Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 11968023
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11968023 zinc finger protein 106 homolog [Homo sapiens]
(1883 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11968023 zinc finger protein 106 homolog [Homo sapiens] 3791 0.0
gi|157266266 WD repeat domain 86 [Homo sapiens] 126 2e-28
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 112 3e-24
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 112 3e-24
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 112 3e-24
gi|32189425 WD repeat domain 69 [Homo sapiens] 97 2e-19
gi|48928050 F-box and WD repeat domain containing 11 isoform C [... 91 1e-17
gi|48928048 F-box and WD repeat domain containing 11 isoform A [... 91 1e-17
gi|48928046 F-box and WD repeat domain containing 11 isoform B [... 91 1e-17
gi|45594312 TNF receptor-associated factor 7 [Homo sapiens] 88 9e-17
gi|4502477 beta-transducin repeat containing protein isoform 2 [... 87 2e-16
gi|16117783 beta-transducin repeat containing protein isoform 1 ... 87 2e-16
gi|16554629 WD repeat domain 5 [Homo sapiens] 80 2e-14
gi|16554627 WD repeat domain 5 [Homo sapiens] 80 2e-14
gi|23199987 WD repeat domain 5B [Homo sapiens] 73 2e-12
gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens] 67 1e-10
gi|157694487 CMT1A duplicated region transcript 1 [Homo sapiens] 67 1e-10
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 67 2e-10
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 66 3e-10
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 64 2e-09
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 64 2e-09
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 64 2e-09
gi|38569484 kinesin family member 21A [Homo sapiens] 61 1e-08
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 58 8e-08
gi|153791298 mitogen-activated protein kinase organizer 1 [Homo ... 58 8e-08
gi|14150114 mitogen-activated protein kinase organizer 1 [Homo s... 58 8e-08
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 56 3e-07
gi|83716024 kinesin family member 21B [Homo sapiens] 55 5e-07
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 55 6e-07
gi|113865883 WD repeat domain 38 [Homo sapiens] 55 8e-07
>gi|11968023 zinc finger protein 106 homolog [Homo sapiens]
Length = 1883
Score = 3791 bits (9830), Expect = 0.0
Identities = 1883/1883 (100%), Positives = 1883/1883 (100%)
Query: 1 MPVGRIECPSSPSFPRDISHECRVCGVTEVGLSAYAKHISGQLHKDNVDAQEREDDGKGE 60
MPVGRIECPSSPSFPRDISHECRVCGVTEVGLSAYAKHISGQLHKDNVDAQEREDDGKGE
Sbjct: 1 MPVGRIECPSSPSFPRDISHECRVCGVTEVGLSAYAKHISGQLHKDNVDAQEREDDGKGE 60
Query: 61 EEEEDYFDKELIQLIKQRKEQSRQDEPSNSNQEINSDDRRPQWRREDRIPYQDRESYSQP 120
EEEEDYFDKELIQLIKQRKEQSRQDEPSNSNQEINSDDRRPQWRREDRIPYQDRESYSQP
Sbjct: 61 EEEEDYFDKELIQLIKQRKEQSRQDEPSNSNQEINSDDRRPQWRREDRIPYQDRESYSQP 120
Query: 121 AWHHRGPPQRDWKWEKDGFNNTRKNSFPHSLRNGGGPRGRSGWHKGVAGGSSTWFHNHSN 180
AWHHRGPPQRDWKWEKDGFNNTRKNSFPHSLRNGGGPRGRSGWHKGVAGGSSTWFHNHSN
Sbjct: 121 AWHHRGPPQRDWKWEKDGFNNTRKNSFPHSLRNGGGPRGRSGWHKGVAGGSSTWFHNHSN 180
Query: 181 SGGGWLSNSGAVDWNHNGTGRNSSWLSEGTGGFSSWHMNNSNGNWKSSVRSTNNWNYSGP 240
SGGGWLSNSGAVDWNHNGTGRNSSWLSEGTGGFSSWHMNNSNGNWKSSVRSTNNWNYSGP
Sbjct: 181 SGGGWLSNSGAVDWNHNGTGRNSSWLSEGTGGFSSWHMNNSNGNWKSSVRSTNNWNYSGP 240
Query: 241 GDKFQPGRNRNSNCQMEDMTMLWNKKSNKSNKYSHDRYNWQRQENDKLGTVATYRGPSEG 300
GDKFQPGRNRNSNCQMEDMTMLWNKKSNKSNKYSHDRYNWQRQENDKLGTVATYRGPSEG
Sbjct: 241 GDKFQPGRNRNSNCQMEDMTMLWNKKSNKSNKYSHDRYNWQRQENDKLGTVATYRGPSEG 300
Query: 301 FTSDKFPSEGLLDFNFEQLESQTTKQADTATSKVSGKNGSAAREKPRRWTPYPSQKTLDL 360
FTSDKFPSEGLLDFNFEQLESQTTKQADTATSKVSGKNGSAAREKPRRWTPYPSQKTLDL
Sbjct: 301 FTSDKFPSEGLLDFNFEQLESQTTKQADTATSKVSGKNGSAAREKPRRWTPYPSQKTLDL 360
Query: 361 QSGLKDITGNKSEMIEKPLFDFSLITTGIQEPQTDETRNSPTQKTQKEIHTGSLNHKASS 420
QSGLKDITGNKSEMIEKPLFDFSLITTGIQEPQTDETRNSPTQKTQKEIHTGSLNHKASS
Sbjct: 361 QSGLKDITGNKSEMIEKPLFDFSLITTGIQEPQTDETRNSPTQKTQKEIHTGSLNHKASS 420
Query: 421 DSAASFEVVRQCPTAEKPEQEHTPNKMPSLKSPLLPCPATKSLSQKQDPKNISKNTKTNF 480
DSAASFEVVRQCPTAEKPEQEHTPNKMPSLKSPLLPCPATKSLSQKQDPKNISKNTKTNF
Sbjct: 421 DSAASFEVVRQCPTAEKPEQEHTPNKMPSLKSPLLPCPATKSLSQKQDPKNISKNTKTNF 480
Query: 481 FSPGEHSNPSNKPTVEDNHGPYISKLRSSCPHVLKGNKSTFGSQKQSGDNLNDTLRKAKE 540
FSPGEHSNPSNKPTVEDNHGPYISKLRSSCPHVLKGNKSTFGSQKQSGDNLNDTLRKAKE
Sbjct: 481 FSPGEHSNPSNKPTVEDNHGPYISKLRSSCPHVLKGNKSTFGSQKQSGDNLNDTLRKAKE 540
Query: 541 VLQCHESLQNPLLSTSKSTRNYAKASRNVEESEKGSLKIEFQVHALEDESDGETSDTEKH 600
VLQCHESLQNPLLSTSKSTRNYAKASRNVEESEKGSLKIEFQVHALEDESDGETSDTEKH
Sbjct: 541 VLQCHESLQNPLLSTSKSTRNYAKASRNVEESEKGSLKIEFQVHALEDESDGETSDTEKH 600
Query: 601 GTKIGTLGSATTELLSGSTRTADEKEEDDRILKTSRELSTSPCNPIVRQKESELQMTSAA 660
GTKIGTLGSATTELLSGSTRTADEKEEDDRILKTSRELSTSPCNPIVRQKESELQMTSAA
Sbjct: 601 GTKIGTLGSATTELLSGSTRTADEKEEDDRILKTSRELSTSPCNPIVRQKESELQMTSAA 660
Query: 661 SPHPGLLLDLKTSLEDAQVDDSIKSHVSYETEGFESASLDAELQKSDISQPSGPLLPELS 720
SPHPGLLLDLKTSLEDAQVDDSIKSHVSYETEGFESASLDAELQKSDISQPSGPLLPELS
Sbjct: 661 SPHPGLLLDLKTSLEDAQVDDSIKSHVSYETEGFESASLDAELQKSDISQPSGPLLPELS 720
Query: 721 KLGFPASLQRDLTRHISLKSKTGVHLPEPNLNSARRIRNISGHRKSETEKESGLKPTLRQ 780
KLGFPASLQRDLTRHISLKSKTGVHLPEPNLNSARRIRNISGHRKSETEKESGLKPTLRQ
Sbjct: 721 KLGFPASLQRDLTRHISLKSKTGVHLPEPNLNSARRIRNISGHRKSETEKESGLKPTLRQ 780
Query: 781 ILNASRRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEALDLDGEPDLSSLEG 840
ILNASRRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEALDLDGEPDLSSLEG
Sbjct: 781 ILNASRRNVNWEQVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEALDLDGEPDLSSLEG 840
Query: 841 FQWEGVSISSSPGLARKRSLSESSVIMDRAPSVYSFFSEEGTGKENEPQQMVSPSNSLRA 900
FQWEGVSISSSPGLARKRSLSESSVIMDRAPSVYSFFSEEGTGKENEPQQMVSPSNSLRA
Sbjct: 841 FQWEGVSISSSPGLARKRSLSESSVIMDRAPSVYSFFSEEGTGKENEPQQMVSPSNSLRA 900
Query: 901 GQSQKATMHLKQEVTPRAASLRTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQER 960
GQSQKATMHLKQEVTPRAASLRTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQER
Sbjct: 901 GQSQKATMHLKQEVTPRAASLRTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQER 960
Query: 961 SIPPSENQNSQESNGEGNCLSSSASSALAISSLADAATDSSCTSGAEQNDGQSIRKKRRA 1020
SIPPSENQNSQESNGEGNCLSSSASSALAISSLADAATDSSCTSGAEQNDGQSIRKKRRA
Sbjct: 961 SIPPSENQNSQESNGEGNCLSSSASSALAISSLADAATDSSCTSGAEQNDGQSIRKKRRA 1020
Query: 1021 TGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLNISLREEELSKSLQCMDNNLLQARAA 1080
TGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLNISLREEELSKSLQCMDNNLLQARAA
Sbjct: 1021 TGDGSSPELPSLERKNKRRKIKGKKERSQVDQLLNISLREEELSKSLQCMDNNLLQARAA 1080
Query: 1081 LQTAYVEVQRLLMLKQQITMEMSALRTHRIQILQGLQETYEPSEHPDQVPCSLTRERRNS 1140
LQTAYVEVQRLLMLKQQITMEMSALRTHRIQILQGLQETYEPSEHPDQVPCSLTRERRNS
Sbjct: 1081 LQTAYVEVQRLLMLKQQITMEMSALRTHRIQILQGLQETYEPSEHPDQVPCSLTRERRNS 1140
Query: 1141 RSQTSIDAALLPTPFFPLFLEPPSSHVSPSPTGASLQITTSPTFQTHGSVPAPDSSVQIK 1200
RSQTSIDAALLPTPFFPLFLEPPSSHVSPSPTGASLQITTSPTFQTHGSVPAPDSSVQIK
Sbjct: 1141 RSQTSIDAALLPTPFFPLFLEPPSSHVSPSPTGASLQITTSPTFQTHGSVPAPDSSVQIK 1200
Query: 1201 QEPMSPEQDENVNAVPPSSACNVSKELLEANREISDSCPVYPVITARLSLPESTESFHEP 1260
QEPMSPEQDENVNAVPPSSACNVSKELLEANREISDSCPVYPVITARLSLPESTESFHEP
Sbjct: 1201 QEPMSPEQDENVNAVPPSSACNVSKELLEANREISDSCPVYPVITARLSLPESTESFHEP 1260
Query: 1261 SQELKFSVEQRNTRNRENSPSSQSAGLSSINKEGEEPTKGNSGSEACTSSFLRLSFASET 1320
SQELKFSVEQRNTRNRENSPSSQSAGLSSINKEGEEPTKGNSGSEACTSSFLRLSFASET
Sbjct: 1261 SQELKFSVEQRNTRNRENSPSSQSAGLSSINKEGEEPTKGNSGSEACTSSFLRLSFASET 1320
Query: 1321 PLEKEPHSPADQPEQQAESTLTSAETRGSKKKKKLRKKKSLRAAHVPENSDTEQDVLTVK 1380
PLEKEPHSPADQPEQQAESTLTSAETRGSKKKKKLRKKKSLRAAHVPENSDTEQDVLTVK
Sbjct: 1321 PLEKEPHSPADQPEQQAESTLTSAETRGSKKKKKLRKKKSLRAAHVPENSDTEQDVLTVK 1380
Query: 1381 PVRKVKAGKLIKGGKVTTSTWEDSRTGREQESVRDEPDSDSSLEVLEIPNPQLEVVAIDS 1440
PVRKVKAGKLIKGGKVTTSTWEDSRTGREQESVRDEPDSDSSLEVLEIPNPQLEVVAIDS
Sbjct: 1381 PVRKVKAGKLIKGGKVTTSTWEDSRTGREQESVRDEPDSDSSLEVLEIPNPQLEVVAIDS 1440
Query: 1441 SESGEEKPDSPSKKDIWNSTEQNPLETSRSGCDEVSSTSEIGTRYKDGIPVSVAETQTVI 1500
SESGEEKPDSPSKKDIWNSTEQNPLETSRSGCDEVSSTSEIGTRYKDGIPVSVAETQTVI
Sbjct: 1441 SESGEEKPDSPSKKDIWNSTEQNPLETSRSGCDEVSSTSEIGTRYKDGIPVSVAETQTVI 1500
Query: 1501 SSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVS 1560
SSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVS
Sbjct: 1501 SSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVS 1560
Query: 1561 RKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLC 1620
RKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLC
Sbjct: 1561 RKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLC 1620
Query: 1621 LHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDC 1680
LHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDC
Sbjct: 1621 LHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDC 1680
Query: 1681 TISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHN 1740
TISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHN
Sbjct: 1681 TISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHN 1740
Query: 1741 HAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDG 1800
HAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDG
Sbjct: 1741 HAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDG 1800
Query: 1801 SIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDAFFTAR 1860
SIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDAFFTAR
Sbjct: 1801 SIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPNFQTLKCRWKNCDAFFTAR 1860
Query: 1861 KGSKQDAAGHIERHAEDDSKIDS 1883
KGSKQDAAGHIERHAEDDSKIDS
Sbjct: 1861 KGSKQDAAGHIERHAEDDSKIDS 1883
>gi|157266266 WD repeat domain 86 [Homo sapiens]
Length = 376
Score = 126 bits (316), Expect = 2e-28
Identities = 82/293 (27%), Positives = 140/293 (47%), Gaps = 25/293 (8%)
Query: 1528 EGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNA 1587
+GH++ V Q+ +TCSAD T+R +++++ +C+ V+ GHTS VN +LV N
Sbjct: 54 QGHESYVTFCQLEDEAAFTCSADCTIRRWDVLTGQCLQVYRGHTSIVNRILVA-----NN 108
Query: 1588 ALYTGSSDHTIRCYNVKSRECVEQLQLEDR---VLCLHSRWRI--------------LYA 1630
L++ S D T R ++V + + + L + W + L
Sbjct: 109 QLFSSSYDRTARVWSVDKGQMSREFRGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLLVT 168
Query: 1631 GLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNG 1690
G +GT + + + + H AV CL G GS D TI D +G
Sbjct: 169 GSTDGTAKVWQVASGCCHQTLRGH-TGAVLCLVLDTPGHTAF--TGSTDATIRAWDILSG 225
Query: 1691 LLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILG 1750
LR H +++C+++VN LV+SGS+D++V TGE VR + H V+ +
Sbjct: 226 EQLRVFREHRGSVICLELVNRLVYSGSADRTVKCWLADTGECVRTFTAHRRNVSALKYHA 285
Query: 1751 KVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQ 1803
+ T D R ++ QS + +V+ GH +I C+ +H ++YT +DG+++
Sbjct: 286 GTLFTGSGDACARAFDAQSGELRRVFRGHTFIINCIQVHGQVLYTASHDGALR 338
Score = 98.6 bits (244), Expect = 5e-20
Identities = 70/259 (27%), Positives = 124/259 (47%), Gaps = 25/259 (9%)
Query: 1527 FEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLV------- 1579
+ GH + VN I + N L++ S D+T RV+++ + F GH NC+L
Sbjct: 93 YRGHTSIVNRILVANNQLFSSSYDRTARVWSVDKGQMSREFRGHR---NCVLTLAYSAPW 149
Query: 1580 -------TQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQLED-RVLCL--HSRWRILY 1629
+ + L TGS+D T + + V S C + L+ VLCL + +
Sbjct: 150 DLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAF 209
Query: 1630 AGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARN 1689
G + T+ ++I + ++L +F H +V CL E +L+ GS D T+ A
Sbjct: 210 TGSTDATIRAWDILSGEQLRVFREHRG-SVICL----ELVNRLVYSGSADRTVKCWLADT 264
Query: 1690 GLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNIL 1749
G +RT H + + +K +F+GS D A + +GEL R+++GH + + +
Sbjct: 265 GECVRTFTAHRRNVSALKYHAGTLFTGSGDACARAFDAQSGELRRVFRGHTFIINCIQVH 324
Query: 1750 GKVMVTACLDKFVRVYELQ 1768
G+V+ TA D +R+++++
Sbjct: 325 GQVLYTASHDGALRLWDVR 343
Score = 54.7 bits (130), Expect = 8e-07
Identities = 26/128 (20%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Query: 1659 VSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSS 1718
++ L+ + +G R L+ GS D T + +G L+GH + ++ ++ F+ S+
Sbjct: 18 INWLSLSPDGQR--LLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQLEDEAAFTCSA 75
Query: 1719 DQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGG 1778
D ++ ++ TG+ +++Y+GH V + + + ++ D+ RV+ + + + G
Sbjct: 76 DCTIRRWDVLTGQCLQVYRGHTSIVNRILVANNQLFSSSYDRTARVWSVDKGQMSREFRG 135
Query: 1779 HKDMIMCM 1786
H++ ++ +
Sbjct: 136 HRNCVLTL 143
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+F H+ V+A++ L+T S D R ++ S + VF GHT +NC+ V
Sbjct: 270 TFTAHRRNVSALKYHAGTLFTGSGDACARAFDAQSGELRRVFRGHTFIINCIQV-----H 324
Query: 1586 NAALYTGSSDHTIRCYNVK 1604
LYT S D +R ++V+
Sbjct: 325 GQVLYTASHDGALRLWDVR 343
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 112 bits (281), Expect = 3e-24
Identities = 68/281 (24%), Positives = 139/281 (49%), Gaps = 15/281 (5%)
Query: 1528 EGHQA-AVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKN 1586
+GH + +Q GN + + S D T++V++ V+ KC+ GHT V + ++
Sbjct: 259 KGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV-----WSSQMRD 313
Query: 1587 AALYTGSSDHTIRCYNVKSRECVEQLQLE-DRVLCLHSRWRILYAGLANGTVVTFNIKNN 1645
+ +GS+D T++ +N ++ EC+ L V C+H + + +G + T+ ++I+
Sbjct: 314 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETG 373
Query: 1646 KRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILC 1705
+ L + H V+ + Q R++ V G+YD + V D L TL+GH+ +
Sbjct: 374 QCLHVLMGH----VAAVRCVQYDGRRV-VSGAYDFMVKVWDPETETCLHTLQGHTNRVYS 428
Query: 1706 MKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVY 1765
++ V SGS D S+ ++ TG + GH + + + ++V+ D V+++
Sbjct: 429 LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIW 488
Query: 1766 ELQSHDRLQVYGG---HKDMIMCMTIHKSMIYTGCYDGSIQ 1803
++++ LQ G H+ + C+ +K+ + T DG+++
Sbjct: 489 DIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVK 529
Score = 74.7 bits (182), Expect = 8e-13
Identities = 49/210 (23%), Positives = 101/210 (48%), Gaps = 14/210 (6%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
GH + V + + + + S D T+RV+++ + +C+ V GH + V C+ Q G+
Sbjct: 341 GHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCV---QYDGRRVV 397
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQLE-DRVLCLHSRWRILYAGLANGTVVTFNIKNNKR 1647
+G+ D ++ ++ ++ C+ LQ +RV L + +G + ++ ++++
Sbjct: 398 --SGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNC 455
Query: 1648 LEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEG---HSKTIL 1704
+ H L + E +LV G+ D T+ + D + G L+TL+G H +
Sbjct: 456 IHTLTGH-----QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT 510
Query: 1705 CMKVVNDLVFSGSSDQSVHAHNIHTGELVR 1734
C++ + V + S D +V ++ TGE +R
Sbjct: 511 CLQFNKNFVITSSDDGTVKLWDLKTGEFIR 540
Score = 74.3 bits (181), Expect = 1e-12
Identities = 48/179 (26%), Positives = 87/179 (48%), Gaps = 5/179 (2%)
Query: 1621 LHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDC 1680
+HS W+ Y + + K ++ + H ++CL G R +V GS D
Sbjct: 229 IHSPWKSAYIR-QHRIDTNWRRGELKSPKVLKGHDDHVITCLQFC--GNR--IVSGSDDN 283
Query: 1681 TISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHN 1740
T+ V A G LRTL GH+ + ++ ++++ SGS+D+++ N TGE + GH
Sbjct: 284 TLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHT 343
Query: 1741 HAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYD 1799
V +++ K +V+ D +RV+++++ L V GH + C+ + +G YD
Sbjct: 344 STVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYD 402
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/125 (24%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+ +GH V ++Q G + + S D ++RV+++ + CI GH S L + K
Sbjct: 418 TLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS-----LTSGMELK 472
Query: 1586 NAALYTGSSDHTIRCYNVKSRECVEQLQ----LEDRVLCLHSRWRILYAGLANGTVVTFN 1641
+ L +G++D T++ +++K+ +C++ LQ + V CL + +GTV ++
Sbjct: 473 DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWD 532
Query: 1642 IKNNK 1646
+K +
Sbjct: 533 LKTGE 537
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 112 bits (281), Expect = 3e-24
Identities = 68/281 (24%), Positives = 139/281 (49%), Gaps = 15/281 (5%)
Query: 1528 EGHQA-AVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKN 1586
+GH + +Q GN + + S D T++V++ V+ KC+ GHT V + ++
Sbjct: 377 KGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV-----WSSQMRD 431
Query: 1587 AALYTGSSDHTIRCYNVKSRECVEQLQLE-DRVLCLHSRWRILYAGLANGTVVTFNIKNN 1645
+ +GS+D T++ +N ++ EC+ L V C+H + + +G + T+ ++I+
Sbjct: 432 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETG 491
Query: 1646 KRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILC 1705
+ L + H V+ + Q R++ V G+YD + V D L TL+GH+ +
Sbjct: 492 QCLHVLMGH----VAAVRCVQYDGRRV-VSGAYDFMVKVWDPETETCLHTLQGHTNRVYS 546
Query: 1706 MKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVY 1765
++ V SGS D S+ ++ TG + GH + + + ++V+ D V+++
Sbjct: 547 LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIW 606
Query: 1766 ELQSHDRLQVYGG---HKDMIMCMTIHKSMIYTGCYDGSIQ 1803
++++ LQ G H+ + C+ +K+ + T DG+++
Sbjct: 607 DIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVK 647
Score = 74.7 bits (182), Expect = 8e-13
Identities = 49/210 (23%), Positives = 101/210 (48%), Gaps = 14/210 (6%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
GH + V + + + + S D T+RV+++ + +C+ V GH + V C+ Q G+
Sbjct: 459 GHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCV---QYDGRRVV 515
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQLE-DRVLCLHSRWRILYAGLANGTVVTFNIKNNKR 1647
+G+ D ++ ++ ++ C+ LQ +RV L + +G + ++ ++++
Sbjct: 516 --SGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNC 573
Query: 1648 LEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEG---HSKTIL 1704
+ H L + E +LV G+ D T+ + D + G L+TL+G H +
Sbjct: 574 IHTLTGH-----QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT 628
Query: 1705 CMKVVNDLVFSGSSDQSVHAHNIHTGELVR 1734
C++ + V + S D +V ++ TGE +R
Sbjct: 629 CLQFNKNFVITSSDDGTVKLWDLKTGEFIR 658
Score = 74.3 bits (181), Expect = 1e-12
Identities = 48/179 (26%), Positives = 87/179 (48%), Gaps = 5/179 (2%)
Query: 1621 LHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDC 1680
+HS W+ Y + + K ++ + H ++CL G R +V GS D
Sbjct: 347 IHSPWKSAYIR-QHRIDTNWRRGELKSPKVLKGHDDHVITCLQFC--GNR--IVSGSDDN 401
Query: 1681 TISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHN 1740
T+ V A G LRTL GH+ + ++ ++++ SGS+D+++ N TGE + GH
Sbjct: 402 TLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHT 461
Query: 1741 HAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYD 1799
V +++ K +V+ D +RV+++++ L V GH + C+ + +G YD
Sbjct: 462 STVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYD 520
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/125 (24%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+ +GH V ++Q G + + S D ++RV+++ + CI GH S L + K
Sbjct: 536 TLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS-----LTSGMELK 590
Query: 1586 NAALYTGSSDHTIRCYNVKSRECVEQLQ----LEDRVLCLHSRWRILYAGLANGTVVTFN 1641
+ L +G++D T++ +++K+ +C++ LQ + V CL + +GTV ++
Sbjct: 591 DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWD 650
Query: 1642 IKNNK 1646
+K +
Sbjct: 651 LKTGE 655
Score = 35.0 bits (79), Expect = 0.69
Identities = 18/53 (33%), Positives = 32/53 (60%), Gaps = 3/53 (5%)
Query: 47 NVDAQEREDDGKGEEEEEDYFDKELIQL---IKQRKEQSRQDEPSNSNQEINS 96
N + QE +++ GE++EED ++E+ Q Q + SR+DE +++N NS
Sbjct: 94 NQEEQEEDEEHAGEQDEEDEEEEEMDQESDDFDQSDDSSREDEHTHTNSVTNS 146
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 112 bits (281), Expect = 3e-24
Identities = 68/281 (24%), Positives = 139/281 (49%), Gaps = 15/281 (5%)
Query: 1528 EGHQA-AVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKN 1586
+GH + +Q GN + + S D T++V++ V+ KC+ GHT V + ++
Sbjct: 297 KGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV-----WSSQMRD 351
Query: 1587 AALYTGSSDHTIRCYNVKSRECVEQLQLE-DRVLCLHSRWRILYAGLANGTVVTFNIKNN 1645
+ +GS+D T++ +N ++ EC+ L V C+H + + +G + T+ ++I+
Sbjct: 352 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETG 411
Query: 1646 KRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILC 1705
+ L + H V+ + Q R++ V G+YD + V D L TL+GH+ +
Sbjct: 412 QCLHVLMGH----VAAVRCVQYDGRRV-VSGAYDFMVKVWDPETETCLHTLQGHTNRVYS 466
Query: 1706 MKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVY 1765
++ V SGS D S+ ++ TG + GH + + + ++V+ D V+++
Sbjct: 467 LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIW 526
Query: 1766 ELQSHDRLQVYGG---HKDMIMCMTIHKSMIYTGCYDGSIQ 1803
++++ LQ G H+ + C+ +K+ + T DG+++
Sbjct: 527 DIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVK 567
Score = 74.7 bits (182), Expect = 8e-13
Identities = 49/210 (23%), Positives = 101/210 (48%), Gaps = 14/210 (6%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
GH + V + + + + S D T+RV+++ + +C+ V GH + V C+ Q G+
Sbjct: 379 GHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCV---QYDGRRVV 435
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQLE-DRVLCLHSRWRILYAGLANGTVVTFNIKNNKR 1647
+G+ D ++ ++ ++ C+ LQ +RV L + +G + ++ ++++
Sbjct: 436 --SGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNC 493
Query: 1648 LEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEG---HSKTIL 1704
+ H L + E +LV G+ D T+ + D + G L+TL+G H +
Sbjct: 494 IHTLTGH-----QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT 548
Query: 1705 CMKVVNDLVFSGSSDQSVHAHNIHTGELVR 1734
C++ + V + S D +V ++ TGE +R
Sbjct: 549 CLQFNKNFVITSSDDGTVKLWDLKTGEFIR 578
Score = 74.3 bits (181), Expect = 1e-12
Identities = 48/179 (26%), Positives = 87/179 (48%), Gaps = 5/179 (2%)
Query: 1621 LHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDC 1680
+HS W+ Y + + K ++ + H ++CL G R +V GS D
Sbjct: 267 IHSPWKSAYIR-QHRIDTNWRRGELKSPKVLKGHDDHVITCLQFC--GNR--IVSGSDDN 321
Query: 1681 TISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHN 1740
T+ V A G LRTL GH+ + ++ ++++ SGS+D+++ N TGE + GH
Sbjct: 322 TLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHT 381
Query: 1741 HAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYD 1799
V +++ K +V+ D +RV+++++ L V GH + C+ + +G YD
Sbjct: 382 STVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYD 440
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/125 (24%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+ +GH V ++Q G + + S D ++RV+++ + CI GH S L + K
Sbjct: 456 TLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS-----LTSGMELK 510
Query: 1586 NAALYTGSSDHTIRCYNVKSRECVEQLQ----LEDRVLCLHSRWRILYAGLANGTVVTFN 1641
+ L +G++D T++ +++K+ +C++ LQ + V CL + +GTV ++
Sbjct: 511 DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWD 570
Query: 1642 IKNNK 1646
+K +
Sbjct: 571 LKTGE 575
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 96.7 bits (239), Expect = 2e-19
Identities = 78/293 (26%), Positives = 141/293 (48%), Gaps = 18/293 (6%)
Query: 1526 SFEGHQAAVNAIQI---FGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQT 1582
+ EGH+ V AI +G+ + T S DKT +++++ + KC F GHT+++ CL
Sbjct: 129 TLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCL---SF 185
Query: 1583 SGKNAALYTGSSDHTIRCYNVKSRECVEQLQ---LEDRVLCLHSRWRILYAGLANGTVVT 1639
+ ++ + TGS D T + +++++ E V L+ E L ++ + G + TVV
Sbjct: 186 NPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVV 245
Query: 1640 FNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGH 1699
++ +++ I H + + L++ GS D T + DA NG + TL GH
Sbjct: 246 WDADTGRKVNILIGH---CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGH 302
Query: 1700 SKTIL--CMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVV--NILGKVMVT 1755
IL C L+ + S+D + + T + + +GH ++ + N G ++T
Sbjct: 303 DDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLT 362
Query: 1756 ACLDKFVRVYELQSHDRLQVYGGHKDMIM-CMTIHK-SMIYTGCYDGSIQAVR 1806
DK R+++ Q+ LQV GH D I C +K +++ TG D + + R
Sbjct: 363 GSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 415
Score = 59.3 bits (142), Expect = 3e-08
Identities = 34/136 (25%), Positives = 68/136 (50%), Gaps = 7/136 (5%)
Query: 1674 VVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVN---DLVFSGSSDQSVHAHNIHTG 1730
+ GSYD T + D +G L TLEGH + + N D + +GS D++ ++ TG
Sbjct: 108 ITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETG 167
Query: 1731 ELVRIYKGHNHAVTVV--NILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTI 1788
+ ++GH + + N ++ T +D +++++Q+ + + GH I+ ++
Sbjct: 168 KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSF 227
Query: 1789 HKS--MIYTGCYDGSI 1802
+ S I TG +D ++
Sbjct: 228 NTSGDRIITGSFDHTV 243
Score = 57.0 bits (136), Expect = 2e-07
Identities = 43/198 (21%), Positives = 86/198 (43%), Gaps = 20/198 (10%)
Query: 1418 DSDSSLEVLEIPNPQLEVVAIDSSESGEEKPDSPSKKDI--WNSTEQNPLETSRSGCDEV 1475
D + EV + E++++ + SG+ + W++ + C E+
Sbjct: 205 DIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEI 264
Query: 1476 SSTSEIGTRYKDGIPVSVAETQTVISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVN 1535
SS S + + + + + + N +++ G DDE + F+
Sbjct: 265 SSAS-----FNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFD------- 312
Query: 1536 AIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSD 1595
G L+ T SAD T R+++ +RKCI EGH +++ + + + L TGSSD
Sbjct: 313 ---YTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKI---SFNPQGNHLLTGSSD 366
Query: 1596 HTIRCYNVKSRECVEQLQ 1613
T R ++ ++ +C++ L+
Sbjct: 367 KTARIWDAQTGQCLQVLE 384
>gi|48928050 F-box and WD repeat domain containing 11 isoform C [Homo
sapiens]
Length = 542
Score = 90.9 bits (224), Expect = 1e-17
Identities = 62/230 (26%), Positives = 111/230 (48%), Gaps = 26/230 (11%)
Query: 1550 DKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECV 1609
D ++++++ S +C+ V GHT V CL + + TGSSD T+R ++V + E +
Sbjct: 259 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDER-----VIVTGSSDSTVRVWDVNTGEVL 313
Query: 1610 EQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGA 1669
L +H +L+ +NG +VT + ++ + +++ ++ L G
Sbjct: 314 NTL--------IHHNEAVLHLRFSNGLMVTCS--KDRSIAVWDMASATDIT-LRRVLVGH 362
Query: 1670 R----------KLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSD 1719
R K +V S D TI V +RTL GH + I C++ + LV SGSSD
Sbjct: 363 RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSD 422
Query: 1720 QSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQS 1769
++ +I G +R+ +GH V + K +V+ D ++V++LQ+
Sbjct: 423 NTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQA 472
Score = 62.0 bits (149), Expect = 5e-09
Identities = 51/202 (25%), Positives = 94/202 (46%), Gaps = 22/202 (10%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKV------NCLLVTQT 1582
GH +V +Q ++ T S+D TVRV+++ + + + H V N L+VT +
Sbjct: 278 GHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCS 337
Query: 1583 SGKNAALY--TGSSDHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTF 1640
++ A++ ++D T+R V R V + +D+ + S + T+ +
Sbjct: 338 KDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSAS---------GDRTIKVW 388
Query: 1641 NIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS 1700
+ + + H R ++CL + +L+V GS D TI + D G LR LEGH
Sbjct: 389 STSTCEFVRTLNGH-KRGIACL----QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHE 443
Query: 1701 KTILCMKVVNDLVFSGSSDQSV 1722
+ + C++ N + SG+ D +
Sbjct: 444 ELVRCIRFDNKRIVSGAYDGKI 465
Score = 57.8 bits (138), Expect = 1e-07
Identities = 39/171 (22%), Positives = 83/171 (48%), Gaps = 20/171 (11%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
GH+AAVN + + + S D+T++V++ + + + GH + CL ++
Sbjct: 361 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL-----QYRDRL 415
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQ-LEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKR 1647
+ +GSSD+TIR ++++ C+ L+ E+ V C+ + + +G +G + ++++
Sbjct: 416 VVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQ---- 471
Query: 1648 LEIFECHGPRAVSCLATAQEGARKL---------LVVGSYDCTISVRDARN 1689
+ P + CL T E + ++ ++ S+D TI + D N
Sbjct: 472 -AALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLN 521
Score = 43.9 bits (102), Expect = 0.001
Identities = 24/104 (23%), Positives = 52/104 (50%)
Query: 1699 HSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACL 1758
+SK + C++ ++ + SG D S+ + + E +++ GH +V + +V+VT
Sbjct: 239 NSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSS 298
Query: 1759 DKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSI 1802
D VRV+++ + + L H + ++ + ++ T D SI
Sbjct: 299 DSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSI 342
Score = 40.4 bits (93), Expect = 0.016
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+ GH+ + +Q L+ + S+D T+R++++ C+ V EGH V C+
Sbjct: 398 TLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF-----D 452
Query: 1586 NAALYTGSSDHTIRCYNVKS 1605
N + +G+ D I+ +++++
Sbjct: 453 NKRIVSGAYDGKIKVWDLQA 472
Score = 31.6 bits (70), Expect = 7.6
Identities = 12/56 (21%), Positives = 31/56 (55%)
Query: 1753 MVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQAVRLN 1808
+++ D +++++ S + L+V GH ++C+ + +I TG D +++ +N
Sbjct: 253 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVN 308
>gi|48928048 F-box and WD repeat domain containing 11 isoform A [Homo
sapiens]
Length = 508
Score = 90.9 bits (224), Expect = 1e-17
Identities = 62/230 (26%), Positives = 111/230 (48%), Gaps = 26/230 (11%)
Query: 1550 DKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECV 1609
D ++++++ S +C+ V GHT V CL + + TGSSD T+R ++V + E +
Sbjct: 225 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDER-----VIVTGSSDSTVRVWDVNTGEVL 279
Query: 1610 EQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGA 1669
L +H +L+ +NG +VT + ++ + +++ ++ L G
Sbjct: 280 NTL--------IHHNEAVLHLRFSNGLMVTCS--KDRSIAVWDMASATDIT-LRRVLVGH 328
Query: 1670 R----------KLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSD 1719
R K +V S D TI V +RTL GH + I C++ + LV SGSSD
Sbjct: 329 RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSD 388
Query: 1720 QSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQS 1769
++ +I G +R+ +GH V + K +V+ D ++V++LQ+
Sbjct: 389 NTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQA 438
Score = 62.0 bits (149), Expect = 5e-09
Identities = 51/202 (25%), Positives = 94/202 (46%), Gaps = 22/202 (10%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKV------NCLLVTQT 1582
GH +V +Q ++ T S+D TVRV+++ + + + H V N L+VT +
Sbjct: 244 GHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCS 303
Query: 1583 SGKNAALY--TGSSDHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTF 1640
++ A++ ++D T+R V R V + +D+ + S + T+ +
Sbjct: 304 KDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSAS---------GDRTIKVW 354
Query: 1641 NIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS 1700
+ + + H R ++CL + +L+V GS D TI + D G LR LEGH
Sbjct: 355 STSTCEFVRTLNGH-KRGIACL----QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHE 409
Query: 1701 KTILCMKVVNDLVFSGSSDQSV 1722
+ + C++ N + SG+ D +
Sbjct: 410 ELVRCIRFDNKRIVSGAYDGKI 431
Score = 57.8 bits (138), Expect = 1e-07
Identities = 39/171 (22%), Positives = 83/171 (48%), Gaps = 20/171 (11%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
GH+AAVN + + + S D+T++V++ + + + GH + CL ++
Sbjct: 327 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL-----QYRDRL 381
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQ-LEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKR 1647
+ +GSSD+TIR ++++ C+ L+ E+ V C+ + + +G +G + ++++
Sbjct: 382 VVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQ---- 437
Query: 1648 LEIFECHGPRAVSCLATAQEGARKL---------LVVGSYDCTISVRDARN 1689
+ P + CL T E + ++ ++ S+D TI + D N
Sbjct: 438 -AALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLN 487
Score = 43.9 bits (102), Expect = 0.001
Identities = 24/104 (23%), Positives = 52/104 (50%)
Query: 1699 HSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACL 1758
+SK + C++ ++ + SG D S+ + + E +++ GH +V + +V+VT
Sbjct: 205 NSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSS 264
Query: 1759 DKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSI 1802
D VRV+++ + + L H + ++ + ++ T D SI
Sbjct: 265 DSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSI 308
Score = 40.4 bits (93), Expect = 0.016
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+ GH+ + +Q L+ + S+D T+R++++ C+ V EGH V C+
Sbjct: 364 TLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF-----D 418
Query: 1586 NAALYTGSSDHTIRCYNVKS 1605
N + +G+ D I+ +++++
Sbjct: 419 NKRIVSGAYDGKIKVWDLQA 438
Score = 31.6 bits (70), Expect = 7.6
Identities = 12/56 (21%), Positives = 31/56 (55%)
Query: 1753 MVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQAVRLN 1808
+++ D +++++ S + L+V GH ++C+ + +I TG D +++ +N
Sbjct: 219 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVN 274
>gi|48928046 F-box and WD repeat domain containing 11 isoform B [Homo
sapiens]
Length = 529
Score = 90.9 bits (224), Expect = 1e-17
Identities = 62/230 (26%), Positives = 111/230 (48%), Gaps = 26/230 (11%)
Query: 1550 DKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECV 1609
D ++++++ S +C+ V GHT V CL + + TGSSD T+R ++V + E +
Sbjct: 246 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDER-----VIVTGSSDSTVRVWDVNTGEVL 300
Query: 1610 EQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGA 1669
L +H +L+ +NG +VT + ++ + +++ ++ L G
Sbjct: 301 NTL--------IHHNEAVLHLRFSNGLMVTCS--KDRSIAVWDMASATDIT-LRRVLVGH 349
Query: 1670 R----------KLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSD 1719
R K +V S D TI V +RTL GH + I C++ + LV SGSSD
Sbjct: 350 RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSD 409
Query: 1720 QSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQS 1769
++ +I G +R+ +GH V + K +V+ D ++V++LQ+
Sbjct: 410 NTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQA 459
Score = 62.0 bits (149), Expect = 5e-09
Identities = 51/202 (25%), Positives = 94/202 (46%), Gaps = 22/202 (10%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKV------NCLLVTQT 1582
GH +V +Q ++ T S+D TVRV+++ + + + H V N L+VT +
Sbjct: 265 GHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCS 324
Query: 1583 SGKNAALY--TGSSDHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTF 1640
++ A++ ++D T+R V R V + +D+ + S + T+ +
Sbjct: 325 KDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSAS---------GDRTIKVW 375
Query: 1641 NIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS 1700
+ + + H R ++CL + +L+V GS D TI + D G LR LEGH
Sbjct: 376 STSTCEFVRTLNGH-KRGIACL----QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHE 430
Query: 1701 KTILCMKVVNDLVFSGSSDQSV 1722
+ + C++ N + SG+ D +
Sbjct: 431 ELVRCIRFDNKRIVSGAYDGKI 452
Score = 57.8 bits (138), Expect = 1e-07
Identities = 39/171 (22%), Positives = 83/171 (48%), Gaps = 20/171 (11%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
GH+AAVN + + + S D+T++V++ + + + GH + CL ++
Sbjct: 348 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACL-----QYRDRL 402
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQ-LEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKR 1647
+ +GSSD+TIR ++++ C+ L+ E+ V C+ + + +G +G + ++++
Sbjct: 403 VVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQ---- 458
Query: 1648 LEIFECHGPRAVSCLATAQEGARKL---------LVVGSYDCTISVRDARN 1689
+ P + CL T E + ++ ++ S+D TI + D N
Sbjct: 459 -AALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLN 508
Score = 43.9 bits (102), Expect = 0.001
Identities = 24/104 (23%), Positives = 52/104 (50%)
Query: 1699 HSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACL 1758
+SK + C++ ++ + SG D S+ + + E +++ GH +V + +V+VT
Sbjct: 226 NSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSS 285
Query: 1759 DKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSI 1802
D VRV+++ + + L H + ++ + ++ T D SI
Sbjct: 286 DSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSI 329
Score = 40.4 bits (93), Expect = 0.016
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+ GH+ + +Q L+ + S+D T+R++++ C+ V EGH V C+
Sbjct: 385 TLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF-----D 439
Query: 1586 NAALYTGSSDHTIRCYNVKS 1605
N + +G+ D I+ +++++
Sbjct: 440 NKRIVSGAYDGKIKVWDLQA 459
Score = 31.6 bits (70), Expect = 7.6
Identities = 12/56 (21%), Positives = 31/56 (55%)
Query: 1753 MVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQAVRLN 1808
+++ D +++++ S + L+V GH ++C+ + +I TG D +++ +N
Sbjct: 240 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVN 295
>gi|45594312 TNF receptor-associated factor 7 [Homo sapiens]
Length = 670
Score = 87.8 bits (216), Expect = 9e-17
Identities = 77/316 (24%), Positives = 147/316 (46%), Gaps = 26/316 (8%)
Query: 1500 ISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIF--GNLLYTCSADKTVRVYN 1557
+S I N + S +G+F GHQ V + ++ G+LL++ S+DKT++V++
Sbjct: 365 LSHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWD 424
Query: 1558 -LVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQLED 1616
+ KC EGH V L + + LY+GS+D TI +++++ + V ++ D
Sbjct: 425 TCTTYKCQKTLEGHDGIVLALCI-----QGCKLYSGSADCTIIVWDIQNLQKVNTIRAHD 479
Query: 1617 RVLC-LHSRWRILYAGLANG----TVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARK 1671
+C L S +L++G +V +K K L H RA+ A+
Sbjct: 480 NPVCTLVSSHNVLFSGSLKAIKVWDIVGTELKLKKELTGLN-HWVRAL-------VAAQS 531
Query: 1672 LLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGE 1731
L GSY TI + D R + L+ ++ + V N + G+ + +H +I + E
Sbjct: 532 YLYSGSYQ-TIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIESKE 590
Query: 1732 LVRIYKGH---NHAVTVVNILGKVMV-TACLDKFVRVYELQSHDRLQVYGGHKDMIMCMT 1787
VR GH +A+ V++ + V +A D+ +RV+ + + Q H+ + +
Sbjct: 591 QVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALA 650
Query: 1788 IHKSMIYTGCYDGSIQ 1803
+ + +++G D +++
Sbjct: 651 VSRGRLFSGAVDSTVK 666
Score = 60.5 bits (145), Expect = 2e-08
Identities = 61/247 (24%), Positives = 112/247 (45%), Gaps = 19/247 (7%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+ EGH V A+ I G LY+ SAD T+ V+++ + + + H + V C LV+
Sbjct: 434 TLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPV-CTLVS----S 488
Query: 1586 NAALYTGSSDHTIRCYNVKSREC---VEQLQLEDRVLCLHSRWRILYAGLANGTVVTFNI 1642
+ L++GS I+ +++ E E L V L + LY+G + T+ ++I
Sbjct: 489 HNVLFSGSL-KAIKVWDIVGTELKLKKELTGLNHWVRALVAAQSYLYSG-SYQTIKIWDI 546
Query: 1643 KNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKT 1702
+ + + + G S T +V G+Y+ I V D + +RTL GH T
Sbjct: 547 RTLDCIHVLQTSGGSVYSIAVTNHH-----IVCGTYENLIHVWDIESKEQVRTLTGHVGT 601
Query: 1703 ILCMKVVN----DLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACL 1758
+ + V++ VFS S D+S+ ++ + H +VT + + + + +
Sbjct: 602 VYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSRGRLFSGAV 661
Query: 1759 DKFVRVY 1765
D V+V+
Sbjct: 662 DSTVKVW 668
>gi|4502477 beta-transducin repeat containing protein isoform 2 [Homo
sapiens]
Length = 569
Score = 86.7 bits (213), Expect = 2e-16
Identities = 61/228 (26%), Positives = 109/228 (47%), Gaps = 26/228 (11%)
Query: 1550 DKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECV 1609
D T+++++ + +C + GHT V CL + + TGSSD T+R ++V + E +
Sbjct: 286 DNTIKIWDKNTLECKRILTGHTGSVLCLQYDER-----VIITGSSDSTVRVWDVNTGEML 340
Query: 1610 EQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGA 1669
L +H +L+ NG +VT + ++ + +++ P ++ L G
Sbjct: 341 NTL--------IHHCEAVLHLRFNNGMMVTCS--KDRSIAVWDMASPTDIT-LRRVLVGH 389
Query: 1670 R----------KLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSD 1719
R K +V S D TI V + +RTL GH + I C++ + LV SGSSD
Sbjct: 390 RAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSD 449
Query: 1720 QSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYEL 1767
++ +I G +R+ +GH V + K +V+ D ++V++L
Sbjct: 450 NTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDL 497
Score = 63.2 bits (152), Expect = 2e-09
Identities = 65/264 (24%), Positives = 113/264 (42%), Gaps = 34/264 (12%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKV------NCLLVTQT 1582
GH +V +Q ++ T S+D TVRV+++ + + + H V N ++VT +
Sbjct: 305 GHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCS 364
Query: 1583 SGKNAALYTGSS--DHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTF 1640
++ A++ +S D T+R V R V + +D+ + S + T+ +
Sbjct: 365 KDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSAS---------GDRTIKVW 415
Query: 1641 NIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS 1700
N + + H R ++CL + +L+V GS D TI + D G LR LEGH
Sbjct: 416 NTSTCEFVRTLNGH-KRGIACL----QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHE 470
Query: 1701 KTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDK 1760
+ + C++ N + SG+ D + ++ R G T+V G
Sbjct: 471 ELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSG---------- 520
Query: 1761 FVRVYELQSHDRLQVYGGHKDMIM 1784
RV+ LQ + V H D I+
Sbjct: 521 --RVFRLQFDEFQIVSSSHDDTIL 542
Score = 59.7 bits (143), Expect = 3e-08
Identities = 41/171 (23%), Positives = 82/171 (47%), Gaps = 20/171 (11%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
GH+AAVN + + + S D+T++V+N + + + GH + CL ++
Sbjct: 388 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL-----QYRDRL 442
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQ-LEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKR 1647
+ +GSSD+TIR ++++ C+ L+ E+ V C+ + + +G +G + +++
Sbjct: 443 VVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDL----- 497
Query: 1648 LEIFECHGPRAVSCLATAQEGARKL---------LVVGSYDCTISVRDARN 1689
+ + P CL T E + ++ +V S+D TI + D N
Sbjct: 498 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLN 548
Score = 45.4 bits (106), Expect = 5e-04
Identities = 26/103 (25%), Positives = 51/103 (49%)
Query: 1700 SKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLD 1759
SK + C++ + + SG D ++ + +T E RI GH +V + +V++T D
Sbjct: 267 SKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSD 326
Query: 1760 KFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSI 1802
VRV+++ + + L H + ++ + + M+ T D SI
Sbjct: 327 STVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSI 369
Score = 39.7 bits (91), Expect = 0.028
Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+ GH+ + +Q L+ + S+D T+R++++ C+ V EGH V C+
Sbjct: 425 TLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF-----D 479
Query: 1586 NAALYTGSSDHTIRCYNV 1603
N + +G+ D I+ +++
Sbjct: 480 NKRIVSGAYDGKIKVWDL 497
>gi|16117783 beta-transducin repeat containing protein isoform 1 [Homo
sapiens]
Length = 605
Score = 86.7 bits (213), Expect = 2e-16
Identities = 61/228 (26%), Positives = 109/228 (47%), Gaps = 26/228 (11%)
Query: 1550 DKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECV 1609
D T+++++ + +C + GHT V CL + + TGSSD T+R ++V + E +
Sbjct: 322 DNTIKIWDKNTLECKRILTGHTGSVLCLQYDER-----VIITGSSDSTVRVWDVNTGEML 376
Query: 1610 EQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGA 1669
L +H +L+ NG +VT + ++ + +++ P ++ L G
Sbjct: 377 NTL--------IHHCEAVLHLRFNNGMMVTCS--KDRSIAVWDMASPTDIT-LRRVLVGH 425
Query: 1670 R----------KLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSD 1719
R K +V S D TI V + +RTL GH + I C++ + LV SGSSD
Sbjct: 426 RAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSD 485
Query: 1720 QSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYEL 1767
++ +I G +R+ +GH V + K +V+ D ++V++L
Sbjct: 486 NTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDL 533
Score = 63.2 bits (152), Expect = 2e-09
Identities = 65/264 (24%), Positives = 113/264 (42%), Gaps = 34/264 (12%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKV------NCLLVTQT 1582
GH +V +Q ++ T S+D TVRV+++ + + + H V N ++VT +
Sbjct: 341 GHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCS 400
Query: 1583 SGKNAALYTGSS--DHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTF 1640
++ A++ +S D T+R V R V + +D+ + S + T+ +
Sbjct: 401 KDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSAS---------GDRTIKVW 451
Query: 1641 NIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS 1700
N + + H R ++CL + +L+V GS D TI + D G LR LEGH
Sbjct: 452 NTSTCEFVRTLNGH-KRGIACL----QYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHE 506
Query: 1701 KTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDK 1760
+ + C++ N + SG+ D + ++ R G T+V G
Sbjct: 507 ELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSG---------- 556
Query: 1761 FVRVYELQSHDRLQVYGGHKDMIM 1784
RV+ LQ + V H D I+
Sbjct: 557 --RVFRLQFDEFQIVSSSHDDTIL 578
Score = 59.7 bits (143), Expect = 3e-08
Identities = 41/171 (23%), Positives = 82/171 (47%), Gaps = 20/171 (11%)
Query: 1529 GHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
GH+AAVN + + + S D+T++V+N + + + GH + CL ++
Sbjct: 424 GHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACL-----QYRDRL 478
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQ-LEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKR 1647
+ +GSSD+TIR ++++ C+ L+ E+ V C+ + + +G +G + +++
Sbjct: 479 VVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDL----- 533
Query: 1648 LEIFECHGPRAVSCLATAQEGARKL---------LVVGSYDCTISVRDARN 1689
+ + P CL T E + ++ +V S+D TI + D N
Sbjct: 534 VAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLN 584
Score = 45.4 bits (106), Expect = 5e-04
Identities = 26/103 (25%), Positives = 51/103 (49%)
Query: 1700 SKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLD 1759
SK + C++ + + SG D ++ + +T E RI GH +V + +V++T D
Sbjct: 303 SKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSD 362
Query: 1760 KFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSI 1802
VRV+++ + + L H + ++ + + M+ T D SI
Sbjct: 363 STVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSI 405
Score = 39.7 bits (91), Expect = 0.028
Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Query: 1526 SFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+ GH+ + +Q L+ + S+D T+R++++ C+ V EGH V C+
Sbjct: 461 TLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF-----D 515
Query: 1586 NAALYTGSSDHTIRCYNV 1603
N + +G+ D I+ +++
Sbjct: 516 NKRIVSGAYDGKIKVWDL 533
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 79.7 bits (195), Expect = 2e-14
Identities = 77/335 (22%), Positives = 149/335 (44%), Gaps = 32/335 (9%)
Query: 1459 STEQNPLETSRSGCDEVSSTSEIGTRYKDGIP-----VSVAETQTVISSIKGSKNSSEIS 1513
+TE+ ET + S+S ++ P ++A +SS+K S N ++
Sbjct: 2 ATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLA 61
Query: 1514 SEPGDD--------DEPTEGSFEGHQAAVNAI--QIFGNLLYTCSADKTVRVYNLVSRKC 1563
S D D E + GH+ ++ + NLL + S DKT++++++ S KC
Sbjct: 62 SSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKC 121
Query: 1564 IGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQL-EDRVLCLH 1622
+ +GH++ V C S + +GS D ++R ++VK+ +C++ L D V +H
Sbjct: 122 LKTLKGHSNYVFCCNFNPQSN---LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVH 178
Query: 1623 SR--WRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDC 1680
++ + +G ++ + + L+ VS + + G K ++ + D
Sbjct: 179 FNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG--KYILAATLDN 236
Query: 1681 TISVRDARNGLLLRTLEGHSKTILCM-----KVVNDLVFSGSSDQSVHAHNIHTGELVRI 1735
T+ + D G L+T GH C+ + SGS D V+ N+ T E+V+
Sbjct: 237 TLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQK 296
Query: 1736 YKGHNHAV--TVVNILGKVMVTACL--DKFVRVYE 1766
+GH V T + ++ +A L DK +++++
Sbjct: 297 LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331
Score = 65.1 bits (157), Expect = 6e-10
Identities = 77/371 (20%), Positives = 151/371 (40%), Gaps = 60/371 (16%)
Query: 1495 ETQTVISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIF--GNLLYTCSADKT 1552
ET+ + S ++++ P + + + GH AV++++ G L + SADK
Sbjct: 9 ETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKL 68
Query: 1553 VRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQL 1612
++++ K GH K+ V +S N L + S D T++ ++V S +C++ L
Sbjct: 69 IKIWGAYDGKFEKTISGH--KLGISDVAWSSDSNL-LVSASDDKTLKIWDVSSGKCLKTL 125
Query: 1613 QLEDR-VLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARK 1671
+ V C + FN ++N
Sbjct: 126 KGHSNYVFCCN-----------------FNPQSN-------------------------- 142
Query: 1672 LLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVND--LVFSGSSDQSVHAHNIHT 1729
L+V GS+D ++ + D + G L+TL HS + + D L+ S S D + +
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTAS 202
Query: 1730 GELVR-IYKGHNHAVTVVNIL--GKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCM 1786
G+ ++ + N V+ V GK ++ A LD +++++ L+ Y GHK+ C+
Sbjct: 203 GQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 1787 TIHKSM-----IYTGCYDGSIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNP 1841
+ S+ I +G D + L + + ++ H ++++
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALE 322
Query: 1842 NFQTLKCRWKN 1852
N +T+K WK+
Sbjct: 323 NDKTIKL-WKS 332
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 79.7 bits (195), Expect = 2e-14
Identities = 77/335 (22%), Positives = 149/335 (44%), Gaps = 32/335 (9%)
Query: 1459 STEQNPLETSRSGCDEVSSTSEIGTRYKDGIP-----VSVAETQTVISSIKGSKNSSEIS 1513
+TE+ ET + S+S ++ P ++A +SS+K S N ++
Sbjct: 2 ATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLA 61
Query: 1514 SEPGDD--------DEPTEGSFEGHQAAVNAI--QIFGNLLYTCSADKTVRVYNLVSRKC 1563
S D D E + GH+ ++ + NLL + S DKT++++++ S KC
Sbjct: 62 SSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKC 121
Query: 1564 IGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQL-EDRVLCLH 1622
+ +GH++ V C S + +GS D ++R ++VK+ +C++ L D V +H
Sbjct: 122 LKTLKGHSNYVFCCNFNPQSN---LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVH 178
Query: 1623 SR--WRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDC 1680
++ + +G ++ + + L+ VS + + G K ++ + D
Sbjct: 179 FNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG--KYILAATLDN 236
Query: 1681 TISVRDARNGLLLRTLEGHSKTILCM-----KVVNDLVFSGSSDQSVHAHNIHTGELVRI 1735
T+ + D G L+T GH C+ + SGS D V+ N+ T E+V+
Sbjct: 237 TLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQK 296
Query: 1736 YKGHNHAV--TVVNILGKVMVTACL--DKFVRVYE 1766
+GH V T + ++ +A L DK +++++
Sbjct: 297 LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331
Score = 65.1 bits (157), Expect = 6e-10
Identities = 77/371 (20%), Positives = 151/371 (40%), Gaps = 60/371 (16%)
Query: 1495 ETQTVISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIF--GNLLYTCSADKT 1552
ET+ + S ++++ P + + + GH AV++++ G L + SADK
Sbjct: 9 ETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKL 68
Query: 1553 VRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQL 1612
++++ K GH K+ V +S N L + S D T++ ++V S +C++ L
Sbjct: 69 IKIWGAYDGKFEKTISGH--KLGISDVAWSSDSNL-LVSASDDKTLKIWDVSSGKCLKTL 125
Query: 1613 QLEDR-VLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARK 1671
+ V C + FN ++N
Sbjct: 126 KGHSNYVFCCN-----------------FNPQSN-------------------------- 142
Query: 1672 LLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVND--LVFSGSSDQSVHAHNIHT 1729
L+V GS+D ++ + D + G L+TL HS + + D L+ S S D + +
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTAS 202
Query: 1730 GELVR-IYKGHNHAVTVVNIL--GKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCM 1786
G+ ++ + N V+ V GK ++ A LD +++++ L+ Y GHK+ C+
Sbjct: 203 GQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 1787 TIHKSM-----IYTGCYDGSIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNP 1841
+ S+ I +G D + L + + ++ H ++++
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALE 322
Query: 1842 NFQTLKCRWKN 1852
N +T+K WK+
Sbjct: 323 NDKTIKL-WKS 332
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 73.2 bits (178), Expect = 2e-12
Identities = 63/262 (24%), Positives = 117/262 (44%), Gaps = 23/262 (8%)
Query: 1500 ISSIKGSKNSSEISSEPGDD--------DEPTEGSFEGHQAAVNAI--QIFGNLLYTCSA 1549
+SS+K S N ++S D D E + GH ++ + + L + S
Sbjct: 44 VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103
Query: 1550 DKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECV 1609
DKT++++++ S KC+ +GH++ V C S + +GS D T++ + VK+ +C+
Sbjct: 104 DKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSN---LIISGSFDETVKIWEVKTGKCL 160
Query: 1610 EQLQL-EDRVLCLH--SRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQ 1666
+ L D V +H ++ +G +G ++ + + L+ VS + +
Sbjct: 161 KTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSP 220
Query: 1667 EGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCM-----KVVNDLVFSGSSDQS 1721
G K ++ + D T+ + D G L+T GH C+ + SGS D
Sbjct: 221 NG--KYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNL 278
Query: 1722 VHAHNIHTGELVRIYKGHNHAV 1743
V+ N+ T E+V+ +GH V
Sbjct: 279 VYIWNLQTKEIVQKLQGHTDVV 300
Score = 64.7 bits (156), Expect = 8e-10
Identities = 72/375 (19%), Positives = 154/375 (41%), Gaps = 59/375 (15%)
Query: 1491 VSVAETQTVISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIF--GNLLYTCS 1548
++ E++ + + S ++++ P + + + + GH AV++++ G L + S
Sbjct: 1 MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSS 60
Query: 1549 ADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSREC 1608
AD+ + ++ K GH +++ + + S + L + S D T++ ++V+S +C
Sbjct: 61 ADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSR---LVSASDDKTLKLWDVRSGKC 117
Query: 1609 VEQLQLEDR-VLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQE 1667
++ L+ V C + FN +N
Sbjct: 118 LKTLKGHSNYVFCCN-----------------FNPPSN---------------------- 138
Query: 1668 GARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCM--KVVNDLVFSGSSDQSVHAH 1725
L++ GS+D T+ + + + G L+TL HS + + L+ SGS D
Sbjct: 139 ----LIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIW 194
Query: 1726 NIHTGELVR-IYKGHNHAVTVVNIL--GKVMVTACLDKFVRVYELQSHDRLQVYGGHKDM 1782
+ +G+ ++ + N V+ V GK ++TA LD +++++ L+ Y GHK+
Sbjct: 195 DAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNE 254
Query: 1783 IMCMTIHKSM-----IYTGCYDGSIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTD 1837
C+ + S+ I +G D + L + + ++ H ++L+
Sbjct: 255 KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIAS 314
Query: 1838 HTNPNFQTLKCRWKN 1852
N +T+K N
Sbjct: 315 AALENDKTIKLWMSN 329
>gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens]
Length = 1051
Score = 67.4 bits (163), Expect = 1e-10
Identities = 47/214 (21%), Positives = 95/214 (44%), Gaps = 17/214 (7%)
Query: 1607 ECVEQLQLEDR-VLCLHSRWRILYAGLANGTVVTFN------IKNNKRLEIFECHGPRAV 1659
E +Q+ +E+R V C RIL V+ ++ + +N+++ + + +A+
Sbjct: 386 EETQQVLIEERNVFCGTYNVRILSDTWDQNRVIHYSGGDLIAVSSNRKIHLLDIIQVKAI 445
Query: 1660 SCLATAQEGA---------RKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVN 1710
G+ L+ GSYD +I D ++G+ R GH TI CM +
Sbjct: 446 PVEFRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCK 505
Query: 1711 DLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSH 1770
+ + SG D V ++ TG+ ++ ++ H + I +V++C V+V+ +
Sbjct: 506 NRLVSGGRDCQVKVWDVDTGKCLKTFR-HKDPILATRINDTYIVSSCERGLVKVWHIAMA 564
Query: 1771 DRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQA 1804
++ GH+ + C+ + + +G DG + A
Sbjct: 565 QLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMA 598
Score = 53.1 bits (126), Expect = 2e-06
Identities = 54/253 (21%), Positives = 103/253 (40%), Gaps = 55/253 (21%)
Query: 1527 FEGHQAAVNAIQIFG--NLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSG 1584
F GH +V A+ + N L + S D ++R ++L S C +F GH + C+ + +
Sbjct: 449 FRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNR- 507
Query: 1585 KNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKN 1644
L +G D ++ ++V + +C++ + +D +L + + G V ++I
Sbjct: 508 ----LVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHI-- 561
Query: 1645 NKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTIL 1704
A AQ L++TL GH +
Sbjct: 562 ------------------AMAQ-------------------------LVKTLSGHEGAVK 578
Query: 1705 CMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTV--VNILGKVMVTACLDKFV 1762
C+ + SGS+D V A ++ G+ R H V V++L +++AC D +
Sbjct: 579 CLFFDQWHLLSGSTDGLVMAWSM-VGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKI 637
Query: 1763 RVYELQSHDRLQV 1775
R+Y + + ++V
Sbjct: 638 RIYNFLNGNCMKV 650
>gi|157694487 CMT1A duplicated region transcript 1 [Homo sapiens]
Length = 752
Score = 67.4 bits (163), Expect = 1e-10
Identities = 47/214 (21%), Positives = 95/214 (44%), Gaps = 17/214 (7%)
Query: 1607 ECVEQLQLEDR-VLCLHSRWRILYAGLANGTVVTFN------IKNNKRLEIFECHGPRAV 1659
E +Q+ +E+R V C RIL V+ ++ + +N+++ + + +A+
Sbjct: 386 EETQQVLMEERNVFCGTYNVRILSDTWDQNRVIHYSGGDLIAVSSNRKIHLLDIIQVKAI 445
Query: 1660 SCLATAQEGA---------RKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVN 1710
G+ L+ GSYD +I D ++G+ R GH TI CM +
Sbjct: 446 PVEFRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCK 505
Query: 1711 DLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSH 1770
+ + SG D V ++ TG+ ++ ++ H + I +V++C V+V+ +
Sbjct: 506 NRLVSGGRDCQVKVWDVDTGKCLKTFR-HKDPILATRINDTYIVSSCERGLVKVWHIAMA 564
Query: 1771 DRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQA 1804
++ GH+ + C+ + + +G DG + A
Sbjct: 565 QLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMA 598
Score = 53.5 bits (127), Expect = 2e-06
Identities = 58/273 (21%), Positives = 110/273 (40%), Gaps = 57/273 (20%)
Query: 1527 FEGHQAAVNAIQIFG--NLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSG 1584
F GH +V A+ + N L + S D ++R ++L S C +F GH + C+ + +
Sbjct: 449 FRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNR- 507
Query: 1585 KNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKN 1644
L +G D ++ ++V + +C++ + +D +L + + G V ++I
Sbjct: 508 ----LVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHI-- 561
Query: 1645 NKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTIL 1704
A AQ L++TL GH +
Sbjct: 562 ------------------AMAQ-------------------------LVKTLSGHEGAVK 578
Query: 1705 CMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTV--VNILGKVMVTACLDKFV 1762
C+ + SGS+D V A ++ G+ R H V V++L +++AC D +
Sbjct: 579 CLFFDQWHLLSGSTDGLVMAWSM-VGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKI 637
Query: 1763 RVYELQSHDRLQVY--GGHKDMIMCMTIHKSMI 1793
R+Y + + ++V G D ++ I + I
Sbjct: 638 RIYNFFNGNCMKVIKANGRGDPVLSFFIQGNRI 670
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 66.6 bits (161), Expect = 2e-10
Identities = 61/277 (22%), Positives = 114/277 (41%), Gaps = 45/277 (16%)
Query: 1524 EGSFEGHQAAVNAIQI--FGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQ 1581
E + +GH +V I G LL +CSAD T+++++ +CI GH V+ + +
Sbjct: 143 ERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMP 202
Query: 1582 TSGKNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTFN 1641
+ + S D TI+ + V++ CV + H W + +GT++ +
Sbjct: 203 NGDH---IVSASRDKTIKMWEVQTGYCV-------KTFTGHREWVRMVRPNQDGTLIA-S 251
Query: 1642 IKNNKRLEIF-----ECHG-----PRAVSCLATAQEGARK------------------LL 1673
N++ + ++ EC V C++ A E + L
Sbjct: 252 CSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFL 311
Query: 1674 VVGSYDCTISVRDARNGLLLRTLEGHSKTI--LCMKVVNDLVFSGSSDQSVHAHNIHTGE 1731
+ GS D TI + D G+ L TL GH + + + S + D+++ +
Sbjct: 312 LSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKR 371
Query: 1732 LVRIYKGHNHAVTVVNI--LGKVMVTACLDKFVRVYE 1766
++ H H VT ++ +VT +D+ V+V+E
Sbjct: 372 CMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/116 (29%), Positives = 64/116 (55%), Gaps = 4/116 (3%)
Query: 1672 LLVVGSYDCTISVRDARNGLLLRTLEGHSKTI--LCMKVVNDLVFSGSSDQSVHAHNIHT 1729
++V S D TI V D G RTL+GH+ ++ + L+ S S+D ++ +
Sbjct: 122 VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 181
Query: 1730 GELVRIYKGHNHAVTVVNIL--GKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMI 1783
E +R GH+H V+ V I+ G +V+A DK ++++E+Q+ ++ + GH++ +
Sbjct: 182 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWV 237
Score = 37.7 bits (86), Expect = 0.11
Identities = 21/97 (21%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 1696 LEGHSKTI--LCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNI--LGK 1751
L GH + + V ++ S S D ++ + TG+ R KGH +V ++ GK
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 1752 VMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTI 1788
++ + D +++++ Q + ++ GH + + I
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAI 200
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 66.2 bits (160), Expect = 3e-10
Identities = 84/337 (24%), Positives = 135/337 (40%), Gaps = 61/337 (18%)
Query: 1449 DSPSKKDI----WNSTEQNPLETSRSGCDEVSSTSEIGTRYKDG-IPVSVAETQTVISSI 1503
D PS KD+ WNS E + + I T KDG + ++ + + I ++
Sbjct: 221 DVPSNKDVTSLDWNS------EGTLLATGSYDGFARIWT--KDGNLASTLGQHKGPIFAL 272
Query: 1504 KGSKNSSEISSEPGDDDE--------PTEGSFEGHQA-AVNAIQIFGNLLYTCSADKTVR 1554
K +K + I S D + F H A A++ N +CS D +
Sbjct: 273 KWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIH 332
Query: 1555 VYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQL 1614
V L + I F+GHT++VN + T L + S D T++ +++K CV LQ
Sbjct: 333 VCKLGQDRPIKTFQGHTNEVNAIKWDPTGN---LLASCSDDMTLKIWSMKQDNCVHDLQA 389
Query: 1615 EDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLV 1674
++ + + I ++ GT + P A LA+A
Sbjct: 390 HNKEI-----YTIKWSPTGPGT-----------------NNPNANLMLASA--------- 418
Query: 1675 VGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVND--LVFSGSSDQSVHAHNIHTGEL 1732
S+D T+ + D G+ + TL H + + + D + SGS D+ VH N TG L
Sbjct: 419 --SFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGAL 476
Query: 1733 VRIYKGHNHAVTVV-NILGKVMVTACLDKFVRVYELQ 1768
V Y+G V N G + + D V V +L+
Sbjct: 477 VHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLR 513
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 63.5 bits (153), Expect = 2e-09
Identities = 53/203 (26%), Positives = 87/203 (42%), Gaps = 13/203 (6%)
Query: 1527 FEGHQAAVNAIQIF--GNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSG 1584
F H A V ++ G T S DKTV+V+ +K + H + V C + S
Sbjct: 61 FRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRC---AKFSP 117
Query: 1585 KNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLC---LHSRWRILYAGLANGTVVTFN 1641
+ + S D T++ ++ SRECV + H + A + TV ++
Sbjct: 118 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 177
Query: 1642 IKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS- 1700
++ ++ L+ ++ H AV+ L+ G L+ S D T+ + D G LL TL GH
Sbjct: 178 VRTHRLLQHYQLHS-AAVNGLSFHPSG--NYLITASSDSTLKILDLMEGRLLYTLHGHQG 234
Query: 1701 -KTILCMKVVNDLVFSGSSDQSV 1722
T + + SG SD+ V
Sbjct: 235 PATTVAFSRTGEYFASGGSDEQV 257
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 63.5 bits (153), Expect = 2e-09
Identities = 53/203 (26%), Positives = 87/203 (42%), Gaps = 13/203 (6%)
Query: 1527 FEGHQAAVNAIQIF--GNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSG 1584
F H A V ++ G T S DKTV+V+ +K + H + V C + S
Sbjct: 99 FRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRC---AKFSP 155
Query: 1585 KNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLC---LHSRWRILYAGLANGTVVTFN 1641
+ + S D T++ ++ SRECV + H + A + TV ++
Sbjct: 156 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215
Query: 1642 IKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS- 1700
++ ++ L+ ++ H AV+ L+ G L+ S D T+ + D G LL TL GH
Sbjct: 216 VRTHRLLQHYQLHS-AAVNGLSFHPSG--NYLITASSDSTLKILDLMEGRLLYTLHGHQG 272
Query: 1701 -KTILCMKVVNDLVFSGSSDQSV 1722
T + + SG SD+ V
Sbjct: 273 PATTVAFSRTGEYFASGGSDEQV 295
Score = 38.5 bits (88), Expect = 0.063
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 1732 LVRIYKGHNHAVTVVN--ILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIH 1789
L R +KGH AVT V+ I K + + +D + V+ ++ R + GHKD + C+
Sbjct: 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFS 70
Query: 1790 KS--MIYTGCYDGSIQ 1803
S ++ +G D +++
Sbjct: 71 PSGHLLASGSRDKTVR 86
Score = 32.0 bits (71), Expect = 5.9
Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 4/97 (4%)
Query: 1687 ARNGLLLRTLEGHSKTILCM--KVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVT 1744
A + L R +GH + C+ + + SGS D + ++ + GH AVT
Sbjct: 6 AEDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVT 65
Query: 1745 VVNI--LGKVMVTACLDKFVRVYELQSHDRLQVYGGH 1779
VN G ++ + DK VR++ V+ H
Sbjct: 66 CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAH 102
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 63.5 bits (153), Expect = 2e-09
Identities = 53/203 (26%), Positives = 87/203 (42%), Gaps = 13/203 (6%)
Query: 1527 FEGHQAAVNAIQIF--GNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSG 1584
F H A V ++ G T S DKTV+V+ +K + H + V C + S
Sbjct: 99 FRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRC---AKFSP 155
Query: 1585 KNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLC---LHSRWRILYAGLANGTVVTFN 1641
+ + S D T++ ++ SRECV + H + A + TV ++
Sbjct: 156 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215
Query: 1642 IKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS- 1700
++ ++ L+ ++ H AV+ L+ G L+ S D T+ + D G LL TL GH
Sbjct: 216 VRTHRLLQHYQLHS-AAVNGLSFHPSG--NYLITASSDSTLKILDLMEGRLLYTLHGHQG 272
Query: 1701 -KTILCMKVVNDLVFSGSSDQSV 1722
T + + SG SD+ V
Sbjct: 273 PATTVAFSRTGEYFASGGSDEQV 295
Score = 38.5 bits (88), Expect = 0.063
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 1732 LVRIYKGHNHAVTVVN--ILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIH 1789
L R +KGH AVT V+ I K + + +D + V+ ++ R + GHKD + C+
Sbjct: 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFS 70
Query: 1790 KS--MIYTGCYDGSIQ 1803
S ++ +G D +++
Sbjct: 71 PSGHLLASGSRDKTVR 86
Score = 32.0 bits (71), Expect = 5.9
Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 4/97 (4%)
Query: 1687 ARNGLLLRTLEGHSKTILCM--KVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVT 1744
A + L R +GH + C+ + + SGS D + ++ + GH AVT
Sbjct: 6 AEDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVT 65
Query: 1745 VVNI--LGKVMVTACLDKFVRVYELQSHDRLQVYGGH 1779
VN G ++ + DK VR++ V+ H
Sbjct: 66 CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAH 102
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 60.8 bits (146), Expect = 1e-08
Identities = 116/582 (19%), Positives = 220/582 (37%), Gaps = 97/582 (16%)
Query: 1278 NSPSSQSAGLSSINKEGEEPTKGNSGSEACTSSFLRLSFASETPLEKE----------PH 1327
NSP S+ + LSS + K + + T++ + L +A + L + P
Sbjct: 1114 NSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPL 1173
Query: 1328 SPADQPEQQAESTLTSAETRGSKKKKKLRKKKSLRAAHVPENSDTEQDVLTVKPVRKVKA 1387
+P + ++ +T TS + K+ S + ++S +E+ + PV + KA
Sbjct: 1174 TPVAEGQEIGMNTETSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKA 1233
Query: 1388 GKLIKGGKVTTSTWEDSRTGREQESVRDEPDSDSSLEVLEIPNPQLEVVAIDSSESGEEK 1447
+ + K DS T S P S P +L V + G
Sbjct: 1234 YEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSR--------PRNELNVFNRLTVSQGN-- 1283
Query: 1448 PDSPSKKDIWNSTEQNPLETSRSGCDEVSSTSEIGTRYKDGIPVSVAETQTVISSIKGSK 1507
S +Q+ + S S EV +S G +I+ SK
Sbjct: 1284 ----------TSVQQDKSDESDSSLSEVHRSSRRG----------------IINPFPASK 1317
Query: 1508 NSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVF 1567
+ EGH AV + +LL+T S D+T +V+NLV+ + I
Sbjct: 1318 GIRAFPLQ-------CIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSL 1370
Query: 1568 EGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVK-SRECVEQLQLEDRV-------- 1618
GH + V + + + ++T S+ + I+ ++++ S +C+ L +V
Sbjct: 1371 GGHPNNV---VSVKYCNYTSLVFTVSTSY-IKVWDIRDSAKCIRTLTSSGQVTLGDACSA 1426
Query: 1619 -----------------LCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECH-GPRAVS 1660
+ L+ LYA N V +++K + H GP V
Sbjct: 1427 STSRTVAIPSGENQINQIALNPTGTFLYAASGN-AVRMWDLKRFQSTGKLTGHLGP--VM 1483
Query: 1661 CLATAQ-EGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS------KTILCMKVVNDLV 1713
CL Q + L++ GS D I + D G L H+ I + + D +
Sbjct: 1484 CLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNL 1543
Query: 1714 FSGSSDQSVHAHNIHTGELV-RIYKGHNHAVTVVNIL--GKVMVTACLDKFVRVYELQSH 1770
FSGS D + ++ +L+ ++ H V + ++ V+++ C ++V+ + +
Sbjct: 1544 FSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTF 1603
Query: 1771 DRLQVYGGHKDMIMCMTIHKSMIYTGCYDGSIQAVRLNLMQN 1812
+ GH I + ++ + I+T D +++ + +Q+
Sbjct: 1604 MPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQD 1645
Score = 37.4 bits (85), Expect = 0.14
Identities = 118/595 (19%), Positives = 230/595 (38%), Gaps = 78/595 (13%)
Query: 524 QKQSGDNLNDTLRKAKEV-LQCHESLQNPLLSTSKSTRNYAKASRNVEESEKGSLKIEFQ 582
+KQ + L K ++ L+ + LQN L S + AK R+ E + ++ E Q
Sbjct: 662 KKQYEEKLMMLQHKIRDTQLERDQVLQN-LGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 720
Query: 583 -VHALEDESDGETSDTEKHGTKIGTLGSATTELLSGSTRTAD---EKEEDDRILKTSREL 638
+ A + E + ++ ++ L E+ R E++E R+ ++ R
Sbjct: 721 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 780
Query: 639 STSPCNPIVRQKESELQMTSAASPHPGLLLDLKT-------------------------S 673
+ R+++ +L++ A + ++L KT S
Sbjct: 781 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 840
Query: 674 LEDAQVDDSIKSHVSYETEGFESASLDAELQKSDISQPSGPLLPELSKLGFPASLQRD-L 732
DA D+ S + ET+ AS QK I LP + G QR L
Sbjct: 841 SSDAPAQDTGSSAAAVETD----ASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGL 896
Query: 733 TRHISLKSKTGVHLPEPNLNSARRIRNISGHRKSETEKESGLKPTLRQILNASRRNVNWE 792
T + + SKT + L RR+ +I + + + E+ + L+Q ++R
Sbjct: 897 TGRVFI-SKTA-RMKWQLLE--RRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLS 952
Query: 793 QVIQQVTKKKQELGKGLPRFGIEMVPLVQNEQEALD--LDGEPDLSSLEGFQWEGVSISS 850
+ +++ K+ E K + EM L N D D + ++ +E + EG ++
Sbjct: 953 KRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDV 1012
Query: 851 SPGLARKRSLSESSVIMDRAPSVYSFFSEEGTGKENEPQQM---VSPSNSLRAGQSQKAT 907
+ + +L+E+ ++D S+ + KE + + + + + A Q+Q
Sbjct: 1013 T-AVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLF 1071
Query: 908 MHLKQ--EVTPRAASLRTGERAENVATQRRHSAQLSSDHIIPL-------MHLAKDLNSQ 958
LK+ E+ P +L G +++ + + + S+D PL L+ DL
Sbjct: 1072 HMLKEKAELNPELDAL-LGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKL 1130
Query: 959 ERSIPPSENQNSQESNGEGNCLSSSASSALAISSLADAATDSSCTSGAE--------QND 1010
+ P +N+ + + + L + +S + +S DA+ T AE +
Sbjct: 1131 CGEVKP-KNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETS 1189
Query: 1011 GQSIRKKRRATGDGSSPELPSLERKNK-------------RRKIKGKKERSQVDQ 1052
G S R+K + G ++ S+ R++ RRK K E+S+ +
Sbjct: 1190 GTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKE 1244
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 58.2 bits (139), Expect = 8e-08
Identities = 56/289 (19%), Positives = 113/289 (39%), Gaps = 35/289 (12%)
Query: 1529 GHQAAVNAIQIFG-NLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNA 1587
GH++ V + N+ +A +++++N + +CI T L + +
Sbjct: 413 GHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCI-----RTMTCEYALCSFFVPGDR 467
Query: 1588 ALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLCLHSR------------------WRILY 1629
+ G+ ++ Y++ S +E + D L S W
Sbjct: 468 QVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFEL 527
Query: 1630 AGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARN 1689
N T ++K + L++ E L + +KLL V DCT+ +
Sbjct: 528 VKDENSTQKRLSVKQTRTLQLDE-------DVLCVSYSPNQKLLAVSLLDCTVKIFYVDT 580
Query: 1690 GLLLRTLEGHSKTILCMKVVND--LVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVN 1747
+L GH ++CM + +D L+ +GS+D++V + G+ + H+ +V +
Sbjct: 581 LKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQ 640
Query: 1748 ILGK--VMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHKSMIY 1794
+ K + TA D ++ ++ + +Q GH I C+ + S Y
Sbjct: 641 FVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDY 689
Score = 33.9 bits (76), Expect = 1.5
Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 4/106 (3%)
Query: 1682 ISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFS--GSSDQSVHAHNIHTGELVRIYKGH 1739
+ + D R G + L+G + + C+ D + G D S+ ++ +GE + GH
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 1740 NHAVTVVNI--LGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMI 1783
A+T + LG + + D + V+++ + L GHKD I
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAI 152
Score = 33.1 bits (74), Expect = 2.6
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 1528 EGHQAAVNAIQIFG--NLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGK 1585
+GH+ A+ NLL T D V+ ++L ++ C GH ++V L++ +
Sbjct: 146 KGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLL---SE 202
Query: 1586 NAALYTGSSDHTIRCYNVKSRECVEQLQLED 1616
L TG+SD +R +++ + +E + D
Sbjct: 203 EKRLITGASDSELRVWDIAYLQEIEDPEEPD 233
>gi|153791298 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 58.2 bits (139), Expect = 8e-08
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 23/222 (10%)
Query: 1531 QAAVNAIQ--IFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
Q AV A++ + GN TC +DKT++++N + + + GH +V L S N++
Sbjct: 25 QGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEV---LDAAGSFDNSS 81
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQ---LEDRVLCLHSRWRILYAGLANGTVVTFNIKNN 1645
L +G D + ++V S + V + + + + + ++ +G + ++ ++ ++
Sbjct: 82 LCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSR 141
Query: 1646 KRLEIFECHGPRAVSCLATAQEGARKL------LVVGSYDCTISVRDARNGLLLRTLEGH 1699
+ P V L A++G + ++ GS D + D R G L G
Sbjct: 142 R---------PEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVGS 192
Query: 1700 SKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNH 1741
T C S D ++ + TGEL+ YKGH +
Sbjct: 193 PITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKN 234
Score = 57.0 bits (136), Expect = 2e-07
Identities = 57/216 (26%), Positives = 101/216 (46%), Gaps = 17/216 (7%)
Query: 1526 SFEGHQAAV-NAIQIFGNL-LYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTS 1583
++ GH V +A F N L + DK V ++++ S + + F GH KVN Q +
Sbjct: 62 TYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVN---TVQFN 118
Query: 1584 GKNAALYTGSSDHTIRCYNVKSR--ECVEQL-QLEDRVLCLHSRWRILYAGLANGTVVTF 1640
+ + +GS D +IRC++ +SR E V+ L + D V + + AG +G V +
Sbjct: 119 EEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRY 178
Query: 1641 NIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS 1700
+++ ++F + ++C +++G + +V S D T+ + D G LL +GH
Sbjct: 179 DLRMG---QLFSDYVGSPITCTCFSRDG--QCTLVSSLDSTLRLLDKDTGELLGEYKGHK 233
Query: 1701 ----KTILCMKVVNDLVFSGSSDQSVHAHNIHTGEL 1732
K C+ + V S S D V ++ G L
Sbjct: 234 NQEYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGAL 269
>gi|14150114 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 58.2 bits (139), Expect = 8e-08
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 23/222 (10%)
Query: 1531 QAAVNAIQ--IFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAA 1588
Q AV A++ + GN TC +DKT++++N + + + GH +V L S N++
Sbjct: 25 QGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEV---LDAAGSFDNSS 81
Query: 1589 LYTGSSDHTIRCYNVKSRECVEQLQ---LEDRVLCLHSRWRILYAGLANGTVVTFNIKNN 1645
L +G D + ++V S + V + + + + + ++ +G + ++ ++ ++
Sbjct: 82 LCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSR 141
Query: 1646 KRLEIFECHGPRAVSCLATAQEGARKL------LVVGSYDCTISVRDARNGLLLRTLEGH 1699
+ P V L A++G + ++ GS D + D R G L G
Sbjct: 142 R---------PEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVGS 192
Query: 1700 SKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELVRIYKGHNH 1741
T C S D ++ + TGEL+ YKGH +
Sbjct: 193 PITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKN 234
Score = 57.0 bits (136), Expect = 2e-07
Identities = 57/216 (26%), Positives = 101/216 (46%), Gaps = 17/216 (7%)
Query: 1526 SFEGHQAAV-NAIQIFGNL-LYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTS 1583
++ GH V +A F N L + DK V ++++ S + + F GH KVN Q +
Sbjct: 62 TYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVN---TVQFN 118
Query: 1584 GKNAALYTGSSDHTIRCYNVKSR--ECVEQL-QLEDRVLCLHSRWRILYAGLANGTVVTF 1640
+ + +GS D +IRC++ +SR E V+ L + D V + + AG +G V +
Sbjct: 119 EEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRY 178
Query: 1641 NIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS 1700
+++ ++F + ++C +++G + +V S D T+ + D G LL +GH
Sbjct: 179 DLRMG---QLFSDYVGSPITCTCFSRDG--QCTLVSSLDSTLRLLDKDTGELLGEYKGHK 233
Query: 1701 ----KTILCMKVVNDLVFSGSSDQSVHAHNIHTGEL 1732
K C+ + V S S D V ++ G L
Sbjct: 234 NQEYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGAL 269
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 56.2 bits (134), Expect = 3e-07
Identities = 61/279 (21%), Positives = 112/279 (40%), Gaps = 61/279 (21%)
Query: 1526 SFEGHQAAVNAIQIF--GNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTS 1583
+ +GH AV + G++L++ S DKTV V++ + + + +GHTS VN +
Sbjct: 104 TLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRG 163
Query: 1584 GKNAALYTGSSDHTIRCYNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIK 1643
+ + TGS D T++ ++++ + ++ Q +VL VTFN
Sbjct: 164 PQ--LVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVL-----------------AVTFNDT 204
Query: 1644 NNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTI 1703
+++ ++ G D I V D R L T+ GH+ ++
Sbjct: 205 SDQ--------------------------IISGGIDNDIKVWDLRQNKLTYTMRGHADSV 238
Query: 1704 --LCMKVVNDLVFSGSSDQSVHAHNIH----TGELVRIYKGHNHAVTVVNIL-------G 1750
L + + S + D +V ++ V+I++G+ H N+L G
Sbjct: 239 TGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFE-KNLLRCSWSPDG 297
Query: 1751 KVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIH 1789
+ D+FV V++ S L GH I + H
Sbjct: 298 SKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFH 336
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/210 (24%), Positives = 89/210 (42%), Gaps = 14/210 (6%)
Query: 1530 HQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAAL 1589
HQ A+ G +LY S + VR++ L + +G GH V CL VTQT+ ++ +
Sbjct: 1400 HQINQIALSPSGTMLYAASGN-AVRIWELSRFQPVGKLTGHIGPVMCLTVTQTASQHDLV 1458
Query: 1590 YTGSSDHTIRCYNVKSRECVE---------QLQLEDRVLCLHSRWRILYAGLANGTVVTF 1640
TGS DH ++ + + ECV + D + CL + IL++G + + +
Sbjct: 1459 VTGSKDHYVKMFEL--GECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKW 1516
Query: 1641 NIKNNKRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHS 1700
++ + ++ V LA R +L+ I V + N + ++GH
Sbjct: 1517 DLDQQELIQQIPNAHKDWVCALAFIP--GRPMLLSACRAGVIKVWNVDNFTPIGEIKGHD 1574
Query: 1701 KTILCMKVVNDLVFSGSSDQSVHAHNIHTG 1730
I + +F+ SSD V N G
Sbjct: 1575 SPINAICTNAKHIFTASSDCRVKLWNYVPG 1604
Score = 52.4 bits (124), Expect = 4e-06
Identities = 66/309 (21%), Positives = 123/309 (39%), Gaps = 44/309 (14%)
Query: 1528 EGHQAAVNAIQIFGNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNA 1587
EGH + + LL+T S D++ +++NLV+ + I +GH + V + SG
Sbjct: 1292 EGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCSHSG--- 1348
Query: 1588 ALYTGSSDHTIRCYNVK-SRECVEQLQLEDRV-------------------------LCL 1621
L S I+ ++++ S +C+ L +V + L
Sbjct: 1349 -LVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVISGDACAATSTRAITSAQGEHQINQIAL 1407
Query: 1622 HSRWRILYAGLANGTVVTFNIKNNKRLEIFECH-GPRAVSCLATAQEGAR-KLLVVGSYD 1679
+LYA N V + + + + H GP V CL Q ++ L+V GS D
Sbjct: 1408 SPSGTMLYAASGN-AVRIWELSRFQPVGKLTGHIGP--VMCLTVTQTASQHDLVVTGSKD 1464
Query: 1680 CTISVRDARN------GLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHNIHTGELV 1733
+ + + G H I C+ + D++FSGS D + ++ EL+
Sbjct: 1465 HYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWDLDQQELI 1524
Query: 1734 -RIYKGHNHAVTVVNIL--GKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIMCMTIHK 1790
+I H V + + ++++AC ++V+ + + + GH I + +
Sbjct: 1525 QQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTPIGEIKGHDSPINAICTNA 1584
Query: 1791 SMIYTGCYD 1799
I+T D
Sbjct: 1585 KHIFTASSD 1593
Score = 44.3 bits (103), Expect = 0.001
Identities = 54/285 (18%), Positives = 111/285 (38%), Gaps = 56/285 (19%)
Query: 1562 KCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQ-----LED 1616
+C+ + EGHT + CL T + L+TGS D + + +N+ + + + L+ +
Sbjct: 1286 QCVSMAEGHTKPILCLDAT-----DELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVS 1340
Query: 1617 RVLCLHSRWRILYAGLANGTVVTFNIKNNKRL----------------------EIFECH 1654
C HS L ++ + ++I+++ + I
Sbjct: 1341 IKYCSHSG---LVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVISGDACAATSTRAITSAQ 1397
Query: 1655 GPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVV----- 1709
G ++ +A + G G+ + + + + L GH ++C+ V
Sbjct: 1398 GEHQINQIALSPSGTMLYAASGN---AVRIWELSRFQPVGKLTGHIGPVMCLTVTQTASQ 1454
Query: 1710 NDLVFSGSSDQSVHAHNIHTGELVRIYKGHNH--------AVTVVNILGKVMVTACLDKF 1761
+DLV +GS D V + GE V G H + + I G ++ + D
Sbjct: 1455 HDLVVTGSKDHYVKMFEL--GECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNG 1512
Query: 1762 VRVYELQSHDRL-QVYGGHKDMIMCMTI--HKSMIYTGCYDGSIQ 1803
++ ++L + + Q+ HKD + + + M+ + C G I+
Sbjct: 1513 IKKWDLDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIK 1557
Score = 31.2 bits (69), Expect = 10.0
Identities = 41/208 (19%), Positives = 78/208 (37%), Gaps = 28/208 (13%)
Query: 1607 ECVEQLQLEDR-VLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATA 1665
+CV + + +LCL + +L+ G + + +N+ + + + H VS +
Sbjct: 1286 QCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCS 1345
Query: 1666 QEGARKLLVVGSYDCTISVRDARNGL-LLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHA 1724
G LV I V D R+ +RTL + I SG + +
Sbjct: 1346 HSG----LVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVI-----------SGDACAATST 1390
Query: 1725 HNIHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIM 1784
I + + G + + M+ A VR++EL + GH +M
Sbjct: 1391 RAITSAQ------GEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHIGPVM 1444
Query: 1785 CMTIHKS-----MIYTGCYDGSIQAVRL 1807
C+T+ ++ ++ TG D ++ L
Sbjct: 1445 CLTVTQTASQHDLVVTGSKDHYVKMFEL 1472
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 55.1 bits (131), Expect = 6e-07
Identities = 61/289 (21%), Positives = 112/289 (38%), Gaps = 46/289 (15%)
Query: 1436 VAIDSSESGEEKPDSPSKKDIWNSTEQNPLETSRSGCDEVSSTSEIGTRYKDGIPVSVAE 1495
+ +D S E P+ P++K + + EQN +T G + S P+ +
Sbjct: 276 IKVDHSREKENAPEGPTQKGLREAREQNKCKTKMKGNTKDSE-----------FPIDMQP 324
Query: 1496 TQTVISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAI--QIFGNLLYTCSADKTV 1553
+ N S+ S P D + F H+ V+ + Q ++L +C D+
Sbjct: 325 NPNL--------NVSKESLSPAKFDYKLKNIFRLHELPVSCVSMQPHKDILVSCGEDRLW 376
Query: 1554 RVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVEQLQ 1613
+V L + GHT ++ + K L T S D T++ +++ +C+ +
Sbjct: 377 KVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDK---LATSSGDTTVKLWDLCKGDCILTFE 433
Query: 1614 LEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGARKL- 1672
R + W + N + K +K I++ + R L + +
Sbjct: 434 GHSRAV-----WSCTWHSCGNFVASSSLDKTSK---IWDVNSERCRCTLYGHTDSVNSIE 485
Query: 1673 -------LVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVF 1714
L+ S D T+S+ DAR G+ ++L GH M +ND +F
Sbjct: 486 FFPFSNTLLTSSADKTLSIWDARTGICEQSLYGH------MHSINDAIF 528
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 54.7 bits (130), Expect = 8e-07
Identities = 44/171 (25%), Positives = 85/171 (49%), Gaps = 9/171 (5%)
Query: 1646 KRLEIFECHGPRAVSCLATAQEGARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILC 1705
+R++ F HG V+ A + +G ++L+ GS D + + R+G LL L GH+ +
Sbjct: 12 RRVKFFGQHGGE-VNSSAFSPDG--QMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKF 68
Query: 1706 MKVVND--LVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNIL--GKVMVTACLDKF 1761
+ D L S S D +V ++ + +R+ KGH +V V+ + + + DK
Sbjct: 69 CRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKR 128
Query: 1762 VRVYELQSHDRLQVYGGHKDMIMCMTIHKSM--IYTGCYDGSIQAVRLNLM 1810
V ++++QS L++ GH+D I ++ + TG +D ++ L ++
Sbjct: 129 VMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMV 179
Score = 51.2 bits (121), Expect = 9e-06
Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 49/203 (24%)
Query: 1541 GNLLYTCSADKTVRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRC 1600
G+L + S D TVR++++ KC+ V +GH V + + S + L +G D +
Sbjct: 75 GHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQ---LASGGWDKRVML 131
Query: 1601 YNVKSRECVEQLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVS 1660
++V+S + + R+L H R I V+
Sbjct: 132 WDVQSGQML-------RLLVGH------------------------RDSIQSSDFSPTVN 160
Query: 1661 CLATAQEGARKLLVVGSYDCTISVRDAR---NGLLLRTLEGHSKTILCM-KVVNDLVFSG 1716
CLAT GS+D T+ + D R + + LEGHS I C+ + L+ SG
Sbjct: 161 CLAT-----------GSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASGLLASG 209
Query: 1717 SSDQSVHAHNIHTGELVRIYKGH 1739
S D+++H T L+ KGH
Sbjct: 210 SWDKTIHIWKPTTSSLLIQLKGH 232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,659,257
Number of Sequences: 37866
Number of extensions: 3831206
Number of successful extensions: 19955
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 639
Number of HSP's that attempted gapping in prelim test: 16485
Number of HSP's gapped (non-prelim): 3670
length of query: 1883
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1766
effective length of database: 13,817,196
effective search space: 24401168136
effective search space used: 24401168136
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.