BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239754940 PREDICTED: hypothetical protein [Homo sapiens] (159 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239754940 PREDICTED: hypothetical protein [Homo sapiens] 332 6e-92 gi|239749482 PREDICTED: hypothetical protein [Homo sapiens] 272 8e-74 gi|239743620 PREDICTED: hypothetical protein [Homo sapiens] 272 8e-74 gi|163965366 nascent polypeptide-associated complex alpha subuni... 65 3e-11 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 64 4e-11 gi|160707881 formin 2 [Homo sapiens] 60 1e-09 gi|33356148 formin-like 1 [Homo sapiens] 59 1e-09 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 59 2e-09 gi|153792074 proline rich 12 [Homo sapiens] 59 2e-09 gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 58 3e-09 gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 58 3e-09 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 57 7e-09 gi|56549694 enabled homolog isoform a [Homo sapiens] 57 9e-09 gi|39930375 enabled homolog isoform b [Homo sapiens] 57 9e-09 gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 56 1e-08 gi|7706501 WW domain binding protein 11 [Homo sapiens] 56 1e-08 gi|122937321 UNC homeobox [Homo sapiens] 55 2e-08 gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] 55 2e-08 gi|22027541 programmed cell death 7 [Homo sapiens] 55 2e-08 gi|47132519 Ras association and pleckstrin homology domains 1 is... 55 3e-08 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 55 3e-08 gi|157168329 formin 1 [Homo sapiens] 55 3e-08 gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 55 3e-08 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 4e-08 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 54 4e-08 gi|110832843 TBP-associated factor 4 [Homo sapiens] 54 4e-08 gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] 54 6e-08 gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 7e-08 gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 7e-08 gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 7e-08 >gi|239754940 PREDICTED: hypothetical protein [Homo sapiens] Length = 159 Score = 332 bits (852), Expect = 6e-92 Identities = 159/159 (100%), Positives = 159/159 (100%) Query: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP Sbjct: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 Query: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR Sbjct: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 Query: 121 PSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 PSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP Sbjct: 121 PSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 >gi|239749482 PREDICTED: hypothetical protein [Homo sapiens] Length = 195 Score = 272 bits (696), Expect = 8e-74 Identities = 138/162 (85%), Positives = 140/162 (86%), Gaps = 4/162 (2%) Query: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP Sbjct: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 Query: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR Sbjct: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 Query: 121 PSSPPPSPPSPPVP----TAQSSLPAPWPPQGPRSPAPSLRA 158 PSSPPP P P P S+L AP PP P S+ A Sbjct: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTA 162 Score = 30.4 bits (67), Expect = 0.67 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 22/113 (19%) Query: 6 QAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGI----RPAPAAAHPPAPR 61 Q R +GGG G + P LP PAL G + P P A P +P Sbjct: 76 QPRRRSPGPQGGGGG-----DIASP----LP-PALQPRGAPAVPAAPSPGPLPARPSSPP 125 Query: 62 ERPAAAR--------LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP 106 RP+ SALAA +P P PQG P + + GAP Sbjct: 126 PRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAP 178 >gi|239743620 PREDICTED: hypothetical protein [Homo sapiens] Length = 285 Score = 272 bits (696), Expect = 8e-74 Identities = 138/162 (85%), Positives = 140/162 (86%), Gaps = 4/162 (2%) Query: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP Sbjct: 1 MPGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP 60 Query: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR Sbjct: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPAR 120 Query: 121 PSSPPPSPPSPPVP----TAQSSLPAPWPPQGPRSPAPSLRA 158 PSSPPP P P P S+L AP PP P S+ A Sbjct: 121 PSSPPPRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTA 162 Score = 30.4 bits (67), Expect = 0.67 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 22/113 (19%) Query: 6 QAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGI----RPAPAAAHPPAPR 61 Q R +GGG G + P LP PAL G + P P A P +P Sbjct: 76 QPRRRSPGPQGGGGG-----DIASP----LP-PALQPRGAPAVPAAPSPGPLPARPSSPP 125 Query: 62 ERPAAAR--------LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP 106 RP+ SALAA +P P PQG P + + GAP Sbjct: 126 PRPSLPSGPHRPVLPPSALAAPRPPLARPLPQGSVTAREQEQRPRSRRRAGAP 178 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 64.7 bits (156), Expect = 3e-11 Identities = 41/110 (37%), Positives = 48/110 (43%), Gaps = 7/110 (6%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG--GDIASPLPPALQPRGAPA 107 P P AA PP+P+ PA A P P P+GG +P PPA P Sbjct: 940 PTPPAATPPSPKGGPATPS-PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998 Query: 108 VPAAPSPGPLPARPSSPPP----SPPSPPVPTAQSSLPAPWPPQGPRSPA 153 PA PSP P P+ PP SP + P P S+ PA PP SPA Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048 Score = 62.8 bits (151), Expect = 1e-10 Identities = 44/120 (36%), Positives = 52/120 (43%), Gaps = 18/120 (15%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P P A PP+P+ PAA A+ P P P+G A+PLP +GAP P Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA---ATPLP-----KGAPTTP 1060 Query: 110 AAPSPGP--------LPARPSSPPPSPPSPP-VPTAQSSLPAPWPPQG-PRSPAPSLRAP 159 AA P P L P+ P +PPSP P S AP PP P SP L P Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120 Score = 58.5 bits (140), Expect = 2e-09 Identities = 47/145 (32%), Positives = 65/145 (44%), Gaps = 34/145 (23%) Query: 30 PGGFCLPG---PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQG 86 P G LP P V L + PA PAP++ PA + S+ + + R +P P+G Sbjct: 875 PKGVTLPPKETPTPSVVNLPFPKEGPAT---PAPKQAPALSMTSS--SPKKARATPAPKG 929 Query: 87 GGGGDIASPLPPALQPRGAPAVPAA-----------PSPGPLPARPSSPPPSP---PSPP 132 +P + P+GAP PAA PSP P P++ PPSP P+ P Sbjct: 930 ---------IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980 Query: 133 VPTAQSSLPAPWPPQ---GPRSPAP 154 P + PA PP GP +P+P Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSP 1005 Score = 58.5 bits (140), Expect = 2e-09 Identities = 44/136 (32%), Positives = 52/136 (38%), Gaps = 32/136 (23%) Query: 52 PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDI--ASPLPPALQPRGAPAVP 109 P AA PP+P+ PAA L A P P P+GG +P PPA P P Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094 Query: 110 AAPSPGPLPARPSSPPP--------------------SPPSP------PVPTAQSSLPAP 143 A PSP P P++ PP +PPSP P P + PA Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154 Query: 144 WPPQGPRSPAPSLRAP 159 PP SP L P Sbjct: 1155 TPP----SPKGGLATP 1166 Score = 58.2 bits (139), Expect = 3e-09 Identities = 39/127 (30%), Positives = 53/127 (41%), Gaps = 18/127 (14%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG-------GGGDIASPLPPALQ- 101 P P AA PP+P+ PA A P P P+GG G + PP+ + Sbjct: 1080 PTPPAATPPSPKGGPATPSPKG-APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138 Query: 102 ------PRGAPAVPAAPSPGPLPARPSSPPPSPPSPPV---PTAQSSLPAPWPPQGPRSP 152 P+GAP PAA P P + PP P+ P P+ + L P P P +P Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198 Query: 153 APSLRAP 159 A + +P Sbjct: 1199 AATPPSP 1205 Score = 57.4 bits (137), Expect = 5e-09 Identities = 37/101 (36%), Positives = 45/101 (44%), Gaps = 6/101 (5%) Query: 58 PAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIA--SPLPPALQPRGAPAVPAAPSPG 115 PAP+ PA+ A P P P+GG +P PPA P PA PSP Sbjct: 925 PAPKGIPASPSPKG-APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK 983 Query: 116 PLPARPSSPPPSP---PSPPVPTAQSSLPAPWPPQGPRSPA 153 P P++ PPSP P+ P P + PA PP SPA Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024 Score = 52.8 bits (125), Expect = 1e-07 Identities = 42/126 (33%), Positives = 54/126 (42%), Gaps = 26/126 (20%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P AA PP+P+ A A P P P+GG +A+P P+GAP P Sbjct: 1172 PTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGG----LATP-----SPKGAPTTP 1221 Query: 110 AA-----------PSPGPLPARPSSPPPSP---PSPPVPTAQSSLPAPWPP--QGPRSPA 153 AA PSP P P++ PPSP P+ P P + PA PP +G + Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281 Query: 154 PSLRAP 159 P AP Sbjct: 1282 PHKGAP 1287 Score = 52.4 bits (124), Expect = 2e-07 Identities = 40/126 (31%), Positives = 52/126 (41%), Gaps = 22/126 (17%) Query: 31 GGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGG 90 GG P P P AA PP+P+ A A P P P+GG Sbjct: 1184 GGLATPSPKGA--------PTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGG--- 1231 Query: 91 DIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPV---PTAQSSLPAPWPPQ 147 +A+P P+GAP PAA P P + PP P+PP P+ + L P P + Sbjct: 1232 -LATP-----SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP-PHK 1284 Query: 148 GPRSPA 153 G +PA Sbjct: 1285 GAPNPA 1290 Score = 52.0 bits (123), Expect = 2e-07 Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 27/122 (22%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P PA PP+P+ PA + A P P P+G G PP P+GAP P Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKG-APTPPAATPPSPKGSPG------TPP---PKGAPTPP 1336 Query: 110 AA--PSPGPLPARPSSPPPSPPSPPVPTAQS---------------SLPAPWPPQGPRSP 152 A PSP P P++ P S P P+++ ++ P P +GP P Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396 Query: 153 AP 154 +P Sbjct: 1397 SP 1398 Score = 51.6 bits (122), Expect = 3e-07 Identities = 44/137 (32%), Positives = 57/137 (41%), Gaps = 34/137 (24%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG-------GGGDIASPLPPALQ- 101 P P AA PP+P+ A A P P P+GG G + PP+ + Sbjct: 1103 PMPPAATPPSPKGGLATPPHKG-APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161 Query: 102 ------PRGAPAVPAA-----------PSPGPLPARPSSPPPSP------PSPP-VPTAQ 137 P+GAP PAA PSP P P++ PPSP PSP PT Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221 Query: 138 SSLPAPWPPQGPRSPAP 154 ++ P P P G +P+P Sbjct: 1222 AATP-PSPKGGLATPSP 1237 Score = 51.6 bits (122), Expect = 3e-07 Identities = 46/142 (32%), Positives = 57/142 (40%), Gaps = 26/142 (18%) Query: 31 GGFCLPGPALVVAGLDGIRPAPA---AAHPPAPRERPAAARLSALA---AAQPRRRSPGP 84 GG P P P+P A PP P AA +L A P + +P P Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNP 1289 Query: 85 Q-----GGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPP----PSPP--SPPV 133 GG SP P+GAP PAA P P P +PP P+PP +PP Sbjct: 1290 AVVTPPSPKGGPATSP------PKGAPTPPAATPPSP-KGSPGTPPPKGAPTPPAVTPPS 1342 Query: 134 PTAQSSLPAPWPPQ--GPRSPA 153 P +LPA P GP +P+ Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPS 1364 Score = 49.3 bits (116), Expect = 1e-06 Identities = 40/143 (27%), Positives = 49/143 (34%), Gaps = 23/143 (16%) Query: 31 GGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGG 90 GG P P P AA PP+P+ A A P P P+GG Sbjct: 1207 GGLATPSPKGA--------PTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGPAT 1257 Query: 91 DI--ASPLPPALQP------------RGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTA 136 +P PPA P +GAP P P +SPP P+PP T Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317 Query: 137 QSSLPAPWPPQGPRSPAPSLRAP 159 S +P P +P P P Sbjct: 1318 PSPKGSPGTPPPKGAPTPPAVTP 1340 Score = 46.6 bits (109), Expect = 9e-06 Identities = 31/118 (26%), Positives = 51/118 (43%), Gaps = 21/118 (17%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P A PP+P+E PA +++ ++ + +P P G +P PA+ P VP Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG-------APTLPAVIPSSPKEVP 1517 Query: 110 AAPSPGPLPARPSSPPPS--------------PPSPPVPTAQSSLPAPWPPQGPRSPA 153 A PS P P++ S PP+ VP+ + + P P + P +P+ Sbjct: 1518 ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS 1575 Score = 45.1 bits (105), Expect = 3e-05 Identities = 35/112 (31%), Positives = 43/112 (38%), Gaps = 14/112 (12%) Query: 52 PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAA 111 PA P PA LS A G GD+ PPA+ P PA Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT---PPAVTPVSLKKAPAT 1449 Query: 112 PSPGPLPARPSS---------PPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 +P PA PSS PPSP PP P ++ + P + P +PAP Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS--PKKAPATPAP 1499 Score = 44.7 bits (104), Expect = 3e-05 Identities = 40/133 (30%), Positives = 53/133 (39%), Gaps = 27/133 (20%) Query: 47 GIRPAPAAAH---PPAPRERP---AAARLSALAAAQPRRRSPGPQGGGGGDIASPLP--- 97 G + +PA H PP+P+ P A LS P + +P P + P P Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV-----VNLPFPKEG 899 Query: 98 PALQ-PRGAPAVP----------AAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPP 146 PA P+ APA+ A P+P +PA PS P P+PP T S P P Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS--PKGAPTPPAATPPSPKGGPATP 957 Query: 147 QGPRSPAPSLRAP 159 +P P P Sbjct: 958 SPKWAPTPPAATP 970 Score = 41.2 bits (95), Expect = 4e-04 Identities = 40/128 (31%), Positives = 49/128 (38%), Gaps = 27/128 (21%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG-----------GGGDIAS---- 94 P P AA PP+P+ P A P P P+G GG S Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKG-APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368 Query: 95 PLPPALQP--RGAPAV--------PAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPW 144 P PPA P +G PA+ PA PSP P P+ P SP P T + A Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA-TPVTREGAAT 1427 Query: 145 PPQGPRSP 152 P +G +P Sbjct: 1428 PSKGDLTP 1435 Score = 38.9 bits (89), Expect = 0.002 Identities = 40/143 (27%), Positives = 50/143 (34%), Gaps = 17/143 (11%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 P +P P A + + APA PA + A P+ P Sbjct: 1550 PPAMTVPSPKKTPA-IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPGPL----PARPSSPPPSPPSP---------PVPTA 136 +P PPA+ P PA P+P P PSS SP SP VP A Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA 1668 Query: 137 QSSLPAPWPPQGPRSPAPSLRAP 159 LPA +GP + L AP Sbjct: 1669 SKGLPA---KKGPTALKEVLVAP 1688 Score = 34.7 bits (78), Expect = 0.035 Identities = 27/96 (28%), Positives = 36/96 (37%), Gaps = 3/96 (3%) Query: 53 AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112 A+ P P P + + L AA + P P+ A+P PP P VP P Sbjct: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS--AAPSPPVSLPLAPSPVPTLP 1811 Query: 113 SPGP-LPARPSSPPPSPPSPPVPTAQSSLPAPWPPQ 147 LP+ P SP P P + L PP+ Sbjct: 1812 PKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPE 1847 Score = 33.1 bits (74), Expect = 0.10 Identities = 26/110 (23%), Positives = 38/110 (34%), Gaps = 2/110 (1%) Query: 48 IRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP--RGA 105 + PAP + R + A + P P + G G +++ P L P + + Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745 Query: 106 PAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPS 155 P P +PP S S P+ A P P S APS Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS 1795 Score = 32.0 bits (71), Expect = 0.23 Identities = 21/54 (38%), Positives = 22/54 (40%) Query: 102 PRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPS 155 P P V AAP P SS P P SP A+ SL P P P S S Sbjct: 557 PTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610 Score = 32.0 bits (71), Expect = 0.23 Identities = 33/114 (28%), Positives = 40/114 (35%), Gaps = 6/114 (5%) Query: 52 PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP-- 109 P P A A A P ++ G SP P P + P Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774 Query: 110 AAPSPGPLPARPSSPPPSPPSPPV--PTAQSSLPAPWPPQG--PRSPAPSLRAP 159 AA LP S+ + PSPPV P A S +P P Q P SP L +P Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESP 1828 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 64.3 bits (155), Expect = 4e-11 Identities = 49/139 (35%), Positives = 54/139 (38%), Gaps = 11/139 (7%) Query: 24 RVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP------RERPAAARLSALAAAQP 77 R G P P A A P PA PPAP P AA +A A P Sbjct: 103 RRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP 162 Query: 78 RRRSPGPQGGGGGDIASPLP-PALQPRGAPAVPAAPSPGPLPARPSSPPPSPPS--PPVP 134 PGP+ +A+P P PA P AP PA P P PA + PP PP PP P Sbjct: 163 GPAQPGPRAQRAAPLAAPPPAPAAPPAVAP--PAGPRRAPPPAVAAREPPLPPPPQPPAP 220 Query: 135 TAQSSLPAPWPPQGPRSPA 153 Q P P P P A Sbjct: 221 PQQQQPPPPQPQPPPEGGA 239 Score = 60.8 bits (146), Expect = 5e-10 Identities = 40/112 (35%), Positives = 54/112 (48%), Gaps = 5/112 (4%) Query: 48 IRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107 ++P A PPAP P A +A AAA P +P P +A+ P A A Sbjct: 99 VQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPP---PAPVAAAAPARAPRAAAAA 155 Query: 108 VPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGP-RSPAPSLRA 158 A PSPGP P + +P + P P A ++ PA PP GP R+P P++ A Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAP-PPAPAAPPAVAPPAGPRRAPPPAVAA 206 Score = 51.2 bits (121), Expect = 4e-07 Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 34/109 (31%) Query: 73 AAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSP-------- 124 A QP RR P P PP PRGAPA AA +P P PA P P Sbjct: 97 ARVQPPRRGATP----------PAPPRA-PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAP 145 Query: 125 -------------PPSP-PSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 PPSP P+ P P AQ + P PP P +P P++ P Sbjct: 146 ARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAP-PAVAPP 193 Score = 43.5 bits (101), Expect = 8e-05 Identities = 43/156 (27%), Positives = 58/156 (37%), Gaps = 34/156 (21%) Query: 35 LPGPALVVAGLDGIRPAPAAAHP----------PAPRERPAAARLSALAAAQPRRRSPGP 84 LP P A + +AA P + R R A L + RR P P Sbjct: 7 LPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEP 66 Query: 85 QGGGG-----------------GDIASPLPPALQP--RGA--PAVPAAPSPGPLPARPSS 123 + G I+ +QP RGA PA P AP P A ++ Sbjct: 67 ERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAA 126 Query: 124 PPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 PPP+P PP P + + A P + PR+ A + AP Sbjct: 127 PPPTPAPPPPP---APVAAAAPARAPRAAAAAATAP 159 Score = 27.7 bits (60), Expect = 4.3 Identities = 30/75 (40%), Positives = 32/75 (42%), Gaps = 9/75 (12%) Query: 11 GAAVRGGGAGRRV--RVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAAR 68 G AVR GGA R V R V GG G L + G+ AAA R R R Sbjct: 237 GGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAA-----RGRLERTR 291 Query: 69 LSALAAAQPRRRSPG 83 L ALA PR PG Sbjct: 292 LGALAL--PRGDRPG 304 Score = 26.6 bits (57), Expect = 9.6 Identities = 30/112 (26%), Positives = 35/112 (31%), Gaps = 16/112 (14%) Query: 49 RPAPAAAH-------PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQ 101 RPA A H P + +ER Q R P P G G + S A+ Sbjct: 355 RPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAP-GSGTRQVFSMA--AMN 411 Query: 102 PRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPA 153 G A A P SP P PP P P PP P+ Sbjct: 412 KEGGTASVATGPDSP------SPVPLPPGKPALPGADGTPFGCPPGRKEKPS 457 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 59.7 bits (143), Expect = 1e-09 Identities = 49/136 (36%), Positives = 51/136 (37%), Gaps = 16/136 (11%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG LP P L AG+ P P AA PP P P L P P P G Sbjct: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPP---PLPGAGIPLPPPLPGAGIPPPPPLPG 983 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPG-----PLPARPSSPPPS------PPSPPVPTAQS 138 I P PP L G P P P G PLP PPP PP PP+P A Sbjct: 984 AGI--PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041 Query: 139 SLPAPWPPQGPRSPAP 154 P P P G P P Sbjct: 1042 PPPPPLPGAGIPPPPP 1057 Score = 57.8 bits (138), Expect = 4e-09 Identities = 49/136 (36%), Positives = 52/136 (38%), Gaps = 27/136 (19%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ + P P A PP P P AA P P P G G Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPP---PLPG-----AAIPP----PPPLPGAG 963 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPG-----PLPARPSSPPPS------PPSPPVPTAQS 138 PLPP L G P P P G PLP PPP PP PP+P A Sbjct: 964 ----IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019 Query: 139 SLPAPWPPQGPRSPAP 154 P P P G P P Sbjct: 1020 PPPPPLPGAGIPPPPP 1035 Score = 54.7 bits (130), Expect = 3e-08 Identities = 49/140 (35%), Positives = 53/140 (37%), Gaps = 12/140 (8%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P A P P G G Sbjct: 971 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAG 1029 Query: 90 GDIASPLPPALQPRGAPAVPAA--PSPGPLPARPSSPPPS------PPSPPVPTAQSSLP 141 PLP A P P +P A P P PLP PPP PP PP+P A P Sbjct: 1030 IPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1088 Query: 142 APWPPQG--PRSPAPSLRAP 159 P P G P P P + P Sbjct: 1089 PPLPGAGIPPPPPLPGVGIP 1108 Score = 53.9 bits (128), Expect = 6e-08 Identities = 47/133 (35%), Positives = 50/133 (37%), Gaps = 10/133 (7%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P A P P G G Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAG 1062 Query: 90 GDIASPLPPALQPRGAPAVPAA--PSPGPLPARPSSPPPS------PPSPPVPTAQSSLP 141 PLP A P P +P A P P PLP PPP PP PP+P A P Sbjct: 1063 IPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPP 1121 Query: 142 APWPPQGPRSPAP 154 P P G P P Sbjct: 1122 PPLPGAGIPPPPP 1134 Score = 53.5 bits (127), Expect = 7e-08 Identities = 47/133 (35%), Positives = 50/133 (37%), Gaps = 10/133 (7%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P A P P G G Sbjct: 982 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040 Query: 90 GDIASPLPPALQPRGAPAVPAA--PSPGPLPARPSSPPPS------PPSPPVPTAQSSLP 141 PLP A P P +P A P P PLP PPP PP PP+P A P Sbjct: 1041 IPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1099 Query: 142 APWPPQGPRSPAP 154 P P G P P Sbjct: 1100 PPLPGVGIPPPPP 1112 Score = 53.5 bits (127), Expect = 7e-08 Identities = 49/140 (35%), Positives = 53/140 (37%), Gaps = 12/140 (8%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P A P P G G Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAG 1073 Query: 90 GDIASPLPPALQPRGAPAVPAA--PSPGPLPARPSSPPPS------PPSPPVPTAQSSLP 141 PLP A P P +P A P P PLP PPP PP PP+P A P Sbjct: 1074 IPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1132 Query: 142 APWPPQG--PRSPAPSLRAP 159 P P G P P P + P Sbjct: 1133 PPLPGAGIPPPPPLPRVGIP 1152 Score = 53.5 bits (127), Expect = 7e-08 Identities = 47/143 (32%), Positives = 51/143 (35%), Gaps = 18/143 (12%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P P P P G Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1104 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPG-----PLPARPSSPPPS------PPSPPVPTAQS 138 + P PP L G P P P G PLP PPP PP PP+P A Sbjct: 1105 --VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGI 1162 Query: 139 SLPAPWPPQG--PRSPAPSLRAP 159 P P P G P P P + P Sbjct: 1163 PPPPPLPGAGIPPPPPLPGVGIP 1185 Score = 52.8 bits (125), Expect = 1e-07 Identities = 49/140 (35%), Positives = 53/140 (37%), Gaps = 12/140 (8%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P A PP P P A P P G G Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117 Query: 90 GDIASPLPPALQPRGAPAVPAA--PSPGPLPARPSSPPPS------PPSPPVPTAQSSLP 141 PLP A P P +P A P P PLP PPP PP PP+P A P Sbjct: 1118 IPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1176 Query: 142 APWPPQG--PRSPAPSLRAP 159 P P G P P P + P Sbjct: 1177 PPLPGVGIPPPPPLPGVGIP 1196 Score = 50.8 bits (120), Expect = 5e-07 Identities = 46/143 (32%), Positives = 49/143 (34%), Gaps = 18/143 (12%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P PP P P P P P G Sbjct: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPG 1137 Query: 90 GDIASPLPPALQPRGAPAVPAAPSPG-----PLPARPSSPPPS------PPSPPVPTAQS 138 I P PP L G P P P G PLP PPP PP PP+P Sbjct: 1138 AGI--PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGI 1195 Query: 139 SLPAPWPPQG--PRSPAPSLRAP 159 P P P G P P P + P Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIP 1218 Score = 50.1 bits (118), Expect = 8e-07 Identities = 37/109 (33%), Positives = 41/109 (37%), Gaps = 16/109 (14%) Query: 57 PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPG- 115 PP P P P P P G ++ P PP L G P P P G Sbjct: 877 PPPPPPLPGMT-----VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931 Query: 116 -PLPARPSS--PPPS-------PPSPPVPTAQSSLPAPWPPQGPRSPAP 154 PLP P + PPP PP PP+P A LP P P G P P Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980 Score = 47.4 bits (111), Expect = 5e-06 Identities = 43/138 (31%), Positives = 49/138 (35%), Gaps = 24/138 (17%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L G+ P P A PP P P A P PG Sbjct: 1136 PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP---PLPG-----AGIPPPPPLPG------ 1181 Query: 90 GDIASPLPPALQPRGAPAVP-----AAPSPGPLPARPSSPPPSPPSPPVPTA---QSSLP 141 + P PP L G P P P P PLP P P+PP PP T LP Sbjct: 1182 --VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLP 1239 Query: 142 APWPPQGPRSPAPSLRAP 159 PP P+ + +L P Sbjct: 1240 VSGPPLLPQVGSSTLPTP 1257 Score = 39.7 bits (91), Expect = 0.001 Identities = 36/106 (33%), Positives = 38/106 (35%), Gaps = 18/106 (16%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P P A PP P P A L P P G G P PP L P P Sbjct: 914 PLPGAGIPPPP-PLPGAGIL------------PLPPLPGAG---IPPPPPLPGAAIPPPP 957 Query: 110 AAPSPGPLPARPSSPPPS-PPSPPVPTAQSSLPAPWPPQGPRSPAP 154 P G +P P P PP PP+P A P P P G P P Sbjct: 958 PLPGAG-IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1002 Score = 37.7 bits (86), Expect = 0.004 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 12/83 (14%) Query: 89 GGDIASPLPPALQPRGAPAVP--AAPSPGPLPARPSSPPPSPP--------SPPVPTAQS 138 G + P PP L P +P A P P PL PPP PP PP+P A Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931 Query: 139 SLPAPWPPQG--PRSPAPSLRAP 159 P P G P P P P Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIP 954 Score = 37.0 bits (84), Expect = 0.007 Identities = 34/133 (25%), Positives = 46/133 (34%), Gaps = 16/133 (12%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97 P + LD +P + + PP P +A + P S Q ++S Sbjct: 791 PRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFK 850 Query: 98 PALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSP--PVPTAQSS-------------LPA 142 + P +P S +P PPP PP P VPT S+ LP Sbjct: 851 NSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP 910 Query: 143 PWPP-QGPRSPAP 154 P PP G P P Sbjct: 911 PPPPLPGAGIPPP 923 Score = 33.9 bits (76), Expect = 0.060 Identities = 39/127 (30%), Positives = 42/127 (33%), Gaps = 27/127 (21%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 PG P P L AG+ P P PP P P P P G Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP--------------PLPGVGIPPPPPLPG 1203 Query: 90 GDIASP-------LPPALQPRGAPAVPAAPSPGPLPARPSSPP--PSPPSPPVPTAQ--S 138 I P +PPA P P P P LP S PP P S +PT Q Sbjct: 1204 AGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPV--SGPPLLPQVGSSTLPTPQVCG 1261 Query: 139 SLPAPWP 145 LP P P Sbjct: 1262 FLPPPLP 1268 Score = 33.5 bits (75), Expect = 0.079 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 8/91 (8%) Query: 44 GLDGIRPAPAAAHPPAPRERPAAARLSALA------AAQPRRRSPGPQGGGGGDIASPLP 97 GLD P+ AP LSAL+ AA+PR P GG +P Sbjct: 248 GLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSL 307 Query: 98 PALQP--RGAPAVPAAPSPGPLPARPSSPPP 126 PA QP + +P+ A P P P ++ P Sbjct: 308 PAAQPAAKDSPSSTAFPFPEAGPGEEAAGAP 338 Score = 26.9 bits (58), Expect = 7.4 Identities = 33/140 (23%), Positives = 45/140 (32%), Gaps = 19/140 (13%) Query: 37 GPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAA-AQPRRRSPGPQGGGGGDIAS- 94 G L + +DG+ P PP P S ++ PRR S S Sbjct: 752 GGVLTLPPVDGLPGRPPC--PPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQ 809 Query: 95 -PLPPALQPRGAPAVPAAPSPGPLPA--------------RPSSPPPSPPSPPVPTAQSS 139 P PP+L P + P + + S PSPP P + SS Sbjct: 810 PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSS 869 Query: 140 LPAPWPPQGPRSPAPSLRAP 159 +P P P P + P Sbjct: 870 MPGLGMVPPPPPPLPGMTVP 889 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 59.3 bits (142), Expect = 1e-09 Identities = 43/136 (31%), Positives = 49/136 (36%), Gaps = 32/136 (23%) Query: 25 VGVGEPGGFCLPGPALVVAG-----LDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRR 79 V V P G P P + PAP AA PP P P Sbjct: 506 VAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPP----------------PLP 549 Query: 80 RSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSS-PPPSPPSPPVPTAQS 138 P PQ PP+ P+ AP +P +P P P P P PPP PP PP P Sbjct: 550 GLPSPQEA---------PPSAPPQ-APPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDG 599 Query: 139 SLPAPWPPQGPRSPAP 154 +P P PP P P Sbjct: 600 PVPPPPPPPPPPPGGP 615 Score = 42.7 bits (99), Expect = 1e-04 Identities = 37/119 (31%), Positives = 46/119 (38%), Gaps = 22/119 (18%) Query: 49 RPAPAAAHPPAPRERPAAARLSALAAAQPRR----RSPGPQGG-----------GGGDIA 93 RP PPA RP+A L + R PG GGD Sbjct: 458 RPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAP 517 Query: 94 SPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSP 152 +P P P +P + A P P A PPP PP P +P+ Q + P+ PPQ P P Sbjct: 518 TPGVPTGSP--SPDLAPAAEPAPGAA----PPPPPPLPGLPSPQEAPPSA-PPQAPPLP 569 Score = 27.7 bits (60), Expect = 4.3 Identities = 9/15 (60%), Positives = 12/15 (80%) Query: 118 PARPSSPPPSPPSPP 132 PA P++PPP P+PP Sbjct: 11 PAGPAAPPPKQPAPP 25 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 58.9 bits (141), Expect = 2e-09 Identities = 60/169 (35%), Positives = 65/169 (38%), Gaps = 28/169 (16%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPA-PAAAHPPAP 60 PGG A F RG G R PGG PGPA G G P PA PP P Sbjct: 189 PGGSSRAAFPQGGRGRG-----RFPGAVPGGDRFPGPA----GPGGPPPPFPAGQTPPRP 239 Query: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPAL---QPRGAPAVPAAPSPGPL 117 P P + P P G P PP L QP G P + P PGP Sbjct: 240 PLGPPGPP-GPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLP-PGPP 297 Query: 118 PARPS-SPPPSPP----SPPVPTAQSSLPAPWPPQ--GPRSPAPSLRAP 159 P P PPP PP PP P P P+PP+ GP P +L P Sbjct: 298 PPVPGYGPPPGPPPPQQGPPPP------PGPFPPRPPGPLGPPLTLAPP 340 Score = 41.2 bits (95), Expect = 4e-04 Identities = 32/111 (28%), Positives = 40/111 (36%), Gaps = 8/111 (7%) Query: 44 GLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPR 103 G + P P PP P P P++ P P G PL P L Sbjct: 285 GQPPLGPLPPGPPPPVPGYGPPPG------PPPPQQGPPPPPGPFPPRPPGPLGPPLTLA 338 Query: 104 GAPAVPAAPSPGPLPARPSSPP--PSPPSPPVPTAQSSLPAPWPPQGPRSP 152 P +P P P PA +P P P + +PT+ S P P P G P Sbjct: 339 PPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389 Score = 33.9 bits (76), Expect = 0.060 Identities = 34/123 (27%), Positives = 39/123 (31%), Gaps = 13/123 (10%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAH-----PPAPRERPAAARLSALAAAQPRRRSPGP 84 P G PGP V G G P P PP P L P PGP Sbjct: 288 PLGPLPPGPPPPVPGY-GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGP 346 Query: 85 QGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPP-------SPPSPPVPTAQ 137 G P P +P + S GP P P PP PP + TA+ Sbjct: 347 PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTAR 406 Query: 138 SSL 140 + L Sbjct: 407 TPL 409 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 58.5 bits (140), Expect = 2e-09 Identities = 40/119 (33%), Positives = 48/119 (40%), Gaps = 18/119 (15%) Query: 36 PGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASP 95 P P L A +G P P P PA QP+ P P P Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT-------PQPQPPPPPP----------P 1477 Query: 96 LPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 PAL P P V PS P P P PPP+ PSPP P ++ P PP+ P +P+P Sbjct: 1478 PQPAL-PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535 Score = 54.7 bits (130), Expect = 3e-08 Identities = 39/113 (34%), Positives = 44/113 (38%), Gaps = 14/113 (12%) Query: 58 PAPRERPAAARLSALAAAQPRRRSPG-PQGGGGGDIASPLPPALQPRGAPAVPAAPSPGP 116 P P L+ AA PG P G +P PP L+ + P P AP+P P Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNG---TPEPPLLEEKPPPTPPPAPTPQP 1469 Query: 117 LPARPSSPP----PSPPSPPVPTAQSSLPAPWPP------QGPRSPAPSLRAP 159 P P PP PSPP PT S P P PP P P P AP Sbjct: 1470 QPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP 1522 Score = 42.0 bits (97), Expect = 2e-04 Identities = 47/149 (31%), Positives = 56/149 (37%), Gaps = 24/149 (16%) Query: 4 GVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRER 63 G +AA G A GGG R + + PG G AG A PP PR Sbjct: 364 GPEAAGGGGAGGGGGGYRPI---IQSPGYKTGKGGYGAAAG--------GATRPPPPRST 412 Query: 64 --PAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPA--LQPR-------GAPAVPAAP 112 P L AAA ++ G GG GG SP P L P+ G A + Sbjct: 413 ATPKCQSLGGPAAAYATGKASGA-GGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSK 471 Query: 113 SPGPLPARPSSPPPSPPSPPVPTAQSSLP 141 +P P PP PP P + T QS P Sbjct: 472 APS-YSGGPPQPPSGPPPPGLATCQSYSP 499 Score = 38.9 bits (89), Expect = 0.002 Identities = 34/95 (35%), Positives = 42/95 (44%), Gaps = 20/95 (21%) Query: 82 PGPQG----GGGGDIASPLPPALQPRGAPAVPA-APSPGPLPA-----------RPSSP- 124 P P G GG D+ LPP P+ P+V + APSP P + R +P Sbjct: 776 PTPHGLLLEAGGPDLPLVLPPP-PPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQ 834 Query: 125 PPSPPSPPVPTAQSSLPAPWPPQG--PRSPAPSLR 157 PP PP PP P L A G P +P+P LR Sbjct: 835 PPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLR 869 Score = 37.4 bits (85), Expect = 0.005 Identities = 38/126 (30%), Positives = 44/126 (34%), Gaps = 13/126 (10%) Query: 31 GGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARL---SALAAAQPRRRSPGPQGG 87 GG L L A RP P PP PR P L S+ AAA + SP Sbjct: 210 GGGVLGPAGLGPAQTPPYRPGPPDP-PPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNF 268 Query: 88 GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQS--SLPAPWP 145 G P P PR + RP+S P PP PP Q S +P Sbjct: 269 SGAAPGPPPPERALPRQDTVIKHYQ-------RPASAQPPPPPPPAHALQHYLSCGGSYP 321 Query: 146 PQGPRS 151 G R+ Sbjct: 322 SMGHRA 327 Score = 36.2 bits (82), Expect = 0.012 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 83 GPQGGGGGDIASPLPPAL--QPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSL 140 GP G A P P L P P +P+ + PL S P + P PP P Sbjct: 991 GPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPA 1050 Query: 141 PAPWPPQGPRSP 152 PA P G SP Sbjct: 1051 PASEPKGGLTSP 1062 Score = 33.5 bits (75), Expect = 0.079 Identities = 28/91 (30%), Positives = 35/91 (38%), Gaps = 13/91 (14%) Query: 75 AQPRRRSPGPQGGGGGDIASPLPPALQP-------RGAPAVPAAPSPGPLPARPSSPPPS 127 A P P+ G G P PPA P R + A P P G P +P P + Sbjct: 965 AGPPEDEGDPKAGAG---PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPST 1021 Query: 128 PPSPPVPTAQSS---LPAPWPPQGPRSPAPS 155 + P+ QS P PP P PAP+ Sbjct: 1022 VNAEPLGLIQSGPHQAAPPPPPPPPPPPAPA 1052 Score = 32.3 bits (72), Expect = 0.18 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 6/78 (7%) Query: 72 LAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSP 131 + A +P R P P G + P + AP P AP+P P P P + P Sbjct: 1661 VCARKPWHRPPVPVRRSG---QAKNPVSAGGSSAPP-PKAPAPPPKPETPEKT--TSEKP 1714 Query: 132 PVPTAQSSLPAPWPPQGP 149 P T ++++P P P+ P Sbjct: 1715 PEQTPETAMPEPPAPEKP 1732 Score = 32.0 bits (71), Expect = 0.23 Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 8/99 (8%) Query: 40 LVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPA 99 L + L G P+P A P A A S A G GGGGG P Sbjct: 329 LACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGG-----YRPI 383 Query: 100 LQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQS 138 +Q +P A ++ PP P S P QS Sbjct: 384 IQ---SPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQS 419 Score = 29.6 bits (65), Expect = 1.1 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 19/117 (16%) Query: 55 AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP-------RGAPA 107 +H P+P P+A+++ + +P R PQ P PP P R Sbjct: 807 SHAPSPS--PSASKVG-VHLLEPATRDGAPQPPP----PPPPPPPPMPLQLEAHLRSHGL 859 Query: 108 VPAAPSPGPLPARPSSPPPSPPS-----PPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 PAAPSP P PP + P+P A P + PA + R+P Sbjct: 860 EPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSP 916 Score = 29.3 bits (64), Expect = 1.5 Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 6/63 (9%) Query: 77 PRRRS---PGPQGGGGGDIASPLPPALQPRGAPAVPA-APSPGPLPARPSSPPPSPPSPP 132 P RRS P GG P PA P+ P P S P P + P PP+P Sbjct: 1673 PVRRSGQAKNPVSAGGSSAPPPKAPAPPPK--PETPEKTTSEKPPEQTPETAMPEPPAPE 1730 Query: 133 VPT 135 P+ Sbjct: 1731 KPS 1733 Score = 26.9 bits (58), Expect = 7.4 Identities = 14/39 (35%), Positives = 17/39 (43%) Query: 116 PLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 PL +PP SPP P+ + P PP P P P Sbjct: 1297 PLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHP 1335 Score = 26.9 bits (58), Expect = 7.4 Identities = 24/75 (32%), Positives = 28/75 (37%), Gaps = 14/75 (18%) Query: 99 ALQPRGAPAVPAAPS---PGPLPARPSSPPP-----SPPSPPVPTAQSS------LPAPW 144 A +P P VP S P+ A SS PP PP P P +S P Sbjct: 1663 ARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETA 1722 Query: 145 PPQGPRSPAPSLRAP 159 P+ P PSL P Sbjct: 1723 MPEPPAPEKPSLLRP 1737 Score = 26.6 bits (57), Expect = 9.6 Identities = 28/93 (30%), Positives = 33/93 (35%), Gaps = 4/93 (4%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSP-GPQGGGGGDIASP---LPPALQPRGA 105 P PAA P P+ + + + A GP GGG ASP + P P Sbjct: 515 PGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPAT 574 Query: 106 PAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQS 138 P SPG SS S P P A S Sbjct: 575 GRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGS 607 Score = 26.6 bits (57), Expect = 9.6 Identities = 12/17 (70%), Positives = 13/17 (76%), Gaps = 1/17 (5%) Query: 127 SPPSPPVPTAQSSLPAP 143 SPP PP PTAQS+ P P Sbjct: 763 SPPPPP-PTAQSTQPTP 778 Score = 26.6 bits (57), Expect = 9.6 Identities = 29/103 (28%), Positives = 37/103 (35%), Gaps = 16/103 (15%) Query: 50 PAPAAAHPPAPRERPAAARLSAL--AAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107 P P PP P + A R L AA PR R + + P A+Q Sbjct: 837 PPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRP---------EESLDPPGAMQELLGAL 887 Query: 108 VPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPR 150 P P+PG PP S P +S P+P + PR Sbjct: 888 EPLPPAPGDTGV---GPPNSEGKDPAGAYRS--PSPQGTKAPR 925 Score = 26.6 bits (57), Expect = 9.6 Identities = 18/49 (36%), Positives = 20/49 (40%), Gaps = 5/49 (10%) Query: 78 RRRSPGPQGGGGGDIASPL-PPALQPRGAPAVPAAPSPGPLPARPSSPP 125 +R P Q G + PL PP P PA P P PA P PP Sbjct: 1293 KRHPPLYQAG----LTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337 Score = 26.6 bits (57), Expect = 9.6 Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 4/36 (11%) Query: 97 PPALQPRGAPAVPAAPSPGPLPARPSSP--PPSPPS 130 PP P+ P P+ P+ G P P++P P PPS Sbjct: 1305 PPLSPPKSVP--PSVPARGLQPQPPATPAVPHPPPS 1338 >gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] Length = 1240 Score = 58.2 bits (139), Expect = 3e-09 Identities = 38/111 (34%), Positives = 53/111 (47%), Gaps = 9/111 (8%) Query: 45 LDGIRPAPAAAHPPAPR-ERPAAARLSALAAAQPRRRSPGPQ-------GGGGGDIASPL 96 ++G +PA AAA P + + ++S A + + +P P G P Sbjct: 383 VEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPP 442 Query: 97 PPALQPRGAPAVPAAPSPGPLPARPSSPPPSPP-SPPVPTAQSSLPAPWPP 146 PP L GA A+P AP P PLP + PP+PP PP+P + LP P PP Sbjct: 443 PPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPP 493 Score = 49.3 bits (116), Expect = 1e-06 Identities = 39/107 (36%), Positives = 41/107 (38%), Gaps = 9/107 (8%) Query: 54 AAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPS 113 A+ PP P P SA P P P G +P PP L GA A PA P Sbjct: 418 ASTPPPPPPPPLLPGSSA-EPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPL 476 Query: 114 PGPLPAR----PSSPPPSP----PSPPVPTAQSSLPAPWPPQGPRSP 152 P PLP P PPP P P PP P P PP P P Sbjct: 477 PPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLP 523 Score = 36.2 bits (82), Expect = 0.012 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 9/112 (8%) Query: 49 RPAPAAAHPPAPRERPAAARL--SALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP 106 RP P+ P + A L S ++ +P P G A+ + + Sbjct: 347 RPRPS---PLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSE 403 Query: 107 AVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRA 158 ++ P L + S+PPP PP P +P + + P P PP P PS+ A Sbjct: 404 SILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPP----PPLPSVGA 451 >gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] Length = 1249 Score = 58.2 bits (139), Expect = 3e-09 Identities = 38/111 (34%), Positives = 53/111 (47%), Gaps = 9/111 (8%) Query: 45 LDGIRPAPAAAHPPAPR-ERPAAARLSALAAAQPRRRSPGPQ-------GGGGGDIASPL 96 ++G +PA AAA P + + ++S A + + +P P G P Sbjct: 383 VEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPP 442 Query: 97 PPALQPRGAPAVPAAPSPGPLPARPSSPPPSPP-SPPVPTAQSSLPAPWPP 146 PP L GA A+P AP P PLP + PP+PP PP+P + LP P PP Sbjct: 443 PPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPP 493 Score = 49.3 bits (116), Expect = 1e-06 Identities = 39/107 (36%), Positives = 41/107 (38%), Gaps = 9/107 (8%) Query: 54 AAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPS 113 A+ PP P P SA P P P G +P PP L GA A PA P Sbjct: 418 ASTPPPPPPPPLLPGSSA-EPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPL 476 Query: 114 PGPLPAR----PSSPPPSP----PSPPVPTAQSSLPAPWPPQGPRSP 152 P PLP P PPP P P PP P P PP P P Sbjct: 477 PPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLP 523 Score = 36.2 bits (82), Expect = 0.012 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 9/112 (8%) Query: 49 RPAPAAAHPPAPRERPAAARL--SALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP 106 RP P+ P + A L S ++ +P P G A+ + + Sbjct: 347 RPRPS---PLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSE 403 Query: 107 AVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRA 158 ++ P L + S+PPP PP P +P + + P P PP P PS+ A Sbjct: 404 SILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPP----PPLPSVGA 451 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 57.0 bits (136), Expect = 7e-09 Identities = 53/152 (34%), Positives = 60/152 (39%), Gaps = 14/152 (9%) Query: 6 QAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAA-AHPPAPRERP 64 Q R G + G G + VG P G +PG + GL G + AP H AP P Sbjct: 618 QQGRPGPSGVAGPQGEKGDVGPAGPPG--VPGSVVQQEGLKGEQGAPGPRGHQGAPG--P 673 Query: 65 AAARLSALAAAQPRRRSPGPQG--GGGGDIASPLPPALQ----PRGAPAVPAAPSPGPLP 118 AR + R PG QG G GD+ P P L P G P VP P PG P Sbjct: 674 PGAR--GPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731 Query: 119 ARPSSPP-PSPPSPPVPTAQSSLPAPWPPQGP 149 P P P PP PT P P GP Sbjct: 732 GLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGP 763 Score = 44.7 bits (104), Expect = 3e-05 Identities = 46/161 (28%), Positives = 57/161 (35%), Gaps = 11/161 (6%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGV----GEPGGFCLPGPALVV--AGLDGIRPAPAAA 55 P G Q R GA G G + GV G PG PG + AG GI+ +P Sbjct: 1166 PQGSQGER-GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224 Query: 56 HPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA----A 111 PP P+ + + R PGP G G LP RG P + Sbjct: 1225 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 1284 Query: 112 PSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSP 152 +PGP + P P + P PQGPR P Sbjct: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP 1325 Score = 41.2 bits (95), Expect = 4e-04 Identities = 43/133 (32%), Positives = 47/133 (35%), Gaps = 15/133 (11%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 GE G LPG L G R A P P P L P R PG QG Sbjct: 822 GEKGELGLPG-------LKGDRGEKGEAGPAGPPGLPGTTSLFT-----PHPRMPGEQGP 869 Query: 88 GG--GDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWP 145 G GD P P LQ R P P+ P +P + P A + AP P Sbjct: 870 KGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP 929 Query: 146 PQGPRS-PAPSLR 157 P S AP LR Sbjct: 930 SGPPGSVGAPGLR 942 Score = 39.3 bits (90), Expect = 0.001 Identities = 44/159 (27%), Positives = 58/159 (36%), Gaps = 28/159 (17%) Query: 1 MPGGVQAARFGAAVRGGG----AGRRVRVGVGEPGGFCLPG----PALVVAGLDGIRPAP 52 +PG + VRG G+ V+ G PG PG P + VAG P Sbjct: 997 LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAG------PP 1050 Query: 53 AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112 + PP + P + L PGPQG G D A P P G P + + Sbjct: 1051 GPSGPPGDKGSPGSRGLPGF---------PGPQGPAGRDGAPGNPGERGPPGKPGLSSLL 1101 Query: 113 SPGPLPARP----SSPPPSPPS-PPVPTAQSSLPAPWPP 146 SPG + + PP PP P +P + P P Sbjct: 1102 SPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP 1140 Score = 37.4 bits (85), Expect = 0.005 Identities = 29/100 (29%), Positives = 36/100 (36%), Gaps = 4/100 (4%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 GE G LPG + G DG P PR P +PG +G Sbjct: 1291 GESGAMGLPGQE-GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 1349 Query: 88 GGGDIASPLPPALQPRGAPAVP---AAPSPGPLPARPSSP 124 G + + LP L PRG P P P +P +P P Sbjct: 1350 KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP 1389 Score = 36.2 bits (82), Expect = 0.012 Identities = 53/180 (29%), Positives = 58/180 (32%), Gaps = 32/180 (17%) Query: 6 QAARFGAAVRGGGAGRRVRVGV----GEPGGFCLPGPALVVAGLDGIRPAPAAAH----- 56 Q GA G G VG G PG PG G DG R AA Sbjct: 905 QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG-LRGTPGKDGERGEKGAAGEEGSP 963 Query: 57 -PPAPRERPAAARLSALAA----AQPRRRS----PGPQGG--------GGGDIASPLPPA 99 P PR P A L +P R PGP G G + A Sbjct: 964 GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCV 1023 Query: 100 LQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSS---LPAPWPPQGP--RSPAP 154 RGAP +P +P P + PP P PP LP PQGP R AP Sbjct: 1024 KGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAP 1083 Score = 34.7 bits (78), Expect = 0.035 Identities = 32/97 (32%), Positives = 38/97 (39%), Gaps = 12/97 (12%) Query: 28 GEPGGFCLPGPALV--VAGLDGIRPAPAAA-HPPAPRE--RPAAARLSALAAAQPRRRSP 82 G PG GP G +G AP AA +P AP P + A R +P Sbjct: 886 GRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTP 945 Query: 83 GPQG-----GGGGDIASPLPPALQPRGAPAVPAAPSP 114 G G G G+ SP P + PRG P P P P Sbjct: 946 GKDGERGEKGAAGEEGSPGP--VGPRGDPGAPGLPGP 980 Score = 31.2 bits (69), Expect = 0.39 Identities = 32/121 (26%), Positives = 39/121 (32%), Gaps = 26/121 (21%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 GE G LPG G++ P P P P A A +PG G Sbjct: 871 GEKGDPGLPGEP-------GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGH 923 Query: 88 GGGDIASPLPPALQPRGAPAVPAAP----------------SPGPLPARPSSPPPSPPSP 131 G S P ++ GAP + P SPGP+ R P P P Sbjct: 924 VGAPGPSGPPGSV---GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGP 980 Query: 132 P 132 P Sbjct: 981 P 981 Score = 31.2 bits (69), Expect = 0.39 Identities = 39/129 (30%), Positives = 45/129 (34%), Gaps = 20/129 (15%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 G PG PGP G DG+ P A P RP L + GP+G Sbjct: 1497 GRPGP---PGPP----GKDGL---PGRAGPMGEPGRPGQGGLEGPSGPI------GPKGE 1540 Query: 88 GGGDIASPLPPALQPRGAPAVPAAP-SPG-PLPARPSSPP-PSPPSPPVPTAQSSLPAPW 144 G P P + RG P P PG P A+ P P P P LP P Sbjct: 1541 RGAK-GDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPP 1599 Query: 145 PPQGPRSPA 153 P G P+ Sbjct: 1600 GPPGQCDPS 1608 Score = 30.0 bits (66), Expect = 0.87 Identities = 32/119 (26%), Positives = 41/119 (34%), Gaps = 23/119 (19%) Query: 19 AGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPR 78 AG + +GV P G LPGP + I P A P P+ + + Sbjct: 480 AGEKGEMGVAGPMG--LPGPK---GDIGAIGPVGA----PGPKGEKGDVGIGPFGQGEKG 530 Query: 79 RRS----PGPQGGGGGDIASPLPPALQPRGAPAVPAAPS-PGPLPARPSSPPPSPPSPP 132 + PGP G G + RG P P PG + R PP P PP Sbjct: 531 EKGSLGLPGPPGRDG---------SKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPP 580 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 56.6 bits (135), Expect = 9e-09 Identities = 42/113 (37%), Positives = 48/113 (42%), Gaps = 10/113 (8%) Query: 53 AAAHPPAPRERP-------AAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGA 105 ++A PA E P ++A L AA +P QG G +A P PP L P A Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPA 324 Query: 106 PAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRA 158 A A P P P P P PP PP P LP PP P PAP L A Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPPPPP---PPLPNQVPPPPPPPPAPPLPA 374 Score = 52.0 bits (123), Expect = 2e-07 Identities = 30/87 (34%), Positives = 35/87 (40%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P AA PA L LA P PGP P PP P + P Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP 348 Query: 110 AAPSPGPLPARPSSPPPSPPSPPVPTA 136 P P PLP + PPP PP+PP+P + Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLPAS 375 Score = 44.3 bits (103), Expect = 4e-05 Identities = 35/102 (34%), Positives = 44/102 (43%), Gaps = 13/102 (12%) Query: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGA--PAVPAAPSPGPLP 118 RER L + RR S + +PL L A P + AA P P Sbjct: 245 RERQEQLEREQLEWERERRIS---SAAAPASVETPLNSVLGDSSASEPGLQAASQPAETP 301 Query: 119 AR------PSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 ++ P +PPP PP PP P AQ+S+ P PP GP P P Sbjct: 302 SQQGIVLGPLAPPPPPPLPPGP-AQASVALP-PPPGPPPPPP 341 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 56.6 bits (135), Expect = 9e-09 Identities = 42/113 (37%), Positives = 48/113 (42%), Gaps = 10/113 (8%) Query: 53 AAAHPPAPRERP-------AAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGA 105 ++A PA E P ++A L AA +P QG G +A P PP L P A Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPA 324 Query: 106 PAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRA 158 A A P P P P P PP PP P LP PP P PAP L A Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPPPPP---PPLPNQVPPPPPPPPAPPLPA 374 Score = 52.0 bits (123), Expect = 2e-07 Identities = 30/87 (34%), Positives = 35/87 (40%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P AA PA L LA P PGP P PP P + P Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPP 348 Query: 110 AAPSPGPLPARPSSPPPSPPSPPVPTA 136 P P PLP + PPP PP+PP+P + Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLPAS 375 Score = 44.3 bits (103), Expect = 4e-05 Identities = 35/102 (34%), Positives = 44/102 (43%), Gaps = 13/102 (12%) Query: 61 RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGA--PAVPAAPSPGPLP 118 RER L + RR S + +PL L A P + AA P P Sbjct: 245 RERQEQLEREQLEWERERRIS---SAAAPASVETPLNSVLGDSSASEPGLQAASQPAETP 301 Query: 119 AR------PSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 ++ P +PPP PP PP P AQ+S+ P PP GP P P Sbjct: 302 SQQGIVLGPLAPPPPPPLPPGP-AQASVALP-PPPGPPPPPP 341 >gi|169163027 PREDICTED: similar to Putative acrosin-like protease [Homo sapiens] Length = 355 Score = 56.2 bits (134), Expect = 1e-08 Identities = 35/91 (38%), Positives = 42/91 (46%), Gaps = 13/91 (14%) Query: 54 AAHPPAPRERPAAAR---LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA 110 +A PP P RP R L+A P P P+ P PPA QPR P+ P Sbjct: 233 SATPPPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRP------LPPRPPAAQPRPPPSPPP 286 Query: 111 APSPGPLPARPSSPPPSPPSPPVPTAQSSLP 141 P P P P PPP PP PP P++ + LP Sbjct: 287 PPPPPPSPL----PPPPPPPPPTPSSTTKLP 313 Score = 47.4 bits (111), Expect = 5e-06 Identities = 29/73 (39%), Positives = 38/73 (52%), Gaps = 12/73 (16%) Query: 97 PPALQPRGAPAVPA------APSPGPLPARPSS----PPPSPPSPPVPTAQSSLPAPWPP 146 PP ++P + + A P P PLP RP + PPPSPP PP P S LP P PP Sbjct: 243 PPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPP-PPPPSPLPPP-PP 300 Query: 147 QGPRSPAPSLRAP 159 P +P+ + + P Sbjct: 301 PPPPTPSSTTKLP 313 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 56.2 bits (134), Expect = 1e-08 Identities = 40/118 (33%), Positives = 45/118 (38%), Gaps = 11/118 (9%) Query: 52 PAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAA 111 P PPAP RP + L P P + G + PLP L P P P Sbjct: 411 PPLGPPPAPPLRPPGPP-TGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469 Query: 112 PSPGPLPARPSSPPPSPPSPPV-PTAQSSLPAP---------WPPQGPRSPAPSLRAP 159 P PGP P P PPP P P + P A +P P PP GP P AP Sbjct: 470 PPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAP 527 Score = 47.8 bits (112), Expect = 4e-06 Identities = 45/131 (34%), Positives = 49/131 (37%), Gaps = 24/131 (18%) Query: 36 PGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG-GDIAS 94 PGP G+ P P PP R + L PR PGP G G Sbjct: 424 PGPPT------GLPPGPPPGAPPFLRP----PGMPGLRGPLPRLLPPGPPPGRPPGPPPG 473 Query: 95 P---LPPALQPRG------APAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWP 145 P LPP PRG PA P P P P RP PP P+PP PAP P Sbjct: 474 PPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPP----GLFPPAPLP 529 Query: 146 PQGPRSPAPSL 156 G S P+L Sbjct: 530 NPGVLSAPPNL 540 Score = 44.7 bits (104), Expect = 3e-05 Identities = 30/106 (28%), Positives = 42/106 (39%), Gaps = 7/106 (6%) Query: 55 AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSP 114 A + ++ + + A ++++P PQ I +P P P G P P P Sbjct: 366 AEKQSQKQHKEESHSDGTSTASSQQQAP-PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424 Query: 115 GPLPARPSSPPPSPP----SPPVPTAQSSLPAPWPPQGP--RSPAP 154 GP P PPP P P +P + LP PP P R P P Sbjct: 425 GPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGP 470 Score = 36.6 bits (83), Expect = 0.009 Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 6/62 (9%) Query: 102 PRGAPA--VPAAPSPGPLP-ARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPA-PSLR 157 P+ P + A P PGP P P +PP PP P PT P P P R P P LR Sbjct: 394 PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGP--PTGLPPGPPPGAPPFLRPPGMPGLR 451 Query: 158 AP 159 P Sbjct: 452 GP 453 Score = 30.8 bits (68), Expect = 0.51 Identities = 19/55 (34%), Positives = 20/55 (36%), Gaps = 2/55 (3%) Query: 105 APAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 AP PS P P PP P PP P + P P GP AP P Sbjct: 392 APPQSVPPSQIQAPPMPGPPPLGP--PPAPPLRPPGPPTGLPPGPPPGAPPFLRP 444 Score = 29.3 bits (64), Expect = 1.5 Identities = 15/38 (39%), Positives = 18/38 (47%) Query: 122 SSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 SS +PP P+ + P P PP PAP LR P Sbjct: 387 SSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424 >gi|122937321 UNC homeobox [Homo sapiens] Length = 531 Score = 55.5 bits (132), Expect = 2e-08 Identities = 49/159 (30%), Positives = 60/159 (37%), Gaps = 33/159 (20%) Query: 18 GAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQP 77 G G + + +P GF +P AL G G+ PAP A PPAP PA ++ A Sbjct: 374 GKGHFLLYPITQPLGFLVPQAAL--KGGAGLEPAPKDA-PPAPAVPPAPPAQASFGAFS- 429 Query: 78 RRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP---------------------SPGP 116 GP G A P A+ GAPA AP + GP Sbjct: 430 -----GPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGP 484 Query: 117 LPARPSSPP---PSPPSPPVPTAQSSLPAPWPPQGPRSP 152 P P+ P P PPSP A +P P GP P Sbjct: 485 APPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPP 523 Score = 41.2 bits (95), Expect = 4e-04 Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 35/180 (19%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVV-----AGLDGIRP-APAAA 55 PG A + + G G R + C PG A+ AGL P + + Sbjct: 278 PGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESL 337 Query: 56 HPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP---------------PAL 100 +P R AA+ +A AAA G D A LP P Sbjct: 338 LSDSPPRRKAASNAAAAAAA-------------GLDFAPGLPCAPRTLIGKGHFLLYPIT 384 Query: 101 QPRGAPAVPAAPSPGP-LPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 QP G AA G L P PP+P PP P AQ+S A P G A + R+P Sbjct: 385 QPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSP 444 Score = 34.7 bits (78), Expect = 0.035 Identities = 24/69 (34%), Positives = 28/69 (40%), Gaps = 2/69 (2%) Query: 81 SPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPP-PSPPSPPVPTAQSS 139 S GGGG P PP +G P A+ + G PA P PP P P +Q S Sbjct: 233 SDSDSGGGGLSPEPPEPPPPAAKG-PGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRS 291 Query: 140 LPAPWPPQG 148 P P G Sbjct: 292 GAGPQPRPG 300 Score = 30.4 bits (67), Expect = 0.67 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%) Query: 97 PPALQPRGAPAVPAAPSPGPL-PARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSP 152 P L AP+ + G L P P PPP+ P + ++ AP PP P +P Sbjct: 222 PGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAP 278 Score = 30.0 bits (66), Expect = 0.87 Identities = 24/94 (25%), Positives = 32/94 (34%), Gaps = 13/94 (13%) Query: 43 AGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQP 102 +G G+ P P PP P + A S A +P P G P P P Sbjct: 237 SGGGGLSPEPPE--PPPPAAKGPGAHASGAAGT-----APAPPG------EPPAPGTCDP 283 Query: 103 RGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTA 136 P+ + P P P RP+ + P A Sbjct: 284 AFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVA 317 Score = 28.5 bits (62), Expect = 2.5 Identities = 36/124 (29%), Positives = 46/124 (37%), Gaps = 8/124 (6%) Query: 36 PGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG----GD 91 P P A G + AA PAP P A A +R GPQ G D Sbjct: 247 PEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKD 306 Query: 92 IASPLP---PALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQG 148 AS P A RGA +P A SP + + S PP + A ++ + P Sbjct: 307 AASCGPGAAVAAVERGAAGLPKA-SPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGL 365 Query: 149 PRSP 152 P +P Sbjct: 366 PCAP 369 >gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] Length = 651 Score = 55.5 bits (132), Expect = 2e-08 Identities = 55/149 (36%), Positives = 61/149 (40%), Gaps = 23/149 (15%) Query: 16 GGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARL-----S 70 GGG G GVG G PGPA G PAP PP P + AA RL S Sbjct: 10 GGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRP--PPEPDDAAAALRLALDQLS 67 Query: 71 ALA-----------AAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA-APSPGPLP 118 AL AA + G G GG P+PP GAP A A +PG LP Sbjct: 68 ALGLGGAGDTDEEGAAGDGAAAAG--GADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLP 125 Query: 119 ARP--SSPPPSPPSPPVPTAQSSLPAPWP 145 +SPPP PP P P + AP P Sbjct: 126 LLDPNASPPPPPPPRPSPPDVFAGFAPHP 154 Score = 35.4 bits (80), Expect = 0.021 Identities = 26/74 (35%), Positives = 28/74 (37%), Gaps = 21/74 (28%) Query: 84 PQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAP 143 P GGGGG G A PGP PA PP AQ + PAP Sbjct: 8 PDGGGGGGGG----------GGGVGAAGEDPGPGPA-----------PPPEGAQEAAPAP 46 Query: 144 WPPQGPRSPAPSLR 157 PP P A +LR Sbjct: 47 RPPPEPDDAAAALR 60 Score = 29.6 bits (65), Expect = 1.1 Identities = 33/124 (26%), Positives = 39/124 (31%), Gaps = 28/124 (22%) Query: 35 LPGPALVVAGLDGIRPAPA---------AAHPPA-----------PRERPAAARLSALAA 74 +P A + A + P PA A PPA PR P L Sbjct: 466 VPAAATIWAPFERAAPLPAFSGCSTVNGAPGPPAAGARRSSGAGTPRHSPTLPEPGGLRL 525 Query: 75 AQPRRRSPGPQGGGGGDIASPLPPALQPRGA--------PAVPAAPSPGPLPARPSSPPP 126 P R P G P P P GA P+ PAA + PL + S Sbjct: 526 ELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSR 585 Query: 127 SPPS 130 PPS Sbjct: 586 KPPS 589 Score = 29.3 bits (64), Expect = 1.5 Identities = 26/78 (33%), Positives = 29/78 (37%), Gaps = 2/78 (2%) Query: 7 AARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPA--PAAAHPPAPRERP 64 AA GAA GG G V G P L A G P P A+ PP P RP Sbjct: 82 AAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPPPPPPPRP 141 Query: 65 AAARLSALAAAQPRRRSP 82 + + A A P P Sbjct: 142 SPPDVFAGFAPHPAALGP 159 >gi|22027541 programmed cell death 7 [Homo sapiens] Length = 485 Score = 55.5 bits (132), Expect = 2e-08 Identities = 37/111 (33%), Positives = 46/111 (41%), Gaps = 19/111 (17%) Query: 50 PAPAAAHPPAPRERP------AAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPR 103 P P+ A PP +RP +A L A QPR + +GGGG P+PP Sbjct: 31 PLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGGGGAGAFYPVPP----- 85 Query: 104 GAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 P P P P P + P PP PP P PW P+ P +P P Sbjct: 86 -PPLPPPPPQCRPFPGTDAGERPRPP-PPGP------GPPWSPRWPEAPPP 128 Score = 35.4 bits (80), Expect = 0.021 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 95 PLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSP-PVPTAQSSLPAPWPPQGPRSPA 153 P PP QP P P P PLP+ P+ PPP P P P P A + P PR+ A Sbjct: 12 PGPPPPQP--PPPAPFGCPPPPLPS-PAFPPPLPQRPGPFPGASAPFLQPPLALQPRASA 68 Query: 154 PSLR 157 + R Sbjct: 69 EASR 72 Score = 32.3 bits (72), Expect = 0.18 Identities = 26/65 (40%), Positives = 29/65 (44%), Gaps = 9/65 (13%) Query: 96 LPPAL-QPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 LPP Q R P P P P P P P PSP PP P Q P P+ P + AP Sbjct: 3 LPPFFGQGRPGPPPPQPPPPAPFGC-PPPPLPSPAFPP-PLPQR--PGPF----PGASAP 54 Query: 155 SLRAP 159 L+ P Sbjct: 55 FLQPP 59 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 55.1 bits (131), Expect = 3e-08 Identities = 43/129 (33%), Positives = 51/129 (39%), Gaps = 12/129 (9%) Query: 33 FCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDI 92 F P P L + + I PP P P A L A +P P P + Sbjct: 740 FSAPPPPLKIHQVQHITQVAPPTPPPPP---PIPAPLPPQAPPKPLVTIPAPTSTK--TV 794 Query: 93 ASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLP-----APWPPQ 147 A + A P P VP A PA S PPSPP+PPVP +LP PP Sbjct: 795 APVVTQAAPPTPTPPVPPAKKQPAFPA--SYIPPSPPTPPVPVPPPTLPKQQSFCAKPPP 852 Query: 148 GPRSPAPSL 156 P SP PS+ Sbjct: 853 SPLSPVPSV 861 Score = 48.9 bits (115), Expect = 2e-06 Identities = 44/153 (28%), Positives = 53/153 (34%), Gaps = 43/153 (28%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAA------QPRRRSPGPQGGGGGDIASPLPPALQ-- 101 P P PP P P+ + SA +AA R G P PP +Q Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQ 695 Query: 102 ---------PRGA----PAVPAAPSPG-------PLPARPSSPP---PSPP--------- 129 P G P P P+PG P P PS P P PP Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHI 755 Query: 130 ---SPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 +PP P +PAP PPQ P P ++ AP Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAP 788 Score = 45.4 bits (106), Expect = 2e-05 Identities = 43/117 (36%), Positives = 52/117 (44%), Gaps = 18/117 (15%) Query: 52 PAAAHPPAPRERPAAARLSALAAAQPRRRSP-GPQGGGGGDIAS-----PLPPALQPRGA 105 P+ PP P P + + A P SP P IAS P PPA++ + Sbjct: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPP--SPLSPVPSVVKQIASQFPPPPTPPAMESQPL 883 Query: 106 PAVPAAPSPGPLPA-------RPSS-PPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 VPA +P PA +PSS P PSP PP P +SSL P PP P PAP Sbjct: 884 KPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPP-PPPESSLVFPPPPPSP-VPAP 938 Score = 39.3 bits (90), Expect = 0.001 Identities = 23/60 (38%), Positives = 24/60 (40%), Gaps = 8/60 (13%) Query: 96 LPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPS 155 L P L P+ P S P P PPP PP PP P P PP P APS Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPP--------PPPPPPPLPSQSAPS 656 Score = 39.3 bits (90), Expect = 0.001 Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 10/129 (7%) Query: 33 FCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDI 92 FC P ++ + + A+ PP P P A L +P + PQ Sbjct: 846 FCAKPPPSPLSPVPSVVKQIASQFPPPPT--PPAMESQPL---KPVPANVAPQSPPAVKA 900 Query: 93 ASPLPPALQPRGAPAVPAAPSPGPL--PARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPR 150 P+ P +P P P L P P SP P+PP PP PTA P P P Sbjct: 901 KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS---PTPDKSGSPG 957 Query: 151 SPAPSLRAP 159 +P Sbjct: 958 KKTSKTSSP 966 Score = 38.9 bits (89), Expect = 0.002 Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 4/44 (9%) Query: 94 SPLPPALQPRGA--PAVPAAPSPGPLPARPSSPPPSPPSPPVPT 135 SP P + P A P+ P P P P P P PPP PP PP+P+ Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPPPPP--PPPPPPPPPPPPLPS 651 Score = 38.1 bits (87), Expect = 0.003 Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 16/120 (13%) Query: 48 IRPAPAAAHPPAPRERPAAARL--SALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGA 105 ++P PA P +P A + S++ P P P+ + P PP P A Sbjct: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS----LVFPPPPP-SPVPA 937 Query: 106 PAVPAAPSPGPLPARPSSP---------PPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSL 156 P P P+ P P + SP P PP P SS+ + + P PS+ Sbjct: 938 PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 Score = 35.8 bits (81), Expect = 0.016 Identities = 31/112 (27%), Positives = 35/112 (31%), Gaps = 38/112 (33%) Query: 81 SPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPS------------- 127 SP P+ + P PP P P P P P P P PS PS Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669 Query: 128 ----------------PPSPPVPTAQSSLP---------APWPPQGPRSPAP 154 PP+PPV +QS P P PP P P P Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTP 721 Score = 32.7 bits (73), Expect = 0.13 Identities = 20/61 (32%), Positives = 24/61 (39%), Gaps = 1/61 (1%) Query: 100 LQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPV-PTAQSSLPAPWPPQGPRSPAPSLRA 158 ++ P P P P + S PSPP+ P P P PP P P PS A Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSA 654 Query: 159 P 159 P Sbjct: 655 P 655 Score = 32.3 bits (72), Expect = 0.18 Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 16/110 (14%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P+ PPA +P LS + PG G S P L RG +V Sbjct: 1013 PSKETLPPPAAPPKPGKLNLSGV-------NLPGVLQQG---CVSAKAPVLSGRGKDSVV 1062 Query: 110 AAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 PSP P+ PPP PP +P +PA + G SP ++ P Sbjct: 1063 EFPSP---PSDSDFPPP-PPETELPLPPIEIPAVF--SGNTSPKVAVVNP 1106 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 55.1 bits (131), Expect = 3e-08 Identities = 44/157 (28%), Positives = 56/157 (35%), Gaps = 35/157 (22%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRE-----RPAAARLSALAAAQPRRRSPGPQGGGGGDI 92 P L GL G +P A PP P P A+ S+L + P P G I Sbjct: 591 PTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI 650 Query: 93 ASPL-----------------PPALQPRGA-PAVPAAPSPGPLPARPSSPPPSPPSPPVP 134 +PL PP +PR PA PA +P +P S+ SP SPP P Sbjct: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTP 710 Query: 135 ------------TAQSSLPAPWPPQGPRSPAPSLRAP 159 ++ P P PP P P + P Sbjct: 711 QTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKP 747 Score = 38.1 bits (87), Expect = 0.003 Identities = 27/112 (24%), Positives = 39/112 (34%), Gaps = 3/112 (2%) Query: 36 PGPALVVAGLDGIRPAPAAAHPPAPRERPAA-ARLSALAAAQPRRRSPGPQGGGGGDIAS 94 P PA + P P + +P+ P L+ L + + P Sbjct: 680 PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHP 739 Query: 95 PLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPP 146 P PP +P P+A P + + PP P PP P Q A +PP Sbjct: 740 PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPP--PPAPEEQDLSMADFPP 789 Score = 37.7 bits (86), Expect = 0.004 Identities = 32/118 (27%), Positives = 43/118 (36%), Gaps = 30/118 (25%) Query: 52 PAAAHPPAPR--------ERPAAARLSALAAAQPRRRSPGPQGGGGGD------------ 91 P + HPP P E P+A+ + P P P D Sbjct: 734 PPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEA 793 Query: 92 ---IASPLPPALQPRGAPAVPAAP-----SPGPLPARPSSPPPSPPSPPVPTAQSSLP 141 +ASP P P G+P + ++P S L +P P PP+PP P SS P Sbjct: 794 FFSVASPEPAG--PSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAP 849 Score = 37.7 bits (86), Expect = 0.004 Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 6/101 (5%) Query: 48 IRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG---GDIASPL--PPALQP 102 I+P + PPAP A+ A P++ G GGG D+ +PL P LQ Sbjct: 827 IQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQM 886 Query: 103 RGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAP 143 +V AP P PA S P P + S +PAP Sbjct: 887 VRLRSV-GAPGGAPTPALGPSAPQKPLRRALSGRASPVPAP 926 Score = 35.0 bits (79), Expect = 0.027 Identities = 27/97 (27%), Positives = 36/97 (37%), Gaps = 16/97 (16%) Query: 76 QPRRRSPGPQGGGGGDIASPLPP--------ALQPRGAPAVPAAPSPGPLPA-------- 119 QP+ P GG G A+P PP L P G+ P +P P+ Sbjct: 530 QPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSG 589 Query: 120 RPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSL 156 P+ PP PP ++ P P RSP S+ Sbjct: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASV 626 Score = 32.7 bits (73), Expect = 0.13 Identities = 35/120 (29%), Positives = 44/120 (36%), Gaps = 23/120 (19%) Query: 42 VAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG------GGGDIASP 95 VA L P + PRE A ++ R RS G GG G P Sbjct: 852 VAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKP 911 Query: 96 LPPALQPRGAPAVPA----------------APSPGPLPARPSSPPPSPPSPPVPTAQSS 139 L AL R +P VPA A S G A+P+ PP + P PP A ++ Sbjct: 912 LRRALSGRASP-VPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTA 970 Score = 31.6 bits (70), Expect = 0.30 Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 14/99 (14%) Query: 57 PPAPRERPAAARLSALAAAQPRRR-----SPGPQGGGGG-DIASPLPPALQPRGAPAVPA 110 PP P P LS P SP P G G ++ S PA A A+ Sbjct: 770 PPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSS--PAASSSSATALQI 827 Query: 111 APSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGP 149 P P PPP+PP+P ++ A P + P Sbjct: 828 QPPGSP------DPPPAPPAPAPASSAPGHVAKLPQKEP 860 Score = 29.6 bits (65), Expect = 1.1 Identities = 27/109 (24%), Positives = 42/109 (38%), Gaps = 9/109 (8%) Query: 44 GLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRR-----SPGPQGGGGGDIASPLPP 98 GL +P P P + PA+ + + + SP Q ++ + L Sbjct: 946 GLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRS 1005 Query: 99 ALQPRGAPAVPAAP-SPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPP 146 + R A +P +P P+ +PS P P SP P A+ P PP Sbjct: 1006 ISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAE---PLTAPP 1051 Score = 28.9 bits (63), Expect = 1.9 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 18/101 (17%) Query: 57 PPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGP 116 PP P R + LA GP G LPP + + P +P P+ G Sbjct: 497 PPPPPRRTHSLHQRGLAVPD------GPLG---------LPPKPERKQQPQLPRPPTTGG 541 Query: 117 LPARPSSP-PPSPPSPPVPTAQSSLPAPWPPQGP-RSPAPS 155 ++P PP+P + VP S + PP+ P R+ +PS Sbjct: 542 SEGAGAAPCPPNPANSWVP-GLSPGGSRRPPRSPERTLSPS 581 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 54.7 bits (130), Expect = 3e-08 Identities = 33/88 (37%), Positives = 42/88 (47%), Gaps = 10/88 (11%) Query: 69 LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSP 128 + +A+ Q + P P AS PP P G ++ AP P+ A P PPP P Sbjct: 634 MEGMASNQQKALPPPP--------ASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP 685 Query: 129 PSPPVPTAQSSLPAPWPPQG--PRSPAP 154 P PP+P S+ P P PP P SPAP Sbjct: 686 PPPPLPPPSSAGPPPPPPPPPLPNSPAP 713 Score = 54.7 bits (130), Expect = 3e-08 Identities = 42/112 (37%), Positives = 44/112 (39%), Gaps = 28/112 (25%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P P A+ PP P P P G G A P+PP G P P Sbjct: 646 PPPPASIPPPP---------------------PLPSGLGSLSPAPPMPPV--SAGPPLPP 682 Query: 110 AAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQG--PRSPAPSLRAP 159 P P PLP PSS P PP PP P S PAP P G P P P L P Sbjct: 683 PPPPPPPLPP-PSSAGPPPPPPPPPLPNS--PAPPNPGGPPPAPPPPGLAPP 731 Score = 44.7 bits (104), Expect = 3e-05 Identities = 37/116 (31%), Positives = 44/116 (37%), Gaps = 20/116 (17%) Query: 35 LPGPALVVAGLDGIRPAP----AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGG 90 +P P + +GL + PAP +A PP P P L ++A P P P Sbjct: 652 IPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGP----PPP------ 701 Query: 91 DIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPP 146 P PP L AP P P P P P P PP PP SS P P Sbjct: 702 ----PPPPPLPNSPAPPNPGGPPPAPPP--PGLAPPPPPGLFFGLGSSSSQCPRKP 751 Score = 39.3 bits (90), Expect = 0.001 Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 10/124 (8%) Query: 30 PGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGG 89 P G PA + + P P PP P P++A P SP P GG Sbjct: 659 PSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGG 718 Query: 90 GDIASPLPPALQPRGAPAV--PAAPSPGPLPARPSSPPPSPPSPPVPT-------AQSSL 140 A P PP L P P + S P +P+ P P P T +Q++ Sbjct: 719 PPPAPP-PPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNAT 777 Query: 141 PAPW 144 P W Sbjct: 778 PTLW 781 Score = 37.4 bits (85), Expect = 0.005 Identities = 25/69 (36%), Positives = 29/69 (42%), Gaps = 8/69 (11%) Query: 99 ALQPRGAPAVPAAPSPGPLPARPSSPPPSP-------PSPPVPTAQSSLPAPWPPQGPRS 151 ALQP A + P PA PPP P P+PP+P + P P PP P Sbjct: 630 ALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPP 689 Query: 152 -PAPSLRAP 159 P PS P Sbjct: 690 LPPPSSAGP 698 >gi|85815829 SH3-domain binding protein 1 [Homo sapiens] Length = 701 Score = 54.7 bits (130), Expect = 3e-08 Identities = 45/126 (35%), Positives = 53/126 (42%), Gaps = 29/126 (23%) Query: 50 PAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP 109 P PA PAP PA A A AA + R S P P P + + +P Sbjct: 505 PTPATTPAPAPAPAPAPAPALASAATKERTESEVP----------PRPASPKVTRSPPET 554 Query: 110 AAP-------SPGPLPARPSSPPP-------SPPSPPVPTAQSSLPAPWPPQG--PRSPA 153 AAP + P PARP+ PPP SPP+PP+P S P PQ R Sbjct: 555 AAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGS---PGTPQALPRRLVG 611 Query: 154 PSLRAP 159 SLRAP Sbjct: 612 SSLRAP 617 Score = 54.7 bits (130), Expect = 3e-08 Identities = 43/137 (31%), Positives = 52/137 (37%), Gaps = 16/137 (11%) Query: 36 PGPALVVAGL-----DGIRPAPAAAHPPAPRERPAAA--------RLSALAAAQPRRRSP 82 P PAL A + P PA+ P R P A R A A+P P Sbjct: 521 PAPALASAATKERTESEVPPRPAS--PKVTRSPPETAAPVEDMARRTKRPAPARPTMPPP 578 Query: 83 GPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPA 142 G A PLPP G P G P+ PPP PP+PP P + S + Sbjct: 579 QVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRS 638 Query: 143 PWPPQGPRSPAPSLRAP 159 P P P SP P+ +P Sbjct: 639 PASP-SPASPGPASPSP 654 Score = 38.9 bits (89), Expect = 0.002 Identities = 29/88 (32%), Positives = 34/88 (38%), Gaps = 8/88 (9%) Query: 51 APAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA 110 AP P P A R S + A P SPGP ASP P +L + A Sbjct: 616 APTVPPPLPPTPPQPARRQSRRSPASPSPASPGP--------ASPSPVSLSNPAQVDLGA 667 Query: 111 APSPGPLPARPSSPPPSPPSPPVPTAQS 138 A + G P S P P PP P +S Sbjct: 668 ATAEGGAPEAISGVPTPPAIPPQPRPRS 695 Score = 31.6 bits (70), Expect = 0.30 Identities = 22/75 (29%), Positives = 26/75 (34%), Gaps = 11/75 (14%) Query: 96 LPPALQPRGAPAVPAAPSPGPLPA-----------RPSSPPPSPPSPPVPTAQSSLPAPW 144 LP P A AP+P P PA S PP P SP V + AP Sbjct: 499 LPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPV 558 Query: 145 PPQGPRSPAPSLRAP 159 R+ P+ P Sbjct: 559 EDMARRTKRPAPARP 573 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 54.3 bits (129), Expect = 4e-08 Identities = 49/140 (35%), Positives = 59/140 (42%), Gaps = 27/140 (19%) Query: 35 LPGPALVVAGLDGIRPAPAAAHPP--APRERPAAARLSALAAAQPRRR------------ 80 LP P L + PA A PP AP PA+ LS LA P+ Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440 Query: 81 SPGPQGGGGGDIASPL-PPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSS 139 SP P + +P PPA P A P + +P L A P PPSPP+ P P + S+ Sbjct: 441 SPPPSP----PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSA 495 Query: 140 LPAPWPPQGPRSPAPSLRAP 159 P PPQ P P L AP Sbjct: 496 TP---PPQAP----PPLAAP 508 Score = 45.8 bits (107), Expect = 2e-05 Identities = 48/156 (30%), Positives = 60/156 (38%), Gaps = 35/156 (22%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDI----A 93 P+L L + P+P A+ P +P P LAA + P PQ A Sbjct: 472 PSLAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 530 Query: 94 SPLPPALQPRGAPAVPAAPSP-GPLPARPSSPPP-----------SPPS---------PP 132 P PPA P AP P+A P PL P PP SPP+ PP Sbjct: 531 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 590 Query: 133 VPTAQSSLP--------APWPPQGP-RSPAPSLRAP 159 P +S+ AP PP P RSP+ +L P Sbjct: 591 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626 Score = 44.7 bits (104), Expect = 3e-05 Identities = 43/134 (32%), Positives = 58/134 (43%), Gaps = 27/134 (20%) Query: 50 PAPAAAHPPAPR---ERPAAARLSALAA--AQPRRRSPGPQGGGGGDI--ASPLPPALQP 102 P+PAA P+ +RPA+ LS+ A + P R P +G + P P LQ Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279 Query: 103 RGAPAVP-----AAPSPGPLPARP-----------SSPPPSPPSPPVP---TAQSSLPAP 143 P V AAP+ GPL + P S PP+ P+ P T Q + P P Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLP 339 Query: 144 WPPQGPRSPAPSLR 157 P P +P PSL+ Sbjct: 340 LAPPSPSAP-PSLQ 352 Score = 44.3 bits (103), Expect = 4e-05 Identities = 40/124 (32%), Positives = 52/124 (41%), Gaps = 10/124 (8%) Query: 37 GPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL 96 GP L +A G P P+ + P + P A S+ A + P G GG ASP Sbjct: 600 GPRLTLALAPGPPPPPSRS-PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 658 Query: 97 PPALQPRGAPAVPAAPSPGPLP-----ARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRS 151 P A A PAA S GP P P +P P PP+ P + L + +GP S Sbjct: 659 PDA---ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGPES 714 Query: 152 PAPS 155 P+ Sbjct: 715 ATPA 718 Score = 40.4 bits (93), Expect = 6e-04 Identities = 36/109 (33%), Positives = 45/109 (41%), Gaps = 4/109 (3%) Query: 50 PAPAAA-HPPAPRERPAAARLSALAA--AQPRRRSPGPQGGGGGDIASPLPPALQPRGAP 106 P+P+AA AP PA S+L A P +P P PPA P A Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT 366 Query: 107 AVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPS 155 +P+ + SPP SP + P P A +L P P Q P SP S Sbjct: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP-PLQAPPSPPAS 414 Score = 40.0 bits (92), Expect = 8e-04 Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 11/115 (9%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97 PA GL + P P + P P PAA R+ A A R+ GG GG Sbjct: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG------- 67 Query: 98 PALQPRGAPAVPAAPSPGPLPARPSS-PPPSPPSPPVPTAQSSLPAPWPPQGPRS 151 A P AP S G P+S PP S P A+++ P P G S Sbjct: 68 -ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121 Score = 40.0 bits (92), Expect = 8e-04 Identities = 50/164 (30%), Positives = 63/164 (38%), Gaps = 31/164 (18%) Query: 19 AGRRVRVGVGEPGGFCLPGPALV----VAGLD-GI-RPAPAAA-HPPAPRERPAAARLSA 71 AG R PG P PA+ AG + G+ RPAP+A PP R + + S Sbjct: 158 AGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214 Query: 72 LAAAQPR---RRSPGPQGG-----------GGGDIASPLPPALQPRGAPAVPAAPS---P 114 + +P RR P GG ++SP RG P PA PS P Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274 Query: 115 GPLPA--RPSSPPPSPPSPPV--PTAQSSLPAPWPPQGPRSPAP 154 L A P PP + P P + S L P P +S AP Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318 Score = 31.2 bits (69), Expect = 0.39 Identities = 35/126 (27%), Positives = 45/126 (35%), Gaps = 14/126 (11%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 G G PGP G G+R + A A + A + SAL+A RR + GP G Sbjct: 118 GRASGTTRPGPL----GQKGLRIS--AEETVARGKATEAPKRSALSAGA-RRDTSGPTPG 170 Query: 88 GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQ 147 PA+ R A P P P+ PP P V +A P Sbjct: 171 TPS-------PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 223 Query: 148 GPRSPA 153 R P+ Sbjct: 224 ARRRPS 229 Score = 29.3 bits (64), Expect = 1.5 Identities = 36/131 (27%), Positives = 45/131 (34%), Gaps = 31/131 (23%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL- 96 PAL L + PA+ AP A+ +S LA P+ +A+PL Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV---------LAAPLL 571 Query: 97 -----PPALQPRGAPAVPAAP---------------SPGPLPARPSSPPPSPPSPPVPTA 136 PPA AP P P +PGP P PS P S S P Sbjct: 572 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP-PSRSPSSTLSGPDLAG 630 Query: 137 QSSLPAPWPPQ 147 SS P + Sbjct: 631 HSSSATSTPEE 641 Score = 28.5 bits (62), Expect = 2.5 Identities = 15/29 (51%), Positives = 16/29 (55%), Gaps = 1/29 (3%) Query: 105 APAVPAAPSPGPL-PARPSSPPPSPPSPP 132 A PAA +PG L P P SP P PP P Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTP 41 Score = 26.6 bits (57), Expect = 9.6 Identities = 21/66 (31%), Positives = 22/66 (33%), Gaps = 1/66 (1%) Query: 53 AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112 AA HP A PA A P P G G D + P A P A Sbjct: 664 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT-GPGSADGLCTIYETEGPESATPAPGAL 722 Query: 113 SPGPLP 118 PGP P Sbjct: 723 DPGPSP 728 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 54.3 bits (129), Expect = 4e-08 Identities = 49/140 (35%), Positives = 59/140 (42%), Gaps = 27/140 (19%) Query: 35 LPGPALVVAGLDGIRPAPAAAHPP--APRERPAAARLSALAAAQPRRR------------ 80 LP P L + PA A PP AP PA+ LS LA P+ Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401 Query: 81 SPGPQGGGGGDIASPL-PPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSS 139 SP P + +P PPA P A P + +P L A P PPSPP+ P P + S+ Sbjct: 402 SPPPSP----PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSA 456 Query: 140 LPAPWPPQGPRSPAPSLRAP 159 P PPQ P P L AP Sbjct: 457 TP---PPQAP----PPLAAP 469 Score = 46.2 bits (108), Expect = 1e-05 Identities = 55/189 (29%), Positives = 73/189 (38%), Gaps = 52/189 (27%) Query: 19 AGRRVRVGVGEPGGFCLPGPALV----VAGLD-GI-RPAPAAA-HPPAPRERPAAARLSA 71 AG R PG P PA+ AG + G+ RPAP+A PP R + + S Sbjct: 149 AGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 Query: 72 LAAAQPR---RRSPGPQGG-----------GGGDIASPLPPALQPRGAPAVP-------- 109 + +P RR P GG ++SP RG P P Sbjct: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 265 Query: 110 -----------------AAPSPGPLPARP-SSPPPS-PPSPPVPTAQSSLPAPWPPQGPR 150 AAP+ GPL + P ++P PS PPSP P + +LP+P P P Sbjct: 266 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP-PATPPS 324 Query: 151 SPAPSLRAP 159 SL +P Sbjct: 325 QATTSLGSP 333 Score = 45.8 bits (107), Expect = 2e-05 Identities = 48/156 (30%), Positives = 60/156 (38%), Gaps = 35/156 (22%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDI----A 93 P+L L + P+P A+ P +P P LAA + P PQ A Sbjct: 433 PSLAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491 Query: 94 SPLPPALQPRGAPAVPAAPSP-GPLPARPSSPPP-----------SPPS---------PP 132 P PPA P AP P+A P PL P PP SPP+ PP Sbjct: 492 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551 Query: 133 VPTAQSSLP--------APWPPQGP-RSPAPSLRAP 159 P +S+ AP PP P RSP+ +L P Sbjct: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587 Score = 45.4 bits (106), Expect = 2e-05 Identities = 53/159 (33%), Positives = 67/159 (42%), Gaps = 49/159 (30%) Query: 50 PAPAAAHPPAPR---ERPAAARLSALAA--AQPRRRSPGPQGGGGGDI--ASPLPPALQP 102 P+PAA P+ +RPA+ LS+ A + P R P +G + P P LQ Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270 Query: 103 RGAPAVP-----AAPSPGPL------------PARPSSPP-----PSPPSPPV------- 133 P V AAP+ GPL P PS+PP PSPP+ P Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330 Query: 134 --PTAQ---SSLPAP-------WPPQGPRSPA-PSLRAP 159 PT Q S LP+P PPQ P + A P L+AP Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 369 Score = 45.1 bits (105), Expect = 3e-05 Identities = 36/112 (32%), Positives = 44/112 (39%), Gaps = 3/112 (2%) Query: 44 GLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPR 103 GL +RP PP PA LS+ A P +P P PPA P Sbjct: 267 GLQALRPPQVT--PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPS 324 Query: 104 GAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPS 155 A +P+ + SPP SP + P P A +L P P Q P SP S Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP-PLQAPPSPPAS 375 Score = 44.3 bits (103), Expect = 4e-05 Identities = 40/124 (32%), Positives = 52/124 (41%), Gaps = 10/124 (8%) Query: 37 GPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL 96 GP L +A G P P+ + P + P A S+ A + P G GG ASP Sbjct: 561 GPRLTLALAPGPPPPPSRS-PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619 Query: 97 PPALQPRGAPAVPAAPSPGPLP-----ARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRS 151 P A A PAA S GP P P +P P PP+ P + L + +GP S Sbjct: 620 PDA---ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGPES 675 Query: 152 PAPS 155 P+ Sbjct: 676 ATPA 679 Score = 37.7 bits (86), Expect = 0.004 Identities = 35/114 (30%), Positives = 42/114 (36%), Gaps = 18/114 (15%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLP 97 PA GL + P P + P P PAA R+ A A R+ GG GG Sbjct: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG------- 67 Query: 98 PALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRS 151 A P AP P R S PP S P A+++ P P G S Sbjct: 68 -ATIPESAPRAG--------PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRAS 112 Score = 31.2 bits (69), Expect = 0.39 Identities = 35/126 (27%), Positives = 45/126 (35%), Gaps = 14/126 (11%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 G G PGP G G+R + A A + A + SAL+A RR + GP G Sbjct: 109 GRASGTTRPGPL----GQKGLRIS--AEETVARGKATEAPKRSALSAGA-RRDTSGPTPG 161 Query: 88 GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQ 147 PA+ R A P P P+ PP P V +A P Sbjct: 162 TPS-------PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 214 Query: 148 GPRSPA 153 R P+ Sbjct: 215 ARRRPS 220 Score = 29.3 bits (64), Expect = 1.5 Identities = 36/131 (27%), Positives = 45/131 (34%), Gaps = 31/131 (23%) Query: 38 PALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL- 96 PAL L + PA+ AP A+ +S LA P+ +A+PL Sbjct: 482 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV---------LAAPLL 532 Query: 97 -----PPALQPRGAPAVPAAP---------------SPGPLPARPSSPPPSPPSPPVPTA 136 PPA AP P P +PGP P PS P S S P Sbjct: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP-PSRSPSSTLSGPDLAG 591 Query: 137 QSSLPAPWPPQ 147 SS P + Sbjct: 592 HSSSATSTPEE 602 Score = 28.5 bits (62), Expect = 2.5 Identities = 15/29 (51%), Positives = 16/29 (55%), Gaps = 1/29 (3%) Query: 105 APAVPAAPSPGPL-PARPSSPPPSPPSPP 132 A PAA +PG L P P SP P PP P Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTP 41 Score = 26.6 bits (57), Expect = 9.6 Identities = 21/66 (31%), Positives = 22/66 (33%), Gaps = 1/66 (1%) Query: 53 AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP 112 AA HP A PA A P P G G D + P A P A Sbjct: 625 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT-GPGSADGLCTIYETEGPESATPAPGAL 683 Query: 113 SPGPLP 118 PGP P Sbjct: 684 DPGPSP 689 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 54.3 bits (129), Expect = 4e-08 Identities = 52/169 (30%), Positives = 63/169 (37%), Gaps = 30/169 (17%) Query: 4 GVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAP--- 60 G + A G A G A R G G PG PGP G P P P P Sbjct: 149 GPEPAPAGPAKPAGPAALAARAGPG-PG----PGP--------GPGPGPGPGKPAGPGAA 195 Query: 61 ----------RERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA 110 AAA +L P P P+ G + P AP PA Sbjct: 196 QTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQT--PPFVGAAAPPAPA 253 Query: 111 APSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 APSP PA P++P +PP PP P + P P GP + AP++ P Sbjct: 254 APSPPAAPA-PAAPAAAPP-PPPPAPATLARPPGHPAGPPTAAPAVPPP 300 Score = 51.2 bits (121), Expect = 4e-07 Identities = 54/166 (32%), Positives = 66/166 (39%), Gaps = 23/166 (13%) Query: 7 AARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAA 66 AAR G G G G G G+P G PG A + G + + AA P Sbjct: 167 AARAGPGP-GPGPGPGPGPGPGKPAG---PGAAQTLNGSAALLNSHHAAAPAVSLVNNGP 222 Query: 67 ARLSALAAAQPRRRSPG-----PQGGGGGDIASPLPPALQPRGAPAVPAA--PSPGPLPA 119 A L L P+ +PG P G +P P+ APA PAA P P P PA Sbjct: 223 AALLPL----PKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA 278 Query: 120 RPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRS------PAPSLRAP 159 + PP P P PTA ++P P Q S PAP+ P Sbjct: 279 TLARPPGHPAGP--PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322 Score = 50.8 bits (120), Expect = 5e-07 Identities = 44/140 (31%), Positives = 51/140 (36%), Gaps = 28/140 (20%) Query: 28 GEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGG 87 G P G GPA G G P P PPA R RP PRR Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEP----PPAGRARPGGGGPQRPGPPSPRRPLVP---- 116 Query: 88 GGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPS---SPPPSPPSPPVPTAQSSL---- 140 A P PPA + R P +A S P+PA + P P+P P P ++L Sbjct: 117 -----AGPAPPAAKLRPPPE-GSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170 Query: 141 -------PAPWPPQGPRSPA 153 P P P GP PA Sbjct: 171 GPGPGPGPGPGPGPGPGKPA 190 Score = 46.6 bits (109), Expect = 9e-06 Identities = 41/110 (37%), Positives = 43/110 (39%), Gaps = 15/110 (13%) Query: 51 APAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPA 110 A +AAH R R +A A S P G G A P PA GAP A Sbjct: 34 AASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAG---AGPAAPA---EGAPG--A 85 Query: 111 APSPGPLP-ARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 AP P P ARP P P PP P P P GP PA LR P Sbjct: 86 APEPPPAGRARPGGGGPQRPGPPSPR------RPLVPAGPAPPAAKLRPP 129 Score = 45.8 bits (107), Expect = 2e-05 Identities = 57/166 (34%), Positives = 61/166 (36%), Gaps = 54/166 (32%) Query: 32 GFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGD 91 G C P PA G PAPA PA PAA A A P PGP G G G Sbjct: 135 GSCAPVPAAAAVAA-GPEPAPAGPAKPAG---PAALA----ARAGP---GPGP-GPGPGP 182 Query: 92 IASPLPPA----------------LQPRGAPAV------PAAPSPGPLPARP-------- 121 P PA APAV PAA P P PA P Sbjct: 183 GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242 Query: 122 ----SSPP----PSPPSPPVPTAQSSLPAPWPPQGPRSPAPSLRAP 159 ++PP PSPP+ P P A PA PP P +PA R P Sbjct: 243 FVGAAAPPAPAAPSPPAAPAPAA----PAAAPPPPPPAPATLARPP 284 Score = 43.1 bits (100), Expect = 1e-04 Identities = 48/159 (30%), Positives = 56/159 (35%), Gaps = 36/159 (22%) Query: 25 VGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAAQPRRRSPGP 84 VG P P P A APAAA PP P AR A P P Sbjct: 244 VGAAAPPAPAAPSPPAAPAPA-----APAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298 Query: 85 ------QGGGGGDIASPLPPALQPRGAPAVP------AAPSPGPLPARP-----SSPPPS 127 GG G +P P A P G P AAP+PG P ++PP + Sbjct: 299 PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAA 358 Query: 128 PP---SPPVPTA---------QSSLPAP--WPPQGPRSP 152 S P TA Q +LP+P PP P +P Sbjct: 359 QTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTP 397 Score = 40.0 bits (92), Expect = 8e-04 Identities = 36/107 (33%), Positives = 40/107 (37%), Gaps = 21/107 (19%) Query: 50 PAPAAAHPPAPRE-RPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP-A 107 P AA PPAP P AA A AA P P P A+ P P G P A Sbjct: 242 PFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAP--------ATLARPPGHPAGPPTA 293 Query: 108 VPAAPSP-----------GPLPARPSSPPPSPPSPPVPTAQSSLPAP 143 PA P P P PA + P P P A ++ PAP Sbjct: 294 APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340 Score = 35.4 bits (80), Expect = 0.021 Identities = 47/156 (30%), Positives = 57/156 (36%), Gaps = 29/156 (18%) Query: 12 AAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGI--RPAP-AAAHPPAP---RERPA 65 AA GG AG P PA G G+ +P P AAA PAP E P Sbjct: 302 AAQNGGSAG-------------AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPK 348 Query: 66 AARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAP-SPGPLPARP--- 121 +A AAQ S GP + P P A P AP +P LP Sbjct: 349 RVVQAAPPAAQTLAAS-GPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGA 407 Query: 122 -----SSPPPSPPSPPVPTAQSSLPAPWPPQGPRSP 152 S P + S T ++ AP PQ P++P Sbjct: 408 VTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443 Score = 33.9 bits (76), Expect = 0.060 Identities = 45/169 (26%), Positives = 58/169 (34%), Gaps = 19/169 (11%) Query: 2 PG-GVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGL------DGIRPAPAA 54 PG G AA V+ R V+ GPA A + G P+PAA Sbjct: 329 PGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAA 388 Query: 55 AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPS- 113 PPAP + +A A Q R+P G I + L P + P P P+ Sbjct: 389 VPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSG---IRATLTPTVLAPRLPQPPQNPTN 445 Query: 114 -------PGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAPS 155 PG + R S P AQ A PQ +P P+ Sbjct: 446 IQNFQLPPGMVLVR-SENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA 493 Score = 26.6 bits (57), Expect = 9.6 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 63 RPAAARLSALAAAQPRRR----SPGPQGGGGGDIASPLPPALQPRGAP 106 R A L+ALAA PR++ PGP G G + P G P Sbjct: 1000 RQRDANLTALAAIGPRKKRKVDCPGPGSGAEGSGPGSVVPGSSGVGTP 1047 >gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] Length = 389 Score = 53.9 bits (128), Expect = 6e-08 Identities = 44/113 (38%), Positives = 47/113 (41%), Gaps = 22/113 (19%) Query: 55 AHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAP---AVPAA 111 A P AP P A A QPR P P + LPP P G P A+P Sbjct: 106 ADPAAPPSSPHAPTRPPPQAVQPRPSEPTPG-------SEALPPGSLPEGEPRPYALPPR 158 Query: 112 PSPGPLPAR---PSSPPPSPPSPPVPTAQSSLPAPWPPQGP--RSPAPSLRAP 159 SP P P R P SP P P PP S PA PP P RSP P +R P Sbjct: 159 ESPAPRPFRWGDPFSPAPPRPQPP------SRPAAQPPSRPAFRSPRP-VRGP 204 Score = 43.9 bits (102), Expect = 6e-05 Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 15/110 (13%) Query: 49 RPAPAAAHPPAPRERPAAARL--SALAAAQPR------RRSPGPQGGGGGDIASPLPPAL 100 RP P A P P + L +L +PR R SP P+ GD SP PP Sbjct: 120 RPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPFRWGDPFSPAPPRP 179 Query: 101 QPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPR 150 QP P+ P+ P P+RP+ P P P P + + Q PR Sbjct: 180 QP------PSRPAAQP-PSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPR 222 Score = 37.7 bits (86), Expect = 0.004 Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 94 SPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPA 153 SP PA P +P P P P + RPS P P + P + P P+ SPA Sbjct: 104 SPADPAAPP-SSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPA 162 Query: 154 P 154 P Sbjct: 163 P 163 >gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] Length = 1126 Score = 53.5 bits (127), Expect = 7e-08 Identities = 50/176 (28%), Positives = 60/176 (34%), Gaps = 29/176 (16%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGVGEPG--GFCLPGPALVVAGLDGIRPAPAAAHPPA 59 PGG + ++G G G + G G L P LV G G+ P PA A A Sbjct: 511 PGGPPVS---GTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567 Query: 60 PRERPAAARLSALAAAQPRRRSPGPQ---------------------GGGGGDIASPLPP 98 A + A P + P PQ G GG +ASP Sbjct: 568 SAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTIT 627 Query: 99 ALQPRGAPAVPAAPSP--GPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSP 152 P G PA + P PPP PP PP P Q+ P P G SP Sbjct: 628 VAMP-GVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSP 682 Score = 40.8 bits (94), Expect = 5e-04 Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 14/144 (9%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPR 61 PGGV +A G G G +G PG P ++ RP P A P P Sbjct: 462 PGGVPSAPTGPL---GPPGHGQTLGQQVPGFPTAPTRVVIA------RPTPPQARPSHPG 512 Query: 62 ERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL-----PPALQPRGAPAVPAAPSPGP 116 P + L + G G + P+ P + P APA +A + Sbjct: 513 GPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTT 572 Query: 117 LPARPSSPPPSPPSPPVPTAQSSL 140 A + P P P+ P PT Q S+ Sbjct: 573 NTATTAGPAPGGPAQPPPTPQPSM 596 Score = 32.3 bits (72), Expect = 0.18 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 19/155 (12%) Query: 11 GAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAAR-- 68 GA+V A V VG F LP V + AP + P R R A+ Sbjct: 121 GASVHDRNANSYVMVGT-----FNLPSDGSAVDVHINMEQAPIQSEP---RVRLVMAQHM 172 Query: 69 ---LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPP 125 + L + R P PQ P PPA+ P P A P P Sbjct: 173 IRDIQTLLSRMECRGGPQPQHSQ----PPPQPPAVTPEPVALSSQTSEPVESEAPPREPM 228 Query: 126 PSPPSPPVPTAQSSLPAPWP-PQGPRSPAPSLRAP 159 + AQ+ P P P GP +PAP AP Sbjct: 229 EAEEVEERAPAQNPELTPGPAPAGP-TPAPETNAP 262 Score = 29.6 bits (65), Expect = 1.1 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 4/81 (4%) Query: 50 PAPAAAHPPA--PRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107 P P + PP P P LS+ + +P P+ + PA P P Sbjct: 189 PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAP-PREPMEAEEVEERAPAQNPELTPG 247 Query: 108 -VPAAPSPGPLPARPSSPPPS 127 PA P+P P P+ P P+ Sbjct: 248 PAPAGPTPAPETNAPNHPSPA 268 Score = 28.5 bits (62), Expect = 2.5 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 106 PAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 P P A +P P P + SS PS S V ++ P P P P + P Sbjct: 389 PPTPNAEAPPPGPGQASSVAPS--STNVESSAEGAPPPGPAPPPATSHP 435 Score = 27.3 bits (59), Expect = 5.6 Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Query: 88 GGGDIASPLPPALQPRGAP--AVPAAPSPGPLPARPSSPPPSPPSPPVPTA 136 G G P P A P P A APS + + PP P+PP T+ Sbjct: 383 GNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATS 433 >gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] Length = 1126 Score = 53.5 bits (127), Expect = 7e-08 Identities = 50/176 (28%), Positives = 60/176 (34%), Gaps = 29/176 (16%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGVGEPG--GFCLPGPALVVAGLDGIRPAPAAAHPPA 59 PGG + ++G G G + G G L P LV G G+ P PA A A Sbjct: 511 PGGPPVS---GTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567 Query: 60 PRERPAAARLSALAAAQPRRRSPGPQ---------------------GGGGGDIASPLPP 98 A + A P + P PQ G GG +ASP Sbjct: 568 SAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTIT 627 Query: 99 ALQPRGAPAVPAAPSP--GPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSP 152 P G PA + P PPP PP PP P Q+ P P G SP Sbjct: 628 VAMP-GVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSP 682 Score = 40.8 bits (94), Expect = 5e-04 Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 14/144 (9%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPR 61 PGGV +A G G G +G PG P ++ RP P A P P Sbjct: 462 PGGVPSAPTGPL---GPPGHGQTLGQQVPGFPTAPTRVVIA------RPTPPQARPSHPG 512 Query: 62 ERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL-----PPALQPRGAPAVPAAPSPGP 116 P + L + G G + P+ P + P APA +A + Sbjct: 513 GPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTT 572 Query: 117 LPARPSSPPPSPPSPPVPTAQSSL 140 A + P P P+ P PT Q S+ Sbjct: 573 NTATTAGPAPGGPAQPPPTPQPSM 596 Score = 32.3 bits (72), Expect = 0.18 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 19/155 (12%) Query: 11 GAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAAR-- 68 GA+V A V VG F LP V + AP + P R R A+ Sbjct: 121 GASVHDRNANSYVMVGT-----FNLPSDGSAVDVHINMEQAPIQSEP---RVRLVMAQHM 172 Query: 69 ---LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPP 125 + L + R P PQ P PPA+ P P A P P Sbjct: 173 IRDIQTLLSRMECRGGPQPQHSQ----PPPQPPAVTPEPVALSSQTSEPVESEAPPREPM 228 Query: 126 PSPPSPPVPTAQSSLPAPWP-PQGPRSPAPSLRAP 159 + AQ+ P P P GP +PAP AP Sbjct: 229 EAEEVEERAPAQNPELTPGPAPAGP-TPAPETNAP 262 Score = 29.6 bits (65), Expect = 1.1 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 4/81 (4%) Query: 50 PAPAAAHPPA--PRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107 P P + PP P P LS+ + +P P+ + PA P P Sbjct: 189 PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAP-PREPMEAEEVEERAPAQNPELTPG 247 Query: 108 -VPAAPSPGPLPARPSSPPPS 127 PA P+P P P+ P P+ Sbjct: 248 PAPAGPTPAPETNAPNHPSPA 268 Score = 28.5 bits (62), Expect = 2.5 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 106 PAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 P P A +P P P + SS PS S V ++ P P P P + P Sbjct: 389 PPTPNAEAPPPGPGQASSVAPS--STNVESSAEGAPPPGPAPPPATSHP 435 Score = 27.3 bits (59), Expect = 5.6 Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Query: 88 GGGDIASPLPPALQPRGAP--AVPAAPSPGPLPARPSSPPPSPPSPPVPTA 136 G G P P A P P A APS + + PP P+PP T+ Sbjct: 383 GNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATS 433 >gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] Length = 1126 Score = 53.5 bits (127), Expect = 7e-08 Identities = 50/176 (28%), Positives = 60/176 (34%), Gaps = 29/176 (16%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGVGEPG--GFCLPGPALVVAGLDGIRPAPAAAHPPA 59 PGG + ++G G G + G G L P LV G G+ P PA A A Sbjct: 511 PGGPPVS---GTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567 Query: 60 PRERPAAARLSALAAAQPRRRSPGPQ---------------------GGGGGDIASPLPP 98 A + A P + P PQ G GG +ASP Sbjct: 568 SAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTIT 627 Query: 99 ALQPRGAPAVPAAPSP--GPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSP 152 P G PA + P PPP PP PP P Q+ P P G SP Sbjct: 628 VAMP-GVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSP 682 Score = 40.8 bits (94), Expect = 5e-04 Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 14/144 (9%) Query: 2 PGGVQAARFGAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPR 61 PGGV +A G G G +G PG P ++ RP P A P P Sbjct: 462 PGGVPSAPTGPL---GPPGHGQTLGQQVPGFPTAPTRVVIA------RPTPPQARPSHPG 512 Query: 62 ERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPL-----PPALQPRGAPAVPAAPSPGP 116 P + L + G G + P+ P + P APA +A + Sbjct: 513 GPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTT 572 Query: 117 LPARPSSPPPSPPSPPVPTAQSSL 140 A + P P P+ P PT Q S+ Sbjct: 573 NTATTAGPAPGGPAQPPPTPQPSM 596 Score = 32.3 bits (72), Expect = 0.18 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 19/155 (12%) Query: 11 GAAVRGGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAAR-- 68 GA+V A V VG F LP V + AP + P R R A+ Sbjct: 121 GASVHDRNANSYVMVGT-----FNLPSDGSAVDVHINMEQAPIQSEP---RVRLVMAQHM 172 Query: 69 ---LSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPP 125 + L + R P PQ P PPA+ P P A P P Sbjct: 173 IRDIQTLLSRMECRGGPQPQHSQ----PPPQPPAVTPEPVALSSQTSEPVESEAPPREPM 228 Query: 126 PSPPSPPVPTAQSSLPAPWP-PQGPRSPAPSLRAP 159 + AQ+ P P P GP +PAP AP Sbjct: 229 EAEEVEERAPAQNPELTPGPAPAGP-TPAPETNAP 262 Score = 29.6 bits (65), Expect = 1.1 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 4/81 (4%) Query: 50 PAPAAAHPPA--PRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107 P P + PP P P LS+ + +P P+ + PA P P Sbjct: 189 PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAP-PREPMEAEEVEERAPAQNPELTPG 247 Query: 108 -VPAAPSPGPLPARPSSPPPS 127 PA P+P P P+ P P+ Sbjct: 248 PAPAGPTPAPETNAPNHPSPA 268 Score = 28.5 bits (62), Expect = 2.5 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 106 PAVPAAPSPGPLPARPSSPPPSPPSPPVPTAQSSLPAPWPPQGPRSPAP 154 P P A +P P P + SS PS S V ++ P P P P + P Sbjct: 389 PPTPNAEAPPPGPGQASSVAPS--STNVESSAEGAPPPGPAPPPATSHP 435 Score = 27.3 bits (59), Expect = 5.6 Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Query: 88 GGGDIASPLPPALQPRGAP--AVPAAPSPGPLPARPSSPPPSPPSPPVPTA 136 G G P P A P P A APS + + PP P+PP T+ Sbjct: 383 GNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATS 433 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.137 0.442 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,235,110 Number of Sequences: 37866 Number of extensions: 1056606 Number of successful extensions: 47350 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 2207 Number of HSP's successfully gapped in prelim test: 2160 Number of HSP's that attempted gapping in prelim test: 8645 Number of HSP's gapped (non-prelim): 19180 length of query: 159 length of database: 18,247,518 effective HSP length: 94 effective length of query: 65 effective length of database: 14,688,114 effective search space: 954727410 effective search space used: 954727410 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.