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Search of human proteins with 118918435
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118918435 von Willebrand factor A domain containing 3B [Homo
sapiens]
(1294 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118918435 von Willebrand factor A domain containing 3B [Homo ... 2593 0.0
gi|218505703 von Willebrand factor A domain containing 3A [Homo ... 177 8e-44
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [... 54 7e-07
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens] 48 5e-05
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens] 45 4e-04
gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ... 43 0.002
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor... 43 0.002
gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor... 43 0.002
gi|221316754 exophilin 5 isoform c [Homo sapiens] 37 0.12
gi|221316751 exophilin 5 isoform b [Homo sapiens] 37 0.12
gi|221316747 exophilin 5 isoform a [Homo sapiens] 37 0.12
gi|88759348 ring finger protein 219 [Homo sapiens] 37 0.12
gi|21264355 SWI/SNF-related matrix-associated actin-dependent re... 35 0.36
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 35 0.61
gi|154354979 myosin X [Homo sapiens] 34 0.79
gi|218505694 potassium channel tetramerisation domain containing... 34 0.79
gi|22749217 coiled-coil domain containing 63 [Homo sapiens] 33 1.4
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 33 1.8
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 33 1.8
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 33 1.8
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 33 2.3
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 33 2.3
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 33 2.3
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 33 2.3
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 33 2.3
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 33 2.3
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 33 2.3
gi|116875848 KIAA1946 [Homo sapiens] 33 2.3
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 33 2.3
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 33 2.3
>gi|118918435 von Willebrand factor A domain containing 3B [Homo
sapiens]
Length = 1294
Score = 2593 bits (6722), Expect = 0.0
Identities = 1294/1294 (100%), Positives = 1294/1294 (100%)
Query: 1 MEKSGPSSTISEQQLQRQEGWINTKTDLAEQSLISSEKWLQLHGLKSNKLTLKQILSQIG 60
MEKSGPSSTISEQQLQRQEGWINTKTDLAEQSLISSEKWLQLHGLKSNKLTLKQILSQIG
Sbjct: 1 MEKSGPSSTISEQQLQRQEGWINTKTDLAEQSLISSEKWLQLHGLKSNKLTLKQILSQIG 60
Query: 61 FPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYK 120
FPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYK
Sbjct: 61 FPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYK 120
Query: 121 QRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNII 180
QRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNII
Sbjct: 121 QRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNII 180
Query: 181 RVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYY 240
RVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYY
Sbjct: 181 RVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYY 240
Query: 241 FVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTE 300
FVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTE
Sbjct: 241 FVVGDVPEESKELLLQRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTE 300
Query: 301 CVEFPAFSTKDGDNVMTWNSRKLKGKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAE 360
CVEFPAFSTKDGDNVMTWNSRKLKGKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAE
Sbjct: 301 CVEFPAFSTKDGDNVMTWNSRKLKGKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAE 360
Query: 361 PPKPDVATVDCESETTSVEIASNPEDTWDSKTWLQKYGLKAQKLSLYDVLADCSFRHADG 420
PPKPDVATVDCESETTSVEIASNPEDTWDSKTWLQKYGLKAQKLSLYDVLADCSFRHADG
Sbjct: 361 PPKPDVATVDCESETTSVEIASNPEDTWDSKTWLQKYGLKAQKLSLYDVLADCSFRHADG 420
Query: 421 VVDIKAKPENESVQTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIH 480
VVDIKAKPENESVQTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIH
Sbjct: 421 VVDIKAKPENESVQTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIH 480
Query: 481 TALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKY 540
TALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKY
Sbjct: 481 TALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKY 540
Query: 541 KSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQ 600
KSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQ
Sbjct: 541 KSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQ 600
Query: 601 AIYLLTDGRPDQPPETVIDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYN 660
AIYLLTDGRPDQPPETVIDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYN
Sbjct: 601 AIYLLTDGRPDQPPETVIDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYN 660
Query: 661 FGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQK 720
FGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQK
Sbjct: 661 FGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQK 720
Query: 721 EICSMISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRSQ 780
EICSMISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRSQ
Sbjct: 721 EICSMISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRSQ 780
Query: 781 MSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEKVTREGSQVYDHDS 840
MSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEKVTREGSQVYDHDS
Sbjct: 781 MSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEKVTREGSQVYDHDS 840
Query: 841 SDVSSENWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCN 900
SDVSSENWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCN
Sbjct: 841 SDVSSENWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCN 900
Query: 901 DTNKMTLINPQGAKLNIYKRKVEQAIQSYEKRLNKIVWRALSQEEKEKLDANKPIQYLEN 960
DTNKMTLINPQGAKLNIYKRKVEQAIQSYEKRLNKIVWRALSQEEKEKLDANKPIQYLEN
Sbjct: 901 DTNKMTLINPQGAKLNIYKRKVEQAIQSYEKRLNKIVWRALSQEEKEKLDANKPIQYLEN 960
Query: 961 KTVLNQALERLNWPISLKELSMLESEILAGKMYIQQAMELQEAAKKNYANKAPGEQQKLQ 1020
KTVLNQALERLNWPISLKELSMLESEILAGKMYIQQAMELQEAAKKNYANKAPGEQQKLQ
Sbjct: 961 KTVLNQALERLNWPISLKELSMLESEILAGKMYIQQAMELQEAAKKNYANKAPGEQQKLQ 1020
Query: 1021 GNPTKKTKSKRPDPLKGQKVIARCDENGFYFPGVVKKCVSRTQALVGFSYGDTKVVSTSF 1080
GNPTKKTKSKRPDPLKGQKVIARCDENGFYFPGVVKKCVSRTQALVGFSYGDTKVVSTSF
Sbjct: 1021 GNPTKKTKSKRPDPLKGQKVIARCDENGFYFPGVVKKCVSRTQALVGFSYGDTKVVSTSF 1080
Query: 1081 ITPVGGAMPCPLLQVGDYVFAKIVIPKGFDFYVPAIVIALPNKHVATEKFYTVLKCNNRR 1140
ITPVGGAMPCPLLQVGDYVFAKIVIPKGFDFYVPAIVIALPNKHVATEKFYTVLKCNNRR
Sbjct: 1081 ITPVGGAMPCPLLQVGDYVFAKIVIPKGFDFYVPAIVIALPNKHVATEKFYTVLKCNNRR 1140
Query: 1141 EFCPRSALIKISQNKYALSCSHIKSPPIPEDPEVEDVEARNSAFLFWPLKEADTQDSREP 1200
EFCPRSALIKISQNKYALSCSHIKSPPIPEDPEVEDVEARNSAFLFWPLKEADTQDSREP
Sbjct: 1141 EFCPRSALIKISQNKYALSCSHIKSPPIPEDPEVEDVEARNSAFLFWPLKEADTQDSREP 1200
Query: 1201 RREKPRRKKRPAKQPLQQAAPSDSDGSSHGISSHGSCQGTHPEPRTAHLHFPAAGRLGLS 1260
RREKPRRKKRPAKQPLQQAAPSDSDGSSHGISSHGSCQGTHPEPRTAHLHFPAAGRLGLS
Sbjct: 1201 RREKPRRKKRPAKQPLQQAAPSDSDGSSHGISSHGSCQGTHPEPRTAHLHFPAAGRLGLS 1260
Query: 1261 SHAIIATPPPRAALPCTLQATHSSKGLRSVPETL 1294
SHAIIATPPPRAALPCTLQATHSSKGLRSVPETL
Sbjct: 1261 SHAIIATPPPRAALPCTLQATHSSKGLRSVPETL 1294
>gi|218505703 von Willebrand factor A domain containing 3A [Homo
sapiens]
Length = 1184
Score = 177 bits (448), Expect = 8e-44
Identities = 223/986 (22%), Positives = 392/986 (39%), Gaps = 181/986 (18%)
Query: 13 QQLQRQEGWINTKTDLAEQSLISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLG 72
Q L R +G +D + SE WL H LK KLTL ++SQ G
Sbjct: 72 QDLLRLQGSETQSSDWED-----SEDWLSAHSLKCQKLTLADLISQ-------------G 113
Query: 73 RPVASRYADGLFPQLYRAEDGR--VYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKS 130
V E+G V + +++I F L+ +E Y++R+ WLT S
Sbjct: 114 TEVL--------------EEGTNVVQKICFSTQIIRHFESKLSDTIEVYQERIQWLTENS 159
Query: 131 RQIFGVILEQCVTIVLDFGGILEG-ELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKW 189
++ FG+I V+I++D I G + + ++ L ++ EQ++H + ++
Sbjct: 160 KKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSL 219
Query: 190 QENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEE 249
+ V+ ++ WV+ L + + L AL + K ++S+ ++ P++
Sbjct: 220 WPDPMEVSASTLQELKLWVKTLQPD---GGSNLLQALKKIFTLKGLDSLVA-IMRSCPDQ 275
Query: 250 SKELLL----QRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTECVEFP 305
E+L Q + ++ +++ + A LK+L+ +H ++ + E
Sbjct: 276 PSEILSDYIQQSTMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYHCYSPKME----- 330
Query: 306 AFSTKDGDNVMTWNSRKLKGKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAEPPKPD 365
++++D D ++ E+++A S L+ +Q L P
Sbjct: 331 HYTSRDMDELLA-------------------------EIQKAQSLLSHVQALQHSSP--- 362
Query: 366 VATVDCESETTSVEIASNPEDTW--------------------DSKTWLQKYGLKAQKLS 405
+ C E S EI + P + S WL+ GLKA+KLS
Sbjct: 363 CEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLDKTSAEWLKVNGLKAKKLS 422
Query: 406 LYDVLADCSFRHADGVVDIKAKPENESVQTSAETNKKTVHAKYCSRFVHAPWKDGSLVHV 465
LY VLA +F P E V +T T+H K +F W DG++ ++
Sbjct: 423 LYQVLAPNAF-----------SPVEEFVPILQKTVSSTIHEKAMIQF---EWHDGTVKNI 468
Query: 466 NITKEKCKWYSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDL 525
++ Y +++ A+ RRI+WL S+ ++G + + +L+D S + +
Sbjct: 469 HVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIH 528
Query: 526 VKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTN 585
++ + ++EQL K FN + F +WR ++ V+ +NL+ A W +++ S N
Sbjct: 529 IQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRN 588
Query: 586 TLSALKTA----FADK---ETQAIYLLTDGRPDQPPETV--------------------- 617
LSAL+ A F DK ++Q IYL T G PDQ T+
Sbjct: 589 VLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFY 648
Query: 618 IDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYNFGCKDPTPPEAVQNEDL 677
+ + K P S + D A KEV GG FH++ +++D+
Sbjct: 649 VGEPKMDTTPPARYAS--HTDTAA--AYKEVTRAAGGRFHWFG-------DTGIYESDDI 697
Query: 678 TLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQS 737
++ EME+ + +K L + SL K + + + S P+K P+
Sbjct: 698 NSIMSEMEKALNYSQKCAFLMA-SLKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRP 756
Query: 738 DVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRSQMSSLRSSACSERKDGLS 797
V S+ D +K L +S K L S++ + +A K+G+
Sbjct: 757 TVPLGARMSIK--------DDPDREKSPPL--KSLKWRPLSSRV-GISPAAAQPTKEGMM 805
Query: 798 NASSRRTALSDKEMSILL--AEEWLDDKSSEKVTREG------SQVYDHDSSDV--SSEN 847
R+T + E S+LL E+ D S K +G S D D SS+
Sbjct: 806 EL-RRKTKSREAETSLLLFYTEKGNDVGSVYKKYPQGRGLRRTSSSIDLPRKDTVCSSQE 864
Query: 848 WLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCNDTNKMTL 907
W+ YGL KL + + S KH +FP + +
Sbjct: 865 WVAKYGLKKLKLEISRCMGPNCTHQKSGQRSASAKHC------SIFPSVEI---HGVVRH 915
Query: 908 INPQGAKLNIYKRKVEQAIQSYEKRL 933
I ++ +Y R +E+ ++ Y +RL
Sbjct: 916 IQWTPREMEVYIRHLEKVLRRYVQRL 941
Score = 143 bits (361), Expect = 9e-34
Identities = 104/349 (29%), Positives = 169/349 (48%), Gaps = 49/349 (14%)
Query: 376 TSVEIASNPEDT-WDSKTWLQKYGLKAQKLSLYDVLA-DCSFRHADGVVDIKAKPENESV 433
TS I +DT S+ W+ KYGLK KL + + +C
Sbjct: 847 TSSSIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCMGPNC-------------------- 886
Query: 434 QTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIHTALARIRRRIKWL 493
T ++ +++ AK+CS F G + H+ T + + Y + L R +R++WL
Sbjct: 887 -THQKSGQRSASAKHCSIFPSVEIH-GVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWL 944
Query: 494 QDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQL-KYKSKFNFVKFDGQ 552
GS+ LFG + + IL+DTS SM L VK +++ I EQL K FN + F
Sbjct: 945 LSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAES 1004
Query: 553 AVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQAIYLLTDGRPDQ 612
+W++ L E + +A W+ ++ ST+ L AL AF+ + + +YLLTDG+PD
Sbjct: 1005 FQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDT 1064
Query: 613 PPETVIDQVKRFQE---IPIYTISFNYNDEIANRFLKEVAALTGGEFH------------ 657
V+++V++ +E + ++TIS N +D A FL+++A+ TGG +H
Sbjct: 1065 SCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIH 1124
Query: 658 ------FYNFGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSE 700
F N KDPT P + +DL +L +E+ + S L + Q S+
Sbjct: 1125 SLLTKGFINE--KDPTLP-PFEGDDLRILAQEITKARSFLWQAQSFRSQ 1170
Score = 104 bits (259), Expect = 6e-22
Identities = 90/343 (26%), Positives = 158/343 (46%), Gaps = 26/343 (7%)
Query: 30 EQSLISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYR 89
+ ++ SS++W+ +GLK KL + + + P+C + G+ AS +FP +
Sbjct: 856 KDTVCSSQEWVAKYGLKKLKLEISRCMG----PNCTHQKS--GQRSASAKHCSIFPSVEI 909
Query: 90 AEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFG 149
R T + +Y + HL + + Y QR+ WL S SR++FG +LE V I+LD
Sbjct: 910 HGVVRHIQWTPREMEVY--IRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTS 967
Query: 150 GILEGELDLCREALTMVLQEQVAHITE-FNIIRVSQEPVKWQENATPVTEQSIATAISWV 208
G + L + L +++ EQ+ + FN++ ++ WQ+ T+ + A+ WV
Sbjct: 968 GSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWV 1027
Query: 209 EKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEI----PCP 264
L + + S L ALL+A +E +Y G P+ S L+L ++
Sbjct: 1028 THLQAQGSTS---ILQALLKAFSFHDLEGLYLLTDGK-PDTSCSLVLNEVQKLREKRDVK 1083
Query: 265 VYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTECVEFPAFSTKDGDNVMTWNSRKLK 324
V+T+S N + FL+ L++ T R+H + + TK N +
Sbjct: 1084 VHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFIN-------EKD 1136
Query: 325 GKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAEPPKPDVA 367
LPP G +D+ ++ QE+ +A S L Q Q ++ K + A
Sbjct: 1137 PTLPPFEG--DDLRILAQEITKARSFLWQAQSFRSQLQKKNDA 1177
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/101 (31%), Positives = 53/101 (52%), Gaps = 5/101 (4%)
Query: 842 DVSSENWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCND 901
D +S WLK GL AKKL+L L+ A +VP+L K V S + ++ +
Sbjct: 404 DKTSAEWLKVNGLKAKKLSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDG 463
Query: 902 TNKMTLINPQGAKLNIYKRKVEQAIQSYEKRLNKIVWRALS 942
T K ++P L Y++++ +A++ YE+R I W +L+
Sbjct: 464 TVKNIHVDP--PFLYKYQQQLSRAMRMYERR---IEWLSLA 499
>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
[Homo sapiens]
Length = 890
Score = 54.3 bits (129), Expect = 7e-07
Identities = 40/161 (24%), Positives = 79/161 (49%), Gaps = 25/161 (15%)
Query: 509 IYILIDTSHSMKS-KLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDN 567
+ +ID S SM KL+ K+ +++ + E ++ + NF+ F G W+E L + +N
Sbjct: 285 VAFVIDISGSMAGRKLEQTKEALLRIL-EDMQEEDYLNFILFSGDVSTWKEHLVQATPEN 343
Query: 568 LEQAQSWIRDIKIGSSTNT-------LSALKTA-----FADKETQAIYLLTDG------- 608
L++A+++++ ++ TN +S L A ++ T + +LTDG
Sbjct: 344 LQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVGES 403
Query: 609 RPDQPPETVIDQVKRFQEIPIYTISFNYNDEIANRFLKEVA 649
RP++ E V + + + P+Y + F N + FL+ +A
Sbjct: 404 RPEKIQENVRNAIG--GKFPLYNLGFGNN--LNYNFLENMA 440
>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
Length = 930
Score = 48.1 bits (113), Expect = 5e-05
Identities = 37/162 (22%), Positives = 71/162 (43%), Gaps = 17/162 (10%)
Query: 509 IYILIDTSHSMKS-KLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDN 567
+ +ID S SM K+ ++ +I+ + + L + +FN + F +A WR L + +N
Sbjct: 275 VVFVIDKSGSMSGRKIQQTREALIKILDD-LSPRDQFNLIVFSTEATQWRPSLVPASAEN 333
Query: 568 LEQAQSWIRDIKIGSSTNTLSALKTA------------FADKETQAIYLLTDGRP---DQ 612
+ +A+S+ I+ TN A+ A + I LLTDG P +
Sbjct: 334 VNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVGET 393
Query: 613 PPETVIDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTGG 654
P ++ + V+ + +++ FL+++A GG
Sbjct: 394 NPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGG 435
Score = 32.7 bits (73), Expect = 2.3
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 142 VTIVLDFGGILEG-ELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQS 200
V V+D G + G ++ REAL +L + ++ +FN+I S E +W+ + P + ++
Sbjct: 275 VVFVIDKSGSMSGRKIQQTREALIKILDD-LSPRDQFNLIVFSTEATQWRPSLVPASAEN 333
Query: 201 IATAISW 207
+ A S+
Sbjct: 334 VNKARSF 340
>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
Length = 911
Score = 45.1 bits (105), Expect = 4e-04
Identities = 35/153 (22%), Positives = 72/153 (47%), Gaps = 25/153 (16%)
Query: 506 NDCIYILIDTSHSMKS-KLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVN 564
N + +ID S SM+ K+ K+ +++ + + ++ F+ V F + +W+ L + +
Sbjct: 290 NKNVVFVIDISGSMRGQKVKQTKEALLKILGD-MQPGDYFDLVLFGTRVQSWKGSLVQAS 348
Query: 565 EDNLEQAQSWIRDIKIGSSTN----------TLSALKTAFADKETQA--IYLLTDGRPDQ 612
E NL+ AQ ++R + +TN L+ ++ + + A + +LTDG
Sbjct: 349 EANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDG---D 405
Query: 613 PPETVIDQVKRFQEI--------PIYTISFNYN 637
P E V D+ + + + P+Y + F +N
Sbjct: 406 PTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHN 438
>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 3 [Homo sapiens]
Length = 702
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 13/119 (10%)
Query: 504 LHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEV 563
L + +++L ++ + +KL KD + + + L+ + +F+ + F + W++ L V
Sbjct: 292 LPKNVVFVLDSSASMVGTKLRQTKDALFTILHD-LRPQDRFSIIGFSNRIKVWKDHLISV 350
Query: 564 NEDNLEQAQSWIRDIKIGSSTNTLSALKTAF------------ADKETQAIYLLTDGRP 610
D++ + +I + T+ AL+ A D+ I LTDG+P
Sbjct: 351 TPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 409
>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 1 [Homo sapiens]
Length = 956
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 13/119 (10%)
Query: 504 LHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEV 563
L + +++L ++ + +KL KD + + + L+ + +F+ + F + W++ L V
Sbjct: 292 LPKNVVFVLDSSASMVGTKLRQTKDALFTILHD-LRPQDRFSIIGFSNRIKVWKDHLISV 350
Query: 564 NEDNLEQAQSWIRDIKIGSSTNTLSALKTAF------------ADKETQAIYLLTDGRP 610
D++ + +I + T+ AL+ A D+ I LTDG+P
Sbjct: 351 TPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 409
>gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 2 [Homo sapiens]
Length = 742
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 13/119 (10%)
Query: 504 LHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEV 563
L + +++L ++ + +KL KD + + + L+ + +F+ + F + W++ L V
Sbjct: 78 LPKNVVFVLDSSASMVGTKLRQTKDALFTILHD-LRPQDRFSIIGFSNRIKVWKDHLISV 136
Query: 564 NEDNLEQAQSWIRDIKIGSSTNTLSALKTAF------------ADKETQAIYLLTDGRP 610
D++ + +I + T+ AL+ A D+ I LTDG+P
Sbjct: 137 TPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 195
>gi|221316754 exophilin 5 isoform c [Homo sapiens]
Length = 1801
Score = 37.0 bits (84), Expect = 0.12
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Query: 725 MISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLL--RSQMS 782
M S + P+ + + + S N+ K P G S+ K ++ K L +E+ TSL+ R +S
Sbjct: 1159 MASVEAAVSLPEEESKAREIFSDNLAKTPLGDSENKKERGKKLQSETLHTSLMLQRKNVS 1218
Query: 783 SLRSSACSERKDGLSNASSRRTALSD 808
+S C + + ++ S ALS+
Sbjct: 1219 EEKSENCQQSINSSNSGPSSLPALSE 1244
>gi|221316751 exophilin 5 isoform b [Homo sapiens]
Length = 1913
Score = 37.0 bits (84), Expect = 0.12
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Query: 725 MISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLL--RSQMS 782
M S + P+ + + + S N+ K P G S+ K ++ K L +E+ TSL+ R +S
Sbjct: 1271 MASVEAAVSLPEEESKAREIFSDNLAKTPLGDSENKKERGKKLQSETLHTSLMLQRKNVS 1330
Query: 783 SLRSSACSERKDGLSNASSRRTALSD 808
+S C + + ++ S ALS+
Sbjct: 1331 EEKSENCQQSINSSNSGPSSLPALSE 1356
>gi|221316747 exophilin 5 isoform a [Homo sapiens]
Length = 1989
Score = 37.0 bits (84), Expect = 0.12
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Query: 725 MISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLL--RSQMS 782
M S + P+ + + + S N+ K P G S+ K ++ K L +E+ TSL+ R +S
Sbjct: 1347 MASVEAAVSLPEEESKAREIFSDNLAKTPLGDSENKKERGKKLQSETLHTSLMLQRKNVS 1406
Query: 783 SLRSSACSERKDGLSNASSRRTALSD 808
+S C + + ++ S ALS+
Sbjct: 1407 EEKSENCQQSINSSNSGPSSLPALSE 1432
>gi|88759348 ring finger protein 219 [Homo sapiens]
Length = 726
Score = 37.0 bits (84), Expect = 0.12
Identities = 63/298 (21%), Positives = 111/298 (37%), Gaps = 23/298 (7%)
Query: 558 EQLAEVNEDNLEQAQSWIRDIK-----IGSSTNTLSALKTAFADKETQAIYLLTDGRPDQ 612
E L + ED ++ Q + ++K + S T+ T + + +L+TD
Sbjct: 93 ELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKI 152
Query: 613 PPETVIDQVKRFQEI-PIYTISFNYNDEI--ANRFLKEVAALTGGEFHFYNFGCK---DP 666
PETV + K+ + IY + D++ AN+ LK L G N K D
Sbjct: 153 NPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLK----LENGGLVRENLRLKAEVDN 208
Query: 667 TPPEAVQNEDLTLLVKEMEQGHSDLEKMQ------DLYSESLIMDWWYNAEKDGDSKHQK 720
P+ + L ++EQ + +++ D Y E L + +
Sbjct: 209 RSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMN 268
Query: 721 EIC-SMISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRS 779
IC + +S K +K + ++ + K P + K + TS R
Sbjct: 269 SICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQ 328
Query: 780 QMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEKVTREGSQVYD 837
+ +S CS+ KD ++D M L EW +K S+ V + ++YD
Sbjct: 329 ESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREW-GNKPSDCVPYKDEELYD 385
>gi|21264355 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin e1 [Homo sapiens]
Length = 411
Score = 35.4 bits (80), Expect = 0.36
Identities = 37/170 (21%), Positives = 76/170 (44%), Gaps = 23/170 (13%)
Query: 869 AVPHSSTYVPVLDKHVVSKVFDE-VFPLAHVCNDTNKMTLINPQGAKLNIYKRKVEQAIQ 927
++ H++T + ++S++ E V P T +M ++ Q L +++RK+E +
Sbjct: 187 SMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELL 246
Query: 928 SYEKRLNKIVWRALSQEEKEKLDANKPIQYLENKTVLNQALER---LNWPISLKELS--M 982
E+R QE+K K +LE+ N L+R L + +++++ +
Sbjct: 247 QIEER---------HQEKKRK--------FLESTDSFNNELKRLCGLKVEVDMEKIAAEI 289
Query: 983 LESEILAGKMYIQQAMELQEAAKKNYANKAPGEQQKLQGNPTKKTKSKRP 1032
++E A K ++ E E A+++ ++ P E+Q KK P
Sbjct: 290 AQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIP 339
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 34.7 bits (78), Expect = 0.61
Identities = 52/230 (22%), Positives = 86/230 (37%), Gaps = 21/230 (9%)
Query: 602 IYLLTDGRPDQPPETVIDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTG--GEFHFY 659
IY+ D E ++ K + Y I Y D I EVA L+ E
Sbjct: 215 IYVEEDLAQQDKDEIILLLGKEVSRLSDYEIESKYKDVIIANLQNEVAELSQKVSETTTS 274
Query: 660 NFGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQ 719
K+ + V +ED+ KE++ S + +Q YS+ L S+
Sbjct: 275 RQNEKEISQKCQVLDEDIDAKQKEIQSLKSQISALQKGYSKVLCQTL---------SERN 325
Query: 720 KEICSMISTPEKCAKPQSDVDSTQTSSL-NMLKGPWGLSDQKVQ--KKKVLHAESTKTSL 776
EI S+ + E + D+ TS + + L+ D++VQ K++V H +S
Sbjct: 326 SEITSLKNEGENLKR-----DNAITSGMVSSLQKDILAKDEQVQQLKEEVSHLKSQNKD- 379
Query: 777 LRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSE 826
+ S CS K+ L + R +E + L + + D E
Sbjct: 380 -KDHQLEALGSRCSVLKEELKQEDAHRELREAQEKELKLCKTQIQDMEKE 428
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 34.3 bits (77), Expect = 0.79
Identities = 26/103 (25%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
Query: 919 KRKVEQAIQSYEKRLNKIVWRALSQEEKEKLDANKPIQYLENKTVLNQALERLNWPISLK 978
K+K E+ + E+ + RA +EE K + +Q + + L + LE+ ++
Sbjct: 829 KKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVE 888
Query: 979 ELSMLESEIL-AGKMYIQQAMELQEAAKKNYANKAPGEQQKLQ 1020
E+ LE EI +M QQ + L EA+ + + E ++L+
Sbjct: 889 EILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLE 931
>gi|218505694 potassium channel tetramerisation domain containing 1
isoform b [Homo sapiens]
Length = 865
Score = 34.3 bits (77), Expect = 0.79
Identities = 31/117 (26%), Positives = 46/117 (39%), Gaps = 12/117 (10%)
Query: 1144 PRSALIKISQNKYALSCSHIKSPPIPEDPEVEDVEARNSAFLFWPLKEADTQDSREPRRE 1203
P+ I+ S+ A+ +K P+P PE + NS + P + TQDSR P
Sbjct: 552 PKRLCIRPSEPVDAVVVVSVKHDPLPLLPEANGHRSTNSPTIVSPAIVSPTQDSR-PNMS 610
Query: 1204 KPRRKKRPAK-----------QPLQQAAPSDSDGSSHGISSHGSCQGTHPEPRTAHL 1249
+P + PA Q + AP D H +S + +PE R L
Sbjct: 611 RPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRL 667
>gi|22749217 coiled-coil domain containing 63 [Homo sapiens]
Length = 563
Score = 33.5 bits (75), Expect = 1.4
Identities = 63/268 (23%), Positives = 105/268 (39%), Gaps = 45/268 (16%)
Query: 765 KVLHAESTKTSLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKE--------MSILLA 816
K L E + +LL S M S R+ SE+ N R L KE + +LLA
Sbjct: 64 KTLKTEQDEITLLLSLMKSSRNMNRSEK-----NYMELRLLLQTKEDYEALIKSLKVLLA 118
Query: 817 EEWLDDK--SSEKVTREGSQVYDHDSSDVSSENWLKTYGLVAKKLTLMDA-LSVAAVPHS 873
E LD+K EK Q++ + K ++ +L L+ ++
Sbjct: 119 E--LDEKILQMEKKIANQKQIFAKMQEANNPRKLQKQIHILETRLNLVTVHFDKMLTTNA 176
Query: 874 STYVPVLDKHVVSKVFDEVFPLAHVCNDTNKMTLINPQGAKLNIYKRKVEQAIQSYEKRL 933
+ D +D V+ C K T+ +EQ+ Q+YE+R+
Sbjct: 177 KLRKEIEDLRFEKAAYDNVYQQLQHCLLMEKKTM-----------NLAIEQSSQAYEQRV 225
Query: 934 NKIVWRALSQEEKEKLDANKPIQYLENKTVLNQALERLNWPISLKELSMLESEILAGKMY 993
+ R + ++++K D + QY + + LERL S L+S +L +
Sbjct: 226 EAMA-RMAAMKDRQKKDTS---QY----NLEIRELERL-----YAHESKLKSFLL---VK 269
Query: 994 IQQAMELQEAAKKNYANKAPGEQQKLQG 1021
+ E +E AK+ A KA +K +G
Sbjct: 270 LNDRNEFEEQAKREEALKAKKHVKKNRG 297
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 33.1 bits (74), Expect = 1.8
Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 677 LTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQ 736
+ +L K+++Q +DL ++ S + N KD + HQ E+ SM + EKC K +
Sbjct: 846 MDILFKKLKQKFNDLVAEKEAVSSECV-----NLAKDNEVLHQ-ELLSMRNVQEKCEKLE 899
Query: 737 SDVDSTQTSSLNM 749
D + LN+
Sbjct: 900 KDKKMLEEEVLNL 912
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 33.1 bits (74), Expect = 1.8
Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 677 LTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQ 736
+ +L K+++Q +DL ++ S + N KD + HQ E+ SM + EKC K +
Sbjct: 739 MDILFKKLKQKFNDLVAEKEAVSSECV-----NLAKDNEVLHQ-ELLSMRNVQEKCEKLE 792
Query: 737 SDVDSTQTSSLNM 749
D + LN+
Sbjct: 793 KDKKMLEEEVLNL 805
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 33.1 bits (74), Expect = 1.8
Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 677 LTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQ 736
+ +L K+++Q +DL ++ S + N KD + HQ E+ SM + EKC K +
Sbjct: 846 MDILFKKLKQKFNDLVAEKEAVSSECV-----NLAKDNEVLHQ-ELLSMRNVQEKCEKLE 899
Query: 737 SDVDSTQTSSLNM 749
D + LN+
Sbjct: 900 KDKKMLEEEVLNL 912
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 32.7 bits (73), Expect = 2.3
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 1188 PLKEADTQDSREPRREKPRRKKR-PAKQPLQQAAPSDSDGSSHGISSHGSCQGTHPEPRT 1246
P +E + + SR P +E+ RR+ R P+K+ ++ + S S+ H S + Q + PR
Sbjct: 551 PSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRA 610
Query: 1247 A 1247
+
Sbjct: 611 S 611
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 32.7 bits (73), Expect = 2.3
Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 9/149 (6%)
Query: 342 QEMEEACSTLAQIQRLVAEPPKPDVATVDCESETTSVEIASNPEDTWDSKTWLQKYGLKA 401
+++E +T A+++R A+ + D+A ++ E + E T +T QK
Sbjct: 1132 EKLEAERTTRAKMERERADLTQ-DLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDM 1190
Query: 402 QKLSLYDVLADCSF--RHADGVVDIKAKPEN-ESVQTSAETNKKTVHAKYCSRFVHAPWK 458
++ +L+ S RHAD + +++ + EN + V+ E +K + +
Sbjct: 1191 EEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVE-- 1248
Query: 459 DGSLVHVNITKEK-CKWYSERIHTALARI 486
+ EK C Y ER+H A A++
Sbjct: 1249 --QMTRAKANAEKLCTLYEERLHEATAKL 1275
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 32.7 bits (73), Expect = 2.3
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 727 STPEKCAKPQSDVDSTQTSSLN--------MLKGPWGLSDQKVQKK--KVLH--AESTKT 774
+TP+K KP+ + Q S+L +L PW L++ +VQ KVL E +
Sbjct: 1193 TTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERK 1252
Query: 775 SLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEK--VTREG 832
++ + S R S ++ + + RT S K+ + E S EK T +G
Sbjct: 1253 KVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKG 1312
Query: 833 SQVYDHDSSDVSSE 846
D S DV +
Sbjct: 1313 KAKRDKASGDVKEK 1326
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 32.7 bits (73), Expect = 2.3
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 727 STPEKCAKPQSDVDSTQTSSLN--------MLKGPWGLSDQKVQKK--KVLH--AESTKT 774
+TP+K KP+ + Q S+L +L PW L++ +VQ KVL E +
Sbjct: 1232 TTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERK 1291
Query: 775 SLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEK--VTREG 832
++ + S R S ++ + + RT S K+ + E S EK T +G
Sbjct: 1292 KVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKG 1351
Query: 833 SQVYDHDSSDVSSE 846
D S DV +
Sbjct: 1352 KAKRDKASGDVKEK 1365
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 32.7 bits (73), Expect = 2.3
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 727 STPEKCAKPQSDVDSTQTSSLN--------MLKGPWGLSDQKVQKK--KVLH--AESTKT 774
+TP+K KP+ + Q S+L +L PW L++ +VQ KVL E +
Sbjct: 1269 TTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERK 1328
Query: 775 SLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEK--VTREG 832
++ + S R S ++ + + RT S K+ + E S EK T +G
Sbjct: 1329 KVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKG 1388
Query: 833 SQVYDHDSSDVSSE 846
D S DV +
Sbjct: 1389 KAKRDKASGDVKEK 1402
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 32.7 bits (73), Expect = 2.3
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 727 STPEKCAKPQSDVDSTQTSSLN--------MLKGPWGLSDQKVQKK--KVLH--AESTKT 774
+TP+K KP+ + Q S+L +L PW L++ +VQ KVL E +
Sbjct: 1192 TTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERK 1251
Query: 775 SLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEK--VTREG 832
++ + S R S ++ + + RT S K+ + E S EK T +G
Sbjct: 1252 KVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKG 1311
Query: 833 SQVYDHDSSDVSSE 846
D S DV +
Sbjct: 1312 KAKRDKASGDVKEK 1325
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 32.7 bits (73), Expect = 2.3
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 727 STPEKCAKPQSDVDSTQTSSLN--------MLKGPWGLSDQKVQKK--KVLH--AESTKT 774
+TP+K KP+ + Q S+L +L PW L++ +VQ KVL E +
Sbjct: 1231 TTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERK 1290
Query: 775 SLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEK--VTREG 832
++ + S R S ++ + + RT S K+ + E S EK T +G
Sbjct: 1291 KVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKG 1350
Query: 833 SQVYDHDSSDVSSE 846
D S DV +
Sbjct: 1351 KAKRDKASGDVKEK 1364
>gi|116875848 KIAA1946 [Homo sapiens]
Length = 826
Score = 32.7 bits (73), Expect = 2.3
Identities = 34/151 (22%), Positives = 58/151 (38%), Gaps = 7/151 (4%)
Query: 708 YNAEKDGDSKHQ-KEICSMISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKV 766
Y+ +K SK + +E SM+ T + DV + N + P + V K+
Sbjct: 435 YSPQKKEPSKAETEERVSMVKTRDDFKIYNEDVSFLSVNQNNYSRNPTQSLEPNVGSKQP 494
Query: 767 LHAESTKTSLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAE------EWL 820
H + +S L R +E G S+ + + + ++IL E L
Sbjct: 495 KHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPEQLMHIYSQPIAILQTSDLFSTPEQL 554
Query: 821 DDKSSEKVTREGSQVYDHDSSDVSSENWLKT 851
S + R+G VY V+ EN+ +T
Sbjct: 555 HTAKSATLPRKGQLVYGQLMEPVNRENFTQT 585
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 32.7 bits (73), Expect = 2.3
Identities = 38/155 (24%), Positives = 62/155 (40%), Gaps = 9/155 (5%)
Query: 724 SMISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRSQMSS 783
S I+ P K PQ D +T + +G +K++++K E + RSQ+S
Sbjct: 211 SPIALPVKQEPPQIDAVKRRTLPAWIREGL-----EKMEREKQKKLEKERMEQQRSQLSK 265
Query: 784 LRSSACSERKDGLSNASSRRTAL-SDKEMSILLAEEWLDDKSSEKVTREGSQVYDHDSSD 842
A + + G +R+ SD+E E ++ SS KVTR S V + SD
Sbjct: 266 KEKKATEDAEGGDGPRLPQRSKFDSDEEEE---DTENVEAASSGKVTRSPSPVPQEEHSD 322
Query: 843 VSSENWLKTYGLVAKKLTLMDALSVAAVPHSSTYV 877
K Y ++ L+ + + YV
Sbjct: 323 PEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYV 357
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 32.7 bits (73), Expect = 2.3
Identities = 38/155 (24%), Positives = 62/155 (40%), Gaps = 9/155 (5%)
Query: 724 SMISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRSQMSS 783
S I+ P K PQ D +T + +G +K++++K E + RSQ+S
Sbjct: 211 SPIALPVKQEPPQIDAVKRRTLPAWIREGL-----EKMEREKQKKLEKERMEQQRSQLSK 265
Query: 784 LRSSACSERKDGLSNASSRRTAL-SDKEMSILLAEEWLDDKSSEKVTREGSQVYDHDSSD 842
A + + G +R+ SD+E E ++ SS KVTR S V + SD
Sbjct: 266 KEKKATEDAEGGDGPRLPQRSKFDSDEEEE---DTENVEAASSGKVTRSPSPVPQEEHSD 322
Query: 843 VSSENWLKTYGLVAKKLTLMDALSVAAVPHSSTYV 877
K Y ++ L+ + + YV
Sbjct: 323 PEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYV 357
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,700,790
Number of Sequences: 37866
Number of extensions: 2251076
Number of successful extensions: 8448
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 8336
Number of HSP's gapped (non-prelim): 190
length of query: 1294
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1180
effective length of database: 13,930,794
effective search space: 16438336920
effective search space used: 16438336920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.