Guide to the Human Genome
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Name: P4HB Sequence: fasta or formatted (508aa) NCBI GI: 20070125
Description:

prolyl 4-hydroxylase, beta subunit precursor

Referenced in:

Collagen
Glutathione Pathways
Lipoproteins
Additional Protein Modifications
Thyroid and Thyroid Hormone Receptor

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.6         49           3
 C cysteine            1.4          7           1
 D aspartate           8.5         43           4
 E glutamate          11.0         56           3
 F phenylalanine       6.5         33           2
 G glycine             5.7         29           2
 H histidine           2.2         11           1
 I isoleucine          4.5         23           1
 K lysine              9.3         47           2
 L leucine             9.1         46           2
 M methionine          1.0          5           1
 N asparagine          3.0         15           2
 P proline             4.1         21           1
 Q glutamine           2.6         13           2
 R arginine            3.1         16           2
 S serine              4.5         23           2
 T threonine           4.5         23           2
 V valine              6.1         31           2
 W tryptophan          1.0          5           1
 Y tyrosine            2.4         12           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   prolyl 4-hydroxylase, beta subunit precursor 
PDIA2                 0.444   protein disulfide isomerase A2 
PDILT                 0.254   protein disulfide isomerase-like, testis expressed [...
PDIA4                 0.235   protein disulfide isomerase A4 
PDIA3                 0.228   protein disulfide-isomerase A3 precursor 
ERP27                 0.102   endoplasmic reticulum protein 27 kDa 
PDIA6                 0.073   protein disulfide isomerase A6 
TMX3                  0.069   thioredoxin domain containing 10 
ERP44                 0.062   thioredoxin domain containing 4 (endoplasmic reticul...
TXNDC5                0.061   thioredoxin domain containing 5 isoform 1 precursor ...
TXNDC5                0.061   thioredoxin domain containing 5 isoform 3 
PDIA5                 0.052   protein disulfide isomerase A5 
QSOX2                 0.039   quiescin Q6 sulfhydryl oxidase 2 
TXN2                  0.036   thioredoxin 2 precursor 
DNAJC10               0.035   DnaJ (Hsp40) homolog, subfamily C, member 10 
TMX1                  0.035   thioredoxin domain containing 1 
QSOX1                 0.033   quiescin Q6 sulfhydryl oxidase 1 isoform b 
QSOX1                 0.033   quiescin Q6 sulfhydryl oxidase 1 isoform a 
CASQ2                 0.027   cardiac calsequestrin 2 precursor 
TXN                   0.024   thioredoxin 
TXNDC16               0.022   thioredoxin domain containing 16 isoform 2 
TXNDC16               0.022   thioredoxin domain containing 16 isoform 1 
CASQ1                 0.020   calsequestrin 1 
TXNDC11               0.020   thioredoxin domain containing 11 
TXNDC2                0.019   thioredoxin domain-containing 2 isoform 1 
TXNDC2                0.019   thioredoxin domain-containing 2 isoform 2 
TXNDC2                0.019   thioredoxin domain-containing 2 isoform 1 
TMX4                  0.017   thioredoxin-related transmembrane protein 4 
GLRX3                 0.015   glutaredoxin 3 
TMX2                  0.015   thioredoxin domain containing 14 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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