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Search of human proteins with 24430141
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24430141 fibrillin 1 precursor [Homo sapiens]
(2871 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24430141 fibrillin 1 precursor [Homo sapiens] 6416 0.0
gi|66346695 fibrillin 2 precursor [Homo sapiens] 4586 0.0
gi|56237021 fibrillin 3 precursor [Homo sapiens] 3984 0.0
gi|110347437 latent transforming growth factor beta binding prot... 547 e-155
gi|110347412 latent transforming growth factor beta binding prot... 547 e-155
gi|110347431 latent transforming growth factor beta binding prot... 547 e-155
gi|24041035 notch 2 preproprotein [Homo sapiens] 516 e-145
gi|4557733 latent transforming growth factor beta binding protei... 508 e-143
gi|46249414 latent transforming growth factor beta binding prote... 504 e-142
gi|46249412 latent transforming growth factor beta binding prote... 504 e-142
gi|148833508 notch1 preproprotein [Homo sapiens] 481 e-135
gi|134244285 Notch homolog 3 [Homo sapiens] 443 e-123
gi|18497288 latent transforming growth factor beta binding prote... 429 e-119
gi|194328809 latent transforming growth factor beta binding prot... 419 e-116
gi|55770876 notch4 preproprotein [Homo sapiens] 334 9e-91
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 295 6e-79
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 291 5e-78
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 276 2e-73
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 249 3e-65
gi|34734066 fibulin 1 isoform D [Homo sapiens] 245 4e-64
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 245 5e-64
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 245 5e-64
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 244 7e-64
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 244 7e-64
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 244 7e-64
gi|118572606 hemicentin 1 [Homo sapiens] 242 4e-63
gi|10190748 CEGP1 protein [Homo sapiens] 220 1e-56
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 220 2e-56
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 217 2e-55
gi|4557679 jagged 1 precursor [Homo sapiens] 214 1e-54
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 6416 bits (16646), Expect = 0.0
Identities = 2871/2871 (100%), Positives = 2871/2871 (100%)
Query: 1 MRRGRLLEIALGFTVLLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCG 60
MRRGRLLEIALGFTVLLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCG
Sbjct: 1 MRRGRLLEIALGFTVLLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCG 60
Query: 61 SRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCN 120
SRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCN
Sbjct: 61 SRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCN 120
Query: 121 IRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERD 180
IRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERD
Sbjct: 121 IRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERD 180
Query: 181 YRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIR 240
YRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIR
Sbjct: 181 YRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIR 240
Query: 241 TGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICE 300
TGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICE
Sbjct: 241 TGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICE 300
Query: 301 GGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCC 360
GGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCC
Sbjct: 301 GGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCC 360
Query: 361 DAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFP 420
DAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFP
Sbjct: 361 DAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFP 420
Query: 421 PGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGF 480
PGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGF
Sbjct: 421 PGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGF 480
Query: 481 QLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRI 540
QLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRI
Sbjct: 481 QLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRI 540
Query: 541 CNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKP 600
CNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKP
Sbjct: 541 CNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKP 600
Query: 601 GFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRST 660
GFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRST
Sbjct: 601 GFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRST 660
Query: 661 CYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSA 720
CYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSA
Sbjct: 661 CYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSA 720
Query: 721 GSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ 780
GSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ
Sbjct: 721 GSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ 780
Query: 781 CRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDP 840
CRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDP
Sbjct: 781 CRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDP 840
Query: 841 TKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGY 900
TKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGY
Sbjct: 841 TKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGY 900
Query: 901 SRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFL 960
SRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFL
Sbjct: 901 SRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFL 960
Query: 961 RYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEIT 1020
RYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEIT
Sbjct: 961 RYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEIT 1020
Query: 1021 NGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL 1080
NGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL
Sbjct: 1021 NGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL 1080
Query: 1081 CGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCEC 1140
CGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCEC
Sbjct: 1081 CGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCEC 1140
Query: 1141 PPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200
PPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE
Sbjct: 1141 PPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200
Query: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE 1260
CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE
Sbjct: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE 1260
Query: 1261 YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC 1320
YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC
Sbjct: 1261 YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC 1320
Query: 1321 TDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADC 1380
TDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADC
Sbjct: 1321 TDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADC 1380
Query: 1381 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD 1440
KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD
Sbjct: 1381 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD 1440
Query: 1441 GKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISG 1500
GKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISG
Sbjct: 1441 GKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISG 1500
Query: 1501 NCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA 1560
NCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA
Sbjct: 1501 NCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA 1560
Query: 1561 SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGG 1620
SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGG
Sbjct: 1561 SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGG 1620
Query: 1621 KCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQ 1680
KCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQ
Sbjct: 1621 KCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQ 1680
Query: 1681 VNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPS 1740
VNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPS
Sbjct: 1681 VNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPS 1740
Query: 1741 TDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYN 1800
TDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYN
Sbjct: 1741 TDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYN 1800
Query: 1801 DKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC 1860
DKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC
Sbjct: 1801 DKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC 1860
Query: 1861 SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGF 1920
SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGF
Sbjct: 1861 SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGF 1920
Query: 1921 ILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLE 1980
ILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLE
Sbjct: 1921 ILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLE 1980
Query: 1981 PRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLC 2040
PRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLC
Sbjct: 1981 PRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLC 2040
Query: 2041 PEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCP 2100
PEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCP
Sbjct: 2041 PEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCP 2100
Query: 2101 TEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA 2160
TEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA
Sbjct: 2101 TEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA 2160
Query: 2161 GNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR 2220
GNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR
Sbjct: 2161 GNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR 2220
Query: 2221 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGY 2280
CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGY
Sbjct: 2221 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGY 2280
Query: 2281 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCF 2340
QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCF
Sbjct: 2281 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCF 2340
Query: 2341 TEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG 2400
TEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG
Sbjct: 2341 TEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG 2400
Query: 2401 ADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICK 2460
ADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICK
Sbjct: 2401 ADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICK 2460
Query: 2461 NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHT 2520
NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHT
Sbjct: 2461 NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHT 2520
Query: 2521 SCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHG 2580
SCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHG
Sbjct: 2521 SCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHG 2580
Query: 2581 CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYE 2640
CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYE
Sbjct: 2581 CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYE 2640
Query: 2641 QFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPP 2700
QFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPP
Sbjct: 2641 QFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPP 2700
Query: 2701 VSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASNIEDQSETEANVSLASWDVEK 2760
VSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASNIEDQSETEANVSLASWDVEK
Sbjct: 2701 VSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASNIEDQSETEANVSLASWDVEK 2760
Query: 2761 TAIFAFNISHVSNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKK 2820
TAIFAFNISHVSNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKK
Sbjct: 2761 TAIFAFNISHVSNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKK 2820
Query: 2821 KPVAGTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH 2871
KPVAGTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH
Sbjct: 2821 KPVAGTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH 2871
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 4586 bits (11896), Expect = 0.0
Identities = 1972/2867 (68%), Positives = 2342/2867 (81%), Gaps = 59/2867 (2%)
Query: 39 ASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPN 98
ASR +RRG D L+GPNVCGSR+++YCCPGWKTLPGGNQCIVPICR+SCGDGFCSRPN
Sbjct: 71 ASRVRRRGQ--QDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPN 128
Query: 99 MCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGG 158
MCTC SGQI+ +CGS+SIQ C++RCMNGG+C+DDHC CQKGYIGT+CGQPVCE+GC NGG
Sbjct: 129 MCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGG 188
Query: 159 RCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG 218
RC+ PNRCAC YGFTGPQCERDYRTGPCFT ++NQMCQGQL+GIVCTKTLCCAT+GRAWG
Sbjct: 189 RCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG 248
Query: 219 HPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHK 278
HPCEMCPAQP PCRRGFIPNIRTGACQDVDECQAIPG+CQGGNCINTVGSFEC+CPAGHK
Sbjct: 249 HPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHK 308
Query: 279 LNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYT 338
+E +QKCEDIDECS IPGICE GEC+NTV SYFC CP G+ TS DG+RCID R G C++
Sbjct: 309 QSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFS 368
Query: 339 ALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLC--SVPMV-I 395
L NGRC+ +LP +TKMQCCC+ GRCW G+ PE CP+R +E++ +LC +PM I
Sbjct: 369 GLVNGRCAQELPGRMTKMQCCCEPGRCW--GIGTIPEACPVRGSEEYRRLCMDGLPMGGI 426
Query: 396 PG----RPE---------------YPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLY 436
PG RP Y P G IP +P GF PG V V
Sbjct: 427 PGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIP--IPGGNGFSPG----VGGAGVG--- 477
Query: 437 PSREPPRVLPVNVT----DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVD 492
+ P + + + D C+ LC NGRCIPT S RCECN G++ D G+CIDVD
Sbjct: 478 AGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVD 537
Query: 493 ECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGS 552
EC NPC G+C+N GSY C+C AG+Q T T+ C DIDEC+QNG +C NGRC+NTDGS
Sbjct: 538 ECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGS 597
Query: 553 FHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK 612
F C+CNAGF +T DGKNC D DEC+ NMCLNGMCINEDGSFKCICKPGF LA +GRYC
Sbjct: 598 FQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCT 657
Query: 613 DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIK 672
D++EC+TPGICMNG C+N++GS+RC+C PGLAVG+DGRVCVDTHMRSTCYGG K+G C++
Sbjct: 658 DVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVR 717
Query: 673 PLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPD 732
P GAVTKSECCCA+ +Y FGEPCQPCPA+NSAE+ LCSSG G+T G DINECALDPD
Sbjct: 718 PFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPD 777
Query: 733 ICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTC 792
IC NGICENLRG+Y+C CNSGYE D++G+NC+DI+EC++N LLCDNG CRNTPGS+ CTC
Sbjct: 778 ICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTC 837
Query: 793 PKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGT 852
P G++++ + +TCEDI+ECES+PC+NG C+N+ GSF CECS S L T ICI+++KGT
Sbjct: 838 PPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGT 897
Query: 853 CWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDID 912
CW + D RCE+NINGATLKS+CC++LGAAWGSPC C++D C +G +RIKG CED++
Sbjct: 898 CWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVN 957
Query: 913 ECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIA 972
ECEVFPGVC NG CVN++GSF C+CP G+TLD TGR+CLDIR+E C+L+++++EC P+
Sbjct: 958 ECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVP 1017
Query: 973 GRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATK-EITNGKPFFKDINE 1031
G+ RMDACCC+VGAAWGTE CEECP T EYE LCPRG GFA + ++ G+PF+KDINE
Sbjct: 1018 GKFRMDACCCAVGAAWGTE-CEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINE 1076
Query: 1032 CKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPG 1091
CK P +CT+GKCRNTIGSFKCRC+SGFALD EERNCTDIDECRISPDLCG G CVNTPG
Sbjct: 1077 CKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPG 1136
Query: 1092 DFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNIS 1151
FEC+C EGYESGFMMMKNCMDIDEC+R+PLLCRGG C NTEGS++C+CP GH+LSP+
Sbjct: 1137 SFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSRE 1196
Query: 1152 ACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETF 1211
C+DINEC LS +LC NG+CVN+IG YQC+CNPGY +TPDR C DIDEC IMNGGC+T
Sbjct: 1197 DCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQ 1256
Query: 1212 CTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 1271
CTNSEGSYECSC G+ALMPD RSC DIDECE+NP+ICDGGQCTNIPGEYRCLCYDGFMA
Sbjct: 1257 CTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMA 1316
Query: 1272 SEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAH 1331
S DMKTC+DVNECDLN NIC+ G CENTKGSFICHC +GYS KKG TGCTD++ECEIGAH
Sbjct: 1317 SMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAH 1376
Query: 1332 NCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLC 1391
NC HA C N GSFKCSC GWIG+GIKC DLDECSNGTH CS +A C NT GSYRC C
Sbjct: 1377 NCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCAC 1436
Query: 1392 KEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECS 1451
EG+TGDGFTC+D+DEC+EN+NLC NGQCLN PG YRCEC+MGF P++D ++C+DIDECS
Sbjct: 1437 SEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS 1496
Query: 1452 LPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYIC 1511
NICVFGTC+NLPG+F C C+ GYELDR+GGNCTD++EC DP C++G CVNTPG Y C
Sbjct: 1497 FQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYEC 1556
Query: 1512 DCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWG 1571
+CPPDF+LNPT VGCVD R GNCYL PRGD G +C+ EIGVGVS++SCCCSLGKAWG
Sbjct: 1557 NCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGD-GSLSCNTEIGVGVSRSSCCCSLGKAWG 1615
Query: 1572 TPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQC 1631
PCE CP VN++EY LCPGGEGFRPNPIT+ILEDIDECQELPGLCQGG CINTFGSFQC
Sbjct: 1616 NPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQC 1675
Query: 1632 RCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
CP GYYL+EDTR+C+D++EC PG+CGPGTCYNT+GNYTCICPP+YMQVNGG+NCMDM
Sbjct: 1676 ECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDM 1735
Query: 1691 RRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGS 1750
R+S CYR+Y + TC+ EL FN+TK+MCCC+YN+G+AWNKPCE CP P T +F T+CG+
Sbjct: 1736 RKSFCYRSY--NGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGN 1793
Query: 1751 QRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDID 1810
PGF DI+TG VDIDEC+EIPG+C NGVCIN +GSFRCECP GF YND LLVCEDID
Sbjct: 1794 I-PGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDID 1852
Query: 1811 ECQNGP-VCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTV 1869
EC NG +CQRNA+CIN+ GSYRC+C G++ + G C DRNEC EIPN+CSHG C+D
Sbjct: 1853 ECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQ 1912
Query: 1870 GSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCI 1929
GS+ C+CH GFK + DQTMC+D++ECER CGNGTC+NT+GS+NC C GF L+HNNDC+
Sbjct: 1913 GSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCL 1972
Query: 1930 DVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTC 1989
D+DEC+S G +CRNG+C N +GSF+C CNEGYE+ PDG+ C+D NEC+ P C+PGTC
Sbjct: 1973 DIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTC 2032
Query: 1990 QNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSS 2049
QNL+GS+RCICPPGY +++E C DI+EC E+P IC G+C+NT G F+CLCP GF LS +
Sbjct: 2033 QNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDN 2092
Query: 2050 GRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCA-LKGEGWGDPCELCPTEPDEAFR 2108
GRRC D R S+C+ FE GKCS PK+ N +K +CCC+ + GEGWGDPCELCP + + AF+
Sbjct: 2093 GRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQ 2152
Query: 2109 QICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSYRCECPFGYIL--AGNECV 2165
+CPYG G + D+ D++EC E P +C +GQCINTDGS+RCECP GY L G CV
Sbjct: 2153 DLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCV 2212
Query: 2166 DTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTY 2225
DTDECS+GNPCGNGTC NVIG FEC C EGFEPGPMM CEDINECAQNPLLCAFRC+NT+
Sbjct: 2213 DTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTF 2272
Query: 2226 GSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPD 2285
GSYEC CP+GY LRED++MCKD DEC EG HDC + M CKNLIGT+MCIC PG RRPD
Sbjct: 2273 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPD 2332
Query: 2286 GEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQ 2345
GEGCVDENEC+TKPGICENGRC+N GSY CECN+GF +S + ECLDNR+G CF EVLQ
Sbjct: 2333 GEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQ 2392
Query: 2346 NMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDE 2405
+CQ+ SS+RN VTKSECCCDGGRGWG CE+CP GT +KK+CPHG G+ T+G DIDE
Sbjct: 2393 TICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDE 2452
Query: 2406 CKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGS 2465
CKV+ ++C NG+C+N GS+ C CK GYT DI+GTSC+DL+EC+Q+PKPCN+ICKNTEGS
Sbjct: 2453 CKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGS 2512
Query: 2466 YQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDN 2525
YQCSCP+GY+LQEDG++CKDLDEC TKQHNCQFLCVNT+GGFTCKCPPGFTQHHT+CIDN
Sbjct: 2513 YQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDN 2572
Query: 2526 NECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNII 2585
NEC S +LCG+KGICQNTPGSF+CECQRGFSLD TG +CEDVDEC+GNHRCQHGCQNI+
Sbjct: 2573 NECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNIL 2632
Query: 2586 GGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGG 2645
GGYRC CPQGY+QHYQWNQCVDENEC + + CG ASC+NTLGSYKC CP+GF ++QFS
Sbjct: 2633 GGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSA 2692
Query: 2646 CQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEM 2705
C D+NEC S++ PC+YGCSNTEGGYLCGCPPGY+R+GQGHCVSGMG +G +
Sbjct: 2693 CHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVD 2752
Query: 2706 DDNSLSPEACYECKINGYPKR-GRKRRSTNETDASNIEDQSETEANVSLASWDVEKTAIF 2764
++N+LSPEACYECKINGY K+ R++RS +E D + +E +SL S D++
Sbjct: 2753 EENALSPEACYECKINGYSKKDSRQKRSIHEPDPTAVE-------QISLESVDMDSPVNM 2805
Query: 2765 AFNISHVSNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKKKPVA 2824
FN+SH+ +K ILEL PA+ L NH RY+I GN+D F+I+Q+ G+SYLH KKK +
Sbjct: 2806 KFNLSHLGSKEHILELRPAIQPLNNHIRYVISQGNDDSVFRIHQRNGLSYLHTAKKKLMP 2865
Query: 2825 GTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH 2871
GTY+L+I+S PLYKKKEL +LE+ + DYL GELG+ L+M++Q+ L+
Sbjct: 2866 GTYTLEITSIPLYKKKELKKLEESNEDDYLLGELGEALRMRLQIQLY 2912
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 3984 bits (10332), Expect = 0.0
Identities = 1698/2855 (59%), Positives = 2123/2855 (74%), Gaps = 105/2855 (3%)
Query: 1 MRRGRLLEIALGFTVLLASYTSHGA-DANLEAGNVKETRASRAKRRGGGGHDALKGPNVC 59
+ RG L + L ++ LL G D LEA R +RRG G L+GPNVC
Sbjct: 8 LARGPLARLLLAWSALLCMAGGQGRWDGALEAAG-----PGRVRRRGSPG--ILQGPNVC 60
Query: 60 GSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 119
GSR++AYCCPGW+T PG +QC+VPICR +CG+GFCS+PN+CTC G +APSCG C
Sbjct: 61 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGC 120
Query: 120 NIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCER 179
++ CMNGG+C CLCQKGY GT CGQP+C+ GC NGGRC+ PNRCAC YGF GPQCER
Sbjct: 121 SVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGFMGPQCER 180
Query: 180 DYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNI 239
DYRTGPCF + + CQ QL+G+VCTK LCCATVGRAWG PCE+CPAQPHPCRRGFIPNI
Sbjct: 181 DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNI 240
Query: 240 RTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGIC 299
TGA C+D+DEC +PG+C
Sbjct: 241 HTGA------------------------------------------CQDVDECQAVPGLC 258
Query: 300 EGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCC 359
+GG C N V S+ C+CP G S C D R G C++ L GRC+ L T+ QCC
Sbjct: 259 QGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCC 318
Query: 360 CDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPM-VIPGRPEYPP-----------PPLG 407
CD GRCW+ G PE+CP R + +F +LC+ + ++PG P P PPLG
Sbjct: 319 CDRGRCWAAGPV--PELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLG 376
Query: 408 PIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVT-DYCQLVRYLCQNGRCI 466
P + P IP L P +N T D C+ LC NGRC+
Sbjct: 377 PAR----LNPHGSDARGIPS-------LGPGNSNIGTATLNQTIDICRHFTNLCLNGRCL 425
Query: 467 PTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRT 526
PTP S RCECN G+ D+RGECIDVDEC +PC G+C+N G+Y C+C G+Q+T TR
Sbjct: 426 PTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQ 485
Query: 527 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM 586
C D+DEC+ +G +C+ GRC+NT+GSF CVCNAGF ++ DGKNC D +EC+ MC+NG+
Sbjct: 486 ACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV 545
Query: 587 CINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVG 646
C+NEDGSF C+CKPGF LA G YC DI+EC+TPGIC+NG C NT+GS+RC+C GLAVG
Sbjct: 546 CLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVG 605
Query: 647 LDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAE 706
DGRVCVDTH+RSTCYG ++G C +P G VTKSECCCA+ ++ FGEPCQ CPA++SAE
Sbjct: 606 TDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAE 665
Query: 707 YQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDI 766
+QALCSSG G+T+ G DINECALDP++C NG+CENLRG+Y+C+CN GYE ++GK+C D+
Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDV 725
Query: 767 NECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPG 826
+EC LNSLLCDNG C+N+PGS+ C+CP GF + D + C+D+DEC SSPC++GVC+N G
Sbjct: 726 DECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAG 785
Query: 827 SFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSP 886
S+ C+C S LDP+ T C+++ KGTCW + + RCE+N+ GA+L+S+CC++LGAAWGSP
Sbjct: 786 SYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSP 845
Query: 887 CTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDAT 946
C C++DP C +G++R+ G C+D++ECE FPGVC NG CVNT GSF+C+CP G+ LDA+
Sbjct: 846 CERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 905
Query: 947 GRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEE 1006
GR+C+D+RLE CFLR++++EC + + G++RMD CCCS+GA WG E CE CP + E+
Sbjct: 906 GRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVE-CEACPDPESLEFAS 964
Query: 1007 LCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEER 1066
LCPRG GFA+++ +G+PF+KD+NECK+ P LCTHG CRNT+GSF C C GFALD++ER
Sbjct: 965 LCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 1067 NCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG 1126
NCTDIDECRISPDLCG+G CVNTPG FEC+C GYESGFM+MKNCMD+DEC RDPLLCRG
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG 1084
Query: 1127 GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGY 1186
G C NT+GSY+C+CPPGH+L+ +AC DI+EC LS LCP+G+CVN+IG +QC+C+ G+
Sbjct: 1085 GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGF 1144
Query: 1187 HSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNP 1246
STPDR CVDI+EC + NGGC+ C N+EGSY CSC G++LMPD R+C D+DECE+NP
Sbjct: 1145 QSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENP 1204
Query: 1247 NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICH 1306
+CD G CTN+PG +RCLCYDGFMA+ DM+TCVDV+ECDLNP+ICL G CENTKGSF+CH
Sbjct: 1205 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCH 1264
Query: 1307 CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDE 1366
C +GY +KG TGC+D++ECE+G HNC HA C N GSF C C PGW+GDG +C DLDE
Sbjct: 1265 CQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDE 1324
Query: 1367 CSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGG 1426
C + H CS DC N GSYRC C++G+ GDGF C D DEC+EN++LC NGQCLNAPGG
Sbjct: 1325 CVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGG 1384
Query: 1427 YRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCT 1486
YRCEC+MGF P+ D +AC+D+DEC+ N+C FG+C NLPG+FRC C GYELDR GGNCT
Sbjct: 1385 YRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCT 1444
Query: 1487 DVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGD 1546
D+NEC DP CI+G C+NTPGSY+C CP DFELNP+ VGCVDTR+GNC+L+ RGD+G
Sbjct: 1445 DINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSG- 1503
Query: 1547 TACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILED 1606
+CS EIGVGV++ASCCCSLG+AWG PCE+CP NT+EY+ LCPGGEGF+PN ITVILED
Sbjct: 1504 ISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILED 1563
Query: 1607 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYN 1665
IDECQELPGLCQGG C+NTFGSFQC CP GY+L+E TR+C+D++EC T GICGPGTCYN
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYN 1623
Query: 1666 TVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNI 1725
T+GNYTC+CP +Y+QVNGGNNCMDMR+S+C+R+Y N TC EL FN+T+KMCCCSYNI
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHY---NGTCQNELAFNVTRKMCCCSYNI 1680
Query: 1726 GRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINM 1785
G+AWN+PCE CP P + ++ LCG+Q PGF+ DI+TG P+DIDEC EIP +C NG+CIN
Sbjct: 1681 GQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQ 1740
Query: 1786 VGSFRCECPVGFFYNDKLLVCEDIDEC-QNGPVCQRNAECINTAGSYRCDCKPGYRFTST 1844
+GSFRCECP GF YN LL CED+DEC CQ+NA+CIN GSYRC C GY+ +
Sbjct: 1741 IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 1845 GQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT 1904
G C RNEC+EIPN+CSHG C+DT GS+ CLCH GF+ + DQT+C+DI+EC+R CGNGT
Sbjct: 1801 GACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT 1860
Query: 1905 CRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEV 1964
C+N IGS+NC C GF+++HN DC+D DEC + G +CR G C+NT GSF C C +G+E+
Sbjct: 1861 CKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFEL 1920
Query: 1965 APDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEIC 2024
DG+ CVD NECL C PGTCQNL+GS+RCICPPG+ +Q++ C DIDEC EEP +C
Sbjct: 1921 TADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLC 1980
Query: 2025 ALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECC 2084
GTC+N+ GSF+CLCP GF LS +G RC D R S+C+ +FE GKCS PK+ N +K CC
Sbjct: 1981 LFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCC 2040
Query: 2085 CALK-GEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQC 2142
C+ + GEGWGDPCELCP E AF+++CP+G G + GPDDS D++EC E P VC +G C
Sbjct: 2041 CSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC 2100
Query: 2143 INTDGSYRCECPFGYIL--AGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGP 2200
+NTDGS+RCECPFGY L G CVDTDECSVG+PCG GTC NVIGGFEC C +GFEPG
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGL 2160
Query: 2201 MMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTE 2260
MMTCEDI+EC+ NPLLCAFRC NT GSY C CP GY LRED MC+D DEC +G+ DC
Sbjct: 2161 MMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHA 2220
Query: 2261 KQMECKNLIGTYMCICGPGYQRRP-DGEGCVDENECQTKPGICENGRCLNTRGSYTCECN 2319
+ MECKNLIGT+ C+C PG + P GEGC D+NEC +P +C NGRC+NT GS+ C+C+
Sbjct: 2221 RGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCD 2280
Query: 2320 DGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICP 2379
+GF SP EC D R+G CF EVLQ MC+ SS+ VT++ECCC GGRGWGP CE+CP
Sbjct: 2281 EGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCP 2340
Query: 2380 FQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITG 2439
GT A++KLCPHG G+ G D+DEC+++ +C +GEC+N GS+ C C+ GYTPD T
Sbjct: 2341 LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATA 2400
Query: 2440 TSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFL 2499
T+C+D++EC+Q PKPC F+CKNT+GS+ CSCP+GY+L+EDGR+CKDLDEC ++QHNCQFL
Sbjct: 2401 TTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFL 2460
Query: 2500 CVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLD 2559
CVNT+G FTC+CPPGFTQHH +C DN+EC++ CG+ G C NTPGSF CEC +GF+L
Sbjct: 2461 CVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLV 2520
Query: 2560 QTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LSAHICG 2618
+G CEDV+EC+G HRCQHGCQN +GGYRCSCPQG+ QH QW QCVDENEC LS CG
Sbjct: 2521 SSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 2619 GASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGY 2678
ASC NTLG ++C+CP+GF ++Q GGCQ+++EC + PCSY C+NT GG+LCGCP GY
Sbjct: 2581 SASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 2679 FRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDA 2738
FR GQGHCVSG+G G + P E+ LS EACYECKING R R RRS +
Sbjct: 2641 FRAGQGHCVSGLGFSPGPQDTPDKEEL----LSSEACYECKINGLSPRDRPRRSAHR--- 2693
Query: 2739 SNIEDQSETEANVSLASWDVEKTAIFAFNISHVSNKVRILELLPALTTLTNHNRYLIESG 2798
+ V+LA+ D E N+SH+ RILEL PAL L RY+I G
Sbjct: 2694 ---------DHQVNLATLDSEALLTLGLNLSHLGRAERILELRPALEGLEGRIRYVIVRG 2744
Query: 2799 NEDGFFKINQKEGISYLHFTKKKPVAGTYSLQISS 2833
NE GFF+++ G+S L +++P GTY L++ S
Sbjct: 2745 NEQGFFRMHHLRGVSSLQLGRRRPGPGTYRLEVVS 2779
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 547 bits (1409), Expect = e-155
Identities = 372/1114 (33%), Positives = 488/1114 (43%), Gaps = 153/1114 (13%)
Query: 914 CEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAG 973
C+ P VC G C++ + C C SG L G C+D+ +EC
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDV-----------DEC------ 524
Query: 974 RHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECK 1033
R C+ G CE P C GPGF D++EC
Sbjct: 525 --RRVPPPCAPG------RCENSPGSFR------CVCGPGFRAGPRAAE---CLDVDECH 567
Query: 1034 MIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDF 1093
+P C G+C NT GSF C C +G+ +C D+DEC SP LCGRG C N PG F
Sbjct: 568 RVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSF 627
Query: 1094 ECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISAC 1153
C C G+ D+DEC ++P C G C NT GS+ C CP G + + C
Sbjct: 628 RCVCPAGFRGSACEE----DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 683
Query: 1154 IDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCT 1213
D++EC S C GRC N G +QC C G+ C D+DEC C
Sbjct: 684 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV 743
Query: 1214 NSEGSYEC-SCQPGFALMPDQRSCTDIDECEDNPNICDG-GQCTNIPGEYRCLCYDGFMA 1271
NS GS++C +C G L + CTD+DEC C G CTN G +RC C G+ A
Sbjct: 744 NSPGSFQCRTCPSGHHL--HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 801
Query: 1272 SEDMK-TCVDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIG 1329
C DVNEC L + C G C NT GSF C C GY C D++EC
Sbjct: 802 PSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-- 858
Query: 1330 AHNCGKHAVCTNTAGSFKCSCSPGWIG--DGIKCTDLDEC-SNGTHMCSQHADCKNTMGS 1386
+ + +CTNT GSF+C C PG D C D+DEC G +C C+N+ GS
Sbjct: 859 EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR-CENSPGS 917
Query: 1387 YRCL--CKEGY-TGDGFTCTDLDECSE-NLNLCGNGQCLNAPGGYRCE--CDMGFVPSAD 1440
YRC+ C GY G TC D+DEC E +CG +C N PG YRC CD G+ P+
Sbjct: 918 YRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPG 977
Query: 1441 GKACEDIDECSLPNIC-VFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCI 1498
G C+D+DEC + C C NLPG F+C C+ GYE R G +C DVNEC C
Sbjct: 978 G-GCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCG 1036
Query: 1499 SGNCVNTPGSYICDCP--PDFELNPTRVGCVDTRSG-------------NCYLDIRP--- 1540
+ C N GS++C CP P+ E +P CV R+ + L RP
Sbjct: 1037 AALCENVEGSFLCVCPNSPE-EFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPP 1095
Query: 1541 ----------RGDNG--------DTA----CSNEIGVGVSKASCCCSLGKAWGTPC--EM 1576
+G G DTA C N + V+ CCC++G+ WG+ C +
Sbjct: 1096 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ 1155
Query: 1577 CPAVNTSEYKILCPGGEGF-RPNPITVILEDIDECQELPG-LCQGGKCINTFGSFQCRCP 1634
CP T+EY+ LCP G G+ P+ + D+DECQ +C+ G C+NT + C C
Sbjct: 1156 CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCS 1215
Query: 1635 TGYYLNEDTRVCDDVNEC--ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNC----- 1687
GYY + C D +EC E P C G C NTVG+Y C C P + C
Sbjct: 1216 NGYYYHTQRLECIDNDECADEEPA-CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNES 1274
Query: 1688 --MDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFA 1745
+D +C++ AD L T CCC Y G AW C CP +D+F
Sbjct: 1275 QSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLY--GEAWGMDCALCPAQDSDDFE 1332
Query: 1746 TLCGSQRP---------GFVIDI---------YTGLPVDIDECREIPGVCENGVCINMVG 1787
LC RP GF + Y GLP E P + +
Sbjct: 1333 ALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYG-PELYPPPALPYDPYPPPPGP 1391
Query: 1788 SFRCECPVGF-------FYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKP--- 1837
R E P G F +D E GP + +T S+ +P
Sbjct: 1392 FARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEG 1451
Query: 1838 GYRFTSTGQCNDRNECQE--IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC 1895
G S + + E +E I + C++G+C+ F C C G++ + + C+DINEC
Sbjct: 1452 GSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINEC 1511
Query: 1896 ER-----DACGNGTCRNTIGSFNCRCNHGFILSH 1924
+ C N C NT GSF C C GF +H
Sbjct: 1512 DEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1545
Score = 490 bits (1262), Expect = e-138
Identities = 343/1175 (29%), Positives = 483/1175 (41%), Gaps = 263/1175 (22%)
Query: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGT-PCEMCPAVNTSEYKILCP 1590
G C+ ++R G+ C++ + ++ CC G AWG C++C + ++ P
Sbjct: 220 GYCFRELR----GGE--CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP 273
Query: 1591 GGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVN 1650
G CPTG+ + C+DV+
Sbjct: 274 DGP---------------------------------------CPTGFERVNGS--CEDVD 292
Query: 1651 ECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMR-----RSLCYRNYYADNQT 1705
EC T G C G C NT G YTC+CP ++ + ++C+ + C+R +
Sbjct: 293 ECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFR--VLRDGG 350
Query: 1706 CDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDI----YT 1761
C +L N+TK++CCCS +G+AW + C+ CP ++ F +C + PG+ Y
Sbjct: 351 CSLPILRNITKQICCCS-RVGKAWGRGCQLCPPFGSEGFREICPAG-PGYHYSASDLRYN 408
Query: 1762 GLP-------VDIDECREIPGVCENGVCINMVGSFRCEC---------PVGFFYNDKLLV 1805
P V + + R +P + + R E P +
Sbjct: 409 TRPLGQEPPRVSLSQPRTLPATSRPSA--GFLPTHRLEPRPEPRPDPRPGPELPLPSIPA 466
Query: 1806 CEDIDECQNGP---VCQRNAE------CINTAGSYRCDCKPGYRFTSTG-QCNDRNECQE 1855
+ ++GP +CQRN + CI+ Y C C G+R + G +C D +EC+
Sbjct: 467 WTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRR 526
Query: 1856 IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER--DACGNGTCRNTIGSFN 1913
+P C+ G+C ++ GSF C+C GF+ CLD++EC R C G C NT GSF
Sbjct: 527 VPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFL 586
Query: 1914 CRCNHGFILS-HNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCV 1972
C C G+ + H C DVDEC G LC G C N GSF+C C G+ G C
Sbjct: 587 CVCPAGYQAAPHGASCQDVDECTQSPG-LCGRGACKNLPGSFRCVCPAGFR----GSACE 641
Query: 1973 -DINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTC 2029
D++EC EP C PG C N GS+ C CP G+ + C+D+DEC P C G C
Sbjct: 642 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRC 701
Query: 2030 SNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC----------SSPKSRNHS 2079
NTEGSF+C+CP GF +++G C+D+ + G +C + P +
Sbjct: 702 ENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH 761
Query: 2080 KQECCCALKGEGWGDPCEL---CPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDV 2136
+ C + PC C T + +FR C G G D++EC E D
Sbjct: 762 RGRCTDVDECSSGAPPCGPHGHC-TNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDF 820
Query: 2137 C-KHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVIGGFECTCE 2193
C HG+C+NTDGS+ C C GY G C+D DECS + C +G C N G FEC C
Sbjct: 821 CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICP 880
Query: 2194 EGFEPGP-MMTCEDINECAQN-PLLCAF-RCVNTYGSYEC--KCPVGYVLREDRRMCKDE 2248
G GP + +C D++EC + P LC RC N+ GSY C C GY + C D
Sbjct: 881 PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDV 939
Query: 2249 DECEE---------------GKHDCTEK---------------------------QMECK 2266
DEC+E G + CT C+
Sbjct: 940 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQ 999
Query: 2267 NLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCEC-NDGFTAS 2325
NL G++ C+C GY+ DG CVD NEC+T G+C C N GS+ C C N
Sbjct: 1000 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD 1059
Query: 2326 PNQDECLDNREGYCFTEVLQNMCQ-------------------------IGSSNRN---- 2356
P C+ R Q +GS R
Sbjct: 1060 PMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFD 1119
Query: 2357 -------------PVTKSECCCDGGRGWGPHCEI--CPFQGTVAFKKLCPHGRGFMTNGA 2401
VT ECCC G GWG C I CP T ++ LCPHGRG++
Sbjct: 1120 TAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG 1179
Query: 2402 D------IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC 2455
D +DEC++ D +CK+G
Sbjct: 1180 DLSLRRDVDECQLFRDQ---------------VCKSG----------------------- 1201
Query: 2456 NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPG 2514
+C NT Y C C GY C D DECA ++ C+ CVNT+G + C C P
Sbjct: 1202 --VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1259
Query: 2515 FTQHHTS--CIDNNECTSDINLCGSKGICQNTPGS 2547
+ C+ N + D NL G+C G+
Sbjct: 1260 LVLDGSQRRCVSNESQSLDDNL----GVCWQEVGA 1290
Score = 478 bits (1230), Expect = e-134
Identities = 412/1505 (27%), Positives = 557/1505 (37%), Gaps = 299/1505 (19%)
Query: 958 CFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATK 1017
CF EC P+ G + CC G AWG +C+ C R P GP
Sbjct: 222 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP----- 276
Query: 1018 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 1077
C +GF + +C D+DEC
Sbjct: 277 -------------------------------------CPTGF--ERVNGSCEDVDECATG 297
Query: 1078 PDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG-GVCHNTEGSY 1136
C G+C NT G + C C + GF++ + C ++ G C
Sbjct: 298 -GRCQHGECANTRGGYTCVCPD----GFLLDSSR---SSCISQHVISEAKGPCFRVLRDG 349
Query: 1137 RCECPPGHQLSPNISACIDINEC-ELSAHLCPNGRCVNLIGKYQCACNPGY-HSTPDRLF 1194
C P ++ I C + + LCP + C PGY +S D +
Sbjct: 350 GCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGF--REICPAGPGYHYSASDLRY 407
Query: 1195 C----------VDIDECSIMN-------GGCETFCTNSEGSYECSCQPGFAL-MPDQRSC 1236
V + + + G T +PG L +P +
Sbjct: 408 NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW 467
Query: 1237 T--DIDE-------CEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLN 1287
T +I E C+ NP +C G+C + P Y C C GF S C+DV+EC
Sbjct: 468 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 527
Query: 1288 PNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFK 1347
P C G CEN+ GSF C C G+ C D++EC C C NT GSF
Sbjct: 528 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFL 586
Query: 1348 CSCSPGWIG--DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDL 1405
C C G+ G C D+DEC+ +C + A CKN GS+RC+C G+ G D+
Sbjct: 587 CVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE-EDV 644
Query: 1406 DECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNL 1464
DEC++ CG G+C N G + C C GF G C+D+DEC+ P C +G C N
Sbjct: 645 DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT 704
Query: 1465 PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYIC-DCPPDFELNPTR 1523
G F+C C +G++ + +G C DV+EC + C CVN+PGS+ C CP L+ R
Sbjct: 705 EGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR 764
Query: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS 1583
VD C P G +G C+N G C C+ G
Sbjct: 765 CTDVD----ECSSGAPPCGPHGH--CTNTEG----SFRCSCAPG---------------- 798
Query: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDT 1643
Y+ P G RP P D++EC E G+C+NT GSF C C GY
Sbjct: 799 -YR--APSG---RPGPCA----DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRG 848
Query: 1644 RVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADN 1703
C DV+EC +C G C NT G++ CICPP + +C+D+ +
Sbjct: 849 ASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 908
Query: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGL 1763
Q C+ + C Y+ G P + D
Sbjct: 909 QRCENSPGSYRCVRDCDPGYHAG----------PEGTCD--------------------- 937
Query: 1764 PVDIDECREI-PGVCENGVCINMVGSFRCE--CPVGFFYNDKLLVCEDIDECQNGPVCQR 1820
D+DEC+E P +C C N GS+RC C G+ C+D+DEC+N C
Sbjct: 938 --DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGA 994
Query: 1821 NAECINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTG 1879
+A C N GS++C C GY G+ C D NEC+ + +C C + GSF C+C
Sbjct: 995 HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNS 1054
Query: 1880 FKTNDDQTMCLDINECERDACGNGTC------------------------------RNTI 1909
+ D T C GT + +
Sbjct: 1055 PEEFDPMT-----GRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1109
Query: 1910 GSFNCRCNHGF--------ILSHNNDCIDVDECA----SGNGNLCRNGQCINT-VGSFQC 1956
GS C IL+ N + EC G G+ CR QC T +Q
Sbjct: 1110 GSGRRECYFDTAAPDACDNILARN---VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQS 1166
Query: 1957 QCNEGYE-VAPDGRTCV--DINEC-LLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK-- 2010
C G +AP G + D++EC L + C G C N Y C C GY ++
Sbjct: 1167 LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1226
Query: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ-------DLRMSYCYA 2063
C D DEC +E C G C NT GS+ C C L S RRC D + C+
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1286
Query: 2064 KFEGGK-CSSPK-SRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC---------- 2111
+ CS P+ R + ECCC L GE WG C LCP + + F +C
Sbjct: 1287 EVGADLVCSHPRLDRQATYTECCC-LYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSP 1345
Query: 2112 --------PYGSGIIVGPDDSAVDMD-ECKEPDVCKHGQCINTDGSY-RCECPFGYILAG 2161
PY G +GP + E P + G + R E P+G
Sbjct: 1346 PRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFD 1405
Query: 2162 NECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMM--------TCEDINECAQN 2213
+ D G P G E PGP T E +
Sbjct: 1406 MPDFEDD----GGPYGES-------------EAPAPPGPGTRWPYRSRDTRRSFPEPEEP 1448
Query: 2214 PLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYM 2273
P GSY Y E C D C G+ C + +
Sbjct: 1449 P---------EGGSYAGSLAEPYEELEAEE-CGILDGCTNGR---------CVRVPEGFT 1489
Query: 2274 CICGPGYQRRPDGEGCVDENEC---QTKPGICENGRCLNTRGSYTCECNDGFTASPNQDE 2330
C C GY+ CVD NEC + +C N RCLNT GS+ C C GF +
Sbjct: 1490 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHH 1549
Query: 2331 CLDNR 2335
C R
Sbjct: 1550 CAPAR 1554
Score = 463 bits (1192), Expect = e-130
Identities = 346/1178 (29%), Positives = 491/1178 (41%), Gaps = 215/1178 (18%)
Query: 531 IDEC-LQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCIN 589
+ +C L + R+ N+ R DG C GF R +CED+DEC+ C +G C N
Sbjct: 254 VHDCQLCSERLGNSERVSAPDGP----CPTGFE--RVNGSCEDVDECATGGRCQHGECAN 307
Query: 590 EDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCECFPGLAVGLD 648
G + C+C GF L S C + E G C V DG C + +
Sbjct: 308 TRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFR---VLRDGG----CSLPILRNIT 360
Query: 649 GRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFG-------------EP 695
++C + + + RG + P FG+ E C A Y + EP
Sbjct: 361 KQICCCSRVGKA----WGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP 416
Query: 696 CQ---------PCPAQNSAEYQAL-------------------------CSSGPGMTSAG 721
+ P ++ SA + +GP + +G
Sbjct: 417 PRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESG 476
Query: 722 SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQC 781
C +P +C G C + Y C C+SG+ + G C+D++EC C G+C
Sbjct: 477 PSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRC 536
Query: 782 RNTPGSFVCTCPKGFIYKPDLKTCEDIDECE--SSPCINGVCKNSPGSFICECSSESTLD 839
N+PGSF C C GF P C D+DEC PC G C+N+PGSF+C C +
Sbjct: 537 ENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAA 596
Query: 840 PTKTICIETIK-----GTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPC-----TL 889
P C + + G C + G C+ N+ G+ +C G GS C
Sbjct: 597 PHGASCQDVDECTQSPGLCGR----GACK-NLPGS---FRCVCPAGFR-GSACEEDVDEC 647
Query: 890 CQVDPICGKG-----------------YSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGS 932
Q P CG G SR G C+D+DEC P C G C NT GS
Sbjct: 648 AQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGS 707
Query: 933 FKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEE 992
F+C CP G + G C D+ L +EC + G+ +
Sbjct: 708 FQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV-----------------NSPGSFQ 750
Query: 993 CEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKM-IPSLCTHGKCRNTIGSF 1051
C CP + + G+ D++EC P HG C NT GSF
Sbjct: 751 CRTCP-----------------SGHHLHRGR--CTDVDECSSGAPPCGPHGHCTNTEGSF 791
Query: 1052 KCRCDSGFALDSEERN-CTDIDECRISPDLC-GRGQCVNTPGDFECKCDEGYESGFMMMK 1109
+C C G+ S C D++EC + D C G+C+NT G F C C GY G
Sbjct: 792 RCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPG-PRGA 849
Query: 1110 NCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINEC-ELSAHLCPN 1168
+C+D+DEC + LC+ G+C NT+GS+ C CPPGH+ P++++C+D++EC E LC +
Sbjct: 850 SCLDVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 908
Query: 1169 GRCVNLIGKYQCA--CNPGYHSTPDRLFCVDIDECSIMNG---GCETFCTNSEGSYEC-- 1221
RC N G Y+C C+PGYH+ P+ C D+DEC G + C N+ GSY C
Sbjct: 909 QRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQR-CENTPGSYRCTP 966
Query: 1222 SCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDV 1281
+C PG+ P C D+DEC + C N+PG ++CLC G+ + D + CVDV
Sbjct: 967 ACDPGYQPTPG-GGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 1025
Query: 1282 NECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTN 1341
NEC+ +C + CEN +GSF+C C TG G + +
Sbjct: 1026 NECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPAS 1085
Query: 1342 TAGSFKCSCSP----------GWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGS----Y 1387
+ P G +G G + EC T + C N +
Sbjct: 1086 PVLPARPPPPPLPRRPSTPRQGPVGSGRR-----ECYFDT---AAPDACDNILARNVTWQ 1137
Query: 1388 RCLCKEGYTGDGFTCTDLDEC-----SENLNLCGNGQCLNAPGGYRCECDMGFVPSADGK 1442
C C G G G C + +C +E +LC +G+ GY PS D
Sbjct: 1138 ECCCTVG-EGWGSGCR-IQQCPGTETAEYQSLCPHGR------GY-------LAPSGDLS 1182
Query: 1443 ACEDIDECSL--PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCIS 1499
D+DEC L +C G C N + C C GY C D +EC D C
Sbjct: 1183 LRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG 1242
Query: 1500 GNCVNTPGSYICDCPPDFELNPTRVGCVDTRS-------GNCYLDIRPRGDNGDTACSN- 1551
G CVNT GSY C C P L+ ++ CV S G C+ ++ D CS+
Sbjct: 1243 GRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEV-----GADLVCSHP 1297
Query: 1552 EIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILC 1589
+ + CCC G+AWG C +CPA ++ +++ LC
Sbjct: 1298 RLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC 1335
Score = 451 bits (1159), Expect = e-126
Identities = 329/1091 (30%), Positives = 440/1091 (40%), Gaps = 229/1091 (20%)
Query: 184 GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG-HPCEMCPAQPHPCRRGFIPNIRTG 242
G CF + C L G+ T+ +CC G AWG H C++C + R P
Sbjct: 220 GYCFRELRGGECASPLPGLR-TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP----- 273
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
+ CP G + V+ CED+DEC+T G C+ G
Sbjct: 274 ---------------------------DGPCPTGFE--RVNGSCEDVDECAT-GGRCQHG 303
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVR-----PGYCYTALTNGRCSNQLPQSITKMQ 357
EC NT Y C CP GF + CI G C+ L +G CS + ++ITK
Sbjct: 304 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQI 363
Query: 358 CCCD-AGRCWSPGVTVAPEMCPIRATEDFNKLC--------------------------- 389
CCC G+ W G ++CP +E F ++C
Sbjct: 364 CCCSRVGKAWGRGC----QLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRV 419
Query: 390 --SVPMVIP--GRPE---YPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPP 442
S P +P RP P L P P P P PGP++P+P P + E P
Sbjct: 420 SLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDP---RPGPELPLPSIPA---WTGPEIP 473
Query: 443 RVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRG-ECIDVDECEK--NPC 499
P + CQ +C GRCI P C C+ GF+L +G CIDVDEC + PC
Sbjct: 474 ESGP--SSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC 531
Query: 500 AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNA 559
A G C N+ GS+ C C G+++ EC D+DEC + C+ GRC NT GSF CVC A
Sbjct: 532 APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPA 591
Query: 560 GFHVTRDGKNCEDMDECSI------RNMCLN----------------------------- 584
G+ G +C+D+DEC+ R C N
Sbjct: 592 GYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEP 651
Query: 585 -----GMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCE 638
G C N GSF C C GF+ G C+D++EC +P C GRC NT+GS++C
Sbjct: 652 PPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCV 711
Query: 639 CFPGLAVGLDGRVCVD-----THMR---STCYGGYKRGQCIKPLFGAVTKSECCCASTEY 690
C G G C D H+ C QC G C E
Sbjct: 712 CPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDEC 771
Query: 691 AFG-EPCQPCPAQNSAEYQALCSSGPGMTSAG------SDINECALDPDIC-PNGICENL 742
+ G PC P + E CS PG + +D+NEC L+ D C P+G C N
Sbjct: 772 SSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNT 830
Query: 743 RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDL 802
G++ C C GY G +C+D++EC LC +G C NT GSF C CP G PDL
Sbjct: 831 DGSFACTCAPGYRPGPRGASCLDVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDL 889
Query: 803 KTCEDIDEC-ESSPCINGV--CKNSPGSFIC--ECSSESTLDPTKTICIETIKGTCWQTV 857
+C D+DEC E P + G C+NSPGS+ C +C P T C + + +
Sbjct: 890 ASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPE 948
Query: 858 IDG--RCEININGATLKSQCCSSLGAAWGSPC---------------TLCQVDP-----I 895
I G RCE C G C +CQ P +
Sbjct: 949 ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1008
Query: 896 CGKGYSRIK-GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCP-SGMTLDATGRICLDI 953
C +GY + G C D++ECE GVC LC N GSF C CP S D C+
Sbjct: 1009 CDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP 1068
Query: 954 RL--------------------------------------------ETCFLRYEDEECTL 969
R E F + C
Sbjct: 1069 RTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDN 1128
Query: 970 PIAGRHRMDACCCSVGAAWGTE-ECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKD 1028
+A CCC+VG WG+ ++CP T EY+ LCP G G+ + +D
Sbjct: 1129 ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAP--SGDLSLRRD 1186
Query: 1029 INECKMI-PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
++EC++ +C G C NT + C C +G+ ++ C D DEC C G+CV
Sbjct: 1187 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1246
Query: 1088 NTPGDFECKCD 1098
NT G + C C+
Sbjct: 1247 NTVGSYHCTCE 1257
Score = 424 bits (1090), Expect = e-118
Identities = 309/980 (31%), Positives = 406/980 (41%), Gaps = 172/980 (17%)
Query: 1453 PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCISGNCVNTPGSYIC 1511
P +C G C + P + C C+ G+ L G C DV+EC P C G C N+PGS+ C
Sbjct: 486 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRC 545
Query: 1512 DCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWG 1571
C P F P C+D C+ P C LG+
Sbjct: 546 VCGPGFRAGPRAAECLDV--DECHRVPPP-----------------------CDLGRCEN 580
Query: 1572 TPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQC 1631
TP + +CP G ++ P +D+DEC + PGLC G C N GSF+C
Sbjct: 581 TP---------GSFLCVCPAG--YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRC 629
Query: 1632 RCPTGYYLNEDTRVCDDVNEC-ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
CP G+ + +DV+EC + P CGPG C NT G++ C CP + G C D+
Sbjct: 630 VCPAGF---RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDV 686
Query: 1691 RRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCE-QCPIPSTDEFATLCG 1749
C R+ C+Y GR N QC P
Sbjct: 687 DE--CARSPPP-------------------CTY--GRCENTEGSFQCVCPM--------- 714
Query: 1750 SQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCE-CPVGFFYNDKLLVCED 1808
GF + D+DEC E C C+N GSF+C CP G + C D
Sbjct: 715 ----GFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR--CTD 767
Query: 1809 IDECQNG-PVCQRNAECINTAGSYRCDCKPGYRFTS--TGQCNDRNECQEIPNICSHGQC 1865
+DEC +G P C + C NT GS+RC C PGYR S G C D NEC E HG+C
Sbjct: 768 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGEC 827
Query: 1866 IDTVGSFYCLCHTGFKTNDDQTMCLDINEC-ERDACGNGTCRNTIGSFNCRCNHGFILSH 1924
++T GSF C C G++ CLD++EC E D C +G C NT GSF C C G
Sbjct: 828 LNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 887
Query: 1925 N-NDCIDVDECASGNGNLCRNGQCINTVGSFQC--QCNEGYEVAPDGRTCVDINECL-LE 1980
+ C+DVDEC LC + +C N+ GS++C C+ GY P+G TC D++EC
Sbjct: 888 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYG 946
Query: 1981 PRKCAPGTCQNLDGSYRCI--CPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFK 2037
P C C+N GSYRC C PGY C+D+DEC A C N GSF+
Sbjct: 947 PEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1006
Query: 2038 CLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCE 2097
CLC +G+ + GR C D+ G C + N C
Sbjct: 1007 CLCDQGYEGARDGRHCVDVNECETLQ----GVCGAALCENVEGSFLC------------- 1049
Query: 2098 LCPTEPDE----AFRQICPYGS-GIIVGPDDSAVDMDEC----------KEPDVCKHGQC 2142
+CP P+E R + P S G G A + P + G
Sbjct: 1050 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1109
Query: 2143 INTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCE--EGFEPGP 2200
GS R EC F + + + C N +NV EC C EG+ G
Sbjct: 1110 ----GSGRRECYF-------------DTAAPDACDNILARNVTWQ-ECCCTVGEGWGSG- 1150
Query: 2201 MMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVG--YVLRE-DRRMCKDEDECEEGKHD 2257
C I +C Y+ CP G Y+ D + +D DEC+ + D
Sbjct: 1151 ---CR-IQQCPGTET----------AEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFR-D 1195
Query: 2258 CTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCE 2317
K C N Y C C GY C+D +EC + CE GRC+NT GSY C
Sbjct: 1196 QVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCT 1255
Query: 2318 CNDGFTASPNQDEC-------LDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRG 2370
C +Q C LD+ G C+ EV ++ T +ECCC G
Sbjct: 1256 CEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEA 1315
Query: 2371 WGPHCEICPFQGTVAFKKLC 2390
WG C +CP Q + F+ LC
Sbjct: 1316 WGMDCALCPAQDSDDFEALC 1335
Score = 379 bits (973), Expect = e-104
Identities = 274/839 (32%), Positives = 357/839 (42%), Gaps = 140/839 (16%)
Query: 1938 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYR 1997
N +C G+CI+ + C C+ G+ ++P G C+D++EC P CAPG C+N GS+R
Sbjct: 485 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 544
Query: 1998 CICPPGYSL--QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQD 2055
C+C PG+ + +C D+DEC P C LG C NT GSF C+CP G+ + G CQD
Sbjct: 545 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 604
Query: 2056 LRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGS 2115
+ +C+ L G G C P +FR +CP G
Sbjct: 605 V-----------DECTQSPG-----------LCGRG------ACKNLPG-SFRCVCPAG- 634
Query: 2116 GIIVGPDDSAVDMDEC-KEPDVCKHGQCINTDGSYRCECPFGYILAGN--ECVDTDECSV 2172
D+DEC +EP C G+C NT GS+ C CP G+ G C D DEC+
Sbjct: 635 ---FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECAR 691
Query: 2173 GNP-CGNGTCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQNPLLCAFR-CVNTYGSYE 2229
P C G C+N G F+C C GF+P + CED++EC +N L C + CVN+ GS++
Sbjct: 692 SPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQ 750
Query: 2230 CK-CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG 2288
C+ CP G+ L R C D DEC G C C N G++ C C PGY R P G
Sbjct: 751 CRTCPSGHHLHRGR--CTDVDECSSGAPPCGPHG-HCTNTEGSFRCSCAPGY-RAPSGRP 806
Query: 2289 --CVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQN 2346
C D NEC +G CLNT GS+ C C G+ P CLD E C E +
Sbjct: 807 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE--CSEE---D 861
Query: 2347 MCQIGSSNRNPVTKSECCCDGGRGWGP----------------------HCEICPFQGTV 2384
+CQ G N EC C G GP CE P G+
Sbjct: 862 LCQSGICT-NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP--GSY 918
Query: 2385 AFKKLCPHGRGFMTNGA--DIDECKVIH-DVCRNGECVNDRGSYHCI--CKTGYTPDITG 2439
+ C G G D+DEC+ ++C C N GSY C C GY P G
Sbjct: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PG 977
Query: 2440 TSCVDLNEC-NQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC-Q 2497
C D++EC N++ + +C+N GS+QC C +GY DGR C D++EC T Q C
Sbjct: 978 GGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGA 1037
Query: 2498 FLCVNTIGGFTCKC---PPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQ- 2553
LC N G F C C P F C+ TS GS+ P S +
Sbjct: 1038 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR--TSAGTFPGSQ---PQAPASPVLPARP 1092
Query: 2554 ------RGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGG-------------------- 2587
R S + G EC + C NI+
Sbjct: 1093 PPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR 1152
Query: 2588 -----------YRCSCP--QGYLQ---HYQWNQCVDENECLSAHICGGASCHNTLGSYKC 2631
Y+ CP +GYL + VDE + +C C NT Y C
Sbjct: 1153 IQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC 1212
Query: 2632 MCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGC-PPGYFRIGQGHCVS 2688
C G+ Y C D +EC + C G C NT G Y C C PP Q CVS
Sbjct: 1213 YCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1271
Score = 367 bits (943), Expect = e-101
Identities = 274/930 (29%), Positives = 378/930 (40%), Gaps = 154/930 (16%)
Query: 172 FTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPC 231
+TGP+ +GP S+ MCQ VC C + R G+ C C
Sbjct: 467 WTGPEIPE---SGP-----SSGMCQRNPQ--VCGPGRC---ISRPSGYTCA--------C 505
Query: 232 RRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDE 291
GF + + C DVDEC+ +P C G C N+ GSF C C G + + +C D+DE
Sbjct: 506 DSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE 565
Query: 292 CSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV-----RPGYCYTALTNGRCS 346
C +P C+ G C NT S+ C CP G+ +P G C DV PG C G C
Sbjct: 566 CHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLC----GRGACK 621
Query: 347 NQLPQSITKMQCCCDAG----RCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPG--RPE 400
N LP S +C C AG C A E P N S P R
Sbjct: 622 N-LPGS---FRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 677
Query: 401 YPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYL- 459
P P + PP G + + + P P D + +L
Sbjct: 678 GPGAPCQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLA 736
Query: 460 CQNGRCIPTPGSCRCE-CNKGFQLDLRGECIDVDECEKN--PCA-GGECINNQGSYTCQC 515
C C+ +PGS +C C G L RG C DVDEC PC G C N +GS+ C C
Sbjct: 737 CPGQECVNSPGSFQCRTCPSGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 795
Query: 516 RAGYQSTLTRT-ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMD 574
GY++ R C D++ECL+ +G C+NTDGSF C C G+ G +C D+D
Sbjct: 796 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 855
Query: 575 ECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET--PGICMNGRCVNTD 632
ECS ++C +G+C N DGSF+CIC PG + D C D++EC P +C + RC N+
Sbjct: 856 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 915
Query: 633 GSYRC--ECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEY 690
GSYRC +C PG G +G C D EC E
Sbjct: 916 GSYRCVRDCDPGYHAGPEG-TCDDV-------------------------DECQEYGPEI 949
Query: 691 AFGEPCQPCPAQNSAEYQALCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKC 748
+ C+ P S C G T G D++EC + +C+NL G+++C
Sbjct: 950 CGAQRCENTP--GSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC 1007
Query: 749 ICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDI 808
+C+ GYE G++CVD+NEC +C C N GSF+C CP + D T +
Sbjct: 1008 LCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNS-PEEFDPMTGRCV 1066
Query: 809 DECESSPCINGVCKNSPGSFICECSSESTLDPTKTIC-----IETIKGTCW-QTVIDGRC 862
S+ G +P S + P + + + + C+ T C
Sbjct: 1067 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDAC 1126
Query: 863 EININGATLKSQCCSSLGAAWGSPCTL--------------------------------- 889
+ + +CC ++G WGS C +
Sbjct: 1127 DNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRD 1186
Query: 890 ---CQV--DPICGKG-----------------YSRIKGTQCEDIDECEVFPGVCKNGLCV 927
CQ+ D +C G Y + +C D DEC C+ G CV
Sbjct: 1187 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1246
Query: 928 NTRGSFKCQCPSGMTLDATGRIC-------LDIRLETCFLRY-EDEECTLPIAGRH-RMD 978
NT GS+ C C + LD + R C LD L C+ D C+ P R
Sbjct: 1247 NTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYT 1306
Query: 979 ACCCSVGAAWGTEECEECPMRNTPEYEELC 1008
CCC G AWG +C CP +++ ++E LC
Sbjct: 1307 ECCCLYGEAWGM-DCALCPAQDSDDFEALC 1335
Score = 351 bits (901), Expect = 5e-96
Identities = 272/815 (33%), Positives = 362/815 (44%), Gaps = 85/815 (10%)
Query: 1925 NNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC 1984
N C DVDECA+G C++G+C NT G + C C +G+ + +C+ + E
Sbjct: 285 NGSCEDVDECATGGR--CQHGECANTRGGYTCVCPDGFLLDSSRSSCIS-QHVISE---- 337
Query: 1985 APGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2044
A G C + C P ++ + C C L +EG F+ +CP G
Sbjct: 338 AKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG-FREICPAGP 396
Query: 2045 SLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPT--- 2101
S DLR + E + S + R + G+ L P
Sbjct: 397 GYHYSA---SDLRYNTRPLGQEPPRVSLSQPRTLP----ATSRPSAGFLPTHRLEPRPEP 449
Query: 2102 EPDEAFRQICPYGS-GIIVGPD--DSAVDMDEC-KEPDVCKHGQCINTDGSYRCECPFGY 2157
PD P S GP+ +S C + P VC G+CI+ Y C C G+
Sbjct: 450 RPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGF 509
Query: 2158 ILA--GNECVDTDECS-VGNPCGNGTCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQN 2213
L+ G C+D DEC V PC G C+N G F C C GF GP C D++EC +
Sbjct: 510 RLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 569
Query: 2214 PLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTY 2272
P C RC NT GS+ C CP GY C+D DEC + C CKNL G++
Sbjct: 570 PPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA--CKNLPGSF 627
Query: 2273 MCICGPGYQRRPDGEGCVDE-NECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDEC 2331
C+C G++ G C ++ +EC +P C GRC NT GS+ C C GF + C
Sbjct: 628 RCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 683
Query: 2332 LDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGG---RGWGPHCE---------ICP 2379
D E C C G N +C C G G CE CP
Sbjct: 684 QDVDE--CARS--PPPCTYGRCE-NTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP 738
Query: 2380 FQGTV----AFK-KLCPHG----RGFMTNGADIDECKVIHDVCR-NGECVNDRGSYHCIC 2429
Q V +F+ + CP G RG T D+DEC C +G C N GS+ C C
Sbjct: 739 GQECVNSPGSFQCRTCPSGHHLHRGRCT---DVDECSSGAPPCGPHGHCTNTEGSFRCSC 795
Query: 2430 KTGY-TPDITGTSCVDLNECNQAPKPC--NFICKNTEGSYQCSCPKGYILQEDGRSCKDL 2486
GY P C D+NEC + C + C NT+GS+ C+C GY G SC D+
Sbjct: 796 APGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDV 854
Query: 2487 DECATKQHNCQFLCVNTIGGFTCKCPPGFTQHH--TSCIDNNECTS-DINLCGSKGICQN 2543
DEC+ + +C NT G F C CPPG SC+D +EC LCGS+ C+N
Sbjct: 855 DECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR-CEN 913
Query: 2544 TPGSFTC--ECQRGFSLDQTGSSCEDVDECE--GNHRC-QHGCQNIIGGYRCS--CPQGY 2596
+PGS+ C +C G+ G+ C+DVDEC+ G C C+N G YRC+ C GY
Sbjct: 914 SPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY 972
Query: 2597 LQHYQWNQCVDENECLSAHICGG-ASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSA 2655
Q C D +EC + CG A C N GS++C+C G++ + C D+NEC +
Sbjct: 973 -QPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETL 1031
Query: 2656 QAPCSYG-CSNTEGGYLCGCP--PGYFRIGQGHCV 2687
Q C C N EG +LC CP P F G CV
Sbjct: 1032 QGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1066
Score = 311 bits (796), Expect = 8e-84
Identities = 279/970 (28%), Positives = 371/970 (38%), Gaps = 270/970 (27%)
Query: 55 GPNVCGSRYNAYCCP---GWKTLPGGNQCI-VPICRHS-------------------CGD 91
GP C SR + Y C G++ P G +CI V CR CG
Sbjct: 490 GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGP 549
Query: 92 GFCSRPNMCTC----PSGQIAPSCGSRSIQHC--NIRCM---------NGGSCSD-DHCL 135
GF + P C ++ P C ++ + C+ +G SC D D C
Sbjct: 550 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 609
Query: 136 CQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERD-----YRTGPCFTVI 190
G CG+ C++ L G RC C GF G CE D PC
Sbjct: 610 QSPGL----CGRGACKN--LPGSF-----RCVCPAGFRGSACEEDVDECAQEPPPC---- 654
Query: 191 SNQMCQGQLSGIVCTKTLCCATV-GRAWGHPC---EMCPAQPHPCR-------------- 232
C C C A R G PC + C P PC
Sbjct: 655 GPGRCDNTAGSFHCA---CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCV 711
Query: 233 --RGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECK-CPAGHKLNEVSQKCEDI 289
GF PN C+DVDEC+ C G C+N+ GSF+C+ CP+GH L+ +C D+
Sbjct: 712 CPMGFQPNTAGSECEDVDECENHLA-CPGQECVNSPGSFQCRTCPSGHHLHR--GRCTDV 768
Query: 290 DECST-IPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQ 348
DECS+ P G CTNT S+ C C PG Y +P G RPG C
Sbjct: 769 DECSSGAPPCGPHGHCTNTEGSFRCSCAPG-YRAPSG------RPGPC------------ 809
Query: 349 LPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGP 408
+ C + C+ G + F C+
Sbjct: 810 -----ADVNECLEGDFCFPHGEC-------LNTDGSFACTCA------------------ 839
Query: 409 IPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPT 468
PG+ PGP+ V + D CQ +G C T
Sbjct: 840 --------PGYRPGPR-------------GASCLDVDECSEEDLCQ-------SGICTNT 871
Query: 469 PGSCRCECNKGFQL--DLRGECIDVDEC-EKNP--CAGGECINNQGSYTC--QCRAGYQS 521
GS C C G + DL C+DVDEC E+ P C C N+ GSY C C GY +
Sbjct: 872 DGSFECICPPGHRAGPDL-ASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA 930
Query: 522 TLTRTECRDIDECLQNG-RICNNGRCINTDGSFHC--VCNAGFHVTRDGKNCEDMDECSI 578
T C D+DEC + G IC RC NT GS+ C C+ G+ T G C+D+DEC
Sbjct: 931 GPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PGGGCQDVDECRN 988
Query: 579 RNMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYR 636
R+ C + +C N GSF+C+C G++ A DGR+C D+NECET G+C C N +GS+
Sbjct: 989 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1048
Query: 637 CEC--FPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGA----------------- 677
C C P + GR CV + + G + P+ A
Sbjct: 1049 CVCPNSPEEFDPMTGR-CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQG 1107
Query: 678 --------------------------VTKSECCCASTEYAFGEPC--QPCPAQNSAEYQA 709
VT ECCC E +G C Q CP +AEYQ+
Sbjct: 1108 PVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGE-GWGSGCRIQQCPGTETAEYQS 1166
Query: 710 LCSSGPGM------TSAGSDINECALDPD-ICPNGICENLRGTYKCICNSGYEVDSTGKN 762
LC G G S D++EC L D +C +G+C N Y C C++GY +
Sbjct: 1167 LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1226
Query: 763 CVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCK 822
C+D +EC C+ G+C NT GS+ CTC + + C
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC----------------- 1269
Query: 823 NSPGSFICECSSESTLDPTKTICIETIKGTCWQTV-IDGRC-EININGATLKSQCCSSLG 880
S+ES ++ G CWQ V D C ++ ++CC G
Sbjct: 1270 ---------VSNESQ-------SLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYG 1313
Query: 881 AAWGSPCTLC 890
AWG C LC
Sbjct: 1314 EAWGMDCALC 1323
Score = 202 bits (514), Expect = 4e-51
Identities = 111/307 (36%), Positives = 148/307 (48%), Gaps = 13/307 (4%)
Query: 2399 NGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN-F 2457
+G C+ VC G C++ Y C C +G+ GT C+D++EC + P PC
Sbjct: 475 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG 534
Query: 2458 ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPGF- 2515
C+N+ GS++C C G+ C D+DEC C C NT G F C CP G+
Sbjct: 535 RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 594
Query: 2516 -TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDEC-E 2572
H SC D +ECT LCG +G C+N PGSF C C GF GS+CE DVDEC +
Sbjct: 595 AAPHGASCQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQ 649
Query: 2573 GNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHNTLGSYK 2630
C G C N G + C+CP G+ C D +EC S C C NT GS++
Sbjct: 650 EPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQ 709
Query: 2631 CMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGM 2690
C+CP GFQ C+D++EC + A C N+ G + C P + +G C
Sbjct: 710 CVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVD 769
Query: 2691 GMGRGNP 2697
G P
Sbjct: 770 ECSSGAP 776
Score = 197 bits (502), Expect = 1e-49
Identities = 179/627 (28%), Positives = 244/627 (38%), Gaps = 133/627 (21%)
Query: 55 GPNVCGS----------RYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPS 104
GP +CG+ R C PG++ PGG V CR+ FC +C
Sbjct: 946 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNR---SFCGAHAVCQNLP 1002
Query: 105 GQIAPSC-----GSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG------ 153
G C G+R +HC + C +G CG +CE+
Sbjct: 1003 GSFQCLCDQGYEGARDGRHC---------VDVNECETLQGV----CGAALCENVEGSFLC 1049
Query: 154 -CLNG--------GRCVAPNRCACTYGFTGPQCERDY------------------RTGPC 186
C N GRCV P A T+ + PQ R GP
Sbjct: 1050 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1109
Query: 187 --------FTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPC--EMCPAQPH------- 229
F + C L+ V T CC TVG WG C + CP
Sbjct: 1110 GSGRRECYFDTAAPDACDNILARNV-TWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLC 1168
Query: 230 PCRRGFI-PNIRTGACQDVDECQAIPG-LCQGGNCINTVGSFECKCPAGHKLNEVSQKCE 287
P RG++ P+ +DVDECQ +C+ G C+NT + C C G+ + +C
Sbjct: 1169 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI 1228
Query: 288 DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI-------DVRPGYCYTAL 340
D DEC+ CEGG C NTV SY C C P RC+ D G C+ +
Sbjct: 1229 DNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEV 1288
Query: 341 -TNGRCSN-QLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSV---PMVI 395
+ CS+ +L + T +CCC G W G+ A +CP + ++DF LC+V P
Sbjct: 1289 GADLVCSHPRLDRQATYTECCCLYGEAW--GMDCA--LCPAQDSDDFEALCNVLRPPAYS 1344
Query: 396 PGRP-------EYPPPPLGPIPPVLPVPPGFPPGPQIPV-PRPPVEYLYPSREPPRVLP- 446
P RP EY P LGP LP P P P +P P PP + RE P P
Sbjct: 1345 PPRPGGFGLPYEYGPD-LGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPR 1403
Query: 447 VNVTDY-------------------CQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE 487
++ D+ + R P P + L E
Sbjct: 1404 FDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYE 1463
Query: 488 CIDVDECE-KNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQN---GRICNN 543
++ +EC + C G C+ +TC+C GY+ +TR C DI+EC + +C N
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 544 GRCINTDGSFHCVCNAGFHVTRDGKNC 570
RC+NTDGSF C+C GF T +C
Sbjct: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 186 bits (472), Expect = 3e-46
Identities = 247/943 (26%), Positives = 324/943 (34%), Gaps = 233/943 (24%)
Query: 57 NVCGSRYNAYCCPGWKTLPGGNQCI-VPICRHS---CGDGFCSRPN---MCTCPSGQIAP 109
N GS ++ C G+++ G C V C S C G C C CP G P
Sbjct: 661 NTAGS-FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMG-FQP 718
Query: 110 SCGSRSIQHCNIRCMNGGSCSDDHCL----------CQKGYIGTHCGQPV----CESG-- 153
+ + + C N +C C+ C G+ H G+ C SG
Sbjct: 719 NTAGSECEDVD-ECENHLACPGQECVNSPGSFQCRTCPSGH-HLHRGRCTDVDECSSGAP 776
Query: 154 -CLNGGRCVAPN---RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLC 209
C G C RC+C G+ P R GPC V N+ +G C
Sbjct: 777 PCGPHGHCTNTEGSFRCSCAPGYRAPSG----RPGPCADV--NECLEGDF----CFPHGE 826
Query: 210 CATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSF 269
C ++ C P G+ P R +C DVDEC LCQ G C NT GSF
Sbjct: 827 CLNTDGSFA-----CTCAP-----GYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSF 875
Query: 270 ECKCPAGHKLNEVSQKCEDIDECSTI-PGICEGGECTNTVSSYFC--KCPPGFYTSPDGT 326
EC CP GH+ C D+DEC P +C C N+ SY C C PG++ P+GT
Sbjct: 876 ECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 935
Query: 327 -----RCIDVRPGYC---------------------YTALTNGRCSN------------- 347
C + P C Y G C +
Sbjct: 936 CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAH 995
Query: 348 ----QLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPM---------- 393
LP S QC CD G G + E +C +
Sbjct: 996 AVCQNLPGSF---QCLCDQGY---EGARDGRHCVDVNECETLQGVCGAALCENVEGSFLC 1049
Query: 394 VIPGRPE---------YPP----------PPLGPIPPVLPVPPGFPPGPQIP-VPRP-PV 432
V P PE PP P P PVLP P PP P+ P PR PV
Sbjct: 1050 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1109
Query: 433 -----EYLYPSREPP---RVLPVNVT--DYCQLVRYLCQNG-RCIPTPGS------CRCE 475
E + + P +L NVT + C V +G R PG+ C
Sbjct: 1110 GSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1169
Query: 476 CNKGF-----QLDLRGECIDVDECE---KNPCAGGECINNQGSYTCQCRAGYQSTLTRTE 527
+G+ L LR DVDEC+ C G C+N Y+C C GY R E
Sbjct: 1170 HGRGYLAPSGDLSLRR---DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1226
Query: 528 CRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMC 587
C D DEC C GRC+NT GS+HC C + + C + S+ + G+C
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL--GVC 1284
Query: 588 INEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGL 647
E G+ P +L Y EC C+ G D C P A
Sbjct: 1285 WQEVGADLVCSHP--RLDRQATY----TEC----CCLYGEAWGMD----CALCP--AQDS 1328
Query: 648 DGRVCVDTHMRSTCY-----GG----YKRGQCIKPLFGAVTKSECC-------------- 684
D + +R Y GG Y+ G + P + +
Sbjct: 1329 DDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPP 1388
Query: 685 ---CASTEYAFGEPCQPCPAQNS-----AEYQALCSSGPG--MTSAGSDINECALDPDIC 734
A E +G P P E +A GPG D +P+
Sbjct: 1389 PGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEP 1448
Query: 735 PNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPK 794
P G G+Y YE + + C ++ C NG+C P F C C
Sbjct: 1449 PEG------GSYAGSLAEPYE-ELEAEECGILDGCT-------NGRCVRVPEGFTCRCFD 1494
Query: 795 GFIYKPDLKTCEDIDECE----SSP-CINGVCKNSPGSFICEC 832
G+ C DI+EC+ +SP C+N C N+ GSF C C
Sbjct: 1495 GYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
Score = 142 bits (357), Expect = 6e-33
Identities = 82/229 (35%), Positives = 111/229 (48%), Gaps = 22/229 (9%)
Query: 2500 CVNTIGGFTCKCPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFS 2557
C++ G+TC C GF + T CID +EC C + G C+N+PGSF C C GF
Sbjct: 494 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFRCVCGPGFR 552
Query: 2558 LDQTGSSCEDVDECEGNHR----CQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECL 2612
+ C DVDEC HR C G C+N G + C CP GY C D +EC
Sbjct: 553 AGPRAAECLDVDEC---HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 609
Query: 2613 -SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ-DINECGSAQAPCSYG-CSNTEGG 2669
S +CG +C N GS++C+CPAGF+ C+ D++EC PC G C NT G
Sbjct: 610 QSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGS 665
Query: 2670 YLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYEC 2718
+ C CP G+ G G + +P P G ++ E ++C
Sbjct: 666 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT----EGSFQC 710
Score = 74.7 bits (182), Expect = 1e-12
Identities = 33/77 (42%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 572 DMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE----TPGICMNGR 627
+ +EC I + C NG C+ F C C G++L C DINEC+ +C+N R
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
Query: 628 CVNTDGSYRCECFPGLA 644
C+NTDGS+RC C PG A
Sbjct: 1526 CLNTDGSFRCICRPGFA 1542
Score = 72.0 bits (175), Expect = 8e-12
Identities = 58/206 (28%), Positives = 92/206 (44%), Gaps = 17/206 (8%)
Query: 2324 ASPNQDECLD-NREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPH-CEICPFQ 2381
++P +D D + GYCF E+ C S T+ CC G WG H C++C +
Sbjct: 206 SAPREDGYSDASGFGYCFRELRGGEC--ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSER 263
Query: 2382 GTVAFKKLCPHG---RGF-MTNGA--DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTP 2435
+ + P G GF NG+ D+DEC C++GEC N RG Y C+C G+
Sbjct: 264 LGNSERVSAPDGPCPTGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLL 322
Query: 2436 DITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHN 2495
D + +SC+ + ++A PC + ++ CS P + + C + + +
Sbjct: 323 DSSRSSCISQHVISEAKGPCFRVLRDG----GCSLPILRNITKQICCCSRVGKAWGR--G 376
Query: 2496 CQFLCVNTIGGFTCKCPPGFTQHHTS 2521
CQ GF CP G H+++
Sbjct: 377 CQLCPPFGSEGFREICPAGPGYHYSA 402
Score = 66.2 bits (160), Expect = 4e-10
Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Query: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQA----PKPCNF 2457
+ +EC ++ D C NG CV + C C GY D+T +CVD+NEC++A P N
Sbjct: 1466 EAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 2458 ICKNTEGSYQCSCPKGYILQEDGRSC 2483
C NT+GS++C C G+ C
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 63.9 bits (154), Expect = 2e-09
Identities = 34/77 (44%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINEC---VLNSLLCDNG 779
+ EC + D C NG C + + C C GY +D T CVDINEC S LC N
Sbjct: 1466 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 780 QCRNTPGSFVCTCPKGF 796
+C NT GSF C C GF
Sbjct: 1525 RCLNTDGSFRCICRPGF 1541
Score = 62.0 bits (149), Expect = 8e-09
Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPG---ICEGG 302
+ +EC + G C G C+ F C+C G++L+ C DI+EC +C
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP 333
C NT S+ C C PGF + C RP
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1555
Score = 53.1 bits (126), Expect = 4e-06
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 2537 SKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE----GNHRCQHG-CQNIIGGYRCS 2591
+ G C P FTC C G+ LD T +C D++EC+ + C + C N G +RC
Sbjct: 1477 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1536
Query: 2592 CPQGYLQHYQWNQC 2605
C G+ +Q + C
Sbjct: 1537 CRPGFAPTHQPHHC 1550
Score = 52.0 bits (123), Expect = 8e-06
Identities = 22/47 (46%), Positives = 31/47 (65%), Gaps = 4/47 (8%)
Query: 2633 CPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGY 2678
CP GF E+ +G C+D++EC + C +G C+NT GGY C CP G+
Sbjct: 277 CPTGF--ERVNGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGF 320
Score = 52.0 bits (123), Expect = 8e-06
Identities = 28/76 (36%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 2567 DVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAH----ICGGAS 2621
+ +EC C +G C + G+ C C GY CVD NEC A +C A
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
Query: 2622 CHNTLGSYKCMCPAGF 2637
C NT GS++C+C GF
Sbjct: 1526 CLNTDGSFRCICRPGF 1541
Score = 51.6 bits (122), Expect = 1e-05
Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 18/109 (16%)
Query: 2494 HNCQFLCVNTIGGFTC------KCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGS 2547
H+CQ LC +G CP GF + + SC D +EC + C G C NT G
Sbjct: 255 HDCQ-LCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATG-GRC-QHGECANTRGG 311
Query: 2548 FTCECQRGFSLDQTGSSC---EDVDECEGNHRCQHGCQNIIGGYRCSCP 2593
+TC C GF LD + SSC + E +G C ++ CS P
Sbjct: 312 YTCVCPDGFLLDSSRSSCISQHVISEAKG------PCFRVLRDGGCSLP 354
Score = 50.4 bits (119), Expect = 2e-05
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 7/100 (7%)
Query: 2565 CEDVDECEGNHRCQHGCQNIIGGYRCS-----CPQGYLQHYQWNQCVDENECLSAHICGG 2619
C G H CQ + + R S CP G+ + C D +EC + C
Sbjct: 245 CRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVN--GSCEDVDECATGGRCQH 302
Query: 2620 ASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPC 2659
C NT G Y C+CP GF + C + A+ PC
Sbjct: 303 GECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 342
Score = 48.5 bits (114), Expect = 9e-05
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Query: 2606 VDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAP----CSY 2661
++ EC C C + C C G++ + C DINEC A+A +
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 2662 GCSNTEGGYLCGCPPGYFRIGQGH 2685
C NT+G + C C PG+ Q H
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTHQPH 1548
Score = 45.1 bits (105), Expect = 0.001
Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 4/81 (4%)
Query: 2443 VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDEC----ATKQHNCQF 2498
++ EC N C + C C GY L +C D++EC A
Sbjct: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 2499 LCVNTIGGFTCKCPPGFTQHH 2519
C+NT G F C C PGF H
Sbjct: 1525 RCLNTDGSFRCICRPGFAPTH 1545
Score = 40.0 bits (92), Expect = 0.033
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 910 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDI 953
+ +EC + G C NG CV F C+C G LD T C+DI
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDI 1508
Score = 38.1 bits (87), Expect = 0.13
Identities = 22/50 (44%), Positives = 28/50 (56%), Gaps = 6/50 (12%)
Query: 896 CGKGYSRIKGTQ--CEDIDEC---EVFPGVCKNGLCVNTRGSFKCQCPSG 940
C GY R+ T+ C DI+EC E +C N C+NT GSF+C C G
Sbjct: 1492 CFDGY-RLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1540
Score = 36.6 bits (83), Expect = 0.37
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 14/74 (18%)
Query: 119 CNIRCMNGGSCSDDHCLCQ-KGYIGTHCGQP-------------VCESGCLNGGRCVAPN 164
C +RC++G + S C + G P +C C NGG CV P+
Sbjct: 41 CGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPD 100
Query: 165 RCACTYGFTGPQCE 178
RC C F G C+
Sbjct: 101 RCLCPPDFAGKFCQ 114
Score = 34.3 bits (77), Expect = 1.8
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 723 DINEC----ALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 763
DINEC A P +C N C N G+++CIC G+ +C
Sbjct: 1507 DINECDEAEAASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 32.0 bits (71), Expect = 9.0
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 8/61 (13%)
Query: 793 PKGFIYKPDLKTCEDIDECESSPC------INGVCKNSPGSFICECSSESTLDPTKTICI 846
P+G Y L E +E E+ C NG C P F C C LD T+ C+
Sbjct: 1449 PEGGSYAGSL--AEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1506
Query: 847 E 847
+
Sbjct: 1507 D 1507
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 547 bits (1409), Expect = e-155
Identities = 372/1114 (33%), Positives = 488/1114 (43%), Gaps = 153/1114 (13%)
Query: 914 CEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAG 973
C+ P VC G C++ + C C SG L G C+D+ +EC
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDV-----------DEC------ 554
Query: 974 RHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECK 1033
R C+ G CE P C GPGF D++EC
Sbjct: 555 --RRVPPPCAPG------RCENSPGSFR------CVCGPGFRAGPRAAE---CLDVDECH 597
Query: 1034 MIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDF 1093
+P C G+C NT GSF C C +G+ +C D+DEC SP LCGRG C N PG F
Sbjct: 598 RVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSF 657
Query: 1094 ECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISAC 1153
C C G+ D+DEC ++P C G C NT GS+ C CP G + + C
Sbjct: 658 RCVCPAGFRGSACEE----DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 713
Query: 1154 IDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCT 1213
D++EC S C GRC N G +QC C G+ C D+DEC C
Sbjct: 714 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV 773
Query: 1214 NSEGSYEC-SCQPGFALMPDQRSCTDIDECEDNPNICDG-GQCTNIPGEYRCLCYDGFMA 1271
NS GS++C +C G L + CTD+DEC C G CTN G +RC C G+ A
Sbjct: 774 NSPGSFQCRTCPSGHHL--HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 831
Query: 1272 SEDMK-TCVDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIG 1329
C DVNEC L + C G C NT GSF C C GY C D++EC
Sbjct: 832 PSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-- 888
Query: 1330 AHNCGKHAVCTNTAGSFKCSCSPGWIG--DGIKCTDLDEC-SNGTHMCSQHADCKNTMGS 1386
+ + +CTNT GSF+C C PG D C D+DEC G +C C+N+ GS
Sbjct: 889 EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR-CENSPGS 947
Query: 1387 YRCL--CKEGY-TGDGFTCTDLDECSE-NLNLCGNGQCLNAPGGYRCE--CDMGFVPSAD 1440
YRC+ C GY G TC D+DEC E +CG +C N PG YRC CD G+ P+
Sbjct: 948 YRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPG 1007
Query: 1441 GKACEDIDECSLPNIC-VFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCI 1498
G C+D+DEC + C C NLPG F+C C+ GYE R G +C DVNEC C
Sbjct: 1008 G-GCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCG 1066
Query: 1499 SGNCVNTPGSYICDCP--PDFELNPTRVGCVDTRSG-------------NCYLDIRP--- 1540
+ C N GS++C CP P+ E +P CV R+ + L RP
Sbjct: 1067 AALCENVEGSFLCVCPNSPE-EFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPP 1125
Query: 1541 ----------RGDNG--------DTA----CSNEIGVGVSKASCCCSLGKAWGTPC--EM 1576
+G G DTA C N + V+ CCC++G+ WG+ C +
Sbjct: 1126 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ 1185
Query: 1577 CPAVNTSEYKILCPGGEGF-RPNPITVILEDIDECQELPG-LCQGGKCINTFGSFQCRCP 1634
CP T+EY+ LCP G G+ P+ + D+DECQ +C+ G C+NT + C C
Sbjct: 1186 CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCS 1245
Query: 1635 TGYYLNEDTRVCDDVNEC--ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNC----- 1687
GYY + C D +EC E P C G C NTVG+Y C C P + C
Sbjct: 1246 NGYYYHTQRLECIDNDECADEEPA-CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNES 1304
Query: 1688 --MDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFA 1745
+D +C++ AD L T CCC Y G AW C CP +D+F
Sbjct: 1305 QSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLY--GEAWGMDCALCPAQDSDDFE 1362
Query: 1746 TLCGSQRP---------GFVIDI---------YTGLPVDIDECREIPGVCENGVCINMVG 1787
LC RP GF + Y GLP E P + +
Sbjct: 1363 ALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYG-PELYPPPALPYDPYPPPPGP 1421
Query: 1788 SFRCECPVGF-------FYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKP--- 1837
R E P G F +D E GP + +T S+ +P
Sbjct: 1422 FARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEG 1481
Query: 1838 GYRFTSTGQCNDRNECQE--IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC 1895
G S + + E +E I + C++G+C+ F C C G++ + + C+DINEC
Sbjct: 1482 GSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINEC 1541
Query: 1896 ER-----DACGNGTCRNTIGSFNCRCNHGFILSH 1924
+ C N C NT GSF C C GF +H
Sbjct: 1542 DEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1575
Score = 490 bits (1262), Expect = e-138
Identities = 343/1175 (29%), Positives = 483/1175 (41%), Gaps = 263/1175 (22%)
Query: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGT-PCEMCPAVNTSEYKILCP 1590
G C+ ++R G+ C++ + ++ CC G AWG C++C + ++ P
Sbjct: 250 GYCFRELR----GGE--CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP 303
Query: 1591 GGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVN 1650
G CPTG+ + C+DV+
Sbjct: 304 DGP---------------------------------------CPTGFERVNGS--CEDVD 322
Query: 1651 ECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMR-----RSLCYRNYYADNQT 1705
EC T G C G C NT G YTC+CP ++ + ++C+ + C+R +
Sbjct: 323 ECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFR--VLRDGG 380
Query: 1706 CDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDI----YT 1761
C +L N+TK++CCCS +G+AW + C+ CP ++ F +C + PG+ Y
Sbjct: 381 CSLPILRNITKQICCCS-RVGKAWGRGCQLCPPFGSEGFREICPAG-PGYHYSASDLRYN 438
Query: 1762 GLP-------VDIDECREIPGVCENGVCINMVGSFRCEC---------PVGFFYNDKLLV 1805
P V + + R +P + + R E P +
Sbjct: 439 TRPLGQEPPRVSLSQPRTLPATSRPSA--GFLPTHRLEPRPEPRPDPRPGPELPLPSIPA 496
Query: 1806 CEDIDECQNGP---VCQRNAE------CINTAGSYRCDCKPGYRFTSTG-QCNDRNECQE 1855
+ ++GP +CQRN + CI+ Y C C G+R + G +C D +EC+
Sbjct: 497 WTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRR 556
Query: 1856 IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER--DACGNGTCRNTIGSFN 1913
+P C+ G+C ++ GSF C+C GF+ CLD++EC R C G C NT GSF
Sbjct: 557 VPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFL 616
Query: 1914 CRCNHGFILS-HNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCV 1972
C C G+ + H C DVDEC G LC G C N GSF+C C G+ G C
Sbjct: 617 CVCPAGYQAAPHGASCQDVDECTQSPG-LCGRGACKNLPGSFRCVCPAGFR----GSACE 671
Query: 1973 -DINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTC 2029
D++EC EP C PG C N GS+ C CP G+ + C+D+DEC P C G C
Sbjct: 672 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRC 731
Query: 2030 SNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC----------SSPKSRNHS 2079
NTEGSF+C+CP GF +++G C+D+ + G +C + P +
Sbjct: 732 ENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH 791
Query: 2080 KQECCCALKGEGWGDPCEL---CPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDV 2136
+ C + PC C T + +FR C G G D++EC E D
Sbjct: 792 RGRCTDVDECSSGAPPCGPHGHC-TNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDF 850
Query: 2137 C-KHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVIGGFECTCE 2193
C HG+C+NTDGS+ C C GY G C+D DECS + C +G C N G FEC C
Sbjct: 851 CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICP 910
Query: 2194 EGFEPGP-MMTCEDINECAQN-PLLCAF-RCVNTYGSYEC--KCPVGYVLREDRRMCKDE 2248
G GP + +C D++EC + P LC RC N+ GSY C C GY + C D
Sbjct: 911 PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDV 969
Query: 2249 DECEE---------------GKHDCTEK---------------------------QMECK 2266
DEC+E G + CT C+
Sbjct: 970 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQ 1029
Query: 2267 NLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCEC-NDGFTAS 2325
NL G++ C+C GY+ DG CVD NEC+T G+C C N GS+ C C N
Sbjct: 1030 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD 1089
Query: 2326 PNQDECLDNREGYCFTEVLQNMCQ-------------------------IGSSNRN---- 2356
P C+ R Q +GS R
Sbjct: 1090 PMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFD 1149
Query: 2357 -------------PVTKSECCCDGGRGWGPHCEI--CPFQGTVAFKKLCPHGRGFMTNGA 2401
VT ECCC G GWG C I CP T ++ LCPHGRG++
Sbjct: 1150 TAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG 1209
Query: 2402 D------IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC 2455
D +DEC++ D +CK+G
Sbjct: 1210 DLSLRRDVDECQLFRDQ---------------VCKSG----------------------- 1231
Query: 2456 NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPG 2514
+C NT Y C C GY C D DECA ++ C+ CVNT+G + C C P
Sbjct: 1232 --VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1289
Query: 2515 FTQHHTS--CIDNNECTSDINLCGSKGICQNTPGS 2547
+ C+ N + D NL G+C G+
Sbjct: 1290 LVLDGSQRRCVSNESQSLDDNL----GVCWQEVGA 1320
Score = 478 bits (1230), Expect = e-134
Identities = 412/1505 (27%), Positives = 557/1505 (37%), Gaps = 299/1505 (19%)
Query: 958 CFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATK 1017
CF EC P+ G + CC G AWG +C+ C R P GP
Sbjct: 252 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP----- 306
Query: 1018 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 1077
C +GF + +C D+DEC
Sbjct: 307 -------------------------------------CPTGF--ERVNGSCEDVDECATG 327
Query: 1078 PDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG-GVCHNTEGSY 1136
C G+C NT G + C C + GF++ + C ++ G C
Sbjct: 328 -GRCQHGECANTRGGYTCVCPD----GFLLDSSR---SSCISQHVISEAKGPCFRVLRDG 379
Query: 1137 RCECPPGHQLSPNISACIDINEC-ELSAHLCPNGRCVNLIGKYQCACNPGY-HSTPDRLF 1194
C P ++ I C + + LCP + C PGY +S D +
Sbjct: 380 GCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGF--REICPAGPGYHYSASDLRY 437
Query: 1195 C----------VDIDECSIMN-------GGCETFCTNSEGSYECSCQPGFAL-MPDQRSC 1236
V + + + G T +PG L +P +
Sbjct: 438 NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW 497
Query: 1237 T--DIDE-------CEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLN 1287
T +I E C+ NP +C G+C + P Y C C GF S C+DV+EC
Sbjct: 498 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 557
Query: 1288 PNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFK 1347
P C G CEN+ GSF C C G+ C D++EC C C NT GSF
Sbjct: 558 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFL 616
Query: 1348 CSCSPGWIG--DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDL 1405
C C G+ G C D+DEC+ +C + A CKN GS+RC+C G+ G D+
Sbjct: 617 CVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE-EDV 674
Query: 1406 DECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNL 1464
DEC++ CG G+C N G + C C GF G C+D+DEC+ P C +G C N
Sbjct: 675 DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT 734
Query: 1465 PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYIC-DCPPDFELNPTR 1523
G F+C C +G++ + +G C DV+EC + C CVN+PGS+ C CP L+ R
Sbjct: 735 EGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR 794
Query: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS 1583
VD C P G +G C+N G C C+ G
Sbjct: 795 CTDVD----ECSSGAPPCGPHGH--CTNTEG----SFRCSCAPG---------------- 828
Query: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDT 1643
Y+ P G RP P D++EC E G+C+NT GSF C C GY
Sbjct: 829 -YR--APSG---RPGPCA----DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRG 878
Query: 1644 RVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADN 1703
C DV+EC +C G C NT G++ CICPP + +C+D+ +
Sbjct: 879 ASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 938
Query: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGL 1763
Q C+ + C Y+ G P + D
Sbjct: 939 QRCENSPGSYRCVRDCDPGYHAG----------PEGTCD--------------------- 967
Query: 1764 PVDIDECREI-PGVCENGVCINMVGSFRCE--CPVGFFYNDKLLVCEDIDECQNGPVCQR 1820
D+DEC+E P +C C N GS+RC C G+ C+D+DEC+N C
Sbjct: 968 --DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGA 1024
Query: 1821 NAECINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTG 1879
+A C N GS++C C GY G+ C D NEC+ + +C C + GSF C+C
Sbjct: 1025 HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNS 1084
Query: 1880 FKTNDDQTMCLDINECERDACGNGTC------------------------------RNTI 1909
+ D T C GT + +
Sbjct: 1085 PEEFDPMT-----GRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1139
Query: 1910 GSFNCRCNHGF--------ILSHNNDCIDVDECA----SGNGNLCRNGQCINT-VGSFQC 1956
GS C IL+ N + EC G G+ CR QC T +Q
Sbjct: 1140 GSGRRECYFDTAAPDACDNILARN---VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQS 1196
Query: 1957 QCNEGYE-VAPDGRTCV--DINEC-LLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK-- 2010
C G +AP G + D++EC L + C G C N Y C C GY ++
Sbjct: 1197 LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1256
Query: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ-------DLRMSYCYA 2063
C D DEC +E C G C NT GS+ C C L S RRC D + C+
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1316
Query: 2064 KFEGGK-CSSPK-SRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC---------- 2111
+ CS P+ R + ECCC L GE WG C LCP + + F +C
Sbjct: 1317 EVGADLVCSHPRLDRQATYTECCC-LYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSP 1375
Query: 2112 --------PYGSGIIVGPDDSAVDMD-ECKEPDVCKHGQCINTDGSY-RCECPFGYILAG 2161
PY G +GP + E P + G + R E P+G
Sbjct: 1376 PRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFD 1435
Query: 2162 NECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMM--------TCEDINECAQN 2213
+ D G P G E PGP T E +
Sbjct: 1436 MPDFEDD----GGPYGES-------------EAPAPPGPGTRWPYRSRDTRRSFPEPEEP 1478
Query: 2214 PLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYM 2273
P GSY Y E C D C G+ C + +
Sbjct: 1479 P---------EGGSYAGSLAEPYEELEAEE-CGILDGCTNGR---------CVRVPEGFT 1519
Query: 2274 CICGPGYQRRPDGEGCVDENEC---QTKPGICENGRCLNTRGSYTCECNDGFTASPNQDE 2330
C C GY+ CVD NEC + +C N RCLNT GS+ C C GF +
Sbjct: 1520 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHH 1579
Query: 2331 CLDNR 2335
C R
Sbjct: 1580 CAPAR 1584
Score = 463 bits (1192), Expect = e-130
Identities = 346/1178 (29%), Positives = 491/1178 (41%), Gaps = 215/1178 (18%)
Query: 531 IDEC-LQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCIN 589
+ +C L + R+ N+ R DG C GF R +CED+DEC+ C +G C N
Sbjct: 284 VHDCQLCSERLGNSERVSAPDGP----CPTGFE--RVNGSCEDVDECATGGRCQHGECAN 337
Query: 590 EDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCECFPGLAVGLD 648
G + C+C GF L S C + E G C V DG C + +
Sbjct: 338 TRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFR---VLRDGG----CSLPILRNIT 390
Query: 649 GRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFG-------------EP 695
++C + + + RG + P FG+ E C A Y + EP
Sbjct: 391 KQICCCSRVGKA----WGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP 446
Query: 696 CQ---------PCPAQNSAEYQAL-------------------------CSSGPGMTSAG 721
+ P ++ SA + +GP + +G
Sbjct: 447 PRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESG 506
Query: 722 SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQC 781
C +P +C G C + Y C C+SG+ + G C+D++EC C G+C
Sbjct: 507 PSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRC 566
Query: 782 RNTPGSFVCTCPKGFIYKPDLKTCEDIDECE--SSPCINGVCKNSPGSFICECSSESTLD 839
N+PGSF C C GF P C D+DEC PC G C+N+PGSF+C C +
Sbjct: 567 ENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAA 626
Query: 840 PTKTICIETIK-----GTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPC-----TL 889
P C + + G C + G C+ N+ G+ +C G GS C
Sbjct: 627 PHGASCQDVDECTQSPGLCGR----GACK-NLPGS---FRCVCPAGFR-GSACEEDVDEC 677
Query: 890 CQVDPICGKG-----------------YSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGS 932
Q P CG G SR G C+D+DEC P C G C NT GS
Sbjct: 678 AQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGS 737
Query: 933 FKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEE 992
F+C CP G + G C D+ L +EC + G+ +
Sbjct: 738 FQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV-----------------NSPGSFQ 780
Query: 993 CEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKM-IPSLCTHGKCRNTIGSF 1051
C CP + + G+ D++EC P HG C NT GSF
Sbjct: 781 CRTCP-----------------SGHHLHRGR--CTDVDECSSGAPPCGPHGHCTNTEGSF 821
Query: 1052 KCRCDSGFALDSEERN-CTDIDECRISPDLC-GRGQCVNTPGDFECKCDEGYESGFMMMK 1109
+C C G+ S C D++EC + D C G+C+NT G F C C GY G
Sbjct: 822 RCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPG-PRGA 879
Query: 1110 NCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINEC-ELSAHLCPN 1168
+C+D+DEC + LC+ G+C NT+GS+ C CPPGH+ P++++C+D++EC E LC +
Sbjct: 880 SCLDVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 938
Query: 1169 GRCVNLIGKYQCA--CNPGYHSTPDRLFCVDIDECSIMNG---GCETFCTNSEGSYEC-- 1221
RC N G Y+C C+PGYH+ P+ C D+DEC G + C N+ GSY C
Sbjct: 939 QRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQR-CENTPGSYRCTP 996
Query: 1222 SCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDV 1281
+C PG+ P C D+DEC + C N+PG ++CLC G+ + D + CVDV
Sbjct: 997 ACDPGYQPTPG-GGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 1055
Query: 1282 NECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTN 1341
NEC+ +C + CEN +GSF+C C TG G + +
Sbjct: 1056 NECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPAS 1115
Query: 1342 TAGSFKCSCSP----------GWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGS----Y 1387
+ P G +G G + EC T + C N +
Sbjct: 1116 PVLPARPPPPPLPRRPSTPRQGPVGSGRR-----ECYFDT---AAPDACDNILARNVTWQ 1167
Query: 1388 RCLCKEGYTGDGFTCTDLDEC-----SENLNLCGNGQCLNAPGGYRCECDMGFVPSADGK 1442
C C G G G C + +C +E +LC +G+ GY PS D
Sbjct: 1168 ECCCTVG-EGWGSGCR-IQQCPGTETAEYQSLCPHGR------GY-------LAPSGDLS 1212
Query: 1443 ACEDIDECSL--PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCIS 1499
D+DEC L +C G C N + C C GY C D +EC D C
Sbjct: 1213 LRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG 1272
Query: 1500 GNCVNTPGSYICDCPPDFELNPTRVGCVDTRS-------GNCYLDIRPRGDNGDTACSN- 1551
G CVNT GSY C C P L+ ++ CV S G C+ ++ D CS+
Sbjct: 1273 GRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEV-----GADLVCSHP 1327
Query: 1552 EIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILC 1589
+ + CCC G+AWG C +CPA ++ +++ LC
Sbjct: 1328 RLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC 1365
Score = 451 bits (1159), Expect = e-126
Identities = 329/1091 (30%), Positives = 440/1091 (40%), Gaps = 229/1091 (20%)
Query: 184 GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG-HPCEMCPAQPHPCRRGFIPNIRTG 242
G CF + C L G+ T+ +CC G AWG H C++C + R P
Sbjct: 250 GYCFRELRGGECASPLPGLR-TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP----- 303
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
+ CP G + V+ CED+DEC+T G C+ G
Sbjct: 304 ---------------------------DGPCPTGFE--RVNGSCEDVDECAT-GGRCQHG 333
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVR-----PGYCYTALTNGRCSNQLPQSITKMQ 357
EC NT Y C CP GF + CI G C+ L +G CS + ++ITK
Sbjct: 334 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQI 393
Query: 358 CCCD-AGRCWSPGVTVAPEMCPIRATEDFNKLC--------------------------- 389
CCC G+ W G ++CP +E F ++C
Sbjct: 394 CCCSRVGKAWGRGC----QLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRV 449
Query: 390 --SVPMVIP--GRPE---YPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPP 442
S P +P RP P L P P P P PGP++P+P P + E P
Sbjct: 450 SLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDP---RPGPELPLPSIPA---WTGPEIP 503
Query: 443 RVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRG-ECIDVDECEK--NPC 499
P + CQ +C GRCI P C C+ GF+L +G CIDVDEC + PC
Sbjct: 504 ESGP--SSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC 561
Query: 500 AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNA 559
A G C N+ GS+ C C G+++ EC D+DEC + C+ GRC NT GSF CVC A
Sbjct: 562 APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPA 621
Query: 560 GFHVTRDGKNCEDMDECSI------RNMCLN----------------------------- 584
G+ G +C+D+DEC+ R C N
Sbjct: 622 GYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEP 681
Query: 585 -----GMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCE 638
G C N GSF C C GF+ G C+D++EC +P C GRC NT+GS++C
Sbjct: 682 PPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCV 741
Query: 639 CFPGLAVGLDGRVCVD-----THMR---STCYGGYKRGQCIKPLFGAVTKSECCCASTEY 690
C G G C D H+ C QC G C E
Sbjct: 742 CPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDEC 801
Query: 691 AFG-EPCQPCPAQNSAEYQALCSSGPGMTSAG------SDINECALDPDIC-PNGICENL 742
+ G PC P + E CS PG + +D+NEC L+ D C P+G C N
Sbjct: 802 SSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNT 860
Query: 743 RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDL 802
G++ C C GY G +C+D++EC LC +G C NT GSF C CP G PDL
Sbjct: 861 DGSFACTCAPGYRPGPRGASCLDVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDL 919
Query: 803 KTCEDIDEC-ESSPCINGV--CKNSPGSFIC--ECSSESTLDPTKTICIETIKGTCWQTV 857
+C D+DEC E P + G C+NSPGS+ C +C P T C + + +
Sbjct: 920 ASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPE 978
Query: 858 IDG--RCEININGATLKSQCCSSLGAAWGSPC---------------TLCQVDP-----I 895
I G RCE C G C +CQ P +
Sbjct: 979 ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1038
Query: 896 CGKGYSRIK-GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCP-SGMTLDATGRICLDI 953
C +GY + G C D++ECE GVC LC N GSF C CP S D C+
Sbjct: 1039 CDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP 1098
Query: 954 RL--------------------------------------------ETCFLRYEDEECTL 969
R E F + C
Sbjct: 1099 RTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDN 1158
Query: 970 PIAGRHRMDACCCSVGAAWGTE-ECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKD 1028
+A CCC+VG WG+ ++CP T EY+ LCP G G+ + +D
Sbjct: 1159 ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAP--SGDLSLRRD 1216
Query: 1029 INECKMI-PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
++EC++ +C G C NT + C C +G+ ++ C D DEC C G+CV
Sbjct: 1217 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1276
Query: 1088 NTPGDFECKCD 1098
NT G + C C+
Sbjct: 1277 NTVGSYHCTCE 1287
Score = 424 bits (1090), Expect = e-118
Identities = 309/980 (31%), Positives = 406/980 (41%), Gaps = 172/980 (17%)
Query: 1453 PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCISGNCVNTPGSYIC 1511
P +C G C + P + C C+ G+ L G C DV+EC P C G C N+PGS+ C
Sbjct: 516 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRC 575
Query: 1512 DCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWG 1571
C P F P C+D C+ P C LG+
Sbjct: 576 VCGPGFRAGPRAAECLDV--DECHRVPPP-----------------------CDLGRCEN 610
Query: 1572 TPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQC 1631
TP + +CP G ++ P +D+DEC + PGLC G C N GSF+C
Sbjct: 611 TP---------GSFLCVCPAG--YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRC 659
Query: 1632 RCPTGYYLNEDTRVCDDVNEC-ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
CP G+ + +DV+EC + P CGPG C NT G++ C CP + G C D+
Sbjct: 660 VCPAGF---RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDV 716
Query: 1691 RRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCE-QCPIPSTDEFATLCG 1749
C R+ C+Y GR N QC P
Sbjct: 717 DE--CARSPPP-------------------CTY--GRCENTEGSFQCVCPM--------- 744
Query: 1750 SQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCE-CPVGFFYNDKLLVCED 1808
GF + D+DEC E C C+N GSF+C CP G + C D
Sbjct: 745 ----GFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR--CTD 797
Query: 1809 IDECQNG-PVCQRNAECINTAGSYRCDCKPGYRFTS--TGQCNDRNECQEIPNICSHGQC 1865
+DEC +G P C + C NT GS+RC C PGYR S G C D NEC E HG+C
Sbjct: 798 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGEC 857
Query: 1866 IDTVGSFYCLCHTGFKTNDDQTMCLDINEC-ERDACGNGTCRNTIGSFNCRCNHGFILSH 1924
++T GSF C C G++ CLD++EC E D C +G C NT GSF C C G
Sbjct: 858 LNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 917
Query: 1925 N-NDCIDVDECASGNGNLCRNGQCINTVGSFQC--QCNEGYEVAPDGRTCVDINECL-LE 1980
+ C+DVDEC LC + +C N+ GS++C C+ GY P+G TC D++EC
Sbjct: 918 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYG 976
Query: 1981 PRKCAPGTCQNLDGSYRCI--CPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFK 2037
P C C+N GSYRC C PGY C+D+DEC A C N GSF+
Sbjct: 977 PEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1036
Query: 2038 CLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCE 2097
CLC +G+ + GR C D+ G C + N C
Sbjct: 1037 CLCDQGYEGARDGRHCVDVNECETLQ----GVCGAALCENVEGSFLC------------- 1079
Query: 2098 LCPTEPDE----AFRQICPYGS-GIIVGPDDSAVDMDEC----------KEPDVCKHGQC 2142
+CP P+E R + P S G G A + P + G
Sbjct: 1080 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1139
Query: 2143 INTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCE--EGFEPGP 2200
GS R EC F + + + C N +NV EC C EG+ G
Sbjct: 1140 ----GSGRRECYF-------------DTAAPDACDNILARNVTWQ-ECCCTVGEGWGSG- 1180
Query: 2201 MMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVG--YVLRE-DRRMCKDEDECEEGKHD 2257
C I +C Y+ CP G Y+ D + +D DEC+ + D
Sbjct: 1181 ---CR-IQQCPGTET----------AEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFR-D 1225
Query: 2258 CTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCE 2317
K C N Y C C GY C+D +EC + CE GRC+NT GSY C
Sbjct: 1226 QVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCT 1285
Query: 2318 CNDGFTASPNQDEC-------LDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRG 2370
C +Q C LD+ G C+ EV ++ T +ECCC G
Sbjct: 1286 CEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEA 1345
Query: 2371 WGPHCEICPFQGTVAFKKLC 2390
WG C +CP Q + F+ LC
Sbjct: 1346 WGMDCALCPAQDSDDFEALC 1365
Score = 379 bits (973), Expect = e-104
Identities = 274/839 (32%), Positives = 357/839 (42%), Gaps = 140/839 (16%)
Query: 1938 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYR 1997
N +C G+CI+ + C C+ G+ ++P G C+D++EC P CAPG C+N GS+R
Sbjct: 515 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 574
Query: 1998 CICPPGYSL--QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQD 2055
C+C PG+ + +C D+DEC P C LG C NT GSF C+CP G+ + G CQD
Sbjct: 575 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 634
Query: 2056 LRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGS 2115
+ +C+ L G G C P +FR +CP G
Sbjct: 635 V-----------DECTQSPG-----------LCGRG------ACKNLPG-SFRCVCPAG- 664
Query: 2116 GIIVGPDDSAVDMDEC-KEPDVCKHGQCINTDGSYRCECPFGYILAGN--ECVDTDECSV 2172
D+DEC +EP C G+C NT GS+ C CP G+ G C D DEC+
Sbjct: 665 ---FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECAR 721
Query: 2173 GNP-CGNGTCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQNPLLCAFR-CVNTYGSYE 2229
P C G C+N G F+C C GF+P + CED++EC +N L C + CVN+ GS++
Sbjct: 722 SPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQ 780
Query: 2230 CK-CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG 2288
C+ CP G+ L R C D DEC G C C N G++ C C PGY R P G
Sbjct: 781 CRTCPSGHHLHRGR--CTDVDECSSGAPPCGPHG-HCTNTEGSFRCSCAPGY-RAPSGRP 836
Query: 2289 --CVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQN 2346
C D NEC +G CLNT GS+ C C G+ P CLD E C E +
Sbjct: 837 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE--CSEE---D 891
Query: 2347 MCQIGSSNRNPVTKSECCCDGGRGWGP----------------------HCEICPFQGTV 2384
+CQ G N EC C G GP CE P G+
Sbjct: 892 LCQSGICT-NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP--GSY 948
Query: 2385 AFKKLCPHGRGFMTNGA--DIDECKVIH-DVCRNGECVNDRGSYHCI--CKTGYTPDITG 2439
+ C G G D+DEC+ ++C C N GSY C C GY P G
Sbjct: 949 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PG 1007
Query: 2440 TSCVDLNEC-NQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC-Q 2497
C D++EC N++ + +C+N GS+QC C +GY DGR C D++EC T Q C
Sbjct: 1008 GGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGA 1067
Query: 2498 FLCVNTIGGFTCKC---PPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQ- 2553
LC N G F C C P F C+ TS GS+ P S +
Sbjct: 1068 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR--TSAGTFPGSQ---PQAPASPVLPARP 1122
Query: 2554 ------RGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGG-------------------- 2587
R S + G EC + C NI+
Sbjct: 1123 PPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR 1182
Query: 2588 -----------YRCSCP--QGYLQ---HYQWNQCVDENECLSAHICGGASCHNTLGSYKC 2631
Y+ CP +GYL + VDE + +C C NT Y C
Sbjct: 1183 IQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC 1242
Query: 2632 MCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGC-PPGYFRIGQGHCVS 2688
C G+ Y C D +EC + C G C NT G Y C C PP Q CVS
Sbjct: 1243 YCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1301
Score = 367 bits (943), Expect = e-101
Identities = 274/930 (29%), Positives = 378/930 (40%), Gaps = 154/930 (16%)
Query: 172 FTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPC 231
+TGP+ +GP S+ MCQ VC C + R G+ C C
Sbjct: 497 WTGPEIPE---SGP-----SSGMCQRNPQ--VCGPGRC---ISRPSGYTCA--------C 535
Query: 232 RRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDE 291
GF + + C DVDEC+ +P C G C N+ GSF C C G + + +C D+DE
Sbjct: 536 DSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE 595
Query: 292 CSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV-----RPGYCYTALTNGRCS 346
C +P C+ G C NT S+ C CP G+ +P G C DV PG C G C
Sbjct: 596 CHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLC----GRGACK 651
Query: 347 NQLPQSITKMQCCCDAG----RCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPG--RPE 400
N LP S +C C AG C A E P N S P R
Sbjct: 652 N-LPGS---FRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 707
Query: 401 YPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYL- 459
P P + PP G + + + P P D + +L
Sbjct: 708 GPGAPCQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLA 766
Query: 460 CQNGRCIPTPGSCRCE-CNKGFQLDLRGECIDVDECEKN--PCA-GGECINNQGSYTCQC 515
C C+ +PGS +C C G L RG C DVDEC PC G C N +GS+ C C
Sbjct: 767 CPGQECVNSPGSFQCRTCPSGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 825
Query: 516 RAGYQSTLTRT-ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMD 574
GY++ R C D++ECL+ +G C+NTDGSF C C G+ G +C D+D
Sbjct: 826 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 885
Query: 575 ECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET--PGICMNGRCVNTD 632
ECS ++C +G+C N DGSF+CIC PG + D C D++EC P +C + RC N+
Sbjct: 886 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 945
Query: 633 GSYRC--ECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEY 690
GSYRC +C PG G +G C D EC E
Sbjct: 946 GSYRCVRDCDPGYHAGPEG-TCDDV-------------------------DECQEYGPEI 979
Query: 691 AFGEPCQPCPAQNSAEYQALCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKC 748
+ C+ P S C G T G D++EC + +C+NL G+++C
Sbjct: 980 CGAQRCENTP--GSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC 1037
Query: 749 ICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDI 808
+C+ GYE G++CVD+NEC +C C N GSF+C CP + D T +
Sbjct: 1038 LCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNS-PEEFDPMTGRCV 1096
Query: 809 DECESSPCINGVCKNSPGSFICECSSESTLDPTKTIC-----IETIKGTCW-QTVIDGRC 862
S+ G +P S + P + + + + C+ T C
Sbjct: 1097 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDAC 1156
Query: 863 EININGATLKSQCCSSLGAAWGSPCTL--------------------------------- 889
+ + +CC ++G WGS C +
Sbjct: 1157 DNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRD 1216
Query: 890 ---CQV--DPICGKG-----------------YSRIKGTQCEDIDECEVFPGVCKNGLCV 927
CQ+ D +C G Y + +C D DEC C+ G CV
Sbjct: 1217 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1276
Query: 928 NTRGSFKCQCPSGMTLDATGRIC-------LDIRLETCFLRY-EDEECTLPIAGRH-RMD 978
NT GS+ C C + LD + R C LD L C+ D C+ P R
Sbjct: 1277 NTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYT 1336
Query: 979 ACCCSVGAAWGTEECEECPMRNTPEYEELC 1008
CCC G AWG +C CP +++ ++E LC
Sbjct: 1337 ECCCLYGEAWGM-DCALCPAQDSDDFEALC 1365
Score = 351 bits (901), Expect = 5e-96
Identities = 272/815 (33%), Positives = 362/815 (44%), Gaps = 85/815 (10%)
Query: 1925 NNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC 1984
N C DVDECA+G C++G+C NT G + C C +G+ + +C+ + E
Sbjct: 315 NGSCEDVDECATGGR--CQHGECANTRGGYTCVCPDGFLLDSSRSSCIS-QHVISE---- 367
Query: 1985 APGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2044
A G C + C P ++ + C C L +EG F+ +CP G
Sbjct: 368 AKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG-FREICPAGP 426
Query: 2045 SLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPT--- 2101
S DLR + E + S + R + G+ L P
Sbjct: 427 GYHYSA---SDLRYNTRPLGQEPPRVSLSQPRTLP----ATSRPSAGFLPTHRLEPRPEP 479
Query: 2102 EPDEAFRQICPYGS-GIIVGPD--DSAVDMDEC-KEPDVCKHGQCINTDGSYRCECPFGY 2157
PD P S GP+ +S C + P VC G+CI+ Y C C G+
Sbjct: 480 RPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGF 539
Query: 2158 ILA--GNECVDTDECS-VGNPCGNGTCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQN 2213
L+ G C+D DEC V PC G C+N G F C C GF GP C D++EC +
Sbjct: 540 RLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 599
Query: 2214 PLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTY 2272
P C RC NT GS+ C CP GY C+D DEC + C CKNL G++
Sbjct: 600 PPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA--CKNLPGSF 657
Query: 2273 MCICGPGYQRRPDGEGCVDE-NECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDEC 2331
C+C G++ G C ++ +EC +P C GRC NT GS+ C C GF + C
Sbjct: 658 RCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 713
Query: 2332 LDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGG---RGWGPHCE---------ICP 2379
D E C C G N +C C G G CE CP
Sbjct: 714 QDVDE--CARS--PPPCTYGRCE-NTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP 768
Query: 2380 FQGTV----AFK-KLCPHG----RGFMTNGADIDECKVIHDVCR-NGECVNDRGSYHCIC 2429
Q V +F+ + CP G RG T D+DEC C +G C N GS+ C C
Sbjct: 769 GQECVNSPGSFQCRTCPSGHHLHRGRCT---DVDECSSGAPPCGPHGHCTNTEGSFRCSC 825
Query: 2430 KTGY-TPDITGTSCVDLNECNQAPKPC--NFICKNTEGSYQCSCPKGYILQEDGRSCKDL 2486
GY P C D+NEC + C + C NT+GS+ C+C GY G SC D+
Sbjct: 826 APGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDV 884
Query: 2487 DECATKQHNCQFLCVNTIGGFTCKCPPGFTQHH--TSCIDNNECTS-DINLCGSKGICQN 2543
DEC+ + +C NT G F C CPPG SC+D +EC LCGS+ C+N
Sbjct: 885 DECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR-CEN 943
Query: 2544 TPGSFTC--ECQRGFSLDQTGSSCEDVDECE--GNHRC-QHGCQNIIGGYRCS--CPQGY 2596
+PGS+ C +C G+ G+ C+DVDEC+ G C C+N G YRC+ C GY
Sbjct: 944 SPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY 1002
Query: 2597 LQHYQWNQCVDENECLSAHICGG-ASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSA 2655
Q C D +EC + CG A C N GS++C+C G++ + C D+NEC +
Sbjct: 1003 -QPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETL 1061
Query: 2656 QAPCSYG-CSNTEGGYLCGCP--PGYFRIGQGHCV 2687
Q C C N EG +LC CP P F G CV
Sbjct: 1062 QGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1096
Score = 311 bits (796), Expect = 8e-84
Identities = 279/970 (28%), Positives = 371/970 (38%), Gaps = 270/970 (27%)
Query: 55 GPNVCGSRYNAYCCP---GWKTLPGGNQCI-VPICRHS-------------------CGD 91
GP C SR + Y C G++ P G +CI V CR CG
Sbjct: 520 GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGP 579
Query: 92 GFCSRPNMCTC----PSGQIAPSCGSRSIQHC--NIRCM---------NGGSCSD-DHCL 135
GF + P C ++ P C ++ + C+ +G SC D D C
Sbjct: 580 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 639
Query: 136 CQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERD-----YRTGPCFTVI 190
G CG+ C++ L G RC C GF G CE D PC
Sbjct: 640 QSPGL----CGRGACKN--LPGSF-----RCVCPAGFRGSACEEDVDECAQEPPPC---- 684
Query: 191 SNQMCQGQLSGIVCTKTLCCATV-GRAWGHPC---EMCPAQPHPCR-------------- 232
C C C A R G PC + C P PC
Sbjct: 685 GPGRCDNTAGSFHCA---CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCV 741
Query: 233 --RGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECK-CPAGHKLNEVSQKCEDI 289
GF PN C+DVDEC+ C G C+N+ GSF+C+ CP+GH L+ +C D+
Sbjct: 742 CPMGFQPNTAGSECEDVDECENHLA-CPGQECVNSPGSFQCRTCPSGHHLHR--GRCTDV 798
Query: 290 DECST-IPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQ 348
DECS+ P G CTNT S+ C C PG Y +P G RPG C
Sbjct: 799 DECSSGAPPCGPHGHCTNTEGSFRCSCAPG-YRAPSG------RPGPC------------ 839
Query: 349 LPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGP 408
+ C + C+ G + F C+
Sbjct: 840 -----ADVNECLEGDFCFPHGEC-------LNTDGSFACTCA------------------ 869
Query: 409 IPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPT 468
PG+ PGP+ V + D CQ +G C T
Sbjct: 870 --------PGYRPGPR-------------GASCLDVDECSEEDLCQ-------SGICTNT 901
Query: 469 PGSCRCECNKGFQL--DLRGECIDVDEC-EKNP--CAGGECINNQGSYTC--QCRAGYQS 521
GS C C G + DL C+DVDEC E+ P C C N+ GSY C C GY +
Sbjct: 902 DGSFECICPPGHRAGPDL-ASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA 960
Query: 522 TLTRTECRDIDECLQNG-RICNNGRCINTDGSFHC--VCNAGFHVTRDGKNCEDMDECSI 578
T C D+DEC + G IC RC NT GS+ C C+ G+ T G C+D+DEC
Sbjct: 961 GPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PGGGCQDVDECRN 1018
Query: 579 RNMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYR 636
R+ C + +C N GSF+C+C G++ A DGR+C D+NECET G+C C N +GS+
Sbjct: 1019 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1078
Query: 637 CEC--FPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGA----------------- 677
C C P + GR CV + + G + P+ A
Sbjct: 1079 CVCPNSPEEFDPMTGR-CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQG 1137
Query: 678 --------------------------VTKSECCCASTEYAFGEPC--QPCPAQNSAEYQA 709
VT ECCC E +G C Q CP +AEYQ+
Sbjct: 1138 PVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGE-GWGSGCRIQQCPGTETAEYQS 1196
Query: 710 LCSSGPGM------TSAGSDINECALDPD-ICPNGICENLRGTYKCICNSGYEVDSTGKN 762
LC G G S D++EC L D +C +G+C N Y C C++GY +
Sbjct: 1197 LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1256
Query: 763 CVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCK 822
C+D +EC C+ G+C NT GS+ CTC + + C
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC----------------- 1299
Query: 823 NSPGSFICECSSESTLDPTKTICIETIKGTCWQTV-IDGRC-EININGATLKSQCCSSLG 880
S+ES ++ G CWQ V D C ++ ++CC G
Sbjct: 1300 ---------VSNESQ-------SLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYG 1343
Query: 881 AAWGSPCTLC 890
AWG C LC
Sbjct: 1344 EAWGMDCALC 1353
Score = 202 bits (514), Expect = 4e-51
Identities = 111/307 (36%), Positives = 148/307 (48%), Gaps = 13/307 (4%)
Query: 2399 NGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN-F 2457
+G C+ VC G C++ Y C C +G+ GT C+D++EC + P PC
Sbjct: 505 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG 564
Query: 2458 ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPGF- 2515
C+N+ GS++C C G+ C D+DEC C C NT G F C CP G+
Sbjct: 565 RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 624
Query: 2516 -TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDEC-E 2572
H SC D +ECT LCG +G C+N PGSF C C GF GS+CE DVDEC +
Sbjct: 625 AAPHGASCQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQ 679
Query: 2573 GNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHNTLGSYK 2630
C G C N G + C+CP G+ C D +EC S C C NT GS++
Sbjct: 680 EPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQ 739
Query: 2631 CMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGM 2690
C+CP GFQ C+D++EC + A C N+ G + C P + +G C
Sbjct: 740 CVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVD 799
Query: 2691 GMGRGNP 2697
G P
Sbjct: 800 ECSSGAP 806
Score = 197 bits (502), Expect = 1e-49
Identities = 179/627 (28%), Positives = 244/627 (38%), Gaps = 133/627 (21%)
Query: 55 GPNVCGS----------RYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPS 104
GP +CG+ R C PG++ PGG V CR+ FC +C
Sbjct: 976 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNR---SFCGAHAVCQNLP 1032
Query: 105 GQIAPSC-----GSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG------ 153
G C G+R +HC + C +G CG +CE+
Sbjct: 1033 GSFQCLCDQGYEGARDGRHC---------VDVNECETLQGV----CGAALCENVEGSFLC 1079
Query: 154 -CLNG--------GRCVAPNRCACTYGFTGPQCERDY------------------RTGPC 186
C N GRCV P A T+ + PQ R GP
Sbjct: 1080 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1139
Query: 187 --------FTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPC--EMCPAQPH------- 229
F + C L+ V T CC TVG WG C + CP
Sbjct: 1140 GSGRRECYFDTAAPDACDNILARNV-TWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLC 1198
Query: 230 PCRRGFI-PNIRTGACQDVDECQAIPG-LCQGGNCINTVGSFECKCPAGHKLNEVSQKCE 287
P RG++ P+ +DVDECQ +C+ G C+NT + C C G+ + +C
Sbjct: 1199 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI 1258
Query: 288 DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI-------DVRPGYCYTAL 340
D DEC+ CEGG C NTV SY C C P RC+ D G C+ +
Sbjct: 1259 DNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEV 1318
Query: 341 -TNGRCSN-QLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSV---PMVI 395
+ CS+ +L + T +CCC G W G+ A +CP + ++DF LC+V P
Sbjct: 1319 GADLVCSHPRLDRQATYTECCCLYGEAW--GMDCA--LCPAQDSDDFEALCNVLRPPAYS 1374
Query: 396 PGRP-------EYPPPPLGPIPPVLPVPPGFPPGPQIPV-PRPPVEYLYPSREPPRVLP- 446
P RP EY P LGP LP P P P +P P PP + RE P P
Sbjct: 1375 PPRPGGFGLPYEYGPD-LGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPR 1433
Query: 447 VNVTDY-------------------CQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE 487
++ D+ + R P P + L E
Sbjct: 1434 FDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYE 1493
Query: 488 CIDVDECE-KNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQN---GRICNN 543
++ +EC + C G C+ +TC+C GY+ +TR C DI+EC + +C N
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 544 GRCINTDGSFHCVCNAGFHVTRDGKNC 570
RC+NTDGSF C+C GF T +C
Sbjct: 1554 ARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 186 bits (472), Expect = 3e-46
Identities = 247/943 (26%), Positives = 324/943 (34%), Gaps = 233/943 (24%)
Query: 57 NVCGSRYNAYCCPGWKTLPGGNQCI-VPICRHS---CGDGFCSRPN---MCTCPSGQIAP 109
N GS ++ C G+++ G C V C S C G C C CP G P
Sbjct: 691 NTAGS-FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMG-FQP 748
Query: 110 SCGSRSIQHCNIRCMNGGSCSDDHCL----------CQKGYIGTHCGQPV----CESG-- 153
+ + + C N +C C+ C G+ H G+ C SG
Sbjct: 749 NTAGSECEDVD-ECENHLACPGQECVNSPGSFQCRTCPSGH-HLHRGRCTDVDECSSGAP 806
Query: 154 -CLNGGRCVAPN---RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLC 209
C G C RC+C G+ P R GPC V N+ +G C
Sbjct: 807 PCGPHGHCTNTEGSFRCSCAPGYRAPSG----RPGPCADV--NECLEGDF----CFPHGE 856
Query: 210 CATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSF 269
C ++ C P G+ P R +C DVDEC LCQ G C NT GSF
Sbjct: 857 CLNTDGSFA-----CTCAP-----GYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSF 905
Query: 270 ECKCPAGHKLNEVSQKCEDIDECSTI-PGICEGGECTNTVSSYFC--KCPPGFYTSPDGT 326
EC CP GH+ C D+DEC P +C C N+ SY C C PG++ P+GT
Sbjct: 906 ECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 965
Query: 327 -----RCIDVRPGYC---------------------YTALTNGRCSN------------- 347
C + P C Y G C +
Sbjct: 966 CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAH 1025
Query: 348 ----QLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPM---------- 393
LP S QC CD G G + E +C +
Sbjct: 1026 AVCQNLPGSF---QCLCDQGY---EGARDGRHCVDVNECETLQGVCGAALCENVEGSFLC 1079
Query: 394 VIPGRPE---------YPP----------PPLGPIPPVLPVPPGFPPGPQIP-VPRP-PV 432
V P PE PP P P PVLP P PP P+ P PR PV
Sbjct: 1080 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1139
Query: 433 -----EYLYPSREPP---RVLPVNVT--DYCQLVRYLCQNG-RCIPTPGS------CRCE 475
E + + P +L NVT + C V +G R PG+ C
Sbjct: 1140 GSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1199
Query: 476 CNKGF-----QLDLRGECIDVDECE---KNPCAGGECINNQGSYTCQCRAGYQSTLTRTE 527
+G+ L LR DVDEC+ C G C+N Y+C C GY R E
Sbjct: 1200 HGRGYLAPSGDLSLRR---DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1256
Query: 528 CRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMC 587
C D DEC C GRC+NT GS+HC C + + C + S+ + G+C
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL--GVC 1314
Query: 588 INEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGL 647
E G+ P +L Y EC C+ G D C P A
Sbjct: 1315 WQEVGADLVCSHP--RLDRQATY----TEC----CCLYGEAWGMD----CALCP--AQDS 1358
Query: 648 DGRVCVDTHMRSTCY-----GG----YKRGQCIKPLFGAVTKSECC-------------- 684
D + +R Y GG Y+ G + P + +
Sbjct: 1359 DDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPP 1418
Query: 685 ---CASTEYAFGEPCQPCPAQNS-----AEYQALCSSGPG--MTSAGSDINECALDPDIC 734
A E +G P P E +A GPG D +P+
Sbjct: 1419 PGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEP 1478
Query: 735 PNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPK 794
P G G+Y YE + + C ++ C NG+C P F C C
Sbjct: 1479 PEG------GSYAGSLAEPYE-ELEAEECGILDGCT-------NGRCVRVPEGFTCRCFD 1524
Query: 795 GFIYKPDLKTCEDIDECE----SSP-CINGVCKNSPGSFICEC 832
G+ C DI+EC+ +SP C+N C N+ GSF C C
Sbjct: 1525 GYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCIC 1567
Score = 142 bits (357), Expect = 6e-33
Identities = 82/229 (35%), Positives = 111/229 (48%), Gaps = 22/229 (9%)
Query: 2500 CVNTIGGFTCKCPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFS 2557
C++ G+TC C GF + T CID +EC C + G C+N+PGSF C C GF
Sbjct: 524 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFRCVCGPGFR 582
Query: 2558 LDQTGSSCEDVDECEGNHR----CQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECL 2612
+ C DVDEC HR C G C+N G + C CP GY C D +EC
Sbjct: 583 AGPRAAECLDVDEC---HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 639
Query: 2613 -SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ-DINECGSAQAPCSYG-CSNTEGG 2669
S +CG +C N GS++C+CPAGF+ C+ D++EC PC G C NT G
Sbjct: 640 QSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGS 695
Query: 2670 YLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYEC 2718
+ C CP G+ G G + +P P G ++ E ++C
Sbjct: 696 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT----EGSFQC 740
Score = 74.7 bits (182), Expect = 1e-12
Identities = 33/77 (42%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 572 DMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE----TPGICMNGR 627
+ +EC I + C NG C+ F C C G++L C DINEC+ +C+N R
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1555
Query: 628 CVNTDGSYRCECFPGLA 644
C+NTDGS+RC C PG A
Sbjct: 1556 CLNTDGSFRCICRPGFA 1572
Score = 72.0 bits (175), Expect = 8e-12
Identities = 58/206 (28%), Positives = 92/206 (44%), Gaps = 17/206 (8%)
Query: 2324 ASPNQDECLD-NREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPH-CEICPFQ 2381
++P +D D + GYCF E+ C S T+ CC G WG H C++C +
Sbjct: 236 SAPREDGYSDASGFGYCFRELRGGEC--ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSER 293
Query: 2382 GTVAFKKLCPHG---RGF-MTNGA--DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTP 2435
+ + P G GF NG+ D+DEC C++GEC N RG Y C+C G+
Sbjct: 294 LGNSERVSAPDGPCPTGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLL 352
Query: 2436 DITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHN 2495
D + +SC+ + ++A PC + ++ CS P + + C + + +
Sbjct: 353 DSSRSSCISQHVISEAKGPCFRVLRDG----GCSLPILRNITKQICCCSRVGKAWGR--G 406
Query: 2496 CQFLCVNTIGGFTCKCPPGFTQHHTS 2521
CQ GF CP G H+++
Sbjct: 407 CQLCPPFGSEGFREICPAGPGYHYSA 432
Score = 66.2 bits (160), Expect = 4e-10
Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Query: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQA----PKPCNF 2457
+ +EC ++ D C NG CV + C C GY D+T +CVD+NEC++A P N
Sbjct: 1496 EAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 2458 ICKNTEGSYQCSCPKGYILQEDGRSC 2483
C NT+GS++C C G+ C
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 63.9 bits (154), Expect = 2e-09
Identities = 34/77 (44%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINEC---VLNSLLCDNG 779
+ EC + D C NG C + + C C GY +D T CVDINEC S LC N
Sbjct: 1496 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 780 QCRNTPGSFVCTCPKGF 796
+C NT GSF C C GF
Sbjct: 1555 RCLNTDGSFRCICRPGF 1571
Score = 62.0 bits (149), Expect = 8e-09
Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPG---ICEGG 302
+ +EC + G C G C+ F C+C G++L+ C DI+EC +C
Sbjct: 1496 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP 333
C NT S+ C C PGF + C RP
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1585
Score = 53.1 bits (126), Expect = 4e-06
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 2537 SKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE----GNHRCQHG-CQNIIGGYRCS 2591
+ G C P FTC C G+ LD T +C D++EC+ + C + C N G +RC
Sbjct: 1507 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1566
Query: 2592 CPQGYLQHYQWNQC 2605
C G+ +Q + C
Sbjct: 1567 CRPGFAPTHQPHHC 1580
Score = 52.0 bits (123), Expect = 8e-06
Identities = 22/47 (46%), Positives = 31/47 (65%), Gaps = 4/47 (8%)
Query: 2633 CPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGY 2678
CP GF E+ +G C+D++EC + C +G C+NT GGY C CP G+
Sbjct: 307 CPTGF--ERVNGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGF 350
Score = 52.0 bits (123), Expect = 8e-06
Identities = 28/76 (36%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 2567 DVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAH----ICGGAS 2621
+ +EC C +G C + G+ C C GY CVD NEC A +C A
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1555
Query: 2622 CHNTLGSYKCMCPAGF 2637
C NT GS++C+C GF
Sbjct: 1556 CLNTDGSFRCICRPGF 1571
Score = 51.6 bits (122), Expect = 1e-05
Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 18/109 (16%)
Query: 2494 HNCQFLCVNTIGGFTC------KCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGS 2547
H+CQ LC +G CP GF + + SC D +EC + C G C NT G
Sbjct: 285 HDCQ-LCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATG-GRC-QHGECANTRGG 341
Query: 2548 FTCECQRGFSLDQTGSSC---EDVDECEGNHRCQHGCQNIIGGYRCSCP 2593
+TC C GF LD + SSC + E +G C ++ CS P
Sbjct: 342 YTCVCPDGFLLDSSRSSCISQHVISEAKG------PCFRVLRDGGCSLP 384
Score = 50.4 bits (119), Expect = 2e-05
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 7/100 (7%)
Query: 2565 CEDVDECEGNHRCQHGCQNIIGGYRCS-----CPQGYLQHYQWNQCVDENECLSAHICGG 2619
C G H CQ + + R S CP G+ + C D +EC + C
Sbjct: 275 CRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVN--GSCEDVDECATGGRCQH 332
Query: 2620 ASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPC 2659
C NT G Y C+CP GF + C + A+ PC
Sbjct: 333 GECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 372
Score = 48.5 bits (114), Expect = 9e-05
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Query: 2606 VDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAP----CSY 2661
++ EC C C + C C G++ + C DINEC A+A +
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 2662 GCSNTEGGYLCGCPPGYFRIGQGH 2685
C NT+G + C C PG+ Q H
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTHQPH 1578
Score = 45.1 bits (105), Expect = 0.001
Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 4/81 (4%)
Query: 2443 VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDEC----ATKQHNCQF 2498
++ EC N C + C C GY L +C D++EC A
Sbjct: 1495 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 2499 LCVNTIGGFTCKCPPGFTQHH 2519
C+NT G F C C PGF H
Sbjct: 1555 RCLNTDGSFRCICRPGFAPTH 1575
Score = 40.0 bits (92), Expect = 0.033
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 910 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDI 953
+ +EC + G C NG CV F C+C G LD T C+DI
Sbjct: 1496 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDI 1538
Score = 38.1 bits (87), Expect = 0.13
Identities = 22/50 (44%), Positives = 28/50 (56%), Gaps = 6/50 (12%)
Query: 896 CGKGYSRIKGTQ--CEDIDEC---EVFPGVCKNGLCVNTRGSFKCQCPSG 940
C GY R+ T+ C DI+EC E +C N C+NT GSF+C C G
Sbjct: 1522 CFDGY-RLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1570
Score = 35.4 bits (80), Expect = 0.82
Identities = 14/30 (46%), Positives = 17/30 (56%)
Query: 149 VCESGCLNGGRCVAPNRCACTYGFTGPQCE 178
+C C NGG CV P+RC C F G C+
Sbjct: 115 LCPLICHNGGVCVKPDRCLCPPDFAGKFCQ 144
Score = 34.3 bits (77), Expect = 1.8
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 723 DINEC----ALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 763
DINEC A P +C N C N G+++CIC G+ +C
Sbjct: 1537 DINECDEAEAASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 32.0 bits (71), Expect = 9.0
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 8/61 (13%)
Query: 793 PKGFIYKPDLKTCEDIDECESSPC------INGVCKNSPGSFICECSSESTLDPTKTICI 846
P+G Y L E +E E+ C NG C P F C C LD T+ C+
Sbjct: 1479 PEGGSYAGSL--AEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1536
Query: 847 E 847
+
Sbjct: 1537 D 1537
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 547 bits (1409), Expect = e-155
Identities = 372/1114 (33%), Positives = 488/1114 (43%), Gaps = 153/1114 (13%)
Query: 914 CEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAG 973
C+ P VC G C++ + C C SG L G C+D+ +EC
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDV-----------DEC------ 591
Query: 974 RHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECK 1033
R C+ G CE P C GPGF D++EC
Sbjct: 592 --RRVPPPCAPG------RCENSPGSFR------CVCGPGFRAGPRAAE---CLDVDECH 634
Query: 1034 MIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDF 1093
+P C G+C NT GSF C C +G+ +C D+DEC SP LCGRG C N PG F
Sbjct: 635 RVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSF 694
Query: 1094 ECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISAC 1153
C C G+ D+DEC ++P C G C NT GS+ C CP G + + C
Sbjct: 695 RCVCPAGFRGSACEE----DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 750
Query: 1154 IDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCT 1213
D++EC S C GRC N G +QC C G+ C D+DEC C
Sbjct: 751 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV 810
Query: 1214 NSEGSYEC-SCQPGFALMPDQRSCTDIDECEDNPNICDG-GQCTNIPGEYRCLCYDGFMA 1271
NS GS++C +C G L + CTD+DEC C G CTN G +RC C G+ A
Sbjct: 811 NSPGSFQCRTCPSGHHL--HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 868
Query: 1272 SEDMK-TCVDVNECDLNPNICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIG 1329
C DVNEC L + C G C NT GSF C C GY C D++EC
Sbjct: 869 PSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-- 925
Query: 1330 AHNCGKHAVCTNTAGSFKCSCSPGWIG--DGIKCTDLDEC-SNGTHMCSQHADCKNTMGS 1386
+ + +CTNT GSF+C C PG D C D+DEC G +C C+N+ GS
Sbjct: 926 EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR-CENSPGS 984
Query: 1387 YRCL--CKEGY-TGDGFTCTDLDECSE-NLNLCGNGQCLNAPGGYRCE--CDMGFVPSAD 1440
YRC+ C GY G TC D+DEC E +CG +C N PG YRC CD G+ P+
Sbjct: 985 YRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPG 1044
Query: 1441 GKACEDIDECSLPNIC-VFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCI 1498
G C+D+DEC + C C NLPG F+C C+ GYE R G +C DVNEC C
Sbjct: 1045 G-GCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCG 1103
Query: 1499 SGNCVNTPGSYICDCP--PDFELNPTRVGCVDTRSG-------------NCYLDIRP--- 1540
+ C N GS++C CP P+ E +P CV R+ + L RP
Sbjct: 1104 AALCENVEGSFLCVCPNSPE-EFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPP 1162
Query: 1541 ----------RGDNG--------DTA----CSNEIGVGVSKASCCCSLGKAWGTPC--EM 1576
+G G DTA C N + V+ CCC++G+ WG+ C +
Sbjct: 1163 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ 1222
Query: 1577 CPAVNTSEYKILCPGGEGF-RPNPITVILEDIDECQELPG-LCQGGKCINTFGSFQCRCP 1634
CP T+EY+ LCP G G+ P+ + D+DECQ +C+ G C+NT + C C
Sbjct: 1223 CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCS 1282
Query: 1635 TGYYLNEDTRVCDDVNEC--ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNC----- 1687
GYY + C D +EC E P C G C NTVG+Y C C P + C
Sbjct: 1283 NGYYYHTQRLECIDNDECADEEPA-CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNES 1341
Query: 1688 --MDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFA 1745
+D +C++ AD L T CCC Y G AW C CP +D+F
Sbjct: 1342 QSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLY--GEAWGMDCALCPAQDSDDFE 1399
Query: 1746 TLCGSQRP---------GFVIDI---------YTGLPVDIDECREIPGVCENGVCINMVG 1787
LC RP GF + Y GLP E P + +
Sbjct: 1400 ALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYG-PELYPPPALPYDPYPPPPGP 1458
Query: 1788 SFRCECPVGF-------FYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKP--- 1837
R E P G F +D E GP + +T S+ +P
Sbjct: 1459 FARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEG 1518
Query: 1838 GYRFTSTGQCNDRNECQE--IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC 1895
G S + + E +E I + C++G+C+ F C C G++ + + C+DINEC
Sbjct: 1519 GSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINEC 1578
Query: 1896 ER-----DACGNGTCRNTIGSFNCRCNHGFILSH 1924
+ C N C NT GSF C C GF +H
Sbjct: 1579 DEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1612
Score = 490 bits (1262), Expect = e-138
Identities = 343/1175 (29%), Positives = 483/1175 (41%), Gaps = 263/1175 (22%)
Query: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGT-PCEMCPAVNTSEYKILCP 1590
G C+ ++R G+ C++ + ++ CC G AWG C++C + ++ P
Sbjct: 287 GYCFRELR----GGE--CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP 340
Query: 1591 GGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVN 1650
G CPTG+ + C+DV+
Sbjct: 341 DGP---------------------------------------CPTGFERVNGS--CEDVD 359
Query: 1651 ECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMR-----RSLCYRNYYADNQT 1705
EC T G C G C NT G YTC+CP ++ + ++C+ + C+R +
Sbjct: 360 ECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFR--VLRDGG 417
Query: 1706 CDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDI----YT 1761
C +L N+TK++CCCS +G+AW + C+ CP ++ F +C + PG+ Y
Sbjct: 418 CSLPILRNITKQICCCS-RVGKAWGRGCQLCPPFGSEGFREICPAG-PGYHYSASDLRYN 475
Query: 1762 GLP-------VDIDECREIPGVCENGVCINMVGSFRCEC---------PVGFFYNDKLLV 1805
P V + + R +P + + R E P +
Sbjct: 476 TRPLGQEPPRVSLSQPRTLPATSRPSA--GFLPTHRLEPRPEPRPDPRPGPELPLPSIPA 533
Query: 1806 CEDIDECQNGP---VCQRNAE------CINTAGSYRCDCKPGYRFTSTG-QCNDRNECQE 1855
+ ++GP +CQRN + CI+ Y C C G+R + G +C D +EC+
Sbjct: 534 WTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRR 593
Query: 1856 IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER--DACGNGTCRNTIGSFN 1913
+P C+ G+C ++ GSF C+C GF+ CLD++EC R C G C NT GSF
Sbjct: 594 VPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFL 653
Query: 1914 CRCNHGFILS-HNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCV 1972
C C G+ + H C DVDEC G LC G C N GSF+C C G+ G C
Sbjct: 654 CVCPAGYQAAPHGASCQDVDECTQSPG-LCGRGACKNLPGSFRCVCPAGFR----GSACE 708
Query: 1973 -DINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTC 2029
D++EC EP C PG C N GS+ C CP G+ + C+D+DEC P C G C
Sbjct: 709 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRC 768
Query: 2030 SNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC----------SSPKSRNHS 2079
NTEGSF+C+CP GF +++G C+D+ + G +C + P +
Sbjct: 769 ENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLH 828
Query: 2080 KQECCCALKGEGWGDPCEL---CPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDV 2136
+ C + PC C T + +FR C G G D++EC E D
Sbjct: 829 RGRCTDVDECSSGAPPCGPHGHC-TNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDF 887
Query: 2137 C-KHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVIGGFECTCE 2193
C HG+C+NTDGS+ C C GY G C+D DECS + C +G C N G FEC C
Sbjct: 888 CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICP 947
Query: 2194 EGFEPGP-MMTCEDINECAQN-PLLCAF-RCVNTYGSYEC--KCPVGYVLREDRRMCKDE 2248
G GP + +C D++EC + P LC RC N+ GSY C C GY + C D
Sbjct: 948 PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDV 1006
Query: 2249 DECEE---------------GKHDCTEK---------------------------QMECK 2266
DEC+E G + CT C+
Sbjct: 1007 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQ 1066
Query: 2267 NLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCEC-NDGFTAS 2325
NL G++ C+C GY+ DG CVD NEC+T G+C C N GS+ C C N
Sbjct: 1067 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD 1126
Query: 2326 PNQDECLDNREGYCFTEVLQNMCQ-------------------------IGSSNRN---- 2356
P C+ R Q +GS R
Sbjct: 1127 PMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFD 1186
Query: 2357 -------------PVTKSECCCDGGRGWGPHCEI--CPFQGTVAFKKLCPHGRGFMTNGA 2401
VT ECCC G GWG C I CP T ++ LCPHGRG++
Sbjct: 1187 TAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG 1246
Query: 2402 D------IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC 2455
D +DEC++ D +CK+G
Sbjct: 1247 DLSLRRDVDECQLFRDQ---------------VCKSG----------------------- 1268
Query: 2456 NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPG 2514
+C NT Y C C GY C D DECA ++ C+ CVNT+G + C C P
Sbjct: 1269 --VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1326
Query: 2515 FTQHHTS--CIDNNECTSDINLCGSKGICQNTPGS 2547
+ C+ N + D NL G+C G+
Sbjct: 1327 LVLDGSQRRCVSNESQSLDDNL----GVCWQEVGA 1357
Score = 478 bits (1230), Expect = e-134
Identities = 412/1505 (27%), Positives = 557/1505 (37%), Gaps = 299/1505 (19%)
Query: 958 CFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATK 1017
CF EC P+ G + CC G AWG +C+ C R P GP
Sbjct: 289 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP----- 343
Query: 1018 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 1077
C +GF + +C D+DEC
Sbjct: 344 -------------------------------------CPTGF--ERVNGSCEDVDECATG 364
Query: 1078 PDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG-GVCHNTEGSY 1136
C G+C NT G + C C + GF++ + C ++ G C
Sbjct: 365 -GRCQHGECANTRGGYTCVCPD----GFLLDSSR---SSCISQHVISEAKGPCFRVLRDG 416
Query: 1137 RCECPPGHQLSPNISACIDINEC-ELSAHLCPNGRCVNLIGKYQCACNPGY-HSTPDRLF 1194
C P ++ I C + + LCP + C PGY +S D +
Sbjct: 417 GCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGF--REICPAGPGYHYSASDLRY 474
Query: 1195 C----------VDIDECSIMN-------GGCETFCTNSEGSYECSCQPGFAL-MPDQRSC 1236
V + + + G T +PG L +P +
Sbjct: 475 NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW 534
Query: 1237 T--DIDE-------CEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLN 1287
T +I E C+ NP +C G+C + P Y C C GF S C+DV+EC
Sbjct: 535 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 594
Query: 1288 PNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFK 1347
P C G CEN+ GSF C C G+ C D++EC C C NT GSF
Sbjct: 595 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFL 653
Query: 1348 CSCSPGWIG--DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDL 1405
C C G+ G C D+DEC+ +C + A CKN GS+RC+C G+ G D+
Sbjct: 654 CVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE-EDV 711
Query: 1406 DECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNL 1464
DEC++ CG G+C N G + C C GF G C+D+DEC+ P C +G C N
Sbjct: 712 DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT 771
Query: 1465 PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYIC-DCPPDFELNPTR 1523
G F+C C +G++ + +G C DV+EC + C CVN+PGS+ C CP L+ R
Sbjct: 772 EGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR 831
Query: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS 1583
VD C P G +G C+N G C C+ G
Sbjct: 832 CTDVD----ECSSGAPPCGPHGH--CTNTEG----SFRCSCAPG---------------- 865
Query: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDT 1643
Y+ P G RP P D++EC E G+C+NT GSF C C GY
Sbjct: 866 -YR--APSG---RPGPCA----DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRG 915
Query: 1644 RVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADN 1703
C DV+EC +C G C NT G++ CICPP + +C+D+ +
Sbjct: 916 ASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 975
Query: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGL 1763
Q C+ + C Y+ G P + D
Sbjct: 976 QRCENSPGSYRCVRDCDPGYHAG----------PEGTCD--------------------- 1004
Query: 1764 PVDIDECREI-PGVCENGVCINMVGSFRCE--CPVGFFYNDKLLVCEDIDECQNGPVCQR 1820
D+DEC+E P +C C N GS+RC C G+ C+D+DEC+N C
Sbjct: 1005 --DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGA 1061
Query: 1821 NAECINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTG 1879
+A C N GS++C C GY G+ C D NEC+ + +C C + GSF C+C
Sbjct: 1062 HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNS 1121
Query: 1880 FKTNDDQTMCLDINECERDACGNGTC------------------------------RNTI 1909
+ D T C GT + +
Sbjct: 1122 PEEFDPMT-----GRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1176
Query: 1910 GSFNCRCNHGF--------ILSHNNDCIDVDECA----SGNGNLCRNGQCINT-VGSFQC 1956
GS C IL+ N + EC G G+ CR QC T +Q
Sbjct: 1177 GSGRRECYFDTAAPDACDNILARN---VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQS 1233
Query: 1957 QCNEGYE-VAPDGRTCV--DINEC-LLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK-- 2010
C G +AP G + D++EC L + C G C N Y C C GY ++
Sbjct: 1234 LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1293
Query: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ-------DLRMSYCYA 2063
C D DEC +E C G C NT GS+ C C L S RRC D + C+
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1353
Query: 2064 KFEGGK-CSSPK-SRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC---------- 2111
+ CS P+ R + ECCC L GE WG C LCP + + F +C
Sbjct: 1354 EVGADLVCSHPRLDRQATYTECCC-LYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSP 1412
Query: 2112 --------PYGSGIIVGPDDSAVDMD-ECKEPDVCKHGQCINTDGSY-RCECPFGYILAG 2161
PY G +GP + E P + G + R E P+G
Sbjct: 1413 PRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFD 1472
Query: 2162 NECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMM--------TCEDINECAQN 2213
+ D G P G E PGP T E +
Sbjct: 1473 MPDFEDD----GGPYGES-------------EAPAPPGPGTRWPYRSRDTRRSFPEPEEP 1515
Query: 2214 PLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYM 2273
P GSY Y E C D C G+ C + +
Sbjct: 1516 P---------EGGSYAGSLAEPYEELEAEE-CGILDGCTNGR---------CVRVPEGFT 1556
Query: 2274 CICGPGYQRRPDGEGCVDENEC---QTKPGICENGRCLNTRGSYTCECNDGFTASPNQDE 2330
C C GY+ CVD NEC + +C N RCLNT GS+ C C GF +
Sbjct: 1557 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHH 1616
Query: 2331 CLDNR 2335
C R
Sbjct: 1617 CAPAR 1621
Score = 463 bits (1192), Expect = e-130
Identities = 346/1178 (29%), Positives = 491/1178 (41%), Gaps = 215/1178 (18%)
Query: 531 IDEC-LQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCIN 589
+ +C L + R+ N+ R DG C GF R +CED+DEC+ C +G C N
Sbjct: 321 VHDCQLCSERLGNSERVSAPDGP----CPTGFE--RVNGSCEDVDECATGGRCQHGECAN 374
Query: 590 EDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCECFPGLAVGLD 648
G + C+C GF L S C + E G C V DG C + +
Sbjct: 375 TRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFR---VLRDGG----CSLPILRNIT 427
Query: 649 GRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFG-------------EP 695
++C + + + RG + P FG+ E C A Y + EP
Sbjct: 428 KQICCCSRVGKA----WGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP 483
Query: 696 CQ---------PCPAQNSAEYQAL-------------------------CSSGPGMTSAG 721
+ P ++ SA + +GP + +G
Sbjct: 484 PRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESG 543
Query: 722 SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQC 781
C +P +C G C + Y C C+SG+ + G C+D++EC C G+C
Sbjct: 544 PSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRC 603
Query: 782 RNTPGSFVCTCPKGFIYKPDLKTCEDIDECE--SSPCINGVCKNSPGSFICECSSESTLD 839
N+PGSF C C GF P C D+DEC PC G C+N+PGSF+C C +
Sbjct: 604 ENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAA 663
Query: 840 PTKTICIETIK-----GTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPC-----TL 889
P C + + G C + G C+ N+ G+ +C G GS C
Sbjct: 664 PHGASCQDVDECTQSPGLCGR----GACK-NLPGS---FRCVCPAGFR-GSACEEDVDEC 714
Query: 890 CQVDPICGKG-----------------YSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGS 932
Q P CG G SR G C+D+DEC P C G C NT GS
Sbjct: 715 AQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGS 774
Query: 933 FKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEE 992
F+C CP G + G C D+ L +EC + G+ +
Sbjct: 775 FQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV-----------------NSPGSFQ 817
Query: 993 CEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKM-IPSLCTHGKCRNTIGSF 1051
C CP + + G+ D++EC P HG C NT GSF
Sbjct: 818 CRTCP-----------------SGHHLHRGR--CTDVDECSSGAPPCGPHGHCTNTEGSF 858
Query: 1052 KCRCDSGFALDSEERN-CTDIDECRISPDLC-GRGQCVNTPGDFECKCDEGYESGFMMMK 1109
+C C G+ S C D++EC + D C G+C+NT G F C C GY G
Sbjct: 859 RCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPG-PRGA 916
Query: 1110 NCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINEC-ELSAHLCPN 1168
+C+D+DEC + LC+ G+C NT+GS+ C CPPGH+ P++++C+D++EC E LC +
Sbjct: 917 SCLDVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 975
Query: 1169 GRCVNLIGKYQCA--CNPGYHSTPDRLFCVDIDECSIMNG---GCETFCTNSEGSYEC-- 1221
RC N G Y+C C+PGYH+ P+ C D+DEC G + C N+ GSY C
Sbjct: 976 QRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQR-CENTPGSYRCTP 1033
Query: 1222 SCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDV 1281
+C PG+ P C D+DEC + C N+PG ++CLC G+ + D + CVDV
Sbjct: 1034 ACDPGYQPTPG-GGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 1092
Query: 1282 NECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTN 1341
NEC+ +C + CEN +GSF+C C TG G + +
Sbjct: 1093 NECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPAS 1152
Query: 1342 TAGSFKCSCSP----------GWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGS----Y 1387
+ P G +G G + EC T + C N +
Sbjct: 1153 PVLPARPPPPPLPRRPSTPRQGPVGSGRR-----ECYFDT---AAPDACDNILARNVTWQ 1204
Query: 1388 RCLCKEGYTGDGFTCTDLDEC-----SENLNLCGNGQCLNAPGGYRCECDMGFVPSADGK 1442
C C G G G C + +C +E +LC +G+ GY PS D
Sbjct: 1205 ECCCTVG-EGWGSGCR-IQQCPGTETAEYQSLCPHGR------GY-------LAPSGDLS 1249
Query: 1443 ACEDIDECSL--PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCIS 1499
D+DEC L +C G C N + C C GY C D +EC D C
Sbjct: 1250 LRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG 1309
Query: 1500 GNCVNTPGSYICDCPPDFELNPTRVGCVDTRS-------GNCYLDIRPRGDNGDTACSN- 1551
G CVNT GSY C C P L+ ++ CV S G C+ ++ D CS+
Sbjct: 1310 GRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEV-----GADLVCSHP 1364
Query: 1552 EIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILC 1589
+ + CCC G+AWG C +CPA ++ +++ LC
Sbjct: 1365 RLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC 1402
Score = 451 bits (1159), Expect = e-126
Identities = 329/1091 (30%), Positives = 440/1091 (40%), Gaps = 229/1091 (20%)
Query: 184 GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG-HPCEMCPAQPHPCRRGFIPNIRTG 242
G CF + C L G+ T+ +CC G AWG H C++C + R P
Sbjct: 287 GYCFRELRGGECASPLPGLR-TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP----- 340
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
+ CP G + V+ CED+DEC+T G C+ G
Sbjct: 341 ---------------------------DGPCPTGFE--RVNGSCEDVDECAT-GGRCQHG 370
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVR-----PGYCYTALTNGRCSNQLPQSITKMQ 357
EC NT Y C CP GF + CI G C+ L +G CS + ++ITK
Sbjct: 371 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQI 430
Query: 358 CCCD-AGRCWSPGVTVAPEMCPIRATEDFNKLC--------------------------- 389
CCC G+ W G ++CP +E F ++C
Sbjct: 431 CCCSRVGKAWGRGC----QLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRV 486
Query: 390 --SVPMVIP--GRPE---YPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPP 442
S P +P RP P L P P P P PGP++P+P P + E P
Sbjct: 487 SLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDP---RPGPELPLPSIPA---WTGPEIP 540
Query: 443 RVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRG-ECIDVDECEK--NPC 499
P + CQ +C GRCI P C C+ GF+L +G CIDVDEC + PC
Sbjct: 541 ESGP--SSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC 598
Query: 500 AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNA 559
A G C N+ GS+ C C G+++ EC D+DEC + C+ GRC NT GSF CVC A
Sbjct: 599 APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPA 658
Query: 560 GFHVTRDGKNCEDMDECSI------RNMCLN----------------------------- 584
G+ G +C+D+DEC+ R C N
Sbjct: 659 GYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEP 718
Query: 585 -----GMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCE 638
G C N GSF C C GF+ G C+D++EC +P C GRC NT+GS++C
Sbjct: 719 PPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCV 778
Query: 639 CFPGLAVGLDGRVCVD-----THMR---STCYGGYKRGQCIKPLFGAVTKSECCCASTEY 690
C G G C D H+ C QC G C E
Sbjct: 779 CPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDEC 838
Query: 691 AFG-EPCQPCPAQNSAEYQALCSSGPGMTSAG------SDINECALDPDIC-PNGICENL 742
+ G PC P + E CS PG + +D+NEC L+ D C P+G C N
Sbjct: 839 SSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNT 897
Query: 743 RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDL 802
G++ C C GY G +C+D++EC LC +G C NT GSF C CP G PDL
Sbjct: 898 DGSFACTCAPGYRPGPRGASCLDVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDL 956
Query: 803 KTCEDIDEC-ESSPCINGV--CKNSPGSFIC--ECSSESTLDPTKTICIETIKGTCWQTV 857
+C D+DEC E P + G C+NSPGS+ C +C P T C + + +
Sbjct: 957 ASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPE 1015
Query: 858 IDG--RCEININGATLKSQCCSSLGAAWGSPC---------------TLCQVDP-----I 895
I G RCE C G C +CQ P +
Sbjct: 1016 ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1075
Query: 896 CGKGYSRIK-GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCP-SGMTLDATGRICLDI 953
C +GY + G C D++ECE GVC LC N GSF C CP S D C+
Sbjct: 1076 CDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP 1135
Query: 954 RL--------------------------------------------ETCFLRYEDEECTL 969
R E F + C
Sbjct: 1136 RTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDN 1195
Query: 970 PIAGRHRMDACCCSVGAAWGTE-ECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKD 1028
+A CCC+VG WG+ ++CP T EY+ LCP G G+ + +D
Sbjct: 1196 ILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAP--SGDLSLRRD 1253
Query: 1029 INECKMI-PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
++EC++ +C G C NT + C C +G+ ++ C D DEC C G+CV
Sbjct: 1254 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1313
Query: 1088 NTPGDFECKCD 1098
NT G + C C+
Sbjct: 1314 NTVGSYHCTCE 1324
Score = 424 bits (1090), Expect = e-118
Identities = 309/980 (31%), Positives = 406/980 (41%), Gaps = 172/980 (17%)
Query: 1453 PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTTCISGNCVNTPGSYIC 1511
P +C G C + P + C C+ G+ L G C DV+EC P C G C N+PGS+ C
Sbjct: 553 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRC 612
Query: 1512 DCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWG 1571
C P F P C+D C+ P C LG+
Sbjct: 613 VCGPGFRAGPRAAECLDV--DECHRVPPP-----------------------CDLGRCEN 647
Query: 1572 TPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQC 1631
TP + +CP G ++ P +D+DEC + PGLC G C N GSF+C
Sbjct: 648 TP---------GSFLCVCPAG--YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRC 696
Query: 1632 RCPTGYYLNEDTRVCDDVNEC-ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
CP G+ + +DV+EC + P CGPG C NT G++ C CP + G C D+
Sbjct: 697 VCPAGF---RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDV 753
Query: 1691 RRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCE-QCPIPSTDEFATLCG 1749
C R+ C+Y GR N QC P
Sbjct: 754 DE--CARSPPP-------------------CTY--GRCENTEGSFQCVCPM--------- 781
Query: 1750 SQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCE-CPVGFFYNDKLLVCED 1808
GF + D+DEC E C C+N GSF+C CP G + C D
Sbjct: 782 ----GFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR--CTD 834
Query: 1809 IDECQNG-PVCQRNAECINTAGSYRCDCKPGYRFTS--TGQCNDRNECQEIPNICSHGQC 1865
+DEC +G P C + C NT GS+RC C PGYR S G C D NEC E HG+C
Sbjct: 835 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGEC 894
Query: 1866 IDTVGSFYCLCHTGFKTNDDQTMCLDINEC-ERDACGNGTCRNTIGSFNCRCNHGFILSH 1924
++T GSF C C G++ CLD++EC E D C +G C NT GSF C C G
Sbjct: 895 LNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 954
Query: 1925 N-NDCIDVDECASGNGNLCRNGQCINTVGSFQC--QCNEGYEVAPDGRTCVDINECL-LE 1980
+ C+DVDEC LC + +C N+ GS++C C+ GY P+G TC D++EC
Sbjct: 955 DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYG 1013
Query: 1981 PRKCAPGTCQNLDGSYRCI--CPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFK 2037
P C C+N GSYRC C PGY C+D+DEC A C N GSF+
Sbjct: 1014 PEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1073
Query: 2038 CLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCE 2097
CLC +G+ + GR C D+ G C + N C
Sbjct: 1074 CLCDQGYEGARDGRHCVDVNECETLQ----GVCGAALCENVEGSFLC------------- 1116
Query: 2098 LCPTEPDE----AFRQICPYGS-GIIVGPDDSAVDMDEC----------KEPDVCKHGQC 2142
+CP P+E R + P S G G A + P + G
Sbjct: 1117 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1176
Query: 2143 INTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCE--EGFEPGP 2200
GS R EC F + + + C N +NV EC C EG+ G
Sbjct: 1177 ----GSGRRECYF-------------DTAAPDACDNILARNVTWQ-ECCCTVGEGWGSG- 1217
Query: 2201 MMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVG--YVLRE-DRRMCKDEDECEEGKHD 2257
C I +C Y+ CP G Y+ D + +D DEC+ + D
Sbjct: 1218 ---CR-IQQCPGTET----------AEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFR-D 1262
Query: 2258 CTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCE 2317
K C N Y C C GY C+D +EC + CE GRC+NT GSY C
Sbjct: 1263 QVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCT 1322
Query: 2318 CNDGFTASPNQDEC-------LDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRG 2370
C +Q C LD+ G C+ EV ++ T +ECCC G
Sbjct: 1323 CEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEA 1382
Query: 2371 WGPHCEICPFQGTVAFKKLC 2390
WG C +CP Q + F+ LC
Sbjct: 1383 WGMDCALCPAQDSDDFEALC 1402
Score = 379 bits (973), Expect = e-104
Identities = 274/839 (32%), Positives = 357/839 (42%), Gaps = 140/839 (16%)
Query: 1938 NGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYR 1997
N +C G+CI+ + C C+ G+ ++P G C+D++EC P CAPG C+N GS+R
Sbjct: 552 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 611
Query: 1998 CICPPGYSL--QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQD 2055
C+C PG+ + +C D+DEC P C LG C NT GSF C+CP G+ + G CQD
Sbjct: 612 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 671
Query: 2056 LRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGS 2115
+ +C+ L G G C P +FR +CP G
Sbjct: 672 V-----------DECTQSPG-----------LCGRG------ACKNLPG-SFRCVCPAG- 701
Query: 2116 GIIVGPDDSAVDMDEC-KEPDVCKHGQCINTDGSYRCECPFGYILAGN--ECVDTDECSV 2172
D+DEC +EP C G+C NT GS+ C CP G+ G C D DEC+
Sbjct: 702 ---FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECAR 758
Query: 2173 GNP-CGNGTCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQNPLLCAFR-CVNTYGSYE 2229
P C G C+N G F+C C GF+P + CED++EC +N L C + CVN+ GS++
Sbjct: 759 SPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQ 817
Query: 2230 CK-CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG 2288
C+ CP G+ L R C D DEC G C C N G++ C C PGY R P G
Sbjct: 818 CRTCPSGHHLHRGR--CTDVDECSSGAPPCGPHG-HCTNTEGSFRCSCAPGY-RAPSGRP 873
Query: 2289 --CVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQN 2346
C D NEC +G CLNT GS+ C C G+ P CLD E C E +
Sbjct: 874 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE--CSEE---D 928
Query: 2347 MCQIGSSNRNPVTKSECCCDGGRGWGP----------------------HCEICPFQGTV 2384
+CQ G N EC C G GP CE P G+
Sbjct: 929 LCQSGICT-NTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP--GSY 985
Query: 2385 AFKKLCPHGRGFMTNGA--DIDECKVIH-DVCRNGECVNDRGSYHCI--CKTGYTPDITG 2439
+ C G G D+DEC+ ++C C N GSY C C GY P G
Sbjct: 986 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PG 1044
Query: 2440 TSCVDLNEC-NQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC-Q 2497
C D++EC N++ + +C+N GS+QC C +GY DGR C D++EC T Q C
Sbjct: 1045 GGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGA 1104
Query: 2498 FLCVNTIGGFTCKC---PPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQ- 2553
LC N G F C C P F C+ TS GS+ P S +
Sbjct: 1105 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR--TSAGTFPGSQ---PQAPASPVLPARP 1159
Query: 2554 ------RGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGG-------------------- 2587
R S + G EC + C NI+
Sbjct: 1160 PPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR 1219
Query: 2588 -----------YRCSCP--QGYLQ---HYQWNQCVDENECLSAHICGGASCHNTLGSYKC 2631
Y+ CP +GYL + VDE + +C C NT Y C
Sbjct: 1220 IQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC 1279
Query: 2632 MCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGC-PPGYFRIGQGHCVS 2688
C G+ Y C D +EC + C G C NT G Y C C PP Q CVS
Sbjct: 1280 YCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1338
Score = 367 bits (943), Expect = e-101
Identities = 274/930 (29%), Positives = 378/930 (40%), Gaps = 154/930 (16%)
Query: 172 FTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPC 231
+TGP+ +GP S+ MCQ VC C + R G+ C C
Sbjct: 534 WTGPEIPE---SGP-----SSGMCQRNPQ--VCGPGRC---ISRPSGYTCA--------C 572
Query: 232 RRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDE 291
GF + + C DVDEC+ +P C G C N+ GSF C C G + + +C D+DE
Sbjct: 573 DSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE 632
Query: 292 CSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV-----RPGYCYTALTNGRCS 346
C +P C+ G C NT S+ C CP G+ +P G C DV PG C G C
Sbjct: 633 CHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLC----GRGACK 688
Query: 347 NQLPQSITKMQCCCDAG----RCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPG--RPE 400
N LP S +C C AG C A E P N S P R
Sbjct: 689 N-LPGS---FRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 744
Query: 401 YPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYL- 459
P P + PP G + + + P P D + +L
Sbjct: 745 GPGAPCQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLA 803
Query: 460 CQNGRCIPTPGSCRCE-CNKGFQLDLRGECIDVDECEKN--PCA-GGECINNQGSYTCQC 515
C C+ +PGS +C C G L RG C DVDEC PC G C N +GS+ C C
Sbjct: 804 CPGQECVNSPGSFQCRTCPSGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 862
Query: 516 RAGYQSTLTRT-ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMD 574
GY++ R C D++ECL+ +G C+NTDGSF C C G+ G +C D+D
Sbjct: 863 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 922
Query: 575 ECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET--PGICMNGRCVNTD 632
ECS ++C +G+C N DGSF+CIC PG + D C D++EC P +C + RC N+
Sbjct: 923 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP 982
Query: 633 GSYRC--ECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEY 690
GSYRC +C PG G +G C D EC E
Sbjct: 983 GSYRCVRDCDPGYHAGPEG-TCDDV-------------------------DECQEYGPEI 1016
Query: 691 AFGEPCQPCPAQNSAEYQALCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKC 748
+ C+ P S C G T G D++EC + +C+NL G+++C
Sbjct: 1017 CGAQRCENTP--GSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC 1074
Query: 749 ICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDI 808
+C+ GYE G++CVD+NEC +C C N GSF+C CP + D T +
Sbjct: 1075 LCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNS-PEEFDPMTGRCV 1133
Query: 809 DECESSPCINGVCKNSPGSFICECSSESTLDPTKTIC-----IETIKGTCW-QTVIDGRC 862
S+ G +P S + P + + + + C+ T C
Sbjct: 1134 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDAC 1193
Query: 863 EININGATLKSQCCSSLGAAWGSPCTL--------------------------------- 889
+ + +CC ++G WGS C +
Sbjct: 1194 DNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRD 1253
Query: 890 ---CQV--DPICGKG-----------------YSRIKGTQCEDIDECEVFPGVCKNGLCV 927
CQ+ D +C G Y + +C D DEC C+ G CV
Sbjct: 1254 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1313
Query: 928 NTRGSFKCQCPSGMTLDATGRIC-------LDIRLETCFLRY-EDEECTLPIAGRH-RMD 978
NT GS+ C C + LD + R C LD L C+ D C+ P R
Sbjct: 1314 NTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYT 1373
Query: 979 ACCCSVGAAWGTEECEECPMRNTPEYEELC 1008
CCC G AWG +C CP +++ ++E LC
Sbjct: 1374 ECCCLYGEAWGM-DCALCPAQDSDDFEALC 1402
Score = 351 bits (901), Expect = 5e-96
Identities = 272/815 (33%), Positives = 362/815 (44%), Gaps = 85/815 (10%)
Query: 1925 NNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC 1984
N C DVDECA+G C++G+C NT G + C C +G+ + +C+ + E
Sbjct: 352 NGSCEDVDECATGGR--CQHGECANTRGGYTCVCPDGFLLDSSRSSCIS-QHVISE---- 404
Query: 1985 APGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2044
A G C + C P ++ + C C L +EG F+ +CP G
Sbjct: 405 AKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG-FREICPAGP 463
Query: 2045 SLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPT--- 2101
S DLR + E + S + R + G+ L P
Sbjct: 464 GYHYSA---SDLRYNTRPLGQEPPRVSLSQPRTLP----ATSRPSAGFLPTHRLEPRPEP 516
Query: 2102 EPDEAFRQICPYGS-GIIVGPD--DSAVDMDEC-KEPDVCKHGQCINTDGSYRCECPFGY 2157
PD P S GP+ +S C + P VC G+CI+ Y C C G+
Sbjct: 517 RPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGF 576
Query: 2158 ILA--GNECVDTDECS-VGNPCGNGTCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQN 2213
L+ G C+D DEC V PC G C+N G F C C GF GP C D++EC +
Sbjct: 577 RLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 636
Query: 2214 PLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTY 2272
P C RC NT GS+ C CP GY C+D DEC + C CKNL G++
Sbjct: 637 PPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA--CKNLPGSF 694
Query: 2273 MCICGPGYQRRPDGEGCVDE-NECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDEC 2331
C+C G++ G C ++ +EC +P C GRC NT GS+ C C GF + C
Sbjct: 695 RCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 750
Query: 2332 LDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGG---RGWGPHCE---------ICP 2379
D E C C G N +C C G G CE CP
Sbjct: 751 QDVDE--CARS--PPPCTYGRCE-NTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP 805
Query: 2380 FQGTV----AFK-KLCPHG----RGFMTNGADIDECKVIHDVCR-NGECVNDRGSYHCIC 2429
Q V +F+ + CP G RG T D+DEC C +G C N GS+ C C
Sbjct: 806 GQECVNSPGSFQCRTCPSGHHLHRGRCT---DVDECSSGAPPCGPHGHCTNTEGSFRCSC 862
Query: 2430 KTGY-TPDITGTSCVDLNECNQAPKPC--NFICKNTEGSYQCSCPKGYILQEDGRSCKDL 2486
GY P C D+NEC + C + C NT+GS+ C+C GY G SC D+
Sbjct: 863 APGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDV 921
Query: 2487 DECATKQHNCQFLCVNTIGGFTCKCPPGFTQHH--TSCIDNNECTS-DINLCGSKGICQN 2543
DEC+ + +C NT G F C CPPG SC+D +EC LCGS+ C+N
Sbjct: 922 DECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR-CEN 980
Query: 2544 TPGSFTC--ECQRGFSLDQTGSSCEDVDECE--GNHRC-QHGCQNIIGGYRCS--CPQGY 2596
+PGS+ C +C G+ G+ C+DVDEC+ G C C+N G YRC+ C GY
Sbjct: 981 SPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY 1039
Query: 2597 LQHYQWNQCVDENECLSAHICGG-ASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSA 2655
Q C D +EC + CG A C N GS++C+C G++ + C D+NEC +
Sbjct: 1040 -QPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETL 1098
Query: 2656 QAPCSYG-CSNTEGGYLCGCP--PGYFRIGQGHCV 2687
Q C C N EG +LC CP P F G CV
Sbjct: 1099 QGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1133
Score = 311 bits (796), Expect = 8e-84
Identities = 279/970 (28%), Positives = 371/970 (38%), Gaps = 270/970 (27%)
Query: 55 GPNVCGSRYNAYCCP---GWKTLPGGNQCI-VPICRHS-------------------CGD 91
GP C SR + Y C G++ P G +CI V CR CG
Sbjct: 557 GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGP 616
Query: 92 GFCSRPNMCTC----PSGQIAPSCGSRSIQHC--NIRCM---------NGGSCSD-DHCL 135
GF + P C ++ P C ++ + C+ +G SC D D C
Sbjct: 617 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 676
Query: 136 CQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERD-----YRTGPCFTVI 190
G CG+ C++ L G RC C GF G CE D PC
Sbjct: 677 QSPGL----CGRGACKN--LPGSF-----RCVCPAGFRGSACEEDVDECAQEPPPC---- 721
Query: 191 SNQMCQGQLSGIVCTKTLCCATV-GRAWGHPC---EMCPAQPHPCR-------------- 232
C C C A R G PC + C P PC
Sbjct: 722 GPGRCDNTAGSFHCA---CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCV 778
Query: 233 --RGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECK-CPAGHKLNEVSQKCEDI 289
GF PN C+DVDEC+ C G C+N+ GSF+C+ CP+GH L+ +C D+
Sbjct: 779 CPMGFQPNTAGSECEDVDECENHLA-CPGQECVNSPGSFQCRTCPSGHHLHR--GRCTDV 835
Query: 290 DECST-IPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQ 348
DECS+ P G CTNT S+ C C PG Y +P G RPG C
Sbjct: 836 DECSSGAPPCGPHGHCTNTEGSFRCSCAPG-YRAPSG------RPGPC------------ 876
Query: 349 LPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGP 408
+ C + C+ G + F C+
Sbjct: 877 -----ADVNECLEGDFCFPHGEC-------LNTDGSFACTCA------------------ 906
Query: 409 IPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPT 468
PG+ PGP+ V + D CQ +G C T
Sbjct: 907 --------PGYRPGPR-------------GASCLDVDECSEEDLCQ-------SGICTNT 938
Query: 469 PGSCRCECNKGFQL--DLRGECIDVDEC-EKNP--CAGGECINNQGSYTC--QCRAGYQS 521
GS C C G + DL C+DVDEC E+ P C C N+ GSY C C GY +
Sbjct: 939 DGSFECICPPGHRAGPDL-ASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA 997
Query: 522 TLTRTECRDIDECLQNG-RICNNGRCINTDGSFHC--VCNAGFHVTRDGKNCEDMDECSI 578
T C D+DEC + G IC RC NT GS+ C C+ G+ T G C+D+DEC
Sbjct: 998 GPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PGGGCQDVDECRN 1055
Query: 579 RNMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYR 636
R+ C + +C N GSF+C+C G++ A DGR+C D+NECET G+C C N +GS+
Sbjct: 1056 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1115
Query: 637 CEC--FPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGA----------------- 677
C C P + GR CV + + G + P+ A
Sbjct: 1116 CVCPNSPEEFDPMTGR-CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQG 1174
Query: 678 --------------------------VTKSECCCASTEYAFGEPC--QPCPAQNSAEYQA 709
VT ECCC E +G C Q CP +AEYQ+
Sbjct: 1175 PVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGE-GWGSGCRIQQCPGTETAEYQS 1233
Query: 710 LCSSGPGM------TSAGSDINECALDPD-ICPNGICENLRGTYKCICNSGYEVDSTGKN 762
LC G G S D++EC L D +C +G+C N Y C C++GY +
Sbjct: 1234 LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1293
Query: 763 CVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCK 822
C+D +EC C+ G+C NT GS+ CTC + + C
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC----------------- 1336
Query: 823 NSPGSFICECSSESTLDPTKTICIETIKGTCWQTV-IDGRC-EININGATLKSQCCSSLG 880
S+ES ++ G CWQ V D C ++ ++CC G
Sbjct: 1337 ---------VSNESQ-------SLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYG 1380
Query: 881 AAWGSPCTLC 890
AWG C LC
Sbjct: 1381 EAWGMDCALC 1390
Score = 202 bits (514), Expect = 4e-51
Identities = 111/307 (36%), Positives = 148/307 (48%), Gaps = 13/307 (4%)
Query: 2399 NGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN-F 2457
+G C+ VC G C++ Y C C +G+ GT C+D++EC + P PC
Sbjct: 542 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG 601
Query: 2458 ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPGF- 2515
C+N+ GS++C C G+ C D+DEC C C NT G F C CP G+
Sbjct: 602 RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 661
Query: 2516 -TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDEC-E 2572
H SC D +ECT LCG +G C+N PGSF C C GF GS+CE DVDEC +
Sbjct: 662 AAPHGASCQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQ 716
Query: 2573 GNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHNTLGSYK 2630
C G C N G + C+CP G+ C D +EC S C C NT GS++
Sbjct: 717 EPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQ 776
Query: 2631 CMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGM 2690
C+CP GFQ C+D++EC + A C N+ G + C P + +G C
Sbjct: 777 CVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVD 836
Query: 2691 GMGRGNP 2697
G P
Sbjct: 837 ECSSGAP 843
Score = 197 bits (502), Expect = 1e-49
Identities = 179/627 (28%), Positives = 244/627 (38%), Gaps = 133/627 (21%)
Query: 55 GPNVCGS----------RYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPS 104
GP +CG+ R C PG++ PGG V CR+ FC +C
Sbjct: 1013 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNR---SFCGAHAVCQNLP 1069
Query: 105 GQIAPSC-----GSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG------ 153
G C G+R +HC + C +G CG +CE+
Sbjct: 1070 GSFQCLCDQGYEGARDGRHC---------VDVNECETLQGV----CGAALCENVEGSFLC 1116
Query: 154 -CLNG--------GRCVAPNRCACTYGFTGPQCERDY------------------RTGPC 186
C N GRCV P A T+ + PQ R GP
Sbjct: 1117 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1176
Query: 187 --------FTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPC--EMCPAQPH------- 229
F + C L+ V T CC TVG WG C + CP
Sbjct: 1177 GSGRRECYFDTAAPDACDNILARNV-TWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLC 1235
Query: 230 PCRRGFI-PNIRTGACQDVDECQAIPG-LCQGGNCINTVGSFECKCPAGHKLNEVSQKCE 287
P RG++ P+ +DVDECQ +C+ G C+NT + C C G+ + +C
Sbjct: 1236 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI 1295
Query: 288 DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI-------DVRPGYCYTAL 340
D DEC+ CEGG C NTV SY C C P RC+ D G C+ +
Sbjct: 1296 DNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEV 1355
Query: 341 -TNGRCSN-QLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSV---PMVI 395
+ CS+ +L + T +CCC G W G+ A +CP + ++DF LC+V P
Sbjct: 1356 GADLVCSHPRLDRQATYTECCCLYGEAW--GMDCA--LCPAQDSDDFEALCNVLRPPAYS 1411
Query: 396 PGRP-------EYPPPPLGPIPPVLPVPPGFPPGPQIPV-PRPPVEYLYPSREPPRVLP- 446
P RP EY P LGP LP P P P +P P PP + RE P P
Sbjct: 1412 PPRPGGFGLPYEYGPD-LGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPR 1470
Query: 447 VNVTDY-------------------CQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE 487
++ D+ + R P P + L E
Sbjct: 1471 FDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYE 1530
Query: 488 CIDVDECE-KNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQN---GRICNN 543
++ +EC + C G C+ +TC+C GY+ +TR C DI+EC + +C N
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 544 GRCINTDGSFHCVCNAGFHVTRDGKNC 570
RC+NTDGSF C+C GF T +C
Sbjct: 1591 ARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 186 bits (472), Expect = 3e-46
Identities = 247/943 (26%), Positives = 324/943 (34%), Gaps = 233/943 (24%)
Query: 57 NVCGSRYNAYCCPGWKTLPGGNQCI-VPICRHS---CGDGFCSRPN---MCTCPSGQIAP 109
N GS ++ C G+++ G C V C S C G C C CP G P
Sbjct: 728 NTAGS-FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMG-FQP 785
Query: 110 SCGSRSIQHCNIRCMNGGSCSDDHCL----------CQKGYIGTHCGQPV----CESG-- 153
+ + + C N +C C+ C G+ H G+ C SG
Sbjct: 786 NTAGSECEDVD-ECENHLACPGQECVNSPGSFQCRTCPSGH-HLHRGRCTDVDECSSGAP 843
Query: 154 -CLNGGRCVAPN---RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLC 209
C G C RC+C G+ P R GPC V N+ +G C
Sbjct: 844 PCGPHGHCTNTEGSFRCSCAPGYRAPSG----RPGPCADV--NECLEGDF----CFPHGE 893
Query: 210 CATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSF 269
C ++ C P G+ P R +C DVDEC LCQ G C NT GSF
Sbjct: 894 CLNTDGSFA-----CTCAP-----GYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSF 942
Query: 270 ECKCPAGHKLNEVSQKCEDIDECSTI-PGICEGGECTNTVSSYFC--KCPPGFYTSPDGT 326
EC CP GH+ C D+DEC P +C C N+ SY C C PG++ P+GT
Sbjct: 943 ECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT 1002
Query: 327 -----RCIDVRPGYC---------------------YTALTNGRCSN------------- 347
C + P C Y G C +
Sbjct: 1003 CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAH 1062
Query: 348 ----QLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPM---------- 393
LP S QC CD G G + E +C +
Sbjct: 1063 AVCQNLPGSF---QCLCDQGY---EGARDGRHCVDVNECETLQGVCGAALCENVEGSFLC 1116
Query: 394 VIPGRPE---------YPP----------PPLGPIPPVLPVPPGFPPGPQIP-VPRP-PV 432
V P PE PP P P PVLP P PP P+ P PR PV
Sbjct: 1117 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1176
Query: 433 -----EYLYPSREPP---RVLPVNVT--DYCQLVRYLCQNG-RCIPTPGS------CRCE 475
E + + P +L NVT + C V +G R PG+ C
Sbjct: 1177 GSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1236
Query: 476 CNKGF-----QLDLRGECIDVDECE---KNPCAGGECINNQGSYTCQCRAGYQSTLTRTE 527
+G+ L LR DVDEC+ C G C+N Y+C C GY R E
Sbjct: 1237 HGRGYLAPSGDLSLRR---DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1293
Query: 528 CRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMC 587
C D DEC C GRC+NT GS+HC C + + C + S+ + G+C
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL--GVC 1351
Query: 588 INEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGL 647
E G+ P +L Y EC C+ G D C P A
Sbjct: 1352 WQEVGADLVCSHP--RLDRQATY----TEC----CCLYGEAWGMD----CALCP--AQDS 1395
Query: 648 DGRVCVDTHMRSTCY-----GG----YKRGQCIKPLFGAVTKSECC-------------- 684
D + +R Y GG Y+ G + P + +
Sbjct: 1396 DDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPP 1455
Query: 685 ---CASTEYAFGEPCQPCPAQNS-----AEYQALCSSGPG--MTSAGSDINECALDPDIC 734
A E +G P P E +A GPG D +P+
Sbjct: 1456 PGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEP 1515
Query: 735 PNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPK 794
P G G+Y YE + + C ++ C NG+C P F C C
Sbjct: 1516 PEG------GSYAGSLAEPYE-ELEAEECGILDGCT-------NGRCVRVPEGFTCRCFD 1561
Query: 795 GFIYKPDLKTCEDIDECE----SSP-CINGVCKNSPGSFICEC 832
G+ C DI+EC+ +SP C+N C N+ GSF C C
Sbjct: 1562 GYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCIC 1604
Score = 142 bits (357), Expect = 6e-33
Identities = 82/229 (35%), Positives = 111/229 (48%), Gaps = 22/229 (9%)
Query: 2500 CVNTIGGFTCKCPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFS 2557
C++ G+TC C GF + T CID +EC C + G C+N+PGSF C C GF
Sbjct: 561 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFRCVCGPGFR 619
Query: 2558 LDQTGSSCEDVDECEGNHR----CQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECL 2612
+ C DVDEC HR C G C+N G + C CP GY C D +EC
Sbjct: 620 AGPRAAECLDVDEC---HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 676
Query: 2613 -SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ-DINECGSAQAPCSYG-CSNTEGG 2669
S +CG +C N GS++C+CPAGF+ C+ D++EC PC G C NT G
Sbjct: 677 QSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGS 732
Query: 2670 YLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYEC 2718
+ C CP G+ G G + +P P G ++ E ++C
Sbjct: 733 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT----EGSFQC 777
Score = 74.7 bits (182), Expect = 1e-12
Identities = 33/77 (42%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 572 DMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE----TPGICMNGR 627
+ +EC I + C NG C+ F C C G++L C DINEC+ +C+N R
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1592
Query: 628 CVNTDGSYRCECFPGLA 644
C+NTDGS+RC C PG A
Sbjct: 1593 CLNTDGSFRCICRPGFA 1609
Score = 72.0 bits (175), Expect = 8e-12
Identities = 58/206 (28%), Positives = 92/206 (44%), Gaps = 17/206 (8%)
Query: 2324 ASPNQDECLD-NREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPH-CEICPFQ 2381
++P +D D + GYCF E+ C S T+ CC G WG H C++C +
Sbjct: 273 SAPREDGYSDASGFGYCFRELRGGEC--ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSER 330
Query: 2382 GTVAFKKLCPHG---RGF-MTNGA--DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTP 2435
+ + P G GF NG+ D+DEC C++GEC N RG Y C+C G+
Sbjct: 331 LGNSERVSAPDGPCPTGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLL 389
Query: 2436 DITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHN 2495
D + +SC+ + ++A PC + ++ CS P + + C + + +
Sbjct: 390 DSSRSSCISQHVISEAKGPCFRVLRDG----GCSLPILRNITKQICCCSRVGKAWGR--G 443
Query: 2496 CQFLCVNTIGGFTCKCPPGFTQHHTS 2521
CQ GF CP G H+++
Sbjct: 444 CQLCPPFGSEGFREICPAGPGYHYSA 469
Score = 66.2 bits (160), Expect = 4e-10
Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Query: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQA----PKPCNF 2457
+ +EC ++ D C NG CV + C C GY D+T +CVD+NEC++A P N
Sbjct: 1533 EAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 2458 ICKNTEGSYQCSCPKGYILQEDGRSC 2483
C NT+GS++C C G+ C
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 63.9 bits (154), Expect = 2e-09
Identities = 34/77 (44%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINEC---VLNSLLCDNG 779
+ EC + D C NG C + + C C GY +D T CVDINEC S LC N
Sbjct: 1533 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 780 QCRNTPGSFVCTCPKGF 796
+C NT GSF C C GF
Sbjct: 1592 RCLNTDGSFRCICRPGF 1608
Score = 62.0 bits (149), Expect = 8e-09
Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPG---ICEGG 302
+ +EC + G C G C+ F C+C G++L+ C DI+EC +C
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP 333
C NT S+ C C PGF + C RP
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1622
Score = 53.1 bits (126), Expect = 4e-06
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 2537 SKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE----GNHRCQHG-CQNIIGGYRCS 2591
+ G C P FTC C G+ LD T +C D++EC+ + C + C N G +RC
Sbjct: 1544 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1603
Query: 2592 CPQGYLQHYQWNQC 2605
C G+ +Q + C
Sbjct: 1604 CRPGFAPTHQPHHC 1617
Score = 52.0 bits (123), Expect = 8e-06
Identities = 22/47 (46%), Positives = 31/47 (65%), Gaps = 4/47 (8%)
Query: 2633 CPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGY 2678
CP GF E+ +G C+D++EC + C +G C+NT GGY C CP G+
Sbjct: 344 CPTGF--ERVNGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGF 387
Score = 52.0 bits (123), Expect = 8e-06
Identities = 28/76 (36%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 2567 DVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAH----ICGGAS 2621
+ +EC C +G C + G+ C C GY CVD NEC A +C A
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1592
Query: 2622 CHNTLGSYKCMCPAGF 2637
C NT GS++C+C GF
Sbjct: 1593 CLNTDGSFRCICRPGF 1608
Score = 51.6 bits (122), Expect = 1e-05
Identities = 37/109 (33%), Positives = 49/109 (44%), Gaps = 18/109 (16%)
Query: 2494 HNCQFLCVNTIGGFTC------KCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGS 2547
H+CQ LC +G CP GF + + SC D +EC + C G C NT G
Sbjct: 322 HDCQ-LCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATG-GRC-QHGECANTRGG 378
Query: 2548 FTCECQRGFSLDQTGSSC---EDVDECEGNHRCQHGCQNIIGGYRCSCP 2593
+TC C GF LD + SSC + E +G C ++ CS P
Sbjct: 379 YTCVCPDGFLLDSSRSSCISQHVISEAKG------PCFRVLRDGGCSLP 421
Score = 50.4 bits (119), Expect = 2e-05
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 7/100 (7%)
Query: 2565 CEDVDECEGNHRCQHGCQNIIGGYRCS-----CPQGYLQHYQWNQCVDENECLSAHICGG 2619
C G H CQ + + R S CP G+ + C D +EC + C
Sbjct: 312 CRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVN--GSCEDVDECATGGRCQH 369
Query: 2620 ASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPC 2659
C NT G Y C+CP GF + C + A+ PC
Sbjct: 370 GECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 409
Score = 48.5 bits (114), Expect = 9e-05
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Query: 2606 VDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAP----CSY 2661
++ EC C C + C C G++ + C DINEC A+A +
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 2662 GCSNTEGGYLCGCPPGYFRIGQGH 2685
C NT+G + C C PG+ Q H
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTHQPH 1615
Score = 45.1 bits (105), Expect = 0.001
Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 4/81 (4%)
Query: 2443 VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDEC----ATKQHNCQF 2498
++ EC N C + C C GY L +C D++EC A
Sbjct: 1532 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 2499 LCVNTIGGFTCKCPPGFTQHH 2519
C+NT G F C C PGF H
Sbjct: 1592 RCLNTDGSFRCICRPGFAPTH 1612
Score = 40.0 bits (92), Expect = 0.033
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 910 DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDI 953
+ +EC + G C NG CV F C+C G LD T C+DI
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDI 1575
Score = 38.1 bits (87), Expect = 0.13
Identities = 22/50 (44%), Positives = 28/50 (56%), Gaps = 6/50 (12%)
Query: 896 CGKGYSRIKGTQ--CEDIDEC---EVFPGVCKNGLCVNTRGSFKCQCPSG 940
C GY R+ T+ C DI+EC E +C N C+NT GSF+C C G
Sbjct: 1559 CFDGY-RLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1607
Score = 37.4 bits (85), Expect = 0.22
Identities = 36/133 (27%), Positives = 53/133 (39%), Gaps = 27/133 (20%)
Query: 67 CCPGWKTLPGGNQCIVPICR-HSCGDGFCSRPNMCTCPSGQI---APSCGSRSIQHCNIR 122
CCPG + ++CI CR SC C+ P C P + +PS R + N +
Sbjct: 55 CCPGQTSRR--SRCIRAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVS-LNWQ 111
Query: 123 CMNGGSCSDDHCLCQK------GYIGTHCGQP-----------VCESGCLNGGRCVAPNR 165
+ + + L ++ G G +P +C C NGG CV P+R
Sbjct: 112 PL---TLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDR 168
Query: 166 CACTYGFTGPQCE 178
C C F G C+
Sbjct: 169 CLCPPDFAGKFCQ 181
Score = 34.3 bits (77), Expect = 1.8
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 723 DINEC----ALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 763
DINEC A P +C N C N G+++CIC G+ +C
Sbjct: 1574 DINECDEAEAASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 32.0 bits (71), Expect = 9.0
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 8/61 (13%)
Query: 793 PKGFIYKPDLKTCEDIDECESSPC------INGVCKNSPGSFICECSSESTLDPTKTICI 846
P+G Y L E +E E+ C NG C P F C C LD T+ C+
Sbjct: 1516 PEGGSYAGSL--AEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1573
Query: 847 E 847
+
Sbjct: 1574 D 1574
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 516 bits (1329), Expect = e-145
Identities = 453/1565 (28%), Positives = 650/1565 (41%), Gaps = 270/1565 (17%)
Query: 1174 LIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQ 1233
L+ + C P + L C D E + G C T+ G+ C C GF
Sbjct: 12 LLALWLCCAAPAH-----ALQCRDGYEPCVNEGMCVTY---HNGTGYCKCPEGFL----G 59
Query: 1234 RSCTDIDECEDNPNICDGGQCTN--IPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNIC 1291
C D CE N +GG C + G+ C C GF ED + + C ++
Sbjct: 60 EYCQHRDPCEKN-RCQNGGTCVAQAMLGKATCRCASGF-TGEDCQYSTS-HPCFVSRPCL 116
Query: 1292 LSGTCEN-TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSC 1350
GTC ++ ++ C C +G++GK+ C + C +H C + CT A F C C
Sbjct: 117 NGGTCHMLSRDTYECTCQVGFTGKE----CQWTDACL--SHPCANGSTCTTVANQFSCKC 170
Query: 1351 SPGWIGDGIKC-TDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLD-EC 1408
G+ G KC TD++EC H C C N GSY+C C +G+TG C L C
Sbjct: 171 LTGFTGQ--KCETDVNECDIPGH-CQHGGTCLNLPGSYQCQCPQGFTGQ--YCDSLYVPC 225
Query: 1409 SENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE-DIDECSLPNICVFGTCHNLPGL 1467
+ + C NG G + EC+ +P +G CE +ID+C G C +
Sbjct: 226 APSP--CVNGGTCRQTGDFTFECNC--LPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNT 281
Query: 1468 FRCECEIGYELDRSGGNCT-DVNECL-DPTTCISGN-CVNTPGSYICDCPPDFELNPTRV 1524
+ C C + +G CT DV+ECL P C +G C N G Y C C + +
Sbjct: 282 YNCRCPPQW----TGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSE 337
Query: 1525 GCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAW-GTPCEMCPAVNTS 1583
D +C P D S KA C L A PC +T+
Sbjct: 338 NIDDCAFASC----TPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTN 393
Query: 1584 ----EYKILCPGGEGFRPNPITVILEDIDECQEL-PGLCQ-GGKCINTFGSFQCRCPTGY 1637
+Y CP +G++ T ED+DEC C+ GKC+NT G+F C C GY
Sbjct: 394 PLNGQYICTCP--QGYKGADCT---EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY 448
Query: 1638 YLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYR 1697
R D+NEC + TC + +G +TC+C P + V+
Sbjct: 449 ---AGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVH--------------- 490
Query: 1698 NYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCE---QCPIPSTDEFATLCGSQRPG 1754
C I + PC QC + + F LC PG
Sbjct: 491 -----------------------CELEINECQSNPCVNNGQC-VDKVNRFQCLCP---PG 523
Query: 1755 FVIDIYTGLPVDIDECREIPGVCENGV-CINMVGSFRCECPVGFFYNDKLLVCEDIDECQ 1813
F + +DID+C P C NG CI+ + C+C GF +L E+ID C
Sbjct: 524 FTGPV---CQIDIDDCSSTP--CLNGAKCIDHPNGYECQCATGF---TGVLCEENIDNCD 575
Query: 1814 NGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDR-NECQEIPNICSHGQCIDTVGSF 1872
P + +C + SY C C PGY C+D+ +EC P + + G+CID V +
Sbjct: 576 PDPC--HHGQCQDGIDSYTCICNPGYMGAI---CSDQIDECYSSPCL-NDGRCIDLVNGY 629
Query: 1873 YCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVD 1932
C C G + + ++ ++C + C +G C + I ++C C+ GF N ID+D
Sbjct: 630 QCNCQPGTSGVNCE---INFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCN--IDID 684
Query: 1933 ECASGNGNLCRNGQ-CINTVGSFQCQCNEGYEVAPDGRTCVD-INECLLEPRKCAPGTCQ 1990
ECAS N CR G CIN V F+C C EG P +C +NECL P C G C
Sbjct: 685 ECAS---NPCRKGATCINGVNGFRCICPEG----PHHPSCYSQVNECLSNP--CIHGNCT 735
Query: 1991 NLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSS 2048
Y+C+C G+ N CE D +EC+ P C G TC N ++C C +GF
Sbjct: 736 GGLSGYKCLCDAGWVGIN--CEVDKNECLSNP--CQNGGTCDNLVNGYRCTCKKGFK--- 788
Query: 2049 SGRRCQDLRMSYCYAK--FEGGKCSSPKSRNHSKQECCCALKGEGWG----------DPC 2096
G CQ + + C + G C + S C C L G +PC
Sbjct: 789 -GYNCQ-VNIDECASNPCLNQGTCFD----DISGYTCHCVLPYTGKNCQTVLAPCSPNPC 842
Query: 2097 E---LCPTEPD-EAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCE 2152
E +C P+ E++ +C G +D+DEC HG C NT GSY CE
Sbjct: 843 ENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECISKPCMNHGLCHNTQGSYMCE 898
Query: 2153 CPFGYILAGNEC-VDTDECSVGNPCGN-GTCKNVIGGFECTCEEGFEPGPMMTCEDINEC 2210
CP G+ +G +C D D+C + NPC N G+C + + F C C GF T D+NEC
Sbjct: 899 CPPGF--SGMDCEEDIDDC-LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT--DMNEC 953
Query: 2211 AQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQM----ECK 2266
P C + SY CKC G+ D CE ++CTE C
Sbjct: 954 LSEPCKNGGTCSDYVNSYTCKCQAGF----------DGVHCENNINECTESSCFNGGTCV 1003
Query: 2267 NLIGTYMCICGPGYQRRPDGEGCVDE-NECQTKPGICENGRCLNTRGSYTCECNDGFTAS 2325
+ I ++ C+C G+ G C+ E NEC + P + E G C++ G+Y C C G+T
Sbjct: 1004 DGINSFSCLCPVGF----TGSFCLHEINECSSHPCLNE-GTCVDGLGTYRCSCPLGYTGK 1058
Query: 2326 PNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT------KSECCCDGGRGW-GPHCEIC 2378
C + L N+C S +N T +S+C C GW G +C++
Sbjct: 1059 ----NC----------QTLVNLCS-RSPCKNKGTCVQKKAESQCLCPS--GWAGAYCDVP 1101
Query: 2379 PFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDIT 2438
+A + RG + V H +G C+N +++C C GY T
Sbjct: 1102 NVSCDIAASR-----RGVL----------VEHLCQHSGVCINAGNTHYCQCPLGY----T 1142
Query: 2439 GTSCVD-LNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCK-DLDECATKQHNC 2496
G+ C + L+EC P C + G Y+C C GY G +C+ ++DEC +
Sbjct: 1143 GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY----QGVNCEYEVDECQNQPCQN 1198
Query: 2497 QFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGF 2556
C++ + F C CPPG C +N + + C + G C + G ++C C GF
Sbjct: 1199 GGTCIDLVNHFKCSCPPG--TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGF 1256
Query: 2557 SLDQTGSSCE-DVDECEGNHRCQHG---CQNIIGGYRCSCPQGYLQHY--QWNQCVDENE 2610
+ G CE D++EC N G C + Y C C + + + +
Sbjct: 1257 A----GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMP 1312
Query: 2611 CLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGY 2670
CL+ C AS N + C CP GF G + + CG + C +T G
Sbjct: 1313 CLNGGTCAVAS--NMPDGFICRCPPGF------SGARCQSSCGQVKCRKGEQCVHTASGP 1364
Query: 2671 LCGCP 2675
C CP
Sbjct: 1365 RCFCP 1369
Score = 481 bits (1239), Expect = e-135
Identities = 479/1768 (27%), Positives = 692/1768 (39%), Gaps = 342/1768 (19%)
Query: 510 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINT-DGSFHCVCNAGFHVTRDGK 568
++ QCR GY+ + N G C+ +G+ +C C GF G+
Sbjct: 23 AHALQCRDGYEPCV------------------NEGMCVTYHNGTGYCKCPEGFL----GE 60
Query: 569 NCEDMDECSIRNMCLN-GMCINED--GSFKCICKPGFQLASDGRYCKDINECETPGICMN 625
C+ D C +N C N G C+ + G C C GF D +Y + C C+N
Sbjct: 61 YCQHRDPCE-KNRCQNGGTCVAQAMLGKATCRCASGF-TGEDCQYSTS-HPCFVSRPCLN 117
Query: 626 GRCVN--TDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSEC 683
G + + +Y C C VG G+ C T
Sbjct: 118 GGTCHMLSRDTYECTC----QVGFTGKECQWTD--------------------------- 146
Query: 684 CCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLR 743
C S A G C Q S + C +G +D+NEC + G C NL
Sbjct: 147 ACLSHPCANGSTCTTVANQFSCK----CLTGFTGQKCETDVNECDIPGHCQHGGTCLNLP 202
Query: 744 GTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPG-SFVCTCPKGFIYKPDL 802
G+Y+C C G+ TG+ C + S + G CR T +F C C GF +
Sbjct: 203 GSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF----EG 254
Query: 803 KTCE-DIDECESSPCIN-GVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDG 860
TCE +ID+C + C N GVC + ++ C C + T C E + Q
Sbjct: 255 STCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQW----TGQFCTEDVDECLLQ---PN 307
Query: 861 RCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQC-EDIDECEVFPG 919
C+ NG T C++ +G +C G+S G C E+ID+C F
Sbjct: 308 ACQ---NGGT-----CANRNGGYGC---------VCVNGWS---GDDCSENIDDC-AFAS 346
Query: 920 VCKNGLCVNTRGSFKCQCPSGMTLDATGRIC-LDIRLETCFLR--YEDEEC-TLPIAGRH 975
C++ SF C CP G G +C LD + C ++ C T P+ G++
Sbjct: 347 CTPGSTCIDRVASFSCMCPEG----KAGLLCHLD---DACISNPCHKGALCDTNPLNGQY 399
Query: 976 RMDACCCSVG--AAWGTEECEECPMRNTP--EYEELCPRGPGFATKEITNGKPFFK---D 1028
C C G A TE+ +EC M N+ E+ C G E G + D
Sbjct: 400 ---ICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMD 456
Query: 1029 INECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNC-TDIDECRISPDLCGRGQCV 1087
INEC P C + IG F C C GF + +C +I+EC+ +P GQCV
Sbjct: 457 INECHSDPCQ-NDATCLDKIGGFTCLCMPGF----KGVHCELEINECQSNP-CVNNGQCV 510
Query: 1088 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1147
+ F+C C G+ +DID+C P L G C + Y C+C G
Sbjct: 511 DKVNRFQCLCPPGFTGPVCQ----IDIDDCSSTPCL-NGAKCIDHPNGYECQCATGF--- 562
Query: 1148 PNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVD-IDECSIMNG 1206
+ +I+ C+ C +G+C + I Y C CNPGY C D IDEC
Sbjct: 563 TGVLCEENIDNCDPDP--CHHGQCQDGIDSYTCICNPGYMGA----ICSDQIDECYSSPC 616
Query: 1207 GCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCY 1266
+ C + Y+C+CQPG + + + + D+C NP C G C + Y C+C
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCE---INFDDCASNP--CIHGICMDGINRYSCVCS 671
Query: 1267 DGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFICHCDMGYSGKKGKTGCTDINE 1325
GF + +D++EC NP C G TC N F C C G + + +NE
Sbjct: 672 PGFTG---QRCNIDIDECASNP--CRKGATCINGVNGFRCICP---EGPHHPSCYSQVNE 723
Query: 1326 CEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKC-TDLDECSNGTHMCSQHADCKNTM 1384
C N H CT +KC C GW+ GI C D +EC ++ C C N +
Sbjct: 724 C---LSNPCIHGNCTGGLSGYKCLCDAGWV--GINCEVDKNECL--SNPCQNGGTCDNLV 776
Query: 1385 GSYRCLCKEGYTGDGFTC-TDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKA 1443
YRC CK+G+ G+ C ++DEC+ N L G C + GY C C + + GK
Sbjct: 777 NGYRCTCKKGF--KGYNCQVNIDECASNPCL-NQGTCFDDISGYTCHCVLPYT----GKN 829
Query: 1444 CEDIDECSLPNICV-FGTCHNLPGL--FRCECEIGYELDRSGGNCT-DVNECLDPTTCIS 1499
C+ + PN C C P + C C G++ G CT D++EC+
Sbjct: 830 CQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDIDECISKPCMNH 885
Query: 1500 GNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSK 1559
G C NT GSY+C+CPP F D + C NG + GV+
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPC--------QNGGSCMD-----GVNT 932
Query: 1560 ASCCC-----------SLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDID 1608
SC C + + PC+ + C GF +I+
Sbjct: 933 FSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDG---VHCENNIN 989
Query: 1609 ECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVG 1668
EC E GG C++ SF C CP G+ + ++NEC + GTC + +G
Sbjct: 990 ECTE-SSCFNGGTCVDGINSFSCLCPVGF---TGSFCLHEINECSSHPCLNEGTCVDGLG 1045
Query: 1669 NYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRA 1728
Y C CP Y G NC + +LC R+ + TC + + C C A
Sbjct: 1046 TYRCSCPLGYT----GKNCQTL-VNLCSRSPCKNKGTC----VQKKAESQCLCPSGWAGA 1096
Query: 1729 WNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCE-NGVCINMVG 1787
+ C +P+ + S+R G +++ +C+ +GVCIN
Sbjct: 1097 Y------CDVPNVS--CDIAASRR-GVLVE----------------HLCQHSGVCINAGN 1131
Query: 1788 SFRCECPVGFFYNDKLLVCED-IDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ 1846
+ C+CP+G+ + CE+ +DEC + P CQ A C + G YRC+C PGY+ +
Sbjct: 1132 THYCQCPLGYTGS----YCEEQLDECASNP-CQHGATCSDFIGGYRCECVPGYQGVNCEY 1186
Query: 1847 CNDRNECQEIPNICSH-GQCIDTVGSFYCLCHTGFKTNDDQTMCLD-INECER--DACGN 1902
+ +ECQ P C + G CID V F C C G + +C + I++C R
Sbjct: 1187 --EVDECQNQP--CQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDCARGPHCLNG 1238
Query: 1903 GTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGY 1962
G C + IG ++CRC GF D++EC S + + CI + C C +
Sbjct: 1239 GQCMDRIGGYSCRCLPGFAGERCEG--DINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296
Query: 1963 EVAPDGRTCVDINECLLEPRKCAPGTC---QNLDGSYRCICPPGYSLQNEKCEDIDECVE 2019
GR C + + GTC N+ + C CPPG+S +C+ V+
Sbjct: 1297 ----TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFS--GARCQSSCGQVK 1350
Query: 2020 EPEICALG-TCSNTEGSFKCLCPEGFSLSSSGRRCQD-LRMSYCYAKFEGGKCSSPKSRN 2077
C G C +T +C CP S R C+ S C GG C +
Sbjct: 1351 ----CRKGEQCVHTASGPRCFCP-------SPRDCESGCASSPCQ---HGGSCHPQRQPP 1396
Query: 2078 HSKQECCCALKGEGWGDPCELC----PTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKE 2133
+ +C G CEL T P Q C
Sbjct: 1397 YYSCQCAPPFS----GSRCELYTAPPSTPPATCLSQYC---------------------- 1430
Query: 2134 PDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDE-----CSVGNPCG---NGTCKNVI 2185
D + G C S+ C+ G +C T E CS PC N C +
Sbjct: 1431 ADKARDGVCDEACNSHACQWD------GGDCSLTMENPWANCSSPLPCWDYINNQCDELC 1484
Query: 2186 GGFECTCEEGFEPGPMMTCEDINECAQN 2213
EC + G TC+ CA +
Sbjct: 1485 NTVECLFDNFECQGNSKTCKYDKYCADH 1512
Score = 478 bits (1230), Expect = e-134
Identities = 438/1544 (28%), Positives = 627/1544 (40%), Gaps = 377/1544 (24%)
Query: 1278 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHA 1337
C D E +N +C+ T N G+ C C G+ G+ C + CE G
Sbjct: 28 CRDGYEPCVNEGMCV--TYHN--GTGYCKCPEGFLGEY----CQHRDPCEKNRCQNGGTC 79
Query: 1338 VCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGT-HMCSQHADCKN-------TMGSYRC 1389
V G C C+ G+ G+ +C T H C C N + +Y C
Sbjct: 80 VAQAMLGKATCRCASGFTGE--------DCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
Query: 1390 LCKEGYTGDGFTCTDLDECSENLNLCGNGQ-CLNAPGGYRCECDMGFVPSADGKACE-DI 1447
C+ G+TG C D C + C NG C + C+C GF G+ CE D+
Sbjct: 132 TCQVGFTGK--ECQWTDACLSHP--CANGSTCTTVANQFSCKCLTGFT----GQKCETDV 183
Query: 1448 DECSLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTP 1506
+EC +P C G TC NLPG ++C+C G+ +G C + P+ C++G
Sbjct: 184 NECDIPGHCQHGGTCLNLPGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQT 239
Query: 1507 GSYI--CDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCC 1564
G + C+C P FE + D + C NG GV+ +C
Sbjct: 240 GDFTFECNCLPGFEGSTCERNIDDCPNHRC--------QNGGVCVD-----GVNTYNC-- 284
Query: 1565 SLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ-GGKCI 1623
CP T ++ ED+DEC P CQ GG C
Sbjct: 285 -----------RCPPQWTGQF-----------------CTEDVDECLLQPNACQNGGTCA 316
Query: 1624 NTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPG-TCYNTVGNYTCICPPDYMQVN 1682
N G + C C G+ ++ + +++++C C PG TC + V +++C+CP +
Sbjct: 317 NRNGGYGCVCVNGWSGDDCS---ENIDDCAFAS-CTPGSTCIDRVASFSCMCPEGKAGL- 371
Query: 1683 GGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTD 1742
LC+ D + N K C N P
Sbjct: 372 -----------LCH---------LDDACISNPCHKGALCDTN--------------PLNG 397
Query: 1743 EFATLCGSQRPGFVIDIYTGLPVDIDECREI-PGVCEN-GVCINMVGSFRCECPVGFFYN 1800
++ C G D+DEC CE+ G C+N G+F CEC G+
Sbjct: 398 QYICTCPQGYKG------ADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP 451
Query: 1801 DKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCN-DRNECQEIPN 1858
CE DI+EC + P CQ +A C++ G + C C PG++ C + NECQ P
Sbjct: 452 R----CEMDINECHSDP-CQNDATCLDKIGGFTCLCMPGFKGV---HCELEINECQSNPC 503
Query: 1859 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT-CRNTIGSFNCRCN 1917
+ ++GQC+D V F CLC GF Q +DI++C C NG C + + C+C
Sbjct: 504 V-NNGQCVDKVNRFQCLCPPGFTGPVCQ---IDIDDCSSTPCLNGAKCIDHPNGYECQCA 559
Query: 1918 HGF--ILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVD-I 1974
GF +L N +D C + + C +GQC + + S+ C CN GY G C D I
Sbjct: 560 TGFTGVLCEEN----IDNC---DPDPCHHGQCQDGIDSYTCICNPGYM----GAICSDQI 608
Query: 1975 NECLLEPRKCA-PGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICALGTCSNT 2032
+EC P C G C +L Y+C C PG S N CE + D+C P C G C +
Sbjct: 609 DECYSSP--CLNDGRCIDLVNGYQCNCQPGTSGVN--CEINFDDCASNP--CIHGICMDG 662
Query: 2033 EGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGW 2092
+ C+C GF+ G+RC + +C+S R + C + G
Sbjct: 663 INRYSCVCSPGFT----GQRCN----------IDIDECASNPCRKGAT--CINGVNG--- 703
Query: 2093 GDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCE 2152
FR ICP G ++EC + C HG C Y+C
Sbjct: 704 --------------FRCICPEGPH----HPSCYSQVNECLS-NPCIHGNCTGGLSGYKCL 744
Query: 2153 CPFGYILAGNEC-VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCE-DINE 2209
C G++ G C VD +EC + NPC NG TC N++ G+ CTC++GF+ C+ +I+E
Sbjct: 745 CDAGWV--GINCEVDKNEC-LSNPCQNGGTCDNLVNGYRCTCKKGFKG---YNCQVNIDE 798
Query: 2210 CAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRM--------CKDEDECEEGKHDCTEK 2261
CA NP L C + Y C C + Y + + + C++ C+E +
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN----- 853
Query: 2262 QMECKNLIGTYMCICGPGYQRRPDGEGC-VDENECQTKPGICEN-GRCLNTRGSYTCECN 2319
+Y C+C PG+Q G+ C +D +EC +KP C N G C NT+GSY CEC
Sbjct: 854 -------FESYTCLCAPGWQ----GQRCTIDIDECISKP--CMNHGLCHNTQGSYMCECP 900
Query: 2320 DGFTASPNQ---DECLDN---REGYCF-----------------------TEVLQNMCQI 2350
GF+ + D+CL N G C E L C+
Sbjct: 901 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN 960
Query: 2351 GSSNRNPVTKSECCCDGGRGWGPHCE---------ICPFQGTV-----AFKKLCPHGRGF 2396
G + + V C C G G HCE C GT +F LCP G
Sbjct: 961 GGTCSDYVNSYTCKCQAGFD-GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTG 1019
Query: 2397 MTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDL-NECNQAPKPC 2455
+I+EC H G CV+ G+Y C C GYT G +C L N C+++P
Sbjct: 1020 SFCLHEINECSS-HPCLNEGTCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSPCKN 1074
Query: 2456 NFICKNTEGSYQCSCPKGYILQEDGRSCK----DLDECATK-----QHNCQF--LCVNTI 2504
C + QC CP G+ G C D A++ +H CQ +C+N
Sbjct: 1075 KGTCVQKKAESQCLCPSGWA----GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAG 1130
Query: 2505 GGFTCKCPPGFTQHHTSCIDN-NECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGS 2563
C+CP G+T + C + +EC S N C C + G + CEC G+ G
Sbjct: 1131 NTHYCQCPLGYTGSY--CEEQLDECAS--NPCQHGATCSDFIGGYRCECVPGYQ----GV 1182
Query: 2564 SCE-DVDECEGNHRCQHG--CQNIIGGYRCSCP---QGYLQHYQWNQCVDENECLSAHIC 2617
+CE +VDEC+ N CQ+G C +++ ++CSCP +G L + C CL+
Sbjct: 1183 NCEYEVDECQ-NQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLN---- 1237
Query: 2618 GGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGS----------------------- 2654
G C + +G Y C C GF E+ G DINEC S
Sbjct: 1238 -GGQCMDRIGGYSCRCLPGFAGERCEG---DINECLSNPCSSEGSLDCIQLTNDYLCVCR 1293
Query: 2655 ---------------AQAPCSYG-----CSNTEGGYLCGCPPGY 2678
Q PC G SN G++C CPPG+
Sbjct: 1294 SAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF 1337
Score = 477 bits (1227), Expect = e-134
Identities = 471/1655 (28%), Positives = 668/1655 (40%), Gaps = 379/1655 (22%)
Query: 460 CQN-GRCIPTP-GSCRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQ--GSYTCQ 514
C N G C+ G+ C+C +GF L C D CEKN C GG C+ G TC+
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGF---LGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCR 91
Query: 515 CRAGYQSTLTRTECR--DIDECLQNGRICNNGRC-INTDGSFHCVCNAGFHVTRDGKNCE 571
C +G+ T +C+ C + N G C + + ++ C C GF GK C+
Sbjct: 92 CASGF----TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF----TGKECQ 143
Query: 572 DMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMN-GRC 628
D C + + C NG C F C C GF G+ C+ D+NEC+ PG C + G C
Sbjct: 144 WTDAC-LSHPCANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQHGGTC 198
Query: 629 VNTDGSYRCECFPGLAVGLDGRVCVDTHM---RSTCYGGYKRGQCIKPLFGAVTKSECCC 685
+N GSY+C+C G G+ C ++ S C G G C + G T C
Sbjct: 199 LNLPGSYQCQC----PQGFTGQYCDSLYVPCAPSPCVNG---GTCRQT--GDFTFECNCL 249
Query: 686 ASTEYAFGEPCQ----PCP---AQNSA-------EYQALCSSGPGMTSAGSDINECALDP 731
E G C+ CP QN Y C D++EC L P
Sbjct: 250 PGFE---GSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP 306
Query: 732 DICPN-GICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ-CRNTPGSFV 789
+ C N G C N G Y C+C +G+ D +N I++C S C G C + SF
Sbjct: 307 NACQNGGTCANRNGGYGCVCVNGWSGDDCSEN---IDDCAFAS--CTPGSTCIDRVASFS 361
Query: 790 CTCPKGFIYKPDLKTCEDIDECESSPCING-VCKNSP--GSFICEC-SSESTLDPTKTI- 844
C CP+G K L C D C S+PC G +C +P G +IC C D T+ +
Sbjct: 362 CMCPEG---KAGL-LCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD 417
Query: 845 -CIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTL----CQVDP----- 894
C C G+C +N +GA C L G C + C DP
Sbjct: 418 ECAMANSNPCEHA---GKC-VNTDGAF----HCECLKGYAGPRCEMDINECHSDPCQNDA 469
Query: 895 -----------ICGKGYSRIKGTQCE-DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMT 942
+C G+ KG CE +I+EC+ P V NG CV+ F+C CP G
Sbjct: 470 TCLDKIGGFTCLCMPGF---KGVHCELEINECQSNPCV-NNGQCVDKVNRFQCLCPPGF- 524
Query: 943 LDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTP 1002
TG +C ++D CS +C + P
Sbjct: 525 ---TGPVC-------------------------QIDIDDCSSTPCLNGAKCIDHP----N 552
Query: 1003 EYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGF--A 1060
YE C G G ++I+ C P C HG+C++ I S+ C C+ G+ A
Sbjct: 553 GYECQCATG--------FTGVLCEENIDNCD--PDPCHHGQCQDGIDSYTCICNPGYMGA 602
Query: 1061 LDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC-MDIDECQR 1119
+ S++ IDEC SP L G+C++ ++C C G SG NC ++ D+C
Sbjct: 603 ICSDQ-----IDECYSSPCL-NDGRCIDLVNGYQCNCQPG-TSGV----NCEINFDDCAS 651
Query: 1120 DPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNG-RCVNLIGKY 1178
+P C G+C + Y C C PG IDI+EC +++ C G C+N + +
Sbjct: 652 NP--CIHGICMDGINRYSCVCSPGF---TGQRCNIDIDEC--ASNPCRKGATCINGVNGF 704
Query: 1179 QCACNPGYHSTPDRLFCV-DIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCT 1237
+C C G H C ++EC + N CT Y+C C G+ + +
Sbjct: 705 RCICPEGPHHPS----CYSQVNEC-LSNPCIHGNCTGGLSGYKCLCDAGWVGINCE---V 756
Query: 1238 DIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLS-GTC 1296
D +EC NP +GG C N+ YRC C GF + V+++EC NP CL+ GTC
Sbjct: 757 DKNECLSNP-CQNGGTCDNLVNGYRCTCKKGF---KGYNCQVNIDECASNP--CLNQGTC 810
Query: 1297 ENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAG--SFKCSCSPGW 1354
+ + CHC + Y+GK +T + + C AVC + S+ C C+PGW
Sbjct: 811 FDDISGYTCHCVLPYTGKNCQTVLAPCS-----PNPCENAAVCKESPNFESYTCLCAPGW 865
Query: 1355 IGDGIKCT-DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTC-TDLDECSENL 1412
G +CT D+DEC + C H C NT GSY C C G++ G C D+D+C
Sbjct: 866 --QGQRCTIDIDECI--SKPCMNHGLCHNTQGSYMCECPPGFS--GMDCEEDIDDCL--A 917
Query: 1413 NLCGN-GQCLNAPGGYRCECDMGFVPSADGKACE-DIDECSLPNICVFGTCHNLPGLFRC 1470
N C N G C++ + C C GF G C+ D++EC GTC + + C
Sbjct: 918 NPCQNGGSCMDGVNTFSCLCLPGFT----GDKCQTDMNECLSEPCKNGGTCSDYVNSYTC 973
Query: 1471 ECEIGYELDRSGGNC-TDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDT 1529
+C+ G++ G +C ++NEC + + G CV+ S+ C CP F
Sbjct: 974 KCQAGFD----GVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF------------ 1017
Query: 1530 RSGNCYLDIRPRGDNGDTACSNE----IGVGVSKASCCCS-LGKAWGTPCEMC---PAVN 1581
C +I + C NE G+G + SC GK T +C P N
Sbjct: 1018 TGSFCLHEI---NECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKN 1074
Query: 1582 -------TSEYKILCPGGEGFRPNPITVILEDIDECQE---LPGLCQ-GGKCINTFGSFQ 1630
+E + LCP G + + DI + + LCQ G CIN +
Sbjct: 1075 KGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY 1134
Query: 1631 CRCPTGYYLNEDTRVCDD-VNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMD 1689
C+CP GY C++ ++EC + TC + +G Y C C P Y VN
Sbjct: 1135 CQCPLGY----TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVN------- 1183
Query: 1690 MRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCG 1749
C Y + N+PC+
Sbjct: 1184 -------------------------------CEYEVDECQNQPCQ--------------- 1197
Query: 1750 SQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDI 1809
G CI++V F+C CP G LL E+I
Sbjct: 1198 ----------------------------NGGTCIDLVNHFKCSCPPG---TRGLLCEENI 1226
Query: 1810 DECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQC-NDRNECQEIPNICSHG---QC 1865
D+C GP C +C++ G Y C C PG+ + +C D NEC + N CS C
Sbjct: 1227 DDCARGPHCLNGGQCMDRIGGYSCRCLPGF---AGERCEGDINEC--LSNPCSSEGSLDC 1281
Query: 1866 IDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGN-GTC---RNTIGSFNCRCNHGFI 1921
I + C+C + F +T ++ C + C N GTC N F CRC GF
Sbjct: 1282 IQLTNDYLCVCRSAFTGRHCETF---VDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF- 1337
Query: 1922 LSHNNDCIDVDECASGNGNL-CRNG-QCINTVGSFQCQCNEGYEVAPDGRTCVDINECLL 1979
C S G + CR G QC++T +C C P R C + C
Sbjct: 1338 --------SGARCQSSCGQVKCRKGEQCVHTASGPRCFC-------PSPRDCE--SGCAS 1380
Query: 1980 EPRKCAPGTC--QNLDGSYRCICPPGYSLQNEKCE 2012
P + G+C Q Y C C P +S +CE
Sbjct: 1381 SPCQHG-GSCHPQRQPPYYSCQCAPPFS--GSRCE 1412
Score = 416 bits (1068), Expect = e-115
Identities = 412/1481 (27%), Positives = 582/1481 (39%), Gaps = 355/1481 (23%)
Query: 1039 CTHGKCRN--------TIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP 1090
C +C+N +G CRC SGF E+ + C +S G C
Sbjct: 68 CEKNRCQNGGTCVAQAMLGKATCRCASGFT--GEDCQYSTSHPCFVSRPCLNGGTCHMLS 125
Query: 1091 GD-FECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPN 1149
D +EC C G+ K C D C P G C + C+C G
Sbjct: 126 RDTYECTCQVGFTG-----KECQWTDACLSHPC-ANGSTCTTVANQFSCKCLTGFT---G 176
Query: 1150 ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCE 1209
D+NEC++ H G C+NL G YQC C G+ V +NGG
Sbjct: 177 QKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGG-- 234
Query: 1210 TFCTNSEGSYECSCQPGFALMPDQRS---------------------------------- 1235
T + ++EC+C PGF +R+
Sbjct: 235 TCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQF 294
Query: 1236 CT-DIDECEDNPNIC-DGGQCTNIPGEYRCLCYDG--------------FMASEDMKTCV 1279
CT D+DEC PN C +GG C N G Y C+C +G F + TC+
Sbjct: 295 CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCI 354
Query: 1280 DVNE--------------CDLNPNICLSGTCEN--------TKGSFICHCDMGYSGKKGK 1317
D C L+ + C+S C G +IC C GY G
Sbjct: 355 DRVASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKG---- 409
Query: 1318 TGCT-DINECEIGAHNCGKHA-VCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCS 1375
CT D++EC + N +HA C NT G+F C C G+ G + D++EC + C
Sbjct: 410 ADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE-MDINECHSDP--CQ 466
Query: 1376 QHADCKNTMGSYRCLCKEGYTG---------------------------------DGFT- 1401
A C + +G + CLC G+ G GFT
Sbjct: 467 NDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG 526
Query: 1402 --C-TDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACED-IDECSLPNICV 1457
C D+D+CS L G +C++ P GY C+C GF G CE+ ID C P+ C
Sbjct: 527 PVCQIDIDDCSSTPCLNG-AKCIDHPNGYECQCATGFT----GVLCEENIDNCD-PDPCH 580
Query: 1458 FGTCHNLPGLFRCECEIGYELDRSGGNCTD-VNECLDPTTCISGNCVNTPGSYICDCPPD 1516
G C + + C C GY G C+D ++EC G C++ Y C+C P
Sbjct: 581 HGQCQDGIDSYTCICNPGY----MGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQP- 635
Query: 1517 FELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGV-GVSKASCCCSLG-------- 1567
T NC ++ D C + I + G+++ SC CS G
Sbjct: 636 -----------GTSGVNCEINF---DDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNI 681
Query: 1568 ---KAWGTPCEM-CPAVN-TSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKC 1622
+ PC +N + ++ +CP G P+ ++EC P C G C
Sbjct: 682 DIDECASNPCRKGATCINGVNGFRCICPEGP-HHPS----CYSQVNECLSNP--CIHGNC 734
Query: 1623 INTFGSFQCRCPTGYY-LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDY--- 1678
++C C G+ +N + D NEC + GTC N V Y C C +
Sbjct: 735 TGGLSGYKCLCDAGWVGINCEV----DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGY 790
Query: 1679 -MQVN----GGNNCMDMRRSLCYRNYYADNQTCDGELLF---NMTKKMCCCSYNIGRAWN 1730
QVN N C++ + C+ + TC L + N + CS N
Sbjct: 791 NCQVNIDECASNPCLN--QGTCFDD--ISGYTCHCVLPYTGKNCQTVLAPCSPN------ 840
Query: 1731 KPCEQCPI----PSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINM 1785
PCE + P+ + + LC PG+ T +DIDEC P C N G+C N
Sbjct: 841 -PCENAAVCKESPNFESYTCLCA---PGWQGQRCT---IDIDECISKP--CMNHGLCHNT 891
Query: 1786 VGSFRCECPVGFFYNDKLLVC-EDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTST 1844
GS+ CECP GF D C EDID+C P CQ C++ ++ C C PG FT
Sbjct: 892 QGSYMCECPPGFSGMD----CEEDIDDCLANP-CQNGGSCMDGVNTFSCLCLPG--FTGD 944
Query: 1845 GQCNDRNECQEIPNICSH-GQCIDTVGSFYCLCHTGFKTNDDQTMC-LDINECERDACGN 1902
D NEC P C + G C D V S+ C C GF D C +INEC +C N
Sbjct: 945 KCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGF----DGVHCENNINECTESSCFN 998
Query: 1903 -GTCRNTIGSFNCRCNHGFILSHNNDCI-DVDECASGNGNLCRN-GQCINTVGSFQCQCN 1959
GTC + I SF+C C GF S C+ +++EC+S + C N G C++ +G+++C C
Sbjct: 999 GGTCVDGINSFSCLCPVGFTGSF---CLHEINECSS---HPCLNEGTCVDGLGTYRCSCP 1052
Query: 1960 EGYEVAPDGRTCVD-INECLLEPRKCAPGTCQNLDGSYRCICPPGYS-----LQNEKCE- 2012
GY G+ C +N C P K GTC +C+CP G++ + N C+
Sbjct: 1053 LGY----TGKNCQTLVNLCSRSPCK-NKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
Query: 2013 -DIDECVEEPEICA-LGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC 2070
V +C G C N + C CP G++ SYC + + +C
Sbjct: 1108 AASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT------------GSYCEEQLD--EC 1153
Query: 2071 SSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQI-CPYGSGIIVGPDDSAVDMD 2129
+S ++ + C G G CE P ++ + C Y ++D
Sbjct: 1154 ASNPCQHGA---TCSDFIG---GYRCECVP-----GYQGVNCEY-------------EVD 1189
Query: 2130 ECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDT-DECSVGNPCGN-GTCKNVIGG 2187
EC+ G CI+ ++C CP G G C + D+C+ G C N G C + IGG
Sbjct: 1190 ECQNQPCQNGGTCIDLVNHFKCSCPPG--TRGLLCEENIDDCARGPHCLNGGQCMDRIGG 1247
Query: 2188 FECTCEEGFEPGPMMTCE-DINECAQNPLLC--AFRCVNTYGSYECKCPVGYVLREDRRM 2244
+ C C GF CE DINEC NP + C+ Y C C + R
Sbjct: 1248 YSCRCLPGFAG---ERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGR----- 1299
Query: 2245 CKDEDECEEGKHDCTEKQMEC---------KNLIGTYMCICGPGYQRRPDGEGCVDENEC 2295
CE C QM C N+ ++C C PG+ G C ++ C
Sbjct: 1300 -----HCETFVDVC--PQMPCLNGGTCAVASNMPDGFICRCPPGF----SGARC--QSSC 1346
Query: 2296 -QTKPGICENG-RCLNTRGSYTC------ECNDGFTASPNQ 2328
Q K C G +C++T C +C G +SP Q
Sbjct: 1347 GQVK---CRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQ 1384
Score = 395 bits (1014), Expect = e-109
Identities = 421/1475 (28%), Positives = 590/1475 (40%), Gaps = 333/1475 (22%)
Query: 221 CEMCPAQPHPCRRGFIPNIRTGA---------------------CQDVDECQAIPGLCQ- 258
C PA CR G+ P + G CQ D C+ CQ
Sbjct: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCE--KNRCQN 75
Query: 259 GGNCI--NTVGSFECKCPAG--------------------------HKLNE--------- 281
GG C+ +G C+C +G H L+
Sbjct: 76 GGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQV 135
Query: 282 --VSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC-IDVR----PG 334
++C+ D C + P G CT + + CKC GF G +C DV PG
Sbjct: 136 GFTGKECQWTDACLSHP-CANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPG 190
Query: 335 YCYTALTNGRCSNQLPQSITKMQCCCDAG----RCWSPGVTVAPEMC----PIRATEDFN 386
+C G C N LP S QC C G C S V AP C R T DF
Sbjct: 191 HCQ---HGGTCLN-LPGS---YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFT 243
Query: 387 KLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLP 446
C+ +PG P G + Y R PP+
Sbjct: 244 FECN---CLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNT--------YNCRCPPQWTG 292
Query: 447 VNVT---DYCQLVRYLCQN-GRCIPTPGSCRCECNKGFQLDLRGE--------------- 487
T D C L CQN G C G C C G+ D E
Sbjct: 293 QFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGST 352
Query: 488 CID--------------------VDECEKNPC-AGGECINN--QGSYTCQCRAGYQSTLT 524
CID D C NPC G C N G Y C C GY+
Sbjct: 353 CIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKG--- 409
Query: 525 RTEC-RDIDEC-LQNGRICNN-GRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRN 580
+C D+DEC + N C + G+C+NTDG+FHC C G+ G CE D++EC
Sbjct: 410 -ADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY----AGPRCEMDINECHSDP 464
Query: 581 MCLNGMCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNGRCVNTDGSYRCEC 639
+ C+++ G F C+C PGF+ G +C+ +INEC++ NG+CV+ ++C C
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCVNNGQCVDKVNRFQCLC 520
Query: 640 FPGLAVGLDGRVC---VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPC 696
PG G VC +D + C G K CI ++ G C
Sbjct: 521 PPGFT----GPVCQIDIDDCSSTPCLNGAK---CI-----------------DHPNGYEC 556
Query: 697 QPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEV 756
Q C++G +I+ C DPD C +G C++ +Y CICN GY
Sbjct: 557 Q-------------CATGFTGVLCEENIDNC--DPDPCHHGQCQDGIDSYTCICNPGY-- 599
Query: 757 DSTGKNCVD-INECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE-DIDECESS 814
G C D I+EC + L D G+C + + C C G CE + D+C S+
Sbjct: 600 --MGAICSDQIDECYSSPCLND-GRCIDLVNGYQCNCQPG----TSGVNCEINFDDCASN 652
Query: 815 PCINGVCKNSPGSFICECSSEST-----LDPTKTICIETIKG-TCWQTVIDGRCEINING 868
PCI+G+C + + C CS T +D + KG TC V RC I G
Sbjct: 653 PCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPEG 711
Query: 869 ATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIK--------GTQCEDIDECEVFPGV 920
S C S + +PC + C G S K G CE +D+ E
Sbjct: 712 PHHPS-CYSQVNECLSNPC----IHGNCTGGLSGYKCLCDAGWVGINCE-VDKNECLSNP 765
Query: 921 CKN-GLCVNTRGSFKCQCPSG-------MTLD-ATGRICLDIRLETCF--LRYEDEECTL 969
C+N G C N ++C C G + +D CL+ TCF + C L
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLN--QGTCFDDISGYTCHCVL 823
Query: 970 PIAGRHRMDACCCSVGAAWGTEECEECPM-RNTPEYEE-LCPRGPGFATKEITNGKPFFK 1027
P G++ C +V A CE + + +P +E C PG+ + T
Sbjct: 824 PYTGKN-----CQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCT------I 872
Query: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFA-LDSEERNCTDIDECRISPDLCGRGQC 1086
DI+EC P + HG C NT GS+ C C GF+ +D EE DID+C +P G G C
Sbjct: 873 DIDECISKPCM-NHGLCHNTQGSYMCECPPGFSGMDCEE----DIDDCLANPCQNG-GSC 926
Query: 1087 VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQ 1145
++ F C C G+ K D++EC +P C+ GG C + SY C+C G
Sbjct: 927 MDGVNTFSCLCLPGFTGD----KCQTDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFD 980
Query: 1146 LSPNISACIDINECELSAHLCPN-GRCVNLIGKYQCACNPGYHSTPDRLFCV-DIDECSI 1203
+ +INEC S+ C N G CV+ I + C C G+ + FC+ +I+ECS
Sbjct: 981 ---GVHCENNINECTESS--CFNGGTCVDGINSFSCLCPVGFTGS----FCLHEINECSS 1031
Query: 1204 MNGGCETFCTNSEGSYECSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQCTNIPGEYR 1262
E C + G+Y CSC G+ ++C T ++ C +P + G C E +
Sbjct: 1032 HPCLNEGTCVDGLGTYRCSCPLGYT----GKNCQTLVNLCSRSP-CKNKGTCVQKKAESQ 1086
Query: 1263 CLCYDGFMASEDMKTCVDVN-ECD--------LNPNICL-SGTCENTKGSFICHCDMGYS 1312
CLC G+ + C N CD L ++C SG C N + C C +GY+
Sbjct: 1087 CLCPSGWAGA----YCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT 1142
Query: 1313 GKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCT-DLDECSNGT 1371
G + ++EC ++ C A C++ G ++C C PG+ G+ C ++DEC N
Sbjct: 1143 GSYCE---EQLDEC--ASNPCQHGATCSDFIGGYRCECVPGY--QGVNCEYEVDECQN-- 1193
Query: 1372 HMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTD-LDECSENLNLCGNGQCLNAPGGYRCE 1430
C C + + ++C C G G C + +D+C+ + GQC++ GGY C
Sbjct: 1194 QPCQNGGTCIDLVNHFKCSCPPGTR--GLLCEENIDDCARGPHCLNGGQCMDRIGGYSCR 1251
Query: 1431 CDMGFVPSADGKACE-DIDECSLPNICVFG---TCHNLPGLFRCECEIGYELDRSGGNC- 1485
C GF G+ CE DI+EC L N C C L + C C + +G +C
Sbjct: 1252 CLPGFA----GERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAF----TGRHCE 1302
Query: 1486 TDVNECLDPTTCISGNCV---NTPGSYICDCPPDF 1517
T V+ C G C N P +IC CPP F
Sbjct: 1303 TFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF 1337
Score = 346 bits (887), Expect = 2e-94
Identities = 389/1510 (25%), Positives = 561/1510 (37%), Gaps = 345/1510 (22%)
Query: 87 HSCGDGFC----SRPNMCTCPSGQIAPSCGSRSIQHCNI--RCMNGGSC----SDDHCLC 136
H C +G + C C +G C + + C+I C +GG+C C C
Sbjct: 151 HPCANGSTCTTVANQFSCKCLTGFTGQKCET-DVNECDIPGHCQHGGTCLNLPGSYQCQC 209
Query: 137 QKGYIGTHCGQ---PVCESGCLNGGRCVAPN----RCACTYGFTGPQCERDYRTGPCFTV 189
+G+ G +C P S C+NGG C C C GF G CER+ P
Sbjct: 210 PQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCP---- 265
Query: 190 ISNQMCQGQLSGIVCT---KTLCCATVGRAWGHPC----EMCPAQPHPCRRGFIPNIRTG 242
N CQ +G VC T C + G C + C QP+ C+ G R G
Sbjct: 266 --NHRCQ---NGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNG 320
Query: 243 A--------------CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED 288
+++D+C A G CI+ V SF C CP G + C
Sbjct: 321 GYGCVCVNGWSGDDCSENIDDC-AFASCTPGSTCIDRVASFSCMCPEG----KAGLLCHL 375
Query: 289 IDECSTIPGICEGGECTNTV---SSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTN--- 342
D C + P C G +T Y C CP G Y D T +D C A +N
Sbjct: 376 DDACISNP--CHKGALCDTNPLNGQYICTCPQG-YKGADCTEDVDE----CAMANSNPCE 428
Query: 343 --GRCSN-------QLPQSITKMQCCCDAGRCWSP-------------GVTVA--PEMCP 378
G+C N + + +C D C S G T P
Sbjct: 429 HAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKG 488
Query: 379 IRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPS 438
+ + N+ S P V G+ + PPGF GP
Sbjct: 489 VHCELEINECQSNPCVNNGQCVDKVNRFQCL-----CPPGFT-GP--------------- 527
Query: 439 REPPRVLPVNVTDYCQLVRYLCQNG-RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKN 497
V +++ D C NG +CI P C+C GF L E ++D C+ +
Sbjct: 528 -----VCQIDIDDCSSTP---CLNGAKCIDHPNGYECQCATGFTGVLCEE--NIDNCDPD 577
Query: 498 PCAGGECINNQGSYTCQCRAGYQSTLTRTECRD-IDECLQNGRICNNGRCINTDGSFHCV 556
PC G+C + SYTC C GY + C D IDEC + + N+GRCI+ + C
Sbjct: 578 PCHHGQCQDGIDSYTCICNPGYMGAI----CSDQIDECYSSPCL-NDGRCIDLVNGYQCN 632
Query: 557 CNAGFHVTRDGKNCE-DMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK-DI 614
C G G NCE + D+C+ N C++G+C++ + C+C PGF G+ C DI
Sbjct: 633 CQPG----TSGVNCEINFDDCA-SNPCIHGICMDGINRYSCVCSPGF----TGQRCNIDI 683
Query: 615 NECETPGICMNGRCVNTDGSYRCECFPG----LAVGLDGRVCVDTHMRSTCYGGYKRGQC 670
+EC + C+N +RC C G + + C GG +C
Sbjct: 684 DECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKC 743
Query: 671 I-----KPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSA--EYQALCSSGPGMTSAGSD 723
+ + V K+EC PCQ ++ Y+ C G + +
Sbjct: 744 LCDAGWVGINCEVDKNEC--------LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVN 795
Query: 724 INECALDPDI-------------------------------CPNGICENLR--------G 744
I+ECA +P + C CEN
Sbjct: 796 IDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFE 855
Query: 745 TYKCICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLK 803
+Y C+C G++ G+ C +DI+EC+ + ++G C NT GS++C CP GF +
Sbjct: 856 SYTCLCAPGWQ----GQRCTIDIDECISKPCM-NHGLCHNTQGSYMCECPPGF---SGMD 907
Query: 804 TCEDIDECESSPCIN-GVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRC 862
EDID+C ++PC N G C + +F C C T D +T E + C G C
Sbjct: 908 CEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN---GGTC 964
Query: 863 EININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVC 921
+N T K C G+ G CE +I+EC C
Sbjct: 965 SDYVNSYTCK-----------------------CQAGFD---GVHCENNINECT--ESSC 996
Query: 922 KN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDAC 980
N G CV+ SF C CP G TG CL E +E + G +R C
Sbjct: 997 FNGGTCVDGINSFSCLCPVGF----TGSFCLHEINECSSHPCLNEGTCVDGLGTYR---C 1049
Query: 981 CCSVGAAWGTEE-----CEECPMRN-------TPEYEELCPRGPGFATKEITNGKPFFKD 1028
C +G + C P +N E + LCP G A ++ N
Sbjct: 1050 SCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAA 1109
Query: 1029 INECKMIPSLCTH-GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRG-QC 1086
++ LC H G C N + C+C G+ E +DEC +P C G C
Sbjct: 1110 SRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEE---QLDECASNP--CQHGATC 1164
Query: 1087 VNTPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQ 1145
+ G + C+C GY+ NC ++DECQ P GG C + ++C CPPG
Sbjct: 1165 SDFIGGYRCECVPGYQG-----VNCEYEVDECQNQPCQ-NGGTCIDLVNHFKCSCPPG-- 1216
Query: 1146 LSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMN 1205
+ + +I++C H G+C++ IG Y C C PG+ DI+EC ++
Sbjct: 1217 -TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE---GDINEC--LS 1270
Query: 1206 GGCET----FCTNSEGSYECSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQC---TNI 1257
C + C Y C C+ F R C T +D C P + +GG C +N+
Sbjct: 1271 NPCSSEGSLDCIQLTNDYLCVCRSAFT----GRHCETFVDVCPQMPCL-NGGTCAVASNM 1325
Query: 1258 PGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFICHCDMGYSGKKG 1316
P + C C GF + +C V C G C +T C C S +
Sbjct: 1326 PDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQCVHTASGPRCFCP---SPRDC 1374
Query: 1317 KTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIK---------------- 1360
++GC + C+ G +C + C C+P + G +
Sbjct: 1375 ESGCAS-SPCQHGG-SCHPQ----RQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQ 1428
Query: 1361 -CTDLDECSNGTHMCSQHA------DCKNTMGSYRCLCKEGYTGDGFTCTDL--DECSEN 1411
C D C+ HA DC TM + C C D ++C E
Sbjct: 1429 YCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANC-----SSPLPCWDYINNQCDE- 1482
Query: 1412 LNLCGNGQCL 1421
LC +CL
Sbjct: 1483 --LCNTVECL 1490
Score = 310 bits (793), Expect = 2e-83
Identities = 283/966 (29%), Positives = 416/966 (43%), Gaps = 187/966 (19%)
Query: 1811 ECQNG-PVCQRNAECINTA-GSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHG-QCI 1866
+C++G C C+ G+ C C G+ G+ C R+ C++ N C +G C+
Sbjct: 27 QCRDGYEPCVNEGMCVTYHNGTGYCKCPEGF----LGEYCQHRDPCEK--NRCQNGGTCV 80
Query: 1867 DT--VGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRN-TIGSFNCRCNHGFILS 1923
+G C C +GF D Q R GTC + ++ C C GF
Sbjct: 81 AQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFT-- 138
Query: 1924 HNNDCIDVDECASGNGNLCRNGQCINTVGS-FQCQCNEGYEVAPDGRTC-VDINECLLEP 1981
+C D C S + C NG TV + F C+C G+ G+ C D+NEC +
Sbjct: 139 -GKECQWTDACLS---HPCANGSTCTTVANQFSCKCLTGFT----GQKCETDVNECDIPG 190
Query: 1982 RKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDID-ECVEEPEICALGTCSNT-EGSFKCL 2039
GTC NL GSY+C CP G++ + C+ + C P + GTC T + +F+C
Sbjct: 191 HCQHGGTCLNLPGSYQCQCPQGFT--GQYCDSLYVPCAPSPCVNG-GTCRQTGDFTFECN 247
Query: 2040 CPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELC 2099
C GF S+ R D C GG C + C C + G + C
Sbjct: 248 CLPGFEGSTCERNIDDCPNHRCQ---NGGVCVD----GVNTYNCRCPPQWTG-----QFC 295
Query: 2100 PTEPDEAFRQ--------ICP-----YGSGIIVG--PDDSAVDMDECKEPDVCKHGQCIN 2144
+ DE Q C YG + G DD + ++D+C CI+
Sbjct: 296 TEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
Query: 2145 TDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKN---VIGGFECTCEEGFEPGPM 2201
S+ C CP G AG C D C + NPC G + + G + CTC +G++
Sbjct: 356 RVASFSCMCPEGK--AGLLCHLDDAC-ISNPCHKGALCDTNPLNGQYICTCPQGYKGADC 412
Query: 2202 MTCEDINECAQ---NPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDC 2258
ED++ECA NP A +CVNT G++ C+C GY R D +EC D
Sbjct: 413 T--EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYA---GPRCEMDINECHS---DP 464
Query: 2259 TEKQMECKNLIGTYMCICGPGYQRRPDGEGC-VDENECQTKPGICENGRCLNTRGSYTCE 2317
+ C + IG + C+C PG++ G C ++ NECQ+ P + NG+C++ + C
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCV-NNGQCVDKVNRFQCL 519
Query: 2318 CNDGFT------------ASP--NQDECLDNREGY---CFTEVLQNMCQIGSSNRNPVTK 2360
C GFT ++P N +C+D+ GY C T +C+ N +P
Sbjct: 520 CPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDP--- 576
Query: 2361 SECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRN-GECV 2419
+ C G C+ G ++ +C G IDEC C N G C+
Sbjct: 577 -DPCHHG------QCQ----DGIDSYTCICNPGYMGAICSDQIDEC--YSSPCLNDGRCI 623
Query: 2420 NDRGSYHCICKTGYTPDITGTSC-VDLNECNQAPKPC-NFICKNTEGSYQCSCPKGYILQ 2477
+ Y C C+ P +G +C ++ ++C A PC + IC + Y C C G+
Sbjct: 624 DLVNGYQCNCQ----PGTSGVNCEINFDDC--ASNPCIHGICMDGINRYSCVCSPGFT-- 675
Query: 2478 EDGRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDN-NECTSDINLC 2535
G+ C D+DECA+ C+N + GF C CP G HH SC NEC S+ +
Sbjct: 676 --GQRCNIDIDECASNPCRKGATCINGVNGFRCICPEG--PHHPSCYSQVNECLSNPCIH 731
Query: 2536 GSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHG--CQNIIGGYRCSC 2592
G+ C + C C G+ G +CE D +EC N CQ+G C N++ GYRC+C
Sbjct: 732 GN---CTGGLSGYKCLCDAGW----VGINCEVDKNECLSNP-CQNGGTCDNLVNGYRCTC 783
Query: 2593 PQGYLQHYQWNQCVDE---NECLSAHIC----GGASCHNTLG------------------ 2627
+G+ + Y +DE N CL+ C G +CH L
Sbjct: 784 KKGF-KGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPC 842
Query: 2628 -------------SYKCMCPAGFQYEQFSGGCQDINECGSAQAPC-SYG-CSNTEGGYLC 2672
SY C+C G+Q ++ + DI+EC S PC ++G C NT+G Y+C
Sbjct: 843 ENAAVCKESPNFESYTCLCAPGWQGQRCT---IDIDECISK--PCMNHGLCHNTQGSYMC 897
Query: 2673 GCPPGY 2678
CPPG+
Sbjct: 898 ECPPGF 903
Score = 296 bits (757), Expect = 3e-79
Identities = 346/1358 (25%), Positives = 509/1358 (37%), Gaps = 291/1358 (21%)
Query: 51 DALKGPNVCGSR---YNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCT------ 101
+A + C +R Y C GW G+ C I C C+ + C
Sbjct: 307 NACQNGGTCANRNGGYGCVCVNGWS----GDDCSENI--DDCAFASCTPGSTCIDRVASF 360
Query: 102 ---CPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDH------CLCQKGYIGTHCGQPVCE- 151
CP G+ C N C G C + C C +GY G C + V E
Sbjct: 361 SCMCPEGKAGLLCHLDDACISN-PCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDEC 419
Query: 152 -----SGCLNGGRCVAPN---RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIV 203
+ C + G+CV + C C G+ GP+CE D ++ C ++ G
Sbjct: 420 AMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFT 479
Query: 204 C------TKTLCCATVGRAWGHPC---EMCPAQPHPCRRGFIPNIRTGACQ-DVDECQAI 253
C C + +PC C + + + P CQ D+D+C +
Sbjct: 480 CLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSST 539
Query: 254 PGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED-IDECSTIPGICEGGECTNTVSSYF 312
P L G CI+ +EC+C G CE+ ID C P C G+C + + SY
Sbjct: 540 PCL-NGAKCIDHPNGYECQCATGF----TGVLCEENIDNCD--PDPCHHGQCQDGIDSYT 592
Query: 313 CKCPPGFYTSPDGTRCID-VRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVT 371
C C PG+ G C D + Y L +GRC + + QC C G + GV
Sbjct: 593 CICNPGYM----GAICSDQIDECYSSPCLNDGRCID----LVNGYQCNCQPG---TSGVN 641
Query: 372 VAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPP 431
C I + + C + + G Y PGF G + +
Sbjct: 642 -----CEINFDDCASNPCIHGICMDGINRYS----------CVCSPGF-TGQRCNIDIDE 685
Query: 432 VEYLYPSREPPRVL-------------PVNVTDYCQLVRYL---CQNGRCIPTPGSCRCE 475
P R+ + P + + Y Q+ L C +G C +C
Sbjct: 686 CA-SNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCL 744
Query: 476 CNKGFQLDLRGECIDVDECEKNPCA-GGECINNQGSYTCQCRAGYQSTLTRTECRDIDEC 534
C+ G+ + + E +D +EC NPC GG C N Y C C+ G++ + +IDEC
Sbjct: 745 CDAGW-VGINCE-VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQV---NIDEC 799
Query: 535 LQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSF 594
N + N G C + + C C + GKNC+ + N C N E +F
Sbjct: 800 ASNPCL-NQGTCFDDISGYTCHCVLPY----TGKNCQTVLAPCSPNPCENAAVCKESPNF 854
Query: 595 K---CICKPGFQLASDGRYCK-DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGR 650
+ C+C PG+Q G+ C DI+EC + +G C NT GSY CEC PG + G+D
Sbjct: 855 ESYTCLCAPGWQ----GQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS-GMDCE 909
Query: 651 VCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQAL 710
+D + + C G G C+ V C C G+ CQ
Sbjct: 910 EDIDDCLANPCQNG---GSCM----DGVNTFSCLCLPG--FTGDKCQ------------- 947
Query: 711 CSSGPGMTSAGSDINECALDPDICPN-GICENLRGTYKCICNSGYEVDSTGKNCV-DINE 768
+D+NEC +P C N G C + +Y C C +G++ G +C +INE
Sbjct: 948 -----------TDMNECLSEP--CKNGGTCSDYVNSYTCKCQAGFD----GVHCENNINE 990
Query: 769 CVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCIN-GVCKNSPGS 827
C +S + G C + SF C CP GF L +I+EC S PC+N G C + G+
Sbjct: 991 CTESSCF-NGGTCVDGINSFSCLCPVGFTGSFCL---HEINECSSHPCLNEGTCVDGLGT 1046
Query: 828 FICECSSESTLDPTKT---ICIET---IKGTCWQTVIDGRCEININGATLKSQCCSSLGA 881
+ C C T +T +C + KGTC Q +SQC G
Sbjct: 1047 YRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ-------------KKAESQCLCPSGW 1093
Query: 882 AWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGM 941
A G+ C + V C SR +G E + C+ +G+C+N + CQCP G
Sbjct: 1094 A-GAYCDVPNVS--CDIAASR-RGVLVEHL--CQ------HSGVCINAGNTHYCQCPLGY 1141
Query: 942 TLDATGRICLDIRLETCFLR--YEDEECTLPIAGRHRMDACCC-----SVGAAWGTEECE 994
TG C + +L+ C C+ I G C C V + +EC+
Sbjct: 1142 ----TGSYC-EEQLDECASNPCQHGATCSDFIGGYR----CECVPGYQGVNCEYEVDECQ 1192
Query: 995 ECPMRN-------TPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNT 1047
P +N ++ CP G T G ++I++C P G+C +
Sbjct: 1193 NQPCQNGGTCIDLVNHFKCSCPPG--------TRGLLCEENIDDCARGPHCLNGGQCMDR 1244
Query: 1048 IGSFKCRCDSGFALDSEERNCTDIDECRISP-DLCGRGQCVNTPGDFECKCDEGYESGFM 1106
IG + CRC GFA ER DI+EC +P G C+ D+ C C +
Sbjct: 1245 IGGYSCRCLPGFA---GERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG--- 1298
Query: 1107 MMKNCMD-IDECQRDPLLCRGGVC---HNTEGSYRCECPPGHQLSPNISAC--IDINECE 1160
++C +D C + P L GG C N + C CPPG + S+C + + E
Sbjct: 1299 --RHCETFVDVCPQMPCL-NGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGE 1355
Query: 1161 LSAHLCPNGRCVNLIGK-------------------------YQCACNPGYH-------- 1187
H RC + Y C C P +
Sbjct: 1356 QCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
Query: 1188 ---STPDRL----FCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDID 1240
STP +C D + + C + +G +CS + +C+
Sbjct: 1416 APPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGG-DCS----LTMENPWANCSSPL 1470
Query: 1241 ECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTC 1278
C D N QC + CL +D F + KTC
Sbjct: 1471 PCWDYIN----NQCDELCNTVECL-FDNFECQGNSKTC 1503
Score = 130 bits (327), Expect = 2e-29
Identities = 112/386 (29%), Positives = 162/386 (41%), Gaps = 62/386 (16%)
Query: 2313 SYTCECNDGFTASPNQDECL--DNREGYCFTE--VLQNMCQIGSSNRNPVTKSECCCDGG 2368
++ +C DG+ N+ C+ N GYC L CQ +R+P K+ C G
Sbjct: 23 AHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ----HRDPCEKNRCQNGG- 77
Query: 2369 RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADID-----ECKVIHDVCRNGEC-VNDR 2422
C Q + K C GF G D C V G C + R
Sbjct: 78 --------TCVAQAMLG-KATCRCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSR 126
Query: 2423 GSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRS 2482
+Y C C+ G+ TG C + C P C + C C G+ G+
Sbjct: 127 DTYECTCQVGF----TGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGF----TGQK 178
Query: 2483 CK-DLDECATKQHNCQF--LCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKG 2539
C+ D++EC H CQ C+N G + C+CP GFT + D+ + C + G
Sbjct: 179 CETDVNECDIPGH-CQHGGTCLNLPGSYQCQCPQGFTGQY---CDSLYVPCAPSPCVNGG 234
Query: 2540 ICQNTPGSFT--CECQRGFSLDQTGSSCE-DVDECEGNHRCQHG--CQNIIGGYRCSCPQ 2594
C+ T G FT C C GF GS+CE ++D+C NHRCQ+G C + + Y C CP
Sbjct: 235 TCRQT-GDFTFECNCLPGFE----GSTCERNIDDCP-NHRCQNGGVCVDGVNTYNCRCPP 288
Query: 2595 GYLQHYQWNQCV-DENEC-LSAHIC-GGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINE 2651
+ + C D +EC L + C G +C N G Y C+C G+ + S ++I++
Sbjct: 289 QWTGQF----CTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCS---ENIDD 341
Query: 2652 CGSAQAPCSYGCSNTEGGYLCGCPPG 2677
C A C + + C CP G
Sbjct: 342 CAFASCTPGSTCIDRVASFSCMCPEG 367
Score = 103 bits (256), Expect = 3e-21
Identities = 89/297 (29%), Positives = 122/297 (41%), Gaps = 84/297 (28%)
Query: 123 CMNGGSCSDDH-----CLCQKGYIGTHCGQ--PVCESGCLNGGRCVAPNR-----CACTY 170
C+N G C H C C +G++G +C P ++ C NGG CVA C C
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
Query: 171 GFTGPQCERDYRTG-PCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPA-QP 228
GFTG C+ Y T PCF +S G ++ T C G C+ A
Sbjct: 95 GFTGEDCQ--YSTSHPCF--VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLS 150
Query: 229 HPCRRG---------FIPNIRTG----ACQ-DVDECQAIPGLCQ-GGNCINTVGSFECKC 273
HPC G F TG C+ DV+EC IPG CQ GG C+N GS++C+C
Sbjct: 151 HPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECD-IPGHCQHGGTCLNLPGSYQCQC 209
Query: 274 PAGHKLNEVSQKCEDI----------------------DECSTIPGI----CE------- 300
P G Q C+ + EC+ +PG CE
Sbjct: 210 PQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCP 265
Query: 301 ------GGECTNTVSSYFCKCPP---GFYTSPDGTRCIDVRPGYCYTALTNGRCSNQ 348
GG C + V++Y C+CPP G + + D C+ ++P C G C+N+
Sbjct: 266 NHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECL-LQPNACQ---NGGTCANR 318
Score = 90.1 bits (222), Expect = 3e-17
Identities = 98/384 (25%), Positives = 142/384 (36%), Gaps = 94/384 (24%)
Query: 57 NVCGSRYNAYCCP------GWKTLPGGNQCIVP-ICRHSCGDGFCSR---PNMCTCPSGQ 106
+ C + N + C G K N+C +P C+H G C C CP G
Sbjct: 157 STCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHG---GTCLNLPGSYQCQCPQGF 213
Query: 107 IAPSCGSRSIQHCNIRCMNGGSCSDD-----HCLCQKGYIGTHCGQPVCE---SGCLNGG 158
C S + C+NGG+C C C G+ G+ C + + + C NGG
Sbjct: 214 TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGG 273
Query: 159 RC---VAPNRCACTYGFTGPQCERD-----------YRTGPCFTVISNQ--MCQGQLSGI 202
C V C C +TG C D G C +C SG
Sbjct: 274 VCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGD 333
Query: 203 VCTKTL-CCATVGRAWGHPCE--------MCP-------------AQPHPCRRGFI---- 236
C++ + CA G C MCP +PC +G +
Sbjct: 334 DCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTN 393
Query: 237 ----------PNIRTGA--CQDVDEC-QAIPGLCQ-GGNCINTVGSFECKCPAGHKLNEV 282
P GA +DVDEC A C+ G C+NT G+F C+C G+
Sbjct: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGY----A 449
Query: 283 SQKCE-DIDECSTIPGICEG-GECTNTVSSYFCKCPPGFYTSPDGTRC-IDVRPGYCYTA 339
+CE DI+EC + P C+ C + + + C C PGF G C +++
Sbjct: 450 GPRCEMDINECHSDP--CQNDATCLDKIGGFTCLCMPGF----KGVHCELEINECQSNPC 503
Query: 340 LTNGRCSNQLPQSITKMQCCCDAG 363
+ NG+C ++ + + QC C G
Sbjct: 504 VNNGQCVDK----VNRFQCLCPPG 523
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 508 bits (1308), Expect = e-143
Identities = 381/1333 (28%), Positives = 553/1333 (41%), Gaps = 261/1333 (19%)
Query: 184 GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHP-CEMCPAQPHPCRRGFIPNIRTG 242
G C+ N C L + T+ CC +VG WG C CP +P P I G
Sbjct: 552 GRCYLNTVNGQCANPLLELT-TQEDCCGSVGAFWGVTLCAPCPPRPAS------PVIENG 604
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
+ +CP G+K ++ C+DI+EC T+ G+C+
Sbjct: 605 ---------------------------QLECPQGYKRLNLTH-CQDINECLTL-GLCKDA 635
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRC-----IDVRPGYCYTALTNGRCSNQLPQSITKMQ 357
EC NT SY C C PG P +RC I + G CY +L G C+ L Q ITK
Sbjct: 636 ECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQI 695
Query: 358 CCCD-AGRCWS--------PGVTVAPEMCP---------------IRATEDFNKLCSVPM 393
CCC G+ W PG E+CP +R E+ +L P
Sbjct: 696 CCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEE-EELARPPR 754
Query: 394 --------VIPGRPEYPP-------------------PPLGPIPPVLPVPPGF------- 419
+PG E P G + + P +
Sbjct: 755 EQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATT 814
Query: 420 PPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQL-VRYLCQNGRCIPTPGSCRCECNK 478
PP P+ + E + PS + L D C +C G C+ P RC C+
Sbjct: 815 PPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSP 874
Query: 479 GFQL-DLRGECIDVDECEKNPCAG-GECINNQGSYTCQCRAGY--QSTLTRTECRDIDEC 534
G+QL + C D +EC ++PC G G CIN GSY+C C GY ++ EC+DI+EC
Sbjct: 875 GYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINEC 934
Query: 535 LQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSF 594
Q G +C+ G+C NT+GS+HC C+ G+ + R G +C+D++EC C +G C+N GS+
Sbjct: 935 EQPG-VCSGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINECRHPGTCPDGRCVNSPGSY 992
Query: 595 KCI-CKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCV 653
C+ C+ G++ S C D+NEC TPG+C +G+C N +GS+RC C G V D + C
Sbjct: 993 TCLACEEGYRGQSGS--CVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQ 1050
Query: 654 DTH---MRSTCYGGYKRGQCIKPLFGAVTKSECCCASTE--YAFGEPCQPCPAQNSAEYQ 708
D R++C G C+ T+ C++ E Y E C + +
Sbjct: 1051 DVDECASRASC----PTGLCLN------TEGSFACSACENGYWVNEDGTACEDLDECAFP 1100
Query: 709 ALCSSGPGMTSAGS--------------------DINECALDPDICPNGICENLRGTYKC 748
+C SG +AGS D++EC C G C+N G+Y+C
Sbjct: 1101 GVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQC 1160
Query: 749 ICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDI 808
+C G+++ + G C D+NEC+ +G+C N+ GSF C C GF+ +C+D+
Sbjct: 1161 LCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDV 1219
Query: 809 DECESS-PCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDG--RCEIN 865
DEC ++ PC+ G C N+ GSF C C + P C++ + + + G +CE +
Sbjct: 1220 DECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENS 1279
Query: 866 INGATLKSQCCSSLGAAWGSPC---TLCQVDPICG-----------------KGYS-RIK 904
C A C C D +CG +G+
Sbjct: 1280 PGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPS 1339
Query: 905 GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPS--------------------GMTLD 944
G C D++ECE+ VC LC N GSF C C S M+
Sbjct: 1340 GWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEA 1399
Query: 945 ATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDA-CCCSVGAAWGTEECEECPMRNTPE 1003
TG C+ + + GR+ A CCC+ GA+WG + C+ CP ++ E
Sbjct: 1400 PTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWG-DACDLCPSEDSAE 1458
Query: 1004 YEELCPRGPGFATKE--ITNGKPFFKDINECKMI-PSLCTHGKCRNTIGSFKCRCDSGFA 1060
+ E+CP G G+ E T G+ + D +EC + P LC +G+C NT+ + C C+ GF
Sbjct: 1459 FSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFH 1518
Query: 1061 LDSEERNCTDIDECRISPDL-CGRGQCVNTPGDFECKCDEGYESGFMMMKNCM------- 1112
D+ + C D DEC+ DL C G+CVNT G F C C + + CM
Sbjct: 1519 YDASHKKCEDHDECQ---DLACENGECVNTEGSFHCFCSPPLTLD-LSQQRCMNSTSSTE 1574
Query: 1113 DIDECQRDPLLC----RGGVCHNTEGSYR-----CECPPGHQLSPNISACIDINECELSA 1163
D+ + +C VC +R C C G S + C E+ A
Sbjct: 1575 DLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALC-PPRSSEVYA 1633
Query: 1164 HLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC--SIMNGGCETFCTNSEGSYEC 1221
LC + + + G H P + D+ SI F N G +
Sbjct: 1634 QLCN-------VARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPF-YNYLGPEDT 1685
Query: 1222 SCQPGF----------------ALMPDQRSCTDIDECEDNPNICDGGQ------------ 1253
+P F L P + + + P +G Q
Sbjct: 1686 VPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEECGILNGCEN 1745
Query: 1254 --CTNIPGEYRCLCYDGFMASEDMKTCVDVNEC-DLN--PNICLSGTCENTKGSFICHCD 1308
C + Y C C++GF CVDVNEC DLN +C+ G CENT+GS+ CHC
Sbjct: 1746 GRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCS 1805
Query: 1309 MGYSGKKGKTGCT 1321
GY + G CT
Sbjct: 1806 PGYVAEAGPPHCT 1818
Score = 506 bits (1303), Expect = e-142
Identities = 291/817 (35%), Positives = 419/817 (51%), Gaps = 75/817 (9%)
Query: 986 AAWGTEECEECPMRNTPE-YEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKC 1044
AA T C N P+ Y +C PG+ ++ + + D NEC P G+C
Sbjct: 849 AAGATNVCGPGTCVNLPDGYRCVC--SPGY---QLHPSQAYCTDDNECLRDPCK-GKGRC 902
Query: 1045 RNTIGSFKCRCDSGFALDSE--ERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYE 1102
N +GS+ C C G+ L + + C DI+EC P +C GQC NT G + C+CD+GY
Sbjct: 903 INRVGSYSCFCYPGYTLATSGATQECQDINECE-QPGVCSGGQCTNTEGSYHCECDQGY- 960
Query: 1103 SGFMMMK-NCMDIDECQRDPLLCRGGVCHNTEGSYRC-ECPPGHQLSPNISACIDINECE 1160
M+ K +C DI+EC R P C G C N+ GSY C C G++ +C+D+NEC
Sbjct: 961 --IMVRKGHCQDINEC-RHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNEC- 1014
Query: 1161 LSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCET-FCTNSEGSY 1219
L+ +C +G+C NL G ++C+C GY T D C D+DEC+ C T C N+EGS+
Sbjct: 1015 LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA-SRASCPTGLCLNTEGSF 1073
Query: 1220 ECS-CQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL-CYDGFMASEDMKT 1277
CS C+ G+ + D +C D+DEC P +C G CTN G + C C G+ S +
Sbjct: 1074 ACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDS 1132
Query: 1278 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHA 1337
C DV+EC+ + CL G C+NT GS+ C C G+ G T C D+NEC +G +C H
Sbjct: 1133 CEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANG-TVCEDVNEC-MGEEHCAPHG 1190
Query: 1338 VCTNTAGSFKCSCSPGWIG--DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1395
C N+ GSF C C+PG++ G C D+DEC+ H C NT GS+ CLC+ G+
Sbjct: 1191 ECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGH--CVNTEGSFNCLCETGF 1248
Query: 1396 --TGDGFTCTDLDECSENLN-LCGNGQCLNAPGGYRCE--CDMGFVPSADGKACEDIDEC 1450
+ + C D+DEC + + +CG +C N+PG YRC C GF + +G C DIDEC
Sbjct: 1249 QPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDEC 1307
Query: 1451 SLPNIC-VFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGS 1508
+ +C G C N G FRC C+ G+E+ SG +C DVNEC L C + C N GS
Sbjct: 1308 ANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGS 1367
Query: 1509 YICDCPPDFELNPTRVG-CVDTRSGNCYLDIRPRGDN--------------GDTACSNEI 1553
++C C D E + G C +G + P GD+ G CS+ +
Sbjct: 1368 FLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVL 1427
Query: 1554 GVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPIT-----VILEDID 1608
G ++A CCC+ G +WG C++CP+ +++E+ +CP G+G+ P + D D
Sbjct: 1428 GRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDAD 1487
Query: 1609 ECQEL-PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTV 1667
EC PGLC G+C+NT + C C G++ + + C+D +EC+ C G C NT
Sbjct: 1488 ECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLA-CENGECVNTE 1546
Query: 1668 GNYTCICPPDYMQVNGGNNCM------------DMRRSLCYRNYYADNQTCDGELLFNMT 1715
G++ C C P CM D+ +C++ N C L + T
Sbjct: 1547 GSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKK--VTNDVCSEPLRGHRT 1604
Query: 1716 KKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQR 1752
CC + G AW++ C CP S++ +A LC R
Sbjct: 1605 TYTECCCQD-GEAWSQQCALCPPRSSEVYAQLCNVAR 1640
Score = 464 bits (1193), Expect = e-130
Identities = 367/1278 (28%), Positives = 524/1278 (41%), Gaps = 250/1278 (19%)
Query: 1471 ECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTR 1530
EC GY+ + +C D+NECL C CVNT GSY+C C P L+P+R CV +
Sbjct: 607 ECPQGYKR-LNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDK 665
Query: 1531 S-----GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCS-LGKAWGTPCE--------- 1575
+ G CY + P C+ + ++K CCCS +GKAWG+ CE
Sbjct: 666 AISMLQGLCYRSLGPG------TCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEA 719
Query: 1576 ---MCPA--------------VNTSEYKILC--PGGEGFRPN----------PITVILED 1606
+CPA + +E + L P +G R + P+ V+ +
Sbjct: 720 FREICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGALPGPAERQPLRVVTDT 779
Query: 1607 IDECQELP--GLCQGGKCINTFGSFQCRCPTGYYLN--------------EDTRVCDDVN 1650
E +P G Q G+ + T + TG + T D +
Sbjct: 780 WLEAGTIPDKGDSQAGQ-VTTSVTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLV 838
Query: 1651 ECETPGI----------CGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYY 1700
TPGI CGPGTC N Y C+C P Y C D L
Sbjct: 839 TLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECL------ 892
Query: 1701 ADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIY 1760
D G + + C C A + ++C
Sbjct: 893 RDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQ----------------------- 929
Query: 1761 TGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQR 1820
DI+EC + PGVC G C N GS+ CEC G+ K C+DI+EC++ C
Sbjct: 930 -----DINECEQ-PGVCSGGQCTNTEGSYHCECDQGYIMVRKGH-CQDINECRHPGTCP- 981
Query: 1821 NAECINTAGSYRC-DCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTG 1879
+ C+N+ GSY C C+ GYR S G C D NEC P +C+HG+C + GSF C C G
Sbjct: 982 DGRCVNSPGSYTCLACEEGYRGQS-GSCVDVNECLT-PGVCAHGKCTNLEGSFRCSCEQG 1039
Query: 1880 FKTNDDQTMCLDINEC-ERDACGNGTCRNTIGSFNCR-CNHGFILSHNND-CIDVDECAS 1936
++ D+ C D++EC R +C G C NT GSF C C +G+ ++ + C D+DECA
Sbjct: 1040 YEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF 1099
Query: 1937 GNGNLCRNGQCINTVGSFQCQ-CNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGS 1995
+C +G C NT GSF C+ C+ GY +P G +C D++EC C G C+N GS
Sbjct: 1100 PG--VCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGS 1157
Query: 1996 YRCICPPGYSLQNEK-CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2054
Y+C+CP G+ L N CED++EC+ E G C N+ GSF CLC GF + G CQ
Sbjct: 1158 YQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQ 1217
Query: 2055 DLRMSYCYAKFEGGKCSSPKSR-----------NHSKQECCCALKGEGWGDPCELCPTEP 2103
D+ GG C + + + EC + E +GDP +C T
Sbjct: 1218 DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDP--VCGTWK 1275
Query: 2104 DE----AFRQICPYGSGIIVGPDDSAVDMDECKEPDVC-KHGQCINTDGSYRCECPFGYI 2158
E ++R + G + P+ +D+DEC +C HG C NTDGS+RC C G+
Sbjct: 1276 CENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1335
Query: 2159 LA--GNECVDTDECSVGNP-CGNGTCKNVIGGFECTCEEGFEP----------------- 2198
++ G +CVD +EC + CG C+NV G F C C E
Sbjct: 1336 ISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQS 1395
Query: 2199 ---------GPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDED 2249
P T D + C+ EC C G + +C ED
Sbjct: 1396 MSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSED 1455
Query: 2250 E------CEEGKH----------------DCTEKQM---------ECKNLIGTYMCICGP 2278
C GK D E + C N + Y+C+C P
Sbjct: 1456 SAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNP 1515
Query: 2279 GYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREG- 2337
G+ + C D +ECQ CENG C+NT GS+ C C+ T +Q C+++
Sbjct: 1516 GFHYDASHKKCEDHDECQDLA--CENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSST 1573
Query: 2338 -----------YCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAF 2386
C+ +V ++C + T +ECCC G W C +CP + + +
Sbjct: 1574 EDLPDHDIHMDICWKKVTNDVCS-EPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVY 1632
Query: 2387 KKLC------------PHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYT 2434
+LC H R G D+ N G + + +
Sbjct: 1633 AQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAF- 1691
Query: 2435 PDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYI-LQEDGRSCKDLDECATKQ 2493
P+ G S D ++P + + + S+ P G+ LQ + C L+ C +
Sbjct: 1692 PNTAGHS-ADRTPILESPLQPSELQPHYVASHP-EPPAGFEGLQAE--ECGILNGCENGR 1747
Query: 2494 HNCQFLCVNTIGGFTCKCPPGF--TQHHTSCIDNNECTSDIN----LCGSKGICQNTPGS 2547
CV G+TC C GF H +C+D NEC D+N LC G C+NT GS
Sbjct: 1748 ------CVRVREGYTCDCFEGFQLDAAHMACVDVNEC-DDLNGPAVLC-VHGYCENTEGS 1799
Query: 2548 FTCECQRGFSLDQTGSSC 2565
+ C C G+ + C
Sbjct: 1800 YRCHCSPGYVAEAGPPHC 1817
Score = 457 bits (1177), Expect = e-128
Identities = 345/1075 (32%), Positives = 434/1075 (40%), Gaps = 233/1075 (21%)
Query: 1323 INECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADC 1380
I+ C GA N C N ++C CSPG+ CTD +EC C C
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDP--CKGKGRC 902
Query: 1381 KNTMGSYRCLCKEGYT----GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFV 1436
N +GSY C C GYT G C D++EC E +C GQC N G Y CECD G++
Sbjct: 903 INRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVCSGGQCTNTEGSYHCECDQGYI 961
Query: 1437 PSADGKACEDIDECSLPNICVFGTCHNLPGLFRC-ECEIGYELDRSGGNCTDVNECLDPT 1495
G C+DI+EC P C G C N PG + C CE GY G+C DVNECL P
Sbjct: 962 MVRKGH-CQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECLTPG 1018
Query: 1496 TCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGV 1555
C G C N GS+ C C +E+ GC D C+
Sbjct: 1019 VCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDE-----------------CA----- 1056
Query: 1556 GVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGE-GFRPNPITVILEDIDECQELP 1614
S+ASC P +C +NT E C E G+ N ED+DEC P
Sbjct: 1057 --SRASC----------PTGLC--LNT-EGSFACSACENGYWVNEDGTACEDLDECA-FP 1100
Query: 1615 GLCQGGKCINTFGSFQCR-CPTGYYLNEDTRVCDDVNECETP-GICGPGTCYNTVGNYTC 1672
G+C G C NT GSF C+ C GY + C+DV+ECE P C G C NTVG+Y C
Sbjct: 1101 GVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQC 1160
Query: 1673 ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKP 1732
+CP + NG ++C D C GE + C P
Sbjct: 1161 LCPQGFQLANG---------TVC-----EDVNECMGE-------EHCA-----------P 1188
Query: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCE 1792
+C + S F LC PGFV D+DEC C G C+N GSF C
Sbjct: 1189 HGEC-LNSHGSFFCLCA---PGFVSAEGGTSCQDVDECATTDP-CVGGHCVNTEGSFNCL 1243
Query: 1793 CPVGFFYNDKLLVCEDIDECQN--GPVCQRNAECINTAGSYRC--DCKPGYRFTSTGQCN 1848
C GF + + C DIDEC++ PVC +C N+ GSYRC C+PG+ G C
Sbjct: 1244 CETGFQPSPESGECVDIDECEDYGDPVCG-TWKCENSPGSYRCVLGCQPGFHMAPNGDCI 1302
Query: 1849 DRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER--DACGNGTCR 1906
D +EC SHG C +T GSF CLC GF+ + C+D+NECE CG C
Sbjct: 1303 DIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCE 1362
Query: 1907 NTIGSFNCRC---------NHGFILSHNNDCIDVDECASGNGNL------CRNGQ----- 1946
N GSF C C G + E +G+ C +GQ
Sbjct: 1363 NVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAP 1422
Query: 1947 CINTVG----SFQCQCNEGY------------------EVAPDGRTCV------------ 1972
C + +G +C C +G E+ P G+ +
Sbjct: 1423 CSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTM 1482
Query: 1973 --DINECLL-EPRKCAPGTCQNLDGSYRCICPPG--YSLQNEKCEDIDECVEEPEICALG 2027
D +EC++ P C G C N Y C+C PG Y ++KCED DEC + C G
Sbjct: 1483 YTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC--QDLACENG 1540
Query: 2028 TCSNTEGSFKCLCPEGFSLSSSGRRCQ------------DLRMSYCYAKFEGGKCSSPKS 2075
C NTEGSF C C +L S +RC D+ M C+ K CS P
Sbjct: 1541 ECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLR 1600
Query: 2076 RNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC-------------------PYGSG 2116
+ + CC GE W C LCP E + Q+C YG G
Sbjct: 1601 GHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPG 1660
Query: 2117 ------IIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPF------------GYI 2158
I GP D A + D NT G P Y+
Sbjct: 1661 PDDLHYSIYGP-DGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYV 1719
Query: 2159 L------AGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPMMTCEDINECA 2211
AG E + +EC + N C NG C V G+ C C EGF+ M C D+NEC
Sbjct: 1720 ASHPEPPAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECD 1779
Query: 2212 Q---NPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQ 2262
+LC C NT GSY C C GYV E G CT K+
Sbjct: 1780 DLNGPAVLCVHGYCENTEGSYRCHCSPGYV-------------AEAGPPHCTAKE 1821
Score = 400 bits (1028), Expect = e-110
Identities = 393/1453 (27%), Positives = 553/1453 (38%), Gaps = 249/1453 (17%)
Query: 144 HCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCER---DYRTGPCFTVISNQMCQGQLS 200
HC +PVCE C N G C P C C GF G +CE D P + ++ + +
Sbjct: 185 HCIKPVCEPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPDEEFDPQNSRLAPRRWAERSP 244
Query: 201 GIVCTKTLCCATVGRAWGHPCEMCPA-------------QPHPCRR--GFIPNIR---TG 242
+ + T+ RA + PA Q HP ++ G +R T
Sbjct: 245 NLRRSSAAGEGTLARAQPPAPQSPPAPQSPPAGTLSGLSQTHPSQQHVGLSRTVRLHPTA 304
Query: 243 ACQDVDECQAIP---GLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGIC 299
A+P GL Q V P G L E +K + + + C
Sbjct: 305 TASSQLSSNALPPGPGLEQRDGTQQAVPLEHPSSPWGLNLTEKIKKIKIVFTPTICKQTC 364
Query: 300 EGGECTNTVSS----------------------YFCKCPPGFYTSPDGTRCIDVRPGYCY 337
G C N+ YFC+ P +G RCI +C
Sbjct: 365 ARGHCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIP-----CLNGGRCIGRDECWCP 419
Query: 338 TALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDF-NKLCSV-PMVI 395
T C +PQ + GR P + + T N+L SV P ++
Sbjct: 420 ANSTGKFCHLPIPQPDRE-----PPGRGSRPRALLEAPLKQSTFTLPLSNQLASVNPSLV 474
Query: 396 PGRPEYPPPPLGPIPPVLPVPPGFPPG---------PQIPVPRPPVEYLYPSR------- 439
+PP I V V G P +P P L+ S
Sbjct: 475 KVHIHHPPEASVQIHQVAQVRGGVEEALVENSVETRPPPWLPASPGHSLWDSNNIPARSG 534
Query: 440 EPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECID-------VD 492
EPPR LP L+ GRC + +C N +L + +C V
Sbjct: 535 EPPRPLPPAAPRPRGLL------GRCYLNTVNGQC-ANPLLELTTQEDCCGSVGAFWGVT 587
Query: 493 ECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGS 552
C P + G +C GY+ L T C+DI+ECL G +C + C+NT GS
Sbjct: 588 LCAPCPPRPASPVIENGQL--ECPQGYKR-LNLTHCQDINECLTLG-LCKDAECVNTRGS 643
Query: 553 FHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC- 611
+ C C G + C S+ L G+C G C ++ C
Sbjct: 644 YLCTCRPGLMLDPSRSRCVSDKAISM----LQGLCYRSLGPGTCTLPLAQRITKQICCCS 699
Query: 612 -------KDINECETPG------ICMNG-----------------------RCVNTDGSY 635
+ +C PG IC G R G
Sbjct: 700 RVGKAWGSECEKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQR 759
Query: 636 RCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEP 695
PG A RV DT + + Q G VT S A
Sbjct: 760 SSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQA-----GQVTTS-VTHAPAWVTGNAT 813
Query: 696 CQPCPAQNSAEY---QALCSSGPGMTSAGSDINECALD-PDICPNGICENLRGTYKCICN 751
P P Q AE Q S+ +T + I+ CA ++C G C NL Y+C+C+
Sbjct: 814 TPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCS 873
Query: 752 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKT--CEDID 809
GY++ + C D NEC L G+C N GS+ C C G+ T C+DI+
Sbjct: 874 PGYQLHPSQAYCTDDNEC-LRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDIN 932
Query: 810 ECES-SPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEINING 868
ECE C G C N+ GS+ CEC + + K C + + T DGRC +N G
Sbjct: 933 ECEQPGVCSGGQCTNTEGSYHCEC-DQGYIMVRKGHCQDINECRHPGTCPDGRC-VNSPG 990
Query: 869 ATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVN 928
S C + C +GY G+ C D++EC + PGVC +G C N
Sbjct: 991 ----SYTCLA-----------------CEEGYRGQSGS-CVDVNEC-LTPGVCAHGKCTN 1027
Query: 929 TRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIA-GRHRMDACCCSVGAA 987
GSF+C C G + + + C D+ + C R C + AC
Sbjct: 1028 LEGSFRCSCEQGYEVTSDEKGCQDV--DECASR---ASCPTGLCLNTEGSFACSACENGY 1082
Query: 988 WGTEECEECPMRNTPEYEELCPRG------PGFATKEITNG-KP-----FFKDINECKMI 1035
W E+ C + + +CP G F+ K+ G +P +D++EC+
Sbjct: 1083 WVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDP 1142
Query: 1036 PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFEC 1095
S C G+C+NT+GS++C C GF L + C D++EC G+C+N+ G F C
Sbjct: 1143 QSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFC 1201
Query: 1096 KCDEGYESGFMMMKNCMDIDEC-QRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACI 1154
C G+ S +C D+DEC DP C GG C NTEGS+ C C G Q SP C+
Sbjct: 1202 LCAPGFVSA-EGGTSCQDVDECATTDP--CVGGHCVNTEGSFNCLCETGFQPSPESGECV 1258
Query: 1155 DINECE-LSAHLCPNGRCVNLIGKYQC--ACNPGYHSTPDRLFCVDIDEC-SIMNGGCET 1210
DI+ECE +C +C N G Y+C C PG+H P+ C+DIDEC + G
Sbjct: 1259 DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHG 1317
Query: 1211 FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFM 1270
FC N++GS+ C C GF + P C D++ECE +C C N+ G + CLC
Sbjct: 1318 FCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLC----- 1372
Query: 1271 ASEDMKTCVDVNECDLNP------NICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDIN 1324
+ D++ D E P ++ + T ++ C YSG+KG C+ +
Sbjct: 1373 -ASDLEE-YDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDC---YSGQKGHAPCSSV- 1426
Query: 1325 ECEIGAHNCGKHAVCTNTA--------------GSFKCSCSPG---------WIGDGIKC 1361
+G + CT A F C G W
Sbjct: 1427 ---LGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMY 1483
Query: 1362 TDLDEC-SNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGF--TCTDLDECSENLNLCGNG 1418
TD DEC G +C + C NT+ Y CLC G+ D C D DEC + C NG
Sbjct: 1484 TDADECVIFGPGLC-PNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD--LACENG 1540
Query: 1419 QCLNAPGGYRCEC 1431
+C+N G + C C
Sbjct: 1541 ECVNTEGSFHCFC 1553
Score = 389 bits (1000), Expect = e-107
Identities = 279/901 (30%), Positives = 371/901 (41%), Gaps = 186/901 (20%)
Query: 766 INECVLNSL-LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCIN-GVCKN 823
I+ C + +C G C N P + C C G+ P C D +EC PC G C N
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 824 SPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC---CSSLG 880
GS+ C C TL + GAT + Q C G
Sbjct: 905 RVGSYSCFCYPGYTLATS--------------------------GATQECQDINECEQPG 938
Query: 881 AAWGSPCTLCQ--VDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKC-QC 937
G CT + C +GY ++ C+DI+EC PG C +G CVN+ GS+ C C
Sbjct: 939 VCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECR-HPGTCPDGRCVNSPGSYTCLAC 997
Query: 938 PSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECP 997
G + C+D+ EC P C+ G E C
Sbjct: 998 EEGYRGQSGS--CVDVN-----------ECLTPGV---------CAHGKCTNLEGSFRCS 1035
Query: 998 MRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCR-CD 1056
C +G E+T+ + +D++EC S C G C NT GSF C C+
Sbjct: 1036 ----------CEQG-----YEVTSDEKGCQDVDECASRAS-CPTGLCLNTEGSFACSACE 1079
Query: 1057 SGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECK-CDEGYESGFMMMKNCMDID 1115
+G+ ++ + C D+DEC P +C G C NT G F CK CD GY + +C D+D
Sbjct: 1080 NGYWVNEDGTACEDLDECAF-PGVCPSGVCTNTAGSFSCKDCDGGYRPS-PLGDSCEDVD 1137
Query: 1116 ECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLI 1175
EC+ C GG C NT GSY+C CP G QL+ N + C D+NEC H P+G C+N
Sbjct: 1138 ECEDPQSSCLGGECKNTVGSYQCLCPQGFQLA-NGTVCEDVNECMGEEHCAPHGECLNSH 1196
Query: 1176 GKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRS 1235
G + C C PG+ S C D+DEC+ + C N+EGS+ C C+ GF P+
Sbjct: 1197 GSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGE 1256
Query: 1236 CTDIDECED-NPNICDGGQCTNIPGEYRCL--CYDGFMASEDMKTCVDVNECDLNPNICL 1292
C DIDECED +C +C N PG YRC+ C GF + + C+D++EC N +C
Sbjct: 1257 CVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPN-GDCIDIDEC-ANDTMCG 1314
Query: 1293 S-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSC- 1350
S G C+NT GSF C CD G+ C D+NECE+ CG A+C N GSF C C
Sbjct: 1315 SHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGA-ALCENVEGSFLCLCA 1373
Query: 1351 -----------------------SPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMG-- 1385
S GD +C +G HA C + +G
Sbjct: 1374 SDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQ---KGHAPCSSVLGRN 1430
Query: 1386 --SYRCLCKEGY----------------------TGDGF------------TCTDLDEC- 1408
C C +G +G G+ TD DEC
Sbjct: 1431 TTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECV 1490
Query: 1409 SENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLF 1468
LC NG+CLN GY C C+ GF A K CED DEC C G C N G F
Sbjct: 1491 IFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQ-DLACENGECVNTEGSF 1549
Query: 1469 RCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVD 1528
C C LD S C+N+ S + PD ++
Sbjct: 1550 HCFCSPPLTLDLS-----------------QQRCMNSTSS--TEDLPDHDI--------- 1581
Query: 1529 TRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKIL 1588
++DI + D G + CCC G+AW C +CP ++ Y L
Sbjct: 1582 ------HMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQL 1635
Query: 1589 C 1589
C
Sbjct: 1636 C 1636
Score = 367 bits (942), Expect = e-101
Identities = 314/1076 (29%), Positives = 428/1076 (39%), Gaps = 220/1076 (20%)
Query: 955 LETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEE----LCPR 1010
L C+L + +C P+ + CC SVGA WG C CP R E CP+
Sbjct: 551 LGRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQ 610
Query: 1011 GPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD 1070
G+ +T+ +DINEC + LC +C NT GS+ C C G LD C
Sbjct: 611 --GYKRLNLTH----CQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS 663
Query: 1071 IDECRISPDLC----GRGQCV-----NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDP 1121
+ LC G G C C G G EC++ P
Sbjct: 664 DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWG----------SECEKCP 713
Query: 1122 LLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCA 1181
L TE ++R CP GH + A DI A R G+
Sbjct: 714 L-------PGTE-AFREICPAGHGYT---YASSDIRLSMRKAEEEELARPPREQGQRSSG 762
Query: 1182 CNPGYHSTPDRLFCVDI--------DECSIMNGGCETFCTNS----EGSYECSCQP--GF 1227
PG D D+ G T T++ G+ P G
Sbjct: 763 ALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGI 822
Query: 1228 ALMPDQR--SCTDIDECEDNPNI--CDGGQCTNI---------PGEYRCLCYDGFMASED 1274
A + +++ TD+ P I C G TN+ P YRC+C G+
Sbjct: 823 AEIQEEQVTPSTDVLVTLSTPGIDRCAAG-ATNVCGPGTCVNLPDGYRCVCSPGYQLHPS 881
Query: 1275 MKTCVDVNEC--------------------------------------DLN----PNICL 1292
C D NEC D+N P +C
Sbjct: 882 QAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCS 941
Query: 1293 SGTCENTKGSFICHCDMGYSGKKGKTGCTDINEC-EIGAHNCGKHAVCTNTAGSFKC-SC 1350
G C NT+GS+ C CD GY + K C DINEC G G+ C N+ GS+ C +C
Sbjct: 942 GGQCTNTEGSYHCECDQGYIMVR-KGHCQDINECRHPGTCPDGR---CVNSPGSYTCLAC 997
Query: 1351 SPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDEC 1408
G+ G C D++EC T H C N GS+RC C++GY T D C D+DEC
Sbjct: 998 EEGYRGQSGSCVDVNECL--TPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDEC 1055
Query: 1409 SENLNLCGNGQCLNAPGGYRCE-CDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGL 1467
+ + C G CLN G + C C+ G+ + DG ACED+DEC+ P +C G C N G
Sbjct: 1056 ASRAS-CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGS 1114
Query: 1468 FRC-ECEIGYELDRSGGNCTDVNECLDP-TTCISGNCVNTPGSYICDCPPDFELNPTRVG 1525
F C +C+ GY G +C DV+EC DP ++C+ G C NT GSY C CP F+L V
Sbjct: 1115 FSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTV- 1173
Query: 1526 CVDTRSGNCYLDIRPRGD----NGDTACSNEIG-VGVSKASCCCSLGKAWGT-PCEMCPA 1579
C D P G+ +G C G V + C + + T PC
Sbjct: 1174 CEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHC 1233
Query: 1580 VNT-SEYKILCPGGEGFRPNPITVILEDIDECQEL-------------PGL------CQ- 1618
VNT + LC GF+P+P + DIDEC++ PG CQ
Sbjct: 1234 VNTEGSFNCLCE--TGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQP 1291
Query: 1619 ------------------------GGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET 1654
G C NT GSF+C C G+ ++ C DVNECE
Sbjct: 1292 GFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECEL 1351
Query: 1655 P-GICGPGTCYNTVGNYTCICPPDYMQVNG--------------------GNNCMDMRRS 1693
+CG C N G++ C+C D + + G++ R
Sbjct: 1352 MLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRM 1411
Query: 1694 LCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRP 1753
CY + C L N T+ CCC+ G +W C+ CP + EF+ +C S +
Sbjct: 1412 DCYSG-QKGHAPCSSVLGRNTTQAECCCTQ--GASWGDACDLCPSEDSAEFSEICPSGKG 1468
Query: 1754 GFVID--------IYTGLPVDIDECREI-PGVCENGVCINMVGSFRCECPVGFFYNDKLL 1804
++ +YT D DEC PG+C NG C+N V + C C GF Y+
Sbjct: 1469 YIPVEGAWTFGQTMYT----DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHK 1524
Query: 1805 VCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ--CNDRNECQEIPN 1858
CED DECQ+ + N EC+NT GS+ C C P + Q N + +++P+
Sbjct: 1525 KCEDHDECQD--LACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPD 1578
Score = 359 bits (921), Expect = 2e-98
Identities = 285/975 (29%), Positives = 402/975 (41%), Gaps = 170/975 (17%)
Query: 1839 YRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERD 1898
Y T GQC + + + C +VG+F+ + T+C
Sbjct: 555 YLNTVNGQC-----ANPLLELTTQEDCCGSVGAFWGV-----------TLCAP------- 591
Query: 1899 ACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 1958
C I + C G+ + C D++EC + LC++ +C+NT GS+ C C
Sbjct: 592 -CPPRPASPVIENGQLECPQGYKRLNLTHCQDINECLTLG--LCKDAECVNTRGSYLCTC 648
Query: 1959 NEGYEVAPDGRTCVDINECLLEPRKC----APGTCQNLDGSYR-----CICPPGYSLQNE 2009
G + P CV + C PGTC L + R C C
Sbjct: 649 RPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTC-TLPLAQRITKQICCCSRVGKAWGS 707
Query: 2010 KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFE--- 2066
+CE C L TE +F+ +CP G + + D+R+S A+ E
Sbjct: 708 ECEK----------CPL---PGTE-AFREICPAGHGYTYAS---SDIRLSMRKAEEEELA 750
Query: 2067 ----------GGKCSSPKSR---------------------NHSKQECCCALKGEGWGDP 2095
G P R + + Q W
Sbjct: 751 RPPREQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTG 810
Query: 2096 CELCPTEPDEAF-----RQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYR 2150
P P++ Q+ P + ++V +D +VC G C+N YR
Sbjct: 811 NATTPPMPEQGIAEIQEEQVTP-STDVLVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYR 869
Query: 2151 CECPFGYILAGNE--CVDTDECSVGNPC-GNGTCKNVIGGFECTCEEGF---EPGPMMTC 2204
C C GY L ++ C D +EC + +PC G G C N +G + C C G+ G C
Sbjct: 870 CVCSPGYQLHPSQAYCTDDNEC-LRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQEC 928
Query: 2205 EDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQME 2264
+DINEC Q + +C NT GSY C+C GY++ + C+D +EC +H T
Sbjct: 929 QDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVR-KGHCQDINEC---RHPGTCPDGR 984
Query: 2265 CKNLIGTYMCI-CGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFT 2323
C N G+Y C+ C GY R CVD NEC T PG+C +G+C N GS+ C C G+
Sbjct: 985 CVNSPGSYTCLACEEGY--RGQSGSCVDVNECLT-PGVCAHGKCTNLEGSFRCSCEQGYE 1041
Query: 2324 ASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGW----GPHCEICP 2379
+ ++ C D E C + C G + + C+ G W G CE
Sbjct: 1042 VTSDEKGCQDVDE--CASRA---SCPTGLCLNTEGSFACSACENGY-WVNEDGTACE--- 1092
Query: 2380 FQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHC-ICKTGYTPDIT 2438
D+DEC VC +G C N GS+ C C GY P
Sbjct: 1093 ----------------------DLDEC-AFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPL 1129
Query: 2439 GTSCVDLNECNQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ 2497
G SC D++EC C CKNT GSYQC CP+G+ L +G C+D++EC ++H
Sbjct: 1130 GDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAP 1188
Query: 2498 F-LCVNTIGGFTCKCPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQR 2554
C+N+ G F C C PGF + TSC D +EC + G G C NT GSF C C+
Sbjct: 1189 HGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVG--GHCVNTEGSFNCLCET 1246
Query: 2555 GFSLDQTGSSCEDVDECE--GNHRC-QHGCQNIIGGYRC--SCPQGYLQHYQWN-QCVDE 2608
GF C D+DECE G+ C C+N G YRC C G+ H N C+D
Sbjct: 1247 GFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGF--HMAPNGDCIDI 1304
Query: 2609 NECLSAHICGG-ASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNT 2666
+EC + +CG C NT GS++C+C GF+ C D+NEC A C C N
Sbjct: 1305 DECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1364
Query: 2667 EGGYLCGCPPGY--FRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEA--CYECKING 2722
EG +LC C + +GHC G+ E P D++ +P CY +
Sbjct: 1365 EGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTG----DHAPAPTRMDCYSGQKGH 1420
Query: 2723 YPKRGRKRRSTNETD 2737
P R+T + +
Sbjct: 1421 APCSSVLGRNTTQAE 1435
Score = 320 bits (820), Expect = 1e-86
Identities = 240/817 (29%), Positives = 339/817 (41%), Gaps = 151/817 (18%)
Query: 2014 IDECVE-EPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSS 2072
ID C +C GTC N ++C+C G+ L S C D
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTD----------------- 887
Query: 2073 PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIV-GPDDSAVDMDEC 2131
N ++ C KG+G C ++ C G + G D++EC
Sbjct: 888 ---DNECLRDPC---KGKG------RCINRVG-SYSCFCYPGYTLATSGATQECQDINEC 934
Query: 2132 KEPDVCKHGQCINTDGSYRCECPFGYILAGN-ECVDTDECSVGNPCGNGTCKNVIGGFEC 2190
++P VC GQC NT+GSY CEC GYI+ C D +EC C +G C N G + C
Sbjct: 935 EQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTC 994
Query: 2191 -TCEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDE 2248
CEEG+ G +C D+NEC P +CA +C N GS+ C C GY + D + C+D
Sbjct: 995 LACEEGYR-GQSGSCVDVNECL-TPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDV 1052
Query: 2249 DECEEGKHDCTEKQMECKNLIGTYMC-ICGPGYQRRPDGEGCVDENECQTKPGICENGRC 2307
DEC + C C N G++ C C GY DG C D +EC PG+C +G C
Sbjct: 1053 DECAS-RASCPTGL--CLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPSGVC 1108
Query: 2308 LNTRGSYTC-ECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCD 2366
NT GS++C +C+ G+ SP D C D E E Q+ C +G +N V +C C
Sbjct: 1109 TNTAGSFSCKDCDGGYRPSPLGDSCEDVDE----CEDPQSSC-LGGECKNTVGSYQCLCP 1163
Query: 2367 GG--RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA-------------------DIDE 2405
G G CE + + PHG ++G+ D+DE
Sbjct: 1164 QGFQLANGTVCE--DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDE 1221
Query: 2406 CKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC--NFICKNTE 2463
C D C G CVN GS++C+C+TG+ P CVD++EC P + C+N+
Sbjct: 1222 CATT-DPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSP 1280
Query: 2464 GSYQC--SCPKGYILQEDGRSCKDLDECATKQH-NCQFLCVNTIGGFTCKCPPGF--TQH 2518
GSY+C C G+ + +G C D+DECA C NT G F C C GF +
Sbjct: 1281 GSYRCVLGCQPGFHMAPNG-DCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPS 1339
Query: 2519 HTSCIDNNECTSDINLCGSKGICQNTPGSFTCEC---------QRGFSLDQTGSSCEDVD 2569
C+D NEC + +CG+ +C+N GSF C C Q G + +
Sbjct: 1340 GWDCVDVNECELMLAVCGA-ALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSE 1398
Query: 2570 ECEGNHR-------CQHG------CQNIIGGY----RCSCPQGYLQHYQWNQC------- 2605
G+H C G C +++G C C QG + C
Sbjct: 1399 APTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAE 1458
Query: 2606 -------------------------VDENECL--SAHICGGASCHNTLGSYKCMCPAGFQ 2638
D +EC+ +C C NT+ Y C+C GF
Sbjct: 1459 FSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFH 1518
Query: 2639 YEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGC-PPGYFRIGQGHCVSGMGMGRGN 2696
Y+ C+D +EC C G C NTEG + C C PP + Q C++
Sbjct: 1519 YDASHKKCEDHDEC--QDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDL 1576
Query: 2697 PEPPVSGEMDDNSLSPEACYECKINGYPKRGRKRRST 2733
P+ + ++ ++ + C E P RG + T
Sbjct: 1577 PDHDIHMDICWKKVTNDVCSE------PLRGHRTTYT 1607
Score = 258 bits (658), Expect = 8e-68
Identities = 267/987 (27%), Positives = 360/987 (36%), Gaps = 279/987 (28%)
Query: 51 DALKGPNVCGSR---YNAYCCPGWKTLPGG--------NQCIVPICRHSCGDGFCSRPN- 98
D KG C +R Y+ +C PG+ G N+C P C G C+
Sbjct: 894 DPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQP---GVCSGGQCTNTEG 950
Query: 99 --MCTCPSGQIAPSCGSRSIQHCNI--RCMNGGSCSDDHCL----------CQKGYIGTH 144
C C G I G HC C + G+C D C+ C++GY G
Sbjct: 951 SYHCECDQGYIMVRKG-----HCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRG-Q 1004
Query: 145 CGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQ---LSG 201
G V + CL G C A +C G CE+ Y + CQ S
Sbjct: 1005 SGSCVDVNECLTPGVC-AHGKCTNLEGSFRCSCEQGYEV-----TSDEKGCQDVDECASR 1058
Query: 202 IVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGN 261
C LC T G C A C G+ N AC+D+DEC A PG+C G
Sbjct: 1059 ASCPTGLCLNTEGSF------ACSA----CENGYWVNEDGTACEDLDEC-AFPGVCPSGV 1107
Query: 262 CINTVGSFECK-CPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSY--------- 311
C NT GSF CK C G++ + + CED+DEC C GGEC NTV SY
Sbjct: 1108 CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQ 1167
Query: 312 --------------------------------FCKCPPGFYTSPDGTRCIDVRPGYCYTA 339
FC C PGF ++ GT C DV
Sbjct: 1168 LANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDP 1227
Query: 340 LTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRP 399
G C N + C C+ G SP + E I ED+ P+ +
Sbjct: 1228 CVGGHCVN----TEGSFNCLCETGFQPSP---ESGECVDIDECEDYGD----PVCGTWKC 1276
Query: 400 EYPPPPLGPIPPVLPVPPGF---PPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLV 456
E P G VL PGF P G I + D C
Sbjct: 1277 ENSP---GSYRCVLGCQPGFHMAPNGDCIDI-----------------------DECAND 1310
Query: 457 RYLCQNGRCIPTPGSCRCECNKGFQLDLRG-ECIDVDECE--KNPCAGGECINNQGSYTC 513
+G C T GS RC C++GF++ G +C+DV+ECE C C N +GS+ C
Sbjct: 1311 TMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLC 1370
Query: 514 QCR-----------------AGYQS-----------TLTRTEC----RDIDECLQ-NGRI 540
C AG QS TR +C + C GR
Sbjct: 1371 LCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRN 1430
Query: 541 CNNGRCINTDGS----------------FHCVCNAG-FHVTRDG------KNCEDMDECS 577
C T G+ F +C +G ++ +G D DEC
Sbjct: 1431 TTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECV 1490
Query: 578 I--RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSY 635
I +C NG C+N + C+C PGF + + C+D +EC+ C NG CVNT+GS+
Sbjct: 1491 IFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLA-CENGECVNTEGSF 1549
Query: 636 RCECFPGLAVGLDGRVCV------------DTHMRSTCYGGYKRGQCIKPLFG-AVTKSE 682
C C P L + L + C+ D HM C+ C +PL G T +E
Sbjct: 1550 HCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHM-DICWKKVTNDVCSEPLRGHRTTYTE 1608
Query: 683 CCCASTEYAFGEPCQPCPAQNSAEYQALCS-------------------SGPGMTSAGSD 723
CCC E A+ + C CP ++S Y LC+ GPG D
Sbjct: 1609 CCCQDGE-AWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPG----PDD 1663
Query: 724 INECALDPDICPNGICENLRGTYKCI------CNSGYEVDST------------------ 759
++ PD P N G + +G+ D T
Sbjct: 1664 LHYSIYGPDGAP---FYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVA 1720
Query: 760 -------GKNCVDINEC-VLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC 811
G + EC +LN C+NG+C + C C +GF C D++EC
Sbjct: 1721 SHPEPPAGFEGLQAEECGILNG--CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNEC 1778
Query: 812 E--SSP---CINGVCKNSPGSFICECS 833
+ + P C++G C+N+ GS+ C CS
Sbjct: 1779 DDLNGPAVLCVHGYCENTEGSYRCHCS 1805
Score = 185 bits (470), Expect = 5e-46
Identities = 162/578 (28%), Positives = 227/578 (39%), Gaps = 123/578 (21%)
Query: 67 CCPGWKTLPGGNQCIVPICRHS--CGD-GFCSRPN---MCTCPSG-QIAPS-CGSRSIQH 118
C PG+ P G+ + C + CG GFC + C C G +I+PS +
Sbjct: 1289 CQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNE 1348
Query: 119 CNIRCMNGGSCSDDH------CLC---------QKGYIGTHC------GQPVCESGCLNG 157
C + G+ ++ CLC Q+G HC GQ + E+ G
Sbjct: 1349 CELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEG----HCRPRGAGGQSMSEAP--TG 1402
Query: 158 GRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAW 217
AP R C G G PC +V+ Q + CC T G +W
Sbjct: 1403 DHAPAPTRMDCYSGQKGH--------APCSSVLGRNTTQAE----------CCCTQGASW 1444
Query: 218 GHPCEMCPAQPH-------PCRRGFIP-----NIRTGACQDVDECQAI-PGLCQGGNCIN 264
G C++CP++ P +G+IP D DEC PGLC G C+N
Sbjct: 1445 GDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLN 1504
Query: 265 TVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPD 324
TV + C C G + +KCED DEC + CE GEC NT S+ C C P
Sbjct: 1505 TVPGYVCLCNPGFHYDASHKKCEDHDECQDLA--CENGECVNTEGSFHCFCSPPLTLDLS 1562
Query: 325 GTRCI------------DVRPGYCYTALTNGRCSNQLP-QSITKMQCCCDAGRCWSPGVT 371
RC+ D+ C+ +TN CS L T +CCC G WS
Sbjct: 1563 QQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCA 1622
Query: 372 VAPEMCPIRATEDFNKLCSVPMV-------IPGRPEYPPPPLGPIPPVLPV----PPGFP 420
+CP R++E + +LC+V + + RP Y GP P L P G P
Sbjct: 1623 ----LCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYE---YGPGPDDLHYSIYGPDGAP 1675
Query: 421 ----PGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCEC 476
GP+ VP P +P+ + D ++ Q P + E
Sbjct: 1676 FYNYLGPEDTVPEPA----FPNTAG------HSADRTPILESPLQPSELQPHYVASHPEP 1725
Query: 477 NKGFQLDLRGECIDVDECE-KNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECL 535
GF E + +EC N C G C+ + YTC C G+Q C D++EC
Sbjct: 1726 PAGF------EGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECD 1779
Query: 536 Q-NGR--ICNNGRCINTDGSFHCVCNAGFHVTRDGKNC 570
NG +C +G C NT+GS+ C C+ G+ +C
Sbjct: 1780 DLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 61.2 bits (147), Expect = 1e-08
Identities = 32/84 (38%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
Query: 2610 ECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAP---CSYG-CSN 2665
EC + C C Y C C GFQ + C D+NEC P C +G C N
Sbjct: 1736 ECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCEN 1795
Query: 2666 TEGGYLCGCPPGYF-RIGQGHCVS 2688
TEG Y C C PGY G HC +
Sbjct: 1796 TEGSYRCHCSPGYVAEAGPPHCTA 1819
Score = 58.9 bits (141), Expect = 7e-08
Identities = 60/213 (28%), Positives = 84/213 (39%), Gaps = 40/213 (18%)
Query: 2337 GYCFTEVLQNMCQIGSSNRNPV----TKSECCCDGGRGWGPH-CEICPFQGTVAF----K 2387
G C+ + C NP+ T+ +CC G WG C CP + +
Sbjct: 552 GRCYLNTVNGQCA------NPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQ 605
Query: 2388 KLCPHG--RGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDL 2445
CP G R +T+ DI+EC + +C++ ECVN RGSY C C+ G D + + CV
Sbjct: 606 LECPQGYKRLNLTHCQDINECLTL-GLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVS- 663
Query: 2446 NECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIG 2505
++A +C + G C+ P L + TKQ C G
Sbjct: 664 ---DKAISMLQGLCYRSLGPGTCTLP--------------LAQRITKQICCCSRVGKAWG 706
Query: 2506 GFTCKCP-PGFTQHHTSCIDNNECT---SDINL 2534
KCP PG C + T SDI L
Sbjct: 707 SECEKCPLPGTEAFREICPAGHGYTYASSDIRL 739
Score = 58.2 bits (139), Expect = 1e-07
Identities = 48/181 (26%), Positives = 74/181 (40%), Gaps = 27/181 (14%)
Query: 2061 CYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDP-CELCPTEPD----EAFRQICPYGS 2115
CY G+C++P ++++CC ++ G WG C CP P E + CP G
Sbjct: 554 CYLNTVNGQCANPLLELTTQEDCCGSV-GAFWGVTLCAPCPPRPASPVIENGQLECPQGY 612
Query: 2116 GIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYIL--AGNECVDTDECSVG 2173
+ D++EC +CK +C+NT GSY C C G +L + + CV S+
Sbjct: 613 KRL--NLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISM- 669
Query: 2174 NPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCP 2233
G C +G CT + + + C R +GS KCP
Sbjct: 670 ---LQGLCYRSLGPGTCTL-------------PLAQRITKQICCCSRVGKAWGSECEKCP 713
Query: 2234 V 2234
+
Sbjct: 714 L 714
Score = 56.2 bits (134), Expect = 4e-07
Identities = 28/71 (39%), Positives = 37/71 (52%), Gaps = 6/71 (8%)
Query: 2532 INLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNH----RCQHG-CQNIIG 2586
+N C G C +TC+C GF LD +C DV+EC+ + C HG C+N G
Sbjct: 1740 LNGC-ENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEG 1798
Query: 2587 GYRCSCPQGYL 2597
YRC C GY+
Sbjct: 1799 SYRCHCSPGYV 1809
Score = 52.8 bits (125), Expect = 5e-06
Identities = 48/167 (28%), Positives = 63/167 (37%), Gaps = 47/167 (28%)
Query: 1695 CYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPG 1754
CY N N C LL T++ CC S +G W TLC P
Sbjct: 554 CYLNTV--NGQCANPLLELTTQEDCCGS--VGAFWG--------------VTLCAPCPP- 594
Query: 1755 FVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQN 1814
R V ENG + ECP G+ L C+DI+EC
Sbjct: 595 ----------------RPASPVIENG---------QLECPQGY-KRLNLTHCQDINECLT 628
Query: 1815 GPVCQRNAECINTAGSYRCDCKPGYRF-TSTGQCNDRNECQEIPNIC 1860
+C ++AEC+NT GSY C C+PG S +C + +C
Sbjct: 629 LGLC-KDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLC 674
Score = 52.4 bits (124), Expect = 6e-06
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
Query: 2569 DECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLS----AHICGGASCH 2623
+EC + C++G C + GY C C +G+ CVD NEC A +C C
Sbjct: 1735 EECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCE 1794
Query: 2624 NTLGSYKCMCPAGFQYE 2640
NT GSY+C C G+ E
Sbjct: 1795 NTEGSYRCHCSPGYVAE 1811
Score = 50.8 bits (120), Expect = 2e-05
Identities = 32/110 (29%), Positives = 45/110 (40%), Gaps = 4/110 (3%)
Query: 2140 GQCINTDGSYRCECPFGYILAGNECVDTDECSVG----NPCGNGTCKNVIGGFECTCEEG 2195
G+C + +C P + +C + G PC VI + C +G
Sbjct: 552 GRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQG 611
Query: 2196 FEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMC 2245
++ + C+DINEC L CVNT GSY C C G +L R C
Sbjct: 612 YKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 661
Score = 47.0 bits (110), Expect = 3e-04
Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 27/138 (19%)
Query: 96 RPNMCTCPSGQIAPSCGSR--SIQHCNI--RCMNGGSCSDDHCLCQKG-YIGTHCGQPVC 150
RP +GQ+ G + ++ HC C+ G C D C+ +G Y+ T C
Sbjct: 595 RPASPVIENGQLECPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCT------C 648
Query: 151 ESGCL---NGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKT 207
G + + RCV+ + G C R G C ++ ++ + +C
Sbjct: 649 RPGLMLDPSRSRCVSDKAISMLQGL----CYRSLGPGTCTLPLAQRITKQ-----IC--- 696
Query: 208 LCCATVGRAWGHPCEMCP 225
CC+ VG+AWG CE CP
Sbjct: 697 -CCSRVGKAWGSECEKCP 713
Score = 38.9 bits (89), Expect = 0.074
Identities = 24/78 (30%), Positives = 30/78 (38%), Gaps = 17/78 (21%)
Query: 84 ICRHSCGDGFCSRPNMCTCPSGQIA-----------PSCGSRSIQHCNIRCMNGGSC-SD 131
IC+ +C G C+ +C G P G R I C I C+NGG C
Sbjct: 359 ICKQTCARGHCAN----SCERGDTTTLYSQGGHGHDPKSGFR-IYFCQIPCLNGGRCIGR 413
Query: 132 DHCLCQKGYIGTHCGQPV 149
D C C G C P+
Sbjct: 414 DECWCPANSTGKFCHLPI 431
Score = 37.0 bits (84), Expect = 0.28
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 15/65 (23%)
Query: 128 SCSDDHCL--CQKGYI------GTHCGQP-------VCESGCLNGGRCVAPNRCACTYGF 172
+C+ HC C++G G H P C+ CLNGGRC+ + C C
Sbjct: 363 TCARGHCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANS 422
Query: 173 TGPQC 177
TG C
Sbjct: 423 TGKFC 427
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 504 bits (1298), Expect = e-142
Identities = 303/859 (35%), Positives = 414/859 (48%), Gaps = 130/859 (15%)
Query: 1069 TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGV 1128
T+I+EC ++PD+CG G C+N P + C C EGY K C+DIDEC + LC G
Sbjct: 873 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRK-CVDIDECTQVQHLCSQGR 931
Query: 1129 CHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCA-CNPGYH 1187
C NTEGS+ C CP G S + CID++EC L +C G CVN +G ++C C+ GY
Sbjct: 932 CENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYR 990
Query: 1188 STPDRLFCVDIDECSIMNGGCETFCTNSEGSYEC-SCQPGFALMPDQRSCTDIDECEDNP 1246
T R C DIDEC + + C NS GSY+C C GF Q C D+DEC + P
Sbjct: 991 MT-QRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ--CLDVDECLE-P 1046
Query: 1247 NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICH 1306
N+C G C+N+ G Y C C+ G+ + D K C D++EC N+C++G C+NT+GSF C
Sbjct: 1047 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCT 1105
Query: 1307 CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGI--KCTDL 1364
C GY K C DI+EC+ H C H C NT GSF+C C G+ G+ C D+
Sbjct: 1106 CGQGYQLSAAKDQCEDIDECQ-HRHLCA-HGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 1163
Query: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYT-GDGFTCTDLDECSENLNLCG-NGQCLN 1422
+EC +C Q DC NT GSY C C +G+ D TC D++EC E+ LCG G+CLN
Sbjct: 1164 NECLEDKSVC-QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLN 1221
Query: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNIC-VFGTCHNLPGLFRCECEIGYELDRS 1481
G + C C GF SADG+ CEDIDEC +C G C N G FRC C G++ +
Sbjct: 1222 TEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQD 1281
Query: 1482 GGNCTDVNEC-LDPTTCISGNCVNTPGSYICDCPPDF-ELNPTRVGCVDTRSGNCYLDI- 1538
G C DVNEC L C C N GS++C C + E +P C S + +D+
Sbjct: 1282 GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1341
Query: 1539 RPRGD--------NGDTACSNEIGVGVSKASCCCSLGKAWGTPCEM--CPAVNTSEYKIL 1588
+P+ + N + C N + V+K CCC+ G WG CE+ CP + T+E+ +
Sbjct: 1342 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1401
Query: 1589 CPGGEGFRPNPITVI------LEDIDEC----QELPGLCQGGKCINTFGSFQCRCPTGYY 1638
CP G+GF P + +D DEC QE+ C+ G C+NT ++C C G Y
Sbjct: 1402 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEI---CKNGFCLNTRPGYECYCKQGTY 1458
Query: 1639 LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM---------- 1688
+ C D++EC+ P C G C NT G+Y C C + C+
Sbjct: 1459 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE 1518
Query: 1689 --DMRRSLCYRNYYADNQTCDGELLFNMTKKM-CCCSYNIGRAWNKPC------------ 1733
D+ + LC+ + +D C L+ T CCC Y G AW C
Sbjct: 1519 ETDVYQDLCWE-HLSDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCALCPLKDSDDYA 1575
Query: 1734 EQCPIPST----------------------------DEF--------ATLCG-------- 1749
+ C IP T D F A CG
Sbjct: 1576 QLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENG 1635
Query: 1750 ---SQRPGFVIDIYTGLP--------VDIDECREIPG---VCENGVCINMVGSFRCECPV 1795
+ G+ D + G VD++EC E+ +C+N CIN GS++C C
Sbjct: 1636 RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1695
Query: 1796 GFFYNDKLLVCEDIDECQN 1814
G+ +DK C ++ N
Sbjct: 1696 GYVPSDKPNYCTPLNTALN 1714
Score = 487 bits (1254), Expect = e-137
Identities = 361/1235 (29%), Positives = 522/1235 (42%), Gaps = 217/1235 (17%)
Query: 184 GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG-HPCEMCPAQPHPCRRGFIPNIRTG 242
G CF C L G+ + CC TVG +WG + C+ CP + P G+
Sbjct: 557 GRCFQETIGSQCGKALPGLSKQED-CCGTVGTSWGFNKCQKCPKK--PSYHGY------- 606
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
+ EC +PG + N C+DI+EC + G+C G
Sbjct: 607 --NQMMEC--LPGYKRVNNTF----------------------CQDINECQ-LQGVCPNG 639
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP------GYCYTALTNGR-CSNQLPQSITK 355
EC NT+ SY C C GF P + C+ P G CY +++GR C + L +TK
Sbjct: 640 ECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTK 699
Query: 356 MQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLC------SVPMVIPGRPEYPPPPLGPI 409
CCC G+ W P E CP+ T F ++C +V V RP + GP+
Sbjct: 700 QLCCCSVGKAWGPHC----EKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPV 755
Query: 410 ----PPVLPVPPGFPPGPQIPVPRPPVEYLYPSRE--------------PPRVLPVNVTD 451
PV P P +P PVE L SRE P + +P +
Sbjct: 756 FVKPKNTQPVAKSTHP-PPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQE 814
Query: 452 YCQLVRYLCQNGRCIPT-------PG--------------SCRCECNKGFQLDLRGECID 490
+L Q I T PG + + Q+ + +
Sbjct: 815 KTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTE 874
Query: 491 VDECEKNP--CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCIN 548
++EC NP C G CIN YTC C GY+ + + +C DIDEC Q +C+ GRC N
Sbjct: 875 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 934
Query: 549 TDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKC-ICKPGFQLASD 607
T+GSF C+C AGF + +G NC D+DEC ++C G C+N G+F+C C G+++
Sbjct: 935 TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR 994
Query: 608 GRYCKDINECETPGICMNGRCVNTDGSYRC----ECFPG-------LAVGLDGRVC---- 652
GR C+DI+EC P C + +CVN+ GSY+C E F G + L+ VC
Sbjct: 995 GR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD 1053
Query: 653 ---VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNS-AEYQ 708
++ +C+ GY R + C E G C +N+ ++
Sbjct: 1054 CSNLEGSYMCSCHKGYTR----------TPDHKHCRDIDECQQGNLCVNGQCKNTEGSFR 1103
Query: 709 ALCSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD 765
C G +++A DI+EC +C +G C N G+++C+C+ GY G +C D
Sbjct: 1104 CTCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED 1162
Query: 766 INECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCI--NGVCKN 823
INEC+ + +C G C NT GS+ CTCP GF D KTC+DI+ECE G C N
Sbjct: 1163 INECLEDKSVCQRGDCINTAGSYDCTCPDGF-QLDDNKTCQDINECEHPGLCGPQGECLN 1221
Query: 824 SPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAW 883
+ GSF C C ++ C E I TV D + + + C A
Sbjct: 1222 TEGSFHCVCQQGFSISADGRTC-EDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA-- 1278
Query: 884 GSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCP----- 938
P G+G C D++ECE+ GVC C N GSF C C
Sbjct: 1279 ----------PQDGQG--------CVDVNECELLSGVCGEAFCENVEGSFLCVCADENQE 1320
Query: 939 -SGMTLDATGRICLDIRLET---------CFLRYEDEE-CTLPIAGRHRMDACCCSVGAA 987
S MT R D+ ++ C+ D C +A CCC+ GA
Sbjct: 1321 YSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAG 1380
Query: 988 WGTEECE--ECPMRNTPEYEELCPRGPGFATKEITN---GKPFFKDINECKMI-PSLCTH 1041
WG + CE CP+ T E+ E+CP+G GF ++ G +KD +EC + +C +
Sbjct: 1381 WG-DNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN 1439
Query: 1042 GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFEC------ 1095
G C NT ++C C G D + C D+DEC+ P C GQCVNT G + C
Sbjct: 1440 GFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPM 1498
Query: 1096 -------KCDEGYESGFMMMKNCMDIDECQR---DPLLCRGGVCHNTEGSYRCECPPGHQ 1145
+C ES + + + D C D +C + C C G
Sbjct: 1499 VLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1558
Query: 1146 LSPNISACIDINECELSAHLC---------PNGR--CVNLIGKYQCACNPGYHSTPDRLF 1194
+ C + + + A LC P GR V+ +Y +P + DR
Sbjct: 1559 WGMQCALC-PLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADP--YFIQDRFL 1615
Query: 1195 C----VDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPN--- 1247
+ +EC I+NG C + Y C C G+ L + +C D++EC++ N
Sbjct: 1616 NSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMS 1675
Query: 1248 ICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN 1282
+C +C N G Y+CLC G++ S+ C +N
Sbjct: 1676 LCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1710
Score = 480 bits (1236), Expect = e-135
Identities = 293/879 (33%), Positives = 417/879 (47%), Gaps = 113/879 (12%)
Query: 1846 QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECE--RDACGNG 1903
Q + NEC P+IC G CI+ + C+C+ G++ ++ Q C+DI+EC + C G
Sbjct: 871 QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 930
Query: 1904 TCRNTIGSFNCRCNHGFILS-HNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQ-CNEG 1961
C NT GSF C C GF+ S +CIDVDEC ++C G C+NTVG+F+C+ C+ G
Sbjct: 931 RCENTEGSFLCICPAGFMASEEGTNCIDVDECL--RPDVCGEGHCVNTVGAFRCEYCDSG 988
Query: 1962 YEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCI-CPPGYSLQNEKCEDIDECVEE 2020
Y + GR C DI+EC L P C C N GSY+C+ C G+ N +C D+DEC+ E
Sbjct: 989 YRMTQRGR-CEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECL-E 1045
Query: 2021 PEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSK 2080
P +CA G CSN EGS+ C C +G++ + + C+D+ C +G C + + +N
Sbjct: 1046 PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI--DECQ---QGNLCVNGQCKN--- 1097
Query: 2081 QECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHG 2140
+ +FR C G + D D+DEC+ +C HG
Sbjct: 1098 ----------------------TEGSFRCTCGQGYQLSAA-KDQCEDIDECQHRHLCAHG 1134
Query: 2141 QCINTDGSYRCECPFGYILA--GNECVDTDEC-SVGNPCGNGTCKNVIGGFECTCEEGFE 2197
QC NT+GS++C C GY + G+ C D +EC + C G C N G ++CTC +GF+
Sbjct: 1135 QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 1194
Query: 2198 PGPMMTCEDINECAQNPLLCA--FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGK 2255
TC+DINEC ++P LC C+NT GS+ C C G+ + D R C+D DEC
Sbjct: 1195 LDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECV--N 1251
Query: 2256 HDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYT 2315
+ + C N G++ C+C G+Q DG+GCVD NEC+ G+C C N GS+
Sbjct: 1252 NTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFL 1311
Query: 2316 CECND-GFTASPNQDECLDNREGYCFTEVLQ-----NMCQIGSSNRN--------PVTKS 2361
C C D SP +C +V Q C ++ + VTK
Sbjct: 1312 CVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQ 1371
Query: 2362 ECCCDGGRGWGPHCEI--CPFQGTVAFKKLCPHGRGFMTNG-----------ADIDECKV 2408
ECCC G GWG +CEI CP GT F ++CP G+GF+ G D DEC +
Sbjct: 1372 ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLL 1431
Query: 2409 I-HDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQ 2467
++C+NG C+N R Y C CK G D C D++EC + C NTEGSY
Sbjct: 1432 FGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYN 1491
Query: 2468 CSCPKGYILQEDGRSC-------KDLDECATKQHNC------QFLCVNTIGG-----FTC 2509
C C +L + C + ++E Q C +++C + G C
Sbjct: 1492 CFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTEC 1551
Query: 2510 KCPPGFTQHHTSCIDNNECTSD-INLCGSKGICQNTP----------GSFTCECQRGFSL 2558
C G + + + D LC + P +T E F
Sbjct: 1552 CCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1611
Query: 2559 DQTGSSCEDV--DECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAH 2615
D+ +S E++ +EC + C++G C + GY C C GY CVD NEC +
Sbjct: 1612 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELN 1671
Query: 2616 ----ICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDIN 2650
+C A C NT GSYKC+C G+ C +N
Sbjct: 1672 NRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1710
Score = 462 bits (1189), Expect = e-129
Identities = 300/894 (33%), Positives = 415/894 (46%), Gaps = 149/894 (16%)
Query: 903 IKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRY 962
I TQ +I+EC V P +C G C+N + C C G R C+DI
Sbjct: 867 IAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI--------- 917
Query: 963 EDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNG 1022
+ECT +H CS G TE C +CP G A++E TN
Sbjct: 918 --DECTQV---QH-----LCSQGRCENTEGSFLC----------ICPAG-FMASEEGTN- 955
Query: 1023 KPFFKDINECKMIPSLCTHGKCRNTIGSFKCR-CDSGFALDSEERNCTDIDECRISPDLC 1081
D++EC + P +C G C NT+G+F+C CDSG+ + R C DIDEC ++P C
Sbjct: 956 ---CIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDEC-LNPSTC 1009
Query: 1082 GRGQCVNTPGDFEC-KCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCEC 1140
QCVN+PG ++C C EG+ C+D+DEC +P +C G C N EGSY C C
Sbjct: 1010 PDEQCVNSPGSYQCVPCTEGFRG---WNGQCLDVDECL-EPNVCANGDCSNLEGSYMCSC 1065
Query: 1141 PPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200
G+ +P+ C DI+EC+ +LC NG+C N G ++C C GY + + C DIDE
Sbjct: 1066 HKGYTRTPDHKHCRDIDECQ-QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 1124
Query: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE 1260
C + C N+EGS++C C G+ C DI+EC ++ ++C G C N G
Sbjct: 1125 CQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGS 1184
Query: 1261 YRCLCYDGFMASEDMKTCVDVNECDLNPNIC-LSGTCENTKGSFICHCDMGYSGKKGKTG 1319
Y C C DGF +D KTC D+NEC+ +P +C G C NT+GSF C C G+S
Sbjct: 1185 YDCTCPDGFQL-DDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 1242
Query: 1320 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG--DGIKCTDLDECSNGTHMCSQH 1377
C DI+EC + C H C NTAGSF+C C G+ DG C D++EC + +C +
Sbjct: 1243 CEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGE- 1300
Query: 1378 ADCKNTMGSYRCLCKEG------YTGD--GFTCTDLD-----------ECSENLN---LC 1415
A C+N GS+ C+C + TG T TDLD EC NLN LC
Sbjct: 1301 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLC 1360
Query: 1416 GNGQ---------CLNAPGGYRCECDM-------------------GFVPS------ADG 1441
N C + G+ C++ GFVP+ A G
Sbjct: 1361 DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG 1420
Query: 1442 KACEDIDECSL--PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCIS 1499
+ +D DEC L IC G C N + C C+ G D C D++EC DP++CI
Sbjct: 1421 ENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCID 1480
Query: 1500 GNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN-------CYLDIRPRGDNGDTACSNE 1552
G CVNT GSY C C L+ + C+ N Y D+ + + CS
Sbjct: 1481 GQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRP 1540
Query: 1553 -IGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILC---------PGG--------EG 1594
+G + CCC G+AWG C +CP ++ +Y LC P G E
Sbjct: 1541 LVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQ 1600
Query: 1595 FRPNPITVILED----------IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTR 1644
+ P ++D +EC L G C+ G+C+ + C C GY+L+
Sbjct: 1601 YTPEADPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKM 1659
Query: 1645 VCDDVNECE----TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSL 1694
C DVNEC+ +C C NT G+Y C+C P Y+ + N C + +L
Sbjct: 1660 TCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1713
Score = 435 bits (1119), Expect = e-121
Identities = 298/931 (32%), Positives = 406/931 (43%), Gaps = 159/931 (17%)
Query: 1593 EGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC 1652
EG+R + DIDEC ++ LC G+C NT GSF C CP G+ +E+ C DV+EC
Sbjct: 903 EGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC 962
Query: 1653 ETPGICGPGTCYNTVGNYTC-ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELL 1711
P +CG G C NTVG + C C Y G C D+ L + TC E
Sbjct: 963 LRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECL-------NPSTCPDEQC 1014
Query: 1712 FNMTKKMCCCSYNIG-RAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDEC 1770
N C G R WN C +D+DEC
Sbjct: 1015 VNSPGSYQCVPCTEGFRGWNGQC-------------------------------LDVDEC 1043
Query: 1771 REIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGS 1830
E P VC NG C N+ GS+ C C G+ C DIDECQ G +C N +C NT GS
Sbjct: 1044 LE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCV-NGQCKNTEGS 1101
Query: 1831 YRCDCKPGYRFTST-GQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMC 1889
+RC C GY+ ++ QC D +ECQ ++C+HGQC +T GSF C+C G++ + C
Sbjct: 1102 FRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC 1160
Query: 1890 LDINEC--ERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR-NGQ 1946
DINEC ++ C G C NT GS++C C GF L N C D++EC + LC G+
Sbjct: 1161 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE--HPGLCGPQGE 1218
Query: 1947 CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL 2006
C+NT GSF C C +G+ ++ DGRTC DI+EC+ + G C N GS+RC+C G+
Sbjct: 1219 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA 1278
Query: 2007 --QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCP-EGFSLSSSGRRCQ-----DLRM 2058
+ C D++EC +C C N EGSF C+C E S +C+ DL +
Sbjct: 1279 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV 1338
Query: 2059 SY---------CYAKF-EGGKCSSPKSRNHSKQECCCALKGEGWGDPCEL--CPTEPDEA 2106
CY + C + + N +KQECCC G GWGD CE+ CP
Sbjct: 1339 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCT-SGAGWGDNCEIFPCPVLGTAE 1397
Query: 2107 FRQICPYGSGII-VGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECV 2165
F ++CP G G + G S + K+ D C +L G E
Sbjct: 1398 FTEMCPKGKGFVPAGESSSEAGGENYKDADEC--------------------LLFGQEI- 1436
Query: 2166 DTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLCAF-RCVN 2223
C NG C N G+EC C++G P+ + C D++EC Q+P C +CVN
Sbjct: 1437 ----------CKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVN 1485
Query: 2224 TYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMEC-KNLIGTYMCICGPGYQR 2282
T GSY C C VL + C E E + Q C ++L Y+C
Sbjct: 1486 TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVC-------S 1538
Query: 2283 RPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTE 2342
RP EC G +C C D ++
Sbjct: 1539 RPLVGKQTTYTECCCLYGEAWGMQCA------LCPLKD--------------------SD 1572
Query: 2343 VLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTV--AFKKLCPHGRGFMTNG 2400
+C I + R + D + P + Q +F++L
Sbjct: 1573 DYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEEL----------- 1621
Query: 2401 ADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC---NQAPKPC-N 2456
+EC +++ C NG CV + Y C C GY D +CVD+NEC N C N
Sbjct: 1622 -QAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN 1679
Query: 2457 FICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2487
C NT+GSY+C C GY+ + C L+
Sbjct: 1680 AKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1710
Score = 432 bits (1112), Expect = e-120
Identities = 281/847 (33%), Positives = 384/847 (45%), Gaps = 101/847 (11%)
Query: 1237 TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTC 1296
T+I+EC NP+IC G C N+P Y C+CY+G+ SE + CVD++EC ++C G C
Sbjct: 873 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 932
Query: 1297 ENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCS-CSPGW- 1354
ENT+GSF+C C G+ + T C D++EC + CG+ C NT G+F+C C G+
Sbjct: 933 ENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGE-GHCVNTVGAFRCEYCDSGYR 990
Query: 1355 IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL-CKEGYTGDGFTCTDLDECSENLN 1413
+ +C D+DEC N + + C N+ GSY+C+ C EG+ G C D+DEC E N
Sbjct: 991 MTQRGRCEDIDECLNPSTCPDEQ--CVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP-N 1047
Query: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECE 1473
+C NG C N G Y C C G+ + D K C DIDEC N+CV G C N G FRC C
Sbjct: 1048 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG 1107
Query: 1474 IGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN 1533
GY+L + C D++EC C G C NT GS+ C C + + C D
Sbjct: 1108 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL 1167
Query: 1534 CYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILC-PGG 1592
+ RGD C N G C C G + C +N E+ LC P G
Sbjct: 1168 EDKSVCQRGD-----CINTAG----SYDCTCPDGFQLDDN-KTCQDINECEHPGLCGPQG 1217
Query: 1593 E--------------GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYY 1638
E GF + EDIDEC G C NT GSF+C C G+
Sbjct: 1218 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 1277
Query: 1639 LNEDTRVCDDVNECE-TPGICGPGTCYNTVGNYTCICP---PDYMQVNG---GNNCMDM- 1690
+D + C DVNECE G+CG C N G++ C+C +Y + G D+
Sbjct: 1278 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1337
Query: 1691 --------RRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCE--QCPIPS 1740
+ CY N D CD L N+TK+ CCC+ G W CE CP+
Sbjct: 1338 VDVDQPKEEKKECYYN-LNDASLCDNVLAPNVTKQECCCT--SGAGWGDNCEIFPCPVLG 1394
Query: 1741 TDEFATLCGSQRPGFVIDIYTGLPV------DIDECREI-PGVCENGVCINMVGSFRCEC 1793
T EF +C + GFV + D DEC +C+NG C+N + C C
Sbjct: 1395 TAEFTEMCPKGK-GFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYC 1453
Query: 1794 PVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDC-KPGYRFTSTGQC----- 1847
G +Y+ L C D+DECQ+ C + +C+NT GSY C C P S +C
Sbjct: 1454 KQGTYYDPVKLQCFDMDECQDPSSC-IDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAE 1512
Query: 1848 -NDRNECQEI-----------PNICSHGQCIDTVGSFYCLCHTG-----------FKTND 1884
N++ E ++ +CS C C G K +D
Sbjct: 1513 SNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSD 1572
Query: 1885 DQTMCLDINEC-ERDACGNGTCRNTIGSFNCRCNHGFI---LSHNNDCIDVDECASGNGN 1940
D +I R G + + + FI ++ + + +EC NG
Sbjct: 1573 DYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG- 1631
Query: 1941 LCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINEC-LLEPRK--CAPGTCQNLDGSYR 1997
C NG+C+ + C C +GY + TCVD+NEC L R C C N DGSY+
Sbjct: 1632 -CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1690
Query: 1998 CICPPGY 2004
C+C PGY
Sbjct: 1691 CLCLPGY 1697
Score = 389 bits (999), Expect = e-107
Identities = 272/941 (28%), Positives = 382/941 (40%), Gaps = 218/941 (23%)
Query: 1362 TDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLNLCGNGQ 1419
T+++EC+ +C C N Y C+C EGY + C D+DEC++ +LC G+
Sbjct: 873 TEINECTVNPDICGA-GHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR 931
Query: 1420 CLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCE-CEIGYEL 1478
C N G + C C GF+ S +G C D+DEC P++C G C N G FRCE C+ GY +
Sbjct: 932 CENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRM 991
Query: 1479 DRSGGNCTDVNECLDPTTCISGNCVNTPGSYIC-DCPPDFELNPTRVGCVDTRSGNCYLD 1537
+ G C D++ECL+P+TC CVN+PGSY C C F
Sbjct: 992 TQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF-------------------- 1030
Query: 1538 IRPRGDNGDTACSNE-IGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFR 1596
RG NG +E + V C +L E +C +G+
Sbjct: 1031 ---RGWNGQCLDVDECLEPNVCANGDCSNL-----------------EGSYMCSCHKGYT 1070
Query: 1597 PNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG 1656
P DIDECQ+ LC G+C NT GSF+C C GY L+ C+D++EC+
Sbjct: 1071 RTPDHKHCRDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH 1129
Query: 1657 ICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD-GELLFNMT 1715
+C G C NT G++ C+C Y G++C D+ L D C G+ +
Sbjct: 1130 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL------EDKSVCQRGDCINTAG 1183
Query: 1716 KKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPG 1775
C C NK C+ DI+EC E PG
Sbjct: 1184 SYDCTCPDGFQLDDNKTCQ-------------------------------DINEC-EHPG 1211
Query: 1776 VC-ENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCD 1834
+C G C+N GSF C C GF + CEDIDEC N VC + C NTAGS+RC
Sbjct: 1212 LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 1271
Query: 1835 CKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCH---------TG---FK 1881
C G++ GQ C D NEC+ + +C C + GSF C+C TG +
Sbjct: 1272 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1331
Query: 1882 TNDDQTMCLDINECERDAC-----GNGTCRNTIG----SFNCRCNHGFILSHNNDCI--- 1929
T+ D + +D + E+ C C N + C C G N +
Sbjct: 1332 TSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCP 1391
Query: 1930 ---------------------------------DVDECASGNGNLCRNGQCINTVGSFQC 1956
D DEC +C+NG C+NT ++C
Sbjct: 1392 VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYEC 1451
Query: 1957 QCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCIC--PPGYSLQNEKC--- 2011
C +G P C D++EC +P C G C N +GSY C C P ++C
Sbjct: 1452 YCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRP 1510
Query: 2012 EDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCS 2071
+ +E +EE ++ ++ LC E S + CS
Sbjct: 1511 AESNEQIEETDV------------YQDLCWEHLS--------------------DEYVCS 1538
Query: 2072 SPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC---------PYGSGIIVGPD 2122
P + CC L GE WG C LCP + + + Q+C PYG +V
Sbjct: 1539 RPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFS 1598
Query: 2123 D-------------------SAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYIL--AG 2161
+ + +EC + C++G+C+ Y C+C GY L A
Sbjct: 1599 EQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAK 1658
Query: 2162 NECVDTDECSVGNP----CGNGTCKNVIGGFECTCEEGFEP 2198
CVD +EC N C N C N G ++C C G+ P
Sbjct: 1659 MTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVP 1699
Score = 386 bits (992), Expect = e-106
Identities = 279/892 (31%), Positives = 384/892 (43%), Gaps = 162/892 (18%)
Query: 1197 DIDECSIMNGGCET-FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCT 1255
+I+EC++ C C N Y C C G+ QR C DIDEC ++C G+C
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 933
Query: 1256 NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFIC-HCDMGYS-G 1313
N G + C+C GFMASE+ C+DV+EC L P++C G C NT G+F C +CD GY
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 992
Query: 1314 KKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-SCSPGWIGDGIKCTDLDECSNGTH 1372
++G+ C DI+EC + C C N+ GS++C C+ G+ G +C D+DEC +
Sbjct: 993 QRGR--CEDIDEC-LNPSTCPDEQ-CVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PN 1047
Query: 1373 MCSQHADCKNTMGSYRCLCKEGYTG--DGFTCTDLDECSENLNLCGNGQCLNAPGGYRCE 1430
+C+ + DC N GSY C C +GYT D C D+DEC + NLC NGQC N G +RC
Sbjct: 1048 VCA-NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCT 1105
Query: 1431 CDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNE 1490
C G+ SA CEDIDEC ++C G C N G F+C C+ GY G +C D+NE
Sbjct: 1106 CGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 1165
Query: 1491 CL-DPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTAC 1549
CL D + C G+C+NT GSY C CP F+L+ + C D P+G+ C
Sbjct: 1166 CLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKT-CQDINECEHPGLCGPQGE-----C 1219
Query: 1550 SNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDE 1609
N G C C G + C EDIDE
Sbjct: 1220 LNTEG----SFHCVCQQGFSISADGRTC---------------------------EDIDE 1248
Query: 1610 CQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYNTVG 1668
C G C NT GSF+C C G+ +D + C DVNECE G+CG C N G
Sbjct: 1249 CVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEG 1308
Query: 1669 NYTCICPPDYMQVNGGNNCMDMRRSL---------------CYRNYYADNQTCDGELLFN 1713
++ C+C + + + R S CY N D CD L N
Sbjct: 1309 SFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLN-DASLCDNVLAPN 1367
Query: 1714 MTKKMCCCSYNIGRAWNKPCE--QCPIPSTDEFATLCG---------------------- 1749
+TK+ CCC+ G W CE CP+ T EF +C
Sbjct: 1368 VTKQECCCTSGAG--WGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKD 1425
Query: 1750 ------------------SQRPGFVIDIYTGL---PV-----DIDECREIPGVCENGVCI 1783
+ RPG+ G PV D+DEC++ P C +G C+
Sbjct: 1426 ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQCV 1484
Query: 1784 NMVGSFR--CECPVGFFYNDKLLVC-----EDIDECQ-----------NGPVCQRNAECI 1825
N GS+ C P+ ++K + E I+E + VC R
Sbjct: 1485 NTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGK 1544
Query: 1826 NTAGSYRCDCKPGYRFTSTGQC-----NDRNECQEIPNICSHGQCIDTVGSFYCLCHTGF 1880
T + C C G + QC D ++ ++ NI G+ +
Sbjct: 1545 QTTYT-ECCCLYGEAWGM--QCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQY 1601
Query: 1881 KTNDDQTMCLD-----INECERDACG------NGTCRNTIGSFNCRCNHGFIL-SHNNDC 1928
D D E + + CG NG C + C C G+ L + C
Sbjct: 1602 TPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC 1661
Query: 1929 IDVDECASGNG--NLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECL 1978
+DV+EC N +LC+N +CINT GS++C C GY + C +N L
Sbjct: 1662 VDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1713
Score = 383 bits (983), Expect = e-105
Identities = 282/918 (30%), Positives = 397/918 (43%), Gaps = 167/918 (18%)
Query: 698 PCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVD 757
P P + + E +S + ++INEC ++PDIC G C NL Y CIC GY
Sbjct: 849 PVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFS 908
Query: 758 STGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPC 816
+ CVDI+EC LC G+C NT GSF+C CP GF+ + C D+DEC C
Sbjct: 909 EQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVC 968
Query: 817 INGVCKNSPGSFICE-CSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATL-KSQ 874
G C N+ G+F CE C S + T +G C ID C +N +T Q
Sbjct: 969 GEGHCVNTVGAFRCEYCDSGYRM---------TQRGRCED--ID-EC---LNPSTCPDEQ 1013
Query: 875 CCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFK 934
C +S G+ PCT +G+ G QC D+DEC + P VC NG C N GS+
Sbjct: 1014 CVNSPGSYQCVPCT---------EGFRGWNG-QCLDVDEC-LEPNVCANGDCSNLEGSYM 1062
Query: 935 CQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECE 994
C C G T + C DI DE C G +C
Sbjct: 1063 CSCHKGYTRTPDHKHCRDI----------DE----------------CQQGNLCVNGQC- 1095
Query: 995 ECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCR 1054
+NT E C G G+ +++ K +DI+EC+ LC HG+CRNT GSF+C
Sbjct: 1096 ----KNT-EGSFRCTCGQGY---QLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCV 1146
Query: 1055 CDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDI 1114
CD G+ +C DI+EC +C RG C+NT G ++C C +G++ K C DI
Sbjct: 1147 CDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ--LDDNKTCQDI 1204
Query: 1115 DECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNL 1174
+EC+ L G C NTEGS+ C C G +S + C DI+EC + +G C N
Sbjct: 1205 NECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNT 1264
Query: 1175 IGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFCTNSEGSYECSC---QPGFALM 1230
G ++C C G+ + D CVD++EC +++G C E FC N EGS+ C C ++ M
Sbjct: 1265 AGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPM 1324
Query: 1231 PDQ---RSCTDIDECEDNP---------NICDGGQCTNIPG----EYRCLCYDG------ 1268
Q R+ TD+D D P N+ D C N+ + C C G
Sbjct: 1325 TGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDN 1384
Query: 1269 --------FMASEDMKTC---------------------VDVNECDL-NPNICLSGTCEN 1298
+E + C D +EC L IC +G C N
Sbjct: 1385 CEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLN 1444
Query: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCS------- 1351
T+ + C+C G K C D++EC+ +C C NT GS+ C C+
Sbjct: 1445 TRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSC-IDGQCVNTEGSYNCFCTHPMVLDA 1502
Query: 1352 -------PGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSY----RCLCKEGYTGDGF 1400
P + I+ TD+ + H+ ++ + +G C C G G
Sbjct: 1503 SEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAW-GM 1561
Query: 1401 TCT-----DLDECSENLNLCGNGQCLNAPGGYRCECDMG--FVPSADGKACED------- 1446
C D D+ ++ N+ G+ P G D + P AD +D
Sbjct: 1562 QCALCPLKDSDDYAQLCNIPVTGR--RQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFE 1619
Query: 1447 ---IDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD----PTTCIS 1499
+EC + N C G C + + C+C GY LD + C DVNEC + + C +
Sbjct: 1620 ELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN 1679
Query: 1500 GNCVNTPGSYICDCPPDF 1517
C+NT GSY C C P +
Sbjct: 1680 AKCINTDGSYKCLCLPGY 1697
Score = 315 bits (808), Expect = 3e-85
Identities = 211/621 (33%), Positives = 276/621 (44%), Gaps = 113/621 (18%)
Query: 2126 VDMDECKEPD-VCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCK 2182
VD+DEC + +C G+C NT+GS+ C CP G++ + G C+D DEC + CG G C
Sbjct: 915 VDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCV 974
Query: 2183 NVIGGFECT-CEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYEC-KCPVGYVLR 2239
N +G F C C+ G+ CEDI+EC NP C +CVN+ GSY+C C G+ R
Sbjct: 975 NTVGAFRCEYCDSGYRMTQRGRCEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGF--R 1031
Query: 2240 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
C D DEC E + C +C NL G+YMC C GY R PD + C D +ECQ +
Sbjct: 1032 GWNGQCLDVDECLE-PNVCANG--DCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-QG 1087
Query: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
+C NG+C NT GS+ C C G+ S +D+C D E +++C G RN
Sbjct: 1088 NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-----RHLCAHGQC-RNTEG 1141
Query: 2360 KSECCCDGG---RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG 2416
+C CD G G G HCE DI+EC VC+ G
Sbjct: 1142 SFQCVCDQGYRASGLGDHCE-------------------------DINECLEDKSVCQRG 1176
Query: 2417 ECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN--FICKNTEGSYQCSCPKGY 2474
+C+N GSY C C G+ D T C D+NEC P C C NTEGS+ C C +G+
Sbjct: 1177 DCINTAGSYDCTCPDGFQLDDNKT-CQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGF 1234
Query: 2475 ILQEDGRSCKDLDECATKQH-NCQFLCVNTIGGFTCKCPPGFT--QHHTSCIDNNECTSD 2531
+ DGR+C+D+DEC + C NT G F C C GF Q C+D NEC
Sbjct: 1235 SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELL 1294
Query: 2532 INLCGSKGICQNTPGSFTCEC---------QRGFSLDQTGSSCE-DVD-------ECEGN 2574
+CG + C+N GSF C C G +T + + DVD EC N
Sbjct: 1295 SGVCG-EAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 1353
Query: 2575 HRCQHGCQNIIG----------------GYRCS---------------CPQGY------- 2596
C N++ G C CP+G
Sbjct: 1354 LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGE 1413
Query: 2597 -LQHYQWNQCVDENECL--SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECG 2653
D +ECL IC C NT Y+C C G Y+ C D++EC
Sbjct: 1414 SSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1473
Query: 2654 SAQAPCSYGCSNTEGGYLCGC 2674
+ C NTEG Y C C
Sbjct: 1474 DPSSCIDGQCVNTEGSYNCFC 1494
Score = 309 bits (791), Expect = 3e-83
Identities = 283/988 (28%), Positives = 395/988 (39%), Gaps = 189/988 (19%)
Query: 1816 PVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCL 1875
P + +C T G TS G N +C + P+ + Q ++
Sbjct: 573 PGLSKQEDCCGTVG------------TSWG-FNKCQKCPKKPSYHGYNQMME-------- 611
Query: 1876 CHTGFKTNDDQTMCLDINECE-RDACGNGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDE 1933
C G+K ++ T C DINEC+ + C NG C NT+GS+ C C GF + C+
Sbjct: 612 CLPGYKRVNN-TFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 670
Query: 1934 CASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLD 1993
S C Y + GR C+ L + C
Sbjct: 671 VISEEKGPC-------------------YRLVSSGRQCMHPLSVHLTKQLCC-------- 703
Query: 1994 GSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG--R 2051
C + EKC GT +FK +CP G + SG R
Sbjct: 704 ----CSVGKAWGPHCEKCP------------LPGT-----AAFKEICPGGMGYTVSGVHR 742
Query: 2052 RCQDLRMSYCYAKFEGGKCSSPKSRN------HSKQECCCAL-----KGEGWGDPCELCP 2100
R F K + P +++ +K+E AL G G +P E+
Sbjct: 743 RRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEP-EVAT 801
Query: 2101 TEPDEAF--------------RQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTD 2146
P++ Q+ P S I + P + +++ P + +T
Sbjct: 802 APPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTS 861
Query: 2147 GSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPMMTCE 2205
+ + P V+ D C G G C N+ + C C EG+ C
Sbjct: 862 SASQVIAPTQVTEINECTVNPDIC------GAGHCINLPVRYTCICYEGYRFSEQQRKCV 915
Query: 2206 DINECAQNPLLCA-FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQME 2264
DI+EC Q LC+ RC NT GS+ C CP G++ E+ C D DEC C E
Sbjct: 916 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEG--H 972
Query: 2265 CKNLIGTYMC-ICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTC-ECNDGF 2322
C N +G + C C GY+ G C D +EC P C + +C+N+ GSY C C +GF
Sbjct: 973 CVNTVGAFRCEYCDSGYRMTQRGR-CEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF 1030
Query: 2323 TASPNQ----DECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEIC 2378
Q DECL+ N+C G + N C C G P + C
Sbjct: 1031 RGWNGQCLDVDECLE-----------PNVCANGDCS-NLEGSYMCSCHKGYTRTPDHKHC 1078
Query: 2379 PFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDIT 2438
DIDEC+ ++C NG+C N GS+ C C GY
Sbjct: 1079 ----------------------RDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAA 1115
Query: 2439 GTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ- 2497
C D++EC + C+NTEGS+QC C +GY G C+D++EC + CQ
Sbjct: 1116 KDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQR 1175
Query: 2498 FLCVNTIGGFTCKCPPGF-TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGF 2556
C+NT G + C CP GF + +C D NEC LCG +G C NT GSF C CQ+GF
Sbjct: 1176 GDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHP-GLCGPQGECLNTEGSFHCVCQQGF 1234
Query: 2557 SLDQTGSSCEDVDECEGNHRC-QHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LS 2613
S+ G +CED+DEC N C HG C N G +RC C QG+ CVD NEC L
Sbjct: 1235 SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELL 1294
Query: 2614 AHICGGASCHNTLGSYKCMC-PAGFQYEQFSGGCQ---------DINECGSAQAPCSYGC 2663
+ +CG A C N GS+ C+C +Y +G C+ D+++ + C Y
Sbjct: 1295 SGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYY-- 1352
Query: 2664 SNTEGGYLCG--CPPGYFRIGQGHCVSGMGMGRGNPE---PPVSGEMDDNSLSPEACYEC 2718
N LC P + + C SG G G N E PV G + + P
Sbjct: 1353 -NLNDASLCDNVLAPNVTK-QECCCTSGAGWG-DNCEIFPCPVLGTAEFTEMCP------ 1403
Query: 2719 KINGYPKRGRKRRSTNETDASNIEDQSE 2746
K G+ G S++E N +D E
Sbjct: 1404 KGKGFVPAG---ESSSEAGGENYKDADE 1428
Score = 149 bits (375), Expect = 5e-35
Identities = 143/557 (25%), Positives = 213/557 (38%), Gaps = 151/557 (27%)
Query: 100 CTCPSG-QIAPSCGSRSIQHCNIRCMNG--GSCSDD----HCLCQKGYIGTHCGQPVCES 152
CTCP G Q+ + + I C + G G C + HC+CQ+G+ + G+ CE
Sbjct: 1187 CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR-TCED 1245
Query: 153 --GCLNGGRCVAPN---------RCACTYGFTGPQ----------------------CE- 178
C+N C + RC C GF PQ CE
Sbjct: 1246 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCEN 1305
Query: 179 -------------RDYR--TGPC-----------------------FTVISNQMCQGQLS 200
++Y TG C + + +C L+
Sbjct: 1306 VEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLA 1365
Query: 201 GIVCTKTLCCATVGRAWGHPCEMCPA---------QPHPCRRGFIPNIRTGA------CQ 245
V TK CC T G WG CE+ P + P +GF+P + + +
Sbjct: 1366 PNV-TKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYK 1424
Query: 246 DVDECQAI-PGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC 304
D DEC +C+ G C+NT +EC C G + V +C D+DEC P C G+C
Sbjct: 1425 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQC 1483
Query: 305 TNTVSSYFCKCPPGFYTSPDGTRCI------------DVRPGYCYTALTNGR-CSNQL-P 350
NT SY C C RCI DV C+ L++ CS L
Sbjct: 1484 VNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVG 1543
Query: 351 QSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIP 410
+ T +CCC G W G+ A +CP++ ++D+ +LC++P + GR +
Sbjct: 1544 KQTTYTECCCLYGEAW--GMQCA--LCPLKDSDDYAQLCNIP--VTGRRQ---------- 1587
Query: 411 PVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQL------VRYLCQNGR 464
P G V E P +P + + + +L + C+NGR
Sbjct: 1588 ---------PYGRDALVDFS--EQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR 1636
Query: 465 CIPTPGSCRCECNKGFQLD-LRGECIDVDECEK-----NPCAGGECINNQGSYTCQCRAG 518
C+ C+C G+ LD + C+DV+EC++ + C +CIN GSY C C G
Sbjct: 1637 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1696
Query: 519 YQSTLTRTECRDIDECL 535
Y + C ++ L
Sbjct: 1697 YVPSDKPNYCTPLNTAL 1713
Score = 145 bits (366), Expect = 6e-34
Identities = 140/544 (25%), Positives = 200/544 (36%), Gaps = 150/544 (27%)
Query: 57 NVCGSRYNAYCCPGWKTLPGG----NQCIVPICRHSCGDGFCSRPN---MCTCPSGQIAP 109
N GS C G++ G ++C+ P + C +G CS MC+C G
Sbjct: 1016 NSPGSYQCVPCTEGFRGWNGQCLDVDECLEP---NVCANGDCSNLEGSYMCSCHKGY--- 1069
Query: 110 SCGSRSIQHCNIR----CMNGGSCSDDHCLCQKGYIGTHCGQ----PVCESGCLNGGRC- 160
+R+ H + R C G C + C +G CGQ + C + C
Sbjct: 1070 ---TRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ 1126
Query: 161 ----VAPNRCACTYGFTGPQCERDYRTGPCFTVISN-QMCQGQLSGIVCTKTLCCATVGR 215
A +C T G C++ YR + C S VC + C T G
Sbjct: 1127 HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKS--VCQRGDCINTAG- 1183
Query: 216 AWGHPCEMCPAQPHPCRRGF-IPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKC 273
+ C C GF + + +T CQD++EC+ PGLC G C+NT GSF C C
Sbjct: 1184 --SYDCT--------CPDGFQLDDNKT--CQDINECEH-PGLCGPQGECLNTEGSFHCVC 1230
Query: 274 PAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVR- 332
G ++ + CEDIDEC G C NT S+ C C GF DG C+DV
Sbjct: 1231 QQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNE 1290
Query: 333 ----PGYC----------------------YTALTNGRC--------------------- 345
G C Y+ +T G+C
Sbjct: 1291 CELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT-GQCRSRTSTDLDVDVDQPKEEKKE 1349
Query: 346 -----------SNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMV 394
N L ++TK +CCC +G W + P CP+ T +F ++C
Sbjct: 1350 CYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFP--CPVLGTAEFTEMC----- 1402
Query: 395 IPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQ 454
P GF P + Y D C
Sbjct: 1403 -------------------PKGKGFVPAGESSSEAGGENY-------------KDADECL 1430
Query: 455 LV-RYLCQNGRCIPTPGSCRCECNKGFQLD-LRGECIDVDEC-EKNPCAGGECINNQGSY 511
L + +C+NG C+ T C C +G D ++ +C D+DEC + + C G+C+N +GSY
Sbjct: 1431 LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSY 1490
Query: 512 TCQC 515
C C
Sbjct: 1491 NCFC 1494
Score = 125 bits (315), Expect = 5e-28
Identities = 66/216 (30%), Positives = 102/216 (47%), Gaps = 19/216 (8%)
Query: 833 SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWG-SPCTLCQ 891
S + + + +T G C+Q I +C + G + + CC ++G +WG + C C
Sbjct: 539 SHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCP 598
Query: 892 VDPI---------CGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMT 942
P C GY R+ T C+DI+EC++ GVC NG C+NT GS++C C G
Sbjct: 599 KKPSYHGYNQMMECLPGYKRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFG 657
Query: 943 LDATGRIC------LDIRLETCF-LRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEE 995
D T C + C+ L +C P++ CCCSVG AWG CE+
Sbjct: 658 PDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWG-PHCEK 716
Query: 996 CPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
CP+ T ++E+CP G G+ + +P + +
Sbjct: 717 CPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGK 752
Score = 120 bits (300), Expect = 3e-26
Identities = 101/375 (26%), Positives = 138/375 (36%), Gaps = 90/375 (24%)
Query: 56 PNVCGS--------RYNAYCCPGWKTLPGGNQCI-VPIC---RHSCGDGFCSRPN---MC 100
P++CG+ RY C G++ +C+ + C +H C G C +C
Sbjct: 882 PDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLC 941
Query: 101 TCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCL----------CQKGYIGTHCGQPVC 150
CP+G +A G+ I C+ C + HC+ C GY T G+
Sbjct: 942 ICPAGFMASEEGTNCIDVDE--CLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED 999
Query: 151 ESGCLNGGRCVAPNRCA----------CTYGFTG--PQC--------ERDYRTGPCFTVI 190
CLN C +C CT GF G QC G C +
Sbjct: 1000 IDECLNPSTC-PDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLE 1058
Query: 191 SNQMCQGQLS------------------GIVCTKTLCCATVGRAWGHPCEMCPAQPHPCR 232
+ MC G +C C T G C C
Sbjct: 1059 GSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG---SFRCT--------CG 1107
Query: 233 RGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDEC 292
+G+ + C+D+DECQ LC G C NT GSF+C C G++ + + CEDI+EC
Sbjct: 1108 QGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 1166
Query: 293 STIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV----RPGYCYTALTNGRCSNQ 348
+C+ G+C NT SY C CP GF D C D+ PG C G C N
Sbjct: 1167 LEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCG---PQGECLN- 1221
Query: 349 LPQSITKMQCCCDAG 363
+ C C G
Sbjct: 1222 ---TEGSFHCVCQQG 1233
Score = 97.4 bits (241), Expect = 2e-19
Identities = 51/131 (38%), Positives = 67/131 (51%), Gaps = 12/131 (9%)
Query: 1471 ECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCV--- 1527
EC GY+ + C D+NEC C +G C+NT GSY C C F +PT CV
Sbjct: 611 ECLPGYKRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDP 669
Query: 1528 ---DTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSE 1584
G CY R + C + + V ++K CCCS+GKAWG CE CP T+
Sbjct: 670 PVISEEKGPCY-----RLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAA 724
Query: 1585 YKILCPGGEGF 1595
+K +CPGG G+
Sbjct: 725 FKEICPGGMGY 735
Score = 89.7 bits (221), Expect = 4e-17
Identities = 51/161 (31%), Positives = 75/161 (46%), Gaps = 28/161 (17%)
Query: 1613 LPGLCQGGKCINTFGSF----QC-RCPT-----GY---------YLNEDTRVCDDVNECE 1653
LPGL + C T G+ +C +CP GY Y + C D+NEC+
Sbjct: 572 LPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQ 631
Query: 1654 TPGICGPGTCYNTVGNYTCIC------PPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD 1707
G+C G C NT+G+Y C C P + + + CYR + + C
Sbjct: 632 LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYR-LVSSGRQCM 690
Query: 1708 GELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLC 1748
L ++TK++CCCS +G+AW CE+CP+P T F +C
Sbjct: 691 HPLSVHLTKQLCCCS--VGKAWGPHCEKCPLPGTAAFKEIC 729
Score = 86.7 bits (213), Expect = 3e-16
Identities = 61/196 (31%), Positives = 84/196 (42%), Gaps = 34/196 (17%)
Query: 1933 ECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCA-PGTCQN 1991
+C L + C TVG T N+C P+K + G Q
Sbjct: 567 QCGKALPGLSKQEDCCGTVG-----------------TSWGFNKCQKCPKKPSYHGYNQM 609
Query: 1992 LDGSYRCICPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 2050
++ C PGY + N C+DI+EC + +C G C NT GS++C C GF +
Sbjct: 610 ME------CLPGYKRVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTF 662
Query: 2051 RRCQ------DLRMSYCYAKFEGGK-CSSPKSRNHSKQECCCALKGEGWGDPCELCPTEP 2103
C CY G+ C P S + +KQ CCC++ G+ WG CE CP
Sbjct: 663 SSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV-GKAWGPHCEKCPLPG 721
Query: 2104 DEAFRQICPYGSGIIV 2119
AF++ICP G G V
Sbjct: 722 TAAFKEICPGGMGYTV 737
Score = 78.2 bits (191), Expect = 1e-13
Identities = 38/116 (32%), Positives = 64/116 (55%), Gaps = 6/116 (5%)
Query: 954 RLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPE-YEELCPRGP 1012
+L CF +C + G + + CC +VG +WG +C++CP + + Y ++ P
Sbjct: 555 QLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 614
Query: 1013 GFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNC 1068
G+ K + N F +DINEC+ + +C +G+C NT+GS++C C GF D +C
Sbjct: 615 GY--KRVNN--TFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 665
Score = 72.0 bits (175), Expect = 8e-12
Identities = 65/199 (32%), Positives = 85/199 (42%), Gaps = 39/199 (19%)
Query: 2337 GYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPH-CEICP----FQGTVAFKKLCP 2391
G CF E + + C G + + +CC G WG + C+ CP + G + P
Sbjct: 557 GRCFQETIGSQC--GKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 614
Query: 2392 -HGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCV-DLNECN 2449
+ R T DI+EC+ + VC NGEC+N GSY C CK G+ PD T +SCV D +
Sbjct: 615 GYKRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 673
Query: 2450 QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSC-KDLDECATKQHNCQFLCVNTIG--- 2505
+ PC Y L GR C L TKQ LC ++G
Sbjct: 674 EEKGPC------------------YRLVSSGRQCMHPLSVHLTKQ-----LCCCSVGKAW 710
Query: 2506 GFTC-KCP-PGFTQHHTSC 2522
G C KCP PG C
Sbjct: 711 GPHCEKCPLPGTAAFKEIC 729
Score = 66.6 bits (161), Expect = 3e-10
Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 2057 RMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWG-DPCELCPTEPD-EAFRQICPYG 2114
++ C+ + G +C SKQE CC G WG + C+ CP +P + Q+
Sbjct: 555 QLGRCFQETIGSQCGKALP-GLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECL 613
Query: 2115 SGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGY 2157
G + D++EC+ VC +G+C+NT GSYRC C G+
Sbjct: 614 PGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 656
Score = 58.2 bits (139), Expect = 1e-07
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 35 KETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDG-F 93
+ET++ R L+G NVCG R CC GW PG +C P C C +G
Sbjct: 145 QETQSGGGSRLQVHQKQQLQGVNVCGGR----CCHGWSKAPGSQRCTKPSCVPPCQNGGM 200
Query: 94 CSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGS 128
C RP +C C G +C + + Q + G S
Sbjct: 201 CLRPQLCVCKPGTKGKACETIAAQDTSSPVFGGQS 235
Score = 57.0 bits (136), Expect = 3e-07
Identities = 36/90 (40%), Positives = 46/90 (51%), Gaps = 15/90 (16%)
Query: 147 QPVCESG-CLNGGRCVAPNRCACTYGF----TGPQCERD-----YRTGPCFTVISN-QMC 195
Q VC +G CLN + RC C GF T C D GPC+ ++S+ + C
Sbjct: 633 QGVCPNGECLN---TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQC 689
Query: 196 QGQLSGIVCTKTLCCATVGRAWGHPCEMCP 225
LS + TK LCC +VG+AWG CE CP
Sbjct: 690 MHPLS-VHLTKQLCCCSVGKAWGPHCEKCP 718
Score = 55.5 bits (132), Expect = 8e-07
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Query: 1708 GELLFNMTKKMCCCSYNIGRAWN-KPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVD 1766
G+ L ++K+ CC +G +W C++CP + PG+ + D
Sbjct: 569 GKALPGLSKQEDCCG-TVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK-RVNNTFCQD 626
Query: 1767 IDECREIPGVCENGVCINMVGSFRCECPVGF 1797
I+EC ++ GVC NG C+N +GS+RC C +GF
Sbjct: 627 INEC-QLQGVCPNGECLNTMGSYRCTCKIGF 656
Score = 49.3 bits (116), Expect = 5e-05
Identities = 21/34 (61%), Positives = 25/34 (73%), Gaps = 1/34 (2%)
Query: 1806 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGY 1839
C+DI+ECQ VC N EC+NT GSYRC CK G+
Sbjct: 624 CQDINECQLQGVCP-NGECLNTMGSYRCTCKIGF 656
Score = 45.4 bits (106), Expect = 8e-04
Identities = 40/161 (24%), Positives = 57/161 (35%), Gaps = 11/161 (6%)
Query: 2140 GQCINTDGSYRCECPFGYILAGNECVDTDECSVG-NPCGNGTCKNVIGGFE--CTCEEGF 2196
G+C +C + +C T S G N C K G+ C G+
Sbjct: 557 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 616
Query: 2197 EPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMC-KDEDECEEGK 2255
+ C+DINEC + C+NT GSY C C +G+ C D E K
Sbjct: 617 KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEK 676
Query: 2256 HDC---TEKQMECKNLIGTY----MCICGPGYQRRPDGEGC 2289
C +C + + + +C C G P E C
Sbjct: 677 GPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKC 717
Score = 45.4 bits (106), Expect = 8e-04
Identities = 37/127 (29%), Positives = 49/127 (38%), Gaps = 17/127 (13%)
Query: 2542 QNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQ--------HGCQNIIGGYRCSCP 2593
Q T GS + G S + C V G ++CQ HG ++ C
Sbjct: 561 QETIGSQCGKALPGLSKQE--DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM-----ECL 613
Query: 2594 QGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYE-QFSGGCQDINEC 2652
GY + C D NEC +C C NT+GSY+C C GF + FS D
Sbjct: 614 PGY-KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 672
Query: 2653 GSAQAPC 2659
+ PC
Sbjct: 673 SEEKGPC 679
Score = 45.1 bits (105), Expect = 0.001
Identities = 45/181 (24%), Positives = 60/181 (33%), Gaps = 16/181 (8%)
Query: 3 RGRLLEIALGFTVLLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSR 62
R R +AL +S + GA + G V R R + GG L+ P
Sbjct: 50 RSRTFNVALNARYSRSSAAA-GAPSRASPG-VPSERTRRTSKPGGAALQGLRPPPPPPPE 107
Query: 63 YNAYCCPGWKTLP--GGNQCIVPICRHSCGDGFCSRPNMCTCPSG---QIAPSCGSRSIQ 117
PG + P GG+ P + P G Q+ + +
Sbjct: 108 PARPAVPGGQLHPNPGGHPAAAPFTKQGRQVVRSKVPQETQSGGGSRLQVHQKQQLQGVN 167
Query: 118 HCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQC 177
C RC +G S K C +P C C NGG C+ P C C G G C
Sbjct: 168 VCGGRCCHGWS---------KAPGSQRCTKPSCVPPCQNGGMCLRPQLCVCKPGTKGKAC 218
Query: 178 E 178
E
Sbjct: 219 E 219
Score = 41.2 bits (95), Expect = 0.015
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 1278 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC 1320
C D+NEC L +C +G C NT GS+ C C +G+ + C
Sbjct: 624 CQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 665
Score = 39.3 bits (90), Expect = 0.057
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 19/75 (25%)
Query: 119 CNIRCMNGGSCSDDHCLCQKGYIGTHCGQP---------------VCESGCLNGGRCVAP 163
C + C G SC + C+KG T + +C C+NGG+C +
Sbjct: 361 CKVTCTKG-SCQNS---CEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSR 416
Query: 164 NRCACTYGFTGPQCE 178
++C C FTG C+
Sbjct: 417 DKCQCPPNFTGKLCQ 431
Score = 37.4 bits (85), Expect = 0.22
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 1307 CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW 1354
C GY + T C DINEC++ + C NT GS++C+C G+
Sbjct: 612 CLPGYK-RVNNTFCQDINECQL--QGVCPNGECLNTMGSYRCTCKIGF 656
Score = 35.8 bits (81), Expect = 0.63
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 12/73 (16%)
Query: 2452 PKPCNFICKNTEGSYQCSCPKGY---ILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFT 2508
P C C T+GS Q SC KG ++ E+G + L + C C+N GG
Sbjct: 358 PSICKVTC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMN--GGQC 413
Query: 2509 -----CKCPPGFT 2516
C+CPP FT
Sbjct: 414 SSRDKCQCPPNFT 426
>gi|46249412 latent transforming growth factor beta binding protein 1
isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 504 bits (1298), Expect = e-142
Identities = 303/859 (35%), Positives = 414/859 (48%), Gaps = 130/859 (15%)
Query: 1069 TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGV 1128
T+I+EC ++PD+CG G C+N P + C C EGY K C+DIDEC + LC G
Sbjct: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRK-CVDIDECTQVQHLCSQGR 605
Query: 1129 CHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCA-CNPGYH 1187
C NTEGS+ C CP G S + CID++EC L +C G CVN +G ++C C+ GY
Sbjct: 606 CENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYR 664
Query: 1188 STPDRLFCVDIDECSIMNGGCETFCTNSEGSYEC-SCQPGFALMPDQRSCTDIDECEDNP 1246
T R C DIDEC + + C NS GSY+C C GF Q C D+DEC + P
Sbjct: 665 MT-QRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ--CLDVDECLE-P 720
Query: 1247 NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICH 1306
N+C G C+N+ G Y C C+ G+ + D K C D++EC N+C++G C+NT+GSF C
Sbjct: 721 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCT 779
Query: 1307 CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGI--KCTDL 1364
C GY K C DI+EC+ H C H C NT GSF+C C G+ G+ C D+
Sbjct: 780 CGQGYQLSAAKDQCEDIDECQ-HRHLCA-HGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 837
Query: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYT-GDGFTCTDLDECSENLNLCG-NGQCLN 1422
+EC +C Q DC NT GSY C C +G+ D TC D++EC E+ LCG G+CLN
Sbjct: 838 NECLEDKSVC-QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLN 895
Query: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNIC-VFGTCHNLPGLFRCECEIGYELDRS 1481
G + C C GF SADG+ CEDIDEC +C G C N G FRC C G++ +
Sbjct: 896 TEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQD 955
Query: 1482 GGNCTDVNEC-LDPTTCISGNCVNTPGSYICDCPPDF-ELNPTRVGCVDTRSGNCYLDI- 1538
G C DVNEC L C C N GS++C C + E +P C S + +D+
Sbjct: 956 GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD 1015
Query: 1539 RPRGD--------NGDTACSNEIGVGVSKASCCCSLGKAWGTPCEM--CPAVNTSEYKIL 1588
+P+ + N + C N + V+K CCC+ G WG CE+ CP + T+E+ +
Sbjct: 1016 QPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM 1075
Query: 1589 CPGGEGFRPNPITVI------LEDIDEC----QELPGLCQGGKCINTFGSFQCRCPTGYY 1638
CP G+GF P + +D DEC QE+ C+ G C+NT ++C C G Y
Sbjct: 1076 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEI---CKNGFCLNTRPGYECYCKQGTY 1132
Query: 1639 LNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM---------- 1688
+ C D++EC+ P C G C NT G+Y C C + C+
Sbjct: 1133 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE 1192
Query: 1689 --DMRRSLCYRNYYADNQTCDGELLFNMTKKM-CCCSYNIGRAWNKPC------------ 1733
D+ + LC+ + +D C L+ T CCC Y G AW C
Sbjct: 1193 ETDVYQDLCWE-HLSDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCALCPLKDSDDYA 1249
Query: 1734 EQCPIPST----------------------------DEF--------ATLCG-------- 1749
+ C IP T D F A CG
Sbjct: 1250 QLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENG 1309
Query: 1750 ---SQRPGFVIDIYTGLP--------VDIDECREIPG---VCENGVCINMVGSFRCECPV 1795
+ G+ D + G VD++EC E+ +C+N CIN GS++C C
Sbjct: 1310 RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLP 1369
Query: 1796 GFFYNDKLLVCEDIDECQN 1814
G+ +DK C ++ N
Sbjct: 1370 GYVPSDKPNYCTPLNTALN 1388
Score = 487 bits (1254), Expect = e-137
Identities = 361/1235 (29%), Positives = 522/1235 (42%), Gaps = 217/1235 (17%)
Query: 184 GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG-HPCEMCPAQPHPCRRGFIPNIRTG 242
G CF C L G+ + CC TVG +WG + C+ CP + P G+
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQED-CCGTVGTSWGFNKCQKCPKK--PSYHGY------- 280
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
+ EC +PG + N C+DI+EC + G+C G
Sbjct: 281 --NQMMEC--LPGYKRVNNTF----------------------CQDINECQ-LQGVCPNG 313
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP------GYCYTALTNGR-CSNQLPQSITK 355
EC NT+ SY C C GF P + C+ P G CY +++GR C + L +TK
Sbjct: 314 ECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTK 373
Query: 356 MQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLC------SVPMVIPGRPEYPPPPLGPI 409
CCC G+ W P E CP+ T F ++C +V V RP + GP+
Sbjct: 374 QLCCCSVGKAWGPHC----EKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPV 429
Query: 410 ----PPVLPVPPGFPPGPQIPVPRPPVEYLYPSRE--------------PPRVLPVNVTD 451
PV P P +P PVE L SRE P + +P +
Sbjct: 430 FVKPKNTQPVAKSTHP-PPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQE 488
Query: 452 YCQLVRYLCQNGRCIPT-------PG--------------SCRCECNKGFQLDLRGECID 490
+L Q I T PG + + Q+ + +
Sbjct: 489 KTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTE 548
Query: 491 VDECEKNP--CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCIN 548
++EC NP C G CIN YTC C GY+ + + +C DIDEC Q +C+ GRC N
Sbjct: 549 INECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCEN 608
Query: 549 TDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKC-ICKPGFQLASD 607
T+GSF C+C AGF + +G NC D+DEC ++C G C+N G+F+C C G+++
Sbjct: 609 TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQR 668
Query: 608 GRYCKDINECETPGICMNGRCVNTDGSYRC----ECFPG-------LAVGLDGRVC---- 652
GR C+DI+EC P C + +CVN+ GSY+C E F G + L+ VC
Sbjct: 669 GR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD 727
Query: 653 ---VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNS-AEYQ 708
++ +C+ GY R + C E G C +N+ ++
Sbjct: 728 CSNLEGSYMCSCHKGYTR----------TPDHKHCRDIDECQQGNLCVNGQCKNTEGSFR 777
Query: 709 ALCSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD 765
C G +++A DI+EC +C +G C N G+++C+C+ GY G +C D
Sbjct: 778 CTCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED 836
Query: 766 INECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCI--NGVCKN 823
INEC+ + +C G C NT GS+ CTCP GF D KTC+DI+ECE G C N
Sbjct: 837 INECLEDKSVCQRGDCINTAGSYDCTCPDGF-QLDDNKTCQDINECEHPGLCGPQGECLN 895
Query: 824 SPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAW 883
+ GSF C C ++ C E I TV D + + + C A
Sbjct: 896 TEGSFHCVCQQGFSISADGRTC-EDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA-- 952
Query: 884 GSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCP----- 938
P G+G C D++ECE+ GVC C N GSF C C
Sbjct: 953 ----------PQDGQG--------CVDVNECELLSGVCGEAFCENVEGSFLCVCADENQE 994
Query: 939 -SGMTLDATGRICLDIRLET---------CFLRYEDEE-CTLPIAGRHRMDACCCSVGAA 987
S MT R D+ ++ C+ D C +A CCC+ GA
Sbjct: 995 YSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAG 1054
Query: 988 WGTEECE--ECPMRNTPEYEELCPRGPGFATKEITN---GKPFFKDINECKMI-PSLCTH 1041
WG + CE CP+ T E+ E+CP+G GF ++ G +KD +EC + +C +
Sbjct: 1055 WG-DNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN 1113
Query: 1042 GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFEC------ 1095
G C NT ++C C G D + C D+DEC+ P C GQCVNT G + C
Sbjct: 1114 GFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPM 1172
Query: 1096 -------KCDEGYESGFMMMKNCMDIDECQR---DPLLCRGGVCHNTEGSYRCECPPGHQ 1145
+C ES + + + D C D +C + C C G
Sbjct: 1173 VLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1232
Query: 1146 LSPNISACIDINECELSAHLC---------PNGR--CVNLIGKYQCACNPGYHSTPDRLF 1194
+ C + + + A LC P GR V+ +Y +P + DR
Sbjct: 1233 WGMQCALC-PLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADP--YFIQDRFL 1289
Query: 1195 C----VDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPN--- 1247
+ +EC I+NG C + Y C C G+ L + +C D++EC++ N
Sbjct: 1290 NSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMS 1349
Query: 1248 ICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN 1282
+C +C N G Y+CLC G++ S+ C +N
Sbjct: 1350 LCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
Score = 480 bits (1236), Expect = e-135
Identities = 293/879 (33%), Positives = 417/879 (47%), Gaps = 113/879 (12%)
Query: 1846 QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECE--RDACGNG 1903
Q + NEC P+IC G CI+ + C+C+ G++ ++ Q C+DI+EC + C G
Sbjct: 545 QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 604
Query: 1904 TCRNTIGSFNCRCNHGFILS-HNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQ-CNEG 1961
C NT GSF C C GF+ S +CIDVDEC ++C G C+NTVG+F+C+ C+ G
Sbjct: 605 RCENTEGSFLCICPAGFMASEEGTNCIDVDECL--RPDVCGEGHCVNTVGAFRCEYCDSG 662
Query: 1962 YEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCI-CPPGYSLQNEKCEDIDECVEE 2020
Y + GR C DI+EC L P C C N GSY+C+ C G+ N +C D+DEC+ E
Sbjct: 663 YRMTQRGR-CEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECL-E 719
Query: 2021 PEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSK 2080
P +CA G CSN EGS+ C C +G++ + + C+D+ C +G C + + +N
Sbjct: 720 PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI--DECQ---QGNLCVNGQCKN--- 771
Query: 2081 QECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHG 2140
+ +FR C G + D D+DEC+ +C HG
Sbjct: 772 ----------------------TEGSFRCTCGQGYQLSAA-KDQCEDIDECQHRHLCAHG 808
Query: 2141 QCINTDGSYRCECPFGYILA--GNECVDTDEC-SVGNPCGNGTCKNVIGGFECTCEEGFE 2197
QC NT+GS++C C GY + G+ C D +EC + C G C N G ++CTC +GF+
Sbjct: 809 QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ 868
Query: 2198 PGPMMTCEDINECAQNPLLCA--FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGK 2255
TC+DINEC ++P LC C+NT GS+ C C G+ + D R C+D DEC
Sbjct: 869 LDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECV--N 925
Query: 2256 HDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYT 2315
+ + C N G++ C+C G+Q DG+GCVD NEC+ G+C C N GS+
Sbjct: 926 NTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFL 985
Query: 2316 CECND-GFTASPNQDECLDNREGYCFTEVLQ-----NMCQIGSSNRN--------PVTKS 2361
C C D SP +C +V Q C ++ + VTK
Sbjct: 986 CVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQ 1045
Query: 2362 ECCCDGGRGWGPHCEI--CPFQGTVAFKKLCPHGRGFMTNG-----------ADIDECKV 2408
ECCC G GWG +CEI CP GT F ++CP G+GF+ G D DEC +
Sbjct: 1046 ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLL 1105
Query: 2409 I-HDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQ 2467
++C+NG C+N R Y C CK G D C D++EC + C NTEGSY
Sbjct: 1106 FGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYN 1165
Query: 2468 CSCPKGYILQEDGRSC-------KDLDECATKQHNC------QFLCVNTIGG-----FTC 2509
C C +L + C + ++E Q C +++C + G C
Sbjct: 1166 CFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTEC 1225
Query: 2510 KCPPGFTQHHTSCIDNNECTSD-INLCGSKGICQNTP----------GSFTCECQRGFSL 2558
C G + + + D LC + P +T E F
Sbjct: 1226 CCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1285
Query: 2559 DQTGSSCEDV--DECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAH 2615
D+ +S E++ +EC + C++G C + GY C C GY CVD NEC +
Sbjct: 1286 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELN 1345
Query: 2616 ----ICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDIN 2650
+C A C NT GSYKC+C G+ C +N
Sbjct: 1346 NRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
Score = 462 bits (1189), Expect = e-129
Identities = 300/894 (33%), Positives = 415/894 (46%), Gaps = 149/894 (16%)
Query: 903 IKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRY 962
I TQ +I+EC V P +C G C+N + C C G R C+DI
Sbjct: 541 IAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI--------- 591
Query: 963 EDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNG 1022
+ECT +H CS G TE C +CP G A++E TN
Sbjct: 592 --DECTQV---QH-----LCSQGRCENTEGSFLC----------ICPAG-FMASEEGTN- 629
Query: 1023 KPFFKDINECKMIPSLCTHGKCRNTIGSFKCR-CDSGFALDSEERNCTDIDECRISPDLC 1081
D++EC + P +C G C NT+G+F+C CDSG+ + R C DIDEC ++P C
Sbjct: 630 ---CIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDEC-LNPSTC 683
Query: 1082 GRGQCVNTPGDFEC-KCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCEC 1140
QCVN+PG ++C C EG+ C+D+DEC +P +C G C N EGSY C C
Sbjct: 684 PDEQCVNSPGSYQCVPCTEGFRG---WNGQCLDVDECL-EPNVCANGDCSNLEGSYMCSC 739
Query: 1141 PPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE 1200
G+ +P+ C DI+EC+ +LC NG+C N G ++C C GY + + C DIDE
Sbjct: 740 HKGYTRTPDHKHCRDIDECQ-QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 798
Query: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE 1260
C + C N+EGS++C C G+ C DI+EC ++ ++C G C N G
Sbjct: 799 CQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGS 858
Query: 1261 YRCLCYDGFMASEDMKTCVDVNECDLNPNIC-LSGTCENTKGSFICHCDMGYSGKKGKTG 1319
Y C C DGF +D KTC D+NEC+ +P +C G C NT+GSF C C G+S
Sbjct: 859 YDCTCPDGFQL-DDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 916
Query: 1320 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG--DGIKCTDLDECSNGTHMCSQH 1377
C DI+EC + C H C NTAGSF+C C G+ DG C D++EC + +C +
Sbjct: 917 CEDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGE- 974
Query: 1378 ADCKNTMGSYRCLCKEG------YTGD--GFTCTDLD-----------ECSENLN---LC 1415
A C+N GS+ C+C + TG T TDLD EC NLN LC
Sbjct: 975 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLC 1034
Query: 1416 GNGQ---------CLNAPGGYRCECDM-------------------GFVPS------ADG 1441
N C + G+ C++ GFVP+ A G
Sbjct: 1035 DNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG 1094
Query: 1442 KACEDIDECSL--PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCIS 1499
+ +D DEC L IC G C N + C C+ G D C D++EC DP++CI
Sbjct: 1095 ENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCID 1154
Query: 1500 GNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN-------CYLDIRPRGDNGDTACSNE 1552
G CVNT GSY C C L+ + C+ N Y D+ + + CS
Sbjct: 1155 GQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRP 1214
Query: 1553 -IGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILC---------PGG--------EG 1594
+G + CCC G+AWG C +CP ++ +Y LC P G E
Sbjct: 1215 LVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQ 1274
Query: 1595 FRPNPITVILED----------IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTR 1644
+ P ++D +EC L G C+ G+C+ + C C GY+L+
Sbjct: 1275 YTPEADPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKM 1333
Query: 1645 VCDDVNECE----TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSL 1694
C DVNEC+ +C C NT G+Y C+C P Y+ + N C + +L
Sbjct: 1334 TCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
Score = 435 bits (1119), Expect = e-121
Identities = 298/931 (32%), Positives = 406/931 (43%), Gaps = 159/931 (17%)
Query: 1593 EGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC 1652
EG+R + DIDEC ++ LC G+C NT GSF C CP G+ +E+ C DV+EC
Sbjct: 577 EGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC 636
Query: 1653 ETPGICGPGTCYNTVGNYTC-ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELL 1711
P +CG G C NTVG + C C Y G C D+ L + TC E
Sbjct: 637 LRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECL-------NPSTCPDEQC 688
Query: 1712 FNMTKKMCCCSYNIG-RAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDEC 1770
N C G R WN C +D+DEC
Sbjct: 689 VNSPGSYQCVPCTEGFRGWNGQC-------------------------------LDVDEC 717
Query: 1771 REIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGS 1830
E P VC NG C N+ GS+ C C G+ C DIDECQ G +C N +C NT GS
Sbjct: 718 LE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCV-NGQCKNTEGS 775
Query: 1831 YRCDCKPGYRFTST-GQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMC 1889
+RC C GY+ ++ QC D +ECQ ++C+HGQC +T GSF C+C G++ + C
Sbjct: 776 FRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC 834
Query: 1890 LDINEC--ERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR-NGQ 1946
DINEC ++ C G C NT GS++C C GF L N C D++EC + LC G+
Sbjct: 835 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE--HPGLCGPQGE 892
Query: 1947 CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL 2006
C+NT GSF C C +G+ ++ DGRTC DI+EC+ + G C N GS+RC+C G+
Sbjct: 893 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA 952
Query: 2007 --QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCP-EGFSLSSSGRRCQ-----DLRM 2058
+ C D++EC +C C N EGSF C+C E S +C+ DL +
Sbjct: 953 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV 1012
Query: 2059 SY---------CYAKF-EGGKCSSPKSRNHSKQECCCALKGEGWGDPCEL--CPTEPDEA 2106
CY + C + + N +KQECCC G GWGD CE+ CP
Sbjct: 1013 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCT-SGAGWGDNCEIFPCPVLGTAE 1071
Query: 2107 FRQICPYGSGII-VGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECV 2165
F ++CP G G + G S + K+ D C +L G E
Sbjct: 1072 FTEMCPKGKGFVPAGESSSEAGGENYKDADEC--------------------LLFGQEI- 1110
Query: 2166 DTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLCAF-RCVN 2223
C NG C N G+EC C++G P+ + C D++EC Q+P C +CVN
Sbjct: 1111 ----------CKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVN 1159
Query: 2224 TYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMEC-KNLIGTYMCICGPGYQR 2282
T GSY C C VL + C E E + Q C ++L Y+C
Sbjct: 1160 TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVC-------S 1212
Query: 2283 RPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTE 2342
RP EC G +C C D ++
Sbjct: 1213 RPLVGKQTTYTECCCLYGEAWGMQCA------LCPLKD--------------------SD 1246
Query: 2343 VLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTV--AFKKLCPHGRGFMTNG 2400
+C I + R + D + P + Q +F++L
Sbjct: 1247 DYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEEL----------- 1295
Query: 2401 ADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC---NQAPKPC-N 2456
+EC +++ C NG CV + Y C C GY D +CVD+NEC N C N
Sbjct: 1296 -QAEECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN 1353
Query: 2457 FICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2487
C NT+GSY+C C GY+ + C L+
Sbjct: 1354 AKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
Score = 432 bits (1112), Expect = e-120
Identities = 281/847 (33%), Positives = 384/847 (45%), Gaps = 101/847 (11%)
Query: 1237 TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTC 1296
T+I+EC NP+IC G C N+P Y C+CY+G+ SE + CVD++EC ++C G C
Sbjct: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
Query: 1297 ENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCS-CSPGW- 1354
ENT+GSF+C C G+ + T C D++EC + CG+ C NT G+F+C C G+
Sbjct: 607 ENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGE-GHCVNTVGAFRCEYCDSGYR 664
Query: 1355 IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL-CKEGYTGDGFTCTDLDECSENLN 1413
+ +C D+DEC N + + C N+ GSY+C+ C EG+ G C D+DEC E N
Sbjct: 665 MTQRGRCEDIDECLNPSTCPDEQ--CVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEP-N 721
Query: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECE 1473
+C NG C N G Y C C G+ + D K C DIDEC N+CV G C N G FRC C
Sbjct: 722 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG 781
Query: 1474 IGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGN 1533
GY+L + C D++EC C G C NT GS+ C C + + C D
Sbjct: 782 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL 841
Query: 1534 CYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILC-PGG 1592
+ RGD C N G C C G + C +N E+ LC P G
Sbjct: 842 EDKSVCQRGD-----CINTAG----SYDCTCPDGFQLDDN-KTCQDINECEHPGLCGPQG 891
Query: 1593 E--------------GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYY 1638
E GF + EDIDEC G C NT GSF+C C G+
Sbjct: 892 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ 951
Query: 1639 LNEDTRVCDDVNECE-TPGICGPGTCYNTVGNYTCICP---PDYMQVNG---GNNCMDM- 1690
+D + C DVNECE G+CG C N G++ C+C +Y + G D+
Sbjct: 952 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD 1011
Query: 1691 --------RRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCE--QCPIPS 1740
+ CY N D CD L N+TK+ CCC+ G W CE CP+
Sbjct: 1012 VDVDQPKEEKKECYYN-LNDASLCDNVLAPNVTKQECCCT--SGAGWGDNCEIFPCPVLG 1068
Query: 1741 TDEFATLCGSQRPGFVIDIYTGLPV------DIDECREI-PGVCENGVCINMVGSFRCEC 1793
T EF +C + GFV + D DEC +C+NG C+N + C C
Sbjct: 1069 TAEFTEMCPKGK-GFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYC 1127
Query: 1794 PVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDC-KPGYRFTSTGQC----- 1847
G +Y+ L C D+DECQ+ C + +C+NT GSY C C P S +C
Sbjct: 1128 KQGTYYDPVKLQCFDMDECQDPSSC-IDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAE 1186
Query: 1848 -NDRNECQEI-----------PNICSHGQCIDTVGSFYCLCHTG-----------FKTND 1884
N++ E ++ +CS C C G K +D
Sbjct: 1187 SNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSD 1246
Query: 1885 DQTMCLDINEC-ERDACGNGTCRNTIGSFNCRCNHGFI---LSHNNDCIDVDECASGNGN 1940
D +I R G + + + FI ++ + + +EC NG
Sbjct: 1247 DYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG- 1305
Query: 1941 LCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINEC-LLEPRK--CAPGTCQNLDGSYR 1997
C NG+C+ + C C +GY + TCVD+NEC L R C C N DGSY+
Sbjct: 1306 -CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK 1364
Query: 1998 CICPPGY 2004
C+C PGY
Sbjct: 1365 CLCLPGY 1371
Score = 389 bits (999), Expect = e-107
Identities = 272/941 (28%), Positives = 382/941 (40%), Gaps = 218/941 (23%)
Query: 1362 TDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLNLCGNGQ 1419
T+++EC+ +C C N Y C+C EGY + C D+DEC++ +LC G+
Sbjct: 547 TEINECTVNPDICGA-GHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR 605
Query: 1420 CLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCE-CEIGYEL 1478
C N G + C C GF+ S +G C D+DEC P++C G C N G FRCE C+ GY +
Sbjct: 606 CENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRM 665
Query: 1479 DRSGGNCTDVNECLDPTTCISGNCVNTPGSYIC-DCPPDFELNPTRVGCVDTRSGNCYLD 1537
+ G C D++ECL+P+TC CVN+PGSY C C F
Sbjct: 666 TQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF-------------------- 704
Query: 1538 IRPRGDNGDTACSNE-IGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFR 1596
RG NG +E + V C +L E +C +G+
Sbjct: 705 ---RGWNGQCLDVDECLEPNVCANGDCSNL-----------------EGSYMCSCHKGYT 744
Query: 1597 PNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG 1656
P DIDECQ+ LC G+C NT GSF+C C GY L+ C+D++EC+
Sbjct: 745 RTPDHKHCRDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH 803
Query: 1657 ICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD-GELLFNMT 1715
+C G C NT G++ C+C Y G++C D+ L D C G+ +
Sbjct: 804 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL------EDKSVCQRGDCINTAG 857
Query: 1716 KKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPG 1775
C C NK C+ DI+EC E PG
Sbjct: 858 SYDCTCPDGFQLDDNKTCQ-------------------------------DINEC-EHPG 885
Query: 1776 VC-ENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCD 1834
+C G C+N GSF C C GF + CEDIDEC N VC + C NTAGS+RC
Sbjct: 886 LCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCL 945
Query: 1835 CKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCH---------TG---FK 1881
C G++ GQ C D NEC+ + +C C + GSF C+C TG +
Sbjct: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSR 1005
Query: 1882 TNDDQTMCLDINECERDAC-----GNGTCRNTIG----SFNCRCNHGFILSHNNDCI--- 1929
T+ D + +D + E+ C C N + C C G N +
Sbjct: 1006 TSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCP 1065
Query: 1930 ---------------------------------DVDECASGNGNLCRNGQCINTVGSFQC 1956
D DEC +C+NG C+NT ++C
Sbjct: 1066 VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYEC 1125
Query: 1957 QCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCIC--PPGYSLQNEKC--- 2011
C +G P C D++EC +P C G C N +GSY C C P ++C
Sbjct: 1126 YCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRP 1184
Query: 2012 EDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCS 2071
+ +E +EE ++ ++ LC E S + CS
Sbjct: 1185 AESNEQIEETDV------------YQDLCWEHLS--------------------DEYVCS 1212
Query: 2072 SPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC---------PYGSGIIVGPD 2122
P + CC L GE WG C LCP + + + Q+C PYG +V
Sbjct: 1213 RPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFS 1272
Query: 2123 D-------------------SAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYIL--AG 2161
+ + +EC + C++G+C+ Y C+C GY L A
Sbjct: 1273 EQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAK 1332
Query: 2162 NECVDTDECSVGNP----CGNGTCKNVIGGFECTCEEGFEP 2198
CVD +EC N C N C N G ++C C G+ P
Sbjct: 1333 MTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVP 1373
Score = 386 bits (992), Expect = e-106
Identities = 279/892 (31%), Positives = 384/892 (43%), Gaps = 162/892 (18%)
Query: 1197 DIDECSIMNGGCET-FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCT 1255
+I+EC++ C C N Y C C G+ QR C DIDEC ++C G+C
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCE 607
Query: 1256 NIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFIC-HCDMGYS-G 1313
N G + C+C GFMASE+ C+DV+EC L P++C G C NT G+F C +CD GY
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMT 666
Query: 1314 KKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-SCSPGWIGDGIKCTDLDECSNGTH 1372
++G+ C DI+EC + C C N+ GS++C C+ G+ G +C D+DEC +
Sbjct: 667 QRGR--CEDIDEC-LNPSTCPDEQ-CVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE-PN 721
Query: 1373 MCSQHADCKNTMGSYRCLCKEGYTG--DGFTCTDLDECSENLNLCGNGQCLNAPGGYRCE 1430
+C+ + DC N GSY C C +GYT D C D+DEC + NLC NGQC N G +RC
Sbjct: 722 VCA-NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCT 779
Query: 1431 CDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNE 1490
C G+ SA CEDIDEC ++C G C N G F+C C+ GY G +C D+NE
Sbjct: 780 CGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 839
Query: 1491 CL-DPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTAC 1549
CL D + C G+C+NT GSY C CP F+L+ + C D P+G+ C
Sbjct: 840 CLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKT-CQDINECEHPGLCGPQGE-----C 893
Query: 1550 SNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDE 1609
N G C C G + C EDIDE
Sbjct: 894 LNTEG----SFHCVCQQGFSISADGRTC---------------------------EDIDE 922
Query: 1610 CQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCYNTVG 1668
C G C NT GSF+C C G+ +D + C DVNECE G+CG C N G
Sbjct: 923 CVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEG 982
Query: 1669 NYTCICPPDYMQVNGGNNCMDMRRSL---------------CYRNYYADNQTCDGELLFN 1713
++ C+C + + + R S CY N D CD L N
Sbjct: 983 SFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLN-DASLCDNVLAPN 1041
Query: 1714 MTKKMCCCSYNIGRAWNKPCE--QCPIPSTDEFATLCG---------------------- 1749
+TK+ CCC+ G W CE CP+ T EF +C
Sbjct: 1042 VTKQECCCTSGAG--WGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKD 1099
Query: 1750 ------------------SQRPGFVIDIYTGL---PV-----DIDECREIPGVCENGVCI 1783
+ RPG+ G PV D+DEC++ P C +G C+
Sbjct: 1100 ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQCV 1158
Query: 1784 NMVGSFR--CECPVGFFYNDKLLVC-----EDIDECQ-----------NGPVCQRNAECI 1825
N GS+ C P+ ++K + E I+E + VC R
Sbjct: 1159 NTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGK 1218
Query: 1826 NTAGSYRCDCKPGYRFTSTGQC-----NDRNECQEIPNICSHGQCIDTVGSFYCLCHTGF 1880
T + C C G + QC D ++ ++ NI G+ +
Sbjct: 1219 QTTYT-ECCCLYGEAWGM--QCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQY 1275
Query: 1881 KTNDDQTMCLD-----INECERDACG------NGTCRNTIGSFNCRCNHGFIL-SHNNDC 1928
D D E + + CG NG C + C C G+ L + C
Sbjct: 1276 TPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTC 1335
Query: 1929 IDVDECASGNG--NLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECL 1978
+DV+EC N +LC+N +CINT GS++C C GY + C +N L
Sbjct: 1336 VDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
Score = 383 bits (983), Expect = e-105
Identities = 282/918 (30%), Positives = 397/918 (43%), Gaps = 167/918 (18%)
Query: 698 PCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVD 757
P P + + E +S + ++INEC ++PDIC G C NL Y CIC GY
Sbjct: 523 PVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFS 582
Query: 758 STGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPC 816
+ CVDI+EC LC G+C NT GSF+C CP GF+ + C D+DEC C
Sbjct: 583 EQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVC 642
Query: 817 INGVCKNSPGSFICE-CSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATL-KSQ 874
G C N+ G+F CE C S + T +G C ID C +N +T Q
Sbjct: 643 GEGHCVNTVGAFRCEYCDSGYRM---------TQRGRCED--ID-EC---LNPSTCPDEQ 687
Query: 875 CCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFK 934
C +S G+ PCT +G+ G QC D+DEC + P VC NG C N GS+
Sbjct: 688 CVNSPGSYQCVPCT---------EGFRGWNG-QCLDVDEC-LEPNVCANGDCSNLEGSYM 736
Query: 935 CQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECE 994
C C G T + C DI DE C G +C
Sbjct: 737 CSCHKGYTRTPDHKHCRDI----------DE----------------CQQGNLCVNGQC- 769
Query: 995 ECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCR 1054
+NT E C G G+ +++ K +DI+EC+ LC HG+CRNT GSF+C
Sbjct: 770 ----KNT-EGSFRCTCGQGY---QLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCV 820
Query: 1055 CDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDI 1114
CD G+ +C DI+EC +C RG C+NT G ++C C +G++ K C DI
Sbjct: 821 CDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ--LDDNKTCQDI 878
Query: 1115 DECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNL 1174
+EC+ L G C NTEGS+ C C G +S + C DI+EC + +G C N
Sbjct: 879 NECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNT 938
Query: 1175 IGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGC-ETFCTNSEGSYECSC---QPGFALM 1230
G ++C C G+ + D CVD++EC +++G C E FC N EGS+ C C ++ M
Sbjct: 939 AGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPM 998
Query: 1231 PDQ---RSCTDIDECEDNP---------NICDGGQCTNIPG----EYRCLCYDG------ 1268
Q R+ TD+D D P N+ D C N+ + C C G
Sbjct: 999 TGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDN 1058
Query: 1269 --------FMASEDMKTC---------------------VDVNECDL-NPNICLSGTCEN 1298
+E + C D +EC L IC +G C N
Sbjct: 1059 CEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLN 1118
Query: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCS------- 1351
T+ + C+C G K C D++EC+ +C C NT GS+ C C+
Sbjct: 1119 TRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSC-IDGQCVNTEGSYNCFCTHPMVLDA 1176
Query: 1352 -------PGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSY----RCLCKEGYTGDGF 1400
P + I+ TD+ + H+ ++ + +G C C G G
Sbjct: 1177 SEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAW-GM 1235
Query: 1401 TCT-----DLDECSENLNLCGNGQCLNAPGGYRCECDMG--FVPSADGKACED------- 1446
C D D+ ++ N+ G+ P G D + P AD +D
Sbjct: 1236 QCALCPLKDSDDYAQLCNIPVTGR--RQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFE 1293
Query: 1447 ---IDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD----PTTCIS 1499
+EC + N C G C + + C+C GY LD + C DVNEC + + C +
Sbjct: 1294 ELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN 1353
Query: 1500 GNCVNTPGSYICDCPPDF 1517
C+NT GSY C C P +
Sbjct: 1354 AKCINTDGSYKCLCLPGY 1371
Score = 315 bits (808), Expect = 3e-85
Identities = 211/621 (33%), Positives = 276/621 (44%), Gaps = 113/621 (18%)
Query: 2126 VDMDECKEPD-VCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCK 2182
VD+DEC + +C G+C NT+GS+ C CP G++ + G C+D DEC + CG G C
Sbjct: 589 VDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCV 648
Query: 2183 NVIGGFECT-CEEGFEPGPMMTCEDINECAQNPLLCAF-RCVNTYGSYEC-KCPVGYVLR 2239
N +G F C C+ G+ CEDI+EC NP C +CVN+ GSY+C C G+ R
Sbjct: 649 NTVGAFRCEYCDSGYRMTQRGRCEDIDECL-NPSTCPDEQCVNSPGSYQCVPCTEGF--R 705
Query: 2240 EDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
C D DEC E + C +C NL G+YMC C GY R PD + C D +ECQ +
Sbjct: 706 GWNGQCLDVDECLE-PNVCANG--DCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-QG 761
Query: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
+C NG+C NT GS+ C C G+ S +D+C D E +++C G RN
Sbjct: 762 NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-----RHLCAHGQC-RNTEG 815
Query: 2360 KSECCCDGG---RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG 2416
+C CD G G G HCE DI+EC VC+ G
Sbjct: 816 SFQCVCDQGYRASGLGDHCE-------------------------DINECLEDKSVCQRG 850
Query: 2417 ECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN--FICKNTEGSYQCSCPKGY 2474
+C+N GSY C C G+ D T C D+NEC P C C NTEGS+ C C +G+
Sbjct: 851 DCINTAGSYDCTCPDGFQLDDNKT-CQDINECEH-PGLCGPQGECLNTEGSFHCVCQQGF 908
Query: 2475 ILQEDGRSCKDLDECATKQH-NCQFLCVNTIGGFTCKCPPGFT--QHHTSCIDNNECTSD 2531
+ DGR+C+D+DEC + C NT G F C C GF Q C+D NEC
Sbjct: 909 SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELL 968
Query: 2532 INLCGSKGICQNTPGSFTCEC---------QRGFSLDQTGSSCE-DVD-------ECEGN 2574
+CG + C+N GSF C C G +T + + DVD EC N
Sbjct: 969 SGVCG-EAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYN 1027
Query: 2575 HRCQHGCQNIIG----------------GYRCS---------------CPQGY------- 2596
C N++ G C CP+G
Sbjct: 1028 LNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGE 1087
Query: 2597 -LQHYQWNQCVDENECL--SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECG 2653
D +ECL IC C NT Y+C C G Y+ C D++EC
Sbjct: 1088 SSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1147
Query: 2654 SAQAPCSYGCSNTEGGYLCGC 2674
+ C NTEG Y C C
Sbjct: 1148 DPSSCIDGQCVNTEGSYNCFC 1168
Score = 309 bits (791), Expect = 3e-83
Identities = 283/988 (28%), Positives = 395/988 (39%), Gaps = 189/988 (19%)
Query: 1816 PVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCL 1875
P + +C T G TS G N +C + P+ + Q ++
Sbjct: 247 PGLSKQEDCCGTVG------------TSWG-FNKCQKCPKKPSYHGYNQMME-------- 285
Query: 1876 CHTGFKTNDDQTMCLDINECE-RDACGNGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDE 1933
C G+K ++ T C DINEC+ + C NG C NT+GS+ C C GF + C+
Sbjct: 286 CLPGYKRVNN-TFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
Query: 1934 CASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLD 1993
S C Y + GR C+ L + C
Sbjct: 345 VISEEKGPC-------------------YRLVSSGRQCMHPLSVHLTKQLCC-------- 377
Query: 1994 GSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG--R 2051
C + EKC GT +FK +CP G + SG R
Sbjct: 378 ----CSVGKAWGPHCEKCP------------LPGT-----AAFKEICPGGMGYTVSGVHR 416
Query: 2052 RCQDLRMSYCYAKFEGGKCSSPKSRN------HSKQECCCAL-----KGEGWGDPCELCP 2100
R F K + P +++ +K+E AL G G +P E+
Sbjct: 417 RRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEP-EVAT 475
Query: 2101 TEPDEAF--------------RQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTD 2146
P++ Q+ P S I + P + +++ P + +T
Sbjct: 476 APPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTS 535
Query: 2147 GSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPMMTCE 2205
+ + P V+ D C G G C N+ + C C EG+ C
Sbjct: 536 SASQVIAPTQVTEINECTVNPDIC------GAGHCINLPVRYTCICYEGYRFSEQQRKCV 589
Query: 2206 DINECAQNPLLCA-FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQME 2264
DI+EC Q LC+ RC NT GS+ C CP G++ E+ C D DEC C E
Sbjct: 590 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEG--H 646
Query: 2265 CKNLIGTYMC-ICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTC-ECNDGF 2322
C N +G + C C GY+ G C D +EC P C + +C+N+ GSY C C +GF
Sbjct: 647 CVNTVGAFRCEYCDSGYRMTQRGR-CEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGF 704
Query: 2323 TASPNQ----DECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEIC 2378
Q DECL+ N+C G + N C C G P + C
Sbjct: 705 RGWNGQCLDVDECLE-----------PNVCANGDCS-NLEGSYMCSCHKGYTRTPDHKHC 752
Query: 2379 PFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDIT 2438
DIDEC+ ++C NG+C N GS+ C C GY
Sbjct: 753 ----------------------RDIDECQQ-GNLCVNGQCKNTEGSFRCTCGQGYQLSAA 789
Query: 2439 GTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ- 2497
C D++EC + C+NTEGS+QC C +GY G C+D++EC + CQ
Sbjct: 790 KDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQR 849
Query: 2498 FLCVNTIGGFTCKCPPGF-TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGF 2556
C+NT G + C CP GF + +C D NEC LCG +G C NT GSF C CQ+GF
Sbjct: 850 GDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHP-GLCGPQGECLNTEGSFHCVCQQGF 908
Query: 2557 SLDQTGSSCEDVDECEGNHRC-QHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LS 2613
S+ G +CED+DEC N C HG C N G +RC C QG+ CVD NEC L
Sbjct: 909 SISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELL 968
Query: 2614 AHICGGASCHNTLGSYKCMC-PAGFQYEQFSGGCQ---------DINECGSAQAPCSYGC 2663
+ +CG A C N GS+ C+C +Y +G C+ D+++ + C Y
Sbjct: 969 SGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYY-- 1026
Query: 2664 SNTEGGYLCG--CPPGYFRIGQGHCVSGMGMGRGNPE---PPVSGEMDDNSLSPEACYEC 2718
N LC P + + C SG G G N E PV G + + P
Sbjct: 1027 -NLNDASLCDNVLAPNVTK-QECCCTSGAGWG-DNCEIFPCPVLGTAEFTEMCP------ 1077
Query: 2719 KINGYPKRGRKRRSTNETDASNIEDQSE 2746
K G+ G S++E N +D E
Sbjct: 1078 KGKGFVPAG---ESSSEAGGENYKDADE 1102
Score = 149 bits (375), Expect = 5e-35
Identities = 143/557 (25%), Positives = 213/557 (38%), Gaps = 151/557 (27%)
Query: 100 CTCPSG-QIAPSCGSRSIQHCNIRCMNG--GSCSDD----HCLCQKGYIGTHCGQPVCES 152
CTCP G Q+ + + I C + G G C + HC+CQ+G+ + G+ CE
Sbjct: 861 CTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR-TCED 919
Query: 153 --GCLNGGRCVAPN---------RCACTYGFTGPQ----------------------CE- 178
C+N C + RC C GF PQ CE
Sbjct: 920 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCEN 979
Query: 179 -------------RDYR--TGPC-----------------------FTVISNQMCQGQLS 200
++Y TG C + + +C L+
Sbjct: 980 VEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLA 1039
Query: 201 GIVCTKTLCCATVGRAWGHPCEMCPA---------QPHPCRRGFIPNIRTGA------CQ 245
V TK CC T G WG CE+ P + P +GF+P + + +
Sbjct: 1040 PNV-TKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYK 1098
Query: 246 DVDECQAI-PGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC 304
D DEC +C+ G C+NT +EC C G + V +C D+DEC P C G+C
Sbjct: 1099 DADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD-PSSCIDGQC 1157
Query: 305 TNTVSSYFCKCPPGFYTSPDGTRCI------------DVRPGYCYTALTNGR-CSNQL-P 350
NT SY C C RCI DV C+ L++ CS L
Sbjct: 1158 VNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVG 1217
Query: 351 QSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIP 410
+ T +CCC G W G+ A +CP++ ++D+ +LC++P + GR +
Sbjct: 1218 KQTTYTECCCLYGEAW--GMQCA--LCPLKDSDDYAQLCNIP--VTGRRQ---------- 1261
Query: 411 PVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQL------VRYLCQNGR 464
P G V E P +P + + + +L + C+NGR
Sbjct: 1262 ---------PYGRDALVDFS--EQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR 1310
Query: 465 CIPTPGSCRCECNKGFQLD-LRGECIDVDECEK-----NPCAGGECINNQGSYTCQCRAG 518
C+ C+C G+ LD + C+DV+EC++ + C +CIN GSY C C G
Sbjct: 1311 CVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPG 1370
Query: 519 YQSTLTRTECRDIDECL 535
Y + C ++ L
Sbjct: 1371 YVPSDKPNYCTPLNTAL 1387
Score = 145 bits (366), Expect = 6e-34
Identities = 140/544 (25%), Positives = 200/544 (36%), Gaps = 150/544 (27%)
Query: 57 NVCGSRYNAYCCPGWKTLPGG----NQCIVPICRHSCGDGFCSRPN---MCTCPSGQIAP 109
N GS C G++ G ++C+ P + C +G CS MC+C G
Sbjct: 690 NSPGSYQCVPCTEGFRGWNGQCLDVDECLEP---NVCANGDCSNLEGSYMCSCHKGY--- 743
Query: 110 SCGSRSIQHCNIR----CMNGGSCSDDHCLCQKGYIGTHCGQ----PVCESGCLNGGRC- 160
+R+ H + R C G C + C +G CGQ + C + C
Sbjct: 744 ---TRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ 800
Query: 161 ----VAPNRCACTYGFTGPQCERDYRTGPCFTVISN-QMCQGQLSGIVCTKTLCCATVGR 215
A +C T G C++ YR + C S VC + C T G
Sbjct: 801 HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKS--VCQRGDCINTAG- 857
Query: 216 AWGHPCEMCPAQPHPCRRGF-IPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKC 273
+ C C GF + + +T CQD++EC+ PGLC G C+NT GSF C C
Sbjct: 858 --SYDCT--------CPDGFQLDDNKT--CQDINECEH-PGLCGPQGECLNTEGSFHCVC 904
Query: 274 PAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVR- 332
G ++ + CEDIDEC G C NT S+ C C GF DG C+DV
Sbjct: 905 QQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNE 964
Query: 333 ----PGYC----------------------YTALTNGRC--------------------- 345
G C Y+ +T G+C
Sbjct: 965 CELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT-GQCRSRTSTDLDVDVDQPKEEKKE 1023
Query: 346 -----------SNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMV 394
N L ++TK +CCC +G W + P CP+ T +F ++C
Sbjct: 1024 CYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFP--CPVLGTAEFTEMC----- 1076
Query: 395 IPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQ 454
P GF P + Y D C
Sbjct: 1077 -------------------PKGKGFVPAGESSSEAGGENY-------------KDADECL 1104
Query: 455 LV-RYLCQNGRCIPTPGSCRCECNKGFQLD-LRGECIDVDEC-EKNPCAGGECINNQGSY 511
L + +C+NG C+ T C C +G D ++ +C D+DEC + + C G+C+N +GSY
Sbjct: 1105 LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSY 1164
Query: 512 TCQC 515
C C
Sbjct: 1165 NCFC 1168
Score = 125 bits (315), Expect = 5e-28
Identities = 66/216 (30%), Positives = 102/216 (47%), Gaps = 19/216 (8%)
Query: 833 SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWG-SPCTLCQ 891
S + + + +T G C+Q I +C + G + + CC ++G +WG + C C
Sbjct: 213 SHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCP 272
Query: 892 VDPI---------CGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMT 942
P C GY R+ T C+DI+EC++ GVC NG C+NT GS++C C G
Sbjct: 273 KKPSYHGYNQMMECLPGYKRVNNTFCQDINECQL-QGVCPNGECLNTMGSYRCTCKIGFG 331
Query: 943 LDATGRIC------LDIRLETCF-LRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEE 995
D T C + C+ L +C P++ CCCSVG AWG CE+
Sbjct: 332 PDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWG-PHCEK 390
Query: 996 CPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
CP+ T ++E+CP G G+ + +P + +
Sbjct: 391 CPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGK 426
Score = 120 bits (300), Expect = 3e-26
Identities = 101/375 (26%), Positives = 138/375 (36%), Gaps = 90/375 (24%)
Query: 56 PNVCGS--------RYNAYCCPGWKTLPGGNQCI-VPIC---RHSCGDGFCSRPN---MC 100
P++CG+ RY C G++ +C+ + C +H C G C +C
Sbjct: 556 PDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLC 615
Query: 101 TCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCL----------CQKGYIGTHCGQPVC 150
CP+G +A G+ I C+ C + HC+ C GY T G+
Sbjct: 616 ICPAGFMASEEGTNCIDVDE--CLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED 673
Query: 151 ESGCLNGGRCVAPNRCA----------CTYGFTG--PQC--------ERDYRTGPCFTVI 190
CLN C +C CT GF G QC G C +
Sbjct: 674 IDECLNPSTC-PDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLE 732
Query: 191 SNQMCQGQLS------------------GIVCTKTLCCATVGRAWGHPCEMCPAQPHPCR 232
+ MC G +C C T G C C
Sbjct: 733 GSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG---SFRCT--------CG 781
Query: 233 RGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDEC 292
+G+ + C+D+DECQ LC G C NT GSF+C C G++ + + CEDI+EC
Sbjct: 782 QGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC 840
Query: 293 STIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV----RPGYCYTALTNGRCSNQ 348
+C+ G+C NT SY C CP GF D C D+ PG C G C N
Sbjct: 841 LEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DNKTCQDINECEHPGLCG---PQGECLN- 895
Query: 349 LPQSITKMQCCCDAG 363
+ C C G
Sbjct: 896 ---TEGSFHCVCQQG 907
Score = 97.4 bits (241), Expect = 2e-19
Identities = 51/131 (38%), Positives = 67/131 (51%), Gaps = 12/131 (9%)
Query: 1471 ECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCV--- 1527
EC GY+ + C D+NEC C +G C+NT GSY C C F +PT CV
Sbjct: 285 ECLPGYKRVNNTF-CQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDP 343
Query: 1528 ---DTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSE 1584
G CY R + C + + V ++K CCCS+GKAWG CE CP T+
Sbjct: 344 PVISEEKGPCY-----RLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAA 398
Query: 1585 YKILCPGGEGF 1595
+K +CPGG G+
Sbjct: 399 FKEICPGGMGY 409
Score = 89.7 bits (221), Expect = 4e-17
Identities = 51/161 (31%), Positives = 75/161 (46%), Gaps = 28/161 (17%)
Query: 1613 LPGLCQGGKCINTFGSF----QC-RCPT-----GY---------YLNEDTRVCDDVNECE 1653
LPGL + C T G+ +C +CP GY Y + C D+NEC+
Sbjct: 246 LPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQ 305
Query: 1654 TPGICGPGTCYNTVGNYTCIC------PPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD 1707
G+C G C NT+G+Y C C P + + + CYR + + C
Sbjct: 306 LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYR-LVSSGRQCM 364
Query: 1708 GELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLC 1748
L ++TK++CCCS +G+AW CE+CP+P T F +C
Sbjct: 365 HPLSVHLTKQLCCCS--VGKAWGPHCEKCPLPGTAAFKEIC 403
Score = 86.7 bits (213), Expect = 3e-16
Identities = 61/196 (31%), Positives = 84/196 (42%), Gaps = 34/196 (17%)
Query: 1933 ECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCA-PGTCQN 1991
+C L + C TVG T N+C P+K + G Q
Sbjct: 241 QCGKALPGLSKQEDCCGTVG-----------------TSWGFNKCQKCPKKPSYHGYNQM 283
Query: 1992 LDGSYRCICPPGYS-LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG 2050
++ C PGY + N C+DI+EC + +C G C NT GS++C C GF +
Sbjct: 284 ME------CLPGYKRVNNTFCQDINEC-QLQGVCPNGECLNTMGSYRCTCKIGFGPDPTF 336
Query: 2051 RRCQ------DLRMSYCYAKFEGGK-CSSPKSRNHSKQECCCALKGEGWGDPCELCPTEP 2103
C CY G+ C P S + +KQ CCC++ G+ WG CE CP
Sbjct: 337 SSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV-GKAWGPHCEKCPLPG 395
Query: 2104 DEAFRQICPYGSGIIV 2119
AF++ICP G G V
Sbjct: 396 TAAFKEICPGGMGYTV 411
Score = 78.2 bits (191), Expect = 1e-13
Identities = 38/116 (32%), Positives = 64/116 (55%), Gaps = 6/116 (5%)
Query: 954 RLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPE-YEELCPRGP 1012
+L CF +C + G + + CC +VG +WG +C++CP + + Y ++ P
Sbjct: 229 QLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
Query: 1013 GFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNC 1068
G+ K + N F +DINEC+ + +C +G+C NT+GS++C C GF D +C
Sbjct: 289 GY--KRVNN--TFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 72.0 bits (175), Expect = 8e-12
Identities = 65/199 (32%), Positives = 85/199 (42%), Gaps = 39/199 (19%)
Query: 2337 GYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPH-CEICP----FQGTVAFKKLCP 2391
G CF E + + C G + + +CC G WG + C+ CP + G + P
Sbjct: 231 GRCFQETIGSQC--GKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLP 288
Query: 2392 -HGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCV-DLNECN 2449
+ R T DI+EC+ + VC NGEC+N GSY C CK G+ PD T +SCV D +
Sbjct: 289 GYKRVNNTFCQDINECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 347
Query: 2450 QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSC-KDLDECATKQHNCQFLCVNTIG--- 2505
+ PC Y L GR C L TKQ LC ++G
Sbjct: 348 EEKGPC------------------YRLVSSGRQCMHPLSVHLTKQ-----LCCCSVGKAW 384
Query: 2506 GFTC-KCP-PGFTQHHTSC 2522
G C KCP PG C
Sbjct: 385 GPHCEKCPLPGTAAFKEIC 403
Score = 66.6 bits (161), Expect = 3e-10
Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 2057 RMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWG-DPCELCPTEPD-EAFRQICPYG 2114
++ C+ + G +C SKQE CC G WG + C+ CP +P + Q+
Sbjct: 229 QLGRCFQETIGSQCGKALP-GLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECL 287
Query: 2115 SGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGY 2157
G + D++EC+ VC +G+C+NT GSYRC C G+
Sbjct: 288 PGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 57.0 bits (136), Expect = 3e-07
Identities = 36/90 (40%), Positives = 46/90 (51%), Gaps = 15/90 (16%)
Query: 147 QPVCESG-CLNGGRCVAPNRCACTYGF----TGPQCERD-----YRTGPCFTVISN-QMC 195
Q VC +G CLN + RC C GF T C D GPC+ ++S+ + C
Sbjct: 307 QGVCPNGECLN---TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQC 363
Query: 196 QGQLSGIVCTKTLCCATVGRAWGHPCEMCP 225
LS + TK LCC +VG+AWG CE CP
Sbjct: 364 MHPLS-VHLTKQLCCCSVGKAWGPHCEKCP 392
Score = 55.5 bits (132), Expect = 8e-07
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Query: 1708 GELLFNMTKKMCCCSYNIGRAWN-KPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVD 1766
G+ L ++K+ CC +G +W C++CP + PG+ + D
Sbjct: 243 GKALPGLSKQEDCCG-TVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK-RVNNTFCQD 300
Query: 1767 IDECREIPGVCENGVCINMVGSFRCECPVGF 1797
I+EC ++ GVC NG C+N +GS+RC C +GF
Sbjct: 301 INEC-QLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 49.3 bits (116), Expect = 5e-05
Identities = 21/34 (61%), Positives = 25/34 (73%), Gaps = 1/34 (2%)
Query: 1806 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGY 1839
C+DI+ECQ VC N EC+NT GSYRC CK G+
Sbjct: 298 CQDINECQLQGVCP-NGECLNTMGSYRCTCKIGF 330
Score = 45.4 bits (106), Expect = 8e-04
Identities = 40/161 (24%), Positives = 57/161 (35%), Gaps = 11/161 (6%)
Query: 2140 GQCINTDGSYRCECPFGYILAGNECVDTDECSVG-NPCGNGTCKNVIGGFE--CTCEEGF 2196
G+C +C + +C T S G N C K G+ C G+
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY 290
Query: 2197 EPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMC-KDEDECEEGK 2255
+ C+DINEC + C+NT GSY C C +G+ C D E K
Sbjct: 291 KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEK 350
Query: 2256 HDC---TEKQMECKNLIGTY----MCICGPGYQRRPDGEGC 2289
C +C + + + +C C G P E C
Sbjct: 351 GPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKC 391
Score = 45.4 bits (106), Expect = 8e-04
Identities = 37/127 (29%), Positives = 49/127 (38%), Gaps = 17/127 (13%)
Query: 2542 QNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQ--------HGCQNIIGGYRCSCP 2593
Q T GS + G S + C V G ++CQ HG ++ C
Sbjct: 235 QETIGSQCGKALPGLSKQE--DCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM-----ECL 287
Query: 2594 QGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYE-QFSGGCQDINEC 2652
GY + C D NEC +C C NT+GSY+C C GF + FS D
Sbjct: 288 PGY-KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 346
Query: 2653 GSAQAPC 2659
+ PC
Sbjct: 347 SEEKGPC 353
Score = 41.2 bits (95), Expect = 0.015
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 1278 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC 1320
C D+NEC L +C +G C NT GS+ C C +G+ + C
Sbjct: 298 CQDINECQLQ-GVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339
Score = 39.3 bits (90), Expect = 0.057
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 19/75 (25%)
Query: 119 CNIRCMNGGSCSDDHCLCQKGYIGTHCGQP---------------VCESGCLNGGRCVAP 163
C + C G SC + C+KG T + +C C+NGG+C +
Sbjct: 35 CKVTCTKG-SCQNS---CEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSR 90
Query: 164 NRCACTYGFTGPQCE 178
++C C FTG C+
Sbjct: 91 DKCQCPPNFTGKLCQ 105
Score = 37.4 bits (85), Expect = 0.22
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 1307 CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW 1354
C GY + T C DINEC++ + C NT GS++C+C G+
Sbjct: 286 CLPGYK-RVNNTFCQDINECQL--QGVCPNGECLNTMGSYRCTCKIGF 330
Score = 35.8 bits (81), Expect = 0.63
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 12/73 (16%)
Query: 2452 PKPCNFICKNTEGSYQCSCPKGY---ILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFT 2508
P C C T+GS Q SC KG ++ E+G + L + C C+N GG
Sbjct: 32 PSICKVTC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMN--GGQC 87
Query: 2509 -----CKCPPGFT 2516
C+CPP FT
Sbjct: 88 SSRDKCQCPPNFT 100
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 481 bits (1239), Expect = e-135
Identities = 483/1787 (27%), Positives = 694/1787 (38%), Gaps = 448/1787 (25%)
Query: 460 CQNG-RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAG-GEC--INNQG--SYTC 513
C NG +C G+ C C F + C D + C PC G C ++ +G Y C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAF---VGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYAC 87
Query: 514 QCRAGYQSTLTRTECRDIDECLQNGRICNNGRCIN--TDGSFHCVCNAGFHVTRDGKNCE 571
C G+ L T + CL N C NG + T + C C G+ GK+C+
Sbjct: 88 SCALGFSGPLCLTPLDNA--CLTNP--CRNGGTCDLLTLTEYKCRCPPGW----SGKSCQ 139
Query: 572 DMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYCK-DINEC-ETPGICMNG-R 627
D C+ N C NG C+ + S+ C C P F G C+ D+NEC + PG+C +G
Sbjct: 140 QADPCA-SNPCANGGQCLPFEASYICHCPPSFH----GPTCRQDVNECGQKPGLCRHGGT 194
Query: 628 CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCAS 687
C N GSYRC VC TH C Y
Sbjct: 195 CHNEVGSYRC-------------VCRATHTGPNCERPYV--------------------- 220
Query: 688 TEYAFGEPCQPCPAQNSAEYQAL------CSSGPGMTSAGSDINECALDPDICPNG-ICE 740
PC P P QN + C+ PG T + N + C NG C
Sbjct: 221 -------PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACV 273
Query: 741 NLRGTYKCICNSGYEVDSTGKNCV-DINECVLNSLLCDNG-QCRNTPGSFVCTCPKGFIY 798
+ TY C C + TG+ C D++EC L C NG C NT G + C C G+
Sbjct: 274 DGVNTYNCRCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTG 329
Query: 799 KPDLKTCEDIDECESSPCINGV-CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTV 857
+ E+ID+C S+ C +G C + SF CEC T +C
Sbjct: 330 ED---CSENIDDCASAACFHGATCHDRVASFYCECPHGRT----GLLC------------ 370
Query: 858 IDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGY----SRIKGTQC-EDID 912
++N A + + C C +P+ GK S G C +D+D
Sbjct: 371 -------HLNDACISNPCNEGSN---------CDTNPVNGKAICTCPSGYTGPACSQDVD 414
Query: 913 ECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPI 971
EC + C++ G C+NT GSF+CQC G T G C +I + C +
Sbjct: 415 ECSLGANPCEHAGKCINTLGSFECQCLQGYT----GPRC-EIDVNEC------------V 457
Query: 972 AGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
+ + DA C + E++ +C PG+ G + +E
Sbjct: 458 SNPCQNDATC----------------LDQIGEFQCICM--PGY------EGVHCEVNTDE 493
Query: 1032 CKMIPSLCTH-GKCRNTIGSFKCRCDSGFALDSEERNCT-DIDECRISPDLCGRG-QCVN 1088
C P C H G+C + I F+C C +GF C D+DEC +P C G +C++
Sbjct: 494 CASSP--CLHNGRCLDKINEFQCECPTGFT----GHLCQYDVDECASTP--CKNGAKCLD 545
Query: 1089 TPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPG---H 1144
P + C C EGY +C +DIDEC DP C G C + ++ C C PG H
Sbjct: 546 GPNTYTCVCTEGYTG-----THCEVDIDECDPDP--CHYGSCKDGVATFTCLCRPGYTGH 598
Query: 1145 QLSPNISACIDINECELSAHLCPNG-RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSI 1203
NI+ C S+ C +G C + Y C C G T +++D+C+
Sbjct: 599 HCETNINEC--------SSQPCRHGGTCQDRDNAYLCFCLKG---TTGPNCEINLDDCA- 646
Query: 1204 MNGGCET-FCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIPGEY 1261
+ C++ C + YEC+C+PG+ +IDEC NP C +GG C + +
Sbjct: 647 -SSPCDSGTCLDKIDGYECACEPGYT---GSMCNINIDECAGNP--CHNGGTCEDGINGF 700
Query: 1262 RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321
C C +G+ D +VNEC+ NP C+ G C ++ + C CD G+SG T C
Sbjct: 701 TCRCPEGY---HDPTCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWSG----TNC- 750
Query: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCK 1381
DIN E ++ C C + + C+C G+ G + T+++EC++ C C
Sbjct: 751 DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ-TNINECASNP--CLNQGTCI 807
Query: 1382 NTMGSYRCLCKEGYTGDGFTC-TDLDECSENLNLCGNG-QCLNAPG--GYRCECDMGFVP 1437
+ + Y+C C YTG TC L C+ + C NG +C + + C C G+
Sbjct: 808 DDVAGYKCNCLLPYTGA--TCEVVLAPCAPSP--CRNGGECRQSEDYESFSCVCPTGW-- 861
Query: 1438 SADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPT 1495
G+ CE DI+EC L +C N G +RC C+ GY SG NC TD+++C
Sbjct: 862 --QGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGY----SGRNCETDIDDCRPNP 915
Query: 1496 TCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGV 1555
G+C + + CDC P F RG T C +I
Sbjct: 916 CHNGGSCTDGINTAFCDCLPGF-----------------------RG----TFCEEDINE 948
Query: 1556 GVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGG-EGFRPNPITVILEDIDECQELP 1614
C S G C C Y CP G G T +C E
Sbjct: 949 -------CASDPCRNGANCTDC----VDSYTCTCPAGFSGIHCENNT------PDCTE-S 990
Query: 1615 GLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCIC 1674
GG C++ SF C CP G+ + DVNEC++ GTC + G+Y C C
Sbjct: 991 SCFNGGTCVDGINSFTCLCPPGF---TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTC 1047
Query: 1675 PPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD--GELLFNMTKKMC-CCSYNIGRAWNK 1731
P Y G NC ++ ++ D+ C G+ T+ C C S G +
Sbjct: 1048 PQGYT----GPNCQNLV-------HWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDV 1096
Query: 1732 PCEQCPIPSTDE---FATLCGSQRPGFVIDI-----------YTGLPVD--IDECREIPG 1775
P C + + + A LC Q G +D YTG + +DEC P
Sbjct: 1097 PSVSCEVAAQRQGVDVARLC--QHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECS--PS 1152
Query: 1776 VCENGV-CINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCD 1834
C+NG C + +G + C+C G+ + E+IDEC + P CQ C++ +Y+C
Sbjct: 1153 PCQNGATCTDYLGGYSCKCVAGYH---GVNCSEEIDECLSHP-CQNGGTCLDLPNTYKCS 1208
Query: 1835 CKPGYRFT----STGQCNDR-NECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMC 1889
C G + + CN + P ++G C+D VG + C C GF +
Sbjct: 1209 CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG-- 1266
Query: 1890 LDINECERDAC---GNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQ 1946
D+NEC + C G C + F+C C G I+ G C+NG
Sbjct: 1267 -DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVIN-----GCKGKPCKNGG 1320
Query: 1947 CI----NTVGSFQCQCNEGYEVAP---DGRTCVDIN-----ECLLEPR------------ 1982
NT F C+C G+E A D RTC + C+ PR
Sbjct: 1321 TCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTG 1380
Query: 1983 -KCA---------------PGTCQNLDGS--YRCICPPGYS------------------- 2005
+C GTC+ S YRC+CP ++
Sbjct: 1381 PECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDI 1440
Query: 2006 ---LQNEKCEDIDECVEEP--EICAL---------------------------------- 2026
L E CE + EC E+ ++C+L
Sbjct: 1441 PPPLIEEACE-LPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKY 1499
Query: 2027 ---GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC 2070
G C + S CL +GF + +C L YC F G C
Sbjct: 1500 FSDGHCDSQCNSAGCLF-DGFDCQRAEGQCNPLYDQYCKDHFSDGHC 1545
Score = 480 bits (1236), Expect = e-135
Identities = 441/1534 (28%), Positives = 620/1534 (40%), Gaps = 326/1534 (21%)
Query: 1284 CDLNPNICLSG-TCENTKGSFICHCDMGYSGKKGKTGCTDINEC-EIGAHNCGK-HAVCT 1340
C CL+G CE G+ C C + G + C D N C N G H V
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPR----CQDPNPCLSTPCKNAGTCHVVDR 79
Query: 1341 NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKN-TMGSYRCLCKEGYTGDG 1399
+ CSC+ G+ G + T LD T+ C C T+ Y+C C G++G
Sbjct: 80 RGVADYACSCALGFSGP-LCLTPLDNACL-TNPCRNGGTCDLLTLTEYKCRCPPGWSGK- 136
Query: 1400 FTCTDLDECSENLNLCGNG-QCLNAPGGYRCECDMGFVPSADGKAC-EDIDECSL-PNIC 1456
+C D C+ N C NG QCL Y C C PS G C +D++EC P +C
Sbjct: 137 -SCQQADPCASNP--CANGGQCLPFEASYICHCP----PSFHGPTCRQDVNECGQKPGLC 189
Query: 1457 VFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPG--SYICDC 1513
G TCHN G +RC C + +G NC P+ C +G G ++ C C
Sbjct: 190 RHGGTCHNEVGSYRCVCRATH----TGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECAC 245
Query: 1514 PPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTP 1573
P F D NC NG AC + GV+ +C
Sbjct: 246 LPGFTGQNCEENIDDCPGNNC--------KNGG-ACVD----GVNTYNC----------- 281
Query: 1574 CEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCR 1632
CP T +Y ED+DECQ +P CQ GG C NT G + C
Sbjct: 282 --RCPPEWTGQY-----------------CTEDVDECQLMPNACQNGGTCHNTHGGYNCV 322
Query: 1633 CPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRR 1692
C G+ ED +++++C + TC++ V ++ C CP +G +
Sbjct: 323 CVNGW-TGEDCS--ENIDDCASAACFHGATCHDRVASFYCECP------HGRTGLLCHLN 373
Query: 1693 SLCYRNYYADNQTCDGELLFNMTKKMCCC-SYNIGRAWNKPCEQCPIPSTD-EFATLCGS 1750
C N + CD + K +C C S G A ++ ++C + + E A C +
Sbjct: 374 DACISNPCNEGSNCDTNPVNG--KAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCIN 431
Query: 1751 QRPGF---VIDIYTG--LPVDIDECREIP-----------------------GV-CE--- 1778
F + YTG +D++EC P GV CE
Sbjct: 432 TLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNT 491
Query: 1779 ----------NGVCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINT 1827
NG C++ + F+CECP GF + +C+ D+DEC + P C+ A+C++
Sbjct: 492 DECASSPCLHNGRCLDKINEFQCECPTGFTGH----LCQYDVDECASTP-CKNGAKCLDG 546
Query: 1828 AGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGF-----KT 1882
+Y C C GY T T D +EC P+ C +G C D V +F CLC G+ +T
Sbjct: 547 PNTYTCVCTEGY--TGTHCEVDIDECD--PDPCHYGSCKDGVATFTCLCRPGYTGHHCET 602
Query: 1883 N------------------DDQTMC------------LDINECERDACGNGTCRNTIGSF 1912
N D+ +C +++++C C +GTC + I +
Sbjct: 603 NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGY 662
Query: 1913 NCRCNHGFILSHNNDCIDVDECASGNGNLCRNG-QCINTVGSFQCQCNEGYEVAPDGRTC 1971
C C G+ S N I++DECA GN C NG C + + F C+C EGY TC
Sbjct: 663 ECACEPGYTGSMCN--INIDECA---GNPCHNGGTCEDGINGFTCRCPEGYH----DPTC 713
Query: 1972 V-DINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICALGTC 2029
+ ++NEC P C G C++ Y+C C PG+S N C+ + +EC P + GTC
Sbjct: 714 LSEVNECNSNP--CVHGACRDSLNGYKCDCDPGWSGTN--CDINNNECESNPCVNG-GTC 768
Query: 2030 SNTEGSFKCLCPEGFSLSSSGRRCQD----------LRMSYCYAKFEGGKCSSPKSRNHS 2079
+ + C C EGFS G CQ L C G KC+ +
Sbjct: 769 KDMTSGYVCTCREGFS----GPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGA 824
Query: 2080 KQECCCALKGEGWGDPC----ELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPD 2135
E A PC E +E E+F +CP G VD++EC
Sbjct: 825 TCEVVLAPCAPS---PCRNGGECRQSEDYESFSCVCPTGWQ----GQTCEVDINECVLSP 877
Query: 2136 VCKHG-QCINTDGSYRCECPFGYILAGNEC-VDTDECSVGNPCGNG-TCKNVIGGFECTC 2192
C+HG C NT G YRC C GY +G C D D+C NPC NG +C + I C C
Sbjct: 878 -CRHGASCQNTHGGYRCHCQAGY--SGRNCETDIDDCRP-NPCHNGGSCTDGINTAFCDC 933
Query: 2193 EEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECE 2252
GF EDINECA +P C + SY C CP G+ CE
Sbjct: 934 LPGFRG--TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGF----------SGIHCE 981
Query: 2253 EGKHDCTEKQM----ECKNLIGTYMCICGPGYQRRPDGEGCV-DENECQTKPGICENGRC 2307
DCTE C + I ++ C+C PG+ G C D NEC ++P + G C
Sbjct: 982 NNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT----GSYCQHDVNECDSQPCL-HGGTC 1036
Query: 2308 LNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDG 2367
+ GSY C C G+T PN N +C + + C+ G T+ C C
Sbjct: 1037 QDGCGSYRCTCPQGYTG-PN----CQNLVHWCDS----SPCKNGGKCWQTHTQYRCECPS 1087
Query: 2368 GRGW--------GPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECV 2419
G W CE+ + V +LC HG G CV
Sbjct: 1088 G--WTGLYCDVPSVSCEVAAQRQGVDVARLCQHG----------------------GLCV 1123
Query: 2420 NDRGSYHCICKTGYTPDITGTSCVDL-NECNQAPKPCNFICKNTEGSYQCSCPKGYILQE 2478
+ ++HC C+ GYT G+ C DL +EC+ +P C + G Y C C GY
Sbjct: 1124 DAGNTHHCRCQAGYT----GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY---- 1175
Query: 2479 DGRSC-KDLDECATKQHNCQF--LCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDIN-- 2533
G +C +++DEC + H CQ C++ + C CP G H I+ ++C ++
Sbjct: 1176 HGVNCSEEIDECLS--HPCQNGGTCLDLPNTYKCSCPRGTQGVHCE-INVDDCNPPVDPV 1232
Query: 2534 ----LCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHGCQNII--- 2585
C + G C + G ++C C GF G CE DV+EC N G QN +
Sbjct: 1233 SRSPKCFNNGTCVDQVGGYSCTCPPGF----VGERCEGDVNECLSNPCDARGTQNCVQRV 1288
Query: 2586 GGYRCSCPQGYLQHYQWNQCVDE-NECLSAHICGGASC---HNTLGSYKCMCPAGFQYEQ 2641
+ C C G+ +C N C G +C NT + C CPAGF+
Sbjct: 1289 NDFHCECRAGHTGR----RCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFE--- 1341
Query: 2642 FSGGCQ-DINECGSAQAPCSYGCSNTEGGYLCGC 2674
C+ D CGS + C + C C
Sbjct: 1342 -GATCENDARTCGSLRCLNGGTCISGPRSPTCLC 1374
Score = 469 bits (1207), Expect = e-131
Identities = 411/1399 (29%), Positives = 586/1399 (41%), Gaps = 250/1399 (17%)
Query: 1367 CSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDEC-SENLNLCGNGQCLNAPG 1425
CS C C+ G+ C+C + G C D + C S G ++ G
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGP--RCQDPNPCLSTPCKNAGTCHVVDRRG 81
Query: 1426 --GYRCECDMGFVPSADGKAC-EDIDECSLPNICVFGTCHNLPGL--FRCECEIGYELDR 1480
Y C C +GF G C +D L N C G +L L ++C C G+
Sbjct: 82 VADYACSCALGF----SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW---- 133
Query: 1481 SGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRP 1540
SG +C + C G C+ SYIC CPP F PT C D+
Sbjct: 134 SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFH-GPT-----------CRQDVNE 181
Query: 1541 RGD------NGDTACSNEIGVGVSKASCCCSLGKAWGT------PCEMCPAVN------T 1582
G +G T C NE+G C C PC P N T
Sbjct: 182 CGQKPGLCRHGGT-CHNEVG----SYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPT 236
Query: 1583 SEYKILCPGGEGFRPNPITVILEDIDECQELPGL-CQ-GGKCINTFGSFQCRCP---TGY 1637
+ C GF E+ID+C PG C+ GG C++ ++ CRCP TG
Sbjct: 237 GDVTHECACLPGFTGQNCE---ENIDDC---PGNNCKNGGACVDGVNTYNCRCPPEWTGQ 290
Query: 1638 YLNEDTRVCDDVNECET-PGIC-GPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLC 1695
Y ED V+EC+ P C GTC+NT G Y C+C + + N D + C
Sbjct: 291 YCTED------VDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAAC 344
Query: 1696 YRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQ---CPI-PSTDEFATLCGSQ 1751
+ ++ + C N N PC + C P + C S
Sbjct: 345 FHGATCHDRVASFYCECPHGRTGLLCHLNDACISN-PCNEGSNCDTNPVNGKAICTCPSG 403
Query: 1752 RPGFVIDIYTG--LPVDIDECREIPGVCEN-GVCINMVGSFRCECPVGFFYNDKLLVCE- 1807
YTG D+DEC CE+ G CIN +GSF C+C G+ CE
Sbjct: 404 --------YTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPR----CEI 451
Query: 1808 DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSH-GQCI 1866
D++EC + P CQ +A C++ G ++C C PGY D EC P C H G+C+
Sbjct: 452 DVNECVSNP-CQNDATCLDQIGEFQCICMPGYEGVHCEVNTD--ECASSP--CLHNGRCL 506
Query: 1867 DTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT-CRNTIGSFNCRCNHGFILSHN 1925
D + F C C TGF + Q D++EC C NG C + ++ C C G+ +H
Sbjct: 507 DKINEFQCECPTGFTGHLCQ---YDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHC 563
Query: 1926 NDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKC 1984
+D+DEC + + C G C + V +F C C GY G C +INEC +P +
Sbjct: 564 E--VDIDEC---DPDPCHYGSCKDGVATFTCLCRPGYT----GHHCETNINECSSQPCRH 614
Query: 1985 APGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICALGTCSNTEGSFKCLCPEG 2043
GTCQ+ D +Y C C G + N CE ++D+C P C GTC + ++C C G
Sbjct: 615 G-GTCQDRDNAYLCFCLKGTTGPN--CEINLDDCASSP--CDSGTCLDKIDGYECACEPG 669
Query: 2044 FSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEP 2103
++ S + + C+ GG C + C C EG+ DP L
Sbjct: 670 YTGSMCNINIDECAGNPCH---NGGTCED----GINGFTCRCP---EGYHDPTCLS---- 715
Query: 2104 DEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNE 2163
+++EC + C HG C ++ Y+C+C G+ +G
Sbjct: 716 -----------------------EVNECNS-NPCVHGACRDSLNGYKCDCDPGW--SGTN 749
Query: 2164 C-VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFR 2220
C ++ +EC NPC NG TCK++ G+ CTC EGF GP C+ +INECA NP L
Sbjct: 750 CDINNNECE-SNPCVNGGTCKDMTSGYVCTCREGFS-GP--NCQTNINECASNPCLNQGT 805
Query: 2221 CVNTYGSYECKCPVGYVLREDRRM--------CKDEDECEEGKHDCTEKQMECKNLIGTY 2272
C++ Y+C C + Y + C++ EC + + ++
Sbjct: 806 CIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSED------------YESF 853
Query: 2273 MCICGPGYQRRPDGEGC-VDENECQTKPGICENGR-CLNTRGSYTCECNDGFTA---SPN 2327
C+C G+Q G+ C VD NEC P C +G C NT G Y C C G++ +
Sbjct: 854 SCVCPTGWQ----GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSGRNCETD 907
Query: 2328 QDECLDN---REGYCFTEVLQNMCQIGSSNRNPVTK---SECCCDGGRGWGPHCEICPFQ 2381
D+C N G C + C R + +EC D R G +C C
Sbjct: 908 IDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRN-GANCTDCVDS 966
Query: 2382 GTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG-ECVNDRGSYHCICKTGYTPDITGT 2440
T CP G + + +C C NG CV+ S+ C+C G+T G+
Sbjct: 967 YTCT----CPAGFSGIHCENNTPDCT--ESSCFNGGTCVDGINSFTCLCPPGFT----GS 1016
Query: 2441 SCV-DLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDE-CATKQHNCQF 2498
C D+NEC+ P C++ GSY+C+CP+GY G +C++L C +
Sbjct: 1017 YCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY----TGPNCQNLVHWCDSSPCKNGG 1072
Query: 2499 LCVNTIGGFTCKCPPGFTQHH-----TSC--IDNNECTSDINLCGSKGICQNTPGSFTCE 2551
C T + C+CP G+T + SC + LC G+C + + C
Sbjct: 1073 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCR 1132
Query: 2552 CQRGFSLDQTGSSCED-VDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608
CQ G+ TGS CED VDEC + CQ+G C + +GGY C C GY + N +
Sbjct: 1133 CQAGY----TGSYCEDLVDECSPS-PCQNGATCTDYLGGYSCKCVAGY---HGVNCSEEI 1184
Query: 2609 NECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ-DINECGSAQAPCSYG----- 2662
+ECLS G +C + +YKC CP G Q C+ ++++C P S
Sbjct: 1185 DECLSHPCQNGGTCLDLPNTYKCSCPRGTQ----GVHCEINVDDCNPPVDPVSRSPKCFN 1240
Query: 2663 ---CSNTEGGYLCGCPPGY 2678
C + GGY C CPPG+
Sbjct: 1241 NGTCVDQVGGYSCTCPPGF 1259
Score = 469 bits (1206), Expect = e-131
Identities = 443/1529 (28%), Positives = 610/1529 (39%), Gaps = 303/1529 (19%)
Query: 1035 IPSLCTHGKCRN-------TIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
+ + C CRN T+ +KCRC G++ ++C D C +P G GQC+
Sbjct: 102 LDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS----GKSCQQADPCASNPCANG-GQCL 156
Query: 1088 NTPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQ 1145
+ C C + C D++EC + P LCR GG CHN GSYRC C H
Sbjct: 157 PFEASYICHCPPSFHG-----PTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHT 211
Query: 1146 LSPNISACIDINECE-----LSAHLCPNGRCVNLIGK--YQCACNPGYHSTPDRLFCVDI 1198
PN CE S C NG G ++CAC PG+ +I
Sbjct: 212 -GPN---------CERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE---ENI 258
Query: 1199 DEC---SIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQC 1254
D+C + NGG C + +Y C C P + Q D+DEC+ PN C +GG C
Sbjct: 259 DDCPGNNCKNGGA---CVDGVNTYNCRCPPEWT---GQYCTEDVDECQLMPNACQNGGTC 312
Query: 1255 TNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFICHCDMGYSG 1313
N G Y C+C +G+ ED +D D C G TC + SF C C G +G
Sbjct: 313 HNTHGGYNCVCVNGW-TGEDCSENID----DCASAACFHGATCHDRVASFYCECPHGRTG 367
Query: 1314 KKGKTGCTDI-NECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTH 1372
I N C G+ NC + V G C+C G+ G D+DECS G +
Sbjct: 368 LLCHLNDACISNPCNEGS-NCDTNPV----NGKAICTCPSGYTGPACS-QDVDECSLGAN 421
Query: 1373 MCSQHADCKNTMGSYRCLCKEGYTG----------------DGFTCTD------------ 1404
C C NT+GS+ C C +GYTG + TC D
Sbjct: 422 PCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPG 481
Query: 1405 ---------LDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE-DIDECSLPN 1454
DEC+ + L NG+CL+ ++CEC GF G C+ D+DEC+
Sbjct: 482 YEGVHCEVNTDECASSPCL-HNGRCLDKINEFQCECPTGFT----GHLCQYDVDECASTP 536
Query: 1455 ICVFGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCISGNCVNTPGSYICDC 1513
C + P + C C GY +G +C D++EC DP C G+C + ++ C C
Sbjct: 537 CKNGAKCLDGPNTYTCVCTEGY----TGTHCEVDIDEC-DPDPCHYGSCKDGVATFTCLC 591
Query: 1514 PPDF-----ELN-------PTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKAS 1561
P + E N P R G N YL +G G +
Sbjct: 592 RPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTG--------------PN 637
Query: 1562 CCCSLGKAWGTPCEMCPAVNTSE-YKILC-PGGEGFRPNPITVILEDIDECQELPGLCQG 1619
C +L +PC+ ++ + Y+ C PG G N +IDEC P G
Sbjct: 638 CEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCN------INIDECAGNP-CHNG 690
Query: 1620 GKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYM 1679
G C + F CRCP GY+ D +VNEC + C G C +++ Y C C P +
Sbjct: 691 GTCEDGINGFTCRCPEGYH---DPTCLSEVNECNS-NPCVHGACRDSLNGYKCDCDPGW- 745
Query: 1680 QVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCC----------CSYNIGRAW 1729
G NC D+ + C N + TC +MT C C NI
Sbjct: 746 ---SGTNC-DINNNECESNPCVNGGTCK-----DMTSGYVCTCREGFSGPNCQTNINECA 796
Query: 1730 NKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINM---V 1786
+ PC D C P YTG ++ P C NG
Sbjct: 797 SNPCLNQGTCIDDVAGYKCNCLLP------YTGATCEVVLAPCAPSPCRNGGECRQSEDY 850
Query: 1787 GSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG 1845
SF C CP G+ + CE DI+EC P C+ A C NT G YRC C+ GY S
Sbjct: 851 ESFSCVCPTGW----QGQTCEVDINECVLSP-CRHGASCQNTHGGYRCHCQAGY---SGR 902
Query: 1846 QC-NDRNECQEIPNICSH-GQCIDTVGSFYCLCHTGFKTNDDQTMC-LDINECERDACGN 1902
C D ++C+ PN C + G C D + + +C C GF+ T C DINEC D C N
Sbjct: 903 NCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECASDPCRN 956
Query: 1903 G-TCRNTIGSFNCRCNHGFILSH-NNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNE 1960
G C + + S+ C C GF H N+ D E + NG G C++ + SF C C
Sbjct: 957 GANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG-----GTCVDGINSFTCLCPP 1011
Query: 1961 GYEVAPDGRTCV-DINECLLEPRKCA-PGTCQNLDGSYRCICPPGYSLQNEKCEDIDECV 2018
G+ G C D+NEC +P C GTCQ+ GSYRC CP GY+ N C+++
Sbjct: 1012 GF----TGSYCQHDVNECDSQP--CLHGGTCQDGCGSYRCTCPQGYTGPN--CQNLVHWC 1063
Query: 2019 EEPEICALGTCSNTEGSFKCLCPEGFS-----LSSSGRRCQDLRMSYCYAKF--EGGKCS 2071
+ G C T ++C CP G++ + S R A+ GG C
Sbjct: 1064 DSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCV 1123
Query: 2072 SPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSG----IIVGPD--DSA 2125
+ +H + C G D + C P + Y G + G + +
Sbjct: 1124 DAGNTHHCR--CQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS 1181
Query: 2126 VDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC-VDTDEC-------SVGNPC- 2176
++DEC G C++ +Y+C CP G G C ++ D+C S C
Sbjct: 1182 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRG--TQGVHCEINVDDCNPPVDPVSRSPKCF 1239
Query: 2177 GNGTCKNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFR----CVNTYGSYECK 2231
NGTC + +GG+ CTC GF CE D+NEC NP C R CV + C+
Sbjct: 1240 NNGTCVDQVGGYSCTCPPGFVG---ERCEGDVNECLSNP--CDARGTQNCVQRVNDFHCE 1294
Query: 2232 CPVGYVLREDRRMCKDEDECEEGKHDCTEKQME-------CKNLIGTYMCICGPGYQRRP 2284
C G+ R CE + C K + N ++C C G+
Sbjct: 1295 CRAGHTGR----------RCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF---- 1340
Query: 2285 DGEGCVDENECQTKPGI-CEN-GRCLNTRGSYTCECNDGFTAS----PNQDECLDNREGY 2338
EG EN+ +T + C N G C++ S TC C FT P CL Y
Sbjct: 1341 --EGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCY 1398
Query: 2339 CFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMT 2398
Q C+ ++ +P + C C F G + G G
Sbjct: 1399 -----NQGTCE--PTSESPFYR--CLCP-----------AKFNGLLCHILDYSFGGG--- 1435
Query: 2399 NGADIDECKVIHDVCRNGECVNDRGSYHC 2427
G DI +I + C EC D G+ C
Sbjct: 1436 AGRDIPP-PLIEEACELPECQEDAGNKVC 1463
Score = 440 bits (1131), Expect = e-122
Identities = 473/1684 (28%), Positives = 643/1684 (38%), Gaps = 446/1684 (26%)
Query: 123 CMNGGSCS----DDHCLCQKGYIGTHCGQP--VCESGCLNGGRC-------VAPNRCACT 169
C+NGG C + C+C ++G C P + C N G C VA C+C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
Query: 170 YGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH 229
GF+GP C T + N C T +
Sbjct: 91 LGFSGPLC---------LTPLDN----------------ACLT----------------N 109
Query: 230 PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDI 289
PCR G G C + T+ ++C+CP G + C+
Sbjct: 110 PCRNG-------GTCD-----------------LLTLTEYKCRCPPGWS----GKSCQQA 141
Query: 290 DECSTIPGICEGGECTNTVSSYFCKCPPGFY---TSPDGTRCIDVRPGYCYTALTNGRCS 346
D C++ P GG+C +SY C CPP F+ D C +PG C G C
Sbjct: 142 DPCASNP-CANGGQCLPFEASYICHCPPSFHGPTCRQDVNEC-GQKPGLCRHG---GTCH 196
Query: 347 NQLPQSITKMQCCCDAGR----CWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYP 402
N+ + +C C A C P V +P C T C
Sbjct: 197 NE----VGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGT------CR------------ 234
Query: 403 PPPLGPIPPVLPVPPGFP-----------PGPQIPVPRPPVEYL--YPSREPPRVLPVNV 449
P G + PGF PG V+ + Y R PP
Sbjct: 235 --PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYC 292
Query: 450 T---DYCQLVRYLCQN-GRCIPTPGSCRCECNKGFQLDLRGECID--------------- 490
T D CQL+ CQN G C T G C C G+ + E ID
Sbjct: 293 TEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHD 352
Query: 491 --------------------VDECEKNPC-AGGECINN--QGSYTCQCRAGYQSTLTRTE 527
D C NPC G C N G C C +GY T
Sbjct: 353 RVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGY----TGPA 408
Query: 528 C-RDIDECLQNGRICNN-GRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLN 584
C +D+DEC C + G+CINT GSF C C G+ G CE D++EC + N C N
Sbjct: 409 CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNEC-VSNPCQN 463
Query: 585 -GMCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNGRCVNTDGSYRCECFPG 642
C+++ G F+CIC PG+ +G +C+ + +EC + NGRC++ ++CEC
Sbjct: 464 DATCLDQIGEFQCICMPGY----EGVHCEVNTDECASSPCLHNGRCLDKINEFQCEC--- 516
Query: 643 LAVGLDGRVC---VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPC 699
G G +C VD CAST G C
Sbjct: 517 -PTGFTGHLCQYDVDE-----------------------------CASTPCKNGAKCLDG 546
Query: 700 PAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDST 759
P Y +C+ G T DI+EC DPD C G C++ T+ C+C GY T
Sbjct: 547 P----NTYTCVCTEGYTGTHCEVDIDEC--DPDPCHYGSCKDGVATFTCLCRPGY----T 596
Query: 760 GKNC-VDINECVLNSLLC-DNGQCRNTPGSFVCTCPKGFIYKPDLKTCE-DIDECESSPC 816
G +C +INEC +S C G C++ +++C C KG CE ++D+C SSPC
Sbjct: 597 GHHCETNINEC--SSQPCRHGGTCQDRDNAYLCFCLKG----TTGPNCEINLDDCASSPC 650
Query: 817 INGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLK---- 872
+G C + + C C T E C G CE ING T +
Sbjct: 651 DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHN---GGTCEDGINGFTCRCPEG 707
Query: 873 ---SQCCSSLGAAWGSPCT-----------LCQVDPICGKGYSRIKGTQCE-DIDECEVF 917
C S + +PC C DP G+S GT C+ + +ECE
Sbjct: 708 YHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDP----GWS---GTNCDINNNECESN 760
Query: 918 PGVCKNGLCVNTRGSFKCQCPSGMT--------LDATGRICLDIRLETCFLRYEDEECT- 968
P V G C + + C C G + + CL+ TC +C
Sbjct: 761 PCV-NGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLN--QGTCIDDVAGYKCNC 817
Query: 969 -LPIAGRHRMDACCCSVGAAWGTEECE---ECPMRNTPEYEE---LCPRGPGFATKEITN 1021
LP G A C V A C EC R + +YE +CP G T E+
Sbjct: 818 LLPYTG-----ATCEVVLAPCAPSPCRNGGEC--RQSEDYESFSCVCPTGWQGQTCEV-- 868
Query: 1022 GKPFFKDINECKMIPSLCTHG-KCRNTIGSFKCRCDSGFALDSEERNC-TDIDECRISPD 1079
DINEC + P C HG C+NT G ++C C +G++ RNC TDID+CR +P
Sbjct: 869 ------DINECVLSP--CRHGASCQNTHGGYRCHCQAGYS----GRNCETDIDDCRPNPC 916
Query: 1080 LCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGV-CHNTEGSYRC 1138
G G C + C C G+ F DI+EC DP CR G C + SY C
Sbjct: 917 HNG-GSCTDGINTAFCDCLPGFRGTFCE----EDINECASDP--CRNGANCTDCVDSYTC 969
Query: 1139 ECPPGHQLSPNISACIDINECELSAHLCPN-GRCVNLIGKYQCACNPGYHSTPDRLFCV- 1196
CP G I + +C S+ C N G CV+ I + C C PG+ + +C
Sbjct: 970 TCPAGFS---GIHCENNTPDCTESS--CFNGGTCVDGINSFTCLCPPGFTGS----YCQH 1020
Query: 1197 DIDECS---IMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQ 1253
D++EC ++GG C + GSY C+C G+ +C ++ D+ +GG+
Sbjct: 1021 DVNECDSQPCLHGGT---CQDGCGSYRCTCPQGYT----GPNCQNLVHWCDSSPCKNGGK 1073
Query: 1254 CTNIPGEYRCLCYDGF------MASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHC 1307
C +YRC C G+ + S + D+ G C + + C C
Sbjct: 1074 CWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRC 1133
Query: 1308 DMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCT-DLDE 1366
GY+G + C D+ + E C A CT+ G + C C G+ G+ C+ ++DE
Sbjct: 1134 QAGYTG----SYCEDLVD-ECSPSPCQNGATCTDYLGGYSCKCVAGY--HGVNCSEEIDE 1186
Query: 1367 CSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTC-TDLDEC-------SENLNLCGNG 1418
C +H C C + +Y+C C G G C ++D+C S + NG
Sbjct: 1187 CL--SHPCQNGGTCLDLPNTYKCSCPRG--TQGVHCEINVDDCNPPVDPVSRSPKCFNNG 1242
Query: 1419 QCLNAPGGYRCECDMGFVPSADGKACE-DIDECSLPNIC-VFGT--CHNLPGLFRCECEI 1474
C++ GGY C C GFV G+ CE D++EC L N C GT C F CEC
Sbjct: 1243 TCVDQVGGYSCTCPPGFV----GERCEGDVNEC-LSNPCDARGTQNCVQRVNDFHCECRA 1297
Query: 1475 GYELDRSGGNCTDV-NECLDPTTCISGNCV---NTPGSYICDCPPDFELNPTRVGCVDTR 1530
G+ +G C V N C G C NT +IC CP FE
Sbjct: 1298 GH----TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFE------------ 1341
Query: 1531 SGNCYLDIRPRGD----NGDTACSNEIGVGVSKASCCCSLGKAWGTPCEM-----C---- 1577
C D R G NG T S G +C C LG G C+ C
Sbjct: 1342 GATCENDARTCGSLRCLNGGTCIS-----GPRSPTCLC-LGPFTGPECQFPASSPCLGGN 1395
Query: 1578 PAVN------TSE---YKILCP---------------GGEGFRPNPITVILE--DIDECQ 1611
P N TSE Y+ LCP GG R P +I E ++ ECQ
Sbjct: 1396 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQ 1455
Query: 1612 ELPG 1615
E G
Sbjct: 1456 EDAG 1459
Score = 247 bits (630), Expect = 1e-64
Identities = 291/1147 (25%), Positives = 437/1147 (38%), Gaps = 203/1147 (17%)
Query: 63 YNAYCCPGWKTLP---GGNQCIVPICRHS--CGDGFCSRPNMCTCPSGQIAPSCGSRSIQ 117
+ C PG++ + ++C C H+ C D C CP+G C +
Sbjct: 474 FQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKI--NEFQCECPTGFTGHLCQYDVDE 531
Query: 118 HCNIRCMNGGSCSDDH----CLCQKGYIGTHCGQPV--CESGCLNGGRC---VAPNRCAC 168
+ C NG C D C+C +GY GTHC + C+ + G C VA C C
Sbjct: 532 CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLC 591
Query: 169 TYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVC------TKTLCCATVGRAWGHPCE 222
G+TG CE + CQ + + +C T C + PC+
Sbjct: 592 RPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD 651
Query: 223 M--CPAQPHPCRRGFIPNIRTGACQ-DVDECQAIPGLCQ-GGNCINTVGSFECKCPAGHK 278
C + P C ++DEC P C GG C + + F C+CP G+
Sbjct: 652 SGTCLDKIDGYECACEPGYTGSMCNINIDECAGNP--CHNGGTCEDGINGFTCRCPEGYH 709
Query: 279 LNEVSQKC-EDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCY 337
C +++EC++ P C G C ++++ Y C C PG+ GT C D+ C
Sbjct: 710 ----DPTCLSEVNECNSNP--CVHGACRDSLNGYKCDCDPGW----SGTNC-DINNNECE 758
Query: 338 T--ALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVI 395
+ + G C + + C C G G + + N+ + V
Sbjct: 759 SNPCVNGGTCKDMTSGYV----CTCREG---FSGPNCQTNINECASNPCLNQGTCIDDVA 811
Query: 396 PGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEY-----LYPSREPPRVLPVNVT 450
+ P G V+ P P R +Y + P+ + V++
Sbjct: 812 GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 871
Query: 451 DYCQLVRYLCQNG-RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPC-AGGECINNQ 508
+ V C++G C T G RC C G+ R D+D+C NPC GG C +
Sbjct: 872 ---ECVLSPCRHGASCQNTHGGYRCHCQAGY--SGRNCETDIDDCRPNPCHNGGSCTDGI 926
Query: 509 GSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHCVCNAGFHVTRDG 567
+ C C G++ T DI+EC + C NG C + S+ C C AGF G
Sbjct: 927 NTAFCDCLPGFRGTFCE---EDINECASDP--CRNGANCTDCVDSYTCTCPAGF----SG 977
Query: 568 KNCEDMDECSIRNMCLN-GMCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMN 625
+CE+ + C N G C++ SF C+C PGF G YC+ D+NEC++
Sbjct: 978 IHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGF----TGSYCQHDVNECDSQPCLHG 1033
Query: 626 GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCC 685
G C + GSYRC C G G + + V S C G G+C + T+ C C
Sbjct: 1034 GTCQDGCGSYRCTCPQGY-TGPNCQNLVHWCDSSPCKNG---GKC----WQTHTQYRCEC 1085
Query: 686 AS--TEYAFGEP---CQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICE 740
S T P C+ + + LC G G+C
Sbjct: 1086 PSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHG----------------------GLCV 1123
Query: 741 NLRGTYKCICNSGYEVDSTGKNCVD-INECVLNSLLCDNG-QCRNTPGSFVCTCPKGFIY 798
+ T+ C C +GY TG C D ++EC + C NG C + G + C C G+
Sbjct: 1124 DAGNTHHCRCQAGY----TGSYCEDLVDEC--SPSPCQNGATCTDYLGGYSCKCVAGY-- 1175
Query: 799 KPDLKTCEDIDECESSPCIN-GVCKNSPGSFICEC--------------SSESTLDPTKT 843
+ E+IDEC S PC N G C + P ++ C C +DP
Sbjct: 1176 -HGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSR 1234
Query: 844 --------ICIETIKG---TCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQV 892
C++ + G TC + RCE ++N +C S+ A G+ + +V
Sbjct: 1235 SPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVN------ECLSNPCDARGTQNCVQRV 1288
Query: 893 DPI---CGKGYSRIKGTQCED-IDECEVFPGVCKNG----LCVNTRGSFKCQCPSGM--- 941
+ C G++ G +CE I+ C+ P CKNG + NT F C+CP+G
Sbjct: 1289 NDFHCECRAGHT---GRRCESVINGCKGKP--CKNGGTCAVASNTARGFICKCPAGFEGA 1343
Query: 942 TLDATGRICLDIRL---ETCFLRYEDEECTL--PIAG---RHRMDACCCSVGAAWGTEEC 993
T + R C +R TC C P G + + C + C
Sbjct: 1344 TCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTC 1403
Query: 994 EECPMRNTPEYEELCP---RGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGS 1050
E P +P Y LCP G + + G +DI +I C +C+ G+
Sbjct: 1404 E--PTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPP-PLIEEACELPECQEDAGN 1460
Query: 1051 FKC--RC----------DSGFALDSEERNCTDIDEC-RISPDLCGRGQCVNTPG----DF 1093
C +C D + +NCT +C + D QC N+ G F
Sbjct: 1461 KVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQC-NSAGCLFDGF 1519
Query: 1094 ECKCDEG 1100
+C+ EG
Sbjct: 1520 DCQRAEG 1526
Score = 198 bits (503), Expect = 7e-50
Identities = 236/918 (25%), Positives = 326/918 (35%), Gaps = 228/918 (24%)
Query: 47 GGGHDALKGPNVCGSRYNAYCCPGWKTLP---GGNQCIVPICRH--SCGDGFCSRPNMCT 101
G D+L G Y C PGW N+C C + +C D + +CT
Sbjct: 728 GACRDSLNG-------YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKD--MTSGYVCT 778
Query: 102 CPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD----HCLCQKGYIGTHCG---QPVCESGC 154
C G P+C + + + C+N G+C DD C C Y G C P S C
Sbjct: 779 CREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPC 838
Query: 155 LNGGRCVAPN-----RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLC 209
NGG C C C G+ G CE D CQ G C C
Sbjct: 839 RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH---C 895
Query: 210 CATVGRAWGHPCE--MCPAQPHPCRRG-------------FIPNIRTGAC-QDVDECQAI 253
A G CE + +P+PC G +P R C +D++EC +
Sbjct: 896 QAGYS---GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 952
Query: 254 PGLCQ-GGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYF 312
P C+ G NC + V S+ C CPAG D E S GG C + ++S+
Sbjct: 953 P--CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCF----NGGTCVDGINSFT 1006
Query: 313 CKCPPGF---YTSPDGTRCIDVRP----GYCYTALTNGRCSNQLPQSITKMQC------- 358
C CPPGF Y D C D +P G C + RC+ PQ T C
Sbjct: 1007 CLCPPGFTGSYCQHDVNEC-DSQPCLHGGTCQDGCGSYRCT--CPQGYTGPNCQNLVHWC 1063
Query: 359 ----CCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLP 414
C + G+CW E CP T C VP V
Sbjct: 1064 DSSPCKNGGKCWQTHTQYRCE-CPSGWT---GLYCDVPSV-------------------- 1099
Query: 415 VPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQN-GRCIPTPGSCR 473
++ R V+ V LCQ+ G C+ +
Sbjct: 1100 -------SCEVAAQRQGVD----------------------VARLCQHGGLCVDAGNTHH 1130
Query: 474 CECNKGFQLDLRGECID-VDECEKNPCA-GGECINNQGSYTCQCRAGYQSTLTRTECRDI 531
C C G+ C D VDEC +PC G C + G Y+C+C AGY E I
Sbjct: 1131 CRCQAGY---TGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEE---I 1184
Query: 532 DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDEC-------SIRNMCL 583
DECL + N G C++ ++ C C G G +CE ++D+C S C
Sbjct: 1185 DECLSH-PCQNGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPVDPVSRSPKCF 1239
Query: 584 -NGMCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNG--RCVNTDGSYRCEC 639
NG C+++ G + C C PGF G C+ D+NEC + G CV + CEC
Sbjct: 1240 NNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC 1295
Query: 640 FPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPC 699
G GR C + G K C C ++ A G C+ C
Sbjct: 1296 ----RAGHTGRRC------ESVINGCKGKPC--------KNGGTCAVASNTARGFICK-C 1336
Query: 700 PAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDST 759
PA A C + + +N G C + + C+C + T
Sbjct: 1337 PAGFEG---ATCENDARTCGSLRCLN----------GGTCISGPRSPTCLCLGPF----T 1379
Query: 760 GKNC--VDINECVLNSLLCDNGQCRNTPGS--FVCTCPKGF------------------- 796
G C + C+ + + G C T S + C CP F
Sbjct: 1380 GPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRD 1439
Query: 797 IYKPDLKTCEDIDECESSPCINGVCKNSPGSFIC-----ECSSESTLDPTKTICIETIKG 851
I P ++ ++ EC+ N VC + C +CS DP K C ++++
Sbjct: 1440 IPPPLIEEACELPECQED-AGNKVCSLQCNNHACGWDGGDCSLNFN-DPWKN-CTQSLQ- 1495
Query: 852 TCWQTVIDGRCEININGA 869
CW+ DG C+ N A
Sbjct: 1496 -CWKYFSDGHCDSQCNSA 1512
Score = 112 bits (280), Expect = 5e-24
Identities = 100/346 (28%), Positives = 147/346 (42%), Gaps = 62/346 (17%)
Query: 59 CGSRYNAYCCPGWKTLPGGN--QCIVPICRHSCGDGFCSRP-----NMCTCPSGQIAPSC 111
C + +Y C T G N + VP C +G RP + C C G +C
Sbjct: 195 CHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNC 254
Query: 112 GSRSIQHC-NIRCMNGGSCSDD----HCLCQKGYIGTHCGQPVCE-----SGCLNGGRCV 161
+I C C NGG+C D +C C + G +C + V E + C NGG C
Sbjct: 255 -EENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCH 313
Query: 162 APN---RCACTYGFTGPQCERD---------YRTGPCFTVISNQMCQGQ--LSGIVCTKT 207
+ C C G+TG C + + C +++ C+ +G++C
Sbjct: 314 NTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN 373
Query: 208 LCCATVGRAWGHPCEMCPAQPHP---CRRGFIPNIRTG-AC-QDVDECQAIPGLCQ-GGN 261
C + G C+ P C G+ TG AC QDVDEC C+ G
Sbjct: 374 DACISNPCNEGSNCDTNPVNGKAICTCPSGY-----TGPACSQDVDECSLGANPCEHAGK 428
Query: 262 CINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEG-GECTNTVSSYFCKCPPGF 319
CINT+GSFEC+C G+ +CE D++EC + P C+ C + + + C C PG+
Sbjct: 429 CINTLGSFECQCLQGY----TGPRCEIDVNECVSNP--CQNDATCLDQIGEFQCICMPGY 482
Query: 320 YTSPDGTRCIDVRPGYCYTA--LTNGRCSNQLPQSITKMQCCCDAG 363
+G C +V C ++ L NGRC ++ I + QC C G
Sbjct: 483 ----EGVHC-EVNTDECASSPCLHNGRCLDK----INEFQCECPTG 519
Score = 92.8 bits (229), Expect = 4e-18
Identities = 94/370 (25%), Positives = 140/370 (37%), Gaps = 92/370 (24%)
Query: 66 YC-CPGWKT---LPGGNQCIVPICRH--SCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 119
YC CP +T + CI C +C + +CTCPSG P+C S+ + C
Sbjct: 358 YCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC-SQDVDEC 416
Query: 120 NIR---CMNGGSCSDD----HCLCQKGYIGTHCGQPVCE---SGCLNGGRC---VAPNRC 166
++ C + G C + C C +GY G C V E + C N C + +C
Sbjct: 417 SLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQC 476
Query: 167 ACTYGFTGPQCE---RDYRTGPCFTVISNQMCQGQLSGIVC------TKTLCCATVGRAW 217
C G+ G CE + + PC + N C +++ C T LC V
Sbjct: 477 ICMPGYEGVHCEVNTDECASSPC---LHNGRCLDKINEFQCECPTGFTGHLCQYDVDECA 533
Query: 218 GHPCE---MCPAQPHP----CRRGFIPNIRTGA-CQ-DVDECQAIPGLCQGGNCINTVGS 268
PC+ C P+ C G+ TG C+ D+DEC P C G+C + V +
Sbjct: 534 STPCKNGAKCLDGPNTYTCVCTEGY-----TGTHCEVDIDECDPDP--CHYGSCKDGVAT 586
Query: 269 FECKCPAGH-------KLNEVSQK-------CED---------------------IDECS 293
F C C G+ +NE S + C+D +D+C+
Sbjct: 587 FTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCA 646
Query: 294 TIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSI 353
+ P C+ G C + + Y C C PG+ S + C+ G C + I
Sbjct: 647 SSP--CDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCH---NGGTCED----GI 697
Query: 354 TKMQCCCDAG 363
C C G
Sbjct: 698 NGFTCRCPEG 707
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 443 bits (1140), Expect = e-123
Identities = 418/1472 (28%), Positives = 578/1472 (39%), Gaps = 279/1472 (18%)
Query: 1333 CGKHAVCTNTAG-SFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTM----GSY 1387
C CT C C PGW+G+ +C D C +G C+ C++++ +
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGE--RCQLEDPCHSGP--CAGRGVCQSSVVAGTARF 104
Query: 1388 RCLCKEGYTGDGFTCTDLDECSENLNLCGNG-QCLNAPGG-YRCECDMGFVPSADGKACE 1445
C C G+ G C+ D C + C +G +C P G + C C G+ G++C
Sbjct: 105 SCRCPRGFRGPD--CSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGY----QGRSCR 156
Query: 1446 -DIDECSLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCV 1503
D+DEC + C G TC N PG FRC+C GY +G C + P+ C +G
Sbjct: 157 SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLCENPAVPCAPSPCRNGGTC 212
Query: 1504 NTPG--SYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKAS 1561
G +Y C C P FE V D C NG T GV+ +
Sbjct: 213 RQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCL--------NGGTCVD-----GVNTYN 259
Query: 1562 CCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ-GG 1620
C CP T ++ ED+DECQ P C GG
Sbjct: 260 C-------------QCPPEWTGQF-----------------CTEDVDECQLQPNACHNGG 289
Query: 1621 KCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQ 1680
C NT G C C G+ ++ DD C T TC++ V ++ C CP
Sbjct: 290 TCFNTLGGHSCVCVNGWTGESCSQNIDD---CATAVCFHGATCHDRVASFYCACPM---- 342
Query: 1681 VNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNI-GRAWNKPCEQCPIP 1739
G + C N ++ CD + + +C C G A ++ ++C I
Sbjct: 343 --GKTGLLCHLDDACVSNPCHEDAICDTNPVNG--RAICTCPPGFTGGACDQDVDECSIG 398
Query: 1740 STD-EFATLCGSQRPGFVIDI---YTG--------------------------------- 1762
+ E C + + F+ YTG
Sbjct: 399 ANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICM 458
Query: 1763 -------LPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNG 1815
VDIDEC+ P V GVC + V F C CP GF + L D+DEC +
Sbjct: 459 AGFTGTYCEVDIDECQSSPCV-NGGVCKDRVNGFSCTCPSGFSGSTCQL---DVDECAST 514
Query: 1816 PVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCL 1875
P C+ A+C++ Y C C G+ G DRN P+ C HG+C+D + SF C
Sbjct: 515 P-CRNGAKCVDQPDGYECRCAEGFE----GTLCDRNVDDCSPDPCHHGRCVDGIASFSCA 569
Query: 1876 CHTGFKTNDDQTMCLDINECERDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCIDVDEC 1934
C G+ ++ ++EC C +G C + + + CRC G + N +++D+C
Sbjct: 570 CAPGYTGTRCESQ---VDECRSQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDC 624
Query: 1935 ASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNL 1992
AS N C G C + + + C C G+ G C V+INEC P C G +C +
Sbjct: 625 AS---NPCTFGVCRDGINRYDCVCQPGFT----GPLCNVEINECASSP--CGEGGSCVDG 675
Query: 1993 DGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRR 2052
+ +RC+CPPG SL C EP C+ G C + G F+C+C G+S G R
Sbjct: 676 ENGFRCLCPPG-SLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWS----GPR 728
Query: 2053 C-QDLRMSYCYAK--FEGGKCSSPKSRNHSK-----QECCCALKGEGWGDPCE---LCPT 2101
C Q L C ++ GG CSS H Q C L +PCE C +
Sbjct: 729 CSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCES 788
Query: 2102 EPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVC-KHGQCINTDGSYRCECPFGYILA 2160
P + CP G GP D+DEC P C HG C N GS+ C C GY
Sbjct: 789 APGQLPVCSCPQGWQ---GPRCQQ-DVDECAGPAPCGPHGICTNLAGSFSCTCHGGY--T 842
Query: 2161 GNEC-VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCA 2218
G C D ++C NPC NG +C++ +G F C+C GF GP D++EC NP C
Sbjct: 843 GPSCDQDINDCDP-NPCLNGGSCQDGVGSFSCSCLPGFA-GPRCA-RDVDECLSNP--CG 897
Query: 2219 -FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQM----ECKNLIGTYM 2273
C + S+ C CP GY CE+ DC+ C + + ++
Sbjct: 898 PGTCTDHVASFTCTCPPGY----------GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFS 947
Query: 2274 CICGPGYQRRPDGEGCVDENE-CQTKPGICENGRCLNTRGSYTCECNDGFTASPNQ---D 2329
C+C PGY G C E + C ++P + G C + C C + FT Q D
Sbjct: 948 CLCRPGYT----GAHCQHEADPCLSRPCL-HGGVCSAAHPGFRCTCLESFTGPQCQTLVD 1002
Query: 2330 ECLDN---REGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCE-ICPFQGTVA 2385
C G C +C G S R +S C + G E +C G
Sbjct: 1003 WCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCV 1062
Query: 2386 FKK-----LCPHGRGFMTNGADIDECKVIHDVCRNG-ECVNDRGSYHCICKTGYTPDITG 2439
+ +CP GR ++D C + C++G C G Y C C GY G
Sbjct: 1063 DEDSSHYCVCPEGRTGSHCEQEVDPC--LAQPCQHGGTCRGYMGGYMCECLPGYN----G 1116
Query: 2440 TSCVD-LNECNQAPKPCNFICKNTEGSYQCSCPKGY------ILQEDGRSCKDLDECATK 2492
+C D ++EC P C + Y CSCP G I ++D LD
Sbjct: 1117 DNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRC 1176
Query: 2493 QHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGIC---------QN 2543
HN CV+ +GGF C CPPG+T C +DIN C S G C Q+
Sbjct: 1177 LHNGT--CVDLVGGFRCTCPPGYT--------GLRCEADINECRS-GACHAAHTRDCLQD 1225
Query: 2544 TPGSFTCECQRGFSLDQTGSSCEDV-DECEGNHRCQHG--CQNIIG-----GYRCSCPQG 2595
G F C C GFS G C+ V CE + CQHG C+ G + C C Q
Sbjct: 1226 PGGGFRCLCHAGFS----GPRCQTVLSPCE-SQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1280
Query: 2596 YLQHYQWNQCVDE--NECLSAHICGGASCHNTLGSYKCMCPAGF---QYEQFSGGCQDIN 2650
+ W + C G C T +C CP G F G +
Sbjct: 1281 F-----WGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGAS 1335
Query: 2651 ECGSAQAPCSYGCSNTEGG----YLCGCPPGY 2678
A APC +G S + C C G+
Sbjct: 1336 NASCAAAPCLHGGSCRPAPLAPFFRCACAQGW 1367
Score = 412 bits (1060), Expect = e-114
Identities = 439/1687 (26%), Positives = 641/1687 (37%), Gaps = 325/1687 (19%)
Query: 623 CMNG-RCVNTDG-SYRCECFPGLAVGLDGRVCVDTHMRSTCYGG--YKRGQCIKPLFGAV 678
C NG RC C C PG G C + C+ G RG C +
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWV----GERC---QLEDPCHSGPCAGRGVCQSSVVAGT 101
Query: 679 TKSECCCA----STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDIC 734
+ C C + + +PC P + A C++ PD
Sbjct: 102 ARFSCRCPRGFRGPDCSLPDPCLSSPCAHGAR--------------------CSVGPD-- 139
Query: 735 PNGICENLRGTYKCICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCP 793
G + C C GY+ G++C D++EC + G C NTPGSF C CP
Sbjct: 140 ---------GRFLCSCPPGYQ----GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCP 186
Query: 794 KGFIYKPDLKTCED-IDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGT 852
G+ CE+ C SPC NG G +C+ C+ +G
Sbjct: 187 AGYTG----PLCENPAVPCAPSPCRNGGTCRQSGDLTYDCA-----------CLPGFEGQ 231
Query: 853 CWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQC-EDI 911
CE+N++ +C + G CQ P G C ED+
Sbjct: 232 --------NCEVNVDDCP-GHRCLNGGTCVDGVNTYNCQCPP-------EWTGQFCTEDV 275
Query: 912 DECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCF--LRYEDEECT 968
DEC++ P C N G C NT G C C +G T ++ + D CF D +
Sbjct: 276 DECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS 335
Query: 969 LPIAGRHRMDACCCSVGAAWGTEECEECPM--RNTPEYEELCPRGPGFATKEITNGKPFF 1026
A C + A + C E + N +C PGF G
Sbjct: 336 FYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF------TGGACD 389
Query: 1027 KDINECKMIPSLCTH-GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ 1085
+D++EC + + C H G+C NT GSF C+C G+ + R TD++EC +S +
Sbjct: 390 QDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY---TGPRCETDVNEC-LSGPCRNQAT 445
Query: 1086 CVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQ 1145
C++ G F C C G+ + +DIDECQ P + GGVC + + C CP G
Sbjct: 446 CLDRIGQFTCICMAGFTGTYCE----VDIDECQSSPCV-NGGVCKDRVNGFSCTCPSGFS 500
Query: 1146 LSPNISACIDINECELSAHLCPNG-RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIM 1204
S + +D++EC ++ C NG +CV+ Y+C C G+ T L ++D+CS
Sbjct: 501 GS---TCQLDVDEC--ASTPCRNGAKCVDQPDGYECRCAEGFEGT---LCDRNVDDCS-P 551
Query: 1205 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264
+ C + S+ C+C PG+ R + +DEC P GG+C ++ +Y C
Sbjct: 552 DPCHHGRCVDGIASFSCACAPGYT---GTRCESQVDECRSQP-CRHGGKCLDLVDKYLCR 607
Query: 1265 CYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDIN 1324
C G + + V++++C NP C G C + + C C G++G +IN
Sbjct: 608 CPSG---TTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGFTGPLCN---VEIN 659
Query: 1325 ECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCS----QHADC 1380
EC + CG+ C + F+C C PG + C +H C+ H C
Sbjct: 660 EC--ASSPCGEGGSCVDGENGFRCLCPPGSLP--------PLCLPPSHPCAHEPCSHGIC 709
Query: 1381 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD 1440
+ G +RC+C+ G++G + + + E+ G C + G+ C C P
Sbjct: 710 YDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCP----PGVQ 765
Query: 1441 GKACEDIDECSLPNICVF-GTCHNLPG-LFRCECEIGYELDRSGGNC-TDVNECLDPTTC 1497
G+ CE + C+ PN C G C + PG L C C G++ G C DV+EC P C
Sbjct: 766 GRQCELLSPCT-PNPCEHGGRCESAPGQLPVCSCPQGWQ----GPRCQQDVDECAGPAPC 820
Query: 1498 -ISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
G C N GS+ C C + T C D +C D P + G +C + G
Sbjct: 821 GPHGICTNLAGSFSCTCHGGY----TGPSC-DQDINDC--DPNPCLNGG--SCQD----G 867
Query: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL 1616
V SC C PG G R D+DEC P
Sbjct: 868 VGSFSCSC------------------------LPGFAGPR------CARDVDECLSNP-- 895
Query: 1617 CQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPP 1676
C G C + SF C CP GY D+ +C GTC + V +++C+C P
Sbjct: 896 CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRP 952
Query: 1677 DYMQV---NGGNNCMD---MRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWN 1730
Y + + C+ + +C + TC L + T C +
Sbjct: 953 GYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTC----LESFTGPQ--CQTLVDWCSR 1006
Query: 1731 KPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECRE--------IPGVCE-NGV 1781
+PC+ LC G + DI LP CRE + +C+ G
Sbjct: 1007 QPCQNGGRCVQTGAYCLCPPGWSGRLCDI-RSLP-----CREAAAQIGVRLEQLCQAGGQ 1060
Query: 1782 CINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGYR 1840
C++ S C CP G + CE ++D C P CQ C G Y C+C PGY
Sbjct: 1061 CVDEDSSHYCVCPEGRTGSH----CEQEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYN 1115
Query: 1841 FTSTGQCNDRNECQEIPNICSH-GQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDA 1899
+ +D +EC P C H G CID V + C C G + +INE D
Sbjct: 1116 GDNCE--DDVDECASQP--CQHGGSCIDLVARYLCSCPPG-----TLGVLCEINE---DD 1163
Query: 1900 CG-------------NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQ 1946
CG NGTC + +G F C C G+ D++EC SG +
Sbjct: 1164 CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE--ADINECRSGACHAAHTRD 1221
Query: 1947 CI-NTVGSFQCQCNEGYEVAPDGRTCVDI-NECLLEP----RKCAPGTCQNLDGSYRCIC 2000
C+ + G F+C C+ G+ G C + + C +P +C P ++ C C
Sbjct: 1222 CLQDPGGGFRCLCHAGF----SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHC 1277
Query: 2001 PPGYSLQNEKCEDIDECVEEPEICALGT-CSNTEGSFKCLCPEGFSLSSSGRRCQDLRMS 2059
+ +CE + E + C +G C T +C CP G SG C+ S
Sbjct: 1278 AQPF--WGPRCERVARSCRELQ-CPVGVPCQQTPRGPRCACPPGL----SGPSCRSFPGS 1330
Query: 2060 -------YCYAK--FEGGKCSSPKSRNHSKQECCCALKGEGWGDP-CELCPTEPDEAFRQ 2109
C A GG C + C CA +GW P CE P+ +
Sbjct: 1331 PPGASNASCAAAPCLHGGSCRPAPLAPFFR--CACA---QGWTGPRCEAPAAAPEVSEEP 1385
Query: 2110 ICPYGSGIIVGPDDSAVDMDECKEPDV-----------------CKHGQCINTDGSYRCE 2152
CP + D D EC P C+ QC + RC+
Sbjct: 1386 RCP-RAACQAKRGDQRCDR-ECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCD 1443
Query: 2153 CPFGYILAGNECV-DTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECA 2211
+ C+ D +C G TC V +E C + F G + EC
Sbjct: 1444 ----PACSSPACLYDNFDCHAGG--RERTCNPV---YEKYCADHFADGRCDQGCNTEECG 1494
Query: 2212 QNPLLCA 2218
+ L CA
Sbjct: 1495 WDGLDCA 1501
Score = 399 bits (1025), Expect = e-110
Identities = 432/1600 (27%), Positives = 618/1600 (38%), Gaps = 379/1600 (23%)
Query: 769 CVLNSLLCDNGQCRNTPG-SFVCTCPKGFIYKPDLKTCEDIDECESSPCIN-GVCKNSPG 826
C+ S + G+C P C CP G++ + C+ D C S PC GVC++S
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGE----RCQLEDPCHSGPCAGRGVCQSS-- 96
Query: 827 SFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSP 886
+ T + +C RC G CS SP
Sbjct: 97 -----------------VVAGTARFSC-------RCPRGFRGPD-----CSLPDPCLSSP 127
Query: 887 CT---LCQVDP------ICGKGYSRIKGTQCE-DIDECEVFPGVCKNGLCVNTRGSFKCQ 936
C C V P C GY +G C D+DEC V G C+NT GSF+CQ
Sbjct: 128 CAHGARCSVGPDGRFLCSCPPGY---QGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQ 184
Query: 937 CPSGMT-----------------LDATGRICLDIRLE-TCFLRYEDEECTLPI---AGRH 975
CP+G T T R D+ + C +E + C + + G
Sbjct: 185 CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR 244
Query: 976 RMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMI 1035
++ C G T C +CP PE+ G+ +D++EC++
Sbjct: 245 CLNGGTCVDGV--NTYNC-QCP----PEW----------------TGQFCTEDVDECQLQ 281
Query: 1036 PSLCTH-GKCRNTIGSFKCRCDSGFALDSEERNCTDIDEC-------------RISPDLC 1081
P+ C + G C NT+G C C +G+ +S +N ID+C R++ C
Sbjct: 282 PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQN---IDDCATAVCFHGATCHDRVASFYC 338
Query: 1082 G------------RGQCVNTP-------------GDFECKCDEGYESGFMMMKNCMDIDE 1116
CV+ P G C C G+ G D+DE
Sbjct: 339 ACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGAC----DQDVDE 394
Query: 1117 CQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLI 1175
C C G C NT+GS+ C+C G+ P D+NEC LS C++ I
Sbjct: 395 CSIGANPCEHLGRCVNTQGSFLCQCGRGY-TGPRCET--DVNEC-LSGPCRNQATCLDRI 450
Query: 1176 GKYQCACNPGYHSTPDRLFC-VDIDECS---IMNGGCETFCTNSEGSYECSCQPGFALMP 1231
G++ C C G+ T +C VDIDEC +NGG C + + C+C GF+
Sbjct: 451 GQFTCICMAGFTGT----YCEVDIDECQSSPCVNGG---VCKDRVNGFSCTCPSGFSGST 503
Query: 1232 DQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNIC 1291
Q D+DEC P +G +C + P Y C C +GF T D N D +P+ C
Sbjct: 504 CQ---LDVDECASTP-CRNGAKCVDQPDGYECRCAEGFEG-----TLCDRNVDDCSPDPC 554
Query: 1292 LSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCS 1351
G C + SF C C GY+G + + + ++EC + C C + + C C
Sbjct: 555 HHGRCVDGIASFSCACAPGYTGTRCE---SQVDECR--SQPCRHGGKCLDLVDKYLCRCP 609
Query: 1352 PGWIGDGIKC-TDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSE 1410
G G+ C ++D+C+ ++ C+ C++ + Y C+C+ G+TG +++EC+
Sbjct: 610 SG--TTGVNCEVNIDDCA--SNPCT-FGVCRDGINRYDCVCQPGFTGP-LCNVEINECAS 663
Query: 1411 NLNLCG-NGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFR 1469
+ CG G C++ G+RC C G +P C C G C++ PG FR
Sbjct: 664 --SPCGEGGSCVDGENGFRCLCPPGSLP----PLCLPPSHPCAHEPCSHGICYDAPGGFR 717
Query: 1470 CECEIGYELDRSGGNCTD--VNECLDPTTCISGNCVNTPG-SYICDCPPDFE------LN 1520
C CE G+ SG C+ + + C +G ++ G + C CPP + L+
Sbjct: 718 CVCEPGW----SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLS 773
Query: 1521 P------TRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPC 1574
P G ++ G + P+G G C ++ A C P
Sbjct: 774 PCTPNPCEHGGRCESAPGQLPVCSCPQGWQG-PRCQQDVDECAGPAPC---------GPH 823
Query: 1575 EMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCP 1634
+C + + C GG P +DI++C P L GG C + GSF C C
Sbjct: 824 GICTNL-AGSFSCTCHGG---YTGPSCD--QDINDCDPNPCL-NGGSCQDGVGSFSCSCL 876
Query: 1635 TGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSL 1694
G+ R DV+EC CGPGTC + V ++TC CPP Y GG +C
Sbjct: 877 PGF---AGPRCARDVDEC-LSNPCGPGTCTDHVASFTCTCPPGY----GGFHCEQ----- 923
Query: 1695 CYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPG 1754
D C FN C + + F+ LC RPG
Sbjct: 924 -------DLPDCSPSSCFN----------------GGTC----VDGVNSFSCLC---RPG 953
Query: 1755 FVIDIYTGLPV--DIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCED-IDE 1811
YTG + D C P GVC FRC C F C+ +D
Sbjct: 954 -----YTGAHCQHEADPCLSRP-CLHGGVCSAAHPGFRCTCLESFTGPQ----CQTLVDW 1003
Query: 1812 CQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRN-ECQE--------IPNIC-S 1861
C P CQ C+ T G+Y C C PG+ S C+ R+ C+E + +C +
Sbjct: 1004 CSRQP-CQNGGRCVQT-GAY-CLCPPGW---SGRLCDIRSLPCREAAAQIGVRLEQLCQA 1057
Query: 1862 HGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGN-GTCRNTIGSFNCRCNHGF 1920
GQC+D S YC+C G + + +++ C C + GTCR +G + C C G+
Sbjct: 1058 GGQCVDEDSSHYCVCPEGRTGSHCEQ---EVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1114
Query: 1921 ILSHNNDCIDVDECASGNGNLCRN-GQCINTVGSFQCQCNEG-----YEVAPDGRTCVDI 1974
+ D DVDECAS C++ G CI+ V + C C G E+ D C
Sbjct: 1115 NGDNCED--DVDECAS---QPCQHGGSCIDLVARYLCSCPPGTLGVLCEINED--DCGPG 1167
Query: 1975 NECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICALGTC---- 2029
PR GTC +L G +RC CPPGY+ +CE DI+E C G C
Sbjct: 1168 PPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT--GLRCEADINE-------CRSGACHAAH 1218
Query: 2030 -----SNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK--FEGGKC-SSPKSRNHSKQ 2081
+ G F+CLC GF SG RCQ + +S C ++ GG+C SP
Sbjct: 1219 TRDCLQDPGGGFRCLCHAGF----SGPRCQTV-LSPCESQPCQHGGQCRPSPGPGGGLTF 1273
Query: 2082 ECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQ 2141
C CA WG CE E CP G
Sbjct: 1274 TCHCA--QPFWGPRCERVARSCREL---QCPVGV-------------------------P 1303
Query: 2142 CINTDGSYRCECPFGYILAGNEC---------VDTDECSVGNPCGNGTCK--NVIGGFEC 2190
C T RC CP G L+G C C+ G+C+ + F C
Sbjct: 1304 CQQTPRGPRCACPPG--LSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRC 1361
Query: 2191 TCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 2230
C +G+ E ++ P C G C
Sbjct: 1362 ACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRC 1401
Score = 396 bits (1018), Expect = e-109
Identities = 409/1427 (28%), Positives = 572/1427 (40%), Gaps = 269/1427 (18%)
Query: 396 PGRPEYPPPPLGPIPPVLPVP-PGFPPGPQI---PVPRPPVEYLYPSREPPRVLPVN-VT 450
P P PPPP+ +P +L + PG P + P PSRE + P V
Sbjct: 14 PMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVG 73
Query: 451 DYCQLVRYLCQNGRCIPTPGSCR-----------CECNKGFQLDLRG-ECIDVDECEKNP 498
+ CQL C +G C G C+ C C +GF RG +C D C +P
Sbjct: 74 ERCQL-EDPCHSGPCAGR-GVCQSSVVAGTARFSCRCPRGF----RGPDCSLPDPCLSSP 127
Query: 499 CA-GGEC-INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCV 556
CA G C + G + C C GYQ R+ D+DEC + G C+NT GSF C
Sbjct: 128 CAHGARCSVGPDGRFLCSCPPGYQGRSCRS---DVDECRVGEPCRHGGTCLNTPGSFRCQ 184
Query: 557 CNAGF---------------------------HVTRD--------GKNCE-DMDECSIRN 580
C AG+ +T D G+NCE ++D+C +
Sbjct: 185 CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP-GH 243
Query: 581 MCLN-GMCINEDGSFKCICKPGFQLASDGRYC-KDINECE-TPGICMN-GRCVNTDGSYR 636
CLN G C++ ++ C C P + G++C +D++EC+ P C N G C NT G +
Sbjct: 244 RCLNGGTCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHS 299
Query: 637 CECFPGLAVGLDGRVC---VDTHMRSTCYGGYKRGQCIKPLFGA--VTKSECCCASTEYA 691
C C G G C +D + C+ G + + A + K+ C +
Sbjct: 300 CVCVNGWT----GESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDAC 355
Query: 692 FGEPCQP---CPAQNSAEYQALCSSGPGMT--SAGSDINECALDPDICPN-GICENLRGT 745
PC C N +A+C+ PG T + D++EC++ + C + G C N +G+
Sbjct: 356 VSNPCHEDAICDT-NPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGS 414
Query: 746 YKCICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKT 804
+ C C GY TG C D+NEC L+ + C + G F C C GF
Sbjct: 415 FLCQCGRGY----TGPRCETDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFTG----TY 465
Query: 805 CE-DIDECESSPCIN-GVCKNSPGSFICEC-----SSESTLDPTKTICIETIKGTCWQTV 857
CE DIDEC+SSPC+N GVCK+ F C C S LD + G
Sbjct: 466 CEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQ 525
Query: 858 IDG---RCEININGATLKSQCCSSLGAAWGSPC-------TLCQVDPICGKGYSRIKGTQ 907
DG RC G + C ++ PC + C GY+ GT+
Sbjct: 526 PDGYECRCAEGFEG----TLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYT---GTR 578
Query: 908 CE-DIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDE 965
CE +DEC P C++ G C++ + C+CPSG TG C ++ ++ C
Sbjct: 579 CESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSG----TTGVNC-EVNIDDC----ASN 627
Query: 966 ECTLPIA--GRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGK 1023
CT + G +R D C C G P+ N E C P +G+
Sbjct: 628 PCTFGVCRDGINRYD-CVCQPGFTG--------PLCNVEINE--CASSPCGEGGSCVDGE 676
Query: 1024 PFFKDINECKMIPSL------------CTHGKCRNTIGSFKCRCDSGFALDSEERNCTDI 1071
F+ + +P L C+HG C + G F+C C+ G++ ++
Sbjct: 677 NGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLAR- 735
Query: 1072 DECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHN 1131
D C P G G C + F C C G + + C + C +P GG C +
Sbjct: 736 DACESQPCRAG-GTCSSDGMGFHCTCPPGVQG-----RQCELLSPCTPNPCE-HGGRCES 788
Query: 1132 TEGSYR-CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTP 1190
G C CP G Q P D++EC A P+G C NL G + C C+ GY
Sbjct: 789 APGQLPVCSCPQGWQ-GPRCQQ--DVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPS 845
Query: 1191 DRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD 1250
D D +NGG C + GS+ CSC PGFA R D+DEC NP C
Sbjct: 846 CDQDINDCDPNPCLNGGS---CQDGVGSFSCSCLPGFA---GPRCARDVDECLSNP--CG 897
Query: 1251 GGQCTNIPGEYRCLC---YDGFMASEDMKTCVDVNECDLNPNICLS-GTCENTKGSFICH 1306
G CT+ + C C Y GF +D+ C +P+ C + GTC + SF C
Sbjct: 898 PGTCTDHVASFTCTCPPGYGGFHCEQDLPDC--------SPSSCFNGGTCVDGVNSFSCL 949
Query: 1307 CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDE 1366
C GY+G + + + C + C VC+ F+C+C + G + T +D
Sbjct: 950 CRPGYTGAHCQ---HEADPCL--SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQ-TLVDW 1003
Query: 1367 CSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENL--------NLC-GN 1417
CS C C T G+Y CLC G++G L C E LC
Sbjct: 1004 CSR--QPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSL-PCREAAAQIGVRLEQLCQAG 1058
Query: 1418 GQCLNAPGGYRCECDMGFVPSADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGY 1476
GQC++ + C C G G CE ++D C GTC G + CEC GY
Sbjct: 1059 GQCVDEDSSHYCVCPEG----RTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1114
Query: 1477 ELDRSGGNC-TDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCY 1535
+G NC DV+EC G+C++ Y+C CPP T + +C
Sbjct: 1115 ----NGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPG-----TLGVLCEINEDDC- 1164
Query: 1536 LDIRPRGDNGDTACSNEIGVG-VSKASCCCSLGKAWGTPCE---------MCPAVNTSEY 1585
P D+G N V V C C G G CE C A +T +
Sbjct: 1165 -GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT-GLRCEADINECRSGACHAAHTRDC 1222
Query: 1586 KILCPGGEGFR---------PNPITVILEDIDECQELPGLCQ-GGKCINTFG-----SFQ 1630
+ PGG GFR P TV + C+ P CQ GG+C + G +F
Sbjct: 1223 -LQDPGG-GFRCLCHAGFSGPRCQTV----LSPCESQP--CQHGGQCRPSPGPGGGLTFT 1274
Query: 1631 CRCPTGYYLNEDTRVCDDVNECETP-GICGPGTCYNTVGNYTCICPP 1676
C C ++ RV E + P G+ C T C CPP
Sbjct: 1275 CHCAQPFWGPRCERVARSCRELQCPVGV----PCQQTPRGPRCACPP 1317
Score = 375 bits (964), Expect = e-103
Identities = 426/1598 (26%), Positives = 586/1598 (36%), Gaps = 354/1598 (22%)
Query: 95 SRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD--------HCLCQKGYIGTHCG 146
SR C CP G + C H C G C C C +G+ G C
Sbjct: 60 SREAACLCPPGWVGERCQLEDPCHSG-PCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS 118
Query: 147 --QPVCESGCLNGGRC-VAPN---RCACTYGFTGPQCERDY---RTG-PCFTVISNQMCQ 196
P S C +G RC V P+ C+C G+ G C D R G PC
Sbjct: 119 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPC---------- 168
Query: 197 GQLSGIVCTKT---LCCATVGRAWGHPCE--MCPAQPHPCRRG--------------FIP 237
G C T C G CE P P PCR G +P
Sbjct: 169 --RHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLP 226
Query: 238 NIRTGACQ-DVDECQAIPG--LCQGGNCINTVGSFECKCPAGHKLNEVSQKC-EDIDECS 293
C+ +VD+C PG GG C++ V ++ C+CP Q C ED+DEC
Sbjct: 227 GFEGQNCEVNVDDC---PGHRCLNGGTCVDGVNTYNCQCPP----EWTGQFCTEDVDECQ 279
Query: 294 TIPGIC-EGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQS 352
P C GG C NT+ + C C G+ D C+ T C ++
Sbjct: 280 LQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGAT---CHDR---- 332
Query: 353 ITKMQCCCDAGR----CWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGP 408
+ C C G+ C V+ C A D N + GR
Sbjct: 333 VASFYCACPMGKTGLLCHLDDACVS-NPCHEDAICDTNP-------VNGR---------- 374
Query: 409 IPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQN-GRCIP 467
+ PPGF G D C + C++ GRC+
Sbjct: 375 --AICTCPPGFTGG----------------------ACDQDVDECSIGANPCEHLGRCVN 410
Query: 468 TPGSCRCECNKGFQLDLRGECIDVDECEKNPCAG-GECINNQGSYTCQCRAGYQSTLTRT 526
T GS C+C +G+ R E DV+EC PC C++ G +TC C AG+ T
Sbjct: 411 TQGSFLCQCGRGY-TGPRCE-TDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV 468
Query: 527 ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLNG 585
DIDEC Q+ N G C + F C C +GF G C+ D+DEC+ C NG
Sbjct: 469 ---DIDEC-QSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVDECA-STPCRNG 519
Query: 586 -MCINEDGSFKCICKPGFQLASDGRYC-KDINECETPGICMNGRCVNTDGSYRCECFPGL 643
C+++ ++C C GF +G C +++++C +P C +GRCV+ S+ C C PG
Sbjct: 520 AKCVDQPDGYECRCAEGF----EGTLCDRNVDDC-SPDPCHHGRCVDGIASFSCACAPGY 574
Query: 644 AVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQN 703
G VD C G G+C+ +
Sbjct: 575 -TGTRCESQVDECRSQPCRHG---GKCLDLV----------------------------- 601
Query: 704 SAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 763
+Y C SG + +I++CA +P C G+C + Y C+C G+ TG C
Sbjct: 602 -DKYLCRCPSGTTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGF----TGPLC 654
Query: 764 -VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCK 822
V+INEC +S + G C + F C CP G + P L C PC +G+C
Sbjct: 655 NVEINECA-SSPCGEGGSCVDGENGFRCLCPPGSL--PPL-CLPPSHPCAHEPCSHGICY 710
Query: 823 NSPGSFIC---------ECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKS 873
++PG F C CS D ++ GTC + C ++
Sbjct: 711 DAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRA-GGTCSSDGMGFHCTC---PPGVQG 766
Query: 874 QCCSSLGAAWGSPCT---LCQVDP------ICGKGYSRIKGTQC-EDIDECEVFPGVC-K 922
+ C L +PC C+ P C +G+ +G +C +D+DEC P C
Sbjct: 767 RQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGW---QGPRCQQDVDEC-AGPAPCGP 822
Query: 923 NGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCC 982
+G+C N GSF C C G TG C D + C + C ++ C
Sbjct: 823 HGICTNLAGSFSCTCHGGY----TGPSC-DQDINDC----DPNPC---------LNGGSC 864
Query: 983 SVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHG 1042
G + C PGFA G +D++EC P C G
Sbjct: 865 QDGVGSFSCSCL-----------------PGFA------GPRCARDVDECLSNP--CGPG 899
Query: 1043 KCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC-GRGQCVNTPGDFECKCDEGY 1101
C + + SF C C G+ E+ D+ +C SP C G CV+ F C C GY
Sbjct: 900 TCTDHVASFTCTCPPGYGGFHCEQ---DLPDC--SPSSCFNGGTCVDGVNSFSCLCRPGY 954
Query: 1102 ESGFMMMKNCM-DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECE 1160
+C + D C P L GGVC +RC C P +D
Sbjct: 955 TGA-----HCQHEADPCLSRPCL-HGGVCSAAHPGFRCTCLESF-TGPQCQTLVD----W 1003
Query: 1161 LSAHLCPN-GRCVNLIGKYQCACNPGY-------HSTPDRLFCVDID---ECSIMNGGCE 1209
S C N GRCV G Y C C PG+ S P R I E GG
Sbjct: 1004 CSRQPCQNGGRCVQ-TGAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG-- 1059
Query: 1210 TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD-GGQCTNIPGEYRCLCYDG 1268
C + + S+ C C G ++D C P C GG C G Y C C G
Sbjct: 1060 -QCVDEDSSHYCVCPEG---RTGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPG 1113
Query: 1269 FMAS--EDMKTCVDVNECDLNPNICL-SGTCENTKGSFICHCDMGYSGKKGKTGCTDINE 1325
+ ED DV+EC P C G+C + ++C C G G +INE
Sbjct: 1114 YNGDNCED-----DVDECASQP--CQHGGSCIDLVARYLCSCPPGTLGV-----LCEINE 1161
Query: 1326 CEIG-------AHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKC-TDLDECSNGTHMCSQH 1377
+ G C + C + G F+C+C PG+ G++C D++EC +G +
Sbjct: 1162 DDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY--TGLRCEADINECRSGACHAAHT 1219
Query: 1378 ADC-KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPG-----GYRCEC 1431
DC ++ G +RCLC G++G C + E+ GQC +PG + C C
Sbjct: 1220 RDCLQDPGGGFRCLCHAGFSGP--RCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHC 1277
Query: 1432 DMGFVPSADGKACEDIDECSLPNICVFGT-CHNLPGLFRCECEIGYELDRSGGNCTDVNE 1490
F G CE + C G C P RC C G SG +C
Sbjct: 1278 AQPFW----GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGL----SGPSCRSFPG 1329
Query: 1491 CLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSG-NC-------YLDIRPR- 1541
P + +C P + C P R C +G C + PR
Sbjct: 1330 --SPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRC 1387
Query: 1542 ------GDNGDTACSNEI---GVGVSKASCCCSLGKAW 1570
GD C E G G C S+G W
Sbjct: 1388 PRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPW 1425
Score = 280 bits (716), Expect = 1e-74
Identities = 289/1074 (26%), Positives = 409/1074 (38%), Gaps = 227/1074 (21%)
Query: 460 CQNG-RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAG 518
C+NG +C+ P C C +GF+ L +VD+C +PC G C++ S++C C G
Sbjct: 516 CRNGAKCVDQPDGYECRCAEGFEGTLCDR--NVDDCSPDPCHHGRCVDGIASFSCACAPG 573
Query: 519 YQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHCVCNAGFHVTRDGKNCE-DMDEC 576
Y T ++ +DEC + C +G +C++ + C C +G G NCE ++D+C
Sbjct: 574 YTGTRCESQ---VDEC--RSQPCRHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDC 624
Query: 577 SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNGRCVNTDGSY 635
+ N C G+C + + C+C+PGF G C +INEC + G CV+ + +
Sbjct: 625 A-SNPCTFGVCRDGINRYDCVCQPGFT----GPLCNVEINECASSPCGEGGSCVDGENGF 679
Query: 636 RCECFPGLAVGL-------------DGRVCVDTH--MRSTCYGGYKRGQCIKPLFGAVTK 680
RC C PG L +C D R C G+ +C + L +
Sbjct: 680 RCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACE 739
Query: 681 SECC-----CASTEYAF---------GEPCQ---PCPAQNSAEYQALCSSGPGMTSAGS- 722
S+ C C+S F G C+ PC N E+ C S PG S
Sbjct: 740 SQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC-TPNPCEHGGRCESAPGQLPVCSC 798
Query: 723 -----------DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC-VDINECV 770
D++ECA P+GIC NL G++ C C+ GY TG +C DIN+C
Sbjct: 799 PQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDCD 854
Query: 771 LNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFIC 830
N L + G C++ GSF C+C GF + D+DEC S+PC G C + SF C
Sbjct: 855 PNPCL-NGGSCQDGVGSFSCSCLPGF---AGPRCARDVDECLSNPCGPGTCTDHVASFTC 910
Query: 831 EC--------SSESTLDPTKTICIETIKGTCWQTV--IDGRCEININGATLKSQC--CSS 878
C + D + + C GTC V C GA + + C S
Sbjct: 911 TCPPGYGGFHCEQDLPDCSPSSCFN--GGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLS 968
Query: 879 LGAAWGSPCTLCQVDPICGKGYSRIKGTQCED-IDECEVFPGVCKN-GLCVNTRGSFKCQ 936
G C+ C G QC+ +D C P C+N G CV T G++ C
Sbjct: 969 RPCLHGGVCSAAHPGFRC-TCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT-GAY-CL 1023
Query: 937 CPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEEC 996
CP G +GR+C DIR C E I R++ C + G + C
Sbjct: 1024 CPPGW----SGRLC-DIRSLPC------REAAAQIG--VRLEQLCQAGGQCVDEDSSHYC 1070
Query: 997 PMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTH-GKCRNTIGSFKCRC 1055
+CP G G ++++ C P C H G CR +G + C C
Sbjct: 1071 ----------VCPEG--------RTGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCEC 1110
Query: 1056 DSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDID 1115
G+ D+ E D+DEC P G G C++ + C C G G + N D
Sbjct: 1111 LPGYNGDNCE---DDVDECASQPCQHG-GSCIDLVARYLCSCPPG-TLGVLCEIN---ED 1162
Query: 1116 ECQRDPLLCRG------GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNG 1169
+C P L G G C + G +RC CPPG+ + DINEC A +
Sbjct: 1163 DCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY---TGLRCEADINECRSGACHAAHT 1219
Query: 1170 RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1229
R C +PG G + C C GF+
Sbjct: 1220 R--------DCLQDPG-------------------------------GGFRCLCHAGFS- 1239
Query: 1230 MPDQRSCTDIDECEDNPNICD-GGQCTNIPG-----EYRCLCYDGFMASEDMKTCVDVNE 1283
R T + CE P C GGQC PG + C C F + E
Sbjct: 1240 --GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRE 1295
Query: 1284 CDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTA 1343
+ C+ T C C G SG C GA N A
Sbjct: 1296 LQCPVGV----PCQQTPRGPRCACPPGLSG----PSCRSFPGSPPGASNASCAAAPCLHG 1347
Query: 1344 GS---------FKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEG 1394
GS F+C+C+ GW G + + C + A C+ G RC +
Sbjct: 1348 GSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPR-AACQAKRGDQRCDRECN 1406
Query: 1395 YTGDGFTCTDLDECSENL----NLCGNGQCLNAPGGYRCECDMGFVPSADGKAC 1444
G G+ D +CS ++ C QC RC+ P+ AC
Sbjct: 1407 SPGCGW---DGGDCSLSVGDPWRQCEALQCWRLFNNSRCD------PACSSPAC 1451
Score = 246 bits (627), Expect = 3e-64
Identities = 329/1305 (25%), Positives = 461/1305 (35%), Gaps = 276/1305 (21%)
Query: 66 YC-CPGWKT---LPGGNQCIVPICRHS--CGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 119
YC CP KT + C+ C C + +CTCP G +C + + C
Sbjct: 337 YCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGAC-DQDVDEC 395
Query: 120 NIR---CMNGGSCSDDH----CLCQKGYIGTHCGQPV--CESG-CLNGGRC---VAPNRC 166
+I C + G C + C C +GY G C V C SG C N C + C
Sbjct: 396 SIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455
Query: 167 ACTYGFTGPQCERDY---RTGPCFTVISNQMCQGQLSGIVCT------KTLCCATVGRAW 217
C GFTG CE D ++ PC ++ +C+ +++G CT + C V
Sbjct: 456 ICMAGFTGTYCEVDIDECQSSPC---VNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECA 512
Query: 218 GHPCE---MCPAQPH----PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFE 270
PC C QP C GF + ++VD+C P C G C++ + SF
Sbjct: 513 STPCRNGAKCVDQPDGYECRCAEGFEGTL---CDRNVDDCS--PDPCHHGRCVDGIASFS 567
Query: 271 CKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI 329
C C G+ +CE +DEC + P GG+C + V Y C+CP G G C
Sbjct: 568 CACAPGY----TGTRCESQVDECRSQP-CRHGGKCLDLVDKYLCRCPSG----TTGVNC- 617
Query: 330 DVRPGYCYT-ALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKL 388
+V C + T G C + I + C C PG T L
Sbjct: 618 EVNIDDCASNPCTFGVCRD----GINRYDCVC------QPGFT--------------GPL 653
Query: 389 CSVPMVIPGRPEYPPPPLGPIPPVLPVPPGF----PPGPQIPVPRPPVEYLYPSREPPRV 444
C+V + E P G + GF PPG P+ PP +P P
Sbjct: 654 CNVEI-----NECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPP---SHPCAHEP-- 703
Query: 445 LPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPC-AGGE 503
C +G C PG RC C G+ + + D CE PC AGG
Sbjct: 704 ---------------CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGT 748
Query: 504 CINNQGSYTCQCRAGYQ-------STLTRTEC---------------------------- 528
C ++ + C C G Q S T C
Sbjct: 749 CSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ 808
Query: 529 RDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNC-EDMDECSIRNMCLN-GM 586
+D+DEC +G C N GSF C C+ G+ G +C +D+++C N CLN G
Sbjct: 809 QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDCD-PNPCLNGGS 863
Query: 587 CINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVG 646
C + GSF C C PGF + R +D++EC C G C + S+ C C PG G
Sbjct: 864 CQDGVGSFSCSCLPGF---AGPRCARDVDEC-LSNPCGPGTCTDHVASFTCTCPPGYG-G 918
Query: 647 LDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQ----PCPAQ 702
+ S+C+ G G C+ V C C G CQ PC ++
Sbjct: 919 FHCEQDLPDCSPSSCFNG---GTCV----DGVNSFSCLCRPG--YTGAHCQHEADPCLSR 969
Query: 703 NSAEYQALCSSGPGMTSAGSDI---NECALDPDICPNGICEN-----LRGTYKCICNSGY 754
++ PG + +C D C C+N G Y C+C G+
Sbjct: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY-CLCPPGW 1028
Query: 755 EVDSTGKNCVDINECV------LNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDI 808
+ E L L GQC + S C CP+G + +++
Sbjct: 1029 SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG---RTGSHCEQEV 1085
Query: 809 DECESSPCIN-GVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININ 867
D C + PC + G C+ G ++CEC D C + + Q G I++
Sbjct: 1086 DPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDN----CEDDVDECASQPCQHGGSCIDLV 1141
Query: 868 GATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCV 927
L CS G C + + D CG G G +C NG CV
Sbjct: 1142 ARYL----CSCPPGTLGVLCEINEDD--CGPGPPLDSGPRC------------LHNGTCV 1183
Query: 928 NTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAA 987
+ G F+C CP G T + R C + +C G R C C G +
Sbjct: 1184 DLVGGFRCTCPPGYTGLRCEADINECRSGACHAAH-TRDCLQDPGGGFR---CLCHAGFS 1239
Query: 988 WGTEECEECPMRNTP-EYEELCPRGP---GFATKEITNGKPFFKDINECKMIPSLCTHGK 1043
+ P + P ++ C P G T +PF+ C+ + C +
Sbjct: 1240 GPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGP--RCERVARSCRELQ 1297
Query: 1044 ------CRNTIGSFKCRCDSGFALDSEERNCTDID---------ECRISPDLCGRGQCVN 1088
C+ T +C C G + S C C +P L G G C
Sbjct: 1298 CPVGVPCQQTPRGPRCACPPGLSGPS----CRSFPGSPPGASNASCAAAPCLHG-GSCRP 1352
Query: 1089 TP--GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRC--ECPPGH 1144
P F C C +G+ + E +P C C G RC EC
Sbjct: 1353 APLAPFFRCACAQGWTG--PRCEAPAAAPEVSEEP-RCPRAACQAKRGDQRCDREC---- 1405
Query: 1145 QLSPNISAC-IDINECELSA----HLCPNGRCVNLIGKYQC--ACNPGYHSTPDRLFCVD 1197
N C D +C LS C +C L +C AC S+P L+
Sbjct: 1406 ----NSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPAC-----SSPACLY--- 1453
Query: 1198 IDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDEC 1242
D GG E C YE C FA + C + +EC
Sbjct: 1454 -DNFDCHAGGRERTC---NPVYEKYCADHFADGRCDQGC-NTEEC 1493
Score = 45.4 bits (106), Expect = 8e-04
Identities = 46/158 (29%), Positives = 58/158 (36%), Gaps = 35/158 (22%)
Query: 51 DALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPN---------MCT 101
D L+ P G + C G+ P + P C G RP+ C
Sbjct: 1221 DCLQDP---GGGFRCLCHAGFSG-PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCH 1276
Query: 102 CPSGQIAPSCGSRSIQHCN-IRCMNGGSCSDD----HCLCQKGYIGTHC----GQPVCES 152
C P C R + C ++C G C C C G G C G P S
Sbjct: 1277 CAQPFWGPRC-ERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGAS 1335
Query: 153 G-------CLNGGRC----VAPN-RCACTYGFTGPQCE 178
CL+GG C +AP RCAC G+TGP+CE
Sbjct: 1336 NASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
>gi|18497288 latent transforming growth factor beta binding protein 3
isoform 2 [Homo sapiens]
Length = 1256
Score = 429 bits (1104), Expect = e-119
Identities = 308/1018 (30%), Positives = 426/1018 (41%), Gaps = 200/1018 (19%)
Query: 970 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 1029
P+ G + + CC S+G AWG +C +CP +Y + GP
Sbjct: 293 PLPGLTKQEDCCGSIGTAWGQSKCHKCPQL---QYTGVQKPGP----------------- 332
Query: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
R +G+ C G+ +C DI+EC + P +C G C+N
Sbjct: 333 --------------VRGEVGA---DCPQGYKR-LNSTHCQDINECAM-PGVCRHGDCLNN 373
Query: 1090 PGDFECKCDEGYESGFMMMKNCMDIDE--------------CQRDPLLCR---------- 1125
PG + C C G+ G + D E CQ PL R
Sbjct: 374 PGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQH-PLTTRLTRQLCCCSV 432
Query: 1126 ----GGVCHN--TEGS--YRCECPPG---HQLSPNISACIDINECELSAHLCPNGRCV-N 1173
G C T+G+ ++ CP G H L+ + + I E + S L P+G
Sbjct: 433 GKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSHQTLTIQ-GESDFSLFLHPDGPPKPQ 491
Query: 1174 LIGKYQCACNPGYHSTPDRLFCVDI---DECSIMNGGCETFCTNSEGSYECSCQPGFALM 1230
+ + P + +R D +E S+ T + E +P M
Sbjct: 492 QLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTM 551
Query: 1231 -------PDQRSCTDI--------DECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 1275
P RS +I DEC N NIC G+C P +Y C C G+ +
Sbjct: 552 RWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQH 611
Query: 1276 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTG--CTDINECEIGAHNC 1333
+ CVDVNEC+ P G C NT GS+ CHC+ GY G G C D+NEC H C
Sbjct: 612 RYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLC 670
Query: 1334 GKHAVCTNTAGSFKCSCSPGWIGDGIK---CTDLDECSNGTHMCSQHADCKNTMGSYRCL 1390
G C N G +KC+C PG+ + C D+DEC + + C+N GS++C+
Sbjct: 671 GDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSC--PDGKCENKPGSFKCI 728
Query: 1391 -CKEGYTGDGF-TCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDID 1448
C+ GY G C D++EC+E + C G C N PG +RC C G+ P+ DG++C D+D
Sbjct: 729 ACQPGYRSQGGGACRDVNECAEG-SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVD 787
Query: 1449 ECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGS 1508
EC ++C G C N PG F+C+C GY L R +C D++EC P CI G+C+NT GS
Sbjct: 788 ECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGS 847
Query: 1509 YICDCPPDFEL----------------------------------------NPTRV--GC 1526
Y C CP L PT+ GC
Sbjct: 848 YRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGC 907
Query: 1527 VDTRSGN----CYLDIRPRGDNGDTA-CSNEIGVGVSKASCCCSLGKAWGTPCEM--CPA 1579
+ + CYL+ DT C + + V++ CCCSLG WG CE+ CP
Sbjct: 908 EEVEQPHHKKECYLNF------DDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPV 961
Query: 1580 VNTSEYKILCPGGEGFRPNPITVIL-----EDIDECQELPG-LCQGGKCINTFGSFQCRC 1633
+++E+ LCP G+G+ + V DIDEC +C+ GKC+NT ++C C
Sbjct: 962 YSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYC 1021
Query: 1634 PTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM--- 1690
G+Y + + C DV+EC C G C NT G Y C C P C+
Sbjct: 1022 KQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEM 1081
Query: 1691 -----RRSLCYRNYYADNQTCDGELLFN-MTKKMCCCSYNIGRAWNKPCEQCPIPSTDEF 1744
RR +C+ D C G L +T CCC GR W C CP
Sbjct: 1082 ERAPERRDVCWSQRGEDGM-CAGPLAGPALTFDDCCCRQ--GRGWGAQCRPCPPRGAGSH 1138
Query: 1745 ATLCGSQRPGF--VIDIYTGLPV--------DIDECREIPGVCENGVCINMVGSFRCECP 1794
S+ F + G P D DECR C +G C+ G CECP
Sbjct: 1139 CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECP 1193
Query: 1795 VGFFYNDKLLVCEDIDEC----QNGPVCQRNAECINTAGSYRCDCKPGY-RFTSTGQC 1847
GF + C DIDEC Q G +C ++ C+NT+GS+RC CK G+ R G C
Sbjct: 1194 GGFQLDASRARCVDIDECRELNQRGLLC-KSERCVNTSGSFRCVCKAGFARSRPHGAC 1250
Score = 358 bits (919), Expect = 4e-98
Identities = 222/689 (32%), Positives = 309/689 (44%), Gaps = 127/689 (18%)
Query: 1766 DIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECI 1825
+ DECR +C +G C+ + C C G+ + + C D++EC+ P C+
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 1826 NTAGS--------------------------------------------YRCDCKPGYRF 1841
NT GS Y+C+C PGYR
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 693
Query: 1842 TSTGQ--CNDRNECQEIPNICSHGQCIDTVGSFYCL-CHTGFKTNDDQTMCLDINEC-ER 1897
++ C D +EC++ P+ C G+C + GSF C+ C G+++ C D+NEC E
Sbjct: 694 KASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECAEG 751
Query: 1898 DACGNGTCRNTIGSFNCRCNHGFI-LSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQC 1956
C G C N GSF C C G+ C+DVDEC + G++C NG C NT GSFQC
Sbjct: 752 SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA--GDVCDNGICSNTPGSFQC 809
Query: 1957 QCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDID 2015
QC GY ++ D C DI+EC P C G C N +GSYRC+CP G+ L KC+DID
Sbjct: 810 QCLSGYHLSRDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDID 868
Query: 2016 ECVEEPEIC-ALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSY----CYAKFEGGK- 2069
EC ++P +C G C N +GS+ C+C EGF+ + C+++ + CY F+
Sbjct: 869 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVF 928
Query: 2070 CSSPKSRNHSKQECCCALKGEGWGDPCEL--CPTEPDEAFRQICPYGSGIIVGPDDSAV- 2126
C S + N ++QECCC+L G GWGD CE+ CP F +CP G G D++ V
Sbjct: 929 CDSVLATNVTQQECCCSL-GAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYT--QDNNIVN 985
Query: 2127 -------DMDECK--EPDVCKHGQCINTDGSYRCECPFGYILAGN--ECVDTDECSVGNP 2175
D+DEC ++CK G+C+NT Y C C G+ GN ECVD DEC +
Sbjct: 986 YGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN 1045
Query: 2176 CGNGTCKNVIGGFECTCEEGFEPGP-MMTCEDINECAQNPL-------------LCAFRC 2221
C NG C+N GG+ C C E P C E + P +CA
Sbjct: 1046 CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPL 1105
Query: 2222 VNTYGSY-ECKCPVGYVLREDRRMC-------------------------------KDED 2249
++ +C C G R C +DED
Sbjct: 1106 AGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDED 1165
Query: 2250 ECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQ---TKPGICENGR 2306
EE +C C G +C C G+Q CVD +EC+ + +C++ R
Sbjct: 1166 SSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER 1225
Query: 2307 CLNTRGSYTCECNDGFTASPNQDECLDNR 2335
C+NT GS+ C C GF S C+ R
Sbjct: 1226 CVNTSGSFRCVCKAGFARSRPHGACVPQR 1254
Score = 356 bits (913), Expect = 2e-97
Identities = 219/733 (29%), Positives = 317/733 (43%), Gaps = 119/733 (16%)
Query: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
+ +EC++ ++C HG+C + C C+ G+ + R C D++EC P GRG C+
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 1088 NTPGDFECKCDEGYESGF-MMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1146
NT G + C C+ GY ++C+D++EC + L GG C N G Y+C C PG++L
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 693
Query: 1147 -SPNISACIDINECELSAHLCPNGRCVNLIGKYQC-ACNPGYHSTPDRLFCVDIDECSIM 1204
+ C DI+EC CP+G+C N G ++C AC PGY S C D++EC+
Sbjct: 694 KASRPPVCEDIDECR-DPSSCPDGKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECAEG 751
Query: 1205 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264
+ +C N GS+ C+C G+A PD RSC D+DECE ++CD G C+N PG ++C
Sbjct: 752 SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDNGICSNTPGSFQCQ 810
Query: 1265 CYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDIN 1324
C G+ S D C D++ECD P C+ G C NT GS+ C C G+ G+ C DI+
Sbjct: 811 CLSGYHLSRDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVGGRK-CQDID 868
Query: 1325 ECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCTDLDE---------------- 1366
EC C H C N GS+ C C G+ D C ++++
Sbjct: 869 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVF 928
Query: 1367 CSN--GTHMCSQHADCKNTMG----------------SYRCLCKE--GYTGDGFTCT--- 1403
C + T++ Q C G + LC + GYT D
Sbjct: 929 CDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGI 988
Query: 1404 ----DLDECS-ENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVF 1458
D+DEC +C G+C+N GY C C GF + C D+DEC + C
Sbjct: 989 PAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRN 1048
Query: 1459 GTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFE 1518
G C N G +RC C E +P C P + E
Sbjct: 1049 GVCENTRGGYRCACTPPAEY--------------------------SPAQRQCLSPEEME 1082
Query: 1519 LNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEI-GVGVSKASCCCSLGKAWGTPCEMC 1577
P R C+ RG++G C+ + G ++ CCC G+ WG C C
Sbjct: 1083 RAP-------ERRDVCW---SQRGEDG--MCAGPLAGPALTFDDCCCRQGRGWGAQCRPC 1130
Query: 1578 PAVNTSEYKILCPGGE--------------GFRPNPITVILEDIDECQELPGLCQGGKCI 1623
P + CP + G P ED DEC+ C G+C+
Sbjct: 1131 PPRGAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCV 1182
Query: 1624 NTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG----ICGPGTCYNTVGNYTCICPPDYM 1679
G C CP G+ L+ C D++EC +C C NT G++ C+C +
Sbjct: 1183 PRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFA 1242
Query: 1680 QVNGGNNCMDMRR 1692
+ C+ RR
Sbjct: 1243 RSRPHGACVPQRR 1255
Score = 355 bits (912), Expect = 3e-97
Identities = 234/730 (32%), Positives = 322/730 (44%), Gaps = 91/730 (12%)
Query: 1963 EVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL--QNEKCEDIDECVEE 2020
E+AP T D EC L C G C Y C C PGY Q+ C D++EC E
Sbjct: 566 EIAPTQVTETD--ECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAE 623
Query: 2021 PEICALGTCSNTEGSFKCLCPEGFSL--SSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNH 2078
P G C NT GS+ C C G+ L + GR C DL +C+ P
Sbjct: 624 PCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLN-----------ECAKPH---- 668
Query: 2079 SKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCK 2138
L G+G C P ++ C G + D+DEC++P C
Sbjct: 669 --------LCGDGG-----FCINFPGH-YKCNCYPGYRLKASRPPVCEDIDECRDPSSCP 714
Query: 2139 HGQCINTDGSYRC-ECPFGY-ILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGF 2196
G+C N GS++C C GY G C D +EC+ G+PC G C+N+ G F CTC +G+
Sbjct: 715 DGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGY 774
Query: 2197 EPGPM-MTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGK 2255
P P +C D++EC + C NT GS++C+C GY L DR C+D DEC+
Sbjct: 775 APAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD--- 831
Query: 2256 HDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC-ENGRCLNTRGSY 2314
+C N G+Y C+C G+ R G C D +EC P +C +G C N +GSY
Sbjct: 832 FPAACIGGDCINTNGSYRCLCPQGH-RLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSY 890
Query: 2315 TCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQI---GSSNRNPVTKSECCCDGGRGW 2371
C C++GFT + +Q C + + + E N S VT+ ECCC G GW
Sbjct: 891 VCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW 950
Query: 2372 GPHCEI--CPFQGTVAFKKLCPHGRGFMTNG----------ADIDECKVI-HDVCRNGEC 2418
G HCEI CP + F LCP G+G+ + DIDEC + ++C+ G+C
Sbjct: 951 GDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKC 1010
Query: 2419 VNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQE 2478
VN + Y C CK G+ D CVD++EC N +C+NT G Y+C+C
Sbjct: 1011 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSP 1070
Query: 2479 DGRSC---KDLDECATKQHNC------QFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECT 2529
R C ++++ ++ C +C + G P T C
Sbjct: 1071 AQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAG------PALTFDDCCCRQGRGWG 1124
Query: 2530 SDINLCGSKGICQNTPGS--------FTCECQRGFSLDQTGSSCEDVDECEGNHRCQHG- 2580
+ C +G + P S T G SS ED DEC RC G
Sbjct: 1125 AQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDEC----RCVSGR 1180
Query: 2581 CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAH----ICGGASCHNTLGSYKCMCPAG 2636
C GG C CP G+ +CVD +EC + +C C NT GS++C+C AG
Sbjct: 1181 CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 1240
Query: 2637 FQYEQFSGGC 2646
F + G C
Sbjct: 1241 FARSRPHGAC 1250
Score = 344 bits (882), Expect = 8e-94
Identities = 236/735 (32%), Positives = 326/735 (44%), Gaps = 133/735 (18%)
Query: 1318 TGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIK--CTDLDECSNGTHMCS 1375
T T+ +EC + + CG H C + C C+PG+ C D++EC C
Sbjct: 570 TQVTETDECRLNQNICG-HGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE--AEPCG 626
Query: 1376 Q-HADCKNTMGSYRCLCKEGYT----GDGFTCTDLDECSENLNLCGNGQ-CLNAPGGYRC 1429
C NT GSY C C GY G +C DL+EC++ +LCG+G C+N PG Y+C
Sbjct: 627 PGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKP-HLCGDGGFCINFPGHYKC 685
Query: 1430 ECDMGF-VPSADGKACEDIDECSLPNICVFGTCHNLPGLFRC-ECEIGYELDRSGGNCTD 1487
C G+ + ++ CEDIDEC P+ C G C N PG F+C C+ GY + GG C D
Sbjct: 686 NCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR-SQGGGACRD 744
Query: 1488 VNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDT 1547
VNEC + + C G C N PGS+ C C + P C+D +D GD D
Sbjct: 745 VNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD-------VDECEAGDVCDN 797
Query: 1548 A-CSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILED 1606
CSN G C+ + S + C ED
Sbjct: 798 GICSNTPG----------------SFQCQCLSGYHLSRDRSHC---------------ED 826
Query: 1607 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC-ETPGICGP-GTCY 1664
IDEC + P C GG CINT GS++C CP G+ L R C D++EC + P +C P G C
Sbjct: 827 IDEC-DFPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACK 884
Query: 1665 NTVGNYTCICPPDYMQVNGGNNCMDMR----RSLCYRNYYADNQTCDGELLFNMTKKMCC 1720
N G+Y C+C + + C ++ + CY N+ D CD L N+T++ CC
Sbjct: 885 NLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNF-DDTVFCDSVLATNVTQQECC 943
Query: 1721 CSYNIGRAWNKPCE--QCPIPSTDEFATLCGSQRPGFVID---IYTGLPV--DIDECREI 1773
CS +G W CE CP+ S+ EF +LC + G+ D + G+P DIDEC
Sbjct: 944 CS--LGAGWGDHCEIYPCPVYSSAEFHSLCPDGK-GYTQDNNIVNYGIPAHRDIDECMLF 1000
Query: 1774 PG-VCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYR 1832
+C+ G C+N + C C GF+Y+ LL C D+DEC + C RN C NT G YR
Sbjct: 1001 GSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNC-RNGVCENTRGGYR 1059
Query: 1833 CDCKPGYRFT-STGQCNDRNECQEIP---NIC-----SHGQCIDTVGS-----FYCLCH- 1877
C C P ++ + QC E + P ++C G C + C C
Sbjct: 1060 CACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQ 1119
Query: 1878 -------------------------------------TGFKTNDDQTMCLDINECERDAC 1900
G D+ + D +EC C
Sbjct: 1120 GRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR---C 1176
Query: 1901 GNGTCRNTIGSFNCRCNHGFILSHNN-DCIDVDECASGN--GNLCRNGQCINTVGSFQCQ 1957
+G C G C C GF L + C+D+DEC N G LC++ +C+NT GSF+C
Sbjct: 1177 VSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCV 1236
Query: 1958 CNEGYEVAPDGRTCV 1972
C G+ + CV
Sbjct: 1237 CKAGFARSRPHGACV 1251
Score = 343 bits (879), Expect = 2e-93
Identities = 278/1012 (27%), Positives = 389/1012 (38%), Gaps = 254/1012 (25%)
Query: 184 GPCFT-VISNQMCQGQLSGIVCTKTLCCATVGRAWGHP-CEMCPAQPHPCRRGFIPNIRT 241
G CF + Q C + + CC ++G AWG C CP + T
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQY-----------T 325
Query: 242 GACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHK-LNEVSQKCEDIDECSTIPGICE 300
G + PG +G VG+ CP G+K LN S C+DI+EC+ +PG+C
Sbjct: 326 GVQK--------PGPVRG-----EVGA---DCPQGYKRLN--STHCQDINECA-MPGVCR 366
Query: 301 GGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP---GYCYTALT-NGRCSNQLPQSITKM 356
G+C N SY C CPPG P T+CI +P C+ ++ +C + L +T+
Sbjct: 367 HGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQ 426
Query: 357 QCCCDAGRCW--------SPGVTVAPEMCP---------------IRATEDFNKLC---- 389
CCC G+ W + G E+CP I+ DF+
Sbjct: 427 LCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDG 486
Query: 390 -SVPMVIPGRPEYPPPPL-----------GPIP---------PVLPVPPGFPPGPQIPVP 428
P +P P PPP P+ P P P I P
Sbjct: 487 PPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRP 546
Query: 429 RPP-----VEYLYPSREPPRVLPVNV--TDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQ 481
PP + L PSR + P V TD C+L + +C +G C+P P C CN G++
Sbjct: 547 SPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYR 606
Query: 482 LDLRGE-CIDVDECEKNPCAGGE--CINNQGSYTCQCRAGYQSTLTR--TECRDIDECLQ 536
+ C+DV+ECE PC G C+N GSY C C GY+ + C D++EC +
Sbjct: 607 SHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK 666
Query: 537 NGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN-CEDMDECSIRNMCLNGMCINEDGSFK 595
+ G CIN G + C C G+ + CED+DEC + C +G C N+ GSFK
Sbjct: 667 PHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFK 726
Query: 596 CI-CKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
CI C+PG++ + G C+D+NEC C G C N GS+RC C G A DGR C+D
Sbjct: 727 CIACQPGYR-SQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 785
Query: 655 THMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG 714
C G C + S C + Y C + ++ A C G
Sbjct: 786 V---DECEAG---DVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGG 839
Query: 715 PGMTSAGS------------------DINECALDPDIC-PNGICENLRGTYKCICNSGYE 755
+ + GS DI+EC+ DP +C P+G C+NL+G+Y C+C+ G+
Sbjct: 840 DCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 899
Query: 756 VDSTGKNCVDI------NECVLN---SLLCDNGQCRN----------------------- 783
C ++ EC LN ++ CD+ N
Sbjct: 900 PTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPC 959
Query: 784 ---TPGSFVCTCPKGFIYKPD-------LKTCEDIDEC---------------------- 811
+ F CP G Y D + DIDEC
Sbjct: 960 PVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYEC 1019
Query: 812 ----------------------ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIE-- 847
+ S C NGVC+N+ G + C C+ + P + C+
Sbjct: 1020 YCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPE 1079
Query: 848 ------TIKGTCW-QTVIDGRCEININGATLK-SQCCSSLGAAWGSPCTLC--------- 890
+ CW Q DG C + G L CC G WG+ C C
Sbjct: 1080 EMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHC 1139
Query: 891 -----------QVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPS 939
P+ R + + ED DEC C +G CV G C+CP
Sbjct: 1140 PTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPG 1194
Query: 940 GMTLDATGRICLDI----RLETCFLRYEDEECTLPIAGRHRMDACCCSVGAA 987
G LDA+ C+DI L L + E C + +G R C C G A
Sbjct: 1195 GFQLDASRARCVDIDECRELNQRGLLCKSERC-VNTSGSFR---CVCKAGFA 1242
Score = 338 bits (866), Expect = 6e-92
Identities = 232/729 (31%), Positives = 323/729 (44%), Gaps = 140/729 (19%)
Query: 1846 QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC--GNG 1903
Q + +EC+ NIC HG+C+ + C C+ G++++ C+D+NECE + C G G
Sbjct: 571 QVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG 630
Query: 1904 TCRNTIGSFNCRCNHGFIL---SHNNDCIDVDECASGNGNLCRNGQ-CINTVGSFQCQCN 1959
C NT GS+NC CN G+ L + C+D++ECA +LC +G CIN G ++C C
Sbjct: 631 ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA--KPHLCGDGGFCINFPGHYKCNCY 688
Query: 1960 EGYEV-APDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCI-CPPGYSLQ-NEKCEDIDE 2016
GY + A C DI+EC +P C G C+N GS++CI C PGY Q C D++E
Sbjct: 689 PGYRLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 747
Query: 2017 CVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSR 2076
C E C+ G C N GSF+C C +G++ + GR C D+ +C +
Sbjct: 748 CAEGSP-CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDV-----------DECEA---- 791
Query: 2077 NHSKQECCCALKGEGWGDPCE--LCPTEPDEAFRQICPYGSGIIVGPDDS-AVDMDECKE 2133
GD C+ +C P +F+ C SG + D S D+DEC
Sbjct: 792 ----------------GDVCDNGICSNTPG-SFQ--CQCLSGYHLSRDRSHCEDIDECDF 832
Query: 2134 PDVCKHGQCINTDGSYRCECPFGY-ILAGNECVDTDECSVGNP--CGNGTCKNVIGGFEC 2190
P C G CINT+GSYRC CP G+ ++ G +C D DECS +G CKN+ G + C
Sbjct: 833 PAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVC 892
Query: 2191 TCEEGFEP-GPMMTCEDI------NECAQN---PLLCAFRCVNTYGSYECKCPVG----- 2235
C+EGF P CE++ EC N + C EC C +G
Sbjct: 893 VCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGD 952
Query: 2236 ---------YVLREDRRMC--------------------KDEDECE-EGKHDCTEKQMEC 2265
Y E +C +D DEC G C K+ +C
Sbjct: 953 HCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEIC--KEGKC 1010
Query: 2266 KNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTAS 2325
N Y C C G+ + CVD +EC + C NG C NTRG Y C C S
Sbjct: 1011 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGGYRCACTPPAEYS 1069
Query: 2326 PNQDECLD--------NREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEI 2377
P Q +CL R C+++ ++ G +T +CCC GRGWG C
Sbjct: 1070 PAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRP 1129
Query: 2378 CPFQGTVAFKKLCPHG-------------------RGFMTNGADIDECKVIHDVCRNGEC 2418
CP +G + CP R ++ D DEC+ C +G C
Sbjct: 1130 CPPRGAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRC 1181
Query: 2419 VNDRGSYHCICKTGYTPDITGTSCVDLNEC---NQAPKPC-NFICKNTEGSYQCSCPKGY 2474
V G C C G+ D + CVD++EC NQ C + C NT GS++C C G+
Sbjct: 1182 VPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGF 1241
Query: 2475 ILQEDGRSC 2483
+C
Sbjct: 1242 ARSRPHGAC 1250
Score = 307 bits (787), Expect = 9e-83
Identities = 228/762 (29%), Positives = 315/762 (41%), Gaps = 176/762 (23%)
Query: 288 DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVR--------PGYCYTA 339
+ DEC IC GEC Y C C PG+ + P C+DV PG
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPG----- 628
Query: 340 LTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRP 399
G C N + C C+ G G R+ D N+ C+ P +
Sbjct: 629 --RGICMN----TGGSYNCHCNRGYRLHVGAGG-------RSCVDLNE-CAKPHLC---- 670
Query: 400 EYPPPPLGPIPPVLPVPPGFP----PGPQIPVPRPPV-EYLYPSREPPRVLPVNVTDYCQ 454
G + P + PG ++ RPPV E + R+P
Sbjct: 671 -------GDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS----------- 712
Query: 455 LVRYLCQNGRCIPTPGSCRC-ECNKGFQLDLRGECIDVDEC-EKNPCAGGECINNQGSYT 512
C +G+C PGS +C C G++ G C DV+EC E +PC+ G C N GS+
Sbjct: 713 -----CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFR 767
Query: 513 CQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCED 572
C C GY C D+DEC + G +C+NG C NT GSF C C +G+H++RD +CED
Sbjct: 768 CTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCED 826
Query: 573 MDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICM-NGRCVN 630
+DEC C+ G CIN +GS++C+C G +L GR C+DI+EC + P +C+ +G C N
Sbjct: 827 IDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGACKN 885
Query: 631 TDGSYRCECFPGLAVGLDGRVCVDT---HMRSTCYGGYKRGQ-CIKPLFGAVTKSECCCA 686
GSY C C G D C + H + CY + C L VT+ ECCC
Sbjct: 886 LQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCC- 944
Query: 687 STEYAFGEPCQ--PCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRG 744
S +G+ C+ PCP +SAE+ +LC G G T + +N
Sbjct: 945 SLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVN------------------- 985
Query: 745 TYKCICNSGYEVDSTGKNCVDINECVL-NSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLK 803
Y + + DI+EC+L S +C G+C NT + C C +GF Y +L
Sbjct: 986 ---------YGIPAHR----DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLL 1032
Query: 804 TCEDIDEC-ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETI--------KGTCW 854
C D+DEC + S C NGVC+N+ G + C C+ + P + C+ + CW
Sbjct: 1033 ECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCW 1092
Query: 855 -QTVIDGRCEININGATLK-SQCCSSLGAAWG------------SPCTLCQVDP------ 894
Q DG C + G L CC G WG S C Q +
Sbjct: 1093 SQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDT 1152
Query: 895 ------------------------ICGKGYSRIKGTQCE---------------DIDECE 915
+ G+ R G CE DIDEC
Sbjct: 1153 SPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECR 1212
Query: 916 VFPG---VCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 954
+CK+ CVNT GSF+C C +G C+ R
Sbjct: 1213 ELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1254
Score = 266 bits (681), Expect = 2e-70
Identities = 208/704 (29%), Positives = 283/704 (40%), Gaps = 141/704 (20%)
Query: 903 IKGTQCEDIDECEVFPGVCKN--------------------------------------- 923
I TQ + DEC + +C +
Sbjct: 567 IAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCG 626
Query: 924 ---GLCVNTRGSFKCQCPSGMTL--DATGRICLDIRLETCFLRY--EDEECTLPIAGRHR 976
G+C+NT GS+ C C G L A GR C+D L C + D + G ++
Sbjct: 627 PGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVD--LNECAKPHLCGDGGFCINFPGHYK 684
Query: 977 MDACCCSVG---------AAWGTEECEE---CP---MRNTPEYEELCPRGPGFATKEITN 1021
C C G +EC + CP N P + PG+ ++
Sbjct: 685 ---CNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQ---- 737
Query: 1022 GKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC 1081
G +D+NEC S C+ G C N GSF+C C G+A + R+C D+DEC + D+C
Sbjct: 738 GGGACRDVNECAE-GSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECE-AGDVC 795
Query: 1082 GRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP 1141
G C NTPG F+C+C GY +C DIDEC P C GG C NT GSYRC CP
Sbjct: 796 DNGICSNTPGSFQCQCLSGYHLS-RDRSHCEDIDECD-FPAACIGGDCINTNGSYRCLCP 853
Query: 1142 PGHQLSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDID- 1199
GH+L C DI+EC LC P+G C NL G Y C C+ G+ T D+ C +++
Sbjct: 854 QGHRLVGG-RKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 912
Query: 1200 -----ECSIMNGG---CETFCTNSEGSYECSCQPG--------------------FALMP 1231
EC + C++ + EC C G +L P
Sbjct: 913 PHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCP 972
Query: 1232 DQRSCT--------------DIDECE-DNPNICDGGQCTNIPGEYRCLCYDGFMASEDMK 1276
D + T DIDEC IC G+C N Y C C GF ++
Sbjct: 973 DGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLL 1032
Query: 1277 TCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHN---C 1333
CVDV+EC L+ + C +G CENT+G + C C + C E E C
Sbjct: 1033 ECVDVDEC-LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVC 1091
Query: 1334 ----GKHAVC----TNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMG 1385
G+ +C A +F C G G +C G+H + ++ +
Sbjct: 1092 WSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWD 1151
Query: 1386 SYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE 1445
+ L + + + D DEC C +G+C+ PGG CEC GF A C
Sbjct: 1152 TSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCV 1206
Query: 1446 DIDECSLPN----ICVFGTCHNLPGLFRCECEIGYELDRSGGNC 1485
DIDEC N +C C N G FRC C+ G+ R G C
Sbjct: 1207 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1250
Score = 260 bits (665), Expect = 1e-68
Identities = 240/906 (26%), Positives = 341/906 (37%), Gaps = 181/906 (19%)
Query: 1910 GSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGR 1969
G C G+ ++ C D++ECA +CR+G C+N GS++C C G+ + P
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECAMPG--VCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 1970 TCV-----DINEC--LLEPRKCAPGTCQNLDGSYRCICPPG--YSLQNEKCEDIDECVEE 2020
C+ + + C L+ P C C G + + ++C D
Sbjct: 393 QCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRC-PTDGTAAF 451
Query: 2021 PEICALGTCSNTEGSFKCLCPEG---FSL---SSSGRRCQDLRMSYCYA-------KFEG 2067
EIC G + S + L +G FSL + Q L S A + G
Sbjct: 452 KEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERG 511
Query: 2068 GKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFR----QICPYGSGIIVGPDD 2123
SP S S Q+ EL R + P S + + P
Sbjct: 512 VTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAP-T 570
Query: 2124 SAVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYILAGNE--CVDTDECSVGNPC--GN 2178
+ DEC+ ++C HG+C+ Y C C GY CVD +EC PC G
Sbjct: 571 QVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE-AEPCGPGR 629
Query: 2179 GTCKNVIGGFECTCEEGFE---PGPMMTCEDINECAQNPLLCAFR--CVNTYGSYECKCP 2233
G C N G + C C G+ +C D+NECA+ P LC C+N G Y+C C
Sbjct: 630 GICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCNCY 688
Query: 2234 VGYVLREDR-RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI-CGPGYQRRPDGEGCVD 2291
GY L+ R +C+D DEC + C + +C+N G++ CI C PGY R G C D
Sbjct: 689 PGYRLKASRPPVCEDIDECRD-PSSCPDG--KCENKPGSFKCIACQPGY-RSQGGGACRD 744
Query: 2292 ENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIG 2351
NEC + C G C N GS+ C C G+ +P+ CLD E C ++C G
Sbjct: 745 VNEC-AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDE--C---EAGDVCDNG 798
Query: 2352 SSNRNPVTKSECCCDGGRGWG---PHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKV 2408
+ P +C C G HCE DIDEC
Sbjct: 799 ICSNTP-GSFQCQCLSGYHLSRDRSHCE-------------------------DIDECD- 831
Query: 2409 IHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC--NFICKNTEGSY 2466
C G+C+N GSY C+C G+ + G C D++EC+Q P C + CKN +GSY
Sbjct: 832 FPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSY 890
Query: 2467 QCSCPKGYILQEDGRSCKDLDECATKQH---------NCQFLCVNTIGGFTCKCPPG--- 2514
C C +G+ +D C+++++ K+ C + + C C G
Sbjct: 891 VCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW 950
Query: 2515 -------------FTQHHTSCIDNNECTSDINLCG--------------------SKGIC 2541
+ H+ C D T D N+ +G C
Sbjct: 951 GDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKC 1010
Query: 2542 QNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHY 2600
NT + C C++GF D C DVDEC C++G C+N GGYRC+C
Sbjct: 1011 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSP 1070
Query: 2601 QWNQCVDENE----------CLSAH----ICGGASCHNTLGSYKCMCPAGFQYEQFSGGC 2646
QC+ E C S +C G L C C G + C
Sbjct: 1071 AQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPC 1130
Query: 2647 ---------------------------------QDINECGSAQAPCSYG-CSNTEGGYLC 2672
+D +E S + C G C GG +C
Sbjct: 1131 PPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVC 1190
Query: 2673 GCPPGY 2678
CP G+
Sbjct: 1191 ECPGGF 1196
Score = 239 bits (609), Expect = 4e-62
Identities = 170/546 (31%), Positives = 236/546 (43%), Gaps = 57/546 (10%)
Query: 2184 VIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRR 2243
V G C +G++ C+DINECA + C+N GSY C CP G+ L R
Sbjct: 333 VRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 2244 MC-KDEDECEEGKHDCTEKQMECKNLIGT----YMCICGPGYQRRPDGEGCVDENECQTK 2298
C D+ E + + +C++ + T +C C G + C + K
Sbjct: 393 QCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFK 452
Query: 2299 PGICENGR---CLNTRGSYTCECNDGFTA---------------SPNQ---DECLDNREG 2337
IC G+ L + + T + F+ SP+Q E + G
Sbjct: 453 E-ICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERG 511
Query: 2338 YCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEIC--PFQGTVA-FKKLCPHGR 2394
+ + S+ T P+ E+ P T+ F P R
Sbjct: 512 VTTDSPVSEERSVQQSHPTATTTPA---------RPYPELISRPSPPTMRWFLPDLPPSR 562
Query: 2395 GFM----TNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQ 2450
+ T + DEC++ ++C +GECV Y C C GY CVD+NEC
Sbjct: 563 SAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA 622
Query: 2451 AP-KPCNFICKNTEGSYQCSCPKGYILQ--EDGRSCKDLDECATKQHNCQF--LCVNTIG 2505
P P IC NT GSY C C +GY L GRSC DL+ECA K H C C+N G
Sbjct: 623 EPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGGFCINFPG 681
Query: 2506 GFTCKCPPGF---TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC-ECQRGFSLDQT 2561
+ C C PG+ C D +EC D + C G C+N PGSF C CQ G+ Q
Sbjct: 682 HYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPD-GKCENKPGSFKCIACQPGYR-SQG 738
Query: 2562 GSSCEDVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGA 2620
G +C DV+EC C G C+N+ G +RC+C QGY C+D +EC + +C
Sbjct: 739 GGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNG 798
Query: 2621 SCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFR 2680
C NT GS++C C +G+ + C+DI+EC A C NT G Y C CP G+
Sbjct: 799 ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRL 858
Query: 2681 IGQGHC 2686
+G C
Sbjct: 859 VGGRKC 864
Score = 235 bits (600), Expect = 4e-61
Identities = 195/699 (27%), Positives = 266/699 (38%), Gaps = 205/699 (29%)
Query: 722 SDINECALDPDICPNGICENLRGTYKCICNSGY--------------------------- 754
++ +EC L+ +IC +G C Y C CN GY
Sbjct: 573 TETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGIC 632
Query: 755 -----------------EVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFI 797
V + G++CVD+NEC L D G C N PG + C C G+
Sbjct: 633 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 692
Query: 798 YKPDL-KTCEDIDEC-ESSPCINGVCKNSPGSFIC-------------------ECSSES 836
K CEDIDEC + S C +G C+N PGSF C EC+ S
Sbjct: 693 LKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS 752
Query: 837 TLDPTKTICIETIKG----TCWQ---TVIDGRCEININGATLKSQC----CSSLGAAWGS 885
P E + G TC Q DGR ++++ C CS+ ++
Sbjct: 753 PCSPG---WCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQC 809
Query: 886 PCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDA 945
C + G SR + + CEDIDEC+ FP C G C+NT GS++C CP G L
Sbjct: 810 QC-------LSGYHLSRDR-SHCEDIDECD-FPAACIGGDCINTNGSYRCLCPQGHRL-V 859
Query: 946 TGRICLDI-----------------------------------------------RLETC 958
GR C DI + C
Sbjct: 860 GGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKEC 919
Query: 959 FLRYEDEE-CTLPIAGRHRMDACCCSVGAAWGTEECE--ECPMRNTPEYEELCPRGPGFA 1015
+L ++D C +A CCCS+GA WG + CE CP+ ++ E+ LCP G G+
Sbjct: 920 YLNFDDTVFCDSVLATNVTQQECCCSLGAGWG-DHCEIYPCPVYSSAEFHSLCPDGKGYT 978
Query: 1016 TKE--ITNGKPFFKDINECKMIPS-LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDID 1072
+ G P +DI+EC + S +C GKC NT ++C C GF D C D+D
Sbjct: 979 QDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVD 1038
Query: 1073 ECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPL---------- 1122
EC + C G C NT G + C C E + C+ +E +R P
Sbjct: 1039 EC-LDESNCRNGVCENTRGGYRCACTPPAEYS-PAQRQCLSPEEMERAPERRDVCWSQRG 1096
Query: 1123 ---LCRGGV-----------CHNTEG-SYRCE-CPP------------------------ 1142
+C G + C G +C CPP
Sbjct: 1097 EDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLL 1156
Query: 1143 -GHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC 1201
G S+ D +EC C +GRCV G C C G+ R CVDIDEC
Sbjct: 1157 LGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDEC 1211
Query: 1202 SIMNGG---CET-FCTNSEGSYECSCQPGFALMPDQRSC 1236
+N C++ C N+ GS+ C C+ GFA +C
Sbjct: 1212 RELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1250
Score = 234 bits (598), Expect = 7e-61
Identities = 173/545 (31%), Positives = 227/545 (41%), Gaps = 91/545 (16%)
Query: 2206 DINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQME 2264
+ +EC N +C CV Y C C GY R C D +ECE C +
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA--EPCGPGRGI 631
Query: 2265 CKNLIGTYMCICGPGYQRR--PDGEGCVDENECQTKPGIC-ENGRCLNTRGSYTCECNDG 2321
C N G+Y C C GY+ G CVD NEC KP +C + G C+N G Y C C G
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKCNCYPG 690
Query: 2322 FTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQ 2381
+ ++ +C+ R+P + C DG CE P
Sbjct: 691 YRLKASRPP----------------VCEDIDECRDPSS----CPDG------KCENKPG- 723
Query: 2382 GTVAFKKL-CPHGRGFMTNGA--DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDIT 2438
+FK + C G GA D++EC C G C N GS+ C C GY P
Sbjct: 724 ---SFKCIACQPGYRSQGGGACRDVNECAE-GSPCSPGWCENLPGSFRCTCAQGYAPAPD 779
Query: 2439 GTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF 2498
G SC+D++EC N IC NT GS+QC C GY L D C+D+DEC
Sbjct: 780 GRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGG 839
Query: 2499 LCVNTIGGFTCKCPPGFTQ-HHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFS 2557
C+NT G + C CP G C D +EC+ D +LC G C+N GS+ C C GF+
Sbjct: 840 DCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 899
Query: 2558 LDQTGSSCEDVDECEGNHRC--------------------QHGCQNIIGG-------YRC 2590
Q CE+V++ C Q C ++ G Y C
Sbjct: 900 PTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPC 959
Query: 2591 S----------CP--QGYLQ-----HYQWNQCVDENECL--SAHICGGASCHNTLGSYKC 2631
CP +GY Q +Y D +EC+ + IC C NT Y+C
Sbjct: 960 PVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYEC 1019
Query: 2632 MCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGC-PPGYFRIGQGHCVSG 2689
C GF Y+ C D++EC ++ C G C NT GGY C C PP + Q C+S
Sbjct: 1020 YCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSP 1078
Query: 2690 MGMGR 2694
M R
Sbjct: 1079 EEMER 1083
Score = 220 bits (561), Expect = 1e-56
Identities = 191/702 (27%), Positives = 260/702 (37%), Gaps = 171/702 (24%)
Query: 55 GPNVC---GSRYNAYCCPGWKTLPGG--------NQCIVPICRHSCGDG-FCSR---PNM 99
G +C G YN +C G++ G N+C P H CGDG FC
Sbjct: 628 GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKP---HLCGDGGFCINFPGHYK 684
Query: 100 CTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHC----------LCQKGYIGTHCGQPV 149
C C G + + + C + SC D C CQ GY G
Sbjct: 685 CNCYPGYRLKASRPPVCEDID-ECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACR 743
Query: 150 CESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGP----CFTVISNQMCQGQLSGIVCT 205
+ C G C +P C G C + Y P C V C+ +G VC
Sbjct: 744 DVNECAEGSPC-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLDV---DECE---AGDVCD 796
Query: 206 KTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINT 265
+C T G C+ C G+ + C+D+DEC P C GG+CINT
Sbjct: 797 NGICSNTPG---SFQCQ--------CLSGYHLSRDRSHCEDIDECD-FPAACIGGDCINT 844
Query: 266 VGSFECKCPAGHKLNEVSQKCEDIDECSTIPGIC-EGGECTNTVSSYFCKCPPGFYTSPD 324
GS+ C CP GH+L +KC+DIDECS P +C G C N SY C C GF + D
Sbjct: 845 NGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQD 903
Query: 325 GTRCIDVRPGY----CYTALTNGR-CSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPI 379
C +V + CY + C + L ++T+ +CCC G W + P CP+
Sbjct: 904 QHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYP--CPV 961
Query: 380 RATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSR 439
++ +F+ LC P G V Y P+
Sbjct: 962 YSSAEFHSLC------------------------------PDGKGYTQDNNIVNYGIPAH 991
Query: 440 EPPRVLPVNVTDYCQLV-RYLCQNGRCIPTPGSCRCECNKGFQLDLR-GECIDVDEC-EK 496
D C L +C+ G+C+ T C C +GF D EC+DVDEC ++
Sbjct: 992 RD--------IDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDE 1043
Query: 497 NPCAGGECINNQGSYTCQCRAGYQSTLTRTEC------------RDI------------- 531
+ C G C N +G Y C C + + + +C RD+
Sbjct: 1044 SNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAG 1103
Query: 532 ---------DECLQNGRICNNGR--------CINTDGSFHCVCN--------------AG 560
D+C C GR C HC + G
Sbjct: 1104 PLAGPALTFDDC-----CCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLG 1158
Query: 561 FHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETP 620
+ + ED DEC C++G C+ G C C GFQL + C DI+EC
Sbjct: 1159 KPPRDEDSSEEDSDEC----RCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECREL 1214
Query: 621 G----ICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMR 658
+C + RCVNT GS+RC C G A CV R
Sbjct: 1215 NQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRRR 1256
Score = 180 bits (456), Expect = 2e-44
Identities = 176/697 (25%), Positives = 257/697 (36%), Gaps = 155/697 (22%)
Query: 205 TKTLCCATVGRAWGHPCEMCPAQPH---PCRRGFIPNIRTGACQDVDECQAIPGLCQGGN 261
T+T C GH E P P C G+ + + C DV+EC+A P G
Sbjct: 573 TETDECRLNQNICGHG-ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGI 631
Query: 262 CINTVGSFECKCPAGHKLNEVS--QKCEDIDECSTIPGIC-EGGECTNTVSSYFCKCPPG 318
C+NT GS+ C C G++L+ + + C D++EC+ P +C +GG C N Y C C PG
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCNCYPG 690
Query: 319 FYTSPDGTR-CIDVRPGYCYTALTNGRCSNQLPQSITKMQC-----------CCDAGRCW 366
+ C D+ ++ +G+C N+ P S + C C D C
Sbjct: 691 YRLKASRPPVCEDIDECRDPSSCPDGKCENK-PGSFKCIACQPGYRSQGGGACRDVNEC- 748
Query: 367 SPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLG-PIPPVLPVPPGFPPGPQI 425
+ G +P C F C+ Y P P G V G I
Sbjct: 749 AEGSPCSPGWCE-NLPGSFRCTCA--------QGYAPAPDGRSCLDVDECEAGDVCDNGI 799
Query: 426 PVPRPP------VEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKG 479
P + + SR+ ++ D+ C G CI T GS RC C +G
Sbjct: 800 CSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAA----CIGGDCINTNGSYRCLCPQG 855
Query: 480 FQLDLRGECIDVDECEKNPCA---GGECINNQGSYTCQCRAGYQSTLTRTECRDID---- 532
+L +C D+DEC ++P G C N QGSY C C G+ T + C +++
Sbjct: 856 HRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHH 915
Query: 533 --ECLQN----------------------------GRICNNGRC-INTDGSFHCVCNAGF 561
EC N G C C + + FH +C G
Sbjct: 916 KKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGK 975
Query: 562 HVTRDGKNCE-------DMDECSI--RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK 612
T+D D+DEC + +C G C+N ++C CK GF + C
Sbjct: 976 GYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECV 1035
Query: 613 DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTH-------MRSTCYGGY 665
D++EC C NG C NT G YRC C P R C+ R C+
Sbjct: 1036 DVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQR 1095
Query: 666 -KRGQCIKPLFG-AVTKSECCCASTEYAFGEPCQPCPAQNSAEY---------------- 707
+ G C PL G A+T +CCC +G C+PCP + + +
Sbjct: 1096 GEDGMCAGPLAGPALTFDDCCCRQGR-GWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSP 1154
Query: 708 ------------------QALCSSGPGMTSAGSDINEC------------ALDPD----- 732
+ C SG + G + EC +D D
Sbjct: 1155 LLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECREL 1214
Query: 733 -----ICPNGICENLRGTYKCICNSGYEVDSTGKNCV 764
+C + C N G+++C+C +G+ CV
Sbjct: 1215 NQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACV 1251
Score = 125 bits (313), Expect = 8e-28
Identities = 68/187 (36%), Positives = 97/187 (51%), Gaps = 25/187 (13%)
Query: 851 GTCWQTVIDGR-CEIN-INGATLKSQCCSSLGAAWG-SPCTLC----------------Q 891
G C+Q + + C N + G T + CC S+G AWG S C C +
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGE 336
Query: 892 VDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICL 951
V C +GY R+ T C+DI+EC + PGVC++G C+N GS++C CP G +L + C+
Sbjct: 337 VGADCPQGYKRLNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 395
Query: 952 DIRLE---TCF-LRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEEL 1007
+ E CF L + +C P+ R CCCSVG AWG C+ CP T ++E+
Sbjct: 396 ADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGA-RCQRCPTDGTAAFKEI 454
Query: 1008 CPRGPGF 1014
CP G G+
Sbjct: 455 CPAGKGY 461
Score = 109 bits (272), Expect = 4e-23
Identities = 66/189 (34%), Positives = 84/189 (44%), Gaps = 10/189 (5%)
Query: 2520 TSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQH 2579
T + +EC + N+CG G C P ++C C G+ C DV+ECE C
Sbjct: 570 TQVTETDECRLNQNICGH-GECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-CGP 627
Query: 2580 G---CQNIIGGYRCSCPQGYLQHYQ--WNQCVDENECLSAHICG-GASCHNTLGSYKCMC 2633
G C N G Y C C +GY H CVD NEC H+CG G C N G YKC C
Sbjct: 628 GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNC 687
Query: 2634 PAGFQYEQFSGG-CQDINECGSAQAPCSYGCSNTEGGYLC-GCPPGYFRIGQGHCVSGMG 2691
G++ + C+DI+EC + C N G + C C PGY G G C
Sbjct: 688 YPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 747
Query: 2692 MGRGNPEPP 2700
G+P P
Sbjct: 748 CAEGSPCSP 756
Score = 86.7 bits (213), Expect = 3e-16
Identities = 65/228 (28%), Positives = 97/228 (42%), Gaps = 60/228 (26%)
Query: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWG-TPCEMCPAVNTS------- 1583
G C+ D P+ G SN + + CC S+G AWG + C CP + +
Sbjct: 277 GRCFQDTLPKQPCG----SNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGP 332
Query: 1584 ---EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLN 1640
E CP G R N + +DI+EC +PG+C+ G C+N GS++C CP G+ L
Sbjct: 333 VRGEVGADCPQGYK-RLN--STHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSL- 387
Query: 1641 EDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYY 1700
GP C D + +SLC+R
Sbjct: 388 ------------------GPSRTQ---------CIADKPE----------EKSLCFRLVS 410
Query: 1701 ADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLC 1748
++Q C L +T+++CCCS +G+AW C++CP T F +C
Sbjct: 411 PEHQ-CQHPLTTRLTRQLCCCS--VGKAWGARCQRCPTDGTAAFKEIC 455
Score = 64.7 bits (156), Expect = 1e-09
Identities = 51/162 (31%), Positives = 71/162 (43%), Gaps = 23/162 (14%)
Query: 1042 GKC-RNTIGSFKCRCDSGFALDSEERNCTDI------DECRISPDLCGRGQCVNTP--GD 1092
G+C ++T+ C + L +E C I +C P L G P G+
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGE 336
Query: 1093 FECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISA 1152
C +GY+ + +C DI+EC P +CR G C N GSYRC CPPGH L P+ +
Sbjct: 337 VGADCPQGYKR--LNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 1153 CIDINECELSAHLC-----PNGRC----VNLIGKYQCACNPG 1185
CI E S LC P +C + + C C+ G
Sbjct: 394 CIADKPEEKS--LCFRLVSPEHQCQHPLTTRLTRQLCCCSVG 433
Score = 63.5 bits (153), Expect = 3e-09
Identities = 39/127 (30%), Positives = 53/127 (41%), Gaps = 17/127 (13%)
Query: 2070 CSSPKSRNHSKQECCCALKGEGWGDP-CELCPT-------EPDEAFRQI---CPYGSGII 2118
C S +KQE CC G WG C CP +P ++ CP G +
Sbjct: 289 CGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRL 348
Query: 2119 VGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGN 2178
D++EC P VC+HG C+N GSYRC CP G+ L + +C P
Sbjct: 349 --NSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSR----TQCIADKPEEK 402
Query: 2179 GTCKNVI 2185
C ++
Sbjct: 403 SLCFRLV 409
Score = 61.2 bits (147), Expect = 1e-08
Identities = 41/121 (33%), Positives = 57/121 (47%), Gaps = 16/121 (13%)
Query: 2337 GYCFTEVLQNMCQIGSSNRNPVTKSECCCDG-GRGWGPH-CEICPFQGTVAFKKL----- 2389
G CF + L GS+ +TK E CC G WG C CP +K
Sbjct: 277 GRCFQDTLPKQ-PCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRG 335
Query: 2390 -----CPHG--RGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC 2442
CP G R T+ DI+EC + VCR+G+C+N+ GSY C+C G++ + T C
Sbjct: 336 EVGADCPQGYKRLNSTHCQDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Query: 2443 V 2443
+
Sbjct: 395 I 395
Score = 58.9 bits (141), Expect = 7e-08
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 1829 GSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTM 1888
G DC GY+ ++ C D NEC +P +C HG C++ GS+ C+C G +T
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 1889 CLDINECERDAC 1900
C+ E+ C
Sbjct: 394 CIADKPEEKSLC 405
Score = 55.1 bits (131), Expect = 1e-06
Identities = 45/146 (30%), Positives = 60/146 (41%), Gaps = 40/146 (27%)
Query: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKP-CEQCPIPSTDEFATLCGSQRPGFVIDIYTG 1762
Q C L +TK+ CC +IG AW + C +CP G Q+PG
Sbjct: 287 QPCGSNPLPGLTKQEDCCG-SIGTAWGQSKCHKCPQ------LQYTGVQKPG-------- 331
Query: 1763 LPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNA 1822
PV G +CP G+ + C+DI+EC VC R+
Sbjct: 332 -PVR--------------------GEVGADCPQGYKRLNSTH-CQDINECAMPGVC-RHG 368
Query: 1823 ECINTAGSYRCDCKPGYRF-TSTGQC 1847
+C+N GSYRC C PG+ S QC
Sbjct: 369 DCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 48.1 bits (113), Expect = 1e-04
Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 13/83 (15%)
Query: 2565 CEDVDECEGNHRCQHGCQN-----------IIGGYRCSCPQGYLQHYQWNQCVDENECLS 2613
C + G +C H C + G CPQGY + C D NEC
Sbjct: 304 CGSIGTAWGQSKC-HKCPQLQYTGVQKPGPVRGEVGADCPQGY-KRLNSTHCQDINECAM 361
Query: 2614 AHICGGASCHNTLGSYKCMCPAG 2636
+C C N GSY+C+CP G
Sbjct: 362 PGVCRHGDCLNNPGSYRCVCPPG 384
Score = 39.3 bits (90), Expect = 0.057
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 19/75 (25%)
Query: 119 CNIRCMNGGSCSDDHCLCQKGYIGTHCGQP---------------VCESGCLNGGRCVAP 163
C C+ G C D CQ+G T G+ VC C+NGG+C +
Sbjct: 71 CKRTCLKG-QCRDS---CQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSR 126
Query: 164 NRCACTYGFTGPQCE 178
N+C C FTG C+
Sbjct: 127 NQCLCPPDFTGRFCQ 141
Score = 38.9 bits (89), Expect = 0.074
Identities = 35/118 (29%), Positives = 43/118 (36%), Gaps = 11/118 (9%)
Query: 42 AKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCT 101
A RG GG AL R+ P + C+ CR SC G
Sbjct: 46 AGERGAGGGGAL-----ARERFKVVFAP----VICKRTCLKGQCRDSCQQGSNMTLIGEN 96
Query: 102 CPSGQIAPSCGSRSIQHCNIRCMNGGSCSD-DHCLCQKGYIGTHCGQPVCESGCLNGG 158
S G R + C + CMNGG CS + CLC + G C P +G GG
Sbjct: 97 GHSTDTLTGSGFRVVV-CPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGG 153
Score = 37.0 bits (84), Expect = 0.28
Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 2/48 (4%)
Query: 1876 CHTGFKTNDDQTMCLDINECERDA-CGNGTCRNTIGSFNCRCNHGFIL 1922
C G+K + T C DINEC C +G C N GS+ C C G L
Sbjct: 341 CPQGYKRLNS-THCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSL 387
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 419 bits (1077), Expect = e-116
Identities = 311/1064 (29%), Positives = 434/1064 (40%), Gaps = 245/1064 (23%)
Query: 970 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 1029
P+ G + + CC S+G AWG +C +CP +Y + GP
Sbjct: 293 PLPGLTKQEDCCGSIGTAWGQSKCHKCPQL---QYTGVQKPGP----------------- 332
Query: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
R +G+ C G+ +C DI+EC + P +C G C+N
Sbjct: 333 --------------VRGEVGA---DCPQGYKR-LNSTHCQDINECAM-PGVCRHGDCLNN 373
Query: 1090 PGDFECKCDEGYESGFMMMKNCMDIDE--------------CQRDPLLCR---------- 1125
PG + C C G+ G + D E CQ PL R
Sbjct: 374 PGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQH-PLTTRLTRQLCCCSV 432
Query: 1126 ----GGVCHN--TEGS--YRCECPPG---HQLSPNISACIDINECELSAHLCPNGRCV-N 1173
G C T+G+ ++ CP G H L+ + + I E + S L P+G
Sbjct: 433 GKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSHQTLTIQ-GESDFSLFLHPDGPPKPQ 491
Query: 1174 LIGKYQCACNPGYHSTPDRLFCVDI---DECSIMNGGCETFCTNSEGSYECSCQPGFALM 1230
+ + P + +R D +E S+ T + E +P M
Sbjct: 492 QLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTM 551
Query: 1231 -------PDQRSCTDI--------DECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 1275
P RS +I DEC N NIC G+C P +Y C C G+ +
Sbjct: 552 RWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQH 611
Query: 1276 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTG--CTDINECEIGAHNC 1333
+ CVDVNEC+ P G C NT GS+ CHC+ GY G G C D+NEC H C
Sbjct: 612 RYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLC 670
Query: 1334 GKHAVCTNTAGSFKCSCSPGWIGDGIK---CTDLDECSNGTHMCSQHADCKNTMGSYRCL 1390
G C N G +KC+C PG+ + C D+DEC + + C+N GS++C+
Sbjct: 671 GDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSC--PDGKCENKPGSFKCI 728
Query: 1391 -CKEGYTGDGF-TCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDID 1448
C+ GY G C D++EC+E + C G C N PG +RC C G+ P+ DG++C D+D
Sbjct: 729 ACQPGYRSQGGGACRDVNECAEG-SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVD 787
Query: 1449 ECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGS 1508
EC ++C G C N PG F+C+C GY L R +C D++EC P CI G+C+NT GS
Sbjct: 788 ECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGS 847
Query: 1509 YICDCPPDFEL----------------------------------------NPT--RVGC 1526
Y C CP L PT + GC
Sbjct: 848 YRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGC 907
Query: 1527 VDTRSGN----CYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEM--CPAV 1580
+ + CYL+ + C + + V++ CCCSLG WG CE+ CP
Sbjct: 908 EEVEQPHHKKECYLNF-----DDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVY 962
Query: 1581 NTSEYKILCPGGEGFRPNPITV-----ILEDIDECQELPG-LCQGGKCINTFGSFQCRCP 1634
+++E+ LCP G+G+ + V DIDEC +C+ GKC+NT ++C C
Sbjct: 963 SSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCK 1022
Query: 1635 TGYYLN-----------------------EDTR-----VCD------------------D 1648
G+Y + E+TR C D
Sbjct: 1023 QGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMD 1082
Query: 1649 VNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM---------DMRRSLCYRNY 1699
V+EC+ P C PG C N G+Y C C P ++ G +C RR +C+
Sbjct: 1083 VDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQR 1142
Query: 1700 YADNQTCDGELLF-NMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGF--V 1756
D C G L +T CCC GR W C CP S+ F
Sbjct: 1143 GEDGM-CAGPLAGPALTFDDCCCRQ--GRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDT 1199
Query: 1757 IDIYTGLP--------VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCED 1808
+ G P D DECR C +G C+ G CECP GF + C D
Sbjct: 1200 SPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVD 1254
Query: 1809 IDEC----QNGPVCQRNAECINTAGSYRCDCKPGY-RFTSTGQC 1847
IDEC Q G +C ++ C+NT+GS+RC CK G+ R G C
Sbjct: 1255 IDECRELNQRGLLC-KSERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 402 bits (1032), Expect = e-111
Identities = 311/1076 (28%), Positives = 431/1076 (40%), Gaps = 222/1076 (20%)
Query: 184 GPCFT-VISNQMCQGQLSGIVCTKTLCCATVGRAWGHP-CEMCPAQPHPCRRGFIPNIRT 241
G CF + Q C + + CC ++G AWG C CP + T
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQY-----------T 325
Query: 242 GACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHK-LNEVSQKCEDIDECSTIPGICE 300
G + PG +G VG+ CP G+K LN S C+DI+EC+ +PG+C
Sbjct: 326 GVQK--------PGPVRG-----EVGA---DCPQGYKRLN--STHCQDINECA-MPGVCR 366
Query: 301 GGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP---GYCYTALT-NGRCSNQLPQSITKM 356
G+C N SY C CPPG P T+CI +P C+ ++ +C + L +T+
Sbjct: 367 HGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQ 426
Query: 357 QCCCDAGRCW--------SPGVTVAPEMCP---------------IRATEDFNKLC---- 389
CCC G+ W + G E+CP I+ DF+
Sbjct: 427 LCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDG 486
Query: 390 -SVPMVIPGRPEYPPPPL-----------GPIP---------PVLPVPPGFPPGPQIPVP 428
P +P P PPP P+ P P P I P
Sbjct: 487 PPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRP 546
Query: 429 RPP-----VEYLYPSREPPRVLPVNV--TDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQ 481
PP + L PSR + P V TD C+L + +C +G C+P P C CN G++
Sbjct: 547 SPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYR 606
Query: 482 LDLRGE-CIDVDECEKNPCAGGE--CINNQGSYTCQCRAGYQSTLTR--TECRDIDECLQ 536
+ C+DV+ECE PC G C+N GSY C C GY+ + C D++EC +
Sbjct: 607 SHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK 666
Query: 537 NGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN-CEDMDECSIRNMCLNGMCINEDGSFK 595
+ G CIN G + C C G+ + CED+DEC + C +G C N+ GSFK
Sbjct: 667 PHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFK 726
Query: 596 CI-CKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
CI C+PG++ + G C+D+NEC C G C N GS+RC C G A DGR C+D
Sbjct: 727 CIACQPGYR-SQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 785
Query: 655 THMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG 714
C G C + S C + Y C + ++ A C G
Sbjct: 786 V---DECEAG---DVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGG 839
Query: 715 PGMTSAGS------------------DINECALDPDIC-PNGICENLRGTYKCICNSGYE 755
+ + GS DI+EC+ DP +C P+G C+NL+G+Y C+C+ G+
Sbjct: 840 DCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 899
Query: 756 VDSTGKNCVDI------NECVLN---SLLCDNGQCRN----------------------- 783
C ++ EC LN ++ CD+ N
Sbjct: 900 PTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPC 959
Query: 784 ---TPGSFVCTCPKGFIYKPD-------LKTCEDIDEC---ESSPCINGVCKNSPGSFIC 830
+ F CP G Y D + DIDEC S C G C N+ + C
Sbjct: 960 PVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYEC 1019
Query: 831 ECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLC 890
C D C++ + +G CE G C+ A SP
Sbjct: 1020 YCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYR-----CACTPPAEYSPAQRQ 1074
Query: 891 QVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRIC 950
+ P + D+DEC+ P C+ G CVN GS++C+C +GR C
Sbjct: 1075 CLSP------------EEMDVDECQ-DPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC 1121
Query: 951 ---------LDIRLETCF-LRYEDEECTLPIAG-RHRMDACCCSVGAAWGTEECEECPMR 999
R + C+ R ED C P+AG D CCC G WG +C CP R
Sbjct: 1122 QLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGA-QCRPCPPR 1180
Query: 1000 NTPEYEELCPRGPG-----FATKEITNGKP------FFKDINECKMIPSLCTHGKCRNTI 1048
+ CP + T + GKP +D +EC+ C G+C
Sbjct: 1181 GAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRP 1232
Query: 1049 GSFKCRCDSGFALDSEERNCTDIDECRISPD---LCGRGQCVNTPGDFECKCDEGY 1101
G C C GF LD+ C DIDECR LC +CVNT G F C C G+
Sbjct: 1233 GGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGF 1288
Score = 400 bits (1028), Expect = e-110
Identities = 235/747 (31%), Positives = 336/747 (44%), Gaps = 100/747 (13%)
Query: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
+ +EC++ ++C HG+C + C C+ G+ + R C D++EC P GRG C+
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 1088 NTPGDFECKCDEGYESGF-MMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQL 1146
NT G + C C+ GY ++C+D++EC + L GG C N G Y+C C PG++L
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 693
Query: 1147 -SPNISACIDINECELSAHLCPNGRCVNLIGKYQC-ACNPGYHSTPDRLFCVDIDECSIM 1204
+ C DI+EC CP+G+C N G ++C AC PGY S C D++EC+
Sbjct: 694 KASRPPVCEDIDECR-DPSSCPDGKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECAEG 751
Query: 1205 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264
+ +C N GS+ C+C G+A PD RSC D+DECE ++CD G C+N PG ++C
Sbjct: 752 SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDNGICSNTPGSFQCQ 810
Query: 1265 CYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDIN 1324
C G+ S D C D++ECD P C+ G C NT GS+ C C G+ G+ C DI+
Sbjct: 811 CLSGYHLSRDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVGGRK-CQDID 868
Query: 1325 ECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCTDLDE---------------- 1366
EC C H C N GS+ C C G+ D C ++++
Sbjct: 869 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVF 928
Query: 1367 CSN--GTHMCSQHADCKNTMG----------------SYRCLCKE--GYTGDGFTCT--- 1403
C + T++ Q C G + LC + GYT D
Sbjct: 929 CDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGI 988
Query: 1404 ----DLDECS-ENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVF 1458
D+DEC +C G+C+N GY C C GF + C D+DEC + C
Sbjct: 989 PAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRN 1048
Query: 1459 GTCHNLPGLFRCECEIGYELDRSGGNC-----TDVNECLDPTTCISGNCVNTPGSYICDC 1513
G C N G +RC C E + C DV+EC DP C G CVN PGSY C+C
Sbjct: 1049 GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCEC 1108
Query: 1514 PPDFELNPTRVGC---------VDTRSGNCYLDIRPRGDNGDTACSNEI-GVGVSKASCC 1563
P + P+ C R C+ RG++G C+ + G ++ CC
Sbjct: 1109 RPPWVPGPSGRDCQLPESPAERAPERRDVCW---SQRGEDG--MCAGPLAGPALTFDDCC 1163
Query: 1564 CSLGKAWGTPCEMCPAVNTSEYKILCPGGE--------------GFRPNPITVILEDIDE 1609
C G+ WG C CP + CP + G P ED DE
Sbjct: 1164 CRQGRGWGAQCRPCPPRGAGSH---CPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDE 1220
Query: 1610 CQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG----ICGPGTCYN 1665
C+ C G+C+ G C CP G+ L+ C D++EC +C C N
Sbjct: 1221 CR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVN 1275
Query: 1666 TVGNYTCICPPDYMQVNGGNNCMDMRR 1692
T G++ C+C + + C+ RR
Sbjct: 1276 TSGSFRCVCKAGFARSRPHGACVPQRR 1302
Score = 365 bits (938), Expect = e-100
Identities = 258/833 (30%), Positives = 353/833 (42%), Gaps = 193/833 (23%)
Query: 572 DMDECSI-RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGR--C 628
+ DEC + +N+C +G C+ + C C PG++ RYC D+NECE C GR C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-CGPGRGIC 632
Query: 629 VNTDGSYRCECFPG--LAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCA 686
+NT GSY C C G L VG GR CVD + +C KP C
Sbjct: 633 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLN------------ECAKPHL---------CG 671
Query: 687 STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAG----SDINECALDPDICPNGICENL 742
+ P Y+ C G + ++ DI+EC DP CP+G CEN
Sbjct: 672 DGGFCINFP---------GHYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPDGKCENK 721
Query: 743 RGTYKCI-CNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPD 801
G++KCI C GY G C D+NEC S C G C N PGSF CTC +G+ PD
Sbjct: 722 PGSFKCIACQPGYRSQGGGA-CRDVNECAEGSP-CSPGWCENLPGSFRCTCAQGYAPAPD 779
Query: 802 LKTCEDIDECESSP-CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDG 860
++C D+DECE+ C NG+C N+PGSF C+C S L ++ C + + I G
Sbjct: 780 GRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGG 839
Query: 861 RCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGV 920
C IN NG+ +C +C +G+ + G +C+DIDEC P +
Sbjct: 840 DC-INTNGSY---RC-------------------LCPQGHRLVGGRKCQDIDECSQDPSL 876
Query: 921 C-KNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRL----ETCFLRYEDEE-CTLPIAGR 974
C +G C N +GS+ C C G T C ++ + C+L ++D C +A
Sbjct: 877 CLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATN 936
Query: 975 HRMDACCCSVGAAWGTEECE--ECPMRNTPEYEELCPRGPGFATKE--ITNGKPFFKDIN 1030
CCCS+GA WG + CE CP+ ++ E+ LCP G G+ + G P +DI
Sbjct: 937 VTQQECCCSLGAGWG-DHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDI- 994
Query: 1031 ECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRI-SPDLCGRGQCVNT 1089
DEC + ++C G+CVNT
Sbjct: 995 -----------------------------------------DECMLFGSEICKEGKCVNT 1013
Query: 1090 PGDFECKCDEG-YESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSP 1148
+EC C +G Y G ++ C+D+DEC D CR GVC NT G YRC C P + SP
Sbjct: 1014 QPGYECYCKQGFYYDGNLL--ECVDVDECL-DESNCRNGVCENTRGGYRCACTPPAEYSP 1070
Query: 1149 NISACI-----DINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFC-------- 1195
C+ D++EC+ A C GRCVNL G Y+C C P + P C
Sbjct: 1071 AQRQCLSPEEMDVDECQDPA-ACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAE 1129
Query: 1196 ---------------------------VDIDECSIMNG-------------GCETFCTNS 1215
+ D+C G G + C S
Sbjct: 1130 RAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTS 1189
Query: 1216 EGSYECSCQPGFALM-----PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFM 1270
+ L+ + S D DEC C G+C PG C C GF
Sbjct: 1190 QSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGFQ 1244
Query: 1271 ASEDMKTCVDVNEC-DLNPN--ICLSGTCENTKGSFICHCDMGYSGKKGKTGC 1320
CVD++EC +LN +C S C NT GSF C C G++ + C
Sbjct: 1245 LDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 358 bits (918), Expect = 6e-98
Identities = 252/789 (31%), Positives = 353/789 (44%), Gaps = 114/789 (14%)
Query: 1318 TGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIK--CTDLDECSNGTHMCS 1375
T T+ +EC + + CG H C + C C+PG+ C D++EC C
Sbjct: 570 TQVTETDECRLNQNICG-HGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE--AEPCG 626
Query: 1376 Q-HADCKNTMGSYRCLCKEGYT----GDGFTCTDLDECSENLNLCGNGQ-CLNAPGGYRC 1429
C NT GSY C C GY G +C DL+EC++ +LCG+G C+N PG Y+C
Sbjct: 627 PGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKP-HLCGDGGFCINFPGHYKC 685
Query: 1430 ECDMGF-VPSADGKACEDIDECSLPNICVFGTCHNLPGLFRC-ECEIGYELDRSGGNCTD 1487
C G+ + ++ CEDIDEC P+ C G C N PG F+C C+ GY + GG C D
Sbjct: 686 NCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR-SQGGGACRD 744
Query: 1488 VNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDT 1547
VNEC + + C G C N PGS+ C C + P C+D +D GD D
Sbjct: 745 VNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD-------VDECEAGDVCDN 797
Query: 1548 A-CSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILED 1606
CSN G C+ + S + C ED
Sbjct: 798 GICSNTPG----------------SFQCQCLSGYHLSRDRSHC---------------ED 826
Query: 1607 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC-ETPGICGP-GTCY 1664
IDEC + P C GG CINT GS++C CP G+ L R C D++EC + P +C P G C
Sbjct: 827 IDEC-DFPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACK 884
Query: 1665 NTVGNYTCICPPDYMQVNGGNNCMDMR----RSLCYRNYYADNQTCDGELLFNMTKKMCC 1720
N G+Y C+C + + C ++ + CY N+ D CD L N+T++ CC
Sbjct: 885 NLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNF-DDTVFCDSVLATNVTQQECC 943
Query: 1721 CSYNIGRAWNKPCE--QCPIPSTDEFATLCGSQRPGFVID---IYTGLPV--DIDECREI 1773
CS +G W CE CP+ S+ EF +LC + G+ D + G+P DIDEC
Sbjct: 944 CS--LGAGWGDHCEIYPCPVYSSAEFHSLCPDGK-GYTQDNNIVNYGIPAHRDIDECMLF 1000
Query: 1774 PG-VCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYR 1832
+C+ G C+N + C C GF+Y+ LL C D+DEC + C RN C NT G YR
Sbjct: 1001 GSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNC-RNGVCENTRGGYR 1059
Query: 1833 CDCKPGYRFT-STGQC-----NDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQ 1886
C C P ++ + QC D +ECQ+ P C G+C++ GS+ C C +
Sbjct: 1060 CACTPPAEYSPAQRQCLSPEEMDVDECQD-PAACRPGRCVNLPGSYRCECRPPWVPGPSG 1118
Query: 1887 TMC-LDINECERDACGNGTCRNTIGSFNCRCN--HGFILSHNNDCIDVDECASGNGNLCR 1943
C L + ER C + G G L+ ++ C C G G +
Sbjct: 1119 RDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCC-----CRQGRGWGAQ 1173
Query: 1944 NGQCINTVGSFQC-----QCNEGYEVAP---------DGRTCVDINECLLEPRKCAPGTC 1989
C C + N ++ +P + + D +EC +C G C
Sbjct: 1174 CRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDEC-----RCVSGRC 1228
Query: 1990 QNLDGSYRCICPPGYSLQNEKCEDID--ECVEEPE---ICALGTCSNTEGSFKCLCPEGF 2044
G C CP G+ L + +D EC E + +C C NT GSF+C+C GF
Sbjct: 1229 VPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGF 1288
Query: 2045 SLSSSGRRC 2053
+ S C
Sbjct: 1289 ARSRPHGAC 1297
Score = 356 bits (913), Expect = 2e-97
Identities = 227/690 (32%), Positives = 313/690 (45%), Gaps = 131/690 (18%)
Query: 1766 DIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECI 1825
+ DECR +C +G C+ + C C G+ + + C D++EC+ P C+
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 1826 NTAGS--------------------------------------------YRCDCKPGYRF 1841
NT GS Y+C+C PGYR
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRL 693
Query: 1842 TSTGQ--CNDRNECQEIPNICSHGQCIDTVGSFYCL-CHTGFKTNDDQTMCLDINEC-ER 1897
++ C D +EC++ P+ C G+C + GSF C+ C G+++ C D+NEC E
Sbjct: 694 KASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYRSQGGGA-CRDVNECAEG 751
Query: 1898 DACGNGTCRNTIGSFNCRCNHGFI-LSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQC 1956
C G C N GSF C C G+ C+DVDEC + G++C NG C NT GSFQC
Sbjct: 752 SPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA--GDVCDNGICSNTPGSFQC 809
Query: 1957 QCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL-QNEKCEDID 2015
QC GY ++ D C DI+EC P C G C N +GSYRC+CP G+ L KC+DID
Sbjct: 810 QCLSGYHLSRDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDID 868
Query: 2016 ECVEEPEIC-ALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSY----CYAKFEGGK- 2069
EC ++P +C G C N +GS+ C+C EGF+ + C+++ + CY F+
Sbjct: 869 ECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVF 928
Query: 2070 CSSPKSRNHSKQECCCALKGEGWGDPCEL--CPTEPDEAFRQICPYGSGIIVGPDDSAV- 2126
C S + N ++QECCC+L G GWGD CE+ CP F +CP G G D++ V
Sbjct: 929 CDSVLATNVTQQECCCSL-GAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYT--QDNNIVN 985
Query: 2127 -------DMDECK--EPDVCKHGQCINTDGSYRCECPFGYILAGN--ECVDTDECSVGNP 2175
D+DEC ++CK G+C+NT Y C C G+ GN ECVD DEC +
Sbjct: 986 YGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN 1045
Query: 2176 CGNGTCKNVIGGFECTCEEGFEPGP-MMTC-----EDINECAQNPLLC-AFRCVNTYGSY 2228
C NG C+N GG+ C C E P C D++EC Q+P C RCVN GSY
Sbjct: 1046 CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDEC-QDPAACRPGRCVNLPGSY 1104
Query: 2229 ECKCPVGYVLREDRRMCK----DEDECEEGKHDCTEKQMECKNLIGTYM--------CIC 2276
C+C +V R C+ + E + C ++ E G C C
Sbjct: 1105 RCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCC 1164
Query: 2277 ----GPGYQRRP-----DGEGC------------------------VDENECQTKPGICE 2303
G G Q RP G C D +E + C
Sbjct: 1165 RQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCV 1224
Query: 2304 NGRCLNTRGSYTCECNDGFTASPNQDECLD 2333
+GRC+ G CEC GF ++ C+D
Sbjct: 1225 SGRCVPRPGGAVCECPGGFQLDASRARCVD 1254
Score = 349 bits (896), Expect = 2e-95
Identities = 241/771 (31%), Positives = 324/771 (42%), Gaps = 126/771 (16%)
Query: 1963 EVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL--QNEKCEDIDECVEE 2020
E+AP T D EC L C G C Y C C PGY Q+ C D++EC E
Sbjct: 566 EIAPTQVTETD--ECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAE 623
Query: 2021 PEICALGTCSNTEGSFKCLCPEGFSL--SSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNH 2078
P G C NT GS+ C C G+ L + GR C DL +C+ P
Sbjct: 624 PCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLN-----------ECAKPH---- 668
Query: 2079 SKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCK 2138
L G+G C P ++ C G + D+DEC++P C
Sbjct: 669 --------LCGDGG-----FCINFPGH-YKCNCYPGYRLKASRPPVCEDIDECRDPSSCP 714
Query: 2139 HGQCINTDGSYRC-ECPFGY-ILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGF 2196
G+C N GS++C C GY G C D +EC+ G+PC G C+N+ G F CTC +G+
Sbjct: 715 DGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGY 774
Query: 2197 EPGPM-MTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGK 2255
P P +C D++EC + C NT GS++C+C GY L DR C+D DEC+
Sbjct: 775 APAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD--- 831
Query: 2256 HDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC-ENGRCLNTRGSY 2314
+C N G+Y C+C G+ R G C D +EC P +C +G C N +GSY
Sbjct: 832 FPAACIGGDCINTNGSYRCLCPQGH-RLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSY 890
Query: 2315 TCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQI---GSSNRNPVTKSECCCDGGRGW 2371
C C++GFT + +Q C + + + E N S VT+ ECCC G GW
Sbjct: 891 VCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW 950
Query: 2372 GPHCEI--CPFQGTVAFKKLCPHGRGFMTNG----------ADIDECKVI-HDVCRNGEC 2418
G HCEI CP + F LCP G+G+ + DIDEC + ++C+ G+C
Sbjct: 951 GDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKC 1010
Query: 2419 VNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQE 2478
VN + Y C CK G+ D CVD++EC N +C+NT G Y+C+C
Sbjct: 1011 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSP 1070
Query: 2479 DGRSC-----KDLDECATKQHNCQFLCVNTIGGFT---------------CKCP------ 2512
R C D+DEC CVN G + C+ P
Sbjct: 1071 AQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAER 1130
Query: 2513 ------------------------PGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSF 2548
P T C + C +G + P S
Sbjct: 1131 APERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQ 1190
Query: 2549 --------TCECQRGFSLDQTGSSCEDVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQH 2599
T G SS ED DEC RC G C GG C CP G+
Sbjct: 1191 SESNSFWDTSPLLLGKPPRDEDSSEEDSDEC----RCVSGRCVPRPGGAVCECPGGFQLD 1246
Query: 2600 YQWNQCVDENECLSAH----ICGGASCHNTLGSYKCMCPAGFQYEQFSGGC 2646
+CVD +EC + +C C NT GS++C+C AGF + G C
Sbjct: 1247 ASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 349 bits (896), Expect = 2e-95
Identities = 249/775 (32%), Positives = 334/775 (43%), Gaps = 134/775 (17%)
Query: 288 DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVR--------PGYCYTA 339
+ DEC IC GEC Y C C PG+ + P C+DV PG
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPG----- 628
Query: 340 LTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRP 399
G C N + C C+ G G R+ D N+ C+ P +
Sbjct: 629 --RGICMN----TGGSYNCHCNRGYRLHVGAGG-------RSCVDLNE-CAKPHLC---- 670
Query: 400 EYPPPPLGPIPPVLPVPPGFP----PGPQIPVPRPPV-EYLYPSREPPRVLPVNVTDYCQ 454
G + P + PG ++ RPPV E + R+P
Sbjct: 671 -------GDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS----------- 712
Query: 455 LVRYLCQNGRCIPTPGSCRC-ECNKGFQLDLRGECIDVDEC-EKNPCAGGECINNQGSYT 512
C +G+C PGS +C C G++ G C DV+EC E +PC+ G C N GS+
Sbjct: 713 -----CPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFR 767
Query: 513 CQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCED 572
C C GY C D+DEC + G +C+NG C NT GSF C C +G+H++RD +CED
Sbjct: 768 CTCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCED 826
Query: 573 MDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICM-NGRCVN 630
+DEC C+ G CIN +GS++C+C G +L GR C+DI+EC + P +C+ +G C N
Sbjct: 827 IDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGACKN 885
Query: 631 TDGSYRCECFPGLAVGLDGRVCVDT---HMRSTCYGGYKRGQ-CIKPLFGAVTKSECCCA 686
GSY C C G D C + H + CY + C L VT+ ECCC
Sbjct: 886 LQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCC- 944
Query: 687 STEYAFGEPCQ--PCPAQNSAEYQALCSSGPGMTS----------AGSDINECAL-DPDI 733
S +G+ C+ PCP +SAE+ +LC G G T A DI+EC L +I
Sbjct: 945 SLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEI 1004
Query: 734 CPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCP 793
C G C N + Y+C C G+ D CVD++EC L+ C NG C NT G + C C
Sbjct: 1005 CKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACT 1063
Query: 794 KGFIYKPDLKTC-----EDIDECES-SPCINGVCKNSPGSFICECSSESTLDPTKTIC-- 845
Y P + C D+DEC+ + C G C N PGS+ CEC P+ C
Sbjct: 1064 PPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQL 1123
Query: 846 -------IETIKGTCW-QTVIDGRCEININGATLK-SQCCSSLGAAWGSPCTLC------ 890
+ CW Q DG C + G L CC G WG+ C C
Sbjct: 1124 PESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAG 1183
Query: 891 --------------QVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQ 936
P+ R + + ED DEC C +G CV G C+
Sbjct: 1184 SHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCE 1238
Query: 937 CPSGMTLDATGRICLDI----RLETCFLRYEDEECTLPIAGRHRMDACCCSVGAA 987
CP G LDA+ C+DI L L + E C + +G R C C G A
Sbjct: 1239 CPGGFQLDASRARCVDIDECRELNQRGLLCKSERC-VNTSGSFR---CVCKAGFA 1289
Score = 329 bits (843), Expect = 3e-89
Identities = 236/774 (30%), Positives = 332/774 (42%), Gaps = 183/774 (23%)
Query: 1846 QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC--GNG 1903
Q + +EC+ NIC HG+C+ + C C+ G++++ C+D+NECE + C G G
Sbjct: 571 QVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG 630
Query: 1904 TCRNTIGSFNCRCNHGFIL---SHNNDCIDVDECASGNGNLCRNGQ-CINTVGSFQCQCN 1959
C NT GS+NC CN G+ L + C+D++ECA +LC +G CIN G ++C C
Sbjct: 631 ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA--KPHLCGDGGFCINFPGHYKCNCY 688
Query: 1960 EGYEV-APDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCI-CPPGYSLQ-NEKCEDIDE 2016
GY + A C DI+EC +P C G C+N GS++CI C PGY Q C D++E
Sbjct: 689 PGYRLKASRPPVCEDIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 747
Query: 2017 CVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSR 2076
C E C+ G C N GSF+C C +G++ + GR C D+ +C +
Sbjct: 748 CAEGSP-CSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDV-----------DECEA---- 791
Query: 2077 NHSKQECCCALKGEGWGDPCE--LCPTEPDEAFRQICPYGSGIIVGPDDS-AVDMDECKE 2133
GD C+ +C P +F+ C SG + D S D+DEC
Sbjct: 792 ----------------GDVCDNGICSNTPG-SFQ--CQCLSGYHLSRDRSHCEDIDECDF 832
Query: 2134 PDVCKHGQCINTDGSYRCECPFGY-ILAGNECVDTDECSVGNP--CGNGTCKNVIGGFEC 2190
P C G CINT+GSYRC CP G+ ++ G +C D DECS +G CKN+ G + C
Sbjct: 833 PAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVC 892
Query: 2191 TCEEGFEP-GPMMTCEDI------NECAQN---PLLCAFRCVNTYGSYECKCPVG----- 2235
C+EGF P CE++ EC N + C EC C +G
Sbjct: 893 VCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGD 952
Query: 2236 ---------YVLREDRRMC--------------------KDEDE--------CEEGK--- 2255
Y E +C +D DE C+EGK
Sbjct: 953 HCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVN 1012
Query: 2256 ----HDCTEKQ--------ME-----------------CKNLIGTYMCICGPGYQRRPDG 2286
++C KQ +E C+N G Y C C P + P
Sbjct: 1013 TQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQ 1072
Query: 2287 EGC-----VDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDEC---------L 2332
C +D +ECQ P C GRC+N GSY CEC + P+ +C
Sbjct: 1073 RQCLSPEEMDVDECQ-DPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERA 1131
Query: 2333 DNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPH 2392
R C+++ ++ G +T +CCC GRGWG C CP +G + CP
Sbjct: 1132 PERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSH---CPT 1188
Query: 2393 G-------------------RGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGY 2433
R ++ D DEC+ C +G CV G C C G+
Sbjct: 1189 SQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCECPGGF 1243
Query: 2434 TPDITGTSCVDLNEC---NQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSC 2483
D + CVD++EC NQ C + C NT GS++C C G+ +C
Sbjct: 1244 QLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 322 bits (826), Expect = 3e-87
Identities = 293/1037 (28%), Positives = 398/1037 (38%), Gaps = 180/1037 (17%)
Query: 598 CKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHM 657
C G++ + +C+DINEC PG+C +G C+N GSYRC VC H
Sbjct: 341 CPQGYKRLNS-THCQDINECAMPGVCRHGDCLNNPGSYRC-------------VCPPGHS 386
Query: 658 RSTCYGGYKRGQCI--KPLFGAVTKSECC-CASTEYAFGEPCQPCPAQNSAEYQALCSSG 714
G R QCI KP KS C S E+ CQ CS G
Sbjct: 387 L-----GPSRTQCIADKP----EEKSLCFRLVSPEHQ----CQHPLTTRLTRQLCCCSVG 433
Query: 715 PGMTSAGSDINECALD-----PDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINEC 769
G+ C D +ICP G GY + ++ + E
Sbjct: 434 KAW---GARCQRCPTDGTAAFKEICPAG--------------KGYHILTSHQTLTIQGES 476
Query: 770 VLNSLLCDNG-----QCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNS 824
+ L +G Q +P P+ + + T + E S + +
Sbjct: 477 DFSLFLHPDGPPKPQQLPESPSQ--APPPEDTEEERGVTTDSPVSEERSVQQSHPTATTT 534
Query: 825 PGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWG 884
P E S + PT + + + I + L C G
Sbjct: 535 PARPYPELISRPS-PPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPG 593
Query: 885 SPCTLCQVDPICGKGY-SRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTL 943
P C C GY S + C D++ECE P G+C+NT GS+ C C G L
Sbjct: 594 PPDYSCH----CNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRL 649
Query: 944 D--ATGRICLDIRLETCFLRY--EDEECTLPIAGRHRMDACCCSVG---------AAWGT 990
A GR C+D L C + D + G ++ C C G
Sbjct: 650 HVGAGGRSCVD--LNECAKPHLCGDGGFCINFPGHYK---CNCYPGYRLKASRPPVCEDI 704
Query: 991 EECEE---CP---MRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKC 1044
+EC + CP N P + PG+ ++ G +D+NEC S C+ G C
Sbjct: 705 DECRDPSSCPDGKCENKPGSFKCIACQPGYRSQ----GGGACRDVNECAE-GSPCSPGWC 759
Query: 1045 RNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESG 1104
N GSF+C C G+A + R+C D+DEC D+C G C NTPG F+C+C GY
Sbjct: 760 ENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDNGICSNTPGSFQCQCLSGYHLS 818
Query: 1105 FMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAH 1164
+C DIDEC P C GG C NT GSYRC CP GH+L C DI+EC
Sbjct: 819 -RDRSHCEDIDECDF-PAACIGGDCINTNGSYRCLCPQGHRLVGG-RKCQDIDECSQDPS 875
Query: 1165 LC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDID------ECSIMNGG---CETFCTN 1214
LC P+G C NL G Y C C+ G+ T D+ C +++ EC + C++
Sbjct: 876 LCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLAT 935
Query: 1215 SEGSYECSCQPG--------------------FALMPDQRSCT--------------DID 1240
+ EC C G +L PD + T DID
Sbjct: 936 NVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 995
Query: 1241 ECE-DNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENT 1299
EC IC G+C N Y C C GF ++ CVDV+EC L+ + C +G CENT
Sbjct: 996 ECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENT 1054
Query: 1300 KGSFICHCDMGYSGKKGKTGCT-----DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW 1354
+G + C C + C D++EC+ A + C N GS++C C P W
Sbjct: 1055 RGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPA--ACRPGRCVNLPGSYRCECRPPW 1112
Query: 1355 IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNL 1414
+ G D + + D + +C G T D+C
Sbjct: 1113 V-PGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALT---FDDCCCRQGR 1168
Query: 1415 CGNGQCLNAP---GGYRCECD--------------MGFVPSADGKACEDIDECSLPNICV 1457
QC P G C +G P + + ED DEC CV
Sbjct: 1169 GWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR----CV 1224
Query: 1458 FGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT----CISGNCVNTPGSYICDC 1513
G C PG CEC G++LD S C D++EC + C S CVNT GS+ C C
Sbjct: 1225 SGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVC 1284
Query: 1514 PPDFELNPTRVGCVDTR 1530
F + CV R
Sbjct: 1285 KAGFARSRPHGACVPQR 1301
Score = 290 bits (742), Expect = 1e-77
Identities = 277/1051 (26%), Positives = 402/1051 (38%), Gaps = 196/1051 (18%)
Query: 1391 CKEGYTGDGFT-CTDLDECSENLNLCGNGQCLNAPGGYR--CECDMGFVPSADGKACEDI 1447
C +GY T C D++EC+ +C +G CLN PG YR C PS +
Sbjct: 341 CPQGYKRLNSTHCQDINECAMP-GVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKP 399
Query: 1448 DECSL-------PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISG 1500
+E SL + C L C C +G C C +G
Sbjct: 400 EEKSLCFRLVSPEHQCQHPLTTRLTRQLCC-CSVGKAWGARCQRCPTDGTAAFKEICPAG 458
Query: 1501 N-----------CVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTAC 1549
+ + PD P ++ +++ RG D+
Sbjct: 459 KGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPV 518
Query: 1550 SNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKI--LCPGGEGFRPNPITVILEDI 1607
S E V S + + + + P+ T + + L P P V +
Sbjct: 519 SEERSVQQSHPTATTTPARPYPELISR-PSPPTMRWFLPDLPPSRSAVEIAPTQVT--ET 575
Query: 1608 DECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT--CYN 1665
DEC+ +C G+C+ + C C GY + R C DVNECE CGPG C N
Sbjct: 576 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-CGPGRGICMN 634
Query: 1666 TVGNYTCICPPDY-MQVN-GGNNCMDMRRSLCYRNYYADNQTC-DGELLFNMT---KKMC 1719
T G+Y C C Y + V GG +C+D+ N A C DG N K C
Sbjct: 635 TGGSYNCHCNRGYRLHVGAGGRSCVDL-------NECAKPHLCGDGGFCINFPGHYKCNC 687
Query: 1720 CCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN 1779
Y + + CE DIDECR+ P C +
Sbjct: 688 YPGYRLKASRPPVCE-------------------------------DIDECRD-PSSCPD 715
Query: 1780 GVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGY 1839
G C N GSF+C + + C D++EC G C C N GS+RC C GY
Sbjct: 716 GKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGW-CENLPGSFRCTCAQGY 774
Query: 1840 RFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERD 1898
G+ C D +EC E ++C +G C +T GSF C C +G+ + D++ C DI+EC+
Sbjct: 775 APAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFP 833
Query: 1899 A-CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQ 1957
A C G C NT GS+ C C G L C D+DEC+ +G C N GS+ C
Sbjct: 834 AACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCV 893
Query: 1958 CNEGYEVAPDGRTCVDIN------ECLL------------------EPRKCAPGT----- 1988
C+EG+ D C ++ EC L + C+ G
Sbjct: 894 CDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDH 953
Query: 1989 CQNL------DGSYRCICPPG--YSLQNEKCE-------DIDECVE-EPEICALGTCSNT 2032
C+ + +CP G Y+ N DIDEC+ EIC G C NT
Sbjct: 954 CEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNT 1013
Query: 2033 EGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGW 2092
+ ++C C +GF + C D+ + G C + + C C
Sbjct: 1014 QPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGG----YRCACT------ 1063
Query: 2093 GDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCE 2152
P E P + RQ + P++ +D+DEC++P C+ G+C+N GSYRCE
Sbjct: 1064 -PPAEYSPAQ-----RQC--------LSPEE--MDVDECQDPAACRPGRCVNLPGSYRCE 1107
Query: 2153 C--PFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPM----MTCED 2206
C P+ +G +C + + P C + G E+G GP+ +T +D
Sbjct: 1108 CRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRG------EDGMCAGPLAGPALTFDD 1161
Query: 2207 INECAQNPLLCAFRCVNTYGSYECK----------CPVGYVLRED---------RRMCKD 2247
C R +G+ +C+ CP + +D
Sbjct: 1162 ----------CCCRQGRGWGA-QCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRD 1210
Query: 2248 EDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQT---KPGICEN 2304
ED EE +C C G +C C G+Q CVD +EC+ + +C++
Sbjct: 1211 EDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKS 1270
Query: 2305 GRCLNTRGSYTCECNDGFTASPNQDECLDNR 2335
RC+NT GS+ C C GF S C+ R
Sbjct: 1271 ERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1301
Score = 288 bits (737), Expect = 5e-77
Identities = 237/775 (30%), Positives = 322/775 (41%), Gaps = 144/775 (18%)
Query: 1930 DVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTC 1989
+ DEC N N+C +G+C+ + C CN GY P R CVD+NEC EP G C
Sbjct: 574 ETDECRL-NQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGIC 632
Query: 1990 QNLDGSYRCICPPGYSLQ----NEKCEDIDECVEEPEICA-LGTCSNTEGSFKCLCPEGF 2044
N GSY C C GY L C D++EC +P +C G C N G +KC C G+
Sbjct: 633 MNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGGFCINFPGHYKCNCYPGY 691
Query: 2045 SLSSSGRR-CQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGW----------- 2092
L +S C+D+ + GKC + K + C + +G
Sbjct: 692 RLKASRPPVCEDIDECRDPSSCPDGKCEN-KPGSFKCIACQPGYRSQGGGACRDVNECAE 750
Query: 2093 GDPCE--LCPTEPDEAFRQICPYGSGIIVGPDD-SAVDMDECKEPDVCKHGQCINTDGSY 2149
G PC C P +FR C G PD S +D+DEC+ DVC +G C NT GS+
Sbjct: 751 GSPCSPGWCENLPG-SFR--CTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSF 807
Query: 2150 RCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDI 2207
+C+C GY L+ + C D DEC C G C N G + C C +G C+DI
Sbjct: 808 QCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDI 867
Query: 2208 NECAQNPLLCA--FRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDC---TEKQ 2262
+EC+Q+P LC C N GSY C C G+ +D+ C +E E K +C +
Sbjct: 868 DECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGC-EEVEQPHHKKECYLNFDDT 926
Query: 2263 MECKNLIGTYM----CICGPG--------------------YQRRPDGEGCVDEN----- 2293
+ C +++ T + C C G + PDG+G +N
Sbjct: 927 VFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNY 986
Query: 2294 ---------ECQT-KPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEV 2343
EC IC+ G+C+NT+ Y C C GF N EC+D E
Sbjct: 987 GIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDE------- 1039
Query: 2344 LQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADI 2403
C S+ RN V C+ RG G C P ++ C D+
Sbjct: 1040 ----CLDESNCRNGV------CENTRG-GYRCACTPPAEYSPAQRQC-----LSPEEMDV 1083
Query: 2404 DECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC-VDLNECNQAPKPCNFICKNT 2462
DEC+ CR G CVN GSY C C+ + P +G C + + +AP+ + +C +
Sbjct: 1084 DECQ-DPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRD-VCWSQ 1141
Query: 2463 EGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIG-GFTCK-CPPGFTQHH- 2519
G EDG L A +C C G G C+ CPP H
Sbjct: 1142 RG-------------EDGMCAGPLAGPALTFDDC--CCRQGRGWGAQCRPCPPRGAGSHC 1186
Query: 2520 ------------TSCI---------DNNECTSDINLCGSKGICQNTPGSFTCECQRGFSL 2558
TS + D++E SD C S G C PG CEC GF L
Sbjct: 1187 PTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVS-GRCVPRPGGAVCECPGGFQL 1245
Query: 2559 DQTGSSCEDVDEC-EGNHR---CQ-HGCQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608
D + + C D+DEC E N R C+ C N G +RC C G+ + CV +
Sbjct: 1246 DASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQ 1300
Score = 275 bits (703), Expect = 5e-73
Identities = 229/818 (27%), Positives = 325/818 (39%), Gaps = 138/818 (16%)
Query: 1910 GSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGR 1969
G C G+ ++ C D++ECA +CR+G C+N GS++C C G+ + P
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECAMPG--VCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 1970 TCV-----DINEC--LLEPRKCAPGTCQNLDGSYRCICPPG--YSLQNEKCEDIDECVEE 2020
C+ + + C L+ P C C G + + ++C D
Sbjct: 393 QCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRC-PTDGTAAF 451
Query: 2021 PEICALGTCSNTEGSFKCLCPEG---FSL---SSSGRRCQDLRMSYCYA-------KFEG 2067
EIC G + S + L +G FSL + Q L S A + G
Sbjct: 452 KEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERG 511
Query: 2068 GKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFR----QICPYGSGIIVGPDD 2123
SP S S Q+ EL R + P S + + P
Sbjct: 512 VTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAP-T 570
Query: 2124 SAVDMDECK-EPDVCKHGQCINTDGSYRCECPFGYILAGNE--CVDTDECSVGNPC--GN 2178
+ DEC+ ++C HG+C+ Y C C GY CVD +EC PC G
Sbjct: 571 QVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE-AEPCGPGR 629
Query: 2179 GTCKNVIGGFECTCEEGFE---PGPMMTCEDINECAQNPLLCAFR--CVNTYGSYECKCP 2233
G C N G + C C G+ +C D+NECA+ P LC C+N G Y+C C
Sbjct: 630 GICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCNCY 688
Query: 2234 VGYVLREDR-RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI-CGPGYQRRPDGEGCVD 2291
GY L+ R +C+D DEC + C + +C+N G++ CI C PGY R G C D
Sbjct: 689 PGYRLKASRPPVCEDIDECRD-PSSCPDG--KCENKPGSFKCIACQPGY-RSQGGGACRD 744
Query: 2292 ENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIG 2351
NEC + C G C N GS+ C C G+ +P+ CLD E C ++C G
Sbjct: 745 VNEC-AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDE--C---EAGDVCDNG 798
Query: 2352 SSNRNPVTKSECCCDGGRGWG---PHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKV 2408
+ P +C C G HCE DIDEC
Sbjct: 799 ICSNTP-GSFQCQCLSGYHLSRDRSHCE-------------------------DIDECD- 831
Query: 2409 IHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC--NFICKNTEGSY 2466
C G+C+N GSY C+C G+ + G C D++EC+Q P C + CKN +GSY
Sbjct: 832 FPAACIGGDCINTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSY 890
Query: 2467 QCSCPKGYILQEDGRSCKDLDECATKQH---------NCQFLCVNTIGGFTCKCPPG--- 2514
C C +G+ +D C+++++ K+ C + + C C G
Sbjct: 891 VCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW 950
Query: 2515 -------------FTQHHTSCIDNNECTSDINLCG--------------------SKGIC 2541
+ H+ C D T D N+ +G C
Sbjct: 951 GDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKC 1010
Query: 2542 QNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHY 2600
NT + C C++GF D C DVDEC C++G C+N GGYRC+C
Sbjct: 1011 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSP 1070
Query: 2601 QWNQC-----VDENECLSAHICGGASCHNTLGSYKCMC 2633
QC +D +EC C C N GSY+C C
Sbjct: 1071 AQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCEC 1108
Score = 239 bits (609), Expect = 4e-62
Identities = 170/546 (31%), Positives = 236/546 (43%), Gaps = 57/546 (10%)
Query: 2184 VIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRR 2243
V G C +G++ C+DINECA + C+N GSY C CP G+ L R
Sbjct: 333 VRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 2244 MC-KDEDECEEGKHDCTEKQMECKNLIGT----YMCICGPGYQRRPDGEGCVDENECQTK 2298
C D+ E + + +C++ + T +C C G + C + K
Sbjct: 393 QCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFK 452
Query: 2299 PGICENGR---CLNTRGSYTCECNDGFTA---------------SPNQ---DECLDNREG 2337
IC G+ L + + T + F+ SP+Q E + G
Sbjct: 453 E-ICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERG 511
Query: 2338 YCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEIC--PFQGTVA-FKKLCPHGR 2394
+ + S+ T P+ E+ P T+ F P R
Sbjct: 512 VTTDSPVSEERSVQQSHPTATTTPA---------RPYPELISRPSPPTMRWFLPDLPPSR 562
Query: 2395 GFM----TNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQ 2450
+ T + DEC++ ++C +GECV Y C C GY CVD+NEC
Sbjct: 563 SAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA 622
Query: 2451 AP-KPCNFICKNTEGSYQCSCPKGYILQ--EDGRSCKDLDECATKQHNCQF--LCVNTIG 2505
P P IC NT GSY C C +GY L GRSC DL+ECA K H C C+N G
Sbjct: 623 EPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGGFCINFPG 681
Query: 2506 GFTCKCPPGF---TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC-ECQRGFSLDQT 2561
+ C C PG+ C D +EC D + C G C+N PGSF C CQ G+ Q
Sbjct: 682 HYKCNCYPGYRLKASRPPVCEDIDECR-DPSSCPD-GKCENKPGSFKCIACQPGYR-SQG 738
Query: 2562 GSSCEDVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGA 2620
G +C DV+EC C G C+N+ G +RC+C QGY C+D +EC + +C
Sbjct: 739 GGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNG 798
Query: 2621 SCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFR 2680
C NT GS++C C +G+ + C+DI+EC A C NT G Y C CP G+
Sbjct: 799 ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRL 858
Query: 2681 IGQGHC 2686
+G C
Sbjct: 859 VGGRKC 864
Score = 228 bits (580), Expect = 9e-59
Identities = 178/580 (30%), Positives = 233/580 (40%), Gaps = 98/580 (16%)
Query: 2159 LAGNECVDTDECSVG-NPCGNGTCKNVIGGFECTCEEGFEPGPMMT-CEDINECAQNPLL 2216
+A + +TDEC + N CG+G C + C C G+ P C D+NEC P
Sbjct: 567 IAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-- 624
Query: 2217 CAFR---CVNTYGSYECKCPVGYVLREDR--RMCKDEDECEEGKHDCTEKQMECKNLIGT 2271
C C+NT GSY C C GY L R C D +EC + H C + C N G
Sbjct: 625 CGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGF-CINFPGH 682
Query: 2272 YMCICGPGYQRRPDGEG-CVDENECQTKPGICENGRCLNTRGSYTC-ECNDGFTASPNQD 2329
Y C C PGY+ + C D +EC+ P C +G+C N GS+ C C G+ S
Sbjct: 683 YKCNCYPGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSFKCIACQPGYR-SQGGG 740
Query: 2330 ECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKL 2389
C D E + C+ N C C +G+ P
Sbjct: 741 ACRDVNECAEGSPCSPGWCE------NLPGSFRCTC--AQGYAP---------------- 776
Query: 2390 CPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECN 2449
P GR + D+DEC+ DVC NG C N GS+ C C +GY + C D++EC+
Sbjct: 777 APDGRSCL----DVDECEA-GDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD 831
Query: 2450 QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC--QFLCVNTIGGF 2507
C NT GSY+C CP+G+ L GR C+D+DEC+ C C N G +
Sbjct: 832 FPAACIGGDCINTNGSYRCLCPQGHRLV-GGRKCQDIDECSQDPSLCLPHGACKNLQGSY 890
Query: 2508 TCKCPPGFT--------------QHHTSCIDNNECT-----------SDINLCGSKGI-- 2540
C C GFT H C N + T + C S G
Sbjct: 891 VCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW 950
Query: 2541 ---CQNTP------GSFTCECQRGFSLDQTGS-------SCEDVDECE--GNHRCQHG-C 2581
C+ P F C G Q + + D+DEC G+ C+ G C
Sbjct: 951 GDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKC 1010
Query: 2582 QNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQ 2641
N GY C C QG+ +CVD +ECL C C NT G Y+C C +Y
Sbjct: 1011 VNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSP 1070
Query: 2642 FSGGC-----QDINECGSAQAPCSYGCSNTEGGYLCGCPP 2676
C D++EC A C N G Y C C P
Sbjct: 1071 AQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRP 1110
Score = 213 bits (541), Expect = 3e-54
Identities = 216/843 (25%), Positives = 307/843 (36%), Gaps = 206/843 (24%)
Query: 34 VKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCI-VPICR-HSCGD 91
V ET R + G + + GP Y+ +C PG+++ P C+ V C CG
Sbjct: 572 VTETDECRLNQNICGHGECVPGP----PDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGP 627
Query: 92 G--FCSRPN---MCTCPSG-QIAPSCGSRSIQHCNI-----RCMNGGSCSDD----HCLC 136
G C C C G ++ G RS N C +GG C + C C
Sbjct: 628 GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNC 687
Query: 137 QKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQ 196
GY PVCE + C P+ C +CE + C Q
Sbjct: 688 YPGYRLKASRPPVCE----DIDECRDPSSCP------DGKCENKPGSFKCIACQPGYRSQ 737
Query: 197 GQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH-PCRRGFIPNIRTGACQDVDECQAIPG 255
G G C CA CE P C +G+ P +C DVDEC+A
Sbjct: 738 G---GGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA-GD 793
Query: 256 LCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKC 315
+C G C NT GSF+C+C +G+ L+ CEDIDEC P C GG+C NT SY C C
Sbjct: 794 VCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD-FPAACIGGDCINTNGSYRCLC 852
Query: 316 PPGFYTSPDGTRCIDV-----RPGYCYTALTNGRCSN----------------------- 347
P G + G +C D+ P C L +G C N
Sbjct: 853 PQG-HRLVGGRKCQDIDECSQDPSLC---LPHGACKNLQGSYVCVCDEGFTPTQDQHGCE 908
Query: 348 -----------------------QLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATED 384
L ++T+ +CCC G W + P CP+ ++ +
Sbjct: 909 EVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYP--CPVYSSAE 966
Query: 385 FNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRV 444
F+ LC P G V Y P+
Sbjct: 967 FHSLC------------------------------PDGKGYTQDNNIVNYGIPAHRD--- 993
Query: 445 LPVNVTDYCQLV-RYLCQNGRCIPTPGSCRCECNKGFQLDLR-GECIDVDEC-EKNPCAG 501
D C L +C+ G+C+ T C C +GF D EC+DVDEC +++ C
Sbjct: 994 -----IDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRN 1048
Query: 502 GECINNQGSYTCQCRAGYQSTLTRTEC-----RDIDECLQNGRICNNGRCINTDGSFHCV 556
G C N +G Y C C + + + +C D+DEC Q+ C GRC+N GS+ C
Sbjct: 1049 GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDEC-QDPAACRPGRCVNLPGSYRCE 1107
Query: 557 CNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINE 616
C + G++C+ + + R +C ++ G DG
Sbjct: 1108 CRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRG-------------EDGM------- 1147
Query: 617 CETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFG 676
C P + G + D C C G G R C S C
Sbjct: 1148 CAGP---LAGPALTFDD---CCCRQGRGWGAQCRPCPPRGAGSHCP-------------T 1188
Query: 677 AVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN 736
+ ++S ++ G+P + + + C SG + G + E CP
Sbjct: 1189 SQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCE-------CPG 1241
Query: 737 GICENLRGTYKCICNSGYEVDSTGKNCVDINEC-VLN--SLLCDNGQCRNTPGSFVCTCP 793
G +++D++ CVDI+EC LN LLC + +C NT GSF C C
Sbjct: 1242 G----------------FQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCK 1285
Query: 794 KGF 796
GF
Sbjct: 1286 AGF 1288
Score = 208 bits (530), Expect = 5e-53
Identities = 156/504 (30%), Positives = 208/504 (41%), Gaps = 75/504 (14%)
Query: 2206 DINECAQNPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQME 2264
+ +EC N +C CV Y C C GY R C D +ECE C +
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA--EPCGPGRGI 631
Query: 2265 CKNLIGTYMCICGPGYQRR--PDGEGCVDENECQTKPGIC-ENGRCLNTRGSYTCECNDG 2321
C N G+Y C C GY+ G CVD NEC KP +C + G C+N G Y C C G
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKCNCYPG 690
Query: 2322 FTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQ 2381
+ ++ +C+ R+P + C DG CE P
Sbjct: 691 YRLKASRPP----------------VCEDIDECRDPSS----CPDG------KCENKPG- 723
Query: 2382 GTVAFKKL-CPHGRGFMTNGA--DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDIT 2438
+FK + C G GA D++EC C G C N GS+ C C GY P
Sbjct: 724 ---SFKCIACQPGYRSQGGGACRDVNECAE-GSPCSPGWCENLPGSFRCTCAQGYAPAPD 779
Query: 2439 GTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF 2498
G SC+D++EC N IC NT GS+QC C GY L D C+D+DEC
Sbjct: 780 GRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGG 839
Query: 2499 LCVNTIGGFTCKCPPGFTQ-HHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFS 2557
C+NT G + C CP G C D +EC+ D +LC G C+N GS+ C C GF+
Sbjct: 840 DCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 899
Query: 2558 LDQTGSSCEDVDECEGNHRCQHG------CQNIIGG----YRCSCPQGYLQHYQWNQCVD 2607
Q CE+V++ C C +++ C C G W D
Sbjct: 900 PTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGA----GWG---D 952
Query: 2608 ENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSG-------GCQDINECGSAQAP-C 2659
E + A H+ +CP G Y Q + +DI+EC + C
Sbjct: 953 HCEIYPCPVYSSAEFHS-------LCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEIC 1005
Query: 2660 SYG-CSNTEGGYLCGCPPGYFRIG 2682
G C NT+ GY C C G++ G
Sbjct: 1006 KEGKCVNTQPGYECYCKQGFYYDG 1029
Score = 126 bits (317), Expect = 3e-28
Identities = 151/585 (25%), Positives = 205/585 (35%), Gaps = 161/585 (27%)
Query: 57 NVCGSRYNAYCCPGWKTLPGGNQCI-VPICRHS--CGDGFCSRPN---MCTCPSGQIAPS 110
N+ GS + C G+ P G C+ V C C +G CS C C SG
Sbjct: 761 NLPGS-FRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHL-- 817
Query: 111 CGSRSIQHCN--------IRCMNGGSCSDDH----CLCQKGY--IGTHCGQPVCE----- 151
SR HC C+ GG C + + CLC +G+ +G Q + E
Sbjct: 818 --SRDRSHCEDIDECDFPAACI-GGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDP 874
Query: 152 SGCLNGGRCV---APNRCACTYGFTGPQ-------CERDYRTGPCFTVISNQMCQGQLSG 201
S CL G C C C GFT Q E+ + C+ + + +
Sbjct: 875 SLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLA 934
Query: 202 IVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGN 261
T+ CC ++G WG CE+ P + + + C G Q N
Sbjct: 935 TNVTQQECCCSLGAGWGDHCEIYPCPVY------------SSAEFHSLCPDGKGYTQDNN 982
Query: 262 CINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPG-ICEGGECTNTVSSYFCKCPPGFY 320
+N PA H+ DIDEC IC+ G+C NT Y C C GFY
Sbjct: 983 IVNY------GIPA-HR---------DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFY 1026
Query: 321 TSPDGTRCIDV---------RPGYCYTALTNGRCSNQLP--QSITKMQC----------- 358
+ C+DV R G C RC+ P S + QC
Sbjct: 1027 YDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDEC 1086
Query: 359 ----CCDAGRC--------------WSPGVT----VAPEMCPIRATE---------DFNK 387
C GRC W PG + PE RA E +
Sbjct: 1087 QDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDG 1146
Query: 388 LCSVPMVIP---------------GRPEYPPPPLGP---IPPVLPVPPGFPPGPQIPVPR 429
+C+ P+ P G P PP G P F + + +
Sbjct: 1147 MCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGK 1206
Query: 430 PPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDL-RGEC 488
PP + + +D C+ C +GRC+P PG CEC GFQLD R C
Sbjct: 1207 PPRDEDSSEED---------SDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARC 1252
Query: 489 IDVDEC-EKNP----CAGGECINNQGSYTCQCRAGYQSTLTRTEC 528
+D+DEC E N C C+N GS+ C C+AG+ + C
Sbjct: 1253 VDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 109 bits (272), Expect = 4e-23
Identities = 66/189 (34%), Positives = 84/189 (44%), Gaps = 10/189 (5%)
Query: 2520 TSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQH 2579
T + +EC + N+CG G C P ++C C G+ C DV+ECE C
Sbjct: 570 TQVTETDECRLNQNICGH-GECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP-CGP 627
Query: 2580 G---CQNIIGGYRCSCPQGYLQHYQ--WNQCVDENECLSAHICG-GASCHNTLGSYKCMC 2633
G C N G Y C C +GY H CVD NEC H+CG G C N G YKC C
Sbjct: 628 GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNC 687
Query: 2634 PAGFQYEQFSGG-CQDINECGSAQAPCSYGCSNTEGGYLC-GCPPGYFRIGQGHCVSGMG 2691
G++ + C+DI+EC + C N G + C C PGY G G C
Sbjct: 688 YPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 747
Query: 2692 MGRGNPEPP 2700
G+P P
Sbjct: 748 CAEGSPCSP 756
Score = 90.1 bits (222), Expect = 3e-17
Identities = 74/267 (27%), Positives = 96/267 (35%), Gaps = 77/267 (28%)
Query: 460 CQNGRCIPTPGSCRCECNKGFQLD------LRGECIDVDECEKNP-CAGGECINNQGSYT 512
C+NG C T G RC C + L E +DVDEC+ C G C+N GSY
Sbjct: 1046 CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYR 1105
Query: 513 CQCRAGYQSTLTRTEC-------------RDI----------------------DECLQN 537
C+CR + + +C RD+ D+C
Sbjct: 1106 CECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCC-- 1163
Query: 538 GRICNNGR--------CINTDGSFHCVCNA--------------GFHVTRDGKNCEDMDE 575
C GR C HC + G + + ED DE
Sbjct: 1164 ---CRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDE 1220
Query: 576 CSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPG----ICMNGRCVNT 631
C C++G C+ G C C GFQL + C DI+EC +C + RCVNT
Sbjct: 1221 CR----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNT 1276
Query: 632 DGSYRCECFPGLAVGLDGRVCVDTHMR 658
GS+RC C G A CV R
Sbjct: 1277 SGSFRCVCKAGFARSRPHGACVPQRRR 1303
Score = 89.4 bits (220), Expect = 5e-17
Identities = 77/302 (25%), Positives = 107/302 (35%), Gaps = 49/302 (16%)
Query: 63 YNAYCCPGWKTLPGGNQCI-VPIC--RHSCGDGFCSRPN---MCTC-PSGQIAPS---CG 112
Y YC G+ +C+ V C +C +G C C C P + +P+ C
Sbjct: 1017 YECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCL 1076
Query: 113 SRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGF 172
S + C + +C C+ G C P +G C P
Sbjct: 1077 SPEEMDVD-ECQDPAACRPGRCVNLPGSYRCECRPPWVPGP--SGRDCQLPE-------- 1125
Query: 173 TGPQCERDYRTGPCFTVISNQ-MCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQ---- 227
P R C++ MC G L+G T CC GR WG C CP +
Sbjct: 1126 -SPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGS 1184
Query: 228 --------------PHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKC 273
P G P + +D DEC+ C G C+ G C+C
Sbjct: 1185 HCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR-----CVSGRCVPRPGGAVCEC 1239
Query: 274 PAGHKLNEVSQKCEDIDECSTIPG---ICEGGECTNTVSSYFCKCPPGFYTSPDGTRCID 330
P G +L+ +C DIDEC + +C+ C NT S+ C C GF S C+
Sbjct: 1240 PGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVP 1299
Query: 331 VR 332
R
Sbjct: 1300 QR 1301
Score = 86.7 bits (213), Expect = 3e-16
Identities = 65/228 (28%), Positives = 97/228 (42%), Gaps = 60/228 (26%)
Query: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWG-TPCEMCPAVNTS------- 1583
G C+ D P+ G SN + + CC S+G AWG + C CP + +
Sbjct: 277 GRCFQDTLPKQPCG----SNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGP 332
Query: 1584 ---EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLN 1640
E CP G R N + +DI+EC +PG+C+ G C+N GS++C CP G+ L
Sbjct: 333 VRGEVGADCPQGYK-RLN--STHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSL- 387
Query: 1641 EDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYY 1700
GP C D + +SLC+R
Sbjct: 388 ------------------GPSRTQ---------CIADKPE----------EKSLCFRLVS 410
Query: 1701 ADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLC 1748
++Q C L +T+++CCCS +G+AW C++CP T F +C
Sbjct: 411 PEHQ-CQHPLTTRLTRQLCCCS--VGKAWGARCQRCPTDGTAAFKEIC 455
Score = 64.7 bits (156), Expect = 1e-09
Identities = 51/162 (31%), Positives = 71/162 (43%), Gaps = 23/162 (14%)
Query: 1042 GKC-RNTIGSFKCRCDSGFALDSEERNCTDI------DECRISPDLCGRGQCVNTP--GD 1092
G+C ++T+ C + L +E C I +C P L G P G+
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGE 336
Query: 1093 FECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISA 1152
C +GY+ + +C DI+EC P +CR G C N GSYRC CPPGH L P+ +
Sbjct: 337 VGADCPQGYKR--LNSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 1153 CIDINECELSAHLC-----PNGRC----VNLIGKYQCACNPG 1185
CI E S LC P +C + + C C+ G
Sbjct: 394 CIADKPEEKS--LCFRLVSPEHQCQHPLTTRLTRQLCCCSVG 433
Score = 63.5 bits (153), Expect = 3e-09
Identities = 39/127 (30%), Positives = 53/127 (41%), Gaps = 17/127 (13%)
Query: 2070 CSSPKSRNHSKQECCCALKGEGWGDP-CELCPT-------EPDEAFRQI---CPYGSGII 2118
C S +KQE CC G WG C CP +P ++ CP G +
Sbjct: 289 CGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRL 348
Query: 2119 VGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGN 2178
D++EC P VC+HG C+N GSYRC CP G+ L + +C P
Sbjct: 349 --NSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSR----TQCIADKPEEK 402
Query: 2179 GTCKNVI 2185
C ++
Sbjct: 403 SLCFRLV 409
Score = 61.2 bits (147), Expect = 1e-08
Identities = 41/121 (33%), Positives = 57/121 (47%), Gaps = 16/121 (13%)
Query: 2337 GYCFTEVLQNMCQIGSSNRNPVTKSECCCDG-GRGWGPH-CEICPFQGTVAFKKL----- 2389
G CF + L GS+ +TK E CC G WG C CP +K
Sbjct: 277 GRCFQDTLPKQ-PCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRG 335
Query: 2390 -----CPHG--RGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC 2442
CP G R T+ DI+EC + VCR+G+C+N+ GSY C+C G++ + T C
Sbjct: 336 EVGADCPQGYKRLNSTHCQDINEC-AMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Query: 2443 V 2443
+
Sbjct: 395 I 395
Score = 58.9 bits (141), Expect = 7e-08
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 1829 GSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTM 1888
G DC GY+ ++ C D NEC +P +C HG C++ GS+ C+C G +T
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQ 393
Query: 1889 CLDINECERDAC 1900
C+ E+ C
Sbjct: 394 CIADKPEEKSLC 405
Score = 55.1 bits (131), Expect = 1e-06
Identities = 45/146 (30%), Positives = 60/146 (41%), Gaps = 40/146 (27%)
Query: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKP-CEQCPIPSTDEFATLCGSQRPGFVIDIYTG 1762
Q C L +TK+ CC +IG AW + C +CP G Q+PG
Sbjct: 287 QPCGSNPLPGLTKQEDCCG-SIGTAWGQSKCHKCPQ------LQYTGVQKPG-------- 331
Query: 1763 LPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNA 1822
PV G +CP G+ + C+DI+EC VC R+
Sbjct: 332 -PVR--------------------GEVGADCPQGYKRLNSTH-CQDINECAMPGVC-RHG 368
Query: 1823 ECINTAGSYRCDCKPGYRF-TSTGQC 1847
+C+N GSYRC C PG+ S QC
Sbjct: 369 DCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 48.1 bits (113), Expect = 1e-04
Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 13/83 (15%)
Query: 2565 CEDVDECEGNHRCQHGCQN-----------IIGGYRCSCPQGYLQHYQWNQCVDENECLS 2613
C + G +C H C + G CPQGY + C D NEC
Sbjct: 304 CGSIGTAWGQSKC-HKCPQLQYTGVQKPGPVRGEVGADCPQGY-KRLNSTHCQDINECAM 361
Query: 2614 AHICGGASCHNTLGSYKCMCPAG 2636
+C C N GSY+C+CP G
Sbjct: 362 PGVCRHGDCLNNPGSYRCVCPPG 384
Score = 39.3 bits (90), Expect = 0.057
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 19/75 (25%)
Query: 119 CNIRCMNGGSCSDDHCLCQKGYIGTHCGQP---------------VCESGCLNGGRCVAP 163
C C+ G C D CQ+G T G+ VC C+NGG+C +
Sbjct: 71 CKRTCLKG-QCRDS---CQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSR 126
Query: 164 NRCACTYGFTGPQCE 178
N+C C FTG C+
Sbjct: 127 NQCLCPPDFTGRFCQ 141
Score = 38.9 bits (89), Expect = 0.074
Identities = 35/118 (29%), Positives = 43/118 (36%), Gaps = 11/118 (9%)
Query: 42 AKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCT 101
A RG GG AL R+ P + C+ CR SC G
Sbjct: 46 AGERGAGGGGAL-----ARERFKVVFAP----VICKRTCLKGQCRDSCQQGSNMTLIGEN 96
Query: 102 CPSGQIAPSCGSRSIQHCNIRCMNGGSCSD-DHCLCQKGYIGTHCGQPVCESGCLNGG 158
S G R + C + CMNGG CS + CLC + G C P +G GG
Sbjct: 97 GHSTDTLTGSGFRVVV-CPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGG 153
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 334 bits (856), Expect = 9e-91
Identities = 377/1379 (27%), Positives = 535/1379 (38%), Gaps = 313/1379 (22%)
Query: 1415 CGNG-QCLNAPGGY-RCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCEC 1472
C NG CL+ G C+C GF+ G+ C+ D C +C
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLC---------------- 74
Query: 1473 EIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVD---- 1528
++GG+C + P S TP S++C C P F + D
Sbjct: 75 -------QNGGSCQALLPA--PLGLPSSPSPLTP-SFLCTCLPGFTGERCQAKLEDPCPP 124
Query: 1529 ---TRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAW-GTPCEM---C---P 1578
++ G C++ R C C G W G C++ C P
Sbjct: 125 SFCSKRGRCHIQASGR------------------PQCSCMPG--WTGEQCQLRDFCSANP 164
Query: 1579 AVN-----TSEYKILCPGGEGFRPNPITVILEDIDECQELPGLC-QGGKCINTFGSFQCR 1632
VN + +I C GF + D++EC + PG C +G C NT GSFQC
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACE---RDVNECFQDPGPCPKGTSCHNTLGSFQCL 221
Query: 1633 CPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGN----YTCICPPDYMQVNGGNNCM 1688
CP G E R C G GTC + C+CPP ++ G +C
Sbjct: 222 CPVG---QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI----GPDC- 273
Query: 1689 DMRRSLCYRNYYADNQTCDGEL-----LFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDE 1743
++ C + + TC L L T CS ++ + C T +
Sbjct: 274 EVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQ 333
Query: 1744 -----FATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENG-VCINMVGSFRCECPVGF 1797
F +C S G T ++D+C I C G CI+ VGSF C CP G
Sbjct: 334 NSAGSFHCVCVSGWGG------TSCEENLDDC--IAATCAPGSTCIDRVGSFSCLCPPG- 384
Query: 1798 FYNDKLLVCEDIDECQNGPVCQRNAECINT--AGSYRCDCKPGYRFTSTGQCNDRNEC-- 1853
L+C D C + P C +A+C GS C C+PGY + Q D +EC
Sbjct: 385 ---RTGLLCHLEDMCLSQP-CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLM 438
Query: 1854 -QEIPNICSHG-QCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNG-TCRNTIG 1910
Q+ P+ C HG C++T GSF CLC G+ + + D NEC C G TC + +
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEA---DHNECLSQPCHPGSTCLDLLA 495
Query: 1911 SFNCRCNHGFILSHNNDC-IDVDECASGNGNLCRN-GQCINTVGSFQCQCNEGYEVAPDG 1968
+F+C C G C ++ +ECAS C N C + + FQC C G+ G
Sbjct: 496 TFHCLCPPGL---EGQLCEVETNECASAP---CLNHADCHDLLNGFQCICLPGFS----G 545
Query: 1969 RTCV-DINECLLEPRKCAPG-TCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICA 2025
C DI+EC P CA G CQ+ G++ C C PG+ + +C+ ++DEC+ +P C
Sbjct: 546 TRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF--EGPRCQTEVDECLSDP--CP 599
Query: 2026 LG-TCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECC 2084
+G +C + G+F CLCP GF+ G C P + Q
Sbjct: 600 VGASCLDLPGAFFCLCPSGFT---------------------GQLCEVPLCAPNLCQ--- 635
Query: 2085 CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCIN 2144
P ++C + D+A +CP GS P+D+ C HG C
Sbjct: 636 ----------PKQICKDQKDKA-NCLCPDGSPGCAPPEDNCT----------CHHGHCQR 674
Query: 2145 TDGSYRCECPFGYILAGNECVDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMT 2203
+ C C G+ G EC + PC +G TC G+ CTC G+ GP T
Sbjct: 675 SS----CVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT-GP--T 725
Query: 2204 C-EDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQ 2262
C E++ C P L C + G Y C CP + +C+ C
Sbjct: 726 CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----------GPQCQTSTDYCVSAP 775
Query: 2263 M----ECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICEN-GRCLNTRGSYTCE 2317
C N GT+ C+C G+Q P EG + + C P C N C ++ C
Sbjct: 776 CFNGGTCVNRPGTFSCLCAMGFQG-PRCEGKLRPS-CADSP--CRNRATCQDSPQGPRCL 831
Query: 2318 CNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEI 2377
C G+T G C T L ++C + P ++ C G + HC +
Sbjct: 832 CPTGYTG------------GSCQT--LMDLCA-----QKPCPRNSHCLQTGPSF--HC-L 869
Query: 2378 C--PFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGE-CVNDRGSYHCICKTGYT 2434
C + G + L + ++ G D+ +C NG CV+ SY C C G+
Sbjct: 870 CLQGWTGPLCNLPLSSCQKAALSQGIDVSS------LCHNGGLCVDSGPSYFCHCPPGFQ 923
Query: 2435 PDITGTSCVD-LNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSC-KDLDECATK 2492
G+ C D +N C P C Y C C GY DG++C K+LD C ++
Sbjct: 924 ----GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQ 975
Query: 2493 QHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCEC 2552
+ C GGF C CPPGF D +EC C + +F C+C
Sbjct: 976 PCHNHGTCTPKPGGFHCACPPGFVGLRCEG-DVDECLDQPCHPTGTAACHSLANAFYCQC 1034
Query: 2553 QRGFSLDQTGSSCE-DVDECEGNHRCQHG--CQNIIG---GYRCSCPQGYLQHYQWNQCV 2606
G TG CE ++D C + C HG C+ G G+ C CP+G ++ C
Sbjct: 1035 LPG----HTGQWCEVEIDPCH-SQPCFHGGTCEATAGSPLGFICHCPKG----FEGPTCS 1085
Query: 2607 DENECLSAHIC--GGASCHNTLGSY--KCMCPAGFQYEQFSGGCQDINE-----CGSAQA 2657
H C GG + + +C C +G+ GG + CG +
Sbjct: 1086 HRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY------GGPDCLTPPAPKGCG-PPS 1138
Query: 2658 PCSY--GCSNTEG----GYLCGCP---PG-----------YFRIGQGHCVSGMGMGRGN 2696
PC Y CS T G G+ C CP PG R G G C +G GN
Sbjct: 1139 PCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
Score = 320 bits (820), Expect = 1e-86
Identities = 360/1327 (27%), Positives = 501/1327 (37%), Gaps = 281/1327 (21%)
Query: 914 CEVFPGVCKNG-LCVN-TRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPI 971
C FP C NG C++ + G CQC G ETC + L
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLG------------ETCQFPDPCQNAQLCQ 75
Query: 972 AGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
G +C + A G P TP + LC PGF T + K +
Sbjct: 76 NG----GSCQALLPAPLGLPSS---PSPLTPSF--LCTCLPGF-----TGERCQAKLEDP 121
Query: 1032 CKMIPSLCT-HGKCR-NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
C PS C+ G+C G +C C G+ + C D C +P + G G C+ T
Sbjct: 122 CP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQ----CQLRDFCSANPCVNG-GVCLAT 174
Query: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC-RGGVCHNTEGSYRCECPPGHQLSP 1148
+C C G+E D++EC +DP C +G CHNT GS++C CP G + P
Sbjct: 175 YPQIQCHCPPGFEGHACER----DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GP 229
Query: 1149 NISACIDINECELSAHLCP-----NGRCVNLIGK-----YQCACNPGYHSTPDRLFC-VD 1197
CEL A CP NG L+ + + C C PG+ PD C V+
Sbjct: 230 R---------CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIG-PD---CEVN 276
Query: 1198 IDEC---SIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCT-DIDECEDN--PNICDG 1251
D C NGG C + +Y C C + C+ D+DECE P+ +G
Sbjct: 277 PDNCVSHQCQNGGT---CQDGLDTYTCLCPETWTGW----DCSEDVDECETQGPPHCRNG 329
Query: 1252 GQCTNIPGEYRCLCYDGF---MASEDMKTCVDVN--------------ECDLNP------ 1288
G C N G + C+C G+ E++ C+ C P
Sbjct: 330 GTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLL 389
Query: 1289 ----NICLSGTCENTK--------GSFICHCDMGYSGKKGKTGCTDINEC---EIGAHNC 1333
++CLS C GS +C C GYSG T D++EC + G C
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP---TCHQDLDECLMAQQGPSPC 446
Query: 1334 GKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKE 1393
C NT GSF C C PG+ G + D +EC + C + C + + ++ CLC
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGYTGSRCE-ADHNECL--SQPCHPGSTCLDLLATFHCLCPP 503
Query: 1394 GYTGDGFTCTDLDECSENLNLCGNGQCLNAP------GGYRCECDMGFVPSADGKAC-ED 1446
G G C N C + CLN G++C C +P G C ED
Sbjct: 504 GLEG--------QLCEVETNECASAPCLNHADCHDLLNGFQCIC----LPGFSGTRCEED 551
Query: 1447 IDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCISGNCVNT 1505
IDEC G C + PG F C+C G+E G C T+V+ECL + +C++
Sbjct: 552 IDECRSSPCANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDL 607
Query: 1506 PGSYICDCPPDF------------ELNPTRVGCVDTR-SGNCYLDIRPRGDNG----DTA 1548
PG++ C CP F L + C D + NC + P G G +
Sbjct: 608 PGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANC---LCPDGSPGCAPPEDN 664
Query: 1549 CSNEIGVGVSKASCCCSLGKAWGTP--------CEMCPAVN-------TSEYKILCPGGE 1593
C+ G ++SC C +G W P C P + S Y CP G
Sbjct: 665 CTCHHG-HCQRSSCVCDVG--WTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG- 720
Query: 1594 GFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCP---TGYYLNEDTRVCDDVN 1650
P E++ C P L GG C + G + C CP TG T C
Sbjct: 721 --YTGP--TCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC---- 771
Query: 1651 ECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGEL 1710
P G GTC N G ++C+C + G C R C + + TC
Sbjct: 772 -VSAPCFNG-GTCVNRPGTFSCLCAMGFQ----GPRCEGKLRPSCADSPCRNRATCQDSP 825
Query: 1711 LFNMTKKMCCCSYNIG--RAWNKPCEQCPIPSTD-------EFATLC--GSQRPGFVIDI 1759
+ +C Y G + C Q P P F LC G P + +
Sbjct: 826 --QGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPL 883
Query: 1760 YTGLPVDIDECREIPGVCEN-GVCINMVGSFRCECPVGFFYNDKLLVCED-IDECQNGPV 1817
+ + + ++ +C N G+C++ S+ C CP GF + +C+D ++ C++ P
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRP- 938
Query: 1818 CQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCH 1877
CQ A C+ Y C C PGY + + + + CQ P +HG C G F+C C
Sbjct: 939 CQNGATCMAQPSGYLCQCAPGYDGQNCSK--ELDACQSQP-CHNHGTCTPKPGGFHCACP 995
Query: 1878 TGF---KTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDEC 1934
GF + D CLD C G C + +F C+C G H +V+
Sbjct: 996 PGFVGLRCEGDVDECLD-QPCH--PTGTAACHSLANAFYCQCLPG----HTGQWCEVEID 1048
Query: 1935 ASGNGNLCRNGQCINTVGS---FQCQCNEGYE------VAPD--GRTCVDINECLLEPRK 1983
+ G C T GS F C C +G+E AP C CL P+
Sbjct: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKP 1108
Query: 1984 CAPGTCQNLD--GSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEG----SFK 2037
P C L G C+ PP + C C+ G+CS T G F+
Sbjct: 1109 GFPPRCACLSGYGGPDCLTPPA----PKGCGPPSPCLYN------GSCSETTGLGGPGFR 1158
Query: 2038 CLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGW-GDPC 2096
C CP SS G RCQ C + G C + C+ G W G C
Sbjct: 1159 CSCPH----SSPGPRCQKPGAKGCEGRSGDGAC-----------DAGCSGPGGNWDGGDC 1203
Query: 2097 ELCPTEP 2103
L +P
Sbjct: 1204 SLGVPDP 1210
Score = 317 bits (812), Expect = 1e-85
Identities = 363/1316 (27%), Positives = 509/1316 (38%), Gaps = 320/1316 (24%)
Query: 460 CQNG-RCIPTP-GSCRCECNKGFQLDLRGECIDVDECEKNPCA--GGEC----------- 504
C NG C+ G C+C GF L C D C+ GG C
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGF---LGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLP 91
Query: 505 ---INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNN-GRC-INTDGSFHCVCNA 559
S+ C C G+ T R + + D C + C+ GRC I G C C
Sbjct: 92 SSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPS--FCSKRGRCHIQASGRPQCSCMP 147
Query: 560 GFHVTRDGKNCEDMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYC-KDINEC 617
G+ G+ C+ D CS N C+NG +C+ +C C PGF +G C +D+NEC
Sbjct: 148 GW----TGEQCQLRDFCSA-NPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNEC 198
Query: 618 -ETPGICMNG-RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLF 675
+ PG C G C NT GS++C C VG +G C + G C P
Sbjct: 199 FQDPGPCPKGTSCHNTLGSFQCLC----PVGQEGPRC-----------ELRAGPC--PPR 241
Query: 676 GAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICP 735
G C++ G CQ P ++S + LC PG +C ++PD C
Sbjct: 242 G--------CSN-----GGTCQLMPEKDSTFHLCLCP--PGFIGP-----DCEVNPDNCV 281
Query: 736 N------GICENLRGTYKCICNSGYEVDSTGKNC-VDINEC-VLNSLLCDN-GQCRNTPG 786
+ G C++ TY C+C + TG +C D++EC C N G C+N+ G
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337
Query: 787 SFVCTCPKGFIYKPDLKTCED-IDECESSPCING-VCKNSPGSFICECSSESTLDPTKTI 844
SF C C G+ +CE+ +D+C ++ C G C + GSF C C P +T
Sbjct: 338 SFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC------PPGRTG 387
Query: 845 CIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIK 904
+ ++ C G + + N T GS TLC +C GYS
Sbjct: 388 LLCHLEDMCLSQPCHGDAQCSTNPLT-------------GS--TLC----LCQPGYS--- 425
Query: 905 GTQC-EDIDEC---EVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCF 959
G C +D+DEC + P C++ G C+NT GSF C CP G TG C
Sbjct: 426 GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRC--------- 472
Query: 960 LRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEI 1019
+ EC ++ + C + A T C LCP G
Sbjct: 473 -EADHNEC---LSQPCHPGSTCLDLLA---TFHC-------------LCPPG-------- 504
Query: 1020 TNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPD 1079
G+ + NEC P L H C + + F+C C GF S R DIDECR SP
Sbjct: 505 LEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPC 560
Query: 1080 LCGRGQCVNTPGDFECKCDEGYESGFMMMKNCM-DIDECQRDPLLCRGGVCHNTEGSYRC 1138
G GQC + PG F CKC G+E C ++DEC DP G C + G++ C
Sbjct: 561 ANG-GQCQDQPGAFHCKCLPGFEG-----PRCQTEVDECLSDPCPV-GASCLDLPGAFFC 613
Query: 1139 ECPPGHQ--------LSPNISACIDI--NECELSAHLCPNGRCVNLIGKYQCACNPGYHS 1188
CP G +PN+ I ++ + + LCP+G + C C +H
Sbjct: 614 LCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTC---HHG 670
Query: 1189 TPDRLFCV-DI----DECSIMNGGCET-------FCTNSEGSYECSCQPGFALMPDQRSC 1236
R CV D+ EC GGC + C Y C+C G+
Sbjct: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT---GPTCS 727
Query: 1237 TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLS--- 1293
++ C P + +GG C PG Y C C +C + + C+S
Sbjct: 728 EEMTACHSGPCL-NGGSCNPSPGGYYCTCPPSHTGP----------QCQTSTDYCVSAPC 776
Query: 1294 ---GTCENTKGSFICHCDMGYSGK----KGKTGCTDINECEIGAHNCGKHAVCTNTAGSF 1346
GTC N G+F C C MG+ G K + C D C A C ++
Sbjct: 777 FNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD--------SPCRNRATCQDSPQGP 828
Query: 1347 KCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLD 1406
+C C G+ G + T +D C+ C +++ C T S+ CLC +G+TG L
Sbjct: 829 RCLCPTGYTGGSCQ-TLMDLCAQ--KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLS 884
Query: 1407 ECSENL--------NLCGN-GQCLNAPGGYRCECDMGFVPSADGKACED-IDECSLPNIC 1456
C + +LC N G C+++ Y C C GF G C+D ++ C
Sbjct: 885 SCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQ 940
Query: 1457 VFGTCHNLPGLFRCECEIGYELDRSGGNCT-DVNECLDPTTCISGNCVNTPGSYICDCPP 1515
TC P + C+C GY+ G NC+ +++ C G C PG + C CPP
Sbjct: 941 NGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 1516 DFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCE 1575
F VG + LD +P G AC + ++ A C L G CE
Sbjct: 997 GF------VGLRCEGDVDECLD-QPCHPTGTAACHS-----LANAFYCQCLPGHTGQWCE 1044
Query: 1576 MCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGS---FQCR 1632
+ +ID C P GG C T GS F C
Sbjct: 1045 V-----------------------------EIDPCHSQP-CFHGGTCEATAGSPLGFICH 1074
Query: 1633 CPTGY---YLNEDTRVCDDVNECETPGICGPG---------TCYNTVGNYTCICPP 1676
CP G+ + C + C G+C P C + G C+ PP
Sbjct: 1075 CPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPP 1129
Score = 251 bits (642), Expect = 6e-66
Identities = 350/1431 (24%), Positives = 489/1431 (34%), Gaps = 331/1431 (23%)
Query: 99 MCTCPSGQIAPSCGSRSIQHCNIR-CMNGGSC-----SDDHCLCQKGYIGTHCG-QPVCE 151
+CTC G C ++ C C G C C C G+ G C + C
Sbjct: 102 LCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCS 161
Query: 152 SG-CLNGGRCVAPN---RCACTYGFTGPQCERDYRT-----GPCFTVISNQMCQGQLSGI 202
+ C+NGG C+A +C C GF G CERD GPC S C L
Sbjct: 162 ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTS---CHNTLGSF 218
Query: 203 VCTKTLCCATVGRAWGHPCEMC--PAQPHPCRRGFIPNIRTGACQDVDE----------- 249
C LC VG+ G CE+ P P C G G CQ + E
Sbjct: 219 QC---LC--PVGQE-GPRCELRAGPCPPRGCSNG-------GTCQLMPEKDSTFHLCLCP 265
Query: 250 -------CQAIPGLC------QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTI- 295
C+ P C GG C + + ++ C CP + S ED+DEC T
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS---EDVDECETQG 322
Query: 296 -PGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCID-VRPGYCYTALTNGRCSNQLPQSI 353
P GG C N+ S+ C C G+ GT C + + T C ++ +
Sbjct: 323 PPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR----V 374
Query: 354 TKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVL 413
C C GR LC + + +P + P
Sbjct: 375 GSFSCLCPPGRT--------------------GLLCHLEDMCLSQPCHGDAQCSTNPLTG 414
Query: 414 PVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCR 473
PG P ++ +++ P C+ G C+ TPGS
Sbjct: 415 STLCLCQPGYSGPTCHQDLDECLMAQQGPSP--------CE------HGGSCLNTPGSFN 460
Query: 474 CECNKGFQLDLRGEC-IDVDECEKNPC-AGGECINNQGSYTCQCRAGYQSTLTRTECRDI 531
C C G+ C D +EC PC G C++ ++ C C G + L E
Sbjct: 461 CLCPPGYT---GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVET--- 514
Query: 532 DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLNGMCINE 590
+EC + N+ C + F C+C GF TR CE D+DEC G C ++
Sbjct: 515 NECA-SAPCLNHADCHDLLNGFQCICLPGFSGTR----CEEDIDECRSSPCANGGQCQDQ 569
Query: 591 DGSFKCICKPGFQLASDGRYCK-DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDG 649
G+F C C PGF +G C+ +++EC + + C++ G++ C C G G
Sbjct: 570 PGAFHCKCLPGF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLC----PSGFTG 621
Query: 650 RVC-VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQ 708
++C V + C + Q K K+ C C P C + +
Sbjct: 622 QLCEVPLCAPNLC----QPKQICK---DQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQR 674
Query: 709 ALCSSGPGMT--SAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDI 766
+ C G T +++ C P G C Y C C +GY TG C +
Sbjct: 675 SSCVCDVGWTGPECEAELGGCISAP-CAHGGTCYPQPSGYNCTCPTGY----TGPTCSEE 729
Query: 767 NECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCIN-GVCKNSP 825
+ + G C +PG + CTCP P +T D C S+PC N G C N P
Sbjct: 730 MTACHSGPCLNGGSCNPSPGGYYCTCPPSHT-GPQCQT--STDYCVSAPCFNGGTCVNRP 786
Query: 826 GSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGS 885
G+F C +C +G RCE L+ C S
Sbjct: 787 GTFSC-------------LCAMGFQGP--------RCE-----GKLRPSCAD-------S 813
Query: 886 PC---TLCQVDP-----ICGKGYSRIKGTQCEDI-DECEVFPGVCKNGLCVNTRGSFKCQ 936
PC CQ P +C GY+ G C+ + D C P +N C+ T SF C
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYT---GGSCQTLMDLCAQKP-CPRNSHCLQTGPSFHCL 869
Query: 937 CPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEEC 996
C G T C LP++ C + G + C
Sbjct: 870 CLQGWT---------------------GPLCNLPLSS-------CQKAALSQGIDVSSLC 901
Query: 997 P-----MRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHG-KCRNTIGS 1050
+ + P Y CP PGF G +N C+ P C +G C
Sbjct: 902 HNGGLCVDSGPSYFCHCP--PGF------QGSLCQDHVNPCESRP--CQNGATCMAQPSG 951
Query: 1051 FKCRCDSGFALDSEERNCT-DIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMK 1109
+ C+C G+ + +NC+ ++D C+ P G C PG F C C GF+ ++
Sbjct: 952 YLCQCAPGY----DGQNCSKELDACQSQP-CHNHGTCTPKPGGFHCAC----PPGFVGLR 1002
Query: 1110 NCMDIDECQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPN 1168
D+DEC P G CH+ ++ C+C PGH CE+ C
Sbjct: 1003 CEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGH----------TGQWCEVEIDPC-- 1050
Query: 1169 GRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFA 1228
HS P G CE + G + C C GF
Sbjct: 1051 ------------------HSQP-----------CFHGGTCEATAGSPLG-FICHCPKGF- 1079
Query: 1229 LMPDQRSCTDIDECEDNPNICDGGQCTNIPG---EYRCLCYDGFMASEDMKTCVDVNECD 1285
+ +C+ + GG C P RC C G+ D T C
Sbjct: 1080 ---EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGPDCLTPPAPKGCG 1135
Query: 1286 LNPNICL-SGTCENTKG----SFICHCDMGYSG----KKGKTGCTDINECEIGAHNCGKH 1336
P+ CL +G+C T G F C C G K G GC E G C
Sbjct: 1136 -PPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGC----EGRSGDGAC--D 1188
Query: 1337 AVCTNTAGSFK-CSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY 1395
A C+ G++ CS G C C + + C S CL
Sbjct: 1189 AGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRC----WLLFRDGQCHPQCDSEECLF---- 1240
Query: 1396 TGDGFTCTDLDECSENLN-LC----GNGQCLNAPGGYRCECDMGFVPSADG 1441
DG+ C C+ + C NG C C D G DG
Sbjct: 1241 --DGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDG 1289
Score = 213 bits (542), Expect = 2e-54
Identities = 292/1150 (25%), Positives = 392/1150 (34%), Gaps = 265/1150 (23%)
Query: 98 NMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD----HCLCQKGYIGTHCGQPV--CE 151
++C CP G I P C + +C NGG+C D CLC + + G C + V CE
Sbjct: 260 HLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE 319
Query: 152 S----GCLNGGRC---VAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 204
+ C NGG C C C G+ G CE + T C ++ C
Sbjct: 320 TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC 379
Query: 205 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGAC--------------QDVDEC 250
LC H +MC +QP N TG+ QD+DEC
Sbjct: 380 ---LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436
Query: 251 ---QAIPGLCQ-GGNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICE-GGEC 304
Q P C+ GG+C+NT GSF C CP G+ +CE D +EC + P C G C
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQP--CHPGSTC 490
Query: 305 TNTVSSYFCKCPPGF------------YTSP--DGTRCIDVRPGY---CYTALTNGRCSN 347
+ ++++ C CPPG ++P + C D+ G+ C + RC
Sbjct: 491 LDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE 550
Query: 348 QLPQSITKMQCCCDAGRCW-SPGV-------TVAPEMCPIRATEDFNKLCSVP---MVIP 396
+ + + C + G+C PG C E + C V + +P
Sbjct: 551 DIDE--CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLP 608
Query: 397 GR-----PEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTD 451
G P L +P L P P + L P P P D
Sbjct: 609 GAFFCLCPSGFTGQLCEVP--LCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPP---ED 663
Query: 452 YCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQGS 510
C CQ C+ G EC + +L G C PCA GG C
Sbjct: 664 NCTCHHGHCQRSSCVCDVGWTGPEC----EAELGG-------CISAPCAHGGTCYPQPSG 712
Query: 511 YTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNC 570
Y C C GY T C + +G N G C + G ++C C + G C
Sbjct: 713 YNCTCPTGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPP----SHTGPQC 764
Query: 571 EDMDECSIRNMCLN-GMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCV 629
+ + + C N G C+N G+F C+C GFQ G C E + C + C
Sbjct: 765 QTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQ----GPRC----EGKLRPSCADSPCR 816
Query: 630 NTDGSYRCECFPGLAVGLDGRVCVDTHM--RSTCYGGYKRGQCIKPLFGAVTKSECCCAS 687
N C D+ R C GY G C T + C
Sbjct: 817 NR------------------ATCQDSPQGPRCLCPTGYTGGSC-------QTLMDLCAQ- 850
Query: 688 TEYAFGEPCQPCP-----AQNSAEYQALCS---SGPGMTSAGSDINECALDPDI-----C 734
+PCP Q + LC +GP S + AL I C
Sbjct: 851 ---------KPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
Query: 735 PN-GICENLRGTYKCICNSGYEVDSTGKNCVD-INECVLNSLLCDNG-QCRNTPGSFVCT 791
N G+C + +Y C C G++ G C D +N C S C NG C P ++C
Sbjct: 902 HNGGLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPC--ESRPCQNGATCMAQPSGYLCQ 955
Query: 792 CPKGFIYKPDLKTC-EDIDECESSPCIN-GVCKNSPGSFICECSSESTLDPTKTICIETI 849
C G+ D + C +++D C+S PC N G C PG F C C + E +
Sbjct: 956 CAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECL 1011
Query: 850 KGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE 909
C T + C SL A+ CQ C G++ G CE
Sbjct: 1012 DQPCHPT---------------GTAACHSLANAF-----YCQ----CLPGHT---GQWCE 1044
Query: 910 -DIDECEVFPGVCKNGLCVNTRGS---FKCQCPSGMTLDATGRICLDIRLETCFLRYEDE 965
+ID C P G C T GS F C CP G G C F
Sbjct: 1045 VEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPKGF----EGPTCSHRAPSCGFHHCHHG 1099
Query: 966 ECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPF 1025
LP C C G +G +C P P+G G
Sbjct: 1100 GLCLPSPKPGFPPRCACLSG--YGGPDCLTPP----------APKGCG------------ 1135
Query: 1026 FKDINECKMIPSLCTH-GKCRNTIG----SFKCRCDSGFALDSEERNCTDIDECRISPDL 1080
PS C + G C T G F+C C ++ E R
Sbjct: 1136 ---------PPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA 1186
Query: 1081 CGRGQCVNTPGDFE-CKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGS---- 1135
C G C G+++ C G + K C C LL R G CH S
Sbjct: 1187 CDAG-CSGPGGNWDGGDCSLGVPDPW---KGCPSHSRCW---LLFRDGQCHPQCDSEECL 1239
Query: 1136 ---YRCECPP 1142
Y CE PP
Sbjct: 1240 FDGYDCETPP 1249
Score = 190 bits (482), Expect = 2e-47
Identities = 180/597 (30%), Positives = 249/597 (41%), Gaps = 99/597 (16%)
Query: 2134 PDVCKHG-QCINTD-GSYRCECPFGYILAGNECVDTDECSVGNPCGNG-TCKNVIGG--- 2187
P+ C +G C++ G C+C G++ G C D C C NG +C+ ++
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFL--GETCQFPDPCQNAQLCQNGGSCQALLPAPLG 89
Query: 2188 -----------FECTCEEGFEPGPMMTCEDINECAQNPLLCAFR--C-VNTYGSYECKCP 2233
F CTC GF C+ E P C+ R C + G +C C
Sbjct: 90 LPSSPSPLTPSFLCTCLPGFTGE---RCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 2234 VGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCV-DE 2292
G+ + C+ D C + C + C C C PG++ G C D
Sbjct: 147 PGWTGEQ----CQLRDFCSA--NPCVNGGV-CLATYPQIQCHCPPGFE----GHACERDV 195
Query: 2293 NECQTKPGICENGR-CLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQN--MCQ 2349
NEC PG C G C NT GS+ C C G + + R G C N CQ
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVG-----QEGPRCELRAGPCPPRGCSNGGTCQ 250
Query: 2350 IGSSNRNPVTKSECCCDGGRGWGPHCEICPFQ--------------GTVAFKKLCPHGRG 2395
+ + T C C G GP CE+ P G + LCP
Sbjct: 251 LMPEKDS--TFHLCLCPPGF-IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT 307
Query: 2396 FMTNGADIDECKVIHDV-CRNG-ECVNDRGSYHCICKTGYTPDITGTSCVD-LNECNQAP 2452
D+DEC+ CRNG C N GS+HC+C +G+ GTSC + L++C A
Sbjct: 308 GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWG----GTSCEENLDDCIAAT 363
Query: 2453 KPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLC-VNTIGGFT-CK 2510
C + GS+ C CP G G C D C ++ + C N + G T C
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPG----RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCL 419
Query: 2511 CPPGFTQHHTSCIDNNECT---SDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE- 2566
C PG++ T D +EC + C G C NTPGSF C C G+ TGS CE
Sbjct: 420 CQPGYSGP-TCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEA 474
Query: 2567 DVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQC-VDENECLSAHICGGASCH 2623
D +EC + C G C +++ + C CP G + C V+ NEC SA A CH
Sbjct: 475 DHNECL-SQPCHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNECASAPCLNHADCH 529
Query: 2624 NTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG--CSNTEGGYLCGCPPGY 2678
+ L ++C+C GF + +DI+EC S +PC+ G C + G + C C PG+
Sbjct: 530 DLLNGFQCICLPGFSGTRCE---EDIDECRS--SPCANGGQCQDQPGAFHCKCLPGF 581
Score = 176 bits (446), Expect = 3e-43
Identities = 231/880 (26%), Positives = 314/880 (35%), Gaps = 218/880 (24%)
Query: 57 NVCGSRYNAYCCPGWKTLPGGNQC---IVPICRHSCGDGFCSRPNM----CTCPSGQIAP 109
N GS ++ C GW GG C + +C G + C CP G+
Sbjct: 334 NSAGS-FHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGL 388
Query: 110 SCGSRSIQ-----HCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCE--------SGCLN 156
C + H + +C CLCQ GY G C Q + E S C +
Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH 448
Query: 157 GGRCV---APNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATV 213
GG C+ C C G+TG +CE D+ C + Q C + + T C
Sbjct: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHNE--CLS----QPCHPGSTCLDLLATFHC--- 499
Query: 214 GRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQ-DVDECQAIPGLCQGGNCINTVGSFECK 272
+CP P + C+ + +EC + P L +C + + F+C
Sbjct: 500 ---------LCP-----------PGLEGQLCEVETNECASAPCL-NHADCHDLLNGFQCI 538
Query: 273 CPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFY----------- 320
C G +CE DIDEC + P GG+C + ++ CKC PGF
Sbjct: 539 CLPGFS----GTRCEEDIDECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDEC 593
Query: 321 ---TSPDGTRCIDVRPG----YCYTALTNGRCSNQL-------PQSITKMQ-----CCCD 361
P G C+D+ PG C + T C L P+ I K Q C C
Sbjct: 594 LSDPCPVGASCLDL-PGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCP 652
Query: 362 AGRCWSPGVTVAPEMCPIR--ATEDFNKLCSVPMVIP----------------GRPEYPP 403
G SPG + C + + +C V P G YP
Sbjct: 653 DG---SPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
Query: 404 P-------PLGPIPPVLPVP-------PGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNV 449
P P G P P G P P PS P+
Sbjct: 710 PSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQC--QTS 767
Query: 450 TDYCQLVRYLCQN-GRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAG-GECINN 507
TDYC V C N G C+ PG+ C C GFQ R E C +PC C ++
Sbjct: 768 TDYC--VSAPCFNGGTCVNRPGTFSCLCAMGFQ-GPRCEGKLRPSCADSPCRNRATCQDS 824
Query: 508 QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDG 567
C C GY T C+ + + N C+ T SFHC+C G+ G
Sbjct: 825 PQGPRCLCPTGY----TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW----TG 876
Query: 568 KNCE-DMDEC---------SIRNMCLN-GMCINEDGSFKCICKPGFQLASDGRYCKD-IN 615
C + C + ++C N G+C++ S+ C C PGFQ G C+D +N
Sbjct: 877 PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ----GSLCQDHVN 932
Query: 616 ECETPGICMNG-RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPL 674
CE+ C NG C+ Y C+C P G DG+ C
Sbjct: 933 PCESRP-CQNGATCMAQPSGYLCQCAP----GYDGQNC---------------------- 965
Query: 675 FGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDIC 734
+K C S C P P + C G D++EC LD
Sbjct: 966 ----SKELDACQSQPCHNHGTCTPKP----GGFHCACPPGFVGLRCEGDVDEC-LDQPCH 1016
Query: 735 PNG--ICENLRGTYKCICNSGYEVDSTGKNC-VDINECVLNSLLC-DNGQCRNTPGS--- 787
P G C +L + C C G+ TG+ C V+I+ C +S C G C T GS
Sbjct: 1017 PTGTAACHSLANAFYCQCLPGH----TGQWCEVEIDPC--HSQPCFHGGTCEATAGSPLG 1070
Query: 788 FVCTCPKGFIYKPDLKTCED-IDECESSPCIN-GVCKNSP 825
F+C CPKGF + TC C C + G+C SP
Sbjct: 1071 FICHCPKGF----EGPTCSHRAPSCGFHHCHHGGLCLPSP 1106
Score = 157 bits (397), Expect = 1e-37
Identities = 205/776 (26%), Positives = 283/776 (36%), Gaps = 164/776 (21%)
Query: 52 ALKGPNVC---GS------RYNAYCCPGW---KTLPGGNQCIVPICR--HSCGDGFCSRP 97
A +GP+ C GS +N C PG+ + N+C+ C +C D +
Sbjct: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH 498
Query: 98 NMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSD----DHCLCQKGYIGTHCGQPVCE-- 151
C CP G C + + + C+N C D C+C G+ GT C + + E
Sbjct: 499 --CLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECR 556
Query: 152 -SGCLNGGRCV---APNRCACTYGFTGPQCERDYR---TGPCFTVISNQ--------MCQ 196
S C NGG+C C C GF GP+C+ + + PC S +C
Sbjct: 557 SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCP 616
Query: 197 GQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGL 256
+G +C LC + + P ++C Q P+ G D C G
Sbjct: 617 SGFTGQLCEVPLCAPNLCQ----PKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGH 671
Query: 257 CQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCP 316
CQ +C+ VG +C A ++ C + P GG C S Y C CP
Sbjct: 672 CQRSSCVCDVGWTGPECEA------------ELGGCISAP-CAHGGTCYPQPSGYNCTCP 718
Query: 317 PGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQ-------LPQSITKMQC-----CCDAGR 364
G YT P T ++ + L G C+ P S T QC C +
Sbjct: 719 TG-YTGP--TCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775
Query: 365 CWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPG-----RPEYPPPPL--------GPIPP 411
C++ G V F+ LC++ P RP P P P
Sbjct: 776 CFNGGTCV-------NRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 828
Query: 412 VLPVPPGFPPG---------PQIPVPR--------PPVEYLYPS--REPPRVLPVNVTDY 452
P G+ G Q P PR P L P LP++
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 888
Query: 453 CQL-----VRYLCQN-GRCIPTPGSCRCECNKGFQLDLRGECID-VDECEKNPCA-GGEC 504
L V LC N G C+ + S C C GFQ L C D V+ CE PC G C
Sbjct: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSL---CQDHVNPCESRPCQNGATC 945
Query: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
+ Y CQC GY + +++D C Q+ N+G C G FHC C GF
Sbjct: 946 MAQPSGYLCQCAPGYDG---QNCSKELDAC-QSQPCHNHGTCTPKPGGFHCACPPGF--- 998
Query: 565 RDGKNCE-DMDECSIRNMCLNG--MCINEDGSFKCICKPGFQLASDGRYCK-DINECETP 620
G CE D+DEC + G C + +F C C PG G++C+ +I+ C +
Sbjct: 999 -VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPG----HTGQWCEVEIDPCHSQ 1053
Query: 621 GICMNGRCVNTDGS---YRCECFPGLAVGLDGRVCVDTHMRSTC--YGGYKRGQCI---K 672
G C T GS + C C G +G C +H +C + + G C+ K
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHC----PKGFEGPTC--SHRAPSCGFHHCHHGGLCLPSPK 1107
Query: 673 PLFGAVTKSECCCASTEYAFGEP-CQPCPAQNSAE------YQALCSSGPGMTSAG 721
P F C C S +G P C PA Y CS G+ G
Sbjct: 1108 PGF----PPRCACLS---GYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG 1156
Score = 94.7 bits (234), Expect = 1e-18
Identities = 84/282 (29%), Positives = 108/282 (38%), Gaps = 68/282 (24%)
Query: 2448 CNQAPKPC--NFICKNTE-GSYQCSCPKGYILQEDGRSCKDLDECATKQ-----HNCQFL 2499
C P+PC C + G C C G++ G +C+ D C Q +CQ L
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQAL 83
Query: 2500 CVNTIG----------GFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQ-NTPGSF 2548
+G F C C PGFT + C + C +G C G
Sbjct: 84 LPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPP--SFCSKRGRCHIQASGRP 141
Query: 2549 TCECQRGFSLDQTGSSCEDVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCV 2606
C C G+ TG C+ D C N C +G C +C CP G+ H C
Sbjct: 142 QCSCMPGW----TGEQCQLRDFCSANP-CVNGGVCLATYPQIQCHCPPGFEGH----ACE 192
Query: 2607 -DENECLS--AHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPC-SYG 2662
D NEC G SCHNTLGS++C+CP G Q+ C PC G
Sbjct: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----------QEGPRCELRAGPCPPRG 242
Query: 2663 CSNTEGG------------YLCGCPPGYF----RIGQGHCVS 2688
CSN GG +LC CPPG+ + +CVS
Sbjct: 243 CSN--GGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVS 282
Score = 89.0 bits (219), Expect = 6e-17
Identities = 89/306 (29%), Positives = 120/306 (39%), Gaps = 77/306 (25%)
Query: 123 CMNGGSC-----SDDHCLCQKGYIGTHCGQP-VCESG--CLNGGRCVA--------PNR- 165
C NGG+C C C G++G C P C++ C NGG C A P+
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSP 94
Query: 166 --------CACTYGFTGPQCERDYRTGPCFTVISNQM--CQGQLSGIVCTKTLCCATVGR 215
C C GFTG +C+ PC ++ C Q SG + C G
Sbjct: 95 SPLTPSFLCTCLPGFTGERCQAKLED-PCPPSFCSKRGRCHIQASG----RPQCSCMPG- 148
Query: 216 AW-GHPCEM---CPAQPHPCRRGFI-------------PNIRTGACQ-DVDECQAIPGLC 257
W G C++ C A +PC G + P AC+ DV+EC PG C
Sbjct: 149 -WTGEQCQLRDFCSA--NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205
Query: 258 -QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC----TNTVSSYF 312
+G +C NT+GSF+C CP G + +CE G GG C + +
Sbjct: 206 PKGTSCHNTLGSFQCLCPVGQE----GPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHL 261
Query: 313 CKCPPGFYTSPDGTRCIDVRPGYC--YTALTNGRCSNQL-------PQSITKMQCCCDAG 363
C CPPGF PD +V P C + G C + L P++ T C D
Sbjct: 262 CLCPPGF-IGPD----CEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVD 316
Query: 364 RCWSPG 369
C + G
Sbjct: 317 ECETQG 322
Score = 66.2 bits (160), Expect = 4e-10
Identities = 93/356 (26%), Positives = 121/356 (33%), Gaps = 90/356 (25%)
Query: 60 GSRYNAYCCPGWKTLPGGNQCIVPI--CRHSC------------GDGFC--SRPN-MCTC 102
G ++ C GW G C +P+ C+ + G C S P+ C C
Sbjct: 863 GPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHC 918
Query: 103 PSGQIAPSCGSRSIQHCNIR-CMNGGSC----SDDHCLCQKGYIGTHCGQPV--CESG-C 154
P G C + C R C NG +C S C C GY G +C + + C+S C
Sbjct: 919 PPGFQGSLCQDH-VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC 977
Query: 155 LNGGRCVAPN---RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCA 211
N G C CAC GF G +CE D C +Q C T T C
Sbjct: 978 HNHGTCTPKPGGFHCACPPGFVGLRCEGD--VDECL----DQPCHP-------TGTAACH 1024
Query: 212 TVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQ-DVDECQAIPGLCQGGNCINTVGS-- 268
++ A+ C +P C+ ++D C + P GG C T GS
Sbjct: 1025 SLANAFYCQC--------------LPGHTGQWCEVEIDPCHSQP-CFHGGTCEATAGSPL 1069
Query: 269 -FECKCPAGHKLNEVSQKCED--IDECSTIPGICEGGECTNTVSSYF---CKCPPGF--- 319
F C CP G + S + C GG C + F C C G+
Sbjct: 1070 GFICHCPKGFEGPTCSHRAPSCGFHHCH------HGGLCLPSPKPGFPPRCACLSGYGGP 1123
Query: 320 --YTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCC----DAGRCWSPG 369
T P C P L NG CS +C C RC PG
Sbjct: 1124 DCLTPPAPKGCGPPSP-----CLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPG 1174
Score = 56.6 bits (135), Expect = 3e-07
Identities = 82/356 (23%), Positives = 104/356 (29%), Gaps = 101/356 (28%)
Query: 55 GPNVCGSRYNAYCCPGWKTLPG--GNQCIVPI-------CRHSCGDGFCSRPN------M 99
G C S NA+ C + LPG G C V I C H G C +
Sbjct: 1019 GTAACHSLANAFYC---QCLPGHTGQWCEVEIDPCHSQPCFHG---GTCEATAGSPLGFI 1072
Query: 100 CTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD-------HCLCQKGYIGTHCGQPVCES 152
C CP G P+C R+ C +GG C C C GY G C P
Sbjct: 1073 CHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPK 1132
Query: 153 GCLNGGRCVAPNRCACTYGFTGP--QCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCC 210
GC C+ C+ T G GP +C C G C K
Sbjct: 1133 GCGPPSPCLYNGSCSETTGLGGPGFRCS----------------CPHSSPGPRCQK---- 1172
Query: 211 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFE 270
P +G GAC C G GG+C V
Sbjct: 1173 -------------------PGAKGCEGRSGDGACD--AGCSGPGGNWDGGDCSLGVPDPW 1211
Query: 271 CKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCID 330
CP+ +C + C+ EC Y C+ PP C
Sbjct: 1212 KGCPS-------HSRCWLLFRDGQCHPQCDSEEC--LFDGYDCETPPA---------CTP 1253
Query: 331 VRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRC--------WSPGVTVAPEMCP 378
YC+ NG C + +C D G C W P + + + P
Sbjct: 1254 AYDQYCHDHFHNGHCE----KGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSP 1305
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 295 bits (754), Expect = 6e-79
Identities = 428/1708 (25%), Positives = 573/1708 (33%), Gaps = 481/1708 (28%)
Query: 1054 RCDSGFALDSEERNCTDIDECRISPDLCGRG-QCVNTPGDFE-CKCDEGYESGFMMMKNC 1111
RC G+ +E C EC S LC G +CV PG + C C G++ C
Sbjct: 109 RCCRGWMQQPDEEGCLSA-EC--SASLCFHGGRCV--PGSAQPCHCPPGFQG-----PRC 158
Query: 1112 M-DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGR 1170
D+DEC+ C+ C NT GSY CEC PG +L + C+ IN C L C +
Sbjct: 159 QYDVDECRTHNGGCQHR-CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH-H 216
Query: 1171 CVNL-IGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1229
CV L I +++C C PG+ D CV C+ NG C C G C C G+ L
Sbjct: 217 CVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQL 276
Query: 1230 MPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVD-----VNEC 1284
D ++C D+DEC C G C N G ++C+C+ G+ D + C VN C
Sbjct: 277 AADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSC 335
Query: 1285 DLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAG 1344
+ N C G C +T +C C GY + C D+++C A + VCTN G
Sbjct: 336 EANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC---ADSPCCQQVCTNNPG 391
Query: 1345 SFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGF 1400
++C C G+ DG C D+DEC++ C H C N GS++C C+ GY D
Sbjct: 392 GYECGCYAGYRLSADGCGCEDVDECASSRGGCEHH--CTNLAGSFQCSCEAGYRLHEDRR 449
Query: 1401 TCTDLDECSENLN------------------------------------------LCGNG 1418
C+ L+E +L+ L
Sbjct: 450 GCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKF 509
Query: 1419 QCLNAPGGYRCE--CDMGFVPSADGKAC-EDIDECSLPN-----IC-------VFG---- 1459
CL+ G+ C CD +G C +D C P IC FG
Sbjct: 510 VCLDDSFGHDCSLTCD----DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCS 565
Query: 1460 ---------TCHNLPGLFRC-------ECEIGYELDRSGGNCTDVNECLDPTTC--ISGN 1501
TC ++ G RC CE G G +C C + C + G
Sbjct: 566 FSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA 625
Query: 1502 CVNTPGSY--IC--DCPPDFELNP---TRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIG 1554
C+ PG Y C CPP + P CV + +C D D +CS + G
Sbjct: 626 CLCDPGLYGRFCHLTCPP-WAFGPGCSEECQCVQPHTQSC--------DKRDGSCSCKAG 676
Query: 1555 VGVSKASCCCSLGKAWGTPC-EMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQEL 1613
+ C LG +G C + C CP G C +
Sbjct: 677 FRGERCQAECELG-YFGPGCWQAC----------TCPVGVA---------------CDSV 710
Query: 1614 PGLCQGGKCINTFGSFQC--RCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYT 1671
G C G +C F C CP G + VN C + CG C+ G
Sbjct: 711 SGEC-GKRCPAGFQGEDCGQECPVGTF---------GVN-CSSSCSCGGAPCHGVTGQ-- 757
Query: 1672 CICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNK 1731
C CPP + +C + R W
Sbjct: 758 CRCPPGRTGEDCEADCPEGR-------------------------------------WGL 780
Query: 1732 PCEQ-CPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFR 1790
C++ CP + A C D TG C +PG VGS R
Sbjct: 781 GCQEICP---ACQHAARC---------DPETG------ACLCLPG---------FVGS-R 812
Query: 1791 CE--CPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSY----RCDCKPGYR-FTS 1843
C+ CP G++ GP CQ C N + C C PG+ F+
Sbjct: 813 CQDVCPAGWY----------------GPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSC 856
Query: 1844 TGQCNDRNECQEIPNICS----HGQCIDTVGSFYCLCHTGFKTNDDQTMCLDIN---ECE 1896
C+ + + + C+ HG C D + S CLC G+ + C + CE
Sbjct: 857 QRACDTGHWGPDCSHPCNCSAGHGSC-DAI-SGLCLCEAGYVGPRCEQQCPQGHFGPGCE 914
Query: 1897 -RDACGNG-TCRNTIGSFNC-----------RCNHGFILSHNNDCIDVDECASGNGNLCR 1943
R C +G C + G+ C C GF DC C +G
Sbjct: 915 QRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFF---GLDCRSACNCTAGAACDAV 971
Query: 1944 NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP--GTCQNLDG----SYR 1997
NG C+ G +C E G C C C P G C G S
Sbjct: 972 NGSCLCPAGRRGPRCAETCPAHTYGHNCSQACAC-FNGASCDPVHGQCHCAPGWMGPSCL 1030
Query: 1998 CICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRC--QD 2055
CP G L + C C GTC G C CPEG++ + + C +D
Sbjct: 1031 QACPAG--LYGDNCRHSCLCQNG------GTCDPVSG--HCACPEGWAGLACEKECLPRD 1080
Query: 2056 LRMSYCYAK--FEGGKCSSPKSRNHSKQECCCALKGEGW-GDPCELCPTEP--DEAFRQI 2110
+R ++ GG C R C C GW GD C+ EA Q
Sbjct: 1081 VRAGCRHSGGCLNGGLCDPHTGR------CLCP---AGWTGDKCQSPCLRGWFGEACAQR 1131
Query: 2111 CPYGSGIIVGPDDSAVDMDECKEPDVCKH--GQCINTDG--SYRCE--CPFGYILAGNEC 2164
C C C H G C G CE CP G G +C
Sbjct: 1132 C------------------SCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSF--GEDC 1171
Query: 2165 VDTDECSVGNPC---GNGTCKNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLCAFR 2220
+C NP GTC G +C++ PG CE + C L
Sbjct: 1172 AQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGC-----LNGGS 1226
Query: 2221 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQ-MECKNLIGTYMCICGPG 2279
C G+ C+CP G++ + C H C Q C + GT C+C PG
Sbjct: 1227 CDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT--CLCPPG 1282
Query: 2280 YQRRPDGEGCVDENECQTKPGI-CENGRCLNTRG---SYTCECNDGFTASPNQDECLDNR 2335
+ G+ CE G N G +TC C +G
Sbjct: 1283 ------------------RAGVRCERGCPQNRFGVGCEHTCSCRNG-------------- 1310
Query: 2336 EGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGW-GPHCEICPFQGTVAFKKLCPHGR 2394
G C + C C G GW G HCE+ CP GR
Sbjct: 1311 -GLCH-----------------ASNGSCSC--GLGWTGRHCELA-----------CPPGR 1339
Query: 2395 GFMTNGADIDECKVIHD-VCR--NGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQA 2451
A EC ++ C G C G Y C+ P G C L C Q
Sbjct: 1340 ---YGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWC-QH 1395
Query: 2452 PKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKC 2511
PC+ I S +C CP G+ G C+ E + C C
Sbjct: 1396 GAPCDPI------SGRCLCPAGF----HGHFCERGCEPGSFGEGCHQRC----------- 1434
Query: 2512 PPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC--ECQRGFSLDQTGSSCEDVD 2569
C C LC +C TC +C+RG Q G SC
Sbjct: 1435 ---------DCDGGAPCDPVTGLC----LCPPGRSGATCNLDCRRG----QFGPSCTLHC 1477
Query: 2570 ECEGNHRCQHGCQNIIGGYRCSCPQGYL 2597
+C G C + + G +C C GY+
Sbjct: 1478 DCGGGADC-----DPVSG-QCHCVDGYM 1499
Score = 270 bits (690), Expect = 2e-71
Identities = 398/1602 (24%), Positives = 535/1602 (33%), Gaps = 405/1602 (25%)
Query: 999 RNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSG 1058
R P + C PGF G D++EC+ C H +C NT GS+ C C G
Sbjct: 138 RCVPGSAQPCHCPPGF------QGPRCQYDVDECRTHNGGCQH-RCVNTPGSYLCECKPG 190
Query: 1059 FALDSEERNCTDIDECRISPDLCG------------------------------RGQCVN 1088
F L ++ R C I+ C + C R C N
Sbjct: 191 FRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCAN 250
Query: 1089 TPGDF-----------ECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYR 1137
G C+C GY+ K C D+DEC C G C NT+GS++
Sbjct: 251 RNGSCMHRCQVVRGLARCECHVGYQLA-ADGKACEDVDECAAGLAQCAHG-CLNTQGSFK 308
Query: 1138 CECPPGHQLSPNISACIDI-----NECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDR 1192
C C G++L + C I N CE + C +G C + C C GY D+
Sbjct: 309 CVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQ 367
Query: 1193 LFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGG 1252
C+D+D+C+ + C+ CTN+ G YEC C G+ L D C D+DEC + C+
Sbjct: 368 RTCIDVDDCAD-SPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH- 425
Query: 1253 QCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG------------TCENTK 1300
CTN+ G ++C C G+ ED + C + E P + L G ++
Sbjct: 426 HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE----PMVDLDGELPFVRPLPHIAVLQDEL 481
Query: 1301 GSFICHCDMGYSGKKG----------KTGCTDIN---ECEIGAHNCGKHAVCTNTAGSFK 1347
D+G ++ K C D + +C + +C C G
Sbjct: 482 PQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCL--LGLDG 539
Query: 1348 CSCSPGWIG-----------DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL------ 1390
C C GW G G C+ C NG C + G+ RC
Sbjct: 540 CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG-------GTCDSVTGACRCPPGVSGT 592
Query: 1391 -----CKEGYTGDGFTCTDLDECSENLNLCGN--GQCLNAPGGYRCECDMGFVPSADGKA 1443
C +GY G C C+ N C G CL PG Y C + P A G
Sbjct: 593 NCEDGCPKGYYGKH--CRKKCNCA-NRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPG 649
Query: 1444 CEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCV 1503
C + +C P+ +C G C C+ G+ +R C
Sbjct: 650 CSEECQCVQPHT---QSCDKRDG--SCSCKAGFRGERCQAECE--------------LGY 690
Query: 1504 NTPGSY-ICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASC 1562
PG + C C P V C D+ SG C P G G+ C E VG +C
Sbjct: 691 FGPGCWQACTC-------PVGVAC-DSVSGECGKRC-PAGFQGED-CGQECPVGTFGVNC 740
Query: 1563 --CCSLGKAWGTPCE------MCPAVNTSE-YKILCPGGE-GFRPNPITVILEDIDECQE 1612
CS G G PC CP T E + CP G G I + C
Sbjct: 741 SSSCSCG---GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDP 797
Query: 1613 LPGLCQGGKCINTFGSFQCR--CPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNY 1670
G C C+ F +C+ CP G+Y C C G C P T +
Sbjct: 798 ETGAC---LCLPGFVGSRCQDVCPAGWY----GPSCQTRCSCANDGHCHPATGH------ 844
Query: 1671 TCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWN 1730
C C P + G +C + CD C CS G
Sbjct: 845 -CSCAPGWT----GFSC---------------QRACDTGHWGPDCSHPCNCSAGHG---- 880
Query: 1731 KPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFR 1790
S D + LC +CE G VG R
Sbjct: 881 ---------SCDAISGLC---------------------------LCEAG----YVGP-R 899
Query: 1791 CE--CPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCN 1848
CE CP G F CE CQ CQ A C + +G+ C C G+R T
Sbjct: 900 CEQQCPQGHFGPG----CE--QRCQ----CQHGAACDHVSGA--CTCPAGWRGTFCEHAC 947
Query: 1849 DRN----ECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMC----LDINECERDAC 1900
+C+ N C+ G D V CLC G + C N + AC
Sbjct: 948 PAGFFGLDCRSACN-CTAGAACDAVNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACAC 1005
Query: 1901 GNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASG-------NGNLCRNGQCINTVGS 1953
NG + + C C G++ C+ C +G + LC+NG + V S
Sbjct: 1006 FNGASCDPVHG-QCHCAPGWM---GPSCLQA--CPAGLYGDNCRHSCLCQNGGTCDPV-S 1058
Query: 1954 FQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDG----------SYRCICPPG 2003
C C EG+ G C ECL PR G C++ G + RC+CP G
Sbjct: 1059 GHCACPEGWA----GLACE--KECL--PRDVRAG-CRHSGGCLNGGLCDPHTGRCLCPAG 1109
Query: 2004 YSLQNEKCEDI-------DECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDL 2056
++ +KC+ + C + C + G+ C CP GF+ S + C
Sbjct: 1110 WT--GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPG 1165
Query: 2057 RMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSG 2116
A+ +C H C G G C+ Q CP G
Sbjct: 1166 SFGEDCAQM--CQCPGENPACHPATGTCSCAAGY-HGPSCQ-----------QRCPPGR- 1210
Query: 2117 IIVGPDDSAVDMDECKEPDVCKH-GQCINTDGSYRCECPFGYI-----------LAGNEC 2164
GP C++ C + G C G+ C CP G++ G C
Sbjct: 1211 --YGPG--------CEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNC 1258
Query: 2165 VDTDECSVGNPCG--NGTCKNVIGGFECTCEEGFEPGPM-MTCEDINECAQNPLLCAFRC 2221
C G C GTC G CE G + CE C L C
Sbjct: 1259 THVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL-----C 1313
Query: 2222 VNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCT-EKQMECKNLIGTYMCICGPGY 2280
+ GS C C +G+ R C +C+ C+ GT C CGPG+
Sbjct: 1314 HASNGS--CSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGT--CRCGPGF 1369
Query: 2281 QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCF 2340
G+ C E+ C PG G C C C G P CL G+
Sbjct: 1370 Y----GQAC--EHPC--PPGFHGAG-CQG-----LCWCQHGAPCDPISGRCL-CPAGF-H 1413
Query: 2341 TEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG 2400
+ C+ GS C CDGG P +C LCP GR T
Sbjct: 1414 GHFCERGCEPGSFGEG--CHQRCDCDGGAPCDPVTGLC----------LCPPGRSGATCN 1461
Query: 2401 ADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC 2442
D CR G+ + HC C G D C
Sbjct: 1462 LD----------CRRGQ-FGPSCTLHCDCGGGADCDPVSGQC 1492
Score = 267 bits (682), Expect = 1e-70
Identities = 356/1438 (24%), Positives = 484/1438 (33%), Gaps = 307/1438 (21%)
Query: 459 LC-QNGRCIPTPGSCR-CECNKGFQLDLRGEC-IDVDECEK-NPCAGGECINNQGSYTCQ 514
LC GRC+P GS + C C GFQ C DVDEC N C+N GSY C+
Sbjct: 132 LCFHGGRCVP--GSAQPCHCPPGFQ---GPRCQYDVDECRTHNGGCQHRCVNTPGSYLCE 186
Query: 515 CRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFH-CVCNAGFHVTRDGKNCEDM 573
C+ G++ C I+ C C + C+ + H C C GF + DG++C
Sbjct: 187 CKPGFRLHTDSRTCLAINSCALGNGGCQH-HCVQLTITRHRCQCRPGFQLQEDGRHCVRR 245
Query: 574 DECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETP-GICMNGRCVNTD 632
C+ RN C G +C C G+QLA+DG+ C+D++EC C +G C+NT
Sbjct: 246 SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQ 304
Query: 633 GSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAF 692
GS++C C G +G DGR C M G C S C +
Sbjct: 305 GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC----------SHGC----SHTS 350
Query: 693 GEPCQPCPAQNSAEY-QALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICN 751
P CP + Q C D+++CA P C +C N G Y+C C
Sbjct: 351 AGPLCTCPRGYELDTDQRTCI----------DVDDCADSP--CCQQVCTNNPGGYECGCY 398
Query: 752 SGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDE- 810
+GY + + G C D++EC + C++ C N GSF C+C G+ D + C ++E
Sbjct: 399 AGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEP 457
Query: 811 ----------CESSPCINGVCKNSPGSF----------ICECSSESTLDPTKTICIETIK 850
P I + P F E E TL K +C++
Sbjct: 458 MVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTL-TEKFVCLDDSF 516
Query: 851 G-----TCWQTVIDGRCEININGA------------------TLKSQCCSSLGAAWGSPC 887
G TC G C + ++G T C S G C
Sbjct: 517 GHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC 576
Query: 888 TLCQVDPICGKGYSRIKGTQCED-------IDECEVFPGVCKNGLCVNTRG--------- 931
C G + GT CED C G C G
Sbjct: 577 DSVTGACRCPPG---VSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLY 633
Query: 932 -----------------SFKCQC--PSGMTLDATGRIC---LDIRLETCFLRYEDEECTL 969
S +CQC P + D C R E C EC L
Sbjct: 634 GRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERC-----QAECEL 688
Query: 970 PIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDI 1029
G AC C VG A + EC R CP GF ++ P
Sbjct: 689 GYFGPGCWQACTCPVGVACDSVS-GECGKR--------CP--AGFQGEDCGQECPVGTFG 737
Query: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC-------- 1081
C S C C G +CRC G + E +C + ++C
Sbjct: 738 VNCSSSCS-CGGAPCHGVTG--QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAAR 794
Query: 1082 ---GRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRC 1138
G C+ PG +C + +G+ +C C D G CH G C
Sbjct: 795 CDPETGACLCLPGFVGSRCQDVCPAGW-YGPSCQTRCSCAND------GHCHPATG--HC 845
Query: 1139 ECPPGHQLSPNISACIDINECELSAHLC----PNGRCVNLIGKYQCACNPGY-------- 1186
C PG AC + +H C +G C + G C C GY
Sbjct: 846 SCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQ 903
Query: 1187 ----HSTP---DRLFCVDIDECSIMNGGCE-------TFCTNS--------EGSYECSCQ 1224
H P R C C ++G C TFC ++ + C+C
Sbjct: 904 CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCT 963
Query: 1225 PGFALMPDQRSC------------------TDIDECEDNPNICDGGQCTNIPGEYRCLCY 1266
G A SC T C +G C + G+ C C
Sbjct: 964 AGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQ--CHCA 1021
Query: 1267 DGFMASEDMKTCVDVNECDLNPNICL---SGTCENTKGSFICHCDMGYSGKKGKTGC--T 1321
G+M ++ C D + CL GTC+ G C C G++G + C
Sbjct: 1022 PGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGH--CACPEGWAGLACEKECLPR 1079
Query: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNG--THMCSQHAD 1379
D+ + C +C G +C C GW GD KC C G C+Q
Sbjct: 1080 DVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGD--KCQ--SPCLRGWFGEACAQRCS 1133
Query: 1380 CKNTMGSYR----CLCKEGYTGDGF-----------TCTDLDECSENLNLC--GNGQCLN 1422
C + C C G+TG G C + +C C G C
Sbjct: 1134 CPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSC 1193
Query: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNIC--VFGTCHNLPGLFRCECEIGYELDR 1480
A G + C P G CE + C C G C G +C + R
Sbjct: 1194 AAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGR 1253
Query: 1481 SGGNCTDVNECLDPTTC--ISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRS----GNC 1534
G NCT V C C ++G C+ PG C N VGC T S G C
Sbjct: 1254 FGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLC 1313
Query: 1535 YLDIRPRGDNGDTACSNEIGVGVSKASC--CCSLGKAWGTPCEM-CPAVNTSEYKI---L 1588
+ NG +C G+G + C C G+ +G C + C N S +
Sbjct: 1314 H------ASNGSCSC----GLGWTGRHCELACPPGR-YGAACHLECSCHNNSTCEPATGT 1362
Query: 1589 CPGGEGFR----PNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTR 1644
C G GF +P CQ L G C G +C CP G++ + R
Sbjct: 1363 CRCGPGFYGQACEHPCPPGFHGAG-CQGLCWCQHGAPCDPISG--RCLCPAGFHGHFCER 1419
Query: 1645 VCDDVN---------ECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNC-MDMRR 1692
C+ + +C+ C P T C+CPP G C +D RR
Sbjct: 1420 GCEPGSFGEGCHQRCDCDGGAPCDPVT-------GLCLCPPG----RSGATCNLDCRR 1466
Score = 264 bits (675), Expect = 8e-70
Identities = 378/1542 (24%), Positives = 525/1542 (34%), Gaps = 333/1542 (21%)
Query: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDG 1358
T+ + C G+ + + GC E A C C + C C PG+ G
Sbjct: 102 TEARTVLRCCRGWMQQPDEEGCLS---AECSASLCFHGGRCVPGSAQ-PCHCPPGF--QG 155
Query: 1359 IKCT-DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSENLNLC 1415
+C D+DEC C QH C NT GSY C CK G+ D TC ++ C+
Sbjct: 156 PRCQYDVDECRTHNGGC-QHR-CVNTPGSYLCECKPGFRLHTDSRTCLAINSCA-----L 208
Query: 1416 GNGQCLN-----APGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRC 1470
GNG C + +RC+C GF DG+ C C+ N C + GL RC
Sbjct: 209 GNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARC 268
Query: 1471 ECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTR 1530
EC +GY+L G C DV+EC + C+NT GS+ C C +EL D R
Sbjct: 269 ECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELG------ADGR 322
Query: 1531 SGNCY---LDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKI 1587
CY ++I + + CS+ G + A C+
Sbjct: 323 --QCYRIEMEIVNSCEANNGGCSH--GCSHTSAGPLCT---------------------- 356
Query: 1588 LCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCD 1647
CP G + T I D+D+C + P C C N G ++C C GY L+ D C+
Sbjct: 357 -CPRGYELDTDQRTCI--DVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCE 411
Query: 1648 DVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCD 1707
DV+EC + C N G++ C C Y C + + D
Sbjct: 412 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMV---------DLD 462
Query: 1708 GELLF-NMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQ--RPGFV-IDIYTG- 1762
GEL F + + + + + + + +E A L G FV +D G
Sbjct: 463 GELPFVRPLPHIAVLQDELPQLF----QDDDVGADEEEAELRGEHTLTEKFVCLDDSFGH 518
Query: 1763 -LPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDI-------DECQN 1814
+ D+CR G C ++G C+CP G+ L+C + C
Sbjct: 519 DCSLTCDDCR------NGGTC--LLGLDGCDCPEGW----TGLICNETCPPDTFGKNCSF 566
Query: 1815 GPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCND-------RNECQEIPNICSHGQCID 1867
CQ C + G+ C C PG T+ C D C++ N + G+C
Sbjct: 567 SCSCQNGGTCDSVTGA--CRCPPGVSGTN---CEDGCPKGYYGKHCRKKCNCANRGRCHR 621
Query: 1868 TVGSFYCLCHTGFKTNDDQTMCLD-------INECERDACGNGTCRNTIGSFNCRCNHGF 1920
G+ CLC G C EC+ +C GS C C GF
Sbjct: 622 LYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGF 677
Query: 1921 ILSHNNDCIDVDECASGNGNLCR---NGQCINTVGSFQCQCNEGYEVAPDGRTCV--DIN 1975
++ G C C + G +C G++ G+ C
Sbjct: 678 RGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFG 737
Query: 1976 ECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEE------PEICA---- 2025
C C + G +C CPPG + E CE +C E EIC
Sbjct: 738 VNCSSSCSCGGAPCHGVTG--QCRCPPGRT--GEDCE--ADCPEGRWGLGCQEICPACQH 791
Query: 2026 LGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC 2085
C G+ CLC GF G RCQD+ C A + G C + C C
Sbjct: 792 AARCDPETGA--CLCLPGF----VGSRCQDV----CPAGWYGPSCQT---------RCSC 832
Query: 2086 ALKGEGWGDP----CELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCK--H 2139
A +G P C P + ++ C G GPD C P C H
Sbjct: 833 A--NDGHCHPATGHCSCAPGWTGFSCQRACDTGHW---GPD--------CSHPCNCSAGH 879
Query: 2140 GQCINTDGSYRCE-----------CPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGF 2188
G C G CE CP G+ G C +C G C +V G
Sbjct: 880 GSCDAISGLCLCEAGYVGPRCEQQCPQGHF--GPGCEQRCQCQHG-----AACDHVSGA- 931
Query: 2189 ECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSY------ECKCPVGYVLREDR 2242
CTC G+ CE L C C T G+ C CP G R
Sbjct: 932 -CTCPAGWRG---TFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAG---RRGP 984
Query: 2243 RMCKDEDECEEGKHDCTE-----KQMECKNLIGTYMCICGPGYQRRPDGEGC---VDENE 2294
R C + H+C++ C + G C C PG+ + C + +
Sbjct: 985 R-CAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDN 1041
Query: 2295 CQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDN-------------REGYCFT 2341
C+ +C+NG + + C C +G+ + ECL G C
Sbjct: 1042 CR-HSCLCQNGGTCDPVSGH-CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDP 1099
Query: 2342 EVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA 2401
+ +C G T +C RGW F A + CP G
Sbjct: 1100 HTGRCLCPAG------WTGDKCQSPCLRGW--------FGEACAQRCSCPPGAA------ 1139
Query: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKN 2461
C + CR G C+ P G C + +C C+
Sbjct: 1140 ----CHHVTGACRCPPGFTGSG-----CEQACPPGSFGEDCAQMCQCPGENPACH----- 1185
Query: 2462 TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGF------TCKCPPGF 2515
+ CSC GY G SC+ C+ LC GG C+CP GF
Sbjct: 1186 -PATGTCSCAAGY----HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGF 1240
Query: 2516 --TQHHTSCIDNNECTSDINLCGS---------KGICQNTPGSFTCECQRGFSLDQTGSS 2564
T + +C + ++CG G C PG C+RG ++ G
Sbjct: 1241 LGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVG 1300
Query: 2565 CEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHN 2624
CE C C CSC G+ + C + H+ SCHN
Sbjct: 1301 CEHTCSCRNGGLCH------ASNGSCSCGLGWTGRHCELACPPGRYGAACHL--ECSCHN 1352
Query: 2625 ------TLGSYKC-----------MCPAGFQYEQFSGGCQDINEC--GSAQAPCSYGCSN 2665
G+ +C CP GF GCQ + C G+ P S C
Sbjct: 1353 NSTCEPATGTCRCGPGFYGQACEHPCPPGFH----GAGCQGLCWCQHGAPCDPISGRCLC 1408
Query: 2666 TEG--GYLC--GCPPGYFRIGQGHCVSGMGMGRGNPEPPVSG 2703
G G+ C GC PG F G+G C G P PV+G
Sbjct: 1409 PAGFHGHFCERGCEPGSF--GEG-CHQRCDCDGGAPCDPVTG 1447
Score = 254 bits (649), Expect = 9e-67
Identities = 369/1556 (23%), Positives = 523/1556 (33%), Gaps = 335/1556 (21%)
Query: 148 PVCESGCLNGGRCVAPNRCACTY-GFTGPQCERDYRTGPCFTVISNQMCQG---QLSGIV 203
PV ++GC CV R Y G+ R T TV+ + C+G Q
Sbjct: 71 PVWKAGCGWQAWCVGHERRTVYYMGY------RQVYTTEARTVL--RCCRGWMQQPDEEG 122
Query: 204 CTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQ-DVDECQAIPGLCQGGNC 262
C C A++ G C AQP C GF + CQ DVDEC+ G CQ C
Sbjct: 123 CLSAECSASLCFHGGR-CVPGSAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQH-RC 176
Query: 263 INTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTS 322
+NT GS+ C+C G +L+ S+ C I+ C+ G C+ T++ + C+C PGF
Sbjct: 177 VNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQ 236
Query: 323 PDGTRCIDVRPGYCYTALTNGRCSN--QLPQSITKMQC------------CCDAGRCWSP 368
DG C+ P A NG C + Q+ + + + +C C D C +
Sbjct: 237 EDGRHCVRRSP----CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-AA 291
Query: 369 GVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVP 428
G+ C + F +C G+ G
Sbjct: 292 GLAQCAHGC-LNTQGSFKCVCHA--------------------------GYELGAD---- 320
Query: 429 RPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDL-RGE 487
R+ R+ + + + C+ C +G C T C C +G++LD +
Sbjct: 321 ---------GRQCYRI-EMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRT 369
Query: 488 CIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCI 547
CIDVD+C +PC C NN G Y C C AGY+ + C D+DEC + C + C
Sbjct: 370 CIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCT 428
Query: 548 NTDGSFHCVCNAGFHVTRDGKNCE------------------------------------ 571
N GSF C C AG+ + D + C
Sbjct: 429 NLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDD 488
Query: 572 ----DMDECSIR-NMCLNGMCINEDGSFKCICKPGFQLASDGRYC-KDINECETP----G 621
D +E +R L + D SF C +G C ++ C+ P G
Sbjct: 489 DVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTG 548
Query: 622 ICMNGRC----VNTDGSYRCECFPG-----------LAVGLDGRVCVD--------THMR 658
+ N C + S+ C C G G+ G C D H R
Sbjct: 549 LICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCR 608
Query: 659 STCYGGYKRGQCIKPLFGAVTKSE------CCCASTEYAFGEPCQPCPAQNSAEYQALCS 712
C RG+C + L+GA C +AFG C Q + C
Sbjct: 609 KKC-NCANRGRCHR-LYGACLCDPGLYGRFCHLTCPPWAFGPGCSE-ECQCVQPHTQSCD 665
Query: 713 SGPGMTS--AGSDINECALDPDI------------CPNGI-CENLRGTYKCICNSGYEVD 757
G S AG C + ++ CP G+ C+++ G C +G++ +
Sbjct: 666 KRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGE 725
Query: 758 STGKNCV--DINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP 815
G+ C +S C C G C CP G +T ED CE+
Sbjct: 726 DCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQ--CRCPPG-------RTGED---CEAD- 772
Query: 816 CINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 875
C G C + DP C+ C + RC+ C
Sbjct: 773 CPEGRWGLGCQEICPACQHAARCDPETGACL------CLPGFVGSRCQDVCPAGWYGPSC 826
Query: 876 CSSLGAAWGSPCTLCQVDPICGKGYSRIK----------GTQCEDIDECEVFPGVCK--N 923
+ A C C G++ G C C G C +
Sbjct: 827 QTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAIS 886
Query: 924 GLCVNTRG-------------------SFKCQCPSGMTLDATGRICLDIRLETCFLRYE- 963
GLC+ G +CQC G D C TC +
Sbjct: 887 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGAC------TCPAGWRG 940
Query: 964 ---DEECTLPIAGRHRMDACCCSVGAAWGTEECE-ECPM-RNTPEYEELCPRGPGFATKE 1018
+ C G AC C+ GAA CP R P E CP
Sbjct: 941 TFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAH------- 993
Query: 1019 ITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD---IDECR 1075
T G + C + C G +C C G+ S + C D CR
Sbjct: 994 -TYG-------HNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNCR 1043
Query: 1076 ISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDID---ECQRDPLLCRGGVCHNT 1132
S G C P C C EG+ +G K C+ D C+ GG+C
Sbjct: 1044 HSCLCQNGGTC--DPVSGHCACPEGW-AGLACEKECLPRDVRAGCRHSGGCLNGGLCDPH 1100
Query: 1133 EGSYRCECPPGHQLSPNISACIDINECELSAHLC---PNGRCVNLIGKYQCACNPGY--- 1186
G RC CP G S C+ E A C P C ++ G C C PG+
Sbjct: 1101 TG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTG--ACRCPPGFTGS 1156
Query: 1187 ---HSTPDRLF---CVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTD-- 1238
+ P F C + +C N C + CSC G+ Q+ C
Sbjct: 1157 GCEQACPPGSFGEDCAQMCQCPGENPACH------PATGTCSCAAGYHGPSCQQRCPPGR 1210
Query: 1239 -IDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG--- 1294
CE +GG C G C C GF+ ++ TC ++C G
Sbjct: 1211 YGPGCEQLCGCLNGGSCDAATG--ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGA 1268
Query: 1295 TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAH---NCGKHAVCTNTAGSFKCSCS 1351
C+ G+ C C G +G + + GC N +G +C +C + GS CSC
Sbjct: 1269 ACDPVTGT--CLCPPGRAGVRCERGCPQ-NRFGVGCEHTCSCRNGGLCHASNGS--CSCG 1323
Query: 1352 PGWIGDGIKCTDLDECSNGTH--------MCSQHADCKNTMGSYRC-----------LCK 1392
GW G + C G + C ++ C+ G+ RC C
Sbjct: 1324 LGWTGRHCELA----CPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCP 1379
Query: 1393 EGYTGDGFTCTDLDECSENLNLCG--NGQCLNAPGGYRCECDMGFVPSADGKACEDIDEC 1450
G+ G G C L C C +G+CL G + C+ G P + G+ C +C
Sbjct: 1380 PGFHGAG--CQGLCWCQHGAP-CDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDC 1436
Query: 1451 SLPNIC--VFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTC--ISGNC 1502
C V G C PG C + + G +CT +C C +SG C
Sbjct: 1437 DGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQC 1492
Score = 234 bits (598), Expect = 7e-61
Identities = 362/1442 (25%), Positives = 495/1442 (34%), Gaps = 301/1442 (20%)
Query: 748 CICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806
C C G++ G C D++EC ++ C + +C NTPGS++C C GF D +TC
Sbjct: 147 CHCPPGFQ----GPRCQYDVDECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCL 201
Query: 807 DIDECESSPCINGVCKNSPGSFI-----CECSSESTLDPTKTICIETIKGTCWQTVIDGR 861
I+ C NG C++ C+C L C+ + C
Sbjct: 202 AINSCALG---NGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVR--RSPC-------- 248
Query: 862 CEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYS-RIKGTQCEDIDECEVFPGV 920
N NG+ + +C G A C+ C GY G CED+DEC
Sbjct: 249 --ANRNGSCMH-RCQVVRGLA------RCE----CHVGYQLAADGKACEDVDECAAGLAQ 295
Query: 921 CKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDAC 980
C +G C+NT+GSFKC C +G L A GR C I +E C G
Sbjct: 296 CAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIV------NSCEANNGG------- 341
Query: 981 CCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCT 1040
CS G + T C CPRG T + T D+++C P C
Sbjct: 342 -CSHGCSH-TSAGPLCT----------CPRGYELDTDQRT-----CIDVDDCADSP--CC 382
Query: 1041 HGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEG 1100
C N G ++C C +G+ L ++ C D+DEC S C C N G F+C C+ G
Sbjct: 383 QQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQCSCEAG 441
Query: 1101 YESGFMMMKNCMDIDECQRD---------------------PLLCRGGVCHNTEGSYRCE 1139
Y + C ++E D P L + E E
Sbjct: 442 YRL-HEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADE--EEAE 498
Query: 1140 CPPGHQLSPNISACIDI---NECELSAHLCPNGRCVNLIGKYQCACNPGY------HSTP 1190
H L+ C+D ++C L+ C NG L+G C C G+ + P
Sbjct: 499 LRGEHTLTEKF-VCLDDSFGHDCSLTCDDCRNGGTC-LLGLDGCDCPEGWTGLICNETCP 556
Query: 1191 DRLFCVDID-ECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTD---IDECEDNP 1246
F + CS NGG C + G+ C C PG + + C C
Sbjct: 557 PDTFGKNCSFSCSCQNGGT---CDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKC 611
Query: 1247 NICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVD-------VNECD-LNPNICLSGTCEN 1298
N + G+C + G CLC G TC EC + P+ + +C+
Sbjct: 612 NCANRGRCHRLYG--ACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH---TQSCDK 666
Query: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIG--------AHNCGKHAVCTNTAGSFKCSC 1350
GS C C G+ G++ + ECE+G A C C + +G C
Sbjct: 667 RDGS--CSCKAGFRGERCQA------ECELGYFGPGCWQACTCPVGVACDSVSGECGKRC 718
Query: 1351 SPGWIGD--GIKCTDLDECSNGTHMCS-QHADCKNTMGSYRCLCKEGYTGD--------- 1398
G+ G+ G +C N + CS A C G +C C G TG+
Sbjct: 719 PAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPPGRTGEDCEADCPEG 776
Query: 1399 --GFTCTDLDECSENLNLCG--NGQCLNAPG--GYRCE--CDMGFVPSADGKACEDIDEC 1450
G C ++ ++ C G CL PG G RC+ C G+ G +C+ C
Sbjct: 777 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWY----GPSCQTRCSC 832
Query: 1451 SLPNIC--VFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECL---DPTTCISGNCVNT 1505
+ C G C PG C+ + G +C+ C ISG C+
Sbjct: 833 ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCE 892
Query: 1506 PGSYICDCPPDFELNPTRVGC-----------VDTRSGNCYLDIRPRGDNGDTACSNEIG 1554
G C GC D SG C RG + AC
Sbjct: 893 AGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFF 952
Query: 1555 VGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGG-EGFRPNPITVILEDIDECQEL 1613
+++C C+ G A C AVN S LCP G G R C +
Sbjct: 953 GLDCRSACNCTAGAA-------CDAVNGS---CLCPAGRRGPRCAETCPAHTYGHNCSQA 1002
Query: 1614 PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDD---VNECETPGIC-GPGTCYNTVGN 1669
G C G QC C G+ + C + C +C GTC G+
Sbjct: 1003 CACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGH 1060
Query: 1670 YTCICPPDYMQVNGGNNCM--DMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGR 1727
C CP + + C+ D+R + + CD T + C + G
Sbjct: 1061 --CACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPH-----TGRCLCPAGWTGD 1113
Query: 1728 AWNKPCEQCPIPSTDEFATLCG---SQRPGFVIDIYTGLPVDIDECREIPGVCENGVCIN 1784
PC + F C S PG TG CR PG +G
Sbjct: 1114 KCQSPCLR------GWFGEACAQRCSCPPGAACHHVTG------ACRCPPGFTGSG---- 1157
Query: 1785 MVGSFRCE--CPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFT 1842
CE CP G F D C + +C N C G+ C C GY
Sbjct: 1158 ------CEQACPPGSFGED----CAQMCQCPG-----ENPACHPATGT--CSCAAGYHGP 1200
Query: 1843 STGQCNDR-------NECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMC----LD 1891
S C R C+++ + G C G+ C C TGF D C
Sbjct: 1201 S---CQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFG 1255
Query: 1892 INECERDACG--------NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDE-CASGNGNLC 1942
N CG GTC G RC G N + + C+ NG LC
Sbjct: 1256 PNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERG--CPQNRFGVGCEHTCSCRNGGLC 1313
Query: 1943 R--NGQCINTVG----SFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSY 1996
NG C +G + C G A C N EP A GTC+ G Y
Sbjct: 1314 HASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEP---ATGTCRCGPGFY 1370
Query: 1997 ----RCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRR 2052
CPPG+ C+ + C C G +CLCP GF R
Sbjct: 1371 GQACEHPCPPGF--HGAGCQGLCWCQHG------APCDPISG--RCLCPAGFHGHFCERG 1420
Query: 2053 CQ 2054
C+
Sbjct: 1421 CE 1422
Score = 108 bits (271), Expect = 6e-23
Identities = 181/743 (24%), Positives = 234/743 (31%), Gaps = 153/743 (20%)
Query: 56 PNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCG---DGFCS-RPNMCTCPSGQIAPSC 111
P GSR C GW P C+ C DG C C+C G SC
Sbjct: 806 PGFVGSRCQDVCPAGWYG---------PSCQTRCSCANDGHCHPATGHCSCAPGWTGFSC 856
Query: 112 GSR-SIQHCNIRCMNGGSCSDDH---------CLCQKGYIGTHCGQ--------PVCES- 152
H C + +CS H CLC+ GY+G C Q P CE
Sbjct: 857 QRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR 916
Query: 153 -GCLNGGRC-VAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVC--TKTL 208
C +G C C C G+ G CE G F + + +G C
Sbjct: 917 CQCQHGAACDHVSGACTCPAGWRGTFCEHACPAG--FFGLDCRSACNCTAGAACDAVNGS 974
Query: 209 CCATVGRAWGHPCEMCPAQP--HPCRRGFIPNIRTGACQDVDECQAIPGLC------QGG 260
C GR E CPA H C + AC + C + G C G
Sbjct: 975 CLCPAGRRGPRCAETCPAHTYGHNCSQAC-------ACFNGASCDPVHGQCHCAPGWMGP 1027
Query: 261 NCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFY 320
+C+ CPAG + C +C+ G + VS + C CP G+
Sbjct: 1028 SCLQA-------CPAGLYGDNCRHSC-----------LCQNGGTCDPVSGH-CACPEGWA 1068
Query: 321 TSPDGTRCI--DVRPGYCYT--ALTNGRCSNQLPQSITKMQCCCDAG----RCWSPGV-- 370
C+ DVR G ++ L G C +C C AG +C SP +
Sbjct: 1069 GLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG------RCLCPAGWTGDKCQSPCLRG 1122
Query: 371 ---TVAPEMC---PIRATEDFNKLCSVPMVIPG---RPEYPPPPLGPIPPVLPVPPGFPP 421
+ C P A C P G PP G + PG P
Sbjct: 1123 WFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENP 1182
Query: 422 G--PQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRC----- 474
P Y PS + R P C+ + G C G+CRC
Sbjct: 1183 ACHPATGTCSCAAGYHGPSCQ-QRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL 1241
Query: 475 --ECNKGFQLDLRG-ECIDVDECEKNPCAG---GECINNQGSYTCQCRAGYQSTLTRTEC 528
+CN G C V C + G C+ G +C G C
Sbjct: 1242 GTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGC 1301
Query: 529 RDIDECLQNGRIC--NNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM 586
C +NG +C +NG C G C R G C ECS N N
Sbjct: 1302 EHTCSC-RNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACH--LECSCHN---NST 1355
Query: 587 CINEDGSFKC-----------ICKPGFQLASDGRYCKDINECETPGIC--MNGRCVNTDG 633
C G+ +C C PGF G C+ + C+ C ++GRC+ G
Sbjct: 1356 CEPATGTCRCGPGFYGQACEHPCPPGFH----GAGCQGLCWCQHGAPCDPISGRCLCPAG 1411
Query: 634 SYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYK----RGQCIKP--LFGAVTKSEC---- 683
+ C G G G C H R C GG G C+ P GA +C
Sbjct: 1412 FHGHFCERGCEPGSFGEGC---HQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQ 1468
Query: 684 ----CCASTEYAFGEPCQPCPAQ 702
C + G C P Q
Sbjct: 1469 FGPSCTLHCDCGGGADCDPVSGQ 1491
Score = 105 bits (261), Expect = 8e-22
Identities = 228/1010 (22%), Positives = 317/1010 (31%), Gaps = 216/1010 (21%)
Query: 439 REPPRVLPVNVTDYCQLVRY--------LCQN-GRCIPTPGSCRCE-------CNKGFQL 482
R PP V N D C Y C N GRC G+C C+ C+
Sbjct: 584 RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPP 643
Query: 483 DLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECR---DIDECLQNGR 539
G +EC+ C GS C C+AG++ + EC C Q
Sbjct: 644 WAFGPGCS-EECQCVQPHTQSCDKRDGS--CSCKAGFRGERCQAECELGYFGPGCWQACT 700
Query: 540 ICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMD---ECSIRNMCLNGMCINEDGSFKC 596
C + G C AGF G+ C CS C C G +C
Sbjct: 701 CPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QC 758
Query: 597 ICKPGFQLASDGRYCKDINECETP----GICMNGRCVNTDGSYRCECFPGLAVGLDGRVC 652
C PG G C E + P G+ C + RC+ G + L G
Sbjct: 759 RCPPG----RTGEDC----EADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPG--F 808
Query: 653 VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEY---AFGEPCQPCPAQNSAEYQA 709
V + + C G+ +G ++ C CA+ + A G C P Q
Sbjct: 809 VGSRCQDVCPAGW---------YGPSCQTRCSCANDGHCHPATGH-CSCAPGWTGFSCQR 858
Query: 710 LCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD--IN 767
C +G N C+ +G C+ + G C+C +GY + C
Sbjct: 859 ACDTGHWGPDCSHPCN-CS-----AGHGSCDAISGL--CLCEAGYVGPRCEQQCPQGHFG 910
Query: 768 ECVLNSLLCDNG-QCRNTPGSFVCTCPKGF------------IYKPDLKTCEDIDECESS 814
C +G C + G+ CTCP G+ + D ++ + +
Sbjct: 911 PGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC 968
Query: 815 PCINGVCKNSPG-------------------SFICECSSESTLDPTKTICIETIKGTCWQ 855
+NG C G S C C + ++ DP C G
Sbjct: 969 DAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQC-HCAPGWMGP 1027
Query: 856 TVIDGRCEININGATLKSQC-CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE----- 909
+ + C + G + C C + G C C +G++ G CE
Sbjct: 1028 SCLQA-CPAGLYGDNCRHSCLCQN-----GGTCDPVSGHCACPEGWA---GLACEKECLP 1078
Query: 910 -DIDE-CEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRL-ETCFLRYEDEE 966
D+ C G GLC G +C CP+G T D CL E C R
Sbjct: 1079 RDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEACAQRC---S 1133
Query: 967 CTLPIAGRHRMDACCCSVG------------AAWGTEECE---ECPMRNTPEYEE--LCP 1009
C A H AC C G ++G E+C +CP N + C
Sbjct: 1134 CPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFG-EDCAQMCQCPGENPACHPATGTCS 1192
Query: 1010 RGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCT 1069
G+ P + C+ + G C G+ CRC +GF C
Sbjct: 1193 CAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTC- 1249
Query: 1070 DIDECRISPD---LCGRGQ----------CVNTPGDFECKCDEGYESGFMMMKNCMDIDE 1116
+ R P+ +CG GQ C+ PG +C+ G + C
Sbjct: 1250 --PQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGV-GCEHTCS 1306
Query: 1117 CQRDPLLCRGGVCHNTEGSYRC-----------ECPPGHQLSPNISACIDINECELSAHL 1165
C+ GG+CH + GS C CPPG + C L
Sbjct: 1307 CR------NGGLCHASNGSCSCGLGWTGRHCELACPPGRYGA----------ACHLECSC 1350
Query: 1166 CPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEG------SY 1219
N C G C C PG++ C GC+ C G S
Sbjct: 1351 HNNSTCEPATG--TCRCGPGFYGQA----CEHPCPPGFHGAGCQGLCWCQHGAPCDPISG 1404
Query: 1220 ECSCQPGFALMPDQRSCTDIDECEDNPNICD---GGQCTNIPGEYRCLCYDGFMASEDMK 1276
C C GF +R C E CD G C + G CLC G +
Sbjct: 1405 RCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTG--LCLCPPGRSGA---- 1458
Query: 1277 TC-VDVNECDLNPNICL------SGTCENTKGSFICHCDMGYSGKKGKTG 1319
TC +D P+ L C+ G CHC GY G + G
Sbjct: 1459 TCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ--CHCVDGYMGPTCREG 1506
Score = 82.8 bits (203), Expect = 4e-15
Identities = 74/275 (26%), Positives = 98/275 (35%), Gaps = 53/275 (19%)
Query: 61 SRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCN 120
+R+ C PG++ G C+ R C + S + C G C H
Sbjct: 223 TRHRCQCRPGFQLQEDGRHCVR---RSPCANRNGSCMHRCQVVRGLARCEC------HVG 273
Query: 121 IR-CMNGGSCSD-DHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFT----G 174
+ +G +C D D C G C GCLN +C C G+ G
Sbjct: 274 YQLAADGKACEDVDECAA---------GLAQCAHGCLN---TQGSFKCVCHAGYELGADG 321
Query: 175 PQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH-PCRR 233
QC R I C H C A P C R
Sbjct: 322 RQCYR----------------------IEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPR 359
Query: 234 GFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECS 293
G+ + C DVD+C P C C N G +EC C AG++L+ CED+DEC+
Sbjct: 360 GYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA 417
Query: 294 TIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 328
+ G CE CTN S+ C C G+ D C
Sbjct: 418 SSRGGCE-HHCTNLAGSFQCSCEAGYRLHEDRRGC 451
Score = 70.5 bits (171), Expect = 2e-11
Identities = 90/352 (25%), Positives = 110/352 (31%), Gaps = 76/352 (21%)
Query: 67 CCPGWKTLPGGNQCIVPI----CRHSCG---DGFC-SRPNMCTCPSGQIAPSC------- 111
C GW L C C SC G C S C CP G +C
Sbjct: 542 CPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKG 601
Query: 112 --GSRSIQHCNIRCMNGGSCSDDH--CLCQKGYIGTHCGQPVCES-----GCLNGGRCVA 162
G + CN C N G C + CLC G G C C GC +CV
Sbjct: 602 YYGKHCRKKCN--CANRGRCHRLYGACLCDPGLYGRFC-HLTCPPWAFGPGCSEECQCVQ 658
Query: 163 PNR---------CACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATV 213
P+ C+C GF G +C+ + G G C + C +V
Sbjct: 659 PHTQSCDKRDGSCSCKAGFRGERCQAECELG--------YFGPGCWQACTCPVGVACDSV 710
Query: 214 GRAWGHPCEMCPA--QPHPCRRGFIPNIRTGACQDVDECQAIPGLCQG--GNCINTVG-- 267
G + CPA Q C + C C P C G G C G
Sbjct: 711 SGECG---KRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAP--CHGVTGQCRCPPGRT 765
Query: 268 --SFECKCPAGH---KLNEVSQKCEDIDECSTIPGIC------EGGECTNTVSSYFCKCP 316
E CP G E+ C+ C G C G C + CP
Sbjct: 766 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV-------CP 818
Query: 317 PGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSP 368
G+Y TRC G+C+ A G CS + Q CD G W P
Sbjct: 819 AGWYGPSCQTRCSCANDGHCHPA--TGHCSCAPGWTGFSCQRACDTGH-WGP 867
Score = 39.7 bits (91), Expect = 0.043
Identities = 42/158 (26%), Positives = 47/158 (29%), Gaps = 41/158 (25%)
Query: 59 CGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGF----------CSR-------PNMCT 101
C N+ C P T G C H C GF C C
Sbjct: 1348 CSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCL 1407
Query: 102 CPSGQIAPSC---------GSRSIQHCNIRCMNGGSCSD--DHCLCQKGYIGTHC----- 145
CP+G C G Q C+ C G C CLC G G C
Sbjct: 1408 CPAGFHGHFCERGCEPGSFGEGCHQRCD--CDGGAPCDPVTGLCLCPPGRSGATCNLDCR 1465
Query: 146 -GQ--PVCESGCLNGGRC---VAPNRCACTYGFTGPQC 177
GQ P C C GG +C C G+ GP C
Sbjct: 1466 RGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTC 1503
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 291 bits (746), Expect = 5e-78
Identities = 179/509 (35%), Positives = 246/509 (48%), Gaps = 59/509 (11%)
Query: 1018 EITNGKPFFKDINECKMIPS-LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRI 1076
E+ N P D +EC ++P LC H C NT+GS+ C C GF+L + R C
Sbjct: 595 ELPNSLPG-DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGH--- 649
Query: 1077 SPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSY 1136
P Q +F C D C++ VC GS
Sbjct: 650 -PPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ--------VCSTVGGSA 700
Query: 1137 RCECPPGHQLSPNISACIDINECELSAHLCPNGR-CVNLIGKYQC----ACNPGYHSTPD 1191
C C PG+ + + +C DINEC H C G CVN +G + C C PGY
Sbjct: 701 ICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG 760
Query: 1192 RLFCVDIDECSIMNGGCET--FCTNSEGSYECS----CQPGFALMPDQRSCTDIDECEDN 1245
C D+DEC++ C+ C N++GS+ C C GF L + +C DI+EC
Sbjct: 761 E--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSL 817
Query: 1246 PNICDGG-QCTNIPGEYRC-----LCYDGFMASEDMKTCVDVNECDLNPNICLSG-TCEN 1298
C G C N G Y C +C G+ AS+D CVDVNEC+ + C G C N
Sbjct: 818 SEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN 877
Query: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--G 1356
GS+ C C G+ GC D+NEC +H C NT GS++CSC+ G++
Sbjct: 878 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT-CENTLGSYRCSCASGFLLAA 936
Query: 1357 DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLNL 1414
DG +C D++EC CSQ +C N GSY+C C++GY DG TCTD+DEC++ +
Sbjct: 937 DGKRCEDVNECE--AQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGI 992
Query: 1415 CGNGQCLNAPGGYRCEC-DMGFVPSADGKACEDIDECSL--PNICVFGTCHNLPGLFRC- 1470
+CLN PG Y+C C + G+ +A+G++C+D+DEC+L N TCHN+ G FRC
Sbjct: 993 LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1052
Query: 1471 --ECEIGY------ELDRSGGNCTDVNEC 1491
EC Y + +R+ C D EC
Sbjct: 1053 RFECPPNYVQVSKTKCERT--TCHDFLEC 1079
Score = 252 bits (644), Expect = 3e-66
Identities = 185/603 (30%), Positives = 248/603 (41%), Gaps = 106/603 (17%)
Query: 981 CCSVGAAWG--TEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSL 1038
CC+ G W +EC E P T + N C+
Sbjct: 445 CCAAGQQWAIDNDECLEIPESGTED--------------------------NVCRTAQRH 478
Query: 1039 CTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISP-----DLCGRGQCVNTPGDF 1093
C C + + C A + E D D C IS D CG G V G
Sbjct: 479 C----CVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQS 534
Query: 1094 -ECKCDEGYESGFMMMKNC-----MDIDECQRDPLLCRGGV-CHNTEGSYRCECPPGHQL 1146
E + GY +M+ C + + E +R P E + R G +
Sbjct: 535 CESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEA 594
Query: 1147 S-PNISACIDINECEL-SAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFC--------- 1195
PN D +EC L LC + C+N +G Y CAC PG+ D C
Sbjct: 595 ELPNSLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQP 653
Query: 1196 ------------------------VDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMP 1231
+ C NG C+ C+ GS CSC PG+A+M
Sbjct: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKD-NGPCKQVCSTVGGSAICSCFPGYAIMA 712
Query: 1232 DQRSCTDIDECEDNPNICDGGQ-CTNIPGEYRC----LCYDGFMASEDMKTCVDVNECDL 1286
D SC DI+EC + + C G+ C N G + C C G+ + C DV+EC +
Sbjct: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG--ECEDVDECAM 770
Query: 1287 NPNICLSG-TCENTKGSFIC----HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTN 1341
+ C G C+NTKGSF C C G+ + + C DINEC + C C N
Sbjct: 771 GTHTCQPGFLCQNTKGSFYCQARQRCMDGFL-QDPEGNCVDINECTSLSEPCRPGFSCIN 829
Query: 1342 TAGSFKCS-----CSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEG 1394
T GS+ C C+ G+ DG KC D++EC G H C + C N GSYRC CK G
Sbjct: 830 TVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAG 889
Query: 1395 YTGDGF--TCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL 1452
+ D F C D++EC + C N G YRC C GF+ +ADGK CED++EC
Sbjct: 890 FQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA 949
Query: 1453 PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCI-SGNCVNTPGSYIC 1511
C N+ G ++C C GY+L G CTD++EC + + C+N PGSY C
Sbjct: 950 QRCS--QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQC 1007
Query: 1512 DCP 1514
CP
Sbjct: 1008 ACP 1010
Score = 251 bits (642), Expect = 6e-66
Identities = 205/685 (29%), Positives = 284/685 (41%), Gaps = 132/685 (19%)
Query: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCD--DVNECETPGICGPGTC 1663
D DEC E+P + G N + Q C Y L E + + E ET G +C
Sbjct: 455 DNDECLEIP---ESGTEDNVCRTAQRHCCVSY-LQEKSCMAGVLGAKEGETCGAEDNDSC 510
Query: 1664 YNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSY 1723
++ C C ++V + +L Y + C+GE + +
Sbjct: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEV------ 564
Query: 1724 NIGRAWNKPCEQCPIPSTDEFATLCGSQRP--GFVIDIYTGLPVDI-DECREIPGVCENG 1780
+P E P A + G + G ++ LP D DEC +PG
Sbjct: 565 ------RRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH 618
Query: 1781 VCINMVGSFRCECPVGFFYNDKLLVCE--------------------------------- 1807
+CIN VGS+ C C GF D C
Sbjct: 619 LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLP 678
Query: 1808 DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQ-C 1865
+ C++ C++ C GS C C PGY + G C D NEC + CS G+ C
Sbjct: 679 QPNTCKDNGPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHC 736
Query: 1866 IDTVGSFYC----LCHTGFKTNDDQTMCLDINECE--RDACGNG-TCRNTIGSFNC---- 1914
++T+GSF+C C G+ D + C D++EC C G C+NT GSF C
Sbjct: 737 VNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 794
Query: 1915 RCNHGFILSHNNDCIDVDECASGNGNLCRNG-QCINTVGSFQCQ-----CNEGYEVAPDG 1968
RC GF+ +C+D++EC S CR G CINTVGS+ CQ C GY + DG
Sbjct: 795 RCMDGFLQDPEGNCVDINECTS-LSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 853
Query: 1969 RTCVDINECLLEPRKCAPG-TCQNLDGSYRCICPPGYSLQ--NEKCEDIDECVEEPEICA 2025
CVD+NEC +C G C NL GSYRC C G+ C D++EC P
Sbjct: 854 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 913
Query: 2026 LGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC 2085
TC NT GS++C C GF L++ G+RC+D+ + E +CS + + +C C
Sbjct: 914 QHTCENTLGSYRCSCASGFLLAADGKRCEDVN------ECEAQRCSQECANIYGSYQCYC 967
Query: 2086 ALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINT 2145
+G + C T+ DE C G+GI+ C +C+N
Sbjct: 968 R-QGYQLAEDGHTC-TDIDE-----CAQGAGIL------------------CTF-RCLNV 1001
Query: 2146 DGSYRCECP-FGYILA--GNECVDTDECSVG-NPCGNG-TCKNVIGGFECTCEEGFEPGP 2200
GSY+C CP GY + G C D DEC++G + C TC N+ G F C FE P
Sbjct: 1002 PGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL---RFECPP 1058
Query: 2201 -----------MMTCEDINECAQNP 2214
TC D EC +P
Sbjct: 1059 NYVQVSKTKCERTTCHDFLECQNSP 1083
Score = 246 bits (627), Expect = 3e-64
Identities = 174/576 (30%), Positives = 253/576 (43%), Gaps = 72/576 (12%)
Query: 2291 DENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYC----------- 2339
D++EC PG C+NT GSY C C GF+ + C EG+
Sbjct: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTC--RPEGHPPQPEAPQEPAL 661
Query: 2340 ---FTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGF 2396
F++V N + P+ + C D G P ++C G A P G
Sbjct: 662 KSEFSQVASNTIPL------PLPQPNTCKDNG----PCKQVCSTVGGSAICSCFP-GYAI 710
Query: 2397 MTNGA---DIDECKVIHDVCRNGE-CVNDRGSYHCI----CKTGYTPDITGTSCVDLNEC 2448
M +G DI+EC C GE CVN GS+HC C+ GY + C D++EC
Sbjct: 711 MADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA--LKDGECEDVDEC 768
Query: 2449 NQAPKPCN--FICKNTEGSYQCS----CPKGYILQEDGRSCKDLDECATKQHNCQ--FLC 2500
C F+C+NT+GS+ C C G++ +G +C D++EC + C+ F C
Sbjct: 769 AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSC 827
Query: 2501 VNTIGGFTCK-----CPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQ 2553
+NT+G +TC+ C G+ + T C+D NEC + ++ CG +C N PGS+ C+C+
Sbjct: 828 INTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCK 887
Query: 2554 RGFSLDQTGSSCEDVDEC--EGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENEC 2611
GF D G C DV+EC CQH C+N +G YRCSC G+L +C D NEC
Sbjct: 888 AGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC 947
Query: 2612 LSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECG-SAQAPCSYGCSNTEGGY 2670
A C C N GSY+C C G+Q + C DI+EC A C++ C N G Y
Sbjct: 948 -EAQRC-SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1005
Query: 2671 LCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKR 2730
C CP QG+ ++ G + + G N E C+ I G + R
Sbjct: 1006 QCACPE------QGYTMTANGRSCKDVDECALG--THNCSEAETCH--NIQGSFRCLRFE 1055
Query: 2731 RSTNETDASNIEDQSETEANVSLASWDVEKTAIFAFNI-SHVSNKVRILELLPALTTLTN 2789
N S + + T + + + N + + I + PA +
Sbjct: 1056 CPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGD 1115
Query: 2790 HNRYLIESGNEDGFF---KINQKEGISYLHFTKKKP 2822
I GNE+G+F ++N G+ YL +P
Sbjct: 1116 TIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEP 1151
Score = 241 bits (615), Expect = 8e-63
Identities = 178/558 (31%), Positives = 241/558 (43%), Gaps = 97/558 (17%)
Query: 2205 EDINECAQNP-LLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGK-------- 2255
+D +EC P LC C+NT GSY C C G+ L++D R C+ E + +
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
Query: 2256 ------------------HDCTEK---QMECKNLIGTYMCICGPGYQRRPDGEGCVDENE 2294
+ C + + C + G+ +C C PGY DG C D NE
Sbjct: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINE 722
Query: 2295 CQTKPGICENGR-CLNTRGSYTC----ECNDGFTASPNQDECLDNREGYCFTEVLQNMCQ 2349
C T C G C+NT GS+ C C G+ + E +D + + CQ
Sbjct: 723 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDE------CAMGTHTCQ 776
Query: 2350 IGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVI 2409
G +N TK C + C Q P G N DI+EC +
Sbjct: 777 PGFLCQN--TKGSFYCQARQ----RCMDGFLQD--------PEG-----NCVDINECTSL 817
Query: 2410 HDVCRNG-ECVNDRGSYHC-----ICKTGYTPDITGTSCVDLNECNQAPKPCNF--ICKN 2461
+ CR G C+N GSY C IC GY GT CVD+NEC C +C N
Sbjct: 818 SEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN 877
Query: 2462 TEGSYQCSCPKGYILQEDGRSCKDLDEC-ATKQHNCQFLCVNTIGGFTCKCPPGF--TQH 2518
GSY+C C G+ GR C D++EC A+ CQ C NT+G + C C GF
Sbjct: 878 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAAD 937
Query: 2519 HTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE--GNHR 2576
C D NEC + C + C N GS+ C C++G+ L + G +C D+DEC
Sbjct: 938 GKRCEDVNEC--EAQRCSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGIL 993
Query: 2577 CQHGCQNIIGGYRCSCP-QGYLQHYQWNQCVDENEC-LSAHICGGA-SCHNTLGSYKCM- 2632
C C N+ G Y+C+CP QGY C D +EC L H C A +CHN GS++C+
Sbjct: 994 CTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLR 1053
Query: 2633 --CPAGFQYEQFS------GGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQG 2684
CP Y Q S C D EC ++ A ++ N + G L P FRIG
Sbjct: 1054 FECPP--NYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLL--VPAHIFRIGPA 1109
Query: 2685 HCVSG----MGMGRGNPE 2698
+G + + +GN E
Sbjct: 1110 PAFTGDTIALNIIKGNEE 1127
Score = 230 bits (587), Expect = 1e-59
Identities = 183/571 (32%), Positives = 235/571 (41%), Gaps = 119/571 (20%)
Query: 2012 EDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCS 2071
+D DEC+ P C NT GS+ C C GFSL GR C+ G
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP-----------EGHPP 651
Query: 2072 SPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDEC 2131
P++ ALK E F Q+ S I P + C
Sbjct: 652 QPEAPQEP------ALKSE----------------FSQVA---SNTIPLP---LPQPNTC 683
Query: 2132 KEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVG-NPCGNGT-CKNVIGG 2187
K+ CK C GS C C GY + G C D +EC + C G C N +G
Sbjct: 684 KDNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGS 742
Query: 2188 FEC----TCEEGF--EPGPMMTCEDINECAQNPLLC--AFRCVNTYGSYEC----KCPVG 2235
F C TCE G+ + G CED++ECA C F C NT GS+ C +C G
Sbjct: 743 FHCYKALTCEPGYALKDGE---CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDG 799
Query: 2236 YVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMC-----ICGPGYQRRPDGEGCV 2290
+ L++ C D +EC C C N +G+Y C IC GY DG CV
Sbjct: 800 F-LQDPEGNCVDINECTSLSEPC-RPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCV 857
Query: 2291 DENECQTKPGICENGR-CLNTRGSYTCECNDGFTASPNQDECLDNREGYCFT-EVLQNMC 2348
D NEC+T C G+ C N GSY C+C GF C+D E + + Q+ C
Sbjct: 858 DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC 917
Query: 2349 QIGSSNRNPVTKSECCCDGG---RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDE 2405
+ N + C C G G CE D++E
Sbjct: 918 E------NTLGSYRCSCASGFLLAADGKRCE-------------------------DVNE 946
Query: 2406 CKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQ-APKPCNFICKNTEG 2464
C+ C EC N GSY C C+ GY G +C D++EC Q A C F C N G
Sbjct: 947 CEAQR--CSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPG 1003
Query: 2465 SYQCSCPK-GYILQEDGRSCKDLDECATKQHNCQ--FLCVNTIGGFTC---KCPPGFTQH 2518
SYQC+CP+ GY + +GRSCKD+DECA HNC C N G F C +CPP + Q
Sbjct: 1004 SYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQV 1063
Query: 2519 HTSCIDNNECTSDINLCGSKGICQNTPGSFT 2549
+ + C + CQN+P T
Sbjct: 1064 SKTKCERTTCHDFLE-------CQNSPARIT 1087
Score = 219 bits (558), Expect = 3e-56
Identities = 207/698 (29%), Positives = 281/698 (40%), Gaps = 136/698 (19%)
Query: 1965 APDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDE--CVE--E 2020
+P+G T I C CA G +D C+ P ++ C CV +
Sbjct: 433 SPEGSTKDLIETC------CAAGQQWAIDND-ECLEIPESGTEDNVCRTAQRHCCVSYLQ 485
Query: 2021 PEICALGTCSNTEGSFKCLCPEGFSLSSS-GRRCQDLRMSYCYAKFEGGKCSSPKSR--- 2076
+ C G EG C + S S ++C D + EG C S +
Sbjct: 486 EKSCMAGVLGAKEGE-TCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYP 544
Query: 2077 -NHSKQECCCALKGEGWGDPCELC----PTEP----------DEAFRQICPYGSGIIVGP 2121
NH CC +GE +P + P EP + A R+ G+ +
Sbjct: 545 CNHVMLSCC---EGE---EPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPN 598
Query: 2122 DDSAVDMDECK--EPDVCKHGQCINTDGSYRCECPFGYILA--GNEC------------- 2164
D DEC ++C+H CINT GSY C C G+ L G C
Sbjct: 599 SLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQ 657
Query: 2165 --------------------VDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPMMT 2203
+ C PC C V G C+C G+ ++
Sbjct: 658 EPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVS 716
Query: 2204 CEDINECAQNPLLCAF--RCVNTYGSYEC----KCPVGYVLREDRRMCKDEDECEEGKHD 2257
CEDINEC + C+ CVNT GS+ C C GY L++ C+D DEC G H
Sbjct: 717 CEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHT 774
Query: 2258 CTEKQMECKNLIGTYMCI----CGPGYQRRPDGEGCVDENECQTKPGICENG-RCLNTRG 2312
C + C+N G++ C C G+ + P+G CVD NEC + C G C+NT G
Sbjct: 775 C-QPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVG 832
Query: 2313 SYTCE-----CNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDG 2367
SYTC+ C G+ AS + +C+D E C T V + C G N C C
Sbjct: 833 SYTCQRNPLICARGYHASDDGTKCVDVNE--CETGV--HRCGEGQVCHNLPGSYRCDCKA 888
Query: 2368 GRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHC 2427
G FQ GRG + D++EC C N GSY C
Sbjct: 889 G-----------FQRDA-------FGRGCI----DVNECWASPGRLCQHTCENTLGSYRC 926
Query: 2428 ICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2487
C +G+ G C D+NEC + C+ C N GSYQC C +GY L EDG +C D+D
Sbjct: 927 SCASGFLLAADGKRCEDVNECEA--QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDID 984
Query: 2488 ECATKQHN-CQFLCVNTIGGFTCKCPP-GFTQ--HHTSCIDNNECTSDINLCGSKGICQN 2543
ECA C F C+N G + C CP G+T + SC D +EC + C C N
Sbjct: 985 ECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHN 1044
Query: 2544 TPGSFTC---ECQRGF-SLDQT---GSSCEDVDECEGN 2574
GSF C EC + + +T ++C D EC+ +
Sbjct: 1045 IQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNS 1082
Score = 216 bits (550), Expect = 3e-55
Identities = 188/665 (28%), Positives = 272/665 (40%), Gaps = 118/665 (17%)
Query: 1550 SNEIGVGVSKASC-CCSLG---KAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILE 1605
++ G+ + K C CC LG +A G CE P + ++ EG P +I+
Sbjct: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEP----LIVP 562
Query: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCY 1664
++ E + G T L ++ DD +EC PG C
Sbjct: 563 EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAEL-PNSLPGDDQDECLLLPGELCQHLCI 621
Query: 1665 NTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYN 1724
NTVG+Y C C P + + D +TC E
Sbjct: 622 NTVGSYHCACFPGF-------------------SLQDDGRTCRPE--------------- 647
Query: 1725 IGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCIN 1784
G Q P + EF+ + + P LP+ + G C+ VC
Sbjct: 648 -GHPPQPEAPQEPALKS-EFSQVASNTIP---------LPLPQPNTCKDNGPCKQ-VCST 695
Query: 1785 MVGSFRCECPVGFFYNDKLLVCEDIDECQNG-PVCQRNAECINTAGSYRC----DCKPGY 1839
+ GS C C G+ + CEDI+EC C R C+NT GS+ C C+PGY
Sbjct: 696 VGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 755
Query: 1840 RFTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYCL----CHTGFKTNDDQTMCLDINE 1894
G+C D +EC + C G C +T GSFYC C GF D + C+DINE
Sbjct: 756 ALKD-GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINE 813
Query: 1895 CER--DACGNG-TCRNTIGSFNCR-----CNHGFILSHNND-CIDVDECASGNGNLCRNG 1945
C + C G +C NT+GS+ C+ C G+ S + C+DV+EC +G + C G
Sbjct: 814 CTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV-HRCGEG 872
Query: 1946 Q-CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY 2004
Q C N GS++C C G++ GR C+D+NEC P + TC+N GSYRC C G+
Sbjct: 873 QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGF 932
Query: 2005 SL--QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCY 2062
L ++CED++EC E + C+ C+N GS++C C +G+ L+ G C D+
Sbjct: 933 LLAADGKRCEDVNEC--EAQRCS-QECANIYGSYQCYCRQGYQLAEDGHTCTDI------ 983
Query: 2063 AKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPD 2122
EC +G G C +++ CP +
Sbjct: 984 ------------------DEC-----AQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
Query: 2123 DSAVDMDECK-EPDVCKHGQ-CINTDGSYRC---ECPFGYILAGNECVDTDECSVGNPCG 2177
S D+DEC C + C N GS+RC ECP Y+ + C C
Sbjct: 1021 RSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1080
Query: 2178 NGTCK 2182
N +
Sbjct: 1081 NSPAR 1085
Score = 210 bits (534), Expect = 2e-53
Identities = 231/869 (26%), Positives = 328/869 (37%), Gaps = 216/869 (24%)
Query: 369 GVTVAPEMCPIRATEDFNKLCSVP-MVIPGRPEYP--PPPLGPIPPVLPVPPGFPPGPQI 425
GVT AP + K VP +PG P P P P + LP PP ++
Sbjct: 355 GVTHAPSL---------GKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREV 405
Query: 426 PVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCR------CECNKG 479
P P+VLP + + + R P GS + C +
Sbjct: 406 P-------------RKPQVLPHSHVEEDTDPNSVHSIPRSSPE-GSTKDLIETCCAAGQQ 451
Query: 480 FQLDLRGECIDVDEC--EKNPCAGGE---CINNQGSYTCQCRAGYQSTLTRTEC--RDID 532
+ +D EC+++ E E N C + C++ +C AG C D D
Sbjct: 452 WAID-NDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCM--AGVLGAKEGETCGAEDND 508
Query: 533 ECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR-NMCLNGMCINED 591
C I +C + C G V +G++CE N + C E+
Sbjct: 509 SC----GISLYKQCCDC-------CGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEE 557
Query: 592 GSFKC-ICKPGFQLASDGRYCK------------------------DINECET-PGICMN 625
+ +P A+ R + D +EC PG
Sbjct: 558 PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ 617
Query: 626 GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCC 685
C+NT GSY C CFPG ++ DGR C R + P A +
Sbjct: 618 HLCINTVGSYHCACFPGFSLQDDGRTC--------------RPEGHPPQPEAPQEPALKS 663
Query: 686 ASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGT 745
++ A P P N+ + C +C + G+
Sbjct: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQ------------------------VCSTVGGS 699
Query: 746 YKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ-CRNTPGSFVC----TCPKGFIYKP 800
C C GY + + G +C DINECV + C G+ C NT GSF C TC G+ K
Sbjct: 700 AICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD 759
Query: 801 DLKTCEDIDECE--SSPCING-VCKNSPGSFICE----CSSESTLDPTKTICIETIKGTC 853
CED+DEC + C G +C+N+ GSF C+ C DP
Sbjct: 760 G--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDP------------- 804
Query: 854 WQTVIDGRCEININGATLKSQCCSSLGAAWGSPCT------LCQVDP-ICGKGY-SRIKG 905
+G C ++IN T S+ C G C CQ +P IC +GY + G
Sbjct: 805 -----EGNC-VDINECTSLSEPCRP-----GFSCINTVGSYTCQRNPLICARGYHASDDG 853
Query: 906 TQCEDIDECEVFPGVCKNG-LCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYED 964
T+C D++ECE C G +C N GS++C C +G DA GR C+D+
Sbjct: 854 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV----------- 902
Query: 965 EECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKP 1024
+ C S G C+ Y C G A +GK
Sbjct: 903 -------------NECWASPGRL-----CQHTCENTLGSYRCSCASGFLLAA----DGKR 940
Query: 1025 FFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRG 1084
+D+NEC+ C+ +C N GS++C C G+ L + CTDIDEC +
Sbjct: 941 C-EDVNECEA--QRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTF 996
Query: 1085 QCVNTPGDFECKCDEGYESGFMMMKN---CMDIDECQRDPLLC-RGGVCHNTEGSYRC-- 1138
+C+N PG ++C C E G+ M N C D+DEC C CHN +GS+RC
Sbjct: 997 RCLNVPGSYQCACP---EQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLR 1053
Query: 1139 -ECPPGH-QLSP---NISACIDINECELS 1162
ECPP + Q+S + C D EC+ S
Sbjct: 1054 FECPPNYVQVSKTKCERTTCHDFLECQNS 1082
Score = 201 bits (511), Expect = 9e-51
Identities = 121/338 (35%), Positives = 151/338 (44%), Gaps = 54/338 (15%)
Query: 2400 GADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC-----VDLNECNQAPK- 2453
G D DEC ++ C+N GSYHC C G++ G +C E Q P
Sbjct: 602 GDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
Query: 2454 --------------------------PCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2487
PC +C GS CSC GY + DG SC+D++
Sbjct: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDIN 721
Query: 2488 ECATKQHNCQ--FLCVNTIGGFTC----KCPPGFTQHHTSCIDNNECTSDINLCGSKGIC 2541
EC T H C CVNT+G F C C PG+ C D +EC + C +C
Sbjct: 722 ECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLC 781
Query: 2542 QNTPGSFTCE----CQRGFSLDQTGSSCEDVDECEG-NHRCQHG--CQNIIGGYRCS--- 2591
QNT GSF C+ C GF D G +C D++EC + C+ G C N +G Y C
Sbjct: 782 QNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 840
Query: 2592 --CPQGYLQHYQWNQCVDENEC-LSAHICG-GASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2647
C +GY +CVD NEC H CG G CHN GSY+C C AGFQ + F GC
Sbjct: 841 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
Query: 2648 DINEC-GSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQG 2684
D+NEC S C + C NT G Y C C G+ G
Sbjct: 901 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADG 938
Score = 196 bits (498), Expect = 3e-49
Identities = 206/720 (28%), Positives = 283/720 (39%), Gaps = 132/720 (18%)
Query: 216 AWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPA 275
AW P P +P +P+ D + +IP G+ T E C A
Sbjct: 397 AWIPPTREVPRKPQ-----VLPHSHVEEDTDPNSVHSIPRSSPEGS---TKDLIETCCAA 448
Query: 276 GHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCK-CPPGFYTSPDGTRCIDVRPG 334
G + + +C +I E T +C + VS K C G + +G C
Sbjct: 449 GQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETC------ 502
Query: 335 YCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMV 394
A N C I+ + CCD C G+ V E + + C+ M+
Sbjct: 503 ---GAEDNDSCG------ISLYKQCCD---CCGLGLRVRAEGQSCESNPNLGYPCNHVML 550
Query: 395 IPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREP---------PRVL 445
E P L VP P PR E RE P L
Sbjct: 551 SCCEGEEP----------LIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
Query: 446 PVNVTDYCQLVR-YLCQNGRCIPTPGSCRCECNKGFQLD--------------------- 483
P + D C L+ LCQ+ CI T GS C C GF L
Sbjct: 601 PGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP 659
Query: 484 -LRGECIDV------------DECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRD 530
L+ E V + C+ N C GS C C GY C D
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCED 719
Query: 531 IDECLQNGRICNNG-RCINTDGSFHC----VCNAGFHVTRDGKNCEDMDECSI-RNMCLN 584
I+EC+ + C+ G C+NT GSFHC C G+ +DG+ CED+DEC++ + C
Sbjct: 720 INECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDGE-CEDVDECAMGTHTCQP 777
Query: 585 G-MCINEDGSFKC----ICKPGFQLASDGRYCKDINECET-PGICMNG-RCVNTDGSYRC 637
G +C N GSF C C GF +G C DINEC + C G C+NT GSY C
Sbjct: 778 GFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYTC 836
Query: 638 E-----CFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAF 692
+ C G DG CVD + T GQ L G+ + +C AF
Sbjct: 837 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSY-RCDCKAGFQRDAF 895
Query: 693 GEPC---QPCPA------QNSAE-----YQALCSSGPGMTSAG---SDINECALDPDICP 735
G C C A Q++ E Y+ C+SG + + G D+NEC + C
Sbjct: 896 GRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCS 953
Query: 736 NGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCP-K 794
C N+ G+Y+C C GY++ G C DI+EC + + +C N PGS+ C CP +
Sbjct: 954 QE-CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQ 1012
Query: 795 GFIYKPDLKTCEDIDECE--SSPCING-VCKNSPGSFIC---ECSSESTLDPTKTICIET 848
G+ + ++C+D+DEC + C C N GSF C EC + + +KT C T
Sbjct: 1013 GYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFEC-PPNYVQVSKTKCERT 1071
Score = 188 bits (477), Expect = 8e-47
Identities = 178/629 (28%), Positives = 241/629 (38%), Gaps = 120/629 (19%)
Query: 201 GIVCTKTLC-CATVG---RAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGL 256
GI K C C +G RA G CE P +PC + +C + +E +P +
Sbjct: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVML------SCCEGEEPLIVPEV 564
Query: 257 CQGGNCINTVGSFECKCPAGHKLNEVSQKCE--------DIDECSTIPGICEGGECTNTV 308
+ AG + + + E D DEC +PG C NTV
Sbjct: 565 RRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTV 624
Query: 309 SSYFCKCPPGFYTSPDGTRCIDVRP-GY----------CYTALTNGRCSNQLPQSITKMQ 357
SY C C PGF DG C RP G+ + + SN +P + +
Sbjct: 625 GSYHCACFPGFSLQDDGRTC---RPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPN 681
Query: 358 CCCDAGRCWSPGVTVAPE-----------MCPIRATEDFNKLCSVPMVIPGRPEYPPPPL 406
C D G C TV M + ED N+ C + R E+ L
Sbjct: 682 TCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINE-CVTDLHTCSRGEHCVNTL 740
Query: 407 GPIP--PVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNG- 463
G L PG Y E V D C + + CQ G
Sbjct: 741 GSFHCYKALTCEPG---------------YALKDGECEDV------DECAMGTHTCQPGF 779
Query: 464 RCIPTPGSCRCE----CNKGFQLDLRGECIDVDECE--KNPCAGG-ECINNQGSYTCQ-- 514
C T GS C+ C GF D G C+D++EC PC G CIN GSYTCQ
Sbjct: 780 LCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRN 839
Query: 515 ---CRAGYQSTLTRTECRDIDECLQNGRICNNGR-CINTDGSFHCVCNAGFHVTRDGKNC 570
C GY ++ T+C D++EC C G+ C N GS+ C C AGF G+ C
Sbjct: 840 PLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC 899
Query: 571 EDMDEC--SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRC 628
D++EC S +C + C N GS++C C GF LA+DG+ C+D+NECE + C
Sbjct: 900 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQEC 956
Query: 629 VNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCAST 688
N GSY+C C G + DG C D + G +C+ +C C
Sbjct: 957 ANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCL----NVPGSYQCACPEQ 1012
Query: 689 EYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNG-ICENLRGTYK 747
Y + C D++ECAL C C N++G+++
Sbjct: 1013 GYTMTANGRSC----------------------KDVDECALGTHNCSEAETCHNIQGSFR 1050
Query: 748 CI---CNSGYEVDSTGK----NCVDINEC 769
C+ C Y S K C D EC
Sbjct: 1051 CLRFECPPNYVQVSKTKCERTTCHDFLEC 1079
Score = 171 bits (433), Expect = 1e-41
Identities = 193/745 (25%), Positives = 273/745 (36%), Gaps = 175/745 (23%)
Query: 1140 CPPGHQLSPNISACIDINECELSAHLCPNGR---CVNLIGKYQCACNPGYHSTPDRLFCV 1196
C G Q + + C++I E ++C + CV+ + + C +
Sbjct: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAE 505
Query: 1197 DIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNI---CDGGQ 1253
D D C I S C C G L R + CE NPN+ C+
Sbjct: 506 DNDSCGI-----------SLYKQCCDCC-GLGL----RVRAEGQSCESNPNLGYPCNHVM 549
Query: 1254 CTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLS-GTCENTKGSFICHCDMGYS 1312
+ GE + + E V+E ++ LS GT S
Sbjct: 550 LSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL--------- 600
Query: 1313 GKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKC--------- 1361
D +EC + +H +C NT GS+ C+C PG+ DG C
Sbjct: 601 ------PGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQP 653
Query: 1362 ---------TDLDECSNGT--------HMCSQHADCKNTM----GSYRCLCKEGYT--GD 1398
++ + ++ T + C + CK GS C C GY D
Sbjct: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713
Query: 1399 GFTCTDLDECSENLNLCGNGQ-CLNAPGGYRC----ECDMGFVPSADGKACEDIDECSL- 1452
G +C D++EC +L+ C G+ C+N G + C C+ G+ DG+ CED+DEC++
Sbjct: 714 GVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMG 771
Query: 1453 PNICVFG-TCHNLPGLFRCE----CEIGYELDRSGGNCTDVNECLDPTT-CISG-NCVNT 1505
+ C G C N G F C+ C G+ D G NC D+NEC + C G +C+NT
Sbjct: 772 THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINT 830
Query: 1506 PGSYICD-----CPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA 1560
GSY C C + + CVD NE GV +
Sbjct: 831 VGSYTCQRNPLICARGYHASDDGTKCVDV---------------------NECETGVHR- 868
Query: 1561 SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPG-LCQG 1619
C G+ C P Y+ C G F+ + D++EC PG LCQ
Sbjct: 869 ---CGEGQV----CHNLPG----SYRCDCKAG--FQRDAFGRGCIDVNECWASPGRLCQH 915
Query: 1620 GKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYM 1679
C NT GS++C C +G+ L D + C+DVNECE C C N G+Y C C Y
Sbjct: 916 -TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR-CSQ-ECANIYGSYQCYCRQGYQ 972
Query: 1680 QVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIP 1739
G+ C D+ C+ G C P
Sbjct: 973 LAEDGHTCTDIDE----------------------------CAQGAGILCTFRCLNVP-- 1002
Query: 1740 STDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVC-ENGVCINMVGSFRC---ECPV 1795
+ C G+ + D+DEC C E C N+ GSFRC ECP
Sbjct: 1003 ----GSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPP 1058
Query: 1796 GFFYNDKL----LVCEDIDECQNGP 1816
+ K C D ECQN P
Sbjct: 1059 NYVQVSKTKCERTTCHDFLECQNSP 1083
Score = 94.0 bits (232), Expect = 2e-18
Identities = 85/307 (27%), Positives = 117/307 (38%), Gaps = 54/307 (17%)
Query: 96 RPNMC--TCPSGQIAPSCGSRSIQHC---------NIRCMNGGSCSDDHCLCQKGY---- 140
+PN C P Q+ + G +I C + C + C D C +G
Sbjct: 679 QPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVN 738
Query: 141 -IGT-HCGQPV-CESG-CLNGGRCVAPNRCA-----CTYGFTGPQCERDYRTGPCFTVIS 191
+G+ HC + + CE G L G C + CA C GF C+ T F +
Sbjct: 739 TLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFL---CQN---TKGSFYCQA 792
Query: 192 NQMCQGQLSGIVCTKTLCCATVGR--AWGHPCE------------MCPAQPHPCRRGFIP 237
Q C + G + C + + PC C P C RG+
Sbjct: 793 RQRC---MDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHA 849
Query: 238 NIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIP 296
+ C DV+EC+ C +G C N GS+ C C AG + + + C D++EC P
Sbjct: 850 SDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASP 909
Query: 297 GICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKM 356
G C NT+ SY C C GF + DG RC DV C RCS +
Sbjct: 910 GRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE--CEAQ----RCSQECANIYGSY 963
Query: 357 QCCCDAG 363
QC C G
Sbjct: 964 QCYCRQG 970
Score = 89.0 bits (219), Expect = 6e-17
Identities = 86/268 (32%), Positives = 102/268 (38%), Gaps = 56/268 (20%)
Query: 86 RHSCGDGFCSRP-------NMCTCPSGQIAP--SC----GSRSIQHCNIRCMNGGSCSDD 132
R C DGF P N CT S P SC GS + Q + C G SDD
Sbjct: 793 RQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 852
Query: 133 HCLCQKGYIGTHCGQP-VCESG---CLNGGRC---VAPNRCACTYGFTGPQCERDYRTGP 185
GT C CE+G C G C RC C GF +RD
Sbjct: 853 ---------GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF-----QRDAFGRG 898
Query: 186 CFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH-PCRRGFIPNIRTGAC 244
C V C A+ GR H CE C GF+ C
Sbjct: 899 CIDVNE-----------------CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRC 941
Query: 245 QDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC 304
+DV+EC+A C C N GS++C C G++L E C DIDEC+ GI C
Sbjct: 942 EDVNECEA--QRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC 998
Query: 305 TNTVSSYFCKCPPGFYT-SPDGTRCIDV 331
N SY C CP YT + +G C DV
Sbjct: 999 LNVPGSYQCACPEQGYTMTANGRSCKDV 1026
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 276 bits (706), Expect = 2e-73
Identities = 197/583 (33%), Positives = 257/583 (44%), Gaps = 100/583 (17%)
Query: 909 EDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECT 968
+D DEC + PG LC+NT GS+ C C G +L GR TC R E
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGR--------TC--RPEGHP-- 650
Query: 969 LPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKP---F 1025
P P+ L A+ I P
Sbjct: 651 ----------------------------PQPEAPQEPALKSEFSQVASNTIPLPLPQPNT 682
Query: 1026 FKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ 1085
KD CK + C GS C C G+A+ ++ +C D DEC + C R Q
Sbjct: 683 CKDNGPCKQV--------CSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQ 734
Query: 1086 -CVNTPGDFECK-----CDEGYESGFMMMKNCMDIDECQRDPLLC-RGGVCHNTEGSYRC 1138
CVNT G F C C +GY + C+DI+EC D C RG C NT GS+ C
Sbjct: 735 FCVNTLGSFYCVNHTVLCADGYILN--AHRKCVDINECVTDLHTCSRGEHCVNTLGSFHC 792
Query: 1139 ----ECPPGHQLSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCA----CNPGYHST 1189
C PG+ L C D++EC + H C P C N G + C C G+
Sbjct: 793 YKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQD 850
Query: 1190 PDRLFCVDIDECSIMNGGCET--FCTNSEGSYECS-----CQPGFALMPDQRSCTDIDEC 1242
P+ CVDI+EC+ ++ C C N+ GSY C C G+ D C D++EC
Sbjct: 851 PEGN-CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC 909
Query: 1243 EDNPNICDGGQ-CTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKG 1301
E + C GQ C N+PG YRC C GF + C+DVNEC +P TCENT G
Sbjct: 910 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG 969
Query: 1302 SFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGI 1359
S+ C C G+ C D+NECE A C + C N GS++C C G+ DG
Sbjct: 970 SYRCSCASGFLLAADGKRCEDVNECE--AQRCSQE--CANIYGSYQCYCRQGYQLAEDGH 1025
Query: 1360 KCTDLDECSNGTH-MCSQHADCKNTMGSYRCLCKE-GY--TGDGFTCTDLDECSENLNLC 1415
CTD+DEC+ G +C+ C N GSY+C C E GY T +G +C D+DEC+ + C
Sbjct: 1026 TCTDIDECAQGAGILCTFR--CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNC 1083
Query: 1416 GNGQ-CLNAPGGYRC---ECDMGFVPSADGK----ACEDIDEC 1450
+ C N G +RC EC +V + K C D EC
Sbjct: 1084 SEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1126
Score = 270 bits (689), Expect = 2e-71
Identities = 214/747 (28%), Positives = 297/747 (39%), Gaps = 149/747 (19%)
Query: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ-- 1085
D N IP G ++ I + C +A+D++E C +I E ++C Q
Sbjct: 422 DPNSVHSIPRSSPEGSTKDLIETC-CAAGQQWAIDNDE--CLEIPESGTEDNVCRTAQRH 478
Query: 1086 -CVNTPGDFECKC-------------DEGYESGFMMMKNCMDI-----------DECQRD 1120
CV+ + C ++ G + K C D C+ +
Sbjct: 479 CCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESN 538
Query: 1121 PLL---CRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGK 1177
P L C + EG P + +A ++E E++ GR +G
Sbjct: 539 PNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMA------GREALSLGT 592
Query: 1178 YQCACNPGYHSTPDRLFCVDIDECSIMNGG-CETFCTNSEGSYECSCQPGFALMPDQRSC 1236
P+ L D DEC ++ G C+ C N+ GSY C+C PGF+L D R+C
Sbjct: 593 EA--------ELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTC 644
Query: 1237 ------------------TDIDECEDN--------PNIC-DGGQ----CTNIPGEYRCLC 1265
++ + N PN C D G C+ + G C C
Sbjct: 645 RPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSC 704
Query: 1266 YDGFMASEDMKTCVDVNECDLNPNICLSGT-CENTKGSFIC-----HCDMGYSGKKGKTG 1319
+ G+ D +C D +EC + + C C NT GSF C C GY
Sbjct: 705 FPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYI-LNAHRK 763
Query: 1320 CTDINECEIGAHNCGKHAVCTNTAGSFKC----SCSPGWIGDGIKCTDLDECSNGTHMCS 1375
C DINEC H C + C NT GSF C +C PG+ +C D+DEC+ GTH C
Sbjct: 764 CVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQ 823
Query: 1376 QHADCKNTMGSYRC----LCKEGYTGD-GFTCTDLDECSENLNLCGNG-QCLNAPGGYRC 1429
C+NT GS+ C C +G+ D C D++EC+ C G C+N G Y C
Sbjct: 824 PGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTC 883
Query: 1430 E-----CDMGFVPSADGKACEDIDECSL-PNICVFG-TCHNLPGLFRCECEIGYELDRSG 1482
+ C G+ S DG C D++EC + C G CHNLPG +RC+C+ G++ D G
Sbjct: 884 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFG 943
Query: 1483 GNCTDVNEC-LDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPR 1541
C DVNEC P C NT GSY C C F L C D
Sbjct: 944 RGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA------- 996
Query: 1542 GDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPIT 1601
CS E C C G C
Sbjct: 997 -----QRCSQECANIYGSYQCYCRQGYQLAEDGHTC------------------------ 1027
Query: 1602 VILEDIDECQELPGLCQGGKCINTFGSFQCRCP-TGYYLNEDTRVCDDVNECE--TPGIC 1658
DIDEC + G+ +C+N GS+QC CP GY + + R C DV+EC T
Sbjct: 1028 ---TDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCS 1084
Query: 1659 GPGTCYNTVGNYTCI---CPPDYMQVN 1682
TC+N G++ C+ CPP+Y+QV+
Sbjct: 1085 EAETCHNIQGSFRCLRFECPPNYVQVS 1111
Score = 263 bits (672), Expect = 2e-69
Identities = 241/800 (30%), Positives = 325/800 (40%), Gaps = 124/800 (15%)
Query: 1965 APDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDE--CVE--E 2020
+P+G T I C CA G +D C+ P ++ C CV +
Sbjct: 433 SPEGSTKDLIETC------CAAGQQWAIDND-ECLEIPESGTEDNVCRTAQRHCCVSYLQ 485
Query: 2021 PEICALGTCSNTEGSFKCLCPEGFSLSSS-GRRCQDLRMSYCYAKFEGGKCSSPKSR--- 2076
+ C G EG C + S S ++C D + EG C S +
Sbjct: 486 EKSCMAGVLGAKEGE-TCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYP 544
Query: 2077 -NHSKQECCCALKGEGWGDPCELC----PTEP----------DEAFRQICPYGSGIIVGP 2121
NH CC +GE +P + P EP + A R+ G+ +
Sbjct: 545 CNHVMLSCC---EGE---EPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPN 598
Query: 2122 DDSAVDMDECK--EPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCG 2177
D DEC ++C+H CINT GSY C C G+ L G C
Sbjct: 599 SLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQ 657
Query: 2178 NGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYV 2237
K+ P P TC+D C Q C GS C C GY
Sbjct: 658 EPALKSEFSQVASNTIPLPLPQPN-TCKDNGPCKQV-------CSTVGGSAICSCFPGYA 709
Query: 2238 LREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI-----CGPGYQRRPDGEGCVDE 2292
+ D C+D+DEC G HDC+ +Q C N +G++ C+ C GY + CVD
Sbjct: 710 IMADGVSCEDQDECLMGAHDCSRRQF-CVNTLGSFYCVNHTVLCADGYILNAHRK-CVDI 767
Query: 2293 NECQTKPGICENG-RCLNTRGSYTC----ECNDGFTASPNQDECLDNREGYCFTEVLQNM 2347
NEC T C G C+NT GS+ C C G+ + E +D + +
Sbjct: 768 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDE------CAMGTHT 821
Query: 2348 CQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECK 2407
CQ G +N TK C + C Q P G N DI+EC
Sbjct: 822 CQPGFLCQN--TKGSFYCQARQ----RCMDGFLQD--------PEG-----NCVDINECT 862
Query: 2408 VIHDVCRNG-ECVNDRGSYHC-----ICKTGYTPDITGTSCVDLNECNQAPKPC--NFIC 2459
+ + CR G C+N GSY C IC GY GT CVD+NEC C +C
Sbjct: 863 SLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVC 922
Query: 2460 KNTEGSYQCSCPKGYILQEDGRSCKDLDEC-ATKQHNCQFLCVNTIGGFTCKCPPGF--T 2516
N GSY+C C G+ GR C D++EC A+ CQ C NT+G + C C GF
Sbjct: 923 HNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLA 982
Query: 2517 QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE--GN 2574
C D NEC + C + C N GS+ C C++G+ L + G +C D+DEC
Sbjct: 983 ADGKRCEDVNEC--EAQRCSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAG 1038
Query: 2575 HRCQHGCQNIIGGYRCSCP-QGYLQHYQWNQCVDENEC-LSAHICGGA-SCHNTLGSYKC 2631
C C N+ G Y+C+CP QGY C D +EC L H C A +CHN GS++C
Sbjct: 1039 ILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
Query: 2632 M---CPAGFQYEQFS------GGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIG 2682
+ CP Y Q S C D EC ++ A ++ N + G L P FRIG
Sbjct: 1099 LRFECPP--NYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLL--VPAHIFRIG 1154
Query: 2683 QGHCVSG----MGMGRGNPE 2698
+G + + +GN E
Sbjct: 1155 PAPAFTGDTIALNIIKGNEE 1174
Score = 243 bits (619), Expect = 3e-63
Identities = 212/731 (29%), Positives = 292/731 (39%), Gaps = 177/731 (24%)
Query: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCD--DVNECETPGICGPGTC 1663
D DEC E+P + G N + Q C Y L E + + E ET G +C
Sbjct: 455 DNDECLEIP---ESGTEDNVCRTAQRHCCVSY-LQEKSCMAGVLGAKEGETCGAEDNDSC 510
Query: 1664 YNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSY 1723
++ C C ++V + +L Y + C+GE + +
Sbjct: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEV------ 564
Query: 1724 NIGRAWNKPCEQCPIPSTDEFATLCGSQRP--GFVIDIYTGLPVDI-DECREIPGVCENG 1780
+P E P A + G + G ++ LP D DEC +PG
Sbjct: 565 ------RRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH 618
Query: 1781 VCINMVGSFRCECPVGFFYNDKLLVCE--------------------------------- 1807
+CIN VGS+ C C GF D C
Sbjct: 619 LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLP 678
Query: 1808 DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQ-C 1865
+ C++ C++ C GS C C PGY + G C D++EC + CS Q C
Sbjct: 679 QPNTCKDNGPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFC 736
Query: 1866 IDTVGSFYCLCHT-----GFKTNDDQTMCLDINECERD--ACGNGT-CRNTIGSFNC--- 1914
++T+GSFYC+ HT G+ N + C+DINEC D C G C NT+GSF+C
Sbjct: 737 VNTLGSFYCVNHTVLCADGYILNAHR-KCVDINECVTDLHTCSRGEHCVNTLGSFHCYKA 795
Query: 1915 -RCNHGFILSHNNDCIDVDECASGN-----GNLCRNGQ---------------------- 1946
C G+ L + +C DVDECA G G LC+N +
Sbjct: 796 LTCEPGYALK-DGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN 854
Query: 1947 -------------------CINTVGSFQCQ-----CNEGYEVAPDGRTCVDINECLLEPR 1982
CINTVGS+ CQ C GY + DG CVD+NEC
Sbjct: 855 CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVH 914
Query: 1983 KCAPG-TCQNLDGSYRCICPPGYSLQ--NEKCEDIDECVEEPEICALGTCSNTEGSFKCL 2039
+C G C NL GSYRC C G+ C D++EC P TC NT GS++C
Sbjct: 915 RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCS 974
Query: 2040 CPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELC 2099
C GF L++ G+RC+D+ + E +CS + + +C C +G + C
Sbjct: 975 CASGFLLAADGKRCEDVN------ECEAQRCSQECANIYGSYQCYCR-QGYQLAEDGHTC 1027
Query: 2100 PTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECP-FGYI 2158
T+ DE C G+GI+ C +C+N GSY+C CP GY
Sbjct: 1028 -TDIDE-----CAQGAGIL------------------CTF-RCLNVPGSYQCACPEQGYT 1062
Query: 2159 LA--GNECVDTDECSVG-NPCGNG-TCKNVIGGFECTCEEGFEPGP-----------MMT 2203
+ G C D DEC++G + C TC N+ G F C FE P T
Sbjct: 1063 MTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL---RFECPPNYVQVSKTKCERTT 1119
Query: 2204 CEDINECAQNP 2214
C D EC +P
Sbjct: 1120 CHDFLECQNSP 1130
Score = 243 bits (619), Expect = 3e-63
Identities = 177/542 (32%), Positives = 243/542 (44%), Gaps = 104/542 (19%)
Query: 1848 NDRNECQEIPN-ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCL---------------- 1890
+D++EC +P +C H CI+TVGS++C C GF DD C
Sbjct: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
Query: 1891 -----------------DINECERDACGNGTCRNTIGSFNCRCNHGF-ILSHNNDCIDVD 1932
N C+ + C GS C C G+ I++ C D D
Sbjct: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQD 721
Query: 1933 ECASGNGNLCRNGQCINTVGSFQC-----QCNEGYEVAPDGRTCVDINECLLEPRKCAPG 1987
EC G + R C+NT+GSF C C +GY + R CVDINEC+ + C+ G
Sbjct: 722 ECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGY-ILNAHRKCVDINECVTDLHTCSRG 780
Query: 1988 T-CQNLDGSYRC----ICPPGYSLQNEKCEDIDECVEEPEICALG-TCSNTEGSFKC--- 2038
C N GS+ C C PGY+L++ +CED+DEC C G C NT+GSF C
Sbjct: 781 EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR 840
Query: 2039 -LCPEGF---------------SLSS---SGRRCQDLRMSYCYAK-----FEGGKCSSPK 2074
C +GF SLS G C + SY + G S
Sbjct: 841 QRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
Query: 2075 SRNHSKQECCCALKGEGWGDPCELCPTE---PDEAFRQICPYGSGIIVGPDDSAVDMDEC 2131
++ EC + G G C P +A Q +G G +D++EC
Sbjct: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRG--------CIDVNEC 952
Query: 2132 --KEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVIGG 2187
+C+H C NT GSYRC C G++LA G C D +EC C C N+ G
Sbjct: 953 WASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECE-AQRCSQ-ECANIYGS 1009
Query: 2188 FECTCEEGFE-PGPMMTCEDINECAQNP-LLCAFRCVNTYGSYECKCP-VGYVLREDRRM 2244
++C C +G++ TC DI+ECAQ +LC FRC+N GSY+C CP GY + + R
Sbjct: 1010 YQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRS 1069
Query: 2245 CKDEDECEEGKHDCTEKQMECKNLIGTYMCI---CGPGY----QRRPDGEGCVDENECQT 2297
CKD DEC G H+C+E + C N+ G++ C+ C P Y + + + C D ECQ
Sbjct: 1070 CKDVDECALGTHNCSEAE-TCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQN 1128
Query: 2298 KP 2299
P
Sbjct: 1129 SP 1130
Score = 228 bits (580), Expect = 9e-59
Identities = 165/536 (30%), Positives = 218/536 (40%), Gaps = 97/536 (18%)
Query: 1228 ALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTC--------- 1278
A +P+ D DEC P C N G Y C C+ GF +D +TC
Sbjct: 594 AELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQP 653
Query: 1279 --------------VDVNECDL---NPNICLSG-----TCENTKGSFICHCDMGYSGKKG 1316
V N L PN C C GS IC C GY+
Sbjct: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMAD 713
Query: 1317 KTGCTDINECEIGAHNCGKHAVCTNTAGSFKCS-----CSPGWIGDGI-KCTDLDECSNG 1370
C D +EC +GAH+C + C NT GSF C C+ G+I + KC D++EC
Sbjct: 714 GVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTD 773
Query: 1371 THMCSQHADCKNTMGSYRCL----CKEGYTGDGFTCTDLDECSENLNLCGNG-QCLNAPG 1425
H CS+ C NT+GS+ C C+ GY C D+DEC+ + C G C N G
Sbjct: 774 LHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKG 833
Query: 1426 GYRCE----CDMGFVPSADGKACEDIDEC-SLPNICVFG-TCHNLPGLFRCE-----CEI 1474
+ C+ C GF+ +G C DI+EC SL C G +C N G + C+ C
Sbjct: 834 SFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICAR 892
Query: 1475 GYELDRSGGNCTDVNECLDPT-TCISGN-CVNTPGSYICDCPPDFELNPTRVGCVDTRSG 1532
GY G C DVNEC C G C N PGSY CDC F+ + GC+D
Sbjct: 893 GYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE- 951
Query: 1533 NCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGG 1592
C+ G C N +G C C+ G + C
Sbjct: 952 -CWAS---PGRLCQHTCENTLG----SYRCSCASGFLLAADGKRC--------------- 988
Query: 1593 EGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC 1652
ED++EC+ C +C N +GS+QC C GY L ED C D++EC
Sbjct: 989 ------------EDVNECEAQR--CSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC 1033
Query: 1653 -ETPGICGPGTCYNTVGNYTCICPPD-YMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
+ GI C N G+Y C CP Y G +C D+ + ++ +TC
Sbjct: 1034 AQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETC 1089
Score = 226 bits (575), Expect = 3e-58
Identities = 195/679 (28%), Positives = 285/679 (41%), Gaps = 99/679 (14%)
Query: 1550 SNEIGVGVSKASC-CCSLG---KAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILE 1605
++ G+ + K C CC LG +A G CE P + ++ EG P +I+
Sbjct: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEP----LIVP 562
Query: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCY 1664
++ E + G T L ++ DD +EC PG C
Sbjct: 563 EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAEL-PNSLPGDDQDECLLLPGELCQHLCI 621
Query: 1665 NTVGNYTCICPPDYMQVNGGNNCM--------DMRRSLCYRNYYADNQTCDGELLFNMTK 1716
NTVG+Y C C P + + G C + + ++ ++ Q + + +
Sbjct: 622 NTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFS--QVASNTIPLPLPQ 679
Query: 1717 KMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGV 1776
C N PC+Q + ST + +C S PG+ I D DEC
Sbjct: 680 PNTCKD-------NGPCKQ--VCSTVGGSAIC-SCFPGYAIMADGVSCEDQDECLMGAHD 729
Query: 1777 CENG-VCINMVGSFRCE-----CPVGFFYNDKLLVCEDIDECQNG-PVCQRNAECINTAG 1829
C C+N +GSF C C G+ N C DI+EC C R C+NT G
Sbjct: 730 CSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTDLHTCSRGEHCVNTLG 788
Query: 1830 SYRC----DCKPGYRFTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYCL----CHTGF 1880
S+ C C+PGY G+C D +EC + C G C +T GSFYC C GF
Sbjct: 789 SFHCYKALTCEPGYALKD-GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 847
Query: 1881 KTNDDQTMCLDINECER--DACGNG-TCRNTIGSFNCR-----CNHGFILSHNND-CIDV 1931
D + C+DINEC + C G +C NT+GS+ C+ C G+ S + C+DV
Sbjct: 848 -LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDV 906
Query: 1932 DECASGNGNLCRNGQ-CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQ 1990
+EC +G + C GQ C N GS++C C G++ GR C+D+NEC P + TC+
Sbjct: 907 NECETGV-HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCE 965
Query: 1991 NLDGSYRCICPPGYSL--QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSS 2048
N GSYRC C G+ L ++CED++EC E + C+ C+N GS++C C +G+ L+
Sbjct: 966 NTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCS-QECANIYGSYQCYCRQGYQLAE 1022
Query: 2049 SGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFR 2108
G C D+ EC +G G C +++
Sbjct: 1023 DGHTCTDI------------------------DEC-----AQGAGILCTFRCLNVPGSYQ 1053
Query: 2109 QICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQ-CINTDGSYRC---ECPFGYILAGNE 2163
CP + S D+DEC C + C N GS+RC ECP Y+
Sbjct: 1054 CACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKT 1113
Query: 2164 CVDTDECSVGNPCGNGTCK 2182
+ C C N +
Sbjct: 1114 KCERTTCHDFLECQNSPAR 1132
Score = 224 bits (570), Expect = 1e-57
Identities = 168/580 (28%), Positives = 252/580 (43%), Gaps = 105/580 (18%)
Query: 721 GSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC----------------- 763
G D +EC L P +C N G+Y C C G+ + G+ C
Sbjct: 602 GDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
Query: 764 -VDINECVLNSL--------LC-DNGQCR----NTPGSFVCTCPKGFIYKPDLKTCEDID 809
+ ++ N++ C DNG C+ GS +C+C G+ D +CED D
Sbjct: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQD 721
Query: 810 EC--ESSPCI-NGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVID-GRCEIN 865
EC + C C N+ GSF C + +C + + +D C +
Sbjct: 722 ECLMGAHDCSRRQFCVNTLGSFYCVNHT--------VLCADGYILNAHRKCVDINECVTD 773
Query: 866 INGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNG- 924
++ + C ++LG+ C C GY+ +K +CED+DEC + C+ G
Sbjct: 774 LHTCSRGEHCVNTLGSFH------CYKALTCEPGYA-LKDGECEDVDECAMGTHTCQPGF 826
Query: 925 LCVNTRGSFKCQ----CPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDAC 980
LC NT+GSF CQ C G D G C+DI ECT +C
Sbjct: 827 LCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDI-----------NECTSLSEPCRPGFSC 874
Query: 981 CCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCT 1040
+V G+ C+ P+ +C RG ++ D+NEC+ C
Sbjct: 875 INTV----GSYTCQRNPL--------ICARG-----YHASDDGTKCVDVNECETGVHRCG 917
Query: 1041 HGK-CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDE 1099
G+ C N GS++C C +GF D+ R C D++EC SP + C NT G + C C
Sbjct: 918 EGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSC-- 975
Query: 1100 GYESGFMMM---KNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDI 1156
SGF++ K C D++EC+ C N GSY+C C G+QL+ + C DI
Sbjct: 976 --ASGFLLAADGKRCEDVNECEAQRC---SQECANIYGSYQCYCRQGYQLAEDGHTCTDI 1030
Query: 1157 NECELSAHLCPNGRCVNLIGKYQCAC-NPGYHSTPDRLFCVDIDECSIMNGGCE--TFCT 1213
+EC A + RC+N+ G YQCAC GY T + C D+DEC++ C C
Sbjct: 1031 DECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCH 1090
Query: 1214 NSEGSYEC---SCQPGFALMP----DQRSCTDIDECEDNP 1246
N +GS+ C C P + + ++ +C D EC+++P
Sbjct: 1091 NIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1130
Score = 206 bits (524), Expect = 3e-52
Identities = 221/800 (27%), Positives = 310/800 (38%), Gaps = 169/800 (21%)
Query: 216 AWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPA 275
AW P P +P +P+ D + +IP G+ T E C A
Sbjct: 397 AWIPPTREVPRKPQ-----VLPHSHVEEDTDPNSVHSIPRSSPEGS---TKDLIETCCAA 448
Query: 276 GHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCK-CPPGFYTSPDGTRCIDVRPG 334
G + + +C +I E T +C + VS K C G + +G C
Sbjct: 449 GQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETC------ 502
Query: 335 YCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMV 394
A N C I+ + CCD C G+ V E + + C+ M+
Sbjct: 503 ---GAEDNDSCG------ISLYKQCCD---CCGLGLRVRAEGQSCESNPNLGYPCNHVML 550
Query: 395 IPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREP---------PRVL 445
E P L VP P PR E RE P L
Sbjct: 551 SCCEGEEP----------LIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
Query: 446 PVNVTDYCQLVR-YLCQNGRCIPTPGSCRCECNKGFQLD--------------------- 483
P + D C L+ LCQ+ CI T GS C C GF L
Sbjct: 601 PGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP 659
Query: 484 -LRGECIDV------------DECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRD 530
L+ E V + C+ N C GS C C GY C D
Sbjct: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCED 719
Query: 531 IDECLQNGRICNNGR-CINTDGSFHCV-----CNAGFHVTRDGKNCEDMDEC-SIRNMCL 583
DECL C+ + C+NT GSF+CV C G+ + + C D++EC + + C
Sbjct: 720 QDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGY-ILNAHRKCVDINECVTDLHTCS 778
Query: 584 NG-MCINEDGSFKC----ICKPGFQLASDGRYCKDINECET-PGICMNG-RCVNTDGSYR 636
G C+N GSF C C+PG+ L DG C+D++EC C G C NT GS+
Sbjct: 779 RGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFY 836
Query: 637 CE----CFPGLAVGLDGRVCVD----THMRSTCYGGYKRGQCIKPLFGAVTKSECCCAST 688
C+ C G +G CVD T + C G+ CI + G+ T
Sbjct: 837 CQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGF---SCINTV-GSYT--------- 882
Query: 689 EYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS---DINECALDPDICPNG-ICENLRG 744
CQ P +C+ G + G+ D+NEC C G +C NL G
Sbjct: 883 -------CQRNP--------LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPG 927
Query: 745 TYKCICNSGYEVDSTGKNCVDINECVLN-SLLCDNGQCRNTPGSFVCTCPKGFIYKPDLK 803
+Y+C C +G++ D+ G+ C+D+NEC + LC + C NT GS+ C+C GF+ D K
Sbjct: 928 SYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGK 986
Query: 804 TCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCE 863
CED++ECE+ C + C N GS+ C C L C T ID E
Sbjct: 987 RCEDVNECEAQRC-SQECANIYGSYQCYCRQGYQLAEDGHTC----------TDID---E 1032
Query: 864 ININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYS-RIKGTQCEDIDECEVFPGVCK 922
L + C ++ ++ C +GY+ G C+D+DEC + C
Sbjct: 1033 CAQGAGILCTFRCLNVPGSYQCACP--------EQGYTMTANGRSCKDVDECALGTHNCS 1084
Query: 923 NG-LCVNTRGSFKC---QCP 938
C N +GSF+C +CP
Sbjct: 1085 EAETCHNIQGSFRCLRFECP 1104
Score = 200 bits (509), Expect = 1e-50
Identities = 145/436 (33%), Positives = 202/436 (46%), Gaps = 76/436 (17%)
Query: 451 DYCQLVRYLCQNGR-CIPTPGSCRCE-----CNKGFQLDLRGECIDVDEC--EKNPCAGG 502
D C + + C + C+ T GS C C G+ L+ +C+D++EC + + C+ G
Sbjct: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRG 780
Query: 503 E-CINNQGSYTCQ----CRAGYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHCV 556
E C+N GS+ C C GY L EC D+DEC C G C NT GSF+C
Sbjct: 781 EHCVNTLGSFHCYKALTCEPGY--ALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 838
Query: 557 ----CNAGFHVTRDGKNCEDMDEC-SIRNMCLNGM-CINEDGSFKC-----ICKPGFQLA 605
C GF +G NC D++EC S+ C G CIN GS+ C IC G+ +
Sbjct: 839 ARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHAS 897
Query: 606 SDGRYCKDINECETPGI--CMNGR-CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCY 662
DG C D+NECET G+ C G+ C N GSYRC+C G GR C+D +
Sbjct: 898 DDGTKCVDVNECET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE----- 951
Query: 663 GGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS 722
C AS G CQ Y+ C+SG + + G
Sbjct: 952 ---------------------CWASP----GRLCQHTCENTLGSYRCSCASGFLLAADGK 986
Query: 723 ---DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNG 779
D+NEC + C C N+ G+Y+C C GY++ G C DI+EC + +
Sbjct: 987 RCEDVNEC--EAQRCSQE-CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTF 1043
Query: 780 QCRNTPGSFVCTCP-KGFIYKPDLKTCEDIDECE--SSPCING-VCKNSPGSFIC---EC 832
+C N PGS+ C CP +G+ + ++C+D+DEC + C C N GSF C EC
Sbjct: 1044 RCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFEC 1103
Query: 833 SSESTLDPTKTICIET 848
+ + +KT C T
Sbjct: 1104 -PPNYVQVSKTKCERT 1118
Score = 182 bits (461), Expect = 5e-45
Identities = 162/614 (26%), Positives = 226/614 (36%), Gaps = 149/614 (24%)
Query: 571 EDMDECSIR--NMCLNGMCINEDGSFKCICKPGFQLASDGRYCK---------------- 612
+D DEC + +C + +CIN GS+ C C PGF L DGR C+
Sbjct: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
Query: 613 -----------------DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDT 655
N C+ G C C GS C CFPG A+ DG C D
Sbjct: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQV-CSTVGGSAICSCFPGYAIMADGVSCED- 719
Query: 656 HMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGP 715
+ C G C + F T C + + LC+ G
Sbjct: 720 --QDECLMGAH--DCSRRQFCVNTLGSFYCVN-------------------HTVLCADGY 756
Query: 716 GMTSAGS--DINECALDPDICPNGI-CENLRGTYKCI----CNSGYEVDSTGKNCVDINE 768
+ + DINEC D C G C N G++ C C GY + C D++E
Sbjct: 757 ILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG--ECEDVDE 814
Query: 769 CVLNSLLCDNG-QCRNTPGSFVCT----CPKGFIYKPDLKTCEDIDECES--SPCINGV- 820
C + + C G C+NT GSF C C GF+ P+ C DI+EC S PC G
Sbjct: 815 CAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE-GNCVDINECTSLSEPCRPGFS 873
Query: 821 CKNSPGSFICE-----CSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 875
C N+ GS+ C+ C+ T C++ CE ++ + Q
Sbjct: 874 CINTVGSYTCQRNPLICARGYHASDDGTKCVDV-----------NECETGVHRCG-EGQV 921
Query: 876 CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKC 935
C +L ++ C G+G C D++EC PG C NT GS++C
Sbjct: 922 CHNLPGSYRCDCKAGFQRDAFGRG--------CIDVNECWASPGRLCQHTCENTLGSYRC 973
Query: 936 QCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEE 995
C SG L A G+ C D+ E + C+ A + C C G E+
Sbjct: 974 SCASGFLLAADGKRCEDVN------ECEAQRCSQECANIYGSYQCYCRQGYQL-AEDGHT 1026
Query: 996 CPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRC 1055
C DI+EC + +C N GS++C C
Sbjct: 1027 C------------------------------TDIDECAQGAGILCTFRCLNVPGSYQCAC 1056
Query: 1056 -DSGFALDSEERNCTDIDECRISPDLCGRGQ-CVNTPGDFEC---KCDEGY---ESGFMM 1107
+ G+ + + R+C D+DEC + C + C N G F C +C Y
Sbjct: 1057 PEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCE 1116
Query: 1108 MKNCMDIDECQRDP 1121
C D ECQ P
Sbjct: 1117 RTTCHDFLECQNSP 1130
Score = 122 bits (305), Expect = 7e-27
Identities = 70/171 (40%), Positives = 90/171 (52%), Gaps = 13/171 (7%)
Query: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECEKNPCAGGECINNQGSYTCQCRA 517
LCQ+ C T GS RC C GF L G+ C DV+ECE C+ EC N GSY C CR
Sbjct: 959 LCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQ-ECANIYGSYQCYCRQ 1016
Query: 518 GYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVC-NAGFHVTRDGKNCEDMDEC 576
GYQ C DIDEC Q I RC+N GS+ C C G+ +T +G++C+D+DEC
Sbjct: 1017 GYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDEC 1076
Query: 577 SI--RNMCLNGMCINEDGSFKCI---CKPGFQLAS----DGRYCKDINECE 618
++ N C N GSF+C+ C P + S + C D EC+
Sbjct: 1077 ALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1127
Score = 97.4 bits (241), Expect = 2e-19
Identities = 91/332 (27%), Positives = 125/332 (37%), Gaps = 53/332 (15%)
Query: 67 CCPGWKTLPGGNQCIVPICRHSC--GDGFCSRPNMCTCPSGQI-----APSCGSRSIQHC 119
C PG+ + G C + C G CSR C G C I +
Sbjct: 704 CFPGYAIMADGVSCED---QDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNA 760
Query: 120 NIRCMNGGSCSDDHCLCQKGY-----IGT-HCGQPV-CESG-CLNGGRCVAPNRCA---- 167
+ +C++ C D C +G +G+ HC + + CE G L G C + CA
Sbjct: 761 HRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTH 820
Query: 168 -CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGR--AWGHPCE-- 222
C GF C+ T F + Q C + G + C + + PC
Sbjct: 821 TCQPGFL---CQN---TKGSFYCQARQRC---MDGFLQDPEGNCVDINECTSLSEPCRPG 871
Query: 223 ----------MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFEC 271
C P C RG+ + C DV+EC+ C +G C N GS+ C
Sbjct: 872 FSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRC 931
Query: 272 KCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331
C AG + + + C D++EC PG C NT+ SY C C GF + DG RC DV
Sbjct: 932 DCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDV 991
Query: 332 RPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
C RCS + QC C G
Sbjct: 992 NE--CEAQ----RCSQECANIYGSYQCYCRQG 1017
Score = 89.0 bits (219), Expect = 6e-17
Identities = 86/268 (32%), Positives = 102/268 (38%), Gaps = 56/268 (20%)
Query: 86 RHSCGDGFCSRP-------NMCTCPSGQIAP--SC----GSRSIQHCNIRCMNGGSCSDD 132
R C DGF P N CT S P SC GS + Q + C G SDD
Sbjct: 840 RQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 899
Query: 133 HCLCQKGYIGTHCGQP-VCESG---CLNGGRC---VAPNRCACTYGFTGPQCERDYRTGP 185
GT C CE+G C G C RC C GF +RD
Sbjct: 900 ---------GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF-----QRDAFGRG 945
Query: 186 CFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH-PCRRGFIPNIRTGAC 244
C V C A+ GR H CE C GF+ C
Sbjct: 946 CIDVNE-----------------CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRC 988
Query: 245 QDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC 304
+DV+EC+A C C N GS++C C G++L E C DIDEC+ GI C
Sbjct: 989 EDVNECEA--QRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC 1045
Query: 305 TNTVSSYFCKCPPGFYT-SPDGTRCIDV 331
N SY C CP YT + +G C DV
Sbjct: 1046 LNVPGSYQCACPEQGYTMTANGRSCKDV 1073
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 249 bits (636), Expect = 3e-65
Identities = 305/1253 (24%), Positives = 461/1253 (36%), Gaps = 273/1253 (21%)
Query: 533 ECLQNGRICNNGRCINTDGS--FHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCIN- 589
E L + +G+C++ S + C C F GK C+++D CS + NG CIN
Sbjct: 176 ESLSSEFCSGHGKCLSEAWSKTYSCHCQPPF----SGKYCQELDACSFKPCKNNGSCINK 231
Query: 590 ----EDGSFKCICKPGFQLASDGRYCKD-INECETPGICMNGRCVN-TDGSYRCEC---F 640
++ +++C+C P F G+ C + I +C+ P +C +G C N T S+ CEC F
Sbjct: 232 RENWDEQAYECVCHPPF----TGKNCSEIIGQCQ-PHVCFHGNCSNITSNSFICECDEQF 286
Query: 641 PGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCP 700
G + + CV +KRG C
Sbjct: 287 SGPFCEVSAKPCVSLLF-------WKRGIC------------------------------ 309
Query: 701 AQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGI-CENLRGTYKCICNSGYEVDST 759
+S+ Y C G + +D++E +L P C NG C + CIC+ + T
Sbjct: 310 PNSSSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIF----T 363
Query: 760 GKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCED-IDECE--SSPC 816
C I + L +N C+ + C+C GF K CE ID C+ S C
Sbjct: 364 DLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTE----KNCEKAIDHCKLLSINC 419
Query: 817 INGV-CKNSPGSFICECSSESTLDPTKTICIE-TIKGTCW--QTVIDGRCEININGATLK 872
+N C N G F K +CI K CW + V + G T
Sbjct: 420 LNEEWCFNIIGRF-------------KYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFH 466
Query: 873 SQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVF--PGVCKNGLCVN-- 928
C G A Q + + G++ +G +C+ + + F ++ VN
Sbjct: 467 G-ICQDKGPA--------QFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDP 517
Query: 929 TRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEE----CTLPIAGRHRMDACCCSV 984
+ C P T + C +C + +E C L AG ++
Sbjct: 518 EDNNSSCWFPHEGTKEICANGC------SCLSEEDSQEYRYLCFLRWAGNMYLE------ 565
Query: 985 GAAWGTEECEECPMRNTPEYEELCP---RGPGFATKEITNGKPFFKDINECKMIPSLCTH 1041
T + +E N ++E +C P + G+ +++ C S+ H
Sbjct: 566 ----NTTDDQE----NECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVH 617
Query: 1042 GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRG-QCVNTPGDFECKCDEG 1100
G C S C C L ERN +ID C G + G F KC G
Sbjct: 618 GLCLAL--SHNCNCS---GLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPG 672
Query: 1101 YESGFMMMKNC-MDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQLSPNISACI---- 1154
++ C +DIDEC P C+ G C + G+Y C+C P ++ S C+
Sbjct: 673 FKG-----TQCEIDIDECASHP--CKNGATCIDQPGNYFCQCVPPFKVVDGFS-CLCNPG 724
Query: 1155 --------DINECELSAHLCP-NGRCVNLIGKYQCACNPGYHSTPDRLFC-VDIDECSIM 1204
DI++C L+A C N C +L YQC C + FC + +EC +
Sbjct: 725 YVGIRCEQDIDDCILNA--CEHNSTCKDLHLSYQCVCLSDWEGN----FCEQESNECKMN 778
Query: 1205 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC--TNIPGEYR 1262
+ CT+ SY C C G+ Q +I+EC+ +P +GG C + IPG++
Sbjct: 779 PCKNNSTCTDLYKSYRCECTSGWT---GQNCSEEINECDSDP-CMNGGLCHESTIPGQFV 834
Query: 1263 CLC---YDGFMASEDMKTC----------------VDVNE------------CDLNPNIC 1291
CLC Y G + C VD N+ C+++ C
Sbjct: 835 CLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDC 894
Query: 1292 L------SGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGS 1345
L G CE+ +F C C G+SG + +INEC + C + C +
Sbjct: 895 LFLSCQDYGDCEDMVNNFRCICRPGFSGSLCE---IEINEC--SSEPCKNNGTCVDLTNR 949
Query: 1346 FKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTC-TD 1404
F C+C P + G + D+++C C +C Y CLC GYT G C +
Sbjct: 950 FFCNCEPEYHGPFCE-LDVNKCK--ISPCLDEENCVYRTDGYNCLCAPGYT--GINCEIN 1004
Query: 1405 LDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNL 1464
LDEC L +G C++ Y C+C GF G CE L N C+ G C L
Sbjct: 1005 LDECLSEPCL-HDGVCIDGINHYTCDCKSGFF----GTHCETNANDCLSNPCLHGRCTEL 1059
Query: 1465 PGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTR 1523
+ C C + D + C +N+C G C + + C CP +
Sbjct: 1060 INEYPCSC----DADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGY------ 1109
Query: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS 1583
C I D E+ + C G C P +
Sbjct: 1110 ------TGAYCEKSI-------DNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQ 1156
Query: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDT 1643
+I +I+EC P L G C + + C+C G+
Sbjct: 1157 FCEI------------------NINECSSSPCL-HGADCEDHINGYVCKCQPGW----SG 1193
Query: 1644 RVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMD-MRRSLC 1695
C++ EC P C C TC+C P +M + G C D +RR C
Sbjct: 1194 HHCENELEC-IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
Score = 236 bits (601), Expect = 3e-61
Identities = 290/1200 (24%), Positives = 461/1200 (38%), Gaps = 242/1200 (20%)
Query: 1176 GKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRS 1235
G C + T + FC + +G + +Y C CQP F+ +
Sbjct: 155 GPSPCPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFS----GKY 210
Query: 1236 CTDIDECEDNPNICDGGQCTN-----IPGEYRCLCYDGFMASEDMKTCVD-VNECDLNPN 1289
C ++D C P + G C N Y C+C+ F K C + + +C P+
Sbjct: 211 CQELDACSFKP-CKNNGSCINKRENWDEQAYECVCHPPFTG----KNCSEIIGQC--QPH 263
Query: 1290 ICLSGTCEN-TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNC-----GKHAVCTNTA 1343
+C G C N T SFIC CD +SG CE+ A C K +C N++
Sbjct: 264 VCFHGNCSNITSNSFICECDEQFSGP----------FCEVSAKPCVSLLFWKRGICPNSS 313
Query: 1344 GSFKCSCSPGWIGDGIKCTDLDE-----CSNGTHMCSQHADCKNTMGSYRCLCKEGYTGD 1398
++ C G + TD+ E C NGT DC C+C +T
Sbjct: 314 SAYTYECPKGSSSQNGE-TDVSEFSLVPCQNGT-------DCIKISNDVMCICSPIFT-- 363
Query: 1399 GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACED-IDECSLPNICV 1457
C + E+ L N C Y C C GF K CE ID C L +I
Sbjct: 364 DLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTE----KNCEKAIDHCKLLSINC 419
Query: 1458 FGT--CHNLPGLFRCEC-----------------------------------------EI 1474
C N+ G F+ C E
Sbjct: 420 LNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEY 479
Query: 1475 GYELDRSGGNCTDVNECLDPTTCISGNC------VNTP-------------GSYIC---- 1511
++L +G +D ++ NC VN P IC
Sbjct: 480 VWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGC 539
Query: 1512 DCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGV--GVSKASCCCSL--- 1566
C + + R C +GN YL+ D+ + C +E +++ C CSL
Sbjct: 540 SCLSEEDSQEYRYLCFLRWAGNMYLE--NTTDDQENECQHEAVCKDEINRPRCSCSLSYI 597
Query: 1567 GKAWGTPCEMCPAVNTSEYKILC------PGGEGFRPNPITVILEDIDECQELPGLCQGG 1620
G+ + C ++ LC G + + D ++C+ C+ G
Sbjct: 598 GRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKS--ASCKNG 655
Query: 1621 -KCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYM 1679
+ G F +C G+ + T+ D++EC + TC + GNY C C P +
Sbjct: 656 TTSTHLRGYFFRKCVPGF---KGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFK 712
Query: 1680 QVNGGNNCMDMRRSLCYRNYYADNQTCD-GELLFNMTKKMCCCSYNIGRAWNKPCEQCPI 1738
V+G + LC Y D + + N C + N C+ +
Sbjct: 713 VVDGFS-------CLCNPGYVGIRCEQDIDDCILN------ACEH------NSTCKDLHL 753
Query: 1739 PSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCE-NGVCINMVGSFRCECPVGF 1797
+ +C S G + + +EC+ P C+ N C ++ S+RCEC G+
Sbjct: 754 ----SYQCVCLSDWEGNFCE------QESNECKMNP--CKNNSTCTDLYKSYRCECTSGW 801
Query: 1798 F---YNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ-CNDR-NE 1852
++++ C D D C NG +C + G + C C P Y TGQ C+ R N
Sbjct: 802 TGQNCSEEINEC-DSDPCMNGGLCHES----TIPGQFVCLCPPLY----TGQFCHQRYNL 852
Query: 1853 CQEIPNIC-SHGQCIDTV-GSFYCLCHTGFKTNDDQTMCLDINECERDACGN-GTCRNTI 1909
C + N C ++ C+ V + +C+C F+ + + +D+ +C +C + G C + +
Sbjct: 853 CDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE---IDVKDCLFLSCQDYGDCEDMV 909
Query: 1910 GSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR-NGQCINTVGSFQCQCNEGYEVAPDG 1968
+F C C GF S + I+++EC+S C+ NG C++ F C C Y G
Sbjct: 910 NNFRCICRPGF--SGSLCEIEINECSS---EPCKNNGTCVDLTNRFFCNCEPEYH----G 960
Query: 1969 RTC-VDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICAL 2026
C +D+N+C + P DG Y C+C PGY+ N CE ++DEC+ EP +
Sbjct: 961 PFCELDVNKCKISPCLDEENCVYRTDG-YNCLCAPGYTGIN--CEINLDECLSEPCLHD- 1016
Query: 2027 GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCA 2086
G C + + C C GF + D + C G+C+ E C+
Sbjct: 1017 GVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCL----HGRCT------ELINEYPCS 1066
Query: 2087 LKGEGWGDPCEL----CPTEP--DEAFRQICPYGSGIIVGPDDSAV----DMDECKEPD- 2135
+G C++ C + P +E F Q +G I + +D C EP+
Sbjct: 1067 CDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPEL 1126
Query: 2136 ---VCKHGQ-CINTDG-SYRCECPFGYILAGNEC-VDTDECSVGNPCGNGT-CKNVIGGF 2188
+C +G C++ G ++ C C G+ +G C ++ +ECS +PC +G C++ I G+
Sbjct: 1127 NSVICLNGGICVDGPGHTFDCRCLPGF--SGQFCEININECS-SSPCLHGADCEDHINGY 1183
Query: 2189 ECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDE 2248
C C+ G+ CE+ EC N + N GS C C G++ +C DE
Sbjct: 1184 VCKCQPGWSG---HHCENELECIPNSCVHELCMENEPGS-TCLCTPGFMTCSIGLLCGDE 1239
Score = 211 bits (538), Expect = 6e-54
Identities = 278/1126 (24%), Positives = 413/1126 (36%), Gaps = 293/1126 (26%)
Query: 1408 CSENLN---LCGNGQCLNAPGG--YRCECDMGFVPSADGKACEDIDECSLPNICVFGTCH 1462
C E+L+ G+G+CL+ Y C C P GK C+++D CS G+C
Sbjct: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQ----PPFSGKYCQELDACSFKPCKNNGSCI 229
Query: 1463 NL-----PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVN-TPGSYICDCPPD 1516
N + C C + +G NC+++ P C GNC N T S+IC+C
Sbjct: 230 NKRENWDEQAYECVCHPPF----TGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQ 285
Query: 1517 FELNPTRVG---CVDT---------RSGNCYLDIRPRGD---NGDTACSN------EIGV 1555
F V CV S + Y P+G NG+T S + G
Sbjct: 286 FSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGT 345
Query: 1556 GVSKAS----CCCS------LGKAWGTPCEMCPAVNTSEYKIL-----CPGGEGFRPNPI 1600
K S C CS L K+ T CE P N + K C GF
Sbjct: 346 DCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNC 405
Query: 1601 TVILEDIDECQELPGLCQGGK-CINTFGSFQCRCPTG------YYLNEDTRVCDDVNECE 1653
+ ID C+ L C + C N G F+ C G ++L + + C
Sbjct: 406 E---KAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCG 462
Query: 1654 TP--GIC---GPGT----------------CYNTVGNYTCI---CPPDYMQVN------- 1682
GIC GP C + Y + C D VN
Sbjct: 463 VTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNS 522
Query: 1683 --------------GGNNCMDMRRSLCYR---------NYYADNQTCDGE--------LL 1711
G +C+ S YR N Y +N T D E
Sbjct: 523 SCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCK 582
Query: 1712 FNMTKKMCCCSYN-IGRAWNKPCEQCPIPSTDEFATLC----------GSQRPGFVIDIY 1760
+ + C CS + IGR + C + LC G QR I
Sbjct: 583 DEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNI--- 639
Query: 1761 TGLPVDIDECREIPGVCENGVC-INMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGPVC 1818
+D ++C+ C+NG ++ G F +C GF K CE DIDEC + P C
Sbjct: 640 --CEIDTEDCKSAS--CKNGTTSTHLRGYFFRKCVPGF----KGTQCEIDIDECASHP-C 690
Query: 1819 QRNAECINTAGSYRCDCKPGYRFTSTGQC------------NDRNECQEIPNICSHGQ-C 1865
+ A CI+ G+Y C C P ++ C D ++C I N C H C
Sbjct: 691 KNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDC--ILNACEHNSTC 748
Query: 1866 IDTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC-GNGTCRNTIGSFNCRCNHGFILSH 1924
D S+ C+C + ++ N + + NEC+ + C N TC + S+ C C G+ +
Sbjct: 749 KDLHLSYQCVCLSDWEGNFCEQ---ESNECKMNPCKNNSTCTDLYKSYRCECTSGW--TG 803
Query: 1925 NNDCIDVDECASG---NGNLCR-------------------------------------N 1944
N +++EC S NG LC N
Sbjct: 804 QNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNN 863
Query: 1945 GQCINTVGSFQ-CQCNEGYEVAPDGRTC-VDINECLLEPRKCAP-GTCQNLDGSYRCICP 2001
C+ V + Q C C E +E G+ C +D+ +CL C G C+++ ++RCIC
Sbjct: 864 STCLALVDANQHCICREEFE----GKNCEIDVKDCLF--LSCQDYGDCEDMVNNFRCICR 917
Query: 2002 PGYSLQNEKCE-DIDECVEEPEICA-LGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMS 2059
PG+S CE +I+EC EP C GTC + F C C + G C+
Sbjct: 918 PGFS--GSLCEIEINECSSEP--CKNNGTCVDLTNRFFCNCEPEY----HGPFCE----- 964
Query: 2060 YCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIV 2119
+ KC + C + +G+ C P +GI
Sbjct: 965 -----LDVNKCKISPCLDEEN----CVYRTDGYNCLC--------------APGYTGI-- 999
Query: 2120 GPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNG 2179
+ +++DEC G CI+ Y C+C G+ G C + NPC +G
Sbjct: 1000 ---NCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFF--GTHCETNANDCLSNPCLHG 1054
Query: 2180 TCKNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVGYVL 2238
C +I + C+C+ G C+ IN+C P + C + + C CP GY
Sbjct: 1055 RCTELINEYPCSCD---ADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYT- 1110
Query: 2239 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGY----QRRP--DGEGC-VD 2291
CE+ +C E ++ + +C+ GPG+ + P G+ C ++
Sbjct: 1111 ---------GAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEIN 1161
Query: 2292 ENECQTKPGICENGR-CLNTRGSYTCECNDGFTA--SPNQDECLDN 2334
NEC + P C +G C + Y C+C G++ N+ EC+ N
Sbjct: 1162 INECSSSP--CLHGADCEDHINGYVCKCQPGWSGHHCENELECIPN 1205
Score = 207 bits (526), Expect = 2e-52
Identities = 272/1078 (25%), Positives = 401/1078 (37%), Gaps = 250/1078 (23%)
Query: 1779 NGVCINMVGS--FRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGS-----Y 1831
+G C++ S + C C F C+++D C P C+ N CIN + Y
Sbjct: 186 HGKCLSEAWSKTYSCHCQPPFSGK----YCQELDACSFKP-CKNNGSCINKRENWDEQAY 240
Query: 1832 RCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCID-TVGSFYCLCHTGFK---TNDDQT 1887
C C P FT +CQ P++C HG C + T SF C C F
Sbjct: 241 ECVCHPP--FTGKNCSEIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 1888 MCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNG-Q 1946
C+ + +R G C N+ ++ C G S N DV E + C+NG
Sbjct: 297 PCVSLLFWKR-----GICPNSSSAYTYECPKGS--SSQNGETDVSEFSLVP---CQNGTD 346
Query: 1947 CINTVGSFQCQCNEGYEVAPDGRTCVDIN-ECLLEPRKCAPGTCQNLDGSYRCICPPGYS 2005
CI C C+ + C I C P + TC+ + Y C C G++
Sbjct: 347 CIKISNDVMCICSPIFT----DLLCKSIQTSCESFPLR-NNATCKKCEKDYPCSCISGFT 401
Query: 2006 LQNEKCED-IDECVEEPEICALGT-CSNTEGSFK-------------------------C 2038
+N CE ID C C C N G FK C
Sbjct: 402 EKN--CEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLC 459
Query: 2039 LCPEGFS-------------------LSSSGRRCQDLRMSYCYAKF----EGGKCSSPKS 2075
C F S G +CQ + +Y + + + P+
Sbjct: 460 YCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPED 519
Query: 2076 RNHSKQECCCALKGEGWGDPCE---LCPTEPD-EAFRQICPYGSGIIVGPDDSAVDMD-E 2130
N S C EG + C C +E D + +R +C + +++ D + E
Sbjct: 520 NNSS-----CWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENE 574
Query: 2131 CKEPDVCK----------------------------------HGQCINTDGSYRCECPFG 2156
C+ VCK HG C+ S+ C C
Sbjct: 575 CQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLAL--SHNCNCSGL 632
Query: 2157 YILAGNEC-VDTDECSVGNPCGNGTCKNVIGG-FECTCEEGFEPGPMMTCE-DINECAQN 2213
N C +DT++C + C NGT + G F C GF+ CE DI+ECA +
Sbjct: 633 QRYERNICEIDTEDCKSAS-CKNGTTSTHLRGYFFRKCVPGFKG---TQCEIDIDECASH 688
Query: 2214 PLLCAFRCVNTYGSYECKC-PVGYVLREDRRMCKDED---ECEEGKHDCT----EKQMEC 2265
P C++ G+Y C+C P V+ +C CE+ DC E C
Sbjct: 689 PCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTC 748
Query: 2266 KNLIGTYMCICGPGYQRRPDGEGCVDE-NECQTKPGICENGR-CLNTRGSYTCECNDGFT 2323
K+L +Y C+C ++ G C E NEC+ P C+N C + SY CEC G+T
Sbjct: 749 KDLHLSYQCVCLSDWE----GNFCEQESNECKMNP--CKNNSTCTDLYKSYRCECTSGWT 802
Query: 2324 ASP--------NQDECLDN-------------------------REGYCFTEVLQNMCQI 2350
+ D C++ + Y ++L N C+
Sbjct: 803 GQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRN 862
Query: 2351 GSSNRNPVTKSECCCDGGRGWGPHCEI---------CPFQGTVA-----FKKLCPHGRGF 2396
S+ V ++ C G +CEI C G F+ +C G
Sbjct: 863 NSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSG 922
Query: 2397 MTNGADIDECKVIHDVCRN-GECVNDRGSYHCICKTGYTPDITGTSC-VDLNECNQAPKP 2454
+I+EC + C+N G CV+ + C C+ P+ G C +D+N+C +P
Sbjct: 923 SLCEIEINECS--SEPCKNNGTCVDLTNRFFCNCE----PEYHGPFCELDVNKCKISPCL 976
Query: 2455 CNFICKNTEGSYQCSCPKGYILQEDGRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPP 2513
C Y C C GY G +C+ +LDEC ++ +C++ I +TC C
Sbjct: 977 DEENCVYRTDGYNCLCAPGYT----GINCEINLDECLSEPCLHDGVCIDGINHYTCDCKS 1032
Query: 2514 GFTQHHTSCIDN-NECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDEC 2571
GF H C N N+C S+ L G C + C C D T + C+ +++C
Sbjct: 1033 GFFGTH--CETNANDCLSNPCLHGR---CTELINEYPCSCDA----DGTSTQCKIKINDC 1083
Query: 2572 EGNHRCQHG-CQNIIGGYRCSCPQGYLQHY---QWNQCVDENE----CLSAHICGGASCH 2623
G CQ G+ C CP+GY Y + C + CL+ IC H
Sbjct: 1084 TSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGH 1143
Query: 2624 NTLGSYKCMCPAGFQYEQFSGGCQ-DINECGSAQAPCSYG--CSNTEGGYLCGCPPGY 2678
++ C C GF QF C+ +INEC S+ PC +G C + GY+C C PG+
Sbjct: 1144 ----TFDCRCLPGFS-GQF---CEININECSSS--PCLHGADCEDHINGYVCKCQPGW 1191
Score = 206 bits (523), Expect = 3e-52
Identities = 258/1010 (25%), Positives = 400/1010 (39%), Gaps = 183/1010 (18%)
Query: 461 QNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGG-ECINNQGSYTCQCRAGY 519
+ G C + + EC KG GE DV E PC G +CI C C +
Sbjct: 305 KRGICPNSSSAYTYECPKGSSSQ-NGET-DVSEFSLVPCQNGTDCIKISNDVMCICSPIF 362
Query: 520 QSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCED-MDECSI 578
L C+ I ++ + NN C + + C C +GF KNCE +D C +
Sbjct: 363 TDLL----CKSIQTSCESFPLRNNATCKKCEKDYPCSCISGF----TEKNCEKAIDHCKL 414
Query: 579 RNM-CLNG-MCINEDGSFK------CICKPGFQLASDGRYCKDINECETPGICMNGRCVN 630
++ CLN C N G FK C P + L + + + C G+ +G C +
Sbjct: 415 LSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYC---GVTFHGICQD 471
Query: 631 TDGSYRCECFPGLA-VGLDGRVC---VDTH--MRSTCYGGY--------KRGQCIKPLFG 676
G + E L G +G C +D + + + C C P G
Sbjct: 472 K-GPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEG 530
Query: 677 A--VTKSECCCASTEYAFGEPCQPC---------------PAQNSAEYQALCS---SGPG 716
+ + C C S E + E C +N +++A+C + P
Sbjct: 531 TKEICANGCSCLSEEDS-QEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPR 589
Query: 717 MTSAGSDINE-CALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLL 775
+ + S I C ++ D C ++ G C+ S + + +G + N C +++
Sbjct: 590 CSCSLSYIGRLCVVNVDYCLGNHSISVHGL--CLALS-HNCNCSGLQRYERNICEIDTED 646
Query: 776 CDNGQCRNTPGSFVCTCPKGFIYK---PDLK--TCE-DIDECESSPCINGV-CKNSPGSF 828
C + C+N S T +G+ ++ P K CE DIDEC S PC NG C + PG++
Sbjct: 647 CKSASCKNGTTS---THLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNY 703
Query: 829 ICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKS----QCCSSLGAAWG 884
C+C + P K + + C + RCE +I+ L + C L ++
Sbjct: 704 FCQC-----VPPFKVV--DGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQ 756
Query: 885 SPCTLCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVCKNG-LCVNTRGSFKCQCPSGMT 942
C S +G CE + +EC++ P CKN C + S++C+C SG T
Sbjct: 757 CVCL------------SDWEGNFCEQESNECKMNP--CKNNSTCTDLYKSYRCECTSGWT 802
Query: 943 LDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEE----C-- 996
+ + C E T+P C C + + C + C
Sbjct: 803 GQNCSEEINECDSDPCMNGGLCHESTIP-----GQFVCLCP--PLYTGQFCHQRYNLCDL 855
Query: 997 ---PMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKC 1053
P RN L +E GK D+ +C + S +G C + + +F+C
Sbjct: 856 LHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFL-SCQDYGDCEDMVNNFRC 914
Query: 1054 RCDSGFALDSEERNCTDIDECRISPDLC-GRGQCVNTPGDFECKCDEGYESGFMMMKNCM 1112
C GF+ E +I+EC P C G CV+ F C C+ Y F +
Sbjct: 915 ICRPGFSGSLCE---IEINECSSEP--CKNNGTCVDLTNRFFCNCEPEYHGPFCEL---- 965
Query: 1113 DIDECQRDPLLCRGGVCHNTEGSYRCECPPGH-------QLSPNIS-------ACID-IN 1157
D+++C+ P L + T+G Y C C PG+ L +S CID IN
Sbjct: 966 DVNKCKISPCLDEENCVYRTDG-YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGIN 1024
Query: 1158 E-------------CELSAH-----LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDID 1199
CE +A+ C +GRC LI +Y C+C+ ST ++ D
Sbjct: 1025 HYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCT 1084
Query: 1200 ECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIP 1258
MN G FC S + C C G+ ++S + E E N IC +GG C + P
Sbjct: 1085 SIPCMNEG---FCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGP 1141
Query: 1259 GE-YRCLCYDGFMASEDMKTC-VDVNECDLNPNICLSGT-CENTKGSFICHCDMGYSGKK 1315
G + C C GF + C +++NEC +P CL G CE+ ++C C G+SG
Sbjct: 1142 GHTFDCRCLPGFSG----QFCEININECSSSP--CLHGADCEDHINGYVCKCQPGWSGHH 1195
Query: 1316 GKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTD 1363
+ NE E ++C H +C C C+PG++ G+ C D
Sbjct: 1196 CE------NELECIPNSC-VHELCMENEPGSTCLCTPGFMTCSIGLLCGD 1238
Score = 197 bits (502), Expect = 1e-49
Identities = 278/1127 (24%), Positives = 410/1127 (36%), Gaps = 276/1127 (24%)
Query: 967 CTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFF 1026
C P +G++ + CS C N E C P F GK
Sbjct: 202 CQPPFSGKYCQELDACSFKPCKNNGSCIN-KRENWDEQAYECVCHPPFT------GKNCS 254
Query: 1027 KDINECKMIPSLCTHGKCRN-TIGSFKCRCDSGFAL------------------------ 1061
+ I +C+ P +C HG C N T SF C CD F+
Sbjct: 255 EIIGQCQ--PHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNS 312
Query: 1062 -----------DSEERNCTDIDECRISPDLCGRG-QCVNTPGDFECKCDEGYESGFMMMK 1109
S + TD+ E + P C G C+ D C C + ++ K
Sbjct: 313 SSAYTYECPKGSSSQNGETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIFTD--LLCK 368
Query: 1110 NCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNG 1169
+ C+ PL C E Y C C G N ID C+L + C N
Sbjct: 369 SIQT--SCESFPLR-NNATCKKCEKDYPCSCISGFT-EKNCEKAID--HCKLLSINCLNE 422
Query: 1170 R-CVNLIGKYQ------CACNPGYHSTPDRLFCVDIDECSI-MNGGCETFCTNSEGSYEC 1221
C N+IG+++ C NP + L + C + +G C+ +E
Sbjct: 423 EWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQD---KGPAQFEY 479
Query: 1222 SCQPGFALMPDQR-------------SCTD----IDECEDNPNIC------------DGG 1252
Q GFA ++ +CT+ +++ EDN + C +G
Sbjct: 480 VWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGC 539
Query: 1253 QCTNIPG--EYRCLCYDGFMASEDMKTCVD--VNECDLNPNICLSGTCENTKGSFICHCD 1308
C + EYR LC+ + + ++ D NEC C++ C C
Sbjct: 540 SCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHE------AVCKDEINRPRCSCS 593
Query: 1309 MGYSGK------------------------KGKTGCTDI-----NECEIGAHNCGKHAVC 1339
+ Y G+ C+ + N CEI +C K A C
Sbjct: 594 LSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDC-KSASC 652
Query: 1340 ------TNTAGSFKCSCSPGWIGDGIKCT-DLDECSNGTHMCSQHADCKNTMGSYRCLCK 1392
T+ G F C PG+ G +C D+DEC++ H C A C + G+Y C C
Sbjct: 653 KNGTTSTHLRGYFFRKCVPGF--KGTQCEIDIDECAS--HPCKNGATCIDQPGNYFCQCV 708
Query: 1393 EGY-TGDGFTCT------------DLDECSENLNLCG-NGQCLNAPGGYRCECDMGFVPS 1438
+ DGF+C D+D+C LN C N C + Y+C C +
Sbjct: 709 PPFKVVDGFSCLCNPGYVGIRCEQDIDDCI--LNACEHNSTCKDLHLSYQCVC----LSD 762
Query: 1439 ADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD-VNECLDPTT 1496
+G CE + +EC + TC +L +RCEC G+ +G NC++ +NEC D
Sbjct: 763 WEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGW----TGQNCSEEINEC-DSDP 817
Query: 1497 CISGNCVNT---PGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEI 1553
C++G + PG ++C CPP + T C R C L P +N S +
Sbjct: 818 CMNGGLCHESTIPGQFVCLCPPLY----TGQFC-HQRYNLCDLLHNPCRNN-----STCL 867
Query: 1554 GVGVSKASCCCSLGKAWGTPCEM----CPAVNTSEY----------KILC-PGGEGFRPN 1598
+ + C C + G CE+ C ++ +Y + +C PG G
Sbjct: 868 ALVDANQHCICR-EEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSG---- 922
Query: 1599 PITVILEDIDECQELPGLCQG-GKCINTFGSFQCRCPTGYYLNEDTRVCD-DVNECETPG 1656
++ +I+EC P C+ G C++ F C C Y+ C+ DVN+C+
Sbjct: 923 --SLCEIEINECSSEP--CKNNGTCVDLTNRFFCNCEPEYH----GPFCELDVNKCKISP 974
Query: 1657 ICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYA----DNQTCDGELLF 1712
C Y C+C P Y +N N + C + ++ TCD + F
Sbjct: 975 CLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGF 1034
Query: 1713 NMTKKMCCCSYNIGRAWNKPC----------------------EQCPIPSTDEFAT---- 1746
T C N + PC QC I D +
Sbjct: 1035 FGTH----CETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMN 1090
Query: 1747 --LCGSQRPGFVIDI---YTGLPVD--IDECREIP---GVCENG-VCINMVG-SFRCECP 1794
C GF YTG + ID C E +C NG +C++ G +F C C
Sbjct: 1091 EGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCL 1150
Query: 1795 VGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNEC 1853
GF CE +I+EC + P C A+C + Y C C+PG+ S C + EC
Sbjct: 1151 PGFSGQ----FCEININECSSSP-CLHGADCEDHINGYVCKCQPGW---SGHHCENELEC 1202
Query: 1854 QEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC 1900
IPN C H C++ CLC GF T +C D E R C
Sbjct: 1203 --IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGD--EIRRITC 1245
Score = 195 bits (496), Expect = 5e-49
Identities = 278/1114 (24%), Positives = 409/1114 (36%), Gaps = 239/1114 (21%)
Query: 1605 EDIDECQELPGLCQGGKCIN-TFGSFQCRCPTGYYLNEDTRVCD-DVNECETPGICGPGT 1662
E I +CQ P +C G C N T SF C C + C+ C + G
Sbjct: 255 EIIGQCQ--PHVCFHGNCSNITSNSFICECDEQF----SGPFCEVSAKPCVSLLFWKRGI 308
Query: 1663 CYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCS 1722
C N+ YT CP NG + + C N T + + MC CS
Sbjct: 309 CPNSSSAYTYECPKGSSSQNGETDVSEFSLVPC------QNGT---DCIKISNDVMCICS 359
Query: 1723 YN----IGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVD--IDECREIPGV 1776
+ ++ CE P+ + + C P I +T + ID C+ +
Sbjct: 360 PIFTDLLCKSIQTSCESFPLRN-NATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSIN 418
Query: 1777 CENGV-CINMVGSFRCECPVG------FFYNDKLLVCEDIDEC---------QNGPVCQR 1820
C N C N++G F+ C G +F + L+ + + C GP
Sbjct: 419 CLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFE 478
Query: 1821 NAECINTAGSYRCDCK---PGYRF---------TSTGQCNDRNECQEIPN-----ICSHG 1863
+ AGS C+ Y F T D N P+ IC++G
Sbjct: 479 YVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANG 538
Query: 1864 -QCIDTVGS--FYCLCHTGF-------KTNDDQTMCLDINECERDACGNGTCRNTIGSFN 1913
C+ S + LC + T DDQ NEC+ +A C++ I
Sbjct: 539 CSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQE-----NECQHEA----VCKDEINRPR 589
Query: 1914 CRCNHGFILSHNNDCI-DVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCV 1972
C C+ +I C+ +VD C GN ++ +G C+ S C C+ G
Sbjct: 590 CSCSLSYI---GRLCVVNVDYCL-GNHSISVHGLCLAL--SHNCNCS--------GLQRY 635
Query: 1973 DINECLLEPRKCAPGTCQN------LDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICA 2025
+ N C ++ C +C+N L G + C PG+ + +CE DIDEC P C
Sbjct: 636 ERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGF--KGTQCEIDIDECASHP--CK 691
Query: 2026 LG-TCSNTEGSFKCLCP------EGFSLSSS----GRRC-QDLRMSYCYAKFEGGKCSSP 2073
G TC + G++ C C +GFS + G RC QD+ A C
Sbjct: 692 NGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDL 751
Query: 2074 KSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKE 2133
H +C C EG C E +E M+ CK
Sbjct: 752 ----HLSYQCVCLSDWEG-----NFCEQESNEC--------------------KMNPCKN 782
Query: 2134 PDVCKHGQCINTDGSYRCECPFGYILAG-----NECVDTDECSVGNPCGNGTCKNVIGGF 2188
+ C + SYRCEC G+ NEC D+D C G C T + G F
Sbjct: 783 -----NSTCTDLYKSYRCECTSGWTGQNCSEEINEC-DSDPCMNGGLCHEST---IPGQF 833
Query: 2189 ECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDE 2248
C C P+ T + C Q LC + C + V +C++E
Sbjct: 834 VCLCP------PLYTGQF---CHQRYNLCDLLHNPCRNNSTC---LALVDANQHCICREE 881
Query: 2249 DE---CEEGKHDCT----EKQMECKNLIGTYMCICGPGYQRRPDGEGC-VDENECQTKPG 2300
E CE DC + +C++++ + CIC PG+ G C ++ NEC ++P
Sbjct: 882 FEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFS----GSLCEIEINECSSEP- 936
Query: 2301 ICEN-GRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGS--SNRNP 2357
C+N G C++ + C C + F E+ N C+I N
Sbjct: 937 -CKNNGTCVDLTNRFFCNCEPEYHGP--------------FCELDVNKCKISPCLDEENC 981
Query: 2358 VTKSE---CCCDGGRGWGPHCEI---------CPFQGTVAF---KKLCPHGRGFMTNGAD 2402
V +++ C C G G +CEI C G C GF +
Sbjct: 982 VYRTDGYNCLCAPGYT-GINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCE 1040
Query: 2403 IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC-VDLNECNQAPKPCNFICKN 2461
+ + + C +G C Y C C D T T C + +N+C P C+
Sbjct: 1041 TNANDCLSNPCLHGRCTELINEYPCSCDA----DGTSTQCKIKINDCTSIPCMNEGFCQK 1096
Query: 2462 TEGSYQCSCPKGYILQEDGRSC-KDLDECATKQHNCQF-----LCVNTIGG-FTCKCPPG 2514
+ + C CP+GY G C K +D CA + N +CV+ G F C+C PG
Sbjct: 1097 SAHGFTCICPRGYT----GAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPG 1152
Query: 2515 FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGN 2574
F+ I+ NEC+S L G+ C++ + C+CQ G+S G CE+ EC N
Sbjct: 1153 FSGQFCE-ININECSSSPCLHGAD--CEDHINGYVCKCQPGWS----GHHCENELECIPN 1205
Query: 2575 HRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDE 2608
C G C C G++ C DE
Sbjct: 1206 SCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDE 1239
Score = 153 bits (386), Expect = 3e-36
Identities = 149/525 (28%), Positives = 210/525 (40%), Gaps = 90/525 (17%)
Query: 462 NGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINN--QGSYTCQCRAG 518
N C S RCEC G+ E +++EC+ +PC GG C + G + C C
Sbjct: 783 NSTCTDLYKSYRCECTSGWTGQNCSE--EINECDSDPCMNGGLCHESTIPGQFVCLCPPL 840
Query: 519 YQSTLTRTECRDIDECLQNGRICNNGRCIN-TDGSFHCVCNAGFHVTRDGKNCE-DMDEC 576
Y D L + NN C+ D + HC+C F +GKNCE D+ +C
Sbjct: 841 YTGQFCHQRYNLCD--LLHNPCRNNSTCLALVDANQHCICREEF----EGKNCEIDVKDC 894
Query: 577 SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNGRCVNTDGSY 635
+ G C + +F+CIC+PGF G C+ +INEC + NG CV+ +
Sbjct: 895 LFLSCQDYGDCEDMVNNFRCICRPGF----SGSLCEIEINECSSEPCKNNGTCVDLTNRF 950
Query: 636 RCECFP---GLAVGLDGRVCVDTHM--RSTCYGGYKRGQCI-KPLFGAVTKSECCCASTE 689
C C P G LD C + C C+ P + + C + +
Sbjct: 951 FCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGIN----CEINLD 1006
Query: 690 YAFGEPC--QPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYK 747
EPC Y C SG T ++ N+C +P C +G C L Y
Sbjct: 1007 ECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNP--CLHGRCTELINEYP 1064
Query: 748 CICNSGYEVDSTGKNC-VDINECVLNSLLCDN-GQCRNTPGSFVCTCPKGF---IYKPDL 802
C C + D T C + IN+C S+ C N G C+ + F C CP+G+ + +
Sbjct: 1065 CSC----DADGTSTQCKIKINDC--TSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSI 1118
Query: 803 KTCEDIDECESSPCIN-GVCKNSPG-SFICECSSESTLDPTKTICIETIKGTCWQTVIDG 860
C + E S C+N G+C + PG +F C C + G Q
Sbjct: 1119 DNCAE-PELNSVICLNGGICVDGPGHTFDCRC----------------LPGFSGQF---- 1157
Query: 861 RCEININGATLKSQCCSSLGAAWGSPCT------LCQVDPICGKGYSRIKGTQCEDIDEC 914
CEININ CSS G+ C +C+ C G+S G CE +E
Sbjct: 1158 -CEININE-------CSSSPCLHGADCEDHINGYVCK----CQPGWS---GHHCE--NEL 1200
Query: 915 EVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD-IRLETC 958
E P C + LC+ C C G + G +C D IR TC
Sbjct: 1201 ECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
Score = 118 bits (296), Expect = 7e-26
Identities = 135/552 (24%), Positives = 202/552 (36%), Gaps = 110/552 (19%)
Query: 63 YNAYCCPGWK---TLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 119
Y C W+ N+C + C+++ + C C SG +C S I C
Sbjct: 755 YQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNC-SEEINEC 813
Query: 120 NIR-CMNGGSCSDDH------CLCQKGYIGTHCGQ-----PVCESGCLNGGRCV----AP 163
+ CMNGG C + CLC Y G C Q + + C N C+ A
Sbjct: 814 DSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDAN 873
Query: 164 NRCACTYGFTGPQCERDYRT---------GPCFTVISN--QMCQGQLSGIVCTKTLCCAT 212
C C F G CE D + G C +++N +C+ SG +LC
Sbjct: 874 QHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSG-----SLCEIE 928
Query: 213 VGRAWGHPCEMCPAQPHPCRRGFI---PNIRTGACQ-DVDECQAIPGLCQGGNCINTVGS 268
+ PC+ R F P C+ DV++C+ P L + NC+
Sbjct: 929 INECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDE-ENCVYRTDG 987
Query: 269 FECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTR 327
+ C C G+ CE ++DEC + P + G C + ++ Y C C GF+ GT
Sbjct: 988 YNCLCAPGY----TGINCEINLDECLSEPCL-HDGVCIDGINHYTCDCKSGFF----GTH 1038
Query: 328 CIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNK 387
C +GRC+ + I + C CDA C I+ N
Sbjct: 1039 CETNANDCLSNPCLHGRCT----ELINEYPCSCDADG--------TSTQCKIK----IND 1082
Query: 388 LCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPV 447
S+P + G + I P G+ Y S
Sbjct: 1083 CTSIPCMNEGFCQKSAHGFTCI-----CPRGYTGA-----------YCEKS--------- 1117
Query: 448 NVTDYC---QLVRYLCQNGR-CIPTPG-SCRCECNKGFQLDLRGEC-IDVDECEKNPCA- 500
D C +L +C NG C+ PG + C C GF C I+++EC +PC
Sbjct: 1118 --IDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQF---CEININECSSSPCLH 1172
Query: 501 GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAG 560
G +C ++ Y C+C+ G+ C + EC+ N C + C+ + C+C G
Sbjct: 1173 GADCEDHINGYVCKCQPGWSG----HHCENELECIPNS--CVHELCMENEPGSTCLCTPG 1226
Query: 561 FHVTRDGKNCED 572
F G C D
Sbjct: 1227 FMTCSIGLLCGD 1238
Score = 115 bits (288), Expect = 6e-25
Identities = 182/723 (25%), Positives = 270/723 (37%), Gaps = 195/723 (26%)
Query: 2111 CPYGSGIIVGPDDSAVDMDECKEP---DVCK-HGQCINTDGS--YRCEC--PFGYILAGN 2162
CP G + V V C+E + C HG+C++ S Y C C PF +G
Sbjct: 159 CPLGLRLNV-----TVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPF----SGK 209
Query: 2163 ECVDTDECSVGNPC-GNGTCKNV-----IGGFECTCEEGFEPGPMMTCEDINECAQNPLL 2216
C + D CS PC NG+C N +EC C F C +I Q +
Sbjct: 210 YCQELDACSF-KPCKNNGSCINKRENWDEQAYECVCHPPFTG---KNCSEIIGQCQPHVC 265
Query: 2217 CAFRCVN-TYGSYECKC--------------PVGYVLREDRRMCKDED-----EC----- 2251
C N T S+ C+C P +L R +C + EC
Sbjct: 266 FHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSS 325
Query: 2252 -EEGKHDCTEKQM-------ECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE 2303
+ G+ D +E + +C + MCIC P + D + C++ P +
Sbjct: 326 SQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIF---TDLLCKSIQTSCESFP-LRN 381
Query: 2304 NGRCLNTRGSYTCECNDGFTASPNQDECLDN---------REGYCFTEV--LQNMCQIGS 2352
N C Y C C GFT N ++ +D+ E +CF + + +C I
Sbjct: 382 NATCKKCEKDYPCSCISGFT-EKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVC-IPG 439
Query: 2353 SNRNP------------------VTKSECCCDGGRG-----W-----GPHCEICPFQGTV 2384
+NP VT C D G W G E C QG +
Sbjct: 440 CTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKC--QGVI 497
Query: 2385 -AFKKL---CPHGRGFMTNGADID-ECKVIH----DVCRNG-ECVNDRGS----YHCICK 2430
A+ L C ++ + D + C H ++C NG C+++ S Y C +
Sbjct: 498 DAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLR 557
Query: 2431 TGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYI--------------- 2475
+ T+ NEC +CK+ +CSC YI
Sbjct: 558 WAGNMYLENTTDDQENECQH-----EAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNH 612
Query: 2476 -------------------LQEDGRSCKDLDECATKQHNCQFLCVNT--IGGFTCKCPPG 2514
LQ R+ ++D K +C+ +T G F KC PG
Sbjct: 613 SISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPG 672
Query: 2515 FTQHHTSC-IDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSL----------DQTGS 2563
F T C ID +EC S + C + C + PG++ C+C F + G
Sbjct: 673 F--KGTQCEIDIDECAS--HPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGI 728
Query: 2564 SCE-DVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCVDE-NECLSAHICGG 2619
CE D+D+C N C+H C+++ Y+C C L ++ N C E NEC
Sbjct: 729 RCEQDIDDCILN-ACEHNSTCKDLHLSYQCVC----LSDWEGNFCEQESNECKMNPCKNN 783
Query: 2620 ASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG--C--SNTEGGYLCGCP 2675
++C + SY+C C +G+ + S ++INEC S PC G C S G ++C CP
Sbjct: 784 STCTDLYKSYRCECTSGWTGQNCS---EEINECDS--DPCMNGGLCHESTIPGQFVCLCP 838
Query: 2676 PGY 2678
P Y
Sbjct: 839 PLY 841
Score = 93.2 bits (230), Expect = 3e-18
Identities = 143/602 (23%), Positives = 218/602 (36%), Gaps = 129/602 (21%)
Query: 2131 CKEPDVCK------HGQCINT-----DGSYRCEC--PFGYILAGNECVDTDECSVGNPCG 2177
C+E D C +G CIN + +Y C C PF G C + + C
Sbjct: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPF----TGKNCSEIIGQCQPHVCF 266
Query: 2178 NGTCKNVIGG-FECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVG 2235
+G C N+ F C C+E F GP CE C C N+ +Y +CP G
Sbjct: 267 HGNCSNITSNSFICECDEQFS-GPF--CEVSAKPCVSLLFWKRGICPNSSSAYTYECPKG 323
Query: 2236 YVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENEC 2295
+ + D E C + +C + MCIC P + D + C
Sbjct: 324 SSSQNG-----ETDVSEFSLVPC-QNGTDCIKISNDVMCICSPIFT---DLLCKSIQTSC 374
Query: 2296 QTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDN---------REGYCFTEV--L 2344
++ P + N C Y C C GFT N ++ +D+ E +CF +
Sbjct: 375 ESFP-LRNNATCKKCEKDYPCSCISGFTEK-NCEKAIDHCKLLSINCLNEEWCFNIIGRF 432
Query: 2345 QNMCQIGSSNRNP--------VTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGF 2396
+ +C I +NP + C G G IC +G F+ + G
Sbjct: 433 KYVC-IPGCTKNPCWFLKNVYLIHQHLCYCGVTFHG----ICQDKGPAQFEYVWQLGFA- 486
Query: 2397 MTNGADIDECKVIHDVC--RNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKP 2454
G++ ++C+ + D C D + P+ +SC +E +
Sbjct: 487 ---GSEGEKCQGVIDAYFFLAANCTEDATYVN-------DPEDNNSSCWFPHEGTKE--- 533
Query: 2455 CNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPG 2514
IC N CSC + +ED + + +LC G
Sbjct: 534 ---ICANG-----CSC----LSEEDSQEYR-------------YLCFLRWAG-------- 560
Query: 2515 FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEG 2573
+ + D+ E N C + +C++ C C SL G C +VD C G
Sbjct: 561 -NMYLENTTDDQE-----NECQHEAVCKDEINRPRCSC----SLSYIGRLCVVNVDYCLG 610
Query: 2574 NHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQC-VDENECLSAHICGGASCHNTLGSYKCM 2632
NH + + C+C LQ Y+ N C +D +C SA G + + G +
Sbjct: 611 NHSISVHGLCLALSHNCNCSG--LQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRK 668
Query: 2633 CPAGFQYEQFSGGCQ-DINECGSAQAPCSYG--CSNTEGGYLCGCPPGYFRIGQGHCVSG 2689
C GF+ Q C+ DI+EC S PC G C + G Y C C P + + C+
Sbjct: 669 CVPGFKGTQ----CEIDIDECASH--PCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCN 722
Query: 2690 MG 2691
G
Sbjct: 723 PG 724
Score = 86.7 bits (213), Expect = 3e-16
Identities = 64/211 (30%), Positives = 95/211 (45%), Gaps = 25/211 (11%)
Query: 460 CQNGRCIPTPGSCRCECNKGFQLDLRGEC-IDVDECEKNPCAG-GECINNQGSYTCQCRA 517
C +GRC C C+ +C I +++C PC G C + +TC C
Sbjct: 1051 CLHGRCTELINEYPCSCDAD---GTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPR 1107
Query: 518 GYQSTLTRTECRDIDECLQ---NGRIC-NNGRCINTDG-SFHCVCNAGFHVTRDGKNCE- 571
GY + ID C + N IC N G C++ G +F C C GF G+ CE
Sbjct: 1108 GYTGAYCE---KSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGF----SGQFCEI 1160
Query: 572 DMDECSIRNMCLNGM-CINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVN 630
+++ECS + CL+G C + + C C+PG+ G +C++ EC P C++ C+
Sbjct: 1161 NINECS-SSPCLHGADCEDHINGYVCKCQPGWS----GHHCENELEC-IPNSCVHELCME 1214
Query: 631 TDGSYRCECFPGLAVGLDGRVCVDTHMRSTC 661
+ C C PG G +C D R TC
Sbjct: 1215 NEPGSTCLCTPGFMTCSIGLLCGDEIRRITC 1245
Score = 78.6 bits (192), Expect = 8e-14
Identities = 74/294 (25%), Positives = 109/294 (37%), Gaps = 48/294 (16%)
Query: 63 YNAYCCPGWKTLP---GGNQCIVPICRHS--CGDGFCSRPNMCTCPSGQIAPSCGSRSIQ 117
YN C PG+ + ++C+ C H C DG C C SG C + +
Sbjct: 988 YNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGI--NHYTCDCKSGFFGTHCETNAND 1045
Query: 118 HCNIRCMNGGSC---SDDHCLCQKGYIGTHCGQPV--CES-GCLNGGRCVAPNR---CAC 168
+ C++G ++ C C T C + C S C+N G C C C
Sbjct: 1046 CLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCIC 1105
Query: 169 TYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQP 228
G+TG CE+ + + +L+ ++C G C P
Sbjct: 1106 PRGYTGAYCEKSI----------DNCAEPELNSVICLN-----------GGICVDGPGHT 1144
Query: 229 HPCRRGFIPNIRTGACQ-DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCE 287
CR +P C+ +++EC + P L G +C + + + CKC G CE
Sbjct: 1145 FDCR--CLPGFSGQFCEININECSSSPCL-HGADCEDHINGYVCKCQPGWS----GHHCE 1197
Query: 288 DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCID-VRPGYCYTAL 340
+ EC IP C C C C PGF T G C D +R C T +
Sbjct: 1198 NELEC--IPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPI 1249
Score = 58.5 bits (140), Expect = 9e-08
Identities = 88/381 (23%), Positives = 125/381 (32%), Gaps = 112/381 (29%)
Query: 67 CCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNG 126
C PG+K G QC + I C C C G C + ++G
Sbjct: 669 CVPGFK----GTQCEIDI--DECASHPCKNGATCIDQPGNYFCQCVPP------FKVVDG 716
Query: 127 GSCSDDHCLCQKGYIGTHCGQPV-------CE---------------------------- 151
SC LC GY+G C Q + CE
Sbjct: 717 FSC-----LCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQE 771
Query: 152 ------SGCLNGGRCV---APNRCACTYGFTGPQCERDYRTGPCFTVISNQMC-QGQLSG 201
+ C N C RC CT G+TG C + ++ +C + + G
Sbjct: 772 SNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPG 831
Query: 202 -IVCTKTLCCAT-VGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQ-------------- 245
VC LC G+ +C +PCR A Q
Sbjct: 832 QFVC---LCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCE 888
Query: 246 -DVDECQAIPGLCQG-GNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICE-G 301
DV +C + CQ G+C + V +F C C G CE +I+ECS+ P C+
Sbjct: 889 IDVKDCLFLS--CQDYGDCEDMVNNFRCICRPGFS----GSLCEIEINECSSEP--CKNN 940
Query: 302 GECTNTVSSYFCKCPPGFY------------TSP--DGTRCIDVRPGY---CYTALTNGR 344
G C + + +FC C P ++ SP D C+ GY C T
Sbjct: 941 GTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGIN 1000
Query: 345 CSNQLPQSITKMQCCCDAGRC 365
C L + ++ + C G C
Sbjct: 1001 CEINLDECLS--EPCLHDGVC 1019
Score = 45.4 bits (106), Expect = 8e-04
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 5/86 (5%)
Query: 1313 GKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTH 1372
G KG + D + G + C CT +F C C P W G+ C C N +
Sbjct: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN--TCNQSVSCLN--N 2919
Query: 1373 MCSQHADC-KNTMGSYRCLCKEGYTG 1397
+C + C + SY CLC G+ G
Sbjct: 2920 LCLHQSLCIPDQSFSYSCLCTLGWVG 2945
Score = 45.1 bits (105), Expect = 0.001
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 15/79 (18%)
Query: 114 RSIQHCNIR------CMNGGSCSDDH----CLCQKGYIGTHCGQPVCESG-CLNGGRCVA 162
++I++C++ C N G+C D+ C C + Y G C CE+ C NG CV
Sbjct: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVP 2388
Query: 163 PNR----CACTYGFTGPQC 177
+ C C YG +GP C
Sbjct: 2389 KSGTDIVCLCPYGRSGPLC 2407
Score = 43.1 bits (100), Expect = 0.004
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 1333 CGKHAVCTNTAGSFKCSCSPGWIGDGIKCTD----LDECSNGTHMCSQHADCKNTMGSYR 1388
CG C + S C+C+ GW G CT+ D + H CS+ A C + Y
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGW--KGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYT 2676
Query: 1389 CLCKEGYTG 1397
C C G TG
Sbjct: 2677 CFCPLGTTG 2685
Score = 41.6 bits (96), Expect = 0.011
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 6/61 (9%)
Query: 1619 GGKCINTFGSFQCRCPTGY---YLNEDTRVCDDVNECETPGICGPG-TCYNTVGNYTCIC 1674
GG CI + S C C TG+ + E CD E + P C G TC + YTC C
Sbjct: 2622 GGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP--EHDPPHHCSRGATCISLPHGYTCFC 2679
Query: 1675 P 1675
P
Sbjct: 2680 P 2680
Score = 40.4 bits (93), Expect = 0.025
Identities = 57/259 (22%), Positives = 83/259 (32%), Gaps = 73/259 (28%)
Query: 85 CRHSCGDGFCSRPNMCTCPSGQIAPSCGSR---------SIQHCNIR-CMNGGSCSDDH- 133
C+ S FCS C + SC + + C+ + C N GSC +
Sbjct: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE 233
Query: 134 --------CLCQKGYIGTHCGQPV--CESGCLNGGRC--VAPNR--CACTYGFTGPQCER 179
C+C + G +C + + C+ G C + N C C F+GP CE
Sbjct: 234 NWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEV 293
Query: 180 DYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNI 239
+ PC +++ K C A+ + C + +
Sbjct: 294 SAK--PCVSLLF-------------WKRGICPNSSSAYTYECPKGSSSQN---------- 328
Query: 240 RTGACQDVDECQAIPGLCQGG-NCINTVGSFECKC-PAGHKL----------------NE 281
DV E +P CQ G +CI C C P L N
Sbjct: 329 ---GETDVSEFSLVP--CQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNA 383
Query: 282 VSQKCEDIDECSTIPGICE 300
+KCE CS I G E
Sbjct: 384 TCKKCEKDYPCSCISGFTE 402
Score = 39.3 bits (90), Expect = 0.057
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 11/68 (16%)
Query: 2535 CGSKGICQNTPGSFTCECQRGFSLDQTGSSC-EDVDECEGN----HRCQHG--CQNIIGG 2587
CG+ G C + S C C G+ GS C E V C+ H C G C ++ G
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDPEHDPPHHCSRGATCISLPHG 2674
Query: 2588 YRCSCPQG 2595
Y C CP G
Sbjct: 2675 YTCFCPLG 2682
Score = 38.1 bits (87), Expect = 0.13
Identities = 42/158 (26%), Positives = 61/158 (38%), Gaps = 31/158 (19%)
Query: 1891 DINECERDACGNGTCRN----TIG--SFNCRCNHGFILSHNNDCIDVDECASGNGNLC-R 1943
++ +C+ ACG TCRN T+ +F+CRC + N C C + NLC
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWA---GNTCNQSVSCLN---NLCLH 2923
Query: 1944 NGQCI-NTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPP 2002
CI + S+ C C G+ GR C K + T + + SY P
Sbjct: 2924 QSLCIPDQSFSYSCLCTLGWV----GRYC---------ENKTSFSTAKFMGNSYIKYIDP 2970
Query: 2003 GYSLQNEKCEDI----DECVEEPEICALGTCSNTEGSF 2036
Y ++N + I E I +G N E F
Sbjct: 2971 NYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDF 3008
Score = 37.4 bits (85), Expect = 0.22
Identities = 43/182 (23%), Positives = 63/182 (34%), Gaps = 40/182 (21%)
Query: 145 CGQPVCESGCLNGGRCVAPN-----RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQL 199
C + + C G+C++ C C F+G C+ S + C+
Sbjct: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-------LDACSFKPCKNNG 226
Query: 200 SGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQG 259
S C W C P P + + +CQ P +C
Sbjct: 227 S---------CINKRENWDEQAYECVCHP--------PFTGKNCSEIIGQCQ--PHVCFH 267
Query: 260 GNCIN-TVGSFECKCPAGHK--LNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCP 316
GNC N T SF C+C EVS K C ++ + G C N+ S+Y +CP
Sbjct: 268 GNCSNITSNSFICECDEQFSGPFCEVSAK-----PCVSLL-FWKRGICPNSSSAYTYECP 321
Query: 317 PG 318
G
Sbjct: 322 KG 323
Score = 37.4 bits (85), Expect = 0.22
Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 12/88 (13%)
Query: 1924 HNNDCIDVDECASGNGNL--CRNG-QCINTVGSFQCQCNEGYEVAPDGRTCVD-INECLL 1979
H N V +C + +L C NG CI + S C C G++ G C + ++ C
Sbjct: 2599 HPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDP 2654
Query: 1980 E---PRKCAPG-TCQNLDGSYRCICPPG 2003
E P C+ G TC +L Y C CP G
Sbjct: 2655 EHDPPHHCSRGATCISLPHGYTCFCPLG 2682
Score = 37.0 bits (84), Expect = 0.28
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 10/66 (15%)
Query: 123 CMNGGSCSDD----HCLCQKGYIGTHCGQPVC--ESGCLNGGRCVAPNR----CACTYGF 172
C NGG C+ + C C + G C Q V + CL+ C+ C CT G+
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGW 2943
Query: 173 TGPQCE 178
G CE
Sbjct: 2944 VGRYCE 2949
Score = 36.2 bits (82), Expect = 0.48
Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 10/88 (11%)
Query: 102 CPSGQIAPSCGSRSIQHCNIRCMNGGSC----SDDHCLCQKGYIGTHCG--QPVCESGCL 155
CP G + + + + + C NG C +D C+C + C Q CES L
Sbjct: 320 CPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPL 379
Query: 156 NGG----RCVAPNRCACTYGFTGPQCER 179
+C C+C GFT CE+
Sbjct: 380 RNNATCKKCEKDYPCSCISGFTEKNCEK 407
Score = 36.2 bits (82), Expect = 0.48
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 1/66 (1%)
Query: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD-GGQCTNIPG 1259
CS+M G C S S C+C G+ + + D D P+ C G C ++P
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 1260 EYRCLC 1265
Y C C
Sbjct: 2674 GYTCFC 2679
Score = 35.8 bits (81), Expect = 0.63
Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 5/87 (5%)
Query: 237 PNIRTGACQDVDECQAIPGLCQ----GGNCINTVGSFECKCPAGHKLNEVSQKCEDIDEC 292
P A + V +C A P GG CI + S C C G K + ++ D
Sbjct: 2596 PEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE 2655
Query: 293 STIPGIC-EGGECTNTVSSYFCKCPPG 318
P C G C + Y C CP G
Sbjct: 2656 HDPPHHCSRGATCISLPHGYTCFCPLG 2682
Score = 35.8 bits (81), Expect = 0.63
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 14/90 (15%)
Query: 486 GECIDVDECEKNPCA-GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRIC-NN 543
G+C D C N C GGEC N +++C+C + C CL N +C +
Sbjct: 2872 GDC-DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAG----NTCNQSVSCLNN--LCLHQ 2924
Query: 544 GRCI-NTDGSFHCVCNAGFHVTRDGKNCED 572
CI + S+ C+C G+ G+ CE+
Sbjct: 2925 SLCIPDQSFSYSCLCTLGW----VGRYCEN 2950
Score = 35.4 bits (80), Expect = 0.82
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 7/69 (10%)
Query: 458 YLCQN-GRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQGS-YTCQ 514
+LC+N G CI + CEC + + G+ CE NPC G C+ G+ C
Sbjct: 2342 HLCRNNGTCISDNENLFCECPRLYS----GKLCQFASCENNPCGNGATCVPKSGTDIVCL 2397
Query: 515 CRAGYQSTL 523
C G L
Sbjct: 2398 CPYGRSGPL 2406
Score = 35.4 bits (80), Expect = 0.82
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 12/84 (14%)
Query: 1281 VNECDLNPNICLS----GTCENTKGSFICHCDMGYSGKKGKTGCTD-INECEIG---AHN 1332
V +C +P + GTC + S C+C G+ G + CT+ ++ C+ H+
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKG----SFCTETVSTCDPEHDPPHH 2661
Query: 1333 CGKHAVCTNTAGSFKCSCSPGWIG 1356
C + A C + + C C G G
Sbjct: 2662 CSRGATCISLPHGYTCFCPLGTTG 2685
Score = 35.4 bits (80), Expect = 0.82
Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 7/77 (9%)
Query: 491 VDECEKNPCA------GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNG 544
V +C +PC+ GG CI + S C C G++ + D C+ G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 545 -RCINTDGSFHCVCNAG 560
CI+ + C C G
Sbjct: 2666 ATCISLPHGYTCFCPLG 2682
Score = 35.0 bits (79), Expect = 1.1
Identities = 29/84 (34%), Positives = 37/84 (44%), Gaps = 12/84 (14%)
Query: 2127 DMDECKEPDVCKH-----GQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNG-T 2180
+++ C P H G CI+ + + CECP Y +G C C NPCGNG T
Sbjct: 2330 NIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLY--SGKLC-QFASCE-NNPCGNGAT 2385
Query: 2181 CKNVIG-GFECTCEEGFEPGPMMT 2203
C G C C G GP+ T
Sbjct: 2386 CVPKSGTDIVCLCPYG-RSGPLCT 2408
Score = 34.3 bits (77), Expect = 1.8
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 453 CQLVRYLCQNG-RCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNP---CA-GGECINN 507
C L++ C NG CI + S C C G++ E + + E +P C+ G CI+
Sbjct: 2614 CSLMK--CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
Query: 508 QGSYTCQCRAG 518
YTC C G
Sbjct: 2672 PHGYTCFCPLG 2682
Score = 34.3 bits (77), Expect = 1.8
Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 6/89 (6%)
Query: 1358 GIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGN 1417
G D D + G + C +C ++ C C + G+ TC C NL L +
Sbjct: 2868 GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN--TCNQSVSCLNNLCLHQS 2925
Query: 1418 GQCLNAPGGYRCECDMGFVPSADGKACED 1446
+ Y C C +G+V G+ CE+
Sbjct: 2926 LCIPDQSFSYSCLCTLGWV----GRYCEN 2950
Score = 33.9 bits (76), Expect = 2.4
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 14/92 (15%)
Query: 2399 NGADIDECKV---IHDVCRN-GECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKP 2454
+G +I+ C V H +CRN G C++D + C C Y+ + + + N C
Sbjct: 2327 HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGA-- 2384
Query: 2455 CNFICKNTEGS-YQCSCPKGYILQEDGRSCKD 2485
C G+ C CP G G C D
Sbjct: 2385 ---TCVPKSGTDIVCLCPYG----RSGPLCTD 2409
Score = 33.5 bits (75), Expect = 3.1
Identities = 42/209 (20%), Positives = 65/209 (31%), Gaps = 39/209 (18%)
Query: 79 QCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCL--- 135
QC +C H S +C C P C + ++ G C +
Sbjct: 259 QCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTY 318
Query: 136 -CQKGYIGTHCGQPVCESG---CLNGGRCVAPNR---CACTYGFTGPQCERDYRTGPCFT 188
C KG + V E C NG C+ + C C+ FT C+ + F
Sbjct: 319 ECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFP 378
Query: 189 VISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVD 248
+ +N C+ C K C+ + CE + +D
Sbjct: 379 LRNNATCK------KCEKDYPCSCISGFTEKNCE----------------------KAID 410
Query: 249 ECQAIPGLCQGGN-CINTVGSFECKCPAG 276
C+ + C C N +G F+ C G
Sbjct: 411 HCKLLSINCLNEEWCFNIIGRFKYVCIPG 439
Score = 33.5 bits (75), Expect = 3.1
Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 7/65 (10%)
Query: 1818 CQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSH-GQCI-DTVGSFYCL 1875
C+ EC ++ C C P + + CN C + N+C H CI D S+ CL
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDW---AGNTCNQSVSC--LNNLCLHQSLCIPDQSFSYSCL 2938
Query: 1876 CHTGF 1880
C G+
Sbjct: 2939 CTLGW 2943
Score = 33.1 bits (74), Expect = 4.1
Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 7/106 (6%)
Query: 1393 EGYTGDGFTCTDLDECSENLNLCGNG-QCLNAPGGYRCECDMGFVPSADGKACEDID-EC 1450
EG+ G + +L CGNG C+ + C C G+ S + D E
Sbjct: 2597 EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH 2656
Query: 1451 SLPNICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPT 1495
P+ C G TC +LP + C C +G +G C DP+
Sbjct: 2657 DPPHHCSRGATCISLPHGYTCFCPLG----TTGIYCEQALSISDPS 2698
Score = 33.1 bits (74), Expect = 4.1
Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 10/71 (14%)
Query: 1450 CSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT-----CISG-NCV 1503
CSL GTC C C G++ G CT+ DP C G C+
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWK----GSFCTETVSTCDPEHDPPHHCSRGATCI 2669
Query: 1504 NTPGSYICDCP 1514
+ P Y C CP
Sbjct: 2670 SLPHGYTCFCP 2680
Score = 32.7 bits (73), Expect = 5.3
Identities = 22/78 (28%), Positives = 30/78 (38%), Gaps = 6/78 (7%)
Query: 1071 IDECRISPDL---CGRG-QCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC-R 1125
+ +C SP CG G C+ + C C G++ F + D P C R
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCT-ETVSTCDPEHDPPHHCSR 2664
Query: 1126 GGVCHNTEGSYRCECPPG 1143
G C + Y C CP G
Sbjct: 2665 GATCISLPHGYTCFCPLG 2682
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 245 bits (626), Expect = 4e-64
Identities = 184/579 (31%), Positives = 254/579 (43%), Gaps = 97/579 (16%)
Query: 1005 EELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSE 1064
E C G AT + P+ + EC+M+ C H + + C +G +L +E
Sbjct: 34 EACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLE------ELHCATGISLANE 87
Query: 1065 ERNC------------TDIDECRISPDLCGRGQCVNTPG-DFECKCDEGYESGFMMMKNC 1111
+ C T + C C G+ G E GY+ G + C
Sbjct: 88 QDRCATPHGDNASLEATFVKRC---CHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACC 144
Query: 1112 --------------------MDIDECQRDPLL---CRGG-----VCHNTEGSYRCECPPG 1143
++++E Q DP L CRGG C +T C C G
Sbjct: 145 VKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVG 204
Query: 1144 HQLSPNISACIDINECELSAHLCPNGR-CVNLIGKYQC----ACNPGYHSTPDRLFCVDI 1198
+QL + +C D+NEC +H C G C+N +G ++C +C GY T D C DI
Sbjct: 205 YQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDI 263
Query: 1199 DECSIMNGGC--ETFCTNSEGSYEC----SCQPGFALMPDQRSCTDIDECEDNPNICD-G 1251
DEC C + C N+ GS+ C C+ GF + +C DI+EC C G
Sbjct: 264 DECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF-IQDALGNCIDINECLSISAPCPIG 322
Query: 1252 GQCTNIPGEYRCL-----CYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFIC 1305
C N G Y C C G+ +E+ CVDV+EC C G C N+ GSF C
Sbjct: 323 HTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRC 382
Query: 1306 HCDMGYSGKKGKTGCTDINECE-IGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCT 1362
C GY C D+NEC+ CG C NT GS+ CSCS G+ DG C
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCE 440
Query: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY---TGDGFTCTDLDECS--ENLNLCGN 1417
D++ECS+ CSQ +C N GSY+C C+ GY DG TC D+DEC+ ++C +
Sbjct: 441 DINECSSSP--CSQ--ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-S 495
Query: 1418 GQCLNAPGGYRCEC-DMGFVPSADGKACEDIDEC--SLPNICVFGTCHNLPGLFRC---E 1471
+C+N PG ++C C G+ + +G+ C+DIDEC + N + TC N+ G FRC E
Sbjct: 496 YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFE 555
Query: 1472 CEIGYELDRSGGNC----TDVNECLDPTTCISGNCVNTP 1506
C Y RS TD C+ CV P
Sbjct: 556 CPENYR--RSAATLQQEKTDTVRCIKSCRPNDVTCVFDP 592
Score = 227 bits (579), Expect = 1e-58
Identities = 148/418 (35%), Positives = 204/418 (48%), Gaps = 48/418 (11%)
Query: 1085 QCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCE---- 1139
QC +T + C C GY+ +C D++EC CR G C NT GS+RC+
Sbjct: 189 QCRDTGDEVVCSCFVGYQL-LSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSS 247
Query: 1140 CPPGHQLSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCA----CNPGYHSTPDRLF 1194
C G++L+ + ++C DI+ECE H C P+ C N +G ++C C G+ D L
Sbjct: 248 CGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF--IQDALG 304
Query: 1195 -CVDIDECSIMNGGCET--FCTNSEGSYEC-----SCQPGFALMPDQRSCTDIDECEDNP 1246
C+DI+EC ++ C C N+EGSY C +C G+ L + C D+DEC
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 1247 NICDGG-QCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFIC 1305
C G +C N PG +RC C G+ + CVDVNEC P CENT GS++C
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLC 424
Query: 1306 HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW---IGDGIKCT 1362
C +G+ C DINEC + C + C N GS++C C G+ DG+ C
Sbjct: 425 SCSVGFRLSVDGRSCEDINEC--SSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 1363 DLDECS--NGTHMCSQHADCKNTMGSYRCLC-KEGY--TGDGFTCTDLDECSENLNLCG- 1416
D+DEC+ G H+CS C N GS++C C GY +G C D+DEC ++ C
Sbjct: 481 DIDECALPTGGHICSYR--CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 1417 NGQCLNAPGGYRC---ECDMGFVPSADGKACEDID-----ECSLPN--ICVFGTCHNL 1464
N C N GG+RC EC + SA E D + PN CVF H +
Sbjct: 539 NETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTI 596
Score = 218 bits (555), Expect = 7e-56
Identities = 180/611 (29%), Positives = 246/611 (40%), Gaps = 116/611 (18%)
Query: 1121 PLLCRGGVCHNTEGS-----YRCECPPGHQLSPNISAC-----IDINECELSAHLCPNGR 1170
PLL GG+ G C GH+++ + C + EC + C
Sbjct: 13 PLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQC---- 68
Query: 1171 CVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALM 1230
C + + + CA + DR D S+ + C C C G A
Sbjct: 69 CHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCC-------HC-CLLGRAAQ 120
Query: 1231 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASE-------DMKTCVDVNE 1283
+SC ++ G QC + +R C + + ++V E
Sbjct: 121 AQGQSC--------EYSLMVGYQCGQV---FRACCVKSQETGDLDVGGLQETDKIIEVEE 169
Query: 1284 CDLNPNI---CLSG-----TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK 1335
+P + C G C +T +C C +GY C D+NEC G+H+C
Sbjct: 170 EQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRL 229
Query: 1336 HAVCTNTAGSFKC----SCSPGW-IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL 1390
C NT GSF+C SC G+ + + C D+DEC +G H C C+NT+GS+RC
Sbjct: 230 GESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCR 289
Query: 1391 ----CKEGYTGDGF-TCTDLDECSENLNLCGNGQ-CLNAPGGYRCE-----CDMGFVPSA 1439
CK G+ D C D++EC C G C+N G Y C+ C G+ +
Sbjct: 290 PKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNE 349
Query: 1440 DGKACEDIDECSLP-NICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTT 1496
+G C D+DEC+ P C G C N PG FRCEC+ GY D C DVNEC P
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
C NT GSY+C C F L+ C D + + CS E
Sbjct: 410 LCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN------------ECSSSPCSQECANV 457
Query: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPG- 1615
C C G Y++ G V EDIDEC G
Sbjct: 458 YGSYQCYCRRG-----------------YQLSDVDG---------VTCEDIDECALPTGG 491
Query: 1616 -LCQGGKCINTFGSFQCRCP-TGYYLNEDTRVCDDVNECETPGI--CGPG-TCYNTVGNY 1670
+C +CIN GSFQC CP +GY L + R C D++EC T GI C TC+N G +
Sbjct: 492 HICSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVT-GIHNCSINETCFNIQGGF 549
Query: 1671 TCI---CPPDY 1678
C+ CP +Y
Sbjct: 550 RCLAFECPENY 560
Score = 213 bits (542), Expect = 2e-54
Identities = 156/479 (32%), Positives = 219/479 (45%), Gaps = 71/479 (14%)
Query: 1109 KNCMDIDE----CQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAH 1164
K C + E Q + L C G+ E RC P G +A ++ + H
Sbjct: 59 KECRMVQEQCCHSQLEELHCATGISLANEQD-RCATPHGD------NASLEATFVKRCCH 111
Query: 1165 LCPNGRCVNLIGK---------YQC-----AC----------NPGYHSTPDRLFCVDID- 1199
C GR G+ YQC AC + G D++ V+ +
Sbjct: 112 CCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ 171
Query: 1200 ECSIMN------GGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD-GG 1252
E +N G C+ C ++ CSC G+ L+ D SC D++EC + C G
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGE 231
Query: 1253 QCTNIPGEYRC----LCYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFIC-- 1305
C N G +RC C G+ +ED +C D++EC+ + CL C+NT GSF C
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRP 290
Query: 1306 --HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-----SCSPGW--IG 1356
C G+ + C DINEC + C C NT GS+ C +C G+
Sbjct: 291 KLQCKSGFI-QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNE 349
Query: 1357 DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFT--CTDLDECSENL-N 1413
+G +C D+DEC+ C + C N+ GS+RC CK GY DG + C D++EC
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECE 1473
LCG+ +C N G Y C C +GF S DG++CEDI+ECS + C N+ G ++C C
Sbjct: 410 LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCR 466
Query: 1474 IGYEL-DRSGGNCTDVNECLDPT--TCISGNCVNTPGSYICDCPPD-FELNPTRVGCVD 1528
GY+L D G C D++EC PT S C+N PGS+ C CP + L P C D
Sbjct: 467 RGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQD 525
Score = 208 bits (530), Expect = 5e-53
Identities = 145/408 (35%), Positives = 189/408 (46%), Gaps = 56/408 (13%)
Query: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
G C+ +C +T C C G+ + C D E C T + C++G S N V
Sbjct: 184 GPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNE--CITG--SHSCRLGESCINTVG 238
Query: 2360 KSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKV-IHDVCRNGEC 2418
C D G G + C DIDEC+ IH+ + C
Sbjct: 239 SFRCQRDSSCGTGYE---------LTEDNSCK----------DIDECESGIHNCLPDFIC 279
Query: 2419 VNDRGSYHCI----CKTGYTPDITGTSCVDLNECNQ--APKPCNFICKNTEGSYQC---- 2468
N GS+ C CK+G+ D G +C+D+NEC AP P C NTEGSY C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 2469 -SCPKGYILQEDGRSCKDLDECATKQHNCQ--FLCVNTIGGFTCKCPPGFTQHHTS--CI 2523
+C +GY L E+G C D+DECA C CVN+ G F C+C G+ S C+
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 2524 DNNECTS-DINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQ 2582
D NEC LCG K C+NT GS+ C C GF L G SCED++EC + C C
Sbjct: 399 DVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQECA 455
Query: 2583 NIIGGYRCSCPQGY-LQHYQWNQCVDENECL---SAHICGGASCHNTLGSYKCMCPA-GF 2637
N+ G Y+C C +GY L C D +EC HIC C N GS++C CP+ G+
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCSCPSSGY 514
Query: 2638 QYEQFSGGCQDINECGSAQAPCSYG--CSNTEGGYLC---GCPPGYFR 2680
+ CQDI+EC + CS C N +GG+ C CP Y R
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRR 562
Score = 207 bits (528), Expect = 9e-53
Identities = 140/441 (31%), Positives = 192/441 (43%), Gaps = 62/441 (14%)
Query: 2168 DECSVGNPCGNGTCKNVIGGFECTCEEGFEP-GPMMTCEDINECAQNPLLCAF--RCVNT 2224
D C G PC C++ C+C G++ ++CED+NEC C C+NT
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2225 YGSYECK----CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI----C 2276
GS+ C+ C GY L ED CKD DECE G H+C + C+N +G++ C C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFI-CQNTLGSFRCRPKLQC 294
Query: 2277 GPGYQRRPDGEGCVDENECQTKPGICENGR-CLNTRGSYTCE-----CNDGFTASPNQDE 2330
G+ + G C+D NEC + C G C+NT GSYTC+ C G+ +
Sbjct: 295 KSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 2331 CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLC 2390
C+D E C C G N C C G + +C
Sbjct: 354 CVDVDE--CAPPA--EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC------------ 397
Query: 2391 PHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQ 2450
D++EC+ +C N GSY C C G+ + G SC D+NEC+
Sbjct: 398 ----------VDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 2451 APKPCNFICKNTEGSYQCSCPKGYILQE-DGRSCKDLDECA--TKQHNCQFLCVNTIGGF 2507
+P C+ C N GSYQC C +GY L + DG +C+D+DECA T H C + C+N G F
Sbjct: 448 SP--CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSF 505
Query: 2508 TCKCPPG---FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC---ECQRGFSLDQT 2561
C CP + +C D +EC + I+ C C N G F C EC +
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAA 565
Query: 2562 GSSCEDVDECEGNHRCQHGCQ 2582
E D RC C+
Sbjct: 566 TLQQEKTDTV----RCIKSCR 582
Score = 198 bits (503), Expect = 7e-50
Identities = 126/379 (33%), Positives = 176/379 (46%), Gaps = 48/379 (12%)
Query: 2349 QIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA---DIDE 2405
++ +P C RG GP + C G C G +++G D++E
Sbjct: 166 EVEEEQEDPYLNDRC-----RGGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNE 219
Query: 2406 CKVIHDVCRNGE-CVNDRGSYHC----ICKTGYTPDIT-GTSCVDLNECNQAPKPC--NF 2457
C CR GE C+N GS+ C C TGY ++T SC D++EC C +F
Sbjct: 220 CITGSHSCRLGESCINTVGSFRCQRDSSCGTGY--ELTEDNSCKDIDECESGIHNCLPDF 277
Query: 2458 ICKNTEGSYQC----SCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCK- 2510
IC+NT GS++C C G+I G +C D++EC + C C+NT G +TC+
Sbjct: 278 ICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQK 336
Query: 2511 ----CPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSS 2564
C G+ + T C+D +EC CG C N+PGSF CEC+ G+ D
Sbjct: 337 NVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM 396
Query: 2565 CEDVDECE--GNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASC 2622
C DV+EC+ C H C+N +G Y CSC G+ C D NEC S+ C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC--SQEC 454
Query: 2623 HNTLGSYKCMCPAGFQYEQFSG-GCQDINECG--SAQAPCSYGCSNTEGGYLCGCPPGYF 2679
N GSY+C C G+Q G C+DI+EC + CSY C N G + C CP +
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Query: 2680 RIGQG--------HCVSGM 2690
R+ CV+G+
Sbjct: 515 RLAPNGRNCQDIDECVTGI 533
Score = 196 bits (497), Expect = 4e-49
Identities = 174/601 (28%), Positives = 243/601 (40%), Gaps = 120/601 (19%)
Query: 1958 CNEGYEVAPDGRTC-----VDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE 2012
C +G+ +A + C + EC + +C + L C G SL NE+
Sbjct: 37 CADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELH------CATGISLANEQ-- 88
Query: 2013 DIDECVEEPEICALGTCSNTEGSF--KCL--CPEGFSLSSSGRRCQDLRMSYCYAKFEGG 2068
D C G ++ E +F +C C G + + G+ C+ Y+ G
Sbjct: 89 --DRCATPH-----GDNASLEATFVKRCCHCCLLGRAAQAQGQSCE-------YSLMVGY 134
Query: 2069 KCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDM 2128
+C C +K + GD E D+ + +
Sbjct: 135 QCGQVFR--------ACCVKSQETGDLDVGGLQETDKIIE---------VEEEQEDPYLN 177
Query: 2129 DECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGN-PCGNG-TCKNV 2184
D C+ CK QC +T C C GY L G C D +EC G+ C G +C N
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2185 IGGFEC----TCEEGFEPGPMMTCEDINECAQNPLLCA--FRCVNTYGSYECK----CPV 2234
+G F C +C G+E +C+DI+EC C F C NT GS+ C+ C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 2235 GYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI-----CGPGYQRRPDGEGC 2289
G++ ++ C D +EC C C N G+Y C CG GY +G C
Sbjct: 297 GFI-QDALGNCIDINECLSISAPCPIGHT-CINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 2290 VDENECQTKPGICENG-RCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMC 2348
VD +EC C G RC+N+ GS+ CEC G+ + + + MC
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY-----------------YFDGISRMC 397
Query: 2349 QIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG-----ADI 2403
V +EC GR G CE LC GF + DI
Sbjct: 398 ---------VDVNECQRYPGRLCGHKCE------NTLGSYLCSCSVGFRLSVDGRSCEDI 442
Query: 2404 DECKVIHDVCRNGECVNDRGSYHCICKTGYT-PDITGTSCVDLNECN--QAPKPCNFICK 2460
+EC C EC N GSY C C+ GY D+ G +C D++EC C++ C
Sbjct: 443 NECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCI 499
Query: 2461 NTEGSYQCSCPK-GYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTC---KCPPG 2514
N GS+QCSCP GY L +GR+C+D+DEC T HNC C N GGF C +CP
Sbjct: 500 NIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 559
Query: 2515 F 2515
+
Sbjct: 560 Y 560
Score = 194 bits (492), Expect = 1e-48
Identities = 151/487 (31%), Positives = 213/487 (43%), Gaps = 79/487 (16%)
Query: 1717 KMCCCSYNIGRAWNKPCEQCPIPST------DEFATLCGSQRPGFVIDI----YTGLPVD 1766
K CC +GRA + C F C + +D+ T ++
Sbjct: 107 KRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIE 166
Query: 1767 IDECREIPGV---CENG-----VCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-V 1817
++E +E P + C G C + C C VG+ + CED++EC G
Sbjct: 167 VEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 1818 CQRNAECINTAGSYRCD----CKPGYRFTSTGQCNDRNECQE-IPNICSHGQCIDTVGSF 1872
C+ CINT GS+RC C GY T C D +EC+ I N C +T+GSF
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSF 286
Query: 1873 YCL----CHTGFKTNDDQTMCLDINECERDA--CGNG-TCRNTIGSFNCR-----CNHGF 1920
C C +GF D C+DINEC + C G TC NT GS+ C+ C G+
Sbjct: 287 RCRPKLQCKSGF-IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 1921 ILSHNND-CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLL 1979
L+ C+DVDECA + +C+N+ GSF+C+C GY R CVD+NEC
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 1980 EPRKCAPGTCQNLDGSYRCICPPGY--SLQNEKCEDIDECVEEPEICALGTCSNTEGSFK 2037
P + C+N GSY C C G+ S+ CEDI+EC P C+ C+N GS++
Sbjct: 406 YPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQ 462
Query: 2038 CLCPEGFSLSS-SGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPC 2096
C C G+ LS G C+D+ +C+ P + H C + G
Sbjct: 463 CYCRRGYQLSDVDGVTCEDI-----------DECALP-TGGHICSYRCINIPG------- 503
Query: 2097 ELCPTEPDEAFRQICPYGSGIIVGPDD-SAVDMDECKE--PDVCKHGQCINTDGSYRC-- 2151
+F+ CP SG + P+ + D+DEC + + C N G +RC
Sbjct: 504 ---------SFQCSCP-SSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLA 553
Query: 2152 -ECPFGY 2157
ECP Y
Sbjct: 554 FECPENY 560
Score = 176 bits (445), Expect = 4e-43
Identities = 151/471 (32%), Positives = 210/471 (44%), Gaps = 89/471 (18%)
Query: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRG-----ECIDVDECEKNP-----CA 500
+Y +V Y C G+ +C + + LD+ G + I+V+E +++P C
Sbjct: 127 EYSLMVGYQC--GQVFR---ACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCR 181
Query: 501 GG-----ECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGR-CINTDGSFH 554
GG +C + C C GYQ C D++EC+ C G CINT GSF
Sbjct: 182 GGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 555 C----VCNAGFHVTRDGKNCEDMDEC--SIRNMCLNGMCINEDGSFKC----ICKPGFQL 604
C C G+ +T D +C+D+DEC I N + +C N GSF+C CK GF
Sbjct: 242 CQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 605 ASDGRYCKDINEC-ETPGICMNGR-CVNTDGSYRCE-----CFPGLAVGLDGRVCVDTH- 656
+ G C DINEC C G C+NT+GSY C+ C G + +G CVD
Sbjct: 301 DALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDE 359
Query: 657 ---MRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFG--------EPCQPCPAQ--- 702
C G++ C+ + C C + Y G CQ P +
Sbjct: 360 CAPPAEPCGKGHR---CV----NSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 703 -----NSAEYQALCSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSGY 754
Y CS G ++ G DINEC+ P C C N+ G+Y+C C GY
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CSQE-CANVYGSYQCYCRRGY 469
Query: 755 EV-DSTGKNCVDINECVL--NSLLCDNGQCRNTPGSFVCTCP-KGFIYKPDLKTCEDIDE 810
++ D G C DI+EC L +C + +C N PGSF C+CP G+ P+ + C+DIDE
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDE 528
Query: 811 CES---SPCINGVCKNSPGSFIC---EC-----SSESTLDPTKTICIETIK 850
C + + IN C N G F C EC S +TL KT + IK
Sbjct: 529 CVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIK 579
Score = 166 bits (421), Expect = 2e-40
Identities = 135/430 (31%), Positives = 188/430 (43%), Gaps = 73/430 (16%)
Query: 532 DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC--SIRNMCLNGMCIN 589
D C + G C +C +T C C G+ + DG +CED++EC + L CIN
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 590 EDGSFKC----ICKPGFQLASDGRYCKDINECETPGI--CM-NGRCVNTDGSYRCECFPG 642
GSF+C C G++L D CKDI+ECE+ GI C+ + C NT GS+RC
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNS-CKDIDECES-GIHNCLPDFICQNTLGSFRCR---- 289
Query: 643 LAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQ 702
+ C G+ + L + +EC S G C
Sbjct: 290 --------------PKLQCKSGFIQDA----LGNCIDINECLSISAPCPIGHTCINTEGS 331
Query: 703 NSAEYQAL-CSSGPGMTSAGS---DINECALDPDICPNGI-CENLRGTYKCICNSGYEVD 757
+ + C G + G+ D++ECA + C G C N G+++C C +GY D
Sbjct: 332 YTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 758 STGKNCVDINECV-LNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPC 816
+ CVD+NEC LC + +C NT GS++C+C GF D ++CEDI+EC SSPC
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC 450
Query: 817 INGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQT---VIDGRCEININGATLKS 873
+ C N GS+ C C L + E I T + RC INI G + +
Sbjct: 451 -SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRC-INIPG-SFQC 507
Query: 874 QCCSSLGAAWGSPCTLCQVDPICGKGYSRI-KGTQCEDIDECEVFPGVCK-NGLCVNTRG 931
C SS GY G C+DIDEC C N C N +G
Sbjct: 508 SCPSS--------------------GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 932 SFKC---QCP 938
F+C +CP
Sbjct: 548 GFRCLAFECP 557
Score = 166 bits (419), Expect = 4e-40
Identities = 136/437 (31%), Positives = 178/437 (40%), Gaps = 110/437 (25%)
Query: 780 QCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLD 839
QCR+T VC+C G+ D +CED++EC + GS C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECIT------------GSHSCR-------- 228
Query: 840 PTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKG 899
L C +++G+ CQ D CG G
Sbjct: 229 -------------------------------LGESCINTVGSF------RCQRDSSCGTG 251
Query: 900 YSRIKGTQCEDIDECEVFPGVC-KNGLCVNTRGSFKC----QCPSGMTLDATGRICLDIR 954
Y + C+DIDECE C + +C NT GSF+C QC SG DA G C+DI
Sbjct: 252 YELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDIN 310
Query: 955 L-----------ETCFLRYEDEEC--TLPIAGR----HRMDACCCSVGAAWGTEECEECP 997
TC C +P GR + C V +EC P
Sbjct: 311 ECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV------DEC--AP 362
Query: 998 MRNTPEYEELCPRGPGFATKEITNGKPF------FKDINECKMIPS-LCTHGKCRNTIGS 1050
C PG E G F D+NEC+ P LC H KC NT+GS
Sbjct: 363 PAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGS 421
Query: 1051 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKN 1110
+ C C GF L + R+C DI+EC SP C + +C N G ++C C GY+ +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVT 478
Query: 1111 CMDIDECQRDPLLCRGG-----VCHNTEGSYRCECP-PGHQLSPNISACIDINECELSAH 1164
C DIDEC L GG C N GS++C CP G++L+PN C DI+EC H
Sbjct: 479 CEDIDEC----ALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIH 534
Query: 1165 LCP-NGRCVNLIGKYQC 1180
C N C N+ G ++C
Sbjct: 535 NCSINETCFNIQGGFRC 551
Score = 156 bits (394), Expect = 3e-37
Identities = 146/482 (30%), Positives = 191/482 (39%), Gaps = 100/482 (20%)
Query: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSENLNLCGNGQ-CL 1421
D C G C Q C++T C C GY DG +C D++EC + C G+ C+
Sbjct: 178 DRCRGGGP-CKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 1422 NAPGGYRCE----CDMGFVPSADGKACEDIDECS--LPNICVFGTCHNLPGLFRC----E 1471
N G +RC+ C G+ + D +C+DIDEC + N C N G FRC +
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 1472 CEIGYELDRSGGNCTDVNECLDPTT-CISGN-CVNTPGSYIC-----DCPPDFELNPTRV 1524
C+ G+ D G NC D+NECL + C G+ C+NT GSY C +C + LN
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 1525 GCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSE 1584
CVD C P G C N G C C G + MC
Sbjct: 353 RCVDV--DECAPPAEPCGKGH--RCVNSPG----SFRCECKTGYYFDGISRMCV------ 398
Query: 1585 YKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTR 1644
D++ECQ PG G KC NT GS+ C C G+ L+ D R
Sbjct: 399 ---------------------DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGR 437
Query: 1645 VCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQ 1704
C+D+NEC + C C N G+Y C C RR Y+ D
Sbjct: 438 SCEDINECSS-SPCSQ-ECANVYGSYQCYC----------------RRG--YQLSDVDGV 477
Query: 1705 TCDGELLFNMTKKMCCCSYNIGRAWNKPCE-QCPIPSTDEFATLCGSQRPGFVIDIYTGL 1763
TC+ + CSY R N P QC PS+ G+ +
Sbjct: 478 TCEDIDECALPTGGHICSY---RCINIPGSFQCSCPSS------------GYRLAPNGRN 522
Query: 1764 PVDIDEC-REIPGVCENGVCINMVGSFRC---ECPVGFFYNDKLLVCEDIDECQNGPVCQ 1819
DIDEC I N C N+ G FRC ECP + + L E D + C+
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCR 582
Query: 1820 RN 1821
N
Sbjct: 583 PN 584
Score = 136 bits (343), Expect = 3e-31
Identities = 124/427 (29%), Positives = 176/427 (41%), Gaps = 94/427 (22%)
Query: 1470 CECEIGYELDRSGGNCTDVNECLDPT-TCISG-NCVNTPGSYICD----CPPDFELNPTR 1523
C C +GY+L G +C DVNEC+ + +C G +C+NT GS+ C C +EL
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYEL---- 254
Query: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS 1583
T +C DI C + I + C +LG P C +
Sbjct: 255 -----TEDNSCK-DI--------DECESGIHNCLPDFICQNTLGSFRCRPKLQCKS---- 296
Query: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCR-----CPTGY 1637
GF + + + DI+EC + C G CINT GS+ C+ C GY
Sbjct: 297 ----------GFIQDALGNCI-DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 1638 YLNEDTRVCDDVNECETPGI-CGPG-TCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLC 1695
+LNE+ C DV+EC P CG G C N+ G++ C C Y C+D+
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 1696 YRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGF 1755
Y + C + + +C CS GF
Sbjct: 406 Y-----PGRLCGHKCENTLGSYLCSCSV------------------------------GF 430
Query: 1756 VIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYND-KLLVCEDIDEC-- 1812
+ + DI+EC P E C N+ GS++C C G+ +D + CEDIDEC
Sbjct: 431 RLSVDGRSCEDINECSSSPCSQE---CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECAL 487
Query: 1813 -QNGPVCQRNAECINTAGSYRCDC-KPGYRFTSTGQ-CNDRNECQEIPNICSHGQ-CIDT 1868
G +C + CIN GS++C C GYR G+ C D +EC + CS + C +
Sbjct: 488 PTGGHIC--SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNI 545
Query: 1869 VGSFYCL 1875
G F CL
Sbjct: 546 QGGFRCL 552
Score = 103 bits (258), Expect = 2e-21
Identities = 85/302 (28%), Positives = 112/302 (37%), Gaps = 64/302 (21%)
Query: 118 HCNIRCMNGGSCSDDH--------CLCQKGYI----GTHC--------GQPVCESG--CL 155
+ N RC GG C C C GY G C G C G C+
Sbjct: 175 YLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 156 N---GGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQM----CQGQLSGIVCTKTL 208
N RC + C Y T +D C + I N + CQ L C L
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDI--DECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 209 CCAT--VGRAWGH------------PCEM------------CPAQPHPCRRGFIPNIRTG 242
C + + A G+ PC + C C RG+ N
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 243 ACQDVDECQAIPGLC-QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG 301
C DVDEC C +G C+N+ GSF C+C G+ + +S+ C D++EC PG G
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 302 GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCD 361
+C NT+ SY C C GF S DG C D+ ++ CS + QC C
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCEDI------NECSSSPCSQECANVYGSYQCYCR 466
Query: 362 AG 363
G
Sbjct: 467 RG 468
Score = 89.4 bits (220), Expect = 5e-17
Identities = 86/284 (30%), Positives = 125/284 (44%), Gaps = 51/284 (17%)
Query: 84 ICRHSCGDGFCSRPNMCTCPSGQIAPSCGSR-SIQHC---NIRCMNGGSC--SDDHCLCQ 137
IC+++ G C RP + C SG I + G+ I C + C G +C ++ CQ
Sbjct: 278 ICQNTLGSFRC-RPKL-QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQ 335
Query: 138 KGYIGTHCGQPVCESG--CLNGGRCVAP-------NRCACTYGFTGPQCERDYRTGPCFT 188
K G + E G C++ C P +RC + G +C +TG F
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC----KTGYYFD 391
Query: 189 VISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCE------MCPAQPHPCRRGFIPNIRTG 242
IS +MC C GR GH CE +C C GF ++
Sbjct: 392 GIS-RMC--------VDVNECQRYPGRLCGHKCENTLGSYLCS-----CSVGFRLSVDGR 437
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEV-SQKCEDIDECSTIPG--IC 299
+C+D++EC + P C C N GS++C C G++L++V CEDIDEC+ G IC
Sbjct: 438 SCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC 494
Query: 300 EGGECTNTVSSYFCKCP-PGFYTSPDGTRCIDVRPGYCYTALTN 342
C N S+ C CP G+ +P+G C D+ C T + N
Sbjct: 495 -SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI--DECVTGIHN 535
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 245 bits (625), Expect = 5e-64
Identities = 140/396 (35%), Positives = 188/396 (47%), Gaps = 14/396 (3%)
Query: 1129 CHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHS 1188
C N GSY C C G+ L+ + + C + C + H C CVN+ G + C C GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 1189 TPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNI 1248
D CV +D C+ N GCE C N++GSY C C GFAL PD+++CT ID C + +
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 1249 CDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCD 1308
C +C N Y C C GF + D KTC +N C LN C C N + S+ C C
Sbjct: 372 CQ-HECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC-EHECVNMEESYYCRCH 429
Query: 1309 MGYS-GKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW-IGDGIK-CTDLD 1365
GY+ GKT C+ ++ C H C +C NT SF C CS G+ I + +K C+ +D
Sbjct: 430 RGYTLDPNGKT-CSRVDHCAQQDHGC--EQLCLNTEDSFVCQCSEGFLINEDLKTCSRVD 486
Query: 1366 ECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSENLNLCGNGQCLNA 1423
C H C C N S+ C C EG+ DG TC LD C+ + C + C+++
Sbjct: 487 YCLLSDHGCEY--SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSS 543
Query: 1424 PGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGG 1483
+ C+C G++ DGK C D C + C N + CEC G+ L G
Sbjct: 544 EDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGK 603
Query: 1484 NCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFEL 1519
C + C CVN SYIC C F L
Sbjct: 604 RCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVL 639
Score = 240 bits (612), Expect = 2e-62
Identities = 137/441 (31%), Positives = 204/441 (46%), Gaps = 44/441 (9%)
Query: 2217 CAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCIC 2276
CA C+N GSY C+C GY+L D+ C+ +D C H+C + C N+ G+++C C
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL---CVNVPGSFVCQC 305
Query: 2277 GPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNRE 2336
GY DG+ CV + C ++ CE+ C+N GSY C+C++GF +P++ C +
Sbjct: 306 YSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC--TKI 362
Query: 2337 GYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGF 2396
YC + + CQ N + C C G P KK C
Sbjct: 363 DYCASS--NHGCQHECVNTDD--SYSCHCLKGFTLNPD------------KKTCRR---- 402
Query: 2397 MTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN 2456
I+ C + C + ECVN SY+C C GYT D G +C ++ C Q C
Sbjct: 403 ------INYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCE 455
Query: 2457 FICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFT 2516
+C NTE S+ C C +G+++ ED ++C +D C H C++ CVN F C+CP G
Sbjct: 456 QLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEG-- 513
Query: 2517 QHHTSCIDNNECTSDINLC-----GSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDEC 2571
H D C + ++ C G + C ++ SF C+C G+ L + G +C D C
Sbjct: 514 --HVLRSDGKTC-AKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVC 570
Query: 2572 EG-NHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYK 2630
+ +H C+H C N Y C C +G+ +C ++ C S H C N SY
Sbjct: 571 QAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYI 630
Query: 2631 CMCPAGFQYEQFSGGCQDINE 2651
C C GF + C+ E
Sbjct: 631 CKCSEGFVLAEDGRRCKKCTE 651
Score = 214 bits (546), Expect = 8e-55
Identities = 143/445 (32%), Positives = 200/445 (44%), Gaps = 53/445 (11%)
Query: 1824 CINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKT 1882
CIN GSY C CK GY S C ++ C + C C++ GSF C C++G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 1883 NDDQTMCLDINECERDACG-NGTCRNTIGSFNCRCNHGFILSHNND-CIDVDECASGNGN 1940
+D C+ ++ C + G C N GS+ C+C+ GF L+ + C +D CAS N
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 1941 LCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCIC 2000
C++ +C+NT S+ C C +G+ + PD +TC IN C L C C N++ SY C C
Sbjct: 372 -CQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRC 428
Query: 2001 PPGYSLQ--NEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRM 2058
GY+L + C +D C ++ C C NTE SF C C EGF ++ + C R+
Sbjct: 429 HRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCS--RV 485
Query: 2059 SYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGII 2118
YC G CE D +F CP G ++
Sbjct: 486 DYCLLSDHG----------------------------CEYSCVNMDRSFACQCPEGH-VL 516
Query: 2119 VGPDDSAVDMDECKEPDV-CKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNP 2175
+ +D C D C+H C++++ S+ C+C GYIL G C D C +
Sbjct: 517 RSDGKTCAKLDSCALGDHGCEHS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDH 575
Query: 2176 CGNGTCKNVIGGFECTCEEGF---EPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKC 2232
C N + C C EGF E G +D+ C C CVN SY CKC
Sbjct: 576 GCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDV--CKSTHHGCEHICVNNGNSYICKC 633
Query: 2233 PVGYVLREDRRMCKDEDECEEGKHD 2257
G+VL ED R CK +C EG D
Sbjct: 634 SEGFVLAEDGRRCK---KCTEGPID 655
Score = 213 bits (543), Expect = 2e-54
Identities = 140/453 (30%), Positives = 203/453 (44%), Gaps = 64/453 (14%)
Query: 1853 CQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCL--DINECERDACGNGTCRNTIG 1910
C + + C+H CI+ GS+ C C G+ N DQT C D+ E C C N G
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPG 299
Query: 1911 SFNCRCNHGFILSHNND-CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGR 1969
SF C+C G+ L+ + C+ VD CAS N C + +C+N GS+ CQC+EG+ + PD +
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHG-CEH-ECVNADGSYLCQCHEGFALNPDKK 357
Query: 1970 TCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK--CEDIDECVEEPEICALG 2027
TC I+ C C C N D SY C C G++L +K C I+ C C
Sbjct: 358 TCTKIDYCASSNHGC-QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCE-H 415
Query: 2028 TCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCAL 2087
C N E S+ C C G++L +G+ C R+ +C + G
Sbjct: 416 ECVNMEESYYCRCHRGYTLDPNGKTCS--RVDHCAQQDHG-------------------- 453
Query: 2088 KGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVC---KHG---Q 2141
CE +++F +C G ++ D+ C D C HG
Sbjct: 454 --------CEQLCLNTEDSF--VCQCSEGFLINE-----DLKTCSRVDYCLLSDHGCEYS 498
Query: 2142 CINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGF--- 2196
C+N D S+ C+CP G++L G C D C++G+ +C + F C C EG+
Sbjct: 499 CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILR 558
Query: 2197 EPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKH 2256
E G TC + C C CVN+ SY C+C G+ L ED + C+ +D C+ H
Sbjct: 559 EDG--KTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHH 616
Query: 2257 DCTEKQMECKNLIGTYMCICGPGYQRRPDGEGC 2289
C + C N +Y+C C G+ DG C
Sbjct: 617 GC---EHICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 202 bits (515), Expect = 3e-51
Identities = 138/488 (28%), Positives = 203/488 (41%), Gaps = 62/488 (12%)
Query: 2251 CEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNT 2310
C +H+C C N+ G+Y+C C GY D C ++ C + CE C+N
Sbjct: 242 CSTLEHNCAHF---CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNV 297
Query: 2311 RGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRG 2370
GS+ C+C G+ + + C+ YC +E + C+ N + C C G
Sbjct: 298 PGSFVCQCYSGYALAEDGKRCV--AVDYCASE--NHGCEHECVNADG--SYLCQCHEGFA 351
Query: 2371 WGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICK 2430
P KK C ID C + C++ ECVN SY C C
Sbjct: 352 LNPD------------KKTC----------TKIDYCASSNHGCQH-ECVNTDDSYSCHCL 388
Query: 2431 TGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECA 2490
G+T + +C +N C C C N E SY C C +GY L +G++C +D CA
Sbjct: 389 KGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCA 448
Query: 2491 TKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLC-----GSKGICQNTP 2545
+ H C+ LC+NT F C+C GF + D C S ++ C G + C N
Sbjct: 449 QQDHGCEQLCLNTEDSFVCQCSEGFLINE----DLKTC-SRVDYCLLSDHGCEYSCVNMD 503
Query: 2546 GSFTCECQRGFSLDQTGSSCEDVDECE-GNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQ 2604
SF C+C G L G +C +D C G+H C+H C + + C C +GY+
Sbjct: 504 RSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKT 563
Query: 2605 CVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCS 2664
C ++ C + C N+ SY C C GF+ + C+ + C S C + C
Sbjct: 564 CRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICV 623
Query: 2665 NTEGGYLCGCPPGYFRIGQGH----CVSG-----------MGMGRGNPEPP---VSGEMD 2706
N Y+C C G+ G C G +G N E V+G +D
Sbjct: 624 NNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIID 683
Query: 2707 DNSLSPEA 2714
++SP+A
Sbjct: 684 SLTISPKA 691
Score = 199 bits (506), Expect = 3e-50
Identities = 130/455 (28%), Positives = 188/455 (41%), Gaps = 49/455 (10%)
Query: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE 1260
CS + C FC N GSY C C+ G+ L DQ +C D C + C+ C N+PG
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCE-QLCVNVPGS 300
Query: 1261 YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC 1320
+ C CY G+ +ED K CV V+ C + C C N GS++C C G++ K C
Sbjct: 301 FVCQCYSGYALAEDGKRCVAVDYCASENHGC-EHECVNADGSYLCQCHEGFALNPDKKTC 359
Query: 1321 TDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHA 1378
T I+ C H C C NT S+ C C G+ D C ++ C+ C
Sbjct: 360 TKIDYCASSNHGCQHE--CVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-- 415
Query: 1379 DCKNTMGSYRCLCKEGYTGD--GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFV 1436
+C N SY C C GYT D G TC+ +D C++ + C CLN + C+C GF+
Sbjct: 416 ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLNTEDSFVCQCSEGFL 474
Query: 1437 PSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT 1496
+ D K C +D C L + +C N+ F C+C G+ L G C ++ C
Sbjct: 475 INEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDH 534
Query: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
+CV++ S++C C + L ++G T ++
Sbjct: 535 GCEHSCVSSEDSFVCQCFEGYILR----------------------EDGKTCRRKDVCQA 572
Query: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL 1616
+ CE + Y C EGFR D C+
Sbjct: 573 IDHG-------------CEHICVNSDDSYTCECL--EGFRLAEDGKRCRRKDVCKSTHHG 617
Query: 1617 CQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE 1651
C+ C+N S+ C+C G+ L ED R C E
Sbjct: 618 CE-HICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 192 bits (489), Expect = 3e-48
Identities = 122/393 (31%), Positives = 177/393 (45%), Gaps = 48/393 (12%)
Query: 1947 CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL 2006
CIN GS+ C+C +GY + D TC + C +E C C N+ GS+ C C GY+L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 2007 QNE--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK 2064
+ +C +D C E C C N +GS+ C C EGF+L+ + C ++ YC
Sbjct: 312 AEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDKKTCT--KIDYC--- 365
Query: 2065 FEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDS 2124
S NH Q C D+++ C G + PD
Sbjct: 366 ---------ASSNHGCQHEC----------------VNTDDSYS--CHCLKGFTLNPDKK 398
Query: 2125 A---VDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNG 2179
++ +P C+H +C+N + SY C C GY L G C D C+ +
Sbjct: 399 TCRRINYCALNKPG-CEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ 456
Query: 2180 TCKNVIGGFECTCEEGFEPGP-MMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVL 2238
C N F C C EGF + TC ++ C + C + CVN S+ C+CP G+VL
Sbjct: 457 LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVL 516
Query: 2239 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTK 2298
R D + C D C G H C + C + +++C C GY R DG+ C ++ CQ
Sbjct: 517 RSDGKTCAKLDSCALGDHGC---EHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAI 573
Query: 2299 PGICENGRCLNTRGSYTCECNDGFTASPNQDEC 2331
CE+ C+N+ SYTCEC +GF + + C
Sbjct: 574 DHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRC 605
Score = 184 bits (468), Expect = 8e-46
Identities = 132/476 (27%), Positives = 194/476 (40%), Gaps = 66/476 (13%)
Query: 821 CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLG 880
C N PGS++C C L+ +T C I+ C + D CE Q C ++
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTC--RIQDLC--AMEDHNCE----------QLCVNVP 298
Query: 881 AAWGSPCTLCQVDPICGKGYSRIK-GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPS 939
++ +CQ C GY+ + G +C +D C C++ CVN GS+ CQC
Sbjct: 299 GSF-----VCQ----CYSGYALAEDGKRCVAVDYCASENHGCEHE-CVNADGSYLCQCHE 348
Query: 940 GMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMR 999
G L+ + C I D C S C+ +
Sbjct: 349 GFALNPDKKTCTKI------------------------DYCASS------NHGCQHECVN 378
Query: 1000 NTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGF 1059
Y C +G + K + IN C + C H +C N S+ CRC G+
Sbjct: 379 TDDSYSCHCLKG-----FTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGY 432
Query: 1060 ALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQR 1119
LD + C+ +D C C + C+NT F C+C EG+ +K C +D C
Sbjct: 433 TLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLIN-EDLKTCSRVDYCLL 490
Query: 1120 DPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQ 1179
C C N + S+ C+CP GH L + C ++ C L H C + CV+ +
Sbjct: 491 SDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS-CVSSEDSFV 548
Query: 1180 CACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDI 1239
C C GY D C D C ++ GCE C NS+ SY C C GF L D + C
Sbjct: 549 CQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRK 608
Query: 1240 DECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGT 1295
D C+ + C+ C N Y C C +GF+ +ED + C E ++ + G+
Sbjct: 609 DVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGS 663
Score = 184 bits (466), Expect = 1e-45
Identities = 128/464 (27%), Positives = 190/464 (40%), Gaps = 54/464 (11%)
Query: 1296 CENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI 1355
C N GS++C C GY +T C + C + HNC + +C N GSF C C G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNVPGSFVCQCYSGYA 310
Query: 1356 --GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSEN 1411
DG +C +D C++ H C +C N GSY C C EG+ D TCT +D C+ +
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEH--ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASS 368
Query: 1412 LNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCE 1471
+ C + +C+N Y C C GF + D K C I+ C+L C N+ + C
Sbjct: 369 NHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCR 427
Query: 1472 CEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRS 1531
C GY LD +G C+ V+ C C+NT S++C C F +N C +R
Sbjct: 428 CHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTC--SRV 485
Query: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPG 1591
C L D+G CE + CP
Sbjct: 486 DYCLL-----SDHG----------------------------CEYSCVNMDRSFACQCPE 512
Query: 1592 GEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE 1651
G R + T +D C C+ C+++ SF C+C GY L ED + C +
Sbjct: 513 GHVLRSDGKT--CAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569
Query: 1652 CETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELL 1711
C+ C N+ +YTC C + G C R+ +C ++ C+ +
Sbjct: 570 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRC--RRKDVCKSTHHG----CEHICV 623
Query: 1712 FNMTKKMCCCSYNIGRAWN-KPCEQCPIPSTDEFATLCGSQRPG 1754
N +C CS A + + C++C D + GS+ G
Sbjct: 624 NNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLG 667
Score = 182 bits (462), Expect = 4e-45
Identities = 135/435 (31%), Positives = 190/435 (43%), Gaps = 66/435 (15%)
Query: 1777 CENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQN-GPVCQRNAECINTAGSYRCDC 1835
CE +C+N+ GSF C+C G+ + C +D C + C+ EC+N GSY C C
Sbjct: 290 CEQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH--ECVNADGSYLCQC 346
Query: 1836 KPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINE 1894
G+ + C + C + C H +C++T S+ C C GF N D+ C IN
Sbjct: 347 HEGFALNPDKKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINY 405
Query: 1895 CERDACG-NGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDECASGNGNLCRNGQCINTVG 1952
C + G C N S+ CRC+ G+ L N C VD CA + C C+NT
Sbjct: 406 CALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHG-CEQ-LCLNTED 463
Query: 1953 SFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--K 2010
SF CQC+EG+ + D +TC ++ CLL C +C N+D S+ C CP G+ L+++
Sbjct: 464 SFVCQCSEGFLINEDLKTCSRVDYCLLSDHGC-EYSCVNMDRSFACQCPEGHVLRSDGKT 522
Query: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC 2070
C +D C C +C ++E SF C C EG+ L G+ C+ R C A G
Sbjct: 523 CAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILREDGKTCR--RKDVCQAIDHG--- 576
Query: 2071 SSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 2130
CE D+++ C G + A D
Sbjct: 577 -------------------------CEHICVNSDDSYTCECLEGFRL-------AEDGKR 604
Query: 2131 CKEPDVCK---HG---QCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCK 2182
C+ DVCK HG C+N SY C+C G++LA G C E G
Sbjct: 605 CRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE-------GPIDLV 657
Query: 2183 NVIGGFECTCEEGFE 2197
VI G + EE FE
Sbjct: 658 FVIDGSKSLGEENFE 672
Score = 176 bits (445), Expect = 4e-43
Identities = 116/384 (30%), Positives = 167/384 (43%), Gaps = 37/384 (9%)
Query: 453 CQLVRYLCQNGRCIPTPGSCRCECNKGFQLDL-RGECIDVDEC--EKNPCAGGECINNQG 509
C + + C + CI PGS C C +G+ L+ + C D C E + C C+N G
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCE-QLCVNVPG 299
Query: 510 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569
S+ CQC +GY C +D C C + C+N DGS+ C C+ GF + D K
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKT 358
Query: 570 CEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCV 629
C +D C+ N C+N D S+ C C GF L D + C+ IN C CV
Sbjct: 359 CTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECV 418
Query: 630 NTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTE 689
N + SY C C G + +G+ C + C + G E C +TE
Sbjct: 419 NMEESYYCRCHRGYTLDPNGKTC------------SRVDHCAQQDHGC----EQLCLNTE 462
Query: 690 YAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCI 749
+F CQ E CS ++ C L C C N+ ++ C
Sbjct: 463 DSF--VCQCSEGFLINEDLKTCSR----------VDYCLLSDHGCEYS-CVNMDRSFACQ 509
Query: 750 CNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID 809
C G+ + S GK C ++ C L C++ C ++ SFVC C +G+I + D KTC D
Sbjct: 510 CPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKD 568
Query: 810 ECES-SPCINGVCKNSPGSFICEC 832
C++ +C NS S+ CEC
Sbjct: 569 VCQAIDHGCEHICVNSDDSYTCEC 592
Score = 172 bits (436), Expect = 4e-42
Identities = 114/406 (28%), Positives = 177/406 (43%), Gaps = 35/406 (8%)
Query: 449 VTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDEC-EKNPCAGGECIN 506
+ D C + + C+ C+ PGS C+C G+ L G+ C+ VD C +N EC+N
Sbjct: 279 IQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVN 337
Query: 507 NQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRD 566
GSY CQC G+ + C ID C + C + C+NTD S+ C C GF + D
Sbjct: 338 ADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPD 396
Query: 567 GKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNG 626
K C ++ C++ C+N + S+ C C G+ L +G+ C ++ C
Sbjct: 397 KKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ 456
Query: 627 RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCA 686
C+NT+ S+ C+C G + D + C + C+ G E C
Sbjct: 457 LCLNTEDSFVCQCSEGFLINEDLKTC------------SRVDYCLLSDHGC----EYSCV 500
Query: 687 STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTY 746
+ + +F CQ CP E L S G + ++ CAL C + C + ++
Sbjct: 501 NMDRSFA--CQ-CP-----EGHVLRSDG----KTCAKLDSCALGDHGCEHS-CVSSEDSF 547
Query: 747 KCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806
C C GY + GK C + C C++ C N+ S+ C C +GF D K C
Sbjct: 548 VCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCR 606
Query: 807 DIDECESS-PCINGVCKNSPGSFICECSSESTLDPTKTICIETIKG 851
D C+S+ +C N+ S+IC+CS L C + +G
Sbjct: 607 RKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEG 652
Score = 157 bits (398), Expect = 1e-37
Identities = 117/442 (26%), Positives = 170/442 (38%), Gaps = 65/442 (14%)
Query: 1420 CLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELD 1479
C+N PG Y C C G++ ++D C D C++ + C N+PG F C+C GY L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 1480 RSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVD-----TRSGNC 1534
G C V+ C CVN GSY+C C F LNP + C + + C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGC 372
Query: 1535 YLDIRPRGDNGDTACSNEIGVGVSKASC----CCSLGKAWGTPCEMCPAVNTSE-YKILC 1589
+ D+ C + K +C C+L K CE VN E Y C
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNK---PGCEH-ECVNMEESYYCRC 428
Query: 1590 PGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDV 1649
G PN T +D C + C+ C+NT SF C+C G+ +NED + C V
Sbjct: 429 HRGYTLDPNGKT--CSRVDHCAQQDHGCE-QLCLNTEDSFVCQCSEGFLINEDLKTCSRV 485
Query: 1650 NECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGE 1709
+ C +C N ++ C CP ++ + G C
Sbjct: 486 DYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTC---------------------- 523
Query: 1710 LLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDE 1769
K+ C+ + CE + S D F C G+++ D
Sbjct: 524 ------AKLDSCALG-----DHGCEHSCVSSEDSFVCQCFE---GYILREDGKTCRRKDV 569
Query: 1770 CREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAE-----C 1824
C+ I CE+ +C+N S+ CEC GF + ED C+ VC+ C
Sbjct: 570 CQAIDHGCEH-ICVNSDDSYTCECLEGF------RLAEDGKRCRRKDVCKSTHHGCEHIC 622
Query: 1825 INTAGSYRCDCKPGYRFTSTGQ 1846
+N SY C C G+ G+
Sbjct: 623 VNNGNSYICKCSEGFVLAEDGR 644
Score = 78.6 bits (192), Expect = 8e-14
Identities = 52/171 (30%), Positives = 76/171 (44%), Gaps = 11/171 (6%)
Query: 203 VCTKTLC----CATVGRAWGHPCEMCPAQ-PHPCRRGFIPNIRTGACQDVDECQAIPGLC 257
V K LC C+T+ H C P C++G+I N C+ D C C
Sbjct: 231 VFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC 290
Query: 258 QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPP 317
+ C+N GSF C+C +G+ L E ++C +D C++ CE EC N SY C+C
Sbjct: 291 EQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHE 348
Query: 318 GFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSP 368
GF +PD C + Y A +N C ++ + C C G +P
Sbjct: 349 GFALNPDKKTCTKID----YCASSNHGCQHECVNTDDSYSCHCLKGFTLNP 395
Score = 77.0 bits (188), Expect = 2e-13
Identities = 77/279 (27%), Positives = 101/279 (36%), Gaps = 58/279 (20%)
Query: 89 CGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD--------HCLCQKGY 140
C GF P+ TC R I +C +N C + +C C +GY
Sbjct: 387 CLKGFTLNPDKKTC-----------RRINYC---ALNKPGCEHECVNMEESYYCRCHRGY 432
Query: 141 I----------GTHCGQPV--CESGCLNGGRCVAPNRCACTYGFTGPQ----CER-DYRT 183
HC Q CE CLN C C+ GF + C R DY
Sbjct: 433 TLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFV---CQCSEGFLINEDLKTCSRVDYCL 489
Query: 184 -------GPCFTVISNQMCQG------QLSGIVCTKTLCCATVGRAWGHPCEMCPAQ-PH 229
C + + CQ + G C K CA H C
Sbjct: 490 LSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 549
Query: 230 PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDI 289
C G+I C+ D CQAI C+ C+N+ S+ C+C G +L E ++C
Sbjct: 550 QCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRK 608
Query: 290 DECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 328
D C + CE C N +SY CKC GF + DG RC
Sbjct: 609 DVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 73.6 bits (179), Expect = 3e-12
Identities = 72/304 (23%), Positives = 104/304 (34%), Gaps = 67/304 (22%)
Query: 57 NVCGSRYNAYCCPGWKTLPGGNQCIVPI--------CRHSC-----------GDGFCSRP 97
NV GS + C G+ G +C+ C H C +GF P
Sbjct: 296 NVPGS-FVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNP 354
Query: 98 NMCTCPSGQIAPSCGSRSIQHC-------NIRCMNGGSCSDDHCLCQK-GYIGTHCGQPV 149
+ TC S C + C+ G + + D C++ Y + +P
Sbjct: 355 DKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN--KPG 412
Query: 150 CESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLC 209
CE C+N C +C R Y P +G C++
Sbjct: 413 CEHECVN-----MEESYYC-------RCHRGYTLDP--------------NGKTCSRVDH 446
Query: 210 CATVGRAWGHPCEMCPAQPHP-----CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCIN 264
CA H CE C GF+ N C VD C C+ +C+N
Sbjct: 447 CAQQD----HGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEY-SCVN 501
Query: 265 TVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPD 324
SF C+CP GH L + C +D C+ CE C ++ S+ C+C G+ D
Sbjct: 502 MDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILRED 560
Query: 325 GTRC 328
G C
Sbjct: 561 GKTC 564
Score = 39.7 bits (91), Expect = 0.043
Identities = 64/281 (22%), Positives = 97/281 (34%), Gaps = 64/281 (22%)
Query: 63 YNAYCCPGW------KTLPGGNQCIV--PICRHSCGD-----------GFCSRPNMCTCP 103
Y+ +C G+ KT N C + P C H C + G+ PN TC
Sbjct: 383 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCS 442
Query: 104 SGQIAPSCGSRSIQHCNIRCMNGGSCSDDH--CLCQKGYIGT----------HC--GQPV 149
C + C C+N ++D C C +G++ +C
Sbjct: 443 R---VDHCAQQD-HGCEQLCLN----TEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHG 494
Query: 150 CESGCLNGGRCVAPNRCACTYGFT----GPQCER-------DYRTG-PCFTVISNQMCQ- 196
CE C+N R A C C G G C + D+ C + + +CQ
Sbjct: 495 CEYSCVNMDRSFA---CQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQC 551
Query: 197 --GQL---SGIVCTKTLCCATVGRAWGHPC-EMCPAQPHPCRRGFIPNIRTGACQDVDEC 250
G + G C + C + H C + C GF C+ D C
Sbjct: 552 FEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVC 611
Query: 251 QAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDE 291
++ C+ C+N S+ CKC G L E ++C+ E
Sbjct: 612 KSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 245 bits (625), Expect = 5e-64
Identities = 140/396 (35%), Positives = 188/396 (47%), Gaps = 14/396 (3%)
Query: 1129 CHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHS 1188
C N GSY C C G+ L+ + + C + C + H C CVN+ G + C C GY
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 1189 TPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNI 1248
D CV +D C+ N GCE C N++GSY C C GFAL PD+++CT ID C + +
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 1249 CDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCD 1308
C +C N Y C C GF + D KTC +N C LN C C N + S+ C C
Sbjct: 372 CQ-HECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGC-EHECVNMEESYYCRCH 429
Query: 1309 MGYS-GKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW-IGDGIK-CTDLD 1365
GY+ GKT C+ ++ C H C +C NT SF C CS G+ I + +K C+ +D
Sbjct: 430 RGYTLDPNGKT-CSRVDHCAQQDHGC--EQLCLNTEDSFVCQCSEGFLINEDLKTCSRVD 486
Query: 1366 ECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSENLNLCGNGQCLNA 1423
C H C C N S+ C C EG+ DG TC LD C+ + C + C+++
Sbjct: 487 YCLLSDHGCEY--SCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSS 543
Query: 1424 PGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGG 1483
+ C+C G++ DGK C D C + C N + CEC G+ L G
Sbjct: 544 EDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGK 603
Query: 1484 NCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFEL 1519
C + C CVN SYIC C F L
Sbjct: 604 RCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVL 639
Score = 240 bits (612), Expect = 2e-62
Identities = 137/441 (31%), Positives = 204/441 (46%), Gaps = 44/441 (9%)
Query: 2217 CAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCIC 2276
CA C+N GSY C+C GY+L D+ C+ +D C H+C + C N+ G+++C C
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL---CVNVPGSFVCQC 305
Query: 2277 GPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNRE 2336
GY DG+ CV + C ++ CE+ C+N GSY C+C++GF +P++ C +
Sbjct: 306 YSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKTC--TKI 362
Query: 2337 GYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGF 2396
YC + + CQ N + C C G P KK C
Sbjct: 363 DYCASS--NHGCQHECVNTDD--SYSCHCLKGFTLNPD------------KKTCRR---- 402
Query: 2397 MTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN 2456
I+ C + C + ECVN SY+C C GYT D G +C ++ C Q C
Sbjct: 403 ------INYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCE 455
Query: 2457 FICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFT 2516
+C NTE S+ C C +G+++ ED ++C +D C H C++ CVN F C+CP G
Sbjct: 456 QLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEG-- 513
Query: 2517 QHHTSCIDNNECTSDINLC-----GSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDEC 2571
H D C + ++ C G + C ++ SF C+C G+ L + G +C D C
Sbjct: 514 --HVLRSDGKTC-AKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVC 570
Query: 2572 EG-NHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYK 2630
+ +H C+H C N Y C C +G+ +C ++ C S H C N SY
Sbjct: 571 QAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYI 630
Query: 2631 CMCPAGFQYEQFSGGCQDINE 2651
C C GF + C+ E
Sbjct: 631 CKCSEGFVLAEDGRRCKKCTE 651
Score = 214 bits (546), Expect = 8e-55
Identities = 143/445 (32%), Positives = 200/445 (44%), Gaps = 53/445 (11%)
Query: 1824 CINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKT 1882
CIN GSY C CK GY S C ++ C + C C++ GSF C C++G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 1883 NDDQTMCLDINECERDACG-NGTCRNTIGSFNCRCNHGFILSHNND-CIDVDECASGNGN 1940
+D C+ ++ C + G C N GS+ C+C+ GF L+ + C +D CAS N
Sbjct: 312 AEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHG 371
Query: 1941 LCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCIC 2000
C++ +C+NT S+ C C +G+ + PD +TC IN C L C C N++ SY C C
Sbjct: 372 -CQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRC 428
Query: 2001 PPGYSLQ--NEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRM 2058
GY+L + C +D C ++ C C NTE SF C C EGF ++ + C R+
Sbjct: 429 HRGYTLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLINEDLKTCS--RV 485
Query: 2059 SYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGII 2118
YC G CE D +F CP G ++
Sbjct: 486 DYCLLSDHG----------------------------CEYSCVNMDRSFACQCPEGH-VL 516
Query: 2119 VGPDDSAVDMDECKEPDV-CKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNP 2175
+ +D C D C+H C++++ S+ C+C GYIL G C D C +
Sbjct: 517 RSDGKTCAKLDSCALGDHGCEHS-CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDH 575
Query: 2176 CGNGTCKNVIGGFECTCEEGF---EPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKC 2232
C N + C C EGF E G +D+ C C CVN SY CKC
Sbjct: 576 GCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDV--CKSTHHGCEHICVNNGNSYICKC 633
Query: 2233 PVGYVLREDRRMCKDEDECEEGKHD 2257
G+VL ED R CK +C EG D
Sbjct: 634 SEGFVLAEDGRRCK---KCTEGPID 655
Score = 213 bits (543), Expect = 2e-54
Identities = 140/453 (30%), Positives = 203/453 (44%), Gaps = 64/453 (14%)
Query: 1853 CQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCL--DINECERDACGNGTCRNTIG 1910
C + + C+H CI+ GS+ C C G+ N DQT C D+ E C C N G
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPG 299
Query: 1911 SFNCRCNHGFILSHNND-CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGR 1969
SF C+C G+ L+ + C+ VD CAS N C + +C+N GS+ CQC+EG+ + PD +
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHG-CEH-ECVNADGSYLCQCHEGFALNPDKK 357
Query: 1970 TCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK--CEDIDECVEEPEICALG 2027
TC I+ C C C N D SY C C G++L +K C I+ C C
Sbjct: 358 TCTKIDYCASSNHGC-QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCE-H 415
Query: 2028 TCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCAL 2087
C N E S+ C C G++L +G+ C R+ +C + G
Sbjct: 416 ECVNMEESYYCRCHRGYTLDPNGKTCS--RVDHCAQQDHG-------------------- 453
Query: 2088 KGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVC---KHG---Q 2141
CE +++F +C G ++ D+ C D C HG
Sbjct: 454 --------CEQLCLNTEDSF--VCQCSEGFLINE-----DLKTCSRVDYCLLSDHGCEYS 498
Query: 2142 CINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGF--- 2196
C+N D S+ C+CP G++L G C D C++G+ +C + F C C EG+
Sbjct: 499 CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILR 558
Query: 2197 EPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKH 2256
E G TC + C C CVN+ SY C+C G+ L ED + C+ +D C+ H
Sbjct: 559 EDG--KTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHH 616
Query: 2257 DCTEKQMECKNLIGTYMCICGPGYQRRPDGEGC 2289
C + C N +Y+C C G+ DG C
Sbjct: 617 GC---EHICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 202 bits (515), Expect = 3e-51
Identities = 138/488 (28%), Positives = 203/488 (41%), Gaps = 62/488 (12%)
Query: 2251 CEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNT 2310
C +H+C C N+ G+Y+C C GY D C ++ C + CE C+N
Sbjct: 242 CSTLEHNCAHF---CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNV 297
Query: 2311 RGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRG 2370
GS+ C+C G+ + + C+ YC +E + C+ N + C C G
Sbjct: 298 PGSFVCQCYSGYALAEDGKRCV--AVDYCASE--NHGCEHECVNADG--SYLCQCHEGFA 351
Query: 2371 WGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICK 2430
P KK C ID C + C++ ECVN SY C C
Sbjct: 352 LNPD------------KKTC----------TKIDYCASSNHGCQH-ECVNTDDSYSCHCL 388
Query: 2431 TGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECA 2490
G+T + +C +N C C C N E SY C C +GY L +G++C +D CA
Sbjct: 389 KGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCA 448
Query: 2491 TKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLC-----GSKGICQNTP 2545
+ H C+ LC+NT F C+C GF + D C S ++ C G + C N
Sbjct: 449 QQDHGCEQLCLNTEDSFVCQCSEGFLINE----DLKTC-SRVDYCLLSDHGCEYSCVNMD 503
Query: 2546 GSFTCECQRGFSLDQTGSSCEDVDECE-GNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQ 2604
SF C+C G L G +C +D C G+H C+H C + + C C +GY+
Sbjct: 504 RSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKT 563
Query: 2605 CVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCS 2664
C ++ C + C N+ SY C C GF+ + C+ + C S C + C
Sbjct: 564 CRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICV 623
Query: 2665 NTEGGYLCGCPPGYFRIGQGH----CVSG-----------MGMGRGNPEPP---VSGEMD 2706
N Y+C C G+ G C G +G N E V+G +D
Sbjct: 624 NNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIID 683
Query: 2707 DNSLSPEA 2714
++SP+A
Sbjct: 684 SLTISPKA 691
Score = 199 bits (506), Expect = 3e-50
Identities = 130/455 (28%), Positives = 188/455 (41%), Gaps = 49/455 (10%)
Query: 1201 CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE 1260
CS + C FC N GSY C C+ G+ L DQ +C D C + C+ C N+PG
Sbjct: 242 CSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCE-QLCVNVPGS 300
Query: 1261 YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC 1320
+ C CY G+ +ED K CV V+ C + C C N GS++C C G++ K C
Sbjct: 301 FVCQCYSGYALAEDGKRCVAVDYCASENHGC-EHECVNADGSYLCQCHEGFALNPDKKTC 359
Query: 1321 TDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHA 1378
T I+ C H C C NT S+ C C G+ D C ++ C+ C
Sbjct: 360 TKIDYCASSNHGCQHE--CVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEH-- 415
Query: 1379 DCKNTMGSYRCLCKEGYTGD--GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFV 1436
+C N SY C C GYT D G TC+ +D C++ + C CLN + C+C GF+
Sbjct: 416 ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGC-EQLCLNTEDSFVCQCSEGFL 474
Query: 1437 PSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT 1496
+ D K C +D C L + +C N+ F C+C G+ L G C ++ C
Sbjct: 475 INEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDH 534
Query: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
+CV++ S++C C + L ++G T ++
Sbjct: 535 GCEHSCVSSEDSFVCQCFEGYILR----------------------EDGKTCRRKDVCQA 572
Query: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL 1616
+ CE + Y C EGFR D C+
Sbjct: 573 IDHG-------------CEHICVNSDDSYTCECL--EGFRLAEDGKRCRRKDVCKSTHHG 617
Query: 1617 CQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE 1651
C+ C+N S+ C+C G+ L ED R C E
Sbjct: 618 CE-HICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
Score = 192 bits (489), Expect = 3e-48
Identities = 122/393 (31%), Positives = 177/393 (45%), Gaps = 48/393 (12%)
Query: 1947 CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL 2006
CIN GS+ C+C +GY + D TC + C +E C C N+ GS+ C C GY+L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYAL 311
Query: 2007 QNE--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK 2064
+ +C +D C E C C N +GS+ C C EGF+L+ + C ++ YC
Sbjct: 312 AEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHEGFALNPDKKTCT--KIDYC--- 365
Query: 2065 FEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDS 2124
S NH Q C D+++ C G + PD
Sbjct: 366 ---------ASSNHGCQHEC----------------VNTDDSYS--CHCLKGFTLNPDKK 398
Query: 2125 A---VDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNG 2179
++ +P C+H +C+N + SY C C GY L G C D C+ +
Sbjct: 399 TCRRINYCALNKPG-CEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ 456
Query: 2180 TCKNVIGGFECTCEEGFEPGP-MMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVL 2238
C N F C C EGF + TC ++ C + C + CVN S+ C+CP G+VL
Sbjct: 457 LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVL 516
Query: 2239 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTK 2298
R D + C D C G H C + C + +++C C GY R DG+ C ++ CQ
Sbjct: 517 RSDGKTCAKLDSCALGDHGC---EHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAI 573
Query: 2299 PGICENGRCLNTRGSYTCECNDGFTASPNQDEC 2331
CE+ C+N+ SYTCEC +GF + + C
Sbjct: 574 DHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRC 605
Score = 184 bits (468), Expect = 8e-46
Identities = 132/476 (27%), Positives = 194/476 (40%), Gaps = 66/476 (13%)
Query: 821 CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLG 880
C N PGS++C C L+ +T C I+ C + D CE Q C ++
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTC--RIQDLC--AMEDHNCE----------QLCVNVP 298
Query: 881 AAWGSPCTLCQVDPICGKGYSRIK-GTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPS 939
++ +CQ C GY+ + G +C +D C C++ CVN GS+ CQC
Sbjct: 299 GSF-----VCQ----CYSGYALAEDGKRCVAVDYCASENHGCEHE-CVNADGSYLCQCHE 348
Query: 940 GMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMR 999
G L+ + C I D C S C+ +
Sbjct: 349 GFALNPDKKTCTKI------------------------DYCASS------NHGCQHECVN 378
Query: 1000 NTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGF 1059
Y C +G + K + IN C + C H +C N S+ CRC G+
Sbjct: 379 TDDSYSCHCLKG-----FTLNPDKKTCRRINYCALNKPGCEH-ECVNMEESYYCRCHRGY 432
Query: 1060 ALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQR 1119
LD + C+ +D C C + C+NT F C+C EG+ +K C +D C
Sbjct: 433 TLDPNGKTCSRVDHCAQQDHGCEQ-LCLNTEDSFVCQCSEGFLIN-EDLKTCSRVDYCLL 490
Query: 1120 DPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQ 1179
C C N + S+ C+CP GH L + C ++ C L H C + CV+ +
Sbjct: 491 SDHGCEYS-CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHS-CVSSEDSFV 548
Query: 1180 CACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDI 1239
C C GY D C D C ++ GCE C NS+ SY C C GF L D + C
Sbjct: 549 CQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRK 608
Query: 1240 DECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGT 1295
D C+ + C+ C N Y C C +GF+ +ED + C E ++ + G+
Sbjct: 609 DVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGS 663
Score = 184 bits (466), Expect = 1e-45
Identities = 128/464 (27%), Positives = 190/464 (40%), Gaps = 54/464 (11%)
Query: 1296 CENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI 1355
C N GS++C C GY +T C + C + HNC + +C N GSF C C G+
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNVPGSFVCQCYSGYA 310
Query: 1356 --GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSEN 1411
DG +C +D C++ H C +C N GSY C C EG+ D TCT +D C+ +
Sbjct: 311 LAEDGKRCVAVDYCASENHGCEH--ECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASS 368
Query: 1412 LNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCE 1471
+ C + +C+N Y C C GF + D K C I+ C+L C N+ + C
Sbjct: 369 NHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCR 427
Query: 1472 CEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRS 1531
C GY LD +G C+ V+ C C+NT S++C C F +N C +R
Sbjct: 428 CHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTC--SRV 485
Query: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPG 1591
C L D+G CE + CP
Sbjct: 486 DYCLL-----SDHG----------------------------CEYSCVNMDRSFACQCPE 512
Query: 1592 GEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE 1651
G R + T +D C C+ C+++ SF C+C GY L ED + C +
Sbjct: 513 GHVLRSDGKT--CAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILREDGKTCRRKDV 569
Query: 1652 CETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELL 1711
C+ C N+ +YTC C + G C R+ +C ++ C+ +
Sbjct: 570 CQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRC--RRKDVCKSTHHG----CEHICV 623
Query: 1712 FNMTKKMCCCSYNIGRAWN-KPCEQCPIPSTDEFATLCGSQRPG 1754
N +C CS A + + C++C D + GS+ G
Sbjct: 624 NNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLG 667
Score = 182 bits (462), Expect = 4e-45
Identities = 135/435 (31%), Positives = 190/435 (43%), Gaps = 66/435 (15%)
Query: 1777 CENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQN-GPVCQRNAECINTAGSYRCDC 1835
CE +C+N+ GSF C+C G+ + C +D C + C+ EC+N GSY C C
Sbjct: 290 CEQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH--ECVNADGSYLCQC 346
Query: 1836 KPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINE 1894
G+ + C + C + C H +C++T S+ C C GF N D+ C IN
Sbjct: 347 HEGFALNPDKKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPDKKTCRRINY 405
Query: 1895 CERDACG-NGTCRNTIGSFNCRCNHGFILSHN-NDCIDVDECASGNGNLCRNGQCINTVG 1952
C + G C N S+ CRC+ G+ L N C VD CA + C C+NT
Sbjct: 406 CALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHG-CEQ-LCLNTED 463
Query: 1953 SFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--K 2010
SF CQC+EG+ + D +TC ++ CLL C +C N+D S+ C CP G+ L+++
Sbjct: 464 SFVCQCSEGFLINEDLKTCSRVDYCLLSDHGC-EYSCVNMDRSFACQCPEGHVLRSDGKT 522
Query: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC 2070
C +D C C +C ++E SF C C EG+ L G+ C+ R C A G
Sbjct: 523 CAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILREDGKTCR--RKDVCQAIDHG--- 576
Query: 2071 SSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 2130
CE D+++ C G + A D
Sbjct: 577 -------------------------CEHICVNSDDSYTCECLEGFRL-------AEDGKR 604
Query: 2131 CKEPDVCK---HG---QCINTDGSYRCECPFGYILA--GNECVDTDECSVGNPCGNGTCK 2182
C+ DVCK HG C+N SY C+C G++LA G C E G
Sbjct: 605 CRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTE-------GPIDLV 657
Query: 2183 NVIGGFECTCEEGFE 2197
VI G + EE FE
Sbjct: 658 FVIDGSKSLGEENFE 672
Score = 176 bits (445), Expect = 4e-43
Identities = 116/384 (30%), Positives = 167/384 (43%), Gaps = 37/384 (9%)
Query: 453 CQLVRYLCQNGRCIPTPGSCRCECNKGFQLDL-RGECIDVDEC--EKNPCAGGECINNQG 509
C + + C + CI PGS C C +G+ L+ + C D C E + C C+N G
Sbjct: 242 CSTLEHNCAHF-CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCE-QLCVNVPG 299
Query: 510 SYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKN 569
S+ CQC +GY C +D C C + C+N DGS+ C C+ GF + D K
Sbjct: 300 SFVCQCYSGYALAEDGKRCVAVDYCASENHGCEH-ECVNADGSYLCQCHEGFALNPDKKT 358
Query: 570 CEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCV 629
C +D C+ N C+N D S+ C C GF L D + C+ IN C CV
Sbjct: 359 CTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECV 418
Query: 630 NTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTE 689
N + SY C C G + +G+ C + C + G E C +TE
Sbjct: 419 NMEESYYCRCHRGYTLDPNGKTC------------SRVDHCAQQDHGC----EQLCLNTE 462
Query: 690 YAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCI 749
+F CQ E CS ++ C L C C N+ ++ C
Sbjct: 463 DSF--VCQCSEGFLINEDLKTCSR----------VDYCLLSDHGCEYS-CVNMDRSFACQ 509
Query: 750 CNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID 809
C G+ + S GK C ++ C L C++ C ++ SFVC C +G+I + D KTC D
Sbjct: 510 CPEGHVLRSDGKTCAKLDSCALGDHGCEH-SCVSSEDSFVCQCFEGYILREDGKTCRRKD 568
Query: 810 ECES-SPCINGVCKNSPGSFICEC 832
C++ +C NS S+ CEC
Sbjct: 569 VCQAIDHGCEHICVNSDDSYTCEC 592
Score = 172 bits (436), Expect = 4e-42
Identities = 114/406 (28%), Positives = 177/406 (43%), Gaps = 35/406 (8%)
Query: 449 VTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDEC-EKNPCAGGECIN 506
+ D C + + C+ C+ PGS C+C G+ L G+ C+ VD C +N EC+N
Sbjct: 279 IQDLCAMEDHNCEQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVN 337
Query: 507 NQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRD 566
GSY CQC G+ + C ID C + C + C+NTD S+ C C GF + D
Sbjct: 338 ADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQH-ECVNTDDSYSCHCLKGFTLNPD 396
Query: 567 GKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNG 626
K C ++ C++ C+N + S+ C C G+ L +G+ C ++ C
Sbjct: 397 KKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ 456
Query: 627 RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCA 686
C+NT+ S+ C+C G + D + C + C+ G E C
Sbjct: 457 LCLNTEDSFVCQCSEGFLINEDLKTC------------SRVDYCLLSDHGC----EYSCV 500
Query: 687 STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTY 746
+ + +F CQ CP E L S G + ++ CAL C + C + ++
Sbjct: 501 NMDRSFA--CQ-CP-----EGHVLRSDG----KTCAKLDSCALGDHGCEHS-CVSSEDSF 547
Query: 747 KCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806
C C GY + GK C + C C++ C N+ S+ C C +GF D K C
Sbjct: 548 VCQCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCR 606
Query: 807 DIDECESS-PCINGVCKNSPGSFICECSSESTLDPTKTICIETIKG 851
D C+S+ +C N+ S+IC+CS L C + +G
Sbjct: 607 RKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEG 652
Score = 157 bits (398), Expect = 1e-37
Identities = 117/442 (26%), Positives = 170/442 (38%), Gaps = 65/442 (14%)
Query: 1420 CLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELD 1479
C+N PG Y C C G++ ++D C D C++ + C N+PG F C+C GY L
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALA 312
Query: 1480 RSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVD-----TRSGNC 1534
G C V+ C CVN GSY+C C F LNP + C + + C
Sbjct: 313 EDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGC 372
Query: 1535 YLDIRPRGDNGDTACSNEIGVGVSKASC----CCSLGKAWGTPCEMCPAVNTSE-YKILC 1589
+ D+ C + K +C C+L K CE VN E Y C
Sbjct: 373 QHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNK---PGCEH-ECVNMEESYYCRC 428
Query: 1590 PGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDV 1649
G PN T +D C + C+ C+NT SF C+C G+ +NED + C V
Sbjct: 429 HRGYTLDPNGKT--CSRVDHCAQQDHGCE-QLCLNTEDSFVCQCSEGFLINEDLKTCSRV 485
Query: 1650 NECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGE 1709
+ C +C N ++ C CP ++ + G C
Sbjct: 486 DYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTC---------------------- 523
Query: 1710 LLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDE 1769
K+ C+ + CE + S D F C G+++ D
Sbjct: 524 ------AKLDSCALG-----DHGCEHSCVSSEDSFVCQCFE---GYILREDGKTCRRKDV 569
Query: 1770 CREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAE-----C 1824
C+ I CE+ +C+N S+ CEC GF + ED C+ VC+ C
Sbjct: 570 CQAIDHGCEH-ICVNSDDSYTCECLEGF------RLAEDGKRCRRKDVCKSTHHGCEHIC 622
Query: 1825 INTAGSYRCDCKPGYRFTSTGQ 1846
+N SY C C G+ G+
Sbjct: 623 VNNGNSYICKCSEGFVLAEDGR 644
Score = 78.6 bits (192), Expect = 8e-14
Identities = 52/171 (30%), Positives = 76/171 (44%), Gaps = 11/171 (6%)
Query: 203 VCTKTLC----CATVGRAWGHPCEMCPAQ-PHPCRRGFIPNIRTGACQDVDECQAIPGLC 257
V K LC C+T+ H C P C++G+I N C+ D C C
Sbjct: 231 VFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNC 290
Query: 258 QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPP 317
+ C+N GSF C+C +G+ L E ++C +D C++ CE EC N SY C+C
Sbjct: 291 EQ-LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCE-HECVNADGSYLCQCHE 348
Query: 318 GFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSP 368
GF +PD C + Y A +N C ++ + C C G +P
Sbjct: 349 GFALNPDKKTCTKID----YCASSNHGCQHECVNTDDSYSCHCLKGFTLNP 395
Score = 77.0 bits (188), Expect = 2e-13
Identities = 77/279 (27%), Positives = 101/279 (36%), Gaps = 58/279 (20%)
Query: 89 CGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD--------HCLCQKGY 140
C GF P+ TC R I +C +N C + +C C +GY
Sbjct: 387 CLKGFTLNPDKKTC-----------RRINYC---ALNKPGCEHECVNMEESYYCRCHRGY 432
Query: 141 I----------GTHCGQPV--CESGCLNGGRCVAPNRCACTYGFTGPQ----CER-DYRT 183
HC Q CE CLN C C+ GF + C R DY
Sbjct: 433 TLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFV---CQCSEGFLINEDLKTCSRVDYCL 489
Query: 184 -------GPCFTVISNQMCQG------QLSGIVCTKTLCCATVGRAWGHPCEMCPAQ-PH 229
C + + CQ + G C K CA H C
Sbjct: 490 LSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVC 549
Query: 230 PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDI 289
C G+I C+ D CQAI C+ C+N+ S+ C+C G +L E ++C
Sbjct: 550 QCFEGYILREDGKTCRRKDVCQAIDHGCEH-ICVNSDDSYTCECLEGFRLAEDGKRCRRK 608
Query: 290 DECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 328
D C + CE C N +SY CKC GF + DG RC
Sbjct: 609 DVCKSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRC 646
Score = 73.6 bits (179), Expect = 3e-12
Identities = 72/304 (23%), Positives = 104/304 (34%), Gaps = 67/304 (22%)
Query: 57 NVCGSRYNAYCCPGWKTLPGGNQCIVPI--------CRHSC-----------GDGFCSRP 97
NV GS + C G+ G +C+ C H C +GF P
Sbjct: 296 NVPGS-FVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNP 354
Query: 98 NMCTCPSGQIAPSCGSRSIQHC-------NIRCMNGGSCSDDHCLCQK-GYIGTHCGQPV 149
+ TC S C + C+ G + + D C++ Y + +P
Sbjct: 355 DKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN--KPG 412
Query: 150 CESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLC 209
CE C+N C +C R Y P +G C++
Sbjct: 413 CEHECVN-----MEESYYC-------RCHRGYTLDP--------------NGKTCSRVDH 446
Query: 210 CATVGRAWGHPCEMCPAQPHP-----CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCIN 264
CA H CE C GF+ N C VD C C+ +C+N
Sbjct: 447 CAQQD----HGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEY-SCVN 501
Query: 265 TVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPD 324
SF C+CP GH L + C +D C+ CE C ++ S+ C+C G+ D
Sbjct: 502 MDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCE-HSCVSSEDSFVCQCFEGYILRED 560
Query: 325 GTRC 328
G C
Sbjct: 561 GKTC 564
Score = 39.7 bits (91), Expect = 0.043
Identities = 64/281 (22%), Positives = 97/281 (34%), Gaps = 64/281 (22%)
Query: 63 YNAYCCPGW------KTLPGGNQCIV--PICRHSCGD-----------GFCSRPNMCTCP 103
Y+ +C G+ KT N C + P C H C + G+ PN TC
Sbjct: 383 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCS 442
Query: 104 SGQIAPSCGSRSIQHCNIRCMNGGSCSDDH--CLCQKGYIGT----------HC--GQPV 149
C + C C+N ++D C C +G++ +C
Sbjct: 443 R---VDHCAQQD-HGCEQLCLN----TEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHG 494
Query: 150 CESGCLNGGRCVAPNRCACTYGFT----GPQCER-------DYRTG-PCFTVISNQMCQ- 196
CE C+N R A C C G G C + D+ C + + +CQ
Sbjct: 495 CEYSCVNMDRSFA---CQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQC 551
Query: 197 --GQL---SGIVCTKTLCCATVGRAWGHPC-EMCPAQPHPCRRGFIPNIRTGACQDVDEC 250
G + G C + C + H C + C GF C+ D C
Sbjct: 552 FEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVC 611
Query: 251 QAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDE 291
++ C+ C+N S+ CKC G L E ++C+ E
Sbjct: 612 KSTHHGCEH-ICVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 244 bits (624), Expect = 7e-64
Identities = 176/545 (32%), Positives = 245/545 (44%), Gaps = 91/545 (16%)
Query: 1005 EELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSE 1064
E C G AT + P+ + EC+M+ C H + + C +G +L +E
Sbjct: 34 EACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLE------ELHCATGISLANE 87
Query: 1065 ERNC------------TDIDECRISPDLCGRGQCVNTPG-DFECKCDEGYESGFMMMKNC 1111
+ C T + C C G+ G E GY+ G + C
Sbjct: 88 QDRCATPHGDNASLEATFVKRC---CHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACC 144
Query: 1112 --------------------MDIDECQRDPLL---CRGG-----VCHNTEGSYRCECPPG 1143
++++E Q DP L CRGG C +T C C G
Sbjct: 145 VKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVG 204
Query: 1144 HQLSPNISACIDINECELSAHLCPNGR-CVNLIGKYQC----ACNPGYHSTPDRLFCVDI 1198
+QL + +C D+NEC +H C G C+N +G ++C +C GY T D C DI
Sbjct: 205 YQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDI 263
Query: 1199 DECSIMNGGC--ETFCTNSEGSYEC----SCQPGFALMPDQRSCTDIDECEDNPNICD-G 1251
DEC C + C N+ GS+ C C+ GF + +C DI+EC C G
Sbjct: 264 DECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF-IQDALGNCIDINECLSISAPCPIG 322
Query: 1252 GQCTNIPGEYRCL-----CYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFIC 1305
C N G Y C C G+ +E+ CVDV+EC C G C N+ GSF C
Sbjct: 323 HTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRC 382
Query: 1306 HCDMGYSGKKGKTGCTDINECE-IGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCT 1362
C GY C D+NEC+ CG C NT GS+ CSCS G+ DG C
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCE 440
Query: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY---TGDGFTCTDLDECS--ENLNLCGN 1417
D++ECS+ CSQ +C N GSY+C C+ GY DG TC D+DEC+ ++C +
Sbjct: 441 DINECSSSP--CSQ--ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-S 495
Query: 1418 GQCLNAPGGYRCEC-DMGFVPSADGKACEDIDEC--SLPNICVFGTCHNLPGLFRC---E 1471
+C+N PG ++C C G+ + +G+ C+DIDEC + N + TC N+ G FRC E
Sbjct: 496 YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFE 555
Query: 1472 CEIGY 1476
C Y
Sbjct: 556 CPENY 560
Score = 225 bits (574), Expect = 4e-58
Identities = 140/386 (36%), Positives = 194/386 (50%), Gaps = 41/386 (10%)
Query: 1085 QCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCE---- 1139
QC +T + C C GY+ +C D++EC CR G C NT GS+RC+
Sbjct: 189 QCRDTGDEVVCSCFVGYQL-LSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSS 247
Query: 1140 CPPGHQLSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCA----CNPGYHSTPDRLF 1194
C G++L+ + ++C DI+ECE H C P+ C N +G ++C C G+ D L
Sbjct: 248 CGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF--IQDALG 304
Query: 1195 -CVDIDECSIMNGGCET--FCTNSEGSYEC-----SCQPGFALMPDQRSCTDIDECEDNP 1246
C+DI+EC ++ C C N+EGSY C +C G+ L + C D+DEC
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 1247 NICDGG-QCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFIC 1305
C G +C N PG +RC C G+ + CVDVNEC P CENT GS++C
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLC 424
Query: 1306 HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW---IGDGIKCT 1362
C +G+ C DINEC + C + C N GS++C C G+ DG+ C
Sbjct: 425 SCSVGFRLSVDGRSCEDINEC--SSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 1363 DLDECS--NGTHMCSQHADCKNTMGSYRCLC-KEGY--TGDGFTCTDLDECSENLNLCG- 1416
D+DEC+ G H+CS C N GS++C C GY +G C D+DEC ++ C
Sbjct: 481 DIDECALPTGGHICSYR--CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 1417 NGQCLNAPGGYRC---ECDMGFVPSA 1439
N C N GG+RC EC + SA
Sbjct: 539 NETCFNIQGGFRCLAFECPENYRRSA 564
Score = 218 bits (555), Expect = 7e-56
Identities = 180/611 (29%), Positives = 246/611 (40%), Gaps = 116/611 (18%)
Query: 1121 PLLCRGGVCHNTEGS-----YRCECPPGHQLSPNISAC-----IDINECELSAHLCPNGR 1170
PLL GG+ G C GH+++ + C + EC + C
Sbjct: 13 PLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQC---- 68
Query: 1171 CVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALM 1230
C + + + CA + DR D S+ + C C C G A
Sbjct: 69 CHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCC-------HC-CLLGRAAQ 120
Query: 1231 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASE-------DMKTCVDVNE 1283
+SC ++ G QC + +R C + + ++V E
Sbjct: 121 AQGQSC--------EYSLMVGYQCGQV---FRACCVKSQETGDLDVGGLQETDKIIEVEE 169
Query: 1284 CDLNPNI---CLSG-----TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK 1335
+P + C G C +T +C C +GY C D+NEC G+H+C
Sbjct: 170 EQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRL 229
Query: 1336 HAVCTNTAGSFKC----SCSPGW-IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL 1390
C NT GSF+C SC G+ + + C D+DEC +G H C C+NT+GS+RC
Sbjct: 230 GESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCR 289
Query: 1391 ----CKEGYTGDGF-TCTDLDECSENLNLCGNGQ-CLNAPGGYRCE-----CDMGFVPSA 1439
CK G+ D C D++EC C G C+N G Y C+ C G+ +
Sbjct: 290 PKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNE 349
Query: 1440 DGKACEDIDECSLP-NICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTT 1496
+G C D+DEC+ P C G C N PG FRCEC+ GY D C DVNEC P
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
C NT GSY+C C F L+ C D + + CS E
Sbjct: 410 LCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN------------ECSSSPCSQECANV 457
Query: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPG- 1615
C C G Y++ G V EDIDEC G
Sbjct: 458 YGSYQCYCRRG-----------------YQLSDVDG---------VTCEDIDECALPTGG 491
Query: 1616 -LCQGGKCINTFGSFQCRCP-TGYYLNEDTRVCDDVNECETPGI--CGPG-TCYNTVGNY 1670
+C +CIN GSFQC CP +GY L + R C D++EC T GI C TC+N G +
Sbjct: 492 HICSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVT-GIHNCSINETCFNIQGGF 549
Query: 1671 TCI---CPPDY 1678
C+ CP +Y
Sbjct: 550 RCLAFECPENY 560
Score = 213 bits (542), Expect = 2e-54
Identities = 156/479 (32%), Positives = 220/479 (45%), Gaps = 71/479 (14%)
Query: 1109 KNCMDIDE----CQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAH 1164
K C + E Q + L C G+ E RC P G +A ++ + H
Sbjct: 59 KECRMVQEQCCHSQLEELHCATGISLANEQD-RCATPHGD------NASLEATFVKRCCH 111
Query: 1165 LCPNGRCVNLIGK---------YQC-----AC----------NPGYHSTPDRLFCVDID- 1199
C GR G+ YQC AC + G D++ V+ +
Sbjct: 112 CCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ 171
Query: 1200 ECSIMN------GGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQ 1253
E +N G C+ C ++ CSC G+ L+ D SC D++EC + C G+
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGE 231
Query: 1254 -CTNIPGEYRCL----CYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFICH- 1306
C N G +RC C G+ +ED +C D++EC+ + CL C+NT GSF C
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRP 290
Query: 1307 ---CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-----SCSPGWI--G 1356
C G+ + C DINEC + C C NT GS+ C +C G+
Sbjct: 291 KLQCKSGFI-QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNE 349
Query: 1357 DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFT--CTDLDECSENLN- 1413
+G +C D+DEC+ C + C N+ GS+RC CK GY DG + C D++EC
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECE 1473
LCG+ +C N G Y C C +GF S DG++CEDI+ECS + C N+ G ++C C
Sbjct: 410 LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCR 466
Query: 1474 IGYEL-DRSGGNCTDVNECLDPT--TCISGNCVNTPGSYICDCPPD-FELNPTRVGCVD 1528
GY+L D G C D++EC PT S C+N PGS+ C CP + L P C D
Sbjct: 467 RGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQD 525
Score = 208 bits (530), Expect = 5e-53
Identities = 145/408 (35%), Positives = 189/408 (46%), Gaps = 56/408 (13%)
Query: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
G C+ +C +T C C G+ + C D E C T + C++G S N V
Sbjct: 184 GPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNE--CITG--SHSCRLGESCINTVG 238
Query: 2360 KSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKV-IHDVCRNGEC 2418
C D G G + C DIDEC+ IH+ + C
Sbjct: 239 SFRCQRDSSCGTGYE---------LTEDNSCK----------DIDECESGIHNCLPDFIC 279
Query: 2419 VNDRGSYHCI----CKTGYTPDITGTSCVDLNECNQ--APKPCNFICKNTEGSYQC---- 2468
N GS+ C CK+G+ D G +C+D+NEC AP P C NTEGSY C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 2469 -SCPKGYILQEDGRSCKDLDECATKQHNCQ--FLCVNTIGGFTCKCPPGFTQHHTS--CI 2523
+C +GY L E+G C D+DECA C CVN+ G F C+C G+ S C+
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 2524 DNNECTS-DINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQ 2582
D NEC LCG K C+NT GS+ C C GF L G SCED++EC + C C
Sbjct: 399 DVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQECA 455
Query: 2583 NIIGGYRCSCPQGY-LQHYQWNQCVDENECL---SAHICGGASCHNTLGSYKCMCPA-GF 2637
N+ G Y+C C +GY L C D +EC HIC C N GS++C CP+ G+
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCSCPSSGY 514
Query: 2638 QYEQFSGGCQDINECGSAQAPCSYG--CSNTEGGYLC---GCPPGYFR 2680
+ CQDI+EC + CS C N +GG+ C CP Y R
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRR 562
Score = 207 bits (526), Expect = 2e-52
Identities = 135/415 (32%), Positives = 186/415 (44%), Gaps = 58/415 (13%)
Query: 2168 DECSVGNPCGNGTCKNVIGGFECTCEEGFEP-GPMMTCEDINECAQNPLLCAF--RCVNT 2224
D C G PC C++ C+C G++ ++CED+NEC C C+NT
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2225 YGSYECK----CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI----C 2276
GS+ C+ C GY L ED CKD DECE G H+C + C+N +G++ C C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFI-CQNTLGSFRCRPKLQC 294
Query: 2277 GPGYQRRPDGEGCVDENECQTKPGICENGR-CLNTRGSYTCE-----CNDGFTASPNQDE 2330
G+ + G C+D NEC + C G C+NT GSYTC+ C G+ +
Sbjct: 295 KSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 2331 CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLC 2390
C+D E C C G N C C G + +C
Sbjct: 354 CVDVDE--CAPPA--EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC------------ 397
Query: 2391 PHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQ 2450
D++EC+ +C N GSY C C G+ + G SC D+NEC+
Sbjct: 398 ----------VDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 2451 APKPCNFICKNTEGSYQCSCPKGYILQE-DGRSCKDLDECA--TKQHNCQFLCVNTIGGF 2507
+P C+ C N GSYQC C +GY L + DG +C+D+DECA T H C + C+N G F
Sbjct: 448 SP--CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSF 505
Query: 2508 TCKCPPG---FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC---ECQRGF 2556
C CP + +C D +EC + I+ C C N G F C EC +
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 198 bits (503), Expect = 7e-50
Identities = 126/379 (33%), Positives = 176/379 (46%), Gaps = 48/379 (12%)
Query: 2349 QIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA---DIDE 2405
++ +P C RG GP + C G C G +++G D++E
Sbjct: 166 EVEEEQEDPYLNDRC-----RGGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNE 219
Query: 2406 CKVIHDVCRNGE-CVNDRGSYHC----ICKTGYTPDIT-GTSCVDLNECNQAPKPC--NF 2457
C CR GE C+N GS+ C C TGY ++T SC D++EC C +F
Sbjct: 220 CITGSHSCRLGESCINTVGSFRCQRDSSCGTGY--ELTEDNSCKDIDECESGIHNCLPDF 277
Query: 2458 ICKNTEGSYQC----SCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCK- 2510
IC+NT GS++C C G+I G +C D++EC + C C+NT G +TC+
Sbjct: 278 ICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQK 336
Query: 2511 ----CPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSS 2564
C G+ + T C+D +EC CG C N+PGSF CEC+ G+ D
Sbjct: 337 NVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM 396
Query: 2565 CEDVDECE--GNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASC 2622
C DV+EC+ C H C+N +G Y CSC G+ C D NEC S+ C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC--SQEC 454
Query: 2623 HNTLGSYKCMCPAGFQYEQFSG-GCQDINECG--SAQAPCSYGCSNTEGGYLCGCPPGYF 2679
N GSY+C C G+Q G C+DI+EC + CSY C N G + C CP +
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Query: 2680 RIGQG--------HCVSGM 2690
R+ CV+G+
Sbjct: 515 RLAPNGRNCQDIDECVTGI 533
Score = 196 bits (497), Expect = 4e-49
Identities = 174/601 (28%), Positives = 243/601 (40%), Gaps = 120/601 (19%)
Query: 1958 CNEGYEVAPDGRTC-----VDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE 2012
C +G+ +A + C + EC + +C + L C G SL NE+
Sbjct: 37 CADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELH------CATGISLANEQ-- 88
Query: 2013 DIDECVEEPEICALGTCSNTEGSF--KCL--CPEGFSLSSSGRRCQDLRMSYCYAKFEGG 2068
D C G ++ E +F +C C G + + G+ C+ Y+ G
Sbjct: 89 --DRCATPH-----GDNASLEATFVKRCCHCCLLGRAAQAQGQSCE-------YSLMVGY 134
Query: 2069 KCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDM 2128
+C C +K + GD E D+ + +
Sbjct: 135 QCGQVFR--------ACCVKSQETGDLDVGGLQETDKIIE---------VEEEQEDPYLN 177
Query: 2129 DECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGN-PCGNG-TCKNV 2184
D C+ CK QC +T C C GY L G C D +EC G+ C G +C N
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2185 IGGFEC----TCEEGFEPGPMMTCEDINECAQNPLLCA--FRCVNTYGSYECK----CPV 2234
+G F C +C G+E +C+DI+EC C F C NT GS+ C+ C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 2235 GYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI-----CGPGYQRRPDGEGC 2289
G++ ++ C D +EC C C N G+Y C CG GY +G C
Sbjct: 297 GFI-QDALGNCIDINECLSISAPCPIGHT-CINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 2290 VDENECQTKPGICENG-RCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMC 2348
VD +EC C G RC+N+ GS+ CEC G+ + + + MC
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY-----------------YFDGISRMC 397
Query: 2349 QIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG-----ADI 2403
V +EC GR G CE LC GF + DI
Sbjct: 398 ---------VDVNECQRYPGRLCGHKCE------NTLGSYLCSCSVGFRLSVDGRSCEDI 442
Query: 2404 DECKVIHDVCRNGECVNDRGSYHCICKTGYT-PDITGTSCVDLNECN--QAPKPCNFICK 2460
+EC C EC N GSY C C+ GY D+ G +C D++EC C++ C
Sbjct: 443 NECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCI 499
Query: 2461 NTEGSYQCSCPK-GYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTC---KCPPG 2514
N GS+QCSCP GY L +GR+C+D+DEC T HNC C N GGF C +CP
Sbjct: 500 NIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 559
Query: 2515 F 2515
+
Sbjct: 560 Y 560
Score = 194 bits (492), Expect = 1e-48
Identities = 151/487 (31%), Positives = 213/487 (43%), Gaps = 79/487 (16%)
Query: 1717 KMCCCSYNIGRAWNKPCEQCPIPST------DEFATLCGSQRPGFVIDI----YTGLPVD 1766
K CC +GRA + C F C + +D+ T ++
Sbjct: 107 KRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIE 166
Query: 1767 IDECREIPGV---CENG-----VCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-V 1817
++E +E P + C G C + C C VG+ + CED++EC G
Sbjct: 167 VEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 1818 CQRNAECINTAGSYRCD----CKPGYRFTSTGQCNDRNECQE-IPNICSHGQCIDTVGSF 1872
C+ CINT GS+RC C GY T C D +EC+ I N C +T+GSF
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSF 286
Query: 1873 YCL----CHTGFKTNDDQTMCLDINECERDA--CGNG-TCRNTIGSFNCR-----CNHGF 1920
C C +GF D C+DINEC + C G TC NT GS+ C+ C G+
Sbjct: 287 RCRPKLQCKSGF-IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 1921 ILSHNND-CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLL 1979
L+ C+DVDECA + +C+N+ GSF+C+C GY R CVD+NEC
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 1980 EPRKCAPGTCQNLDGSYRCICPPGY--SLQNEKCEDIDECVEEPEICALGTCSNTEGSFK 2037
P + C+N GSY C C G+ S+ CEDI+EC P C+ C+N GS++
Sbjct: 406 YPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQ 462
Query: 2038 CLCPEGFSLSS-SGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPC 2096
C C G+ LS G C+D+ +C+ P + H C + G
Sbjct: 463 CYCRRGYQLSDVDGVTCEDI-----------DECALP-TGGHICSYRCINIPG------- 503
Query: 2097 ELCPTEPDEAFRQICPYGSGIIVGPDD-SAVDMDECKE--PDVCKHGQCINTDGSYRC-- 2151
+F+ CP SG + P+ + D+DEC + + C N G +RC
Sbjct: 504 ---------SFQCSCP-SSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLA 553
Query: 2152 -ECPFGY 2157
ECP Y
Sbjct: 554 FECPENY 560
Score = 175 bits (444), Expect = 5e-43
Identities = 152/499 (30%), Positives = 212/499 (42%), Gaps = 100/499 (20%)
Query: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRG-----ECIDVDECEKNP-----CA 500
+Y +V Y C G+ +C + + LD+ G + I+V+E +++P C
Sbjct: 127 EYSLMVGYQC--GQVFR---ACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCR 181
Query: 501 GG-----ECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGR-CINTDGSFH 554
GG +C + C C GYQ C D++EC+ C G CINT GSF
Sbjct: 182 GGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 555 C----VCNAGFHVTRDGKNCEDMDEC--SIRNMCLNGMCINEDGSFKC----ICKPGFQL 604
C C G+ +T D +C+D+DEC I N + +C N GSF+C CK GF
Sbjct: 242 CQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 605 ASDGRYCKDINEC-ETPGICMNGR-CVNTDGSYRCE-----CFPGLAVGLDGRVCVDTHM 657
+ G C DINEC C G C+NT+GSY C+ C G + +G CVD
Sbjct: 301 DALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV-- 357
Query: 658 RSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG--- 714
EC + G C P ++ C +G
Sbjct: 358 -----------------------DECAPPAEPCGKGHRCVNSP----GSFRCECKTGYYF 390
Query: 715 PGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSL 774
G++ D+NEC P CEN G+Y C C+ G+ + G++C DINEC +S
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSS 448
Query: 775 LCDNGQCRNTPGSFVCTCPKGF-IYKPDLKTCEDIDECESSPCINGVCK----NSPGSFI 829
C +C N GS+ C C +G+ + D TCEDIDEC + P +C N PGSF
Sbjct: 449 PCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDEC-ALPTGGHICSYRCINIPGSFQ 506
Query: 830 CEC-SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCT 888
C C SS L P C + ID C I+ ++ C + G G C
Sbjct: 507 CSCPSSGYRLAPNGRNCQD----------ID-ECVTGIHNCSINETCFNIQG---GFRCL 552
Query: 889 LCQVDPICGKGYSRIKGTQ 907
+ C + Y R TQ
Sbjct: 553 AFE----CPENYRRSAATQ 567
Score = 166 bits (421), Expect = 2e-40
Identities = 135/430 (31%), Positives = 188/430 (43%), Gaps = 73/430 (16%)
Query: 532 DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC--SIRNMCLNGMCIN 589
D C + G C +C +T C C G+ + DG +CED++EC + L CIN
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 590 EDGSFKC----ICKPGFQLASDGRYCKDINECETPGI--CM-NGRCVNTDGSYRCECFPG 642
GSF+C C G++L D CKDI+ECE+ GI C+ + C NT GS+RC
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNS-CKDIDECES-GIHNCLPDFICQNTLGSFRCR---- 289
Query: 643 LAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQ 702
+ C G+ + L + +EC S G C
Sbjct: 290 --------------PKLQCKSGFIQDA----LGNCIDINECLSISAPCPIGHTCINTEGS 331
Query: 703 NSAEYQAL-CSSGPGMTSAGS---DINECALDPDICPNGI-CENLRGTYKCICNSGYEVD 757
+ + C G + G+ D++ECA + C G C N G+++C C +GY D
Sbjct: 332 YTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 758 STGKNCVDINECV-LNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPC 816
+ CVD+NEC LC + +C NT GS++C+C GF D ++CEDI+EC SSPC
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC 450
Query: 817 INGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQT---VIDGRCEININGATLKS 873
+ C N GS+ C C L + E I T + RC INI G + +
Sbjct: 451 -SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRC-INIPG-SFQC 507
Query: 874 QCCSSLGAAWGSPCTLCQVDPICGKGYSRI-KGTQCEDIDECEVFPGVCK-NGLCVNTRG 931
C SS GY G C+DIDEC C N C N +G
Sbjct: 508 SCPSS--------------------GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 932 SFKC---QCP 938
F+C +CP
Sbjct: 548 GFRCLAFECP 557
Score = 166 bits (419), Expect = 4e-40
Identities = 136/437 (31%), Positives = 178/437 (40%), Gaps = 110/437 (25%)
Query: 780 QCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLD 839
QCR+T VC+C G+ D +CED++EC + GS C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECIT------------GSHSCR-------- 228
Query: 840 PTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKG 899
L C +++G+ CQ D CG G
Sbjct: 229 -------------------------------LGESCINTVGSF------RCQRDSSCGTG 251
Query: 900 YSRIKGTQCEDIDECEVFPGVC-KNGLCVNTRGSFKC----QCPSGMTLDATGRICLDIR 954
Y + C+DIDECE C + +C NT GSF+C QC SG DA G C+DI
Sbjct: 252 YELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDIN 310
Query: 955 L-----------ETCFLRYEDEEC--TLPIAGR----HRMDACCCSVGAAWGTEECEECP 997
TC C +P GR + C V +EC P
Sbjct: 311 ECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV------DEC--AP 362
Query: 998 MRNTPEYEELCPRGPGFATKEITNGKPF------FKDINECKMIPS-LCTHGKCRNTIGS 1050
C PG E G F D+NEC+ P LC H KC NT+GS
Sbjct: 363 PAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGS 421
Query: 1051 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKN 1110
+ C C GF L + R+C DI+EC SP C + +C N G ++C C GY+ +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVT 478
Query: 1111 CMDIDECQRDPLLCRGG-----VCHNTEGSYRCECP-PGHQLSPNISACIDINECELSAH 1164
C DIDEC L GG C N GS++C CP G++L+PN C DI+EC H
Sbjct: 479 CEDIDEC----ALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIH 534
Query: 1165 LCP-NGRCVNLIGKYQC 1180
C N C N+ G ++C
Sbjct: 535 NCSINETCFNIQGGFRC 551
Score = 155 bits (391), Expect = 7e-37
Identities = 141/458 (30%), Positives = 183/458 (39%), Gaps = 100/458 (21%)
Query: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSENLNLCGNGQ-CL 1421
D C G C Q C++T C C GY DG +C D++EC + C G+ C+
Sbjct: 178 DRCRGGGP-CKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 1422 NAPGGYRCE----CDMGFVPSADGKACEDIDECS--LPNICVFGTCHNLPGLFRC----E 1471
N G +RC+ C G+ + D +C+DIDEC + N C N G FRC +
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 1472 CEIGYELDRSGGNCTDVNECLDPTT-CISGN-CVNTPGSYIC-----DCPPDFELNPTRV 1524
C+ G+ D G NC D+NECL + C G+ C+NT GSY C +C + LN
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 1525 GCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSE 1584
CVD C P G C N G C C G + MC
Sbjct: 353 RCVDV--DECAPPAEPCGKGH--RCVNSPG----SFRCECKTGYYFDGISRMCV------ 398
Query: 1585 YKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTR 1644
D++ECQ PG G KC NT GS+ C C G+ L+ D R
Sbjct: 399 ---------------------DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGR 437
Query: 1645 VCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQ 1704
C+D+NEC + C C N G+Y C C RR Y+ D
Sbjct: 438 SCEDINECSS-SPCSQ-ECANVYGSYQCYC----------------RRG--YQLSDVDGV 477
Query: 1705 TCDGELLFNMTKKMCCCSYNIGRAWNKPCE-QCPIPSTDEFATLCGSQRPGFVIDIYTGL 1763
TC+ + CSY R N P QC PS+ G+ +
Sbjct: 478 TCEDIDECALPTGGHICSY---RCINIPGSFQCSCPSS------------GYRLAPNGRN 522
Query: 1764 PVDIDEC-REIPGVCENGVCINMVGSFRC---ECPVGF 1797
DIDEC I N C N+ G FRC ECP +
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 136 bits (343), Expect = 3e-31
Identities = 124/427 (29%), Positives = 176/427 (41%), Gaps = 94/427 (22%)
Query: 1470 CECEIGYELDRSGGNCTDVNECLDPT-TCISG-NCVNTPGSYICD----CPPDFELNPTR 1523
C C +GY+L G +C DVNEC+ + +C G +C+NT GS+ C C +EL
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYEL---- 254
Query: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS 1583
T +C DI C + I + C +LG P C +
Sbjct: 255 -----TEDNSCK-DI--------DECESGIHNCLPDFICQNTLGSFRCRPKLQCKS---- 296
Query: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCR-----CPTGY 1637
GF + + + DI+EC + C G CINT GS+ C+ C GY
Sbjct: 297 ----------GFIQDALGNCI-DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 1638 YLNEDTRVCDDVNECETPGI-CGPG-TCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLC 1695
+LNE+ C DV+EC P CG G C N+ G++ C C Y C+D+
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 1696 YRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGF 1755
Y + C + + +C CS GF
Sbjct: 406 Y-----PGRLCGHKCENTLGSYLCSCSV------------------------------GF 430
Query: 1756 VIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYND-KLLVCEDIDEC-- 1812
+ + DI+EC P E C N+ GS++C C G+ +D + CEDIDEC
Sbjct: 431 RLSVDGRSCEDINECSSSPCSQE---CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECAL 487
Query: 1813 -QNGPVCQRNAECINTAGSYRCDC-KPGYRFTSTGQ-CNDRNECQEIPNICSHGQ-CIDT 1868
G +C + CIN GS++C C GYR G+ C D +EC + CS + C +
Sbjct: 488 PTGGHIC--SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNI 545
Query: 1869 VGSFYCL 1875
G F CL
Sbjct: 546 QGGFRCL 552
Score = 103 bits (258), Expect = 2e-21
Identities = 85/302 (28%), Positives = 112/302 (37%), Gaps = 64/302 (21%)
Query: 118 HCNIRCMNGGSCSDDH--------CLCQKGYI----GTHC--------GQPVCESG--CL 155
+ N RC GG C C C GY G C G C G C+
Sbjct: 175 YLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 156 N---GGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQM----CQGQLSGIVCTKTL 208
N RC + C Y T +D C + I N + CQ L C L
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDI--DECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 209 CCAT--VGRAWGH------------PCEM------------CPAQPHPCRRGFIPNIRTG 242
C + + A G+ PC + C C RG+ N
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 243 ACQDVDECQAIPGLC-QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG 301
C DVDEC C +G C+N+ GSF C+C G+ + +S+ C D++EC PG G
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 302 GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCD 361
+C NT+ SY C C GF S DG C D+ ++ CS + QC C
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCEDI------NECSSSPCSQECANVYGSYQCYCR 466
Query: 362 AG 363
G
Sbjct: 467 RG 468
Score = 89.4 bits (220), Expect = 5e-17
Identities = 86/284 (30%), Positives = 125/284 (44%), Gaps = 51/284 (17%)
Query: 84 ICRHSCGDGFCSRPNMCTCPSGQIAPSCGSR-SIQHC---NIRCMNGGSC--SDDHCLCQ 137
IC+++ G C RP + C SG I + G+ I C + C G +C ++ CQ
Sbjct: 278 ICQNTLGSFRC-RPKL-QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQ 335
Query: 138 KGYIGTHCGQPVCESG--CLNGGRCVAP-------NRCACTYGFTGPQCERDYRTGPCFT 188
K G + E G C++ C P +RC + G +C +TG F
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC----KTGYYFD 391
Query: 189 VISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCE------MCPAQPHPCRRGFIPNIRTG 242
IS +MC C GR GH CE +C C GF ++
Sbjct: 392 GIS-RMC--------VDVNECQRYPGRLCGHKCENTLGSYLCS-----CSVGFRLSVDGR 437
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEV-SQKCEDIDECSTIPG--IC 299
+C+D++EC + P C C N GS++C C G++L++V CEDIDEC+ G IC
Sbjct: 438 SCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC 494
Query: 300 EGGECTNTVSSYFCKCP-PGFYTSPDGTRCIDVRPGYCYTALTN 342
C N S+ C CP G+ +P+G C D+ C T + N
Sbjct: 495 -SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI--DECVTGIHN 535
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 244 bits (624), Expect = 7e-64
Identities = 176/545 (32%), Positives = 245/545 (44%), Gaps = 91/545 (16%)
Query: 1005 EELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSE 1064
E C G AT + P+ + EC+M+ C H + + C +G +L +E
Sbjct: 34 EACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLE------ELHCATGISLANE 87
Query: 1065 ERNC------------TDIDECRISPDLCGRGQCVNTPG-DFECKCDEGYESGFMMMKNC 1111
+ C T + C C G+ G E GY+ G + C
Sbjct: 88 QDRCATPHGDNASLEATFVKRC---CHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACC 144
Query: 1112 --------------------MDIDECQRDPLL---CRGG-----VCHNTEGSYRCECPPG 1143
++++E Q DP L CRGG C +T C C G
Sbjct: 145 VKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVG 204
Query: 1144 HQLSPNISACIDINECELSAHLCPNGR-CVNLIGKYQC----ACNPGYHSTPDRLFCVDI 1198
+QL + +C D+NEC +H C G C+N +G ++C +C GY T D C DI
Sbjct: 205 YQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDI 263
Query: 1199 DECSIMNGGC--ETFCTNSEGSYEC----SCQPGFALMPDQRSCTDIDECEDNPNICD-G 1251
DEC C + C N+ GS+ C C+ GF + +C DI+EC C G
Sbjct: 264 DECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF-IQDALGNCIDINECLSISAPCPIG 322
Query: 1252 GQCTNIPGEYRCL-----CYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFIC 1305
C N G Y C C G+ +E+ CVDV+EC C G C N+ GSF C
Sbjct: 323 HTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRC 382
Query: 1306 HCDMGYSGKKGKTGCTDINECE-IGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCT 1362
C GY C D+NEC+ CG C NT GS+ CSCS G+ DG C
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCE 440
Query: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY---TGDGFTCTDLDECS--ENLNLCGN 1417
D++ECS+ CSQ +C N GSY+C C+ GY DG TC D+DEC+ ++C +
Sbjct: 441 DINECSSSP--CSQ--ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-S 495
Query: 1418 GQCLNAPGGYRCEC-DMGFVPSADGKACEDIDEC--SLPNICVFGTCHNLPGLFRC---E 1471
+C+N PG ++C C G+ + +G+ C+DIDEC + N + TC N+ G FRC E
Sbjct: 496 YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFE 555
Query: 1472 CEIGY 1476
C Y
Sbjct: 556 CPENY 560
Score = 225 bits (574), Expect = 4e-58
Identities = 140/386 (36%), Positives = 194/386 (50%), Gaps = 41/386 (10%)
Query: 1085 QCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCE---- 1139
QC +T + C C GY+ +C D++EC CR G C NT GS+RC+
Sbjct: 189 QCRDTGDEVVCSCFVGYQL-LSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSS 247
Query: 1140 CPPGHQLSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCA----CNPGYHSTPDRLF 1194
C G++L+ + ++C DI+ECE H C P+ C N +G ++C C G+ D L
Sbjct: 248 CGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF--IQDALG 304
Query: 1195 -CVDIDECSIMNGGCET--FCTNSEGSYEC-----SCQPGFALMPDQRSCTDIDECEDNP 1246
C+DI+EC ++ C C N+EGSY C +C G+ L + C D+DEC
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 1247 NICDGG-QCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFIC 1305
C G +C N PG +RC C G+ + CVDVNEC P CENT GS++C
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLC 424
Query: 1306 HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW---IGDGIKCT 1362
C +G+ C DINEC + C + C N GS++C C G+ DG+ C
Sbjct: 425 SCSVGFRLSVDGRSCEDINEC--SSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 1363 DLDECS--NGTHMCSQHADCKNTMGSYRCLC-KEGY--TGDGFTCTDLDECSENLNLCG- 1416
D+DEC+ G H+CS C N GS++C C GY +G C D+DEC ++ C
Sbjct: 481 DIDECALPTGGHICSYR--CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 1417 NGQCLNAPGGYRC---ECDMGFVPSA 1439
N C N GG+RC EC + SA
Sbjct: 539 NETCFNIQGGFRCLAFECPENYRRSA 564
Score = 218 bits (555), Expect = 7e-56
Identities = 180/611 (29%), Positives = 246/611 (40%), Gaps = 116/611 (18%)
Query: 1121 PLLCRGGVCHNTEGS-----YRCECPPGHQLSPNISAC-----IDINECELSAHLCPNGR 1170
PLL GG+ G C GH+++ + C + EC + C
Sbjct: 13 PLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQC---- 68
Query: 1171 CVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALM 1230
C + + + CA + DR D S+ + C C C G A
Sbjct: 69 CHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCC-------HC-CLLGRAAQ 120
Query: 1231 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASE-------DMKTCVDVNE 1283
+SC ++ G QC + +R C + + ++V E
Sbjct: 121 AQGQSC--------EYSLMVGYQCGQV---FRACCVKSQETGDLDVGGLQETDKIIEVEE 169
Query: 1284 CDLNPNI---CLSG-----TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK 1335
+P + C G C +T +C C +GY C D+NEC G+H+C
Sbjct: 170 EQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRL 229
Query: 1336 HAVCTNTAGSFKC----SCSPGW-IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL 1390
C NT GSF+C SC G+ + + C D+DEC +G H C C+NT+GS+RC
Sbjct: 230 GESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCR 289
Query: 1391 ----CKEGYTGDGF-TCTDLDECSENLNLCGNGQ-CLNAPGGYRCE-----CDMGFVPSA 1439
CK G+ D C D++EC C G C+N G Y C+ C G+ +
Sbjct: 290 PKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNE 349
Query: 1440 DGKACEDIDECSLP-NICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTT 1496
+G C D+DEC+ P C G C N PG FRCEC+ GY D C DVNEC P
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
C NT GSY+C C F L+ C D + + CS E
Sbjct: 410 LCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN------------ECSSSPCSQECANV 457
Query: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPG- 1615
C C G Y++ G V EDIDEC G
Sbjct: 458 YGSYQCYCRRG-----------------YQLSDVDG---------VTCEDIDECALPTGG 491
Query: 1616 -LCQGGKCINTFGSFQCRCP-TGYYLNEDTRVCDDVNECETPGI--CGPG-TCYNTVGNY 1670
+C +CIN GSFQC CP +GY L + R C D++EC T GI C TC+N G +
Sbjct: 492 HICSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVT-GIHNCSINETCFNIQGGF 549
Query: 1671 TCI---CPPDY 1678
C+ CP +Y
Sbjct: 550 RCLAFECPENY 560
Score = 213 bits (542), Expect = 2e-54
Identities = 156/479 (32%), Positives = 220/479 (45%), Gaps = 71/479 (14%)
Query: 1109 KNCMDIDE----CQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAH 1164
K C + E Q + L C G+ E RC P G +A ++ + H
Sbjct: 59 KECRMVQEQCCHSQLEELHCATGISLANEQD-RCATPHGD------NASLEATFVKRCCH 111
Query: 1165 LCPNGRCVNLIGK---------YQC-----AC----------NPGYHSTPDRLFCVDID- 1199
C GR G+ YQC AC + G D++ V+ +
Sbjct: 112 CCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ 171
Query: 1200 ECSIMN------GGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQ 1253
E +N G C+ C ++ CSC G+ L+ D SC D++EC + C G+
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGE 231
Query: 1254 -CTNIPGEYRCL----CYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFICH- 1306
C N G +RC C G+ +ED +C D++EC+ + CL C+NT GSF C
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRP 290
Query: 1307 ---CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-----SCSPGWI--G 1356
C G+ + C DINEC + C C NT GS+ C +C G+
Sbjct: 291 KLQCKSGFI-QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNE 349
Query: 1357 DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFT--CTDLDECSENLN- 1413
+G +C D+DEC+ C + C N+ GS+RC CK GY DG + C D++EC
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECE 1473
LCG+ +C N G Y C C +GF S DG++CEDI+ECS + C N+ G ++C C
Sbjct: 410 LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCR 466
Query: 1474 IGYEL-DRSGGNCTDVNECLDPT--TCISGNCVNTPGSYICDCPPD-FELNPTRVGCVD 1528
GY+L D G C D++EC PT S C+N PGS+ C CP + L P C D
Sbjct: 467 RGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQD 525
Score = 208 bits (530), Expect = 5e-53
Identities = 145/408 (35%), Positives = 189/408 (46%), Gaps = 56/408 (13%)
Query: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
G C+ +C +T C C G+ + C D E C T + C++G S N V
Sbjct: 184 GPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNE--CITG--SHSCRLGESCINTVG 238
Query: 2360 KSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKV-IHDVCRNGEC 2418
C D G G + C DIDEC+ IH+ + C
Sbjct: 239 SFRCQRDSSCGTGYE---------LTEDNSCK----------DIDECESGIHNCLPDFIC 279
Query: 2419 VNDRGSYHCI----CKTGYTPDITGTSCVDLNECNQ--APKPCNFICKNTEGSYQC---- 2468
N GS+ C CK+G+ D G +C+D+NEC AP P C NTEGSY C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 2469 -SCPKGYILQEDGRSCKDLDECATKQHNCQ--FLCVNTIGGFTCKCPPGFTQHHTS--CI 2523
+C +GY L E+G C D+DECA C CVN+ G F C+C G+ S C+
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 2524 DNNECTS-DINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQ 2582
D NEC LCG K C+NT GS+ C C GF L G SCED++EC + C C
Sbjct: 399 DVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQECA 455
Query: 2583 NIIGGYRCSCPQGY-LQHYQWNQCVDENECL---SAHICGGASCHNTLGSYKCMCPA-GF 2637
N+ G Y+C C +GY L C D +EC HIC C N GS++C CP+ G+
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCSCPSSGY 514
Query: 2638 QYEQFSGGCQDINECGSAQAPCSYG--CSNTEGGYLC---GCPPGYFR 2680
+ CQDI+EC + CS C N +GG+ C CP Y R
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRR 562
Score = 207 bits (526), Expect = 2e-52
Identities = 135/415 (32%), Positives = 186/415 (44%), Gaps = 58/415 (13%)
Query: 2168 DECSVGNPCGNGTCKNVIGGFECTCEEGFEP-GPMMTCEDINECAQNPLLCAF--RCVNT 2224
D C G PC C++ C+C G++ ++CED+NEC C C+NT
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2225 YGSYECK----CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI----C 2276
GS+ C+ C GY L ED CKD DECE G H+C + C+N +G++ C C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFI-CQNTLGSFRCRPKLQC 294
Query: 2277 GPGYQRRPDGEGCVDENECQTKPGICENGR-CLNTRGSYTCE-----CNDGFTASPNQDE 2330
G+ + G C+D NEC + C G C+NT GSYTC+ C G+ +
Sbjct: 295 KSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 2331 CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLC 2390
C+D E C C G N C C G + +C
Sbjct: 354 CVDVDE--CAPPA--EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC------------ 397
Query: 2391 PHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQ 2450
D++EC+ +C N GSY C C G+ + G SC D+NEC+
Sbjct: 398 ----------VDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 2451 APKPCNFICKNTEGSYQCSCPKGYILQE-DGRSCKDLDECA--TKQHNCQFLCVNTIGGF 2507
+P C+ C N GSYQC C +GY L + DG +C+D+DECA T H C + C+N G F
Sbjct: 448 SP--CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSF 505
Query: 2508 TCKCPPG---FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC---ECQRGF 2556
C CP + +C D +EC + I+ C C N G F C EC +
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 198 bits (503), Expect = 7e-50
Identities = 126/379 (33%), Positives = 176/379 (46%), Gaps = 48/379 (12%)
Query: 2349 QIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA---DIDE 2405
++ +P C RG GP + C G C G +++G D++E
Sbjct: 166 EVEEEQEDPYLNDRC-----RGGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNE 219
Query: 2406 CKVIHDVCRNGE-CVNDRGSYHC----ICKTGYTPDIT-GTSCVDLNECNQAPKPC--NF 2457
C CR GE C+N GS+ C C TGY ++T SC D++EC C +F
Sbjct: 220 CITGSHSCRLGESCINTVGSFRCQRDSSCGTGY--ELTEDNSCKDIDECESGIHNCLPDF 277
Query: 2458 ICKNTEGSYQC----SCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCK- 2510
IC+NT GS++C C G+I G +C D++EC + C C+NT G +TC+
Sbjct: 278 ICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQK 336
Query: 2511 ----CPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSS 2564
C G+ + T C+D +EC CG C N+PGSF CEC+ G+ D
Sbjct: 337 NVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM 396
Query: 2565 CEDVDECE--GNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASC 2622
C DV+EC+ C H C+N +G Y CSC G+ C D NEC S+ C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC--SQEC 454
Query: 2623 HNTLGSYKCMCPAGFQYEQFSG-GCQDINECG--SAQAPCSYGCSNTEGGYLCGCPPGYF 2679
N GSY+C C G+Q G C+DI+EC + CSY C N G + C CP +
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Query: 2680 RIGQG--------HCVSGM 2690
R+ CV+G+
Sbjct: 515 RLAPNGRNCQDIDECVTGI 533
Score = 196 bits (497), Expect = 4e-49
Identities = 174/601 (28%), Positives = 243/601 (40%), Gaps = 120/601 (19%)
Query: 1958 CNEGYEVAPDGRTC-----VDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE 2012
C +G+ +A + C + EC + +C + L C G SL NE+
Sbjct: 37 CADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELH------CATGISLANEQ-- 88
Query: 2013 DIDECVEEPEICALGTCSNTEGSF--KCL--CPEGFSLSSSGRRCQDLRMSYCYAKFEGG 2068
D C G ++ E +F +C C G + + G+ C+ Y+ G
Sbjct: 89 --DRCATPH-----GDNASLEATFVKRCCHCCLLGRAAQAQGQSCE-------YSLMVGY 134
Query: 2069 KCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDM 2128
+C C +K + GD E D+ + +
Sbjct: 135 QCGQVFR--------ACCVKSQETGDLDVGGLQETDKIIE---------VEEEQEDPYLN 177
Query: 2129 DECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGN-PCGNG-TCKNV 2184
D C+ CK QC +T C C GY L G C D +EC G+ C G +C N
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2185 IGGFEC----TCEEGFEPGPMMTCEDINECAQNPLLCA--FRCVNTYGSYECK----CPV 2234
+G F C +C G+E +C+DI+EC C F C NT GS+ C+ C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 2235 GYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI-----CGPGYQRRPDGEGC 2289
G++ ++ C D +EC C C N G+Y C CG GY +G C
Sbjct: 297 GFI-QDALGNCIDINECLSISAPCPIGHT-CINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 2290 VDENECQTKPGICENG-RCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMC 2348
VD +EC C G RC+N+ GS+ CEC G+ + + + MC
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY-----------------YFDGISRMC 397
Query: 2349 QIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG-----ADI 2403
V +EC GR G CE LC GF + DI
Sbjct: 398 ---------VDVNECQRYPGRLCGHKCE------NTLGSYLCSCSVGFRLSVDGRSCEDI 442
Query: 2404 DECKVIHDVCRNGECVNDRGSYHCICKTGYT-PDITGTSCVDLNECN--QAPKPCNFICK 2460
+EC C EC N GSY C C+ GY D+ G +C D++EC C++ C
Sbjct: 443 NECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCI 499
Query: 2461 NTEGSYQCSCPK-GYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTC---KCPPG 2514
N GS+QCSCP GY L +GR+C+D+DEC T HNC C N GGF C +CP
Sbjct: 500 NIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 559
Query: 2515 F 2515
+
Sbjct: 560 Y 560
Score = 194 bits (492), Expect = 1e-48
Identities = 151/487 (31%), Positives = 213/487 (43%), Gaps = 79/487 (16%)
Query: 1717 KMCCCSYNIGRAWNKPCEQCPIPST------DEFATLCGSQRPGFVIDI----YTGLPVD 1766
K CC +GRA + C F C + +D+ T ++
Sbjct: 107 KRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIE 166
Query: 1767 IDECREIPGV---CENG-----VCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-V 1817
++E +E P + C G C + C C VG+ + CED++EC G
Sbjct: 167 VEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 1818 CQRNAECINTAGSYRCD----CKPGYRFTSTGQCNDRNECQE-IPNICSHGQCIDTVGSF 1872
C+ CINT GS+RC C GY T C D +EC+ I N C +T+GSF
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSF 286
Query: 1873 YCL----CHTGFKTNDDQTMCLDINECERDA--CGNG-TCRNTIGSFNCR-----CNHGF 1920
C C +GF D C+DINEC + C G TC NT GS+ C+ C G+
Sbjct: 287 RCRPKLQCKSGF-IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 1921 ILSHNND-CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLL 1979
L+ C+DVDECA + +C+N+ GSF+C+C GY R CVD+NEC
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 1980 EPRKCAPGTCQNLDGSYRCICPPGY--SLQNEKCEDIDECVEEPEICALGTCSNTEGSFK 2037
P + C+N GSY C C G+ S+ CEDI+EC P C+ C+N GS++
Sbjct: 406 YPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQ 462
Query: 2038 CLCPEGFSLSS-SGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPC 2096
C C G+ LS G C+D+ +C+ P + H C + G
Sbjct: 463 CYCRRGYQLSDVDGVTCEDI-----------DECALP-TGGHICSYRCINIPG------- 503
Query: 2097 ELCPTEPDEAFRQICPYGSGIIVGPDD-SAVDMDECKE--PDVCKHGQCINTDGSYRC-- 2151
+F+ CP SG + P+ + D+DEC + + C N G +RC
Sbjct: 504 ---------SFQCSCP-SSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLA 553
Query: 2152 -ECPFGY 2157
ECP Y
Sbjct: 554 FECPENY 560
Score = 173 bits (439), Expect = 2e-42
Identities = 135/425 (31%), Positives = 188/425 (44%), Gaps = 81/425 (19%)
Query: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRG-----ECIDVDECEKNP-----CA 500
+Y +V Y C G+ +C + + LD+ G + I+V+E +++P C
Sbjct: 127 EYSLMVGYQC--GQVFR---ACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCR 181
Query: 501 GG-----ECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGR-CINTDGSFH 554
GG +C + C C GYQ C D++EC+ C G CINT GSF
Sbjct: 182 GGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 555 C----VCNAGFHVTRDGKNCEDMDEC--SIRNMCLNGMCINEDGSFKC----ICKPGFQL 604
C C G+ +T D +C+D+DEC I N + +C N GSF+C CK GF
Sbjct: 242 CQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 605 ASDGRYCKDINEC-ETPGICMNGR-CVNTDGSYRCE-----CFPGLAVGLDGRVCVDTHM 657
+ G C DINEC C G C+NT+GSY C+ C G + +G CVD
Sbjct: 301 DALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV-- 357
Query: 658 RSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG--- 714
EC + G C P ++ C +G
Sbjct: 358 -----------------------DECAPPAEPCGKGHRCVNSP----GSFRCECKTGYYF 390
Query: 715 PGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSL 774
G++ D+NEC P CEN G+Y C C+ G+ + G++C DINEC +S
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSS 448
Query: 775 LCDNGQCRNTPGSFVCTCPKGF-IYKPDLKTCEDIDECESSPCINGVCK----NSPGSFI 829
C +C N GS+ C C +G+ + D TCEDIDEC + P +C N PGSF
Sbjct: 449 PCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDEC-ALPTGGHICSYRCINIPGSFQ 506
Query: 830 CECSS 834
C C S
Sbjct: 507 CSCPS 511
Score = 166 bits (421), Expect = 2e-40
Identities = 135/430 (31%), Positives = 188/430 (43%), Gaps = 73/430 (16%)
Query: 532 DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC--SIRNMCLNGMCIN 589
D C + G C +C +T C C G+ + DG +CED++EC + L CIN
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 590 EDGSFKC----ICKPGFQLASDGRYCKDINECETPGI--CM-NGRCVNTDGSYRCECFPG 642
GSF+C C G++L D CKDI+ECE+ GI C+ + C NT GS+RC
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNS-CKDIDECES-GIHNCLPDFICQNTLGSFRCR---- 289
Query: 643 LAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQ 702
+ C G+ + L + +EC S G C
Sbjct: 290 --------------PKLQCKSGFIQDA----LGNCIDINECLSISAPCPIGHTCINTEGS 331
Query: 703 NSAEYQAL-CSSGPGMTSAGS---DINECALDPDICPNGI-CENLRGTYKCICNSGYEVD 757
+ + C G + G+ D++ECA + C G C N G+++C C +GY D
Sbjct: 332 YTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 758 STGKNCVDINECV-LNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPC 816
+ CVD+NEC LC + +C NT GS++C+C GF D ++CEDI+EC SSPC
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC 450
Query: 817 INGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQT---VIDGRCEININGATLKS 873
+ C N GS+ C C L + E I T + RC INI G + +
Sbjct: 451 -SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRC-INIPG-SFQC 507
Query: 874 QCCSSLGAAWGSPCTLCQVDPICGKGYSRI-KGTQCEDIDECEVFPGVCK-NGLCVNTRG 931
C SS GY G C+DIDEC C N C N +G
Sbjct: 508 SCPSS--------------------GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 932 SFKC---QCP 938
F+C +CP
Sbjct: 548 GFRCLAFECP 557
Score = 166 bits (419), Expect = 4e-40
Identities = 136/437 (31%), Positives = 178/437 (40%), Gaps = 110/437 (25%)
Query: 780 QCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLD 839
QCR+T VC+C G+ D +CED++EC + GS C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECIT------------GSHSCR-------- 228
Query: 840 PTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKG 899
L C +++G+ CQ D CG G
Sbjct: 229 -------------------------------LGESCINTVGSF------RCQRDSSCGTG 251
Query: 900 YSRIKGTQCEDIDECEVFPGVC-KNGLCVNTRGSFKC----QCPSGMTLDATGRICLDIR 954
Y + C+DIDECE C + +C NT GSF+C QC SG DA G C+DI
Sbjct: 252 YELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDIN 310
Query: 955 L-----------ETCFLRYEDEEC--TLPIAGR----HRMDACCCSVGAAWGTEECEECP 997
TC C +P GR + C V +EC P
Sbjct: 311 ECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV------DEC--AP 362
Query: 998 MRNTPEYEELCPRGPGFATKEITNGKPF------FKDINECKMIPS-LCTHGKCRNTIGS 1050
C PG E G F D+NEC+ P LC H KC NT+GS
Sbjct: 363 PAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGS 421
Query: 1051 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKN 1110
+ C C GF L + R+C DI+EC SP C + +C N G ++C C GY+ +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVT 478
Query: 1111 CMDIDECQRDPLLCRGG-----VCHNTEGSYRCECP-PGHQLSPNISACIDINECELSAH 1164
C DIDEC L GG C N GS++C CP G++L+PN C DI+EC H
Sbjct: 479 CEDIDEC----ALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIH 534
Query: 1165 LCP-NGRCVNLIGKYQC 1180
C N C N+ G ++C
Sbjct: 535 NCSINETCFNIQGGFRC 551
Score = 155 bits (391), Expect = 7e-37
Identities = 141/458 (30%), Positives = 183/458 (39%), Gaps = 100/458 (21%)
Query: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYT--GDGFTCTDLDECSENLNLCGNGQ-CL 1421
D C G C Q C++T C C GY DG +C D++EC + C G+ C+
Sbjct: 178 DRCRGGGP-CKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 1422 NAPGGYRCE----CDMGFVPSADGKACEDIDECS--LPNICVFGTCHNLPGLFRC----E 1471
N G +RC+ C G+ + D +C+DIDEC + N C N G FRC +
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDN-SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 1472 CEIGYELDRSGGNCTDVNECLDPTT-CISGN-CVNTPGSYIC-----DCPPDFELNPTRV 1524
C+ G+ D G NC D+NECL + C G+ C+NT GSY C +C + LN
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 1525 GCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSE 1584
CVD C P G C N G C C G + MC
Sbjct: 353 RCVDV--DECAPPAEPCGKGH--RCVNSPG----SFRCECKTGYYFDGISRMCV------ 398
Query: 1585 YKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTR 1644
D++ECQ PG G KC NT GS+ C C G+ L+ D R
Sbjct: 399 ---------------------DVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGR 437
Query: 1645 VCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQ 1704
C+D+NEC + C C N G+Y C C RR Y+ D
Sbjct: 438 SCEDINECSS-SPCSQ-ECANVYGSYQCYC----------------RRG--YQLSDVDGV 477
Query: 1705 TCDGELLFNMTKKMCCCSYNIGRAWNKPCE-QCPIPSTDEFATLCGSQRPGFVIDIYTGL 1763
TC+ + CSY R N P QC PS+ G+ +
Sbjct: 478 TCEDIDECALPTGGHICSY---RCINIPGSFQCSCPSS------------GYRLAPNGRN 522
Query: 1764 PVDIDEC-REIPGVCENGVCINMVGSFRC---ECPVGF 1797
DIDEC I N C N+ G FRC ECP +
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 154 bits (390), Expect = 9e-37
Identities = 122/391 (31%), Positives = 164/391 (41%), Gaps = 87/391 (22%)
Query: 243 ACQDVDECQAIPGLCQ-GGNCINTVGSFECK----CPAGHKLNEVSQKCEDIDEC-STIP 296
+C+DV+EC C+ G +CINTVGSF C+ C G++L E C+DIDEC S I
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTE-DNSCKDIDECESGIH 271
Query: 297 GICEGGECTNTVSSYFCK----CPPGFYTS------------------PDGTRCIDVRPG 334
C NT+ S+ C+ C GF P G CI+
Sbjct: 272 NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGS 331
Query: 335 Y-CYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPM 393
Y C + N L + T+ C D C P + + F C
Sbjct: 332 YTCQKNVPNCGRGYHLNEEGTR---CVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388
Query: 394 VIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYC 453
G + R V+ R P R
Sbjct: 389 YFDG-----------------------------ISRMCVDVNECQRYPGR---------- 409
Query: 454 QLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECEKNPCAGGECINNQGSYT 512
LC + +C T GS C C+ GF+L + G C D++EC +PC+ EC N GSY
Sbjct: 410 -----LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQ-ECANVYGSYQ 462
Query: 513 CQCRAGYQ-STLTRTECRDIDECL--QNGRICNNGRCINTDGSFHCVC-NAGFHVTRDGK 568
C CR GYQ S + C DIDEC G IC+ RCIN GSF C C ++G+ + +G+
Sbjct: 463 CYCRRGYQLSDVDGVTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPNGR 521
Query: 569 NCEDMDEC--SIRNMCLNGMCINEDGSFKCI 597
NC+D+DEC I N +N C N G F+C+
Sbjct: 522 NCQDIDECVTGIHNCSINETCFNIQGGFRCL 552
Score = 149 bits (377), Expect = 3e-35
Identities = 84/217 (38%), Positives = 124/217 (57%), Gaps = 18/217 (8%)
Query: 453 CQLVRYLCQNGR-CIPTPGSCRCE-----CNKGFQLDLRG-ECIDVDECEK--NPCAGGE 503
C + C G CI T GS C+ C +G+ L+ G C+DVDEC PC G
Sbjct: 312 CLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH 371
Query: 504 -CINNQGSYTCQCRAGYQSTLTRTECRDIDECLQN-GRICNNGRCINTDGSFHCVCNAGF 561
C+N+ GS+ C+C+ GY C D++EC + GR+C + +C NT GS+ C C+ GF
Sbjct: 372 RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGF 430
Query: 562 HVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLAS-DGRYCKDINECETP 620
++ DG++CED++ECS + + C N GS++C C+ G+QL+ DG C+DI+EC P
Sbjct: 431 RLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALP 488
Query: 621 --GICMNGRCVNTDGSYRCEC-FPGLAVGLDGRVCVD 654
G + RC+N GS++C C G + +GR C D
Sbjct: 489 TGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQD 525
Score = 136 bits (343), Expect = 3e-31
Identities = 124/427 (29%), Positives = 176/427 (41%), Gaps = 94/427 (22%)
Query: 1470 CECEIGYELDRSGGNCTDVNECLDPT-TCISG-NCVNTPGSYICD----CPPDFELNPTR 1523
C C +GY+L G +C DVNEC+ + +C G +C+NT GS+ C C +EL
Sbjct: 199 CSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYEL---- 254
Query: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS 1583
T +C DI C + I + C +LG P C +
Sbjct: 255 -----TEDNSCK-DI--------DECESGIHNCLPDFICQNTLGSFRCRPKLQCKS---- 296
Query: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCR-----CPTGY 1637
GF + + + DI+EC + C G CINT GS+ C+ C GY
Sbjct: 297 ----------GFIQDALGNCI-DINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 1638 YLNEDTRVCDDVNECETPGI-CGPG-TCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLC 1695
+LNE+ C DV+EC P CG G C N+ G++ C C Y C+D+
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 1696 YRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGF 1755
Y + C + + +C CS GF
Sbjct: 406 Y-----PGRLCGHKCENTLGSYLCSCSV------------------------------GF 430
Query: 1756 VIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYND-KLLVCEDIDEC-- 1812
+ + DI+EC P E C N+ GS++C C G+ +D + CEDIDEC
Sbjct: 431 RLSVDGRSCEDINECSSSPCSQE---CANVYGSYQCYCRRGYQLSDVDGVTCEDIDECAL 487
Query: 1813 -QNGPVCQRNAECINTAGSYRCDC-KPGYRFTSTGQ-CNDRNECQEIPNICSHGQ-CIDT 1868
G +C + CIN GS++C C GYR G+ C D +EC + CS + C +
Sbjct: 488 PTGGHIC--SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNI 545
Query: 1869 VGSFYCL 1875
G F CL
Sbjct: 546 QGGFRCL 552
Score = 103 bits (258), Expect = 2e-21
Identities = 85/302 (28%), Positives = 112/302 (37%), Gaps = 64/302 (21%)
Query: 118 HCNIRCMNGGSCSDDH--------CLCQKGYI----GTHC--------GQPVCESG--CL 155
+ N RC GG C C C GY G C G C G C+
Sbjct: 175 YLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 156 N---GGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQM----CQGQLSGIVCTKTL 208
N RC + C Y T +D C + I N + CQ L C L
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDI--DECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 209 CCAT--VGRAWGH------------PCEM------------CPAQPHPCRRGFIPNIRTG 242
C + + A G+ PC + C C RG+ N
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 243 ACQDVDECQAIPGLC-QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG 301
C DVDEC C +G C+N+ GSF C+C G+ + +S+ C D++EC PG G
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 302 GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCD 361
+C NT+ SY C C GF S DG C D+ ++ CS + QC C
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCEDI------NECSSSPCSQECANVYGSYQCYCR 466
Query: 362 AG 363
G
Sbjct: 467 RG 468
Score = 89.4 bits (220), Expect = 5e-17
Identities = 86/284 (30%), Positives = 125/284 (44%), Gaps = 51/284 (17%)
Query: 84 ICRHSCGDGFCSRPNMCTCPSGQIAPSCGSR-SIQHC---NIRCMNGGSC--SDDHCLCQ 137
IC+++ G C RP + C SG I + G+ I C + C G +C ++ CQ
Sbjct: 278 ICQNTLGSFRC-RPKL-QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQ 335
Query: 138 KGYIGTHCGQPVCESG--CLNGGRCVAP-------NRCACTYGFTGPQCERDYRTGPCFT 188
K G + E G C++ C P +RC + G +C +TG F
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC----KTGYYFD 391
Query: 189 VISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCE------MCPAQPHPCRRGFIPNIRTG 242
IS +MC C GR GH CE +C C GF ++
Sbjct: 392 GIS-RMC--------VDVNECQRYPGRLCGHKCENTLGSYLCS-----CSVGFRLSVDGR 437
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEV-SQKCEDIDECSTIPG--IC 299
+C+D++EC + P C C N GS++C C G++L++V CEDIDEC+ G IC
Sbjct: 438 SCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC 494
Query: 300 EGGECTNTVSSYFCKCP-PGFYTSPDGTRCIDVRPGYCYTALTN 342
C N S+ C CP G+ +P+G C D+ C T + N
Sbjct: 495 -SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI--DECVTGIHN 535
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 244 bits (624), Expect = 7e-64
Identities = 176/545 (32%), Positives = 245/545 (44%), Gaps = 91/545 (16%)
Query: 1005 EELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSE 1064
E C G AT + P+ + EC+M+ C H + + C +G +L +E
Sbjct: 34 EACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLE------ELHCATGISLANE 87
Query: 1065 ERNC------------TDIDECRISPDLCGRGQCVNTPG-DFECKCDEGYESGFMMMKNC 1111
+ C T + C C G+ G E GY+ G + C
Sbjct: 88 QDRCATPHGDNASLEATFVKRC---CHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACC 144
Query: 1112 --------------------MDIDECQRDPLL---CRGG-----VCHNTEGSYRCECPPG 1143
++++E Q DP L CRGG C +T C C G
Sbjct: 145 VKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVG 204
Query: 1144 HQLSPNISACIDINECELSAHLCPNGR-CVNLIGKYQC----ACNPGYHSTPDRLFCVDI 1198
+QL + +C D+NEC +H C G C+N +G ++C +C GY T D C DI
Sbjct: 205 YQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDN-SCKDI 263
Query: 1199 DECSIMNGGC--ETFCTNSEGSYEC----SCQPGFALMPDQRSCTDIDECEDNPNICD-G 1251
DEC C + C N+ GS+ C C+ GF + +C DI+EC C G
Sbjct: 264 DECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF-IQDALGNCIDINECLSISAPCPIG 322
Query: 1252 GQCTNIPGEYRCL-----CYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFIC 1305
C N G Y C C G+ +E+ CVDV+EC C G C N+ GSF C
Sbjct: 323 HTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRC 382
Query: 1306 HCDMGYSGKKGKTGCTDINECE-IGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIKCT 1362
C GY C D+NEC+ CG C NT GS+ CSCS G+ DG C
Sbjct: 383 ECKTGYYFDGISRMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCE 440
Query: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY---TGDGFTCTDLDECS--ENLNLCGN 1417
D++ECS+ CSQ +C N GSY+C C+ GY DG TC D+DEC+ ++C +
Sbjct: 441 DINECSSSP--CSQ--ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC-S 495
Query: 1418 GQCLNAPGGYRCEC-DMGFVPSADGKACEDIDEC--SLPNICVFGTCHNLPGLFRC---E 1471
+C+N PG ++C C G+ + +G+ C+DIDEC + N + TC N+ G FRC E
Sbjct: 496 YRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFE 555
Query: 1472 CEIGY 1476
C Y
Sbjct: 556 CPENY 560
Score = 228 bits (581), Expect = 7e-59
Identities = 144/402 (35%), Positives = 200/402 (49%), Gaps = 45/402 (11%)
Query: 1085 QCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCE---- 1139
QC +T + C C GY+ +C D++EC CR G C NT GS+RC+
Sbjct: 189 QCRDTGDEVVCSCFVGYQL-LSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSS 247
Query: 1140 CPPGHQLSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCA----CNPGYHSTPDRLF 1194
C G++L+ + ++C DI+ECE H C P+ C N +G ++C C G+ D L
Sbjct: 248 CGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF--IQDALG 304
Query: 1195 -CVDIDECSIMNGGCET--FCTNSEGSYEC-----SCQPGFALMPDQRSCTDIDECEDNP 1246
C+DI+EC ++ C C N+EGSY C +C G+ L + C D+DEC
Sbjct: 305 NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPA 364
Query: 1247 NICDGG-QCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFIC 1305
C G +C N PG +RC C G+ + CVDVNEC P CENT GS++C
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLC 424
Query: 1306 HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW---IGDGIKCT 1362
C +G+ C DINEC + C + C N GS++C C G+ DG+ C
Sbjct: 425 SCSVGFRLSVDGRSCEDINEC--SSSPCSQE--CANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 1363 DLDECS--NGTHMCSQHADCKNTMGSYRCLC-KEGY--TGDGFTCTDLDECSENLNLCG- 1416
D+DEC+ G H+CS C N GS++C C GY +G C D+DEC ++ C
Sbjct: 481 DIDECALPTGGHICSYR--CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 1417 NGQCLNAPGGYRC---ECDMGFVPSADGKA----CEDIDECS 1451
N C N GG+RC EC + SA + C + ECS
Sbjct: 539 NETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECS 580
Score = 218 bits (556), Expect = 5e-56
Identities = 184/631 (29%), Positives = 253/631 (40%), Gaps = 120/631 (19%)
Query: 1121 PLLCRGGVCHNTEGS-----YRCECPPGHQLSPNISAC-----IDINECELSAHLCPNGR 1170
PLL GG+ G C GH+++ + C + EC + C
Sbjct: 13 PLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQC---- 68
Query: 1171 CVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALM 1230
C + + + CA + DR D S+ + C C C G A
Sbjct: 69 CHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCC-------HC-CLLGRAAQ 120
Query: 1231 PDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASE-------DMKTCVDVNE 1283
+SC ++ G QC + +R C + + ++V E
Sbjct: 121 AQGQSC--------EYSLMVGYQCGQV---FRACCVKSQETGDLDVGGLQETDKIIEVEE 169
Query: 1284 CDLNPNI---CLSG-----TCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK 1335
+P + C G C +T +C C +GY C D+NEC G+H+C
Sbjct: 170 EQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRL 229
Query: 1336 HAVCTNTAGSFKC----SCSPGW-IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL 1390
C NT GSF+C SC G+ + + C D+DEC +G H C C+NT+GS+RC
Sbjct: 230 GESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCR 289
Query: 1391 ----CKEGYTGDGF-TCTDLDECSENLNLCGNGQ-CLNAPGGYRCE-----CDMGFVPSA 1439
CK G+ D C D++EC C G C+N G Y C+ C G+ +
Sbjct: 290 PKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNE 349
Query: 1440 DGKACEDIDECSLP-NICVFG-TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLD-PTT 1496
+G C D+DEC+ P C G C N PG FRCEC+ GY D C DVNEC P
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
C NT GSY+C C F L+ C D + + CS E
Sbjct: 410 LCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN------------ECSSSPCSQECANV 457
Query: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPG- 1615
C C G Y++ G V EDIDEC G
Sbjct: 458 YGSYQCYCRRG-----------------YQLSDVDG---------VTCEDIDECALPTGG 491
Query: 1616 -LCQGGKCINTFGSFQCRCP-TGYYLNEDTRVCDDVNECETPGI--CGPG-TCYNTVGNY 1670
+C +CIN GSFQC CP +GY L + R C D++EC T GI C TC+N G +
Sbjct: 492 HICSY-RCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVT-GIHNCSINETCFNIQGGF 549
Query: 1671 TCI---CPPDYMQVNGGNNCMDMRRSLCYRN 1698
C+ CP +Y + + C R C+ N
Sbjct: 550 RCLAFECPENYRR-SAATRC---ERLPCHEN 576
Score = 214 bits (544), Expect = 1e-54
Identities = 167/535 (31%), Positives = 236/535 (44%), Gaps = 74/535 (13%)
Query: 1109 KNCMDIDE----CQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAH 1164
K C + E Q + L C G+ E RC P G +A ++ + H
Sbjct: 59 KECRMVQEQCCHSQLEELHCATGISLANEQD-RCATPHGD------NASLEATFVKRCCH 111
Query: 1165 LCPNGRCVNLIGK---------YQC-----AC----------NPGYHSTPDRLFCVDID- 1199
C GR G+ YQC AC + G D++ V+ +
Sbjct: 112 CCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ 171
Query: 1200 ECSIMN------GGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD-GG 1252
E +N G C+ C ++ CSC G+ L+ D SC D++EC + C G
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGE 231
Query: 1253 QCTNIPGEYRC----LCYDGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFIC-- 1305
C N G +RC C G+ +ED +C D++EC+ + CL C+NT GSF C
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRP 290
Query: 1306 --HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-----SCSPGW--IG 1356
C G+ + C DINEC + C C NT GS+ C +C G+
Sbjct: 291 KLQCKSGFI-QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNE 349
Query: 1357 DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFT--CTDLDECSENL-N 1413
+G +C D+DEC+ C + C N+ GS+RC CK GY DG + C D++EC
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECE 1473
LCG+ +C N G Y C C +GF S DG++CEDI+ECS + C N+ G ++C C
Sbjct: 410 LCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQECANVYGSYQCYCR 466
Query: 1474 IGYEL-DRSGGNCTDVNECLDPT--TCISGNCVNTPGSYICDCPPD-FELNPTRVGCVDT 1529
GY+L D G C D++EC PT S C+N PGS+ C CP + L P C D
Sbjct: 467 RGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI 526
Query: 1530 RSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSE 1584
C I N +T + + G C + ++ T CE P E
Sbjct: 527 --DECVTGIHNCSIN-ETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRE 578
Score = 210 bits (534), Expect = 2e-53
Identities = 146/414 (35%), Positives = 190/414 (45%), Gaps = 56/414 (13%)
Query: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
G C+ +C +T C C G+ + C D E C T + C++G S N V
Sbjct: 184 GPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNE--CITG--SHSCRLGESCINTVG 238
Query: 2360 KSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKV-IHDVCRNGEC 2418
C D G G + C DIDEC+ IH+ + C
Sbjct: 239 SFRCQRDSSCGTGYE---------LTEDNSCK----------DIDECESGIHNCLPDFIC 279
Query: 2419 VNDRGSYHCI----CKTGYTPDITGTSCVDLNECNQ--APKPCNFICKNTEGSYQC---- 2468
N GS+ C CK+G+ D G +C+D+NEC AP P C NTEGSY C
Sbjct: 280 QNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNV 338
Query: 2469 -SCPKGYILQEDGRSCKDLDECATKQHNCQ--FLCVNTIGGFTCKCPPGFTQHHTS--CI 2523
+C +GY L E+G C D+DECA C CVN+ G F C+C G+ S C+
Sbjct: 339 PNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCV 398
Query: 2524 DNNECTS-DINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQ 2582
D NEC LCG K C+NT GS+ C C GF L G SCED++EC + C C
Sbjct: 399 DVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP-CSQECA 455
Query: 2583 NIIGGYRCSCPQGY-LQHYQWNQCVDENECL---SAHICGGASCHNTLGSYKCMCPA-GF 2637
N+ G Y+C C +GY L C D +EC HIC C N GS++C CP+ G+
Sbjct: 456 NVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICS-YRCINIPGSFQCSCPSSGY 514
Query: 2638 QYEQFSGGCQDINECGSAQAPCSYG--CSNTEGGYLC---GCPPGYFRIGQGHC 2686
+ CQDI+EC + CS C N +GG+ C CP Y R C
Sbjct: 515 RLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRC 568
Score = 209 bits (533), Expect = 2e-53
Identities = 140/436 (32%), Positives = 193/436 (44%), Gaps = 60/436 (13%)
Query: 2168 DECSVGNPCGNGTCKNVIGGFECTCEEGFEP-GPMMTCEDINECAQNPLLCAF--RCVNT 2224
D C G PC C++ C+C G++ ++CED+NEC C C+NT
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2225 YGSYECK----CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI----C 2276
GS+ C+ C GY L ED CKD DECE G H+C + C+N +G++ C C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFI-CQNTLGSFRCRPKLQC 294
Query: 2277 GPGYQRRPDGEGCVDENECQTKPGICENGR-CLNTRGSYTCE-----CNDGFTASPNQDE 2330
G+ + G C+D NEC + C G C+NT GSYTC+ C G+ +
Sbjct: 295 KSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 2331 CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLC 2390
C+D E C C G N C C G + +C
Sbjct: 354 CVDVDE--CAPPA--EPCGKGHRCVNSPGSFRCECKTGYYFDGISRMC------------ 397
Query: 2391 PHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQ 2450
D++EC+ +C N GSY C C G+ + G SC D+NEC+
Sbjct: 398 ----------VDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 2451 APKPCNFICKNTEGSYQCSCPKGYILQE-DGRSCKDLDECA--TKQHNCQFLCVNTIGGF 2507
+P C+ C N GSYQC C +GY L + DG +C+D+DECA T H C + C+N G F
Sbjct: 448 SP--CSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSF 505
Query: 2508 TCKCPPG---FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC---ECQRGFSLDQT 2561
C CP + +C D +EC + I+ C C N G F C EC +
Sbjct: 506 QCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYR-RSA 564
Query: 2562 GSSCEDVDECEGNHRC 2577
+ CE + C N C
Sbjct: 565 ATRCERL-PCHENREC 579
Score = 199 bits (507), Expect = 3e-50
Identities = 178/621 (28%), Positives = 250/621 (40%), Gaps = 126/621 (20%)
Query: 1958 CNEGYEVAPDGRTC-----VDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE 2012
C +G+ +A + C + EC + +C + L C G SL NE+
Sbjct: 37 CADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELH------CATGISLANEQ-- 88
Query: 2013 DIDECVEEPEICALGTCSNTEGSF--KCL--CPEGFSLSSSGRRCQDLRMSYCYAKFEGG 2068
D C G ++ E +F +C C G + + G+ C+ Y+ G
Sbjct: 89 --DRCATPH-----GDNASLEATFVKRCCHCCLLGRAAQAQGQSCE-------YSLMVGY 134
Query: 2069 KCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDM 2128
+C C +K + GD E D+ + +
Sbjct: 135 QCGQVFR--------ACCVKSQETGDLDVGGLQETDKIIE---------VEEEQEDPYLN 177
Query: 2129 DECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTDECSVGN-PCGNG-TCKNV 2184
D C+ CK QC +T C C GY L G C D +EC G+ C G +C N
Sbjct: 178 DRCRGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINT 236
Query: 2185 IGGFEC----TCEEGFEPGPMMTCEDINECAQNPLLCA--FRCVNTYGSYECK----CPV 2234
+G F C +C G+E +C+DI+EC C F C NT GS+ C+ C
Sbjct: 237 VGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKS 296
Query: 2235 GYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI-----CGPGYQRRPDGEGC 2289
G++ ++ C D +EC C C N G+Y C CG GY +G C
Sbjct: 297 GFI-QDALGNCIDINECLSISAPCPIGHT-CINTEGSYTCQKNVPNCGRGYHLNEEGTRC 354
Query: 2290 VDENECQTKPGICENG-RCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMC 2348
VD +EC C G RC+N+ GS+ CEC G+ + + + MC
Sbjct: 355 VDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY-----------------YFDGISRMC 397
Query: 2349 QIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG-----ADI 2403
V +EC GR G CE LC GF + DI
Sbjct: 398 ---------VDVNECQRYPGRLCGHKCE------NTLGSYLCSCSVGFRLSVDGRSCEDI 442
Query: 2404 DECKVIHDVCRNGECVNDRGSYHCICKTGYT-PDITGTSCVDLNECN--QAPKPCNFICK 2460
+EC C EC N GSY C C+ GY D+ G +C D++EC C++ C
Sbjct: 443 NECS--SSPCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCI 499
Query: 2461 NTEGSYQCSCPK-GYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTC---KCPPG 2514
N GS+QCSCP GY L +GR+C+D+DEC T HNC C N GGF C +CP
Sbjct: 500 NIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPEN 559
Query: 2515 FTQ------HHTSCIDNNECT 2529
+ + C +N EC+
Sbjct: 560 YRRSAATRCERLPCHENRECS 580
Score = 199 bits (505), Expect = 4e-50
Identities = 148/514 (28%), Positives = 225/514 (43%), Gaps = 70/514 (13%)
Query: 2349 QIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA---DIDE 2405
++ +P C RG GP + C G C G +++G D++E
Sbjct: 166 EVEEEQEDPYLNDRC-----RGGGPCKQQCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNE 219
Query: 2406 CKVIHDVCRNGE-CVNDRGSYHC----ICKTGYTPDIT-GTSCVDLNECNQAPKPC--NF 2457
C CR GE C+N GS+ C C TGY ++T SC D++EC C +F
Sbjct: 220 CITGSHSCRLGESCINTVGSFRCQRDSSCGTGY--ELTEDNSCKDIDECESGIHNCLPDF 277
Query: 2458 ICKNTEGSYQC----SCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCK- 2510
IC+NT GS++C C G+I G +C D++EC + C C+NT G +TC+
Sbjct: 278 ICQNTLGSFRCRPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQK 336
Query: 2511 ----CPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSS 2564
C G+ + T C+D +EC CG C N+PGSF CEC+ G+ D
Sbjct: 337 NVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRM 396
Query: 2565 CEDVDECE--GNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASC 2622
C DV+EC+ C H C+N +G Y CSC G+ C D NEC S+ C
Sbjct: 397 CVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC--SQEC 454
Query: 2623 HNTLGSYKCMCPAGFQYEQFSG-GCQDINECG--SAQAPCSYGCSNTEGGYLCGCPPGYF 2679
N GSY+C C G+Q G C+DI+EC + CSY C N G + C CP +
Sbjct: 455 ANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGY 514
Query: 2680 RIGQG--------HCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKRR 2731
R+ CV+G+ + +++ + + + C P+ R+
Sbjct: 515 RLAPNGRNCQDIDECVTGIH----------NCSINETCFNIQGGFRCLAFECPENYRRSA 564
Query: 2732 STNETDASNIEDQSETEANVSLASWDVEKTAIFAFNISHVSNKVRILELLPALTTLTNHN 2791
+T E++ ++ + + + + F NI + + P+ +
Sbjct: 565 ATRCERLPCHENRECSKLPLRITYYHLS----FPTNI---QAPAVVFRMGPSSAVPGDSM 617
Query: 2792 RYLIESGNEDGFF---KINQKEGISYLHFTKKKP 2822
+ I GNE+GFF K++ G+ L TK P
Sbjct: 618 QLAITGGNEEGFFTTRKVSPHSGVVAL--TKPVP 649
Score = 194 bits (492), Expect = 1e-48
Identities = 151/487 (31%), Positives = 213/487 (43%), Gaps = 79/487 (16%)
Query: 1717 KMCCCSYNIGRAWNKPCEQCPIPST------DEFATLCGSQRPGFVIDI----YTGLPVD 1766
K CC +GRA + C F C + +D+ T ++
Sbjct: 107 KRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIE 166
Query: 1767 IDECREIPGV---CENG-----VCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGP-V 1817
++E +E P + C G C + C C VG+ + CED++EC G
Sbjct: 167 VEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHS 226
Query: 1818 CQRNAECINTAGSYRCD----CKPGYRFTSTGQCNDRNECQE-IPNICSHGQCIDTVGSF 1872
C+ CINT GS+RC C GY T C D +EC+ I N C +T+GSF
Sbjct: 227 CRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSF 286
Query: 1873 YCL----CHTGFKTNDDQTMCLDINECERDA--CGNG-TCRNTIGSFNCR-----CNHGF 1920
C C +GF D C+DINEC + C G TC NT GS+ C+ C G+
Sbjct: 287 RCRPKLQCKSGF-IQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 1921 ILSHNND-CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLL 1979
L+ C+DVDECA + +C+N+ GSF+C+C GY R CVD+NEC
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 1980 EPRKCAPGTCQNLDGSYRCICPPGY--SLQNEKCEDIDECVEEPEICALGTCSNTEGSFK 2037
P + C+N GSY C C G+ S+ CEDI+EC P C+ C+N GS++
Sbjct: 406 YPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--CS-QECANVYGSYQ 462
Query: 2038 CLCPEGFSLSS-SGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPC 2096
C C G+ LS G C+D+ +C+ P + H C + G
Sbjct: 463 CYCRRGYQLSDVDGVTCEDI-----------DECALP-TGGHICSYRCINIPG------- 503
Query: 2097 ELCPTEPDEAFRQICPYGSGIIVGPDD-SAVDMDECKE--PDVCKHGQCINTDGSYRC-- 2151
+F+ CP SG + P+ + D+DEC + + C N G +RC
Sbjct: 504 ---------SFQCSCP-SSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLA 553
Query: 2152 -ECPFGY 2157
ECP Y
Sbjct: 554 FECPENY 560
Score = 180 bits (456), Expect = 2e-44
Identities = 156/515 (30%), Positives = 218/515 (42%), Gaps = 105/515 (20%)
Query: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRG-----ECIDVDECEKNP-----CA 500
+Y +V Y C G+ +C + + LD+ G + I+V+E +++P C
Sbjct: 127 EYSLMVGYQC--GQVFR---ACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCR 181
Query: 501 GG-----ECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGR-CINTDGSFH 554
GG +C + C C GYQ C D++EC+ C G CINT GSF
Sbjct: 182 GGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFR 241
Query: 555 C----VCNAGFHVTRDGKNCEDMDEC--SIRNMCLNGMCINEDGSFKC----ICKPGFQL 604
C C G+ +T D +C+D+DEC I N + +C N GSF+C CK GF
Sbjct: 242 CQRDSSCGTGYELTED-NSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQ 300
Query: 605 ASDGRYCKDINEC-ETPGICMNGR-CVNTDGSYRCE-----CFPGLAVGLDGRVCVDTHM 657
+ G C DINEC C G C+NT+GSY C+ C G + +G CVD
Sbjct: 301 DALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV-- 357
Query: 658 RSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG--- 714
EC + G C P ++ C +G
Sbjct: 358 -----------------------DECAPPAEPCGKGHRCVNSP----GSFRCECKTGYYF 390
Query: 715 PGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSL 774
G++ D+NEC P CEN G+Y C C+ G+ + G++C DINEC +S
Sbjct: 391 DGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC--SSS 448
Query: 775 LCDNGQCRNTPGSFVCTCPKGF-IYKPDLKTCEDIDECESSPCINGVCK----NSPGSFI 829
C +C N GS+ C C +G+ + D TCEDIDEC + P +C N PGSF
Sbjct: 449 PCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDEC-ALPTGGHICSYRCINIPGSFQ 506
Query: 830 CEC-SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCT 888
C C SS L P C + ID C I+ ++ C + G G C
Sbjct: 507 CSCPSSGYRLAPNGRNCQD----------ID-ECVTGIHNCSINETCFNIQG---GFRCL 552
Query: 889 LCQVDPICGKGYSRIKGTQCEDID-----ECEVFP 918
+ C + Y R T+CE + EC P
Sbjct: 553 AFE----CPENYRRSAATRCERLPCHENRECSKLP 583
Score = 169 bits (429), Expect = 3e-41
Identities = 144/466 (30%), Positives = 189/466 (40%), Gaps = 117/466 (25%)
Query: 780 QCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLD 839
QCR+T VC+C G+ D +CED++EC + GS C
Sbjct: 189 QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECIT------------GSHSCR-------- 228
Query: 840 PTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKG 899
L C +++G+ CQ D CG G
Sbjct: 229 -------------------------------LGESCINTVGSF------RCQRDSSCGTG 251
Query: 900 YSRIKGTQCEDIDECEVFPGVC-KNGLCVNTRGSFKC----QCPSGMTLDATGRICLDIR 954
Y + C+DIDECE C + +C NT GSF+C QC SG DA G C+DI
Sbjct: 252 YELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDIN 310
Query: 955 L-----------ETCFLRYEDEEC--TLPIAGR----HRMDACCCSVGAAWGTEECEECP 997
TC C +P GR + C V +EC P
Sbjct: 311 ECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDV------DEC--AP 362
Query: 998 MRNTPEYEELCPRGPGFATKEITNGKPF------FKDINECKMIPS-LCTHGKCRNTIGS 1050
C PG E G F D+NEC+ P LC H KC NT+GS
Sbjct: 363 PAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KCENTLGS 421
Query: 1051 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKN 1110
+ C C GF L + R+C DI+EC SP C + +C N G ++C C GY+ +
Sbjct: 422 YLCSCSVGFRLSVDGRSCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVT 478
Query: 1111 CMDIDECQRDPLLCRGG-----VCHNTEGSYRCECP-PGHQLSPNISACIDINECELSAH 1164
C DIDEC L GG C N GS++C CP G++L+PN C DI+EC H
Sbjct: 479 CEDIDEC----ALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIH 534
Query: 1165 LCP-NGRCVNLIGKYQC---ACNPGYHSTP----DRLFCVDIDECS 1202
C N C N+ G ++C C Y + +RL C + ECS
Sbjct: 535 NCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECS 580
Score = 167 bits (424), Expect = 1e-40
Identities = 137/440 (31%), Positives = 190/440 (43%), Gaps = 73/440 (16%)
Query: 532 DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC--SIRNMCLNGMCIN 589
D C + G C +C +T C C G+ + DG +CED++EC + L CIN
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 590 EDGSFKC----ICKPGFQLASDGRYCKDINECETPGI--CM-NGRCVNTDGSYRCECFPG 642
GSF+C C G++L D CKDI+ECE+ GI C+ + C NT GS+RC
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNS-CKDIDECES-GIHNCLPDFICQNTLGSFRCR---- 289
Query: 643 LAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQ 702
+ C G+ + L + +EC S G C
Sbjct: 290 --------------PKLQCKSGFIQDA----LGNCIDINECLSISAPCPIGHTCINTEGS 331
Query: 703 NSAEYQAL-CSSGPGMTSAGS---DINECALDPDICPNGI-CENLRGTYKCICNSGYEVD 757
+ + C G + G+ D++ECA + C G C N G+++C C +GY D
Sbjct: 332 YTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFD 391
Query: 758 STGKNCVDINECV-LNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPC 816
+ CVD+NEC LC + +C NT GS++C+C GF D ++CEDI+EC SSPC
Sbjct: 392 GISRMCVDVNECQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC 450
Query: 817 INGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQT---VIDGRCEININGATLKS 873
+ C N GS+ C C L + E I T + RC INI G + +
Sbjct: 451 -SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRC-INIPG-SFQC 507
Query: 874 QCCSSLGAAWGSPCTLCQVDPICGKGYSRI-KGTQCEDIDECEVFPGVCK-NGLCVNTRG 931
C SS GY G C+DIDEC C N C N +G
Sbjct: 508 SCPSS--------------------GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQG 547
Query: 932 SFKC---QCPSGMTLDATGR 948
F+C +CP A R
Sbjct: 548 GFRCLAFECPENYRRSAATR 567
Score = 103 bits (258), Expect = 2e-21
Identities = 85/302 (28%), Positives = 112/302 (37%), Gaps = 64/302 (21%)
Query: 118 HCNIRCMNGGSCSDDH--------CLCQKGYI----GTHC--------GQPVCESG--CL 155
+ N RC GG C C C GY G C G C G C+
Sbjct: 175 YLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCI 234
Query: 156 N---GGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQM----CQGQLSGIVCTKTL 208
N RC + C Y T +D C + I N + CQ L C L
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNSCKDI--DECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 209 CCAT--VGRAWGH------------PCEM------------CPAQPHPCRRGFIPNIRTG 242
C + + A G+ PC + C C RG+ N
Sbjct: 293 QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 243 ACQDVDECQAIPGLC-QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG 301
C DVDEC C +G C+N+ GSF C+C G+ + +S+ C D++EC PG G
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG 412
Query: 302 GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCD 361
+C NT+ SY C C GF S DG C D+ ++ CS + QC C
Sbjct: 413 HKCENTLGSYLCSCSVGFRLSVDGRSCEDI------NECSSSPCSQECANVYGSYQCYCR 466
Query: 362 AG 363
G
Sbjct: 467 RG 468
Score = 89.4 bits (220), Expect = 5e-17
Identities = 86/284 (30%), Positives = 125/284 (44%), Gaps = 51/284 (17%)
Query: 84 ICRHSCGDGFCSRPNMCTCPSGQIAPSCGSR-SIQHC---NIRCMNGGSC--SDDHCLCQ 137
IC+++ G C RP + C SG I + G+ I C + C G +C ++ CQ
Sbjct: 278 ICQNTLGSFRC-RPKL-QCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQ 335
Query: 138 KGYIGTHCGQPVCESG--CLNGGRCVAP-------NRCACTYGFTGPQCERDYRTGPCFT 188
K G + E G C++ C P +RC + G +C +TG F
Sbjct: 336 KNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC----KTGYYFD 391
Query: 189 VISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCE------MCPAQPHPCRRGFIPNIRTG 242
IS +MC C GR GH CE +C C GF ++
Sbjct: 392 GIS-RMC--------VDVNECQRYPGRLCGHKCENTLGSYLCS-----CSVGFRLSVDGR 437
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEV-SQKCEDIDECSTIPG--IC 299
+C+D++EC + P C C N GS++C C G++L++V CEDIDEC+ G IC
Sbjct: 438 SCEDINECSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHIC 494
Query: 300 EGGECTNTVSSYFCKCP-PGFYTSPDGTRCIDVRPGYCYTALTN 342
C N S+ C CP G+ +P+G C D+ C T + N
Sbjct: 495 -SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDI--DECVTGIHN 535
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 242 bits (617), Expect = 4e-63
Identities = 162/480 (33%), Positives = 219/480 (45%), Gaps = 61/480 (12%)
Query: 1754 GFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ 1813
GF +D D DEC C + C N +G++ C CP G C+DIDEC
Sbjct: 5095 GFTLDSVGPFCADEDECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECA 5152
Query: 1814 NGP-VCQRNAECINTAGSYRC--DCKPGYRFTSTG-QCNDRNECQEIPNICSHGQCIDTV 1869
G C +C NT GSYRC C G+R TS G C D NECQE + H +C + +
Sbjct: 5153 LGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE--SSPCHQRCFNAI 5210
Query: 1870 GSFYCLCHTGFKTNDDQTMCLDINECERDACG-NGTCRNTIGSFNC--RCNHGFILSHNN 1926
GSF+C C G++ + C+D+NEC ++ C + C+NT G + C C +G + N
Sbjct: 5211 GSFHCGCEPGYQLKGRK--CMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG 5268
Query: 1927 DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP 1986
CID+DEC G N C NT GS++C C GY GR C+DINEC P+ CA
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCA- 5327
Query: 1987 GTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSL 2046
C N GS++CICPPG L D C + GT + + P +
Sbjct: 5328 HQCSNTPGSFKCICPPGQHLLG----DGKSCAGLERLPNYGT-QYSSYNLARFSPVRNNY 5382
Query: 2047 SSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEA 2106
Q + Y+++ + S ++R
Sbjct: 5383 QPQQHYRQYSHLYSSYSEYRNSRTSLSRTR----------------------------RT 5414
Query: 2107 FRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNEC 2164
R+ CP GS D+ VD+DEC+ D C+H +C NT GSY+C CP GY L G C
Sbjct: 5415 IRKTCPEGS---EASHDTCVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTC 5470
Query: 2165 VDTDECSVGN-PCG-NGTCKNVIGGFEC---TCEEGFEPGPMM-TCEDINECAQNPLLCA 2218
D DEC N CG N C N+ G ++C C ++ P+ C + C N L CA
Sbjct: 5471 QDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC--LKNCPPNDLECA 5528
Score = 237 bits (605), Expect = 1e-61
Identities = 157/457 (34%), Positives = 199/457 (43%), Gaps = 93/457 (20%)
Query: 2192 CEEGF---EPGPMMTCEDINECAQ-NPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKD 2247
C GF GP C D +ECA NP C+ C N G+Y C CP G + D R C+D
Sbjct: 5092 CPSGFTLDSVGPF--CADEDECAAGNP--CSHSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 2248 EDECEEGKHDCTEKQMECKNLIGTYMCI--CGPGYQRRPDGEGCVDENECQTKPGICENG 2305
DEC G+H C Q +C N IG+Y C+ CG G++R DG C D NECQ + C
Sbjct: 5148 IDECALGRHTCHAGQ-DCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQ- 5204
Query: 2306 RCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCC 2365
RC N GS+ C C G+ + C+D E QN+C+ +N +C
Sbjct: 5205 RCFNAIGSFHCGCEPGYQLKGRK--CMD------VNECRQNVCRPDQHCKNTRGGYKCI- 5255
Query: 2366 DGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA--DIDECKVIHDVCR-NGECVNDR 2422
LCP+G NG DIDECK CR N C N R
Sbjct: 5256 ----------------------DLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTR 5293
Query: 2423 GSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRS 2482
GSY C+C GY G C+D+NEC Q PKPC C NT GS++C CP G L DG+S
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKS 5353
Query: 2483 CKDLDECAT----------------------KQH---------------NCQFLCVNTIG 2505
C L+ +QH N + T
Sbjct: 5354 CAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRR 5413
Query: 2506 GFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSC 2565
CP G H +C+D +EC N + C+NT GS+ C C G+ L G +C
Sbjct: 5414 TIRKTCPEGSEASHDTCVDIDECE---NTDACQHECKNTFGSYQCICPPGYQLTHNGKTC 5470
Query: 2566 EDVDEC-EGNHRC--QHGCQNIIGGYRC---SCPQGY 2596
+D+DEC E N C C N+ G Y+C CP Y
Sbjct: 5471 QDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY 5507
Score = 213 bits (543), Expect = 2e-54
Identities = 160/496 (32%), Positives = 220/496 (44%), Gaps = 100/496 (20%)
Query: 929 TRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAW 988
++G QCPSG TLD+ G C D ++EC AG + C S A
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCAD-----------EDECA---AG----NPCSHSCHNAM 5125
Query: 989 GTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGK-CRNT 1047
GT C CP+G A T +DI+EC + C G+ C NT
Sbjct: 5126 GTYYCS-------------CPKGLTIAADGRT-----CQDIDECALGRHTCHAGQDCDNT 5167
Query: 1048 IGSFKC--RCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGF 1105
IGS++C RC SGF S+ +C DI+EC+ S R C N G F C C+ GY+
Sbjct: 5168 IGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQ--- 5222
Query: 1106 MMMKNCMDIDECQRDPLLCRGGV-CHNTEGSYRCE--CPPGHQLSPNISACIDINECELS 1162
+ + CMD++EC+++ +CR C NT G Y+C CP G + N CIDI+EC+
Sbjct: 5223 LKGRKCMDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGMTKAEN-GTCIDIDECKDG 5279
Query: 1163 AHLCP-NGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYEC 1221
H C N C N G Y+C C GY S C+DI+EC + C C+N+ GS++C
Sbjct: 5280 THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKC 5339
Query: 1222 SCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIP----------------------- 1258
C PG L+ D +SC ++ PN N+
Sbjct: 5340 ICPPGQHLLGDGKSCAGLERL---PNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYS 5396
Query: 1259 --GEY--------------RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGS 1302
EY R C +G AS D TCVD++EC+ N + C C+NT GS
Sbjct: 5397 SYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD--TCVDIDECE-NTDAC-QHECKNTFGS 5452
Query: 1303 FICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC---SCSPGWIGDGI 1359
+ C C GY C DI+EC +CG + +C N GS++C C P + D +
Sbjct: 5453 YQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPV 5512
Query: 1360 KCTDLDECSNGTHMCS 1375
L C C+
Sbjct: 5513 SGFCLKNCPPNDLECA 5528
Score = 212 bits (540), Expect = 4e-54
Identities = 137/394 (34%), Positives = 175/394 (44%), Gaps = 60/394 (15%)
Query: 1182 CNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDE 1241
C G+ FC D DEC+ N C C N+ G+Y CSC G + D R+C DIDE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 1242 CEDNPNICDGGQ-CTNIPGEYRCL--CYDGFMASEDMKTCVDVNECDLNPNICLSGTCEN 1298
C + C GQ C N G YRC+ C GF + D +C D+NEC + C C N
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQ-RCFN 5208
Query: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCS--CSPGWI- 1355
GSF C C+ GY K K C D+NEC +H C NT G +KC C G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRK--CMDVNECRQNVCRPDQH--CKNTRGGYKCIDLCPNGMTK 5264
Query: 1356 GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLN 1413
+ C D+DEC +GTH C + C+NT GSYRC+C GY G G C D++EC +
Sbjct: 5265 AENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPK 5324
Query: 1414 LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGL------ 1467
C + QC N PG ++C C G DGK+C ++ LPN + +NL
Sbjct: 5325 PCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLER--LPNYGTQYSSYNLARFSPVRNN 5381
Query: 1468 ---------------------------------FRCECEIGYELDRSGGNCTDVNECLDP 1494
R C G E S C D++EC +
Sbjct: 5382 YQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSE--ASHDTCVDIDECENT 5439
Query: 1495 TTCISGNCVNTPGSYICDCPPDFELNPTRVGCVD 1528
C C NT GSY C CPP ++L C D
Sbjct: 5440 DAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 211 bits (536), Expect = 1e-53
Identities = 147/444 (33%), Positives = 196/444 (44%), Gaps = 54/444 (12%)
Query: 1265 CYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDIN 1324
C GF C D +EC N C S +C N G++ C C G + C DI+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPC-SHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 1325 ECEIGAHNCGKHAVCTNTAGSFKC--SCSPGW--IGDGIKCTDLDECSNGTHMCSQHADC 1380
EC +G H C C NT GS++C C G+ DG+ C D++EC + H C
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPC---HQRC 5206
Query: 1381 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQ-CLNAPGGYRCE--CDMGFVP 1437
N +GS+ C C+ GY G C D++EC +N+ C Q C N GGY+C C G
Sbjct: 5207 FNAIGSFHCGCEPGYQLKGRKCMDVNECRQNV--CRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 1438 SADGKACEDIDECSL-PNICVFGT-CHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPT 1495
+ +G C DIDEC + C + C N G +RC C GY G C D+NEC
Sbjct: 5265 AENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVP 5323
Query: 1496 TCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRS----GNCYLDIR-----PRGDNGD 1546
+ C NTPGS+ C CPP L C G Y P +N
Sbjct: 5324 KPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQ 5383
Query: 1547 TA-----CSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPIT 1601
S+ + SL + T + CP EG + T
Sbjct: 5384 PQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCP--------------EGSEASHDT 5429
Query: 1602 VILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGI-CGP 1660
+ DIDEC+ CQ +C NTFGS+QC CP GY L + + C D++EC + CGP
Sbjct: 5430 CV--DIDECENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGP 5485
Query: 1661 G-TCYNTVGNYTCI---CPPDYMQ 1680
C+N G+Y CI CPP+Y +
Sbjct: 5486 NRMCFNMRGSYQCIDTPCPPNYQR 5509
Score = 208 bits (530), Expect = 5e-53
Identities = 113/273 (41%), Positives = 148/273 (54%), Gaps = 18/273 (6%)
Query: 2429 CKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDE 2488
C +G+T D G C D +EC A PC+ C N G+Y CSCPKG + DGR+C+D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDEC-AAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 2489 CATKQHNCQFL--CVNTIGGFTC--KCPPGF--TQHHTSCIDNNECTSDINLCGSKGICQ 2542
CA +H C C NTIG + C +C GF T SC D NEC + + C + C
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINEC-QESSPCHQR--CF 5207
Query: 2543 NTPGSFTCECQRGFSLDQTGSSCEDVDECEGNH-RCQHGCQNIIGGYRCS--CPQGYLQH 2599
N GSF C C+ G+ L G C DV+EC N R C+N GGY+C CP G +
Sbjct: 5208 NAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNG-MTK 5264
Query: 2600 YQWNQCVDENECLSA-HICG-GASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQA 2657
+ C+D +EC H C C NT GSY+C+CP G++ + C DINEC
Sbjct: 5265 AENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPK 5324
Query: 2658 PCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGM 2690
PC++ CSNT G + C CPPG +G G +G+
Sbjct: 5325 PCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGL 5357
Score = 204 bits (518), Expect = 1e-51
Identities = 139/448 (31%), Positives = 196/448 (43%), Gaps = 66/448 (14%)
Query: 1132 TEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPD 1191
++G +CP G L C D +EC + + C + C N +G Y C+C G D
Sbjct: 5084 SKGDRSNQCPSGFTLDSVGPFCADEDECA-AGNPCSHS-CHNAMGTYYCSCPKGLTIAAD 5141
Query: 1192 RLFCVDIDECSIMNGGCETF--CTNSEGSYEC--SCQPGFALMPDQRSCTDIDECEDNPN 1247
C DIDEC++ C C N+ GSY C C GF D SC DI+EC+++
Sbjct: 5142 GRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP 5201
Query: 1248 ICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGT-CENTKGSFICH 1306
+C N G + C C G+ + C+DVNEC N+C C+NT+G + C
Sbjct: 5202 CHQ--RCFNAIGSFHCGCEPGYQLKG--RKCMDVNEC--RQNVCRPDQHCKNTRGGYKCI 5255
Query: 1307 --CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGI--KCT 1362
C G + + T C DI+EC+ G H C + +C NT GS++C C G+ G+ C
Sbjct: 5256 DLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCM 5314
Query: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSE------NLNL 1414
D++EC C+ C NT GS++C+C G GDG +C L+ + NL
Sbjct: 5315 DINECEQVPKPCAHQ--CSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNL 5372
Query: 1415 CGNGQCLN------------------------------APGGYRCECDMGFVPSADGKAC 1444
N R C G S D C
Sbjct: 5373 ARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD--TC 5430
Query: 1445 EDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGN--C 1502
DIDEC + C C N G ++C C GY+L +G C D++ECL+ N C
Sbjct: 5431 VDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMC 5489
Query: 1503 VNTPGSYIC---DCPPDFELNPTRVGCV 1527
N GSY C CPP+++ +P C+
Sbjct: 5490 FNMRGSYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 195 bits (495), Expect = 6e-49
Identities = 155/488 (31%), Positives = 207/488 (42%), Gaps = 63/488 (12%)
Query: 2030 SNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKG 2089
S ++G CP GF+L S G C D + EC
Sbjct: 5082 SISKGDRSNQCPSGFTLDSVGPFCAD------------------------EDECAA---- 5113
Query: 2090 EGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQ-CINTDG 2147
G+PC + CP G I + D+DEC C GQ C NT G
Sbjct: 5114 ---GNPCSHSCHNAMGTYYCSCPKGL-TIAADGRTCQDIDECALGRHTCHAGQDCDNTIG 5169
Query: 2148 SYRC--ECPFGY--ILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMT 2203
SYRC C G+ G C D +EC +PC + C N IG F C CE G++
Sbjct: 5170 SYRCVVRCGSGFRRTSDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQL-KGRK 5227
Query: 2204 CEDINECAQNPLLCAFRCVNTYGSYEC--KCPVGYVLREDRRMCKDEDECEEGKHDCTEK 2261
C D+NEC QN C NT G Y+C CP G + + + C D DEC++G H C
Sbjct: 5228 CMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNG-MTKAENGTCIDIDECKDGTHQCRYN 5286
Query: 2262 QMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDG 2321
Q+ C+N G+Y C+C GY+ + G C+D NEC+ P C + +C NT GS+ C C G
Sbjct: 5287 QI-CENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Query: 2322 FTASPNQDEC--LDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICP 2379
+ C L+ Y N+ + S RN + + + E
Sbjct: 5345 QHLLGDGKSCAGLERLPNYGTQYSSYNLARF-SPVRNNYQPQQHYRQYSHLYSSYSEYRN 5403
Query: 2380 FQGTVA-----FKKLCPHG-RGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGY 2433
+ +++ +K CP G DIDEC+ D C++ EC N GSY CIC GY
Sbjct: 5404 SRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENT-DACQH-ECKNTFGSYQCICPPGY 5461
Query: 2434 TPDITGTSCVDLNECNQAPKPC--NFICKNTEGSYQC---SCPKGYILQEDGRSCKDLDE 2488
G +C D++EC + C N +C N GSYQC CP Y Q D S L
Sbjct: 5462 QLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNY--QRDPVSGFCLKN 5519
Query: 2489 CATKQHNC 2496
C C
Sbjct: 5520 CPPNDLEC 5527
Score = 193 bits (491), Expect = 2e-48
Identities = 139/439 (31%), Positives = 191/439 (43%), Gaps = 69/439 (15%)
Query: 1024 PFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGR 1083
PF D +EC + C+H C N +G++ C C G + ++ R C DIDEC + C
Sbjct: 5103 PFCADEDECAA-GNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHA 5160
Query: 1084 GQ-CVNTPGDFEC--KCDEGYESGFMMMKNCMDIDECQRD-PLLCRGGVCHNTEGSYRCE 1139
GQ C NT G + C +C G+ + +C DI+ECQ P R C N GS+ C
Sbjct: 5161 GQDCDNTIGSYRCVVRCGSGFRRTSDGL-SCQDINECQESSPCHQR---CFNAIGSFHCG 5216
Query: 1140 CPPGHQLSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCA--CNPGYHSTPDRLFCV 1196
C PG+QL C+D+NEC ++C P+ C N G Y+C C P + + C+
Sbjct: 5217 CEPGYQLKGR--KCMDVNECR--QNVCRPDQHCKNTRGGYKCIDLC-PNGMTKAENGTCI 5271
Query: 1197 DIDECSIMNGGCE--TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC 1254
DIDEC C C N+ GSY C C G+ R C DI+ECE P C QC
Sbjct: 5272 DIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQC 5330
Query: 1255 TNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCEN------TKGSF----- 1303
+N PG ++C+C G D K+C + PN + N + ++
Sbjct: 5331 SNTPGSFKCICPPGQHLLGDGKSCAGLERL---PNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 1304 ---ICHCDMGYSG-KKGKTG----------------------CTDINECEIGAHNCGKHA 1337
H YS + +T C DI+ECE C
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NTDACQHE- 5445
Query: 1338 VCTNTAGSFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL---CK 1392
C NT GS++C C PG+ +G C D+DEC C + C N GSY+C+ C
Sbjct: 5446 -CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCP 5504
Query: 1393 EGYTGDGFTCTDLDECSEN 1411
Y D + L C N
Sbjct: 5505 PNYQRDPVSGFCLKNCPPN 5523
Score = 190 bits (483), Expect = 2e-47
Identities = 145/466 (31%), Positives = 190/466 (40%), Gaps = 51/466 (10%)
Query: 1207 GCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCY 1266
G + + S+G C GF L C D DEC N C C N G Y C C
Sbjct: 5076 GFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAG-NPC-SHSCHNAMGTYYCSCP 5133
Query: 1267 DGFMASEDMKTCVDVNECDLNPNICLSG-TCENTKGSFIC--HCDMGYSGKKGKTGCTDI 1323
G + D +TC D++EC L + C +G C+NT GS+ C C G+ C DI
Sbjct: 5134 KGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDI 5193
Query: 1324 NECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNT 1383
NEC+ + H C N GSF C C PG+ G KC D++EC ++C CKNT
Sbjct: 5194 NECQ---ESSPCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNT 5248
Query: 1384 MGSYRC--LCKEGYT-GDGFTCTDLDECSENLNLCGNGQ-CLNAPGGYRCECDMGFVPSA 1439
G Y+C LC G T + TC D+DEC + + C Q C N G YRC C G+
Sbjct: 5249 RGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Query: 1440 DGKACEDIDEC-SLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCI 1498
G+ C DI+EC +P C C N PG F+C C G L G +C + + T
Sbjct: 5309 VGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQY 5367
Query: 1499 SGNCVNTPGSYICDCPPD-------------FELNPTRVGCVDTRSGNCYLDIRPRGDNG 1545
S + + P E +R TR IR G
Sbjct: 5368 SSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRR-----TIRKTCPEG 5422
Query: 1546 DTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNT-SEYKILCPGGEGFRPNPITVIL 1604
A + C + + T NT Y+ +CP G N T
Sbjct: 5423 SEASHD----------TCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKT--C 5470
Query: 1605 EDIDECQELPGLCQGGK-CINTFGSFQC---RCPTGYYLNEDTRVC 1646
+DIDEC E C + C N GS+QC CP Y + + C
Sbjct: 5471 QDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 189 bits (481), Expect = 3e-47
Identities = 150/485 (30%), Positives = 200/485 (41%), Gaps = 83/485 (17%)
Query: 1876 CHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGF-ILSHNNDCIDVDEC 1934
C +GF + C D +EC + +C N +G++ C C G I + C D+DEC
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDEC 5151
Query: 1935 ASGNGNLCRNGQ-CINTVGSFQC--QCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQN 1991
A G + C GQ C NT+GS++C +C G+ DG +C DINEC E C C N
Sbjct: 5152 ALGR-HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINEC-QESSPCHQ-RCFN 5208
Query: 1992 LDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGT-CSNTEGSFKC--LCPEGFSLSS 2048
GS+ C C PGY L+ KC D++EC +C C NT G +KC LCP G +
Sbjct: 5209 AIGSFHCGCEPGYQLKGRKCMDVNEC--RQNVCRPDQHCKNTRGGYKCIDLCPNGMT--- 5263
Query: 2049 SGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFR 2108
K E G C +C + CE ++R
Sbjct: 5264 ---------------KAENGTCIDIDECKDGTHQC-------RYNQICE----NTRGSYR 5297
Query: 2109 QICPYGSGIIVGPDDSAVDMDECKE-PDVCKHGQCINTDGSYRCECPFGYILAGNECVDT 2167
+CP G G +D++EC++ P C H QC NT GS++C CP G L G+
Sbjct: 5298 CVCPRGYR-SQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGD----- 5350
Query: 2168 DECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGS 2227
G C G + G + + P+ N Q ++Y
Sbjct: 5351 -----GKSCA-GLERLPNYGTQYSSYNLARFSPVRN----NYQPQQHYRQYSHLYSSYSE 5400
Query: 2228 YECK--------------CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYM 2273
Y CP G D C D DECE + Q ECKN G+Y
Sbjct: 5401 YRNSRTSLSRTRRTIRKTCPEGSEASHD--TCVDIDECE----NTDACQHECKNTFGSYQ 5454
Query: 2274 CICGPGYQRRPDGEGCVDENECQTKPGIC-ENGRCLNTRGSYTC---ECNDGFTASPNQD 2329
CIC PGYQ +G+ C D +EC + C N C N RGSY C C + P
Sbjct: 5455 CICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSG 5514
Query: 2330 ECLDN 2334
CL N
Sbjct: 5515 FCLKN 5519
Score = 186 bits (471), Expect = 4e-46
Identities = 150/479 (31%), Positives = 198/479 (41%), Gaps = 91/479 (18%)
Query: 1391 CKEGYTGD--GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDID 1448
C G+T D G C D DEC+ N C + C NA G Y C C G +ADG+ C+DID
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 1449 ECSLP-NICVFGT-CHNLPGLFRC--ECEIGYELDRSGGNCTDVNECLDPTTCISGNCVN 1504
EC+L + C G C N G +RC C G+ G +C D+NEC + + C C N
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ-RCFN 5208
Query: 1505 TPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDI-RPRGDNGDTACSNEIGVGVSKASCC 1563
GS+ C C P ++L + C+D C ++ RP D C N G
Sbjct: 5209 AIGSFHCGCEPGYQLKGRK--CMDVNE--CRQNVCRP-----DQHCKNTRG--------- 5250
Query: 1564 CSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGK-C 1622
G C LCP G N + DIDEC++ C+ + C
Sbjct: 5251 -------GYKCID-----------LCPNGMTKAENGTCI---DIDECKDGTHQCRYNQIC 5289
Query: 1623 INTFGSFQCRCPTGYYLNEDTRVCDDVNECE-TPGICGPGTCYNTVGNYTCICPPDYMQV 1681
NT GS++C CP GY R C D+NECE P C C NT G++ CICPP +
Sbjct: 5290 ENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCA-HQCSNTPGSFKCICPPGQHLL 5348
Query: 1682 NGGNNCMDMRRSLCY----------------RNYYADNQTCDGELLFNMTKKMCCCSYNI 1725
G +C + R Y NY L++ + ++
Sbjct: 5349 GDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSL 5408
Query: 1726 GRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINM 1785
R + CP S T VDIDEC E C++ C N
Sbjct: 5409 SRTRRTIRKTCPEGSEASHDTC-----------------VDIDEC-ENTDACQH-ECKNT 5449
Query: 1786 VGSFRCECPVGFFYNDKLLVCEDIDECQNGPV-CQRNAECINTAGSYRC---DCKPGYR 1840
GS++C CP G+ C+DIDEC V C N C N GSY+C C P Y+
Sbjct: 5450 FGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQ 5508
Score = 181 bits (460), Expect = 7e-45
Identities = 138/456 (30%), Positives = 191/456 (41%), Gaps = 78/456 (17%)
Query: 1632 RCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMR 1691
+CP+G+ L+ C D +EC C +C+N +G Y C CP G C D+
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAAGNPCSH-SCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 1692 RSLCYRNYYADNQTCDGEL-----------LFNMTKKMCCCSYNIGRAWNKPCEQCPIPS 1740
R+ Q CD + F T C + PC Q +
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNA 5209
Query: 1741 TDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCE-NGVCINMVGSFRC--ECPVGF 1797
F CG + PG+ + +D++ECR+ VC + C N G ++C CP G
Sbjct: 5210 IGSFH--CGCE-PGY--QLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNGM 5262
Query: 1798 FYNDKLLVCEDIDECQNGP-VCQRNAECINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQE 1855
+ C DIDEC++G C+ N C NT GSYRC C GYR G+ C D NEC++
Sbjct: 5263 TKAEN-GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQ 5321
Query: 1856 IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDI----------------------- 1892
+P C+H QC +T GSF C+C G D C +
Sbjct: 5322 VPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRN 5380
Query: 1893 ------------------NECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDEC 1934
+E R TI C G SH+ C+D+DEC
Sbjct: 5381 NYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRK---TCPEGSEASHDT-CVDIDEC 5436
Query: 1935 ASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPG-TCQNLD 1993
N + C++ +C NT GS+QC C GY++ +G+TC DI+ECL + C P C N+
Sbjct: 5437 E--NTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMR 5493
Query: 1994 GSYRCI---CPPGYSLQNEKCEDIDECVEEPEICAL 2026
GSY+CI CPP Y + C CAL
Sbjct: 5494 GSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECAL 5529
Score = 177 bits (448), Expect = 2e-43
Identities = 110/336 (32%), Positives = 147/336 (43%), Gaps = 53/336 (15%)
Query: 2390 CPHGRGFMTNGA---DIDECKVIHDVCRNGE-CVNDRGSYHCI--CKTGYTPDITGTSCV 2443
CP G +G DIDEC + C G+ C N GSY C+ C +G+ G SC
Sbjct: 5132 CPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ 5191
Query: 2444 DLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNT 2503
D+NEC ++ PC+ C N GS+ C C GY L+ GR C D++EC C NT
Sbjct: 5192 DINECQES-SPCHQRCFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQNVCRPDQHCKNT 5248
Query: 2504 IGGFTC--KCPPGFTQ-HHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQ 2560
GG+ C CP G T+ + +CID +EC + C IC+NT GS+ C C RG+
Sbjct: 5249 RGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQG 5308
Query: 2561 TGSSCEDVDECEGNHR-CQHGCQNIIGGYRCSCPQG------------------------ 2595
G C D++ECE + C H C N G ++C CP G
Sbjct: 5309 VGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYS 5368
Query: 2596 -------------YLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQF 2642
Y + Q S + S T + + CP G +
Sbjct: 5369 SYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD 5428
Query: 2643 SGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGY 2678
+ C DI+EC + A C + C NT G Y C CPPGY
Sbjct: 5429 T--CVDIDECENTDA-CQHECKNTFGSYQCICPPGY 5461
Score = 172 bits (436), Expect = 4e-42
Identities = 130/428 (30%), Positives = 177/428 (41%), Gaps = 81/428 (18%)
Query: 450 TDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE-CIDVDECEK-NPCAGGECINN 507
+DY Q+ L + G +C GF LD G C D DEC NPC+ C N
Sbjct: 5066 SDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS-CHNA 5124
Query: 508 QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGR-CINTDGSFHCV--CNAGFHVT 564
G+Y C C G C+DIDEC C+ G+ C NT GS+ CV C +GF T
Sbjct: 5125 MGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRT 5184
Query: 565 RDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICM 624
DG +C+D++EC + C + C N GSF C C+PG+QL GR C D+NEC
Sbjct: 5185 SDGLSCQDINECQESSPC-HQRCFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQNVCRP 5241
Query: 625 NGRCVNTDGSYRC-ECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSEC 683
+ C NT G Y+C + P + C+D EC
Sbjct: 5242 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDI-------------------------DEC 5276
Query: 684 CCASTEYAFGEPCQPCPAQNSAEYQALCSSG---PGMTSAGSDINECALDPDICPNGICE 740
+ + + + C+ Y+ +C G G+ DINEC P C + C
Sbjct: 5277 KDGTHQCRYNQICE----NTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ-CS 5331
Query: 741 NLRGTYKCICNSGYEVDSTGKNCVDINEC-----------------VLNS---------- 773
N G++KCIC G + GK+C + V N+
Sbjct: 5332 NTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQY 5391
Query: 774 --LLCDNGQCRN-------TPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNS 824
L + RN T + TCP+G D TC DIDECE++ CKN+
Sbjct: 5392 SHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD--TCVDIDECENTDACQHECKNT 5449
Query: 825 PGSFICEC 832
GS+ C C
Sbjct: 5450 FGSYQCIC 5457
Score = 162 bits (411), Expect = 3e-39
Identities = 143/458 (31%), Positives = 193/458 (42%), Gaps = 65/458 (14%)
Query: 711 CSSGPGMTSAG---SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN 767
C SG + S G +D +ECA + C + C N GTY C C G + + G+ C DI+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 768 ECVLNSLLCDNGQ-CRNTPGSFVCT--CPKGFIYKPDLKTCEDIDEC-ESSPCINGVCKN 823
EC L C GQ C NT GS+ C C GF D +C+DI+EC ESSPC + C N
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPC-HQRCFN 5208
Query: 824 SPGSFICECSSESTLDPTKTICIETIKGTCWQTVI--DGRCEININGATLKSQCCSSLGA 881
+ GSF C C L K C++ C Q V D C+ G C + +
Sbjct: 5209 AIGSFHCGCEPGYQLKGRK--CMDV--NECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 882 AWGSPCT----------LCQVDPICG-----------KGY-SRIKGTQCEDIDECEVFPG 919
A C C+ + IC +GY S+ G C DI+ECE P
Sbjct: 5265 AENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPK 5324
Query: 920 VCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDI-RLETCFLRYEDEECT--LPIAGRHR 976
C + C NT GSFKC CP G L G+ C + RL +Y P+ ++
Sbjct: 5325 PCAHQ-CSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQ 5383
Query: 977 MDACCCSVGAAWGT----EECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINEC 1032
+ + R + CP G + DI+EC
Sbjct: 5384 PQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCV-------DIDEC 5436
Query: 1033 KMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ-CVNTPG 1091
+ + C H +C+NT GS++C C G+ L + C DIDEC CG + C N G
Sbjct: 5437 ENTDA-CQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRG 5494
Query: 1092 DFEC---KCDEGYE----SGFMMMKNCMDID-ECQRDP 1121
++C C Y+ SGF +KNC D EC P
Sbjct: 5495 SYQCIDTPCPPNYQRDPVSGF-CLKNCPPNDLECALSP 5531
Score = 130 bits (327), Expect = 2e-29
Identities = 120/453 (26%), Positives = 176/453 (38%), Gaps = 92/453 (20%)
Query: 231 CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290
C GF + C D DEC A G +C N +G++ C CP G + + C+DID
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAA--GNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 291 ECSTIPGICEGGE-CTNTVSSYFC--KCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSN 347
EC+ C G+ C NT+ SY C +C GF + DG C D+ + C
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINE-----CQESSPCHQ 5204
Query: 348 QLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPE-YPPPPL 406
+ +I C C+ PG + C + E +C RP+ +
Sbjct: 5205 RCFNAIGSFHCGCE------PGYQLKGRKC-MDVNECRQNVC--------RPDQHCKNTR 5249
Query: 407 GPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQ-NGRC 465
G + P G E + + D C+ + C+ N C
Sbjct: 5250 GGYKCIDLCPNGMTKA-----------------ENGTCIDI---DECKDGTHQCRYNQIC 5289
Query: 466 IPTPGSCRCECNKGFQLDLRGE-CIDVDECEK--NPCAGGECINNQGSYTCQCRAGYQST 522
T GS RC C +G++ G C+D++ECE+ PCA +C N GS+ C C G
Sbjct: 5290 ENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLL 5348
Query: 523 LTRTECRDIDECLQNGR------------ICNNGR------------------------C 546
C ++ G + NN +
Sbjct: 5349 GDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSL 5408
Query: 547 INTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLAS 606
T + C G + D C D+DEC + C + C N GS++CIC PG+QL
Sbjct: 5409 SRTRRTIRKTCPEGSEASHD--TCVDIDECENTDACQHE-CKNTFGSYQCICPPGYQLTH 5465
Query: 607 DGRYCKDINECETPGI-C-MNGRCVNTDGSYRC 637
+G+ C+DI+EC + C N C N GSY+C
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 122 bits (307), Expect = 4e-27
Identities = 59/137 (43%), Positives = 73/137 (53%), Gaps = 5/137 (3%)
Query: 2546 GSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQC 2605
G + +C GF+LD G C D DEC + C H C N +G Y CSCP+G C
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTC 5145
Query: 2606 VDENEC-LSAHIC-GGASCHNTLGSYKCM--CPAGFQYEQFSGGCQDINECGSAQAPCSY 2661
D +EC L H C G C NT+GSY+C+ C +GF+ CQDINEC +PC
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINEC-QESSPCHQ 5204
Query: 2662 GCSNTEGGYLCGCPPGY 2678
C N G + CGC PGY
Sbjct: 5205 RCFNAIGSFHCGCEPGY 5221
Score = 114 bits (285), Expect = 1e-24
Identities = 108/428 (25%), Positives = 160/428 (37%), Gaps = 91/428 (21%)
Query: 272 KCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331
+CP+G L+ V C D DEC+ G C N + +Y+C CP G
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECAA--GNPCSHSCHNAMGTYYCSCPKGL------------ 5136
Query: 332 RPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSV 391
T +GR + + C C + T+ C +R F +
Sbjct: 5137 ------TIAADGRTCQDIDECALGRHTCHAGQDCDN---TIGSYRCVVRCGSGFRRTSDG 5187
Query: 392 PMV--IPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNV 449
I E P + G PG Q+ + + + VN
Sbjct: 5188 LSCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQL--------------KGRKCMDVN- 5232
Query: 450 TDYCQLVRYLCQ-NGRCIPTPGSCRCE--CNKGFQLDLRGECIDVDECEK--NPCAGGE- 503
+ + +C+ + C T G +C C G G CID+DEC+ + C +
Sbjct: 5233 ----ECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQI 5288
Query: 504 CINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHV 563
C N +GSY C C GY+S C DI+EC Q + C + +C NT GSF C+C G H+
Sbjct: 5289 CENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHL 5347
Query: 564 TRDGKNCEDMD-------ECSIRNMCLNGMCINE-------------------------- 590
DGK+C ++ + S N+ N
Sbjct: 5348 LGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTS 5407
Query: 591 ----DGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVG 646
+ + C G + + D C DI+ECE C + C NT GSY+C C PG +
Sbjct: 5408 LSRTRRTIRKTCPEGSEASHDT--CVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLT 5464
Query: 647 LDGRVCVD 654
+G+ C D
Sbjct: 5465 HNGKTCQD 5472
Score = 109 bits (273), Expect = 3e-23
Identities = 135/484 (27%), Positives = 172/484 (35%), Gaps = 85/484 (17%)
Query: 168 CTYGFT----GPQC--ERDYRTG-PCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHP 220
C GFT GP C E + G PC N M S C K L A GR
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCS---CPKGLTIAADGRTC-QD 5147
Query: 221 CEMCPAQPHPCRRG---------FIPNIRTGA----------CQDVDECQAIPGLCQGGN 261
+ C H C G + +R G+ CQD++ECQ Q
Sbjct: 5148 IDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQ--R 5205
Query: 262 CINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGE-CTNTVSSYFC--KCPPG 318
C N +GSF C C G++L +KC D++EC +C + C NT Y C CP G
Sbjct: 5206 CFNAIGSFHCGCEPGYQLK--GRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPNG 5261
Query: 319 FYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCP 378
+ +GT CID+ C R + + +C C G S GV
Sbjct: 5262 MTKAENGT-CIDIDE--CKDGTHQCRYNQICENTRGSYRCVCPRGYR-SQGVG------- 5310
Query: 379 IRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPS 438
R D N+ VP + P I P G P Y S
Sbjct: 5311 -RPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSS 5369
Query: 439 REPPRVLPVNVTD------------YCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRG 486
R PV Y Y T + R C +G +
Sbjct: 5370 YNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEAS-HD 5428
Query: 487 ECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICN-NGR 545
C+D+DECE EC N GSY C C GYQ T C+DIDECL+ C N
Sbjct: 5429 TCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Query: 546 CINTDGSFHCV---CNAGFHVTRDG------KNCEDMD-ECSIRNMCLN--------GMC 587
C N GS+ C+ C + RD KNC D EC++ L G+
Sbjct: 5489 CFNMRGSYQCIDTPCPPNYQ--RDPVSGFCLKNCPPNDLECALSPYALEYKLVSLPFGIA 5546
Query: 588 INED 591
N+D
Sbjct: 5547 TNQD 5550
Score = 87.8 bits (216), Expect = 1e-16
Identities = 73/267 (27%), Positives = 97/267 (36%), Gaps = 68/267 (25%)
Query: 67 CCPGWKTLPGGNQCIVPI----CRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIR 122
C G T G C I C CG GF + +C Q C S C+ R
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSC---QDINECQESS--PCHQR 5205
Query: 123 CMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYR 182
C N + HC C+ GY L G +C+ N C C D
Sbjct: 5206 CFN--AIGSFHCGCEPGYQ-------------LKGRKCMDVNECRQNV------CRPD-- 5242
Query: 183 TGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTG 242
Q C+ G C ++CP + G
Sbjct: 5243 ----------QHCKNTRGGYKCI----------------DLCP--------NGMTKAENG 5268
Query: 243 ACQDVDECQAIPGLCQGGN-CINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG 301
C D+DEC+ C+ C NT GS+ C CP G++ V + C DI+EC +P C
Sbjct: 5269 TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-A 5327
Query: 302 GECTNTVSSYFCKCPPGFYTSPDGTRC 328
+C+NT S+ C CPPG + DG C
Sbjct: 5328 HQCSNTPGSFKCICPPGQHLLGDGKSC 5354
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 220 bits (561), Expect = 1e-56
Identities = 143/412 (34%), Positives = 193/412 (46%), Gaps = 46/412 (11%)
Query: 1155 DINECELSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC-SIMNGGCETFC 1212
D++EC C + C N Y+C+C PGY + C DIDEC + +NGGC C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECGNELNGGCVHDC 102
Query: 1213 TNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMAS 1272
N G+Y C+C GF L D +C D+DEC +N C C N+ G Y C C +GF S
Sbjct: 103 LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLS 161
Query: 1273 EDMKTCVDVNECDL---NPNICLSGTC-ENTKGSFICHCDMGYSGKKGKTGCTDINECEI 1328
++ TC+ +E L N + S C E +GS C C G+ K + C I C
Sbjct: 162 DNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCNH 219
Query: 1329 GAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDEC------SNGTHM------- 1373
G C +H+ C +TA +CSC P + DG C + ++ SN T +
Sbjct: 220 GNGGC-QHS-CDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRV 277
Query: 1374 --------CSQH-----ADCKNTMGSYRCLCKEGYTG--DGFTCTDLDECSENLNLCGNG 1418
C+ + CK+T C C G+T DG TC D+DEC C +
Sbjct: 278 KRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF 337
Query: 1419 QCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYEL 1478
C N G + C C GF D K+C+D+DECSL C +C N PG F C C GY L
Sbjct: 338 -CKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH-SCINHPGTFACACNRGYTL 395
Query: 1479 DRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTR 1530
+C D NEC CVNT GSY C C P ++L+ + CV+ +
Sbjct: 396 -YGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVK 446
Score = 212 bits (540), Expect = 4e-54
Identities = 142/454 (31%), Positives = 190/454 (41%), Gaps = 72/454 (15%)
Query: 2205 EDINECAQNPLLCAFR--CVNTYGSYECKCPVGYVLREDRRMCKDEDEC-EEGKHDCTEK 2261
ED++ECAQ C C NT SY+C C GY + + R C+D DEC E C
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGY--QGEGRQCEDIDECGNELNGGCVH- 100
Query: 2262 QMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDG 2321
+C N+ G Y C C G+ DG C+D +EC G C++ C+N GSY C C +G
Sbjct: 101 --DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEG 157
Query: 2322 FTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQ 2381
F S NQ C+ E + C + G C+ P +
Sbjct: 158 FFLSDNQHTCIHRSE-----------------------EGLSCMNKDHGCSHICKEAP-R 193
Query: 2382 GTVAFKKLCPHGRGFMTNGAD-IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGT 2440
G+VA + C G N D I C + C++ C + C C Y G
Sbjct: 194 GSVACE--CRPGFELAKNQRDCILTCNHGNGGCQHS-CDDTADGPECSCHPQYKMHTDGR 250
Query: 2441 SCVD----------------------------LNECNQAPKPCNFICKNTEGSYQCSCPK 2472
SC++ + C C+ CK+T CSCP
Sbjct: 251 SCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPV 310
Query: 2473 GYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGF--TQHHTSCIDNNECTS 2530
G+ LQ DG++CKD+DEC T+ C C N +G F C C GF SC D +EC+
Sbjct: 311 GFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSL 370
Query: 2531 DINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE-GNHRCQHGCQNIIGGYR 2589
D S C N PG+F C C RG++L + C D +EC N CQ C N +G Y
Sbjct: 371 DRTCDHS---CINHPGTFACACNRGYTL-YGFTHCGDTNECSINNGGCQQVCVNTVGSYE 426
Query: 2590 CSCPQGYLQHYQWNQCVDENECLSAHICGGASCH 2623
C C GY H+ CV+ L + S H
Sbjct: 427 CQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVSLH 460
Score = 187 bits (476), Expect = 1e-46
Identities = 137/426 (32%), Positives = 187/426 (43%), Gaps = 48/426 (11%)
Query: 1930 DVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTC 1989
DVDECA G + + C NT S++C C GY+ +GR C DI+EC E C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDC 102
Query: 1990 QNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLS 2047
N+ G+YRC C G+ L ++ C D+DEC+E C TC N GS++C C EGF LS
Sbjct: 103 LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQ-HTCVNVMGSYECCCKEGFFLS 161
Query: 2048 SSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPC----ELCPTEP 2103
+ C + EG C + ++H C C EL +
Sbjct: 162 DNQHTC-------IHRSEEGLSCMN---KDHGCSHICKEAPRGSVACECRPGFELAKNQR 211
Query: 2104 DEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNE 2163
D C +G+G D D EC C ++TDG C +L E
Sbjct: 212 DCILT--CNHGNGGCQHSCDDTADGPECS----CHPQYKMHTDGR-SCLEREDTVLEVTE 264
Query: 2164 C-----VDTDE----------CSVGNPCGNGTCKNVIGGFECTCEEGFEPG-PMMTCEDI 2207
VD D+ C+V N + TCK+ G C+C GF TC+DI
Sbjct: 265 SNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDI 324
Query: 2208 NECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKN 2267
+EC C C N GS++C C G+ L D + C+D DEC + C C N
Sbjct: 325 DECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDR-TCDH---SCIN 380
Query: 2268 LIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPN 2327
GT+ C C GY C D NEC G C+ C+NT GSY C+C+ G+ N
Sbjct: 381 HPGTFACACNRGYTLY-GFTHCGDTNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLHWN 438
Query: 2328 QDECLD 2333
+ +C++
Sbjct: 439 KKDCVE 444
Score = 184 bits (466), Expect = 1e-45
Identities = 129/423 (30%), Positives = 196/423 (46%), Gaps = 27/423 (6%)
Query: 1837 PGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC 1895
P R + G D +EC + + C + C +T S+ C C G++ Q C DI+EC
Sbjct: 33 PPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDEC 90
Query: 1896 ERDACGNGT--CRNTIGSFNCRCNHGFILSHN-NDCIDVDECASGNGNLCRNGQCINTVG 1952
+ G C N G++ C C GF+L+H+ ++C+DVDEC NG C++ C+N +G
Sbjct: 91 GNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGG-CQH-TCVNVMG 148
Query: 1953 SFQCQCNEGYEVAPDGRTCVDINE----CLLEPRKCAPGTCQNLDGSYRCICPPGYSLQN 2008
S++C C EG+ ++ + TC+ +E C+ + C+ + GS C C PG+ L
Sbjct: 149 SYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAK 208
Query: 2009 EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGG 2068
+ + I C C +C +T +C C + + + GR C + R E
Sbjct: 209 NQRDCILTCNHGNGGCQ-HSCDDTADGPECSCHPQYKMHTDGRSCLE-REDTVLEVTESN 266
Query: 2069 KCSSPKSRNHSKQECC---CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSA 2125
S K+ CA+ G C+ + CP G + + +
Sbjct: 267 TTSVVDGDKRVKRRLLMETCAVNNGGCDRTCK----DTSTGVHCSCPVGFTLQLD-GKTC 321
Query: 2126 VDMDECKEPDV-CKHGQCINTDGSYRCECPFGYILAGNE--CVDTDECSVGNPCGNGTCK 2182
D+DEC+ + C H C N GS+ C C G+ L +E C D DECS+ C + +C
Sbjct: 322 KDIDECQTRNGGCDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDH-SCI 379
Query: 2183 NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDR 2242
N G F C C G+ C D NEC+ N C CVNT GSYEC+C GY L ++
Sbjct: 380 NHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNK 439
Query: 2243 RMC 2245
+ C
Sbjct: 440 KDC 442
Score = 178 bits (452), Expect = 6e-44
Identities = 139/441 (31%), Positives = 198/441 (44%), Gaps = 47/441 (10%)
Query: 723 DINECALDPDIC-PNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNG-- 779
D++ECA D C + +C+N +YKC C GY+ + G+ C DI+EC N L NG
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGE--GRQCEDIDECG-NEL---NGGC 98
Query: 780 --QCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPCINGVCKNSPGSFICECSSES 836
C N PG++ CTC GF+ D C D+DEC E++ C N GS+ C C
Sbjct: 99 VHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGF 158
Query: 837 TLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPIC 896
L + CI + +G +N K CS + C+ C
Sbjct: 159 FLSDNQHTCIHRSE--------EGLSCMN------KDHGCSHICKEAPRGSVACE----C 200
Query: 897 GKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLE 956
G+ K Q + I C G C++ C +T +C C + GR CL+ E
Sbjct: 201 RPGFELAKN-QRDCILTCNHGNGGCQHS-CDDTADGPECSCHPQYKMHTDGRSCLE--RE 256
Query: 957 TCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFAT 1016
L + T + G R+ A C+ + CP GF
Sbjct: 257 DTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCP--VGFTL 314
Query: 1017 KEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRI 1076
+ +GK KDI+EC+ C H C+N +GSF C C GF L ++E++C D+DEC
Sbjct: 315 Q--LDGKTC-KDIDECQTRNGGCDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDEC-- 368
Query: 1077 SPDLCGRGQCVNTPGDFECKCDEGYE-SGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGS 1135
S D C+N PG F C C+ GY GF +C D +EC + C+ VC NT GS
Sbjct: 369 SLDRTCDHSCINHPGTFACACNRGYTLYGF---THCGDTNECSINNGGCQ-QVCVNTVGS 424
Query: 1136 YRCECPPGHQLSPNISACIDI 1156
Y C+C PG++L N C+++
Sbjct: 425 YECQCHPGYKLHWNKKDCVEV 445
Score = 177 bits (449), Expect = 1e-43
Identities = 120/368 (32%), Positives = 162/368 (44%), Gaps = 36/368 (9%)
Query: 490 DVDECEK--NPC-AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNG-- 544
DVDEC + + C A C N SY C C+ GYQ +C DIDEC G N G
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGE--GRQCEDIDEC---GNELNGGCV 99
Query: 545 -RCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQ 603
C+N G++ C C GF + DG NC D+DEC N C+N GS++C CK GF
Sbjct: 100 HDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFF 159
Query: 604 LASDGRYCKDINECETPGICMNGR------CVNTD-GSYRCECFPGLAVGLDGRVCVDTH 656
L+ + C I+ E CMN C GS CEC PG + + R C+
Sbjct: 160 LSDNQHTC--IHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCI--- 214
Query: 657 MRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPG 716
TC G G C EC C +Y + C + + S+
Sbjct: 215 --LTCNHG--NGGCQHSCDDTADGPECSC-HPQYKMHTDGRSCLEREDTVLEVTESNTTS 269
Query: 717 MTSAGSDINE------CALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECV 770
+ + CA++ C + C++ C C G+ + GK C DI+EC
Sbjct: 270 VVDGDKRVKRRLLMETCAVNNGGC-DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQ 328
Query: 771 LNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFIC 830
+ CD+ C+N GSF C C KGF D K+C+D+DEC + C N PG+F C
Sbjct: 329 TRNGGCDH-FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFAC 387
Query: 831 ECSSESTL 838
C+ TL
Sbjct: 388 ACNRGYTL 395
Score = 173 bits (438), Expect = 3e-42
Identities = 130/452 (28%), Positives = 175/452 (38%), Gaps = 78/452 (17%)
Query: 2291 DENECQTKPGICE-NGRCLNTRGSYTCECNDGFTASPNQ----DECLDNREGYCFTEVLQ 2345
D +EC C + C NT SY C C G+ Q DEC + G C + L
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCL- 103
Query: 2346 NMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDE 2405
N C C F G + L G N D+DE
Sbjct: 104 ----------NIPGNYRCTC--------------FDGFM----LAHDGH----NCLDVDE 131
Query: 2406 CKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNE----CNQAPKPCNFICKN 2461
C + C++ CVN GSY C CK G+ +C+ +E C C+ ICK
Sbjct: 132 CLENNGGCQH-TCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKE 190
Query: 2462 T-EGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHT 2520
GS C C G+ L ++ R C + C CQ C +T G C C P + H
Sbjct: 191 APRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTD 248
Query: 2521 --SCIDNNEC--------------------------TSDINLCGSKGICQNTPGSFTCEC 2552
SC++ + T +N G C++T C C
Sbjct: 249 GRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSC 308
Query: 2553 QRGFSLDQTGSSCEDVDECEG-NHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENEC 2611
GF+L G +C+D+DEC+ N C H C+NI+G + C C +G+ C D +EC
Sbjct: 309 PVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDEC 368
Query: 2612 LSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYL 2671
C SC N G++ C C G+ F+ C D NEC C C NT G Y
Sbjct: 369 SLDRTCDH-SCINHPGTFACACNRGYTLYGFTH-CGDTNECSINNGGCQQVCVNTVGSYE 426
Query: 2672 CGCPPGY-FRIGQGHCVSGMGMGRGNPEPPVS 2702
C C PGY + CV G+ + P VS
Sbjct: 427 CQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVS 458
Score = 170 bits (430), Expect = 2e-41
Identities = 131/441 (29%), Positives = 189/441 (42%), Gaps = 81/441 (18%)
Query: 1766 DIDECREIPGVCE-NGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 1824
D+DEC + C + +C N S++C C G Y + CEDIDEC N +C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPG--YQGEGRQCEDIDECGNELNGGCVHDC 102
Query: 1825 INTAGSYRCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTN 1883
+N G+YRC C G+ G C D +EC E C H C++ +GS+ C C GF +
Sbjct: 103 LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLS 161
Query: 1884 DDQTMCLDINE-----CERDACGNGTCRNT-IGSFNCRCNHGFILSHN-NDCIDVDECAS 1936
D+Q C+ +E +D + C+ GS C C GF L+ N DCI C
Sbjct: 162 DNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILT--CNH 219
Query: 1937 GNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRK------------- 1983
GNG C++ C +T +C C+ Y++ DGR+C++ + +LE +
Sbjct: 220 GNGG-CQH-SCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRV 277
Query: 1984 --------CAPG------TCQNLDGSYRCICPPGYSLQ--NEKCEDIDECVEEPEICALG 2027
CA TC++ C CP G++LQ + C+DIDEC C
Sbjct: 278 KRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCD-H 336
Query: 2028 TCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCAL 2087
C N GSF C C +GF L + + CQD+ +CS ++ +HS
Sbjct: 337 FCKNIVGSFDCGCKKGFKLLTDEKSCQDV-----------DECSLDRTCDHS-------- 377
Query: 2088 KGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDG 2147
C P C G + D +EC + C+NT G
Sbjct: 378 -----------CINHPGTF---ACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVG 423
Query: 2148 SYRCECPFGYILAGN--ECVD 2166
SY C+C GY L N +CV+
Sbjct: 424 SYECQCHPGYKLHWNKKDCVE 444
Score = 170 bits (430), Expect = 2e-41
Identities = 123/409 (30%), Positives = 165/409 (40%), Gaps = 54/409 (13%)
Query: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLN 1422
D+DEC+ G C A C+NT SY+C CK GY G+G C D+DEC LN CLN
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLN 104
Query: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSG 1482
PG YRC C GF+ + DG C D+DEC N TC N+ G + C C+ G+ L +
Sbjct: 105 IPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQ 164
Query: 1483 GNCTDVNE----CLDPTTCISGNCVNTP-GSYICDCPPDFELNPTRVGCVDT---RSGNC 1534
C +E C++ S C P GS C+C P FEL + C+ T +G C
Sbjct: 165 HTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGC 224
Query: 1535 YLDIRPRGDNGDTACSNEIGVGVSKASCC------------------------------- 1563
D + +C + + SC
Sbjct: 225 QHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLME 284
Query: 1564 -CSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKC 1622
C++ C+ ++ CP G + + T +DIDECQ G C C
Sbjct: 285 TCAVNNGG---CDRTCKDTSTGVHCSCPVGFTLQLDGKTC--KDIDECQTRNGGCDHF-C 338
Query: 1623 INTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVN 1682
N GSF C C G+ L D + C DV+EC C +C N G + C C Y +
Sbjct: 339 KNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTC-DHSCINHPGTFACACNRGY-TLY 396
Query: 1683 GGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNK 1731
G +C D C N N C + + C C WNK
Sbjct: 397 GFTHCGDTNE--CSIN----NGGCQQVCVNTVGSYECQCHPGYKLHWNK 439
Score = 169 bits (428), Expect = 4e-41
Identities = 125/413 (30%), Positives = 188/413 (45%), Gaps = 46/413 (11%)
Query: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGG---ECINNQGSYTCQC 515
LCQN TP S +C C G+Q + R +C D+DEC N GG +C+N G+Y C C
Sbjct: 61 LCQN-----TPTSYKCSCKPGYQGEGR-QCEDIDECG-NELNGGCVHDCLNIPGNYRCTC 113
Query: 516 RAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDE 575
G+ C D+DECL+N C + C+N GS+ C C GF ++ + C E
Sbjct: 114 FDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFLSDNQHTCIHRSE 172
Query: 576 CSIRNMCLNGMCIN-----EDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVN 630
+ M + C + GS C C+PGF+LA + R C I C C +
Sbjct: 173 EGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDC--ILTCNHGNGGCQHSCDD 230
Query: 631 TDGSYRCECFPGLAVGLDGRVCV----------DTHMRSTCYGGYKRGQCIKPLFGAVTK 680
T C C P + DGR C+ +++ S G + + + AV
Sbjct: 231 TADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNN 290
Query: 681 SECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICE 740
C + + G C CP + + G T DI+EC C + C+
Sbjct: 291 GGCDRTCKDTSTGVHCS-CPVGFTLQLD-------GKTC--KDIDECQTRNGGCDH-FCK 339
Query: 741 NLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGF-IYK 799
N+ G++ C C G+++ + K+C D++EC L+ CD+ C N PG+F C C +G+ +Y
Sbjct: 340 NIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDR-TCDH-SCINHPGTFACACNRGYTLY- 396
Query: 800 PDLKTCEDIDECE-SSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKG 851
C D +EC ++ VC N+ GS+ C+C L K C+E +KG
Sbjct: 397 -GFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVE-VKG 447
Score = 167 bits (423), Expect = 1e-40
Identities = 125/464 (26%), Positives = 195/464 (42%), Gaps = 101/464 (21%)
Query: 530 DIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECS--IRNMCLNGM 586
D+DEC Q C+ + C NT S+ C C G+ +G+ CED+DEC + C++
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNELNGGCVHD- 101
Query: 587 CINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCECFPGLAV 645
C+N G+++C C GF LA DG C D++EC E G C + CVN GSY C C G +
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH-TCVNVMGSYECCCKEGFFL 160
Query: 646 GLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSA 705
+ C+ ++ C + ++ C+ P + A
Sbjct: 161 SDNQHTCIHR-----------------------SEEGLSCMNKDHGCSHICKEAPRGSVA 197
Query: 706 EYQALCSSGPGMTSAGSDINECALDPDICPNGI---CENLRGTYKCICNSGYEVDSTGKN 762
C PG A + +C L + G C++ +C C+ Y++ + G++
Sbjct: 198 -----CECRPGFELAKNQ-RDCILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRS 251
Query: 763 CVD----------------------------INECVLNSLLCDNGQCRNTPGSFVCTCPK 794
C++ + C +N+ CD C++T C+CP
Sbjct: 252 CLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDR-TCKDTSTGVHCSCPV 310
Query: 795 GFIYKPDLKTCEDIDECESSPCING----VCKNSPGSFICECSSESTLDPTKTICIETIK 850
GF + D KTC+DIDEC++ NG CKN GSF C C L + C +
Sbjct: 311 GFTLQLDGKTCKDIDECQTR---NGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDV-- 365
Query: 851 GTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCED 910
C ++ T C + G C C +GY+ T C D
Sbjct: 366 ---------DECSLD---RTCDHSCINHPGTF---ACA-------CNRGYTLYGFTHCGD 403
Query: 911 IDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 954
+EC + G C+ +CVNT GS++CQC G L + C++++
Sbjct: 404 TNECSINNGGCQQ-VCVNTVGSYECQCHPGYKLHWNKKDCVEVK 446
Score = 163 bits (412), Expect = 3e-39
Identities = 131/460 (28%), Positives = 185/460 (40%), Gaps = 98/460 (21%)
Query: 987 AWGTEECE-ECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINEC-KMIPSLCTHGKC 1044
A G ++C + +NTP + C PG+ + G+ +DI+EC + C H C
Sbjct: 50 AQGLDDCHADALCQNTPTSYK-CSCKPGYQGE----GRQC-EDIDECGNELNGGCVHD-C 102
Query: 1045 RNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGY--- 1101
N G+++C C GF L + NC D+DEC + C + CVN G +EC C EG+
Sbjct: 103 LNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC-QHTCVNVMGSYECCCKEGFFLS 161
Query: 1102 ----------ESGFMMMKN-------CMDID------EC---------QRDPLL-CRGG- 1127
E G M C + EC QRD +L C G
Sbjct: 162 DNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGN 221
Query: 1128 -----VCHNTEGSYRCECPPGHQLSPNISACIDINECELSA------------------- 1163
C +T C C P +++ + +C++ + L
Sbjct: 222 GGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRL 281
Query: 1164 --HLCP--NG----RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNS 1215
C NG C + C+C G+ D C DIDEC NGGC+ FC N
Sbjct: 282 LMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNI 341
Query: 1216 EGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDM 1275
GS++C C+ GF L+ D++SC D+DEC + CD C N PG + C C G+
Sbjct: 342 VGSFDCGCKKGFKLLTDEKSCQDVDECSLD-RTCD-HSCINHPGTFACACNRGY-TLYGF 398
Query: 1276 KTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGK 1335
C D NEC +N C C NT GS+ C C GY K C ++ K
Sbjct: 399 THCGDTNECSINNGGC-QQVCVNTVGSYECQCHPGYKLHWNKKDCVEV-----------K 446
Query: 1336 HAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCS 1375
+ T+ + C GDG C +G H+ S
Sbjct: 447 GLLPTSVSPRVSLHCGKSGGGDGC----FLRCHSGIHLSS 482
Score = 158 bits (399), Expect = 8e-38
Identities = 216/853 (25%), Positives = 306/853 (35%), Gaps = 176/853 (20%)
Query: 1590 PGGEGFRPNPITVILEDIDEC-QELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDD 1648
P G G P ED+DEC Q L C NT S++C C GY + R C+D
Sbjct: 33 PPGRGRAAGP----QEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGY--QGEGRQCED 86
Query: 1649 VNEC--ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
++EC E G C C N GNY C C +M + G+NC+D+ L +N C
Sbjct: 87 IDECGNELNGGC-VHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECL------ENNGGC 139
Query: 1707 DGELLFNMTKKMCCCS----------------------YNIGRAWNKPCEQCPIPSTDEF 1744
+ M CCC N + C++ P S
Sbjct: 140 QHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSV--- 196
Query: 1745 ATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCEC-PVGFFYND-- 1801
A C RPGF ++ I C G C++ C + C C P + D
Sbjct: 197 ACEC---RPGF--ELAKNQRDCILTCNHGNGGCQHS-CDDTADGPECSCHPQYKMHTDGR 250
Query: 1802 KLLVCED-------------------------IDECQ-NGPVCQRNAECINTAGSYRCDC 1835
L ED ++ C N C R C +T+ C C
Sbjct: 251 SCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRT--CKDTSTGVHCSC 308
Query: 1836 KPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINE 1894
G+ G+ C D +ECQ C H C + VGSF C C GFK D+ C D++E
Sbjct: 309 PVGFTLQLDGKTCKDIDECQTRNGGCDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDE 367
Query: 1895 CERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSF 1954
C D + +C N G+F C CN G+ L C D +EC+ NG C+ C+NTVGS+
Sbjct: 368 CSLDRTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGG-CQQ-VCVNTVGSY 425
Query: 1955 QCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGT---CQNLDGSYRCI--CPPGYSLQNE 2009
+CQC+ GY++ + + CV++ L P +P C G C C G L ++
Sbjct: 426 ECQCHPGYKLHWNKKDCVEVKGLL--PTSVSPRVSLHCGKSGGGDGCFLRCHSGIHLSSD 483
Query: 2010 KC---EDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSY-CYAKF 2065
+ + E + C+L + PE S R +L S
Sbjct: 484 VTTIRTSVTFKLNEGK-CSLKNAELFPEGLRPALPEKHSSVKESFRYVNLTCSSGKQVPG 542
Query: 2066 EGGKCSSPK----------SRNHSKQECCCALKGEGWGDPCELCPTEP--DEAFRQICPY 2113
G+ S+PK N + C L C + TE +A R +
Sbjct: 543 APGRPSTPKEMFITVEFELETNQKEVTASCDLS-------CIVKRTEKRLRKAIRTLRKA 595
Query: 2114 GSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVG 2173
S +++D K+P Q + C G A N+CV C G
Sbjct: 596 VHREQFHLQLSGMNLDVAKKPPRTSERQAES--------CGVGQGHAENQCV---SCRAG 644
Query: 2174 N----------PCGNGTCKNVIGGFEC-TCEEGFEPGPMMTCE--DINECAQNPLLCAFR 2220
C NGT +N G C C G + T E +++EC LC
Sbjct: 645 TYYDGARERCILCPNGTFQNEEGQMTCEPCPRPGNSGALKTPEAWNMSECGG---LCQPG 701
Query: 2221 CVNTYGSYECK-CPVGYVLRE-DRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGP 2278
+ G C+ C +G E R C KH +C+ + C P
Sbjct: 702 EYSADGFAPCQLCALGTFQPEAGRTSCFPCGGGLATKHQGATSFQDCETRVQ-----CSP 756
Query: 2279 GYQRRPDGEGCV-----------DENECQTKPG-------------ICENGRCLNTRGSY 2314
G+ C+ +N C + PG C+N RC G +
Sbjct: 757 GHFYNTTTHRCIRCPVGTYQPEFGKNNCVSCPGNTTTDFDGSTNITQCKNRRCGGELGDF 816
Query: 2315 TCECNDGFTASPN 2327
T G+ SPN
Sbjct: 817 T-----GYIESPN 824
Score = 133 bits (335), Expect = 2e-30
Identities = 120/446 (26%), Positives = 168/446 (37%), Gaps = 121/446 (27%)
Query: 1280 DVNECDLNPNIC-LSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAV 1338
DV+EC + C C+NT S+ C C GY G+ + C DI+EC N G
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQ--CEDIDECG-NELNGGCVHD 101
Query: 1339 CTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY- 1395
C N G+++C+C G++ DG C D+DEC C QH C N MGSY C CKEG+
Sbjct: 102 CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC-QHT-CVNVMGSYECCCKEGFF 159
Query: 1396 -----------TGDGFTCTDLD-----------------ECSENLNLC------------ 1415
+ +G +C + D EC L
Sbjct: 160 LSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNH 219
Query: 1416 GNGQCLNA----PGGYRCECDMGFVPSADGKAC---ED---------------------- 1446
GNG C ++ G C C + DG++C ED
Sbjct: 220 GNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKR 279
Query: 1447 ---IDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCV 1503
++ C++ N TC + C C +G+ L G C D++EC C
Sbjct: 280 RLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCK 339
Query: 1504 NTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCC 1563
N GS+ C C F+L C D C LD D +C N G +C
Sbjct: 340 NIVGSFDCGCKKGFKLLTDEKSCQDV--DECSLD-----RTCDHSCINHPGT----FACA 388
Query: 1564 CSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCI 1623
C+ G Y + GF D +EC G CQ C+
Sbjct: 389 CNRG-----------------YTLY-----GFTH------CGDTNECSINNGGCQQ-VCV 419
Query: 1624 NTFGSFQCRCPTGYYLNEDTRVCDDV 1649
NT GS++C+C GY L+ + + C +V
Sbjct: 420 NTVGSYECQCHPGYKLHWNKKDCVEV 445
Score = 118 bits (295), Expect = 1e-25
Identities = 78/249 (31%), Positives = 113/249 (45%), Gaps = 21/249 (8%)
Query: 2512 PPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDEC 2571
PPG + D +EC ++ C + +CQNTP S+ C C+ G+ + G CED+DEC
Sbjct: 33 PPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGE--GRQCEDIDEC 90
Query: 2572 --EGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSY 2629
E N C H C NI G YRC+C G++ + + C+D +ECL + +C N +GSY
Sbjct: 91 GNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSY 150
Query: 2630 KCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSN-----TEGGYLCGCPPGY-FRIGQ 2683
+C C GF C +E G + +GCS+ G C C PG+ Q
Sbjct: 151 ECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQ 210
Query: 2684 GHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASNIED 2743
C+ G G DD + P EC + K RS E + + +E
Sbjct: 211 RDCILTCNHGNGG----CQHSCDDTADGP----ECSCHPQYKMHTDGRSCLEREDTVLE- 261
Query: 2744 QSETEANVS 2752
TE+N +
Sbjct: 262 --VTESNTT 268
Score = 105 bits (263), Expect = 5e-22
Identities = 62/191 (32%), Positives = 98/191 (51%), Gaps = 11/191 (5%)
Query: 465 CIPTPGSCRCECNKGFQLDLRGE-CIDVDECE-KNPCAGGECINNQGSYTCQCRAGYQST 522
C T C C GF L L G+ C D+DEC+ +N C N GS+ C C+ G++
Sbjct: 297 CKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLL 356
Query: 523 LTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMC 582
C+D+DEC + R C++ CIN G+F C CN G+ + +C D +ECSI N
Sbjct: 357 TDEKSCQDVDECSLD-RTCDHS-CINHPGTFACACNRGYTLY-GFTHCGDTNECSINNGG 413
Query: 583 LNGMCINEDGSFKCICKPGFQLASDGRYCKDIN----ECETPGICMN-GRCVNTDGSYRC 637
+C+N GS++C C PG++L + + C ++ +P + ++ G+ DG +
Sbjct: 414 CQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVSLHCGKSGGGDGCF-L 472
Query: 638 ECFPGLAVGLD 648
C G+ + D
Sbjct: 473 RCHSGIHLSSD 483
Score = 76.3 bits (186), Expect = 4e-13
Identities = 94/361 (26%), Positives = 134/361 (37%), Gaps = 67/361 (18%)
Query: 46 GGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPI--------CRHSCGDGFCSRP 97
GG HD L P Y C G+ G+ C+ C+H+C + S
Sbjct: 96 GGCVHDCLNIPG----NYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYE 151
Query: 98 NMCTCPSGQIAP----SCGSRSIQHCNIRCMNGG-SCSDDHCLCQKGYIGTHC------- 145
C C G +C RS + + CMN CS +G + C
Sbjct: 152 --CCCKEGFFLSDNQHTCIHRSEE--GLSCMNKDHGCSHICKEAPRGSVACECRPGFELA 207
Query: 146 -GQPVCESGCLNG-GRCVAPNRCACTYGFTGPQCE--------RDYRTGPCF----TVIS 191
Q C C +G G C + +C GP+C D R+ C TV+
Sbjct: 208 KNQRDCILTCNHGNGGC----QHSCDDTADGPECSCHPQYKMHTDGRS--CLEREDTVL- 260
Query: 192 NQMCQGQLSGIV-----CTKTLC---CATVGRAWGHPCEMCPAQPH-PCRRGFIPNIRTG 242
++ + + +V + L CA C+ H C GF +
Sbjct: 261 -EVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGK 319
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
C+D+DECQ G C C N VGSF+C C G KL + C+D+DECS + C+
Sbjct: 320 TCKDIDECQTRNGGCDHF-CKNIVGSFDCGCKKGFKLLTDEKSCQDVDECS-LDRTCD-H 376
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDA 362
C N ++ C C G YT T C D ++ NG C ++ +C C
Sbjct: 377 SCINHPGTFACACNRG-YTLYGFTHCGDTNE----CSINNGGCQQVCVNTVGSYECQCHP 431
Query: 363 G 363
G
Sbjct: 432 G 432
Score = 70.5 bits (171), Expect = 2e-11
Identities = 50/155 (32%), Positives = 68/155 (43%), Gaps = 12/155 (7%)
Query: 214 GRAWGHPCEMCPAQPHPCRRGFIPNIR---TGACQDVDEC-QAIPGLCQGGNCINTVGSF 269
G AW + P G +P R G +DVDEC Q + C NT S+
Sbjct: 10 GAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSY 69
Query: 270 ECKCPAGHKLNEVSQKCEDIDECST-IPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 328
+C C G++ ++CEDIDEC + G C +C N +Y C C GF + DG C
Sbjct: 70 KCSCKPGYQGE--GRQCEDIDECGNELNGGCVH-DCLNIPGNYRCTCFDGFMLAHDGHNC 126
Query: 329 IDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
+DV C NG C + + +CCC G
Sbjct: 127 LDV--DECLE--NNGGCQHTCVNVMGSYECCCKEG 157
Score = 62.0 bits (149), Expect = 8e-09
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 3/87 (3%)
Query: 244 CQDVDEC-QAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
C+D+DEC + G C +C+N G++ C C G L C D+DEC G C+
Sbjct: 84 CEDIDECGNELNGGCVH-DCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQ-H 141
Query: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCI 329
C N + SY C C GF+ S + CI
Sbjct: 142 TCVNVMGSYECCCKEGFFLSDNQHTCI 168
Score = 58.2 bits (139), Expect = 1e-07
Identities = 60/227 (26%), Positives = 89/227 (39%), Gaps = 17/227 (7%)
Query: 124 MNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRT 183
+N G C C+ G HC PV + L+G C + C G C+ +
Sbjct: 288 VNNGGCDRT---CKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGS 344
Query: 184 GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQ-PHPCRRGFIPNIRTG 242
C ++ + S C C+ + R H C P C RG+ T
Sbjct: 345 FDCGCKKGFKLLTDEKS---CQDVDECS-LDRTCDHSCINHPGTFACACNRGYTLYGFTH 400
Query: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID---ECSTIPGIC 299
C D +EC G CQ C+NTVGS+EC+C G+KL+ + C ++ S P +
Sbjct: 401 -CGDTNECSINNGGCQQV-CVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVS 458
Query: 300 EGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCS 346
+ F +C G + S D T +R + L G+CS
Sbjct: 459 LHCGKSGGGDGCFLRCHSGIHLSSDVT---TIRTSVTF-KLNEGKCS 501
Score = 43.5 bits (101), Expect = 0.003
Identities = 54/203 (26%), Positives = 72/203 (35%), Gaps = 29/203 (14%)
Query: 2015 DECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPK 2074
++CV C GT + LCP G + G+ + C G +P+
Sbjct: 636 NQCVS----CRAGTYYDGARERCILCPNGTFQNEEGQ----MTCEPCPRPGNSGALKTPE 687
Query: 2075 SRNHSKQECCCALKGEGWGD---PCELCP--TEPDEAFRQIC-PYGSGIIVGPDDSAVDM 2128
+ N S+ C GE D PC+LC T EA R C P G G+ A
Sbjct: 688 AWNMSECGGLCQ-PGEYSADGFAPCQLCALGTFQPEAGRTSCFPCGGGLAT-KHQGATSF 745
Query: 2129 DECKEPDVCKHGQCINTDGSYRC-ECPFG-----------YILAGNECVDTDECSVGNPC 2176
+C+ C G NT ++RC CP G GN D D + C
Sbjct: 746 QDCETRVQCSPGHFYNTT-THRCIRCPVGTYQPEFGKNNCVSCPGNTTTDFDGSTNITQC 804
Query: 2177 GNGTCKNVIGGFECTCEEGFEPG 2199
N C +G F E PG
Sbjct: 805 KNRRCGGELGDFTGYIESPNYPG 827
Score = 37.4 bits (85), Expect = 0.22
Identities = 49/165 (29%), Positives = 54/165 (32%), Gaps = 50/165 (30%)
Query: 1574 CEMCP------------AVNTSEYKILCPGGE----GFRPNPITVILEDIDECQELPGLC 1617
CE CP A N SE LC GE GF P CQ LC
Sbjct: 671 CEPCPRPGNSGALKTPEAWNMSECGGLCQPGEYSADGFAP------------CQ----LC 714
Query: 1618 QGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICP-P 1676
G G C P G L + +CET C PG YNT + CP
Sbjct: 715 ALGTFQPEAGRTSC-FPCGGGLATKHQGATSFQDCETRVQCSPGHFYNTTTHRCIRCPVG 773
Query: 1677 DYMQVNGGNNCMDMRRSLCYRNYYAD-----------NQTCDGEL 1710
Y G NNC+ C N D N+ C GEL
Sbjct: 774 TYQPEFGKNNCVS-----CPGNTTTDFDGSTNITQCKNRRCGGEL 813
Score = 32.0 bits (71), Expect = 9.0
Identities = 58/255 (22%), Positives = 87/255 (34%), Gaps = 48/255 (18%)
Query: 997 PMRNTPEYEELCPRGPGFATKEITNGKP--FFKDINECKMIPSLCTHGKCRNTIGSFKCR 1054
P R + E C G G A + + + ++ E + LC +G +N G C
Sbjct: 616 PPRTSERQAESCGVGQGHAENQCVSCRAGTYYDGARERCI---LCPNGTFQNEEGQMTCE 672
Query: 1055 -C----DSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMK 1109
C +SG E N ++ CG G C PG++ +G+ +
Sbjct: 673 PCPRPGNSGALKTPEAWNMSE----------CG-GLC--QPGEYSA---DGFAPCQLCAL 716
Query: 1110 NCMDIDECQRDPLLCRGGVCHNTEGSY-------RCECPPGHQLSPNISACIDINECELS 1162
+ + C GG+ +G+ R +C PGH + CI
Sbjct: 717 GTFQPEAGRTSCFPCGGGLATKHQGATSFQDCETRVQCSPGHFYNTTTHRCI-------- 768
Query: 1163 AHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECS 1222
CP G GK C PG ++T D +I +C N C + G E
Sbjct: 769 --RCPVGTYQPEFGKNNCVSCPG-NTTTDFDGSTNITQCK--NRRCGGELGDFTGYIESP 823
Query: 1223 CQPGFALMPDQRSCT 1237
PG P CT
Sbjct: 824 NYPG--NYPANTECT 836
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 220 bits (560), Expect = 2e-56
Identities = 137/399 (34%), Positives = 195/399 (48%), Gaps = 36/399 (9%)
Query: 1070 DIDECRISPDLCGRGQ-CVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGV 1128
D+DEC D C C NTP ++C C GY K+C D+DEC+R+
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDG---KHCKDVDECEREDNAGCVHD 85
Query: 1129 CHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHS 1188
C N G+YRC C G L+ + C+D++EC C CVN++G Y+C C G+
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFL 144
Query: 1189 TPDRLFCVDIDE----CSIMNGGCETFCTNS-EGSYECSCQPGFALMPDQRSCTDIDECE 1243
+ ++ C+ E C N GC C + +G C C+PGF L +QR +C+
Sbjct: 145 SDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQR------DCK 198
Query: 1244 DNPNICDGG---QCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTK 1300
N +GG C + RC C+ F+ D KTC++ C +N C S C +
Sbjct: 199 LTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGCDS-KCHDAA 255
Query: 1301 GSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDG 1358
C C +G+ + + C DI+EC + +N G +C NT GSF+CSC G+ + +
Sbjct: 256 TGVHCTCPVGFMLQPDRKTCKDIDECRL--NNGGCDHICRNTVGSFECSCKKGYKLLINE 313
Query: 1359 IKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFT-CTDLDECSENLNLCGN 1417
C D+DECS C C NT GS++CLC GY G T C D+DECS N C
Sbjct: 314 RNCQDIDECSFD-RTCDHI--CVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRF 370
Query: 1418 GQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNIC 1456
G C+N PG Y+C C P+ G+ + +C+ P C
Sbjct: 371 G-CINTPGSYQCTC-----PAGQGRLHWNGKDCTEPLKC 403
Score = 218 bits (555), Expect = 7e-56
Identities = 142/405 (35%), Positives = 187/405 (46%), Gaps = 30/405 (7%)
Query: 1027 KDINECKMIPSLC-THGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ 1085
+D++EC C C+NT S+KC C SG+ D ++C D+DEC +
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDG--KHCKDVDECEREDNAGCVHD 85
Query: 1086 CVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQ 1145
CVN PG++ C C +G+ NC+D+DEC C+ C N GSY C C G
Sbjct: 86 CVNIPGNYRCTCYDGFHLAH-DGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFF 143
Query: 1146 LSPNISACIDINE----CELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC 1201
LS N CI E C H C + G C C PG+ T ++ C C
Sbjct: 144 LSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCK--LTC 201
Query: 1202 SIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1261
+ NGGC+ C ++E C C F L D ++C I+ C N CD +C +
Sbjct: 202 NYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGCD-SKCHDAATGV 258
Query: 1262 RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321
C C GFM D KTC D++EC LN C C NT GSF C C GY + C
Sbjct: 259 HCTCPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINERNCQ 317
Query: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGI-KCTDLDECSNGTHMCSQHADC 1380
DI+EC C +C NT GSF+C C G++ GI C D+DECS C C
Sbjct: 318 DIDECSFD-RTCDH--ICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGC--RFGC 372
Query: 1381 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPG 1425
NT GSY+C C G G + +C+E L +C +PG
Sbjct: 373 INTPGSYQCTCP---AGQGRLHWNGKDCTEPL------KCQGSPG 408
Score = 198 bits (504), Expect = 6e-50
Identities = 130/375 (34%), Positives = 171/375 (45%), Gaps = 28/375 (7%)
Query: 1152 ACIDINECELSAHLCP-NGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIM-NGGCE 1209
A D++EC C + C N Y+C C GY T D C D+DEC N GC
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCV 83
Query: 1210 TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF 1269
C N G+Y C+C GF L D +C D+DEC + C C N+ G Y C C +GF
Sbjct: 84 HDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGF 142
Query: 1270 MASEDMKTCVDVNE----CDLNPNICLSGTCENT-KGSFICHCDMGYSGKKGKTGCTDIN 1324
S++ TC+ E C +N N + C T KG C C G+ K + C
Sbjct: 143 FLSDNQHTCIQRPEEGMNC-MNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCK--L 199
Query: 1325 ECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKN 1382
C G N G C +T +C C ++ DG C + +NG C + C +
Sbjct: 200 TCNYG--NGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGG--CD--SKCHD 253
Query: 1383 TMGSYRCLCKEGYT--GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD 1440
C C G+ D TC D+DEC N C + C N G + C C G+ +
Sbjct: 254 AATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKLLIN 312
Query: 1441 GKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCIS 1499
+ C+DIDECS C C N PG F+C C GY L +C DV+EC ++ C
Sbjct: 313 ERNCQDIDECSFDRTCDH-ICVNTPGSFQCLCHRGYLL-YGITHCGDVDECSINRGGCRF 370
Query: 1500 GNCVNTPGSYICDCP 1514
G C+NTPGSY C CP
Sbjct: 371 G-CINTPGSYQCTCP 384
Score = 198 bits (504), Expect = 6e-50
Identities = 132/405 (32%), Positives = 181/405 (44%), Gaps = 61/405 (15%)
Query: 2205 EDINECAQNPLLCAFR--CVNTYGSYECKCPVGYVLREDRRMCKDEDECE-EGKHDCTEK 2261
+D++EC + C C NT SY+C C GY D + CKD DECE E C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECEREDNAGCVH- 84
Query: 2262 QMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDG 2321
+C N+ G Y C C G+ DG C+D +EC G C+ C+N GSY C C +G
Sbjct: 85 --DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREG 141
Query: 2322 FTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECC---CDGGRGWGPHCEIC 2378
F S NQ C+ E N + K+ C C G CE
Sbjct: 142 FFLSDNQHTCIQRPE----------------EGMNCMNKNHGCAHICRETPKGGIACECR 185
Query: 2379 P-FQGTVA---FKKLCPHGRGFMTNGAD-----------------------IDECKVIHD 2411
P F+ T K C +G G + D I+ C V +
Sbjct: 186 PGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNG 245
Query: 2412 VCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCP 2471
C + +C + HC C G+ +C D++EC C+ IC+NT GS++CSC
Sbjct: 246 GC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCK 304
Query: 2472 KGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHH-TSCIDNNECTS 2530
KGY L + R+C+D+DEC+ C +CVNT G F C C G+ + T C D +EC+
Sbjct: 305 KGYKLLINERNCQDIDECSF-DRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECS- 362
Query: 2531 DINLCGSKGICQNTPGSFTCECQRGFS-LDQTGSSCEDVDECEGN 2574
IN G + C NTPGS+ C C G L G C + +C+G+
Sbjct: 363 -INRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGS 406
Score = 198 bits (503), Expect = 7e-50
Identities = 140/414 (33%), Positives = 184/414 (44%), Gaps = 54/414 (13%)
Query: 1918 HGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINEC 1977
H ++ DVDEC G N + C NT S++C C GY DG+ C D++EC
Sbjct: 17 HARAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDEC 74
Query: 1978 LLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTCSNTEGS 2035
E C N+ G+YRC C G+ L ++ C D+DEC E C +C N GS
Sbjct: 75 EREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQ-QSCVNMMGS 133
Query: 2036 FKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCAL-KGEGWGD 2094
++C C EGF LS + C EG C ++NH C KG G
Sbjct: 134 YECHCREGFFLSDNQHTC-------IQRPEEGMNC---MNKNHGCAHICRETPKG---GI 180
Query: 2095 PCELCP----TEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYR 2150
CE P T+ + C YG+G C+H C +T+ R
Sbjct: 181 ACECRPGFELTKNQRDCKLTCNYGNG-------------------GCQH-TCDDTEQGPR 220
Query: 2151 CECPFGYIL--AGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGP-MMTCEDI 2207
C C ++L G C++T C+V N + C + G CTC GF P TC+DI
Sbjct: 221 CGCHIKFVLHTDGKTCIET--CAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDI 278
Query: 2208 NECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKN 2267
+EC N C C NT GS+EC C GY L + R C+D DEC D T + C N
Sbjct: 279 DECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDEC---SFDRTCDHI-CVN 334
Query: 2268 LIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDG 2321
G++ C+C GY C D +EC G C G C+NT GSY C C G
Sbjct: 335 TPGSFQCLCHRGYLLYGITH-CGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 192 bits (489), Expect = 3e-48
Identities = 143/499 (28%), Positives = 206/499 (41%), Gaps = 56/499 (11%)
Query: 2243 RMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC 2302
+ +D DEC EG +C + C+N +Y CIC GY DG+ C D +EC+ +
Sbjct: 25 KAAQDVDECVEGTDNCHIDAI-CQNTPRSYKCICKSGYTG--DGKHCKDVDECEREDNAG 81
Query: 2303 ENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSE 2362
C+N G+Y C C DGF + + CLD E Q C N + E
Sbjct: 82 CVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCV------NMMGSYE 135
Query: 2363 CCCDGGRGWGPHCEIC---PFQGTVAFKKL--CPHGRGFMTNGADIDECKVIHDVCRNGE 2417
C C G + C P +G K C H +CR
Sbjct: 136 CHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAH-------------------ICRE-- 174
Query: 2418 CVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQ 2477
+G C C+ G+ C CN C C +TE +C C ++L
Sbjct: 175 --TPKGGIACECRPGFELTKNQRDCK--LTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLH 230
Query: 2478 EDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQH--HTSCIDNNECTSDINLC 2535
DG++C ++ CA C C + G C CP GF +C D +EC +N
Sbjct: 231 TDGKTC--IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECR--LNNG 286
Query: 2536 GSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQG 2595
G IC+NT GSF C C++G+ L +C+D+DEC + C H C N G ++C C +G
Sbjct: 287 GCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHICVNTPGSFQCLCHRG 346
Query: 2596 YLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSG-GCQDINEC-- 2652
YL Y C D +EC C NT GSY+C CPAG ++G C + +C
Sbjct: 347 YLL-YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQG 405
Query: 2653 --GSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEP---PVSGEMDD 2707
G+++A S S + CP + + +G + G P P P +
Sbjct: 406 SPGASKAMLSCNRSGKKDTCALTCPSRARFLPESE--NGFTVSCGTPSPRAAPARAGHNG 463
Query: 2708 NSLSPEACYECKINGYPKR 2726
NS + C+E + +R
Sbjct: 464 NSTNSNHCHEAAVLSIKQR 482
Score = 186 bits (471), Expect = 4e-46
Identities = 135/417 (32%), Positives = 193/417 (46%), Gaps = 80/417 (19%)
Query: 989 GTEECE-ECPMRNTPE-YEELCPRGPGFATKEITNGKPFFKDINECKMIPSL-CTHGKCR 1045
GT+ C + +NTP Y+ +C G T KD++EC+ + C H C
Sbjct: 36 GTDNCHIDAICQNTPRSYKCICKSG-------YTGDGKHCKDVDECEREDNAGCVHD-CV 87
Query: 1046 NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGY---- 1101
N G+++C C GF L + NC D+DEC C + CVN G +EC C EG+
Sbjct: 88 NIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLSD 146
Query: 1102 ---------ESGFMMMKNCMDID-----------------EC---------QRD-PLLCR 1125
E G NCM+ + EC QRD L C
Sbjct: 147 NQHTCIQRPEEGM----NCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN 202
Query: 1126 GG------VCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQ 1179
G C +TE RC C L + CI+ C ++ C + +C +
Sbjct: 203 YGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIET--CAVNNGGC-DSKCHDAATGVH 259
Query: 1180 CACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDI 1239
C C G+ PDR C DIDEC + NGGC+ C N+ GS+ECSC+ G+ L+ ++R+C DI
Sbjct: 260 CTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 1240 DECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENT 1299
DEC + CD C N PG ++CLC+ G++ + C DV+EC +N C G C NT
Sbjct: 320 DECSFD-RTCD-HICVNTPGSFQCLCHRGYLL-YGITHCGDVDECSINRGGCRFG-CINT 375
Query: 1300 KGSFICHCDMG-----YSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCS 1351
GS+ C C G ++GK CT+ +C+ G+ K + N +G K +C+
Sbjct: 376 PGSYQCTCPAGQGRLHWNGK----DCTEPLKCQ-GSPGASKAMLSCNRSGK-KDTCA 426
Score = 179 bits (454), Expect = 4e-44
Identities = 113/336 (33%), Positives = 151/336 (44%), Gaps = 14/336 (4%)
Query: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLN 1422
D+DEC GT C A C+NT SY+C+CK GYTGDG C D+DEC N C+N
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVN 88
Query: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSG 1482
PG YRC C GF + DG C D+DEC+ N +C N+ G + C C G+ L +
Sbjct: 89 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQ 148
Query: 1483 GNCTDVNE----CLDPTTCISGNCVNTP-GSYICDCPPDFELNPTRVGCVDT---RSGNC 1534
C E C++ + C TP G C+C P FEL + C T +G C
Sbjct: 149 HTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGC 208
Query: 1535 YLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEG 1594
C + + +C + G C T + C G
Sbjct: 209 QHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATG---VHCTCPVG 265
Query: 1595 FRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET 1654
F P +DIDEC+ G C C NT GSF+C C GY L + R C D++EC
Sbjct: 266 FMLQPDRKTCKDIDECRLNNGGCD-HICRNTVGSFECSCKKGYKLLINERNCQDIDECSF 324
Query: 1655 PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
C C NT G++ C+C Y+ + G +C D+
Sbjct: 325 DRTC-DHICVNTPGSFQCLCHRGYL-LYGITHCGDV 358
Score = 174 bits (440), Expect = 1e-42
Identities = 130/415 (31%), Positives = 184/415 (44%), Gaps = 47/415 (11%)
Query: 490 DVDECEK---NPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRC 546
DVDEC + N C N SY C C++GY T C+D+DEC + C
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCVHDC 86
Query: 547 INTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLAS 606
+N G++ C C GFH+ DG NC D+DEC+ N C+N GS++C C+ GF L+
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSD 146
Query: 607 DGRYCKDINECETPGICMNGR------CVNT-DGSYRCECFPGLAVGLDGRVCVDTHMRS 659
+ C I E CMN C T G CEC PG + + R C +
Sbjct: 147 NQHTC--IQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDC-----KL 199
Query: 660 TCYGGYKRGQCIKPLFGAVTKSECCC--ASTEYAFGEPCQPCPAQNSAEYQALC---SSG 714
TC Y G C C C + G+ C A N+ + C ++G
Sbjct: 200 TC--NYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATG 257
Query: 715 PGMT-----------SAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 763
T DI+EC L+ C + IC N G+++C C GY++ +NC
Sbjct: 258 VHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKLLINERNC 316
Query: 764 VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC--ESSPCINGVC 821
DI+EC + CD+ C NTPGSF C C +G++ + C D+DEC C G C
Sbjct: 317 QDIDECSFDR-TCDH-ICVNTPGSFQCLCHRGYLLY-GITHCGDVDECSINRGGCRFG-C 372
Query: 822 KNSPGSFICEC-SSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC 875
N+PGS+ C C + + L C E +K C + + ++ N + K C
Sbjct: 373 INTPGSYQCTCPAGQGRLHWNGKDCTEPLK--CQGSPGASKAMLSCNRSGKKDTC 425
Score = 169 bits (428), Expect = 4e-41
Identities = 129/434 (29%), Positives = 186/434 (42%), Gaps = 53/434 (12%)
Query: 529 RDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNM--CLNG 585
+D+DEC++ C+ + C NT S+ C+C +G+ T DGK+C+D+DEC + C++
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCVHD 85
Query: 586 MCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNGRCVNTDGSYRCECFPGLA 644
C+N G+++C C GF LA DG C D++EC E G C CVN GSY C C G
Sbjct: 86 -CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFF 143
Query: 645 VGLDGRVCVD---------------THM-RSTCYGGYKRGQCIKPLFGAVTKSECCCAST 688
+ + C+ H+ R T GG +C +P F C +
Sbjct: 144 LSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIAC-EC-RPGFELTKNQRDCKLTC 201
Query: 689 EYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKC 748
Y G C T + I CA++ C + + G + C
Sbjct: 202 NYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVH-C 260
Query: 749 ICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDI 808
C G+ + K C DI+EC LN+ CD+ CRNT GSF C+C KG+ + + C+DI
Sbjct: 261 TCPVGFMLQPDRKTCKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKLLINERNCQDI 319
Query: 809 DECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEINING 868
DEC + +C N+PGSF C C L T C + C IN G
Sbjct: 320 DECSFDRTCDHICVNTPGSFQCLCHRGYLLYGI-THCGDV-----------DECSINRGG 367
Query: 869 ATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVN 928
C + ++ C G+G G C + +C+ PG K L N
Sbjct: 368 CRFG---CINTPGSYQCTCP-------AGQGRLHWNGKDCTEPLKCQGSPGASKAMLSCN 417
Query: 929 TRG---SFKCQCPS 939
G + CPS
Sbjct: 418 RSGKKDTCALTCPS 431
Score = 156 bits (395), Expect = 2e-37
Identities = 140/523 (26%), Positives = 205/523 (39%), Gaps = 86/523 (16%)
Query: 447 VNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAG--GEC 504
V TD C + +CQN TP S +C C G+ D + C DVDECE+ AG +C
Sbjct: 34 VEGTDNCH-IDAICQN-----TPRSYKCICKSGYTGDGK-HCKDVDECEREDNAGCVHDC 86
Query: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
+N G+Y C C G+ C D+DEC + C C+N GS+ C C GF ++
Sbjct: 87 VNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-CVNMMGSYECHCREGFFLS 145
Query: 565 RDGKNCEDMDECSIRNMCLNGMCIN-----EDGSFKCICKPGFQLASDGRYCKDINECET 619
+ C E + M N C + G C C+PGF+L + R CK
Sbjct: 146 DNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGN 205
Query: 620 PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVT 679
G C + C +T+ RC C + DG+ C++T C G C A T
Sbjct: 206 GG-CQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIET-----C--AVNNGGCDSKCHDAAT 256
Query: 680 KSECCCA-----STEYAFGEPCQPCPAQNSA----------EYQALCSSGPGMTSAG--- 721
C C + + C N ++ C G +
Sbjct: 257 GVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNC 316
Query: 722 SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQC 781
DI+EC+ D + IC N G+++C+C+ GY + +C D++EC +N C G C
Sbjct: 317 QDIDECSFDRTC--DHICVNTPGSFQCLCHRGYLLYGI-THCGDVDECSINRGGCRFG-C 372
Query: 782 RNTPGSFVCTCPKGF-IYKPDLKTCEDIDECESSPCINGV---CKNSPGSFICE--CSSE 835
NTPGS+ CTCP G + K C + +C+ SP + C S C C S
Sbjct: 373 INTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAMLSCNRSGKKDTCALTCPSR 432
Query: 836 STLDPTKTICIETIKGT---------------------CWQTVI------------DGRC 862
+ P GT C + + D +C
Sbjct: 433 ARFLPESENGFTVSCGTPSPRAAPARAGHNGNSTNSNHCHEAAVLSIKQRASFKIKDAKC 492
Query: 863 EININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKG 905
+++ K++ + G+PC+ CQV I K S KG
Sbjct: 493 RLHLRNKG-KTEEAGRITGPGGAPCSECQVTFIHLKCDSSRKG 534
Score = 154 bits (390), Expect = 9e-37
Identities = 123/402 (30%), Positives = 174/402 (43%), Gaps = 40/402 (9%)
Query: 1605 EDIDECQELPGLCQ-GGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICG-PGT 1662
+D+DEC E C C NT S++C C +GY D + C DV+ECE G
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDVDECEREDNAGCVHD 85
Query: 1663 CYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCS 1722
C N GNY C C + + G+NC+D+ N C + M C C
Sbjct: 86 CVNIPGNYRCTCYDGFHLAHDGHNCLDVDECA------EGNGGCQQSCVNMMGSYECHCR 139
Query: 1723 YNIGRAWNK-PCEQCP------IPSTDEFATLCG-SQRPGFVIDIYTGLPVDIDE----- 1769
+ N+ C Q P + A +C + + G + G + ++
Sbjct: 140 EGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKL 199
Query: 1770 -CREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTA 1828
C G C++ C + RC C + F + C + NG +++C + A
Sbjct: 200 TCNYGNGGCQH-TCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGC---DSKCHDAA 255
Query: 1829 GSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQT 1887
C C G+ + C D +EC+ C H C +TVGSF C C G+K ++
Sbjct: 256 TGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH-ICRNTVGSFECSCKKGYKLLINER 314
Query: 1888 MCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQC 1947
C DI+EC D + C NT GSF C C+ G++L C DVDEC+ G CR G C
Sbjct: 315 NCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGG-CRFG-C 372
Query: 1948 INTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC--APG 1987
INT GS+QC C G GR + +C EP KC +PG
Sbjct: 373 INTPGSYQCTCPAG-----QGRLHWNGKDC-TEPLKCQGSPG 408
Score = 144 bits (362), Expect = 2e-33
Identities = 122/404 (30%), Positives = 176/404 (43%), Gaps = 48/404 (11%)
Query: 909 EDIDECEVFPGVCK-NGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC 967
+D+DEC C + +C NT S+KC C SG T D G+ C D+ + C R ++ C
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGD--GKHCKDV--DEC-EREDNAGC 82
Query: 968 T---LPIAGRHRMDACCCSVG---------------AAWGTEECEECPMRNTPEYEELCP 1009
+ I G +R C C G A G C++ + YE C
Sbjct: 83 VHDCVNIPGNYR---CTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCR 139
Query: 1010 RGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNT-IGSFKCRCDSGFALDSEERNC 1068
G + + T + + +N C C H CR T G C C GF L +R
Sbjct: 140 EGFFLSDNQHTCIQRPEEGMN-CMNKNHGCAH-ICRETPKGGIACECRPGFELTKNQR-- 195
Query: 1069 TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMM---KNCMDIDECQRDPLLCR 1125
+C+++ + G G C +T D E G F++ K C I+ C + C
Sbjct: 196 ----DCKLTCNY-GNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTC--IETCAVNNGGC- 247
Query: 1126 GGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPG 1185
CH+ C CP G L P+ C DI+EC L+ C + C N +G ++C+C G
Sbjct: 248 DSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH-ICRNTVGSFECSCKKG 306
Query: 1186 YHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDN 1245
Y + C DIDECS + C+ C N+ GS++C C G+ L+ C D+DEC N
Sbjct: 307 YKLLINERNCQDIDECS-FDRTCDHICVNTPGSFQCLCHRGY-LLYGITHCGDVDECSIN 364
Query: 1246 PNICDGGQCTNIPGEYRCLCYDG-FMASEDMKTCVDVNECDLNP 1288
C G C N PG Y+C C G + K C + +C +P
Sbjct: 365 RGGCRFG-CINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSP 407
Score = 126 bits (316), Expect = 4e-28
Identities = 106/354 (29%), Positives = 145/354 (40%), Gaps = 69/354 (19%)
Query: 889 LCQVDP-----ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTL 943
+CQ P IC GY+ G C+D+DECE CVN G+++C C G L
Sbjct: 45 ICQNTPRSYKCICKSGYTG-DGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHL 103
Query: 944 DATGRICLDIR---------LETCFLRYEDEEC----------------TLPIAGRHRMD 978
G CLD+ ++C EC P G + M+
Sbjct: 104 AHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMN 163
Query: 979 -----------------ACCCSVGAAWGTEECEECPM---------RNTPEYEELCPR-G 1011
AC C G T+ +C + ++T + E PR G
Sbjct: 164 KNHGCAHICRETPKGGIACECRPGFEL-TKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCG 222
Query: 1012 PGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDI 1071
T+GK I C + C KC + C C GF L + + C DI
Sbjct: 223 CHIKFVLHTDGKTC---IETCAVNNGGC-DSKCHDAATGVHCTCPVGFMLQPDRKTCKDI 278
Query: 1072 DECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHN 1131
DECR++ C C NT G FEC C +GY+ + +NC DIDEC D +C N
Sbjct: 279 DECRLNNGGCDH-ICRNTVGSFECSCKKGYKL-LINERNCQDIDECSFDRTC--DHICVN 334
Query: 1132 TEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPG 1185
T GS++C C G+ L I+ C D++EC ++ C G C+N G YQC C G
Sbjct: 335 TPGSFQCLCHRGYLLY-GITHCGDVDECSINRGGCRFG-CINTPGSYQCTCPAG 386
Score = 115 bits (287), Expect = 8e-25
Identities = 61/169 (36%), Positives = 86/169 (50%), Gaps = 9/169 (5%)
Query: 2517 QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDEC--EGN 2574
Q+ + D +EC + C ICQNTP S+ C C+ G++ D G C+DVDEC E N
Sbjct: 22 QYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGD--GKHCKDVDECEREDN 79
Query: 2575 HRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCP 2634
C H C NI G YRC+C G+ + + C+D +EC + SC N +GSY+C C
Sbjct: 80 AGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCR 139
Query: 2635 AGFQYEQFSGGC----QDINECGSAQAPCSYGCSNT-EGGYLCGCPPGY 2678
GF C ++ C + C++ C T +GG C C PG+
Sbjct: 140 EGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGF 188
Score = 87.0 bits (214), Expect = 2e-16
Identities = 98/341 (28%), Positives = 129/341 (37%), Gaps = 38/341 (11%)
Query: 46 GGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGF-CSRPNMCTCPS 104
G G H K + C NA C +PG +C H DG C + C +
Sbjct: 63 GDGKH--CKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGN 120
Query: 105 GQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLC-QKGYIGTHCGQPVCESGCLNGGRCVAP 163
G SC + + C G SD+ C Q+ G +C GC + R
Sbjct: 121 GGCQQSCVNMMGSY-ECHCREGFFLSDNQHTCIQRPEEGMNCMNK--NHGCAHICRETPK 177
Query: 164 N--RCACTYGFTGPQCERD------YRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGR 215
C C GF + +RD Y G C + QG G C T G+
Sbjct: 178 GGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTE-QGPRCG--CHIKFVLHTDGK 234
Query: 216 AWGHPCEM----CPAQPHP--------CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCI 263
C + C ++ H C GF+ C+D+DEC+ G C C
Sbjct: 235 TCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH-ICR 293
Query: 264 NTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSP 323
NTVGSFEC C G+KL + C+DIDECS C+ C NT S+ C C G Y
Sbjct: 294 NTVGSFECSCKKGYKLLINERNCQDIDECS-FDRTCD-HICVNTPGSFQCLCHRG-YLLY 350
Query: 324 DGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGR 364
T C DV ++ G C + QC C AG+
Sbjct: 351 GITHCGDVDE----CSINRGGCRFGCINTPGSYQCTCPAGQ 387
Score = 64.7 bits (156), Expect = 1e-09
Identities = 39/122 (31%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 243 ACQDVDECQAIPGLCQ-GGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG 301
A QDVDEC C C NT S++C C +G+ + + C+D+DEC
Sbjct: 26 AAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGD--GKHCKDVDECEREDNAGCV 83
Query: 302 GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCD 361
+C N +Y C C GF+ + DG C+DV A NG C + +C C
Sbjct: 84 HDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDE----CAEGNGGCQQSCVNMMGSYECHCR 139
Query: 362 AG 363
G
Sbjct: 140 EG 141
Score = 51.6 bits (122), Expect = 1e-05
Identities = 43/168 (25%), Positives = 56/168 (33%), Gaps = 50/168 (29%)
Query: 244 CQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDE------------ 291
C DVDEC G CQ +C+N +GS+EC C G L++ C E
Sbjct: 110 CLDVDECAEGNGGCQQ-SCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGC 168
Query: 292 -------------CSTIPGI------------CEGGE------CTNTVSSYFCKCPPGFY 320
C PG C G C +T C C F
Sbjct: 169 AHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFV 228
Query: 321 TSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSP 368
DG CI+ A+ NG C ++ + T + C C G P
Sbjct: 229 LHTDGKTCIET------CAVNNGGCDSKCHDAATGVHCTCPVGFMLQP 270
Score = 42.4 bits (98), Expect = 0.007
Identities = 62/234 (26%), Positives = 81/234 (34%), Gaps = 54/234 (23%)
Query: 1984 CAPGTCQNLDGSYRCICPPG--YSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKC-LC 2040
C PG Q+ G+ CP G Y Q E+C C GT EG C LC
Sbjct: 625 CRPG--QHRAGTKCVSCPQGTYYHGQTEQCVP----------CPAGTFQEREGQLSCDLC 672
Query: 2041 PEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCP 2100
P + G ++ C G+C + HS +G+ PC+ CP
Sbjct: 673 PGSDAHGPLGAT----NVTTC-----AGQCPPGQ---HSV---------DGF-KPCQPCP 710
Query: 2101 --TEPDEAFRQIC-PYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRC-ECPFG 2156
T EA R +C P G G+ + A+ +C C G NT +RC C G
Sbjct: 711 RGTYQPEAGRTLCFPCGGGLTT-KHEGAISFQDCDTKVQCSPGHYYNT-SIHRCIRCAMG 768
Query: 2157 YI-----------LAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPG 2199
GN D D + C N C +G F E PG
Sbjct: 769 SYQPDFRQNFCSRCPGNTSTDFDGSTSVAQCKNRQCGGELGEFTGYIESPNYPG 822
Score = 39.3 bits (90), Expect = 0.057
Identities = 36/125 (28%), Positives = 44/125 (35%), Gaps = 22/125 (17%)
Query: 2562 GSSCEDVDECE-GNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCV--------DENECL 2612
G E ++ C G HR C SCPQG H Q QCV + L
Sbjct: 616 GERAEPMESCRPGQHRAGTKC--------VSCPQGTYYHGQTEQCVPCPAGTFQEREGQL 667
Query: 2613 SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLC 2672
S +C G+ H LG+ AG Q G ++ Q PC G E G
Sbjct: 668 SCDLCPGSDAHGPLGATNVTTCAG----QCPPGQHSVDGFKPCQ-PCPRGTYQPEAGRTL 722
Query: 2673 GCPPG 2677
P G
Sbjct: 723 CFPCG 727
Score = 33.9 bits (76), Expect = 2.4
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Query: 281 EVSQKCEDIDECSTIPGICE-GGECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331
+ S+ +D+DEC C C NT SY C C G+ + DG C DV
Sbjct: 22 QYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGY--TGDGKHCKDV 71
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 217 bits (552), Expect = 2e-55
Identities = 135/407 (33%), Positives = 192/407 (47%), Gaps = 32/407 (7%)
Query: 1100 GYESGFMMMKNCMDIDECQRDPLLCR-GGVCHNTEGSYRCECPPGHQLSPNISACIDINE 1158
G +G + +D+DEC C +C NT SY+C C PG++ C DI+E
Sbjct: 20 GRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGK--QCEDIDE 77
Query: 1159 CELSAHLCPNG----RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTN 1214
CE + NG C+N+ G Y+C C G+ D C+D+DEC NGGC+ C N
Sbjct: 78 CENDYY---NGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVN 134
Query: 1215 SEGSYECSCQPGFALMPDQRSC----TDIDECEDNPNICDGGQCTNIP-GEYRCLCYDGF 1269
+ GSYEC C GF L +Q +C + C + + C C P G C C GF
Sbjct: 135 AMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGC-AHICRETPKGGVACDCRPGF 193
Query: 1270 MASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIG 1329
+++ K C C+ C +CE+T C C Y+ G T I C +
Sbjct: 194 DLAQNQKDC--TLTCNYGNGGC-QHSCEDTDTGPTCGCHQKYA--LHSDGRTCIETCAVN 248
Query: 1330 AHNCGKHAVCTNTAGSFKCSCSPGWI--GDGIKCTDLDECSNGTHMCSQHADCKNTMGSY 1387
C + C +TA +CSC G+ DG C D++EC C C+NT+GS+
Sbjct: 249 NGGCDR--TCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHF--CRNTVGSF 304
Query: 1388 RCLCKEGY--TGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE 1445
C C++GY D TC D+DECS C + C+N+PG ++C C G++ C
Sbjct: 305 ECGCRKGYKLLTDERTCQDIDECSFE-RTCDH-ICINSPGSFQCLCHRGYILYGT-THCG 361
Query: 1446 DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECL 1492
D+DECS+ N C N G + C C G L +G +C + +CL
Sbjct: 362 DVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCL 408
Score = 202 bits (513), Expect = 5e-51
Identities = 132/443 (29%), Positives = 184/443 (41%), Gaps = 54/443 (12%)
Query: 2247 DEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTK--PGICEN 2304
D DEC EG DC + C+N +Y C+C PGY + +G+ C D +EC+ G C +
Sbjct: 33 DVDECSEGTDDCHIDAI-CQNTPKSYKCLCKPGY--KGEGKQCEDIDECENDYYNGGCVH 89
Query: 2305 GRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECC 2364
C+N G+Y C C DGF + + CLD E Q +C N + EC
Sbjct: 90 -ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICV------NAMGSYECQ 142
Query: 2365 CDGGRGWGPHCEICPFQGTVAFKKL-----CPHGRGFMTNGADIDECKVIHDVCRNGECV 2419
C G + C + + C H +CR
Sbjct: 143 CHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH-------------------ICRE---- 179
Query: 2420 NDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQED 2479
+G C C+ G+ C CN C C++T+ C C + Y L D
Sbjct: 180 TPKGGVACDCRPGFDLAQNQKDCT--LTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSD 237
Query: 2480 GRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHT--SCIDNNECTSDINLCGS 2537
GR+C ++ CA C C +T G C CP GFT +C D NEC +N G
Sbjct: 238 GRTC--IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECL--VNNGGC 293
Query: 2538 KGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYL 2597
C+NT GSF C C++G+ L +C+D+DEC C H C N G ++C C +GY+
Sbjct: 294 DHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYI 353
Query: 2598 QHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINEC---GS 2654
Y C D +EC ++ C NT GSY+C+CP G + C + +C
Sbjct: 354 L-YGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAK 412
Query: 2655 AQAPCSYGCSNTEGGYLC--GCP 2675
CS G C CP
Sbjct: 413 TSPRAQLSCSKAGGVESCFLSCP 435
Score = 201 bits (510), Expect = 1e-50
Identities = 132/417 (31%), Positives = 187/417 (44%), Gaps = 43/417 (10%)
Query: 2206 DINECAQNPLLCAFR--CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHD--CTEK 2261
D++EC++ C C NT SY+C C GY + + + C+D DECE ++ C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDIDECENDYYNGGCVH- 89
Query: 2262 QMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDG 2321
EC N+ G Y C C G+ DG C+D +ECQ G C+ C+N GSY C+C+ G
Sbjct: 90 --ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSG 146
Query: 2322 FTASPNQDECLD---------NREGYCFTEVLQNM-------CQIGSSNRNPVTKSECCC 2365
F S NQ C+ N++ C + C+ G C
Sbjct: 147 FFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTC 206
Query: 2366 DGGRGWGPH-CEICPFQGTVA-FKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRG 2423
+ G G H CE T +K H G I+ C V + C + C +
Sbjct: 207 NYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC----IETCAVNNGGC-DRTCKDTAT 261
Query: 2424 SYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSC 2483
C C G+T G +C D+NEC C+ C+NT GS++C C KGY L D R+C
Sbjct: 262 GVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTC 321
Query: 2484 KDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTS-CIDNNECTSDINLCGSKGICQ 2542
+D+DEC+ + C +C+N+ G F C C G+ + T+ C D +EC+ C C
Sbjct: 322 QDIDECSF-ERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQG--CV 378
Query: 2543 NTPGSFTCECQRGFSLDQTGSSCEDVDEC----EGNHRCQHGCQNIIGGYRC--SCP 2593
NT GS+ C C G L G C + +C + + R Q C G C SCP
Sbjct: 379 NTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCP 435
Score = 192 bits (488), Expect = 4e-48
Identities = 135/439 (30%), Positives = 194/439 (44%), Gaps = 54/439 (12%)
Query: 1849 DRNECQEIPNICS-HGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT--- 1904
D +EC E + C C +T S+ CLC G+K Q C DI+ECE D G
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQ--CEDIDECENDYYNGGCVHE 90
Query: 1905 CRNTIGSFNCRCNHGFILSHN-NDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYE 1963
C N G++ C C GF+L+H+ ++C+DVDEC NG C+ C+N +GS++CQC+ G+
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGG-CQQ-ICVNAMGSYECQCHSGFF 148
Query: 1964 VAPDGRTCVDINE----CLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVE 2019
++ + TC+ + C+ + CA + G C C PG+ L + + C
Sbjct: 149 LSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNY 208
Query: 2020 EPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHS 2079
C +C +T+ C C + ++L S GR C +
Sbjct: 209 GNGGCQ-HSCEDTDTGPTCGCHQKYALHSDGRTCIET----------------------- 244
Query: 2080 KQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAV-DMDECKEPDV-C 2137
CA+ G C+ T R CP G + PD D++EC + C
Sbjct: 245 -----CAVNNGGCDRTCKDTAT----GVRCSCPVG--FTLQPDGKTCKDINECLVNNGGC 293
Query: 2138 KHGQCINTDGSYRCECPFGYILAGNE--CVDTDECSVGNPCGNGTCKNVIGGFECTCEEG 2195
H C NT GS+ C C GY L +E C D DECS C + C N G F+C C G
Sbjct: 294 DHF-CRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDH-ICINSPGSFQCLCHRG 351
Query: 2196 FEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGK 2255
+ C D++EC+ + C CVNT GSYEC CP G L + + C + +C
Sbjct: 352 YILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRA 411
Query: 2256 HDCTEKQMECKNLIGTYMC 2274
Q+ C G C
Sbjct: 412 KTSPRAQLSCSKAGGVESC 430
Score = 191 bits (485), Expect = 9e-48
Identities = 128/394 (32%), Positives = 185/394 (46%), Gaps = 41/394 (10%)
Query: 989 GTEECE-ECPMRNTPE-YEELCPRGPGFATKEITNGKPFFKDINECK--MIPSLCTHGKC 1044
GT++C + +NTP+ Y+ LC PG+ + GK +DI+EC+ C H +C
Sbjct: 40 GTDDCHIDAICQNTPKSYKCLCK--PGYKGE----GKQC-EDIDECENDYYNGGCVH-EC 91
Query: 1045 RNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESG 1104
N G+++C C GF L + NC D+DEC+ + C + CVN G +EC+C SG
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC-QQICVNAMGSYECQC----HSG 146
Query: 1105 FMMMKNCMDIDECQRDPLLCR------GGVCHNT-EGSYRCECPPGHQLSPNISACIDIN 1157
F + N + + C +C T +G C+C PG L+ N C
Sbjct: 147 FFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDC--TL 204
Query: 1158 ECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEG 1217
C C + C + C C+ Y D C I+ C++ NGGC+ C ++
Sbjct: 205 TCNYGNGGCQHS-CEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDRTCKDTAT 261
Query: 1218 SYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKT 1277
CSC GF L PD ++C DI+EC N CD C N G + C C G+ D +T
Sbjct: 262 GVRCSCPVGFTLQPDGKTCKDINECLVNNGGCD-HFCRNTVGSFECGCRKGYKLLTDERT 320
Query: 1278 CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHA 1337
C D++EC C N+ GSF C C GY G T C D++EC + +C +
Sbjct: 321 CQDIDECSFERT--CDHICINSPGSFQCLCHRGYI-LYGTTHCGDVDECSMSNGSCDQG- 376
Query: 1338 VCTNTAGSFKCSCSPG----WIGDGIKCTDLDEC 1367
C NT GS++C C PG W +G C + +C
Sbjct: 377 -CVNTKGSYECVCPPGRRLHW--NGKDCVETGKC 407
Score = 190 bits (483), Expect = 2e-47
Identities = 130/433 (30%), Positives = 192/433 (44%), Gaps = 72/433 (16%)
Query: 530 DIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCI 588
D+DEC + C+ + C NT S+ C+C G+ +GK CED+DEC N NG C+
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCEDIDECE--NDYYNGGCV 88
Query: 589 NE----DGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLA 644
+E G+++C C GF LA DG C D++EC+ CVN GSY C+C G
Sbjct: 89 HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFF 148
Query: 645 VGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNS 704
+ + C+ + C + ++ C+ P
Sbjct: 149 LSDNQHTCIHR-----------------------SNEGMNCMNKDHGCAHICRETPKGGV 185
Query: 705 AEYQALCSSGPGMTSAGSDINECALDPDICPNGI---CENLRGTYKCICNSGYEVDSTGK 761
A C PG A + +C L + G CE+ C C+ Y + S G+
Sbjct: 186 A-----CDCRPGFDLAQNQ-KDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGR 239
Query: 762 NCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC--ESSPCING 819
C++ C +N+ CD C++T C+CP GF +PD KTC+DI+EC + C +
Sbjct: 240 TCIET--CAVNNGGCDR-TCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DH 295
Query: 820 VCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSL 879
C+N+ GSF C C L + C + I ++ D C IN G+ QC
Sbjct: 296 FCRNTVGSFECGCRKGYKLLTDERTC-QDIDECSFERTCDHIC-INSPGSF---QC---- 346
Query: 880 GAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPS 939
+C +GY T C D+DEC + G C G CVNT+GS++C CP
Sbjct: 347 ---------------LCHRGYILYGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPP 390
Query: 940 GMTLDATGRICLD 952
G L G+ C++
Sbjct: 391 GRRLHWNGKDCVE 403
Score = 186 bits (472), Expect = 3e-46
Identities = 119/374 (31%), Positives = 162/374 (43%), Gaps = 59/374 (15%)
Query: 2393 GRGFMTNGADIDECKVIHDVCR-NGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQA 2451
G + D+DEC D C + C N SY C+CK GY + G C D++EC
Sbjct: 24 GGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGE--GKQCEDIDECEND 81
Query: 2452 --PKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTC 2509
C C N G+Y+C+C G++L DG +C D+DEC CQ +CVN +G + C
Sbjct: 82 YYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYEC 141
Query: 2510 KCPPGF---TQHHTSCIDNNECTSDINLC-GSKGICQNTP-GSFTCECQRGFSLDQTGS- 2563
+C GF HT +NE + +N G IC+ TP G C+C+ GF L Q
Sbjct: 142 QCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKD 201
Query: 2564 --------------SCEDVDE-----------------------CEGNHRCQHGCQNIIG 2586
SCED D N C C++
Sbjct: 202 CTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTAT 261
Query: 2587 GYRCSCPQGYLQHYQWNQCVDENECLSAHICGGAS--CHNTLGSYKCMCPAGFQYEQFSG 2644
G RCSCP G+ C D NECL + GG C NT+GS++C C G++
Sbjct: 262 GVRCSCPVGFTLQPDGKTCKDINECLVNN--GGCDHFCRNTVGSFECGCRKGYKLLTDER 319
Query: 2645 GCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGE 2704
CQDI+EC S + C + C N+ G + C C GY G HC G + +G
Sbjct: 320 TCQDIDEC-SFERTCDHICINSPGSFQCLCHRGYILYGTTHC------GDVDECSMSNGS 372
Query: 2705 MDDNSLSPEACYEC 2718
D ++ + YEC
Sbjct: 373 CDQGCVNTKGSYEC 386
Score = 186 bits (471), Expect = 4e-46
Identities = 204/816 (25%), Positives = 300/816 (36%), Gaps = 129/816 (15%)
Query: 1606 DIDECQELPGLCQ-GGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGT-- 1662
D+DEC E C C NT S++C C GY + + C+D++ECE G
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDIDECENDYYNGGCVHE 90
Query: 1663 CYNTVGNYTCICPPDYMQVNGGNNCMDMR---------RSLCYRNYYADNQTCDGELLFN 1713
C N GNY C C +M + G+NC+D+ + +C + C +
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 1714 MTKKMCCCSYNIGRAWNKPCEQCP--IPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECR 1771
+ C N G C T + C RPGF D+ C
Sbjct: 151 DNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDC-RPGF--DLAQNQKDCTLTCN 207
Query: 1772 EIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSY 1831
G C++ C + C C + + C + NG C R C +TA
Sbjct: 208 YGNGGCQHS-CEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGG-CDRT--CKDTATGV 263
Query: 1832 RCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCL 1890
RC C G+ G+ C D NEC C H C +TVGSF C C G+K D+ C
Sbjct: 264 RCSCPVGFTLQPDGKTCKDINECLVNNGGCDHF-CRNTVGSFECGCRKGYKLLTDERTCQ 322
Query: 1891 DINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINT 1950
DI+EC + + C N+ GSF C C+ G+IL C DVDEC+ NG+ C G C+NT
Sbjct: 323 DIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGS-CDQG-CVNT 380
Query: 1951 VGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC--APGTCQNLDGSYRC-ICPPGYSL- 2006
GS++C C G + +G+ CV+ +CL + A +C G C + P ++L
Sbjct: 381 KGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCPAHTLF 440
Query: 2007 --QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEG--------------------- 2043
+E + V P+ AL + T C +
Sbjct: 441 VPDSENSYVLSCGVPGPQGKALQKRNGTSSGLGPSCSDAPTTPIKQKARFKIRDAKCHLR 500
Query: 2044 -FSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSR-----------NHSKQECCCALKGEG 2091
S + + + + +C+ F KC S K R +H E K E
Sbjct: 501 PHSQARAKETARQPLLDHCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEIETKMEE 560
Query: 2092 WGDPCEL-CPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYR 2150
D CE C + E Q +G V + + + + + G+
Sbjct: 561 ASDTCEADCLRKRAEQSLQAAIKTLRKSIGRQQFYVQVSGTEYEVAQRPAKALEGQGA-- 618
Query: 2151 CECPFGYILAGNECVDTDECSVGN----------PCGNGTCKNVIGGFECTCEEGFEPGP 2200
C G +L ++CV C G C GT +++ G CT +
Sbjct: 619 --CGAGQVLQDSKCV---ACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGLG 673
Query: 2201 MMTCEDINECAQNPLLCAFRCVNTYGSYECK-CPVG-YVLREDRRMCKDEDECEEG---K 2255
+ +++EC C+ + G C+ CPVG Y R C C G K
Sbjct: 674 LPGARNVSECGGQ---CSPGFFSADGFKPCQACPVGTYQPEPGRTGC---FPCGGGLLTK 727
Query: 2256 HDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCV-----------DENECQTKPG---- 2300
H+ T +C+ + C PG+ C+ +N C T PG
Sbjct: 728 HEGTTSFQDCEAKVH-----CSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCITCPGNTST 782
Query: 2301 ---------ICENGRCLNTRGSYTCECNDGFTASPN 2327
C+N C G YT G+ SPN
Sbjct: 783 DFDGSTNVTHCKNQHCGGELGDYT-----GYIESPN 813
Score = 184 bits (468), Expect = 8e-46
Identities = 121/417 (29%), Positives = 168/417 (40%), Gaps = 88/417 (21%)
Query: 2308 LNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDG 2367
L TRG G S + DEC + + C I + +N +C C
Sbjct: 16 LGTRGRLAG--GSGLPGSVDVDECSEGTDD----------CHIDAICQNTPKSYKCLCKP 63
Query: 2368 G-RGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNG---ECVNDRG 2423
G +G G CE DIDEC+ +D G EC+N G
Sbjct: 64 GYKGEGKQCE-------------------------DIDECE--NDYYNGGCVHECINIPG 96
Query: 2424 SYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSC 2483
+Y C C G+ G +C+D++EC C IC N GSY+C C G+ L ++ +C
Sbjct: 97 NYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Query: 2484 ----KDLDECATKQHNCQFLCVNTI-GGFTCKCPPGF--TQHHTSCI------------- 2523
+ C K H C +C T GG C C PGF Q+ C
Sbjct: 157 IHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHS 216
Query: 2524 --------------------DNNEC--TSDINLCGSKGICQNTPGSFTCECQRGFSLDQT 2561
D C T +N G C++T C C GF+L
Sbjct: 217 CEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPD 276
Query: 2562 GSSCEDVDEC-EGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGA 2620
G +C+D++EC N C H C+N +G + C C +GY C D +EC C
Sbjct: 277 GKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHI 336
Query: 2621 SCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPG 2677
C N+ GS++C+C G+ + C D++EC + C GC NT+G Y C CPPG
Sbjct: 337 -CINSPGSFQCLCHRGYILYGTTH-CGDVDECSMSNGSCDQGCVNTKGSYECVCPPG 391
Score = 182 bits (462), Expect = 4e-45
Identities = 128/415 (30%), Positives = 182/415 (43%), Gaps = 61/415 (14%)
Query: 1312 SGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGT 1371
+G G G D++EC G +C A+C NT S+KC C PG+ G+G +C D+DEC N
Sbjct: 23 AGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDY 82
Query: 1372 HMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRC 1429
+ +C N G+YRC C +G+ DG C D+DEC +N C C+NA G Y C
Sbjct: 83 YNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC-QQICVNAMGSYEC 141
Query: 1430 ECDMGFVPSADGKAC-----EDIDECSLPNICVFGTCHNLP-GLFRCECEIGYELDRSGG 1483
+C GF S + C E ++ + + C C P G C+C G++L ++
Sbjct: 142 QCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH-ICRETPKGGVACDCRPGFDLAQNQK 200
Query: 1484 NCTDVNECLDPTTCISGN------CVNTPGSYICDCPPDFELNPTRVGCVDT---RSGNC 1534
+CT TC GN C +T C C + L+ C++T +G C
Sbjct: 201 DCT--------LTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGC 252
Query: 1535 YLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVN------------- 1581
D C + GV C C +G + C +N
Sbjct: 253 -----------DRTC-KDTATGV---RCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFC 297
Query: 1582 -TSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLN 1640
+ C +G++ +DIDEC C CIN+ GSFQC C GY L
Sbjct: 298 RNTVGSFECGCRKGYKLLTDERTCQDIDEC-SFERTCD-HICINSPGSFQCLCHRGYILY 355
Query: 1641 EDTRVCDDVNECE-TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSL 1694
T C DV+EC + G C G C NT G+Y C+CPP G +C++ + L
Sbjct: 356 GTTH-CGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCL 408
Score = 177 bits (448), Expect = 2e-43
Identities = 119/357 (33%), Positives = 160/357 (44%), Gaps = 53/357 (14%)
Query: 489 IDVDECEK--NPC-AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNG- 544
+DVDEC + + C C N SY C C+ GY+ +C DIDEC + N G
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGE--GKQCEDIDECEND--YYNGGC 87
Query: 545 --RCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGF 602
CIN G++ C C GF + DG NC D+DEC N +C+N GS++C C GF
Sbjct: 88 VHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGF 147
Query: 603 QLASDGRYCKDINECETPGICMNGR------CVNT-DGSYRCECFPGLAVGLDGRVCVDT 655
L+ + C I+ CMN C T G C+C PG + + + C
Sbjct: 148 FLSDNQHTC--IHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCT-- 203
Query: 656 HMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGP 715
TC Y G C T C C +YA + C
Sbjct: 204 ---LTC--NYGNGGCQHSCEDTDTGPTCGC-HQKYALHSDGRTC---------------- 241
Query: 716 GMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLL 775
I CA++ C + C++ +C C G+ + GK C DINEC++N+
Sbjct: 242 --------IETCAVNNGGC-DRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGG 292
Query: 776 CDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICEC 832
CD+ CRNT GSF C C KG+ D +TC+DIDEC + +C NSPGSF C C
Sbjct: 293 CDH-FCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLC 348
Score = 160 bits (406), Expect = 1e-38
Identities = 122/416 (29%), Positives = 182/416 (43%), Gaps = 61/416 (14%)
Query: 450 TDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGG---ECIN 506
TD C + +CQN TP S +C C G++ + + +C D+DECE + GG ECIN
Sbjct: 41 TDDCH-IDAICQN-----TPKSYKCLCKPGYKGEGK-QCEDIDECENDYYNGGCVHECIN 93
Query: 507 NQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGF----- 561
G+Y C C G+ C D+DEC N C C+N GS+ C C++GF
Sbjct: 94 IPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHSGFFLSDN 152
Query: 562 -----HVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINE 616
H + +G NC + D ++C G C C+PGF LA + + C
Sbjct: 153 QHTCIHRSNEGMNCMNKDH-GCAHICRE----TPKGGVACDCRPGFDLAQNQKDCTLTCN 207
Query: 617 CETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFG 676
G C + C +TD C C A+ DGR C++T C G C +
Sbjct: 208 YGNGG-CQHS-CEDTDTGPTCGCHQKYALHSDGRTCIET-----C--AVNNGGCDRTCKD 258
Query: 677 AVTKSECCC--ASTEYAFGEPCQP---CPAQNSA----------EYQALCSSGPGMTS-- 719
T C C T G+ C+ C N ++ C G + +
Sbjct: 259 TATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDE 318
Query: 720 -AGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDN 778
DI+EC+ + + IC N G+++C+C+ GY + T +C D++EC +++ CD
Sbjct: 319 RTCQDIDECSFERTC--DHICINSPGSFQCLCHRGYILYGT-THCGDVDECSMSNGSCDQ 375
Query: 779 GQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC----ESSPCINGVCKNSPGSFIC 830
G C NT GS+ C CP G + K C + +C ++SP C + G C
Sbjct: 376 G-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESC 430
Score = 146 bits (369), Expect = 3e-34
Identities = 133/474 (28%), Positives = 181/474 (38%), Gaps = 111/474 (23%)
Query: 807 DIDECE--SSPC-INGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCE 863
D+DEC + C I+ +C+N+P S+ C +C KG Q CE
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKC-------------LCKPGYKGEGKQCEDIDECE 79
Query: 864 ININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIK-GTQCEDIDECEVFPGVCK 922
+ +C + G CT C G+ G C D+DEC+ G C+
Sbjct: 80 NDYYNGGCVHECINIPG---NYRCT-------CFDGFMLAHDGHNCLDVDECQDNNGGCQ 129
Query: 923 NGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLE--TCF--------------------- 959
+CVN GS++CQC SG L C+ E C
Sbjct: 130 Q-ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACD 188
Query: 960 ------LRYEDEECTL-------------------PIAGRHR-----MDACCCSVGAAWG 989
L ++CTL P G H+ D C A
Sbjct: 189 CRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVN 248
Query: 990 TEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIG 1049
C+ CP GF + +GK KDINEC + C H CRNT+G
Sbjct: 249 NGGCDRTCKDTATGVRCSCP--VGFTLQ--PDGKT-CKDINECLVNNGGCDH-FCRNTVG 302
Query: 1050 SFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMK 1109
SF+C C G+ L ++ER C DIDEC C C+N+PG F+C C GY
Sbjct: 303 SFECGCRKGYKLLTDERTCQDIDECSFE-RTCDH-ICINSPGSFQCLCHRGYI--LYGTT 358
Query: 1110 NCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNG 1169
+C D+DEC C G C NT+GSY C CPPG +L N C++ +C A P
Sbjct: 359 HCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSP-- 415
Query: 1170 RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSC 1223
+ Q +C+ ++ C + F +SE SY SC
Sbjct: 416 -------RAQLSCSK----------AGGVESCFLSCPAHTLFVPDSENSYVLSC 452
Score = 145 bits (367), Expect = 4e-34
Identities = 193/806 (23%), Positives = 276/806 (34%), Gaps = 195/806 (24%)
Query: 465 CIPTPGSCRCECNKGFQLDLRGE-CIDVDECEKNPCAGGE-CINNQGSYTCQCRAGY--- 519
CI PG+ RC C GF L G C+DVDEC+ N + C+N GSY CQC +G+
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 520 ---QSTLTRT---------------------------ECRDIDECLQNGR----ICNNGR 545
+ + R+ +CR + QN + CN G
Sbjct: 151 DNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGN 210
Query: 546 ------CINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICK 599
C +TD C C+ + + DG+ C ++ C++ N + C + +C C
Sbjct: 211 GGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNGGCDRTCKDTATGVRCSCP 268
Query: 600 PGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRS 659
GF L DG+ CKDINEC + C NT GS+ C C G + D R C D
Sbjct: 269 VGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDI---- 324
Query: 660 TCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGP---G 716
EC +F C + +Q LC G G
Sbjct: 325 ---------------------DEC-------SFERTCDHICINSPGSFQCLCHRGYILYG 356
Query: 717 MTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC 776
T G D++EC++ C G C N +G+Y+C+C G + GK+CV+ +C+ +
Sbjct: 357 TTHCG-DVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTS 414
Query: 777 DNGQ--CRNTPGSFVC--TCPKGFIYKPDLKTCEDIDECESSPCINGVCK-NSPGSFICE 831
Q C G C +CP ++ PD + + P + K N S +
Sbjct: 415 PRAQLSCSKAGGVESCFLSCPAHTLFVPDSENSYVLSCGVPGPQGKALQKRNGTSSGLGP 474
Query: 832 CSSESTLDPTKTICIETI---------------KGTCWQTVIDGRCEININGATLKSQCC 876
S++ P K I K T Q ++D C + TLK C
Sbjct: 475 SCSDAPTTPIKQKARFKIRDAKCHLRPHSQARAKETARQPLLD-HCHVTF--VTLK--CD 529
Query: 877 SSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQ 936
SS G +V I + K + D E + C+ R Q
Sbjct: 530 SSKKRRRGRKSPSKEVSHITAEFEIETKMEEASDTCEAD----------CLRKRAEQSLQ 579
Query: 937 CPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEEC 996
+ GR +++ E E P A C G +C C
Sbjct: 580 AAIKTLRKSIGRQQFYVQVSGT----EYEVAQRPAKALEGQGA--CGAGQVLQDSKCVAC 633
Query: 997 PMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCR-C 1055
GP G F ++ +C C G ++ G C C
Sbjct: 634 --------------GP---------GTHFGGELGQCVS----CMPGTYQDMEGQLSCTPC 666
Query: 1056 DSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDID 1115
S L ++ EC GQC +PG F GF + C +
Sbjct: 667 PSSDGLGLP--GARNVSEC--------GGQC--SPGFFSA-------DGFKPCQAC-PVG 706
Query: 1116 ECQRDP-----LLCRGGVCHNTEGS---YRCE----CPPGHQLSPNISACIDINECELSA 1163
Q +P C GG+ EG+ CE C PGH + CI
Sbjct: 707 TYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVHCSPGHHYNTTTHRCI--------- 757
Query: 1164 HLCPNGRCVNLIGKYQCACNPGYHST 1189
CP G G+ C PG ST
Sbjct: 758 -RCPVGTYQPEFGQNHCITCPGNTST 782
Score = 88.6 bits (218), Expect = 8e-17
Identities = 86/304 (28%), Positives = 118/304 (38%), Gaps = 76/304 (25%)
Query: 85 CRHSCGDGFCSRPNMCTCPSGQIAPSCG-----SRSIQHCNIRCM--NGG---SCSDDH- 133
C H C + P G +A C +++ + C + C NGG SC D
Sbjct: 173 CAHICRE----------TPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDT 222
Query: 134 ---CLCQKGYIGTHCGQPVCESGCLNGGRC-------VAPNRCACTYGFT----GPQCER 179
C C + Y G+ E+ +N G C RC+C GFT G C+
Sbjct: 223 GPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKD 282
Query: 180 DYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNI 239
C +++N C C TVG C CR+G+
Sbjct: 283 ---INEC--LVNNGGCDH----------FCRNTVG---SFECG--------CRKGYKLLT 316
Query: 240 RTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGIC 299
CQD+DEC + C CIN+ GSF+C C G+ L + C D+DECS G C
Sbjct: 317 DERTCQDIDEC-SFERTCDH-ICINSPGSFQCLCHRGYILYGTTH-CGDVDECSMSNGSC 373
Query: 300 EGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCC 359
+ G C NT SY C CPPG +G C++ G+C ++ S C
Sbjct: 374 DQG-CVNTKGSYECVCPPGRRLHWNGKDCVE-----------TGKCLSRAKTSPRAQLSC 421
Query: 360 CDAG 363
AG
Sbjct: 422 SKAG 425
Score = 84.3 bits (207), Expect = 2e-15
Identities = 98/332 (29%), Positives = 130/332 (39%), Gaps = 37/332 (11%)
Query: 46 GGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCI-VPICRHSCGDGFCSRPNMCTCPS 104
GG H+ + P Y C G+ G+ C+ V C+ + +G C + +C
Sbjct: 85 GGCVHECINIPG----NYRCTCFDGFMLAHDGHNCLDVDECQDN--NGGCQQ--ICVNAM 136
Query: 105 GQIAPSCGSRSI----QH-CNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGR 159
G C S QH C R G +C + C T G C+ G
Sbjct: 137 GSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDC---RPGF 193
Query: 160 CVAPNRCACT----YGFTGPQ--CERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATV 213
+A N+ CT YG G Q CE D TGP T +Q G C +T CA
Sbjct: 194 DLAQNQKDCTLTCNYGNGGCQHSCE-DTDTGP--TCGCHQKYALHSDGRTCIET--CAVN 248
Query: 214 GRAWGHPC-EMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECK 272
C + C GF C+D++EC G C C NTVGSFEC
Sbjct: 249 NGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHF-CRNTVGSFECG 307
Query: 273 CPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVR 332
C G+KL + C+DIDECS C+ C N+ S+ C C G Y T C DV
Sbjct: 308 CRKGYKLLTDERTCQDIDECS-FERTCD-HICINSPGSFQCLCHRG-YILYGTTHCGDVD 364
Query: 333 PGYCYTALTNGRCSNQLPQSITKMQCCCDAGR 364
+++NG C + +C C GR
Sbjct: 365 E----CSMSNGSCDQGCVNTKGSYECVCPPGR 392
Score = 72.8 bits (177), Expect = 5e-12
Identities = 73/274 (26%), Positives = 95/274 (34%), Gaps = 35/274 (12%)
Query: 67 CCPGWKTLPGGNQCIVPI------CRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCN 120
C PG+ C + C+HSC D C C S G I+ C
Sbjct: 189 CRPGFDLAQNQKDCTLTCNYGNGGCQHSCED--TDTGPTCGCHQKYALHSDGRTCIETCA 246
Query: 121 IRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERD 180
+ N G C C+ G C PV + +G C N C G C+
Sbjct: 247 V---NNGGCDRT---CKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNG----GCDHF 296
Query: 181 YRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVG-----RAWGHPCEMCPAQPHP-CRRG 234
C + + C + + T C + R H C P C RG
Sbjct: 297 -----CRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRG 351
Query: 235 FIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDEC-- 292
+I T C DVDEC G C G C+NT GS+EC CP G +L+ + C + +C
Sbjct: 352 YIL-YGTTHCGDVDECSMSNGSCDQG-CVNTKGSYECVCPPGRRLHWNGKDCVETGKCLS 409
Query: 293 --STIPGICEGGECTNTVSSYFCKCPPGFYTSPD 324
T P V S F CP PD
Sbjct: 410 RAKTSPRAQLSCSKAGGVESCFLSCPAHTLFVPD 443
Score = 56.6 bits (135), Expect = 3e-07
Identities = 61/257 (23%), Positives = 80/257 (31%), Gaps = 92/257 (35%)
Query: 165 RCACTYGFTGP--------QCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRA 216
+C C G+ G +CE DY G C
Sbjct: 58 KCLCKPGYKGEGKQCEDIDECENDYYNGGCV----------------------------- 88
Query: 217 WGHPCEMCPAQPH-PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPA 275
H C P C GF+ C DVDECQ G CQ C+N +GS+EC+C +
Sbjct: 89 --HECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQ-ICVNAMGSYECQCHS 145
Query: 276 G-----------HKLNEVSQKCEDIDE---------------CSTIPGI----------- 298
G H+ NE C + D C PG
Sbjct: 146 GFFLSDNQHTCIHRSNE-GMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTL 204
Query: 299 -CEGGE------CTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQ 351
C G C +T + C C + DG CI+ A+ NG C
Sbjct: 205 TCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIET------CAVNNGGCDRTCKD 258
Query: 352 SITKMQCCCDAGRCWSP 368
+ T ++C C G P
Sbjct: 259 TATGVRCSCPVGFTLQP 275
Score = 40.4 bits (93), Expect = 0.025
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 5/77 (6%)
Query: 288 DIDECSTIPGICE-GGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCS 346
D+DECS C C NT SY C C PG+ +G +C D+ C NG C
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDI--DECENDYYNGGCV 88
Query: 347 NQLPQSITKMQCCCDAG 363
++ +C C G
Sbjct: 89 HECINIPGNYRCTCFDG 105
Score = 38.9 bits (89), Expect = 0.074
Identities = 52/194 (26%), Positives = 64/194 (32%), Gaps = 41/194 (21%)
Query: 1222 SCQPG-FALMPDQRSCTDIDECEDNPNICDGGQCTNIPG-----EYRCLCYDGFMASEDM 1275
SC PG + M Q SCT C +PG E C GF +++
Sbjct: 648 SCMPGTYQDMEGQLSCTP----------CPSSDGLGLPGARNVSECGGQCSPGFFSADGF 697
Query: 1276 KTCVDVNECDLNPNICLSGTCENTKGSFICH-CDMGYSGKKGKTGCTDINECEIGAHNCG 1334
K C C GT + G C C G K G T +CE H
Sbjct: 698 KPC----------QACPVGTYQPEPGRTGCFPCGGGLLTKH--EGTTSFQDCEAKVHCSP 745
Query: 1335 KHAVCTNTAGSFKCSCSPGWIGDG----IKC-----TDLDECSNGTHMCSQHADCKNTMG 1385
H T T +C G I C TD D +N TH +QH C +G
Sbjct: 746 GHHYNTTTHRCIRCPVGTYQPEFGQNHCITCPGNTSTDFDGSTNVTHCKNQH--CGGELG 803
Query: 1386 SYRCLCKE-GYTGD 1398
Y + Y GD
Sbjct: 804 DYTGYIESPNYPGD 817
Score = 32.3 bits (72), Expect = 6.9
Identities = 51/208 (24%), Positives = 66/208 (31%), Gaps = 62/208 (29%)
Query: 1545 GDTACSNEIGVGVSKASC-CCSLGKAWGTPCEMCPAVNTSEYKIL--------CPGGEGF 1595
G AC G + + C C G +G C + Y+ + CP +G
Sbjct: 615 GQGACG--AGQVLQDSKCVACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGL 672
Query: 1596 R-PNPITVILEDIDECQELPGLCQGGKCINTF----GSFQCR-CPTGYYLNEDTRV---- 1645
P ++ EC GG+C F G C+ CP G Y E R
Sbjct: 673 GLPGA-----RNVSEC--------GGQCSPGFFSADGFKPCQACPVGTYQPEPGRTGCFP 719
Query: 1646 -----------CDDVNECETPGICGPGTCYNTVGNYTCICP-PDYMQVNGGNNCMDMRRS 1693
+CE C PG YNT + CP Y G N+C+
Sbjct: 720 CGGGLLTKHEGTTSFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCI----- 774
Query: 1694 LCYRNYYAD-----------NQTCDGEL 1710
C N D NQ C GEL
Sbjct: 775 TCPGNTSTDFDGSTNVTHCKNQHCGGEL 802
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 214 bits (544), Expect = 1e-54
Identities = 243/876 (27%), Positives = 336/876 (38%), Gaps = 199/876 (22%)
Query: 1109 KNCMDI---DECQRDPLLCRGGVCHNTEGSYR----CECPPGHQLSPNISACIDINECEL 1161
K CM+ EC R +CR G C GS + C C G Q CI
Sbjct: 218 KTCMEGWMGPECNR--AICRQG-CSPKHGSCKLPGDCRCQYGWQ-GLYCDKCI------- 266
Query: 1162 SAHLCPNGRCVNLIGK--YQCACNP---GYHSTPDRLFCVDIDECSIMNGGCETFCTNS- 1215
P+ CV+ I +QC C G D +C C +NGG C+N+
Sbjct: 267 -----PHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPC--LNGGT---CSNTG 316
Query: 1216 EGSYECSCQPGFALMPD----QRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMA 1271
Y+CSC G++ P+ + +C D C + G C + C C G+
Sbjct: 317 PDKYQCSCPEGYS-GPNCEIAEHACLS-DPCHNR------GSCKETSLGFECECSPGWTG 368
Query: 1272 SEDMKTCVDVNECDLNPNICL-SGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGA 1330
TC N D +PN C GTC++ F C C ++GK T D NECE A
Sbjct: 369 P----TC-STNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGK---TCQLDANECE--A 418
Query: 1331 HNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL 1390
C C N S+ C C PGW+G ++++C C A C++ + YRC+
Sbjct: 419 KPCVNAKSCKNLIASYYCDCLPGWMGQNCDI-NINDCLG---QCQNDASCRDLVNGYRCI 474
Query: 1391 CKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE-DIDE 1449
C GY GD D+DEC+ N L G G C N ++C C GF G C+ DID
Sbjct: 475 CPPGYAGDHCE-RDIDECASNPCLNG-GHCQNEINRFQCLCPTGF----SGNLCQLDIDY 528
Query: 1450 CSLPNICVFGT-CHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGS 1508
C PN C G C+N + C+C YE G NC+ + + +C TP
Sbjct: 529 CE-PNPCQNGAQCYNRASDYFCKCPEDYE----GKNCSHLKD----------HCRTTPCE 573
Query: 1509 YICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGK 1568
I C N DT G Y+ G +G C ++ G K +C C+ G
Sbjct: 574 VIDSCTVAMASN-------DTPEGVRYISSNVCGPHG--KCKSQSG---GKFTCDCNKGF 621
Query: 1569 AWGT-------PCEMCPAVN-------TSEYKILCPGG-EGFRPNPITVILEDIDECQEL 1613
GT CE P N + YK +C G EG +I++C +
Sbjct: 622 T-GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG------AYCETNINDCSQN 674
Query: 1614 PGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDD-VNECETPGICGPGTCYNTVGNYTC 1672
P GG C + F C C G+ + C ++C+ GTCY+ + C
Sbjct: 675 P-CHNGGTCRDLVNDFYCDCKNGW----KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC 729
Query: 1673 ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKP 1732
+CP + G C R S C N + TC + N C C W P
Sbjct: 730 MCPGGW----EGTTCNIARNSSCLPNPCHNGGTC----VVNGESFTCVCK----EGWEGP 777
Query: 1733 -CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFR 1790
C Q + ++C P C N G C++ +R
Sbjct: 778 ICAQ------------------------------NTNDCS--PHPCYNSGTCVDGDNWYR 805
Query: 1791 CECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDR 1850
CEC GF D + +I+ECQ+ P C A C++ YRC C PG+
Sbjct: 806 CECAPGFAGPDCRI---NINECQSSP-CAFGATCVDEINGYRCVCPPGH---------SG 852
Query: 1851 NECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDIN---ECERDACGNGTCRN 1907
+CQE+ S CI T+GS + G K +DD C +N C + CG C
Sbjct: 853 AKCQEV----SGRPCI-TMGS---VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLL 904
Query: 1908 TIGSFNCRCNHGFILSHNNDCI-----DVDECASGN 1938
G C I ++ C V EC S +
Sbjct: 905 HKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSS 940
Score = 211 bits (537), Expect = 8e-54
Identities = 192/710 (27%), Positives = 286/710 (40%), Gaps = 118/710 (16%)
Query: 1027 KDINECKMIPSLCTHGKCRNT-IGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ 1085
KD+N C G C NT ++C C G++ NC + +S RG
Sbjct: 295 KDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYS----GPNCEIAEHACLSDPCHNRGS 350
Query: 1086 CVNTPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLLC-RGGVCHNTEGSYRCECPPG 1143
C T FEC+C G+ C +ID+C P C GG C + ++C CPP
Sbjct: 351 CKETSLGFECECSPGWTG-----PTCSTNIDDC--SPNNCSHGGTCQDLVNGFKCVCPPQ 403
Query: 1144 HQLSPNISACIDINECELSAHLCPNGR-CVNLIGKYQCACNPGYHSTPDRLFCVDIDECS 1202
+ +D NECE A C N + C NLI Y C C PG+ + ++I++C
Sbjct: 404 W---TGKTCQLDANECE--AKPCVNAKSCKNLIASYYCDCLPGWMG---QNCDININDCL 455
Query: 1203 IMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE 1260
G C + C + Y C C PG+A +R DIDEC NP + +GG C N
Sbjct: 456 ---GQCQNDASCRDLVNGYRCICPPGYAGDHCER---DIDECASNPCL-NGGHCQNEINR 508
Query: 1261 YRCLCYDGFMASEDMKTC-VDVNECDLNPNICLSGT-CENTKGSFICHCDMGYSGKK--- 1315
++CLC GF + C +D++ C+ PN C +G C N + C C Y GK
Sbjct: 509 FQCLCPTGFSGN----LCQLDIDYCE--PNPCQNGAQCYNRASDYFCKCPEDYEGKNCSH 562
Query: 1316 -----GKTGCTDINECE--------------IGAHNCGKHAVC-TNTAGSFKCSCSPGWI 1355
T C I+ C I ++ CG H C + + G F C C+ G+
Sbjct: 563 LKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Query: 1356 GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLC 1415
G ++++C ++ C C + + SY+C+C +G+ G + T++++CS+ N C
Sbjct: 623 GTYCH-ENINDCE--SNPCRNGGTCIDGVNSYKCICSDGWEG-AYCETNINDCSQ--NPC 676
Query: 1416 GN-GQCLNAPGGYRCECDMGFVPSADGKACEDID-ECSLPNICVFGTCHNLPGLFRCECE 1473
N G C + + C+C G+ GK C D +C GTC++ F+C C
Sbjct: 677 HNGGTCRDLVNDFYCDCKNGW----KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCP 732
Query: 1474 IGYELDRSGGNCTDV--NECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRS 1531
G+E G C + CL G CV S+ C C +E D
Sbjct: 733 GGWE----GTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSP 788
Query: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAV--NTSEYKILC 1589
CY +GD E G + C ++ + +PC + Y+ +C
Sbjct: 789 HPCYNS--GTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVC 846
Query: 1590 PGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDV 1649
P G +CQE+ G CI T GS P G ++D C +
Sbjct: 847 PPGHSGA------------KCQEV----SGRPCI-TMGSV---IPDGAKWDDDCNTCQCL 886
Query: 1650 N---ECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCY 1696
N C CGP C G+ C G +C+ + C+
Sbjct: 887 NGRIACSKVW-CGPRPCLLHKGHSEC---------PSGQSCIPILDDQCF 926
Score = 203 bits (517), Expect = 2e-51
Identities = 214/816 (26%), Positives = 321/816 (39%), Gaps = 187/816 (22%)
Query: 1952 GSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP--GTCQNLDGSYRCICPPGYSLQNE 2009
G + C N G + +G + N + + C+P G+C+ L G RC Y Q
Sbjct: 208 GHYACDQN-GNKTCMEGWMGPECNRAICR-QGCSPKHGSCK-LPGDCRC----QYGWQGL 260
Query: 2010 KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK---FE 2066
C D+C+ P C G C+ ++CLC + G+ C D ++YC
Sbjct: 261 YC---DKCIPHPG-CVHGICNEP---WQCLCETNWG----GQLC-DKDLNYCGTHQPCLN 308
Query: 2067 GGKCSSPKSRNHSKQECCCALKGEGWGDP-CELCPTEPDEAFRQICPYGSGIIVGPDDSA 2125
GG CS+ K +C C EG+ P CE+ + A
Sbjct: 309 GGTCSNT---GPDKYQCSCP---EGYSGPNCEIA-----------------------EHA 339
Query: 2126 VDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC-VDTDECSVGNPCGNGTCKNV 2184
D C G C T + CEC G+ G C + D+CS N GTC+++
Sbjct: 340 CLSDPCHN-----RGSCKETSLGFECECSPGW--TGPTCSTNIDDCSPNNCSHGGTCQDL 392
Query: 2185 IGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRR 2243
+ GF+C C + TC+ D NEC P + A C N SY C C G++
Sbjct: 393 VNGFKCVCPPQWTG---KTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWM------ 443
Query: 2244 MCKDEDECEEGKHDCT---EKQMECKNLIGTYMCICGPGYQRRPDGEGCV-DENECQTKP 2299
C+ +DC + C++L+ Y CIC PGY G+ C D +EC + P
Sbjct: 444 ----GQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECASNP 495
Query: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
+ G C N + C C GF+ + Q + YC N CQ G+ N +
Sbjct: 496 CL-NGGHCQNEINRFQCLCPTGFSGNLCQLDI-----DYCEP----NPCQNGAQCYNRAS 545
Query: 2360 KSECCCDG---GRGWG---PHCEICPFQG----TVAF-------------KKLC-PHGRG 2395
C C G+ HC P + TVA +C PHG+
Sbjct: 546 DYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKC 605
Query: 2396 FMTNGA-----------------DIDECKVIHDVCRNG-ECVNDRGSYHCICKTGYTPDI 2437
+G +I++C+ + CRNG C++ SY CIC G+
Sbjct: 606 KSQSGGKFTCDCNKGFTGTYCHENINDCE--SNPCRNGGTCIDGVNSYKCICSDGWE--- 660
Query: 2438 TGTSC-VDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLD-ECATKQHN 2495
G C ++N+C+Q P C++ + C C G+ G++C D +C N
Sbjct: 661 -GAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW----KGKTCHSRDSQCDEATCN 715
Query: 2496 CQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRG 2555
C + F C CP G+ + N+ C N C + G C SFTC C+ G
Sbjct: 716 NGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLP--NPCHNGGTCVVNGESFTCVCKEG 773
Query: 2556 FSLDQTGSSC-EDVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQC-VDENEC 2611
+ G C ++ ++C H C + C + YRC C G+ C ++ NEC
Sbjct: 774 WE----GPICAQNTNDCSP-HPCYNSGTCVDGDNWYRCECAPGFAGP----DCRININEC 824
Query: 2612 LSAHICGGASCHNTLGSYKCMCP---AGFQYEQFSG------------GCQDINECGSAQ 2656
S+ GA+C + + Y+C+CP +G + ++ SG G + ++C + Q
Sbjct: 825 QSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQ 884
Query: 2657 APCSYG---CSNTEGGYLCGCPPGYFRIGQGHCVSG 2689
C G CS CG P G C SG
Sbjct: 885 --CLNGRIACSKV----WCGPRPCLLHKGHSECPSG 914
Score = 194 bits (492), Expect = 1e-48
Identities = 207/790 (26%), Positives = 307/790 (38%), Gaps = 158/790 (20%)
Query: 1652 CETPGICGPGTC-YNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGEL 1710
C+ PG C C Y G Y C P V+G C + + LC N+ Q CD +L
Sbjct: 245 CKLPGDC---RCQYGWQGLYCDKCIPHPGCVHG--ICNEPWQCLCETNW--GGQLCDKDL 297
Query: 1711 LFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDEC 1770
+ T + C N G C D++ C Y+G +I E
Sbjct: 298 NYCGTHQPCL---NGGT--------CSNTGPDKYQCSCPEG--------YSGPNCEIAEH 338
Query: 1771 REIPGVCEN-GVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAG 1829
+ C N G C F CEC G+ +ID+C C C +
Sbjct: 339 ACLSDPCHNRGSCKETSLGFECECSPGW---TGPTCSTNIDDCSPNN-CSHGGTCQDLVN 394
Query: 1830 SYRCDCKPGYRFTSTGQ-CN-DRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQT 1887
++C C P + TG+ C D NEC+ P + + C + + S+YC C G+ Q
Sbjct: 395 GFKCVCPPQW----TGKTCQLDANECEAKPCVNAKS-CKNLIASYYCDCLPGWM---GQN 446
Query: 1888 MCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRN-GQ 1946
++IN+C + +CR+ + + C C G+ H D+DECAS N C N G
Sbjct: 447 CDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCER--DIDECAS---NPCLNGGH 501
Query: 1947 CINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGT-CQNLDGSYRCICPPGY 2004
C N + FQC C G+ G C +DI+ C EP C G C N Y C CP Y
Sbjct: 502 CQNEINRFQCLCPTGF----SGNLCQLDIDYC--EPNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 2005 SLQN----------EKCEDIDECV------EEPE--------ICA-LGTC-SNTEGSFKC 2038
+N CE ID C + PE +C G C S + G F C
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 2039 LCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCEL 2098
C +GF+ + D + C GG C + +C C+ +GW
Sbjct: 616 DCNKGFTGTYCHENINDCESNPCR---NGGTCID----GVNSYKCICS---DGWEG--AY 663
Query: 2099 CPTEPDEAFRQICPYGSGIIVGPDDSAVDM-------------DECKEPDVCKHGQCINT 2145
C T ++ + C G +D D +C E G C +
Sbjct: 664 CETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDE 723
Query: 2146 DGSYRCECPFGYILAGNEC-VDTDECSVGNPCGN-GTCKNVIGG--FECTCEEGFEPGPM 2201
+++C CP G+ G C + + + NPC N GTC V+ G F C C+EG+E GP
Sbjct: 724 GDAFKCMCPGGW--EGTTCNIARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWE-GP- 777
Query: 2202 MTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEK 2261
+ ++ N+C+ +P + CV+ Y C+C G+ +C ++C
Sbjct: 778 ICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFA----------GPDCRININECQSS 827
Query: 2262 Q----MECKNLIGTYMCICGPGYQ----RRPDGEGCV--------------DENECQTKP 2299
C + I Y C+C PG+ + G C+ D N CQ
Sbjct: 828 PCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQ--- 884
Query: 2300 GICENGRCLNTR---GSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRN 2356
C NGR ++ G C + G + P+ C+ + CF + + SS+
Sbjct: 885 --CLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQ 942
Query: 2357 PVTKSECCCD 2366
PV K++C D
Sbjct: 943 PV-KTKCTSD 951
Score = 188 bits (478), Expect = 6e-47
Identities = 215/834 (25%), Positives = 316/834 (37%), Gaps = 235/834 (28%)
Query: 50 HDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAP 109
H + K P C +Y GW+ G C I C G C+ P C C +
Sbjct: 242 HGSCKLPGDCRCQY------GWQ----GLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQ 291
Query: 110 SCGSRSIQHCNIR--CMNGGSCSDD-----HCLCQKGYIGTHCGQPVCESGCL-----NG 157
C + + +C C+NGG+CS+ C C +GY G +C + E CL N
Sbjct: 292 LC-DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNC--EIAEHACLSDPCHNR 348
Query: 158 GRCVAPN---RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVG 214
G C + C C+ G+TGP C + CQ ++G C
Sbjct: 349 GSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKC---------- 398
Query: 215 RAWGHPCEMCPAQPHPCRRGFIPNIRTG-ACQ-DVDECQAIPGLCQGGNCINTVGSFECK 272
+CP Q TG CQ D +EC+A P + +C N + S+ C
Sbjct: 399 --------VCPPQ------------WTGKTCQLDANECEAKPCV-NAKSCKNLIASYYCD 437
Query: 273 CPAGHKLNEVSQKCE-DIDECSTIPGICEG-GECTNTVSSYFCKCPPGFYTSPDGTRCI- 329
C G + Q C+ +I++C G C+ C + V+ Y C CPPG+ G C
Sbjct: 438 CLPGW----MGQNCDININDCL---GQCQNDASCRDLVNGYRCICPPGYA----GDHCER 486
Query: 330 DVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWS----------PGVTVAPEMCPI 379
D+ L G C N+ I + QC C G + P C
Sbjct: 487 DIDECASNPCLNGGHCQNE----INRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYN 542
Query: 380 RATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSR 439
RA++ F C P G+ +L +
Sbjct: 543 RASDYF---CKCPEDYEGKN--------------------------------CSHL---K 564
Query: 440 EPPRVLPVNVTDYCQL----------VRYLCQN-----GRC-IPTPGSCRCECNKGFQLD 483
+ R P V D C + VRY+ N G+C + G C+CNKGF
Sbjct: 565 DHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGT 624
Query: 484 LRGECIDVDECEKNPCA-GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQN----- 537
E ++++CE NPC GG CI+ SY C C G++ T +I++C QN
Sbjct: 625 YCHE--NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCET---NINDCSQNPCHNG 679
Query: 538 -------------------GRIC-------------NNGRCINTDGSFHCVCNAGFHVTR 565
G+ C N G C + +F C+C G+
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW---- 735
Query: 566 DGKNCEDMDECS-IRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYC-KDINECETPGI 622
+G C S + N C NG C+ SF C+CK G++ G C ++ N+C +P
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE----GPICAQNTNDC-SPHP 790
Query: 623 CMN-GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKS 681
C N G CV+ D YRCEC PG A G D R+ ++ S C G C+ + G
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFA-GPDCRININECQSSPCAFG---ATCVDEING----Y 842
Query: 682 ECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICEN 741
C C P + A+ Q + SG + GS I + A D C C N
Sbjct: 843 RCVCP-------------PGHSGAKCQEV--SGRPCITMGSVIPDGAKWDDDCNTCQCLN 887
Query: 742 LR--------GTYKCICNSGYEVDSTGKNCVDI--NECVLNSLLCDN-GQCRNT 784
R G C+ + G+ +G++C+ I ++C ++ C G+CR++
Sbjct: 888 GRIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHP--CTGVGECRSS 939
Score = 187 bits (474), Expect = 2e-46
Identities = 203/785 (25%), Positives = 301/785 (38%), Gaps = 194/785 (24%)
Query: 1894 ECERDACGNGTCRNTIGSF----NCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCIN 1949
EC R C G C GS +CRC +G+ + + CI C G +C
Sbjct: 228 ECNRAICRQG-CSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHG---ICNE----- 278
Query: 1950 TVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNLD-GSYRCICPPGYSLQ 2007
+QC C + G+ C D+N C GTC N Y+C CP GYS
Sbjct: 279 ---PWQCLCETNW----GGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGP 331
Query: 2008 NEKCEDIDE-CVEEPEICA-LGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKF 2065
N CE + C+ +P C G+C T F+C C G++ + D + C
Sbjct: 332 N--CEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCS--- 384
Query: 2066 EGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSA 2125
GG C N K C + G C+L
Sbjct: 385 HGGTCQDLV--NGFK----CVCPPQWTGKTCQL--------------------------- 411
Query: 2126 VDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC-VDTDECSVGNPCGNGTCKNV 2184
D +EC+ C N SY C+C G++ G C ++ ++C +G + +C+++
Sbjct: 412 -DANECEAKPCVNAKSCKNLIASYYCDCLPGWM--GQNCDININDC-LGQCQNDASCRDL 467
Query: 2185 IGGFECTCEEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRR 2243
+ G+ C C G+ CE DI+ECA NP L C N ++C CP G+
Sbjct: 468 VNGYRCICPPGYAGDH---CERDIDECASNPCLNGGHCQNEINRFQCLCPTGF----SGN 520
Query: 2244 MCK-DEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVD-ENECQTKP-- 2299
+C+ D D CE + +C N Y C C Y +G+ C ++ C+T P
Sbjct: 521 LCQLDIDYCEPNP---CQNGAQCYNRASDYFCKCPEDY----EGKNCSHLKDHCRTTPCE 573
Query: 2300 -----------------------GIC-ENGRCLN-TRGSYTCECNDGFTAS---PNQDEC 2331
+C +G+C + + G +TC+CN GFT + N ++C
Sbjct: 574 VIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 2332 LDN--REG---------------------YCFTEV---LQNMCQIGSSNRNPVTKSECCC 2365
N R G YC T + QN C G + R+ V ++ C
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV--NDFYC 691
Query: 2366 DGGRGW-GPHCE---------ICPFQGTV-----AFKKLCPHG-RGFMTNGADIDECKVI 2409
D GW G C C GT AFK +CP G G N A C +
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSC--L 749
Query: 2410 HDVCRN-GECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC--NFICKNTEGSY 2466
+ C N G CV + S+ C+CK G+ I + N+C +P PC + C + + Y
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQ---NTNDC--SPHPCYNSGTCVDGDNWY 804
Query: 2467 QCSCPKGYILQEDGRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDN 2525
+C C G+ G C+ +++EC + CV+ I G+ C CPPG + +
Sbjct: 805 RCECAPGFA----GPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSG 860
Query: 2526 NECTS-------------DINLC----GSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2568
C + D N C G + G C +G S +G SC +
Sbjct: 861 RPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPI 920
Query: 2569 --DEC 2571
D+C
Sbjct: 921 LDDQC 925
Score = 175 bits (443), Expect = 7e-43
Identities = 214/859 (24%), Positives = 310/859 (36%), Gaps = 229/859 (26%)
Query: 94 CSRPNMCTCPSGQIAPSCGSRSIQHCNIRCM-NGGSCS-DDHCLCQKGYIGTHCGQPVCE 151
C + TC G + P C +R+I C C GSC C CQ G+ G +C + +
Sbjct: 212 CDQNGNKTCMEGWMGPEC-NRAI--CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPH 268
Query: 152 SGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKT---- 207
GC++ G C P +C C + G C++D C T +Q C L+G C+ T
Sbjct: 269 PGCVH-GICNEPWQCLCETNWGGQLCDKDLNY--CGT---HQPC---LNGGTCSNTGPDK 319
Query: 208 -LCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVD---ECQAIPG-------- 255
C G + G CE+ H C P G+C++ EC+ PG
Sbjct: 320 YQCSCPEGYS-GPNCEIA---EHACLSD--PCHNRGSCKETSLGFECECSPGWTGPTCST 373
Query: 256 ---------LCQGGNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECT 305
GG C + V F+C CP + C+ D +EC P + C
Sbjct: 374 NIDDCSPNNCSHGGTCQDLVNGFKCVCPP----QWTGKTCQLDANECEAKPCV-NAKSCK 428
Query: 306 NTVSSYFCKCPPGFYTS----------------------PDGTRCIDVRPGYC------- 336
N ++SY+C C PG+ +G RCI PGY
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCI-CPPGYAGDHCERD 487
Query: 337 ------YTALTNGRCSNQLPQSITKMQCCCDAGRCWS----------PGVTVAPEMCPIR 380
L G C N+ I + QC C G + P C R
Sbjct: 488 IDECASNPCLNGGHCQNE----INRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNR 543
Query: 381 ATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSRE 440
A++ F C P G+ +L ++
Sbjct: 544 ASDYF---CKCPEDYEGK--------------------------------NCSHL---KD 565
Query: 441 PPRVLPVNVTDYCQL----------VRYLCQN-----GRC-IPTPGSCRCECNKGFQLDL 484
R P V D C + VRY+ N G+C + G C+CNKGF
Sbjct: 566 HCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTY 625
Query: 485 RGECIDVDECEKNPCA-GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNN 543
E ++++CE NPC GG CI+ SY C C G++ T +I++C QN C+N
Sbjct: 626 CHE--NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCET---NINDCSQNP--CHN 678
Query: 544 -GRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLN-GMCINEDGSFKCICKPG 601
G C + F+C C G+ GK C D C N G C +E +FKC+C G
Sbjct: 679 GGTCRDLVNDFYCDCKNGW----KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG 734
Query: 602 FQLASDGRYCKDI-NECETPGICMN-GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRS 659
+ +G C N P C N G CV S+ C C G +G +C
Sbjct: 735 W----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC----KEGWEGPICAQNTNDC 786
Query: 660 TCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTS 719
+ + Y G C+ Y+ C+ G
Sbjct: 787 SPHPCYNSGTCV------------------------------DGDNWYRCECAPGFAGPD 816
Query: 720 AGSDINECALDPDICPNG-ICENLRGTYKCICNSGYE----VDSTGKNCVDINECVLNSL 774
+INEC P C G C + Y+C+C G+ + +G+ C+ + + +
Sbjct: 817 CRININECQSSP--CAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGA 874
Query: 775 L----CDNGQCRNTPGSFVCT---C-PKGFIYKPDLKTCEDIDECESSPCINGVCKNSPG 826
C+ QC N G C+ C P+ + C C P ++ C P
Sbjct: 875 KWDDDCNTCQCLN--GRIACSKVWCGPRPCLLHKGHSECPSGQSC--IPILDDQCFVHPC 930
Query: 827 SFICECSSESTLDPTKTIC 845
+ + EC S S+L P KT C
Sbjct: 931 TGVGECRS-SSLQPVKTKC 948
Score = 165 bits (418), Expect = 5e-40
Identities = 220/852 (25%), Positives = 297/852 (34%), Gaps = 228/852 (26%)
Query: 464 RCIPTPG----------SCRCECNKGFQLDLRGECIDVDECEKN-PCAGGECINNQG--S 510
+CIP PG C CE N G QL + D++ C + PC G +N G
Sbjct: 264 KCIPHPGCVHGICNEPWQCLCETNWGGQLCDK----DLNYCGTHQPCLNGGTCSNTGPDK 319
Query: 511 YTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNC 570
Y C C GY C + + N G C T F C C+ G+ G C
Sbjct: 320 YQCSCPEGYSGP----NCEIAEHACLSDPCHNRGSCKETSLGFECECSPGW----TGPTC 371
Query: 571 E-DMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK-DINECETPGICMNGR- 627
++D+CS N G C + FKC+C P + G+ C+ D NECE C+N +
Sbjct: 372 STNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQW----TGKTCQLDANECEAKP-CVNAKS 426
Query: 628 CVNTDGSYRCECFPG-------------LAVGLDGRVCVD--THMRSTCYGGYKRGQCIK 672
C N SY C+C PG L + C D R C GY C +
Sbjct: 427 CKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCER 486
Query: 673 PLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPD 732
+ CAS G CQ +Q LC +G DI+ C +P+
Sbjct: 487 DIDE--------CASNPCLNGGHCQ----NEINRFQCLCPTGFSGNLCQLDIDYC--EPN 532
Query: 733 ICPNGI-CENLRGTYKCICNSGYEVDSTGKNCVD------------INECV--------- 770
C NG C N Y C C YE GKNC I+ C
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDYE----GKNCSHLKDHCRTTPCEVIDSCTVAMASNDTP 588
Query: 771 -----LNSLLC-DNGQCRN-TPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCIN-GVCK 822
++S +C +G+C++ + G F C C KGF E+I++CES+PC N G C
Sbjct: 589 EGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF---TGTYCHENINDCESNPCRNGGTCI 645
Query: 823 NSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAA 882
+ S+ C CS W+ CE NIN CS
Sbjct: 646 DGVNSYKCICSDG------------------WE---GAYCETNIND-------CSQNPCH 677
Query: 883 WGSPCTLCQVDPICG--KGYSRIKGTQCEDID-ECEVFPGVCKN-GLCVNTRGSFKCQCP 938
G C D C G+ KG C D +C+ C N G C + +FKC CP
Sbjct: 678 NGGTCRDLVNDFYCDCKNGW---KGKTCHSRDSQCD--EATCNNGGTCYDEGDAFKCMCP 732
Query: 939 SGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPM 998
G G C R +C T + G C C G W C +
Sbjct: 733 GGW----EGTTCNIARNSSCLPNPCHNGGTCVVNG--ESFTCVCKEG--WEGPICAQ--- 781
Query: 999 RNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSG 1058
+ N+C P G C + ++C C G
Sbjct: 782 -----------------------------NTNDCSPHPCY-NSGTCVDGDNWYRCECAPG 811
Query: 1059 FALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQ 1118
FA N I+EC+ SP G CV+ + C C G+ C ++
Sbjct: 812 FAGPDCRIN---INECQSSPCAFG-ATCVDEINGYRCVCPPGHSGA-----KCQEV---S 859
Query: 1119 RDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGR--CVNL-I 1175
P + G V P G + D N C+ C NGR C +
Sbjct: 860 GRPCITMGSV-----------IPDGAKWDD------DCNTCQ-----CLNGRIACSKVWC 897
Query: 1176 GKYQCACNPGYHSTPDRLFCVDI--DECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQ 1233
G C + G+ P C+ I D+C + CT G EC +L P +
Sbjct: 898 GPRPCLLHKGHSECPSGQSCIPILDDQCFVHP------CT---GVGECRSS---SLQPVK 945
Query: 1234 RSCTDIDECEDN 1245
CT +DN
Sbjct: 946 TKCTSDSYYQDN 957
Score = 154 bits (388), Expect = 2e-36
Identities = 171/655 (26%), Positives = 257/655 (39%), Gaps = 133/655 (20%)
Query: 489 IDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQSTLTRTECR-DIDECLQNGRICNNGRC 546
+D +ECE PC + C N SY C C G+ C +I++CL G+ N+ C
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQ----NCDININDCL--GQCQNDASC 464
Query: 547 INTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLNG-MCINEDGSFKCICKPGFQL 604
+ + C+C G+ G +CE D+DEC+ N CLNG C NE F+C+C GF
Sbjct: 465 RDLVNGYRCICPPGYA----GDHCERDIDECA-SNPCLNGGHCQNEINRFQCLCPTGF-- 517
Query: 605 ASDGRYCK-DINECETPGICMNG-RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCY 662
G C+ DI+ CE P C NG +C N Y C+C +G+ C +H++ C
Sbjct: 518 --SGNLCQLDIDYCE-PNPCQNGAQCYNRASDYFCKC----PEDYEGKNC--SHLKDHC- 567
Query: 663 GGYKRGQC-IKPLFGAVTKSECCCASTEYAFGEPCQP---CPAQNSAEYQALCSSGPGMT 718
+ C + S Y C P C +Q+ ++ C+ G T
Sbjct: 568 ---RTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGT 624
Query: 719 SAGSDINECALDPDICPN-GICENLRGTYKCICNSGYEVDSTGKNC-VDINECVLNSLLC 776
+IN+C +P C N G C + +YKCIC+ G+E G C +IN+C N C
Sbjct: 625 YCHENINDCESNP--CRNGGTCIDGVNSYKCICSDGWE----GAYCETNINDCSQNP--C 676
Query: 777 DN-GQCRNTPGSFVCTCPKGFIYKPDLKTCEDID-ECESSPCIN-GVCKNSPGSFICECS 833
N G CR+ F C C G+ KTC D +C+ + C N G C + +F C C
Sbjct: 677 HNGGTCRDLVNDFYCDCKNGW----KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCP 732
Query: 834 SESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQC-----CSSLGAAWGSPCT 888
W+ C I N + L + C C G ++ C
Sbjct: 733 GG------------------WEGT---TCNIARNSSCLPNPCHNGGTCVVNGESFTCVCK 771
Query: 889 LCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATG 947
PIC ++ ++C P C N G CV+ ++C+C G G
Sbjct: 772 EGWEGPIC-----------AQNTNDCSPHP--CYNSGTCVDGDNWYRCECAPGF----AG 814
Query: 948 RICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEEL 1007
C I + C + C ++ C +C+E R +
Sbjct: 815 PDC-RININEC----QSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSV 869
Query: 1008 CPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGK--CRNT-IGSFKCRCDSGFALDSE 1064
P +G + D N C+ C +G+ C G C G +
Sbjct: 870 IP-----------DGAKWDDDCNTCQ-----CLNGRIACSKVWCGPRPCLLHKGHSECPS 913
Query: 1065 ERNCTDI--DECRISPDLCGRGQCVNT---PGDFECKCDEGYESGFMMMKNCMDI 1114
++C I D+C + P G G+C ++ P +C D Y+ NC +I
Sbjct: 914 GQSCIPILDDQCFVHP-CTGVGECRSSSLQPVKTKCTSDSYYQD------NCANI 961
Score = 122 bits (307), Expect = 4e-27
Identities = 140/564 (24%), Positives = 210/564 (37%), Gaps = 161/564 (28%)
Query: 457 RYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINNQGSYTCQC 515
R L RCI PG C + D+DEC NPC GG C N + C C
Sbjct: 465 RDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNEINRFQCLC 513
Query: 516 RAGYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHCVCNAGFHVTRDGKN----- 569
G+ L + DID C N C NG +C N + C C + +GKN
Sbjct: 514 PTGFSGNLCQL---DIDYCEPNP--CQNGAQCYNRASDYFCKCPEDY----EGKNCSHLK 564
Query: 570 -------CEDMDECSI---------------RNMC-LNGMCINED-GSFKCICKPGFQLA 605
CE +D C++ N+C +G C ++ G F C C GF
Sbjct: 565 DHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF--- 621
Query: 606 SDGRYC-KDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVC---VDTHMRSTC 661
G YC ++IN+CE+ G C++ SY+C C + G +G C ++ ++ C
Sbjct: 622 -TGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC----SDGWEGAYCETNINDCSQNPC 676
Query: 662 YGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAG 721
+ G G C V C C + G + C +++S +A C++G
Sbjct: 677 HNG---GTC----RDLVNDFYCDCKN-----GWKGKTCHSRDSQCDEATCNNG------- 717
Query: 722 SDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDN-GQ 780
G C + +KC+C G+E T N + C+ N C N G
Sbjct: 718 ---------------GTCYDEGDAFKCMCPGGWE--GTTCNIARNSSCLPNP--CHNGGT 758
Query: 781 CRNTPGSFVCTCPKGFIYKPDLKTC-EDIDECESSPCIN-GVCKNSPGSFICECSSESTL 838
C SF C C +G+ + C ++ ++C PC N G C + + CEC+
Sbjct: 759 CVVNGESFTCVCKEGW----EGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA----- 809
Query: 839 DPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCT--LCQVDPIC 896
C ININ C S A+G+ C + +C
Sbjct: 810 ----------------PGFAGPDCRININE-------CQSSPCAFGATCVDEINGYRCVC 846
Query: 897 GKGYSRIKGTQCEDID--ECEVFPGV----------CKNGLCVNTR--------GSFKCQ 936
G+S G +C+++ C V C C+N R G C
Sbjct: 847 PPGHS---GAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCL 903
Query: 937 CPSGMTLDATGRICLDIRLETCFL 960
G + +G+ C+ I + CF+
Sbjct: 904 LHKGHSECPSGQSCIPILDDQCFV 927
Score = 86.7 bits (213), Expect = 3e-16
Identities = 87/341 (25%), Positives = 125/341 (36%), Gaps = 80/341 (23%)
Query: 63 YNAYCCPGWKTLPGGNQCIVPI---CRHSCGDGFCSRPNM----CTCPSGQIAPSCGSRS 115
Y C GW+ G C I ++ C +G R + C C +G +C SR
Sbjct: 651 YKCICSDGWE----GAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRD 706
Query: 116 IQHCNIRCMNGGSCSDD----HCLCQKGYIGTHC----GQPVCESGCLNGGRCVAPNR-- 165
Q C NGG+C D+ C+C G+ GT C + C NGG CV
Sbjct: 707 SQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESF 766
Query: 166 -CACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMC 224
C C G+ GP C ++ T C S C + C G W + CE
Sbjct: 767 TCVCKEGWEGPICAQN--TNDC-------------SPHPCYNSGTCVD-GDNW-YRCECA 809
Query: 225 PAQPHP-CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVS 283
P P CR +++ECQ+ P G C++ + + C CP GH
Sbjct: 810 PGFAGPDCR------------ININECQSSP-CAFGATCVDEINGYRCVCPPGHS----G 852
Query: 284 QKCEDID--ECSTIPGI----------CEGGECTN---TVSSYFCKCPP-----GFYTSP 323
KC+++ C T+ + C +C N S +C P G P
Sbjct: 853 AKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECP 912
Query: 324 DGTRCIDVRPGYCYT--ALTNGRCSNQLPQSITKMQCCCDA 362
G CI + C+ G C + Q + K +C D+
Sbjct: 913 SGQSCIPILDDQCFVHPCTGVGECRSSSLQPV-KTKCTSDS 952
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.485
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 148,685,025
Number of Sequences: 37866
Number of extensions: 8944505
Number of successful extensions: 80605
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 349
Number of HSP's successfully gapped in prelim test: 528
Number of HSP's that attempted gapping in prelim test: 22129
Number of HSP's gapped (non-prelim): 16910
length of query: 2871
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2751
effective length of database: 13,703,598
effective search space: 37698598098
effective search space used: 37698598098
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.