Search of human proteins with 24308516

Search of human proteins with 24308516

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24308516 tubulin tyrosine ligase [Homo sapiens]
         (377 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24308516 tubulin tyrosine ligase [Homo sapiens]                    771   0.0  
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ...   105   5e-23
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo...    98   1e-20
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo...    97   3e-20
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo...    88   1e-17
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ...    87   2e-17
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ...    87   3e-17
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo...    86   4e-17
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo...    85   1e-16
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ...    83   4e-16
gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ...    83   5e-16
gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H...    81   2e-15
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof...    80   4e-15
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho...    67   3e-11
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof...    49   7e-06
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo...    39   0.008
gi|222537745 schlafen family member 12-like [Homo sapiens]             32   1.2  
gi|40548403 decapping enzyme Dcp1b [Homo sapiens]                      31   1.6  
gi|31581534 tRNA isopentenyltransferase 1 [Homo sapiens]               30   4.6  
gi|148596977 zinc finger protein 31 [Homo sapiens]                     30   4.6  
gi|61966709 leucine rich repeat containing 67 [Homo sapiens]           30   4.6  
gi|4557761 mutS homolog 2 [Homo sapiens]                               29   6.1  
gi|54292123 lysosomal trafficking regulator [Homo sapiens]             29   6.1  

>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
          Length = 377

 Score =  771 bits (1992), Expect = 0.0
 Identities = 377/377 (100%), Positives = 377/377 (100%)

Query: 1   MYTFVVRDENSSVYAEVSRLLLATGHWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLVQ 60
           MYTFVVRDENSSVYAEVSRLLLATGHWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLVQ
Sbjct: 1   MYTFVVRDENSSVYAEVSRLLLATGHWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLVQ 60

Query: 61  LVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPI 120
           LVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPI
Sbjct: 61  LVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPI 120

Query: 121 SNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVH 180
           SNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVH
Sbjct: 121 SNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVH 180

Query: 181 VIQKYLEHPLLLEPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHL 240
           VIQKYLEHPLLLEPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHL
Sbjct: 181 VIQKYLEHPLLLEPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHL 240

Query: 241 TNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEP 300
           TNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEP
Sbjct: 241 TNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEP 300

Query: 301 AISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISSVFP 360
           AISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISSVFP
Sbjct: 301 AISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISSVFP 360

Query: 361 PPDVEQPQTQPAAFIKL 377
           PPDVEQPQTQPAAFIKL
Sbjct: 361 PPDVEQPQTQPAAFIKL 377


>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
           sapiens]
          Length = 592

 Score =  105 bits (263), Expect = 5e-23
 Identities = 87/286 (30%), Positives = 141/286 (49%), Gaps = 43/286 (15%)

Query: 60  QLVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPP 119
           Q +N++ G  KL RK  L K +K    +             Y T+L   +         P
Sbjct: 142 QQLNHHPGTTKLTRKDCLAKHLKHMRRM-------------YGTSLYQFI---------P 179

Query: 120 ISNSRTDEREFFLASYNRKKE--DGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQG 177
           ++    ++   F+A Y ++++    + + WI K +  ++G GILI S+     DFI +  
Sbjct: 180 LTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFK---DFIFDD- 235

Query: 178 QVHVIQKYLEHPLLLEPGHRKFDIRSWVLVD--HQYNIYLYREGVLRTASEPYHVDNFQD 235
            ++++QKY+ +PLL+  G  K D+R +V V       IY+Y+EG++R A+E + + N Q+
Sbjct: 236 -MYIVQKYISNPLLI--GRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQN 292

Query: 236 KTCHLTNHCIQKEYSKNYGKYEE----GNEMFFKEFNQYLTSALNITLESSILLQIKHII 291
              HLTN  I K    +Y K +E    G +     F  YL S      +   LL  K I 
Sbjct: 293 NYAHLTNSSINKS-GASYEKIKEVIGHGCKWTLSRFFSYLRS-----WDVDDLLLWKKIH 346

Query: 292 RNCLLSVEPAISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPA 337
           R  +L++     +       F+LFGFD ++D+ LK WL+EVN +PA
Sbjct: 347 RMVILTILAIAPSVPFAANCFELFGFDILIDDNLKPWLLEVNYSPA 392


>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
           sapiens]
          Length = 772

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 64/223 (28%), Positives = 113/223 (50%), Gaps = 19/223 (8%)

Query: 141 DGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVH-----VIQKYLEHPLLLEPG 195
           +G+ N+WI K  A ++G GI+      E+L  ++    V      V+QKY+E PLL+   
Sbjct: 274 EGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFG- 332

Query: 196 HRKFDIRSWVLVD--HQYNIYLYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKNY 253
             KFD+R W LV   +   ++ YR+  +R +++P+ + N  D + HL N+ IQK    + 
Sbjct: 333 -TKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNL-DNSVHLCNNSIQKHLENSC 390

Query: 254 GKYE---EGNEMFFKEFNQYLTSALNITLESSILLQ-IKHIIRNCLLSVEPAISTKHLPY 309
            ++      N    + F  +L         S+I++  +K  + + L + +  +  +    
Sbjct: 391 HRHPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKA-- 448

Query: 310 QSFQLFGFDFMVDEELKVWLIEVNGAPACAQK--LYAELCQGI 350
            SF+L+G DF+  E+ + WLIE+N +P  A    + A LC G+
Sbjct: 449 -SFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGV 490


>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
           1 [Homo sapiens]
          Length = 891

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 79/292 (27%), Positives = 132/292 (45%), Gaps = 51/292 (17%)

Query: 60  QLVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPP 119
           Q +N++ G  ++CRK  L +       ++     FP+ +  +P   +T   PA  G    
Sbjct: 160 QKINHFPGMSEICRKDLLAR------NMSRMLKMFPKDFRFFP---RTWCLPADWGD--- 207

Query: 120 ISNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQV 179
                       L +Y+R +++     +I K  +G +G+GI I+    E+       G+ 
Sbjct: 208 ------------LQTYSRSRKN---KTYICKPDSGCQGKGIFITRTVKEI-----KPGED 247

Query: 180 HVIQKYLEHPLLLEPGHRKFDIRSWVLVDH--QYNIYLYREGVLRTASEPYH---VDNFQ 234
            + Q Y+  P +++    KFD+R +VLV       I++Y EG+ R A+  Y     DN  
Sbjct: 248 MICQLYISKPFIIDGF--KFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLD 305

Query: 235 DKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTS-ALNITLESSILLQIKHIIRN 293
           D   HLTN+ I K  S        G++     F+ YL   + N+     I   I+ +I  
Sbjct: 306 DICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYLEDHSYNV---EQIWRDIEDVIIK 362

Query: 294 CLLSVEPAISTKH--------LPYQSFQLFGFDFMVDEELKVWLIEVNGAPA 337
            L+S  P I   +        L    F++ GFD ++D +LK WL+EVN +P+
Sbjct: 363 TLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPS 414


>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
           sapiens]
          Length = 1199

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 74/251 (29%), Positives = 124/251 (49%), Gaps = 27/251 (10%)

Query: 140 EDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVHVIQKYLEHPLLLEPGHRKF 199
           E      WI K  A A+G GI +  + S+L      + +  ++Q+YL  P L+     KF
Sbjct: 711 ESSSRQKWIVKPPASARGIGIQVIHKWSQL-----PKRRPLLVQRYLHKPYLISGS--KF 763

Query: 200 DIRSWVLVDHQ--YNIYLYREGVLRTASEPYH--VDNFQDKTCHLTNHCIQK---EYSKN 252
           D+R +V V       IYL+ +G++R AS  Y   + +  +K  HLTN+ + K   EY  N
Sbjct: 764 DLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQAN 823

Query: 253 YGKYE-EGNEMFFKEFNQYLTS-ALNITLESSILLQIKHIIRNCLLSVEPAISTK----- 305
             +   +G++   K    YL+   +N     +I  +IK ++   ++S EP +++      
Sbjct: 824 ADEMACQGHKWALKALWNYLSQKGVN---SDAIWEKIKDVVVKTIISSEPYVTSLLKMYV 880

Query: 306 HLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELC---QGIVDIAISSVFPPP 362
             PY   +LFGFD M+DE LK W++EVN +P+       ++    Q I D+   + F  P
Sbjct: 881 RRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLP 940

Query: 363 DVEQPQTQPAA 373
           + E   + P++
Sbjct: 941 NAEDIISSPSS 951


>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
           sapiens]
          Length = 1281

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 66/227 (29%), Positives = 122/227 (53%), Gaps = 34/227 (14%)

Query: 147 WIAKSSAGAKGEGILISSEASELLDFIDNQGQVHVIQKYLEHPLLLEPGHRKFDIRSWVL 206
           WI K  A ++G G+ + +  +++     +  +  ++ +Y+ +PLL++    KFD+R +VL
Sbjct: 177 WIVKPVASSRGRGVYLINNPNQI-----SLEENILVSRYINNPLLIDDF--KFDVRLYVL 229

Query: 207 VDHQYN---IYLYREGVLRTASEPYH--VDNFQDKTCHLTNHCIQKEYSKNYGKYEE--- 258
           V   Y+   IYLY EG+ R A+  Y     N +++  HLTN+ + K+ S +Y   ++   
Sbjct: 230 VT-SYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKK-SGDYVSCDDPEV 287

Query: 259 ---GNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEPAISTK---HLPYQS- 311
              GN+       +YL      T  ++++  ++ +I   ++S E AI+T     +P++S 
Sbjct: 288 EDYGNKWSMSAMLRYLKQEGRDT--TALMAHVEDLIIKTIISAELAIATACKTFVPHRSS 345

Query: 312 -FQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISS 357
            F+L+GFD ++D  LK WL+EVN +P+ A       C   +D+ I +
Sbjct: 346 CFELYGFDVLIDSTLKPWLLEVNLSPSLA-------CDAPLDLKIKA 385


>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
           sapiens]
          Length = 423

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 67/223 (30%), Positives = 108/223 (48%), Gaps = 26/223 (11%)

Query: 133 ASYNRKKED---GEGNVWIAKSSAGAKGEGILISSEASELL---------DFIDNQG-QV 179
           A YN   E+      + WI K    A+G+GI + ++ S++           F+     + 
Sbjct: 118 ADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEA 177

Query: 180 HVIQKYLEHPLLLEPGHRKFDIRSWVLVD--HQYNIYLYREGVLRTASEPY--HVDNFQD 235
           +VI  Y+ +PLL+  G RKFD+R +VLV        Y+Y+ G  R  +  Y        +
Sbjct: 178 YVISLYINNPLLI--GGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDN 235

Query: 236 KTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCL 295
              HLTN  IQK + ++Y  +  G +        YL S     + S +  +I  II   L
Sbjct: 236 MFVHLTNVAIQK-HGEDYN-HIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSL 293

Query: 296 LSVEPAIST-KHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPA 337
            +V P ++  KH     F+ +G+D ++D++LK WLIEVN +P+
Sbjct: 294 KAVAPVMNNDKHC----FECYGYDIIIDDKLKPWLIEVNASPS 332


>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
           sapiens]
          Length = 834

 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 64/232 (27%), Positives = 111/232 (47%), Gaps = 23/232 (9%)

Query: 141 DGEGNVWIAKSSAGAKGEG----ILISSEASELLDFID-----NQGQVHVIQKYLEHPLL 191
           DG  N+WI K +A ++G G    I+      E+L+        ++    V+QKY+E PLL
Sbjct: 325 DGLRNIWIIKPAAKSRGRGESPDIVCMDRVEEILELAAADHPLSRDNKWVVQKYIETPLL 384

Query: 192 LEPGHRKFDIRSWVLVD--HQYNIYLYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEY 249
           +     KFDIR W LV   +   I+ Y+E  LR +++ + +D   D   HL N+ +QK  
Sbjct: 385 I--CDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKL-DSAIHLCNNAVQKYL 441

Query: 250 SKNYGK---YEEGNEMFFKEFNQYLTSALNITLESSILL-QIKHIIRNCLLSVEPAISTK 305
             + G+       N      F +YL       +  S++   +K  I + +   +  +  +
Sbjct: 442 KNDVGRSPLLPAHNMWTSTRFQEYLQRQGRGAVWGSVIYPSMKKAIAHAMKVAQDHVEPR 501

Query: 306 HLPYQSFQLFGFDFMVDEELKVWLIEVNGAPAC--AQKLYAELCQGIVDIAI 355
                SF+L+G DF++  + + WLIE+N +P    +  + A+LC  + +  I
Sbjct: 502 K---NSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQLCAQVQEDTI 550


>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
           sapiens]
          Length = 459

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 81/302 (26%), Positives = 132/302 (43%), Gaps = 69/302 (22%)

Query: 60  QLVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPP 119
           Q +N++ G  ++CRK  L + +    +L      +P  Y I+P   +T   PA  G    
Sbjct: 139 QKINHFPGMTEICRKDLLARNLNRMYKL------YPSEYNIFP---RTWCLPADYGD--- 186

Query: 120 ISNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQV 179
                         SY R+++      +I K  +G +G GI I+    E+       G+ 
Sbjct: 187 ------------FQSYGRQRK---ARTYICKPDSGCQGRGIFITRNPREI-----KPGEH 226

Query: 180 HVIQKYLEHPLLLEPGHRKFDIRSWVLVDH--QYNIYLYREGVLRTASEPYHVD--NFQD 235
            + Q+Y+  PLL++    KFD+R +VL+       I+ Y EG+ R A+ PY     N  D
Sbjct: 227 MICQQYISKPLLIDGF--KFDMRVYVLITSCDPLRIFTYEEGLARFATTPYMEPSHNNLD 284

Query: 236 KTC-HLTNHCIQKEYSKNYGKYEEGNEMFFKEF---NQYLTSALNITLES------SILL 285
             C HLTN+ I K            NE F ++    ++   S LNI L+        +  
Sbjct: 285 NVCMHLTNYAINKH-----------NENFVRDGAVGSKRKLSTLNIWLQEHSYNPGELWG 333

Query: 286 QIKHIIRNCLLSVEPAISTKHLPY----------QSFQLFGFDFMVDEELKVWLIEVNGA 335
            I+ II   ++S    +   +               F++ GFD ++D +LK WL+EVN +
Sbjct: 334 DIEDIIIKTIISAHSVLRHNYRTCFPQYLNGGTCACFEILGFDILLDHKLKPWLLEVNHS 393

Query: 336 PA 337
           P+
Sbjct: 394 PS 395


>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
           sapiens]
          Length = 887

 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 81/316 (25%), Positives = 149/316 (47%), Gaps = 61/316 (19%)

Query: 60  QLVNYYRGADKLCRK----ASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNG 115
           Q +N++ G  ++CRK     ++ K+IK+ P            Y   P   +T + PA+  
Sbjct: 93  QRINHFPGMGEICRKDFLARNMTKMIKSRPL----------DYTFVP---RTWIFPAEY- 138

Query: 116 IQPPISNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDN 175
                      + + ++    +K++      +I K + GA G GI +     +L      
Sbjct: 139 ----------TQFQNYVKELKKKRKQ---KTFIVKPANGAMGHGISLIRNGDKL------ 179

Query: 176 QGQVH-VIQKYLEHPLLLEPGHRKFDIRSWVLVDH--QYNIYLYREGVLRTASEPYHVDN 232
             Q H ++Q+Y+E P L+E G+ KFD+R ++LV       I+LY +G++R  +E Y   N
Sbjct: 180 PSQDHLIVQEYIEKPFLME-GY-KFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPN 237

Query: 233 FQDKT---CHLTNHCIQK--EYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQI 287
             + T    HLTN+ + K  E+ +      +G++   K F ++L +  N    +     I
Sbjct: 238 ESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQA--NQHDVAKFWSDI 295

Query: 288 KHIIRNCLLSVEPAISTKHL---PYQS-------FQLFGFDFMVDEELKVWLIEVNGAPA 337
             ++   L+  EP +   +    P Q        F++ GFD ++D +LK WL+E+N AP+
Sbjct: 296 SELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPS 355

Query: 338 CA--QKLYAELCQGIV 351
               QK+  ++ +G++
Sbjct: 356 FGTDQKIDYDVKRGVL 371


>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
           sapiens]
          Length = 439

 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 64/206 (31%), Positives = 102/206 (49%), Gaps = 33/206 (16%)

Query: 144 GNVWIAKSSAGAKGEGILISSEASELLDF------IDNQG-----QVHVIQKYLEHPLLL 192
           G  WI K  A ++G+GI +     +++D+       D+Q      + +V Q+Y+E+P L+
Sbjct: 161 GITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLI 220

Query: 193 EPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKN 252
             G RKFD+R +VLV   +   L   G  R             +  HLTN  +QK     
Sbjct: 221 --GGRKFDLRVYVLVMSVFAECLLWSGHRR-------------QDVHLTNVAVQKTSPDY 265

Query: 253 YGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEPAI-STKHLPYQS 311
           + K  +G +   + F QYL S        ++   I +I    L SV+  I S KH     
Sbjct: 266 HPK--KGCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVIISDKHC---- 319

Query: 312 FQLFGFDFMVDEELKVWLIEVNGAPA 337
           F+L+G+D ++D++LK WL+EVN +P+
Sbjct: 320 FELYGYDILIDQDLKPWLLEVNASPS 345


>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
           sapiens]
          Length = 800

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 78/310 (25%), Positives = 137/310 (44%), Gaps = 48/310 (15%)

Query: 62  VNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPIS 121
           VN + G  ++ RK +L + ++T   L      FPE Y  YP +   P             
Sbjct: 272 VNKFPGMTEMVRKITLSRAVRTMQNL------FPEEYNFYPRSWILP------------- 312

Query: 122 NSRTDEREFFLASYNRKKEDGEG--NVWIAKSSAGAKGEGILISSEASELLDFIDNQGQV 179
               DE + F+A     K+D       +I K   G +G+GI +  + S++      Q + 
Sbjct: 313 ----DEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRP 368

Query: 180 HVIQKYLEHPLLLEPGHRKFDIRSWVLVDH--QYNIYLYREGVLRTASEPYHVD---NFQ 234
            V+Q+Y+  PLL++    KFDIR +VL+       IY+ ++G+ R  +EPY      N  
Sbjct: 369 AVVQEYICKPLLIDK--LKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLH 426

Query: 235 DKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLE-SSILLQIKHIIRN 293
               HLTN+ +   +S N+   +  +    + F+  L    +  ++   +   I  ++  
Sbjct: 427 RIFMHLTNYSLNI-HSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIK 485

Query: 294 CLLSVEPAISTKHLPYQS-----------FQLFGFDFMVDEELKVWLIEVNGAPACAQKL 342
            ++++ P +      YQS           FQ+ GFD ++ + LK  L+EVN  P+   + 
Sbjct: 486 TVIALTPELKVF---YQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEH 542

Query: 343 YAELCQGIVD 352
             EL  G+ +
Sbjct: 543 EHELSPGVFE 552


>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
           1 [Homo sapiens]
          Length = 673

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 67/236 (28%), Positives = 115/236 (48%), Gaps = 39/236 (16%)

Query: 127 EREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELL-----------DFIDN 175
           ERE F   ++      E  +WI K +A  +G+GI +     E+            D I +
Sbjct: 296 EREAFFTLFD------ETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHH 349

Query: 176 QG-----QVHVIQKYLEHPLLLEPGHRKFDIRSWVLV--DHQYNIYLYREGVLRTASEPY 228
           +      Q  V+Q+Y+++PLL++   RKFD+RS++L+     Y I+ +  G  R     Y
Sbjct: 350 KTPFRGPQARVVQRYIQNPLLVDG--RKFDVRSYLLIACTTPYMIF-FGHGYARLTLSLY 406

Query: 229 HVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSAL-------NITLES 281
              +  D   HLTN  +QK+ S  Y   +E      +  N+Y++             + +
Sbjct: 407 DPHS-SDLGGHLTNQFMQKK-SPLYMLLKEHTVWSMEHLNRYISDTFWKARGLAKDWVFT 464

Query: 282 SILLQIKHIIRNCLLSVEPAISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPA 337
           ++  +++ I+ +C L+ +P +  K L Y  F L G DF++D+  KVWL+E+N  PA
Sbjct: 465 TLKKRMQQIMAHCFLAAKPKLDCK-LGY--FDLIGCDFLIDDNFKVWLLEMNSNPA 517


>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
           sapiens]
          Length = 538

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 54/191 (28%), Positives = 87/191 (45%), Gaps = 32/191 (16%)

Query: 62  VNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPIS 121
           VN + G  ++ RK +L + ++T   L      FPE Y  YP +   P             
Sbjct: 272 VNKFPGMTEMVRKITLSRAVRTMQNL------FPEEYNFYPRSWILP------------- 312

Query: 122 NSRTDEREFFLASYNRKKEDGEG--NVWIAKSSAGAKGEGILISSEASELLDFIDNQGQV 179
               DE + F+A     K+D       +I K   G +G+GI +  + S++      Q + 
Sbjct: 313 ----DEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRP 368

Query: 180 HVIQKYLEHPLLLEPGHRKFDIRSWVLVDH--QYNIYLYREGVLRTASEPYH---VDNFQ 234
            V+Q+Y+  PLL++    KFDIR +VL+       IY+ ++G+ R  +EPY      N  
Sbjct: 369 AVVQEYICKPLLIDK--LKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLH 426

Query: 235 DKTCHLTNHCI 245
               HLTN+ +
Sbjct: 427 RIFMHLTNYSL 437


>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
           2 [Homo sapiens]
          Length = 404

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 29/164 (17%)

Query: 127 EREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELL-----------DFIDN 175
           ERE F   ++      E  +WI K +A  +G+GI +     E+            D I +
Sbjct: 223 EREAFFTLFD------ETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHH 276

Query: 176 Q-----GQVHVIQKYLEHPLLLEPGHRKFDIRSWVLV--DHQYNIYLYREGVLRTASEPY 228
           +      Q  V+Q+Y+++PLL++   RKFD+RS++L+     Y I+ +  G  R     Y
Sbjct: 277 KTPFRGPQARVVQRYIQNPLLVD--GRKFDVRSYLLIACTTPYMIF-FGHGYARLTLSLY 333

Query: 229 HVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLT 272
              +  D   HLTN  +QK+ S  Y   +E      +  N+Y++
Sbjct: 334 D-PHSSDLGGHLTNQFMQKK-SPLYMLLKEHTVWSMEHLNRYIS 375


>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
           2 [Homo sapiens]
          Length = 584

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 8/59 (13%)

Query: 287 IKHIIRNCLLSVEPAISTKH--------LPYQSFQLFGFDFMVDEELKVWLIEVNGAPA 337
           I+ +I   L+S  P I   +        L    F++ GFD ++D +LK WL+EVN +P+
Sbjct: 49  IEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPS 107


>gi|222537745 schlafen family member 12-like [Homo sapiens]
          Length = 617

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 17/56 (30%), Positives = 25/56 (44%)

Query: 77  LVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPISNSRTDEREFFL 132
           + K+   SPE   SC +   S VIYP +     A     ++  +SN    E + FL
Sbjct: 542 MTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKDLEKALSNILPKENQIFL 597


>gi|40548403 decapping enzyme Dcp1b [Homo sapiens]
          Length = 617

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 36/165 (21%), Positives = 65/165 (39%), Gaps = 17/165 (10%)

Query: 55  EPGLVQLVNYYRGADKLCRKASLVKLIKTSPELAESC---TWFPESYVIY-----PTNLK 106
           +PG    +   RG     R  +L + ++++P  A  C   T  P S         PT++ 
Sbjct: 333 QPGSPHNIGTSRGVQNASRTQNLFEKLQSTPGAANKCDPSTPAPASSAALNRSRAPTSV- 391

Query: 107 TPVAPAQNGIQPP---ISNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILIS 163
           TPVAP +   QPP    + S   +     A    +       + I+ S  G+   G++  
Sbjct: 392 TPVAPGKGLAQPPQAYFNGSLPPQTVGHQAHGREQSTLPRQTLPISGSQTGS--SGVISP 449

Query: 164 SEASELLDFIDNQGQVHVIQK---YLEHPLLLEPGHRKFDIRSWV 205
            E  + L  +  + Q+H   +     + P+L +       + SW+
Sbjct: 450 QELLKKLQIVQQEQQLHASNRPALAAKFPVLAQSSGTGKPLESWI 494


>gi|31581534 tRNA isopentenyltransferase 1 [Homo sapiens]
          Length = 467

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query: 246 QKEYSKNYGKYEEG--NEMFFKEFNQYLTSALNITLESSILLQIKHI 290
           QK  S+N   Y+ G    + FKEF++YL +    TLE+S  L  K I
Sbjct: 265 QKNVSENSQDYQHGIFQSIGFKEFHEYLITEGKCTLETSNQLLKKGI 311


>gi|148596977 zinc finger protein 31 [Homo sapiens]
          Length = 1043

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 6/80 (7%)

Query: 9   ENSSVYAEVSRLLLATGHWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGA 68
           +NS VY  ++  L A G  + L +   RF  +L    +    +  H PG      +Y   
Sbjct: 512 QNSQVYRAIAERLCALGFLRTLEQCRYRFKNLLRSYRK---AKSSHPPGTCP---FYEEL 565

Query: 69  DKLCRKASLVKLIKTSPELA 88
           D L R  + V+ + T  E A
Sbjct: 566 DSLMRARAAVRAMGTVREAA 585


>gi|61966709 leucine rich repeat containing 67 [Homo sapiens]
          Length = 228

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 9/28 (32%), Positives = 20/28 (71%)

Query: 318 DFMVDEELKVWLIEVNGAPACAQKLYAE 345
           +F++++ +K+W I++NG P C +  Y +
Sbjct: 187 EFLLNKLMKLWKIDLNGNPVCLKPKYRD 214


>gi|4557761 mutS homolog 2 [Homo sapiens]
          Length = 934

 Score = 29.3 bits (64), Expect = 6.1
 Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 7/106 (6%)

Query: 164 SEASELLDFIDNQGQVHVIQKYLEHPLLLEPGHRKFDIRSWVLVDHQYNIYLYREGVLRT 223
           SE  E+++ ++ + Q  +I    +  L L+PG ++  + S     + + +    E VLR 
Sbjct: 479 SELREIMNDLEKKMQSTLISAARD--LGLDPG-KQIKLDSSAQFGYYFRVTCKEEKVLRN 535

Query: 224 ASEPYHVDNFQDKTCHLTNH---CIQKEYSKNYGKYEEGNEMFFKE 266
                 VD  Q      TN     + +EY+KN  +YEE  +   KE
Sbjct: 536 NKNFSTVD-IQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKE 580


>gi|54292123 lysosomal trafficking regulator [Homo sapiens]
          Length = 3801

 Score = 29.3 bits (64), Expect = 6.1
 Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 13/115 (11%)

Query: 151 SSAGAKGEGILISSEASELL----------DFIDNQGQVHVIQKYLEHPLLLEPGHRKFD 200
           SS   + +GIL SS + +LL          +F+  + ++H IQ       L++ G+    
Sbjct: 668 SSPSYRFQGILPSSGSEDLLWKWDALKAYQNFVFEEDRLHSIQIANHICNLIQKGNI--- 724

Query: 201 IRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKNYGK 255
           +  W L ++ +N  L R   L    +   V + Q   C   N C+ ++  + Y K
Sbjct: 725 VVQWKLYNYIFNPVLQRGVELAHHCQHLSVTSAQSHVCSHHNQCLPQDVLQIYVK 779


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,126,371
Number of Sequences: 37866
Number of extensions: 679007
Number of successful extensions: 1439
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1388
Number of HSP's gapped (non-prelim): 25
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.