Guide to the Human Genome
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Search of human proteins with 24497554

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24497554 homeobox A13 [Homo sapiens]
         (388 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24497554 homeobox A13 [Homo sapiens]                               790   0.0  
gi|24497536 homeobox C13 [Homo sapiens]                               280   1e-75
gi|116734702 homeobox D13 [Homo sapiens]                              272   4e-73
gi|62865866 homeobox B13 [Homo sapiens]                               251   6e-67
gi|23510368 homeobox D11 [Homo sapiens]                                96   5e-20
gi|194363768 homeobox D9 [Homo sapiens]                                89   9e-18
gi|194353946 homeobox D12 [Homo sapiens]                               86   7e-17
gi|7657166 homeobox C11 [Homo sapiens]                                 84   2e-16
gi|15029508 homeobox B9 [Homo sapiens]                                 84   2e-16
gi|5031759 homeobox A11 [Homo sapiens]                                 82   6e-16
gi|24497533 homeobox C10 [Homo sapiens]                                80   4e-15
gi|27804315 homeobox C12 [Homo sapiens]                                79   7e-15
gi|24497547 homeobox C9 [Homo sapiens]                                 79   9e-15
gi|18959212 GS homeobox 2 [Homo sapiens]                               77   2e-14
gi|24497526 homeobox B1 [Homo sapiens]                                 77   3e-14
gi|182765442 homeobox A10 isoform a [Homo sapiens]                     76   5e-14
gi|23510366 homeobox D10 [Homo sapiens]                                75   8e-14
gi|23097236 homeobox A9 [Homo sapiens]                                 75   1e-13
gi|126090909 engrailed homeobox 1 [Homo sapiens]                       74   2e-13
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]           74   2e-13
gi|24497551 homeobox A10 isoform b [Homo sapiens]                      74   3e-13
gi|24497538 homeobox C4 [Homo sapiens]                                 73   5e-13
gi|24497540 homeobox C4 [Homo sapiens]                                 73   5e-13
gi|33457326 GS homeobox 1 [Homo sapiens]                               72   8e-13
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    72   1e-12
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    72   1e-12
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    72   1e-12
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     71   2e-12
gi|169636435 caudal type homeobox 2 [Homo sapiens]                     70   4e-12
gi|4885127 caudal type homeobox 4 [Homo sapiens]                       70   4e-12

>gi|24497554 homeobox A13 [Homo sapiens]
          Length = 388

 Score =  790 bits (2039), Expect = 0.0
 Identities = 388/388 (100%), Positives = 388/388 (100%)

Query: 1   MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPH 60
           MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPH
Sbjct: 1   MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPH 60

Query: 61  PAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAA 120
           PAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAA
Sbjct: 61  PAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAA 120

Query: 121 AAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYP 180
           AAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYP
Sbjct: 121 AAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYP 180

Query: 181 CARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPY 240
           CARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPY
Sbjct: 181 CARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPY 240

Query: 241 HHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPH 300
           HHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPH
Sbjct: 241 HHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPH 300

Query: 301 LWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTN 360
           LWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTN
Sbjct: 301 LWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTN 360

Query: 361 LSERQVTIWFQNRRVKEKKVINKLKTTS 388
           LSERQVTIWFQNRRVKEKKVINKLKTTS
Sbjct: 361 LSERQVTIWFQNRRVKEKKVINKLKTTS 388


>gi|24497536 homeobox C13 [Homo sapiens]
          Length = 330

 Score =  280 bits (717), Expect = 1e-75
 Identities = 183/394 (46%), Positives = 223/394 (56%), Gaps = 80/394 (20%)

Query: 1   MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPH 60
           MT S+LLHPRW E ++M++Y++                   +AA +     G GGGG   
Sbjct: 1   MTTSLLLHPRWPE-SLMYVYED-------------------SAAESGIGGGGGGGGG--- 37

Query: 61  PAAAAAGGNFSVAAAAAA------AAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPP 114
                AGG  S A+   A       ++  A+ CR+L+ HP    P        AP  AP 
Sbjct: 38  -GTGGAGGGCSGASPGKAPSMDGLGSSCPASHCRDLLPHPVLGRP-------PAPLGAPQ 89

Query: 115 SAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGY- 173
            A                      P P      EAA+QC+P  A   SSS  A L YGY 
Sbjct: 90  GAVYTDI-----------------PAP------EAARQCAPPPAPPTSSS--ATLGYGYP 124

Query: 174 FGSGYYPCARMGPHPNAI-KSCAQPASAAAAAAFADKYMDTAGPA-AEEFSSRAKEFAFY 231
           FG  YY C R+  + N   K CA            DKY + +G    ++ SSRAKEFAFY
Sbjct: 125 FGGSYYGC-RLSHNVNLQQKPCAYHPG--------DKYPEPSGALPGDDLSSRAKEFAFY 175

Query: 232 HQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYC 291
              +A+     +Q MPGYLD+ VVPG+ G  E RH+ L +P+E YQ WAL NGW+ Q+YC
Sbjct: 176 -PSFASS----YQAMPGYLDVSVVPGISGHPEPRHDAL-IPVEGYQHWALSNGWDSQVYC 229

Query: 292 PKEQAQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDK 351
            KEQ+Q  HLWKS  PDVV    + SSYRRGRKKRVPYTKVQLKELE+EYA +KFITK+K
Sbjct: 230 SKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEK 289

Query: 352 RRRISATTNLSERQVTIWFQNRRVKEKKVINKLK 385
           RRRISATTNLSERQVTIWFQNRRVKEKKV++K K
Sbjct: 290 RRRISATTNLSERQVTIWFQNRRVKEKKVVSKSK 323


>gi|116734702 homeobox D13 [Homo sapiens]
          Length = 343

 Score =  272 bits (695), Expect = 4e-73
 Identities = 178/357 (49%), Positives = 217/357 (60%), Gaps = 51/357 (14%)

Query: 53  AGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEA 112
           A GGG        AGG  + +++++ AAAAA+ QCR  ++  AP+  G  S      G A
Sbjct: 14  ADGGG--------AGGAPASSSSSSVAAAAASGQCRGFLS--APVFAGTHS------GRA 57

Query: 113 PPSAAAAAAAAAAAAAAA---------AAASSSGGPGPAGPAGAEAAKQC---SPCSAAA 160
             +AAAAAAAAAAA+  A         +++SSS     A    A  AK+C   +P +AAA
Sbjct: 58  AAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAA 117

Query: 161 QSSSGPAALPYGY-FGSGYYPCAR---MGPHPNAIKSCAQPASAAAAAAFADKYMDTAGP 216
              S PA L YGY FG+GYY C     +G   NA+KS      A+      +KYMD +G 
Sbjct: 118 APPSAPA-LGYGYHFGNGYYSCRMSHGVGLQQNALKSSPH---ASLGGFPVEKYMDVSGL 173

Query: 217 A-----AEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGL 271
           A     A E  +RAKE +FY QGY + PY H   +PGY+DM       G GE RHE   +
Sbjct: 174 ASSSVPANEVPARAKEVSFY-QGYTS-PYQH---VPGYIDMV---STFGSGEPRHEAY-I 224

Query: 272 PMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLP-DVVSHPSDASSYRRGRKKRVPYT 330
            ME YQ W L NGWN Q+YC K+Q Q  H WKS+ P DV  +  D   YRRGRKKRVPYT
Sbjct: 225 SMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYT 284

Query: 331 KVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVINKLKTT 387
           K+QLKELE EYA NKFI KDKRRRISA TNLSERQVTIWFQNRRVK+KK+++KLK T
Sbjct: 285 KLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKKIVSKLKDT 341


>gi|62865866 homeobox B13 [Homo sapiens]
          Length = 284

 Score =  251 bits (642), Expect = 6e-67
 Identities = 138/246 (56%), Positives = 162/246 (65%), Gaps = 18/246 (7%)

Query: 144 PAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAA 203
           P  AE  KQC PC    Q +S PA +PYGYFG GYY C       +++K CAQ A+ AA 
Sbjct: 54  PGSAEPPKQCHPCPGVPQGTS-PAPVPYGYFGGGYYSCR---VSRSSLKPCAQAATLAA- 108

Query: 204 AAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGE 263
                 Y      A EE+ SR  EFAFY  GY  G Y   QPM  YLD+ VV  LG PGE
Sbjct: 109 ------YPAETPTAGEEYPSRPTEFAFY-PGYP-GTY---QPMASYLDVSVVQTLGAPGE 157

Query: 264 SRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVS-HPSDASSYRRG 322
            RH+ L LP++SYQ WAL  GWN QM C  EQ  P   WK+   D    HP DA ++RRG
Sbjct: 158 PRHDSL-LPVDSYQSWALAGGWNSQMCCQGEQNPPGPFWKAAFADSSGQHPPDACAFRRG 216

Query: 323 RKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVIN 382
           RKKR+PY+K QL+ELEREYA NKFITKDKRR+ISA T+LSERQ+TIWFQNRRVKEKKV+ 
Sbjct: 217 RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLA 276

Query: 383 KLKTTS 388
           K+K ++
Sbjct: 277 KVKNSA 282


>gi|23510368 homeobox D11 [Homo sapiens]
          Length = 338

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 97/286 (33%), Positives = 113/286 (39%), Gaps = 58/286 (20%)

Query: 100 GAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAA 159
           G       A G AP  AAAAAAAAAAAAA  AA      P PAG       K   P  AA
Sbjct: 92  GPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLP-PAGRRPDVLFKAPEPVCAA 150

Query: 160 AQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAE 219
                GPA    G   + Y    R G  P                 F   Y    GP   
Sbjct: 151 PGPPHGPA----GAASNFYSAVGRNGILPQG---------------FDQFYEAAPGPPF- 190

Query: 220 EFSSRAKEFAFYHQGYAAGPYHHHQPMP----GYLDM-PVVPGLGGPGESRHEPLGLPME 274
                            AGP     P P    G  D      G GG G S   P      
Sbjct: 191 -----------------AGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGS---PCTKATP 230

Query: 275 SYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQL 334
             +P     G  G    P  +A                 S A + +R RKKR PYTK Q+
Sbjct: 231 GSEPKGAAEGSGGDGEGPPGEAG------------AEKSSSAVAPQRSRKKRCPYTKYQI 278

Query: 335 KELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
           +ELERE+  N +I K+KR ++S   NL++RQV IWFQNRR+KEKK+
Sbjct: 279 RELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKL 324



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 51/167 (30%), Positives = 59/167 (35%), Gaps = 30/167 (17%)

Query: 37  GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAH--- 93
           G     +A   ++  G GGGG        AGG     AAAAAAAAAAA      M     
Sbjct: 77  GGGGGGSAGGGSSGGGPGGGG------GGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELL 130

Query: 94  -PAPLAPG----AASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSG-------GPGP 141
            PA   P     A     +APG  PP   A AA+   +A         G        PGP
Sbjct: 131 PPAGRRPDVLFKAPEPVCAAPG--PPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGP 188

Query: 142 --AGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGP 186
             AGP          P  AA +          G  G G  PC +  P
Sbjct: 189 PFAGPQPPPPPAPPQPEGAADKGDPRT-----GAGGGGGSPCTKATP 230



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 54/185 (29%), Positives = 60/185 (32%), Gaps = 42/185 (22%)

Query: 23  GGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAA--- 79
           GGG  A         AAAAAAAAAAA  A       P PA       F       AA   
Sbjct: 95  GGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLP-PAGRRPDVLFKAPEPVCAAPGP 153

Query: 80  ---AAAAANQCRNLMAHPAPLAPGAASAYSSAPG-----------EAPPSAAAAA----- 120
               A AA+   + +     L  G    Y +APG            APP    AA     
Sbjct: 154 PHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDP 213

Query: 121 --------------AAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGP 166
                         A   +    AA  S   G GP G AGAE +      SA A   S  
Sbjct: 214 RTGAGGGGGSPCTKATPGSEPKGAAEGSGGDGEGPPGEAGAEKSS-----SAVAPQRSRK 268

Query: 167 AALPY 171
              PY
Sbjct: 269 KRCPY 273


>gi|194363768 homeobox D9 [Homo sapiens]
          Length = 352

 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 96/340 (28%), Positives = 136/340 (40%), Gaps = 38/340 (11%)

Query: 48  AAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSS 107
           AA  G  G G     A  A G  + AA  A+ + A  +   +      P  P AA+A S 
Sbjct: 35  AARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSG 94

Query: 108 APGE-APPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGP 166
                 PP   AA+A+       +      G PG AG  G        P    +   SGP
Sbjct: 95  LYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGG--GPGRGPSPGPSGP 152

Query: 167 AALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAK 226
           A   +     G  P  R  P P    + A   S+++ +  +         A E   S   
Sbjct: 153 ANGRH----YGIKPETRAAPAP---ATAASTTSSSSTSLSSSSKRTECSVARESQGSSGP 205

Query: 227 EFAF--YHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGE----SRHEPLGLPMESYQPWA 280
           EF+   + Q  AA       P  G   +    G GG  E    S H   G  ++  +   
Sbjct: 206 EFSCNSFLQEKAAAATGGTGPGAG---IGAATGTGGSSEPSACSDHPIPGCSLKEEEK-- 260

Query: 281 LPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELERE 340
                  Q   P++Q   P+          +  ++    R  RKKR PYTK Q  ELE+E
Sbjct: 261 -------QHSQPQQQQLDPN----------NPAANWIHARSTRKKRCPYTKYQTLELEKE 303

Query: 341 YATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
           +  N ++T+D+R  ++   NL+ERQV IWFQNRR+K KK+
Sbjct: 304 FLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKM 343



 Score = 35.8 bits (81), Expect = 0.067
 Identities = 35/155 (22%), Positives = 54/155 (34%), Gaps = 5/155 (3%)

Query: 4   SVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAA 63
           S L HP ++ P  +    +  G       + + G    A         G G G  P P+ 
Sbjct: 93  SGLYHP-YVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSG 151

Query: 64  AAAGGNFSV---AAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAA 120
            A G ++ +     AA A A AA+    +  +  +       S    + G + P  +  +
Sbjct: 152 PANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNS 211

Query: 121 AAAAAAAAAAAAASSSGGPGPA-GPAGAEAAKQCS 154
                AAAA        G G A G  G+     CS
Sbjct: 212 FLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACS 246


>gi|194353946 homeobox D12 [Homo sapiens]
          Length = 270

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 61/204 (29%), Positives = 98/204 (48%), Gaps = 20/204 (9%)

Query: 195 AQPASAAAAAAFADKYMDTAGPAAEEFSSRA----KEFAFYHQGYAAGPYHHHQPMPGYL 250
           AQPA A A   F+  Y+  +GP   +  +      ++  FY    AAGP    +  P + 
Sbjct: 61  AQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFA 120

Query: 251 -DMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHL-------- 301
            +  + P +     ++++  G+   +     L  G         +   P +L        
Sbjct: 121 PESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAG 180

Query: 302 ----WKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISA 357
                + +LPD +      ++  R RKKR PYTK Q+ ELE E+  N+FI + KR+ +S 
Sbjct: 181 VASCLRPSLPDGLPW---GAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSN 237

Query: 358 TTNLSERQVTIWFQNRRVKEKKVI 381
             NLS++QV IWFQNRR+K+K+V+
Sbjct: 238 RLNLSDQQVKIWFQNRRMKKKRVV 261



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 52/170 (30%), Positives = 64/170 (37%), Gaps = 17/170 (10%)

Query: 19  LYDNGGGLVADELNKNMEGA---AAAAAAAAAAAAAGAGG-GGFPHPAAAAAGGNFSVAA 74
           L  NGG L A        GA   AA  A+ A A  AGA   GGF  P  A +G    +  
Sbjct: 29  LRPNGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSG---PLGL 85

Query: 75  AAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAAS 134
               A      Q +         AP AA+      G   PS A  ++ A A AA  AA  
Sbjct: 86  QPPTAKDGPEEQAKFY-------APEAAAGPEER-GRTRPSFAPESSLAPAVAALKAAKY 137

Query: 135 SSGGPGPAGPAGAEAAKQCSPCSAA-AQSSSGPAALPYGYFGSGYYPCAR 183
              G G A P G+    Q +PC+      + GP  L      +G   C R
Sbjct: 138 DYAGVGRATP-GSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLR 186


>gi|7657166 homeobox C11 [Homo sapiens]
          Length = 304

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 51/132 (38%), Positives = 70/132 (53%), Gaps = 7/132 (5%)

Query: 251 DMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVV 310
           D P  P   G GE++ EP   P       A       +    +E   P      +   V 
Sbjct: 164 DPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGA---EAEAEEENTNPSS--SGSAHSVA 218

Query: 311 SHPSD--ASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTI 368
             P+   A +  R RKKR PY+K Q++ELERE+  N +I K+KR ++S   NL++RQV I
Sbjct: 219 KEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKI 278

Query: 369 WFQNRRVKEKKV 380
           WFQNRR+KEKK+
Sbjct: 279 WFQNRRMKEKKL 290


>gi|15029508 homeobox B9 [Homo sapiens]
          Length = 250

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 70/229 (30%), Positives = 99/229 (43%), Gaps = 27/229 (11%)

Query: 170 PYGYFGSGYYPCARMGPHPNAIK--SCA-QPASAAAAAAFADKYMDTAG-------PAAE 219
           P   F SG Y  +R   H   ++  SC+ QP +    A++A      +G       P  +
Sbjct: 24  PPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASGSLPSVYHPYIQ 83

Query: 220 EFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPW 279
                  E  +        P     P  G   +   P LG PGE   +  G P  S +  
Sbjct: 84  PQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQ--GTPEYSLETS 141

Query: 280 A-----LPN---GWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTK 331
           A     L N   G+     C   + +         PD  +  ++    R  RKKR PYTK
Sbjct: 142 AGREAVLSNQRPGYGDNKICEGSEDKER-------PDQTNPSANWLHARSSRKKRCPYTK 194

Query: 332 VQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
            Q  ELE+E+  N ++T+D+R  ++   NLSERQV IWFQNRR+K KK+
Sbjct: 195 YQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKM 243


>gi|5031759 homeobox A11 [Homo sapiens]
          Length = 313

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 46/92 (50%), Positives = 63/92 (68%), Gaps = 6/92 (6%)

Query: 293 KEQAQPPHLWKSTLPDVVS-HPSD---ASSYRRGRKKRVPYTKVQLKELEREYATNKFIT 348
           KE+ + P    S+ P+  S H  D    SS +R RKKR PYTK Q++ELERE+  + +I 
Sbjct: 210 KERRRRPE--SSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYIN 267

Query: 349 KDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
           K+KR ++S   NL++RQV IWFQNRR+KEKK+
Sbjct: 268 KEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKI 299



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 1/128 (0%)

Query: 39  AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLA 98
           A +AA       A +    + HP  A +   +S          A           P  LA
Sbjct: 96  APSAAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLA 155

Query: 99  PGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSA 158
                   SA  + PP+A A +AAAAAAA  A A SSS   G  G     AA +      
Sbjct: 156 SSDYPGDKSAE-KGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRR 214

Query: 159 AAQSSSGP 166
             +SSS P
Sbjct: 215 RPESSSSP 222



 Score = 29.3 bits (64), Expect = 6.3
 Identities = 18/46 (39%), Positives = 23/46 (50%)

Query: 32  NKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAA 77
           +K+ E    AA A +AAAAA A G      + +  GG     AAAA
Sbjct: 162 DKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAA 207


>gi|24497533 homeobox C10 [Homo sapiens]
          Length = 342

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 73/247 (29%), Positives = 110/247 (44%), Gaps = 32/247 (12%)

Query: 144 PAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAA 203
           P   +    C   SA  ++ SGP A  Y +      P + +G H   + S  + + + +A
Sbjct: 102 PPSVKEENVCCMYSAEKRAKSGPEAALYSH----PLPESCLGEHEVPVPSYYRASPSYSA 157

Query: 204 AAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMP---GYLDMPVVPGLGG 260
               DK    +G  A +F       A + Q  +  P   H   P   G +  P  P    
Sbjct: 158 L---DKTPHCSG--ANDFE------APFEQRASLNPRAEHLESPQLGGKVSFPETPKSDS 206

Query: 261 PGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDASSY- 319
              S +E     +++ Q  A P G   +    KE+A+       T  +       A +  
Sbjct: 207 QTPSPNE-----IKTEQSLAGPKGSPSES--EKERAKAADSSPDTSDNEAKEEIKAENTT 259

Query: 320 ------RRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNR 373
                 + GRKKR PYTK Q  ELE+E+  N ++T+++R  IS T NL++RQV IWFQNR
Sbjct: 260 GNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNR 319

Query: 374 RVKEKKV 380
           R+K KK+
Sbjct: 320 RMKLKKM 326


>gi|27804315 homeobox C12 [Homo sapiens]
          Length = 282

 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 35/61 (57%), Positives = 49/61 (80%)

Query: 321 RGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
           R RKKR PY+K+QL ELE E+  N+FIT+ +RR +S   NLS++QV IWFQNRR+K+K++
Sbjct: 213 RSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRL 272

Query: 381 I 381
           +
Sbjct: 273 L 273


>gi|24497547 homeobox C9 [Homo sapiens]
          Length = 260

 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 53/132 (40%), Positives = 71/132 (53%), Gaps = 12/132 (9%)

Query: 260 GPGESRHEP---LGLPME--SYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPS 314
           GPGE R  P    G P E     P  LP+     +   K + +   L      D  +  +
Sbjct: 131 GPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADL------DPSNPVA 184

Query: 315 DASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRR 374
           +    R  RKKR PYTK Q  ELE+E+  N ++T+D+R  ++   NL+ERQV IWFQNRR
Sbjct: 185 NWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRR 244

Query: 375 VKEKKVINKLKT 386
           +K KK +NK KT
Sbjct: 245 MKMKK-MNKEKT 255


>gi|18959212 GS homeobox 2 [Homo sapiens]
          Length = 304

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 74/248 (29%), Positives = 103/248 (41%), Gaps = 35/248 (14%)

Query: 135 SSGGPG-PAGPAGAEAAKQCSPC-SAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIK 192
           S  GPG P+  +GA     C  C ++   SS G      G  G+G       G       
Sbjct: 44  SVSGPGCPSRKSGAFCV--CPLCVTSHLHSSRGSVGAGSGGAGAGVTGAGGSG------- 94

Query: 193 SCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPM-PGYLD 251
                 + AA A    K   ++ P   +F  R    A +H       +HHHQP  PG   
Sbjct: 95  -----VAGAAGALPLLKSQFSSAPGDAQFCPRVNH-AHHHHHPPQHHHHHHQPQQPG--- 145

Query: 252 MPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVS 311
                       +    LG P + + P      +N         A P      T+     
Sbjct: 146 SAAAAAAAAAAAAAAAALGHP-QHHAPVCTATTYN--------VADPRRFHCLTMGG--- 193

Query: 312 HPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQ 371
             SDAS    G++ R  +T  QL ELERE+++N ++++ +R  I+   NLSE+QV IWFQ
Sbjct: 194 --SDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQ 251

Query: 372 NRRVKEKK 379
           NRRVK KK
Sbjct: 252 NRRVKHKK 259



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 35/95 (36%), Positives = 44/95 (46%), Gaps = 6/95 (6%)

Query: 37  GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAP 96
           G+  A +  A A   GAGG G      A A G   +  +  ++A   A  C  +      
Sbjct: 74  GSVGAGSGGAGAGVTGAGGSG-----VAGAAGALPLLKSQFSSAPGDAQFCPRVNHAHHH 128

Query: 97  LAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAA 131
             P     +   P + P SAAAAAAAAAAAAAAAA
Sbjct: 129 HHPPQHHHHHHQP-QQPGSAAAAAAAAAAAAAAAA 162



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 20/37 (54%), Positives = 23/37 (62%)

Query: 37  GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVA 73
           G+AAAAAAAAAAAAA A  G   H A       ++VA
Sbjct: 145 GSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNVA 181



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 5/93 (5%)

Query: 117 AAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGS 176
           ++  +  A +  A A  + +GG G AG AGA    +    SA   +   P      +   
Sbjct: 71  SSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQFCPRV---NHAHH 127

Query: 177 GYYPCARMGPH--PNAIKSCAQPASAAAAAAFA 207
            ++P      H  P    S A  A+AAAAAA A
Sbjct: 128 HHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAA 160


>gi|24497526 homeobox B1 [Homo sapiens]
          Length = 301

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 89/302 (29%), Positives = 117/302 (38%), Gaps = 72/302 (23%)

Query: 96  PLAPGAASAYS--SAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAG-PAGAEAAKQ 152
           PL     SAYS  SAP   PPS+A A  + A+        SS      +G PA    +  
Sbjct: 13  PLCNRGPSAYSAHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQNSGYPAQQPPSTL 72

Query: 153 CSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGP-----HPNAIKSCAQPASAAAAAAFA 207
             P  ++A S   PAA    Y  S YYP  +        HP++          A     +
Sbjct: 73  GVPFPSSAPSGYAPAACSPSYGPSQYYPLGQSEGDGGYFHPSSY--------GAQLGGLS 124

Query: 208 DKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQP----------MPGYLDMPVVPG 257
           D Y   AG                  G   GPY    P           P Y D+     
Sbjct: 125 DGY--GAG------------------GAGPGPYPPQHPPYGNEQTASFAPAYADLL---- 160

Query: 258 LGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDAS 317
                E +  P   P E   P A    W       K +  PP   K + P + S PS   
Sbjct: 161 ----SEDKETPC--PSEPNTPTARTFDWM------KVKRNPPKTAKVSEPGLGS-PSGL- 206

Query: 318 SYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKE 377
                   R  +T  QL ELE+E+  NK++++ +R  I+AT  L+E QV IWFQNRR+K+
Sbjct: 207 --------RTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQ 258

Query: 378 KK 379
           KK
Sbjct: 259 KK 260


>gi|182765442 homeobox A10 isoform a [Homo sapiens]
          Length = 410

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 55/169 (32%), Positives = 81/169 (47%), Gaps = 29/169 (17%)

Query: 233 QGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCP 292
           Q   AGP+    P  G+ D+P     G    +R E     ++S  P  L  G  G     
Sbjct: 234 QQLGAGPFPAQPPGRGF-DLPPALASGSADAARKERA---LDSPPPPTLACGSGGGSQGD 289

Query: 293 KEQAQPPHLWKSTLPDVVSHPSDAS---------------------SYRRGRKKRVPYTK 331
           +E     H   S   ++   PS++S                     + + GRKKR PYTK
Sbjct: 290 EEA----HASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTK 345

Query: 332 VQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKV 380
            Q  ELE+E+  N ++T+++R  IS + +L++RQV IWFQNRR+K KK+
Sbjct: 346 HQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKM 394


>gi|23510366 homeobox D10 [Homo sapiens]
          Length = 340

 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 34/61 (55%), Positives = 47/61 (77%)

Query: 320 RRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
           + GRKKR PYTK Q  ELE+E+  N ++T+++R  IS + NL++RQV IWFQNRR+K KK
Sbjct: 264 KSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKK 323

Query: 380 V 380
           +
Sbjct: 324 M 324


>gi|23097236 homeobox A9 [Homo sapiens]
          Length = 272

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 34/61 (55%), Positives = 45/61 (73%)

Query: 320 RRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
           R  RKKR PYTK Q  ELE+E+  N ++T+D+R  ++   NL+ERQV IWFQNRR+K KK
Sbjct: 204 RSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 263

Query: 380 V 380
           +
Sbjct: 264 I 264


>gi|126090909 engrailed homeobox 1 [Homo sapiens]
          Length = 392

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 93/380 (24%), Positives = 139/380 (36%), Gaps = 73/380 (19%)

Query: 37  GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCR-------N 89
           GAAAAA     + +   G  G    + + + G+    +   A  +  A  C        +
Sbjct: 17  GAAAAATPGGLSLSLSPGASG---SSGSGSDGDSVPVSPQPAPPSPPAAPCLPPLAHHPH 73

Query: 90  LMAHPAPLAPG--AASAYSSAPG------------------------EAPPSAAAAAAAA 123
           L  HP P  P   AA A+   P                         + PP    AAAA 
Sbjct: 74  LPPHPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKEQPPPQLLVAAAAR 133

Query: 124 AAAAAAAAAASSSG----GPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYY 179
             A          G    G  P  P G  A    S   A   +   P        G+G  
Sbjct: 134 GGAGGGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPPDGSQPAAAGAG-- 191

Query: 180 PCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGP 239
             A    +P A  + A  A AAAAAA A K  DT G  +               G A  P
Sbjct: 192 --ASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGGGGSG--------------GGAGSP 235

Query: 240 YHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPP 299
                  P + +    P +   G +   P+ +  +S QP      W   +YC +   +P 
Sbjct: 236 GAQGTKYPEHGN----PAILLMGSANGGPV-VKTDSQQPLV----WPAWVYCTRYSDRP- 285

Query: 300 HLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATT 359
               S+ P         +  +  ++ R  +T  QL+ L+ E+  N++IT+ +R+ ++   
Sbjct: 286 ----SSGPRTRKLKKKKNE-KEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQEL 340

Query: 360 NLSERQVTIWFQNRRVKEKK 379
           +L+E Q+ IWFQN+R K KK
Sbjct: 341 SLNESQIKIWFQNKRAKIKK 360



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 42/130 (32%), Positives = 48/130 (36%), Gaps = 20/130 (15%)

Query: 23  GGGLVADELNKNMEGA---------AAAAAAAAAAAAAGAGGGGFPHPAAAAAG----GN 69
           GGG V  +  +   G          A  AA+   A  A  G      PAAA AG    GN
Sbjct: 138 GGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPPDGSQPAAAGAGASKAGN 197

Query: 70  FSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAA 129
            + AAAAAAAA AAA       A  A   P       S  G   P A           A 
Sbjct: 198 PAAAAAAAAAAVAAA-------AAAAAAKPSDTGGGGSGGGAGSPGAQGTKYPEHGNPAI 250

Query: 130 AAAASSSGGP 139
               S++GGP
Sbjct: 251 LLMGSANGGP 260



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 29/94 (30%), Positives = 38/94 (40%), Gaps = 6/94 (6%)

Query: 114 PSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAA--LPY 171
           P +   +A  AAAAA     S S  PG +G +G+ +     P S      S PAA  LP 
Sbjct: 8   PKSQRDSALGAAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPPAAPCLP- 66

Query: 172 GYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAA 205
                 ++P     P P   +  A PA     AA
Sbjct: 67  ---PLAHHPHLPPHPPPPPPQHLAAPAHQPQPAA 97


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 47/148 (31%), Positives = 71/148 (47%), Gaps = 18/148 (12%)

Query: 236 AAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQ 295
           A    HHH  +P  L +P            H P G   E  +P  L      Q+  P  +
Sbjct: 78  AVAHLHHH--LPAQLALP------------HPPAGPFPEGAEPGVLEEPNRVQLPFPWMK 123

Query: 296 AQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRI 355
           +   H WK       +  + A+     ++ R  YT+ QL ELE+E+  NK+I++ +R  +
Sbjct: 124 STKAHAWKGQW----AGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVEL 179

Query: 356 SATTNLSERQVTIWFQNRRVKEKKVINK 383
           +   NL+ER + IWFQNRR+K KK  +K
Sbjct: 180 AVMLNLTERHIKIWFQNRRMKWKKEEDK 207


>gi|24497551 homeobox A10 isoform b [Homo sapiens]
          Length = 94

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 33/61 (54%), Positives = 47/61 (77%)

Query: 320 RRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
           + GRKKR PYTK Q  ELE+E+  N ++T+++R  IS + +L++RQV IWFQNRR+K KK
Sbjct: 18  KSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKK 77

Query: 380 V 380
           +
Sbjct: 78  M 78


>gi|24497538 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 66/213 (30%), Positives = 89/213 (41%), Gaps = 54/213 (25%)

Query: 210 YMDTAGPAAEEFSSRA----KEFAFYHQGYAAGPYHHHQ-------PMPGYLDMPV-VPG 257
           Y+D   P  EE+S  +        +Y +   +G  HHHQ       P P Y +       
Sbjct: 12  YIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTS 71

Query: 258 LGGPGESR---------HEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPD 308
           L GPG SR         H P     E  Q    P   +G    P   +  P       PD
Sbjct: 72  LQGPGNSRGHGPAQAGHHHP-----EKSQSLCEPAPLSGASASP---SPAPPACSQPAPD 123

Query: 309 VVSHPSDASS--------------------YRRGRKKR--VPYTKVQLKELEREYATNKF 346
              HPS A+S                    Y  G  KR    YT+ Q+ ELE+E+  N++
Sbjct: 124 ---HPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY 180

Query: 347 ITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
           +T+ +R  I+ +  LSERQ+ IWFQNRR+K KK
Sbjct: 181 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213


>gi|24497540 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 66/213 (30%), Positives = 89/213 (41%), Gaps = 54/213 (25%)

Query: 210 YMDTAGPAAEEFSSRA----KEFAFYHQGYAAGPYHHHQ-------PMPGYLDMPV-VPG 257
           Y+D   P  EE+S  +        +Y +   +G  HHHQ       P P Y +       
Sbjct: 12  YIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTS 71

Query: 258 LGGPGESR---------HEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPD 308
           L GPG SR         H P     E  Q    P   +G    P   +  P       PD
Sbjct: 72  LQGPGNSRGHGPAQAGHHHP-----EKSQSLCEPAPLSGASASP---SPAPPACSQPAPD 123

Query: 309 VVSHPSDASS--------------------YRRGRKKR--VPYTKVQLKELEREYATNKF 346
              HPS A+S                    Y  G  KR    YT+ Q+ ELE+E+  N++
Sbjct: 124 ---HPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY 180

Query: 347 ITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379
           +T+ +R  I+ +  LSERQ+ IWFQNRR+K KK
Sbjct: 181 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213


>gi|33457326 GS homeobox 1 [Homo sapiens]
          Length = 264

 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 51/146 (34%), Positives = 76/146 (52%), Gaps = 18/146 (12%)

Query: 243 HQPMPGYLDMPVVPGLGGPGESR--HEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPH 300
           H P PG   +P++     P  S+  H PLG    +  P        G  + P   A    
Sbjct: 68  HGP-PGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSP--------GVAHGPAAAAAAAA 118

Query: 301 LWKST--LPD-----VVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRR 353
           L++++  LPD      +S  S ++     ++ R  +T  QL ELERE+A+N ++++ +R 
Sbjct: 119 LYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRI 178

Query: 354 RISATTNLSERQVTIWFQNRRVKEKK 379
            I+   NLSE+QV IWFQNRRVK KK
Sbjct: 179 EIATYLNLSEKQVKIWFQNRRVKHKK 204


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 60/168 (35%), Positives = 75/168 (44%), Gaps = 35/168 (20%)

Query: 37  GAAAAAAAAAAAAAAGAGGGGFPHPAAA------------------AAGGNFSVAAAAAA 78
           GA AAAAAAAAAAA G GGGG+   +A                     GG  S++ AAA 
Sbjct: 279 GAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338

Query: 79  AAA------AAANQ--------CRNLMAHPAPLAPGAASAYS--SAPGEAPPSAAAAAAA 122
           +AA      A  NQ           L+  P+P+      +Y   S+P   PP  +   + 
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 123 AAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALP 170
           AAAA AAA    ++ G G     GA+ A   SP  AAAQ  S PA  P
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYA-AASPAWAAAQQRSHPAMSP 445



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 58/210 (27%), Positives = 77/210 (36%), Gaps = 35/210 (16%)

Query: 13  EPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAG---------AGGGGFPHPA- 62
           +P V      GG     E N N  G+AA A+      A           + G G  H A 
Sbjct: 154 QPPVAVPGGGGGPAAVPEFN-NYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS 212

Query: 63  AAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAY------SSAPGEAPPSA 116
           AAAAG   S+     +      +QC +   +  P A G           S   G    + 
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272

Query: 117 AAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGS 176
           A  A A A AAAAAAAA+++GG G  G  G+ A       S+  Q   G           
Sbjct: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG--YGVLSSPRQQGGG----------- 319

Query: 177 GYYPCARMGPHPNAIKSCAQPASAAAAAAF 206
                  MGP      S ++ A+ +AA  F
Sbjct: 320 -----MMMGPGGGGAASLSKAAAGSAAGGF 344



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 78/301 (25%), Positives = 102/301 (33%), Gaps = 48/301 (15%)

Query: 22  NGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAA 81
           +GGG           GA A AAAAAAAAAA  GGGG          G +  ++A     +
Sbjct: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG----------GGYGGSSAGYGVLS 311

Query: 82  AAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSG---- 137
           +   Q   +M     + PG   A S +       AAA +AA      A      SG    
Sbjct: 312 SPRQQGGGMM-----MGPGGGGAASLS------KAAAGSAAGGFQRFAGQNQHPSGATPT 360

Query: 138 ------GPGPA----GPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPH 187
                  P P     G +  E +   +P    +Q  S  AA      G        +G  
Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420

Query: 188 PNAIKSCAQPASAAA-AAAFADKYMDTAGP--AAEEFSSRAKEFAFYHQGYAAGPYHHHQ 244
             A  + A PA AAA   +       T GP     + S          Q Y  G   H Q
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480

Query: 245 PMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKS 304
           P       P   G  GP   +  P+G+   +      P    G  Y P++Q      WK 
Sbjct: 481 PQQ---SSPYPGGSYGPPGPQRYPIGIQGRT------PGAMAGMQY-PQQQDSGDATWKE 530

Query: 305 T 305
           T
Sbjct: 531 T 531



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 38/129 (29%), Positives = 51/129 (39%), Gaps = 22/129 (17%)

Query: 52  GAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRN------------LMAHPAPLAP 99
           G  G G P P       N     AAAA   AAAN  ++            LMA  +P + 
Sbjct: 869 GGPGMGPPMPTV-----NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ 923

Query: 100 GAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGG----PGPAGPAGAEAAKQCSP 155
              ++ S    +APP + A A   ++AA+   A   S G    P P    G E      P
Sbjct: 924 PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTP-QP 982

Query: 156 CSAAAQSSS 164
            S + +SSS
Sbjct: 983 ESKSKKSSS 991



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 14/84 (16%)

Query: 39  AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLA 98
           AAAA   AAA +A +  G FP       G N S   A+++  +   N   +LM   AP  
Sbjct: 887 AAAAVMQAAANSAQSRQGSFP-------GMNQSGLMASSSPYSQPMNNSSSLMNTQAP-- 937

Query: 99  PGAASAYSSAPGEAPPSAAAAAAA 122
                 YS AP     SAA+   A
Sbjct: 938 -----PYSMAPAMVNSSAASVGLA 956


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 60/168 (35%), Positives = 75/168 (44%), Gaps = 35/168 (20%)

Query: 37  GAAAAAAAAAAAAAAGAGGGGFPHPAAA------------------AAGGNFSVAAAAAA 78
           GA AAAAAAAAAAA G GGGG+   +A                     GG  S++ AAA 
Sbjct: 279 GAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338

Query: 79  AAA------AAANQ--------CRNLMAHPAPLAPGAASAYS--SAPGEAPPSAAAAAAA 122
           +AA      A  NQ           L+  P+P+      +Y   S+P   PP  +   + 
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 123 AAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALP 170
           AAAA AAA    ++ G G     GA+ A   SP  AAAQ  S PA  P
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYA-AASPAWAAAQQRSHPAMSP 445



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 58/210 (27%), Positives = 77/210 (36%), Gaps = 35/210 (16%)

Query: 13  EPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAG---------AGGGGFPHPA- 62
           +P V      GG     E N N  G+AA A+      A           + G G  H A 
Sbjct: 154 QPPVAVPGGGGGPAAVPEFN-NYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS 212

Query: 63  AAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAY------SSAPGEAPPSA 116
           AAAAG   S+     +      +QC +   +  P A G           S   G    + 
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272

Query: 117 AAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGS 176
           A  A A A AAAAAAAA+++GG G  G  G+ A       S+  Q   G           
Sbjct: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG--YGVLSSPRQQGGG----------- 319

Query: 177 GYYPCARMGPHPNAIKSCAQPASAAAAAAF 206
                  MGP      S ++ A+ +AA  F
Sbjct: 320 -----MMMGPGGGGAASLSKAAAGSAAGGF 344



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 82/317 (25%), Positives = 107/317 (33%), Gaps = 63/317 (19%)

Query: 22  NGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAA 81
           +GGG           GA A AAAAAAAAAA  GGGG          G +  ++A     +
Sbjct: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG----------GGYGGSSAGYGVLS 311

Query: 82  AAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSG---- 137
           +   Q   +M     + PG   A S +       AAA +AA      A      SG    
Sbjct: 312 SPRQQGGGMM-----MGPGGGGAASLS------KAAAGSAAGGFQRFAGQNQHPSGATPT 360

Query: 138 ------GPGPA----GPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPH 187
                  P P     G +  E +   +P    +Q  S  AA      G        +G  
Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420

Query: 188 PNAIKSCAQPASAAA-AAAFADKYMDTAGP--AAEEFSSRAKEFAFYHQGYAAGPYHHHQ 244
             A  + A PA AAA   +       T GP     + S          Q Y  G   H Q
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480

Query: 245 PMPGYLDMPVVPGLGGPGESRHEPLGL-------------PMESYQPWALPNGWNGQMYC 291
           P       P   G  GP   +  P+G+             P +   P     G +G  YC
Sbjct: 481 PQQ---SSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSG--YC 535

Query: 292 PK-------EQAQPPHL 301
            +       +Q QPPHL
Sbjct: 536 QQGQQPYYSQQPQPPHL 552



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 47/170 (27%), Positives = 55/170 (32%), Gaps = 32/170 (18%)

Query: 48  AAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPA--PLAPGAASAY 105
           AAAAGA  GG    A    G +     AAA+ A AAA Q     +HPA  P  PG     
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ----RSHPAMSPGTPGPTMGR 454

Query: 106 SSAPGEAPPSAAAAAAAAAAAAAAAAAASSS----GGPGPAGP---------------AG 146
           S      P            +   +    SS    G  GP GP               AG
Sbjct: 455 SQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAG 514

Query: 147 AEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQ 196
            +  +Q  P     Q  S       GY   G  P     P P  +   AQ
Sbjct: 515 MQYPQQQMPPQYGQQGVS-------GYCQQGQQPYYSQQPQPPHLPPQAQ 557



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 45/188 (23%), Positives = 70/188 (37%), Gaps = 28/188 (14%)

Query: 52   GAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRN------------LMAHPAPLAP 99
            G  G G P P       N     AAAA   AAAN  ++            LMA  +P + 
Sbjct: 856  GGPGMGPPMPTV-----NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ 910

Query: 100  GAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAG-PAGAEAAKQCSPCSA 158
               ++ S    +APP + A A   ++AA+   A   S G      P  A+  ++ +P   
Sbjct: 911  PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPE 970

Query: 159  AAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAA 218
            +    S      Y   G    P     P P+ +     P+SA+ ++   D+    + P  
Sbjct: 971  SKSKDS------YSSQGISQPPTPGNLPVPSPM----SPSSASISSFHGDESDSISSPGW 1020

Query: 219  EEFSSRAK 226
             +  S  K
Sbjct: 1021 PKTPSSPK 1028



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 14/84 (16%)

Query: 39  AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLA 98
           AAAA   AAA +A +  G FP       G N S   A+++  +   N   +LM   AP  
Sbjct: 874 AAAAVMQAAANSAQSRQGSFP-------GMNQSGLMASSSPYSQPMNNSSSLMNTQAP-- 924

Query: 99  PGAASAYSSAPGEAPPSAAAAAAA 122
                 YS AP     SAA+   A
Sbjct: 925 -----PYSMAPAMVNSSAASVGLA 943


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 60/168 (35%), Positives = 75/168 (44%), Gaps = 35/168 (20%)

Query: 37  GAAAAAAAAAAAAAAGAGGGGFPHPAAA------------------AAGGNFSVAAAAAA 78
           GA AAAAAAAAAAA G GGGG+   +A                     GG  S++ AAA 
Sbjct: 279 GAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338

Query: 79  AAA------AAANQ--------CRNLMAHPAPLAPGAASAYS--SAPGEAPPSAAAAAAA 122
           +AA      A  NQ           L+  P+P+      +Y   S+P   PP  +   + 
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 123 AAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALP 170
           AAAA AAA    ++ G G     GA+ A   SP  AAAQ  S PA  P
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYA-AASPAWAAAQQRSHPAMSP 445



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 58/210 (27%), Positives = 77/210 (36%), Gaps = 35/210 (16%)

Query: 13  EPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAG---------AGGGGFPHPA- 62
           +P V      GG     E N N  G+AA A+      A           + G G  H A 
Sbjct: 154 QPPVAVPGGGGGPAAVPEFN-NYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSAS 212

Query: 63  AAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAY------SSAPGEAPPSA 116
           AAAAG   S+     +      +QC +   +  P A G           S   G    + 
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272

Query: 117 AAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGS 176
           A  A A A AAAAAAAA+++GG G  G  G+ A       S+  Q   G           
Sbjct: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG--YGVLSSPRQQGGG----------- 319

Query: 177 GYYPCARMGPHPNAIKSCAQPASAAAAAAF 206
                  MGP      S ++ A+ +AA  F
Sbjct: 320 -----MMMGPGGGGAASLSKAAAGSAAGGF 344



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 82/317 (25%), Positives = 107/317 (33%), Gaps = 63/317 (19%)

Query: 22  NGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAA 81
           +GGG           GA A AAAAAAAAAA  GGGG          G +  ++A     +
Sbjct: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG----------GGYGGSSAGYGVLS 311

Query: 82  AAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSG---- 137
           +   Q   +M     + PG   A S +       AAA +AA      A      SG    
Sbjct: 312 SPRQQGGGMM-----MGPGGGGAASLS------KAAAGSAAGGFQRFAGQNQHPSGATPT 360

Query: 138 ------GPGPA----GPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPH 187
                  P P     G +  E +   +P    +Q  S  AA      G        +G  
Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420

Query: 188 PNAIKSCAQPASAAA-AAAFADKYMDTAGP--AAEEFSSRAKEFAFYHQGYAAGPYHHHQ 244
             A  + A PA AAA   +       T GP     + S          Q Y  G   H Q
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480

Query: 245 PMPGYLDMPVVPGLGGPGESRHEPLGL-------------PMESYQPWALPNGWNGQMYC 291
           P       P   G  GP   +  P+G+             P +   P     G +G  YC
Sbjct: 481 PQQ---SSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSG--YC 535

Query: 292 PK-------EQAQPPHL 301
            +       +Q QPPHL
Sbjct: 536 QQGQQPYYSQQPQPPHL 552



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 47/170 (27%), Positives = 55/170 (32%), Gaps = 32/170 (18%)

Query: 48  AAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPA--PLAPGAASAY 105
           AAAAGA  GG    A    G +     AAA+ A AAA Q     +HPA  P  PG     
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ----RSHPAMSPGTPGPTMGR 454

Query: 106 SSAPGEAPPSAAAAAAAAAAAAAAAAAASSS----GGPGPAGP---------------AG 146
           S      P            +   +    SS    G  GP GP               AG
Sbjct: 455 SQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAG 514

Query: 147 AEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQ 196
            +  +Q  P     Q  S       GY   G  P     P P  +   AQ
Sbjct: 515 MQYPQQQMPPQYGQQGVS-------GYCQQGQQPYYSQQPQPPHLPPQAQ 557



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 38/129 (29%), Positives = 51/129 (39%), Gaps = 22/129 (17%)

Query: 52  GAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRN------------LMAHPAPLAP 99
           G  G G P P       N     AAAA   AAAN  ++            LMA  +P + 
Sbjct: 856 GGPGMGPPMPTV-----NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ 910

Query: 100 GAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGG----PGPAGPAGAEAAKQCSP 155
              ++ S    +APP + A A   ++AA+   A   S G    P P    G E      P
Sbjct: 911 PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTP-QP 969

Query: 156 CSAAAQSSS 164
            S + +SSS
Sbjct: 970 ESKSKKSSS 978



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 14/84 (16%)

Query: 39  AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLA 98
           AAAA   AAA +A +  G FP       G N S   A+++  +   N   +LM   AP  
Sbjct: 874 AAAAVMQAAANSAQSRQGSFP-------GMNQSGLMASSSPYSQPMNNSSSLMNTQAP-- 924

Query: 99  PGAASAYSSAPGEAPPSAAAAAAA 122
                 YS AP     SAA+   A
Sbjct: 925 -----PYSMAPAMVNSSAASVGLA 943


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 75/247 (30%), Positives = 94/247 (38%), Gaps = 48/247 (19%)

Query: 139 PGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPA 198
           PGPA PA      Q       A     P   P  Y     Y      P P        PA
Sbjct: 15  PGPARPASLGLGPQ-------AYGPPAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFPA 67

Query: 199 SAAA-AAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPG 257
                AAA+        GPAA   S  +  F                P P +  +P  PG
Sbjct: 68  PKDDWAAAYGP------GPAAPAASPASLAFG---------------PPPDFSPVPAPPG 106

Query: 258 LGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPSDAS 317
             GPG    +PLG P              G    P  Q   P+ W      V +     S
Sbjct: 107 -PGPGLLA-QPLGGP--------------GTPSSPGAQRPTPYEWMRR--SVAAGGGGGS 148

Query: 318 SYRRGRKK-RVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVK 376
              R + K RV YT  Q  ELE+E+  +++IT  ++  ++A   L+ERQV IWFQNRR K
Sbjct: 149 GKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAK 208

Query: 377 EKKVINK 383
           E+KV  K
Sbjct: 209 ERKVNKK 215



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 34/97 (35%), Positives = 40/97 (41%), Gaps = 12/97 (12%)

Query: 94  PAPLAPGAASAYSSA-PGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAA-- 150
           PAP      S+YS   P  APP+A  A   A     AAA      GPGPA PA + A+  
Sbjct: 37  PAPPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWAAAY-----GPGPAAPAASPASLA 91

Query: 151 ----KQCSPCSAAAQSSSGPAALPYGYFGSGYYPCAR 183
                  SP  A      G  A P G  G+   P A+
Sbjct: 92  FGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQ 128



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 29/85 (34%), Positives = 31/85 (36%), Gaps = 9/85 (10%)

Query: 94  PAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGP-----AGPAGAE 148
           PAP  P A  A    P  AP    AAA     AA AA+ AS + GP P       P G  
Sbjct: 53  PAPAPPTAWGA----PFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGPG 108

Query: 149 AAKQCSPCSAAAQSSSGPAALPYGY 173
                 P       SS  A  P  Y
Sbjct: 109 PGLLAQPLGGPGTPSSPGAQRPTPY 133



 Score = 29.3 bits (64), Expect = 6.3
 Identities = 29/95 (30%), Positives = 35/95 (36%), Gaps = 5/95 (5%)

Query: 47  AAAAAGAGGGGFPHPA---AAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAAS 103
           A A   A G  FP P    AAA G     AA AA+ A+ A     +    PAP  PG   
Sbjct: 54  APAPPTAWGAPFPAPKDDWAAAYGPG--PAAPAASPASLAFGPPPDFSPVPAPPGPGPGL 111

Query: 104 AYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGG 138
                 G   PS+  A           + A+  GG
Sbjct: 112 LAQPLGGPGTPSSPGAQRPTPYEWMRRSVAAGGGG 146


>gi|169636435 caudal type homeobox 2 [Homo sapiens]
          Length = 313

 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 81/268 (30%), Positives = 104/268 (38%), Gaps = 71/268 (26%)

Query: 124 AAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCAR 183
           AAAAAAAA   S+  PGP+ PA   A                    P     +GY P   
Sbjct: 46  AAAAAAAANLDSAQSPGPSWPAAYGA--------------------PLREDWNGYAP--- 82

Query: 184 MGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHH- 242
                          +AAAA A A      +  AA  +SS A     +H      P+HH 
Sbjct: 83  -------------GGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHH------PHHHP 123

Query: 243 HQPMPGY-----LDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQ 297
           H P         L   + PG  GP  +         E   P          M  P +Q+ 
Sbjct: 124 HHPAAAPSCASGLLQTLNPGPPGPAATA------AAEQLSPGGQRRNLCEWMRKPAQQSL 177

Query: 298 PPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISA 357
              +                  R   K RV YT  Q  ELE+E+  +++IT  ++  ++A
Sbjct: 178 GSQV----------------KTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAA 221

Query: 358 TTNLSERQVTIWFQNRRVKEKKVINKLK 385
           T  LSERQV IWFQNRR KE+K INK K
Sbjct: 222 TLGLSERQVKIWFQNRRAKERK-INKKK 248



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 44/120 (36%), Positives = 57/120 (47%), Gaps = 10/120 (8%)

Query: 39  AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPL- 97
           AAAAAAAA   +A + G  +P    A    +++  A   AAAAA      N +AH     
Sbjct: 46  AAAAAAAANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAA------NAVAHGLNGG 99

Query: 98  APGAASAYSSAPGEAPPSAAAAAAA--AAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSP 155
           +P AA  YSS P +  P           AAA + A+    +  PGP GPA   AA+Q SP
Sbjct: 100 SPAAAMGYSS-PADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSP 158


>gi|4885127 caudal type homeobox 4 [Homo sapiens]
          Length = 284

 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 67/249 (26%), Positives = 92/249 (36%), Gaps = 34/249 (13%)

Query: 135 SSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSC 194
           S GG G AG  G        P S  A   + PA   Y     GY     M PH  ++   
Sbjct: 20  SPGGDGTAGTGGTGGGGSPMPASNFA---AAPAFSHY----MGYPHMPSMDPHWPSLGVW 72

Query: 195 AQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPV 254
             P S        + +    GP++   +    +       + +  Y +  P+ G      
Sbjct: 73  GSPYSPPR-----EDWSVYPGPSSTMGTVPVNDVTSSPAAFCSTDYSNLGPVGGGTSGSS 127

Query: 255 VPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHLWKSTLPDVVSHPS 314
           +PG  G G       G    S                P      P+ W      V     
Sbjct: 128 LPGQAG-GSLVPTDAGAAKAS---------------SPSRSRHSPYAWMRKTVQVTGKT- 170

Query: 315 DASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRR 374
                R   K RV YT  Q  ELE+E+  N++IT  ++  ++    LSERQV IWFQNRR
Sbjct: 171 -----RTKEKYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRR 225

Query: 375 VKEKKVINK 383
            KE+K+I K
Sbjct: 226 AKERKMIKK 234



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 38/141 (26%), Positives = 49/141 (34%), Gaps = 29/141 (20%)

Query: 37  GAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAP 96
           G   +      A   G GGGG P PA+     NF  AAA A +         ++  H   
Sbjct: 16  GTLMSPGGDGTAGTGGTGGGGSPMPAS-----NF--AAAPAFSHYMGYPHMPSMDPHWPS 68

Query: 97  LA----------------PGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGG-- 138
           L                 PG +S   + P     S+ AA  +   +        +SG   
Sbjct: 69  LGVWGSPYSPPREDWSVYPGPSSTMGTVPVNDVTSSPAAFCSTDYSNLGPVGGGTSGSSL 128

Query: 139 PGPAG----PAGAEAAKQCSP 155
           PG AG    P  A AAK  SP
Sbjct: 129 PGQAGGSLVPTDAGAAKASSP 149


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.126    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,045,352
Number of Sequences: 37866
Number of extensions: 1060580
Number of successful extensions: 36553
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1026
Number of HSP's successfully gapped in prelim test: 939
Number of HSP's that attempted gapping in prelim test: 11482
Number of HSP's gapped (non-prelim): 12073
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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