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Search of human proteins with 24308547
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308547 hypothetical protein LOC196500 [Homo sapiens]
(282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308547 hypothetical protein LOC196500 [Homo sapiens] 597 e-171
gi|109715839 adherens junction associated protein 1 [Homo sapiens] 46 4e-05
gi|9055278 adherens junction associated protein 1 [Homo sapiens] 46 4e-05
gi|157168329 formin 1 [Homo sapiens] 45 5e-05
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 45 7e-05
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 45 9e-05
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re... 45 9e-05
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 44 1e-04
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 44 1e-04
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 44 1e-04
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 44 1e-04
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 44 2e-04
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 44 2e-04
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 44 2e-04
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 44 2e-04
gi|19924099 synapsin I isoform Ia [Homo sapiens] 43 3e-04
gi|19924097 synapsin I isoform Ib [Homo sapiens] 43 3e-04
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 42 5e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 42 5e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 42 5e-04
gi|169166423 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 42 6e-04
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 42 6e-04
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 42 6e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 42 6e-04
gi|153792074 proline rich 12 [Homo sapiens] 42 6e-04
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 42 8e-04
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 42 8e-04
gi|47132519 Ras association and pleckstrin homology domains 1 is... 41 0.001
gi|150170670 piccolo isoform 2 [Homo sapiens] 41 0.001
>gi|24308547 hypothetical protein LOC196500 [Homo sapiens]
Length = 282
Score = 597 bits (1540), Expect = e-171
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MESRMWPALLLSHLLPLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCV 60
MESRMWPALLLSHLLPLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCV
Sbjct: 1 MESRMWPALLLSHLLPLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCV 60
Query: 61 WERAPPPSRSPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDP 120
WERAPPPSRSPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDP
Sbjct: 61 WERAPPPSRSPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDP 120
Query: 121 NSANPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQL 180
NSANPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQL
Sbjct: 121 NSANPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQL 180
Query: 181 YVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLG 240
YVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLG
Sbjct: 181 YVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLG 240
Query: 241 AFGDSPTPTPDHEEPRGGPRPGMPHPKGAPAFQLNRIPLVNL 282
AFGDSPTPTPDHEEPRGGPRPGMPHPKGAPAFQLNRIPLVNL
Sbjct: 241 AFGDSPTPTPDHEEPRGGPRPGMPHPKGAPAFQLNRIPLVNL 282
>gi|109715839 adherens junction associated protein 1 [Homo sapiens]
Length = 411
Score = 45.8 bits (107), Expect = 4e-05
Identities = 70/248 (28%), Positives = 98/248 (39%), Gaps = 46/248 (18%)
Query: 17 LWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPS-------APRHVCVWERAPPPSR 69
L P L PP A SS S + + + A G P RH+ + SR
Sbjct: 111 LVPKAGLAKPPAAAKSSPSLASSSSSSSSAVAGGAPEQQALLRRGKRHLQGDGLSSFDSR 170
Query: 70 SPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSR----------EDGGD 119
R + G P+G EE S+ +P V+GPT
Sbjct: 171 GSRPTTETEFIAWG------PTGDEEALESNTFPG--VYGPTTVSILQTRKTTVAATTTT 222
Query: 120 PNSANP------GF---LDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFG 170
+A P GF LD P G++T P S S +G+ + + P L
Sbjct: 223 TTTATPMTLQTKGFTESLDPRRRIPGGVSTTEP-STSPSNNGE---VTQPPRIL------ 272
Query: 171 GRGEGVDPQLYVTITISIIIVLVA--TGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPL 228
G G+ +TIT+S+I+V+ A T ++ K C +S RR S Q+ +QEES Q L
Sbjct: 273 GEASGLAVHQIITITVSLIMVIAALITTLVLKNCCAQSGNTRRNSHQRKTNQQEESCQNL 332
Query: 229 TDLSPAGV 236
TD A V
Sbjct: 333 TDFPSARV 340
Score = 29.6 bits (65), Expect = 3.1
Identities = 42/168 (25%), Positives = 60/168 (35%), Gaps = 26/168 (15%)
Query: 36 PRTPPAPARPPCARGGPSAPRHVCVWERAPPPSR----SPRVPRSRRQVLP-GTAPPATP 90
PR+PP P R R G A VW PP ++PR+RR P A P
Sbjct: 54 PRSPPRPPRLWSFRSGQPARVPAPVWSPRPPRVERIHGQMQMPRARRAHRPRDQAAALVP 113
Query: 91 SGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPHPNSDSMRG 150
PP+ A P+++ ++ G AP A ++G
Sbjct: 114 KAGLAKPPA-----AAKSSPSLASSSSSSSSAVAGG-------APEQQALLRRGKRHLQG 161
Query: 151 DGDGLI--LGEAPATLRPFL-FGGRGE------GVDPQLYVTITISII 189
DG G P T F+ +G G+ P +Y T+SI+
Sbjct: 162 DGLSSFDSRGSRPTTETEFIAWGPTGDEEALESNTFPGVYGPTTVSIL 209
>gi|9055278 adherens junction associated protein 1 [Homo sapiens]
Length = 411
Score = 45.8 bits (107), Expect = 4e-05
Identities = 70/248 (28%), Positives = 98/248 (39%), Gaps = 46/248 (18%)
Query: 17 LWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPS-------APRHVCVWERAPPPSR 69
L P L PP A SS S + + + A G P RH+ + SR
Sbjct: 111 LVPKAGLAKPPAAAKSSPSLASSSSSSSSAVAGGAPEQQALLRRGKRHLQGDGLSSFDSR 170
Query: 70 SPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSR----------EDGGD 119
R + G P+G EE S+ +P V+GPT
Sbjct: 171 GSRPTTETEFIAWG------PTGDEEALESNTFPG--VYGPTTVSILQTRKTTVAATTTT 222
Query: 120 PNSANP------GF---LDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFG 170
+A P GF LD P G++T P S S +G+ + + P L
Sbjct: 223 TTTATPMTLQTKGFTESLDPRRRIPGGVSTTEP-STSPSNNGE---VTQPPRIL------ 272
Query: 171 GRGEGVDPQLYVTITISIIIVLVA--TGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPL 228
G G+ +TIT+S+I+V+ A T ++ K C +S RR S Q+ +QEES Q L
Sbjct: 273 GEASGLAVHQIITITVSLIMVIAALITTLVLKNCCAQSGNTRRNSHQRKTNQQEESCQNL 332
Query: 229 TDLSPAGV 236
TD A V
Sbjct: 333 TDFPSARV 340
Score = 29.6 bits (65), Expect = 3.1
Identities = 42/168 (25%), Positives = 60/168 (35%), Gaps = 26/168 (15%)
Query: 36 PRTPPAPARPPCARGGPSAPRHVCVWERAPPPSR----SPRVPRSRRQVLP-GTAPPATP 90
PR+PP P R R G A VW PP ++PR+RR P A P
Sbjct: 54 PRSPPRPPRLWSFRSGQPARVPAPVWSPRPPRVERIHGQMQMPRARRAHRPRDQAAALVP 113
Query: 91 SGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPHPNSDSMRG 150
PP+ A P+++ ++ G AP A ++G
Sbjct: 114 KAGLAKPPA-----AAKSSPSLASSSSSSSSAVAGG-------APEQQALLRRGKRHLQG 161
Query: 151 DGDGLI--LGEAPATLRPFL-FGGRGE------GVDPQLYVTITISII 189
DG G P T F+ +G G+ P +Y T+SI+
Sbjct: 162 DGLSSFDSRGSRPTTETEFIAWGPTGDEEALESNTFPGVYGPTTVSIL 209
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 45.4 bits (106), Expect = 5e-05
Identities = 27/76 (35%), Positives = 31/76 (40%), Gaps = 13/76 (17%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPG 83
P+PP + G P PP P PP + GP PPP P +P S PG
Sbjct: 670 PMPPVSAGPPLPPPPPPPPPLPPPSSAGP------------PPPPPPPPLPNSPAPPNPG 717
Query: 84 TAPPA-TPSGFEEGPP 98
PPA P G PP
Sbjct: 718 GPPPAPPPPGLAPPPP 733
Score = 37.7 bits (86), Expect = 0.011
Identities = 30/86 (34%), Positives = 32/86 (37%), Gaps = 16/86 (18%)
Query: 19 PLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRR 78
P L P PPP S PP P PP P+ P PPP+ P
Sbjct: 678 PPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPN-----PGGPPPAPPP------- 725
Query: 79 QVLPGTAPPATPS-GFEEGPPSSQYP 103
PG APP P F G SSQ P
Sbjct: 726 ---PGLAPPPPPGLFFGLGSSSSQCP 748
Score = 32.7 bits (73), Expect = 0.37
Identities = 27/101 (26%), Positives = 31/101 (30%), Gaps = 6/101 (5%)
Query: 26 PPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTA 85
P S+ PP PA P PS + PP S P +P P
Sbjct: 633 PMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP------PPPP 686
Query: 86 PPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPG 126
PP P GPP P + P G P PG
Sbjct: 687 PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPG 727
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 45.1 bits (105), Expect = 7e-05
Identities = 29/81 (35%), Positives = 35/81 (43%), Gaps = 4/81 (4%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRS-PRVPRSRRQVLP 82
P PPPA+G + P P P+R P A P P V PPP+R P P + P
Sbjct: 299 PPPPPARGRGAPP---PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAP 355
Query: 83 GTAPPATPSGFEEGPPSSQYP 103
PP PS GP + P
Sbjct: 356 SGPPPPPPSVLGVGPVAPPPP 376
Score = 44.3 bits (103), Expect = 1e-04
Identities = 32/82 (39%), Positives = 35/82 (42%), Gaps = 7/82 (8%)
Query: 24 PLPPPAQGSSSSPRTPP---APARPPC-ARGGPSAP--RHVCVWERAPPPSR-SPRVPRS 76
P PPP++G P PP P PP RG P P R PPPSR S VP
Sbjct: 278 PPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP 337
Query: 77 RRQVLPGTAPPATPSGFEEGPP 98
+ PPA PS GPP
Sbjct: 338 PPNRMYPPPPPALPSSAPSGPP 359
Score = 42.4 bits (98), Expect = 5e-04
Identities = 38/124 (30%), Positives = 43/124 (34%), Gaps = 25/124 (20%)
Query: 26 PPPAQGSSSSPRTPPAPAR-----PPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQV 80
PPP S P PP P PP ARG + P PPPSR+P
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPP---------PPPSRAP-------TA 320
Query: 81 LPGTAPPATPS-GFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLA 139
P PP+ PS PP+ YP P + P P L G AP
Sbjct: 321 APPPPPPSRPSVAVPPPPPNRMYPPP---PPALPSSAPSGPPPPPPSVLGVGPVAPPPPP 377
Query: 140 TPHP 143
P P
Sbjct: 378 PPPP 381
Score = 34.7 bits (78), Expect = 0.097
Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 19 PLLLLPLPPPAQGSSSSP-------RTPPAPARPPCARGG--PSAPRHVCVWERAPPPSR 69
P P PPP++ S + P PP PA P A G P P + V APPP
Sbjct: 318 PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP 377
Query: 70 SPRVPRSRRQVLPG-TAPPATPSGFEEGPPSS 100
P P PG PP PS + P++
Sbjct: 378 PPPPP-------PGPPPPPGLPSDGDHQVPTT 402
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 44.7 bits (104), Expect = 9e-05
Identities = 73/303 (24%), Positives = 96/303 (31%), Gaps = 68/303 (22%)
Query: 19 PLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRR 78
PLL P PP S + P P A P GG P + PPP + P +P S
Sbjct: 853 PLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSL-----PPPPLQPPSLPLSMG 907
Query: 79 QVLPG------------TAPPATPSGFEEGPPS------SQYPWAIVWGPTVSREDGGDP 120
VLP P +PSG+ PP S P A PT S P
Sbjct: 908 PVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPP 967
Query: 121 NSANP-------GFLDYGFAAPH-----------------GLATPHPNSDSMRGDGDGLI 156
+P G L +G H G A P P +S RG G
Sbjct: 968 APVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMES-RGTPAGPP 1026
Query: 157 LGEAPATLRPFL-FGGRGEGVDPQLYVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQ 215
P ++ P L G G G + + + P +
Sbjct: 1027 ENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPV-----------------PASPHPKHK 1069
Query: 216 QGALRQEESQQPLTDLSPAGVTVLGAFGDSPTPTPDHEEPRGGPRPGMPHPKGAPAFQLN 275
AL Q + L +S GVTV + P PR +P +P K P + +
Sbjct: 1070 VSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPR--EKPPLPATKAVPTPRQS 1127
Query: 276 RIP 278
+P
Sbjct: 1128 TVP 1130
Score = 31.6 bits (70), Expect = 0.82
Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 18 WPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAP-PPSRSPRVPRS 76
WP L P P PPAPA+ + P P +C+ P P S SP P S
Sbjct: 779 WPSL--PETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVS 836
Query: 77 R 77
+
Sbjct: 837 K 837
>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform b [Homo sapiens]
Length = 1130
Score = 44.7 bits (104), Expect = 9e-05
Identities = 41/139 (29%), Positives = 47/139 (33%), Gaps = 27/139 (19%)
Query: 26 PPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVC---VWERAPPPSRSPRV--------- 73
PPPA S P P A PP G AP V APP S P
Sbjct: 992 PPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1051
Query: 74 -PRSRRQV---LPGTAPPATPSGFEEGP---PSSQYPWAIVWGPTVSREDGGDPNSANPG 126
P+ ++ PG PP P GP P+ Q P S G P S +PG
Sbjct: 1052 GPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTP--------PSMMPGAVPGSGHPG 1103
Query: 127 FLDYGFAAPHGLATPHPNS 145
D G P P P +
Sbjct: 1104 VADPGTPLPPDPTAPSPGT 1122
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 44.3 bits (103), Expect = 1e-04
Identities = 75/268 (27%), Positives = 92/268 (34%), Gaps = 75/268 (27%)
Query: 23 LPLPP---PAQGS-----SSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPS--RSPR 72
LPLPP P+Q S S + PA P G PS P+ ER P R P+
Sbjct: 606 LPLPPARSPSQESIGARSRGSGHSQEQPAPQPSG-GDPSPPQ-----ERNLPEGTERPPK 659
Query: 73 VPRSRRQVLPGTAPPATPSGFEEGPPSSQ-------YPWAIVW--GPTVSREDGGDPNSA 123
+ S LPG PP + +G PSS PWA + GP + D P
Sbjct: 660 LCSS----LPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRR 715
Query: 124 NPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLI---LGE-APATLRPFLFGGRGEGVDPQ 179
+ H L+ P P G+ +G + LG A T RP GR V
Sbjct: 716 S-----------HSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRP----GRSALVRTS 760
Query: 180 LYVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVL 239
VT T R P Q ALR P P +
Sbjct: 761 PSVTPT---------------------PARGTPRSQSFALRARRKGPP----PPPPKRLS 795
Query: 240 GAFGDSPTPTPDHEEPRGGPRPGMPHPK 267
G SP P P E P GP+ G P+
Sbjct: 796 SVSGPSPEPPPLDESP--GPKEGATGPR 821
Score = 29.6 bits (65), Expect = 3.1
Identities = 29/99 (29%), Positives = 39/99 (39%), Gaps = 4/99 (4%)
Query: 8 ALLLSHLLPLWPLLLLPLPPPAQGSS--SSPRTPPAPARPPCARGGPSAPRHVCVWERAP 65
ALL + P PLP P G S +S P P+ P A+G P+ +
Sbjct: 923 ALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLP-AQGVPTPLAPSPAMQPPV 981
Query: 66 PPSRSPRVPRSRRQVLPG-TAPPATPSGFEEGPPSSQYP 103
PP P + S G T PPA P+ + P + P
Sbjct: 982 PPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAP 1020
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 44.3 bits (103), Expect = 1e-04
Identities = 75/268 (27%), Positives = 92/268 (34%), Gaps = 75/268 (27%)
Query: 23 LPLPP---PAQGS-----SSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPS--RSPR 72
LPLPP P+Q S S + PA P G PS P+ ER P R P+
Sbjct: 688 LPLPPARSPSQESIGARSRGSGHSQEQPAPQPSG-GDPSPPQ-----ERNLPEGTERPPK 741
Query: 73 VPRSRRQVLPGTAPPATPSGFEEGPPSSQ-------YPWAIVW--GPTVSREDGGDPNSA 123
+ S LPG PP + +G PSS PWA + GP + D P
Sbjct: 742 LCSS----LPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRR 797
Query: 124 NPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLI---LGE-APATLRPFLFGGRGEGVDPQ 179
+ H L+ P P G+ +G + LG A T RP GR V
Sbjct: 798 S-----------HSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRP----GRSALVRTS 842
Query: 180 LYVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVL 239
VT T R P Q ALR P P +
Sbjct: 843 PSVTPT---------------------PARGTPRSQSFALRARRKGPP----PPPPKRLS 877
Query: 240 GAFGDSPTPTPDHEEPRGGPRPGMPHPK 267
G SP P P E P GP+ G P+
Sbjct: 878 SVSGPSPEPPPLDESP--GPKEGATGPR 903
Score = 29.6 bits (65), Expect = 3.1
Identities = 29/99 (29%), Positives = 39/99 (39%), Gaps = 4/99 (4%)
Query: 8 ALLLSHLLPLWPLLLLPLPPPAQGSS--SSPRTPPAPARPPCARGGPSAPRHVCVWERAP 65
ALL + P PLP P G S +S P P+ P A+G P+ +
Sbjct: 1005 ALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLP-AQGVPTPLAPSPAMQPPV 1063
Query: 66 PPSRSPRVPRSRRQVLPG-TAPPATPSGFEEGPPSSQYP 103
PP P + S G T PPA P+ + P + P
Sbjct: 1064 PPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAP 1102
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 44.3 bits (103), Expect = 1e-04
Identities = 42/148 (28%), Positives = 54/148 (36%), Gaps = 18/148 (12%)
Query: 23 LPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLP 82
+P PPP Q P P P +PP + P H ++ PPP + P + P
Sbjct: 60 IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPH--QQQQPPPPPQDSSKPVVAQGPGP 117
Query: 83 ----GTAPPATPSGFEEGPPSSQYPWAIVWGPT------VSREDGGDPNSANPGF----- 127
G+APPA+ S PP+S P GPT V+ G P P
Sbjct: 118 APGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTT 177
Query: 128 -LDYGFAAPHGLATPHPNSDSMRGDGDG 154
G P A P P +G G G
Sbjct: 178 PPQAGGPPPPPAAVPGPGPGPKQGPGPG 205
Score = 28.9 bits (63), Expect = 5.3
Identities = 55/244 (22%), Positives = 71/244 (29%), Gaps = 67/244 (27%)
Query: 27 PPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAP 86
P G S PP P PP + P+ + PPP + P P+ +Q P P
Sbjct: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPP--PQQPPPHQPPPHPQPHQQQQP---P 100
Query: 87 PATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPHPNSD 146
P PP + GP + G P +++ +AP ATP P S
Sbjct: 101 P---------PPQDSSKPVVAQGPGPAPGVGSAPPASS--------SAPP--ATP-PTSG 140
Query: 147 SMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFCWDRS 206
+ G G G P P G P
Sbjct: 141 APPGSGPG------PTPTPPPAVTSAPPGAPP---------------------------- 166
Query: 207 QKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPTPTPDHEEPRGGPRPGMPHP 266
P+ + Q PA V G P P P+GG PG P P
Sbjct: 167 -----PTPPSSGVPTTPPQAGGPPPPPAAVP---GPGPGPKQGPGPGGPKGGKMPGGPKP 218
Query: 267 KGAP 270
G P
Sbjct: 219 GGGP 222
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/147 (26%), Positives = 55/147 (37%), Gaps = 12/147 (8%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPCARG-----GPSAPRHVCVWERAPPPSRSPRVPRSRR 78
P PP SS P+ P PP +G GP P+ + + PP ++ + P R
Sbjct: 689 PQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQG-HLGPQGPPGTQGMQGPPGPR 747
Query: 79 QVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGL 138
G P P G + GP S + GP + G PG + AP G+
Sbjct: 748 ----GMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRG--MQGPPGPRENQGPAPQGM 801
Query: 139 ATPHPNSDSMRGDGDGLILGEAPATLR 165
HP + G +LG P +R
Sbjct: 802 IMGHPPQEMRGPHPPGGLLGHGPQEMR 828
Score = 30.0 bits (66), Expect = 2.4
Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 6/76 (7%)
Query: 27 PPAQGSSSSPRTPPAPARPPCARG--GPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGT 84
PP GS S P PP G GP P+ R P PS+ P + ++ L G
Sbjct: 855 PP--GSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGD 912
Query: 85 AP--PATPSGFEEGPP 98
P P G GPP
Sbjct: 913 GPRAPFNQEGQSTGPP 928
>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
sapiens]
Length = 735
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/137 (29%), Positives = 53/137 (38%), Gaps = 17/137 (12%)
Query: 28 PAQGSSSSPRTPP--APARPPCARGGPSAPRHVCVWERAPPPSRSPRV----PRSRRQVL 81
PAQ SP P AP GPS+P E + P+R + P SRR VL
Sbjct: 32 PAQRPEPSPPEPEPQAPEGSQAGAEGPSSP------EASRSPARGAYLQSLEPSSRRWVL 85
Query: 82 PGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSRED----GGDPNSANPGFLDYGFAAPHG 137
G A PA + G P + P +W + ED +P PG + AP G
Sbjct: 86 -GGAKPAEDTSLGPGVPGTGEPAGEIWYNPIPEEDPRPPAPEPPGPQPGSAESEGLAPQG 144
Query: 138 LATPHPNSDSMRGDGDG 154
A P + + R G
Sbjct: 145 AAPASPPTKASRTKSPG 161
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 43.5 bits (101), Expect = 2e-04
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 16/81 (19%)
Query: 26 PPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSR------SPRVPRSRRQ 79
PPPA G S++P PP P PP P P VC+ + PPS SP P S
Sbjct: 589 PPPAPGDSTTPPPPPPPPPPP-----PPLPGGVCI---SSPPSLPGGTAISPPPPLSGDA 640
Query: 80 VLPGTAPPATPSGFEEGPPSS 100
+P PP P G PSS
Sbjct: 641 TIP--PPPPLPEGVGIPSPSS 659
Score = 33.5 bits (75), Expect = 0.22
Identities = 35/123 (28%), Positives = 44/123 (35%), Gaps = 26/123 (21%)
Query: 23 LPLPPPAQGSSSSPRTPPAPA------RPPCARGGPSAPRHVCVWERAPPPSRSPRVPRS 76
+ +PP + P PP P PP A G + P PPP P P
Sbjct: 561 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTP---------PPPPPPPPPP-- 609
Query: 77 RRQVLPG----TAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGF 132
LPG ++PP+ P G PP A + P E G P +P L G
Sbjct: 610 --PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP---SPSSLPGGT 664
Query: 133 AAP 135
A P
Sbjct: 665 AIP 667
Score = 33.5 bits (75), Expect = 0.22
Identities = 26/82 (31%), Positives = 27/82 (32%), Gaps = 25/82 (30%)
Query: 24 PLPPPAQGSSSSPRTPPA-------PARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRS 76
P PPP GS+ P PP P PP GGP P PP P
Sbjct: 680 PPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP----------PPPPFPGG--- 726
Query: 77 RRQVLPGTAPPATPSGFEEGPP 98
PG PP G PP
Sbjct: 727 -----PGIPPPPPGMGMPPPPP 743
Score = 32.3 bits (72), Expect = 0.48
Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 10/76 (13%)
Query: 23 LPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLP 82
+P PPP GS+ R PP P P + G P P + PPP P +P P
Sbjct: 666 IPPPPPLPGSA---RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP--PPPLPGG-----P 715
Query: 83 GTAPPATPSGFEEGPP 98
G PP G PP
Sbjct: 716 GIPPPPPFPGGPGIPP 731
Score = 30.0 bits (66), Expect = 2.4
Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 3/36 (8%)
Query: 23 LPLPPPAQGSSSSPRTPPA---PARPPCARGGPSAP 55
+P PPP G P PP P PP G P+AP
Sbjct: 717 IPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAP 752
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 43.5 bits (101), Expect = 2e-04
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 16/81 (19%)
Query: 26 PPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSR------SPRVPRSRRQ 79
PPPA G S++P PP P PP P P VC+ + PPS SP P S
Sbjct: 598 PPPAPGDSTTPPPPPPPPPPP-----PPLPGGVCI---SSPPSLPGGTAISPPPPLSGDA 649
Query: 80 VLPGTAPPATPSGFEEGPPSS 100
+P PP P G PSS
Sbjct: 650 TIP--PPPPLPEGVGIPSPSS 668
Score = 33.5 bits (75), Expect = 0.22
Identities = 35/123 (28%), Positives = 44/123 (35%), Gaps = 26/123 (21%)
Query: 23 LPLPPPAQGSSSSPRTPPAPA------RPPCARGGPSAPRHVCVWERAPPPSRSPRVPRS 76
+ +PP + P PP P PP A G + P PPP P P
Sbjct: 570 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTP---------PPPPPPPPPP-- 618
Query: 77 RRQVLPG----TAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGF 132
LPG ++PP+ P G PP A + P E G P +P L G
Sbjct: 619 --PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP---SPSSLPGGT 673
Query: 133 AAP 135
A P
Sbjct: 674 AIP 676
Score = 33.5 bits (75), Expect = 0.22
Identities = 26/82 (31%), Positives = 27/82 (32%), Gaps = 25/82 (30%)
Query: 24 PLPPPAQGSSSSPRTPPA-------PARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRS 76
P PPP GS+ P PP P PP GGP P PP P
Sbjct: 689 PPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP----------PPPPFPGG--- 735
Query: 77 RRQVLPGTAPPATPSGFEEGPP 98
PG PP G PP
Sbjct: 736 -----PGIPPPPPGMGMPPPPP 752
Score = 32.3 bits (72), Expect = 0.48
Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 10/76 (13%)
Query: 23 LPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLP 82
+P PPP GS+ R PP P P + G P P + PPP P +P P
Sbjct: 675 IPPPPPLPGSA---RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP--PPPLPGG-----P 724
Query: 83 GTAPPATPSGFEEGPP 98
G PP G PP
Sbjct: 725 GIPPPPPFPGGPGIPP 740
Score = 30.0 bits (66), Expect = 2.4
Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 3/36 (8%)
Query: 23 LPLPPPAQGSSSSPRTPPA---PARPPCARGGPSAP 55
+P PPP G P PP P PP G P+AP
Sbjct: 726 IPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAP 761
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 43.5 bits (101), Expect = 2e-04
Identities = 59/248 (23%), Positives = 74/248 (29%), Gaps = 70/248 (28%)
Query: 26 PPPAQGSSSSPRTPPAPARPPCARGG--PSAPRHVCVWERAPPPSRSPRVPRSRRQVLP- 82
PPP S SPR+PP + P +GG P P PPP P+ P + P
Sbjct: 80 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP---------PPPPGKPQGPPPQGGNRPQ 130
Query: 83 GTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPH 142
G PP P G S+ P R G P P G P G P
Sbjct: 131 GPPPPGKPQGPPPQGDKSRSP----------RSPPGKPQGPPP----QGGNQPQGPPPPP 176
Query: 143 PNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFC 202
G G P G+ +G PQ
Sbjct: 177 GKPQGPPPQGGKKPQGPPPP--------GKPQGPPPQ----------------------- 205
Query: 203 WDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPTPTPDHEEPRGGPRPG 262
D+S+ + P G+ + QP P G P P+GG +P
Sbjct: 206 GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG-------------KPQGPPPQGGNKPQ 252
Query: 263 MPHPKGAP 270
P P G P
Sbjct: 253 GPPPPGKP 260
Score = 42.7 bits (99), Expect = 4e-04
Identities = 60/240 (25%), Positives = 75/240 (31%), Gaps = 64/240 (26%)
Query: 26 PPPAQGSSSSPRTPPAPARPPCARGG--PSAPRHVCVWERAPPPSRSPRVPRSRRQVLP- 82
PPP S SPR+PP + P +GG P P PPP P+ P + P
Sbjct: 141 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP---------PPPPGKPQGPPPQGGKKPQ 191
Query: 83 GTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPH 142
G PP P G PP + S+ G P P G P G P
Sbjct: 192 GPPPPGKPQG---PPPQGDKSRS-------SQSPPGKPQGPPP----QGGNQPQGPPPPP 237
Query: 143 PNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFC 202
G G P G+ +G Q
Sbjct: 238 GKPQGPPPQGGNKPQGPPPP--------GKPQGPPAQ----------------------G 267
Query: 203 WDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPTP-TPDHEEPRGGPRP 261
+SQ R P G+ Q+E P PAG G+ P P +P+G PRP
Sbjct: 268 GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG-------GNPQQPQAPPAGQPQGPPRP 320
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/87 (36%), Positives = 38/87 (43%), Gaps = 12/87 (13%)
Query: 24 PLPPPAQGSSSSPRTPPAPARP--PCARGG--PSAPRHVCVWERAPP---PSRSPRVPRS 76
P PP QG + PP P +P P +GG P P + PP SRSPR P
Sbjct: 97 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPG 156
Query: 77 RRQVLP---GTAP--PATPSGFEEGPP 98
+ Q P G P P P G +GPP
Sbjct: 157 KPQGPPPQGGNQPQGPPPPPGKPQGPP 183
Score = 37.0 bits (84), Expect = 0.019
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 16/85 (18%)
Query: 24 PLPPPAQGSSSSPRTPPAPARP--PCARGGPSAPRHVCVWERAPP--PSRSPRVPRSRRQ 79
P PP QG + P+ PP P +P P A+GG + R+PP P P+ + Q
Sbjct: 240 PQGPPPQGGNK-PQGPPPPGKPQGPPAQGGSKSQS-----ARSPPGKPQGPPQQEGNNPQ 293
Query: 80 VLPGTA------PPATPSGFEEGPP 98
P A P A P+G +GPP
Sbjct: 294 GPPPPAGGNPQQPQAPPAGQPQGPP 318
Score = 34.3 bits (77), Expect = 0.13
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 12/80 (15%)
Query: 24 PLPPPAQGSSSSPRTPPAPARP--PCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVL 81
P PP QG + PP P +P P +GG + PPP P+ P ++
Sbjct: 219 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK--------PQGPPPPGKPQGPPAQGGSK 270
Query: 82 PGTAPPATPSGFEEGPPSSQ 101
+A +P G +GPP +
Sbjct: 271 SQSA--RSPPGKPQGPPQQE 288
Score = 31.6 bits (70), Expect = 0.82
Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 6/35 (17%)
Query: 26 PPPAQGSSSSPRTPPA-----PARPPCARGGPSAP 55
PPPA G+ P+ PPA P RPP G PS P
Sbjct: 296 PPPAGGNPQQPQAPPAGQPQGPPRPP-QGGRPSRP 329
Score = 31.2 bits (69), Expect = 1.1
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 20/84 (23%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPP----SRSPRVPRSRRQ 79
P PPP + P+ P PP P P + PPP SRS + P + Q
Sbjct: 172 PPPPPGKPQGPPPQGGKKPQGPP----PPGKP-------QGPPPQGDKSRSSQSPPGKPQ 220
Query: 80 VLP---GTAP--PATPSGFEEGPP 98
P G P P P G +GPP
Sbjct: 221 GPPPQGGNQPQGPPPPPGKPQGPP 244
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/128 (32%), Positives = 50/128 (39%), Gaps = 19/128 (14%)
Query: 13 HLLPLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPR 72
HL L P PLP +S+P+ P + A PP +G R V APP +R P
Sbjct: 492 HLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPP-TQGQGRQSRPVAGGPGAPPAARPPA 550
Query: 73 VPRSRRQVLP----------GTAPP----ATPSGFE-EGPPSSQYPWAIVWGPTVSREDG 117
P +RQ P G APP A P G + +GPP A GPT
Sbjct: 551 SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPA---GPTRQASQA 607
Query: 118 GDPNSANP 125
G P
Sbjct: 608 GPVPRTGP 615
Score = 38.9 bits (89), Expect = 0.005
Identities = 61/255 (23%), Positives = 79/255 (30%), Gaps = 60/255 (23%)
Query: 27 PPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAP 86
P + +S P PPA RPP +GGP P +R PP + R P +Q L G P
Sbjct: 443 PLGRQTSQQPAGPPAQQRPP-PQGGPPQPGPGP--QRQGPPLQQ-RPPPQGQQHLSGLGP 498
Query: 87 PA---TPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPHP 143
PA P + Q P + PT + P + PG A P +P
Sbjct: 499 PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPP--AARPPASPSPQR 556
Query: 144 NSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFCW 203
+ + + G AP GG+ PQ
Sbjct: 557 QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ------------------------ 592
Query: 204 DRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPTPTPDHEEPRGGPRPGM 263
+P G G RQ P+ P PT PRP
Sbjct: 593 -------KPPGPAGPTRQASQAGPVPRTGP--------------PTTQQ------PRPSG 625
Query: 264 PHPKGAPAFQLNRIP 278
P P G P QL + P
Sbjct: 626 PGPAGRPKPQLAQKP 640
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/128 (32%), Positives = 50/128 (39%), Gaps = 19/128 (14%)
Query: 13 HLLPLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPR 72
HL L P PLP +S+P+ P + A PP +G R V APP +R P
Sbjct: 492 HLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPP-TQGQGRQSRPVAGGPGAPPAARPPA 550
Query: 73 VPRSRRQVLP----------GTAPP----ATPSGFE-EGPPSSQYPWAIVWGPTVSREDG 117
P +RQ P G APP A P G + +GPP A GPT
Sbjct: 551 SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPA---GPTRQASQA 607
Query: 118 GDPNSANP 125
G P
Sbjct: 608 GPVPRTGP 615
Score = 38.9 bits (89), Expect = 0.005
Identities = 61/260 (23%), Positives = 80/260 (30%), Gaps = 52/260 (20%)
Query: 27 PPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAP 86
P + +S P PPA RPP +GGP P +R PP + R P +Q L G P
Sbjct: 443 PLGRQTSQQPAGPPAQQRPP-PQGGPPQPGPGP--QRQGPPLQQ-RPPPQGQQHLSGLGP 498
Query: 87 PA---TPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPHP 143
PA P + Q P + PT + P + PG A P +P
Sbjct: 499 PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPP--AARPPASPSPQR 556
Query: 144 NSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFCW 203
+ + + G AP GG+ PQ
Sbjct: 557 QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ------------------------ 592
Query: 204 DRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPT----------PTPDHE 253
+P G G RQ P+ P G P P+ D
Sbjct: 593 -------KPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVP 645
Query: 254 EPRGGPRPGMPHP--KGAPA 271
P G PHP K +PA
Sbjct: 646 PPATAAAGGPPHPQLKASPA 665
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 42.4 bits (98), Expect = 5e-04
Identities = 46/133 (34%), Positives = 58/133 (43%), Gaps = 28/133 (21%)
Query: 21 LLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQV 80
LL PL P G+ S P+PA PP ARGG P H + PP SRSP +
Sbjct: 925 LLTPLQP---GARSPQAAQPSPA-PPGARGGLGLPEH---FLPPPPSSRSPSSSPGQLGQ 977
Query: 81 LPG-------TAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANP-GFLDYGF 132
PG T P +TP E PP P ++V G + GG A+P GF G
Sbjct: 978 PPGELSLGLATGPLSTP----ETPPRQPEPPSLVAGAS-----GG----ASPVGFTPRGG 1024
Query: 133 AAPHGLATPHPNS 145
+P G + P +
Sbjct: 1025 LSPPGHSPGPPRT 1037
Score = 29.3 bits (64), Expect = 4.1
Identities = 46/183 (25%), Positives = 60/183 (32%), Gaps = 36/183 (19%)
Query: 19 PLLLLPLPPPAQGSSSS----------------------PRTPPAPARPP---CARGGPS 53
P LP PP ++ SSS P TPP PP G +
Sbjct: 955 PEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGA 1014
Query: 54 APRHVCVWERAPPPSRSPRVPRSRRQVLPGTAPPATPS-GFEEGPPSSQYPWAIVWGPTV 112
+P PP SP PR+ P P A+ S G PP+S P P V
Sbjct: 1015 SPVGFTPRGGLSPPGHSPGPPRT----FPSAPPRASGSHGSLLLPPASSPP-----PPQV 1065
Query: 113 SREDGGDPNSANPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGR 172
+ G P + D + A P + ++R GE+ A F G
Sbjct: 1066 PQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLR-RASPHSSGESMAAFPLFPRAGG 1124
Query: 173 GEG 175
G G
Sbjct: 1125 GSG 1127
Score = 29.3 bits (64), Expect = 4.1
Identities = 32/108 (29%), Positives = 40/108 (37%), Gaps = 19/108 (17%)
Query: 26 PPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTA 85
PP A GS S PPA + PP P P+ R PP R+ + + L +
Sbjct: 1042 PPRASGSHGSLLLPPASSPPP-----PQVPQ-----RRGTPPLTPGRLTQDLK--LISAS 1089
Query: 86 PPATPSGFEE-----GPPSSQYPWAIVWGPTVSREDGGDPNSANPGFL 128
PA P + P SS A P R GG S + G L
Sbjct: 1090 QPALPQDGAQTLRRASPHSSGESMAAF--PLFPRAGGGSGGSGSSGGL 1135
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 42.4 bits (98), Expect = 5e-04
Identities = 48/154 (31%), Positives = 62/154 (40%), Gaps = 21/154 (13%)
Query: 7 PALLLSH-LLPLWPLLLLPLPPP------AQGSSSSPRTPPA-PARPPCARGGPSAPR-- 56
P L +H LP PL L PPP A +P +PPA P P A P AP
Sbjct: 372 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 431
Query: 57 --HVCVWERAPPPSRSPRVPRSRRQVLPGTAPPATPSGF--EEGPPSSQYPWAIVWGPTV 112
H+ +PPPS + P S P +PP +PS + PPS P + P+
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFS-----PPASPPVSPSATPPSQAPPSLAAP-PLQVPPSP 485
Query: 113 SREDGGDPNSANPGFLDYGFAAPH-GLATPHPNS 145
P++ P AAP LA P P +
Sbjct: 486 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519
Score = 40.8 bits (94), Expect = 0.001
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 19 PLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRR 78
PLL +P PPA + +PR PP P P + GP + PPPSRSP S
Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPG-PDTSVSGPRLTLALAPGP-PPPPSRSPSSTLSGP 626
Query: 79 QVL----PGTAPPATPSGFEEGP 97
+ T+ P G++ GP
Sbjct: 627 DLAGHSSSATSTPEELRGYDSGP 649
Score = 38.5 bits (88), Expect = 0.007
Identities = 29/85 (34%), Positives = 36/85 (42%), Gaps = 10/85 (11%)
Query: 19 PLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRR 78
P L +P PPA S TPP A PP A + P + PPP P +
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLA----APPLQLA----KPPPQAPPALATPPL 528
Query: 79 QVLPGTAPPATPSGFEEGPPSSQYP 103
Q LP +PPA+ G PS+ P
Sbjct: 529 QALP--SPPASFPGQAPFSPSASLP 551
Score = 37.4 bits (85), Expect = 0.015
Identities = 37/122 (30%), Positives = 48/122 (39%), Gaps = 15/122 (12%)
Query: 7 PALLLSHLL------PLWPLLLLPLPPPAQGSSSSPRTPPAPARP----PCARGGPSAPR 56
P L HLL P P + P PPA S TPP+ A P P + PS P
Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 487
Query: 57 HVCVWERAPPPSRSP---RVPRSRRQVLPGTAPP--ATPSGFEEGPPSSQYPWAIVWGPT 111
+ A PP ++P P + P APP ATP P + +P + P+
Sbjct: 488 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 547
Query: 112 VS 113
S
Sbjct: 548 AS 549
Score = 36.6 bits (83), Expect = 0.025
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 12/133 (9%)
Query: 20 LLLLPLPPPAQGSSSSPRTPPA-PARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRR 78
LL P PP +P +PPA P P A AP + PPS P S
Sbjct: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 494
Query: 79 QVLPGTAPP---ATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAP 135
P APP A P + PP Q P A+ P + P ++ PG + +A
Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPP--QAPPALATPPLQALP---SPPASFPGQAPFSPSAS 549
Query: 136 ---HGLATPHPNS 145
LATP P +
Sbjct: 550 LPMSPLATPPPQA 562
Score = 36.2 bits (82), Expect = 0.033
Identities = 44/133 (33%), Positives = 54/133 (40%), Gaps = 31/133 (23%)
Query: 25 LPPPAQGSSSSPRTP-PAPARP-PCARGGPSAPRHVCVWERAPPPS-----RSPRVPRSR 77
L PA S SS TP +PAR P ARG P AP H P P R P+V R
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH----PSQPKPKGLQALRPPQVTPPR 289
Query: 78 RQVLP-----GTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGF 132
+ P ++P ATPS SQ P PT+ P + + L
Sbjct: 290 KDAAPALGPLSSSPLATPS--PSAALQSQAP------PTL-------PATPHSSSLTCQL 334
Query: 133 AAPHGLATPHPNS 145
A P LA P P++
Sbjct: 335 ATPLPLAPPSPSA 347
Score = 34.3 bits (77), Expect = 0.13
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
Query: 27 PPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAP 86
PP Q + P+ PPA A PP + PS P + P S S +P S P AP
Sbjct: 508 PPLQLAKPPPQAPPALATPPL-QALPSPPAS---FPGQAPFSPSASLPMSPLATPPPQAP 563
Query: 87 PATPSGFEEGPPS 99
P + + PPS
Sbjct: 564 PVLAAPLLQVPPS 576
Score = 32.0 bits (71), Expect = 0.63
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 14/96 (14%)
Query: 23 LPLPPPAQGSSSSPRT-PPAPARPP----CARGGPS-------APRHVCVWERAPPPSRS 70
LPL PP+ + S +T P PA PP + G P+ P PPP
Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397
Query: 71 PRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAI 106
P + Q P +PPA+P PS Q P A+
Sbjct: 398 PALALPPLQAPP--SPPASPPLSPLATPSPQAPNAL 431
Score = 31.2 bits (69), Expect = 1.1
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 10/85 (11%)
Query: 15 LPLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVP 74
LP+ PL P P ++ + PP+P P + APR P P S P
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ----APRR----PPTPGPDTSVSGP 601
Query: 75 RSRRQVLPGTAPP--ATPSGFEEGP 97
R + PG PP +PS GP
Sbjct: 602 RLTLALAPGPPPPPSRSPSSTLSGP 626
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 42.4 bits (98), Expect = 5e-04
Identities = 48/154 (31%), Positives = 62/154 (40%), Gaps = 21/154 (13%)
Query: 7 PALLLSH-LLPLWPLLLLPLPPP------AQGSSSSPRTPPA-PARPPCARGGPSAPR-- 56
P L +H LP PL L PPP A +P +PPA P P A P AP
Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392
Query: 57 --HVCVWERAPPPSRSPRVPRSRRQVLPGTAPPATPSGF--EEGPPSSQYPWAIVWGPTV 112
H+ +PPPS + P S P +PP +PS + PPS P + P+
Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFS-----PPASPPVSPSATPPSQAPPSLAAP-PLQVPPSP 446
Query: 113 SREDGGDPNSANPGFLDYGFAAPH-GLATPHPNS 145
P++ P AAP LA P P +
Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480
Score = 40.8 bits (94), Expect = 0.001
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 19 PLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRR 78
PLL +P PPA + +PR PP P P + GP + PPPSRSP S
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPG-PDTSVSGPRLTLALAPGP-PPPPSRSPSSTLSGP 587
Query: 79 QVL----PGTAPPATPSGFEEGP 97
+ T+ P G++ GP
Sbjct: 588 DLAGHSSSATSTPEELRGYDSGP 610
Score = 38.5 bits (88), Expect = 0.007
Identities = 47/141 (33%), Positives = 58/141 (41%), Gaps = 28/141 (19%)
Query: 25 LPPPAQGSSSSPRTP-PAPARP-PCARGGPSAPRHVCVWERAPPPS-----RSPRVPRSR 77
L PA S SS TP +PAR P ARG P AP H P P R P+V R
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH----PSQPKPKGLQALRPPQVTPPR 280
Query: 78 RQVLP-----GTAPPATPSGFEEGPPSSQYPWAI-------VWGPTVSREDGGDPN-SAN 124
+ P ++P ATPS PPS P ++ P+ + G P A
Sbjct: 281 KDAAPALGPLSSSPLATPS--PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338
Query: 125 PGFLDYGFAAPHGLATPHPNS 145
FL +P LATP P +
Sbjct: 339 HSFLPSPPLSP--LATPPPQA 357
Score = 38.5 bits (88), Expect = 0.007
Identities = 29/85 (34%), Positives = 36/85 (42%), Gaps = 10/85 (11%)
Query: 19 PLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRR 78
P L +P PPA S TPP A PP A + P + PPP P +
Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLA----APPLQLA----KPPPQAPPALATPPL 489
Query: 79 QVLPGTAPPATPSGFEEGPPSSQYP 103
Q LP +PPA+ G PS+ P
Sbjct: 490 QALP--SPPASFPGQAPFSPSASLP 512
Score = 37.4 bits (85), Expect = 0.015
Identities = 37/122 (30%), Positives = 48/122 (39%), Gaps = 15/122 (12%)
Query: 7 PALLLSHLL------PLWPLLLLPLPPPAQGSSSSPRTPPAPARP----PCARGGPSAPR 56
P L HLL P P + P PPA S TPP+ A P P + PS P
Sbjct: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448
Query: 57 HVCVWERAPPPSRSP---RVPRSRRQVLPGTAPP--ATPSGFEEGPPSSQYPWAIVWGPT 111
+ A PP ++P P + P APP ATP P + +P + P+
Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508
Query: 112 VS 113
S
Sbjct: 509 AS 510
Score = 36.6 bits (83), Expect = 0.025
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 12/133 (9%)
Query: 20 LLLLPLPPPAQGSSSSPRTPPA-PARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRR 78
LL P PP +P +PPA P P A AP + PPS P S
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455
Query: 79 QVLPGTAPP---ATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAP 135
P APP A P + PP Q P A+ P + P ++ PG + +A
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPP--QAPPALATPPLQALP---SPPASFPGQAPFSPSAS 510
Query: 136 ---HGLATPHPNS 145
LATP P +
Sbjct: 511 LPMSPLATPPPQA 523
Score = 34.3 bits (77), Expect = 0.13
Identities = 31/99 (31%), Positives = 37/99 (37%), Gaps = 30/99 (30%)
Query: 17 LWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRS------ 70
L PL PL P SP PP+P+ PP + PS P A PPS++
Sbjct: 287 LGPLSSSPLATP------SPSAPPSPSAPPSLQTLPSPP--------ATPPSQATTSLGS 332
Query: 71 ----------PRVPRSRRQVLPGTAPPATPSGFEEGPPS 99
P P S P APPA + PPS
Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 371
Score = 34.3 bits (77), Expect = 0.13
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
Query: 27 PPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAP 86
PP Q + P+ PPA A PP + PS P + P S S +P S P AP
Sbjct: 469 PPLQLAKPPPQAPPALATPPL-QALPSPPAS---FPGQAPFSPSASLPMSPLATPPPQAP 524
Query: 87 PATPSGFEEGPPS 99
P + + PPS
Sbjct: 525 PVLAAPLLQVPPS 537
Score = 31.2 bits (69), Expect = 1.1
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 10/85 (11%)
Query: 15 LPLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVP 74
LP+ PL P P ++ + PP+P P + APR P P S P
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ----APRR----PPTPGPDTSVSGP 562
Query: 75 RSRRQVLPGTAPP--ATPSGFEEGP 97
R + PG PP +PS GP
Sbjct: 563 RLTLALAPGPPPPPSRSPSSTLSGP 587
>gi|169166423 PREDICTED: hypothetical protein [Homo sapiens]
Length = 286
Score = 42.0 bits (97), Expect = 6e-04
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 26/109 (23%)
Query: 23 LPLPPPAQGSSSSPRTPPAPARPPCARGGPS-----APRHVCVWERAPPPSRSPRVPRSR 77
+P P AQG+ S +TP P R PCA+G PS PR C + PP ++P+VPR
Sbjct: 87 VPRVPCAQGTPSL-QTPQVP-RVPCAQGTPSLQTPQVPRVPCA--QGTPPLQTPQVPRD- 141
Query: 78 RQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPG 126
T P TP +P + G TV + G P G
Sbjct: 142 ------TVPADTPG----------FPRPVRSGDTVPADTPGSPRPVRSG 174
Score = 37.4 bits (85), Expect = 0.015
Identities = 33/88 (37%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Query: 23 LPLPPPAQGSSSSPRTPPAPARPPCARGGPS-----APRHVCVWERAPPPSRSPRVPR-S 76
+P P AQG+ S +TP P R PCA+G PS PR C + P ++P+VPR
Sbjct: 19 IPHVPCAQGTPSL-QTPQVP-RVPCAQGTPSLQTPQVPRVPCA--QGTPSLQTPQVPRVP 74
Query: 77 RRQVLPGTAPPATPS-GFEEGPPSSQYP 103
Q P P P +G PS Q P
Sbjct: 75 CAQGTPSLQTPQVPRVPCAQGTPSLQTP 102
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 42.0 bits (97), Expect = 6e-04
Identities = 30/83 (36%), Positives = 35/83 (42%), Gaps = 3/83 (3%)
Query: 19 PLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPP-SRSPRVPRSR 77
P L P PPP P PP PA+ P C +R PP + S R R
Sbjct: 425 PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREA 484
Query: 78 RQVLP-GTAPPA-TPSGFEEGPP 98
+ P GT+PP TPS GPP
Sbjct: 485 ARAGPEGTSPPTPTPSTATGGPP 507
Score = 38.9 bits (89), Expect = 0.005
Identities = 39/128 (30%), Positives = 46/128 (35%), Gaps = 26/128 (20%)
Query: 25 LPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRS-RRQVLPG 83
LPPP P TPPAP+ PP P P +PPP P P LP
Sbjct: 401 LPPP-------PLTPPAPSPPP-----PLPPPST-----SPPPPLCPPPPPPVSPPPLPS 443
Query: 84 TAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDP-NSANPGFLDYGFAAPHGLATPH 142
PP EE PP V T SR+ G P + + A P G + P
Sbjct: 444 PPPPPAQEEQEESPPP-------VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPT 496
Query: 143 PNSDSMRG 150
P + G
Sbjct: 497 PTPSTATG 504
Score = 37.7 bits (86), Expect = 0.011
Identities = 29/83 (34%), Positives = 34/83 (40%), Gaps = 15/83 (18%)
Query: 23 LPLPPPAQGSSSSPRTPPAPA----RPPCARGGPSAP--RHVCVWER--APPPSRSPRVP 74
LP PPPA +P PPAPA RP R P H+ ++E PPP +P P
Sbjct: 618 LPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAP 677
Query: 75 RSRRQVLPGTAPPATPSGFEEGP 97
PPA S E P
Sbjct: 678 EPE-------PPPADDSPAEPEP 693
Score = 37.0 bits (84), Expect = 0.019
Identities = 38/120 (31%), Positives = 44/120 (36%), Gaps = 26/120 (21%)
Query: 16 PLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPR 75
PL P P PPP S+SP P P PP P +P + PPP
Sbjct: 405 PLTPPAPSP-PPPLPPPSTSPPPPLCPPPPP-----PVSPPPL---PSPPPPPAQEEQEE 455
Query: 76 SRRQVLPGTA------PPATPSGFEE------GPPSSQYPWAIVWGPTVSREDGGDPNSA 123
S V+P T PP TPS E GP + P PT S GG P +
Sbjct: 456 SPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPP-----TPTPSTATGGPPEDS 510
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 42.0 bits (97), Expect = 6e-04
Identities = 69/274 (25%), Positives = 83/274 (30%), Gaps = 74/274 (27%)
Query: 24 PLPPPAQGSSSSPRTPPAPARP--PCARGG--PSAPRHVCVWERAPP---PSRSPRVPRS 76
P PP QG + PP P +P P +GG P P + PP SRSPR P
Sbjct: 57 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 116
Query: 77 RRQVLP---GTAP--PATPSGFEEGP-------PSSQYPWAIVWGP--------TVSRED 116
+ Q P G P P P G +GP P P GP SR
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176
Query: 117 GGDPNSANPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGV 176
G P P G P G P G G P G+ +G
Sbjct: 177 PGKPQGPPP----QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP--------GKPQGP 224
Query: 177 DPQLYVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGV 236
PQ ++SQ R P G+ + QP P G
Sbjct: 225 PPQ----------------------GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPG- 261
Query: 237 TVLGAFGDSPTPTPDHEEPRGGPRPGMPHPKGAP 270
P P+GG +P P P G P
Sbjct: 262 ------------KPQGPPPQGGNKPQGPPPPGKP 283
Score = 41.6 bits (96), Expect = 8e-04
Identities = 62/244 (25%), Positives = 78/244 (31%), Gaps = 65/244 (26%)
Query: 24 PLPPPAQGS--SSSPRTPPAPARPPCARGG--PSAPRHVCVWERAPPPSRSPRVPRSRRQ 79
P PP QG S S R+PP + P +GG P P PPP P+ P +
Sbjct: 221 PQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP---------PPPPGKPQGPPPQGG 271
Query: 80 VLP-GTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGL 138
P G PP P +GPP G + SR P G G P G
Sbjct: 272 NKPQGPPPPGKP----QGPPPQ--------GGSKSRSSRSPPGKPQ-GPPPQGGNQPQGP 318
Query: 139 ATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGII 198
P G G P G+ +G PQ
Sbjct: 319 PPPPGKPQGPPPQGGNKPQGPPPP--------GKPQGPPPQ------------------- 351
Query: 199 FKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPTP-TPDHEEPRG 257
+S+ R P G+ Q+E P PAG G+ P P +P+G
Sbjct: 352 ---GGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAG-------GNPQQPQAPPAGQPQG 401
Query: 258 GPRP 261
PRP
Sbjct: 402 PPRP 405
Score = 34.3 bits (77), Expect = 0.13
Identities = 55/248 (22%), Positives = 70/248 (28%), Gaps = 69/248 (27%)
Query: 26 PPPAQGSSSSPRTPPAPARPPCARGG--PSAPRHVCVWERAPPPSRSPRVPRSRRQVLP- 82
PP P +PP + P +GG P P PPP P+ P + P
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP---------PPPPGKPQGPPPQGGNKPQ 90
Query: 83 GTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPH 142
G PP P G S+ P R G P P G P G P
Sbjct: 91 GPPPPGKPQGPPPQGDKSRSP----------RSPPGKPQGPPP----QGGNQPQGPPPPP 136
Query: 143 PNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFC 202
G G P G+ +G PQ
Sbjct: 137 GKPQGPPPQGGNKPQGPPPP--------GKPQGPPPQ----------------------G 166
Query: 203 WDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPTPTPDHEEPRGGPRPG 262
++S+ R P G+ + QP P G P P+GG +P
Sbjct: 167 DNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG-------------KPQGPPPQGGNKPQ 213
Query: 263 MPHPKGAP 270
P P G P
Sbjct: 214 GPPPPGKP 221
Score = 31.6 bits (70), Expect = 0.82
Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 6/35 (17%)
Query: 26 PPPAQGSSSSPRTPPA-----PARPPCARGGPSAP 55
PPPA G+ P+ PPA P RPP G PS P
Sbjct: 381 PPPAGGNPQQPQAPPAGQPQGPPRPP-QGGRPSRP 414
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 42.0 bits (97), Expect = 6e-04
Identities = 43/129 (33%), Positives = 52/129 (40%), Gaps = 29/129 (22%)
Query: 7 PALLLSHLLPLWPLL-LLPLPPPAQGSSSSPRTP--PAPARPPCARGGPSAPRHVCVWER 63
PAL + HL+P P +LP+PP PR P P P RPP A P AP
Sbjct: 231 PALCV-HLVPQLPRPPVLPVPP------MPPRPPMVPMPPRPPIAPMPPMAP-------- 275
Query: 64 APPPSRSPRVPRSRRQVLPGTAPPATP-------SGFEEGPPSSQYPWAIVWGPTVSRED 116
PP SR VP R PP P + GPP + P GP ++R
Sbjct: 276 VPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVP----PGPPMARVP 331
Query: 117 GGDPNSANP 125
G P + P
Sbjct: 332 PGPPMARVP 340
Score = 38.1 bits (87), Expect = 0.009
Identities = 31/92 (33%), Positives = 37/92 (40%), Gaps = 12/92 (13%)
Query: 15 LPLWPLLLLPLPP--PAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPP-PSRSP 71
+P WP + P+PP P + P P P PP AR P P R PP P +P
Sbjct: 294 VPPWPPMA-PVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPP-----MARVPPGPPMAP 347
Query: 72 RVPRSRRQVLPGTAPPATPSGFEEGPPSSQYP 103
P LP PP P GPP + P
Sbjct: 348 LPPGPPMAPLP-PGPPMAP--LPPGPPMAPLP 376
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 42.0 bits (97), Expect = 6e-04
Identities = 65/255 (25%), Positives = 82/255 (32%), Gaps = 48/255 (18%)
Query: 28 PAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPP------PSRSPRVPRSRRQVL 81
PA S TPPA A PP +GGP+ P W PP P P P +
Sbjct: 931 PASPSPKGAPTPPA-ATPPSPKGGPATPSP--KWAPTPPAATPPSPKGGPATPSPKGAPT 987
Query: 82 PGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATP 141
P A P +P +G P++ P P V+ +A P G + P P
Sbjct: 988 PPAATPPSP----KGGPATPSPKGAPTPPAVTPPSPKGSPAATP--FPKGASTPPAATPP 1041
Query: 142 HPNSDSMRGDGDGLILGE-APATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFK 200
P +G L + AP T L +G P L T
Sbjct: 1042 SP-----KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT--------------- 1081
Query: 201 FCWDRSQKRRRPSGQQGALRQEESQQPL----TDLSPAGVTVLGAFGDSP-TPTPDHEEP 255
PS + G P+ T SP G +P TP P
Sbjct: 1082 -----PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Query: 256 RGGPRPGMPHPKGAP 270
+GG P PKGAP
Sbjct: 1137 KGG--LATPPPKGAP 1149
Score = 40.8 bits (94), Expect = 0.001
Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 22/148 (14%)
Query: 19 PLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCV---------WERAPPPSR 69
P + P PA SS +PPA P +G PS P+ + + E PP+
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPA-VTPSTYKGAPS-PKELLIPPAVTSPSPKEAPTPPAV 1619
Query: 70 SPRVPRSRRQVLPG-----TAPPATPSGFEEGPPSSQYPWAIV--WGPTVSREDGGDPNS 122
+P P + P T+PP TPS ++ P S P ++ G TV + G P
Sbjct: 1620 TPPSPE-KGPATPAPKGTPTSPPVTPSSLKDSPTS---PASVTCKMGATVPQASKGLPAK 1675
Query: 123 ANPGFLDYGFAAPHGLATPHPNSDSMRG 150
P L AP +TP + + +G
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKG 1703
Score = 38.9 bits (89), Expect = 0.005
Identities = 43/152 (28%), Positives = 55/152 (36%), Gaps = 22/152 (14%)
Query: 23 LPLPPPAQGSSSSPRTPPAPARPPCA---RGGPSAPRHVCVWERAPPPSRSPRVPRSRRQ 79
L PP + + TPP+P P +G P+ P P P SP P +
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA-----ATPPSPKGSPGTPPPKGA 1332
Query: 80 VLPGTAPPATPSGFEEGP---PSSQYPWAIVWGPTV-SREDGGDPNSANPGFLDYGFAAP 135
P P +P G P PSS+ GPT S ++G P +A P P
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSK------GGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386
Query: 136 ----HGLATPHPNSDSMRGDGDGLILGEAPAT 163
G A P P D L +APAT
Sbjct: 1387 PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418
Score = 36.6 bits (83), Expect = 0.025
Identities = 39/131 (29%), Positives = 50/131 (38%), Gaps = 15/131 (11%)
Query: 26 PPPAQGS-SSSPRTPPAPARP----PCARGGPSAP--RHVCVWERAPPPSRS--PRVPRS 76
PP +GS +++P AP P P +GGP+ P + A PPS P P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 77 RRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAP- 135
+ +P A P +P G PP P P + GG G A P
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK--GGLATPPPKGAPTTPAATPP 1157
Query: 136 ---HGLATPHP 143
GLATP P
Sbjct: 1158 SPKGGLATPPP 1168
Score = 35.4 bits (80), Expect = 0.057
Identities = 67/252 (26%), Positives = 85/252 (33%), Gaps = 47/252 (18%)
Query: 25 LPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGT 84
LP P +G ++ PAP + P S+P+ P P P P + P
Sbjct: 893 LPFPKEGPAT-----PAPKQAPALSMTSSSPKKA---RATPAPKGIPASPSPKGAPTPPA 944
Query: 85 APPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPHPN 144
A P +P G GP + WA PT P +A P G A P P P
Sbjct: 945 ATPPSPKG---GPATPSPKWA----PT--------PPAATPPSPKGGPATPSPKGAPTPP 989
Query: 145 SDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFCWD 204
+ + G PAT P +G P S AT
Sbjct: 990 AATPPSPKGG------PATPSP-----KGAPTPP---AVTPPSPKGSPAATPFPKGASTP 1035
Query: 205 RSQKRRRPSGQQGA--LRQEESQQPLTDL-SPAGVTVLGAFGDSPTP---TPDHEEPRGG 258
+ P G A L + P L SP G + +PTP TP P+GG
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP--PSPKGG 1093
Query: 259 PRPGMPHPKGAP 270
P P PKGAP
Sbjct: 1094 --PATPSPKGAP 1103
Score = 34.3 bits (77), Expect = 0.13
Identities = 39/138 (28%), Positives = 53/138 (38%), Gaps = 23/138 (16%)
Query: 24 PLPPPAQGSSSSPR-TPPAPARPPCARGGPSAPRHVCVWERAP-PPSRSPRVPRSRRQVL 81
P P +G+ + P TPP+P GGP+ P + AP PP+ +P P+
Sbjct: 977 PATPSPKGAPTPPAATPPSPK------GGPATPSP----KGAPTPPAVTPPSPKGSPAAT 1026
Query: 82 P-----GTAPPATPSGFEEGPPSSQYPWAIVWGP--TVSREDGGDPNSANPGFLDYGFAA 134
P T P ATP + P ++ P P T+ GG + G A
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Query: 135 P----HGLATPHPNSDSM 148
P G ATP P M
Sbjct: 1087 PPSPKGGPATPSPKGAPM 1104
Score = 34.3 bits (77), Expect = 0.13
Identities = 32/105 (30%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 27 PPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPG-TA 85
PPA S TP PA P ++GGP+ P E PP+ +P P
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK---EGPTPPAATPSHKGGPAMTPPSPKR 1391
Query: 86 PPATPSGFEEGPPSSQYPWAIVWGP------TVSREDGGDPNSAN 124
PA PS +G P+S P I P V+RE P+ +
Sbjct: 1392 GPAIPS--PKGDPTS--PAVIPLSPKKAPATPVTREGAATPSKGD 1432
Score = 33.9 bits (76), Expect = 0.16
Identities = 39/150 (26%), Positives = 54/150 (36%), Gaps = 29/150 (19%)
Query: 23 LPLPPPAQGSSSSPRTPPAP-----------------ARPPCARGG--PSAPRHVCVWER 63
L PPP ++ TPP+P A PP +GG +P+
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
Query: 64 APPPSRSPRVPRSRRQVLPGT--APPATPSG-----FEEGPPS--SQYPWAIVWGPTVSR 114
A PPS + + P T A P +P G +G P+ + P + GP
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259
Query: 115 EDGG-DPNSANPGFLDYGFAAPHGLATPHP 143
G P +A P L G A P P+P
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNP 1289
Score = 32.3 bits (72), Expect = 0.48
Identities = 33/142 (23%), Positives = 51/142 (35%), Gaps = 23/142 (16%)
Query: 16 PLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPS--APRHVCVWER--APPPSRSP 71
P P ++ P + SS R P AP ++ P+ AP+ + P P ++P
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP 1562
Query: 72 RVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGP------------TVSREDGGD 119
+P + PATPS E P + P P + S ++
Sbjct: 1563 AIPTPKEA-------PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615
Query: 120 PNSANPGFLDYGFAAPHGLATP 141
P + P + G A P TP
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTP 1637
Score = 30.4 bits (67), Expect = 1.8
Identities = 25/75 (33%), Positives = 31/75 (41%), Gaps = 13/75 (17%)
Query: 16 PLWPLLLLPLP--PPAQ---GSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRS 70
P P + P P PPA +SSSP+ PA P G P+ P + P
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT---PAPMGAPTLPAVI-----PSSPKEV 1516
Query: 71 PRVPRSRRQVLPGTA 85
P P SRR + TA
Sbjct: 1517 PATPSSRRDPIAPTA 1531
Score = 29.3 bits (64), Expect = 4.1
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 15/78 (19%)
Query: 17 LWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRS 76
L P + P+ ++S+P+ PA P ++G P+ P PP SP+ P +
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPAT---PSSKGDPTLP-------AVTPP--SPKEPPA 1480
Query: 77 RRQVLPGTAP---PATPS 91
+QV ++P PATP+
Sbjct: 1481 PKQVATSSSPKKAPATPA 1498
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 42.0 bits (97), Expect = 6e-04
Identities = 30/82 (36%), Positives = 35/82 (42%), Gaps = 11/82 (13%)
Query: 19 PLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRR 78
P LL PPP + +P+ P P PP PS P V AP PS P P
Sbjct: 1450 PPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLV-----APTPSSPPPPP---- 1500
Query: 79 QVLPGTAPPATPSGFEEGPPSS 100
LP PPA PS PP++
Sbjct: 1501 --LPPPPPPAMPSPPPPPPPAA 1520
Score = 38.5 bits (88), Expect = 0.007
Identities = 29/98 (29%), Positives = 35/98 (35%), Gaps = 18/98 (18%)
Query: 16 PLWPLLLLPLPPPAQG-----SSSSPRTP-----PAPARPPCARGGPSAPRHVCVWERAP 65
PL P +P PPP G S+ +P P P P PP P P P
Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP--------PP 1474
Query: 66 PPSRSPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYP 103
PP P +P V P + P P PP+ P
Sbjct: 1475 PPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512
Score = 34.3 bits (77), Expect = 0.13
Identities = 25/70 (35%), Positives = 25/70 (35%), Gaps = 4/70 (5%)
Query: 19 PLLLLPLPPP--AQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRS 76
P LP PPP A SS P P P PP P P APP P P
Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPP--EEPAAPSP 1535
Query: 77 RRQVLPGTAP 86
LP T P
Sbjct: 1536 EDPELPDTRP 1545
Score = 31.6 bits (70), Expect = 0.82
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 6/70 (8%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPC-ARGGPSAPRHVCVWERAPPPSRSPR-VPRSRRQVL 81
P PP +++ P PP P P + G P P + E PPP+ P P+ +
Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPP----LLEEKPPPTPPPAPTPQPQPPPP 1474
Query: 82 PGTAPPATPS 91
P PA PS
Sbjct: 1475 PPPPQPALPS 1484
Score = 28.9 bits (63), Expect = 5.3
Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 5/82 (6%)
Query: 25 LPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPR----VPRSRRQV 80
L P + + P PP P PP + R + AP P P P + +++
Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQEL 883
Query: 81 LPGTAP-PATPSGFEEGPPSSQ 101
L P P P GPP+S+
Sbjct: 884 LGALEPLPPAPGDTGVGPPNSE 905
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 41.6 bits (96), Expect = 8e-04
Identities = 47/164 (28%), Positives = 54/164 (32%), Gaps = 43/164 (26%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSR------ 77
P PPP P PP PA PP GP+ P+H E PP + PR R
Sbjct: 23 PPPPPPAPPQQQPPPPPPPAPPP--GPGPAPPQHPPRAEALPPEAADEGGPRGRLRSRDS 80
Query: 78 ---RQVLPGTA------------------PPATPSGFEEGPPSSQYPWAIVWGPTV---- 112
R PG A PA P G GP S GP
Sbjct: 81 SCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGP 140
Query: 113 -----SREDG--GDPNSANPGFLDYGFAAPHGLATPHPNSDSMR 149
S E G G+P + F+ F A L P N S+R
Sbjct: 141 AEEAGSEEAGPAGEPRGSQASFMQRQFGA---LLQPGVNKFSLR 181
Score = 39.3 bits (90), Expect = 0.004
Identities = 35/120 (29%), Positives = 44/120 (36%), Gaps = 22/120 (18%)
Query: 22 LLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSR---- 77
L+ PPP +++ PP PA PP A P APR P P +P R
Sbjct: 757 LVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRA 816
Query: 78 -------RQVLPGTAP-------PATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSA 123
+ LP AP PA+ S GP P A P+ R D P +A
Sbjct: 817 SRPLSASQPSLPHGAPGPAASTRPASSSTPRLGPT----PAARAAAPSPDRRDSASPGAA 872
Score = 35.4 bits (80), Expect = 0.057
Identities = 44/162 (27%), Positives = 55/162 (33%), Gaps = 24/162 (14%)
Query: 19 PLLLLPLPPP-AQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSR 77
P + PL P A GS R PP P A GP PPP+ P P S
Sbjct: 740 PQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGP------------PPPASPPGAPASP 787
Query: 78 RQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHG 137
R AP +P G G P++ + +SR P SA+ L +G P
Sbjct: 788 R------APRTSPYG---GLPAAPLAGPALPARRLSR--ASRPLSASQPSLPHGAPGPAA 836
Query: 138 LATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQ 179
P +S G R G G+DPQ
Sbjct: 837 STRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAAGGLDPQ 878
Score = 31.6 bits (70), Expect = 0.82
Identities = 39/137 (28%), Positives = 47/137 (34%), Gaps = 11/137 (8%)
Query: 48 ARGGPSAPRHV--CVWERAPPPSRSPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWA 105
ARGG P PPP P P +Q P PPA P G GP Q+P
Sbjct: 3 ARGGGGRPGESPGATPAPGPPPPPPPAPP---QQQPPPPPPPAPPPG--PGPAPPQHPPR 57
Query: 106 IVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATP---HPNSDSMRGDGDGLILG-EAP 161
P + ++GG G G A+ PN + RG+ G E P
Sbjct: 58 AEALPPEAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGP 117
Query: 162 ATLRPFLFGGRGEGVDP 178
A F RG P
Sbjct: 118 ARGPKVSFSCRGAASGP 134
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 41.6 bits (96), Expect = 8e-04
Identities = 62/244 (25%), Positives = 84/244 (34%), Gaps = 23/244 (9%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPG 83
P P QGS+ P PA PC G S P C + AP SP + + + P
Sbjct: 7033 PFCHPKQGSAPQEGCSPHPAVAPCPPG--SFPPGSC--KEAPLVPSSPFLGQPQAPPAPA 7088
Query: 84 TAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPHP 143
A P P + GP P GP S +S+ L G + P
Sbjct: 7089 KASP--PLDSKMGPGDISLPGRPKPGPCSSPGSASQASSSQVSSLRVGSSQVGTEPGPSL 7146
Query: 144 NSDSMRGDGDGLI-------LGEAPATLRPFLFGGRGEGVDPQLYVTITISIII--VLVA 194
+++ + + L + AT+R F GGRG Y T +L
Sbjct: 7147 DAEGWTQEAEDLSDSTPTLQRPQEQATMRKFSLGGRGGYAGVAGYGTFAFGGDAGGMLGQ 7206
Query: 195 TGIIFKFCWDRSQKRRRPSGQQGALRQEESQQ------PLTDLSPAGVTVLG--AFGDSP 246
+ + W SQ + A Q E QQ PL +S V +G SP
Sbjct: 7207 GPMWARIAWAVSQSEEEEQEEARAESQSEEQQEARAESPLPQVSARPVPEVGRAPTRSSP 7266
Query: 247 TPTP 250
PTP
Sbjct: 7267 EPTP 7270
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 24 PLPPPAQGSSSSPRT--PPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVL 81
P PPA+ + P + PP+P PP P+ P+ + PPPS VP +Q+
Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK-PPPSPLSPVPSVVKQIA 866
Query: 82 PGTAPPATPSGFEEGP 97
PP TP E P
Sbjct: 867 SQFPPPPTPPAMESQP 882
Score = 36.2 bits (82), Expect = 0.033
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 12/99 (12%)
Query: 7 PALLLSHLLPLWPLLLLPLPPPA--QGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERA 64
PA S++ P P +P+PPP + S + PP+P P PS + + +
Sbjct: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPV-----PSVVKQIA--SQF 869
Query: 65 PPPSRSPRVPRSRRQVLPGTAPPATPSGFEEGP---PSS 100
PPP P + + +P P +P + P PSS
Sbjct: 870 PPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSS 908
Score = 35.8 bits (81), Expect = 0.043
Identities = 28/91 (30%), Positives = 36/91 (39%), Gaps = 13/91 (14%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPG 83
P PPP GS+ + P PCA PS P+ APPP + QV P
Sbjct: 715 PPPPPTPGSAMAQLKPA-----PCA---PSLPQF-----SAPPPPLKIHQVQHITQVAPP 761
Query: 84 TAPPATPSGFEEGPPSSQYPWAIVWGPTVSR 114
T PP P P + P + PT ++
Sbjct: 762 TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTK 792
Score = 33.5 bits (75), Expect = 0.22
Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 21 LLLPLPPPAQGSSSSPRTPPAPARPP-------CARGGPSAPRHVCVWERAPPPSRSPRV 73
L+ PPA+ S S T P PA PP P + CV +AP S
Sbjct: 1000 LVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLS----- 1054
Query: 74 PRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTV 112
R + V+ +PP + S F PP ++ P + P V
Sbjct: 1055 GRGKDSVVEFPSPP-SDSDFPPPPPETELPLPPIEIPAV 1092
Score = 33.1 bits (74), Expect = 0.28
Identities = 41/174 (23%), Positives = 57/174 (32%), Gaps = 32/174 (18%)
Query: 16 PLWPLLLLPLP------PPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSR 69
P W +P+P PP + S P PP+P P P+A P S
Sbjct: 902 PKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTA-------SPTPDKSG 954
Query: 70 SPRVPRSRRQVLPGTAPPATP---------SGFEEGPPSSQYPWAIVWGPTVSREDGGDP 120
SP S+ G PP TP SG E P ++V T E G
Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPS 1014
Query: 121 NSANPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGRGE 174
P A P P ++ G +L + + + + GRG+
Sbjct: 1015 KE----------TLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGK 1058
Score = 28.9 bits (63), Expect = 5.3
Identities = 13/31 (41%), Positives = 15/31 (48%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPCARGGPSA 54
PLPPP P PP P P ++ PSA
Sbjct: 627 PLPPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657
Score = 28.5 bits (62), Expect = 6.9
Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 6/79 (7%)
Query: 26 PPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPP-PSRSPRVPRSRRQVLPGT 84
PPP + T AP PP P P + +APP P + P S + V P
Sbjct: 744 PPPLKIHQVQHITQVAPPTPP-----PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVV 798
Query: 85 APPATPSGFEEGPPSSQYP 103
A P+ PP+ + P
Sbjct: 799 TQAAPPTPTPPVPPAKKQP 817
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/122 (27%), Positives = 45/122 (36%), Gaps = 4/122 (3%)
Query: 16 PLWPLLLLPLP--PPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRV 73
P P + P P PPAQ ++ P PA+PP G + P PP + P
Sbjct: 301 PSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT-VKPPVQPPGT 358
Query: 74 PRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFA 133
+ Q L PPA +G E+ P A+ P V + P A P G
Sbjct: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418
Query: 134 AP 135
P
Sbjct: 419 KP 420
Score = 35.8 bits (81), Expect = 0.043
Identities = 28/95 (29%), Positives = 38/95 (40%), Gaps = 10/95 (10%)
Query: 31 GSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAPPATP 90
G + P P PA+PP + GP+ P A PPS+ P + Q PG A P+
Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS-AKPPSQQPGSTKPPPQ-QPGPAKPSPQ 522
Query: 91 SGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANP 125
PPS Q P ++ P+ A P
Sbjct: 523 QPGSTKPPSQQ--------PGSAKPSAQQPSPAKP 549
Score = 35.0 bits (79), Expect = 0.074
Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 6/77 (7%)
Query: 26 PPPAQ-GSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGT 84
PPP Q GS+ P P +PP + GP+ P PP + S +Q
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ----- 543
Query: 85 APPATPSGFEEGPPSSQ 101
PA PS + P SQ
Sbjct: 544 PSPAKPSAQQSTKPVSQ 560
Score = 33.1 bits (74), Expect = 0.28
Identities = 34/141 (24%), Positives = 49/141 (34%), Gaps = 16/141 (11%)
Query: 23 LPLPPPAQGSSSSPRTPPAPARPPCARGGP-----------SAPRHVCVWERAPPPSRSP 71
L P A G + +P P P + P + GP P + + PP P
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP 486
Query: 72 RVPRSRRQVLPGTA-PPATPSGFEEGPPSSQYP-WAIVWGPTVSREDGGDPNSANPGFLD 129
P ++ PG+A PP+ G + PP P P ++ P SA P
Sbjct: 487 AKPPPQQ---PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543
Query: 130 YGFAAPHGLATPHPNSDSMRG 150
A P + P S + G
Sbjct: 544 PSPAKPSAQQSTKPVSQTGSG 564
Score = 30.8 bits (68), Expect = 1.4
Identities = 25/87 (28%), Positives = 30/87 (34%), Gaps = 10/87 (11%)
Query: 24 PLPPPAQGSSSSPRTPPAPARPPCARGGP-------SAPRHVCVWERAP--PPSRSPRVP 74
P P Q SP P P + P + GP + P + P PPS+ P P
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG-P 476
Query: 75 RSRRQVLPGTAPPATPSGFEEGPPSSQ 101
PG A P PPS Q
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Score = 28.1 bits (61), Expect = 9.0
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 4/92 (4%)
Query: 40 PAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAPPATPSGF-EEGPP 98
P + PP A PS R + + + PP +S R P R PG + T F E
Sbjct: 67 PKGSVPPAAAESPSMHRKQEL-DSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKL 125
Query: 99 SSQYPWAIVWGPTVSREDGGDPNSAN--PGFL 128
+ P I + SR D + + ++ PGFL
Sbjct: 126 PGRSPSTISLKESKSRTDLKEEHKSSMMPGFL 157
Score = 28.1 bits (61), Expect = 9.0
Identities = 21/84 (25%), Positives = 32/84 (38%), Gaps = 20/84 (23%)
Query: 28 PAQGSSSSPRTP----PAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPG 83
P S S P P PAP++PP ++G P + PP+ + +P + P
Sbjct: 952 PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA-------PPAPAKSIPVKKETKAPA 1004
Query: 84 T---------APPATPSGFEEGPP 98
AP + E+ PP
Sbjct: 1005 AEKLEPKAEQAPTVKRTETEKKPP 1028
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.139 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,967,086
Number of Sequences: 37866
Number of extensions: 1264238
Number of successful extensions: 15348
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 225
Number of HSP's successfully gapped in prelim test: 1233
Number of HSP's that attempted gapping in prelim test: 9420
Number of HSP's gapped (non-prelim): 5497
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.