    G
Sbjct: 602 SGSIQTSGGSGYKSGGGG 619



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 25/71 (35%), Positives = 28/71 (39%), Gaps = 7/71 (9%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGG------GGGGGGGGGG 57
           G+   GG   G GG    G  GGRG  G  +    G R  G G       G G   G   
Sbjct: 548 GYGVSGGSGSGYGGVSS-GSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQ 606

Query: 58  GRGGGGFHSGG 68
             GG G+ SGG
Sbjct: 607 TSGGSGYKSGG 617


>gi|4502565 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 32/47 (68%), Positives = 32/47 (68%), Gaps = 2/47 (4%)

Query: 19 GDRGGRGGRGGFGGGRGR--GGGFRGRGRGGGGGGGGGGGGGRGGGG 63
          G  GG GG GG GGG G   GG   G G GGGGGGGGGGGGG GGGG
Sbjct: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 32/56 (57%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 24 RGGRGGFGGGRGRGGGFRGRGRG---GGGGGGGGGGGGRGGGGFHSGGNRGRGRGG 76
          +GG GG GGG G GGG      G   G GGGGGGGGGG GGGG   GG   R  GG
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 32/52 (61%), Positives = 33/52 (63%), Gaps = 5/52 (9%)

Query: 8  RGGGFGGRGGFGDRGGRGG-RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGG 58
          +GGG GG GG G  GG G   GG   G G GGG    G GGGGGGGGGGGGG
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGG----GGGGGGGGGGGGGGG 56



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 23/43 (53%), Positives = 24/43 (55%)

Query: 41 RGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
          +G G GGGGGGG GGG G   GG  SG   G G GG  G   G
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGG 51



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 24/48 (50%), Positives = 25/48 (52%), Gaps = 11/48 (22%)

Query: 43 RGRGGGGGGGGGGGGG-----------RGGGGFHSGGNRGRGRGGKRG 79
          +G GGGGGGGGG GGG            GGGG   GG  G G GG  G
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56


>gi|51599151 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 32/47 (68%), Positives = 32/47 (68%), Gaps = 2/47 (4%)

Query: 19 GDRGGRGGRGGFGGGRGR--GGGFRGRGRGGGGGGGGGGGGGRGGGG 63
          G  GG GG GG GGG G   GG   G G GGGGGGGGGGGGG GGGG
Sbjct: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 32/56 (57%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 24 RGGRGGFGGGRGRGGGFRGRGRG---GGGGGGGGGGGGRGGGGFHSGGNRGRGRGG 76
          +GG GG GGG G GGG      G   G GGGGGGGGGG GGGG   GG   R  GG
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 32/52 (61%), Positives = 33/52 (63%), Gaps = 5/52 (9%)

Query: 8  RGGGFGGRGGFGDRGGRGG-RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGG 58
          +GGG GG GG G  GG G   GG   G G GGG    G GGGGGGGGGGGGG
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGG----GGGGGGGGGGGGGGG 56



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 23/43 (53%), Positives = 24/43 (55%)

Query: 41 RGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
          +G G GGGGGGG GGG G   GG  SG   G G GG  G   G
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGG 51



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 24/48 (50%), Positives = 25/48 (52%), Gaps = 11/48 (22%)

Query: 43 RGRGGGGGGGGGGGGG-----------RGGGGFHSGGNRGRGRGGKRG 79
          +G GGGGGGGGG GGG            GGGG   GG  G G GG  G
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 37/80 (46%), Positives = 42/80 (52%), Gaps = 10/80 (12%)

Query: 7   PRGGGFGGRGGFGDRGGRGGRGGFGGGRGR---------GGGFRGRGRGGGGGGGG-GGG 56
           P+   + G GG G R  RGGRGG G G GR         GGG+   G  GGGGGGG    
Sbjct: 175 PKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAY 234

Query: 57  GGRGGGGFHSGGNRGRGRGG 76
           GG GGG  + G + G G GG
Sbjct: 235 GGGGGGSSYGGSDYGNGFGG 254



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 41/92 (44%), Positives = 44/92 (47%), Gaps = 19/92 (20%)

Query: 9   GGGFGGRGGFGDRGGRGGR---GGFGGGRGRGGGFRGRGRGGGG--------------GG 51
           GGG+   GG+G  GG GG    GG GGG   GG   G G GG G              GG
Sbjct: 214 GGGYNSYGGYGGGGG-GGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGG 272

Query: 52  GGGGGGGRGGGGFHSGGNR-GRGRGGKRGNQS 82
           GGGGGG   GG  +SG  R G G GG  G  S
Sbjct: 273 GGGGGGSSWGGRSNSGPYRGGYGGGGGYGGSS 304



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 41/100 (41%), Positives = 46/100 (46%), Gaps = 18/100 (18%)

Query: 10  GGFGGRGGFGDR-------GGRGGRGGFGG-GRGRGGGFRGRGRGGGGGGG-GGGGGGRG 60
           GG GGRG  G R       GG GG   +GG G G GGG+   G GGGGG   GG   G G
Sbjct: 193 GGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYG-GGGGGSSYGGSDYGNG 251

Query: 61  GGGFHS--------GGNRGRGRGGKRGNQSGKNVMVEPHR 92
            GGF S        G  +  G GG  G+  G      P+R
Sbjct: 252 FGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYR 291



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 29/73 (39%), Positives = 34/73 (46%), Gaps = 1/73 (1%)

Query: 4   GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGG 63
           G++  GGG GG   +G      G GGFG        +     GGGGGGGG   GGR   G
Sbjct: 230 GYNAYGGG-GGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSG 288

Query: 64  FHSGGNRGRGRGG 76
            + GG  G G  G
Sbjct: 289 PYRGGYGGGGGYG 301



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 17/38 (44%), Positives = 20/38 (52%)

Query: 5   FSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRG 42
           + P   G GG GG    GGR   G + GG G GGG+ G
Sbjct: 265 YGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGG 302


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.142    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,752,151
Number of Sequences: 37866
Number of extensions: 908645
Number of successful extensions: 42263
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 751
Number of HSP's successfully gapped in prelim test: 298
Number of HSP's that attempted gapping in prelim test: 10109
Number of HSP's gapped (non-prelim): 12960
length of query: 321
length of database: 18,247,518
effective HSP length: 102
effective length of query: 219
effective length of database: 14,385,186
effective search space: 3150355734
effective search space used: 3150355734
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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