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Search of human proteins with 24429574
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
(456 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24429574 solute carrier family 38, member 6 [Homo sapiens] 902 0.0
gi|5870893 solute carrier family 38, member 3 [Homo sapiens] 397 e-110
gi|21361602 solute carrier family 38, member 2 [Homo sapiens] 379 e-105
gi|219689132 solute carrier family 38, member 4 [Homo sapiens] 375 e-104
gi|18482385 solute carrier family 38, member 4 [Homo sapiens] 375 e-104
gi|193788624 solute carrier family 38, member 5 [Homo sapiens] 365 e-101
gi|117168277 amino acid transporter system A1 [Homo sapiens] 348 4e-96
gi|117168275 amino acid transporter system A1 [Homo sapiens] 348 4e-96
gi|8922692 solute carrier family 38, member 7 [Homo sapiens] 130 2e-30
gi|122937281 solute carrier family 38, member 8 [Homo sapiens] 105 7e-23
gi|27735137 solute carrier family 38, member 11 [Homo sapiens] 97 3e-20
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 94 2e-19
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ... 94 2e-19
gi|40807351 solute carrier family 36 (proton/amino acid symporte... 80 5e-15
gi|222418629 solute carrier family 38, member 9 [Homo sapiens] 67 3e-11
gi|222418631 solute carrier family 36, member 2 [Homo sapiens] 64 2e-10
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ... 61 2e-09
gi|17999520 solute carrier family 32, member 1 [Homo sapiens] 61 2e-09
gi|41352721 solute carrier family 36 member 1 [Homo sapiens] 54 3e-07
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ... 39 0.007
gi|7657373 tetraspan NET-6 [Homo sapiens] 33 0.70
gi|225637489 hypothetical protein LOC54777 [Homo sapiens] 32 1.6
gi|52693931 olfactory receptor, family 4, subfamily F, member 6 ... 32 1.6
gi|4557311 adenosine monophosphate deaminase 1 (isoform M) [Homo... 30 3.5
gi|52353280 olfactory receptor, family 6, subfamily Y, member 1 ... 30 5.9
gi|153252029 C-type lectin domain family 1, member B isoform a [... 29 7.7
>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
Length = 456
Score = 902 bits (2330), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MEASWGSFNAERGWYVSVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMG 60
MEASWGSFNAERGWYVSVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMG
Sbjct: 1 MEASWGSFNAERGWYVSVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMG 60
Query: 61 SGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPG 120
SGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPG
Sbjct: 61 SGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPG 120
Query: 121 KLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVF 180
KLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVF
Sbjct: 121 KLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVF 180
Query: 181 PLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKP 240
PLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKP
Sbjct: 181 PLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKP 240
Query: 241 KLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISA 300
KLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISA
Sbjct: 241 KLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISA 300
Query: 301 LFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFF 360
LFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFF
Sbjct: 301 LFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFF 360
Query: 361 SNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSR 420
SNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSR
Sbjct: 361 SNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSR 420
Query: 421 EDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWINK 456
EDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWINK
Sbjct: 421 EDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWINK 456
>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
Length = 504
Score = 397 bits (1020), Expect = e-110
Identities = 207/427 (48%), Positives = 282/427 (66%), Gaps = 19/427 (4%)
Query: 46 SFGLSVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAV 105
SFG+SVFNL NAIMGSGILGLAY MANTG+ F FLL VALL+SYS+HLLL +
Sbjct: 67 SFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGI 126
Query: 106 TSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLT-GDYSRYWY 164
+YE LG AFG PGKL A I +QNIGAMSSYL IIK+ELP I FL + + WY
Sbjct: 127 RAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWY 186
Query: 165 LDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNY 224
++G L+I++ V I+ PLAL+ ++G+LGY+S S M+FF + VI KK+ +PCPL N+
Sbjct: 187 MNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNF 246
Query: 225 VEKGFQISNV---------------TDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPI 269
S+V + C P F + ++AY +P MAF+F+CH +LPI
Sbjct: 247 NNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPI 306
Query: 270 YCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVV 329
Y EL+ PSKK+MQ+++N +IA+ +++YF++ALFGYLTFY+ VESELL YSK DV++
Sbjct: 307 YTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLI 366
Query: 330 MTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVP 389
+ V++ +L AV LTVP++ FP R+A+ M F N FSW+RH LI + L I LL I+ P
Sbjct: 367 LCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAP 426
Query: 390 DIRNVFGVVGASTSTCLIFIFPGLFYLKL---SREDFLSWKKLGAFVLLIFGILVGNFSL 446
+I +FGV+GA+++ LIFIFP +FY ++ +E S K+ A + G L+ SL
Sbjct: 427 NILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSL 486
Query: 447 ALIIFDW 453
+ II DW
Sbjct: 487 SFIIIDW 493
>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
Length = 506
Score = 379 bits (972), Expect = e-105
Identities = 205/458 (44%), Positives = 294/458 (64%), Gaps = 26/458 (5%)
Query: 23 EAEAEELSPLLSNELHRQR-----SPGV-SFGLSVFNLMNAIMGSGILGLAYVMANTGVF 76
+ + E + LL + L +++ PG SFG+SVFNL NAI+GSGILGL+Y MANTG+
Sbjct: 43 DVDPENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIA 102
Query: 77 GFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAM 136
F LL V++ + YSVHLLL + YE LG AFGL GKL +G+I +QNIGAM
Sbjct: 103 LFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAM 162
Query: 137 SSYLLIIKTELPAAIAEFLTG--DYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYT 194
SSYL I+K ELP I + LT D + WYL+G L++++ + ++ PL+L +G+LGYT
Sbjct: 163 SSYLFIVKYELPLVI-QALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYT 221
Query: 195 SSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVT----------------DDC 238
S LS M+FF +VVI KK+ +PCP+ + + +T D C
Sbjct: 222 SGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTENDSC 281
Query: 239 KPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFI 298
+P F F+ ++ YA+P + FSF+CH ++LPIY EL+ S++RM NV+ + FL+Y +
Sbjct: 282 RPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLL 341
Query: 299 SALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMM 358
+ALFGYLTFY+ VESELL YS L D++++ V+L +L AV LTVP++ FP R +VT +
Sbjct: 342 AALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHL 401
Query: 359 FFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKL 418
++ FSW RH LIT+++ LL I+VP IR++FG +GAS ++ LIFI P FY+KL
Sbjct: 402 LCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKL 461
Query: 419 -SREDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWIN 455
+E S +K+GA L+ G+LV S+ALI+ DW++
Sbjct: 462 VKKEPMKSVQKIGALFFLLSGVLVMTGSMALIVLDWVH 499
>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 375 bits (963), Expect = e-104
Identities = 214/474 (45%), Positives = 285/474 (60%), Gaps = 63/474 (13%)
Query: 40 QRSPGV-SFGLSVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLS 98
+ PG SFG+S FNL NAIMGSGILGL+Y MANTG+ F +LL VA+L+ YSVHLLL
Sbjct: 69 EHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLK 128
Query: 99 MCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFL--- 155
+ YE LG AFG PGK+ +I +QNIGAMSSYL IIK ELP I F+
Sbjct: 129 TAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLE 188
Query: 156 --TGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKK 213
TG+ WYL+G L+I + VGI+ PL+LL +G+LGYTS S M+FF VVI KK
Sbjct: 189 ENTGE----WYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKK 244
Query: 214 WSIPCPLTL------------------------------NYV------------------ 225
+ IPCPL + N++
Sbjct: 245 FQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKG 304
Query: 226 ---EKGFQISNVTDD-CKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRM 281
+ G + +DD C+PK F F+ +AYA+P + F+F+CH +LPIY EL+ S+++M
Sbjct: 305 SLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKM 364
Query: 282 QNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVL 341
Q V+N +I ++Y ++ALFGYLTFY +VE ELL YSK + D+ ++ V+L +L AV
Sbjct: 365 QTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVT 424
Query: 342 LTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGAS 401
LTVP++ FP R +V + F PFSWIRHFLI L + +L I VP I+ +FG +GAS
Sbjct: 425 LTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGAS 484
Query: 402 TSTCLIFIFPGLFYLKL-SREDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWI 454
++T LIFI P +FYLKL +E F S +K+GA + L+ GI S+ALII DWI
Sbjct: 485 SATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWI 538
>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 375 bits (963), Expect = e-104
Identities = 214/474 (45%), Positives = 285/474 (60%), Gaps = 63/474 (13%)
Query: 40 QRSPGV-SFGLSVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLS 98
+ PG SFG+S FNL NAIMGSGILGL+Y MANTG+ F +LL VA+L+ YSVHLLL
Sbjct: 69 EHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLK 128
Query: 99 MCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFL--- 155
+ YE LG AFG PGK+ +I +QNIGAMSSYL IIK ELP I F+
Sbjct: 129 TAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLE 188
Query: 156 --TGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKK 213
TG+ WYL+G L+I + VGI+ PL+LL +G+LGYTS S M+FF VVI KK
Sbjct: 189 ENTGE----WYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKK 244
Query: 214 WSIPCPLTL------------------------------NYV------------------ 225
+ IPCPL + N++
Sbjct: 245 FQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKG 304
Query: 226 ---EKGFQISNVTDD-CKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRM 281
+ G + +DD C+PK F F+ +AYA+P + F+F+CH +LPIY EL+ S+++M
Sbjct: 305 SLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKM 364
Query: 282 QNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVL 341
Q V+N +I ++Y ++ALFGYLTFY +VE ELL YSK + D+ ++ V+L +L AV
Sbjct: 365 QTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVT 424
Query: 342 LTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGAS 401
LTVP++ FP R +V + F PFSWIRHFLI L + +L I VP I+ +FG +GAS
Sbjct: 425 LTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGAS 484
Query: 402 TSTCLIFIFPGLFYLKL-SREDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWI 454
++T LIFI P +FYLKL +E F S +K+GA + L+ GI S+ALII DWI
Sbjct: 485 SATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWI 538
>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
Length = 472
Score = 365 bits (938), Expect = e-101
Identities = 194/417 (46%), Positives = 266/417 (63%), Gaps = 12/417 (2%)
Query: 46 SFGLSVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAV 105
SFG+SVFNL NAIMGSGILGLAY MA+TGV F LLL +ALL+SYS+HLLL+ +
Sbjct: 49 SFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGI 108
Query: 106 TSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYL 165
+YE LG AFG GK+VVA I + N+GAMSSYL IIK+ELP I FL D W+L
Sbjct: 109 RAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFL 168
Query: 166 DGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYV 225
G L+II+ V I+ PLAL+ +G+LGYTS LS M+FF + VI KK+ + C + N
Sbjct: 169 KGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNET 228
Query: 226 EK------GFQISNVTDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKK 279
G + C+ ++F + +Y +P MAF+F+CH +LPIY EL PSK+
Sbjct: 229 AMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKR 288
Query: 280 RMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFA 339
RMQ V N +I F +Y ++A FGYLTFY V++E+L YS+ D +++ V+L +L A
Sbjct: 289 RMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQ---KDPLILCVRLAVLLA 345
Query: 340 VLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVG 399
V LTVP++ FP R+A+ + F FSW RH I L L +++ +L I VP IR++FGV+G
Sbjct: 346 VTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIG 405
Query: 400 ASTSTCLIFIFPGLFYLKL---SREDFLSWKKLGAFVLLIFGILVGNFSLALIIFDW 453
++++ LIFI P +FYL++ E FLSW K+ A + G+L SL + +W
Sbjct: 406 STSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANW 462
>gi|117168277 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 348 bits (894), Expect = 4e-96
Identities = 191/439 (43%), Positives = 281/439 (64%), Gaps = 15/439 (3%)
Query: 24 AEAEELSPLLSNELHRQRS----PGV-SFGLSVFNLMNAIMGSGILGLAYVMANTGVFGF 78
++ E L ++ L +++ PG S G+SVFNL NAIMGSGILGLA+ +ANTG+ F
Sbjct: 45 SDRESRRSLTNSHLEKKKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLF 104
Query: 79 SFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSS 138
LL +V LL+ YS++LLL +T YE LG FG GK V+ G +QN GAM S
Sbjct: 105 LVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLS 164
Query: 139 YLLIIKTELPAAIAEFLTGDYSRY--WYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSS 196
YL I+K ELP+AI +FL G + WY+DG+ L++I+ GI+ PL LL +G+LGYTS
Sbjct: 165 YLFIVKNELPSAI-KFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSG 223
Query: 197 LSFFFMMFFALVVIIKKWSIPCPL-TLNYVEKGFQISNVTDDCKPKLFHFSKESAYALPT 255
S M+FF +VVI KK+ IPC + LN S D C PK F+ ++ YALPT
Sbjct: 224 FSLSCMVFFLIVVIYKKFQIPCIVPELNSTISA--NSTNADTCTPKYVTFNSKTVYALPT 281
Query: 256 MAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESEL 315
+AF+F+CH S+LPIY EL+ S+K+MQ V+N + F++YF++A+FGYLTFYD V+S+L
Sbjct: 282 IAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDL 341
Query: 316 LKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITL 375
L Y D++++TV+L ++ AV+LTVP++ F R ++ F+ RH ++T
Sbjct: 342 LHKYQS--KDDILILTVRLAVIVAVILTVPVLFFTVRSSL-FELAKKTKFNLCRHTVVTC 398
Query: 376 ALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSRED-FLSWKKLGAFVL 434
L ++I LL I++P ++++FGVVG +++ LIFI P YLK++ +D +++ A +
Sbjct: 399 ILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWAALF 458
Query: 435 LIFGILVGNFSLALIIFDW 453
L G+L S+ L+I+DW
Sbjct: 459 LGLGVLFSLVSIPLVIYDW 477
>gi|117168275 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 348 bits (894), Expect = 4e-96
Identities = 191/439 (43%), Positives = 281/439 (64%), Gaps = 15/439 (3%)
Query: 24 AEAEELSPLLSNELHRQRS----PGV-SFGLSVFNLMNAIMGSGILGLAYVMANTGVFGF 78
++ E L ++ L +++ PG S G+SVFNL NAIMGSGILGLA+ +ANTG+ F
Sbjct: 45 SDRESRRSLTNSHLEKKKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLF 104
Query: 79 SFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSS 138
LL +V LL+ YS++LLL +T YE LG FG GK V+ G +QN GAM S
Sbjct: 105 LVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLS 164
Query: 139 YLLIIKTELPAAIAEFLTGDYSRY--WYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSS 196
YL I+K ELP+AI +FL G + WY+DG+ L++I+ GI+ PL LL +G+LGYTS
Sbjct: 165 YLFIVKNELPSAI-KFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSG 223
Query: 197 LSFFFMMFFALVVIIKKWSIPCPL-TLNYVEKGFQISNVTDDCKPKLFHFSKESAYALPT 255
S M+FF +VVI KK+ IPC + LN S D C PK F+ ++ YALPT
Sbjct: 224 FSLSCMVFFLIVVIYKKFQIPCIVPELNSTISA--NSTNADTCTPKYVTFNSKTVYALPT 281
Query: 256 MAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESEL 315
+AF+F+CH S+LPIY EL+ S+K+MQ V+N + F++YF++A+FGYLTFYD V+S+L
Sbjct: 282 IAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDL 341
Query: 316 LKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITL 375
L Y D++++TV+L ++ AV+LTVP++ F R ++ F+ RH ++T
Sbjct: 342 LHKYQS--KDDILILTVRLAVIVAVILTVPVLFFTVRSSL-FELAKKTKFNLCRHTVVTC 398
Query: 376 ALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSRED-FLSWKKLGAFVL 434
L ++I LL I++P ++++FGVVG +++ LIFI P YLK++ +D +++ A +
Sbjct: 399 ILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWAALF 458
Query: 435 LIFGILVGNFSLALIIFDW 453
L G+L S+ L+I+DW
Sbjct: 459 LGLGVLFSLVSIPLVIYDW 477
>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
Length = 462
Score = 130 bits (327), Expect = 2e-30
Identities = 102/404 (25%), Positives = 187/404 (46%), Gaps = 31/404 (7%)
Query: 50 SVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTA-VTSY 108
++F ++NA +G+G+L + G L L+ S ++L+ C Q + +Y
Sbjct: 56 AIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTY 115
Query: 109 EDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLII---KTELPAAIAEFLTGDYSRYWYL 165
+++ G ++ I + G ++L+II + ++ A +A+ G S WY
Sbjct: 116 QEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGA-SGPWYT 174
Query: 166 DGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYV 225
D + + + + PL++ +IGF Y S LS + +VIIK +
Sbjct: 175 DRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIK---------YIWP 225
Query: 226 EKGFQISNVTDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVT 285
+K N+ + F+ A+PT+ F F CH S +P++ +Q P K V
Sbjct: 226 DKEMTPGNILTRPASWMAVFN-----AMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVV 280
Query: 286 NTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVP 345
A+ ++ +Y + + G+LTF V+ ++L Y S D+ V + I+ +VL + P
Sbjct: 281 TAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYP---SEDMAVAVARAFIILSVLTSYP 337
Query: 346 LIHFPARKAVTMMF--FSNFPF------SWIRHFLITLALNIIIVLLAIYVPDIRNVFGV 397
++HF R V ++ + P R L TL ++ +LLA+++PDI V V
Sbjct: 338 ILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISV 397
Query: 398 VGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGAFVLLIFGILV 441
+G + C IF+FPGL ++ + K +VL+ +G+L+
Sbjct: 398 IG-GLAACFIFVFPGLCLIQAKLSEMEEVKPASWWVLVSYGVLL 440
>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
Length = 435
Score = 105 bits (263), Expect = 7e-23
Identities = 89/382 (23%), Positives = 176/382 (46%), Gaps = 39/382 (10%)
Query: 50 SVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYE 109
+VF LM + +G+G+L + + G +FL+ V+L+ S ++L AV+
Sbjct: 29 AVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYA--AAVSGQA 86
Query: 110 DLGLFAFGLPGKLV--VAGTIIIQNIGAMS-SYLLIIKTELPAAIAEFLTGD--YSRYWY 164
GL G + + + N+ +S ++L +I +L L+G + WY
Sbjct: 87 TYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWY 146
Query: 165 LDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNY 224
D + L ++ V ++ PL+ +I F YTS L + ALV+ ++ + P
Sbjct: 147 ADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWP------- 199
Query: 225 VEKGFQISNVTDDCKPKLFHFSKESAYAL-PTMAFSFLCHTSILPIYCELQSPSKKRMQN 283
+ + P L S S +++ PT+ F F CH + + IYC ++ S
Sbjct: 200 -------QGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWAL 252
Query: 284 VTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLT 343
V+ ++ LIY ++ ++G+LTF +V +++L Y +D+V++ ++ +++
Sbjct: 253 VSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYP---GNDMVIIVARVLFAVSIVTV 309
Query: 344 VPLIHFPARKAVTMMF------------FSNFPFSWIRHFLITLALNIIIVLLAIYVPDI 391
P++ F R + + ++ W+R L L + + + +A+++PD+
Sbjct: 310 YPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLA-MALFMPDL 368
Query: 392 RNVFGVVGASTSTCLIFIFPGL 413
+ ++G S+ IFIFPGL
Sbjct: 369 SEIVSIIG-GISSFFIFIFPGL 389
>gi|27735137 solute carrier family 38, member 11 [Homo sapiens]
Length = 384
Score = 97.1 bits (240), Expect = 3e-20
Identities = 92/371 (24%), Positives = 161/371 (43%), Gaps = 44/371 (11%)
Query: 81 LLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYL 140
LL V+ + +S+ LL+ + +Y+ L FG PG L+++ ++Q + Y
Sbjct: 12 LLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLS---VLQFL-----YP 63
Query: 141 LIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFF 200
I+ E F+ G + V PL+L I LG S +S
Sbjct: 64 FIVDPENVFIGRHFIIG---------------LSTVTFTLPLSLYRNIAKLGKVSLISTG 108
Query: 201 FMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKPKLFHFSKESAY-ALPTMAFS 259
+V+ + S+ G I D + F+K +A A+ M+F+
Sbjct: 109 LTTLILGIVMARAISL-----------GPHIPKTED-----AWVFAKPNAIQAVGVMSFA 152
Query: 260 FLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGY 319
F+CH + +Y L+ P+ + + + +I +S I A GYLTF + +L + Y
Sbjct: 153 FICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTGFTQGDLFENY 212
Query: 320 SKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNI 379
+ +D +V + C V+LT P+ F R+ + +FF S + H ++T+ +
Sbjct: 213 CR---NDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFFGG-NLSSVFHIVVTVMVIT 268
Query: 380 IIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGAFVLLIFGI 439
+ L+++ + + V + G +T LIFI P YLKLS E K+ + V+L G
Sbjct: 269 VATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKLSEEPRTHSDKIMSCVMLPIGA 328
Query: 440 LVGNFSLALII 450
+V F + I
Sbjct: 329 VVMVFGFVMAI 339
>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
sapiens]
Length = 1119
Score = 94.4 bits (233), Expect = 2e-19
Identities = 81/402 (20%), Positives = 177/402 (44%), Gaps = 42/402 (10%)
Query: 51 VFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYED 110
+ N++N+I+G +L + + G+ + LL+ + + S L+ + +Y
Sbjct: 12 ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAG 71
Query: 111 LGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIK---TELPAAIAEFLTGDYSRYWYLDG 167
L A+G GK++V ++I +G ++ ++I + A + F G R +
Sbjct: 72 LAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVGGTFRMF---- 127
Query: 168 QTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEK 227
LL + + IV PL+L + + S S ++F+ + + + + L+ ++
Sbjct: 128 --LLFAVSLCIVLPLSL--QRNMMASIQSFSAMALLFYTVFMFV--------IVLSSLKH 175
Query: 228 GFQISNVTDDCKPKLFHFSKESAY-ALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTN 286
G + ++ + E + +P SF C + +LP Y L PS K M ++
Sbjct: 176 GL----FSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFA 231
Query: 287 TAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPL 346
+++ + Y + FGY++F + +L + ++V +++ + +V + P+
Sbjct: 232 SSLNVVTTFYVMVGFFGYVSFTEATAGNVL----MHFPSNLVTEMLRVGFMMSVAVGFPM 287
Query: 347 IHFPARKAVTMM----------FFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFG 396
+ P R+A++ + F + +R +TL++ ++ I +P++ + G
Sbjct: 288 MILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILG 347
Query: 397 VVGASTSTCLIFIFPGLFYLKLSREDFLS----WKKLGAFVL 434
+ GA+ + + FI P L Y K+ + S W LG V+
Sbjct: 348 LTGATMGSLICFICPALIYKKIHKNALSSQVVLWVGLGVLVV 389
>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
sapiens]
Length = 780
Score = 94.4 bits (233), Expect = 2e-19
Identities = 81/402 (20%), Positives = 177/402 (44%), Gaps = 42/402 (10%)
Query: 51 VFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYED 110
+ N++N+I+G +L + + G+ + LL+ + + S L+ + +Y
Sbjct: 12 ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAG 71
Query: 111 LGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIK---TELPAAIAEFLTGDYSRYWYLDG 167
L A+G GK++V ++I +G ++ ++I + A + F G R +
Sbjct: 72 LAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVGGTFRMF---- 127
Query: 168 QTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEK 227
LL + + IV PL+L + + S S ++F+ + + + + L+ ++
Sbjct: 128 --LLFAVSLCIVLPLSL--QRNMMASIQSFSAMALLFYTVFMFV--------IVLSSLKH 175
Query: 228 GFQISNVTDDCKPKLFHFSKESAY-ALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTN 286
G + ++ + E + +P SF C + +LP Y L PS K M ++
Sbjct: 176 GL----FSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFA 231
Query: 287 TAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPL 346
+++ + Y + FGY++F + +L + ++V +++ + +V + P+
Sbjct: 232 SSLNVVTTFYVMVGFFGYVSFTEATAGNVL----MHFPSNLVTEMLRVGFMMSVAVGFPM 287
Query: 347 IHFPARKAVTMM----------FFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFG 396
+ P R+A++ + F + +R +TL++ ++ I +P++ + G
Sbjct: 288 MILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILG 347
Query: 397 VVGASTSTCLIFIFPGLFYLKLSREDFLS----WKKLGAFVL 434
+ GA+ + + FI P L Y K+ + S W LG V+
Sbjct: 348 LTGATMGSLICFICPALIYKKIHKNALSSQVVLWVGLGVLVV 389
>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
member 4 [Homo sapiens]
Length = 504
Score = 79.7 bits (195), Expect = 5e-15
Identities = 103/453 (22%), Positives = 185/453 (40%), Gaps = 50/453 (11%)
Query: 22 EEAEAEELSPLLSN-ELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVMANTGVFGFSF 80
+E +EL P+ + +L Q G+SF ++ +L+ +G+G+LGL + N G+
Sbjct: 37 DEEHEQELLPVQKHYQLDDQE--GISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPI 94
Query: 81 LLLTVALLASYSVHLL------LSMCIQTAVTSYEDLGLFAFGLP-----------GKLV 123
L+ + +++ + +H+L L + + + Y D FA + G+ V
Sbjct: 95 SLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSV 154
Query: 124 VAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIIC----VGI- 178
V ++I +G S Y++ + + FL ++ T C V +
Sbjct: 155 VDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKV----FISNSTNSSNPCERRSVDLR 210
Query: 179 VFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDC 238
++ L LP I L + L F++ F V S+ L + Y + + N+ D
Sbjct: 211 IYMLCFLPFIILLVFIRELKNLFVLSFLANV-----SMAVSLVIIY---QYVVRNMPDPH 262
Query: 239 KPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFI 298
+ K+ T F+F +LP+ E Q KR N + + +Y
Sbjct: 263 NLPIVAGWKKYPLFFGTAVFAFEGIGVVLPL--ENQMKESKRFPQALNIGMGIVTTLYVT 320
Query: 299 SALFGYLTFYDKVESELLKGYSKYLSHDV-VVMTVKLCILFAVLLTVPLIHFPARKAVTM 357
A GY+ F+D+++ + + L DV + +VK+ F + +T + + + +
Sbjct: 321 LATLGYMCFHDEIKGSI----TLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIP 376
Query: 358 MFFSNFPFSW--IRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLF- 414
S F W I F I L I AI +P + V VGA +S+ L I P L
Sbjct: 377 GITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVE 436
Query: 415 YLKLSREDFLSW---KKLGAFVLLIFGILVGNF 444
L S+E + W K + + G L+G +
Sbjct: 437 ILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTY 469
>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
Length = 561
Score = 67.0 bits (162), Expect = 3e-11
Identities = 102/479 (21%), Positives = 184/479 (38%), Gaps = 115/479 (24%)
Query: 49 LSVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLS-----MCIQT 103
+++F + N +MG+ IL + + + G +++ + LL Y + ++ + T
Sbjct: 121 VTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLYCCYRVVKSRTMMFSLDT 180
Query: 104 AVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTEL---------------- 147
Y D+ FG G+ ++ IGAM Y +++ L
Sbjct: 181 TSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHIND 240
Query: 148 ---------------PAAIAE---------FLTGD-----YSRYWYLDGQTLLIIICVGI 178
P+A + F D + ++W D + VG+
Sbjct: 241 TDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQQFEKWW--DKSRTVPFYLVGL 298
Query: 179 VFPL------ALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQIS 232
+ PL + K LG S L F++ F V + GF +
Sbjct: 299 LLPLLNFKSPSFFSKFNILGTVSVLYLIFLVTFKAVRL-----------------GFHLE 341
Query: 233 NVTDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPI-------YCELQSPSKKRMQNVT 285
FH+ + + +P + F F T +L + L +KK+ NV
Sbjct: 342 ----------FHWFIPTEFFVPEIRFQFPQLTGVLTLAFFIHNCIITLLKNNKKQENNVR 391
Query: 286 NTAIA--LSFLIYFISALFGYLTF------YDKVESELLKGYSKYLSHDVVVMTVKLCIL 337
+ IA L L Y + + +F D +E L + S D + ++ +L
Sbjct: 392 DLCIAYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFP---SSDTLSFIARIFLL 448
Query: 338 FAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIV----LLAIYVPDIRN 393
F ++ PL+ + AR + F + + I H LI LN+IIV ++A + P+I
Sbjct: 449 FQMMTVYPLLGYLARVQLLGHIFGDI-YPSIFHVLI---LNLIIVGAGVIMACFYPNIGG 504
Query: 394 VFGVVGASTSTCLIFIFPGLFY-LKLSREDFLSWKKLGAFVLLIFGILVGNFSLALIIF 451
+ GA+ +FI+P L Y + L +E+ L+W KL + +F I++G +L + F
Sbjct: 505 IIRYSGAACGLAFVFIYPSLIYIISLHQEERLTWPKL---IFHVFIIILGVANLIVQFF 560
>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
Length = 483
Score = 64.3 bits (155), Expect = 2e-10
Identities = 86/451 (19%), Positives = 179/451 (39%), Gaps = 39/451 (8%)
Query: 17 SVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVMANTGVF 76
S ++ E ++ L S +++ G++ ++ +L+ MG+GILGL + N G+
Sbjct: 26 SAKKLENKDSTFLDESPSESAGLKKTKGITVFQALIHLVKGNMGTGILGLPLAVKNAGIL 85
Query: 77 GFSFLLLTVALLASYSVHLLLSMC------IQTAVTSYEDLGLFAFGLP----------- 119
LL + +A + +H+L+ + Y D +
Sbjct: 86 MGPLSLLVMGFIACHCMHILVKCAQRFCKRLNKPFMDYGDTVMHGLEANPNAWLQNHAHW 145
Query: 120 GKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIV 179
G+ +V+ +II +G Y++ + L + + Y + +L +
Sbjct: 146 GRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEA--VNSTTNNCYSNETVILTPTMDSRL 203
Query: 180 FPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCK 239
+ L+ LP + L +L + F+++ I + + + Y+ + + D +
Sbjct: 204 YMLSFLPFLVLLVLIRNLRI--LTIFSMLANISML-VSLVIIIQYITQ-----EIPDPSR 255
Query: 240 PKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFIS 299
L K T FSF +LP+ E + + + + + +++ +Y
Sbjct: 256 LPLVASWKTYPLFFGTAIFSFESIGVVLPL--ENKMKNARHFPAILSLGMSIVTSLYIGM 313
Query: 300 ALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMF 359
A GYL F D +++ + S L + + +VKL + +L T L + + +
Sbjct: 314 AALGYLRFGDDIKASI----SLNLPNCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFA 369
Query: 360 FSNFPFSWIRHFLITLALNIIIV--LLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLK 417
S W +++ L ++ + LLAI +P + V +VG+ + T L I P L +
Sbjct: 370 ISRVSTRWALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVT 429
Query: 418 LSREDFLS----WKKLGAFVLLIFGILVGNF 444
+ +S +K +L G +VG +
Sbjct: 430 TFYSEGMSPLTIFKDALISILGFVGFVVGTY 460
>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
sapiens]
Length = 470
Score = 61.2 bits (147), Expect = 2e-09
Identities = 91/447 (20%), Positives = 191/447 (42%), Gaps = 42/447 (9%)
Query: 17 SVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVMANTGVF 76
S+ ++ +E S + S +H G+S ++ +L+ +G+G+LGL + N G+
Sbjct: 14 SLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLL 73
Query: 77 GFSFLLLTVALLASYSVHLL------LSMCIQTAVTSYEDLGLF-----------AFGLP 119
LL + +L + + +L LS +Q +Y + ++ A +
Sbjct: 74 VGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVW 133
Query: 120 GKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAE-FLTGDYSRYWYLDGQTLLIIICVGI 178
G+ V+ ++I +G S Y + + L + + +T + + + TL I+ +
Sbjct: 134 GRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREI--LTLTPILDIRF 191
Query: 179 VFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQI-SNVTDD 237
+ L +LP + L + +L +F L I S+ L Y+ +G SN+
Sbjct: 192 -YMLIILPFLILLVFIQNLK-VLSVFSTLANITTLGSM--ALIFEYIMEGIPYPSNL--- 244
Query: 238 CKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYF 297
P + ++ K T F+F +LP+ +++ P ++ V +++ ++Y
Sbjct: 245 --PLMANW-KTFLLFFGTAIFTFEGVGMVLPLKNQMKHP--QQFSFVLYLGMSIVIILYI 299
Query: 298 ISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPL-IHFPARKAVT 356
+ GY+ F ++ + + L + + +VKL + T L H PA + +
Sbjct: 300 LLGTLGYMKFGSDTQASI----TLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPA-EIII 354
Query: 357 MMFFSNFPFSWIRHFLITL--ALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLF 414
S SW +++ AL + + AI +P + V +VG+ +S+ L I P L
Sbjct: 355 PFAISQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALL 414
Query: 415 YLKLSREDFLSWKKLGAFVLL-IFGIL 440
+ + + +S + +++ I G+L
Sbjct: 415 EIVIFYSEDMSCVTIAKDIMISIVGLL 441
>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
Length = 525
Score = 61.2 bits (147), Expect = 2e-09
Identities = 90/403 (22%), Positives = 166/403 (41%), Gaps = 65/403 (16%)
Query: 52 FNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDL 111
+N+ NAI G +LGL Y + + G G FL++ A++ Y+ +L++ + ED
Sbjct: 123 WNVTNAIQGMFVLGLPYAILHGGYLGL-FLIIFAAVVCCYTGKILIACLYE----ENED- 176
Query: 112 GLFAFGLPGKLVVAGTIIIQNI----GAMSSYLLIIKTELPAAIAEFLTGD--YSRYWYL 165
G + +A G + + II+ + + ++G+ Y+ + L
Sbjct: 177 GEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL 236
Query: 166 D-GQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLT--- 221
Q II ++ P A L + + K+S+ C L
Sbjct: 237 PVSQKSWSIIATAVLLPCAFLKNLK--------------------AVSKFSLLCTLAHFV 276
Query: 222 LNYVEKGFQISNVTDDC--KPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKK 279
+N + + +S D K K + K+ ++ + FS+ + + +Q PS+
Sbjct: 277 INILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEF 336
Query: 280 R-MQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILF 338
M N T+ A + + + AL YLT+ D+ + + + V + ++
Sbjct: 337 HCMMNWTHIAACV---LKGLFALVAYLTWADETKEVITDNLPGSIR-----AVVNIFLVA 388
Query: 339 AVLLTVPLIHFPARKAVTMMFFSN-----FPFSW-----IRHFLITL--ALNIIIVLLAI 386
LL+ PL F A + + F FP + ++ + +TL AL + +L+AI
Sbjct: 389 KALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAI 448
Query: 387 YVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKL 429
YVP + G+ G+ T L F+ P LF+L+ L W+KL
Sbjct: 449 YVPHFALLMGLTGSLTGAGLCFLLPSLFHLR------LLWRKL 485
>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
Length = 476
Score = 53.9 bits (128), Expect = 3e-07
Identities = 87/450 (19%), Positives = 181/450 (40%), Gaps = 43/450 (9%)
Query: 21 PEEAEAEELSPLLSNELHRQ--RSPGVSFGLSVFNLMNAIMGSGILGLAYVMANTGVFGF 78
PEE+ +E L+ L S +++ +S ++ ++ +L+ +G+G+LGL + N G+
Sbjct: 21 PEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMG 80
Query: 79 SFLLLTVALLASYSVHLLLSMC------IQTAVTSYEDLGLFAFGLP-----------GK 121
LL + ++A + + +L+ + + Y D ++ G+
Sbjct: 81 PISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGR 140
Query: 122 LVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGI-VF 180
VV +I+ +G Y + + I E G + + +T+++ + ++
Sbjct: 141 RVVDFFLIVTQLGFCCVYFVFLADNFKQVI-EAANGTTNNCH--NNETVILTPTMDSRLY 197
Query: 181 PLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKP 240
L+ LP + L + +L + F+L+ I ++ L + Y F + + D
Sbjct: 198 MLSFLPFLVLLVFIRNLRA--LSIFSLLANI---TMLVSLVMIYQ---FIVQRIPDPSHL 249
Query: 241 KLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISA 300
L K T FSF +LP+ +++ P K + + + + ++Y
Sbjct: 250 PLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPL--ILYLGMVIVTILYISLG 307
Query: 301 LFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFF 360
GYL F ++ + L + + +VKL + T L + + + F
Sbjct: 308 CLGYLQFGANIQGSITLN----LPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFV 363
Query: 361 SNFP--FSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKL 418
S P + + L + +LAI +P + V +VG+ +S+ L I P L +
Sbjct: 364 SRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTT 423
Query: 419 SREDFLS----WKKLGAFVLLIFGILVGNF 444
+ +S +K +L G +VG +
Sbjct: 424 FYSEGMSPLTIFKDALISILGFVGFVVGTY 453
>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
sapiens]
Length = 511
Score = 39.3 bits (90), Expect = 0.007
Identities = 40/190 (21%), Positives = 84/190 (44%), Gaps = 11/190 (5%)
Query: 255 TMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESE 314
T F+F +LP+ +++ P ++ V +++ ++Y + GY+ F ++
Sbjct: 300 TAIFTFEGVGMVLPLKNQMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQAS 357
Query: 315 LLKGYSKYLSHDVVVMTVKLCILFAVLLTVPL-IHFPARKAVTMMFFSNFPFSWIRHFLI 373
+ L + + +VKL + T L H PA + + S SW +
Sbjct: 358 ITLN----LPNCWLYQSVKLMYSIGIFFTYALQFHVPA-EIIIPFAISQVSESWALFVDL 412
Query: 374 TL--ALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGA 431
++ AL + + AI +P + V +VG+ +S+ L I P L + + + +S +
Sbjct: 413 SVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAK 472
Query: 432 FVLL-IFGIL 440
+++ I G+L
Sbjct: 473 DIMISIVGLL 482
Score = 38.1 bits (87), Expect = 0.017
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 17 SVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVMANTGVF 76
S+ ++ +E S + S +H G+S ++ +L+ +G+G+LGL + N G+
Sbjct: 14 SLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLL 73
Query: 77 GFSFLLLTVALLASYSVHLLLSMCIQ 102
LL + +L + + +LL+ C Q
Sbjct: 74 VGPVSLLAIGVLTVHCMVILLN-CAQ 98
>gi|7657373 tetraspan NET-6 [Homo sapiens]
Length = 204
Score = 32.7 bits (73), Expect = 0.70
Identities = 22/59 (37%), Positives = 37/59 (62%), Gaps = 3/59 (5%)
Query: 172 IIICVGI-VFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCP-LTLNYVEKG 228
++I VGI +F +AL+ IG + + L FF+M+ L+V I ++S+ C L LN ++G
Sbjct: 48 VVIAVGIFLFLIALVGLIGAVKHHQVLLFFYMII-LLLVFIVQFSVSCACLALNQEQQG 105
>gi|225637489 hypothetical protein LOC54777 [Homo sapiens]
Length = 2441
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query: 93 VHLLLSMCIQTAVTSYEDLGLFAFGL-----PGKLVVAGTIIIQN--IGAMSSYLLIIKT 145
VH+LL++ + YED L A+ L+ AG +++N + A SS+LL+ K
Sbjct: 1030 VHILLALVLSPGAEGYEDCCLAAYAFFRHIWQVSLMTAGKSVLENRPLAATSSHLLLPKK 1089
Query: 146 E 146
E
Sbjct: 1090 E 1090
>gi|52693931 olfactory receptor, family 4, subfamily F, member 6
[Homo sapiens]
Length = 312
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 292 SFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIH 348
SFLI IS +F +T K + K +S +H +VV+ V ++F + P H
Sbjct: 210 SFLILIISYIFILVTVQKKSSGGIFKAFSMLSAHVIVVVLVFGPLIFFYIFPFPTSH 266
>gi|4557311 adenosine monophosphate deaminase 1 (isoform M) [Homo
sapiens]
Length = 747
Score = 30.4 bits (67), Expect = 3.5
Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 5/40 (12%)
Query: 222 LNYVEKGFQISNVTDDCKPKLFHFSKE---SAYALPTMAF 258
L++++KG IS TDD P FHF+KE YA+ F
Sbjct: 635 LDFLQKGLMISLSTDD--PMQFHFTKEPLMEEYAIAAQVF 672
>gi|52353280 olfactory receptor, family 6, subfamily Y, member 1
[Homo sapiens]
Length = 325
Score = 29.6 bits (65), Expect = 5.9
Identities = 15/38 (39%), Positives = 24/38 (63%), Gaps = 4/38 (10%)
Query: 346 LIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVL 383
L+ FP R A ++FFS F + +L+TL N++I+L
Sbjct: 19 LLGFPTRPAFQLLFFSIF----LATYLLTLLENLLIIL 52
>gi|153252029 C-type lectin domain family 1, member B isoform a
[Homo sapiens]
Length = 229
Score = 29.3 bits (64), Expect = 7.7
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 3/45 (6%)
Query: 141 LIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVFPLALL 185
L IKT PA I+ G S W+ +L+I+CVG+V L L
Sbjct: 10 LNIKTRKPALIS---VGSASSSWWRVMALILLILCVGMVVGLVAL 51
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.143 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,077,917
Number of Sequences: 37866
Number of extensions: 602426
Number of successful extensions: 1800
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1728
Number of HSP's gapped (non-prelim): 34
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.