Guide to the Human Genome
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Search of human proteins with 119395727

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]         809   0.0  
gi|227430327 calsequestrin 1 [Homo sapiens]                           548   e-156
gi|4758304 protein disulfide isomerase A4 [Homo sapiens]               62   1e-09
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul...    58   2e-08
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s...    52   1e-06
gi|42740903 MTERF domain containing 2 [Homo sapiens]                   48   2e-05
gi|55956788 nucleolin [Homo sapiens]                                   48   2e-05
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      47   3e-05
gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]    47   4e-05
gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens]    47   4e-05
gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens]    47   4e-05
gi|38505222 thioredoxin domain containing 10 [Homo sapiens]            46   7e-05
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    44   2e-04
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    44   3e-04
gi|115529449 upstream binding transcription factor, RNA polymera...    44   3e-04
gi|115529451 upstream binding transcription factor, RNA polymera...    44   3e-04
gi|7657671 upstream binding transcription factor, RNA polymerase...    44   3e-04
gi|18093112 ABT1-associated protein [Homo sapiens]                     44   3e-04
gi|4757900 calreticulin precursor [Homo sapiens]                       44   3e-04
gi|51477718 TATA box binding protein-associated factor, RNA poly...    44   3e-04
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]                   43   4e-04
gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]                   43   4e-04
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]                   43   4e-04
gi|91598939 secreted phosphoprotein 1 isoform c [Homo sapiens]         43   4e-04
gi|91206462 secreted phosphoprotein 1 isoform a [Homo sapiens]         42   7e-04
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       42   7e-04
gi|19924161 RPB5-mediating protein isoform b [Homo sapiens]            42   7e-04
gi|19924159 RPB5-mediating protein isoform a [Homo sapiens]            42   7e-04
gi|21735415 centromere protein B [Homo sapiens]                        42   0.001
gi|16445033 ACRC protein [Homo sapiens]                                42   0.001

>gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]
          Length = 399

 Score =  809 bits (2089), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MKRTHLFIVGIYFLSSCRAEEGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPV 60
           MKRTHLFIVGIYFLSSCRAEEGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPV
Sbjct: 1   MKRTHLFIVGIYFLSSCRAEEGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPV 60

Query: 61  SSDKVTQKQFQLKEIVLELVAQVLEHKAIGFVMVDAKKEAKLAKKLGFDEEGSLYILKGD 120
           SSDKVTQKQFQLKEIVLELVAQVLEHKAIGFVMVDAKKEAKLAKKLGFDEEGSLYILKGD
Sbjct: 61  SSDKVTQKQFQLKEIVLELVAQVLEHKAIGFVMVDAKKEAKLAKKLGFDEEGSLYILKGD 120

Query: 121 RTIEFDGEFAADVLVEFLLDLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYK 180
           RTIEFDGEFAADVLVEFLLDLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYK
Sbjct: 121 RTIEFDGEFAADVLVEFLLDLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYK 180

Query: 181 AFEEAAEHFQPYIKFFATFDKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEF 240
           AFEEAAEHFQPYIKFFATFDKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEF
Sbjct: 181 AFEEAAEHFQPYIKFFATFDKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEF 240

Query: 241 VKEHQRPTLRRLRPEEMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPD 300
           VKEHQRPTLRRLRPEEMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPD
Sbjct: 241 VKEHQRPTLRRLRPEEMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPD 300

Query: 301 LSILWIDPDDFPLLVAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELED 360
           LSILWIDPDDFPLLVAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELED
Sbjct: 301 LSILWIDPDDFPLLVAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELED 360

Query: 361 WIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           WIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE
Sbjct: 361 WIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399


>gi|227430327 calsequestrin 1 [Homo sapiens]
          Length = 396

 Score =  548 bits (1412), Expect = e-156
 Identities = 251/367 (68%), Positives = 316/367 (86%)

Query: 15  SSCRAEEGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVTQKQFQLKE 74
           S  + +EGL+FP YDG DRV++++ KN+K V KKY++L L YHEP   DK +Q+QF+++E
Sbjct: 30  SGVQGQEGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMEE 89

Query: 75  IVLELVAQVLEHKAIGFVMVDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVL 134
           ++LEL AQVLE K +GF +VD++K+A +AKKLG  E  S+Y+ KGD  IE+DGEF+AD +
Sbjct: 90  LILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVIEYDGEFSADTI 149

Query: 135 VEFLLDLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIK 194
           VEFLLD++EDPVE+I  + E+QAFE IED IKLIG+FKS+DSE+YKAFE+AAE F PYI 
Sbjct: 150 VEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIP 209

Query: 195 FFATFDKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEFVKEHQRPTLRRLRP 254
           FFATFD  VAKKL+LK+NE+DFYE FM+EP+ IP+KP +EEE+V FV+EH+R TLR+L+P
Sbjct: 210 FFATFDSKVAKKLTLKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKP 269

Query: 255 EEMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLL 314
           E M+ETWEDD++GIHIVAFAE++DPDG+EFLE LK VA+DNT+NPDLSI+WIDPDDFPLL
Sbjct: 270 ESMYETWEDDMDGIHIVAFAEEADPDGFEFLETLKAVAQDNTENPDLSIIWIDPDDFPLL 329

Query: 315 VAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTED 374
           V YWEKTF IDL  PQIGVVNVTDADSVWME+ D++DLP+AEELEDW+EDVL G+INTED
Sbjct: 330 VPYWEKTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTED 389

Query: 375 DDEDDDD 381
           DD+DDDD
Sbjct: 390 DDDDDDD 396


>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
          Length = 645

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 45/186 (24%), Positives = 89/186 (47%), Gaps = 10/186 (5%)

Query: 37  LSEKNFKQVLKKYDLLCLYYHEPVSSD-KVTQKQFQLKEIVLELVAQVLEHKA--IGFVM 93
           L+++NF +V+   D++ + ++ P     K    ++       E  A+ L  ++  I    
Sbjct: 182 LTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEY-------EKAAKELSKRSPPIPLAK 234

Query: 94  VDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVLVEFLLDLIEDPVEIISSKL 153
           VDA  E  LAK+       +L I +  R  +++G      +V+++++    P + I +  
Sbjct: 235 VDATAETDLAKRFDVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTLK 294

Query: 154 EVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIKFFATFDKGVAKKLSLKMNE 213
           +VQ F +  D + +IG FK E    Y+ +++AA + +   KF  TF   +AK L +   +
Sbjct: 295 QVQEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAKFLKVSQGQ 354

Query: 214 VDFYEP 219
           +   +P
Sbjct: 355 LVVMQP 360



 Score = 37.0 bits (84), Expect = 0.031
 Identities = 60/281 (21%), Positives = 115/281 (40%), Gaps = 31/281 (11%)

Query: 34  VVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVTQKQFQLKEIVLELVAQVLEHK--AIGF 91
           V+ L++ NF   +   D + L ++ P        KQF  +    E +A +L+ K   I  
Sbjct: 64  VLVLNDANFDNFVADKDTVLLEFYAPWCGHC---KQFAPE---YEKIANILKDKDPPIPV 117

Query: 92  VMVDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVLVEFLLDLIE---DPVEI 148
             +DA   + LA +       ++ ILK  + ++++G    + +V  + ++ +    P   
Sbjct: 118 AKIDATSASVLASRFDVSGYPTIKILKKGQAVDYEGSRTQEEIVAKVREVSQPDWTPPPE 177

Query: 149 ISSKLEVQAFER---------IEDYIKLIGFFKSEDSEYYKAFEEAAEHFQ--PYIKFFA 197
           ++  L  + F+          +E Y    G  K    EY KA +E ++     P  K  A
Sbjct: 178 VTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDA 237

Query: 198 TFDKGVAKKLSLKMNEVDFYEPFMDEPIAIP---NKPYTEEELVEFVKEHQRPTLRR-LR 253
           T +  +AK+      +V  Y          P   N P  +  +V+++ E   P  +  L 
Sbjct: 238 TAETDLAKRF-----DVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILT 292

Query: 254 PEEMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARD 294
            +++ E  +D  + I I  F  +SDP   ++ +    +  D
Sbjct: 293 LKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLRED 333



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 10/27 (37%), Positives = 19/27 (70%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           E  DED  + +N+ E++ ++ ++DDDE
Sbjct: 25  EGPDEDSSNRENAIEDEEEEEEEDDDE 51


>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
           [Homo sapiens]
          Length = 406

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 73/363 (20%), Positives = 150/363 (41%), Gaps = 21/363 (5%)

Query: 34  VVSLSEKNFKQVLKKYDL-LCLYYHEPVSSDKVTQKQFQLKEIVLELVAQVLEHKAIGFV 92
           + SL  +N  ++L   D+ L  +Y +     ++    F+    V++   +      + F 
Sbjct: 31  ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIK--EEFPNENQVVFA 88

Query: 93  MVDAKKEAKLAKKLGFDEEGSLYILKGDRTI--EFDGEFAADVLVEFLLDLIEDPVEIIS 150
            VD  + + +A++    +  +L + +    +  E+ G+ +   L +++     DP++ I 
Sbjct: 89  RVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIR 148

Query: 151 SKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIKFFATFDKGVAKKLSLK 210
              E+   +R +  I  IG+F+ +DS+ Y+ FE  A        F + F   V+K     
Sbjct: 149 DLAEITTLDRSKRNI--IGYFEQKDSDNYRVFERVANILHDDCAFLSAFG-DVSKPERYS 205

Query: 211 MNEVDFYEPFMDEPIAIPNKPYTEEELV-EFVKEHQRPTLRRLRPEEMFETWEDDLNGIH 269
            + + +  P    P  +     T  ++   ++++   P +R +  E   E  E+ L    
Sbjct: 206 GDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLP--F 263

Query: 270 IVAFAEKSDPDGYEFLEILKQVARD-NTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFR 328
           ++ F  K D +  E  +   +VAR   ++   ++ L  D D F   + + +KT       
Sbjct: 264 LILFHMKEDTESLEIFQ--NEVARQLISEKGTINFLHADCDKFRHPLLHIQKT------- 314

Query: 329 PQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEE 388
           P    V   D+        D  D+    +L+ ++ D+ SGK++ E     D  D    E+
Sbjct: 315 PADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQ 374

Query: 389 DND 391
             D
Sbjct: 375 AQD 377


>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
           sapiens]
          Length = 508

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 86/370 (23%), Positives = 145/370 (39%), Gaps = 39/370 (10%)

Query: 31  KDRVVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVTQKQFQLKEIVLELVAQVLEHKAIG 90
           +D V+ L + NF + L  +  L + ++ P             K +  E      + KA G
Sbjct: 23  EDHVLVLRKSNFAEALAAHKYLLVEFYAPWCG--------HCKALAPEYAKAAGKLKAEG 74

Query: 91  ----FVMVDAKKEAKLAKKLGFDEEGSLYILKGDRTI---EFDGEFAADVLVEFLLDLIE 143
                  VDA +E+ LA++ G     ++   +   T    E+     AD +V +L     
Sbjct: 75  SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG 134

Query: 144 DPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIKFFATFDKGV 203
                +      ++     + + +IGFFK  +S+  K F +AAE     I F  T +  V
Sbjct: 135 PAATTLPDGAAAESLVESSE-VAVIGFFKDVESDSAKQFLQAAEAIDD-IPFGITSNSDV 192

Query: 204 AKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEFVKEHQRPTLRRLRPEEMFETWED 263
             K  L  + V  ++ F DE         T+E L++F+K +Q P +     +   + +  
Sbjct: 193 FSKYQLDKDGVVLFKKF-DEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGG 251

Query: 264 DLNGIHIVAFAEKSDPDGYEFLEILKQVAR-------------DNTDNPD-LSILWIDPD 309
           ++   HI+ F  KS  D    L   K  A              D+TDN   L    +  +
Sbjct: 252 EIK-THILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKE 310

Query: 310 DFPL--LVAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIED--- 364
           + P   L+   E+  K      ++    +T+    ++E      L + E  EDW +    
Sbjct: 311 ECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVK 370

Query: 365 VLSGKINTED 374
           VL GK N ED
Sbjct: 371 VLVGK-NFED 379


>gi|42740903 MTERF domain containing 2 [Homo sapiens]
          Length = 381

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 20/45 (44%), Positives = 31/45 (68%)

Query: 355 AEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           A E E+        K  + D+DEDDDD++++DE+DND+ DDD+D+
Sbjct: 321 AREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDD 365



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 24/52 (46%), Positives = 35/52 (67%), Gaps = 5/52 (9%)

Query: 349 DDDLPTAEELEDWIEDVLSGKINTEDD-DEDDDDDDNSDEEDNDDSDDDDDE 399
           DD   + +E ED  ++    + N EDD DEDDDD+D+ + EDND+ +DDD+E
Sbjct: 333 DDKRASLDEDEDDDDE----EDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEE 380



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 15/43 (34%), Positives = 28/43 (65%)

Query: 356 EELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDD 398
           EE E    D     ++ ++DD+D++D+D  D +++DD +DDD+
Sbjct: 325 EESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDE 367



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 6/44 (13%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDE--DDDDDDNSDEED 389
           D+DD    ++ ED  ED      + EDDDE  D+D+D++ DEE+
Sbjct: 342 DEDD----DDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDD 383
           E  DDDD    +E ++  +D        ED+DED+DDD+
Sbjct: 341 EDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDE 379


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 17/27 (62%), Positives = 25/27 (92%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           E+DDED+DDDD+ D+ED+DD DD+++E
Sbjct: 239 EEDDEDEDDDDDEDDEDDDDEDDEEEE 265



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 16/27 (59%), Positives = 25/27 (92%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           ED++EDD+D+D+ D+ED++D DD+DDE
Sbjct: 236 EDEEEDDEDEDDDDDEDDEDDDDEDDE 262



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 12/64 (18%)

Query: 348 DDDDLPTAEELEDWIEDV------------LSGKINTEDDDEDDDDDDNSDEEDNDDSDD 395
           DDDD    +  E+ +E              +  K   ED+DE++DD+D  D++D DD DD
Sbjct: 197 DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256

Query: 396 DDDE 399
           DD++
Sbjct: 257 DDED 260



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 20/52 (38%), Positives = 30/52 (57%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           D++D    +E ED IE             ED+DD+D+ D+ED+DD ++DD E
Sbjct: 156 DEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSE 207



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 16/27 (59%), Positives = 22/27 (81%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           ED DE++DDD   DEED++D D+D+DE
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDE 169



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 15/37 (40%), Positives = 28/37 (75%)

Query: 363 EDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           ++V   +   EDD+++DDDDD  DE+D+D+ D++++E
Sbjct: 230 KNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE 266



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 3/62 (4%)

Query: 338 DADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDD 397
           D DS   E  D+D+    +E+E       +    +ED+D++DD+D   DE+D+DD +DD 
Sbjct: 150 DDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED---DEDDDDDEEDDS 206

Query: 398 DE 399
           +E
Sbjct: 207 EE 208



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 13/29 (44%), Positives = 24/29 (82%)

Query: 371 NTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           N + +D D+++DD+S+E++ DD D+D+DE
Sbjct: 139 NAKKEDSDEEEDDDSEEDEEDDEDEDEDE 167



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 17/61 (27%)

Query: 356 EELEDWIEDVLSGKINTEDDDEDDDDD-----------------DNSDEEDNDDSDDDDD 398
           +E  D  ED  S +   +D+DED+D+D                 D  DE+D DD DDDDD
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201

Query: 399 E 399
           E
Sbjct: 202 E 202



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 12/27 (44%), Positives = 24/27 (88%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           EDDD+D+DD+D+ DE+D ++ +++++E
Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEEEE 271



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 11/27 (40%), Positives = 24/27 (88%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           ++D++DDDD+D+ D++D DD +++++E
Sbjct: 242 DEDEDDDDDEDDEDDDDEDDEEEEEEE 268



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 11/27 (40%), Positives = 24/27 (88%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           ED+D+DDD+DD  D++++D+ +++++E
Sbjct: 243 EDEDDDDDEDDEDDDDEDDEEEEEEEE 269



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 12/37 (32%), Positives = 29/37 (78%)

Query: 363 EDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           ED    + + ++DD+DD+DD++ D+ED+++ +++++E
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEE 270



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 15/38 (39%), Positives = 25/38 (65%)

Query: 357 ELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSD 394
           E ED  ED      + ++DDEDDDD+D+ +EE+ ++ +
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEE 271



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 8/47 (17%)

Query: 346 IPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDD 392
           + +D+D    +E ED  +D        EDD++DDD+DD  +EE+ ++
Sbjct: 232 VAEDEDEEEDDEDEDDDDD--------EDDEDDDDEDDEEEEEEEEE 270


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 27/77 (35%), Positives = 44/77 (57%), Gaps = 9/77 (11%)

Query: 331 IGVVNVTDADSVWM-------EIPDDDDLPTAEELEDWIEDVLSGKINT-EDDDEDDDDD 382
           +GV N T+  ++ M       +I   D+  T +  E  +E    G+    EDD ED+DD+
Sbjct: 205 LGVFNETEESNLNMYTRGKQKDIQRTDE-ETTDNQEGSVESSEEGEDQEHEDDGEDEDDE 263

Query: 383 DNSDEEDNDDSDDDDDE 399
           D+ D++D+DD DDD+D+
Sbjct: 264 DDDDDDDDDDDDDDEDD 280



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 20/51 (39%), Positives = 34/51 (66%)

Query: 349 DDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           +  + ++EE ED   +      + EDDD+DDDDDD+ D+ED++D +D ++E
Sbjct: 239 EGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEE 289



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 13/27 (48%), Positives = 23/27 (85%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           +DDD+DDDDDD+ D+ED +D ++++ +
Sbjct: 266 DDDDDDDDDDDDEDDEDEEDGEEENQK 292



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 14/42 (33%), Positives = 25/42 (59%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEED 389
           +D +     E ED  +D      + +DDDEDD+D+++ +EE+
Sbjct: 249 EDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEEN 290


>gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)

Query: 319 EKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDED 378
           E+  K D++   +    V D D       DDDD    +E E+ +ED+  G    ED+ E+
Sbjct: 228 EEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGD---EDEGEE 284

Query: 379 DDDDDNSDEEDNDDSDDD 396
           D+DDD  +E + D+ +DD
Sbjct: 285 DEDDDEGEEGEEDEGEDD 302



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query: 340 DSVWME------IPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDS 393
           D +W        +PD DD    E+ +D  +D   G+   ED DE D+D+   DE+D++  
Sbjct: 233 DDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGE 292

Query: 394 DDDDDE 399
           + ++DE
Sbjct: 293 EGEEDE 298


>gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)

Query: 319 EKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDED 378
           E+  K D++   +    V D D       DDDD    +E E+ +ED+  G    ED+ E+
Sbjct: 228 EEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGD---EDEGEE 284

Query: 379 DDDDDNSDEEDNDDSDDD 396
           D+DDD  +E + D+ +DD
Sbjct: 285 DEDDDEGEEGEEDEGEDD 302



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query: 340 DSVWME------IPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDS 393
           D +W        +PD DD    E+ +D  +D   G+   ED DE D+D+   DE+D++  
Sbjct: 233 DDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGE 292

Query: 394 DDDDDE 399
           + ++DE
Sbjct: 293 EGEEDE 298


>gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)

Query: 319 EKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDED 378
           E+  K D++   +    V D D       DDDD    +E E+ +ED+  G    ED+ E+
Sbjct: 228 EEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGD---EDEGEE 284

Query: 379 DDDDDNSDEEDNDDSDDD 396
           D+DDD  +E + D+ +DD
Sbjct: 285 DEDDDEGEEGEEDEGEDD 302



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query: 340 DSVWME------IPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDS 393
           D +W        +PD DD    E+ +D  +D   G+   ED DE D+D+   DE+D++  
Sbjct: 233 DDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGE 292

Query: 394 DDDDDE 399
           + ++DE
Sbjct: 293 EGEEDE 298


>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
          Length = 454

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 58/299 (19%), Positives = 125/299 (41%), Gaps = 22/299 (7%)

Query: 84  LEHKAIGFVM----VDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVLVEFLL 139
           LE K+IG  +    +DA   + +A + G     ++ +LKGD    + G    D ++EF  
Sbjct: 68  LEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAH 127

Query: 140 DLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIKFFATF 199
            +    +  + S+   Q FE ++   ++   +   +S   + + +AA     Y  FF+  
Sbjct: 128 RVSGALIRPLPSQ---QMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSAS 184

Query: 200 DKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEFVKEHQRPTLRRLRPEEMFE 259
           ++ V + ++LK  E+     F DE   + ++ Y + +L  ++   +      +    ++E
Sbjct: 185 EEVVPEYVTLK--EMPAVLVFKDETYFVYDE-YEDGDLSSWINRERFQNYLAMDGFLLYE 241

Query: 260 TWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTD--NPDLSILWIDPDDFPLLVAY 317
             +        V   + +  +      I+++VARD  D  + D     +D +D      Y
Sbjct: 242 LGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGND------Y 295

Query: 318 WEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDD 376
                  +L  P + V+N ++     +    D  +   E++  +I ++L G +  +  D
Sbjct: 296 INTLLMDELTVPTVVVLNTSNQQYFLL----DRQIKNVEDMVQFINNILDGTVEAQGGD 350


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 15/27 (55%), Positives = 23/27 (85%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           EDDD+D+DDDD  DEE+ ++ ++DDD+
Sbjct: 140 EDDDDDEDDDDEEDEEEEEEEEEDDDD 166



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 15/26 (57%), Positives = 23/26 (88%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDD 398
           +DDDEDDDD+++ +EE+ ++ DDDDD
Sbjct: 142 DDDDEDDDDEEDEEEEEEEEEDDDDD 167



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 13/27 (48%), Positives = 23/27 (85%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           +DDD++DDDD+  +EE+ ++ +DDDD+
Sbjct: 141 DDDDDEDDDDEEDEEEEEEEEEDDDDD 167



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 14/31 (45%), Positives = 24/31 (77%)

Query: 369 KINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           K + +DD++DDD++D  +EE+ ++ DDDD E
Sbjct: 139 KEDDDDDEDDDDEEDEEEEEEEEEDDDDDTE 169



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 11/27 (40%), Positives = 22/27 (81%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           +D+D+DD++D+  +EE+ +D DDD ++
Sbjct: 144 DDEDDDDEEDEEEEEEEEEDDDDDTED 170



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 12/26 (46%), Positives = 21/26 (80%)

Query: 374 DDDEDDDDDDNSDEEDNDDSDDDDDE 399
           D  E+DD +D+ D+ED+DD +D+++E
Sbjct: 132 DGGEEDDKEDDDDDEDDDDEEDEEEE 157



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 13/35 (37%), Positives = 24/35 (68%)

Query: 363 EDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDD 397
           ED      + EDDD+++D+++  +EE++DD D +D
Sbjct: 136 EDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTED 170



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 10/27 (37%), Positives = 23/27 (85%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           +DD+ED+++++  +E+D+DD++D  D+
Sbjct: 148 DDDEEDEEEEEEEEEDDDDDTEDFADQ 174



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 9/51 (17%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDD 398
           DDDD    ++ ED  E         E+++E+DDDDD  D  D ++  D  D
Sbjct: 141 DDDDDEDDDDEEDEEE---------EEEEEEDDDDDTEDFADQENLPDPQD 182



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 10/27 (37%), Positives = 19/27 (70%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           E   +  ++DD  D++D++D DD++DE
Sbjct: 128 EPGGDGGEEDDKEDDDDDEDDDDEEDE 154


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 17/39 (43%), Positives = 29/39 (74%)

Query: 359  EDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDD 397
            ED  E++   +   EDD+++DDD+D+ DE+D++D DD+D
Sbjct: 1676 EDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDED 1714



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 15/25 (60%), Positives = 23/25 (92%)

Query: 374  DDDEDDDDDDNSDEEDNDDSDDDDD 398
            +DDED+DDD++ D+ED+D+ DDD+D
Sbjct: 1690 EDDEDEDDDEDDDDEDDDEDDDDED 1714



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 14/27 (51%), Positives = 23/27 (85%)

Query: 373  EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
            E+ ++D+D+DD+ D++D DD +DDDDE
Sbjct: 1687 EEAEDDEDEDDDEDDDDEDDDEDDDDE 1713



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 8/71 (11%)

Query: 329  PQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEE 388
            P+ G      A     +  ++++L   EE  +  ED        EDDDEDDDD+D+ +++
Sbjct: 1659 PREGAAAAAAAAGESSQEDEEEELELPEEEAEDDED--------EDDDEDDDDEDDDEDD 1710

Query: 389  DNDDSDDDDDE 399
            D++D   D +E
Sbjct: 1711 DDEDLRTDSEE 1721



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 16/50 (32%), Positives = 31/50 (62%), Gaps = 9/50 (18%)

Query: 344  MEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDS 393
            +E+P+++    AE+ ED  +D      + +D+D+D+DDDD     D+++S
Sbjct: 1682 LELPEEE----AEDDEDEDDDE-----DDDDEDDDEDDDDEDLRTDSEES 1722


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 21/53 (39%), Positives = 35/53 (66%), Gaps = 1/53 (1%)

Query: 348 DDDDLPTAEELEDWIEDVL-SGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           D+D+    +E  D  ED   S + ++ED+ ED D+++  DE+++DD DDD+DE
Sbjct: 652 DEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE 704



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 16/34 (47%), Positives = 24/34 (70%)

Query: 366 LSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           L  K  +E+DDE+D+DD++ DEE+ DD + D  E
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE 667



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 19/55 (34%), Positives = 33/55 (60%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           E  DD+D    EE ++  +    G  ++E   ED+ +D + +EED++D DDD+D+
Sbjct: 646 EDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 700



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 16/54 (29%), Positives = 34/54 (62%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDD 398
           E  DD++  ++E+  D  E     +    D++E+DD+D++ DE+D++D D++ +
Sbjct: 656 EEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 12/27 (44%), Positives = 22/27 (81%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           EDD+ED+DD+D  +EE++D++ D  ++
Sbjct: 642 EDDEEDEDDEDEDEEEEDDENGDSSED 668



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 16/53 (30%)

Query: 359 EDWIEDVLSGKINTEDDDEDDDDDDNSDEEDN-------------DDSDDDDD 398
           ED  ED   G  N EDD+++DDD+D+ ++EDN             D SD D +
Sbjct: 678 EDESED---GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 8/55 (14%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           E   +D+    +E E+  ED        EDDDEDDD+D++++ E +  S     +
Sbjct: 674 ESSSEDESEDGDENEEDDED--------EDDDEDDDEDEDNESEGSSSSSSSSGD 720



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 23/69 (33%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDD--------------DDDDNSDEEDN 390
           E  +DD+    +E ED  E         EDD+  D              D+ ++ DE + 
Sbjct: 639 ESEEDDEEDEDDEDEDEEE---------EDDENGDSSEDGGDSSESSSEDESEDGDENEE 689

Query: 391 DDSDDDDDE 399
           DD D+DDDE
Sbjct: 690 DDEDEDDDE 698



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 13/50 (26%), Positives = 26/50 (52%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDD 397
           D  +  + +E ED  E+    +   +D+D+D+D+D+ S+   +  S   D
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 21/53 (39%), Positives = 35/53 (66%), Gaps = 1/53 (1%)

Query: 348 DDDDLPTAEELEDWIEDVL-SGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           D+D+    +E  D  ED   S + ++ED+ ED D+++  DE+++DD DDD+DE
Sbjct: 652 DEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE 704



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 16/34 (47%), Positives = 24/34 (70%)

Query: 366 LSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           L  K  +E+DDE+D+DD++ DEE+ DD + D  E
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE 667



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 19/55 (34%), Positives = 33/55 (60%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           E  DD+D    EE ++  +    G  ++E   ED+ +D + +EED++D DDD+D+
Sbjct: 646 EDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 700



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 16/54 (29%), Positives = 34/54 (62%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDD 398
           E  DD++  ++E+  D  E     +    D++E+DD+D++ DE+D++D D++ +
Sbjct: 656 EEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 12/27 (44%), Positives = 22/27 (81%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           EDD+ED+DD+D  +EE++D++ D  ++
Sbjct: 642 EDDEEDEDDEDEDEEEEDDENGDSSED 668



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 16/53 (30%)

Query: 359 EDWIEDVLSGKINTEDDDEDDDDDDNSDEEDN-------------DDSDDDDD 398
           ED  ED   G  N EDD+++DDD+D+ ++EDN             D SD D +
Sbjct: 678 EDESED---GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 8/55 (14%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           E   +D+    +E E+  ED        EDDDEDDD+D++++ E +  S     +
Sbjct: 674 ESSSEDESEDGDENEEDDED--------EDDDEDDDEDEDNESEGSSSSSSSSGD 720



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 23/69 (33%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDD--------------DDDDNSDEEDN 390
           E  +DD+    +E ED  E         EDD+  D              D+ ++ DE + 
Sbjct: 639 ESEEDDEEDEDDEDEDEEE---------EDDENGDSSEDGGDSSESSSEDESEDGDENEE 689

Query: 391 DDSDDDDDE 399
           DD D+DDDE
Sbjct: 690 DDEDEDDDE 698



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 13/50 (26%), Positives = 26/50 (52%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDD 397
           D  +  + +E ED  E+    +   +D+D+D+D+D+ S+   +  S   D
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 720


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 21/53 (39%), Positives = 35/53 (66%), Gaps = 1/53 (1%)

Query: 348 DDDDLPTAEELEDWIEDVL-SGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           D+D+    +E  D  ED   S + ++ED+ ED D+++  DE+++DD DDD+DE
Sbjct: 689 DEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE 741



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 16/34 (47%), Positives = 24/34 (70%)

Query: 366 LSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           L  K  +E+DDE+D+DD++ DEE+ DD + D  E
Sbjct: 671 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE 704



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 19/55 (34%), Positives = 33/55 (60%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           E  DD+D    EE ++  +    G  ++E   ED+ +D + +EED++D DDD+D+
Sbjct: 683 EDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 737



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 16/54 (29%), Positives = 34/54 (62%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDD 398
           E  DD++  ++E+  D  E     +    D++E+DD+D++ DE+D++D D++ +
Sbjct: 693 EEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 12/27 (44%), Positives = 22/27 (81%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           EDD+ED+DD+D  +EE++D++ D  ++
Sbjct: 679 EDDEEDEDDEDEDEEEEDDENGDSSED 705



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 16/53 (30%)

Query: 359 EDWIEDVLSGKINTEDDDEDDDDDDNSDEEDN-------------DDSDDDDD 398
           ED  ED   G  N EDD+++DDD+D+ ++EDN             D SD D +
Sbjct: 715 EDESED---GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 8/55 (14%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           E   +D+    +E E+  ED        EDDDEDDD+D++++ E +  S     +
Sbjct: 711 ESSSEDESEDGDENEEDDED--------EDDDEDDDEDEDNESEGSSSSSSSSGD 757



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 23/69 (33%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDD--------------DDDDNSDEEDN 390
           E  +DD+    +E ED  E         EDD+  D              D+ ++ DE + 
Sbjct: 676 ESEEDDEEDEDDEDEDEEE---------EDDENGDSSEDGGDSSESSSEDESEDGDENEE 726

Query: 391 DDSDDDDDE 399
           DD D+DDDE
Sbjct: 727 DDEDEDDDE 735



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 13/50 (26%), Positives = 26/50 (52%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDD 397
           D  +  + +E ED  E+    +   +D+D+D+D+D+ S+   +  S   D
Sbjct: 708 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGD 757


>gi|18093112 ABT1-associated protein [Homo sapiens]
          Length = 851

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 23/86 (26%), Positives = 48/86 (55%), Gaps = 7/86 (8%)

Query: 319 EKTFKIDLFRPQIGVVNVTDADSVWMEIPDDD-----DLPTAEELEDWIEDVLSGKINTE 373
           +   ++ + R   G  N TD +    +  ++D     ++ + EE E+ I  V  G+ + +
Sbjct: 211 QSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEESENEITSV--GRASGD 268

Query: 374 DDDEDDDDDDNSDEEDNDDSDDDDDE 399
           DD  +DD++++ DEE+++D D +DD+
Sbjct: 269 DDGSEDDEEEDEDEEEDEDEDSEDDD 294


>gi|4757900 calreticulin precursor [Homo sapiens]
          Length = 417

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 40/170 (23%), Positives = 69/170 (40%), Gaps = 42/170 (24%)

Query: 259 ETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPD-------DF 311
           E W+++++G        + +P   +  E   +      DNPD    WI P+         
Sbjct: 251 EDWDEEMDG--------EWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPD 302

Query: 312 PLLVAYWE-KTFKIDLFRPQIGVV---------------------NVTDADSVWMEIPDD 349
           P + AY       +DL++ + G +                      VT A    M+   D
Sbjct: 303 PSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQD 362

Query: 350 DDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           ++    EE ED        K   E +D++DD+D + DEED +D ++D++E
Sbjct: 363 EEQRLKEEEED-----KKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407


>gi|51477718 TATA box binding protein-associated factor, RNA
           polymerase II, Q [Homo sapiens]
          Length = 462

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 15/40 (37%), Positives = 27/40 (67%)

Query: 360 DWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           D + ++ S   +  DDDED+DD+D  ++ED D+ +D ++E
Sbjct: 319 DMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEE 358



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 14/46 (30%), Positives = 31/46 (67%)

Query: 354 TAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           T+ E +   E     + N +DD+++DD+D++ DE++++D D +++E
Sbjct: 314 TSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEE 359



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 12/29 (41%), Positives = 23/29 (79%)

Query: 371 NTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           N +D+DEDD+D+D  ++ED D+  ++++E
Sbjct: 332 NDDDEDEDDEDEDEDEDEDEDEDKEEEEE 360



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 13/41 (31%), Positives = 26/41 (63%)

Query: 358 LEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDD 398
           L +   D  S   + ED+D++D+D+D  ++ED D  ++++D
Sbjct: 321 LREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEED 361



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 10/27 (37%), Positives = 21/27 (77%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           EDD+++D+D+D  ++ED ++ ++D  E
Sbjct: 338 EDDEDEDEDEDEDEDEDKEEEEEDCSE 364



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 10/27 (37%), Positives = 21/27 (77%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           +D+DED+D+D++ DE+  ++ +D  +E
Sbjct: 339 DDEDEDEDEDEDEDEDKEEEEEDCSEE 365


>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
          Length = 259

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 16/31 (51%), Positives = 23/31 (74%)

Query: 369 KINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           K+    D++DDDDD+  D+ED+DD D DD+E
Sbjct: 155 KVKLAADEDDDDDDEEDDDEDDDDDDFDDEE 185



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 13/31 (41%), Positives = 26/31 (83%)

Query: 369 KINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           K+  ++DD+DDD++D+ +++D+DD DD++ E
Sbjct: 157 KLAADEDDDDDDEEDDDEDDDDDDFDDEEAE 187



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 13/27 (48%), Positives = 23/27 (85%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           EDDD+DD++DD+ D++D+D  D++ +E
Sbjct: 162 EDDDDDDEEDDDEDDDDDDFDDEEAEE 188


>gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]
          Length = 265

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 16/31 (51%), Positives = 23/31 (74%)

Query: 369 KINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           K+    D++DDDDD+  D+ED+DD D DD+E
Sbjct: 155 KVKLAADEDDDDDDEEDDDEDDDDDDFDDEE 185



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 13/31 (41%), Positives = 26/31 (83%)

Query: 369 KINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           K+  ++DD+DDD++D+ +++D+DD DD++ E
Sbjct: 157 KLAADEDDDDDDEEDDDEDDDDDDFDDEEAE 187



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 13/27 (48%), Positives = 23/27 (85%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           EDDD+DD++DD+ D++D+D  D++ +E
Sbjct: 162 EDDDDDDEEDDDEDDDDDDFDDEEAEE 188


>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
          Length = 294

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 16/31 (51%), Positives = 23/31 (74%)

Query: 369 KINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           K+    D++DDDDD+  D+ED+DD D DD+E
Sbjct: 155 KVKLAADEDDDDDDEEDDDEDDDDDDFDDEE 185



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 13/31 (41%), Positives = 26/31 (83%)

Query: 369 KINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           K+  ++DD+DDD++D+ +++D+DD DD++ E
Sbjct: 157 KLAADEDDDDDDEEDDDEDDDDDDFDDEEAE 187



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 13/27 (48%), Positives = 23/27 (85%)

Query: 373 EDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           EDDD+DD++DD+ D++D+D  D++ +E
Sbjct: 162 EDDDDDDEEDDDEDDDDDDFDDEEAEE 188


>gi|91598939 secreted phosphoprotein 1 isoform c [Homo sapiens]
          Length = 287

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 6/69 (8%)

Query: 334 VNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTE----DDDEDDDDDDNSDEED 389
           + V  ADS   E  +  +  ++EE  D+ ++ L  K N      DD +D+DDDD+ D +D
Sbjct: 17  IPVKQADSGSSE--EKQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQD 74

Query: 390 NDDSDDDDD 398
           + DS+D DD
Sbjct: 75  SIDSNDSDD 83



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 7/52 (13%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDD 396
           ++ D+DD       +D ++   S   N  DD +D DD   SDE  + D  D+
Sbjct: 60  DMDDEDD-------DDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 104



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 15/55 (27%), Positives = 28/55 (50%), Gaps = 11/55 (20%)

Query: 344 MEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDD 398
           M+  DDDD   +++            I++ D D+ DD DD+   +++  SD+ D+
Sbjct: 61  MDDEDDDDHVDSQD-----------SIDSNDSDDVDDTDDSHQSDESHHSDESDE 104


>gi|91206462 secreted phosphoprotein 1 isoform a [Homo sapiens]
          Length = 314

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 4/49 (8%)

Query: 354 TAEELEDWIEDVLSGKINTE----DDDEDDDDDDNSDEEDNDDSDDDDD 398
           ++EE  D+ ++ L  K N      DD +D+DDDD+ D +D+ DS+D DD
Sbjct: 62  SSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD 110



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 20/100 (20%)

Query: 299 PDLSILWIDPDDFPLLVAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEEL 358
           PD    W++PD           + K +L  PQ  V +    D     +P   +     E 
Sbjct: 37  PDAVATWLNPDP----------SQKQNLLAPQNAVSSEETNDFKQETLPSKSN-----ES 81

Query: 359 EDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDD 398
            D ++D+     + EDDD+  D  D+ D  D+DD DD DD
Sbjct: 82  HDHMDDM-----DDEDDDDHVDSQDSIDSNDSDDVDDTDD 116


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 1/70 (1%)

Query: 330  QIGVVNVTDADSVWMEIPDDDDLPTAEELEDWI-EDVLSGKINTEDDDEDDDDDDNSDEE 388
            Q   +     DS+ +  P+D++  T EE      ED    +   E+++ED++DD   DE 
Sbjct: 2392 QASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEG 2451

Query: 389  DNDDSDDDDD 398
            +  D DDDDD
Sbjct: 2452 EEGDEDDDDD 2461



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 15/65 (23%), Positives = 37/65 (56%)

Query: 335  NVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSD 394
            N++ A ++     D  ++   E+ E+  ++  S   N ++DD  D++++  ++E++D  D
Sbjct: 2389 NLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQED 2448

Query: 395  DDDDE 399
            D+ +E
Sbjct: 2449 DEGEE 2453



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 16/66 (24%), Positives = 37/66 (56%)

Query: 334  VNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDS 393
            +N+ D +       ++D   + E+ +D  ++    + + EDD EDD+ ++  +++D+D S
Sbjct: 2404 MNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGS 2463

Query: 394  DDDDDE 399
            + + DE
Sbjct: 2464 EMELDE 2469



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 19/47 (40%), Positives = 24/47 (51%)

Query: 348  DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSD 394
            D+DD    EE E+  E+        E+ DEDDDDD +  E D D  D
Sbjct: 2427 DEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPD 2473



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%)

Query: 324  IDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDD 383
            +++  P+    +  + DS      +DD     EE E+  ED        E D+  DDDDD
Sbjct: 2404 MNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDE--DDDDD 2461

Query: 384  NSDEEDNDDSDD 395
             S+ E ++D  D
Sbjct: 2462 GSEMELDEDYPD 2473


>gi|19924161 RPB5-mediating protein isoform b [Homo sapiens]
          Length = 495

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 5/57 (8%)

Query: 347 PDDDDLPTAEELEDWIEDVLSGKINTE-----DDDEDDDDDDNSDEEDNDDSDDDDD 398
           P   D+ ++E     +   L+  +N       DDD+DDDDDD+ D  D+DD D+D +
Sbjct: 227 PCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHE 283



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 16/47 (34%), Positives = 28/47 (59%)

Query: 353 PTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           P + ++   +   ++G  +   DD+DDDDDD+ D+  +DD  D+D E
Sbjct: 237 PFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHE 283


>gi|19924159 RPB5-mediating protein isoform a [Homo sapiens]
          Length = 535

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 5/57 (8%)

Query: 347 PDDDDLPTAEELEDWIEDVLSGKINTE-----DDDEDDDDDDNSDEEDNDDSDDDDD 398
           P   D+ ++E     +   L+  +N       DDD+DDDDDD+ D  D+DD D+D +
Sbjct: 267 PCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHE 323



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 16/47 (34%), Positives = 28/47 (59%)

Query: 353 PTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           P + ++   +   ++G  +   DD+DDDDDD+ D+  +DD  D+D E
Sbjct: 277 PFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHE 323


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 20/82 (24%)

Query: 338 DADSVWMEIPDDDDLPTAEELEDWIEDVLS--GKINT------------------EDDDE 377
           D DS   E  D++      E EDW + V+   G                      ED D 
Sbjct: 453 DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDS 512

Query: 378 DDDDDDNSDEEDNDDSDDDDDE 399
           D +++D+ +E+D D+ DDDD+E
Sbjct: 513 DSEEEDDEEEDDEDEDDDDDEE 534


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 26/64 (40%), Positives = 34/64 (53%), Gaps = 4/64 (6%)

Query: 338 DADSVWMEIPDD--DDLPTAEELEDWIE--DVLSGKINTEDDDEDDDDDDNSDEEDNDDS 393
           D +S   E PDD  DD    ++  D  E  D  S   +  DD+ DD  DDNSD+  +D+S
Sbjct: 150 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNS 209

Query: 394 DDDD 397
           DD D
Sbjct: 210 DDSD 213



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 338 DADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDD--DDNSDEEDNDDSDD 395
           D +S   ++PDD+   ++++  D   D  S   +  DD  DD D  DD+SD+ D  D   
Sbjct: 180 DDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSS 239

Query: 396 DDDE 399
           DD E
Sbjct: 240 DDSE 243



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 19/57 (33%), Positives = 36/57 (63%), Gaps = 3/57 (5%)

Query: 344 MEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSD--EEDNDDSDDDDD 398
           +E+PDD+    +E  +D  +D  +   N++D +  DD+ D+S+  ++++DDSD  DD
Sbjct: 136 LEVPDDNS-DDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDD 191



 Score = 35.8 bits (81), Expect = 0.070
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDD---DDDNSDEEDNDDSDDDDD 398
           DD D+P  +  +  + D  S   +  DD  DD    DD + D E  DDS DD +
Sbjct: 210 DDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 263



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 7/71 (9%)

Query: 335 NVTDADSVWMEIPDD--DDLPTAEELEDWIE--DVLSGKINTEDDDEDDD---DDDNSDE 387
           +V D  S   E PDD  DD    ++  D  E  D  S      DD  DD    DD + D 
Sbjct: 233 DVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDS 292

Query: 388 EDNDDSDDDDD 398
           E +DDS DD +
Sbjct: 293 EASDDSSDDSE 303



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 5/65 (7%)

Query: 338 DADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDD---DDNSDEED-NDDS 393
           D +S   E PDD+    +E  +D  +D      N++D  +D+ D   DDNSD+ D  DD 
Sbjct: 160 DDNSDDSEAPDDNS-DDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDK 218

Query: 394 DDDDD 398
            DD D
Sbjct: 219 SDDSD 223



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 3/56 (5%)

Query: 345 EIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSD--EEDNDDSDDDDD 398
           E PDD     +E  +D  +D  +   +++D +  DD  D+SD  E+ +DDSD  DD
Sbjct: 273 EAPDDSS-DDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDD 327



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)

Query: 335 NVTDADSVWMEIPDD--DDLPTAEELEDWIE--DVLSGKINTEDDDEDDDDDDNSDEEDN 390
           +V D  S   ++PDD  DD    ++  D  E  D  S      DD  DD +  +   +D+
Sbjct: 223 DVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDS 282

Query: 391 DDSDDDDDE 399
           + SDD  D+
Sbjct: 283 EASDDSSDD 291



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 23/61 (37%), Positives = 26/61 (42%), Gaps = 7/61 (11%)

Query: 345 EIPDD--DDLPTAEELEDWIE--DVLSGKINTEDDDEDD---DDDDNSDEEDNDDSDDDD 397
           E PDD  DD    ++  D  E  D  S      DD  DD    DD + D E  DD  DD 
Sbjct: 253 EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDS 312

Query: 398 D 398
           D
Sbjct: 313 D 313



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 18/71 (25%)

Query: 344 MEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDD-------DDNSDE-----EDND 391
           +EI  DD+ P    ++  I++     I   DDD DDD+       DDNSD+     +++D
Sbjct: 98  LEINSDDESPECCHVKPAIQEP---PIVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSD 154

Query: 392 DS---DDDDDE 399
           DS   DD+ D+
Sbjct: 155 DSEAPDDNSDD 165



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 6/54 (11%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDD--DDNSDEED--NDDSDDDD 397
           DD+D     +LE  + D  S      DD+ DD +  DDNSD+ +  +D+SDD +
Sbjct: 126 DDNDDDNGNDLE--VPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSE 177



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 14/52 (26%), Positives = 23/52 (44%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399
           DD D+P     +  + D  S      DD  DD +  +   +D++  DD  D+
Sbjct: 220 DDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD 271



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 16/63 (25%), Positives = 26/63 (41%)

Query: 337 TDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDD 396
           +D   V  +  DD D+P     +    D  S      DD  DD +  +   +D++  DD 
Sbjct: 219 SDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDS 278

Query: 397 DDE 399
            D+
Sbjct: 279 SDD 281



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 5/57 (8%)

Query: 348 DDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSD--EEDNDDS---DDDDDE 399
           DDD+    E  +D  +D  +   N++D +  DD+ D+S+  ++++DDS   DD+ D+
Sbjct: 129 DDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD 185


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.139    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,362,765
Number of Sequences: 37866
Number of extensions: 737642
Number of successful extensions: 13147
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 269
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 6624
Number of HSP's gapped (non-prelim): 3052
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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