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Search of human proteins with 24432009
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo
sapiens]
(854 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo ... 1719 0.0
gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo ... 579 e-165
gi|46195794 poly (ADP-ribose) polymerase family, member 16 [Homo... 53 1e-06
gi|110825963 poly (ADP-ribose) polymerase family, member 2 isofo... 41 0.005
gi|110825961 poly (ADP-ribose) polymerase family, member 2 isofo... 41 0.005
gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo... 36 0.13
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 32 1.9
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 32 1.9
gi|164419758 bromodomain containing 2 [Homo sapiens] 32 2.5
gi|4826806 bromodomain containing 2 [Homo sapiens] 32 2.5
gi|4506449 RNA binding motif, single stranded interacting protei... 32 2.5
gi|122937514 unc-13 homolog C [Homo sapiens] 32 3.3
gi|4759258 zinc finger, BED-type containing 1 [Homo sapiens] 32 3.3
gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens] 31 4.3
gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo ... 31 5.6
gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo ... 31 5.6
gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 31 5.6
gi|166235167 zinc finger protein ZNF-U69274 [Homo sapiens] 31 5.6
gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens] 30 7.3
gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens] 30 7.3
gi|110611170 ADAM metallopeptidase with thrombospondin type 1 mo... 30 7.3
gi|217416354 sphingosine kinase type 1-interacting protein isofo... 30 7.3
gi|217416352 sphingosine kinase type 1-interacting protein isofo... 30 7.3
gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens] 30 7.3
gi|50962882 G patch domain containing 8 [Homo sapiens] 30 7.3
gi|55741655 anoctamin 8 [Homo sapiens] 30 9.5
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 30 9.5
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 30 9.5
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 30 9.5
gi|109637791 transcription factor-like nuclear regulator [Homo s... 30 9.5
>gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo
sapiens]
Length = 854
Score = 1719 bits (4453), Expect = 0.0
Identities = 854/854 (100%), Positives = 854/854 (100%)
Query: 1 MGMCSRQERIQKDIDVVIQKSRAEKDCLFADFRYSDSTFTFTYVGGPRSVSYSVHVSEDY 60
MGMCSRQERIQKDIDVVIQKSRAEKDCLFADFRYSDSTFTFTYVGGPRSVSYSVHVSEDY
Sbjct: 1 MGMCSRQERIQKDIDVVIQKSRAEKDCLFADFRYSDSTFTFTYVGGPRSVSYSVHVSEDY 60
Query: 61 PDNTYVSSSENDEDVLVTTEPIPVIFHRIATELRKTNDINCCLSIKSKLQKENGEESRQN 120
PDNTYVSSSENDEDVLVTTEPIPVIFHRIATELRKTNDINCCLSIKSKLQKENGEESRQN
Sbjct: 61 PDNTYVSSSENDEDVLVTTEPIPVIFHRIATELRKTNDINCCLSIKSKLQKENGEESRQN 120
Query: 121 STVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVREIYGPHAVSLREYGAIDD 180
STVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVREIYGPHAVSLREYGAIDD
Sbjct: 121 STVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVREIYGPHAVSLREYGAIDD 180
Query: 181 VDIDLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQYLNGPVPTVDVFQISTKERFGL 240
VDIDLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQYLNGPVPTVDVFQISTKERFGL
Sbjct: 181 VDIDLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQYLNGPVPTVDVFQISTKERFGL 240
Query: 241 GHQLKKIMQTFVTQQWKQSKEKSNCLHNKKLSEKKVKSPLHLFSTLRRSPSYPPPGCGKS 300
GHQLKKIMQTFVTQQWKQSKEKSNCLHNKKLSEKKVKSPLHLFSTLRRSPSYPPPGCGKS
Sbjct: 241 GHQLKKIMQTFVTQQWKQSKEKSNCLHNKKLSEKKVKSPLHLFSTLRRSPSYPPPGCGKS 300
Query: 301 KSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVTKSHRTFGRSLSSDPRAEQAMTAIKSH 360
KSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVTKSHRTFGRSLSSDPRAEQAMTAIKSH
Sbjct: 301 KSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVTKSHRTFGRSLSSDPRAEQAMTAIKSH 360
Query: 361 KLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEHNTNLKPHKLLSRSYSSNLRMEEL 420
KLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEHNTNLKPHKLLSRSYSSNLRMEEL
Sbjct: 361 KLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEHNTNLKPHKLLSRSYSSNLRMEEL 420
Query: 421 YGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTSGLIGILTPSSSSSSQLAPNGA 480
YGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTSGLIGILTPSSSSSSQLAPNGA
Sbjct: 421 YGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTSGLIGILTPSSSSSSQLAPNGA 480
Query: 481 KCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQT 540
KCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQT
Sbjct: 481 KCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQT 540
Query: 541 LGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKK 600
LGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKK
Sbjct: 541 LGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKK 600
Query: 601 NYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQ 660
NYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQ
Sbjct: 601 NYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQ 660
Query: 661 LKFMHTPHQFLLLSSPPAKESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRL 720
LKFMHTPHQFLLLSSPPAKESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRL
Sbjct: 661 LKFMHTPHQFLLLSSPPAKESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRL 720
Query: 721 QLHGAMYGSGIYLSPMSSISFGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKKGQQSQFL 780
QLHGAMYGSGIYLSPMSSISFGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKKGQQSQFL
Sbjct: 721 QLHGAMYGSGIYLSPMSSISFGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKKGQQSQFL 780
Query: 781 QSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDANINTQEGGIH 840
QSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDANINTQEGGIH
Sbjct: 781 QSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDANINTQEGGIH 840
Query: 841 KEILRVIGNQTATG 854
KEILRVIGNQTATG
Sbjct: 841 KEILRVIGNQTATG 854
>gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo
sapiens]
Length = 630
Score = 579 bits (1492), Expect = e-165
Identities = 298/432 (68%), Positives = 343/432 (79%), Gaps = 6/432 (1%)
Query: 423 LKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTSGLIGILTPSSSSSSQLAPNGAKC 482
L+ +L+++S S K+ K E+F P + L L +G+ P + +S L K
Sbjct: 203 LRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGL-LCPQHVGL--PPPARTSPLVSGHCKN 259
Query: 483 IPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQTLG 542
IP + GFLVQ +++AEQRIP LNEYCVVCDE HVFQNG ML+P VC RELCVF+F TLG
Sbjct: 260 IPTLEYGFLVQIMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLG 319
Query: 543 VMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNY 602
VM+ AA+E+ATGA+VVDLLV+MCR+ALESPRK +IFEPYPSVVDP DP+ LAFNP+KKNY
Sbjct: 320 VMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPSVVDPTDPKTLAFNPKKKNY 379
Query: 603 DRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQLK 662
+R+ KALDS+ SIREMTQ YLEIKKQMDK DPLAHPLLQW+ISSNRSHIVKLP++R LK
Sbjct: 380 ERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSR-LK 438
Query: 663 FMHTPHQFLLLSSPPAKESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRLQL 722
FMHT HQFLLLSSPPAKE+ FR AKKL+GSTFAFHGSHIENWHSILRNGLV AS T+LQL
Sbjct: 439 FMHTSHQFLLLSSPPAKEARFRTAKKLYGSTFAFHGSHIENWHSILRNGLVNASYTKLQL 498
Query: 723 HGAMYGSGIYLSPMSSISFGYSGMNKKQ-KVSAKDEPASSSKSSNTSQSQKKGQQSQFLQ 781
HGA YG GIYLSP+SSISFGYSGM K Q ++ +KDE NT Q + QS+FLQ
Sbjct: 499 HGAAYGKGIYLSPISSISFGYSGMGKGQHRMPSKDELVQRYNRMNTI-PQTRSIQSRFLQ 557
Query: 782 SRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDANINTQEGGIHK 841
SRNL CIALCEVITS DL KHG IWV P +DHVCTRFFFVYEDGQVGDANINTQ+ I K
Sbjct: 558 SRNLNCIALCEVITSKDLQKHGNIWVCPVSDHVCTRFFFVYEDGQVGDANINTQDPKIQK 617
Query: 842 EILRVIGNQTAT 853
EI+RVIG Q T
Sbjct: 618 EIMRVIGTQVYT 629
Score = 202 bits (514), Expect = 1e-51
Identities = 105/216 (48%), Positives = 148/216 (68%), Gaps = 11/216 (5%)
Query: 124 EEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVREIYGPHAVSLREYGAIDDVDI 183
++DSEGDN+SEEF YG Q + +L++HPQL+AD+ AV+EIY ++VS+REYG IDDVDI
Sbjct: 10 DDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDI 69
Query: 184 DLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQYLNGPVPTVDVFQISTKERFGLGHQ 243
DLHI++SFLDEE++ AW+V+RTEPI++RL SL+QYL+GP P+++VFQ S KE FGLG Q
Sbjct: 70 DLHINISFLDEEVSTAWKVLRTEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQ 129
Query: 244 LKKIMQTFVTQQWKQ--------SKEKSNCLHNKKLSEKKVKSPLHLFSTLRRSPSYPPP 295
LKKI+ F +QQWK +EK + + KK ++ L +FS + +SPS+P
Sbjct: 130 LKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPIPKSPSFPII 189
Query: 296 GCGKSKSKLKSEQDGISKTHKLLRRTCSSTVKTDDV 331
K KL + + +L+ R+ S T+K V
Sbjct: 190 QDSMLKGKLGVPE---LRVGRLMNRSISCTMKNPKV 222
>gi|46195794 poly (ADP-ribose) polymerase family, member 16 [Homo
sapiens]
Length = 323
Score = 53.1 bits (126), Expect = 1e-06
Identities = 65/266 (24%), Positives = 105/266 (39%), Gaps = 62/266 (23%)
Query: 547 AADEIATGAQVV--DLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNYDR 604
AA A G ++ DL S+ SAL+S ++ + P+P+ D K+++
Sbjct: 7 AAAREAAGRDMLAADLRCSLFASALQSYKRDSVLRPFPASYARGDC---------KDFEA 57
Query: 605 VMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIV---KLPVNRQL 661
++ + +++E+ Q+ K+ D L+ W++SS I K +
Sbjct: 58 LLADASKLPNLKELLQSSGDNHKRAWD--------LVSWILSSKVLTIHSAGKAEFEKIQ 109
Query: 662 KFMHTPHQ--------FLLLSSPPAKESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLV 713
K PH F + PA + F K +AFHGS +EN+HSI+ NGL
Sbjct: 110 KLTGAPHTPVPAPDFLFEIEYFDPAN-AKFYETKGERDLIYAFHGSRLENFHSIIHNGLH 168
Query: 714 VASNTRLQLHGAMYGSGIYLSPMSSISFGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKK 773
N +++G G YL+ S++ YS
Sbjct: 169 CHLNKT-----SLFGEGTYLTSDLSLALIYS-------------------------PHGH 198
Query: 774 GQQSQFLQSRNLKCIALCEVITSSDL 799
G Q L L C+A+CEVI D+
Sbjct: 199 GWQHSLL-GPILSCVAVCEVIDHPDV 223
>gi|110825963 poly (ADP-ribose) polymerase family, member 2 isoform
2 [Homo sapiens]
Length = 570
Score = 40.8 bits (94), Expect = 0.005
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 696 FHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFGY 743
+HGS + NW IL +GL +A + G M+G GIY + MSS S Y
Sbjct: 414 WHGSRMSNWVGILSHGLRIAP-PEAPITGYMFGKGIYFADMSSKSANY 460
>gi|110825961 poly (ADP-ribose) polymerase family, member 2 isoform
1 [Homo sapiens]
Length = 583
Score = 40.8 bits (94), Expect = 0.005
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 696 FHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFGY 743
+HGS + NW IL +GL +A + G M+G GIY + MSS S Y
Sbjct: 427 WHGSRMSNWVGILSHGLRIAP-PEAPITGYMFGKGIYFADMSSKSANY 473
>gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo
sapiens]
Length = 1014
Score = 36.2 bits (82), Expect = 0.13
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 683 FRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFG 742
++ K+L +HGS N+ IL GL +A + G M+G GIY + M S S
Sbjct: 848 YKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAP-PEAPVTGYMFGKGIYFADMVSKSAN 906
Query: 743 Y 743
Y
Sbjct: 907 Y 907
>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
b [Homo sapiens]
Length = 533
Score = 32.3 bits (72), Expect = 1.9
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 679 KESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSS 738
+E F+A KL +HG+++ +IL +GL + ++ G G GIY + +S
Sbjct: 366 EEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHS-----GGRVGKGIYFASENS 420
Query: 739 ISFGY 743
S GY
Sbjct: 421 KSAGY 425
>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
a [Homo sapiens]
Length = 540
Score = 32.3 bits (72), Expect = 1.9
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 679 KESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSS 738
+E F+A KL +HG+++ +IL +GL + ++ G G GIY + +S
Sbjct: 373 EEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHS-----GGRVGKGIYFASENS 427
Query: 739 ISFGY 743
S GY
Sbjct: 428 KSAGY 432
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 32.0 bits (71), Expect = 2.5
Identities = 17/58 (29%), Positives = 29/58 (50%)
Query: 106 KSKLQKENGEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVRE 163
KS + + E S ++S+ EE+ E + D EE + + H+ +L+ L AV E
Sbjct: 475 KSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHE 532
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 32.0 bits (71), Expect = 2.5
Identities = 17/58 (29%), Positives = 29/58 (50%)
Query: 106 KSKLQKENGEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVRE 163
KS + + E S ++S+ EE+ E + D EE + + H+ +L+ L AV E
Sbjct: 475 KSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHE 532
>gi|4506449 RNA binding motif, single stranded interacting protein 2
[Homo sapiens]
Length = 407
Score = 32.0 bits (71), Expect = 2.5
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 740 SFGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKKGQQSQFLQSRNLKCIALCEVITSSDL 799
+FGY+ NKK VS + A S S++T S + L NL L T DL
Sbjct: 13 TFGYNRNNKKPYVSLAQQMAPPSPSNSTPNSSSGSNGNDQLSKTNLYIRGLQPGTTDQDL 72
Query: 800 HK----HGEI----WVVPNTDHVCTRFFFV 821
K +G+I ++ T + C + FV
Sbjct: 73 VKLCQPYGKIVSTKAILDKTTNKCKGYGFV 102
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 31.6 bits (70), Expect = 3.3
Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 12/128 (9%)
Query: 51 SYSVHVSEDYPDNTYVSSSENDEDVLVTTEPIPVIFHRIATELRKTNDINCCLSIKSKLQ 110
SY V ++ N V++S+N ED+L I + ELR + + N S +
Sbjct: 93 SYRVAIANGLQKNAKVTNSDN-EDLLQELSSIESSYSESLNELRSSTE-NQAQSTHTMPV 150
Query: 111 KENGEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQ------LEADLSAVREI 164
+ N R++S+ SEG +D E +G ++ +L K + +++LS +++
Sbjct: 151 RRN----RKSSSSLAPSEGSSDGERTLHGLKLGALRKLRKWKKSQECVSSDSELSTMKKS 206
Query: 165 YGPHAVSL 172
+G + SL
Sbjct: 207 WGIRSKSL 214
>gi|4759258 zinc finger, BED-type containing 1 [Homo sapiens]
Length = 694
Score = 31.6 bits (70), Expect = 3.3
Identities = 38/193 (19%), Positives = 74/193 (38%), Gaps = 29/193 (15%)
Query: 291 SYPPPGCGKSKSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVTKSHRTFGRSLSSDPRA 350
++P C KS + ++ + L+ S D + V H D +
Sbjct: 70 NHPEEFCEFVKSNTEQMREAFATAFSKLKPESSQQPGQDALAVKAGH-------GYDSKK 122
Query: 351 EQAMTAIKSHKLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEHNTNLKPHKLLSRS 410
+Q +TA + PA++ E + ++L ++ DPR E L SR
Sbjct: 123 QQELTAAVLGLICEGLYPASIVDEP-----TFKVLLKTA--DPRYE---------LPSRK 166
Query: 411 YSSNLRMEELYGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTSGLIGILTPSSS 470
Y S + E YG +L + + T++++ N ++L + +G+ P+
Sbjct: 167 YISTKAIPEKYGAVREVILKELAEATWCGISTDMWRSENQNRAYVTLAAHFLGLGAPNCL 226
Query: 471 SSSQLAPNGAKCI 483
S G++C+
Sbjct: 227 SM------GSRCL 233
>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
Length = 234
Score = 31.2 bits (69), Expect = 4.3
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Query: 109 LQKENGEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGE 147
++ E GEE + E+ S GD + EE Y G+V DGE
Sbjct: 182 VEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEV--DGE 218
>gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 30.8 bits (68), Expect = 5.6
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 341 GRSLSSDPRAEQAMTAIKSHKLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEHNTN 400
GRS+ DP T K+ KL P +E +K+ RL + G CE
Sbjct: 1234 GRSIRKDPFFRNLSTKSKNRKLPEPP----DNEDEDEDVKAERLKVKELMGCQCCEE--- 1286
Query: 401 LKPHKLLSRSYSS-NLRMEELYGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTS 459
KP ++S + + + + L K K+ +K S K + PN G+ ++ +
Sbjct: 1287 -KPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKS-TIIN 1344
Query: 460 GLIGILTPSS 469
L+G + P+S
Sbjct: 1345 ILVGDIEPTS 1354
>gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 30.8 bits (68), Expect = 5.6
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 341 GRSLSSDPRAEQAMTAIKSHKLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEHNTN 400
GRS+ DP T K+ KL P +E +K+ RL + G CE
Sbjct: 1234 GRSIRKDPFFRNLSTKSKNRKLPEPP----DNEDEDEDVKAERLKVKELMGCQCCEE--- 1286
Query: 401 LKPHKLLSRSYSS-NLRMEELYGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTS 459
KP ++S + + + + L K K+ +K S K + PN G+ ++ +
Sbjct: 1287 -KPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKS-TIIN 1344
Query: 460 GLIGILTPSS 469
L+G + P+S
Sbjct: 1345 ILVGDIEPTS 1354
>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
[Homo sapiens]
Length = 1005
Score = 30.8 bits (68), Expect = 5.6
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 5/90 (5%)
Query: 287 RRSPSYPPPGCGKSKSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVTKSHRTFGRSLSS 346
R SP PP SK K + GI K LRR+ S+T DD+ + R G ++
Sbjct: 563 RNSPFQIPPPSPDSKKKSR----GIMKLFGKLRRSQSTTFNPDDMSEPEFKRG-GTRATA 617
Query: 347 DPRAEQAMTAIKSHKLLNRPCPAAVKSEEC 376
PR + +S+ L+ P K + C
Sbjct: 618 GPRLGWSRDLGQSNSDLDMPFAKWTKEQVC 647
>gi|166235167 zinc finger protein ZNF-U69274 [Homo sapiens]
Length = 1053
Score = 30.8 bits (68), Expect = 5.6
Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 5/98 (5%)
Query: 732 YLSPMSSISFGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKKGQQSQFLQSRNLKCIALC 791
Y P+ F YS + + + A SS SSN++ ++ G S+ +++ ++C
Sbjct: 597 YKCPLCKKQFQYSASLRAHLIRHTRKDAPSSSSSNSTSNEASGTSSEKGRTKREFICSIC 656
Query: 792 ----EVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDG 825
+ S +H V P+ VC + F+Y+ G
Sbjct: 657 GRTLPKLYSLRIHMLKHTGVKPHACQVCGK-TFIYKHG 693
>gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]
Length = 111
Score = 30.4 bits (67), Expect = 7.3
Identities = 14/37 (37%), Positives = 19/37 (51%)
Query: 111 KENGEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGE 147
+ENGE+ N EE+ EG + EE G DG+
Sbjct: 42 EENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGD 78
>gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]
Length = 110
Score = 30.4 bits (67), Expect = 7.3
Identities = 14/37 (37%), Positives = 19/37 (51%)
Query: 111 KENGEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGE 147
+ENGE+ N EE+ EG + EE G DG+
Sbjct: 41 EENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGD 77
>gi|110611170 ADAM metallopeptidase with thrombospondin type 1
motif, 17 preproprotein [Homo sapiens]
Length = 1095
Score = 30.4 bits (67), Expect = 7.3
Identities = 14/32 (43%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
Query: 392 DPRCEHNTNLKPHKLLSRSYSSNLRMEELYGL 423
DPR +H L PHKL YS+N + + L+G+
Sbjct: 452 DPRSQHTVRL-PHKLPGMHYSANEQCQILFGM 482
>gi|217416354 sphingosine kinase type 1-interacting protein isoform 1
[Homo sapiens]
Length = 1700
Score = 30.4 bits (67), Expect = 7.3
Identities = 43/176 (24%), Positives = 76/176 (43%), Gaps = 11/176 (6%)
Query: 342 RSLSSDPRAEQAMTAIKSHKLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEH---N 398
RSL ++ + TA++ HK R K++E LK +L+ R E +
Sbjct: 977 RSLKRKKESQGSGTAVRKHKP-PRLSEIKRKTDEHPELKE-KLMNRVVDESMNLEDVPDS 1034
Query: 399 TNLKPHKLLSR-----SYSSNLRMEELYGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGR 453
NL +++ ++ +S M + G ++LLS S K+S E E ++E R
Sbjct: 1035 VNLFANEVAAKIMNLTEFSMVDGMWQAQGYPRNRLLSGDRWSRLKASSCESIPEEDSEAR 1094
Query: 454 RLSLTSGLIGILT-PSSSSSSQLAPNGAKCIPVRDRGFLVQTIEFAEQRIPVLNEY 508
+ GL+ L+ P S +SS + + I F+V +E + +L +Y
Sbjct: 1095 AYVNSLGLMSTLSQPVSRASSVSKQSSCESITDEFSRFMVNQMENEGRGFELLLDY 1150
>gi|217416352 sphingosine kinase type 1-interacting protein isoform 2
[Homo sapiens]
Length = 1671
Score = 30.4 bits (67), Expect = 7.3
Identities = 43/176 (24%), Positives = 76/176 (43%), Gaps = 11/176 (6%)
Query: 342 RSLSSDPRAEQAMTAIKSHKLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEH---N 398
RSL ++ + TA++ HK R K++E LK +L+ R E +
Sbjct: 977 RSLKRKKESQGSGTAVRKHKP-PRLSEIKRKTDEHPELKE-KLMNRVVDESMNLEDVPDS 1034
Query: 399 TNLKPHKLLSR-----SYSSNLRMEELYGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGR 453
NL +++ ++ +S M + G ++LLS S K+S E E ++E R
Sbjct: 1035 VNLFANEVAAKIMNLTEFSMVDGMWQAQGYPRNRLLSGDRWSRLKASSCESIPEEDSEAR 1094
Query: 454 RLSLTSGLIGILT-PSSSSSSQLAPNGAKCIPVRDRGFLVQTIEFAEQRIPVLNEY 508
+ GL+ L+ P S +SS + + I F+V +E + +L +Y
Sbjct: 1095 AYVNSLGLMSTLSQPVSRASSVSKQSSCESITDEFSRFMVNQMENEGRGFELLLDY 1150
>gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens]
Length = 548
Score = 30.4 bits (67), Expect = 7.3
Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 12/83 (14%)
Query: 223 PVPTVDVFQISTKERFGL--GHQLKKIMQTFVTQQWK----QSKEKSNCLHNKKLSEKKV 276
P PT+ V ER+ + QLK I + + +Q K + KE + L +K E+
Sbjct: 40 PFPTIYVDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAK 99
Query: 277 KSPLHLFSTLRRSPSYPPPGCGK 299
K T++ PS P P C K
Sbjct: 100 KI------TIKNDPSLPEPKCVK 116
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 30.4 bits (67), Expect = 7.3
Identities = 51/226 (22%), Positives = 82/226 (36%), Gaps = 24/226 (10%)
Query: 233 STKERFGLGHQLKKIMQTFVTQQWKQ----------SKEKSNCLHNKKLSEKKVKSPLHL 282
S KER G H+ KK + + + K+ SK +S K+ K+ K+
Sbjct: 664 SKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSA 723
Query: 283 FSTLRRSPSYPPPGCGK---SKSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVTKSHRT 339
+ R P PPG G + + +++ D S+ L SS K + + S
Sbjct: 724 PADSERGPKPEPPGSGSPAPPRRRRRAQDD--SQRRSLPAEEGSSGKKDEGGGGSSSQDH 781
Query: 340 FGRSLSSD--PRAEQAMTAIKSHKLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEH 397
GR + P + Q K + + E+ SHRL +S S E
Sbjct: 782 GGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEE 841
Query: 398 NTNLKPHKLLSRSYSSNLRMEELYGLKNHKLLSKSYSSAPKSSKTE 443
+ SRS S +H+ +SYSS+ +S +
Sbjct: 842 EEDSGSEHSRSRSRSGRRH-------SSHRSSRRSYSSSSDASSDQ 880
>gi|55741655 anoctamin 8 [Homo sapiens]
Length = 1232
Score = 30.0 bits (66), Expect = 9.5
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Query: 114 GEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVREIYGPHAVSLR 173
G+E ++ EED E + D EE GG ++ L K A+ A R GP +L
Sbjct: 580 GKEEDEDDEEEEDEEEEEDEEEGEEGGLLDCGLRLKK--VSFAERGAGRRRPGPSPEALL 637
Query: 174 EYGAIDDVDIDLHIDVSFLDEE 195
E G+ V+ L V L EE
Sbjct: 638 EEGSPTMVEKGLEPGVFTLAEE 659
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 30.0 bits (66), Expect = 9.5
Identities = 43/164 (26%), Positives = 71/164 (43%), Gaps = 32/164 (19%)
Query: 48 RSVSYSVHVSEDYPDNTYVSS-SENDED-------VLVTTEPIPVIFHRI---------A 90
+S Y+V VSED P T +++ S NDED V +P+P RI
Sbjct: 790 QSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQF--RIDPDSGTMYTM 847
Query: 91 TELRKTNDINCCLSIKSKLQKENGEESRQNSTVEE--DSEGDNDSEEF---YYGGQVNYD 145
EL N + L+I + ++NG + ++T E + ++++ +F +Y G + D
Sbjct: 848 MELDYENQVAYTLTI---MAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFED 904
Query: 146 GELHKHPQLE-ADLSAVREIYGPHAVSLREYGAIDDVDIDLHID 188
P +SA GP+ L + DD D D +I+
Sbjct: 905 AP----PSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIE 944
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 30.0 bits (66), Expect = 9.5
Identities = 15/51 (29%), Positives = 26/51 (50%)
Query: 457 LTSGLIGILTPSSSSSSQLAPNGAKCIPVRDRGFLVQTIEFAEQRIPVLNE 507
L G + I++P SS+S L P A+C+ L ++ E +Q + L +
Sbjct: 1304 LLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRK 1354
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo
sapiens]
Length = 1157
Score = 30.0 bits (66), Expect = 9.5
Identities = 36/150 (24%), Positives = 62/150 (41%), Gaps = 21/150 (14%)
Query: 232 ISTKERFGLGHQLKKIMQTFVTQQWKQSKEKSNCLHNKKLSEKKV-KSPLHLFSTLRRSP 290
+S KE+ L + KK++Q + Q+ K+S+ +KLSE + ++ + LF T +
Sbjct: 64 LSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEML---QKLSEVQASEAEMRLFYTTSKL- 119
Query: 291 SYPPPGCGKSKSKLKSEQD-----------GISKTHKLLRRTCSSTVKTDDVCVTKSHRT 339
G G K + D +S H+ RR S+ + ++ ++S
Sbjct: 120 -----GTGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELE 174
Query: 340 FGRSLSSDPRAEQAMTAIKSHKLLNRPCPA 369
L DP AE A + + P PA
Sbjct: 175 EESELDEDPAAEPAEAGVGTTVAPLPPAPA 204
>gi|109637791 transcription factor-like nuclear regulator [Homo
sapiens]
Length = 2624
Score = 30.0 bits (66), Expect = 9.5
Identities = 21/71 (29%), Positives = 32/71 (45%)
Query: 115 EESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVREIYGPHAVSLRE 174
E++R+ E E D + E Q N E+ ++E DL +RE L E
Sbjct: 1184 EKTREVIDAAEVIETDLEETEREISPQENGPEEVKPVGKMETDLKEIREEISQREKVLAE 1243
Query: 175 YGAIDDVDIDL 185
+ AI + +IDL
Sbjct: 1244 FSAIREKEIDL 1254
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,370,917
Number of Sequences: 37866
Number of extensions: 1518413
Number of successful extensions: 5427
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 5374
Number of HSP's gapped (non-prelim): 46
length of query: 854
length of database: 18,247,518
effective HSP length: 111
effective length of query: 743
effective length of database: 14,044,392
effective search space: 10434983256
effective search space used: 10434983256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.