Guide to the Human Genome
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Search of human proteins with 24431958

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
         (478 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24431958 solute carrier family 16, member 7 [Homo sapiens]         953   0.0  
gi|115583685 solute carrier family 16, member 1 [Homo sapiens]        574   e-164
gi|109288010 solute carrier family 16, member 3 [Homo sapiens]        411   e-115
gi|109288012 solute carrier family 16, member 3 [Homo sapiens]        411   e-115
gi|4759112 solute carrier family 16, member 3 [Homo sapiens]          411   e-115
gi|114796626 solute carrier family 16, member 8 [Homo sapiens]        403   e-112
gi|4759116 solute carrier family 16, member 5 [Homo sapiens]          291   9e-79
gi|157041233 solute carrier family 16 (monocarboxylic acid trans...   261   1e-69
gi|169217968 PREDICTED: similar to solute carrier family 16, mem...   240   2e-63
gi|42475555 monocarboxylate transporter 13 [Homo sapiens]             237   2e-62
gi|23503293 solute carrier family 16, member 11 [Homo sapiens]        234   2e-61
gi|40789261 solute carrier family 16, member 6 [Homo sapiens]         234   2e-61
gi|41327156 solute carrier family 16 (monocarboxylic acid transp...   179   4e-45
gi|4759114 solute carrier family 16, member 4 [Homo sapiens]          176   3e-44
gi|18699730 solute carrier family 16, member 10 [Homo sapiens]        174   2e-43
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]          167   1e-41
gi|34916028 solute carrier family 16 (monocarboxylic acid transp...   147   2e-35
gi|215272392 solute carrier family 18 (vesicular monoamine), mem...    41   0.003
gi|215272390 solute carrier family 18 (vesicular monoamine), mem...    41   0.003
gi|208879454 solute carrier family 18 (vesicular monoamine), mem...    41   0.003
gi|4506987 solute carrier family 18 (vesicular monoamine), membe...    41   0.003
gi|42476325 solute carrier family 18 (vesicular monoamine), memb...    36   0.088
gi|144953907 major facilitator superfamily domain containing 6 [...    35   0.20 
gi|24497499 solute carrier family 22 member 8 [Homo sapiens]           32   0.97 
gi|194239645 spinster homolog 3 [Homo sapiens]                         31   2.2  
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]     30   3.7  
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]     30   3.7  
gi|11386183 WAS protein family, member 2 [Homo sapiens]                30   3.7  
gi|190194386 transmembrane 9 superfamily member 3 [Homo sapiens]       30   4.8  
gi|90903231 huntingtin [Homo sapiens]                                  29   8.2  

>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
          Length = 478

 Score =  953 bits (2464), Expect = 0.0
 Identities = 478/478 (100%), Positives = 478/478 (100%)

Query: 1   MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW 60
           MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
Sbjct: 1   MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW 60

Query: 61  ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT 120
           ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
Sbjct: 61  ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT 120

Query: 121 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI 180
           GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
Sbjct: 121 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI 180

Query: 181 LGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS 240
           LGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS
Sbjct: 181 LGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS 240

Query: 241 LFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSV 300
           LFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSV
Sbjct: 241 LFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSV 300

Query: 301 GLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFE 360
           GLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFE
Sbjct: 301 GLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFE 360

Query: 361 TLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVW 420
           TLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVW
Sbjct: 361 TLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVW 420

Query: 421 LLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI 478
           LLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI
Sbjct: 421 LLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI 478


>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
          Length = 500

 Score =  574 bits (1479), Expect = e-164
 Identities = 285/465 (61%), Positives = 355/465 (76%), Gaps = 16/465 (3%)

Query: 1   MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW 60
           MPP    P  + PPDGGWGW VV  AFISIGFSYAFPK++TVFFKEI+ IFH T SE++W
Sbjct: 1   MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW 60

Query: 61  ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT 120
           ISSIMLAVMY GGP+SS+LVNKYGSR V+I GG L   G++ ASF ++V QLY+ +G I 
Sbjct: 61  ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG 120

Query: 121 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI 180
           GLGLAFNL PALT+IGKYFY++RP+ANGLAMAGSPVFL +LAP NQ  F  FGW+GSFLI
Sbjct: 121 GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI 180

Query: 181 LGSLLLNACVAGSLMRPLGPNQTTS---KSK------NKTGKTED--DSSPKKI-----K 224
           LG LLLN CVAG+LMRP+GP  T +   KSK       K+G  +D  D++   I     +
Sbjct: 181 LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ 240

Query: 225 TKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF 284
            K+S ++ +N++LD +LF HRGFL+YLSGNVIMF G FAP++FL+ Y K Q      +AF
Sbjct: 241 EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF 300

Query: 285 LLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYA 344
           LLS++AFVDM ARPS+GL+AN+K IRPRIQYFF+ +++ NGVCH+L PL+  Y    +YA
Sbjct: 301 LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA 360

Query: 345 VFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYK 404
            FFG  FG +SSVLFETLMDLVG  RFSSAVGLVTIVEC PVLLGPPL G+L D+ G+YK
Sbjct: 361 GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK 420

Query: 405 YMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESE 449
           Y Y +CG +++ + ++L IG  INYRLLAKE+K    +++++E E
Sbjct: 421 YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEE 465


>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score =  411 bits (1056), Expect = e-115
 Identities = 210/450 (46%), Positives = 288/450 (64%), Gaps = 24/450 (5%)

Query: 14  PDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGG 73
           PDGGWGW V+   F+  GFSYAFPKAV+VFFKE+ Q F   YS+ AWISSI+LA++Y  G
Sbjct: 16  PDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTG 75

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P+ SV VN++G RPV++ GGL   LGMV ASF  S++Q+YLT G ITGLGLA N QP+L 
Sbjct: 76  PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135

Query: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193
           ++ +YF ++RPMANGLA AGSPVFL +L+P  Q L + +GW+G FLILG LLLN CV  +
Sbjct: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195

Query: 194 LMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSG 253
           LMRPL                +  S P +            + LD S+F+ RGF++Y   
Sbjct: 196 LMRPL------------VVTAQPGSGPPR---------PSRRLLDLSVFRDRGFVLYAVA 234

Query: 254 NVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRI 313
             +M LG F P +F+  YAKD G+ +  AAFLL+++ F+D+FARP+ G +A    +RP  
Sbjct: 235 ASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYS 294

Query: 314 QYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSS 373
            Y FSF++ FNG+  L    A DY  LV++ +FFG+ +G V ++ FE LM +VG  +FSS
Sbjct: 295 VYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSS 354

Query: 374 AVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLA 433
           A+GLV ++E   VL+GPP  GKL+D T  Y Y+++  GA V+ +S+ LL+G   N+  + 
Sbjct: 355 AIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLG---NFFCIR 411

Query: 434 KERKEENARQKTRESEPLSKSKHSEDVNVK 463
           K+ KE        E E L K      V+++
Sbjct: 412 KKPKEPQPEVAAAEEEKLHKPPADSGVDLR 441


>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score =  411 bits (1056), Expect = e-115
 Identities = 210/450 (46%), Positives = 288/450 (64%), Gaps = 24/450 (5%)

Query: 14  PDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGG 73
           PDGGWGW V+   F+  GFSYAFPKAV+VFFKE+ Q F   YS+ AWISSI+LA++Y  G
Sbjct: 16  PDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTG 75

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P+ SV VN++G RPV++ GGL   LGMV ASF  S++Q+YLT G ITGLGLA N QP+L 
Sbjct: 76  PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135

Query: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193
           ++ +YF ++RPMANGLA AGSPVFL +L+P  Q L + +GW+G FLILG LLLN CV  +
Sbjct: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195

Query: 194 LMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSG 253
           LMRPL                +  S P +            + LD S+F+ RGF++Y   
Sbjct: 196 LMRPL------------VVTAQPGSGPPR---------PSRRLLDLSVFRDRGFVLYAVA 234

Query: 254 NVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRI 313
             +M LG F P +F+  YAKD G+ +  AAFLL+++ F+D+FARP+ G +A    +RP  
Sbjct: 235 ASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYS 294

Query: 314 QYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSS 373
            Y FSF++ FNG+  L    A DY  LV++ +FFG+ +G V ++ FE LM +VG  +FSS
Sbjct: 295 VYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSS 354

Query: 374 AVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLA 433
           A+GLV ++E   VL+GPP  GKL+D T  Y Y+++  GA V+ +S+ LL+G   N+  + 
Sbjct: 355 AIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLG---NFFCIR 411

Query: 434 KERKEENARQKTRESEPLSKSKHSEDVNVK 463
           K+ KE        E E L K      V+++
Sbjct: 412 KKPKEPQPEVAAAEEEKLHKPPADSGVDLR 441


>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score =  411 bits (1056), Expect = e-115
 Identities = 210/450 (46%), Positives = 288/450 (64%), Gaps = 24/450 (5%)

Query: 14  PDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGG 73
           PDGGWGW V+   F+  GFSYAFPKAV+VFFKE+ Q F   YS+ AWISSI+LA++Y  G
Sbjct: 16  PDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTG 75

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P+ SV VN++G RPV++ GGL   LGMV ASF  S++Q+YLT G ITGLGLA N QP+L 
Sbjct: 76  PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135

Query: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193
           ++ +YF ++RPMANGLA AGSPVFL +L+P  Q L + +GW+G FLILG LLLN CV  +
Sbjct: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195

Query: 194 LMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSG 253
           LMRPL                +  S P +            + LD S+F+ RGF++Y   
Sbjct: 196 LMRPL------------VVTAQPGSGPPR---------PSRRLLDLSVFRDRGFVLYAVA 234

Query: 254 NVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRI 313
             +M LG F P +F+  YAKD G+ +  AAFLL+++ F+D+FARP+ G +A    +RP  
Sbjct: 235 ASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYS 294

Query: 314 QYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSS 373
            Y FSF++ FNG+  L    A DY  LV++ +FFG+ +G V ++ FE LM +VG  +FSS
Sbjct: 295 VYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSS 354

Query: 374 AVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLA 433
           A+GLV ++E   VL+GPP  GKL+D T  Y Y+++  GA V+ +S+ LL+G   N+  + 
Sbjct: 355 AIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLG---NFFCIR 411

Query: 434 KERKEENARQKTRESEPLSKSKHSEDVNVK 463
           K+ KE        E E L K      V+++
Sbjct: 412 KKPKEPQPEVAAAEEEKLHKPPADSGVDLR 441


>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
          Length = 504

 Score =  403 bits (1035), Expect = e-112
 Identities = 198/418 (47%), Positives = 278/418 (66%), Gaps = 7/418 (1%)

Query: 13  PPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAG 72
           PPDGGWGW+V+GA F+  GF+Y FPKAV+VFF+ + + F   YS+ AW+SSIMLA++Y  
Sbjct: 12  PPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGT 71

Query: 73  GPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPAL 132
           GPVSS+LV ++G RPV++AGGLL   GM+LASF++ +++LYLT G +TGLGLA N QP+L
Sbjct: 72  GPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSL 131

Query: 133 TIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAG 192
            ++G YF R+RP+ANGLA AGSPVFLS+L+P  Q L   FGW+G FL+LG LLL+ C  G
Sbjct: 132 IMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACG 191

Query: 193 SLMR-PLGP------NQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHR 245
           ++MR P GP      +    ++ +  G+ E D +  +++          + LD ++   R
Sbjct: 192 AVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDR 251

Query: 246 GFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIAN 305
            F +Y     +M LG F P I L  YAKD G+ +  AAFLLS++ FVD+ ARP+ G +A 
Sbjct: 252 AFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAG 311

Query: 306 SKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDL 365
              +RP + Y FS A++ NG+  L    A+ Y +LV + V FGL +G V ++ FE LM  
Sbjct: 312 LARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAA 371

Query: 366 VGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLI 423
           VGAPRF SA+GLV +VE   VL+GPP AG+LVD+   Y+ ++   G+ V  A V++ +
Sbjct: 372 VGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAV 429


>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
          Length = 505

 Score =  291 bits (745), Expect = 9e-79
 Identities = 152/443 (34%), Positives = 255/443 (57%), Gaps = 10/443 (2%)

Query: 15  DGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGGP 74
           DG W W+V+ A  ++ G +  FP  + +FF E+Q  F  + SE +W  SI+ AV++  GP
Sbjct: 9   DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGP 68

Query: 75  VSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTI 134
           + S+LV ++G R  V+ GG+L  LGMV +SFS ++ QLY T GFITGLG+ F+ Q ++T+
Sbjct: 69  LCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITV 128

Query: 135 IGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSL 194
           +G YF R+R +AN LA  G  + ++     ++YL    GW+G+FL+ G + L+ C+ G++
Sbjct: 129 LGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAI 188

Query: 195 MRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHR-GFLIYLSG 253
           +RP+    T+   + K        +P  +    +    + ++L F + +H  G+ +Y+ G
Sbjct: 189 IRPVA---TSVAPETKECPPPPPETP-ALGCLAACGRTIQRHLAFDILRHNTGYCVYILG 244

Query: 254 NVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRI 313
            +   LGF  P +FL PYA    +DE  AA L+S++ F ++F RP  GL+A         
Sbjct: 245 VMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHR 304

Query: 314 QYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSS 373
           +Y FS A++ NG+ +L+C  + D+  LV Y + + +    + +++F+ LMD+V   +F  
Sbjct: 305 KYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPR 364

Query: 374 AVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYM-YMSCGAIVVAASVWLLIGNAINYRLL 432
           A+GL T+++    L+ PPLAG L+D T  + Y+ YMS   ++ AA   L +G +  Y L 
Sbjct: 365 ALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAA---LFMGGSF-YALQ 420

Query: 433 AKERKEENARQKTRESEPLSKSK 455
            KE+ ++       E +   ++K
Sbjct: 421 KKEQGKQAVAADALERDLFLEAK 443


>gi|157041233 solute carrier family 16 (monocarboxylic acid
           transporters), member 12 [Homo sapiens]
          Length = 486

 Score =  261 bits (667), Expect = 1e-69
 Identities = 147/445 (33%), Positives = 243/445 (54%), Gaps = 13/445 (2%)

Query: 13  PPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAG 72
           PPDGGWGW++V   F+    + A  + +++FF E Q  F   Y++ AWI SI+  V    
Sbjct: 12  PPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLC 71

Query: 73  GPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPAL 132
            P+ SV+ N    +  ++ GGLL   G++L+SF++S+  LYLT+G +TGLG A    PA+
Sbjct: 72  APLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAI 131

Query: 133 TIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAG 192
            ++GKYF R++ +A G+AM+GS +    LAP  Q L   F W+G+ LILG  +LN CV G
Sbjct: 132 AMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCG 191

Query: 193 SLMRPLGPNQT-TSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYL------DFSLFKHR 245
           +LMRP+   +  T+  +N   +T+ +   +       T E     L      ++S     
Sbjct: 192 ALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMS 251

Query: 246 GFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIAN 305
            F++     + M  G     ++L PYA   G+    AAFL+S++  +D+    + G + +
Sbjct: 252 DFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTD 311

Query: 306 SKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDL 365
            + ++      + FA+  +G+C+L  P+ Q    LV ++  FG   G+  +++     ++
Sbjct: 312 RRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEI 371

Query: 366 VGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGN 425
           VG    SSA+G+V  +   P L+ PP+AG+LVD TG Y   ++ CG  ++ +SV  L+G 
Sbjct: 372 VGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSV--LLGF 429

Query: 426 AINYRLLAKERKEENARQKTRESEP 450
           A   RL+ + RK +  +   +ES+P
Sbjct: 430 A---RLIKRMRKTQ-LQFIAKESDP 450


>gi|169217968 PREDICTED: similar to solute carrier family 16, member
           5 [Homo sapiens]
          Length = 453

 Score =  240 bits (612), Expect = 2e-63
 Identities = 130/384 (33%), Positives = 220/384 (57%), Gaps = 10/384 (2%)

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P+ S+LV ++G R  V+ GG+L  LGMV +SFS ++ QLY T GFITGLG+ F+ Q ++T
Sbjct: 16  PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75

Query: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193
           ++G YF R+R +AN LA  G  + ++     ++YL    GW+G+FL+ G + L+ C+ G+
Sbjct: 76  VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135

Query: 194 LMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHR-GFLIYLS 252
           ++RP+    T+   + K        +P  +    +    + ++L F + +H  G+ +Y+ 
Sbjct: 136 IIRPVA---TSVAPETKECPPPPPETPA-LGCLAACGRTIQRHLAFDILRHNTGYCVYIL 191

Query: 253 GNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPR 312
           G +   LGF  P +FL PYA    +DE  AA L+S++ F ++F RP  GL+A        
Sbjct: 192 GVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASH 251

Query: 313 IQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFS 372
            +Y FS A++ NG+ +L+C  + D+  LV Y + + +    + +++F+ LMD+V   +F 
Sbjct: 252 RKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFP 311

Query: 373 SAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYM-YMSCGAIVVAASVWLLIGNAINYRL 431
            A+GL T+++    L+ PPLAG L+D T  + Y+ YMS   ++ AA   L +G +  Y L
Sbjct: 312 RALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAA---LFMGGSF-YAL 367

Query: 432 LAKERKEENARQKTRESEPLSKSK 455
             KE+ ++       E +   ++K
Sbjct: 368 QKKEQGKQAVAADALERDLFLEAK 391


>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
          Length = 426

 Score =  237 bits (604), Expect = 2e-62
 Identities = 140/410 (34%), Positives = 213/410 (51%), Gaps = 27/410 (6%)

Query: 13  PPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAG 72
           PPDGGWGW+VV +AF      +   ++  VFF E    F    + ++WI+SI +AV   G
Sbjct: 7   PPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFG 66

Query: 73  GPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPAL 132
            PV S L  K+G RPVV+ GG+L  LGM+LASF++S+  LYL++G ++G G A    P L
Sbjct: 67  SPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTL 126

Query: 133 TIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAG 192
             +  YF R+R +A GLA+ G  +   + APF Q+L + + W+GS L++ +L L+    G
Sbjct: 127 ACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACG 186

Query: 193 SLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLS 252
           +L+RP    +  +    +   T                         SL  H  FL Y  
Sbjct: 187 ALLRPPSLAEDPAVGGPRAQLT-------------------------SLLHHGPFLRYTV 221

Query: 253 GNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPR 312
              ++  G+F P + L  + +D   D   AAFLLSV+A  D+  R   G + ++  +   
Sbjct: 222 ALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDA--VPGP 279

Query: 313 IQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFS 372
           +           GV   L P+AQ  T+LV  AV +G   G+++ + F  L +L+G  R  
Sbjct: 280 VTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIY 339

Query: 373 SAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLL 422
             +GL+ ++E    LLGPPL+G L D+TG Y   ++  GA +++ S  LL
Sbjct: 340 CGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILL 389


>gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
          Length = 471

 Score =  234 bits (596), Expect = 2e-61
 Identities = 144/423 (34%), Positives = 220/423 (52%), Gaps = 29/423 (6%)

Query: 2   PPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWI 61
           P     P    PPDGGWGW+V  AAF   G SY   +++ + F ++ + F  +  + AWI
Sbjct: 21  PQTAMTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWI 80

Query: 62  SSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITG 121
           S++ LAV  A  PV S L  ++G+RPVV+ GG+L  LG V ++F+S ++ LYL +G + G
Sbjct: 81  SALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAG 140

Query: 122 LGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLIL 181
            G A    PAL  + +YF R+R +A GLA+ G+      LAP  Q L +TFGW+G+ L+L
Sbjct: 141 FGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLL 200

Query: 182 GSLLLNACVAGSLMRPLG-PNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS 240
           G++ L+    G+L+ PL  P    +  ++                           L  S
Sbjct: 201 GAITLHLTPCGALLLPLVLPGDPPAPPRSPLAA-----------------------LGLS 237

Query: 241 LFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSV 300
           LF  R F I+  G  ++  G+F P + LAP+A D+G+  Y AA +++V A  D  AR   
Sbjct: 238 LFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVC 297

Query: 301 GLIANSKYI-RPRIQYFFSFAIMFNGVCHLLCPLAQDYTS----LVLYAVFFGLGFGSVS 355
           G +A+  ++  PR+   F            L P+     S    L+  AV +GL  GS +
Sbjct: 298 GWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYA 357

Query: 356 SVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVV 415
            ++F  L  LVG      A GLV ++     LLGPPL+G L D TG++   ++  G++++
Sbjct: 358 PLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLIL 417

Query: 416 AAS 418
           + S
Sbjct: 418 SGS 420


>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
          Length = 523

 Score =  234 bits (596), Expect = 2e-61
 Identities = 160/505 (31%), Positives = 238/505 (47%), Gaps = 57/505 (11%)

Query: 14  PDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGG 73
           PDGGWGW V  + F    F+Y   K   VFF ++   F+ + S I+WI SI + V+    
Sbjct: 19  PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSA 78

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P+++VL N++G R VV+ GGLL   GMV ASFS  V  +Y+ +G I+GLG  F+  P +T
Sbjct: 79  PLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVT 138

Query: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193
           I+ +YF ++R +   +A  G    + + AP    L    GW+ S L +G L LN  + G+
Sbjct: 139 ILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGA 198

Query: 194 LMRPL---GPN---------------------------------QTTSKSKNKTGKTEDD 217
           L+RP+   GP                                  + T+  KN    T  +
Sbjct: 199 LLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLE 258

Query: 218 SSPKK------IKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPY 271
             PK       +KT     EK    LDFS+ K + F+ Y    +   LGFFAP +++ P 
Sbjct: 259 LEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIPL 318

Query: 272 AKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLC 331
               GID+  AAFLLS MA  ++F R   G + N + IR    Y     ++   V     
Sbjct: 319 GISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRK--IYIELICVILLTVSLFAF 376

Query: 332 PLAQDYTSLVLYAVFFGLGFGSVSSVLFETLM--DLVGAPRFSSAVGLVTIVECGPVLLG 389
             A ++  L+  ++FFG   G++       L   D+VG  + SSA G+   ++    L G
Sbjct: 377 TFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAG 436

Query: 390 PPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLL----AKERKEENARQKT 445
           PPLAG LVD +  Y   + SC A +  A+V L +       L     + E K  + R KT
Sbjct: 437 PPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKT 496

Query: 446 RESEP-------LSKSKHSEDVNVK 463
            +  P       L+K++H   V ++
Sbjct: 497 LQDIPEDFLEMDLAKNEHRVHVQME 521


>gi|41327156 solute carrier family 16 (monocarboxylic acid
           transporters), member 14 [Homo sapiens]
          Length = 510

 Score =  179 bits (455), Expect = 4e-45
 Identities = 132/486 (27%), Positives = 220/486 (45%), Gaps = 65/486 (13%)

Query: 11  HPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMY 70
           HP  DGGW W++V ++F           A+ V   E  + FH +    AW+SS+ + +  
Sbjct: 25  HPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITL 84

Query: 71  AGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQP 130
             GP   + +N  G R   I GGL+  LG VL++++++V  L++T G   GLG      P
Sbjct: 85  IVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLP 144

Query: 131 ALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACV 190
           A+ ++G+YF ++R +A GL+  G+      +    +YL   +GW+ + LI G++ LN CV
Sbjct: 145 AVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCV 204

Query: 191 AGSLMRPLGPNQTTS------------------KSKNKTGKTE----------------- 215
            G+LMRPL P +  +                  KS  + G+TE                 
Sbjct: 205 CGALMRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQA 264

Query: 216 ----DDSSPKK-------IKTKKSTWEKVNKYLD---------FSLFKHRGFLIYLSGNV 255
               D +  +K       +KT      +V K  +          SLF +R F+ ++   +
Sbjct: 265 QECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWAL 324

Query: 256 IMFLGFFAPIIFLAPYAKDQGIDEYSAAF-LLSVMAFVDMFARPSVGLIANSKYIRPRIQ 314
             +  F  P I L        + E +  F L S++A V +F +  +G+IA+   I   + 
Sbjct: 325 FAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCI--SVW 382

Query: 315 YFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGL--GFGSVSSVLFETLMDLVGAPRFS 372
             F  A     +   + PL   Y  L +     G   G+ S+  V+ E   DLVG    +
Sbjct: 383 NVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVVTE---DLVGIEHLA 439

Query: 373 SAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLL 432
           +A G++        LLGPP AG + D+T +Y + +  CG + +   ++LLI   I  R++
Sbjct: 440 NAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQPCI--RII 497

Query: 433 AKERKE 438
            + R++
Sbjct: 498 EQSRRK 503


>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
          Length = 487

 Score =  176 bits (447), Expect = 3e-44
 Identities = 125/461 (27%), Positives = 211/461 (45%), Gaps = 61/461 (13%)

Query: 15  DGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGGP 74
           DGGWGW++V   F+   F     K   +FF   Q+ F  T  +I WI SIM ++ +  GP
Sbjct: 16  DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGP 75

Query: 75  VSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTI 134
           + +++ +  G +   I G  +   G +++S+++S+  L +TMG + GLG AF  Q A  +
Sbjct: 76  LVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVV 135

Query: 135 IGKYFYRKRPMANGLAMAGSPV-FLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193
             KYF ++  ++  +A +G  + FL  LAPF ++L + + W G+ ++ G++ LN   +  
Sbjct: 136 TTKYFKKRLALSTAIARSGMGLTFL--LAPFTKFLIDLYDWTGALILFGAIALNLVPSSM 193

Query: 194 LMRPL--------------------GPN--------QTTSKSKNKTGKTEDDSSPKKIKT 225
           L+RP+                    GP           T +S  K   T+    P K  T
Sbjct: 194 LLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLT 253

Query: 226 ---------------------------KKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMF 258
                                      K  +W    +  D SLF++  F I+    ++  
Sbjct: 254 VSQNQSEEFYNGPNRNRLLLKSDEESDKVISW-SCKQLFDISLFRNPFFYIFTWSFLLSQ 312

Query: 259 LGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFS 318
           L +F P   L   AK  GID   A++L+SV   ++  ++   G +A+  +I+ +  Y  S
Sbjct: 313 LAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIK-KYHYHKS 371

Query: 319 FAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLV 378
           + I+  G+ +LL PLA  +  L+ Y + F +  G   +++   L+DL      +  +GL 
Sbjct: 372 YLILC-GITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLA 430

Query: 379 TIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASV 419
           +      VL GPP+AG L D T  Y   +   G   + +SV
Sbjct: 431 SFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSV 471


>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
          Length = 515

 Score =  174 bits (441), Expect = 2e-43
 Identities = 127/462 (27%), Positives = 211/462 (45%), Gaps = 29/462 (6%)

Query: 5   PSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSE-----IA 59
           P  PP   PP+GGWGW+V+ AA    G  +    A  V F  + + F +   +      A
Sbjct: 58  PHEPP--EPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTA 115

Query: 60  WISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFI 119
           W+ S+ + +++   P+ SV  + +G R   + G  +  +G++ +SF SS+  LYLT G I
Sbjct: 116 WVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGII 175

Query: 120 TGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFL 179
              G +F  QP+L I+G YF ++  + NG+  AGS VF   L    + L ++ G   +  
Sbjct: 176 FACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLR 235

Query: 180 ILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDF 239
           +L   +    +AG   RPL    T++K K   G      S KK    K       K  +F
Sbjct: 236 VLCIFMFVLFLAGFTYRPLA---TSTKDKESGGSGSSLFSRKKFSPPK-------KIFNF 285

Query: 240 SLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPS 299
           ++FK   + ++  G  +   G+F P + L  +  ++  DE +   +L  +       R  
Sbjct: 286 AIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLL 345

Query: 300 VGLIANSKYIRPRIQ--YFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSV 357
            G IA+  Y+ P ++  Y    +  F G+  ++ PL   + +L+   +  GL  G   S+
Sbjct: 346 FGRIAD--YV-PGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISI 402

Query: 358 LFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAA 417
           +     +LVGA   S A+G +      P+ +GPP+AG L D  G Y   +   G      
Sbjct: 403 MAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAG------ 456

Query: 418 SVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSED 459
            V  LIG A+   +     K++    KT   E + K   +++
Sbjct: 457 -VPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQN 497


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score =  167 bits (424), Expect = 1e-41
 Identities = 108/433 (24%), Positives = 208/433 (48%), Gaps = 18/433 (4%)

Query: 13  PPDGGWGWIVVGAAFISIGFSYAFPKAVTVFF----KEIQQIFHTTYSEIAWISSIMLAV 68
           PP+GG+GW+VV AA    G  +    +V + +    +E ++       + AW+ ++ + +
Sbjct: 168 PPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGM 227

Query: 69  MYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNL 128
           ++   P+ S+  ++ G R    AG  +  +G+  +SF+SS+   Y T G + G G +F  
Sbjct: 228 IFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAF 287

Query: 129 QPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNA 188
           QP+L I+G YF R+  +ANG+  AGS +F  S     + L +      +F +L + +   
Sbjct: 288 QPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVL 347

Query: 189 CVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTW-EKVNKYLDFSLFKHRGF 247
            +     RPL P+            ++D  S + ++T    +  ++ KY +  +F+ R +
Sbjct: 348 MLLSLTYRPLLPS------------SQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTY 395

Query: 248 LIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSK 307
            I+  G     LG+F P + L  Y +++  +      LL  +       R   G I++S 
Sbjct: 396 RIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISDSI 455

Query: 308 YIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVG 367
               +I Y    + +  G+  ++ PL +D+  L++  +F GL  G   +++     +LVG
Sbjct: 456 PGLKKI-YLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVG 514

Query: 368 APRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAI 427
             + S A+G +  +   P++ GPP+AG L +  G+Y   +   G   +  +V L     +
Sbjct: 515 PMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLM 574

Query: 428 NYRLLAKERKEEN 440
           + R+  KE+++ +
Sbjct: 575 HQRMFKKEQRDSS 587


>gi|34916028 solute carrier family 16 (monocarboxylic acid
           transporters), member 9 [Homo sapiens]
          Length = 509

 Score =  147 bits (372), Expect = 2e-35
 Identities = 120/477 (25%), Positives = 195/477 (40%), Gaps = 70/477 (14%)

Query: 14  PDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGG 73
           PDGGWGW++V  +F++    Y  P AV V + E    F     + AW+ S+   V     
Sbjct: 7   PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           PV S+ V+ +G+RPV I  G +   G++L+SF+ ++  L+ + G + GLG        +T
Sbjct: 67  PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126

Query: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193
           I  +YF  +R +A GL   GS V L   A   + L   +G  G  LI+G+L LN    GS
Sbjct: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186

Query: 194 LM-----------RPLGPNQTTSKSK--NKTGKTEDDS---------------------- 218
           LM           + + P     K    N+ GK  +++                      
Sbjct: 187 LMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGD 246

Query: 219 -----------------SPKKIKTK------------KSTWEKVNKYLD--FSLFKHRGF 247
                             P+  K K            K  W+    Y     +LFK++ F
Sbjct: 247 WKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVF 306

Query: 248 LIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF-LLSVMAFVDMFARPSVGLIANS 306
                  ++  +G F P + +   A+   + E      L+S++  +    +  +G++A+ 
Sbjct: 307 SALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADF 366

Query: 307 KYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLV 366
           K+I     Y  +  IM   +C +  P A+ Y +L L +   G   G+ S   + T    V
Sbjct: 367 KWINTLYLYVATLIIMGLALCAI--PFAKSYVTLALLSGILGFLTGNWSIFPYVT-TKTV 423

Query: 367 GAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLI 423
           G  + + A G++         LGPP+ G   D T  Y   +   G  V+     LL+
Sbjct: 424 GIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480


>gi|215272392 solute carrier family 18 (vesicular monoamine), member
           1 isoform c [Homo sapiens]
          Length = 472

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 4/127 (3%)

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P    L N+ G    + AG ++  L  V+ +FS +   L++    + G+G +F+    L 
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVART-LQGIGSSFSSVAGLG 213

Query: 134 IIGKYFY--RKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSL-LLNACV 190
           ++   +    +R  A G A+ G  + L   APF   ++   G    FLIL  L LL+  +
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGAL 273

Query: 191 AGSLMRP 197
              +++P
Sbjct: 274 QLCILQP 280


>gi|215272390 solute carrier family 18 (vesicular monoamine), member
           1 isoform b [Homo sapiens]
          Length = 493

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 4/127 (3%)

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P    L N+ G    + AG ++  L  V+ +FS +   L++    + G+G +F+    L 
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVART-LQGIGSSFSSVAGLG 213

Query: 134 IIGKYFY--RKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSL-LLNACV 190
           ++   +    +R  A G A+ G  + L   APF   ++   G    FLIL  L LL+  +
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGAL 273

Query: 191 AGSLMRP 197
              +++P
Sbjct: 274 QLCILQP 280


>gi|208879454 solute carrier family 18 (vesicular monoamine), member
           1 isoform a [Homo sapiens]
          Length = 525

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 4/127 (3%)

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P    L N+ G    + AG ++  L  V+ +FS +   L++    + G+G +F+    L 
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVART-LQGIGSSFSSVAGLG 213

Query: 134 IIGKYFY--RKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSL-LLNACV 190
           ++   +    +R  A G A+ G  + L   APF   ++   G    FLIL  L LL+  +
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGAL 273

Query: 191 AGSLMRP 197
              +++P
Sbjct: 274 QLCILQP 280


>gi|4506987 solute carrier family 18 (vesicular monoamine), member 1
           isoform a [Homo sapiens]
          Length = 525

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 4/127 (3%)

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P    L N+ G    + AG ++  L  V+ +FS +   L++    + G+G +F+    L 
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVART-LQGIGSSFSSVAGLG 213

Query: 134 IIGKYFY--RKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSL-LLNACV 190
           ++   +    +R  A G A+ G  + L   APF   ++   G    FLIL  L LL+  +
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGAL 273

Query: 191 AGSLMRP 197
              +++P
Sbjct: 274 QLCILQP 280


>gi|42476325 solute carrier family 18 (vesicular monoamine), member
           2 [Homo sapiens]
          Length = 514

 Score = 35.8 bits (81), Expect = 0.088
 Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 3/115 (2%)

Query: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
           P   +L N+ G    + AG  +  +  ++ +FSSS   L +    + G+G + +    + 
Sbjct: 147 PFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARS-LQGIGSSCSSVAGMG 205

Query: 134 IIGKYFYRKRPMAN--GLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLL 186
           ++   +       N  G+A+ G  + +    PF   L+   G    FL+L +L+L
Sbjct: 206 MLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVL 260



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 15/175 (8%)

Query: 273 KDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCP 332
           KD   +      L +  A V +   P +GL+ N   I   I  F  F IMF  V  ++  
Sbjct: 122 KDLLNENVQVGLLFASKATVQLITNPFIGLLTNR--IGYPIPIFAGFCIMF--VSTIMFA 177

Query: 333 LAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAP--RFSSAVGLVTIVECGPVLLGP 390
            +  Y  L++     G+G  S SSV    ++  V        + +G+        VL+GP
Sbjct: 178 FSSSYAFLLIARSLQGIG-SSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGP 236

Query: 391 PLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKT 445
           P    L      Y+++  +   +V+AA V  L+  AI   +L   R +  +++ T
Sbjct: 237 PFGSVL------YEFVGKTAPFLVLAALV--LLDGAIQLFVLQPSRVQPESQKGT 283


>gi|144953907 major facilitator superfamily domain containing 6
           [Homo sapiens]
          Length = 791

 Score = 34.7 bits (78), Expect = 0.20
 Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%)

Query: 318 SFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGL 377
           S A  F  +  LLC +   Y S++  A F G G+G V + L+  L DL G    ++  G+
Sbjct: 430 SQAFNFWDLIKLLCSV--QYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGT---TTLFGV 484

Query: 378 VTIVECGPVLLGPPLAGKLVDLTGEYKYMYM 408
            +++     L     + KL++L G  + +Y+
Sbjct: 485 CSVLSHVSELTAYFFSHKLIELIGHIRVLYI 515


>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
          Length = 542

 Score = 32.3 bits (72), Expect = 0.97
 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)

Query: 63  SIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGL 122
           SI +A +  GG V   L +++G RP++    LL       A+FS +   +Y+   F+ G 
Sbjct: 127 SIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPT-FPIYMVFRFLCGF 185

Query: 123 GLA 125
           G++
Sbjct: 186 GIS 188


>gi|194239645 spinster homolog 3 [Homo sapiens]
          Length = 512

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 35/148 (23%), Positives = 59/148 (39%), Gaps = 12/148 (8%)

Query: 2   PPMPSAPPVHP-----PPDGGWGWIVVGAAFISIGF-SYAFPKAVTVFFKEIQQIFHTTY 55
           P     PP+ P     PP   W   V  A    I   +Y     +     +IQ++F  + 
Sbjct: 24  PGRQCPPPITPTSWSLPP---WRAYVAAAVLCYINLLNYMNWFIIAGVLLDIQEVFQISD 80

Query: 56  SEIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLAS--FSSSVVQLY 113
           +    + ++ ++ +    PV   L +++ SR   ++ G+L   G  L+S   S     L+
Sbjct: 81  NHAGLLQTVFVSCLLLSAPVFGYLGDRH-SRKATMSFGILLWSGAGLSSSFISPRYSWLF 139

Query: 114 LTMGFITGLGLAFNLQPALTIIGKYFYR 141
                I G G A     A T++G  F R
Sbjct: 140 FLSRGIVGTGSASYSTIAPTVLGDLFVR 167


>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
          Length = 613

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)

Query: 231 EKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMA 290
           E + K +D  +F    F++YL   VI    F  P+IF    AK    ++YS  F + +  
Sbjct: 279 EHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIF----AKIIRYEDYSPGFEIRLTI 334

Query: 291 FVDMFAR 297
              +F R
Sbjct: 335 LRCVFMR 341


>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
          Length = 723

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)

Query: 231 EKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMA 290
           E + K +D  +F    F++YL   VI    F  P+IF    AK    ++YS  F + +  
Sbjct: 389 EHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIF----AKIIRYEDYSPGFEIRLTI 444

Query: 291 FVDMFAR 297
              +F R
Sbjct: 445 LRCVFMR 451


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 13/63 (20%)

Query: 206 KSKNKTGKTEDDS------SPKKIKTKKSTWEKVNKYLDFSLFKHR----GF---LIYLS 252
           K K K  K + D+      +P+KIKT+K  WEK+    +F   K +    G+   L+Y +
Sbjct: 173 KEKRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQN 232

Query: 253 GNV 255
           G++
Sbjct: 233 GSI 235


>gi|190194386 transmembrane 9 superfamily member 3 [Homo sapiens]
          Length = 589

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 12/88 (13%)

Query: 204 TSKSKNKTGKTEDDSSPKKIKTKKSTW---EKVNKYLDFSLFKHR--GFLIYLSGNVIMF 258
           TS+ K K            +K KKS     ++ +KYLD S F+HR   F I+ S  +++F
Sbjct: 176 TSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIF 235

Query: 259 LGFFAPIIFL-------APYAKDQGIDE 279
           L     +I +       A Y+K++ +D+
Sbjct: 236 LVGLVSMILMRTLRKDYARYSKEEEMDD 263


>gi|90903231 huntingtin [Homo sapiens]
          Length = 3144

 Score = 29.3 bits (64), Expect = 8.2
 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 2/81 (2%)

Query: 271 YAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLL 330
           +A D  I     AF+ ++ +      R + G   +      R QYF+S+  + N +  LL
Sbjct: 244 FANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAVSICQHSRRTQYFYSW--LLNVLLGLL 301

Query: 331 CPLAQDYTSLVLYAVFFGLGF 351
            P+  ++++L++  V   L +
Sbjct: 302 VPVEDEHSTLLILGVLLTLRY 322


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,726,014
Number of Sequences: 37866
Number of extensions: 767351
Number of successful extensions: 4102
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 4047
Number of HSP's gapped (non-prelim): 53
length of query: 478
length of database: 18,247,518
effective HSP length: 106
effective length of query: 372
effective length of database: 14,233,722
effective search space: 5294944584
effective search space used: 5294944584
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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