Guide to the Human Genome
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Search of human proteins with 24308065

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24308065 netrin 5 [Homo sapiens]
         (489 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24308065 netrin 5 [Homo sapiens]                                  1070   0.0  
gi|148613884 netrin 1 [Homo sapiens]                                  387   e-108
gi|5453810 netrin 3 [Homo sapiens]                                    377   e-104
gi|119703755 laminin, beta 2 precursor [Homo sapiens]                 175   7e-44
gi|110611156 laminin, gamma 3 precursor [Homo sapiens]                164   2e-40
gi|143770880 laminin, beta 4 [Homo sapiens]                           163   4e-40
gi|93204871 netrin 4 [Homo sapiens]                                   161   1e-39
gi|62868217 laminin, beta 3 precursor [Homo sapiens]                  156   4e-38
gi|62868215 laminin, beta 3 precursor [Homo sapiens]                  156   4e-38
gi|189083719 laminin, beta 3 precursor [Homo sapiens]                 156   4e-38
gi|145309326 laminin, gamma 1 precursor [Homo sapiens]                150   3e-36
gi|167614504 laminin, beta 1 precursor [Homo sapiens]                 149   7e-36
gi|219842266 usherin isoform B [Homo sapiens]                         144   2e-34
gi|219842259 usherin isoform A [Homo sapiens]                         144   2e-34
gi|21264602 laminin alpha 5 [Homo sapiens]                            142   5e-34
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]          125   7e-29
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]         125   7e-29
gi|164414431 netrin G1 isoform 1 [Homo sapiens]                       122   6e-28
gi|38788416 laminin, alpha 1 precursor [Homo sapiens]                 122   1e-27
gi|190014607 netrin G2 [Homo sapiens]                                 115   1e-25
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s...   114   2e-25
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa...   114   2e-25
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             99   7e-21
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]          87   3e-17
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]           87   3e-17
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]       83   6e-16
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]       83   6e-16
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       79   9e-15
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]       79   9e-15
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       79   9e-15

>gi|24308065 netrin 5 [Homo sapiens]
          Length = 489

 Score = 1070 bits (2768), Expect = 0.0
 Identities = 489/489 (100%), Positives = 489/489 (100%)

Query: 1   MPVTFALLLLLGQATADPCYDPQGRPQFCLPPVTQLAAVAASCPQACALSPGNHLGARET 60
           MPVTFALLLLLGQATADPCYDPQGRPQFCLPPVTQLAAVAASCPQACALSPGNHLGARET
Sbjct: 1   MPVTFALLLLLGQATADPCYDPQGRPQFCLPPVTQLAAVAASCPQACALSPGNHLGARET 60

Query: 61  CNGSLTLALGGPFLLTSVSLRFCTPGPPALILSAAWASGGPWRLLWHRPAWPGALGGPER 120
           CNGSLTLALGGPFLLTSVSLRFCTPGPPALILSAAWASGGPWRLLWHRPAWPGALGGPER
Sbjct: 61  CNGSLTLALGGPFLLTSVSLRFCTPGPPALILSAAWASGGPWRLLWHRPAWPGALGGPER 120

Query: 121 VTFHSTPGPKATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRHH 180
           VTFHSTPGPKATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRHH
Sbjct: 121 VTFHSTPGPKATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRHH 180

Query: 181 TTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCE 240
           TTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCE
Sbjct: 181 TTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCE 240

Query: 241 RCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGV 300
           RCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGV
Sbjct: 241 RCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGV 300

Query: 301 TGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSL 360
           TGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSL
Sbjct: 301 TGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSL 360

Query: 361 RRYCQQDHVLRAQVLASEAAGPAWQRLAVRVLAVYKQRAQPVRRGDQDAWVPRADLTCGC 420
           RRYCQQDHVLRAQVLASEAAGPAWQRLAVRVLAVYKQRAQPVRRGDQDAWVPRADLTCGC
Sbjct: 361 RRYCQQDHVLRAQVLASEAAGPAWQRLAVRVLAVYKQRAQPVRRGDQDAWVPRADLTCGC 420

Query: 421 LRLQPGTDYLLLGSAVGDPDPTRLILDRHGLALPWRPRWARPLKRLQQEERAGGCRGVRA 480
           LRLQPGTDYLLLGSAVGDPDPTRLILDRHGLALPWRPRWARPLKRLQQEERAGGCRGVRA
Sbjct: 421 LRLQPGTDYLLLGSAVGDPDPTRLILDRHGLALPWRPRWARPLKRLQQEERAGGCRGVRA 480

Query: 481 PTPSPRPEH 489
           PTPSPRPEH
Sbjct: 481 PTPSPRPEH 489


>gi|148613884 netrin 1 [Homo sapiens]
          Length = 604

 Score =  387 bits (995), Expect = e-108
 Identities = 213/578 (36%), Positives = 300/578 (51%), Gaps = 111/578 (19%)

Query: 7   LLLLLGQATA-DPCYDPQGRPQFCLPPVTQLA-----AVAASC--PQA--CALSPGNH-- 54
           L +  GQA   DPC D  G P+ C+P     A      V+++C  P A  C +S      
Sbjct: 28  LSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVSERGEER 87

Query: 55  LGARETCNGS------------------------------------LTLALGGPFLLTSV 78
           L +   CN S                                    LTL+LG  F +T V
Sbjct: 88  LRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYV 147

Query: 79  SLRFCTPGPPALILSAAWASGGPW----------RLLWHRP------------------- 109
           SL+FC+P P ++ +  +   G  W          R +++RP                   
Sbjct: 148 SLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSH 207

Query: 110 -----------AWPGALGGPERVTFHSTPGPKATVAASHLRVEFG--------------- 143
                      A+    G P    F ++P  +  V A+ +RV F                
Sbjct: 208 TDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSEL 267

Query: 144 --GQAGLAAAGLR--GRCQCHGHAARCAA-RARPPRCHCRHHTTGPGCESCRPSHRDWPW 198
                  A + L+  GRC+C+GHAARC   R     C CRH+T GP C+ C+P H D PW
Sbjct: 268 ARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPW 327

Query: 199 RPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGF 258
           + AT R  + C+ C+CN HARRCRFN EL++LSG +SGGVC  CRH+TAGRHCHYC+ G+
Sbjct: 328 QRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387

Query: 259 WRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSP 318
           +RD  +PI  R+AC+AC CHP+GA G TCNQT+GQC CK GVTG+TCNRC  GYQQSRSP
Sbjct: 388 YRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSP 447

Query: 319 RMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSLRRYCQQDHVLRAQVLASE 378
             PC +IP A  T  T   +      C +YC  S  ++ +++++YC++D+ ++  +L ++
Sbjct: 448 IAPCIKIPVAPPT--TAASSVEEPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKAD 505

Query: 379 AAGPAWQRLAVRVLAVYKQRAQPVRRGDQDAWVPRADLTCGCLRLQPGTDYLLLGSAVGD 438
            AG  W +  V +++VYKQ    +RRGDQ  W+   D+ C C +++P   YLLLG+A   
Sbjct: 506 KAGD-WWKFTVNIISVYKQGTSRIRRGDQSLWIRSRDIACKCPKIKPLKKYLLLGNAEDS 564

Query: 439 PDPTRLILDRHGLALPWRPRWARPLKRLQQEERAGGCR 476
           PD + ++ D+  L + WR  WAR L++ QQ E+ G C+
Sbjct: 565 PDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCK 602


>gi|5453810 netrin 3 [Homo sapiens]
          Length = 580

 Score =  377 bits (968), Expect = e-104
 Identities = 229/566 (40%), Positives = 283/566 (50%), Gaps = 99/566 (17%)

Query: 5   FALLLLLGQATADPCYDPQGRPQFCLPPVTQLA-----------------AVAASCPQ-- 45
           FA L     A ADPC+D  G P+ C+P +   A                 A  AS P+  
Sbjct: 16  FAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCGRPATRACDASDPRRA 75

Query: 46  ---ACALSPGNHLGA---------RETCNGSLTLALGGPFLLTSVSLRFCTPGPPALILS 93
              A   SPG              R   N +LT+ LG  F L  VSLRFC+  P ++ L 
Sbjct: 76  HSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVALL 135

Query: 94  AAWASGGPWRLLWH-------------RPAWPGALGGPERVTF----------------- 123
            +   G  W  L                PA   A  GPE + F                 
Sbjct: 136 KSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPLAQPDGSGLLAFSM 195

Query: 124 ----------HSTPGPKATVAASHLRVEFGGQA--------------GLAAAGLR--GRC 157
                      S+P  +  V A+ +RV     +                AA  L+  GRC
Sbjct: 196 QDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRC 255

Query: 158 QCHGHAARCAARARPPR-CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
           +C+GHA+RC    +    C CRH T GP C  C+P + D PW+ AT R  H CL CSCN 
Sbjct: 256 KCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNG 315

Query: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276
           HARRCRFN EL+RLSG RSGGVC  CRH+TAGRHCHYC+ GF+RDP + +  RRACRAC 
Sbjct: 316 HARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375

Query: 277 CHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTP 336
           CHP+GA G TCNQT+GQC CK GVTGLTCNRC PG+QQSRSP  PC + P    T  ++P
Sbjct: 376 CHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSP 435

Query: 337 GAYSSDPQ-CQNYCNMSDTRVHMSLRRYCQQDHVLRAQVLASEAAGPAWQRLAVRVLAVY 395
                 PQ C ++C  +     +SL+++C++D+ ++  V A   A  AW R  V VLAV+
Sbjct: 436 ----VQPQDCDSHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAWTRFPVAVLAVF 491

Query: 396 KQRAQPVRRGDQDAWVPRADLTCGCLRLQPGTDYLLLGSAVG------DPDPTRLILDRH 449
           +   +  RRG    WVP  D  CGC RL PG  YLLLG   G            LI  R 
Sbjct: 492 RSGEERARRGSSALWVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAGGRGPGLIAARG 551

Query: 450 GLALPWRPRWARPLKRLQQEERAGGC 475
            L LPWR  W R L+RLQ+ ER G C
Sbjct: 552 SLVLPWRDAWTRRLRRLQRRERRGRC 577


>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
          Length = 1798

 Score =  175 bits (444), Expect = 7e-44
 Identities = 86/217 (39%), Positives = 115/217 (52%), Gaps = 22/217 (10%)

Query: 153 LRGRCQCHGHAARCAARARPPR---------CHCRHHTTGPGCESCRPSHRDWPWRPATP 203
           +RG C C+GHA+ CA     P          C C+H+T G  CE C+  +RD PWRPA  
Sbjct: 279 VRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338

Query: 204 RHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPS 263
            H H C  C C+ H   C F+  ++  SG  SGGVC+ C+H+TAGRHC  C+P F+RDP+
Sbjct: 339 GHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPT 398

Query: 264 QPIFSRRACRACQCHPIGA-TGGTCNQ--------TSGQCTCKLGVTGLTCNRCGPG-YQ 313
           + +     CR+C C P+G+  GG C+          SGQC CK  V G  C +C  G + 
Sbjct: 399 KDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFG 458

Query: 314 QSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQN-YC 349
            S S R+ C+R         T PG+   DP   + YC
Sbjct: 459 LSISDRLGCRRC--QCNARGTVPGSTPCDPNSGSCYC 493



 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 49/153 (32%), Positives = 65/153 (42%), Gaps = 38/153 (24%)

Query: 175  CHCRHHTTGPGCESCRPSHRDWPWRPA-------TPRHPHPCLPCSCNQHARRCRFNSEL 227
            CHCR   TG  CE+C P H   P RP           +  P  P +C+ H          
Sbjct: 954  CHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHT--------- 1004

Query: 228  FRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT- 286
                     G C RC HHT G HC +C+PGF         +R++C  C C+ +G      
Sbjct: 1005 ---------GQCLRCLHHTEGPHCAHCKPGFHGQA-----ARQSCHRCTCNLLGTNPQQC 1050

Query: 287  -------CNQTSGQCTCKLGVTGLTCNRCGPGY 312
                   C+ +SGQC C   V G +C+RC P +
Sbjct: 1051 PSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNF 1083



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 49/156 (31%), Positives = 63/156 (40%), Gaps = 17/156 (10%)

Query: 157  CQCHGHAARCAARARPPRC----HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC 212
            C+C G+       A  P       C HHT GP C  C+P       R +       C  C
Sbjct: 986  CECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQS-------CHRC 1038

Query: 213  SCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRAC 272
            +CN      +      +     S G C  C  +  G  C  C P FW      + S   C
Sbjct: 1039 TCNLLGTNPQQCPSPDQCHCDPSSGQCP-CLPNVQGPSCDRCAPNFWN-----LTSGHGC 1092

Query: 273  RACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRC 308
            + C CHP  A G TCN+ +GQC C+ G  G TC+ C
Sbjct: 1093 QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSEC 1128



 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 58/179 (32%), Positives = 70/179 (39%), Gaps = 35/179 (19%)

Query: 144 GQAGLAAAGLRGRCQC-HGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPAT 202
           G  G    G +  CQC H  A          +C CR    G  C+ C+     +P     
Sbjct: 819 GYYGFGPTGCQA-CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP----- 872

Query: 203 PRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDP 262
                 C PC CN HA  C  ++           G C  CR HT G HC  C  GF  DP
Sbjct: 873 -----SCRPCVCNGHADECNTHT-----------GACLGCRDHTGGEHCERCIAGFHGDP 916

Query: 263 SQPIFSRRACRACQCHPIG-------ATGGTCNQTSGQ--CTCKLGVTGLTCNRCGPGY 312
             P   +  CR C C P G       AT    ++ S Q  C C+ G TGL C  C PG+
Sbjct: 917 RLPYGGQ--CRPCPC-PEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 58/208 (27%), Positives = 80/208 (38%), Gaps = 38/208 (18%)

Query: 124  HSTPGPKATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRH---- 179
            H T GP      +H +  F GQA   +     RC C+           P +CHC      
Sbjct: 1012 HHTEGPHC----AHCKPGFHGQAARQSCH---RCTCNLLGTNPQQCPSPDQCHCDPSSGQ 1064

Query: 180  -----HTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
                 +  GP C+ C P+     W   +    H C PC+C+    R    +E        
Sbjct: 1065 CPCLPNVQGPSCDRCAPNF----WNLTSG---HGCQPCACHPSRARGPTCNEFT------ 1111

Query: 235  SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
              G C  CR    GR C  CQ   W DP         C AC C   G     C++ +G C
Sbjct: 1112 --GQCH-CRAGFGGRTCSECQELHWGDPGLQ------CHACDCDSRGIDTPQCHRFTGHC 1162

Query: 295  TCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
            +C+ GV+G+ C++C  G+        PC
Sbjct: 1163 SCRPGVSGVRCDQCARGFSGIFPACHPC 1190



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 43/113 (38%), Positives = 51/113 (45%), Gaps = 16/113 (14%)

Query: 210 LPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSR 269
           LPC CN        +SE         GG C  C+    GR C  C PG++       F  
Sbjct: 781 LPCQCNPQGS---LSSEC-----NPHGGQC-LCKPGVVGRRCDLCAPGYYG------FGP 825

Query: 270 RACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
             C+ACQC   GA    C +TSGQC C+ G  GL C+RC  G     S R PC
Sbjct: 826 TGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCR-PC 877



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 55/223 (24%), Positives = 76/223 (34%), Gaps = 75/223 (33%)

Query: 156 RCQCHGHAARC---------AARARPPRCH-CRHHTTGPGCESCRPSHRDWPWRPATPRH 205
           +C+CHGH   C         +       C  C+H+T G  CE CRP     P +    R 
Sbjct: 346 KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDL--RD 403

Query: 206 PHPCLPCSCN----QHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRD 261
           P  C  C C+    Q   RC  + +    + G   G C RC+ H  G  C  C+ GF+  
Sbjct: 404 PAVCRSCDCDPMGSQDGGRCDSHDDP---ALGLVSGQC-RCKEHVVGTRCQQCRDGFF-- 457

Query: 262 PSQPIFSRRACRACQCHPIGATGGT----------------------------------- 286
               I  R  CR CQC+  G   G+                                   
Sbjct: 458 -GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDL 516

Query: 287 -----------------CNQTSGQCTCKLGVTGLTCNRCGPGY 312
                            C++ +GQC C+  + G  C +  PGY
Sbjct: 517 LGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGY 559



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 32/114 (28%), Positives = 41/114 (35%), Gaps = 30/114 (26%)

Query: 156 RCQCHGHAARCAARARPPR---CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC 212
           RCQC+       +    P    C+C+   TG GC+ C P H    W          C PC
Sbjct: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGH----W--GLSHDLLGCRPC 522

Query: 213 SCNQHARRCRFNSELFRLSGGRSGGVCER------CRHHTAGRHCHYCQPGFWR 260
            C+                GG     C+       CR H  GR C   QPG++R
Sbjct: 523 DCDV---------------GGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561


>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
          Length = 1575

 Score =  164 bits (415), Expect = 2e-40
 Identities = 131/485 (27%), Positives = 174/485 (35%), Gaps = 149/485 (30%)

Query: 6   ALLLLLGQATADP---------CYDPQGRPQFCLP------------------------- 31
           A  LLLG A   P         CYD  GRPQ CLP                         
Sbjct: 3   AAALLLGLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPEDFC 62

Query: 32  PVTQLAAVAASCPQACALSPGNH------------------------LGARETCNGSLTL 67
           P    A   A C +  A  P  H                         G +   + ++TL
Sbjct: 63  PHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITL 122

Query: 68  ALGGPFLLTSVSLRFCTPGPPALILSAAWASGGPW----------RLLWHRP-------- 109
            LG  + +T V L+F T  P +  +     + GPW          +  + RP        
Sbjct: 123 RLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPG 182

Query: 110 -----------------------AWPGALGGPERVTFHSTPGPKATVAASHLRVE----- 141
                                  A+    G P    F  +PG +  V ++ L +      
Sbjct: 183 EDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLN 242

Query: 142 -FGGQA------------GLAAAGLRGRCQCHGHAARCAAR-ARPPRCHCRHHTTGPGCE 187
            FG                ++   + GRC+C+GHA+ C    A    C C+H+TTG  CE
Sbjct: 243 TFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCE 302

Query: 188 SCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTA 247
            C P  +D PW   T    H CLPC+C+  +  C F+ ELFR +G   GG C  CR HTA
Sbjct: 303 RCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTG--HGGRCHHCRDHTA 360

Query: 248 GRHCHYCQPGFWR-DPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCN 306
           G HC  CQ  F+  DP  P      C+ C C   G+    C+ T G C CK  VTG  C+
Sbjct: 361 GPHCERCQENFYHWDPRMP------CQPCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCD 413

Query: 307 RCGPGYQ---------------------QSRSPRMPCQRIPEATTTLATTPGAYSSDPQC 345
           RC PG+                        RS R PC+   E        PG ++  P  
Sbjct: 414 RCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHN 473

Query: 346 QNYCN 350
              C+
Sbjct: 474 PAGCS 478



 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 57/161 (35%), Positives = 75/161 (46%), Gaps = 19/161 (11%)

Query: 156 RCQCHGHAARCAARARPP---RC-HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLP 211
           +CQC G+    A     P    C  C H+TTG  CE C+            PR    C+P
Sbjct: 809 QCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYG---SALAPRPADKCMP 865

Query: 212 CSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRA 271
           CSC+         S   ++      G C  C  H   R C  C PGF+    QP    R 
Sbjct: 866 CSCHPQG------SVSEQMPCDPVTGQCS-CLPHVTARDCSRCYPGFF--DLQP---GRG 913

Query: 272 CRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
           CR+C+CHP+G+    C+  +GQCTC+ GVTG  C+RC  G+
Sbjct: 914 CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGF 954



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 54/184 (29%), Positives = 67/184 (36%), Gaps = 24/184 (13%)

Query: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
           C C+ H            C C HHT GP CE C P     P+          C PC C  
Sbjct: 707 CTCNQHGT---CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQAD----DCQPCPCPG 759

Query: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276
            +  C    E   +       VC  C     GR C  C  GF+ DP       + C  CQ
Sbjct: 760 QSA-CTTIPESREV-------VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQ 811

Query: 277 C--HPIGATGGTCNQTSGQC-TCKLGVTGLTCNRCGPG-YQQSRSPR-----MPCQRIPE 327
           C  +      G C+  SG C  C    TG  C  C  G Y  + +PR     MPC   P+
Sbjct: 812 CSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQ 871

Query: 328 ATTT 331
            + +
Sbjct: 872 GSVS 875



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 47/142 (33%), Positives = 60/142 (42%), Gaps = 25/142 (17%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP-CLPCSCNQHARRCRFNSELFRLSGG 233
           C C    TG  CESC P ++    R      P+  C+PC+CNQH   C  N+        
Sbjct: 673 CSCPTGYTGQFCESCAPGYK----REMPQGGPYASCVPCTCNQHG-TCDPNT-------- 719

Query: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRA--CRACQCHPIGATGGTCNQTS 291
              G+C  C HHT G  C  C PGF+ +P    F+ +A  C+ C C    A         
Sbjct: 720 ---GICV-CSHHTEGPSCERCLPGFYGNP----FAGQADDCQPCPCPGQSACTTIPESRE 771

Query: 292 GQCT-CKLGVTGLTCNRCGPGY 312
             CT C  G  G  C  C  G+
Sbjct: 772 VVCTHCPPGQRGRRCEVCDDGF 793



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 6/78 (7%)

Query: 144 GQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATP 203
           G   L+  G R  C C+   +      R  RC C+ +  G  C+ CRP   +       P
Sbjct: 418 GFHSLSEGGCRP-CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFN-----LQP 471

Query: 204 RHPHPCLPCSCNQHARRC 221
            +P  C  C C  H++ C
Sbjct: 472 HNPAGCSSCFCYGHSKVC 489



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 10/21 (47%), Positives = 13/21 (61%)

Query: 294 CTCKLGVTGLTCNRCGPGYQQ 314
           C+C  G TG  C  C PGY++
Sbjct: 673 CSCPTGYTGQFCESCAPGYKR 693


>gi|143770880 laminin, beta 4 [Homo sapiens]
          Length = 1761

 Score =  163 bits (412), Expect = 4e-40
 Identities = 79/193 (40%), Positives = 105/193 (54%), Gaps = 22/193 (11%)

Query: 153 LRGRCQCHGHAARCAARAR-------PP-----RCHCRHHTTGPGCESCRPSHRDWPWRP 200
           +RG C C+GHA+ C    +       PP     +C C+H+T GP CE C+   +D PWRP
Sbjct: 261 VRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRP 320

Query: 201 ATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWR 260
           A     + C  CSCN H+ RC F+   +  SGG SGGVCE C+H+T G+HC  C+P F+R
Sbjct: 321 AADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYR 380

Query: 261 DPSQPIFSRRACRACQCHPIGA-TGGTC--------NQTSGQCTCKLGVTGLTCNRCGPG 311
           DP + I    AC  C+C P G  +GG C           +GQC CK  V G  C++C P 
Sbjct: 381 DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPN 440

Query: 312 -YQQSRSPRMPCQ 323
            Y  S +  + CQ
Sbjct: 441 HYGLSATDPLGCQ 453



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 41/139 (29%), Positives = 57/139 (41%), Gaps = 17/139 (12%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
           +C C+ +  G  C+ C+P+H        +   P  C PC CN           L  L+  
Sbjct: 422 QCLCKENVEGAKCDQCKPNHYG-----LSATDPLGCQPCDCNPLG-------SLPFLTCD 469

Query: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
              G C  C  +  G HC  C  G+W   +        C  C C   GA    C+  +GQ
Sbjct: 470 VDTGQC-LCLSYVTGAHCEECTVGYWGLGNH----LHGCSPCDCDIGGAYSNVCSPKNGQ 524

Query: 294 CTCKLGVTGLTCNRCGPGY 312
           C C+  VTG +C+   PGY
Sbjct: 525 CECRPHVTGRSCSEPAPGY 543



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 54/204 (26%), Positives = 74/204 (36%), Gaps = 45/204 (22%)

Query: 143  GGQAGLAAAGLRGRCQCHGHAAR-CAARAR-----PPRC--------HCRHHTTGPGCES 188
            G Q G  + G  G  +  G   + CA         P  C         C H+T G  C+ 
Sbjct: 946  GTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQL 1005

Query: 189  CRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFN-SELFRLSGGRSGGVCE------- 240
            C+P H                   + NQ  RRC  + S +  +     GG C        
Sbjct: 1006 CKPGHYG----------------SALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGA 1049

Query: 241  -RCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLG 299
              C  +  G  C  C  G+W      +   R C++C C P  +    C+Q +GQC CKLG
Sbjct: 1050 CPCLPNVTGLACDRCADGYWN-----LVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLG 1104

Query: 300  VTGLTCNRCGPGYQQSRSPR-MPC 322
              G  C+ C   Y      R +PC
Sbjct: 1105 YGGKRCSECQENYYGDPPGRCIPC 1128



 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 46/189 (24%), Positives = 64/189 (33%), Gaps = 32/189 (16%)

Query: 144  GQAGLAAAGLRGRCQCHGHAAR----------CAARARPPRCHCRHHTTGPGCESCRPSH 193
            G  G A      RC CH               C        C C  + TG  C+ C   +
Sbjct: 1009 GHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGY 1068

Query: 194  RDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHY 253
              W   P        C  C C+    +     +L         G C  C+    G+ C  
Sbjct: 1069 --WNLVPG-----RGCQSCDCDPRTSQSSHCDQLT--------GQCP-CKLGYGGKRCSE 1112

Query: 254  CQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQ 313
            CQ  ++ DP         C  C C+  G     C+  +G C C+ GV+G  C+RC  G+ 
Sbjct: 1113 CQENYYGDPPG------RCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHS 1166

Query: 314  QSRSPRMPC 322
            Q     + C
Sbjct: 1167 QEFPTCLQC 1175



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 47/177 (26%), Positives = 65/177 (36%), Gaps = 35/177 (19%)

Query: 157 CQCHGHAARCAARARPP-RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
           C CH   ++     +   +C C    +G  C+ C   +  +P           C PC CN
Sbjct: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCN 866

Query: 216 QHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRAC 275
           + A  C   +           G C  C   T GR+C  C  G++ +PS    S + CR C
Sbjct: 867 RFAELCDPET-----------GSCFNCGGFTTGRNCERCIDGYYGNPS----SGQPCRPC 911

Query: 276 QCHPIGAT----GGTCNQTSGQ----CTCKLGVTGLTCNRCGPG-YQQSRSPRMPCQ 323
            C    ++      +C Q        C C  G TG  C  C  G Y   R    PCQ
Sbjct: 912 LCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQ 968



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 231 SGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQT 290
           S  R GG C+ C+    GR C  C  G +            C  C CHP G+    C+Q 
Sbjct: 780 SCSRLGGQCQ-CKPLVVGRCCDRCSTGSYD------LGHHGCHPCHCHPQGSKDTVCDQV 832

Query: 291 SGQCTCKLGVTGLTCNRCGPGYQQSRSPR-MPCQRIPE 327
           +GQC C   V+G  C+RC  GY    S    PC R  E
Sbjct: 833 TGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAE 870



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 274 ACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPG-YQQSRSPRMPCQRIPEAT 329
           AC+CHP G+ G +C++  GQC CK  V G  C+RC  G Y        PC   P+ +
Sbjct: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 15/89 (16%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
           +C C  + TG  CE C   +    W      H H C PC C+         S        
Sbjct: 474 QCLCLSYVTGAHCEECTVGY----W--GLGNHLHGCSPCDCDIGGAYSNVCSP------- 520

Query: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDP 262
              G CE CR H  GR C    PG++  P
Sbjct: 521 -KNGQCE-CRPHVTGRSCSEPAPGYFFAP 547


>gi|93204871 netrin 4 [Homo sapiens]
          Length = 628

 Score =  161 bits (407), Expect = 1e-39
 Identities = 106/377 (28%), Positives = 168/377 (44%), Gaps = 67/377 (17%)

Query: 153 LRGRCQCHGHAARCAA-----RARPP--------RCHCRHHTTGPGCESCRPSHRDWPWR 199
           ++G C C+GHA +C         + P        +C C+H+T G  C+ C P + D PW 
Sbjct: 258 VKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWE 317

Query: 200 PATPRH--PHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPG 257
            A  +   P+ C  C CN HA  C F+  ++  SG RSGGVC+ C+H+T G++C  C+PG
Sbjct: 318 AADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377

Query: 258 FWRDPSQPIFSRRACRACQCHPIGA------TGGTCNQTSGQCTCKLGVTGLTCNRCGPG 311
           F+RD  +P  +  AC+ C CHP+G+      +   C+ ++G C CK GV G  C+RC  G
Sbjct: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVG 437

Query: 312 YQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTR-VHM------------ 358
           Y         C+    A +    T    SS      Y  + D R VH             
Sbjct: 438 YWGFGD--YGCRPCDCAGSCDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQ 495

Query: 359 -------------------SLRRYC--QQDHVLRAQVLASEAAGPAWQRLAVRVLAVYKQ 397
                              + + +C  +  +VL+ ++L++   G   + + V++  V K 
Sbjct: 496 GFSALLHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGTHVE-VNVKIKKVLKS 554

Query: 398 RAQPVRRGDQ----DAWVPRADLTCGCLRLQPGTDYLLLGSAVGDPDPTRLILDRHGLAL 453
               + RG +    ++W  R    C C  L PG +YL+ G    D    +LI++      
Sbjct: 555 TKLKIFRGKRTLYPESWTDRG---CTCPILNPGLEYLVAGHE--DIRTGKLIVNMKSFVQ 609

Query: 454 PWRPRWARPLKRLQQEE 470
            W+P   R +  + + E
Sbjct: 610 HWKPSLGRKVMDILKRE 626


>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
          Length = 1172

 Score =  156 bits (395), Expect = 4e-38
 Identities = 78/196 (39%), Positives = 100/196 (51%), Gaps = 25/196 (12%)

Query: 129 PKATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCA----ARARPPR-------CHC 177
           P A  A S LR             L+G C CHGHA RCA    A A P         C C
Sbjct: 235 PSAYYAVSQLR-------------LQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVC 281

Query: 178 RHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGG 237
           +H+T GP CE C P + + PWRPA  +  H C  C CN H+  C F+  +F  S G  GG
Sbjct: 282 QHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGG 341

Query: 238 VCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGAT-GGTCNQTSGQCTC 296
           VC+ CR HT G++C  CQ  ++R+       +  C +C+C P GA  G  C+  +GQC C
Sbjct: 342 VCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVC 401

Query: 297 KLGVTGLTCNRCGPGY 312
           K  V G  C+ C PG+
Sbjct: 402 KEHVQGERCDLCKPGF 417



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 54/178 (30%), Positives = 73/178 (41%), Gaps = 31/178 (17%)

Query: 144 GQAGLAAAGLRG--RCQCH--GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWR 199
           G  GL  A  +G  RC C+  G            RC C  +  GP C+ C P H    W+
Sbjct: 416 GFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WK 471

Query: 200 PATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHC-----HYC 254
            A+ +    C PC+C+ H      NS        +  G C  CR    G  C       C
Sbjct: 472 LASGQG---CEPCACDPH------NS--LSPQCNQFTGQCP-CREGFGGLMCSAAAIRQC 519

Query: 255 QPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
               + D +        CRAC C   G  G  C++ SG+C C+ G+TG  C++C  GY
Sbjct: 520 PDRTYGDVAT------GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571


>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
          Length = 1172

 Score =  156 bits (395), Expect = 4e-38
 Identities = 78/196 (39%), Positives = 100/196 (51%), Gaps = 25/196 (12%)

Query: 129 PKATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCA----ARARPPR-------CHC 177
           P A  A S LR             L+G C CHGHA RCA    A A P         C C
Sbjct: 235 PSAYYAVSQLR-------------LQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVC 281

Query: 178 RHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGG 237
           +H+T GP CE C P + + PWRPA  +  H C  C CN H+  C F+  +F  S G  GG
Sbjct: 282 QHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGG 341

Query: 238 VCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGAT-GGTCNQTSGQCTC 296
           VC+ CR HT G++C  CQ  ++R+       +  C +C+C P GA  G  C+  +GQC C
Sbjct: 342 VCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVC 401

Query: 297 KLGVTGLTCNRCGPGY 312
           K  V G  C+ C PG+
Sbjct: 402 KEHVQGERCDLCKPGF 417



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 54/178 (30%), Positives = 73/178 (41%), Gaps = 31/178 (17%)

Query: 144 GQAGLAAAGLRG--RCQCH--GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWR 199
           G  GL  A  +G  RC C+  G            RC C  +  GP C+ C P H    W+
Sbjct: 416 GFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WK 471

Query: 200 PATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHC-----HYC 254
            A+ +    C PC+C+ H      NS        +  G C  CR    G  C       C
Sbjct: 472 LASGQG---CEPCACDPH------NS--LSPQCNQFTGQCP-CREGFGGLMCSAAAIRQC 519

Query: 255 QPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
               + D +        CRAC C   G  G  C++ SG+C C+ G+TG  C++C  GY
Sbjct: 520 PDRTYGDVAT------GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571


>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
          Length = 1172

 Score =  156 bits (395), Expect = 4e-38
 Identities = 78/196 (39%), Positives = 100/196 (51%), Gaps = 25/196 (12%)

Query: 129 PKATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCA----ARARPPR-------CHC 177
           P A  A S LR             L+G C CHGHA RCA    A A P         C C
Sbjct: 235 PSAYYAVSQLR-------------LQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVC 281

Query: 178 RHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGG 237
           +H+T GP CE C P + + PWRPA  +  H C  C CN H+  C F+  +F  S G  GG
Sbjct: 282 QHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGG 341

Query: 238 VCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGAT-GGTCNQTSGQCTC 296
           VC+ CR HT G++C  CQ  ++R+       +  C +C+C P GA  G  C+  +GQC C
Sbjct: 342 VCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVC 401

Query: 297 KLGVTGLTCNRCGPGY 312
           K  V G  C+ C PG+
Sbjct: 402 KEHVQGERCDLCKPGF 417



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 54/178 (30%), Positives = 73/178 (41%), Gaps = 31/178 (17%)

Query: 144 GQAGLAAAGLRG--RCQCH--GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWR 199
           G  GL  A  +G  RC C+  G            RC C  +  GP C+ C P H    W+
Sbjct: 416 GFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WK 471

Query: 200 PATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHC-----HYC 254
            A+ +    C PC+C+ H      NS        +  G C  CR    G  C       C
Sbjct: 472 LASGQG---CEPCACDPH------NS--LSPQCNQFTGQCP-CREGFGGLMCSAAAIRQC 519

Query: 255 QPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
               + D +        CRAC C   G  G  C++ SG+C C+ G+TG  C++C  GY
Sbjct: 520 PDRTYGDVAT------GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571


>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
          Length = 1609

 Score =  150 bits (378), Expect = 3e-36
 Identities = 112/427 (26%), Positives = 161/427 (37%), Gaps = 118/427 (27%)

Query: 13  QATADPCYDPQGRPQFCLPPVTQLAA-VAASCPQACALSPGNHL------GARETCNG-- 63
           QA  D C D  GRPQ C+P     A  V       C   P  +       G  ++C+   
Sbjct: 34  QAAMDECTDEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCD 93

Query: 64  ----------------------------------------SLTLALGGPFLLTSVSLRFC 83
                                                   +LTL LG  F +T V L+F 
Sbjct: 94  AGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFH 153

Query: 84  TPGPPALILSAAWASGGPW----------------------------------------- 102
           T  P +  +       GPW                                         
Sbjct: 154 TSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDIS 213

Query: 103 RLLWHRPAWPGALGGPERVTFHSTPGPKATVAASHLRVE------FGGQA---------- 146
            L     A+    G P    F ++P  +  V A+ +RV       FG +           
Sbjct: 214 PLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSY 273

Query: 147 --GLAAAGLRGRCQCHGHAARCAARARPPR-CHCRHHTTGPGCESCRPSHRDWPWRPATP 203
              ++   + GRC+C+GHA+ C         C+C+H+T G  CE C P   D PWR AT 
Sbjct: 274 YYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATA 333

Query: 204 RHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPS 263
                CLPC CN  ++ C F+ EL+R +G   GG C  C+ +T G HC  C+  F+R   
Sbjct: 334 ESASECLPCDCNGRSQECYFDPELYRSTG--HGGHCTNCQDNTDGAHCERCRENFFR--- 388

Query: 264 QPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQ-SRSPRMPC 322
             + +  AC +C C P+G+    C+ + G+C+CK GV G  C+RC PG+   + +   PC
Sbjct: 389 --LGNNEACSSCHCSPVGSLSTQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPC 445

Query: 323 QRIPEAT 329
              P  +
Sbjct: 446 SCDPSGS 452



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 49/161 (30%), Positives = 71/161 (44%), Gaps = 24/161 (14%)

Query: 177 CRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSG 236
           C ++T G  C+ C+         P  P     C  C+CN +    +      + S     
Sbjct: 852 CIYNTAGFYCDRCKDGFFG---NPLAPNPADKCKACNCNLYGTMKQ------QSSCNPVT 902

Query: 237 GVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTC 296
           G CE C  H  G+ C  C PGF+      + S + C  C CH +G+T G C+  +GQC C
Sbjct: 903 GQCE-CLPHVTGQDCGACDPGFYN-----LQSGQGCERCDCHALGSTNGQCDIRTGQCEC 956

Query: 297 KLGVTGLTCNRC-----GPGYQQSRSPRMPCQRIPEATTTL 332
           + G+TG  C RC     G G +  +    PC   PE + +L
Sbjct: 957 QPGITGQHCERCEVNHFGFGPEGCK----PCDCHPEGSLSL 993



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 58/219 (26%), Positives = 85/219 (38%), Gaps = 59/219 (26%)

Query: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC-- 214
           C C+GH+  C        C+CR +T GP CE C   +    +  +T      C PC C  
Sbjct: 724 CACNGHSETCDPETGV--CNCRDNTAGPHCEKCSDGY----YGDSTAGTSSDCQPCPCPG 777

Query: 215 --------------------NQHARRCRFNSE-LFRLSGGRSG----------------- 236
                                   +RC    +  F    GR+G                 
Sbjct: 778 GSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPN 837

Query: 237 ---------GVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGA--TGG 285
                    G C +C ++TAG +C  C+ GF+ +P  P  + + C+AC C+  G      
Sbjct: 838 AVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADK-CKACNCNLYGTMKQQS 896

Query: 286 TCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQR 324
           +CN  +GQC C   VTG  C  C PG+   +S +  C+R
Sbjct: 897 SCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQ-GCER 934



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 46/141 (32%), Positives = 59/141 (41%), Gaps = 22/141 (15%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPH-PCLPCSCNQHARRCRFNSELFRLSGG 233
           C C     G  CE C   +R    R      P+ PC+ C+CN H+  C            
Sbjct: 690 CTCPVGYGGQFCEMCLSGYR----RETPNLGPYSPCVLCACNGHSETC-----------D 734

Query: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSG- 292
              GVC  CR +TAG HC  C  G++ D +    S   C+ C C P G++     +T   
Sbjct: 735 PETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSS--DCQPCPC-PGGSSCAVVPKTKEV 790

Query: 293 QCT-CKLGVTGLTCNRCGPGY 312
            CT C  G TG  C  C  GY
Sbjct: 791 VCTNCPTGTTGKRCELCDDGY 811



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 42/159 (26%), Positives = 59/159 (37%), Gaps = 36/159 (22%)

Query: 174  RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
            +C C  H TG  C +C P   +        +    C  C C  HA              G
Sbjct: 904  QCECLPHVTGQDCGACDPGFYNL-------QSGQGCERCDC--HAL-------------G 941

Query: 234  RSGGVCE------RCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTC 287
             + G C+       C+    G+HC  C+   +       F    C+ C CHP G+    C
Sbjct: 942  STNGQCDIRTGQCECQPGITGQHCERCEVNHFG------FGPEGCKPCDCHPEGSLSLQC 995

Query: 288  NQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIP 326
                G+C C+ G  G  C++C   Y  +RS    CQ  P
Sbjct: 996  KD-DGRCECREGFVGNRCDQCEENYFYNRS-WPGCQECP 1032



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 27/124 (21%)

Query: 156  RCQCHG-HAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC 214
            RC CH   +       R  +C C+   TG  CE C  +H  +         P  C PC C
Sbjct: 934  RCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGF--------GPEGCKPCDC 985

Query: 215  NQH---ARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRA 271
            +     + +C            +  G CE CR    G  C  C+  ++ + S P    + 
Sbjct: 986  HPEGSLSLQC------------KDDGRCE-CREGFVGNRCDQCEENYFYNRSWP--GCQE 1030

Query: 272  CRAC 275
            C AC
Sbjct: 1031 CPAC 1034



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 6/78 (7%)

Query: 144 GQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATP 203
           G   L  AG R  C C    +         RC C+ +  G  CE C+P   +        
Sbjct: 433 GFHSLTEAGCRP-CSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFN-----LES 486

Query: 204 RHPHPCLPCSCNQHARRC 221
            +P  C PC C  H+  C
Sbjct: 487 SNPRGCTPCFCFGHSSVC 504


>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
          Length = 1786

 Score =  149 bits (375), Expect = 7e-36
 Identities = 79/225 (35%), Positives = 109/225 (48%), Gaps = 22/225 (9%)

Query: 153 LRGRCQCHGHAARCAA---------RARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATP 203
           +RG C C+GHA+ CA                C CRH+T G  CE C   + D PWRPA  
Sbjct: 267 VRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEG 326

Query: 204 RHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPS 263
           R+ + C  C+CN+H+  C F+  ++  +G  SGGVC+ C+H+T GR+C  C+P +++ P 
Sbjct: 327 RNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE 386

Query: 264 QPIFSRRACRACQCHPIGATG-GTCNQ--------TSGQCTCKLGVTGLTCNRCGPG-YQ 313
           + I     C  C C P G+   G C+          +GQC CKL V G  C+ C  G Y 
Sbjct: 387 RDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYD 446

Query: 314 QSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQN-YCNMSDTRVH 357
            S      C+    A   L T PG    D +  + YC    T  H
Sbjct: 447 LSSEDPFGCKSC--ACNPLGTIPGGNPCDSETGHCYCKRLVTGQH 489



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 53/170 (31%), Positives = 70/170 (41%), Gaps = 22/170 (12%)

Query: 155  GRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC 214
            G  Q H + + C       +C C  +  G  C+ C P+     W+ A+      C PC+C
Sbjct: 1034 GTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN----TWQLASGTG---CDPCNC 1086

Query: 215  NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRA 274
            N         +  F  S     G C+ C     GR C  CQ  FW DP         CRA
Sbjct: 1087 NA--------AHSFGPSCNEFTGQCQ-CMPGFGGRTCSECQELFWGDPDVE------CRA 1131

Query: 275  CQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQR 324
            C C P G     C+Q++GQC C  GV G  C++C  GY        PC +
Sbjct: 1132 CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQ 1181



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 58/219 (26%), Positives = 80/219 (36%), Gaps = 66/219 (30%)

Query: 157  CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC---- 212
            CQC+GHA  C         +C+ +T G  CE C   +   P    +  H  PC PC    
Sbjct: 867  CQCNGHADDCDP-VTGECLNCQDYTMGHNCERCLAGYYGDPII-GSGDHCRPC-PCPDGP 923

Query: 213  -SCNQHARRCRFNSELFRLS--------------------------GG------------ 233
             S  Q AR C  +    +L+                          GG            
Sbjct: 924  DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNID 983

Query: 234  --------RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGG 285
                    +  G C +C +HT G HC +C+ G++ D  Q     + CR C C+ +G    
Sbjct: 984  TTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQ-----QDCRKCVCNYLGTVQE 1038

Query: 286  TCN-------QTSGQCTCKLGVTGLTCNRCGPGYQQSRS 317
             CN       + +GQC C   V G  C+RC P   Q  S
Sbjct: 1039 HCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLAS 1077



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 52/179 (29%), Positives = 66/179 (36%), Gaps = 35/179 (19%)

Query: 144 GQAGLAAAGLRGRCQCHGHAARCA-ARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPAT 202
           G  G   +G +  C+CH   +  A       +CHC        C+ C P H  +P     
Sbjct: 809 GTFGFGPSGCKP-CECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP----- 862

Query: 203 PRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDP 262
                 C PC CN HA  C               G C  C+ +T G +C  C  G++ DP
Sbjct: 863 -----SCQPCQCNGHADDC-----------DPVTGECLNCQDYTMGHNCERCLAGYYGDP 906

Query: 263 SQPIFSRRACRACQCHPIGATGG-----TCNQ----TSGQCTCKLGVTGLTCNRCGPGY 312
              I S   CR C C P G   G     +C Q        C C  G  G  C+ C  GY
Sbjct: 907 I--IGSGDHCRPCPC-PDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGY 962



 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 54/220 (24%), Positives = 80/220 (36%), Gaps = 69/220 (31%)

Query: 156 RCQCHGHAARC---------AARARPPRCH-CRHHTTGPGCESCRPSHRDWPWRPATPRH 205
           +C C+ H+  C                 C  C+H+T G  CE C+P +   P R    R 
Sbjct: 334 KCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI--RD 391

Query: 206 PHPCLPCSCNQHARRCRFNSELFR-LSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQ 264
           P+ C  C+C+    +     + +   S G   G C RC+ +  G HC  C+ GF+   S+
Sbjct: 392 PNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYDLSSE 450

Query: 265 PIFSRRACRACQCHPIGA--------------------TGGTCNQT-------------- 290
             F    C++C C+P+G                     TG  C+Q               
Sbjct: 451 DPFG---CKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGC 507

Query: 291 ------------------SGQCTCKLGVTGLTCNRCGPGY 312
                             SGQC+C+  + G  CN   PGY
Sbjct: 508 RPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGY 547



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 34/89 (38%), Positives = 46/89 (51%), Gaps = 8/89 (8%)

Query: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
           +GG C+ CR +  GR C+ C PG +       F    C+ C+CH  G+    CN  +GQC
Sbjct: 788 NGGQCQ-CRPNVVGRTCNRCAPGTFG------FGPSGCKPCECHLQGSVNAFCNPVTGQC 840

Query: 295 TCKLGVTGLTCNRCGPGYQQSRSPRMPCQ 323
            C  GV    C+RC PG+    S + PCQ
Sbjct: 841 HCFQGVYARQCDRCLPGHWGFPSCQ-PCQ 868



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 38/140 (27%), Positives = 50/140 (35%), Gaps = 29/140 (20%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
           +C CR +  G  C  C P    +         P  C PC C+       F + +      
Sbjct: 791 QCQCRPNVVGRTCNRCAPGTFGF--------GPSGCKPCECHLQGSVNAFCNPV------ 836

Query: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
              G C  C      R C  C PG W  PS        C+ CQC+        C+  +G+
Sbjct: 837 --TGQC-HCFQGVYARQCDRCLPGHWGFPS--------CQPCQCN---GHADDCDPVTGE 882

Query: 294 C-TCKLGVTGLTCNRCGPGY 312
           C  C+    G  C RC  GY
Sbjct: 883 CLNCQDYTMGHNCERCLAGY 902



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 19/38 (50%), Positives = 23/38 (60%)

Query: 274 ACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPG 311
           AC+C P G+    C+   GQC C+  V G TCNRC PG
Sbjct: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPG 809



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 15/85 (17%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
           C+C+   TG  C+ C P H    W          C PC C+        N+  F  SG  
Sbjct: 479 CYCKRLVTGQHCDQCLPEH----W--GLSNDLDGCRPCDCDLGGA---LNNSCFAESGQC 529

Query: 235 SGGVCERCRHHTAGRHCHYCQPGFW 259
           S      CR H  GR C+  +PG++
Sbjct: 530 S------CRPHMIGRQCNEVEPGYY 548


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score =  144 bits (362), Expect = 2e-34
 Identities = 81/226 (35%), Positives = 108/226 (47%), Gaps = 29/226 (12%)

Query: 112 PGALGGPERVTFHSTPGPKATVAASHLRVEFGGQ--AGLAAAGLR------------GRC 157
           PG    P    F++TP  +  V A+ +R  F GQ      A  LR            GRC
Sbjct: 459 PGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRC 518

Query: 158 QCHGHAARCAARARPPRCHCRHH--TTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
           QCHGHA  C   ++P RC C     T G  C+ C P + D P+R     +   C PC CN
Sbjct: 519 QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCN 578

Query: 216 QHARRCRFNS-------ELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFS 268
            H++ C +N        E FR  GG  GGVC+ C H+T GR+C  C+  F+R       +
Sbjct: 579 SHSKSCHYNISVDPFPFEHFR--GG--GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSA 634

Query: 269 RRACRACQCHPIGATGGT--CNQTSGQCTCKLGVTGLTCNRCGPGY 312
              C+ C C  +G   G+  C+Q  GQC CK  V+G  CN+C  G+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGF 680



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 37/203 (18%)

Query: 157 CQCHGHAA-RCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
           CQC+ H +          +C C+    G  C++CR +                C  C C+
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN--------CKACDCD 798

Query: 216 QHARRCRFNSELFRLSGGRSGGVCER------CRHHTAGRHCHYCQPGFWRDPSQPIFSR 269
                          +G   G VC        C+ +  GR C+ C  G +       F  
Sbjct: 799 T--------------AGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF-- 842

Query: 270 RACRACQCHPIGATGGT--CNQTSGQCTCKLGVTGLTCNRCGP-GYQQSRSPRMPCQRIP 326
             C  C C   G   G+  CN+++GQC CKLGVTGL CN+C P  Y  +      CQ   
Sbjct: 843 -LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC- 900

Query: 327 EATTTLATTPGAYSSDPQCQNYC 349
               +L T PG        Q  C
Sbjct: 901 -ECDSLGTLPGTICDPISGQCLC 922



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 42/140 (30%), Positives = 57/140 (40%), Gaps = 25/140 (17%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHAR-----RCRFNSELF 228
           +C+C+ H +G  C  C+    +          P  C PC+CN          C  NS   
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYN-----LQELDPDGCSPCNCNTSGTVDGDITCHQNS--- 712

Query: 229 RLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCN 288
                   G C +C+ +  G  C +C  GF    S   F+   C  CQC+  G+    CN
Sbjct: 713 --------GQC-KCKANVIGLRCDHCNFGFKFLRS---FNDVGCEPCQCNLHGSVNKFCN 760

Query: 289 QTSGQCTCKLGVTGLTCNRC 308
             SGQC CK    GL C+ C
Sbjct: 761 PHSGQCECKKEAKGLQCDTC 780



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 44/167 (26%), Positives = 67/167 (40%), Gaps = 16/167 (9%)

Query: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
           C   G        A+  +C C+ +  G  C  C   +           +   CLPC+C++
Sbjct: 797 CDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFY-----LRQNNSFLCLPCNCDK 851

Query: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276
                  N  L      +S G C  C+    G  C+ C+P  +   +  I + + C+ C+
Sbjct: 852 TGT---INGSLLC---NKSTGQCP-CKLGVTGLRCNQCEPHRY---NLTIDNFQHCQMCE 901

Query: 277 CHPIGATGGT-CNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
           C  +G   GT C+  SGQC C     G  CN+C PG+  S      C
Sbjct: 902 CDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 40/137 (29%), Positives = 55/137 (40%), Gaps = 18/137 (13%)

Query: 174  RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
            +C C  +  G  C  C+P          +P +   CLPCSC+         + L      
Sbjct: 919  QCLCVPNRQGRRCNQCQPGFY------ISPGNATGCLPCSCHTTGAVNHICNSLT----- 967

Query: 234  RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
               G C       AG+ C  C+  ++    Q       C+ C CH  GA   TC+  +GQ
Sbjct: 968  ---GQCVCQDASIAGQRCDQCKDHYFGFDPQT----GRCQPCNCHLSGALNETCHLVTGQ 1020

Query: 294  CTCKLGVTGLTCNRCGP 310
            C CK  VTG  C+ C P
Sbjct: 1021 CFCKQFVTGSKCDACVP 1037


>gi|219842259 usherin isoform A [Homo sapiens]
          Length = 1546

 Score =  144 bits (362), Expect = 2e-34
 Identities = 81/226 (35%), Positives = 108/226 (47%), Gaps = 29/226 (12%)

Query: 112 PGALGGPERVTFHSTPGPKATVAASHLRVEFGGQ--AGLAAAGLR------------GRC 157
           PG    P    F++TP  +  V A+ +R  F GQ      A  LR            GRC
Sbjct: 459 PGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHRYYAVDEITISGRC 518

Query: 158 QCHGHAARCAARARPPRCHCRHH--TTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
           QCHGHA  C   ++P RC C     T G  C+ C P + D P+R     +   C PC CN
Sbjct: 519 QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCN 578

Query: 216 QHARRCRFNS-------ELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFS 268
            H++ C +N        E FR  GG  GGVC+ C H+T GR+C  C+  F+R       +
Sbjct: 579 SHSKSCHYNISVDPFPFEHFR--GG--GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSA 634

Query: 269 RRACRACQCHPIGATGGT--CNQTSGQCTCKLGVTGLTCNRCGPGY 312
              C+ C C  +G   G+  C+Q  GQC CK  V+G  CN+C  G+
Sbjct: 635 IDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGF 680



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 37/203 (18%)

Query: 157 CQCHGHAA-RCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
           CQC+ H +          +C C+    G  C++CR +                C  C C+
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN--------CKACDCD 798

Query: 216 QHARRCRFNSELFRLSGGRSGGVCER------CRHHTAGRHCHYCQPGFWRDPSQPIFSR 269
                          +G   G VC        C+ +  GR C+ C  G +       F  
Sbjct: 799 T--------------AGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF-- 842

Query: 270 RACRACQCHPIGATGGT--CNQTSGQCTCKLGVTGLTCNRCGP-GYQQSRSPRMPCQRIP 326
             C  C C   G   G+  CN+++GQC CKLGVTGL CN+C P  Y  +      CQ   
Sbjct: 843 -LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMC- 900

Query: 327 EATTTLATTPGAYSSDPQCQNYC 349
               +L T PG        Q  C
Sbjct: 901 -ECDSLGTLPGTICDPISGQCLC 922



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 42/140 (30%), Positives = 57/140 (40%), Gaps = 25/140 (17%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHAR-----RCRFNSELF 228
           +C+C+ H +G  C  C+    +          P  C PC+CN          C  NS   
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFYN-----LQELDPDGCSPCNCNTSGTVDGDITCHQNS--- 712

Query: 229 RLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCN 288
                   G C +C+ +  G  C +C  GF    S   F+   C  CQC+  G+    CN
Sbjct: 713 --------GQC-KCKANVIGLRCDHCNFGFKFLRS---FNDVGCEPCQCNLHGSVNKFCN 760

Query: 289 QTSGQCTCKLGVTGLTCNRC 308
             SGQC CK    GL C+ C
Sbjct: 761 PHSGQCECKKEAKGLQCDTC 780



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 44/167 (26%), Positives = 67/167 (40%), Gaps = 16/167 (9%)

Query: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
           C   G        A+  +C C+ +  G  C  C   +           +   CLPC+C++
Sbjct: 797 CDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFY-----LRQNNSFLCLPCNCDK 851

Query: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276
                  N  L      +S G C  C+    G  C+ C+P  +   +  I + + C+ C+
Sbjct: 852 TGT---INGSLLC---NKSTGQCP-CKLGVTGLRCNQCEPHRY---NLTIDNFQHCQMCE 901

Query: 277 CHPIGATGGT-CNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
           C  +G   GT C+  SGQC C     G  CN+C PG+  S      C
Sbjct: 902 CDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGC 948



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 40/137 (29%), Positives = 55/137 (40%), Gaps = 18/137 (13%)

Query: 174  RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
            +C C  +  G  C  C+P          +P +   CLPCSC+         + L      
Sbjct: 919  QCLCVPNRQGRRCNQCQPGFY------ISPGNATGCLPCSCHTTGAVNHICNSLT----- 967

Query: 234  RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
               G C       AG+ C  C+  ++    Q       C+ C CH  GA   TC+  +GQ
Sbjct: 968  ---GQCVCQDASIAGQRCDQCKDHYFGFDPQT----GRCQPCNCHLSGALNETCHLVTGQ 1020

Query: 294  CTCKLGVTGLTCNRCGP 310
            C CK  VTG  C+ C P
Sbjct: 1021 CFCKQFVTGSKCDACVP 1037


>gi|21264602 laminin alpha 5 [Homo sapiens]
          Length = 3695

 Score =  142 bits (359), Expect = 5e-34
 Identities = 74/215 (34%), Positives = 102/215 (47%), Gaps = 26/215 (12%)

Query: 155 GRCQCHGHAARCAARARPP----RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCL 210
           GRC CHGHA  C A+        +C C+H+T G  C+ C P     PW+PAT    + C 
Sbjct: 298 GRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQ 357

Query: 211 PCSCNQHARRCRFNSELFRLSGGRS-------GGVCERCRHHTAGRHCHYCQPGFWRDPS 263
            C+C  HA  C ++ E+ R    +S       GGVC  C+HHT G +C  C PGF+R P+
Sbjct: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417

Query: 264 QPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY----------- 312
            P+ S   CR C C     T GTC   +G+C C+   +G  C+ C  G+           
Sbjct: 418 HPLDSPHVCRRCNCES-DFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPS 476

Query: 313 --QQSRSPRMPCQRIPEATTTLATTPG-AYSSDPQ 344
               +R   +P  +I     + A T G A   DP+
Sbjct: 477 SSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPR 511



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 60/231 (25%), Positives = 74/231 (32%), Gaps = 86/231 (37%)

Query: 157 CQCHGHAARCAARARPPR-----------------CHCRHHTTGPGCESCRPSHRDWPWR 199
           C C+GHA  C       R                   C+HHTTG  CE C P     P  
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418

Query: 200 PATPRHPHPCLPCSC--------------------NQHARRCRFNSELFR---------- 229
           P     PH C  C+C                    N    RC   +E F           
Sbjct: 419 PLDS--PHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPS 476

Query: 230 --------------------LSGGRSGGVCER--------CRHHTAGRHCHYCQPGFWRD 261
                                + G  G  C +        C+ +  G HC  C PGF+  
Sbjct: 477 SSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGP 536

Query: 262 PSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
             QP         CQC   G     C+  +GQC C++G  G TC+RC PGY
Sbjct: 537 GCQP---------CQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGY 578



 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 48/138 (34%), Positives = 62/138 (44%), Gaps = 28/138 (20%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
           RC C+    GP C+ CRP +  +P           C  C+C+           L +L G 
Sbjct: 604 RCLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRGA-------LDQLCG- 645

Query: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
            +GG+C RCR    G  C  C PGF   PS        C  C C   G+    C+  SGQ
Sbjct: 646 -AGGLC-RCRPGYTGTACQECSPGFHGFPS--------CVPCHCSAEGSLHAACDPRSGQ 695

Query: 294 CTCKLGVTGLTCNRCGPG 311
           C+C+  VTGL C+ C PG
Sbjct: 696 CSCRPRVTGLRCDTCVPG 713



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 48/150 (32%), Positives = 60/150 (40%), Gaps = 16/150 (10%)

Query: 163  AARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCR 222
            A  C  R    +C C+    G  CE C P     P    +      C PC C+ +     
Sbjct: 1925 AEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSS-----CQPCDCSGNGDPNL 1979

Query: 223  FNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGA 282
              S+   L+G      C  C  HT G  C  C PGF+ +   P      C  C C P G 
Sbjct: 1980 LFSDCDPLTGA-----CRGCLRHTTGPRCEICAPGFYGNALLP----GNCTRCDCTPCGT 2030

Query: 283  TGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
                C+  SG C CK GVTG  C+RC  G+
Sbjct: 2031 E--ACDPHSGHCLCKAGVTGRRCDRCQEGH 2058



 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 49/147 (33%), Positives = 60/147 (40%), Gaps = 31/147 (21%)

Query: 175  CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
            C C     G  C+ C P      +R         C+PC C+ H+ RC   S         
Sbjct: 1831 CLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRCLPGS--------- 1877

Query: 235  SGGVCERCRHHTAGRHCHYCQPGFWR---DPSQPIFSRRACRACQCHPIG------ATGG 285
              GVC  C+H+T G HC  CQ GF     DPS P      C +C C P+       A G 
Sbjct: 1878 --GVCVDCQHNTEGAHCERCQAGFVSSRDDPSAP------CVSCPC-PLSVPSNNFAEGC 1928

Query: 286  TCNQTSGQCTCKLGVTGLTCNRCGPGY 312
                   QC CK G  G +C RC PG+
Sbjct: 1929 VLRGGRTQCLCKPGYAGASCERCAPGF 1955



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 82/289 (28%), Positives = 105/289 (36%), Gaps = 57/289 (19%)

Query: 37   AAVAASCPQACALS-PGNHLGARETCNGSLTLALGGPFLLTSVSLRFCTPG---PPALIL 92
            +A   SCP  C LS P N+        G  T  L  P      S   C PG    P ++ 
Sbjct: 1907 SAPCVSCP--CPLSVPSNNFAEGCVLRGGRTQCLCKPGY-AGASCERCAPGFFGNPLVLG 1963

Query: 93   SAAW-----ASGGPWRLLWHRPAWPGALGGPERVTFHSTPGPKATVAASHLRVEFGGQAG 147
            S+        +G P  L        GA  G  R     T GP+  + A      F G A 
Sbjct: 1964 SSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLR----HTTGPRCEICAPG----FYGNAL 2015

Query: 148  LAAAGLRGRCQCHGHAARCAARARPPR---CHCRHHTTGPGCESCRPSHRDWPWRPATPR 204
            L   G   RC C      C   A  P    C C+   TG  C+ C+  H  +        
Sbjct: 2016 LP--GNCTRCDC----TPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGG--- 2066

Query: 205  HPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQ 264
                C PC+C   A     + +          G C  CR  T G  C  C PG+W  P Q
Sbjct: 2067 ----CRPCACGPAAEGSECHPQ---------SGQCH-CRPGTMGPQCRECAPGYWGLPEQ 2112

Query: 265  PIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQ 313
                   CR CQC      GG C+  +G+C C  G++G  C+ C   +Q
Sbjct: 2113 ------GCRRCQC-----PGGRCDPHTGRCNCPPGLSGERCDTCSQQHQ 2150



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 56/194 (28%), Positives = 70/194 (36%), Gaps = 50/194 (25%)

Query: 144  GQAGLAAAGLRGRCQCHGHA-----ARCAA------RARP------------PRCHCRHH 180
            G  G       G+C CH H      +RCA         RP             +C C   
Sbjct: 1444 GATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPR 1503

Query: 181  TTGPGCESCRPSHRDWPWRPATPRHPHP---CLPCSCNQHARRCRFNSELFRLSGGRSGG 237
            T  P C  C+P               HP   C  C+C+    +     EL   +     G
Sbjct: 1504 TIPPDCLLCQPQTFGC----------HPLVGCEECNCSGPGIQ-----ELTDPTCDTDSG 1548

Query: 238  VCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCK 297
             C +CR +  GR C  C PGF   P         CR C CH  G   G C+  +GQC CK
Sbjct: 1549 QC-KCRPNVTGRRCDTCSPGFHGYPR--------CRPCDCHEAGTAPGVCDPLTGQCYCK 1599

Query: 298  LGVTGLTCNRCGPG 311
              V G  C++C  G
Sbjct: 1600 ENVQGPKCDQCSLG 1613



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 43/140 (30%), Positives = 58/140 (41%), Gaps = 31/140 (22%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
           C CR H  GP C+ C+P      W   +P +P  C  CSC+                 G 
Sbjct: 744 CMCRAHVEGPSCDRCKPGF----WG-LSPSNPEGCTRCSCDLR---------------GT 783

Query: 235 SGGVCER--------CRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT 286
            GGV E         C+ H  G+ C  C+ GF+       F    CR+C+C   GA G +
Sbjct: 784 LGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFG---CRSCRCDIGGALGQS 840

Query: 287 CNQTSGQCTCKLGVTGLTCN 306
           C   +G C C+    G TC+
Sbjct: 841 CEPRTGVCRCRPNTQGPTCS 860



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 50/166 (30%), Positives = 60/166 (36%), Gaps = 37/166 (22%)

Query: 157 CQCHGHAA-RCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHP------HPC 209
           C C    +   A   R  +C CR   TG  C++C P   ++P+  A   HP       P 
Sbjct: 677 CHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPA 736

Query: 210 LPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWR-DPSQPIFS 268
           LP                          V   CR H  G  C  C+PGFW   PS P   
Sbjct: 737 LP-----------------------EAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNP--- 770

Query: 269 RRACRACQCHPIGATGGT--CNQTSGQCTCKLGVTGLTCNRCGPGY 312
              C  C C   G  GG   C   +GQC CK  V G  C  C  G+
Sbjct: 771 -EGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGF 815



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 58/200 (29%), Positives = 73/200 (36%), Gaps = 37/200 (18%)

Query: 143 GGQAGLAAAGLRGR----CQCHGHAARCAARARPP--RCHCRHHTTGPGCESCRPSHRDW 196
           G    L A G  G     CQC         R  P   +C CR    G  C+ C P +  +
Sbjct: 523 GTHCELCAPGFYGPGCQPCQCSSPGV-ADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHF 581

Query: 197 PWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQP 256
           P        P   LP  C++ A RC                    C+   AG HC  C+P
Sbjct: 582 PLCQLCGCSPAGTLPEGCDE-AGRCL-------------------CQPEFAGPHCDRCRP 621

Query: 257 GFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSR 316
           G+   P+        C+AC C P GA    C    G C C+ G TG  C  C PG+    
Sbjct: 622 GYHGFPN--------CQACTCDPRGALDQLCG-AGGLCRCRPGYTGTACQECSPGFHGFP 672

Query: 317 SPRMPCQRIPEATTTLATTP 336
           S  +PC    E +   A  P
Sbjct: 673 S-CVPCHCSAEGSLHAACDP 691



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 47/151 (31%), Positives = 55/151 (36%), Gaps = 31/151 (20%)

Query: 177  CRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC---SCNQHARRCRFNSELFRLSGG 233
            C  HTTGP CE C P        P        C PC   +C+ H+  C            
Sbjct: 1994 CLRHTTGPRCEICAPGFYGNALLPGNCTRCD-CTPCGTEACDPHSGHCL----------- 2041

Query: 234  RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
                    C+    GR C  CQ G +            CR C C P  A G  C+  SGQ
Sbjct: 2042 --------CKAGVTGRRCDRCQEGHFG-----FDGCGGCRPCACGP-AAEGSECHPQSGQ 2087

Query: 294  CTCKLGVTGLTCNRCGPGYQQSRSPRMPCQR 324
            C C+ G  G  C  C PGY     P   C+R
Sbjct: 2088 CHCRPGTMGPQCRECAPGYW--GLPEQGCRR 2116



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 44/142 (30%), Positives = 53/142 (37%), Gaps = 32/142 (22%)

Query: 174  RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
            +C C  H  G  C  C   +  +P           C PC C   AR C    EL      
Sbjct: 1456 QCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCG--ARLC---DELT----- 1495

Query: 234  RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGA---TGGTCNQT 290
               G C  C   T    C  CQP  +     P+     C  C C   G    T  TC+  
Sbjct: 1496 ---GQCI-CPPRTIPPDCLLCQPQTFG--CHPLVG---CEECNCSGPGIQELTDPTCDTD 1546

Query: 291  SGQCTCKLGVTGLTCNRCGPGY 312
            SGQC C+  VTG  C+ C PG+
Sbjct: 1547 SGQCKCRPNVTGRRCDTCSPGF 1568



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 23/50 (46%), Positives = 26/50 (52%)

Query: 263  SQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
            S  +F     R C CH +GATG TC    GQC C   V G  C+RC  GY
Sbjct: 1426 SLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGY 1475



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 40/137 (29%), Positives = 50/137 (36%), Gaps = 41/137 (29%)

Query: 236  GGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCT 295
            GG C  C  H  GR C  C  G+W  P+        CR C C   GA    C++ +GQC 
Sbjct: 1454 GGQCP-CHAHVIGRDCSRCATGYWGFPN--------CRPCDC---GAR--LCDELTGQCI 1499

Query: 296  CK---------------LGVTGLT----CNRCGPGYQQSRSPRM-----PCQRIPEATTT 331
            C                 G   L     CN  GPG Q+   P        C+  P  T  
Sbjct: 1500 CPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGR 1559

Query: 332  LATT--PGAYSSDPQCQ 346
               T  PG +   P+C+
Sbjct: 1560 RCDTCSPG-FHGYPRCR 1575



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 11/89 (12%)

Query: 143  GGQAGLAAAGLRG--RCQ-CHGHAARCAARARPP---RCHCRHHTTGPGCESCRPSHRDW 196
            G +    + G  G  RC+ C  H A  A     P   +C+C+ +  GP C+ C  S   +
Sbjct: 1558 GRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQC--SLGTF 1615

Query: 197  PWRPATPRHPHPCLPCSCNQHARRCRFNS 225
                A P+    C  C C     RCR +S
Sbjct: 1616 SLDAANPKG---CTRCFCFGATERCRSSS 1641


>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
          Length = 3333

 Score =  125 bits (315), Expect = 7e-29
 Identities = 64/181 (35%), Positives = 84/181 (46%), Gaps = 15/181 (8%)

Query: 155 GRCQCHGHAARCAARARPP--RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC 212
           G+C C+GHA  C         RC C+HHT G  C+ C   +    WRPA     H C  C
Sbjct: 297 GQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEAC 356

Query: 213 SCNQHARRCRFNSELFRLSGG-------RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQP 265
           +C+ HA  C ++ ++ R             GGVC  C+H+TAG +C  C  G++R    P
Sbjct: 357 NCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP 416

Query: 266 IFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRI 325
           + +   C  C C P  A G  C Q SG+C CK    G  C +C  GY         C RI
Sbjct: 417 VDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPF----CLRI 470

Query: 326 P 326
           P
Sbjct: 471 P 471



 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 48/140 (34%), Positives = 66/140 (47%), Gaps = 22/140 (15%)

Query: 175  CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
            C C     G  C+ C P +    +R     +   C+PC+CN H+ +C+  S         
Sbjct: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQDGS--------- 1700

Query: 235  SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIG--ATGGTCNQTSG 292
              G+C  C+H+TAG HC  CQ G++ +         +CRAC C      ATG   N    
Sbjct: 1701 --GICVNCQHNTAGEHCERCQEGYYGNAVHG-----SCRACPCPHTNSFATGCVVNGGDV 1753

Query: 293  QCTCKLGVTGLTCNRCGPGY 312
            +C+CK G TG  C RC PGY
Sbjct: 1754 RCSCKAGYTGTQCERCAPGY 1773



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 51/168 (30%), Positives = 63/168 (37%), Gaps = 34/168 (20%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWP-----WRPATPRHPHPCLP----CSCN-----QHAR 219
           RC CR    GP C++CR     +P     W  A   +  PC      C C      Q   
Sbjct: 508 RCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCD 567

Query: 220 RCRFNSELFRLSGGRSG------------GVCERCRHHTAGRHCHYCQPGFWR-DPSQPI 266
           RC   +  F    G S             G C+ C+ H  G  C  C+  +W  D   P 
Sbjct: 568 RCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ-CKLHVEGPTCSRCKLLYWNLDKENP- 625

Query: 267 FSRRACRACQCHPIGATGGT--CNQTSGQCTCKLGVTGLTCNRCGPGY 312
                C  C+CH  G   GT  C Q  G C CK  V G +C+ C  GY
Sbjct: 626 ---SGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGY 670



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 50/159 (31%), Positives = 69/159 (43%), Gaps = 16/159 (10%)

Query: 157 CQCHG-HAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
           C C   HA  C   +   RCHC+ +  G  CE C   + ++P+    P  P    P S +
Sbjct: 426 CSCDPEHADGCEQGSG--RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFP-VSTPSSED 482

Query: 216 QHA---RRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRAC 272
             A   + C  N E        + G C  CR    G  C  C+ GF+  P         C
Sbjct: 483 PVAGDIKGCDCNLEGVLPEICDAHGRC-LCRPGVEGPRCDTCRSGFYSFP--------IC 533

Query: 273 RACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPG 311
           +AC C  +G+    C+  +GQC C+ GVTG  C+RC  G
Sbjct: 534 QACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 43/139 (30%), Positives = 53/139 (38%), Gaps = 23/139 (16%)

Query: 174  RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP-CLPCSCNQHARRCRFNSELFRLSG 232
            +C C   T  P CE C      +        HP   C  C+C++     R   E      
Sbjct: 1325 QCRCPPRTVRPQCEVCETHSFSF--------HPMAGCEGCNCSR-----RGTIEAAMPEC 1371

Query: 233  GRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSG 292
             R  G C RC+    GR C  C  GF+R P         C  C C+  G   G C+  +G
Sbjct: 1372 DRDSGQC-RCKPRITGRQCDRCASGFYRFPE--------CVPCNCNRDGTEPGVCDPGTG 1422

Query: 293  QCTCKLGVTGLTCNRCGPG 311
             C CK  V G  CN C  G
Sbjct: 1423 ACLCKENVEGTECNVCREG 1441



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 41/158 (25%), Positives = 58/158 (36%), Gaps = 29/158 (18%)

Query: 159 CHGHAARC----AARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC 214
           C G ++ C       +    C C+ H  GP C  C+  +    W      +P  C  C C
Sbjct: 579 CQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLY----WN-LDKENPSGCSECKC 633

Query: 215 NQHAR-----RCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSR 269
           ++         CR           +  G C  C+ H  G  C  C+ G++       F  
Sbjct: 634 HKAGTVSGTGECR-----------QGDGDCH-CKSHVGGDSCDTCEDGYFALEKSNYFG- 680

Query: 270 RACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNR 307
             C+ CQC   GA    C+  SG C C+  V G  C R
Sbjct: 681 --CQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR 716



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 52/188 (27%), Positives = 67/188 (35%), Gaps = 40/188 (21%)

Query: 157  CQCHGHAA---RCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCS 213
            C+CH   A    C+      +C C+ +  G  C  C   H  +P           C PCS
Sbjct: 1266 CECHPTGATGPHCSPEGG--QCPCQPNVIGRQCTRCATGHYGFP----------RCKPCS 1313

Query: 214  CNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACR 273
            C +  R C               G C RC   T    C  C+       S        C 
Sbjct: 1314 CGR--RLCE-----------EMTGQC-RCPPRTVRPQCEVCETH-----SFSFHPMAGCE 1354

Query: 274  ACQCHPIG---ATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPR-MPCQRIPEAT 329
             C C   G   A    C++ SGQC CK  +TG  C+RC  G+   R P  +PC    + T
Sbjct: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFY--RFPECVPCNCNRDGT 1412

Query: 330  TTLATTPG 337
                  PG
Sbjct: 1413 EPGVCDPG 1420



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 7/84 (8%)

Query: 267  FSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPR-MPC--- 322
            F  +    C+CHP GATG  C+   GQC C+  V G  C RC  G+     PR  PC   
Sbjct: 1258 FYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY--GFPRCKPCSCG 1315

Query: 323  QRIPEATTTLATTPGAYSSDPQCQ 346
            +R+ E  T     P   +  PQC+
Sbjct: 1316 RRLCEEMTGQCRCP-PRTVRPQCE 1338



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 37/141 (26%), Positives = 56/141 (39%), Gaps = 25/141 (17%)

Query: 157  CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC-- 214
            C C+GH+ +C         +C+H+T G  CE C+  +           H   C  C C  
Sbjct: 1687 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYY------GNAVH-GSCRACPCPH 1738

Query: 215  -NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACR 273
             N  A  C  N           G V   C+    G  C  C PG++ +P +      +C+
Sbjct: 1739 TNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYFGNPQK---FGGSCQ 1785

Query: 274  ACQCHPIGATGGTCNQTSGQC 294
             C C+  G   G+C+  +G C
Sbjct: 1786 PCSCNSNGQL-GSCHPLTGDC 1805



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 24/79 (30%), Positives = 30/79 (37%), Gaps = 8/79 (10%)

Query: 144  GQAGLAAAGLRGRCQC---HGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRP 200
            G  G A  G    C C   +  A  C       RC C+   TG  CE C P +   P   
Sbjct: 1721 GYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP--- 1777

Query: 201  ATPRHPHPCLPCSCNQHAR 219
               +    C PCSCN + +
Sbjct: 1778 --QKFGGSCQPCSCNSNGQ 1794


>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
          Length = 3277

 Score =  125 bits (315), Expect = 7e-29
 Identities = 64/181 (35%), Positives = 84/181 (46%), Gaps = 15/181 (8%)

Query: 155 GRCQCHGHAARCAARARPP--RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC 212
           G+C C+GHA  C         RC C+HHT G  C+ C   +    WRPA     H C  C
Sbjct: 297 GQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEAC 356

Query: 213 SCNQHARRCRFNSELFRLSGG-------RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQP 265
           +C+ HA  C ++ ++ R             GGVC  C+H+TAG +C  C  G++R    P
Sbjct: 357 NCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP 416

Query: 266 IFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRI 325
           + +   C  C C P  A G  C Q SG+C CK    G  C +C  GY         C RI
Sbjct: 417 VDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPF----CLRI 470

Query: 326 P 326
           P
Sbjct: 471 P 471



 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 48/140 (34%), Positives = 66/140 (47%), Gaps = 22/140 (15%)

Query: 175  CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
            C C     G  C+ C P +    +R     +   C+PC+CN H+ +C+  S         
Sbjct: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQDGS--------- 1700

Query: 235  SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIG--ATGGTCNQTSG 292
              G+C  C+H+TAG HC  CQ G++ +         +CRAC C      ATG   N    
Sbjct: 1701 --GICVNCQHNTAGEHCERCQEGYYGNAVHG-----SCRACPCPHTNSFATGCVVNGGDV 1753

Query: 293  QCTCKLGVTGLTCNRCGPGY 312
            +C+CK G TG  C RC PGY
Sbjct: 1754 RCSCKAGYTGTQCERCAPGY 1773



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 51/168 (30%), Positives = 63/168 (37%), Gaps = 34/168 (20%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWP-----WRPATPRHPHPCLP----CSCN-----QHAR 219
           RC CR    GP C++CR     +P     W  A   +  PC      C C      Q   
Sbjct: 508 RCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCD 567

Query: 220 RCRFNSELFRLSGGRSG------------GVCERCRHHTAGRHCHYCQPGFWR-DPSQPI 266
           RC   +  F    G S             G C+ C+ H  G  C  C+  +W  D   P 
Sbjct: 568 RCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ-CKLHVEGPTCSRCKLLYWNLDKENP- 625

Query: 267 FSRRACRACQCHPIGATGGT--CNQTSGQCTCKLGVTGLTCNRCGPGY 312
                C  C+CH  G   GT  C Q  G C CK  V G +C+ C  GY
Sbjct: 626 ---SGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGY 670



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 50/159 (31%), Positives = 69/159 (43%), Gaps = 16/159 (10%)

Query: 157 CQCHG-HAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
           C C   HA  C   +   RCHC+ +  G  CE C   + ++P+    P  P    P S +
Sbjct: 426 CSCDPEHADGCEQGSG--RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFP-VSTPSSED 482

Query: 216 QHA---RRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRAC 272
             A   + C  N E        + G C  CR    G  C  C+ GF+  P         C
Sbjct: 483 PVAGDIKGCDCNLEGVLPEICDAHGRC-LCRPGVEGPRCDTCRSGFYSFP--------IC 533

Query: 273 RACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPG 311
           +AC C  +G+    C+  +GQC C+ GVTG  C+RC  G
Sbjct: 534 QACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 43/139 (30%), Positives = 53/139 (38%), Gaps = 23/139 (16%)

Query: 174  RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP-CLPCSCNQHARRCRFNSELFRLSG 232
            +C C   T  P CE C      +        HP   C  C+C++     R   E      
Sbjct: 1325 QCRCPPRTVRPQCEVCETHSFSF--------HPMAGCEGCNCSR-----RGTIEAAMPEC 1371

Query: 233  GRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSG 292
             R  G C RC+    GR C  C  GF+R P         C  C C+  G   G C+  +G
Sbjct: 1372 DRDSGQC-RCKPRITGRQCDRCASGFYRFPE--------CVPCNCNRDGTEPGVCDPGTG 1422

Query: 293  QCTCKLGVTGLTCNRCGPG 311
             C CK  V G  CN C  G
Sbjct: 1423 ACLCKENVEGTECNVCREG 1441



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 41/158 (25%), Positives = 58/158 (36%), Gaps = 29/158 (18%)

Query: 159 CHGHAARC----AARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC 214
           C G ++ C       +    C C+ H  GP C  C+  +    W      +P  C  C C
Sbjct: 579 CQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLY----WN-LDKENPSGCSECKC 633

Query: 215 NQHAR-----RCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSR 269
           ++         CR           +  G C  C+ H  G  C  C+ G++       F  
Sbjct: 634 HKAGTVSGTGECR-----------QGDGDCH-CKSHVGGDSCDTCEDGYFALEKSNYFG- 680

Query: 270 RACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNR 307
             C+ CQC   GA    C+  SG C C+  V G  C R
Sbjct: 681 --CQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR 716



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 52/188 (27%), Positives = 67/188 (35%), Gaps = 40/188 (21%)

Query: 157  CQCHGHAA---RCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCS 213
            C+CH   A    C+      +C C+ +  G  C  C   H  +P           C PCS
Sbjct: 1266 CECHPTGATGPHCSPEGG--QCPCQPNVIGRQCTRCATGHYGFP----------RCKPCS 1313

Query: 214  CNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACR 273
            C +  R C               G C RC   T    C  C+       S        C 
Sbjct: 1314 CGR--RLCE-----------EMTGQC-RCPPRTVRPQCEVCETH-----SFSFHPMAGCE 1354

Query: 274  ACQCHPIG---ATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPR-MPCQRIPEAT 329
             C C   G   A    C++ SGQC CK  +TG  C+RC  G+   R P  +PC    + T
Sbjct: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFY--RFPECVPCNCNRDGT 1412

Query: 330  TTLATTPG 337
                  PG
Sbjct: 1413 EPGVCDPG 1420



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 31/84 (36%), Positives = 40/84 (47%), Gaps = 7/84 (8%)

Query: 267  FSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPR-MPC--- 322
            F  +    C+CHP GATG  C+   GQC C+  V G  C RC  G+     PR  PC   
Sbjct: 1258 FYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY--GFPRCKPCSCG 1315

Query: 323  QRIPEATTTLATTPGAYSSDPQCQ 346
            +R+ E  T     P   +  PQC+
Sbjct: 1316 RRLCEEMTGQCRCP-PRTVRPQCE 1338



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 37/141 (26%), Positives = 56/141 (39%), Gaps = 25/141 (17%)

Query: 157  CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC-- 214
            C C+GH+ +C         +C+H+T G  CE C+  +           H   C  C C  
Sbjct: 1687 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYY------GNAVH-GSCRACPCPH 1738

Query: 215  -NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACR 273
             N  A  C  N           G V   C+    G  C  C PG++ +P +      +C+
Sbjct: 1739 TNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYFGNPQK---FGGSCQ 1785

Query: 274  ACQCHPIGATGGTCNQTSGQC 294
             C C+  G   G+C+  +G C
Sbjct: 1786 PCSCNSNGQL-GSCHPLTGDC 1805



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 24/79 (30%), Positives = 30/79 (37%), Gaps = 8/79 (10%)

Query: 144  GQAGLAAAGLRGRCQC---HGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRP 200
            G  G A  G    C C   +  A  C       RC C+   TG  CE C P +   P   
Sbjct: 1721 GYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP--- 1777

Query: 201  ATPRHPHPCLPCSCNQHAR 219
               +    C PCSCN + +
Sbjct: 1778 --QKFGGSCQPCSCNSNGQ 1794


>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
          Length = 539

 Score =  122 bits (307), Expect = 6e-28
 Identities = 59/171 (34%), Positives = 87/171 (50%), Gaps = 20/171 (11%)

Query: 153 LRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPAT----PR-HPH 207
           +RGRC+C+ HA  C        C C H+TTGP C  C+ +++  PW P +    P+   +
Sbjct: 293 VRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN 352

Query: 208 PCLP-------CSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWR 260
            C+P       C C  H+ RC +   L  +       +C  C+H+T G+HC  C+ G++R
Sbjct: 353 TCIPSISSIGNCECFGHSNRCSYIDLLNTV-------ICVSCKHNTRGQHCELCRLGYFR 405

Query: 261 DPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPG 311
           + S  +     C  C C+P+G+    CN  SG C CK G TG  C+ C PG
Sbjct: 406 NASAQLDDENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPG 455



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 21/79 (26%), Positives = 31/79 (39%), Gaps = 15/79 (18%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCR-----FNSELFR 229
           C C+  TTGP C+ C P +    W        + C P  C+     C+      N+    
Sbjct: 438 CECKTGTTGPKCDECLPGN---SWH-------YGCQPNVCDNELLHCQNGGTCHNNVRCL 487

Query: 230 LSGGRSGGVCERCRHHTAG 248
                +G +CE+ R   AG
Sbjct: 488 CPAAYTGILCEKLRCEEAG 506



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 11/102 (10%)

Query: 275 CQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLAT 334
           C+C+ + AT    + +   C C+   TG  C +C   YQ    P  P   +P    T  T
Sbjct: 297 CKCN-LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQ--GRPWSPGSYLPIPKGTANT 353

Query: 335 TPGAYSSDPQCQ--------NYCNMSDTRVHMSLRRYCQQDH 368
              + SS   C+        +Y ++ +T + +S +   +  H
Sbjct: 354 CIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQH 395


>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
          Length = 3075

 Score =  122 bits (305), Expect = 1e-27
 Identities = 57/179 (31%), Positives = 81/179 (45%), Gaps = 20/179 (11%)

Query: 155 GRCQCHGHAARCA--ARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC 212
           G C C+GHA+ C      +  +C C H+T G  C  C P +   PWRP T    + C  C
Sbjct: 268 GMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEAC 327

Query: 213 SCNQHARRCRFNSELFRLSGG-------RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQP 265
           +C+  A+ C ++  + +           R GGVC  C  +T G +C  C  G++R     
Sbjct: 328 NCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVS 387

Query: 266 IFSRRACRACQCHPIGATGGTC-----------NQTSGQCTCKLGVTGLTCNRCGPGYQ 313
            +    CR C C P+G+    C            +  GQC CK G TG  C+RC  GY+
Sbjct: 388 PYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYK 446



 Score = 92.4 bits (228), Expect = 8e-19
 Identities = 63/218 (28%), Positives = 80/218 (36%), Gaps = 62/218 (28%)

Query: 147 GLAAAGLRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHP 206
           G+   G+   C+CHGHAA C          C H+TTG  CE C P     P R      P
Sbjct: 732 GILFGGICQPCECHGHAAECNVHG--VCIACAHNTTGVHCEQCLPGFYGEPSRGT----P 785

Query: 207 HPCLPCSC------NQHARRCRFNSE----LFRLSGGRSGGVCERCRH------------ 244
             C PC+C      N  +  C  N          + G SG  CERC              
Sbjct: 786 GDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGES 845

Query: 245 ------------------------------HTAGRHCHYCQPGFWRDPSQPIFSRRACRA 274
                                         +T G HC  C  GF+ D      + + CRA
Sbjct: 846 CVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDA----VTAKNCRA 901

Query: 275 CQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
           C+CH  G+    C+  +G C CK  VTG  C++C  GY
Sbjct: 902 CECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGY 939



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 49/186 (26%), Positives = 70/186 (37%), Gaps = 53/186 (28%)

Query: 175  CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP----CLPCSCNQHARRCRFNSELFRL 230
            C C   T G  C+ C P +        + R P P    C+PCSCN H+  C  N+     
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421

Query: 231  SGGRSGG----------------------------------------------VCERCRH 244
             G  + G                                               C+ C  
Sbjct: 1422 CGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLL 1481

Query: 245  HTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLT 304
               G+HC  C   ++ +P  P     +C+ C C+P G+  G C++TSGQC C+LG +GL 
Sbjct: 1482 GYEGKHCERCSSSYYGNPQTP---GGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538

Query: 305  CNRCGP 310
            C+ C P
Sbjct: 1539 CDECEP 1544



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 47/145 (32%), Positives = 60/145 (41%), Gaps = 25/145 (17%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
           C C    TG  CESC   +    +R         C PC C+ HA  C  +          
Sbjct: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754

Query: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGG---TCNQTS 291
             GVC  C H+T G HC  C PGF+ +PS+   +   C+ C C    A+     TC+   
Sbjct: 755 --GVCIACAHNTTGVHCEQCLPGFYGEPSRG--TPGDCQPCACPLTIASNNFSPTCHLND 810

Query: 292 GQ---CT-CKLGVTGLTCNRCGPGY 312
           G    C  C  G +G  C RC  GY
Sbjct: 811 GDEVVCDWCAPGYSGAWCERCADGY 835



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 47/196 (23%), Positives = 71/196 (36%), Gaps = 54/196 (27%)

Query: 157  CQCH---GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCS 213
            C+CH    H+A C        C C+ + TG  C+ C   +             H C PC+
Sbjct: 902  CECHVKGSHSAVC--HLETGLCDCKPNVTGQQCDQCLHGYYGLD-------SGHGCRPCN 952

Query: 214  CN---QHARRCRFNSELFRLSGGRSGGVCERCRH-------------------------- 244
            C+     +  C    +   + G  +G  C+RC H                          
Sbjct: 953  CSVAGSVSDGCTDEGQCHCVPGV-AGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPET 1011

Query: 245  -------HTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCK 297
                   HT G  C  C+ G W   ++       C+AC C  +G+T   C+  +G C CK
Sbjct: 1012 GECVCPPHTQGVKCEECEDGHWGYDAEV-----GCQACNCSLVGSTHHRCDVVTGHCQCK 1066

Query: 298  LGVTGLTCNRCGPGYQ 313
                G  C++C  GY+
Sbjct: 1067 SKFGGRACDQCSLGYR 1082



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 41/149 (27%), Positives = 51/149 (34%), Gaps = 39/149 (26%)

Query: 175  CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN---QHARRCRFNSELFRLS 231
            C C  HT G  CE C   H  W +          C  C+C+       RC   +      
Sbjct: 1014 CVCPPHTQGVKCEECEDGH--WGYDAEVG-----CQACNCSLVGSTHHRCDVVT------ 1060

Query: 232  GGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCN--- 288
                 G C+ C+    GR C  C  G+   P         C  C C   G +G  CN   
Sbjct: 1061 -----GHCQ-CKSKFGGRACDQCSLGYRDFPD--------CVPCDCDLRGTSGDACNLEQ 1106

Query: 289  ------QTSGQCTCKLGVTGLTCNRCGPG 311
                  + +G C CK  V G  CN C  G
Sbjct: 1107 GLCGCVEETGACPCKENVFGPQCNECREG 1135



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 37/151 (24%), Positives = 58/151 (38%), Gaps = 26/151 (17%)

Query: 171 RPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRL 230
           +P +C C+   TG  C+ C+  ++D+P           C+ C CN           +   
Sbjct: 423 QPGQCPCKEGYTGEKCDRCQLGYKDYP----------TCVSCGCN----------PVGSA 462

Query: 231 SGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQT 290
           S     G C  C+ +  G+ C  C+PGF+    +   + R C  C C  +     + +  
Sbjct: 463 SDEPCTGPCV-CKENVEGKACDRCKPGFYNLKEK---NPRGCSECFCFGVSDVCSSLSWP 518

Query: 291 SGQCTCKLG--VTGLTCNRCGPGYQQSRSPR 319
            GQ     G  VT L   R  P  Q +   R
Sbjct: 519 VGQVNSMSGWLVTDLISPRKIPSQQDALGGR 549



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 8/87 (9%)

Query: 239 CERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKL 298
           CE C     G  C  C  G++R     I     C+ C+CH   A    CN       C  
Sbjct: 709 CE-CPQGYTGTSCESCLSGYYRVDG--ILFGGICQPCECHGHAAE---CNVHGVCIACAH 762

Query: 299 GVTGLTCNRCGPGY--QQSRSPRMPCQ 323
             TG+ C +C PG+  + SR     CQ
Sbjct: 763 NTTGVHCEQCLPGFYGEPSRGTPGDCQ 789



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 12/22 (54%), Positives = 14/22 (63%)

Query: 293 QCTCKLGVTGLTCNRCGPGYQQ 314
           QC C+    G +CNRC PGY Q
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQ 310



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 10/25 (40%), Positives = 13/25 (52%)

Query: 294  CTCKLGVTGLTCNRCGPGYQQSRSP 318
            C C  G  G +C  C PGY + + P
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLP 1386



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 15/63 (23%), Positives = 21/63 (33%), Gaps = 5/63 (7%)

Query: 159  CHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHA 218
            C+     C        C C+ +  GP C  CR              +P  C PC C+  +
Sbjct: 1102 CNLEQGLCGCVEETGACPCKENVFGPQCNECREG-----TFALRADNPLGCSPCFCSGLS 1156

Query: 219  RRC 221
              C
Sbjct: 1157 HLC 1159


>gi|190014607 netrin G2 [Homo sapiens]
          Length = 530

 Score =  115 bits (287), Expect = 1e-25
 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 19/167 (11%)

Query: 155 GRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWR-----PATPRHPHPC 209
           GRC+C+ HA  C+ R    +C C H+TTGP C  C+ + R   WR     P     P+ C
Sbjct: 285 GRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344

Query: 210 LP------CSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPS 263
                   C C  H+ RC +   L  ++       C  C+H+T G+HC +C+ G++R+ S
Sbjct: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397

Query: 264 QPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGP 310
             +     C  C C+ IG+    CN+T G C C+ G  G  C+ C P
Sbjct: 398 AELDDENVCIECNCNQIGSVHDRCNET-GFCECREGAAGPKCDDCLP 443



 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 70/234 (29%), Positives = 91/234 (38%), Gaps = 45/234 (19%)

Query: 124 HSTPGP-----------KATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCA--ARA 170
           H+T GP           ++  A S+L +  G     A AG  G C+C+GH+ RC+     
Sbjct: 309 HNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFL 368

Query: 171 RPPRC-HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHAR---RCRFNSE 226
               C  C+H+T G  C+ CR  +  +    A     + C+ C+CNQ      RC     
Sbjct: 369 NVVTCVSCKHNTRGQHCQHCRLGY--YRNGSAELDDENVCIECNCNQIGSVHDRC----- 421

Query: 227 LFRLSGGRSGGVCERCRHHTAGRHCHYCQP-GFWRDPSQPIFSRRACRACQCHPIGATGG 285
                     G CE CR   AG  C  C P  +WR    P         CQ       GG
Sbjct: 422 -------NETGFCE-CREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ------NGG 467

Query: 286 TCNQTSGQCTCKLGVTGLTCN--RCGPGYQQSRSPRMPCQRIPEATTTLATTPG 337
           TC Q   +C C  G TG+ C   RC P         + C R P A    AT  G
Sbjct: 468 TCLQNQ-RCACPRGYTGVRCEQPRCDPADDDG---GLDCDRAPGAAPRPATLLG 517


>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
           sapiens]
          Length = 3118

 Score =  114 bits (286), Expect = 2e-25
 Identities = 59/176 (33%), Positives = 77/176 (43%), Gaps = 18/176 (10%)

Query: 155 GRCQCHGHAARCAA--RARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC 212
           G C C+GHA  C         RC C H+T G  C+ C P     PWR  T      C  C
Sbjct: 285 GMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEAC 344

Query: 213 SCNQHARRCRFNSELFRLS-----GGR--SGGVCERCRHHTAGRHCHYCQPGFWRDPSQP 265
           +C+  A  C ++  + R +      G+   GGVC  C  +TAG +C  C  GF+R     
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404

Query: 266 IFSRRACRACQCHPIGATGGTC---------NQTSGQCTCKLGVTGLTCNRCGPGY 312
               R C+ C C PIG+    C             G C CK G  G++C+RC  GY
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 50/171 (29%), Positives = 75/171 (43%), Gaps = 11/171 (6%)

Query: 138  LRVEFGGQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWP 197
            LR + GG+      G    CQC+GH++ C       + +C+HHT G  CE C   +    
Sbjct: 1401 LRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ-NCQHHTAGDFCERCALGYYG-- 1457

Query: 198  WRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPG 257
                    P+ C  C+C   +    F+     ++ G     C  C     G++C  C PG
Sbjct: 1458 ---IVKGLPNDCQQCACPLISSSNNFSPSC--VAEGLDDYRCTACPRGYEGQYCERCAPG 1512

Query: 258  FWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRC 308
            +   P  P  S   C+ C+C P G+    C+  +G CTC+ G TG  C+ C
Sbjct: 1513 YTGSPGNPGGS---CQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560



 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 56/186 (30%), Positives = 73/186 (39%), Gaps = 25/186 (13%)

Query: 147 GLAAAGLRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHP 206
           G    G+   CQC GHA  C         +C+ HT GP C+ C P     P    T    
Sbjct: 747 GTIFGGICEPCQCFGHAESC-DDVTGECLNCKDHTGGPYCDKCLPGFYGEP----TKGTS 801

Query: 207 HPCLPCSC------NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWR 260
             C PC+C      N  +  C  +  L        G +C+ C     G  C  C  G++ 
Sbjct: 802 EDCQPCACPLNIPSNNFSPTCHLDRSL--------GLICDGCPVGYTGPRCERCAEGYFG 853

Query: 261 DPSQPIFSRRACRACQCHP--IGATGGTCNQTSGQC-TCKLGVTGLTCNRCGPGYQQSRS 317
            PS P     +C+ CQC+     +  G+C+  SG C  CK G TG  C  C  GY     
Sbjct: 854 QPSVP---GGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV 910

Query: 318 PRMPCQ 323
               CQ
Sbjct: 911 DAKNCQ 916



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 29/179 (16%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
           C C    TG  CESC P HR    R         C PC C  HA  C   +         
Sbjct: 724 CQCPPGYTGSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCDDVT--------- 770

Query: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
             G C  C+ HT G +C  C PGF+ +P++   +   C+ C C P+       +      
Sbjct: 771 --GECLNCKDHTGGPYCDKCLPGFYGEPTKG--TSEDCQPCAC-PLNIPSNNFSP----- 820

Query: 295 TCKLGVT-GLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMS 352
           TC L  + GL C+ C  GY   R     C+R  E      + PG      QC +  + S
Sbjct: 821 TCHLDRSLGLICDGCPVGYTGPR-----CERCAEGYFGQPSVPGGSCQPCQCNDNLDFS 874



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 47/162 (29%), Positives = 64/162 (39%), Gaps = 27/162 (16%)

Query: 174  RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP----CLPCSCNQHARRCRFNSELFR 229
            +C C    +G  CE+C P       +P   R P P    C+PC CN H+  C   +    
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGG-RTPGPTLGTCVPCQCNGHSSLCDPETS--- 1434

Query: 230  LSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQ 289
                    +C+ C+HHTAG  C  C  G++            C+ C C  I ++      
Sbjct: 1435 --------ICQNCQHHTAGDFCERCALGYYGIVKG---LPNDCQQCACPLISSSNNFSPS 1483

Query: 290  TSGQ------CT-CKLGVTGLTCNRCGPGYQQS-RSPRMPCQ 323
               +      CT C  G  G  C RC PGY  S  +P   CQ
Sbjct: 1484 CVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ 1525



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 52/240 (21%), Positives = 84/240 (35%), Gaps = 52/240 (21%)

Query: 157  CQCH-GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
            C+C+ G +      ++  +C CR +  G  C+ C+             +    C+PC+CN
Sbjct: 918  CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL-------QSARGCVPCNCN 970

Query: 216  QHARR---CRFNSELFRLSGGRSGGVCERCRH---------------------------- 244
                +   C  + + +    G +G  C+RC H                            
Sbjct: 971  SFGSKSFDCEESGQCW-CQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGR 1029

Query: 245  -----HTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLG 299
                 +T G  C  C P  W            C+AC C  +G+    CN  +GQC C   
Sbjct: 1030 CICPPNTIGEKCSKCAPNTWGHSITT-----GCKACNCSTVGSLDFQCNVNTGQCNCHPK 1084

Query: 300  VTGLTCNRCGPGYQQSRSPRMPCQRIP--EATTTLATTPGAYSSDPQCQNYCNMSDTRVH 357
             +G  C  C  G+       +    +P  +ATT  + T     SD   Q  C ++   +H
Sbjct: 1085 FSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIH 1144



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 46/167 (27%), Positives = 60/167 (35%), Gaps = 41/167 (24%)

Query: 157  CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
            C+C      C  +    RC C  +T G  C  C P+   W     T      C  C+C+ 
Sbjct: 1014 CECSHLGNNCDPKTG--RCICPPNTIGEKCSKCAPN--TWGHSITTG-----CKACNCST 1064

Query: 217  HAR---RCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACR 273
                  +C  N+           G C  C    +G  C  C  G W  P         C 
Sbjct: 1065 VGSLDFQCNVNT-----------GQCN-CHPKFSGAKCTECSRGHWNYPR--------CN 1104

Query: 274  ACQCHPIGATGGTCNQTS---------GQCTCKLGVTGLTCNRCGPG 311
             C C   G    TC+  +         GQCTCK+ V G+ C+RC PG
Sbjct: 1105 LCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPG 1151



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 42/186 (22%), Positives = 58/186 (31%), Gaps = 74/186 (39%)

Query: 157 CQCHGHAARCAARARPPR-----------------CHCRHHTTGPGCESCRPSHRDWPWR 199
           C CHG A  C       R                  +C  +T G  CE+C     D  +R
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCT----DGFFR 399

Query: 200 P--ATPRHPHPCLPCSCN-------------QHARRCRFNSELFRLSGGRSGGV-CERC- 242
           P   +P +P PC PC C+             +HARR          +G   GGV C+RC 
Sbjct: 400 PKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTG--FGGVSCDRCA 457

Query: 243 -------------------------------RHHTAGRHCHYCQPGFWRDPSQPIFSRRA 271
                                          + +  G  C  C+ GF+        + + 
Sbjct: 458 RGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQED---NWKG 514

Query: 272 CRACQC 277
           C  C C
Sbjct: 515 CDECFC 520



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 24/62 (38%), Positives = 32/62 (51%), Gaps = 9/62 (14%)

Query: 293  QCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEAT--TTLATTPGAYSS--DPQ---C 345
            +C C LG +GL+C  C PG+ + RS   P  R P  T  T +      +SS  DP+   C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRS--QPGGRTPGPTLGTCVPCQCNGHSSLCDPETSIC 1436

Query: 346  QN 347
            QN
Sbjct: 1437 QN 1438


>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
           sapiens]
          Length = 3122

 Score =  114 bits (286), Expect = 2e-25
 Identities = 59/176 (33%), Positives = 77/176 (43%), Gaps = 18/176 (10%)

Query: 155 GRCQCHGHAARCAA--RARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC 212
           G C C+GHA  C         RC C H+T G  C+ C P     PWR  T      C  C
Sbjct: 285 GMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEAC 344

Query: 213 SCNQHARRCRFNSELFRLS-----GGR--SGGVCERCRHHTAGRHCHYCQPGFWRDPSQP 265
           +C+  A  C ++  + R +      G+   GGVC  C  +TAG +C  C  GF+R     
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404

Query: 266 IFSRRACRACQCHPIGATGGTC---------NQTSGQCTCKLGVTGLTCNRCGPGY 312
               R C+ C C PIG+    C             G C CK G  G++C+RC  GY
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 50/171 (29%), Positives = 75/171 (43%), Gaps = 11/171 (6%)

Query: 138  LRVEFGGQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWP 197
            LR + GG+      G    CQC+GH++ C       + +C+HHT G  CE C   +    
Sbjct: 1401 LRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ-NCQHHTAGDFCERCALGYYG-- 1457

Query: 198  WRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPG 257
                    P+ C  C+C   +    F+     ++ G     C  C     G++C  C PG
Sbjct: 1458 ---IVKGLPNDCQQCACPLISSSNNFSPSC--VAEGLDDYRCTACPRGYEGQYCERCAPG 1512

Query: 258  FWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRC 308
            +   P  P  S   C+ C+C P G+    C+  +G CTC+ G TG  C+ C
Sbjct: 1513 YTGSPGNPGGS---CQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560



 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 56/186 (30%), Positives = 73/186 (39%), Gaps = 25/186 (13%)

Query: 147 GLAAAGLRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHP 206
           G    G+   CQC GHA  C         +C+ HT GP C+ C P     P    T    
Sbjct: 747 GTIFGGICEPCQCFGHAESC-DDVTGECLNCKDHTGGPYCDKCLPGFYGEP----TKGTS 801

Query: 207 HPCLPCSC------NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWR 260
             C PC+C      N  +  C  +  L        G +C+ C     G  C  C  G++ 
Sbjct: 802 EDCQPCACPLNIPSNNFSPTCHLDRSL--------GLICDGCPVGYTGPRCERCAEGYFG 853

Query: 261 DPSQPIFSRRACRACQCHP--IGATGGTCNQTSGQC-TCKLGVTGLTCNRCGPGYQQSRS 317
            PS P     +C+ CQC+     +  G+C+  SG C  CK G TG  C  C  GY     
Sbjct: 854 QPSVP---GGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV 910

Query: 318 PRMPCQ 323
               CQ
Sbjct: 911 DAKNCQ 916



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 29/179 (16%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
           C C    TG  CESC P HR    R         C PC C  HA  C   +         
Sbjct: 724 CQCPPGYTGSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCDDVT--------- 770

Query: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
             G C  C+ HT G +C  C PGF+ +P++   +   C+ C C P+       +      
Sbjct: 771 --GECLNCKDHTGGPYCDKCLPGFYGEPTKG--TSEDCQPCAC-PLNIPSNNFSP----- 820

Query: 295 TCKLGVT-GLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMS 352
           TC L  + GL C+ C  GY   R     C+R  E      + PG      QC +  + S
Sbjct: 821 TCHLDRSLGLICDGCPVGYTGPR-----CERCAEGYFGQPSVPGGSCQPCQCNDNLDFS 874



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 47/162 (29%), Positives = 64/162 (39%), Gaps = 27/162 (16%)

Query: 174  RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP----CLPCSCNQHARRCRFNSELFR 229
            +C C    +G  CE+C P       +P   R P P    C+PC CN H+  C   +    
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGG-RTPGPTLGTCVPCQCNGHSSLCDPETS--- 1434

Query: 230  LSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQ 289
                    +C+ C+HHTAG  C  C  G++            C+ C C  I ++      
Sbjct: 1435 --------ICQNCQHHTAGDFCERCALGYYGIVKG---LPNDCQQCACPLISSSNNFSPS 1483

Query: 290  TSGQ------CT-CKLGVTGLTCNRCGPGYQQS-RSPRMPCQ 323
               +      CT C  G  G  C RC PGY  S  +P   CQ
Sbjct: 1484 CVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ 1525



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 52/240 (21%), Positives = 84/240 (35%), Gaps = 52/240 (21%)

Query: 157  CQCH-GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
            C+C+ G +      ++  +C CR +  G  C+ C+             +    C+PC+CN
Sbjct: 918  CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL-------QSARGCVPCNCN 970

Query: 216  QHARR---CRFNSELFRLSGGRSGGVCERCRH---------------------------- 244
                +   C  + + +    G +G  C+RC H                            
Sbjct: 971  SFGSKSFDCEESGQCW-CQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGR 1029

Query: 245  -----HTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLG 299
                 +T G  C  C P  W            C+AC C  +G+    CN  +GQC C   
Sbjct: 1030 CICPPNTIGEKCSKCAPNTWGHSITT-----GCKACNCSTVGSLDFQCNVNTGQCNCHPK 1084

Query: 300  VTGLTCNRCGPGYQQSRSPRMPCQRIP--EATTTLATTPGAYSSDPQCQNYCNMSDTRVH 357
             +G  C  C  G+       +    +P  +ATT  + T     SD   Q  C ++   +H
Sbjct: 1085 FSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIH 1144



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 46/167 (27%), Positives = 60/167 (35%), Gaps = 41/167 (24%)

Query: 157  CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
            C+C      C  +    RC C  +T G  C  C P+   W     T      C  C+C+ 
Sbjct: 1014 CECSHLGNNCDPKTG--RCICPPNTIGEKCSKCAPN--TWGHSITTG-----CKACNCST 1064

Query: 217  HAR---RCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACR 273
                  +C  N+           G C  C    +G  C  C  G W  P         C 
Sbjct: 1065 VGSLDFQCNVNT-----------GQCN-CHPKFSGAKCTECSRGHWNYPR--------CN 1104

Query: 274  ACQCHPIGATGGTCNQTS---------GQCTCKLGVTGLTCNRCGPG 311
             C C   G    TC+  +         GQCTCK+ V G+ C+RC PG
Sbjct: 1105 LCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPG 1151



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 42/186 (22%), Positives = 58/186 (31%), Gaps = 74/186 (39%)

Query: 157 CQCHGHAARCAARARPPR-----------------CHCRHHTTGPGCESCRPSHRDWPWR 199
           C CHG A  C       R                  +C  +T G  CE+C     D  +R
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCT----DGFFR 399

Query: 200 P--ATPRHPHPCLPCSCN-------------QHARRCRFNSELFRLSGGRSGGV-CERC- 242
           P   +P +P PC PC C+             +HARR          +G   GGV C+RC 
Sbjct: 400 PKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTG--FGGVSCDRCA 457

Query: 243 -------------------------------RHHTAGRHCHYCQPGFWRDPSQPIFSRRA 271
                                          + +  G  C  C+ GF+        + + 
Sbjct: 458 RGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQED---NWKG 514

Query: 272 CRACQC 277
           C  C C
Sbjct: 515 CDECFC 520



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 24/62 (38%), Positives = 32/62 (51%), Gaps = 9/62 (14%)

Query: 293  QCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEAT--TTLATTPGAYSS--DPQ---C 345
            +C C LG +GL+C  C PG+ + RS   P  R P  T  T +      +SS  DP+   C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRS--QPGGRTPGPTLGTCVPCQCNGHSSLCDPETSIC 1436

Query: 346  QN 347
            QN
Sbjct: 1437 QN 1438


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 99.4 bits (246), Expect = 7e-21
 Identities = 55/166 (33%), Positives = 75/166 (45%), Gaps = 25/166 (15%)

Query: 156  RCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC- 214
            RC CHGH+  C       +  C+HHT GP CE C+P +    +  A    P  C  C C 
Sbjct: 1158 RCSCHGHSEACEPETGACQ-GCQHHTEGPRCEQCQPGY----YGDAQRGTPQDCQLCPCY 1212

Query: 215  -----NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSR 269
                  Q A  C  +++            C+ C    +GRHC  C PG++ +PSQ    +
Sbjct: 1213 GDPAAGQAAHTCFLDTD--------GHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQ 1264

Query: 270  RACRA-----CQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGP 310
            R  +      C C P G+    C+  +GQC CK  V GLTC+ C P
Sbjct: 1265 RDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKAQVEGLTCSHCRP 1309



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 53/186 (28%), Positives = 75/186 (40%), Gaps = 27/186 (14%)

Query: 174  RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
            +C C     GP C+ C   +   P    +  +   C  CSC+ H+  C   +        
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTP----SGLYLGTCERCSCHGHSEACEPET-------- 1172

Query: 234  RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCN----Q 289
               G C+ C+HHT G  C  CQPG++ D  +   + + C+ C C+   A G   +     
Sbjct: 1173 ---GACQGCQHHTEGPRCEQCQPGYYGDAQRG--TPQDCQLCPCYGDPAAGQAAHTCFLD 1227

Query: 290  TSGQCTCKL---GVTGLTCNRCGPGYQQSRSPRMPCQR---IPEATTTLATTPGAYSSDP 343
            T G  TC     G +G  C RC PGY  + S   PCQR   +P          G+ SS  
Sbjct: 1228 TDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQC 1287

Query: 344  QCQNYC 349
                 C
Sbjct: 1288 DAAGQC 1293



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 29/173 (16%)

Query: 157 CQCHGHAARCAARARPPRCHC---RHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCS 213
           C C+GHA+ C     P   HC   +H+T GP C  C+       +  A       C PC 
Sbjct: 764 CNCNGHASSCD----PVYGHCLNCQHNTEGPQCNKCKAGF----FGDAMKATATSCRPCP 815

Query: 214 CNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACR 273
           C       RF+   F  + G++   C+ C     GR C  C PG+  +P QP        
Sbjct: 816 CPYIDASRRFSDTCFLDTDGQA--TCDACAPGYTGRRCESCAPGYEGNPIQP-------- 865

Query: 274 ACQCHPIGATGGTCNQ-----TSGQ-CTCKLGVTGLTCNRCGPG--YQQSRSP 318
             +C P+      C++     TSG+ C CK  V G  CN C  G  +  +R+P
Sbjct: 866 GGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNP 918



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 48/146 (32%), Positives = 61/146 (41%), Gaps = 24/146 (16%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
           C C    +G  CESC       P  P    +   C  C+CN HA  C             
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGP----YLGTCSGCNCNGHASSC-----------DP 775

Query: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGAT---GGTC-NQT 290
             G C  C+H+T G  C+ C+ GF+ D  +   +  +CR C C  I A+     TC   T
Sbjct: 776 VYGHCLNCQHNTEGPQCNKCKAGFFGDAMKA--TATSCRPCPCPYIDASRRFSDTCFLDT 833

Query: 291 SGQCTCKL---GVTGLTCNRCGPGYQ 313
            GQ TC     G TG  C  C PGY+
Sbjct: 834 DGQATCDACAPGYTGRRCESCAPGYE 859



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 42/145 (28%), Positives = 60/145 (41%), Gaps = 24/145 (16%)

Query: 175  CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
            C C     G  C+ C P +     R  +  +   C  C CN H+  C   +         
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLCHPET--------- 1576

Query: 235  SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQC---HPIGATGGTCNQTS 291
              G C +C+H+ AG  C  C PG++ D +    +   C+ C C   +P      TC    
Sbjct: 1577 --GACSQCQHNAAGEFCELCAPGYYGDATAG--TPEDCQPCACPLTNPENMFSRTCESLG 1632

Query: 292  G---QCT-CKLGVTGLTCNRCGPGY 312
                +CT C+ G TG  C +CGPGY
Sbjct: 1633 AGGYRCTACEPGYTGQYCEQCGPGY 1657



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 74/314 (23%), Positives = 109/314 (34%), Gaps = 71/314 (22%)

Query: 157  CQCHGHAARCAARARPPRC-HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC- 214
            C+C+GH+  C        C  C+H+  G  CE C P +    +  AT   P  C PC+C 
Sbjct: 1563 CECNGHSDLC--HPETGACSQCQHNAAGEFCELCAPGY----YGDATAGTPEDCQPCACP 1616

Query: 215  -----NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSR 269
                 N  +R C         S G  G  C  C     G++C  C PG+  +PS      
Sbjct: 1617 LTNPENMFSRTCE--------SLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPS------ 1662

Query: 270  RACRACQCHPIGATGGTCNQTSGQCTCKL------------GVTGLTCNRCGPGYQQSRS 317
                          GG C   + Q    +            G   L C   G        
Sbjct: 1663 ------------VQGGQCLPETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYW 1710

Query: 318  PRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSLRRYCQQDHVLRAQVLAS 377
             R   + +P  T       G+    P  Q     SD  V++   R   Q +  RA++L +
Sbjct: 1711 SREDGRPVPSGTQ--QRHQGSELHFPSVQ----PSDAGVYICTCRNLHQSNTSRAELLVT 1764

Query: 378  EAAGPAWQRLAVRVLAVYKQRAQPVRRGDQDAWVPRADLTCGCLRLQPGTDYLLLGSAVG 437
            EA            + V +QR+Q VR        P AD+T  C        Y L+ + + 
Sbjct: 1765 EAPSKP------ITVTVEEQRSQSVR--------PGADVTFICTAKSKSPAYTLVWTRLH 1810

Query: 438  DPDPTRLILDRHGL 451
            +       +D +G+
Sbjct: 1811 NGKLPTRAMDFNGI 1824



 Score = 35.8 bits (81), Expect = 0.091
 Identities = 17/65 (26%), Positives = 25/65 (38%), Gaps = 5/65 (7%)

Query: 157  CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
            C C    +  +      +C C+    G  C  CRP H        +  +P  CLPC C  
Sbjct: 1275 CNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFH-----LSASNPDGCLPCFCMG 1329

Query: 217  HARRC 221
              ++C
Sbjct: 1330 ITQQC 1334



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 11/25 (44%), Positives = 15/25 (60%)

Query: 293  QCTCKLGVTGLTCNRCGPGYQQSRS 317
            +C C  G  GL+C  C PGY ++ S
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGS 1553



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 5/51 (9%)

Query: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNS 225
           C C+++  G  C  C     D  +  +T R+P  CL C C   +R C  +S
Sbjct: 892 CRCKNNVVGRLCNECA----DGSFHLST-RNPDGCLKCFCMGVSRHCTSSS 937


>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
          Length = 1668

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 41/106 (38%), Positives = 55/106 (51%), Gaps = 18/106 (16%)

Query: 209 CLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFS 268
           C+PC+CN H+ +C+  S           G+C  C+H+TAG HC  CQ G++ +       
Sbjct: 75  CVPCNCNGHSNQCQDGS-----------GICVNCQHNTAGEHCERCQEGYYGNAVHG--- 120

Query: 269 RRACRACQCHPIG--ATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
             +CRAC C      ATG   N    +C+CK G TG  C RC PGY
Sbjct: 121 --SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 164



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/189 (26%), Positives = 77/189 (40%), Gaps = 38/189 (20%)

Query: 119 ERVTFHSTPGPKATVAASHLRVEFGGQAGLAAAGLR-------GRC---QCHGHAARCAA 168
           +RV F   PG ++ + AS+  VEF    G +    R       GRC    C+GH+ +C  
Sbjct: 33  QRVPFLQPPG-QSQLQASY--VEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQD 89

Query: 169 RARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC---NQHARRCRFNS 225
            +     +C+H+T G  CE C+  +           H   C  C C   N  A  C  N 
Sbjct: 90  GSGIC-VNCQHNTAGEHCERCQEGYY------GNAVH-GSCRACPCPHTNSFATGCVVN- 140

Query: 226 ELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGG 285
                     G V   C+    G  C  C PG++ +P +      +C+ C C+  G   G
Sbjct: 141 ---------GGDVRCSCKAGYTGTQCERCAPGYFGNPQK---FGGSCQPCSCNSNGQL-G 187

Query: 286 TCNQTSGQC 294
           +C+  +G C
Sbjct: 188 SCHPLTGDC 196


>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
          Length = 1724

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 41/106 (38%), Positives = 55/106 (51%), Gaps = 18/106 (16%)

Query: 209 CLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFS 268
           C+PC+CN H+ +C+  S           G+C  C+H+TAG HC  CQ G++ +       
Sbjct: 75  CVPCNCNGHSNQCQDGS-----------GICVNCQHNTAGEHCERCQEGYYGNAVHG--- 120

Query: 269 RRACRACQCHPIG--ATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
             +CRAC C      ATG   N    +C+CK G TG  C RC PGY
Sbjct: 121 --SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 164



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/189 (26%), Positives = 77/189 (40%), Gaps = 38/189 (20%)

Query: 119 ERVTFHSTPGPKATVAASHLRVEFGGQAGLAAAGLR-------GRC---QCHGHAARCAA 168
           +RV F   PG ++ + AS+  VEF    G +    R       GRC    C+GH+ +C  
Sbjct: 33  QRVPFLQPPG-QSQLQASY--VEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQD 89

Query: 169 RARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC---NQHARRCRFNS 225
            +     +C+H+T G  CE C+  +           H   C  C C   N  A  C  N 
Sbjct: 90  GSGIC-VNCQHNTAGEHCERCQEGYY------GNAVH-GSCRACPCPHTNSFATGCVVN- 140

Query: 226 ELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGG 285
                     G V   C+    G  C  C PG++ +P +      +C+ C C+  G   G
Sbjct: 141 ---------GGDVRCSCKAGYTGTQCERCAPGYFGNPQK---FGGSCQPCSCNSNGQL-G 187

Query: 286 TCNQTSGQC 294
           +C+  +G C
Sbjct: 188 SCHPLTGDC 196


>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
          Length = 1111

 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 41/101 (40%), Positives = 56/101 (55%), Gaps = 8/101 (7%)

Query: 212 CSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRA 271
           C CN  +R+C F+ EL R +G  +G  C  C  +T G HC  C+ GF+R        R  
Sbjct: 28  CDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80

Query: 272 CRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
           C  C C+  G+    C+  SG+C+CK GVTG  C+RC PG+
Sbjct: 81  CLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGF 120



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 12/151 (7%)

Query: 157 CQCH-GHAARCAARARPPRCH-CRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC 214
           C CH G +           C+ C    TG  CE C   +   P+    P    PC PC C
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGP--VRPCQPCQC 519

Query: 215 NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRA 274
           N +      +    RL+G      C +C H+TAG +C  C+ G++ DP  P  + + CRA
Sbjct: 520 NNNVDPSA-SGNCDRLTGR-----CLKCIHNTAGIYCDQCKAGYFGDPLAPNPADK-CRA 572

Query: 275 CQCHPIGATGGTCNQTSGQCTCKLGVTGLTC 305
           C C+P+G+    C ++ G C CK G  G  C
Sbjct: 573 CNCNPMGSEPVGC-RSDGTCVCKPGFGGPNC 602



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 52/176 (29%), Positives = 66/176 (37%), Gaps = 36/176 (20%)

Query: 150 AAGLRGRCQCHGHAARCA-------ARARPPRC-HCRHHTTGPGCESCRPSHRDWPWRPA 201
           A   R  C C+G + +C              RC +C  +T G  CE C+           
Sbjct: 21  ATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY------- 73

Query: 202 TPRHPHPCLPCSCNQH---ARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGF 258
             R    CLPC+CN     + RC             + G C  C+    G  C  C PGF
Sbjct: 74  RHRERDRCLPCNCNSKGSLSARCD------------NSGRCS-CKPGVTGARCDRCLPGF 120

Query: 259 WR--DPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
               D       R     C C P G  G  C+  +G+C CK  VTG  C+RC  GY
Sbjct: 121 HMLTDAGCTQDQRLLDSKCDCDPAGIAG-PCD--AGRCVCKPAVTGERCDRCRSGY 173



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 47/197 (23%), Positives = 75/197 (38%), Gaps = 28/197 (14%)

Query: 203 PRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDP 262
           P  P  C PC C+ +   C    E   +       VC  C     G  C  C  G++ DP
Sbjct: 453 PHDPRSCKPCPCH-NGFSCSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDP 504

Query: 263 SQPIFSRRACRACQCHPI--GATGGTCNQTSGQCT-CKLGVTGLTCNRCGPGYQQSRSPR 319
                  R C+ CQC+     +  G C++ +G+C  C     G+ C++C  GY       
Sbjct: 505 FGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564

Query: 320 MPCQRIPEAT-TTLATTPGAYSSD-----------PQCQN---YCNMSDTRVHMSLRRYC 364
            P  +        + + P    SD           P C++    C     +V + + ++ 
Sbjct: 565 NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFM 624

Query: 365 QQDHVLRAQVLASEAAG 381
           QQ  + R + L S+A G
Sbjct: 625 QQ--LQRMEALISKAQG 639



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 40/162 (24%), Positives = 53/162 (32%), Gaps = 39/162 (24%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPH-PCLPCSCNQHARRCRFNSELFRLSG 232
           +C C     G  C+ C   ++    R +    P   C+PC+C                  
Sbjct: 381 QCICPVGYKGQFCQDCASGYK----RDSARLGPFGTCIPCNC------------------ 418

Query: 233 GRSGGVCER------CRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT 286
            + GG C+                C  C  GF+ DP  P    R+C+ C CH   +    
Sbjct: 419 -QGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP----RSCKPCPCHNGFSCSVM 473

Query: 287 CNQTSGQCT-CKLGVTGLTCNRCGPGY----QQSRSPRMPCQ 323
                  C  C  GVTG  C  C  GY         P  PCQ
Sbjct: 474 PETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 11/76 (14%)

Query: 153 LRGRCQCH--GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCL 210
           L  +C C   G A  C A     RC C+   TG  C+ CR  + +         +P  C 
Sbjct: 135 LDSKCDCDPAGIAGPCDAG----RCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCT 185

Query: 211 PCSCNQHARRCRFNSE 226
            C C  H+  CR ++E
Sbjct: 186 QCFCYGHSASCRSSAE 201


>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
          Length = 1193

 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 41/101 (40%), Positives = 56/101 (55%), Gaps = 8/101 (7%)

Query: 212 CSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRA 271
           C CN  +R+C F+ EL R +G  +G  C  C  +T G HC  C+ GF+R        R  
Sbjct: 28  CDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80

Query: 272 CRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
           C  C C+  G+    C+  SG+C+CK GVTG  C+RC PG+
Sbjct: 81  CLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGF 120



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 12/151 (7%)

Query: 157 CQCH-GHAARCAARARPPRCH-CRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC 214
           C CH G +           C+ C    TG  CE C   +   P+    P    PC PC C
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGP--VRPCQPCQC 519

Query: 215 NQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRA 274
           N +      +    RL+G      C +C H+TAG +C  C+ G++ DP  P  + + CRA
Sbjct: 520 NNNVDPSA-SGNCDRLTGR-----CLKCIHNTAGIYCDQCKAGYFGDPLAPNPADK-CRA 572

Query: 275 CQCHPIGATGGTCNQTSGQCTCKLGVTGLTC 305
           C C+P+G+    C ++ G C CK G  G  C
Sbjct: 573 CNCNPMGSEPVGC-RSDGTCVCKPGFGGPNC 602



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 52/176 (29%), Positives = 66/176 (37%), Gaps = 36/176 (20%)

Query: 150 AAGLRGRCQCHGHAARCA-------ARARPPRC-HCRHHTTGPGCESCRPSHRDWPWRPA 201
           A   R  C C+G + +C              RC +C  +T G  CE C+           
Sbjct: 21  ATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY------- 73

Query: 202 TPRHPHPCLPCSCNQH---ARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGF 258
             R    CLPC+CN     + RC             + G C  C+    G  C  C PGF
Sbjct: 74  RHRERDRCLPCNCNSKGSLSARCD------------NSGRCS-CKPGVTGARCDRCLPGF 120

Query: 259 WR--DPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
               D       R     C C P G  G  C+  +G+C CK  VTG  C+RC  GY
Sbjct: 121 HMLTDAGCTQDQRLLDSKCDCDPAGIAG-PCD--AGRCVCKPAVTGERCDRCRSGY 173



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 47/197 (23%), Positives = 75/197 (38%), Gaps = 28/197 (14%)

Query: 203 PRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDP 262
           P  P  C PC C+ +   C    E   +       VC  C     G  C  C  G++ DP
Sbjct: 453 PHDPRSCKPCPCH-NGFSCSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDP 504

Query: 263 SQPIFSRRACRACQCHPI--GATGGTCNQTSGQCT-CKLGVTGLTCNRCGPGYQQSRSPR 319
                  R C+ CQC+     +  G C++ +G+C  C     G+ C++C  GY       
Sbjct: 505 FGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564

Query: 320 MPCQRIPEAT-TTLATTPGAYSSD-----------PQCQN---YCNMSDTRVHMSLRRYC 364
            P  +        + + P    SD           P C++    C     +V + + ++ 
Sbjct: 565 NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFM 624

Query: 365 QQDHVLRAQVLASEAAG 381
           QQ  + R + L S+A G
Sbjct: 625 QQ--LQRMEALISKAQG 639



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 40/162 (24%), Positives = 53/162 (32%), Gaps = 39/162 (24%)

Query: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPH-PCLPCSCNQHARRCRFNSELFRLSG 232
           +C C     G  C+ C   ++    R +    P   C+PC+C                  
Sbjct: 381 QCICPVGYKGQFCQDCASGYK----RDSARLGPFGTCIPCNC------------------ 418

Query: 233 GRSGGVCER------CRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT 286
            + GG C+                C  C  GF+ DP  P    R+C+ C CH   +    
Sbjct: 419 -QGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP----RSCKPCPCHNGFSCSVM 473

Query: 287 CNQTSGQCT-CKLGVTGLTCNRCGPGY----QQSRSPRMPCQ 323
                  C  C  GVTG  C  C  GY         P  PCQ
Sbjct: 474 PETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 11/76 (14%)

Query: 153 LRGRCQCH--GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCL 210
           L  +C C   G A  C A     RC C+   TG  C+ CR  + +         +P  C 
Sbjct: 135 LDSKCDCDPAGIAGPCDAG----RCVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCT 185

Query: 211 PCSCNQHARRCRFNSE 226
            C C  H+  CR ++E
Sbjct: 186 QCFCYGHSASCRSSAE 201


>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 71/242 (29%), Positives = 93/242 (38%), Gaps = 33/242 (13%)

Query: 90  LILSAAWASGGPWRLLWHRPAWPGALGGPERVTFH----STPGPKATVAASHLRVEFGGQ 145
           + LS+AW S  P  LLW       A G      F     S  G +     S  RV  G  
Sbjct: 1   MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60

Query: 146 AGLAA---AG----LRGRC---QCHGHAARCAARARPPRC-HCRHHTTGPGCESCRPSHR 194
              A    AG    L G C    C+G++  C   +    C HC+ +TTG  CE C   + 
Sbjct: 61  PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSG--YCVHCQRNTTGEHCEKCLDGYI 118

Query: 195 DWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYC 254
               R A    P  C PC C        F    +R    ++G V   C  + AG +C  C
Sbjct: 119 GDSIRGA----PQFCQPCPCPL-PHLANFAESCYR----KNGAVRCICNENYAGPNCERC 169

Query: 255 QPGFWRDPSQPIFSRRACRACQCHPIGATG---GTCNQTSGQC-TCKLGVTGLTCNRCGP 310
            PG++     P+     C+ C C            C++ +GQC  C    TG  C RC P
Sbjct: 170 APGYY---GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226

Query: 311 GY 312
           GY
Sbjct: 227 GY 228



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 36/146 (24%), Positives = 54/146 (36%), Gaps = 19/146 (13%)

Query: 163 AARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCR 222
           A  C  +    RC C  +  GP CE C P +   P    +      C  C C+ ++    
Sbjct: 143 AESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS---- 193

Query: 223 FNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGA 282
            +  L         G C  C  +T G  C  C PG++ D        + C  C C     
Sbjct: 194 -DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNC----- 243

Query: 283 TGGTCNQTSGQCTCKLGVTGLTCNRC 308
            GG C+  +G+C  +       C++C
Sbjct: 244 GGGPCDSVTGECLEEGFEPPTGCDKC 269


>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 1823

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 71/242 (29%), Positives = 93/242 (38%), Gaps = 33/242 (13%)

Query: 90  LILSAAWASGGPWRLLWHRPAWPGALGGPERVTFH----STPGPKATVAASHLRVEFGGQ 145
           + LS+AW S  P  LLW       A G      F     S  G +     S  RV  G  
Sbjct: 1   MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60

Query: 146 AGLAA---AG----LRGRC---QCHGHAARCAARARPPRC-HCRHHTTGPGCESCRPSHR 194
              A    AG    L G C    C+G++  C   +    C HC+ +TTG  CE C   + 
Sbjct: 61  PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSG--YCVHCQRNTTGEHCEKCLDGYI 118

Query: 195 DWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYC 254
               R A    P  C PC C        F    +R    ++G V   C  + AG +C  C
Sbjct: 119 GDSIRGA----PQFCQPCPCPL-PHLANFAESCYR----KNGAVRCICNENYAGPNCERC 169

Query: 255 QPGFWRDPSQPIFSRRACRACQCHPIGATG---GTCNQTSGQC-TCKLGVTGLTCNRCGP 310
            PG++     P+     C+ C C            C++ +GQC  C    TG  C RC P
Sbjct: 170 APGYY---GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226

Query: 311 GY 312
           GY
Sbjct: 227 GY 228



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 19/132 (14%)

Query: 163 AARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCR 222
           A  C  +    RC C  +  GP CE C P +   P    +      C  C C+ ++    
Sbjct: 143 AESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS---- 193

Query: 223 FNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGA 282
            +  L         G C  C  +T G  C  C PG++ D        + C  C C     
Sbjct: 194 -DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNC----- 243

Query: 283 TGGTCNQTSGQC 294
            GG C+  +G+C
Sbjct: 244 GGGPCDSVTGEC 255


>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 71/242 (29%), Positives = 93/242 (38%), Gaps = 33/242 (13%)

Query: 90  LILSAAWASGGPWRLLWHRPAWPGALGGPERVTFH----STPGPKATVAASHLRVEFGGQ 145
           + LS+AW S  P  LLW       A G      F     S  G +     S  RV  G  
Sbjct: 1   MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60

Query: 146 AGLAA---AG----LRGRC---QCHGHAARCAARARPPRC-HCRHHTTGPGCESCRPSHR 194
              A    AG    L G C    C+G++  C   +    C HC+ +TTG  CE C   + 
Sbjct: 61  PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSG--YCVHCQRNTTGEHCEKCLDGYI 118

Query: 195 DWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYC 254
               R A    P  C PC C        F    +R    ++G V   C  + AG +C  C
Sbjct: 119 GDSIRGA----PQFCQPCPCPL-PHLANFAESCYR----KNGAVRCICNENYAGPNCERC 169

Query: 255 QPGFWRDPSQPIFSRRACRACQCHPIGATG---GTCNQTSGQC-TCKLGVTGLTCNRCGP 310
            PG++     P+     C+ C C            C++ +GQC  C    TG  C RC P
Sbjct: 170 APGYY---GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226

Query: 311 GY 312
           GY
Sbjct: 227 GY 228



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 36/146 (24%), Positives = 54/146 (36%), Gaps = 19/146 (13%)

Query: 163 AARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCR 222
           A  C  +    RC C  +  GP CE C P +   P    +      C  C C+ ++    
Sbjct: 143 AESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS---- 193

Query: 223 FNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGA 282
            +  L         G C  C  +T G  C  C PG++ D        + C  C C     
Sbjct: 194 -DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNC----- 243

Query: 283 TGGTCNQTSGQCTCKLGVTGLTCNRC 308
            GG C+  +G+C  +       C++C
Sbjct: 244 GGGPCDSVTGECLEEGFEPPTGCDKC 269


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.485 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,495,461
Number of Sequences: 37866
Number of extensions: 1454437
Number of successful extensions: 7532
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 158
Number of HSP's that attempted gapping in prelim test: 6012
Number of HSP's gapped (non-prelim): 879
length of query: 489
length of database: 18,247,518
effective HSP length: 106
effective length of query: 383
effective length of database: 14,233,722
effective search space: 5451515526
effective search space used: 5451515526
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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