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Search of human proteins with 24308382
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308382 leukocyte receptor cluster member 8 [Homo sapiens]
(800 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308382 leukocyte receptor cluster member 8 [Homo sapiens] 1653 0.0
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 62 2e-09
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 62 2e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 59 1e-08
gi|146134388 YLP motif containing 1 [Homo sapiens] 59 2e-08
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 52 2e-06
gi|57864582 hornerin [Homo sapiens] 52 2e-06
gi|19923191 minichromosome maintenance complex component 3 assoc... 51 5e-06
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 50 8e-06
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 48 3e-05
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 48 3e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 48 3e-05
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 48 4e-05
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 48 4e-05
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 48 4e-05
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 47 5e-05
gi|21361320 TRK-fused [Homo sapiens] 47 5e-05
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 47 5e-05
gi|56090139 TRK-fused [Homo sapiens] 47 5e-05
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 47 5e-05
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 47 5e-05
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 47 7e-05
gi|55750053 atrophin-1 [Homo sapiens] 47 9e-05
gi|55750041 atrophin-1 [Homo sapiens] 47 9e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 47 9e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 46 2e-04
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 46 2e-04
gi|62122917 filaggrin family member 2 [Homo sapiens] 45 2e-04
gi|8923842 forkhead box J2 [Homo sapiens] 45 2e-04
gi|150417989 cyclin K isoform 1 [Homo sapiens] 45 2e-04
>gi|24308382 leukocyte receptor cluster member 8 [Homo sapiens]
Length = 800
Score = 1653 bits (4281), Expect = 0.0
Identities = 800/800 (100%), Positives = 800/800 (100%)
Query: 1 MAANVGDQRSTDWSSQYSMVAGAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAK 60
MAANVGDQRSTDWSSQYSMVAGAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAK
Sbjct: 1 MAANVGDQRSTDWSSQYSMVAGAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAK 60
Query: 61 SSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMA 120
SSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMA
Sbjct: 61 SSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMA 120
Query: 121 GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLN 180
GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLN
Sbjct: 121 GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLN 180
Query: 181 SGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQK 240
SGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQK
Sbjct: 181 SGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQK 240
Query: 241 RPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEYVERC 300
RPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEYVERC
Sbjct: 241 RPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEYVERC 300
Query: 301 FTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAA 360
FTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAA
Sbjct: 301 FTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAA 360
Query: 361 SSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSR 420
SSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSR
Sbjct: 361 SSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSR 420
Query: 421 SRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRG 480
SRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRG
Sbjct: 421 SRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRG 480
Query: 481 KRHDLAPTKRSRKKMAALECEDPERELKKQKRAARFQHGHSRRLRLEPLVLQMSSLESSG 540
KRHDLAPTKRSRKKMAALECEDPERELKKQKRAARFQHGHSRRLRLEPLVLQMSSLESSG
Sbjct: 481 KRHDLAPTKRSRKKMAALECEDPERELKKQKRAARFQHGHSRRLRLEPLVLQMSSLESSG 540
Query: 541 ADPDWQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKCHWKEKQDYAFAC 600
ADPDWQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKCHWKEKQDYAFAC
Sbjct: 541 ADPDWQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKCHWKEKQDYAFAC 600
Query: 601 EQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAENLPGNVG 660
EQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAENLPGNVG
Sbjct: 601 EQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAENLPGNVG 660
Query: 661 EFTAYRILYYIFTKNSGDITTELAYLTRELKADPCVAHALALRTAWALGNYHRFFRLYCH 720
EFTAYRILYYIFTKNSGDITTELAYLTRELKADPCVAHALALRTAWALGNYHRFFRLYCH
Sbjct: 661 EFTAYRILYYIFTKNSGDITTELAYLTRELKADPCVAHALALRTAWALGNYHRFFRLYCH 720
Query: 721 APCMSGYLVDKFADRERKVALKAMIKTFRPALPVSYLQAELAFEGEAACRAFLEPLGLAY 780
APCMSGYLVDKFADRERKVALKAMIKTFRPALPVSYLQAELAFEGEAACRAFLEPLGLAY
Sbjct: 721 APCMSGYLVDKFADRERKVALKAMIKTFRPALPVSYLQAELAFEGEAACRAFLEPLGLAY 780
Query: 781 TGPDNSSIDCRLSLAQLSAF 800
TGPDNSSIDCRLSLAQLSAF
Sbjct: 781 TGPDNSSIDCRLSLAQLSAF 800
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 62.4 bits (150), Expect = 2e-09
Identities = 85/335 (25%), Positives = 114/335 (34%), Gaps = 66/335 (19%)
Query: 7 DQRSTDWSSQYSMVAGAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAKSSSNGP 66
D S W + + A A G + H P G++GG + + P
Sbjct: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAP------------MSPGSSGGGGQPLARTP 378
Query: 67 VASAQYVSQAE--------ASALQQQQYYQWYQQYNYAYPYSYY-------YPMSMY--- 108
S+ + + QQQ Q + YP Y YPM+M
Sbjct: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438
Query: 109 -------------QSYGS--PSQYGMAGSYGSATPQQPSAPQHQGTLNQ-PPVPGMDESM 152
YG PS YG G Q P Q Q +Q PP
Sbjct: 439 QSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQP 498
Query: 153 SYQAPPQ----QLPSAQPP---QPSNPPHGAHTLNSGPQPGTAPAT-QHSQAGP--ATGQ 202
SYQ PQ QL S+QPP QPS PP H + P P T QH Q+ P + Q
Sbjct: 499 SYQQQPQSQPPQLQSSQPPYSQQPSQPP---HQQSPAPYPSQQSTTQQHPQSQPPYSQPQ 555
Query: 203 AYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKR-----PFAVTTQSFGSNAEGQ 257
A P+ +P +P P P + + + P ++ SFGS A
Sbjct: 556 AQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSA 615
Query: 258 HSGFGPQPNPE--KVQNHSGSSARGNLSGKPDDWP 290
S + E + S S+ +LSG DD P
Sbjct: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP 650
Score = 41.2 bits (95), Expect = 0.004
Identities = 65/286 (22%), Positives = 100/286 (34%), Gaps = 40/286 (13%)
Query: 17 YSMVAGAGRENGMETPMHENP---EWEKARQALASISKSGAAGGSAKSSSNGPVASAQYV 73
YS AG G N P P +++ R + + G+ + + +
Sbjct: 1260 YSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMY 1319
Query: 74 SQAEASALQQQQYYQWYQQYNYAY-----PYSYYYPM---SMYQSYGSPSQYGMAGSYGS 125
S + QQQQ Q + Y + P +P +MYQ + M G+YG
Sbjct: 1320 SPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYG- 1378
Query: 126 ATPQQPSAPQHQGTLNQPPVP-GMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQ 184
P A +H+G + P G + Q PP Q PQP++ A P
Sbjct: 1379 -----PPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQ------PQPASQQQAAQ-----PS 1422
Query: 185 PGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLW----NRMKPAPGTGGLKFNIQK 240
P Q+ A PAT A T PA + Q + +R+ PGT Q
Sbjct: 1423 PQQDVYNQYGNAYPATATA---ATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQ----QN 1475
Query: 241 RPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKP 286
P + ++AE G Q + N++ + G+ P
Sbjct: 1476 MPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGP 1521
Score = 33.5 bits (75), Expect = 0.80
Identities = 46/183 (25%), Positives = 70/183 (38%), Gaps = 24/183 (13%)
Query: 59 AKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYS---YYYPMSMYQ-SYGSP 114
++ + P Q A ++ QQ Y Q Q + YS + P + Q S+GS
Sbjct: 552 SQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ 611
Query: 115 --SQYGMAGSYG-------SATPQQPSAPQHQGTLNQPPV-------PGMDES-MSYQAP 157
S M S G S + S P G+++ P+ PG+ S +S
Sbjct: 612 ASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQG 671
Query: 158 PQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPAT-QHSQAGPATGQAYGPHTYTEPAKPK 216
Q P+ P P PH P P +PA+ S++GP + A + P +P
Sbjct: 672 EQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQM--PPRPP 729
Query: 217 KGQ 219
GQ
Sbjct: 730 SGQ 732
Score = 30.8 bits (68), Expect = 5.2
Identities = 46/191 (24%), Positives = 58/191 (30%), Gaps = 49/191 (25%)
Query: 114 PSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPP 173
PS G G TPQ S+ +G +PP P P Q+P SN
Sbjct: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPA-------STPHSQIPPLPGMSRSNSV 1185
Query: 174 HGAHTLNSG------------PQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQL 221
N G P PG P+ T G +Y EP K G
Sbjct: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMN-------TSDMMGRMSY-EPNKDPYGS-- 1235
Query: 222 WNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGN 281
M+ APG + F S+ +G + G G P G+ A G
Sbjct: 1236 ---MRKAPG----------------SDPFMSSGQGPNGGMG-DPYSRAAGPGLGNVAMGP 1275
Query: 282 LSGKPDDWPQD 292
P P D
Sbjct: 1276 RQHYPYGGPYD 1286
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 62.4 bits (150), Expect = 2e-09
Identities = 85/335 (25%), Positives = 114/335 (34%), Gaps = 66/335 (19%)
Query: 7 DQRSTDWSSQYSMVAGAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAKSSSNGP 66
D S W + + A A G + H P G++GG + + P
Sbjct: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAP------------MSPGSSGGGGQPLARTP 378
Query: 67 VASAQYVSQAE--------ASALQQQQYYQWYQQYNYAYPYSYY-------YPMSMY--- 108
S+ + + QQQ Q + YP Y YPM+M
Sbjct: 379 QPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438
Query: 109 -------------QSYGS--PSQYGMAGSYGSATPQQPSAPQHQGTLNQ-PPVPGMDESM 152
YG PS YG G Q P Q Q +Q PP
Sbjct: 439 QSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQP 498
Query: 153 SYQAPPQ----QLPSAQPP---QPSNPPHGAHTLNSGPQPGTAPAT-QHSQAGP--ATGQ 202
SYQ PQ QL S+QPP QPS PP H + P P T QH Q+ P + Q
Sbjct: 499 SYQQQPQSQPPQLQSSQPPYSQQPSQPP---HQQSPAPYPSQQSTTQQHPQSQPPYSQPQ 555
Query: 203 AYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKR-----PFAVTTQSFGSNAEGQ 257
A P+ +P +P P P + + + P ++ SFGS A
Sbjct: 556 AQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSA 615
Query: 258 HSGFGPQPNPE--KVQNHSGSSARGNLSGKPDDWP 290
S + E + S S+ +LSG DD P
Sbjct: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP 650
Score = 33.5 bits (75), Expect = 0.80
Identities = 46/183 (25%), Positives = 70/183 (38%), Gaps = 24/183 (13%)
Query: 59 AKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYS---YYYPMSMYQ-SYGSP 114
++ + P Q A ++ QQ Y Q Q + YS + P + Q S+GS
Sbjct: 552 SQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQ 611
Query: 115 --SQYGMAGSYG-------SATPQQPSAPQHQGTLNQPPV-------PGMDES-MSYQAP 157
S M S G S + S P G+++ P+ PG+ S +S
Sbjct: 612 ASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQG 671
Query: 158 PQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPAT-QHSQAGPATGQAYGPHTYTEPAKPK 216
Q P+ P P PH P P +PA+ S++GP + A + P +P
Sbjct: 672 EQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQM--PPRPP 729
Query: 217 KGQ 219
GQ
Sbjct: 730 SGQ 732
Score = 30.8 bits (68), Expect = 5.2
Identities = 46/191 (24%), Positives = 58/191 (30%), Gaps = 49/191 (25%)
Query: 114 PSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPP 173
PS G G TPQ S+ +G +PP P P Q+P SN
Sbjct: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPA-------STPHSQIPPLPGMSRSNSV 1185
Query: 174 HGAHTLNSG------------PQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQL 221
N G P PG P+ T G +Y EP K G
Sbjct: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMN-------TSDMMGRMSY-EPNKDPYGS-- 1235
Query: 222 WNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGN 281
M+ APG + F S+ +G + G G P G+ A G
Sbjct: 1236 ---MRKAPG----------------SDPFMSSGQGPNGGMG-DPYSRAAGPGLGNVAMGP 1275
Query: 282 LSGKPDDWPQD 292
P P D
Sbjct: 1276 RQHYPYGGPYD 1286
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 59.3 bits (142), Expect = 1e-08
Identities = 98/421 (23%), Positives = 147/421 (34%), Gaps = 73/421 (17%)
Query: 125 SATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQ-PSNPPHGAH-TLNSG 182
SAT PS P+ T +PP P + + PQ L + Q P NPP A T +
Sbjct: 346 SATRPSPS-PERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRS 404
Query: 183 P--QPGTAPATQHSQAGPATGQA--YGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNI 238
P P P + S++ P + Q H + P PK PAPG+
Sbjct: 405 PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA--------PAPGSH------ 450
Query: 239 QKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEYVE 298
+ S+ ++ G + +K +H+ S G P K
Sbjct: 451 ---------REISSSPTSKNRSHG-RAKRDKSHSHTPSRRMGRSRS-----PATAKRGRS 495
Query: 299 RCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWE 358
R T + + R+ + + R W R P R + SP++ W
Sbjct: 496 RSRTPTKRGHSRSRSPQWRRSRSAQR----------WGRSRSP--QRRGRSRSPQRPGWS 543
Query: 359 AASSLHPPRGAGSATRGGG---APSQRG-----TPGAGGAGRARGNSFTKFGNRNVFMKD 410
+ + + SA RG +P+ RG TP G R+R + + +R +
Sbjct: 544 RSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRR 603
Query: 411 NSSS---------SSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPK 461
+ S S T +R RS +RSP R RRS S S + S R P +
Sbjct: 604 SRSRTPARRGRSRSRTPARRRSRTRSPVR--RRSRSRSPARRSGRSRS------RTPARR 655
Query: 462 GRGGRGAHMDRGRGRAQRGKRHDLAPTKRSRKKMAALECEDPERELKKQKRAARFQHGHS 521
GR RGR R++ R R+ + P R + + R HS
Sbjct: 656 GRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHS 715
Query: 522 R 522
R
Sbjct: 716 R 716
Score = 50.4 bits (119), Expect = 6e-06
Identities = 71/292 (24%), Positives = 103/292 (35%), Gaps = 33/292 (11%)
Query: 223 NRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARG-- 280
+R+ P G ++ +P A GS++ + P+ P + ++ S S RG
Sbjct: 1589 SRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
Query: 281 -----NLSGKPDDWP---------QDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQ 326
+ P+ P + E + T + E K L R +
Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSR 1708
Query: 327 DGSAYTIDWSREPLPGLTREPVAESP----KKKRWEAASSLHPPRGAGSATRGGGAPSQR 382
S+ SR P P R P SP K + S PR + +R G +PS
Sbjct: 1709 SASSSPETRSRTP-PRHRRSPSVSSPEPAEKSRSSRRRRSASSPR-TKTTSRRGRSPS-- 1764
Query: 383 GTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSD 442
P G R+R S + R +D S SS + SR R SRS +R RR S
Sbjct: 1765 --PKPRGLQRSRSRS-RREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYH 1821
Query: 443 SSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRGKRHDLAPTKRSRKK 494
S P + + R RG R + R AP KRSR +
Sbjct: 1822 SR------SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSR 1867
Score = 41.6 bits (96), Expect = 0.003
Identities = 107/490 (21%), Positives = 173/490 (35%), Gaps = 97/490 (19%)
Query: 45 ALASISKSGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYP 104
ALA++S +G+ G+ +++N P S+ QA ASA N P S +
Sbjct: 2305 ALAALSLTGS--GTPPTAANYP--SSSRTPQAPASA-------------NLVGPRSAHAT 2347
Query: 105 MSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSA 164
+ + GS + +A + ++ P+ T + P+ + +PP +
Sbjct: 2348 APVNIA-GSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRAR 2406
Query: 165 QPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKP------KKG 218
PS P T P P S+ G A Q+ P +P P +
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPS-------SRMGQAPSQSLLPPAQDQPRSPVPSAFSDQS 2459
Query: 219 QQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSA 278
+ L + P G+ L A TT S G H+G P P + G
Sbjct: 2460 RCLIAQTTPVAGSQSLSSGA----VATTTSS-----AGDHNGMLSVPAPGVPHSDVGEPP 2510
Query: 279 RGNLSGKPDDWP-----QDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTI 333
+ +P ++ + ++ S + + +GS+ +
Sbjct: 2511 ASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570
Query: 334 DWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRA 393
+P L R P SP EA PP P++R + + +
Sbjct: 2571 ----QPEVALKRVP---SPTPAPKEAVREGRPPEPT---------PAKRKRRSSSSSSSS 2614
Query: 394 RGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPT-------------------RHFRR 434
+S + + + +SSSSS+ S S SSS SP+ RR
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR 2674
Query: 435 S-------DSHSDSDS-SYSGNECHPVGRR--NPPPKGRGGRGAHMDRGRGRAQRGKRHD 484
S DS DS S SYS PV RR +P P R + + +RG R QRG
Sbjct: 2675 SRSPRKPIDSLRDSRSLSYS-----PVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR- 2728
Query: 485 LAPTKRSRKK 494
+P+ + R++
Sbjct: 2729 -SPSHKRRRE 2737
Score = 40.0 bits (92), Expect = 0.009
Identities = 102/464 (21%), Positives = 166/464 (35%), Gaps = 99/464 (21%)
Query: 105 MSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPV--------PGMDESMSYQA 156
MS QS SP + + S+P+ + L + P PG+ +
Sbjct: 1396 MSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSG--T 1453
Query: 157 PPQQLPSAQPPQ----PSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEP 212
P + S P P P G +S P+P P T ++ P
Sbjct: 1454 PSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRS-------------RSP 1500
Query: 213 AKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQN 272
+ P+ + + P G + ++ ++ A T P ++
Sbjct: 1501 SSPELNNKC---LTPQRERSGSESSVDQKTVART--------------------PLGQRS 1537
Query: 273 HSGSSARGNLSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYT 332
SGSS L KP PQ+ E + S + K +T L++ R + GS+
Sbjct: 1538 RSGSSQ--ELDVKPSASPQERSE-------SDSSPDSKAKTRTPLRQ----RSRSGSSPE 1584
Query: 333 IDWSREPLPGLTREPVAESPKKK-----RWEAASSLHP------PRG------AGSATRG 375
+D P +R + K K R ++ S P PR +GS+++G
Sbjct: 1585 VDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKG 1644
Query: 376 GGAPSQRGTPGAGGAGRARGNSFT-KFGNRNVFMKDNSSSSSTDSRSRSSSRSP--TRHF 432
G PS G+ + S T + G+R+ + + S T R RSS SP TR
Sbjct: 1645 RG-PSPEGSSSTESSPEHPPKSRTARRGSRS--SPEPKTKSRTPPRRRSSRSSPELTRKA 1701
Query: 433 RRS-DSHSDSDSSYSGNECHPVGRRNP----------PPKGRGGRGAHMDRGRGRAQRGK 481
R S S S S S + + P RR+P R R A R + ++RG+
Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761
Query: 482 RHDLAPTKRSRKKMAALECEDPERELKKQKRAARFQHGHSRRLR 525
+P R ++ + + R +++ R+ Q RR R
Sbjct: 1762 --SPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQR 1803
Score = 36.6 bits (83), Expect = 0.095
Identities = 91/427 (21%), Positives = 143/427 (33%), Gaps = 69/427 (16%)
Query: 120 AGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNP-PHGAHT 178
+GS + +AP+ Q + P P ++ + +A P++ S + P P G+ +
Sbjct: 1598 SGSSPEVKDKPRAAPRAQSGSDSSPEP---KAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654
Query: 179 LNSGPQ----PGTAPATQHSQAGPATGQAYGPHTYTEPAKPK--KGQQLWNRMKPAPGTG 232
S P+ TA S P T P + + P+ + +L R + A +
Sbjct: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
Query: 233 GLKFNIQKRPFAVTTQSFGSNAEGQHS------------------GFGPQPNPEKVQNHS 274
+ R + S AE S G P P P +Q
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774
Query: 275 GSSARGNLSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTID 334
S R + + R + + R + + R + GS Y
Sbjct: 1775 SRSRR-----------EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYH-- 1821
Query: 335 WSREPL-------PGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGA 387
SR P R + +P R + S P S +R A +R
Sbjct: 1822 -SRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRT 1880
Query: 388 GGAGRARGNSFTKFGNR-------NVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSD 440
R R S T +R +V + + S +S SR RS SR+P RRS S +
Sbjct: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940
Query: 441 SDSSYSGNECHPVGR-----RNPPPKGRGGRG--AHMDRGRGRA------QRGKRHDLAP 487
+ S + PV R R PP R R + + R R R+ +R R +P
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
Query: 488 TKRSRKK 494
R R +
Sbjct: 2001 VTRRRSR 2007
Score = 34.7 bits (78), Expect = 0.36
Identities = 69/326 (21%), Positives = 113/326 (34%), Gaps = 36/326 (11%)
Query: 112 GSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQ--P 169
G+P + G S +Q PQ + P P E S + PP+
Sbjct: 847 GTPPRQGSITS--PQANEQSVTPQRRSCFESSPDP---ELKSRTPSRHSCSGSSPPRVKS 901
Query: 170 SNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQ------QLWN 223
S PP + + +S PQP Q + + P T P++ + + +
Sbjct: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVES 961
Query: 224 RMKPA-PGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSG-FGPQPNPEKVQNHSGSSARGN 281
R+ P +G + + +P QS HSG P P K Q G S G+
Sbjct: 962 RLLPRYSHSGSSSPDTKVKPETPPRQS--------HSGSISPYPK-VKAQTPPGPSLSGS 1012
Query: 282 LSGKPDDWPQDMKEYVERC---FTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSRE 338
S P + +D V+ C + C + + V +L+ S + D +
Sbjct: 1013 KSPCPQEKSKD--SLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSD 1070
Query: 339 PLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSF 398
R+ +ESP + + S P+G S + +P G +
Sbjct: 1071 TSSPEVRQSHSESPSLQ----SKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPM 1126
Query: 399 TKFG---NRNVFMKDNSSSSSTDSRS 421
K G ++ F D+SS + DS S
Sbjct: 1127 LKSGMSPEQSRFQSDSSSYPTVDSNS 1152
Score = 30.0 bits (66), Expect = 8.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 9/89 (10%)
Query: 409 KDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGA 468
+ +SSSSS+ S S SSS S + S SDS+ S + +R P P
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP-------- 2582
Query: 469 HMDRGRGRAQRGKRHDLAPTKRSRKKMAA 497
+ + G+ + P KR R+ ++
Sbjct: 2583 -TPAPKEAVREGRPPEPTPAKRKRRSSSS 2610
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/264 (25%), Positives = 95/264 (35%), Gaps = 58/264 (21%)
Query: 54 AAGGSAKSSSNGPVA--SAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSY 111
A+ G SSS P A S+ ++S E Q QQ Q +Q+ ++ P
Sbjct: 30 ASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLP-- 87
Query: 112 GSPSQYGMAGSYGSATPQQPSAP---------------QHQGTLNQ-------------- 142
P G YG P P P +HQ +Q
Sbjct: 88 --PPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELES 145
Query: 143 ----PPVPG---MDESMSYQAPPQQLPSAQPP---QPSNPPHGAHTLNS-------GPQP 185
PPVP M S SY PPQ PS PP QP PP S P P
Sbjct: 146 PPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTP 205
Query: 186 GTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTG--GLKFNIQKRPF 243
+ ++ SQ+ + Q+Y P + P++P +G + P P + G K +Q+ P
Sbjct: 206 SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPL 265
Query: 244 AVTTQSFGSNAEGQHSGFGPQPNP 267
+S N + P+P+P
Sbjct: 266 ----ESGAKNKSTEQQQAAPEPDP 285
Score = 34.7 bits (78), Expect = 0.36
Identities = 29/89 (32%), Positives = 32/89 (35%), Gaps = 16/89 (17%)
Query: 144 PVPGMDESMSYQAPPQQLP-----SAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGP 198
P PGM S+S PP LP SA PP PP +L+S P P S A P
Sbjct: 574 PPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPP----SLSSTAPPPVMPLPPLSSATP 629
Query: 199 ATG-------QAYGPHTYTEPAKPKKGQQ 220
G Q P P P Q
Sbjct: 630 PPGIPPPGVPQGIPPQLTAAPVPPASSSQ 658
Score = 33.5 bits (75), Expect = 0.80
Identities = 22/92 (23%), Positives = 38/92 (41%), Gaps = 1/92 (1%)
Query: 82 QQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLN 141
+Q++ Q + + + + P + + S+ GM GS P P + G++
Sbjct: 1468 EQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMG-KPPGSIV 1526
Query: 142 QPPVPGMDESMSYQAPPQQLPSAQPPQPSNPP 173
+P P S+ PP +P PP P PP
Sbjct: 1527 RPSAPPARSSVPVTRPPVPIPPPPPPPPLPPP 1558
Score = 32.0 bits (71), Expect = 2.3
Identities = 38/147 (25%), Positives = 55/147 (37%), Gaps = 31/147 (21%)
Query: 81 LQQQQYYQWYQQYN----------YAYPYS-----YYYPMSMYQSYGSPSQ--------- 116
+QQQQ+ YQ++ ++YP+ Y +Q + +Q
Sbjct: 443 MQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNS 502
Query: 117 -YGMAGSY-GSATPQQPSAPQHQGTLNQP--PVPGMDESMSYQAPPQQLPSAQPPQPSNP 172
M Y G+ + P P Q P P P + S+ P LP+ PP P
Sbjct: 503 FQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP 562
Query: 173 PHGAHTL-NSGPQPGTAPATQHSQAGP 198
P +L S P PG P+ S AGP
Sbjct: 563 PVMPPSLPTSVPPPGMPPSL--SSAGP 587
Score = 30.0 bits (66), Expect = 8.9
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 10/68 (14%)
Query: 106 SMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQ 165
S Y + + + G+ + S T PSAP L PPV S PP +P
Sbjct: 1578 SFYGLWDTNDEQGLNSEFKSETAAIPSAP----VLPPPPVH------SSIPPPGPVPMGM 1627
Query: 166 PPQPSNPP 173
PP PP
Sbjct: 1628 PPMSKPPP 1635
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 52.4 bits (124), Expect = 2e-06
Identities = 108/465 (23%), Positives = 163/465 (35%), Gaps = 79/465 (16%)
Query: 56 GGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYY------YPMSMYQ 109
G A ++ V + Q A+++ Q Y + QQ P SY Y S Y
Sbjct: 94 GTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYS 153
Query: 110 ---SYGSPSQYGMAGSYG--SATPQQP--SAPQHQGTLNQPPVPGMDESMSYQAPPQQLP 162
+YG PS YG SYG S+ QQP S P G+ +Q P +S SY Q
Sbjct: 154 QQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQS 209
Query: 163 SAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLW 222
S + PS+ G + SG G P S +GP + G + + G+
Sbjct: 210 SFRQDHPSS--MGVYGQESGGFSG--PGENRSMSGP-DNRGRGRGGFDRGGMSRGGR--- 261
Query: 223 NRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNL 282
G GG+ ++ F + G EG GP +P++ ++S +G
Sbjct: 262 -----GGGRGGMGSAGERGGF---NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 313
Query: 283 SGKPDDWPQDMKEYVERCFTACESEE----------DKDRTEKLLKEVLQARLQDGSAYT 332
D D+ ++ ++C ++ DK+ + + +
Sbjct: 314 DSVTLD---DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAA 370
Query: 333 IDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGR 392
++W ++ V+ + KK + PPR RG P + G G GG G
Sbjct: 371 VEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREG----RGMPPPLRGGPGGPGGPGG 426
Query: 393 ARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGN---- 448
G + G+R F SR S +H R D + + N
Sbjct: 427 PMGRMGGRGGDRGGF----PPRGPRGSRGNPSGGGNVQH-RAGDWQCPNPGCGNQNFAWR 481
Query: 449 -ECHPVGRRNP--------PPKG-----------RGGRGAHMDRG 473
EC+ P PP G RGGRG MDRG
Sbjct: 482 TECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG 526
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 52.0 bits (123), Expect = 2e-06
Identities = 92/386 (23%), Positives = 127/386 (32%), Gaps = 88/386 (22%)
Query: 108 YQSYGSPS-QYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQP 166
Y +GS S + G +GS + Q S+ QH + Q G ES S+ A +
Sbjct: 828 YSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGR------- 880
Query: 167 PQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQA--YGPHTYTEPAKPKKGQQLWNR 224
G H SG PG H Q G +GQ+ YG H G+
Sbjct: 881 --------GRHGSGSGQSPG------HGQRGSGSGQSPSYGRHGSGSGRSSSSGRH---- 922
Query: 225 MKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQH-SGFGPQPNPEKVQNHSGSSAR---- 279
G+G Q F + S S+ QH SG G + E+ + SG S+R
Sbjct: 923 ---GSGSG------QSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH 973
Query: 280 GNLSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREP 339
G+ SG + Q GS SR+
Sbjct: 974 GSSSGSSSSYGQH-----------------------------------GSG-----SRQS 993
Query: 340 LP-GLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARG--N 396
L G +SP R S G G G S RG P G+G + G +
Sbjct: 994 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRG-PYESGSGHSSGLGH 1052
Query: 397 SFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRR 456
++ G + + + SSS + + + S S S SS G H G
Sbjct: 1053 RESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ--HGSGSS 1110
Query: 457 NPPPKGRGGRGAHMDRGRGRAQRGKR 482
GR G G+ G G+ G R
Sbjct: 1111 QSSGYGRQGSGSGQSPGHGQRGSGSR 1136
Score = 48.9 bits (115), Expect = 2e-05
Identities = 107/521 (20%), Positives = 175/521 (33%), Gaps = 69/521 (13%)
Query: 10 STDWSSQYSMVAGAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAKSSSNGPVAS 69
S+ SS Y R++ + + +RQ+ + + +G S+ +G +S
Sbjct: 276 SSGSSSSYGQHGSGSRQS-----LGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSS 330
Query: 70 AQYV-SQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQS----YGSPS-QYGMAGSY 123
Y E+ + Q + Q + YS + S + S +GS S Q +G +
Sbjct: 331 YSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQH 390
Query: 124 GSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQ-QLPSAQPPQPSNPPHG---AHTL 179
GS++ Q S QH+ G S S Q+P Q S PS+ HG +
Sbjct: 391 GSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSS 450
Query: 180 NSGPQ---PGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKF 236
+SGP G + H ++ Y H GQ +G
Sbjct: 451 SSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQH-------GSRSGQSSR 503
Query: 237 NIQKRPFAVTTQSFGSNAEGQH---------SGFGPQPNPEKVQNHSGSSARGNLSGKPD 287
++ A ++ S+G + G SG G P+P + ++ SGS R + S P
Sbjct: 504 GERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGS--RQSSSYGPH 561
Query: 288 DWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAY------TIDWSREPLP 341
+ R + E + L + ++R S Y + S
Sbjct: 562 GYGSG------RSSSRGPYESGSGHSSGLGHQ--ESRSGQSSGYGQHGSSSGHSSTHGQH 613
Query: 342 GLTREPVAESPKKKRWEAASSLHPPRGAGSAT-----RGGGAPSQRGTPGAGGAGRARGN 396
G T + + SS H G+GS+ + G Q + G G+ +
Sbjct: 614 GSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSS 673
Query: 397 SFTKFGNRNVFMKDNS--------------SSSSTDSRSRSSSRSPTRHFRRSDSHSDSD 442
S+ + G+ + + N S S S S S + H H
Sbjct: 674 SYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRS 733
Query: 443 SSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRGKRH 483
S +E H G+ G G+H G GR G H
Sbjct: 734 GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
Score = 48.9 bits (115), Expect = 2e-05
Identities = 105/492 (21%), Positives = 166/492 (33%), Gaps = 80/492 (16%)
Query: 52 SGAAG-GSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMS---- 106
SG G G +SSS+GP S S ++ Y Q+ +S +
Sbjct: 439 SGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRS 498
Query: 107 --------MYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVP--GMDESMSYQA 156
S GS S YG +GS + Q +H Q P P G ES S Q+
Sbjct: 499 GQSSRGERQGSSAGSSSSYGQ---HGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQS 555
Query: 157 PP-------QQLPSAQPPQPSNPPH----GAHTLNSGPQPG-------TAPATQHSQAGP 198
S++ P S H G SG G + ++ H Q G
Sbjct: 556 SSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
Query: 199 ATGQA---------------YGPHTYTEPAKPKKGQQ-LWNRMKPAPGTGGLKFNIQKRP 242
+GQ+ +G H + GQQ + P+ G G F
Sbjct: 616 TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSY 675
Query: 243 FAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEYVERCFT 302
+ S S++ G H Q + ++ SG S+ + G +++ R
Sbjct: 676 GQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQ 735
Query: 303 ACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAAS- 361
+ SE+ + + + Q GS + G SP + R ++S
Sbjct: 736 SSRSEQHGSSSG-----LSSSYGQHGSGS----HQSSGHGRQGSGSGHSPSRVRHGSSSG 786
Query: 362 --SLHPPRGAGSATRGGGAPSQRGTPGAGGAGR---ARGNSFTKFGNRNVFMKDNSSSSS 416
S H G+G++ + G+ A G G+ G +++ G+ + S
Sbjct: 787 HSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGS 846
Query: 417 TDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGR 476
T +S SS + DS S SSY +E + GRG G+ + G
Sbjct: 847 TSGQSSSSGQH--------DSSSGQSSSYGQHES-----ASHHASGRGRHGSGSGQSPGH 893
Query: 477 AQRGKRHDLAPT 488
QRG +P+
Sbjct: 894 GQRGSGSGQSPS 905
Score = 46.2 bits (108), Expect = 1e-04
Identities = 101/486 (20%), Positives = 167/486 (34%), Gaps = 69/486 (14%)
Query: 48 SISKSGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSM 107
S S S GS SSS GP S S + Y Q+ + +S S
Sbjct: 1491 SSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHS-----ST 1545
Query: 108 YQSYGSPS-QYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQ-QLPSAQ 165
+ +GS S Q G +G+++ Q S QH +Q G S S Q+P Q S
Sbjct: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
Query: 166 PPQPSNPPHGA----------HTLNSGPQPG-------TAPATQHSQAGPATGQA--YGP 206
PS HG+ H G G + ++ +SQ G +G + YG
Sbjct: 1606 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1665
Query: 207 HTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQ-- 264
H + + +G++ + + + G + + + QS G +G SG P
Sbjct: 1666 HG-SRSGQSSRGERHGSSSRSSSRYG--------QHGSGSRQSSGHGRQGSGSGQSPSRG 1716
Query: 265 PNPEKVQNHSGSSARGNLSGKPDD-WPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQA 323
+ + + S G+ SG+ P + + F ES A
Sbjct: 1717 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHS----------SA 1766
Query: 324 RLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSAT-----RGGGA 378
Q GS + + + G T + ++ SS H G+GS+ + G
Sbjct: 1767 YSQHGSG-SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
Query: 379 PSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNS---------------SSSSTDSRSRS 423
Q + G G+G +S+ + G+ + + + SSS S +
Sbjct: 1826 SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT 1885
Query: 424 SSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRGKRH 483
S + H + H S E H + G+ G G+ G G+ G
Sbjct: 1886 QHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 1945
Query: 484 DLAPTK 489
+P++
Sbjct: 1946 SPSPSR 1951
Score = 46.2 bits (108), Expect = 1e-04
Identities = 83/384 (21%), Positives = 132/384 (34%), Gaps = 35/384 (9%)
Query: 111 YGSPSQYGMA-GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQP 169
+GS S + + G +GS + S+ +H Q G ES S+Q+ S
Sbjct: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS------SGYTQHG 2358
Query: 170 SNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQ-LWNRMKPA 228
S H + G + G + + + + +YG H GQ + P+
Sbjct: 2359 SGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 2418
Query: 229 PGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNP-EKVQNHS-GSSARGNLSGKP 286
P G R + + QS + G SG+ P E HS G R + SG+
Sbjct: 2419 PSRG--------RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS 2470
Query: 287 DDWPQD------MKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPL 340
+ Q + + T+ +S + + GS+ + + R+
Sbjct: 2471 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2530
Query: 341 PGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAG-GAGRARGNSFT 399
+SP + + S P G + G G S G G+G G G+ +
Sbjct: 2531 GS------GQSPGHGQRGSGSRQSPSYGRHGS--GSGRSSSSGQHGSGLGESSGFGHHES 2582
Query: 400 KFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPP 459
G + + + S S + + SRS R + H S S S H G R
Sbjct: 2583 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS--RGERHGSSSGSSSHYGQHGSGSRQSS 2640
Query: 460 PKGRGGRGAHMDRGRGRAQRGKRH 483
GR G G+ RGR G H
Sbjct: 2641 GHGRQGSGSGQSPSRGRHGSGLGH 2664
Score = 45.4 bits (106), Expect = 2e-04
Identities = 83/384 (21%), Positives = 133/384 (34%), Gaps = 35/384 (9%)
Query: 111 YGSPSQYGMA-GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQP 169
+GS S + + G +GS + S+ +H Q G ES S+Q+ S
Sbjct: 1365 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS------SGCTQHG 1418
Query: 170 SNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQ-LWNRMKPA 228
S H + G + G + + + + +YG H GQ + P+
Sbjct: 1419 SGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1478
Query: 229 PGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNP-EKVQNHS-GSSARGNLSGKP 286
P G R + + QS + G SG+ P E +HS G R + SG+
Sbjct: 1479 PSRG--------RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQS 1530
Query: 287 DDWPQD------MKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPL 340
+ Q + + T+ +S + + GS+ + + R+
Sbjct: 1531 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 1590
Query: 341 PGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAG-GAGRARGNSFT 399
+SP + + S P G + G G S G G+G G G+ +
Sbjct: 1591 GS------GQSPGHGQRGSGSRQSPSYGRHGS--GSGRSSSSGQHGSGLGESSGFGHHES 1642
Query: 400 KFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPP 459
G + + + S S + + SRS R + H S S S H G R
Sbjct: 1643 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS--RGERHGSSSRSSSRYGQHGSGSRQSS 1700
Query: 460 PKGRGGRGAHMDRGRGRAQRGKRH 483
GR G G+ RGR G H
Sbjct: 1701 GHGRQGSGSGQSPSRGRHGSGLGH 1724
Score = 44.7 bits (104), Expect = 3e-04
Identities = 110/532 (20%), Positives = 181/532 (34%), Gaps = 78/532 (14%)
Query: 10 STDWSSQYSMVAGAGRENGMETPMH-----ENPEWEKARQALASISKSGAA---GGSAKS 61
S+ SS Y G+G + H ++P + R S S GS S
Sbjct: 976 SSGSSSSYGQ-HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWS 1034
Query: 62 SSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPS-QYGMA 120
SS GP S S + Y Q+ + +S S + +GS S Q
Sbjct: 1035 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS-----STHGQHGSTSGQSSSC 1089
Query: 121 GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQ-QLPSAQPPQPSNPPHGA--- 176
G +G+++ Q S QH +Q G S S Q+P Q S PS HG+
Sbjct: 1090 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 1149
Query: 177 -------HTLNSGPQPG-------TAPATQHSQAGPATGQA--YGPHTYTEPAKPKKGQQ 220
H G G + ++ +SQ G +G + YG H + + +G++
Sbjct: 1150 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG-SRSGQSSRGER 1208
Query: 221 LWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQ--PNPEKVQNHSGSSA 278
G+ + + + + QS G +G SG P + + + S
Sbjct: 1209 --------HGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQ 1260
Query: 279 RGNLSGKPDD-WPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSR 337
G+ SG+ P + + F ES A Q GS + +
Sbjct: 1261 HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHS----------SAYSQHGSG-SGHFCS 1309
Query: 338 EPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSAT-----RGGGAPSQRGTPGAGGAGR 392
+ G T + ++ SS + RG+GS+ R G Q + G G+G
Sbjct: 1310 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGS 1369
Query: 393 ARGNSFTKFGNRNVFMKDNS---------------SSSSTDSRSRSSSRSPTRHFRRSDS 437
+S+ + G+ + + + SSS S + S + H +
Sbjct: 1370 GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQ 1429
Query: 438 HSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRGKRHDLAPTK 489
H S E H + G+ G G+ G G+ G +P++
Sbjct: 1430 HGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR 1481
Score = 44.7 bits (104), Expect = 3e-04
Identities = 103/492 (20%), Positives = 164/492 (33%), Gaps = 68/492 (13%)
Query: 48 SISKSGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSM 107
S S+ GS +SSS GP S S + + + S S
Sbjct: 1948 SPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSS-----GLGHRESRSGQSSG 2002
Query: 108 YQSYGSPSQYGMA-GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQP 166
Y +GS S + G +GSA+ Q S QH + Q G S S Q+ +
Sbjct: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2062
Query: 167 PQPSNPPHGAHTLNSGPQP-------GTAPATQHSQAGPATGQAYG-PHTYTEPAKPKKG 218
Q +P HG S P G+ ++ Q GP G++ G H + +
Sbjct: 2063 GQ--SPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSY 2120
Query: 219 QQLWNRMKPAPGTG--GLKFNIQKRPFAVTTQSFGSNAEGQH--------------SGFG 262
Q + + G G G + R + S S+ GQH SG G
Sbjct: 2121 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSG 2180
Query: 263 PQPNPEKVQNHSGSSA----RGNLSGKPDD-WPQDMKEYVERCFTACESEEDKDRTEKLL 317
P+ + + SG S+ G+ SG+ P + + F ES
Sbjct: 2181 HSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHS------ 2234
Query: 318 KEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSAT---- 373
A Q GS + + + G T + ++ SS H G+GS+
Sbjct: 2235 ----SAYSQHGSG-SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSY 2289
Query: 374 -RGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNS---------------SSSST 417
+ G Q + G G+G +S+ + G+ + + + SSS
Sbjct: 2290 GQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW 2349
Query: 418 DSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRA 477
S + S + H + H S E H + G+ G G+ G G+
Sbjct: 2350 QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQH 2409
Query: 478 QRGKRHDLAPTK 489
G +P++
Sbjct: 2410 GSGSGQSPSPSR 2421
Score = 43.9 bits (102), Expect = 6e-04
Identities = 103/462 (22%), Positives = 156/462 (33%), Gaps = 63/462 (13%)
Query: 48 SISKSGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSM 107
S S GS +SSS GP S S + Y Q+ + S
Sbjct: 2195 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHF----CSQ 2250
Query: 108 YQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQ-QLPSAQP 166
Q + Q GS+T Q S QH +Q G S S Q+P + + S
Sbjct: 2251 GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 2310
Query: 167 PQPSNPPHGA----------HTLNSGPQPG----------TAPATQHSQAGPATGQAYGP 206
S HG+ H SG G ++ TQH +G +Y
Sbjct: 2311 HSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG-SGSGHSSSYEQ 2369
Query: 207 HTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPN 266
H + + +G++ G+ + + + + QS G G SG P P+
Sbjct: 2370 HG-SRSGQSSRGER--------HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 2420
Query: 267 PEKVQNHSGSSARGNLSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQ 326
+ + SG S+ + G W Y + + R+ + Q
Sbjct: 2421 RGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ-----SSGYGQ 2475
Query: 327 DGSAYTIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRG--- 383
GS+ + S G T + + SS H G+GS+ G G
Sbjct: 2476 HGSS-SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 2534
Query: 384 TPGAG--GAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDS 441
+PG G G+G + S+ + G + S S+ S S + F +S S
Sbjct: 2535 SPGHGQRGSGSRQSPSYGRHG--------SGSGRSSSSGQHGSGLGESSGFGHHESSSGQ 2586
Query: 442 DSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRGKRH 483
SSYS H G + G G H R G++ RG+RH
Sbjct: 2587 SSSYSQ---HGSGSGH-----SSGYGQHGSRS-GQSSRGERH 2619
Score = 43.9 bits (102), Expect = 6e-04
Identities = 106/477 (22%), Positives = 156/477 (32%), Gaps = 73/477 (15%)
Query: 57 GSAKSSSNGPVASAQYVSQA----EASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYG 112
GS SSS+G S S E+S+ Q Y Q ++ Y + S S G
Sbjct: 2321 GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 2380
Query: 113 SP--SQYGMAGSYG---SATPQQPSAPQHQGTLNQPPVP---------GMDESMSYQAPP 158
S G + SYG S + Q QH Q P P G S S
Sbjct: 2381 ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG 2440
Query: 159 QQLPSAQPPQPSNPPH----GAHTLNSGPQPG-------TAPATQHSQAGPATGQAY--G 205
S++ P S H G SG G + ++ H Q G +GQ+ G
Sbjct: 2441 SGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 2500
Query: 206 PHTYTEPAKPKKGQ------QLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFG-------- 251
H + GQ Q + G+G + Q+ + + S+G
Sbjct: 2501 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 2560
Query: 252 SNAEGQH-SGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEYVERCFTACESEEDK 310
S++ GQH SG G ++ SG S+ + G ++ R + E
Sbjct: 2561 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2620
Query: 311 DRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAG 370
+ S Y G +S R + S P RG
Sbjct: 2621 SSSGS------------SSHY----------GQHGSGSRQSSGHGRQGSGSGQSPSRGRH 2658
Query: 371 SATRGGGAPSQRGTPGAG-GAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPT 429
+ G G S G G+G G +RG ++ G+ +VF + S S + + S+ S S
Sbjct: 2659 GS--GLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS-- 2714
Query: 430 RHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRGKRHDLA 486
HF H + S + G G G+ G GR G L+
Sbjct: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLS 2771
Score = 43.5 bits (101), Expect = 8e-04
Identities = 107/485 (22%), Positives = 162/485 (33%), Gaps = 64/485 (13%)
Query: 35 ENPEWEKARQALASISKSGAAG-GSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQY 93
++P + L S G G GS +SSS GP S S + Y Q+
Sbjct: 1711 QSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH 1770
Query: 94 NYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMS 153
+ S Q + Q GS+T Q S QH +Q G S S
Sbjct: 1771 GSGSGHF----CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 1826
Query: 154 YQAPPQ-QLPSAQPPQPSNPPHGA----------HTLNSGPQPG----------TAPATQ 192
Q+P + + S S HG+ H SG G ++ TQ
Sbjct: 1827 GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQ 1886
Query: 193 HSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGS 252
H +G +Y H + + +G+Q G+ + + + + QS G
Sbjct: 1887 HG-SGSGHSSSYEQHG-SRSGQSSRGEQ--------HGSSSGSSSSYGQHGSGSRQSLGH 1936
Query: 253 NAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEYVERCFTACESEEDKDR 312
G SG P P+ + + SG S+ G W Y + + R
Sbjct: 1937 GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESR 1996
Query: 313 TEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSA 372
+ + Q GS+ + S G + + SS H G+GS+
Sbjct: 1997 SGQ-----SSGYGQHGSS-SGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSS 2050
Query: 373 TRGGGAPSQRG---TPGAG--GAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRS 427
G G +PG G G+G + S+ + G + S S+ S
Sbjct: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG--------SGSGRSSSSGQHGPGLG 2102
Query: 428 PTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRGKRHDLAP 487
+ F +S S SSYS H G + G G H R G++ RG+RH +
Sbjct: 2103 ESSGFGHHESSSGQSSSYSQ---HGSGSGH-----SSGYGQHGSRS-GQSSRGERHGSSS 2153
Query: 488 TKRSR 492
SR
Sbjct: 2154 GSSSR 2158
Score = 43.1 bits (100), Expect = 0.001
Identities = 82/384 (21%), Positives = 129/384 (33%), Gaps = 35/384 (9%)
Query: 111 YGSPSQYGMA-GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQP 169
+GS S + + G +GS + S+ +H Q G ES S+Q+ S
Sbjct: 1835 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS------SGYTQHG 1888
Query: 170 SNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQ-LWNRMKPA 228
S H + G + G + + + + +YG H GQ + P+
Sbjct: 1889 SGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1948
Query: 229 PGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNP-EKVQNHS-GSSARGNLSGKP 286
P G R + + QS G SG+ P E HS G R + SG+
Sbjct: 1949 PSRG--------RHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS 2000
Query: 287 DDWPQD------MKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPL 340
+ Q + + + +S + + GS+ + + R+
Sbjct: 2001 SGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2060
Query: 341 PGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAG-GAGRARGNSFT 399
+SP + + S P G + G G S G G G G G+ +
Sbjct: 2061 GS------GQSPGHGQRGSGSRQSPSYGRHGS--GSGRSSSSGQHGPGLGESSGFGHHES 2112
Query: 400 KFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPP 459
G + + + S S + + SRS R + H S S S H G R
Sbjct: 2113 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS--RGERHGSSSGSSSRYGQHGSGSRQSS 2170
Query: 460 PKGRGGRGAHMDRGRGRAQRGKRH 483
GR G G+ RGR G H
Sbjct: 2171 GHGRQGSGSGHSPSRGRHGSGSGH 2194
Score = 42.7 bits (99), Expect = 0.001
Identities = 99/453 (21%), Positives = 156/453 (34%), Gaps = 46/453 (10%)
Query: 50 SKSGAAGGSAKSSSNGPVASAQYVS--QAEASALQQQQYYQWYQQYNYAYPYSYYYPMSM 107
S+ G+A G S S Q S Q ++S+ Q Y Q ++A S
Sbjct: 829 SQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHA---------SG 879
Query: 108 YQSYGSPS-QYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQP 166
+GS S Q G GS + Q PS +H + G S S Q+ S+
Sbjct: 880 RGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSG 939
Query: 167 PQPSNPPHGAHTLNS------GPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQ 220
HG+ + +S G + G + ++ + + +YG H GQ
Sbjct: 940 QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQH 999
Query: 221 -LWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNP-EKVQNHS-GSS 277
+ P+P G + + + S+G G SG+ P E HS G
Sbjct: 1000 GSGSGQSPSPSRG------RHGSGSGQSSSYGPYRSG--SGWSSSRGPYESGSGHSSGLG 1051
Query: 278 ARGNLSGKPDDWPQD------MKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAY 331
R + SG+ + Q + + T+ +S + + GS+
Sbjct: 1052 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 1111
Query: 332 TIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAG-GA 390
+ + R+ +SP + + S P G + G G S G G+G G
Sbjct: 1112 SSGYGRQGSGS------GQSPGHGQRGSGSRQSPSYGRHGS--GSGRSSSSGQHGSGLGE 1163
Query: 391 GRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNEC 450
G+ + G + + + S S + + SRS R + H S S S
Sbjct: 1164 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS--RGERHGSSSGSSSHYGQ 1221
Query: 451 HPVGRRNPPPKGRGGRGAHMDRGRGRAQRGKRH 483
H G R GR G G+ RGR G H
Sbjct: 1222 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGH 1254
Score = 42.0 bits (97), Expect = 0.002
Identities = 120/539 (22%), Positives = 181/539 (33%), Gaps = 97/539 (17%)
Query: 10 STDWSSQYSMVAGAGRENGMETPMH-----ENPEWEKARQALASISKSGAA---GGSAKS 61
S+ SS Y G+G + H ++P + R S S GS S
Sbjct: 1916 SSGSSSSYGQ-HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWS 1974
Query: 62 SSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPS-QYGMA 120
SS GP S S + Y Q+ + +S S + +GS S Q
Sbjct: 1975 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS-----STHGQHGSASGQSSSC 2029
Query: 121 GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQ-QLPSAQPPQPSNPPHGAHTL 179
G +G+++ Q S QH +Q G S S Q+P Q S PS HG+
Sbjct: 2030 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS--- 2086
Query: 180 NSGPQPGTAPATQHSQAGPATGQAYG-PHTYTEPAKPKKGQQLWNRMKPAPGTG--GLKF 236
G+ ++ Q GP G++ G H + + Q + + G G G +
Sbjct: 2087 ------GSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 2140
Query: 237 NIQKRPFAVTTQSFGSNAEGQH--------------SGFGPQPNPEKVQNHSGSSA---- 278
R + S S+ GQH SG G P+ + + SG S+
Sbjct: 2141 GQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQ 2200
Query: 279 RGNLSGKPDD-WPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSR 337
G+ SG+ P + + F ES A Q GS + +
Sbjct: 2201 HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHS----------SAYSQHGSG-SGHFCS 2249
Query: 338 EPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATR--------GGGAPSQRGTPGAG- 388
+ G T + ++ SS H G+GS+ G G RG G+G
Sbjct: 2250 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGS 2309
Query: 389 ---------GAGRARGNSFTKFGN-----------------RNVFMKDNSSSSSTDSRSR 422
G+G +S + G+ + + + S S + S +
Sbjct: 2310 GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQ 2369
Query: 423 SSSRS-PTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRG 480
SRS + R S S S SSY H G R G+ G G+ R + G
Sbjct: 2370 HGSRSGQSSRGERHGSSSGSSSSYGQ---HGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
Score = 38.5 bits (88), Expect = 0.025
Identities = 92/419 (21%), Positives = 151/419 (36%), Gaps = 43/419 (10%)
Query: 48 SISKSGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSM 107
S S S GS SSS GP S S + Y Q+ + +S S
Sbjct: 2431 SSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS-----ST 2485
Query: 108 YQSYGSPS-QYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQ-QLPSAQ 165
+ +GS S Q G +G+++ Q S QH +Q G S S Q+P Q S
Sbjct: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
Query: 166 PPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYG-PHTYTEPAKPKKGQQLWNR 224
PS HG+ G+ ++ Q G G++ G H + + Q +
Sbjct: 2546 RQSPSYGRHGS---------GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 2596
Query: 225 MKPAPGTG--GLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNL 282
+ G G G + R + S S+ GQH G G + + + SG S +
Sbjct: 2597 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQH-GSGSRQSSGHGRQGSG-SGQSPS 2654
Query: 283 SGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSR----- 337
G+ + + + S +L + + + GS ++ +S+
Sbjct: 2655 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS 2714
Query: 338 -----EPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSAT-----RGGGAPSQRGTPGA 387
+ G T + ++ SS + RG+GS+ R G Q + G
Sbjct: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGR 2774
Query: 388 GGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYS 446
G+G + +S+ + G+ S SS S+ S S + + S+ D SS S
Sbjct: 2775 HGSGSGQSSSYGQHGS-------GSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGS 2826
Score = 37.7 bits (86), Expect = 0.042
Identities = 32/125 (25%), Positives = 41/125 (32%), Gaps = 1/125 (0%)
Query: 358 EAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSST 417
E S H G G G G G G+G +G++ N G+ SSS
Sbjct: 181 EQNSDSHQSSGRGQCGSGSGQSPNYGQHGSG-SGQSSSNDTHGSGSGQSSGFSQHKSSSG 239
Query: 418 DSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRA 477
S S S + H H S E H + G+ G G+ G GR
Sbjct: 240 QSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQ 299
Query: 478 QRGKR 482
G R
Sbjct: 300 GSGSR 304
Score = 31.2 bits (69), Expect = 4.0
Identities = 29/131 (22%), Positives = 46/131 (35%), Gaps = 14/131 (10%)
Query: 361 SSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSR 420
SS H G+GS+ + G+ G G+ S G + + K S S + S+
Sbjct: 319 SSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS----GQSSGYSKHGSGSGHSSSQ 374
Query: 421 SRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMD---RGRGRA 477
+ S S + S S + G+ + GRG H + G
Sbjct: 375 GQHGSTS-------GQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHG 427
Query: 478 QRGKRHDLAPT 488
QRG +P+
Sbjct: 428 QRGSGSGQSPS 438
Score = 30.8 bits (68), Expect = 5.2
Identities = 31/131 (23%), Positives = 48/131 (36%), Gaps = 15/131 (11%)
Query: 361 SSLHPPRGAGSATRGGGAP-----------SQRGTPGAGGAGRARGNSFTKFGNRNVFMK 409
SS + G+GS G + SQ G+ +G + S + +R +
Sbjct: 215 SSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHR 274
Query: 410 DNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAH 469
+S SSS+ + S SR H R+ S S H G + G+ G G+
Sbjct: 275 SSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVR----HGSGSGHSSSHGQHGSGSS 330
Query: 470 MDRGRGRAQRG 480
RG + G
Sbjct: 331 YSYSRGHYESG 341
>gi|19923191 minichromosome maintenance complex component 3
associated protein [Homo sapiens]
Length = 1980
Score = 50.8 bits (120), Expect = 5e-06
Identities = 48/203 (23%), Positives = 85/203 (41%), Gaps = 29/203 (14%)
Query: 568 PDPSTVRPVAVLKKSLCMVKCHWKEKQD------YAFACEQMKSIRQDLTVQGIRTEFTV 621
P P +RP+ VL +++ + ++++ Y F + + IR+D+T Q + TV
Sbjct: 686 PLPHELRPLPVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDPLTV 745
Query: 622 EVYETHARIALE---------------KGDHEEFNQCQTQLKSLYAENLPGNV-----GE 661
+ E R + K ++E +C LK +Y + V E
Sbjct: 746 SLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFCASEAE 805
Query: 662 FTAYRILYYIFTKNSGDITTELAYLTRELKADPCVAHALALRTAWALGNYHRFFRLYCHA 721
F Y +L + N GDI E+ ++ V A+ A N+ RFF+L A
Sbjct: 806 FQGYNVLLSL---NKGDILREVQQFHPAVRNSSEVKFAVQAFAALNSNNFVRFFKLVQSA 862
Query: 722 PCMSGYLVDKFADRERKVALKAM 744
++ L+ + + RK AL+A+
Sbjct: 863 SYLNACLLHCYFSQIRKDALRAL 885
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 50.1 bits (118), Expect = 8e-06
Identities = 109/466 (23%), Positives = 159/466 (34%), Gaps = 98/466 (21%)
Query: 74 SQAEASALQQQQYYQWYQQYNYAYP---------------------YSYYYPMSMYQS-- 110
SQ ++S Q Y Q NY+YP YS P S QS
Sbjct: 149 SQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY 208
Query: 111 -----YGSPSQYGMAGSYG--SATPQQP--SAPQHQGTLNQPPVPGMDESMSYQAPPQQL 161
YG PS YG SYG S+ QQP S P G+ +Q P +S SY Q
Sbjct: 209 SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQ 264
Query: 162 PSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQL 221
S + PS+ G + SG G P S +GP + G + + G+
Sbjct: 265 SSFRQDHPSS--MGVYGQESGGFSG--PGENRSMSGP-DNRGRGRGGFDRGGMSRGGR-- 317
Query: 222 WNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGN 281
G GG+ ++ F + G EG GP +P++ ++S +G
Sbjct: 318 ------GGGRGGMGSAGERGGF---NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL 368
Query: 282 LSGKPDDWPQDMKEYVERCFTACESEE----------DKDRTEKLLKEVLQARLQDGSAY 331
D D+ ++ ++C ++ DK+ + + +
Sbjct: 369 NDSVTLD---DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKA 425
Query: 332 TIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAG 391
++W ++ V+ + KK + PPR RG P + G G GG G
Sbjct: 426 AVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREG----RGMPPPLRGGPGGPGGPG 481
Query: 392 RARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGN--- 448
G + G+R F SR S +H R D + + N
Sbjct: 482 GPMGRMGGRGGDRGGF----PPRGPRGSRGNPSGGGNVQH-RAGDWQCPNPGCGNQNFAW 536
Query: 449 --ECHPVGRRNP--------PPKG-----------RGGRGAHMDRG 473
EC+ P PP G RGGRG MDRG
Sbjct: 537 RTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG 582
Score = 38.9 bits (89), Expect = 0.019
Identities = 43/177 (24%), Positives = 61/177 (34%), Gaps = 30/177 (16%)
Query: 67 VASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSA 126
+AS Y + ++A+A Q Y YA Q+YG S G+YG
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYA---------QTTQAYGQQSY----GTYGQP 47
Query: 127 TPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPG 186
T + Q T Q + SY PP + PQ + P + +G
Sbjct: 48 TDVSYTQAQTTATYGQTAY-----ATSYGQPPTGYTTPTAPQAYSQPVQGY--GTGAYDT 100
Query: 187 TAPATQHSQAGPATGQAYGPH----------TYTEPAKPKKGQQLWNRMKPAPGTGG 233
T +QA A AYG T P +P+ G + +P TGG
Sbjct: 101 TTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGG 157
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 48.1 bits (113), Expect = 3e-05
Identities = 53/191 (27%), Positives = 78/191 (40%), Gaps = 27/191 (14%)
Query: 338 EPLPGLTREPVAESPKKKRWEAAS------------SLHPPRGAGSATRGGGAPSQRGTP 385
+P P +T+E P++K + S ++HP + + TR
Sbjct: 511 QPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTR----------- 559
Query: 386 GAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSY 445
+ GRAR N +K +R+ +SSS ST S S SSS S + R S S S S S
Sbjct: 560 -SRSRGRAR-NKTSKSRSRSSSSSSSSSS-STSSSSGSSSSSGSSSSRSSSSSSSSTSGS 616
Query: 446 SGNECHPVGRRNPPPKGRG-GRGAHMDRGRGRAQRGKRHDLAPTKRSRKKMAALECEDPE 504
S + + + R GRG + DR R+ KR D + +RS K D +
Sbjct: 617 SSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTK 676
Query: 505 RELKKQKRAAR 515
K R+ R
Sbjct: 677 GSKDKNSRSDR 687
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 48.1 bits (113), Expect = 3e-05
Identities = 80/285 (28%), Positives = 111/285 (38%), Gaps = 41/285 (14%)
Query: 15 SQYSMVAGAGRENGMETPMHENPEWEKARQ----ALASISKSGAAGGSAKSSSNGPVASA 70
S Y+ G+G E G T + + + ++ +Q AL ++ GS S V+
Sbjct: 478 SHYTESVGSG-EMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIP 536
Query: 71 QYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQ 130
Q +SQ++ S +Q Q YQQ P MS PS + G SA QQ
Sbjct: 537 QSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGI-QPSPVNVVG-VTSALGQQ 594
Query: 131 PSAPQHQGTLNQPPVPGMDESMSYQAPPQQ--LPSAQPPQPSNPPHGAHTLNSGPQPGTA 188
PS +L QP +P S APP Q LP A PPQ +++ PG
Sbjct: 595 PSI----SSLAQPQLP-----YSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHV 645
Query: 189 ------PATQHSQAGP------ATGQ----AYGPHTYTEPAKPKKGQQL--WNRMKPAPG 230
PA+++ Q P ++GQ G T P +G QL PA
Sbjct: 646 KSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQP 705
Query: 231 TGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPN-PEKVQNHS 274
G + + P AV+ GS Q + G Q N P VQ S
Sbjct: 706 AGASVQPVGQAPAAVSAVPTGS----QIANIGQQANIPTAVQQPS 746
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 48.1 bits (113), Expect = 3e-05
Identities = 44/162 (27%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 346 EPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGA-GGAGRARGNSFTKFGNR 404
+P + SP+ + AA++ PP RG +PS R P + G GRA G + + R
Sbjct: 337 KPSSPSPRVRDKAAAAAPTPP------ARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRR 390
Query: 405 NVFMKDNSSSSSTDSRSRSSSR-SPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGR 463
+ SS+S+ R R R +P R RS S + S S P P P
Sbjct: 391 RRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAP--GPGPEPGSE 448
Query: 464 GGRGAHMDRGRGRAQRGKRHDLAPTKRSRKKMAALECEDPER 505
G G H R + R R + +P+ + + E + R
Sbjct: 449 RGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR 490
Score = 40.8 bits (94), Expect = 0.005
Identities = 93/421 (22%), Positives = 147/421 (34%), Gaps = 57/421 (13%)
Query: 59 AKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYG 118
+ SS+ P S+ Y S L + + + + S S +GSP + G
Sbjct: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG 315
Query: 119 MAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHT 178
+G A +P G+ + PP D+ S P+ A P+ P G
Sbjct: 316 GSGQRSGAHGGRP------GSAHSPP----DKPSS--PSPRVRDKAAAAAPTPPARG--- 360
Query: 179 LNSGPQPGTAPATQHSQAGPATGQA--------YGPHTYTEPAKPKKGQQLWNRMKPAPG 230
P P +AP++Q + G A G A + + + P++ + R +PAP
Sbjct: 361 -KESPSPRSAPSSQ-GRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGR--RRPRPAPP 416
Query: 231 TGGLKFNIQKRPFAVTTQSFGS-------NAEGQHSGFG-------PQPNPEKVQNHSGS 276
G + + R + + G+ +E H G G P+ P G+
Sbjct: 417 RGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGA 476
Query: 277 -SARGNLSGK---------PDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQ 326
RG GK P W R +A + R+ K + + +
Sbjct: 477 HGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG 536
Query: 327 DGSAYTIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPG 386
+G A S R + SP +KR + S PR SA R P R +P
Sbjct: 537 EGRA---RHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSA-RKRPIPYYRPSPS 592
Query: 387 AGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYS 446
+ + + S + S SS +RS +RSP+R S S+ SS S
Sbjct: 593 SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSR--TPSPSYHSRSSSES 650
Query: 447 G 447
G
Sbjct: 651 G 651
Score = 38.5 bits (88), Expect = 0.025
Identities = 51/171 (29%), Positives = 67/171 (39%), Gaps = 24/171 (14%)
Query: 359 AASSLHPPRGAGSATRGGGAPSQRGTPGA----GGAG--------RARGNSFTK----FG 402
++ SL R + + G GAP PG+ GG G RAR S + G
Sbjct: 419 SSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG 478
Query: 403 NRN-VFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPK 461
R K +S S RS SSSRSP++ RS S S + P+ R K
Sbjct: 479 RRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSR----DK 534
Query: 462 GRGGRGAHMDRGRGRAQRGKRHDLAPTKRSRKKMAALECEDPERELKKQKR 512
GR H + RA+R R KR R + +E P R +KR
Sbjct: 535 DGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFME---PRRITSARKR 582
Score = 33.1 bits (74), Expect = 1.0
Identities = 43/139 (30%), Positives = 53/139 (38%), Gaps = 32/139 (23%)
Query: 413 SSSSTDSRSRSS----SRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGA 468
SS S+ S S SS SRSP+ R S H D + +G++ G R+P P G G G+
Sbjct: 256 SSGSSHSPSLSSHYSDSRSPS---RLSPKHRD-EGRKTGSQ-RSSGSRSPSPSGGSGWGS 310
Query: 469 HMDRGRGRAQRGKRH-------------DLAPTKRSRKKMAAL---------ECEDPERE 506
G G QR H +P+ R R K AA E P
Sbjct: 311 PQRNG-GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSA 369
Query: 507 LKKQKRAARFQHGHSRRLR 525
Q R R G RR R
Sbjct: 370 PSSQGRGGRAAGGAGRRRR 388
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 47.8 bits (112), Expect = 4e-05
Identities = 109/466 (23%), Positives = 159/466 (34%), Gaps = 99/466 (21%)
Query: 74 SQAEASALQQQQYYQWYQQYNYAYP---------------------YSYYYPMSMYQS-- 110
SQ ++S Q Y Q NY+YP YS P S QS
Sbjct: 149 SQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY 208
Query: 111 -----YGSPSQYGMAGSYG--SATPQQP--SAPQHQGTLNQPPVPGMDESMSYQAPPQQL 161
YG PS YG SYG S+ QQP S P G+ +Q P +S SY Q
Sbjct: 209 SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQ 264
Query: 162 PSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQL 221
S + PS+ G + SG G P S +GP + G + + G+
Sbjct: 265 SSFRQDHPSS--MGVYGQESGGFSG--PGENRSMSGP-DNRGRGRGGFDRGGMSRGGR-- 317
Query: 222 WNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGN 281
G GG+ ++ F + G EG GP +P++ ++S +G
Sbjct: 318 ------GGGRGGMGAG-ERGGF---NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL 367
Query: 282 LSGKPDDWPQDMKEYVERCFTACESEE----------DKDRTEKLLKEVLQARLQDGSAY 331
D D+ ++ ++C ++ DK+ + + +
Sbjct: 368 NDSVTLD---DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKA 424
Query: 332 TIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAG 391
++W ++ V+ + KK + PPR RG P + G G GG G
Sbjct: 425 AVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREG----RGMPPPLRGGPGGPGGPG 480
Query: 392 RARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGN--- 448
G + G+R F SR S +H R D + + N
Sbjct: 481 GPMGRMGGRGGDRGGF----PPRGPRGSRGNPSGGGNVQH-RAGDWQCPNPGCGNQNFAW 535
Query: 449 --ECHPVGRRNP--------PPKG-----------RGGRGAHMDRG 473
EC+ P PP G RGGRG MDRG
Sbjct: 536 RTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG 581
Score = 38.9 bits (89), Expect = 0.019
Identities = 43/177 (24%), Positives = 61/177 (34%), Gaps = 30/177 (16%)
Query: 67 VASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSA 126
+AS Y + ++A+A Q Y YA Q+YG S G+YG
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYA---------QTTQAYGQQSY----GTYGQP 47
Query: 127 TPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPG 186
T + Q T Q + SY PP + PQ + P + +G
Sbjct: 48 TDVSYTQAQTTATYGQTAY-----ATSYGQPPTGYTTPTAPQAYSQPVQGY--GTGAYDT 100
Query: 187 TAPATQHSQAGPATGQAYGPH----------TYTEPAKPKKGQQLWNRMKPAPGTGG 233
T +QA A AYG T P +P+ G + +P TGG
Sbjct: 101 TTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGG 157
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 47.8 bits (112), Expect = 4e-05
Identities = 109/466 (23%), Positives = 159/466 (34%), Gaps = 99/466 (21%)
Query: 74 SQAEASALQQQQYYQWYQQYNYAYP---------------------YSYYYPMSMYQS-- 110
SQ ++S Q Y Q NY+YP YS P S QS
Sbjct: 155 SQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY 214
Query: 111 -----YGSPSQYGMAGSYG--SATPQQP--SAPQHQGTLNQPPVPGMDESMSYQAPPQQL 161
YG PS YG SYG S+ QQP S P G+ +Q P +S SY Q
Sbjct: 215 SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQ 270
Query: 162 PSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQL 221
S + PS+ G + SG G P S +GP + G + + G+
Sbjct: 271 SSFRQDHPSS--MGVYGQESGGFSG--PGENRSMSGP-DNRGRGRGGFDRGGMSRGGR-- 323
Query: 222 WNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGN 281
G GG+ ++ F + G EG GP +P++ ++S +G
Sbjct: 324 ------GGGRGGMGAG-ERGGF---NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL 373
Query: 282 LSGKPDDWPQDMKEYVERCFTACESEE----------DKDRTEKLLKEVLQARLQDGSAY 331
D D+ ++ ++C ++ DK+ + + +
Sbjct: 374 NDSVTLD---DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKA 430
Query: 332 TIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAG 391
++W ++ V+ + KK + PPR RG P + G G GG G
Sbjct: 431 AVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREG----RGMPPPLRGGPGGPGGPG 486
Query: 392 RARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGN--- 448
G + G+R F SR S +H R D + + N
Sbjct: 487 GPMGRMGGRGGDRGGF----PPRGPRGSRGNPSGGGNVQH-RAGDWQCPNPGCGNQNFAW 541
Query: 449 --ECHPVGRRNP--------PPKG-----------RGGRGAHMDRG 473
EC+ P PP G RGGRG MDRG
Sbjct: 542 RTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG 587
Score = 39.7 bits (91), Expect = 0.011
Identities = 46/172 (26%), Positives = 67/172 (38%), Gaps = 14/172 (8%)
Query: 67 VASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSA 126
+AS Y + ++A+A Q Y YA Y S Y +YG P+ + +A
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQS-YGTYGQPTDVSYTQAQTTA 59
Query: 127 TPQQPSAPQHQGTLNQPP-VPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQP 185
T Q + G QPP V G S Y P +QP Q GA+ +
Sbjct: 60 TYGQTAYATSYG---QPPTVEGT--STGYTTPTAPQAYSQPVQGYGT--GAYDTTTATVT 112
Query: 186 GTAPATQHSQAGPATGQAYGPH----TYTEPAKPKKGQQLWNRMKPAPGTGG 233
T A+ +Q+ T AY + T P +P+ G + +P TGG
Sbjct: 113 -TTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGG 163
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 47.8 bits (112), Expect = 4e-05
Identities = 51/184 (27%), Positives = 69/184 (37%), Gaps = 30/184 (16%)
Query: 112 GSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQP-- 169
G P G +G G PQ P P QG + PG + Q PP PP P
Sbjct: 691 GPPGPQGSSGPQGHMGPQGPPGP--QGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRG 748
Query: 170 -SNPPHGAHTLNSGP--QPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMK 226
PPH H + GP Q P +Q GP G P P P++ Q
Sbjct: 749 MQGPPH-PHGIQGGPGSQGIQGPVSQ----GPLMG--LNPRGMQGPPGPRENQ------G 795
Query: 227 PAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQP--NPEKVQNHSGSSARGNLSG 284
PAP + I P + G + G G GPQ P++++ G +G++ G
Sbjct: 796 PAP-----QGMIMGHP---PQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLG 847
Query: 285 KPDD 288
P +
Sbjct: 848 PPQE 851
Score = 46.6 bits (109), Expect = 9e-05
Identities = 88/390 (22%), Positives = 120/390 (30%), Gaps = 87/390 (22%)
Query: 128 PQQPSAPQHQGTL---NQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQ 184
PQ+ P G L + G E Q PP Q PPQ P G+ + PQ
Sbjct: 807 PQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQ 866
Query: 185 PGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFA 244
P Q GP GP PA+ P P G + F QK P
Sbjct: 867 GSLGPPPQGGMQGPP-----GPQGQQNPAR-----------GPHPSQGPIPFQQQKTPLL 910
Query: 245 VTTQSFGSNAEGQHSG---------------------FGPQPNPEK------VQNHSG-- 275
N EGQ +G G P P K +H G
Sbjct: 911 GDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPM 970
Query: 276 SSARGNLSGKPDDWP--------QDMKEYVERCFTACESEEDKDRTEKLLKEV-LQARLQ 326
S R SG P+ P QD + +R + +D R + + RL+
Sbjct: 971 SERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLR 1030
Query: 327 DGSAYTIDWSREPLPGLTREPVAESPKKKRWEAASSLHP-PRGAGSATRGGGAPSQRGTP 385
+ + PL P++++W P P + G G + RG P
Sbjct: 1031 E-----FEGRGGPL-----------PQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPP 1074
Query: 386 GAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTR---------HFRRSD 436
GA R F + F S + R R+P R F +
Sbjct: 1075 GAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEE 1134
Query: 437 SHSDSDSSYSGNECHPVGRRNPPPKGRGGR 466
+ S+ + G + GR P RGGR
Sbjct: 1135 NFDASEEAARGRDLRGRGRGTP----RGGR 1160
Score = 38.5 bits (88), Expect = 0.025
Identities = 39/159 (24%), Positives = 57/159 (35%), Gaps = 20/159 (12%)
Query: 110 SYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQP 169
S G P Q GM G G Q P+ H +Q P+P + + P Q Q
Sbjct: 868 SLGPPPQGGMQGPPGPQGQQNPARGPHP---SQGPIPFQQQKTPLLGDGPRAPFNQEGQS 924
Query: 170 SNPPHGAHTLNSGPQPGTAPATQHSQA-GPATGQAYG-PHTYTEPAKPKKGQQLWNRMKP 227
+ PP L G P Q GP G + G P+ + P ++ +Q
Sbjct: 925 TGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQ------- 977
Query: 228 APGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPN 266
+GG + ++ PF G + G GP P+
Sbjct: 978 ---SGGPEHGPERGPF-----RGGQDCRGPPDRRGPHPD 1008
Score = 32.7 bits (73), Expect = 1.4
Identities = 40/157 (25%), Positives = 50/157 (31%), Gaps = 30/157 (19%)
Query: 142 QPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTL--------NSGPQPGTAPATQH 193
QPP + Q P Q P +Q PQ PH + + GPQ P
Sbjct: 573 QPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQ 632
Query: 194 SQAGPATGQAY----GPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQS 249
Q GP + GP + P P+ Q R + G G+ Q+ P
Sbjct: 633 GQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM----QRHP------- 681
Query: 250 FGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKP 286
G H GPQ P Q SG G P
Sbjct: 682 ------GPHGPLGPQ-GPPGPQGSSGPQGHMGPQGPP 711
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 47.4 bits (111), Expect = 5e-05
Identities = 58/225 (25%), Positives = 82/225 (36%), Gaps = 40/225 (17%)
Query: 90 YQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYG--SATPQQPSAPQHQGTLNQPPVPG 147
+Q+Y Y +Y+ P + + +Q+ A S G S T P +G QPP P
Sbjct: 3303 FQEYRYGDIRTYHPPAQL-----THTQFPAASSVGLPSRTKTAAQGPPPEGEPLQPPQPV 3357
Query: 148 MDESMSYQAPP---------QQLPSAQPPQPSNPPHGAHTLNSGPQ----PGTAPATQHS 194
+ APP Q PS++ PQ S G T P+ P P H+
Sbjct: 3358 QSTQPAQPAPPCPPSQLGQPGQPPSSKMPQVSQEAKGTQTGVEQPRLPAGPANRPPEPHT 3417
Query: 195 QAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNA 254
Q A + GP ++ P MKP K+P V T S S
Sbjct: 3418 QVQRAQAET-GPTSFPSPVSVS--------MKPDLPVSLPTQTAPKQPLFVPTTSGPSTP 3468
Query: 255 EG---QHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEY 296
G H+ F P P + S+ S +P D Q +K+Y
Sbjct: 3469 PGLVLPHTEFQPAPKQD--------SSPHLTSQRPVDMVQLLKKY 3505
Score = 30.4 bits (67), Expect = 6.8
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Query: 343 LTREPVAESPKKKRWEAAS-SLHPPRGAGSATRGGGAPSQRGTPGAGGAG-RARGNSFTK 400
+TRE P++ + S S H + + + + + R T G+G R+R +S
Sbjct: 224 ITREVRGRRPERNYQHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSS--- 280
Query: 401 FGNRNVFMKDNSSSSSTDSRSRSSSRSPTR 430
+ ++ ++SS S+DS S SS SP R
Sbjct: 281 --SDSISSSSSTSSDSSDSSSSSSDDSPAR 308
>gi|21361320 TRK-fused [Homo sapiens]
Length = 400
Score = 47.4 bits (111), Expect = 5e-05
Identities = 51/164 (31%), Positives = 59/164 (35%), Gaps = 20/164 (12%)
Query: 71 QYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQ 130
QY QA A Q Q Q QQY Y S Y P Q YG Q
Sbjct: 246 QYQQQAGYGAQQPQAPPQQPQQYGIQYSAS-------YSQQTGPQQPQQFQGYGQQPTSQ 298
Query: 131 PSAPQHQGTLNQPPVPGMDESMSYQAP--PQQLPSAQPPQPSNPPHGAHTLNSGPQPGTA 188
AP G Q P YQA P Q +AQ QP+N +T+ QPG A
Sbjct: 299 APAPAFSGQPQQLPA---QPPQQYQASNYPAQTYTAQTSQPTN-----YTVAPASQPGMA 350
Query: 189 PATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTG 232
P +Q P G P + P P G + R +P G G
Sbjct: 351 P-SQPGAYQPRPGFTSLPGSTMTP--PPSGPNPYARNRPPFGQG 391
Score = 38.1 bits (87), Expect = 0.033
Identities = 73/341 (21%), Positives = 113/341 (33%), Gaps = 61/341 (17%)
Query: 41 KARQALASISKSGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYS 100
K + L S+ G G S N V + S +++S Q Q A S
Sbjct: 115 KVNRLLDSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVM--------AASMS 166
Query: 101 YYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQ 160
+ P+ + ++G T Q S P P P D S + +
Sbjct: 167 AFDPLKNQDEINK----NVMSAFG-LTDDQVSGP--------PSAPAEDRSGTPDSIASS 213
Query: 161 LPSAQPP--QPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKG 218
+A PP QP PP+ +G G QAG Q P P++
Sbjct: 214 SSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAP--------PQQP 265
Query: 219 QQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSA 278
QQ G++++ A +Q G Q G+G QP + +
Sbjct: 266 QQY-----------GIQYS------ASYSQQTGPQQPQQFQGYGQQP--------TSQAP 300
Query: 279 RGNLSGKPDDWP-QDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSR 337
SG+P P Q ++Y + A + +T + + Q G A + +
Sbjct: 301 APAFSGQPQQLPAQPPQQYQASNYPA---QTYTAQTSQPTNYTVAPASQPGMAPSQPGAY 357
Query: 338 EPLPGLTREPVAE-SPKKKRWEAASSLHPPRGAGSATRGGG 377
+P PG T P + +P + PP G G G G
Sbjct: 358 QPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPG 398
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
sapiens]
Length = 2191
Score = 47.4 bits (111), Expect = 5e-05
Identities = 52/219 (23%), Positives = 85/219 (38%), Gaps = 24/219 (10%)
Query: 74 SQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSA 133
S + AS+L++Q Y QY +A+ + + P + G QP +
Sbjct: 1076 SSSAASSLKKQ-----YIQYLFAFE------CKIERGEEPPPEVFSTGDTKKQPKLQPPS 1124
Query: 134 PQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQH 193
P + G+L P P S S P L +PP P++ PHG T G + T + H
Sbjct: 1125 PANSGSLQGPQTPQSTGSNSMAEVPGDL---KPPTPASTPHGQMTPMQGGRSST--ISVH 1179
Query: 194 SQAGPATGQAYGPHTYTEPAKP-KKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGS 252
+ ++ P P ++G + + M G + + K PF + GS
Sbjct: 1180 DPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVM------GRMPYEPNKDPFGGMRKVPGS 1233
Query: 253 NAEGQHSGFGPQPNPEKVQNHSGSSARGNLS-GKPDDWP 290
+ G P + + + N S S A NL G+ +P
Sbjct: 1234 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFP 1272
Score = 43.5 bits (101), Expect = 8e-04
Identities = 68/271 (25%), Positives = 88/271 (32%), Gaps = 71/271 (26%)
Query: 71 QYVSQAEASALQQ--QQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYG--SA 126
QY Q + QQ Q YY Q + P + Y P Q Y P Q YG S
Sbjct: 538 QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRY-QPQQDMSQEGYGTRSQ 596
Query: 127 TPQQPSAPQHQ-----------------GTLNQPPV------------PGMDESMSYQAP 157
P P P H+ G+++ P G S Q+
Sbjct: 597 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 656
Query: 158 PQQ-------------LPSAQPPQPSNPPHGAHTLNSGP-QPGTAPATQ----------H 193
P Q +P P P P G++ SGP P + P +Q
Sbjct: 657 PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 716
Query: 194 SQAGPATGQAYGPH-------TYTEPAKPKKG-QQLWNRMKPAPGTGGLKFNIQKRPFAV 245
S + PA Q+ P T P + G QQ M P P GG +
Sbjct: 717 SSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQ----MHAGISS 772
Query: 246 TTQSFGSNAEG-QHSGFGPQPNPEKVQNHSG 275
QS S G Q S +GPQ N + +SG
Sbjct: 773 FQQSNSSGTYGPQMSQYGPQGNYSRPPAYSG 803
Score = 41.2 bits (95), Expect = 0.004
Identities = 61/239 (25%), Positives = 85/239 (35%), Gaps = 46/239 (19%)
Query: 57 GSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYN----------YAYPYSYYYPMS 106
G G + + QY SQ QQ+ Y Q+ Y+ Y YPYS
Sbjct: 1323 GPPAKRHEGDMYNMQYSSQ------QQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQG 1376
Query: 107 --MYQSYGSPSQY--GMAGSYGSATPQQ---------PSAPQHQ----GTLNQPPVPGMD 149
Q++G P Q G S S PQQ P Q++ G PP PGM+
Sbjct: 1377 PGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMN 1436
Query: 150 ESMSYQAPPQQL-PSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHT 208
+ P Q++ +Q P + + ++ QP T P Q P+ H
Sbjct: 1437 RTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPN----HI 1492
Query: 209 YTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNP 267
P+ + L NRM P+ +QK V T Q +G PQP P
Sbjct: 1493 SRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPT--------SQVTGPPPQPPP 1543
Score = 36.6 bits (83), Expect = 0.095
Identities = 64/270 (23%), Positives = 88/270 (32%), Gaps = 16/270 (5%)
Query: 22 GAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAKSSSNGP----VASAQYVSQAE 77
G G++ G + +P W A+Q G G + S P V +
Sbjct: 416 GLGKDMGAQYAA-ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMG 474
Query: 78 ASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQ 137
++ Q Q Y +Y P YP+ + + MAG A +
Sbjct: 475 SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQ----GRTPGAMAGMQYPQQQDSGDATWKE 530
Query: 138 GTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAG 197
PP G Y QQ +Q PQP + P A L S Q P SQ G
Sbjct: 531 TFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG 590
Query: 198 PATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAV-TTQSFGSNAEG 256
T ++ P P KP + + L +I P T S +A G
Sbjct: 591 YGT-RSQPP---LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASG 646
Query: 257 QHSGFGPQPNPEKVQNHSGSSARGNLSGKP 286
S G Q NP Q+ A +LS P
Sbjct: 647 STSSQGDQSNP--AQSPFSPHASPHLSSIP 674
Score = 36.2 bits (82), Expect = 0.12
Identities = 61/238 (25%), Positives = 77/238 (32%), Gaps = 35/238 (14%)
Query: 52 SGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAY-----PYSYYYPMS 106
SG GG + + G A A + A A+A Y + Y P M
Sbjct: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMM 321
Query: 107 MYQSYGSPSQYGMAGSYGSATPQQPSAPQHQG------TLNQ---PPVPGMDESMSYQAP 157
M G + A + +A Q A Q+Q TLNQ P P M S P
Sbjct: 322 MGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMM-RSYGGSYP 380
Query: 158 PQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKK 217
PSA PP PS P + G A Q + AG G+ G Y +
Sbjct: 381 EYSSPSAPPPPPSQPQ------SQAAAAGAAAGGQQAAAGMGLGKDMGAQ-YAAASPAWA 433
Query: 218 GQQLWNRMKPAPGTGGLKFN----------IQKRPFAVTTQSFGSNAEGQHSGFGPQP 265
Q + +PGT G + KRP GSN Q P P
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRP---QLYGMGSNPHSQPQQSSPYP 488
>gi|56090139 TRK-fused [Homo sapiens]
Length = 400
Score = 47.4 bits (111), Expect = 5e-05
Identities = 51/164 (31%), Positives = 59/164 (35%), Gaps = 20/164 (12%)
Query: 71 QYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQ 130
QY QA A Q Q Q QQY Y S Y P Q YG Q
Sbjct: 246 QYQQQAGYGAQQPQAPPQQPQQYGIQYSAS-------YSQQTGPQQPQQFQGYGQQPTSQ 298
Query: 131 PSAPQHQGTLNQPPVPGMDESMSYQAP--PQQLPSAQPPQPSNPPHGAHTLNSGPQPGTA 188
AP G Q P YQA P Q +AQ QP+N +T+ QPG A
Sbjct: 299 APAPAFSGQPQQLPA---QPPQQYQASNYPAQTYTAQTSQPTN-----YTVAPASQPGMA 350
Query: 189 PATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTG 232
P +Q P G P + P P G + R +P G G
Sbjct: 351 P-SQPGAYQPRPGFTSLPGSTMTP--PPSGPNPYARNRPPFGQG 391
Score = 38.1 bits (87), Expect = 0.033
Identities = 73/341 (21%), Positives = 113/341 (33%), Gaps = 61/341 (17%)
Query: 41 KARQALASISKSGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYS 100
K + L S+ G G S N V + S +++S Q Q A S
Sbjct: 115 KVNRLLDSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVM--------AASMS 166
Query: 101 YYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQ 160
+ P+ + ++G T Q S P P P D S + +
Sbjct: 167 AFDPLKNQDEINK----NVMSAFG-LTDDQVSGP--------PSAPAEDRSGTPDSIASS 213
Query: 161 LPSAQPP--QPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKG 218
+A PP QP PP+ +G G QAG Q P P++
Sbjct: 214 SSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAP--------PQQP 265
Query: 219 QQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSA 278
QQ G++++ A +Q G Q G+G QP + +
Sbjct: 266 QQY-----------GIQYS------ASYSQQTGPQQPQQFQGYGQQP--------TSQAP 300
Query: 279 RGNLSGKPDDWP-QDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSR 337
SG+P P Q ++Y + A + +T + + Q G A + +
Sbjct: 301 APAFSGQPQQLPAQPPQQYQASNYPA---QTYTAQTSQPTNYTVAPASQPGMAPSQPGAY 357
Query: 338 EPLPGLTREPVAE-SPKKKRWEAASSLHPPRGAGSATRGGG 377
+P PG T P + +P + PP G G G G
Sbjct: 358 QPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPG 398
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
sapiens]
Length = 2231
Score = 47.4 bits (111), Expect = 5e-05
Identities = 52/219 (23%), Positives = 85/219 (38%), Gaps = 24/219 (10%)
Query: 74 SQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSA 133
S + AS+L++Q Y QY +A+ + + P + G QP +
Sbjct: 1116 SSSAASSLKKQ-----YIQYLFAFE------CKIERGEEPPPEVFSTGDTKKQPKLQPPS 1164
Query: 134 PQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQH 193
P + G+L P P S S P L +PP P++ PHG T G + T + H
Sbjct: 1165 PANSGSLQGPQTPQSTGSNSMAEVPGDL---KPPTPASTPHGQMTPMQGGRSST--ISVH 1219
Query: 194 SQAGPATGQAYGPHTYTEPAKP-KKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGS 252
+ ++ P P ++G + + M G + + K PF + GS
Sbjct: 1220 DPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVM------GRMPYEPNKDPFGGMRKVPGS 1273
Query: 253 NAEGQHSGFGPQPNPEKVQNHSGSSARGNLS-GKPDDWP 290
+ G P + + + N S S A NL G+ +P
Sbjct: 1274 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFP 1312
Score = 43.5 bits (101), Expect = 8e-04
Identities = 68/271 (25%), Positives = 88/271 (32%), Gaps = 71/271 (26%)
Query: 71 QYVSQAEASALQQ--QQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYG--SA 126
QY Q + QQ Q YY Q + P + Y P Q Y P Q YG S
Sbjct: 525 QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRY-QPQQDMSQEGYGTRSQ 583
Query: 127 TPQQPSAPQHQ-----------------GTLNQPPV------------PGMDESMSYQAP 157
P P P H+ G+++ P G S Q+
Sbjct: 584 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 643
Query: 158 PQQ-------------LPSAQPPQPSNPPHGAHTLNSGP-QPGTAPATQ----------H 193
P Q +P P P P G++ SGP P + P +Q
Sbjct: 644 PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703
Query: 194 SQAGPATGQAYGPH-------TYTEPAKPKKG-QQLWNRMKPAPGTGGLKFNIQKRPFAV 245
S + PA Q+ P T P + G QQ M P P GG +
Sbjct: 704 SSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQ----MHAGISS 759
Query: 246 TTQSFGSNAEG-QHSGFGPQPNPEKVQNHSG 275
QS S G Q S +GPQ N + +SG
Sbjct: 760 FQQSNSSGTYGPQMSQYGPQGNYSRPPAYSG 790
Score = 41.2 bits (95), Expect = 0.004
Identities = 61/239 (25%), Positives = 85/239 (35%), Gaps = 46/239 (19%)
Query: 57 GSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYN----------YAYPYSYYYPMS 106
G G + + QY SQ QQ+ Y Q+ Y+ Y YPYS
Sbjct: 1363 GPPAKRHEGDMYNMQYSSQ------QQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQG 1416
Query: 107 --MYQSYGSPSQY--GMAGSYGSATPQQ---------PSAPQHQ----GTLNQPPVPGMD 149
Q++G P Q G S S PQQ P Q++ G PP PGM+
Sbjct: 1417 PGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMN 1476
Query: 150 ESMSYQAPPQQL-PSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHT 208
+ P Q++ +Q P + + ++ QP T P Q P+ H
Sbjct: 1477 RTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPN----HI 1532
Query: 209 YTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNP 267
P+ + L NRM P+ +QK V T Q +G PQP P
Sbjct: 1533 SRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPT--------SQVTGPPPQPPP 1583
Score = 38.1 bits (87), Expect = 0.033
Identities = 64/266 (24%), Positives = 88/266 (33%), Gaps = 21/266 (7%)
Query: 22 GAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAKSSSNGPVASAQYVSQAEASAL 81
G G++ G + +P W A+Q G G + S P+ + +
Sbjct: 416 GLGKDMGAQYAA-ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPM---------DPMVM 465
Query: 82 QQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLN 141
++ Q Y + S YP SYG P TP + Q+
Sbjct: 466 KRPQLYGMGSNPHSQPQQSSPYPGG---SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQ-Q 521
Query: 142 QPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATG 201
PP G Y QQ +Q PQP + P A L S Q P SQ G T
Sbjct: 522 MPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGT- 580
Query: 202 QAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAV-TTQSFGSNAEGQHSG 260
++ P P KP + + L +I P T S +A G S
Sbjct: 581 RSQPP---LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS 637
Query: 261 FGPQPNPEKVQNHSGSSARGNLSGKP 286
G Q NP Q+ A +LS P
Sbjct: 638 QGDQSNP--AQSPFSPHASPHLSSIP 661
Score = 36.2 bits (82), Expect = 0.12
Identities = 61/238 (25%), Positives = 77/238 (32%), Gaps = 35/238 (14%)
Query: 52 SGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAY-----PYSYYYPMS 106
SG GG + + G A A + A A+A Y + Y P M
Sbjct: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMM 321
Query: 107 MYQSYGSPSQYGMAGSYGSATPQQPSAPQHQG------TLNQ---PPVPGMDESMSYQAP 157
M G + A + +A Q A Q+Q TLNQ P P M S P
Sbjct: 322 MGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMM-RSYGGSYP 380
Query: 158 PQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKK 217
PSA PP PS P + G A Q + AG G+ G Y +
Sbjct: 381 EYSSPSAPPPPPSQPQ------SQAAAAGAAAGGQQAAAGMGLGKDMGAQ-YAAASPAWA 433
Query: 218 GQQLWNRMKPAPGTGGLKFN----------IQKRPFAVTTQSFGSNAEGQHSGFGPQP 265
Q + +PGT G + KRP GSN Q P P
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRP---QLYGMGSNPHSQPQQSSPYP 488
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
sapiens]
Length = 2178
Score = 47.4 bits (111), Expect = 5e-05
Identities = 52/219 (23%), Positives = 85/219 (38%), Gaps = 24/219 (10%)
Query: 74 SQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSA 133
S + AS+L++Q Y QY +A+ + + P + G QP +
Sbjct: 1063 SSSAASSLKKQ-----YIQYLFAFE------CKIERGEEPPPEVFSTGDTKKQPKLQPPS 1111
Query: 134 PQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQH 193
P + G+L P P S S P L +PP P++ PHG T G + T + H
Sbjct: 1112 PANSGSLQGPQTPQSTGSNSMAEVPGDL---KPPTPASTPHGQMTPMQGGRSST--ISVH 1166
Query: 194 SQAGPATGQAYGPHTYTEPAKP-KKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGS 252
+ ++ P P ++G + + M G + + K PF + GS
Sbjct: 1167 DPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVM------GRMPYEPNKDPFGGMRKVPGS 1220
Query: 253 NAEGQHSGFGPQPNPEKVQNHSGSSARGNLS-GKPDDWP 290
+ G P + + + N S S A NL G+ +P
Sbjct: 1221 SEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFP 1259
Score = 43.5 bits (101), Expect = 8e-04
Identities = 68/271 (25%), Positives = 88/271 (32%), Gaps = 71/271 (26%)
Query: 71 QYVSQAEASALQQ--QQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYG--SA 126
QY Q + QQ Q YY Q + P + Y P Q Y P Q YG S
Sbjct: 525 QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRY-QPQQDMSQEGYGTRSQ 583
Query: 127 TPQQPSAPQHQ-----------------GTLNQPPV------------PGMDESMSYQAP 157
P P P H+ G+++ P G S Q+
Sbjct: 584 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 643
Query: 158 PQQ-------------LPSAQPPQPSNPPHGAHTLNSGP-QPGTAPATQ----------H 193
P Q +P P P P G++ SGP P + P +Q
Sbjct: 644 PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703
Query: 194 SQAGPATGQAYGPH-------TYTEPAKPKKG-QQLWNRMKPAPGTGGLKFNIQKRPFAV 245
S + PA Q+ P T P + G QQ M P P GG +
Sbjct: 704 SSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQ----MHAGISS 759
Query: 246 TTQSFGSNAEG-QHSGFGPQPNPEKVQNHSG 275
QS S G Q S +GPQ N + +SG
Sbjct: 760 FQQSNSSGTYGPQMSQYGPQGNYSRPPAYSG 790
Score = 41.2 bits (95), Expect = 0.004
Identities = 61/239 (25%), Positives = 85/239 (35%), Gaps = 46/239 (19%)
Query: 57 GSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYN----------YAYPYSYYYPMS 106
G G + + QY SQ QQ+ Y Q+ Y+ Y YPYS
Sbjct: 1310 GPPAKRHEGDMYNMQYSSQ------QQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQG 1363
Query: 107 --MYQSYGSPSQY--GMAGSYGSATPQQ---------PSAPQHQ----GTLNQPPVPGMD 149
Q++G P Q G S S PQQ P Q++ G PP PGM+
Sbjct: 1364 PGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMN 1423
Query: 150 ESMSYQAPPQQL-PSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHT 208
+ P Q++ +Q P + + ++ QP T P Q P+ H
Sbjct: 1424 RTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPN----HI 1479
Query: 209 YTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNP 267
P+ + L NRM P+ +QK V T Q +G PQP P
Sbjct: 1480 SRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPT--------SQVTGPPPQPPP 1530
Score = 38.1 bits (87), Expect = 0.033
Identities = 64/266 (24%), Positives = 88/266 (33%), Gaps = 21/266 (7%)
Query: 22 GAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAKSSSNGPVASAQYVSQAEASAL 81
G G++ G + +P W A+Q G G + S P+ + +
Sbjct: 416 GLGKDMGAQYAA-ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPM---------DPMVM 465
Query: 82 QQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLN 141
++ Q Y + S YP SYG P TP + Q+
Sbjct: 466 KRPQLYGMGSNPHSQPQQSSPYPGG---SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQ-Q 521
Query: 142 QPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATG 201
PP G Y QQ +Q PQP + P A L S Q P SQ G T
Sbjct: 522 MPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGT- 580
Query: 202 QAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAV-TTQSFGSNAEGQHSG 260
++ P P KP + + L +I P T S +A G S
Sbjct: 581 RSQPP---LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS 637
Query: 261 FGPQPNPEKVQNHSGSSARGNLSGKP 286
G Q NP Q+ A +LS P
Sbjct: 638 QGDQSNP--AQSPFSPHASPHLSSIP 661
Score = 36.2 bits (82), Expect = 0.12
Identities = 61/238 (25%), Positives = 77/238 (32%), Gaps = 35/238 (14%)
Query: 52 SGAAGGSAKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAY-----PYSYYYPMS 106
SG GG + + G A A + A A+A Y + Y P M
Sbjct: 262 SGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMM 321
Query: 107 MYQSYGSPSQYGMAGSYGSATPQQPSAPQHQG------TLNQ---PPVPGMDESMSYQAP 157
M G + A + +A Q A Q+Q TLNQ P P M S P
Sbjct: 322 MGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMM-RSYGGSYP 380
Query: 158 PQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKK 217
PSA PP PS P + G A Q + AG G+ G Y +
Sbjct: 381 EYSSPSAPPPPPSQPQ------SQAAAAGAAAGGQQAAAGMGLGKDMGAQ-YAAASPAWA 433
Query: 218 GQQLWNRMKPAPGTGGLKFN----------IQKRPFAVTTQSFGSNAEGQHSGFGPQP 265
Q + +PGT G + KRP GSN Q P P
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRP---QLYGMGSNPHSQPQQSSPYP 488
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 47.0 bits (110), Expect = 7e-05
Identities = 53/194 (27%), Positives = 71/194 (36%), Gaps = 20/194 (10%)
Query: 112 GSPSQYGMAGSYGSATPQQPSAPQHQGTLNQ--PPVPGM--------DESMSYQAPPQQL 161
G P Q G P +P P QG PP PG D+S S ++PP +
Sbjct: 99 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGK- 157
Query: 162 PSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQL 221
P PPQ N P G PQ + Q P G+ GP + K + Q
Sbjct: 158 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGD--KSRSSQSP 215
Query: 222 WNRMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQP--NPEKVQNHSGSSAR 279
+ + P GG N + P + G +G + GP P P+ GS ++
Sbjct: 216 PGKPQGPPPQGG---NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQ 272
Query: 280 GNLS--GKPDDWPQ 291
S GKP PQ
Sbjct: 273 SARSPPGKPQGPPQ 286
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/117 (29%), Positives = 42/117 (35%), Gaps = 9/117 (7%)
Query: 104 PMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPS 163
P Q G P G +P P G PP G +S S ++PP + P
Sbjct: 224 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK-PQ 282
Query: 164 AQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQ 220
P Q N P GP P Q QA PA GQ GP + +P + Q
Sbjct: 283 GPPQQEGNNP-------QGPPPPAGGNPQQPQAPPA-GQPQGPPRPPQGGRPSRPPQ 331
Score = 41.2 bits (95), Expect = 0.004
Identities = 42/147 (28%), Positives = 50/147 (34%), Gaps = 30/147 (20%)
Query: 112 GSPSQYGMAGSYGSATPQQPSAPQHQGTLNQ--PPVPGM--------DESMSYQAPP--- 158
G P Q G P +P P QG PP PG D+S S Q+PP
Sbjct: 160 GPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219
Query: 159 ----------QQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHT 208
Q P P +P PP GP P P Q PA G +
Sbjct: 220 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-----QGPPAQGGSKSQSA 274
Query: 209 YTEPAKPK--KGQQLWNRMKPAPGTGG 233
+ P KP+ Q+ N P P GG
Sbjct: 275 RSPPGKPQGPPQQEGNNPQGPPPPAGG 301
Score = 37.7 bits (86), Expect = 0.042
Identities = 40/166 (24%), Positives = 52/166 (31%), Gaps = 21/166 (12%)
Query: 128 PQQPSAPQHQGTLNQ--PPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQP 185
P +P P QG PP PG + Q + P + P +P PP G QP
Sbjct: 54 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP-----QGGNQP 108
Query: 186 GTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAV 245
P GP P P KP+ P G K + P +
Sbjct: 109 QGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQ-----------GPPPQGDK---SRSPRSP 154
Query: 246 TTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQ 291
+ G +G + GP P P K Q + P PQ
Sbjct: 155 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 46.6 bits (109), Expect = 9e-05
Identities = 50/188 (26%), Positives = 75/188 (39%), Gaps = 24/188 (12%)
Query: 59 AKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAY-----PYSYYYPMSMYQSYGS 113
A+S+++ PV++ + Q + QQQQ Q QQ ++ P ++ +P+ S+ +
Sbjct: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHA 527
Query: 114 PSQYGMAGSYGSATPQQPS----APQH------QGTLNQPPVPGMDESMSYQAPPQQLPS 163
Y M+ S GS P P P H Q N PPV S S + Q
Sbjct: 528 -HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSS--STSQGSYP 584
Query: 164 AQPPQPSNPPHGA-HTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLW 222
P PS P GA + P T+ AT + G T + P P G++
Sbjct: 585 CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR-- 642
Query: 223 NRMKPAPG 230
P+PG
Sbjct: 643 ---APSPG 647
Score = 42.4 bits (98), Expect = 0.002
Identities = 107/480 (22%), Positives = 155/480 (32%), Gaps = 84/480 (17%)
Query: 97 YPYSYYYPMSMYQSYGSPSQYGMAGSY--GSATPQQPSA---PQHQGTLNQPPVPGMDES 151
+PYS S S S S A + A P P + P NQPP +
Sbjct: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP-----KY 427
Query: 152 MSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQ--AGPATGQAYGPHTY 209
P Q + S PP P PP+G NS PG P + +Q A P + H
Sbjct: 428 TQPSLPSQAVWSQGPPPP--PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485
Query: 210 TEPAKPKKGQQLWNRMK-------PAPGT------GGLKFNIQKRPFAVTTQSFGS---- 252
+ + ++ QQ + + P PG GG + P+A+ + S GS
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHH--AHPYAM-SPSLGSLRPY 542
Query: 253 ----------NAEGQHSGFGPQ-PNPEKVQNHSGSSARGNL---SGKPDDWPQDMKEYVE 298
+++ +S GP P N S S+++G+ P PQ
Sbjct: 543 PPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFP 602
Query: 299 RCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWE 358
T S L V+ + Y P P R P SP +
Sbjct: 603 PVPTVTTS-------SATLSTVIATVASSPAGYKTASPPGPPPYGKRAP---SPGAYKTA 652
Query: 359 AASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTD 418
P G+ + R G P RGT G G + S T G + S S
Sbjct: 653 TPPGYKP--GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLP 709
Query: 419 SRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPK--------GRGGR-GAH 469
+ + P + + + P +PPPK + R H
Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKH 769
Query: 470 MDRGRGRAQRG--------------KRHDLAPTKRSRKKMAALECEDPERELKKQKRAAR 515
+DRG R KR DL R + A E ++ ERE +++K R
Sbjct: 770 LDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKERER 829
Score = 37.0 bits (84), Expect = 0.072
Identities = 45/185 (24%), Positives = 60/185 (32%), Gaps = 23/185 (12%)
Query: 127 TPQQPSAPQHQGTLNQPPVPGMDESMSYQAPP--------QQLPSAQPPQPSNPPHGAHT 178
+PQ P + Q + P P + + Y AP Q P A PP P P G
Sbjct: 168 SPQPPDSTPRQPEASFEPHPSVTPT-GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG 226
Query: 179 LNSGPQPG-TAPATQHSQAGPATGQAYGPHTY-----------TEPAKPKKGQQLWNRMK 226
+ SGP G S GP G+ + P T P KP +
Sbjct: 227 VLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLP 286
Query: 227 PAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQN-HSGSSARGNLSGK 285
AP P + +NA G G QP P + + H+ G L
Sbjct: 287 SAPPPANFPHVTPNLPPPPALRPL-NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPG 345
Query: 286 PDDWP 290
P+ P
Sbjct: 346 PEKGP 350
Score = 32.3 bits (72), Expect = 1.8
Identities = 31/113 (27%), Positives = 39/113 (34%), Gaps = 22/113 (19%)
Query: 113 SPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNP 172
+P +G+ G+ + P+ P G L P PP P P P P
Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAP------------PPANFPHVTPNLP--P 303
Query: 173 PHGAHTLN----SGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQL 221
P LN S P G P H + A GQ G P P+KG L
Sbjct: 304 PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMG----GLPPGPEKGPTL 352
Score = 30.0 bits (66), Expect = 8.9
Identities = 29/125 (23%), Positives = 50/125 (40%), Gaps = 25/125 (20%)
Query: 146 PGMDESMSYQAPPQQLPSAQPPQPSNP---PHGAHTLNSGPQPGTAPATQH-------SQ 195
PG ++ + P LP A P+ P P+ + + +S ++ ++ SQ
Sbjct: 344 PGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403
Query: 196 AGPATGQAYGPHT----------YTEPAKPKKGQQLWNRMKPAPGTGG---LKFNIQKRP 242
A P+ ++ P T YT+P+ P Q +W++ P P G N P
Sbjct: 404 ALPSYPHSFPPPTSLSVSNQPPKYTQPSLP--SQAVWSQGPPPPPPYGRLLANSNAHPGP 461
Query: 243 FAVTT 247
F +T
Sbjct: 462 FPPST 466
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 46.6 bits (109), Expect = 9e-05
Identities = 50/188 (26%), Positives = 75/188 (39%), Gaps = 24/188 (12%)
Query: 59 AKSSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAY-----PYSYYYPMSMYQSYGS 113
A+S+++ PV++ + Q + QQQQ Q QQ ++ P ++ +P+ S+ +
Sbjct: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHA 527
Query: 114 PSQYGMAGSYGSATPQQPS----APQH------QGTLNQPPVPGMDESMSYQAPPQQLPS 163
Y M+ S GS P P P H Q N PPV S S + Q
Sbjct: 528 -HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSS--STSQGSYP 584
Query: 164 AQPPQPSNPPHGA-HTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLW 222
P PS P GA + P T+ AT + G T + P P G++
Sbjct: 585 CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR-- 642
Query: 223 NRMKPAPG 230
P+PG
Sbjct: 643 ---APSPG 647
Score = 42.4 bits (98), Expect = 0.002
Identities = 107/480 (22%), Positives = 155/480 (32%), Gaps = 84/480 (17%)
Query: 97 YPYSYYYPMSMYQSYGSPSQYGMAGSY--GSATPQQPSA---PQHQGTLNQPPVPGMDES 151
+PYS S S S S A + A P P + P NQPP +
Sbjct: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP-----KY 427
Query: 152 MSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQ--AGPATGQAYGPHTY 209
P Q + S PP P PP+G NS PG P + +Q A P + H
Sbjct: 428 TQPSLPSQAVWSQGPPPP--PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485
Query: 210 TEPAKPKKGQQLWNRMK-------PAPGT------GGLKFNIQKRPFAVTTQSFGS---- 252
+ + ++ QQ + + P PG GG + P+A+ + S GS
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHH--AHPYAM-SPSLGSLRPY 542
Query: 253 ----------NAEGQHSGFGPQ-PNPEKVQNHSGSSARGNL---SGKPDDWPQDMKEYVE 298
+++ +S GP P N S S+++G+ P PQ
Sbjct: 543 PPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFP 602
Query: 299 RCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWE 358
T S L V+ + Y P P R P SP +
Sbjct: 603 PVPTVTTS-------SATLSTVIATVASSPAGYKTASPPGPPPYGKRAP---SPGAYKTA 652
Query: 359 AASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTD 418
P G+ + R G P RGT G G + S T G + S S
Sbjct: 653 TPPGYKP--GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLP 709
Query: 419 SRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPK--------GRGGR-GAH 469
+ + P + + + P +PPPK + R H
Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKH 769
Query: 470 MDRGRGRAQRG--------------KRHDLAPTKRSRKKMAALECEDPERELKKQKRAAR 515
+DRG R KR DL R + A E ++ ERE +++K R
Sbjct: 770 LDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKERER 829
Score = 37.0 bits (84), Expect = 0.072
Identities = 45/185 (24%), Positives = 60/185 (32%), Gaps = 23/185 (12%)
Query: 127 TPQQPSAPQHQGTLNQPPVPGMDESMSYQAPP--------QQLPSAQPPQPSNPPHGAHT 178
+PQ P + Q + P P + + Y AP Q P A PP P P G
Sbjct: 168 SPQPPDSTPRQPEASFEPHPSVTPT-GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG 226
Query: 179 LNSGPQPG-TAPATQHSQAGPATGQAYGPHTY-----------TEPAKPKKGQQLWNRMK 226
+ SGP G S GP G+ + P T P KP +
Sbjct: 227 VLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLP 286
Query: 227 PAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQN-HSGSSARGNLSGK 285
AP P + +NA G G QP P + + H+ G L
Sbjct: 287 SAPPPANFPHVTPNLPPPPALRPL-NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPG 345
Query: 286 PDDWP 290
P+ P
Sbjct: 346 PEKGP 350
Score = 32.3 bits (72), Expect = 1.8
Identities = 31/113 (27%), Positives = 39/113 (34%), Gaps = 22/113 (19%)
Query: 113 SPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNP 172
+P +G+ G+ + P+ P G L P PP P P P P
Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAP------------PPANFPHVTPNLP--P 303
Query: 173 PHGAHTLN----SGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQL 221
P LN S P G P H + A GQ G P P+KG L
Sbjct: 304 PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMG----GLPPGPEKGPTL 352
Score = 30.0 bits (66), Expect = 8.9
Identities = 29/125 (23%), Positives = 50/125 (40%), Gaps = 25/125 (20%)
Query: 146 PGMDESMSYQAPPQQLPSAQPPQPSNP---PHGAHTLNSGPQPGTAPATQH-------SQ 195
PG ++ + P LP A P+ P P+ + + +S ++ ++ SQ
Sbjct: 344 PGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403
Query: 196 AGPATGQAYGPHT----------YTEPAKPKKGQQLWNRMKPAPGTGG---LKFNIQKRP 242
A P+ ++ P T YT+P+ P Q +W++ P P G N P
Sbjct: 404 ALPSYPHSFPPPTSLSVSNQPPKYTQPSLP--SQAVWSQGPPPPPPYGRLLANSNAHPGP 461
Query: 243 FAVTT 247
F +T
Sbjct: 462 FPPST 466
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 46.6 bits (109), Expect = 9e-05
Identities = 49/191 (25%), Positives = 68/191 (35%), Gaps = 9/191 (4%)
Query: 104 PMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPS 163
P Q G P G +P P G PP G ++S S ++PP + P
Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGK-PQ 181
Query: 164 AQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWN 223
PPQ N P G PQ Q P G+ GP + K + +
Sbjct: 182 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD-NKSQSARSPPG 240
Query: 224 RMKPAPGTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQP--NPEKVQNHSGSSARGN 281
+ + P GG N + P + G +G + GP P P+ GS +R +
Sbjct: 241 KPQGPPPQGG---NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS 297
Query: 282 LS--GKPDDWP 290
S GKP P
Sbjct: 298 RSPPGKPQGPP 308
Score = 42.7 bits (99), Expect = 0.001
Identities = 38/141 (26%), Positives = 47/141 (33%), Gaps = 12/141 (8%)
Query: 104 PMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPS 163
P Q G P G +P P G PP G +S S ++PP + P
Sbjct: 247 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK-PQ 305
Query: 164 AQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGP---------HTYTEPAK 214
PPQ N P G PQ Q P G+ GP + P K
Sbjct: 306 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGK 365
Query: 215 PK--KGQQLWNRMKPAPGTGG 233
P+ Q+ N P P GG
Sbjct: 366 PQGPPQQEGNNPQGPPPPAGG 386
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/117 (29%), Positives = 42/117 (35%), Gaps = 9/117 (7%)
Query: 104 PMSMYQSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPS 163
P Q G P G +P P G PP G +S S ++PP + P
Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGK-PQ 367
Query: 164 AQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQ 220
P Q N P GP P Q QA PA GQ GP + +P + Q
Sbjct: 368 GPPQQEGNNP-------QGPPPPAGGNPQQPQAPPA-GQPQGPPRPPQGGRPSRPPQ 416
Score = 39.7 bits (91), Expect = 0.011
Identities = 47/185 (25%), Positives = 59/185 (31%), Gaps = 24/185 (12%)
Query: 112 GSPSQYGMAGSYGSATPQQPSAPQHQGTLNQ--PPVPGMDESMSYQAPPQQLPSAQPPQP 169
G P Q G P +P P QG PP PG + Q + P + P +P
Sbjct: 59 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 118
Query: 170 SNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAP 229
PP G QP P GP P P KP + P
Sbjct: 119 QGPPP-----QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP----------QGPP 163
Query: 230 GTGGLKFNIQKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQN---HSGSSARG-NLSGK 285
G K + P + G +G + GP P P K Q G+ +G GK
Sbjct: 164 PQGDNKSRSSRSP---PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 220
Query: 286 PDDWP 290
P P
Sbjct: 221 PQGPP 225
Score = 32.0 bits (71), Expect = 2.3
Identities = 38/166 (22%), Positives = 58/166 (34%), Gaps = 10/166 (6%)
Query: 129 QQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTA 188
Q+ S G P G ++ +PP + P PPQ N P G PQ
Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGK-PQGPPPQGGNQPQGPPPPPGKPQGPPP 83
Query: 189 PATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQKRPFAVTTQ 248
Q P G+ GP + ++ + + + P GG N + P +
Sbjct: 84 QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP--GKPQGPPPQGG---NQPQGPPPPPGK 138
Query: 249 SFGSNAEGQHSGFGPQP--NPEKVQNHSGSSARGNLS--GKPDDWP 290
G +G + GP P P+ + +R + S GKP P
Sbjct: 139 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP 184
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 45.8 bits (107), Expect = 2e-04
Identities = 85/356 (23%), Positives = 123/356 (34%), Gaps = 81/356 (22%)
Query: 124 GSATPQQPSAP------QHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAH 177
G+ T + PS P G+ PP P + + +A P PPQPS P A
Sbjct: 2351 GNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPA------PPQPSPAPP-AF 2403
Query: 178 TLNSGPQPGT---APATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGL 234
T P+P APAT + A T P T +P K + ++ + PG
Sbjct: 2404 TSCPAPEPFAELPAPATSLAPAPLITM----PATRPKPKKARAAEESGAKGPRRPGEEA- 2458
Query: 235 KFNIQKRPFAVTTQSFGSNAEG----QHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWP 290
+ ++ VT+ E + G G P+ + + S WP
Sbjct: 2459 ELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWP 2518
Query: 291 QDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVA- 349
+ DG D ++EP PGLT E
Sbjct: 2519 ---------------------------------KATDG-----DLAQEPGPGLTFEDSGN 2540
Query: 350 -ESPKKKRWE----------------AASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGR 392
+SP K + E ++SS +GS T G + G G G GR
Sbjct: 2541 PKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
Query: 393 ARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGN 448
+ ++ + +SSSSS+ S S SSS S + S S S S SS S +
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 45.8 bits (107), Expect = 2e-04
Identities = 53/168 (31%), Positives = 67/168 (39%), Gaps = 19/168 (11%)
Query: 336 SREPLPGLTRE-PVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRAR 394
SR P PG + S EAA++ +G T AP Q G P G AR
Sbjct: 315 SRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASAR 374
Query: 395 GNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFR-----RSDSHSDSDSSYSGNE 449
S + +SSS+S S SRSSSRS +R R RS H+ S S S +
Sbjct: 375 RRSSS---------SSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARS-RSRSWSR 424
Query: 450 CHPVGRRNPPPKGRGGR---GAHMDRGRGRAQRGKRHDLAPTKRSRKK 494
RR + RG R G D R +R P +RSR +
Sbjct: 425 SRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSR 472
Score = 40.0 bits (92), Expect = 0.009
Identities = 47/195 (24%), Positives = 76/195 (38%), Gaps = 20/195 (10%)
Query: 349 AESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFM 408
+ S + R + H G+ R +P++RG G R+R +S ++ +
Sbjct: 427 SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL 486
Query: 409 KDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGR----- 463
+ +SSS S S S S SRS R RS SHS S S +P P
Sbjct: 487 RHHSSSRSRSSWSLSPSRS--RSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRP 544
Query: 464 ------GGRGAHMDRGRGRAQRGKRHDLAPTKRSRKKMAALECEDPERELKKQKRAAR-- 515
G + + G+ + L P ++ + +M + R+ K K+AA+
Sbjct: 545 AASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQ----KALNRQFKADKKAAQEK 600
Query: 516 -FQHGHSRRLRLEPL 529
Q H R+ R + L
Sbjct: 601 MIQQEHERQEREDEL 615
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 45.4 bits (106), Expect = 2e-04
Identities = 93/398 (23%), Positives = 139/398 (34%), Gaps = 33/398 (8%)
Query: 109 QSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQ 168
Q S QY G +GS + Q QH Q G ES S Q+ Q S
Sbjct: 1027 QHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSG---S 1083
Query: 169 PSNPPHGAHTLNSGP-------QPGTAPATQHSQAGPATGQA--YGPHTYTEPAKPKKGQ 219
+ +G H NSG +PG+ ++ Q G +GQ+ +G H Q
Sbjct: 1084 SQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQ 1143
Query: 220 QLWNRMKPAPGTGGLKFNI-----QKRPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHS 274
+ + + G G + Q + T SFG + G + + +
Sbjct: 1144 HEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQST 1203
Query: 275 GSSARGNLSGKPDDWPQDMKEYVERCFTACESEEDKD----RTEKLLKEVLQARLQDGSA 330
G G+ SG+ Q + VE T +E T + + Q GS
Sbjct: 1204 GFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSR 1263
Query: 331 YT---IDWSREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRG-TPG 386
T E V+ + A S +P G+ R G QRG T
Sbjct: 1264 VTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTR 1323
Query: 387 AGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYS 446
G +G + T+ G+R + S S +TDS S R + +HS + S +
Sbjct: 1324 HGHSGHGQS---TQTGSRTSGRQRFSHSDATDSEVHSGVSH--RPHSQEQTHSQAGSQHG 1378
Query: 447 GNECHPVGRRNPPPKGRGGRG-AHMDRGRGRA-QRGKR 482
+E V R+ G+ G H G G++ QRG R
Sbjct: 1379 ESE-STVHERHETTYGQTGEATGHGHSGHGQSTQRGSR 1415
Score = 44.3 bits (103), Expect = 5e-04
Identities = 82/378 (21%), Positives = 126/378 (33%), Gaps = 38/378 (10%)
Query: 113 SPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNP 172
S Q G +GS + Q QH Q G ES S Q+ Q S
Sbjct: 725 SSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYG 784
Query: 173 PHGAHTLNSGPQ--PGTAPATQHSQAGPATGQA--YGPHTYTEPAKPKKGQQLWNRMKPA 228
HG+ + Q G++ +T Q G +GQ+ +G H GQ + +
Sbjct: 785 QHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSS 844
Query: 229 PGTGGLKFNIQKRPFAVTTQSFG----SNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSG 284
G G + ++QS G ++ GQ SGFG + +SG G+ SG
Sbjct: 845 YGQHG----------SGSSQSSGYGQHGSSSGQTSGFGQHRSSS--GQYSGFGQHGSGSG 892
Query: 285 KPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLT 344
+ + Q T + E + + GS+ + + + G +
Sbjct: 893 QSSGFGQH--------GTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQH---GSS 941
Query: 345 REPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNR 404
+ + SS G+GS G + G+ + G G+ S
Sbjct: 942 SGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRS----SQS 997
Query: 405 NVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRG 464
N + SS S+ SS T F H S YSG H G G+
Sbjct: 998 NYGQHGSGSSQSSGYGQHGSSSGQTTGF---GQHRSSSGQYSGFGQHGSGSDQSSGFGQH 1054
Query: 465 GRGAHMDRGRGRAQRGKR 482
G G+ G G+ + R
Sbjct: 1055 GTGSGQSSGFGQYESRSR 1072
Score = 39.3 bits (90), Expect = 0.015
Identities = 84/384 (21%), Positives = 127/384 (33%), Gaps = 44/384 (11%)
Query: 109 QSYGSPSQYGMAGSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQ 168
Q S QY G +GS + Q QH Q G ES S+Q+ Q S
Sbjct: 873 QHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQS 932
Query: 169 PSNPPHGA---HTLNSGP-QPGTAPATQHSQAGPATGQA--YGPHTYTEPAKPKKGQ--- 219
HG+ T G + G+ ++ Q G +GQ+ +G H GQ
Sbjct: 933 SGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHES 992
Query: 220 --QLWNRMKPAPGTGGLKFNIQKRPFAVTTQSFGS--NAEGQHSGFGPQPNPEKVQNHSG 275
N + G+ Q + T FG ++ GQ+SGFG + SG
Sbjct: 993 RSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGS--DQSSG 1050
Query: 276 SSARGNLSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDW 335
G SG+ + Q E ++ + GS+ + +
Sbjct: 1051 FGQHGTGSGQSSGFGQ---------------------YESRSRQSSYGQHGSGSSQSSGY 1089
Query: 336 SREPLPGLTREPVAESPKKKRWEAASSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARG 395
+ G + + + SS G+GS G GT + G +
Sbjct: 1090 GQH---GSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEY 1146
Query: 396 NSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGR 455
S G + SS S+ S PT F + S SD+ SS SG G+
Sbjct: 1147 RS----GQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSS-SGQHISDSGQ 1201
Query: 456 RNPPPKGRGGRGAHMDRGRGRAQR 479
+ G G G+G +Q+
Sbjct: 1202 STGFGQYGSGSGQSTGLGQGESQQ 1225
Score = 36.6 bits (83), Expect = 0.095
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 8/107 (7%)
Query: 376 GGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRS 435
G A SQ G G+ GR +G + G+ + + ST + SR++ R + H S
Sbjct: 2127 GQARSQHGESGSAIHGR-QGTIHGQTGDTTRHGQ-SGHGQSTQTGSRTTGRQRSSHSESS 2184
Query: 436 DS--HSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRG 480
DS HS++ ++SG+ G R+ G+ G H +G Q G
Sbjct: 2185 DSEVHSEASPTHSGHTHSQAGSRH----GQSGSSGHGRQGTTHGQTG 2227
Score = 36.2 bits (82), Expect = 0.12
Identities = 89/410 (21%), Positives = 127/410 (30%), Gaps = 60/410 (14%)
Query: 91 QQYNYAYPYSYYYPMSMYQSYGSPS-----QYGMA-------GSYGSATPQQPSAPQHQG 138
+Q +Y S S Y YGS Q+G+ G YGS + Q QH
Sbjct: 539 RQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGS 598
Query: 139 TLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQ--PGTAPATQHSQA 196
Q G ES S Q+ Q S HG+ + Q G++ +T Q
Sbjct: 599 GSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQY 658
Query: 197 GPATGQA--YGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNI-----QKRPFAVTTQS 249
G +GQ+ +G H GQ + G G + Q + T
Sbjct: 659 GSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSG 718
Query: 250 FGSN--AEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEYVERCFTACESE 307
FG + + GQ S FG + SG G+ SG+ + Q + + S
Sbjct: 719 FGQHELSSGQSSSFGQHGSGS--GQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSG 776
Query: 308 EDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAASSLHPPR 367
+ Q GS T + + S
Sbjct: 777 SSQS----------SGYGQHGSRQTSGFGQH---------------------GSGSSQST 805
Query: 368 GAGSATRGGGAPSQRGTPGAG-GAGRARGNSFTKFGNRNVFMKDNSSSSSTDSRSRSSSR 426
G G G G + G G+G G G ++ + + SS S+ SS
Sbjct: 806 GFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSS 865
Query: 427 SPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGR 476
T F H S YSG H G G+ G G+ G G+
Sbjct: 866 GQTSGF---GQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQ 912
Score = 35.0 bits (79), Expect = 0.28
Identities = 39/125 (31%), Positives = 54/125 (43%), Gaps = 9/125 (7%)
Query: 360 ASSLHPPRGAGSATRGGGAPSQRG-TPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTD 418
A S H G+ R G Q G T G +G + T+ G+R + +S S S+D
Sbjct: 2129 ARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQS---TQTGSRTTGRQRSSHSESSD 2185
Query: 419 SRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRA- 477
S S + SPT H + S + S SG+ H GR+ G H G G++
Sbjct: 2186 SEVHSEA-SPT-HSGHTHSQAGSRHGQSGSSGH--GRQGTTHGQTGDTTRHAHYGYGQST 2241
Query: 478 QRGKR 482
QRG R
Sbjct: 2242 QRGSR 2246
>gi|8923842 forkhead box J2 [Homo sapiens]
Length = 574
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/213 (26%), Positives = 83/213 (38%), Gaps = 49/213 (23%)
Query: 20 VAGAGRENGMETPMHENPEWE-KARQALASISKSG--------AAGGSAKSSSNGP--VA 68
VAG+G + P NP+ ++ ++AS S+ AAG S + S+ GP +
Sbjct: 177 VAGSGEAS---LPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLY 233
Query: 69 SAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGSATP 128
+ + + S + +Q ++++ Y SM + S SQ+G + G P
Sbjct: 234 NTNHDFKFSYSEIN-------FQDLSWSFRNLY---KSMLEKSSSSSQHGFSSLLGDIPP 283
Query: 129 ---------QQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTL 179
QQP PQ Q QPP P PPQQ +QP Q P G +
Sbjct: 284 SNNYYMYQQQQPPPPQQQQQQQQPPQP----------PPQQ---SQPQQQQAPAQGPSAV 330
Query: 180 NSGPQPGTAPATQHSQAGPATGQAYGPHTYTEP 212
P P P+T P G+ G Y P
Sbjct: 331 GGAP-PLHTPST--DGCTPPGGKQAGAEGYGPP 360
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 45.4 bits (106), Expect = 2e-04
Identities = 49/153 (32%), Positives = 54/153 (35%), Gaps = 20/153 (13%)
Query: 98 PYSYYYPMSMYQSYGSPSQYGM--------AGSYGSATPQQ-PSA--PQHQGTL--NQPP 144
P SY MS SY S Y SYG+ P P A P H N PP
Sbjct: 425 PSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPP 484
Query: 145 VPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPATQHSQAGPATGQAY 204
P S+ PP +P P P PP + N P P P T P G
Sbjct: 485 PPVPPPPASF--PPPAIPPPTPGYPPPPP--TYNPNFPPPPPRLPPTHAVPPHPPPGLGL 540
Query: 205 GPHTYTEPAKPKKGQQLWNRMKPAPG---TGGL 234
P +Y PA P GQ P PG GGL
Sbjct: 541 PPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGL 573
Score = 38.9 bits (89), Expect = 0.019
Identities = 38/154 (24%), Positives = 52/154 (33%), Gaps = 6/154 (3%)
Query: 66 PVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMAGSYGS 125
P S+ + S+ + YQ Q SY ++ +YG P+
Sbjct: 423 PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYG---ALPPAYGPPAHLPYHPHVYP 479
Query: 126 ATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQL-PSAQPPQPSNPPHGAHTLNSGPQ 184
P P P + P +P + Y PP P+ PP P PP A + P
Sbjct: 480 PNPPPPPVPPPPASFPPPAIP--PPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPG 537
Query: 185 PGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKG 218
G PA+ A P GQ P P P G
Sbjct: 538 LGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVG 571
Score = 33.5 bits (75), Expect = 0.80
Identities = 36/145 (24%), Positives = 49/145 (33%), Gaps = 18/145 (12%)
Query: 86 YYQWYQQYNYAYPYSYYYPMSMYQS-------YGSPSQYGMAGSYGSATPQQPSAPQHQG 138
Y Q QQ + P+ P S+ + PSQ PQQP+ Q Q
Sbjct: 258 YSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPA--QQQQ 315
Query: 139 TLNQPPVPGMDESMSYQ-------APPQQLPSAQPPQPSNPPHGAHTLNSGPQPGTAPAT 191
QP P S Q +P ++ +A+PP P P T + P P
Sbjct: 316 PAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPK--IETTHPPLPPAHPPPD 373
Query: 192 QHSQAGPATGQAYGPHTYTEPAKPK 216
+ A G+A P PK
Sbjct: 374 RKPPLAAALGEAEPPGPVDATDLPK 398
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,695,227
Number of Sequences: 37866
Number of extensions: 2076854
Number of successful extensions: 17775
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 206
Number of HSP's successfully gapped in prelim test: 889
Number of HSP's that attempted gapping in prelim test: 11758
Number of HSP's gapped (non-prelim): 5077
length of query: 800
length of database: 18,247,518
effective HSP length: 110
effective length of query: 690
effective length of database: 14,082,258
effective search space: 9716758020
effective search space used: 9716758020
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.