Guide to the Human Genome
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Search of human proteins with 239753245

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo
sapiens]
         (710 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]  1352   0.0  
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]       881   0.0  
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]       827   0.0  
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po...   664   0.0  
gi|124517695 ankyrin repeat domain 36B [Homo sapiens]                 612   e-175
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ...   493   e-139
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po...   294   2e-79
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]       197   4e-50
gi|239748832 PREDICTED: hypothetical protein XP_002346815 [Homo ...   125   1e-28
gi|115495445 ankyrin repeat domain 30A [Homo sapiens]                 108   1e-23
gi|222537750 ankyrin repeat domain 30B [Homo sapiens]                 102   2e-21
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo...    98   2e-20
gi|134133226 protein expressed in prostate, ovary, testis, and p...    95   3e-19
gi|113413200 PREDICTED: similar to protein expressed in prostate...    93   7e-19
gi|88953571 PREDICTED: similar to protein expressed in prostate,...    93   7e-19
gi|153791352 prostate, ovary, testis expressed protein on chromo...    92   2e-18
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa...    91   5e-18
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa...    91   5e-18
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap...    89   1e-17
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap...    89   1e-17
gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]            88   2e-17
gi|239741769 PREDICTED: similar to protein expressed in prostate...    87   4e-17
gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]        87   5e-17
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]        87   5e-17
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo...    87   5e-17
gi|224282147 prostate-specific P704P [Homo sapiens]                    87   7e-17
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo...    86   9e-17
gi|52856430 protein expressed in prostate, ovary, testis, and pl...    86   1e-16
gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens]            86   2e-16
gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ...    86   2e-16

>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
          Length = 710

 Score = 1352 bits (3500), Expect = 0.0
 Identities = 710/710 (100%), Positives = 710/710 (100%)

Query: 1   MGDHGVSLLGYNVQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVT 60
           MGDHGVSLLGYNVQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVT
Sbjct: 1   MGDHGVSLLGYNVQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVT 60

Query: 61  LGEKDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEG 120
           LGEKDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEG
Sbjct: 61  LGEKDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEG 120

Query: 121 QQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALN 180
           QQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALN
Sbjct: 121 QQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALN 180

Query: 181 TATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATS 240
           TATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATS
Sbjct: 181 TATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATS 240

Query: 241 DEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQ 300
           DEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQ
Sbjct: 241 DEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQ 300

Query: 301 PPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEI 360
           PPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEI
Sbjct: 301 PPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEI 360

Query: 361 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA 420
           SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA
Sbjct: 361 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA 420

Query: 421 RGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDE 480
           RGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDE
Sbjct: 421 RGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDE 480

Query: 481 EDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKP 540
           EDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKP
Sbjct: 481 EDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKP 540

Query: 541 ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISG 600
           ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISG
Sbjct: 541 ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISG 600

Query: 601 TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATE 660
           TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATE
Sbjct: 601 TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATE 660

Query: 661 IKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTGNLAIYI 710
           IKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTGNLAIYI
Sbjct: 661 IKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTGNLAIYI 710


>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 948

 Score =  881 bits (2277), Expect = 0.0
 Identities = 494/646 (76%), Positives = 526/646 (81%), Gaps = 34/646 (5%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPAEKATSD+KDSVSNIATEIKEG  SGTVS QKQ A+K    +K S+ NIAT I
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
             G +SGTVS QKQ A K    K  S LN AT I  G + GTVSSQKQ A KAT+D+  S
Sbjct: 324 KKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383

Query: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
             NIATEIKDG + GTVSSQK+PALKAT+DE+DS SNI  E KDGE S TVSSQK PALK
Sbjct: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443

Query: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
           AT+ ++DSV NIA E KDGEKS TVS  +PP L AT DE+ S+L+IAR  K+GEK+R VS
Sbjct: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503

Query: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
           SRKKPA KATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD
Sbjct: 504 SRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 563

Query: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
           GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS
Sbjct: 564 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 623

Query: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
           NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT
Sbjct: 624 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 683

Query: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
           SDEKDSVLNIARGKKDGEKTRTVSS+K P LKATSDE+DSVL IARE KDGEKSRTVSS+
Sbjct: 684 SDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSE 743

Query: 572 ----------------------------------KQPALKAICDKEDSVPNMATEKKDEQ 597
                                             K+PALKA  D++DSV  +A EKKD +
Sbjct: 744 KPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGE 803

Query: 598 ISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNI 657
            S TVSSQKQPALKA  DK+DSV N+ TE KD Q SGTVSSQKQPA KATS KKDSVSNI
Sbjct: 804 KSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNI 863

Query: 658 ATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 703
            TEIKDGQ  GTVSPQKQSAQKVIFKKKVSLLNIATRITGG KSGT
Sbjct: 864 PTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGT 909



 Score =  853 bits (2205), Expect = 0.0
 Identities = 474/616 (76%), Positives = 499/616 (81%), Gaps = 34/616 (5%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPAEKATSDEKDSVSNIATEIK+GQQSGTVSPQKQSA+KVIFKKKVSLLNIATRI
Sbjct: 298 VSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRI 357

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
           MGGGKSGTVSSQKQPASK  SDKTDSALN ATEIKDGLQCGTVSSQKQ ALKATTDEE S
Sbjct: 358 MGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 417

Query: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
           VSNIATEIKDGEKSGTVSSQK+PALKAT+DEKDS SNI  E KDGE S TVSSQKPPAL 
Sbjct: 418 VSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALT 477

Query: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
           ATS +E SVL+IARE KDGEKSRTVS  + P  KAT DEKDS  NI RGKK+GE +R+VS
Sbjct: 478 ATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVS 537

Query: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAR---- 387
           S+K P LK TSDE+DS   I R  KDGE SR VSS+KPP LK +SDE+DSVL IAR    
Sbjct: 538 SQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKY 597

Query: 388 ------------------------------ENKDGEKSRTVSSEKPPGLKASSDEKDSVL 417
                                         E KDGE SR VSS+KPP LK +SDE+DSVL
Sbjct: 598 GEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVL 657

Query: 418 NIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGT 477
            IAR  K GEK++ VSS K P L+ATSDEKDS  NI R KKDGE +R VSSQKPP LK T
Sbjct: 658 GIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKAT 717

Query: 478 SDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSR 537
           SDEEDSVL IARENKDGEKSRTVSSEKP GLKATS EKDSVLNIARGKK GEKT+ VSSR
Sbjct: 718 SDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSR 777

Query: 538 KKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQ 597
           KKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQ
Sbjct: 778 KKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQ 837

Query: 598 ISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNI 657
           ISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVS QKQ A K    KK S+ NI
Sbjct: 838 ISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNI 897

Query: 658 ATEIKDGQIRGTVSPQ 673
           AT I  G   GTV  Q
Sbjct: 898 ATRITGGWKSGTVIRQ 913



 Score =  609 bits (1571), Expect = e-174
 Identities = 362/596 (60%), Positives = 419/596 (70%), Gaps = 6/596 (1%)

Query: 100 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGT 159
           E     E  +V      +    Q   VSP++        K +    +I+TR +GG  S T
Sbjct: 170 ENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRD---HISTRFLGGMDSLT 226

Query: 160 VS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIA 216
            S   S++ P S     + D +   A   KD    G VSSQKQ A KAT+D++ SVSNIA
Sbjct: 227 SSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286

Query: 217 TEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVK 276
           TEIK+G  SGTVSSQK+PA KATSDEKDS SNI  E K G+ S TVS QK  A K    K
Sbjct: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKK 346

Query: 277 EDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKP 336
           + S+LNIA     G KS TVS  + P  KAT D+ DS LNIA   K+G +   VSS+K+P
Sbjct: 347 KVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQP 406

Query: 337 ALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSR 396
           ALKAT+DE+DS SNI    KDGE S  VSSQK P LK T+DE+DSV  IA E KDGEKS 
Sbjct: 407 ALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSG 466

Query: 397 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 456
           TVSS+KPP L A+SDE+ SVL+IAR  K GEK++ VSSRKKP+ +ATSDEKDSFSNITR 
Sbjct: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRG 526

Query: 457 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 516
           KKDGEISRKVSSQKPP LKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA+SDEKD
Sbjct: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 586

Query: 517 SVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPAL 576
           SVLNIARGKK GEKT+ VSSRKKP+L+ATSDEKDS   I REKKDGE SR VSSQK PAL
Sbjct: 587 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646

Query: 577 KAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 636
           K   D+EDSV  +A E KD + S TVSS+K P LKATSD+KDSV NI    KDG+++ TV
Sbjct: 647 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 706

Query: 637 SSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIA 692
           SSQK P  KATS ++DSV +IA E KDG+   TVS +K S  K    +K S+LNIA
Sbjct: 707 SSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIA 762



 Score =  451 bits (1161), Expect = e-127
 Identities = 278/514 (54%), Positives = 329/514 (64%)

Query: 190 QCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNI 249
           Q   VS ++      T  +   +S       D   S   SS++ P    T  E D  S  
Sbjct: 192 QKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKA 251

Query: 250 TREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRD 309
              +KD      VSSQK PA KATS  +DSV NIA E K+G  S TVS  + P  KAT D
Sbjct: 252 AMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSD 311

Query: 310 EKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKP 369
           EKDS+ NIA   K G+++  VS +K+ A K    +K S  NI      G  S  VSSQK 
Sbjct: 312 EKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQ 371

Query: 370 PTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKT 429
           P  K TSD+ DS L IA E KDG +  TVSS+K P LKA++DE+DSV NIA   K GEK+
Sbjct: 372 PASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKS 431

Query: 430 KRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIAR 489
             VSS+K+P+L+AT+DEKDS SNI  E KDGE S  VSSQKPPAL  TSDEE SVL IAR
Sbjct: 432 GTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIAR 491

Query: 490 ENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEK 549
           ENKDGEKSRTVSS K P  KATSDEKDS  NI RGKKDGE +R VSS+K P LK TSDE+
Sbjct: 492 ENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEE 551

Query: 550 DSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPA 609
           DSVL IARE KDGEKSRTVSS+K P LKA  D++DSV N+A  KK  + +  VSS+K+P+
Sbjct: 552 DSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPS 611

Query: 610 LKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGT 669
           L+ATSD+KDS SNI  E KDG+ S  VSSQK PA K TS ++DSV  IA E KDG+   T
Sbjct: 612 LEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRT 671

Query: 670 VSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 703
           VS +K    K    +K S+LNIA     G K+ T
Sbjct: 672 VSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRT 705



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 35/65 (53%), Positives = 41/65 (63%)

Query: 596 EQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 655
           E  S  VSSQKQPALK TSDK DSVSN  TEIKD Q+SGTV    +     +  + D+V+
Sbjct: 14  ETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVA 73

Query: 656 NIATE 660
              TE
Sbjct: 74  QPVTE 78



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 2/99 (2%)

Query: 565 SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP 624
           S  VSSQKQPALK   DK+DSV N ATE KDEQ SGTV    +  L  +  + D+V+   
Sbjct: 17  SLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPV 76

Query: 625 TEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKD 663
           TE +   +S  +S    P  K  S +  S+ ++   +++
Sbjct: 77  TENEFSLESEIISKLYIPKRKIISPR--SIKDVLPPVEE 113


>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 1524

 Score =  827 bits (2136), Expect = 0.0
 Identities = 467/612 (76%), Positives = 500/612 (81%), Gaps = 8/612 (1%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPAEKATSD+KDSVSNIATEIKEG  SGTVS QKQ A+K    +K S+ NIAT I
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
             G +SGTVS QKQ A K    K  S LN AT I  G + GTVSSQKQ A KAT+D+  S
Sbjct: 324 KKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383

Query: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
             NIATEIKDG + GTVSSQK+PALKAT+DE+DS SNI  E KDGE S TVSSQK PALK
Sbjct: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443

Query: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
           AT+ ++DSV NIA E KDGEKS TVS  +PP L AT DE+ S+L+IAR  K+GEK+R VS
Sbjct: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503

Query: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
           SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD
Sbjct: 504 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 563

Query: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
           GEKSRTVSSEKPPGLKASS EKDSVLNIARGKK GEKTKRVSSRKKPSLEATSDEKDSFS
Sbjct: 564 GEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFS 623

Query: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
           NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT
Sbjct: 624 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 683

Query: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
           SDEKDSVLNIARGKKDGEKTRTVSS K+PALKA  D++DSV  +A EKKD + S TVS Q
Sbjct: 684 SDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQ 743

Query: 572 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 631
           KQPALKA  DK+DSV N+ TE KD Q SGTVSSQKQPA KATS KKDSVSNI TEIKDGQ
Sbjct: 744 KQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQ 803

Query: 632 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNI 691
             GT   +        +V  D +    T +        VSPQKQSAQKVIFKKKVSLLNI
Sbjct: 804 IRGTGILE-----YTFNVMFDQIEEKFTSLNKS---AGVSPQKQSAQKVIFKKKVSLLNI 855

Query: 692 ATRITGGGKSGT 703
           ATRITGG KSGT
Sbjct: 856 ATRITGGWKSGT 867



 Score =  620 bits (1600), Expect = e-177
 Identities = 384/669 (57%), Positives = 427/669 (63%), Gaps = 145/669 (21%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPAEKATSDEKDSVSNIATEIK+GQQSGTVSPQKQSA KVIFKKKVSLLNIATRI
Sbjct: 298 VSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI 357

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
           MGGGKSGTVSSQKQPASK  SDKTDSALN ATEIKDGLQCGTVSSQKQ ALKATTDEE S
Sbjct: 358 MGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 417

Query: 212 VS----------------------------------NIATEIKDGEKSGTVSSQK----- 232
           VS                                  NIATEIKDGEKSGTVSSQK     
Sbjct: 418 VSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALT 477

Query: 233 -----------------------------KPALKATSDEKDSFSNITREKKDGEISRTVS 263
                                        KPALKATSDEKDSFSNITR KKDGEISR VS
Sbjct: 478 ATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVS 537

Query: 264 SQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKN 323
           SQKPP LK TS +EDSVL IARE KDGEKSRTVS ++PPGLKA+  EKDS+LNIARGKK+
Sbjct: 538 SQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKD 597

Query: 324 GEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVL 383
           GEKT+RVSSRKKP+L+ATSDEKDSFSNITR KKDGEISRKVSSQKPP LKGTSDEEDSVL
Sbjct: 598 GEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVL 657

Query: 384 GIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSS--------- 434
           GIARENKDGEKSRTVSSEKPPGLKA+SDEKDSVLNIARGKK GEKT+ VSS         
Sbjct: 658 GIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAI 717

Query: 435 -------------------------RKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQ 469
                                    +K+P+L+ATSD+KDS SNI  E KDG+ S  VSSQ
Sbjct: 718 CDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQ 777

Query: 470 KPPALKGTSDEEDSVLGIARENKDGE--------------------------KSRTVSSE 503
           K PA K TS ++DSV  IA E KDG+                          KS  VS +
Sbjct: 778 KQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQ 837

Query: 504 KPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGE 563
           K    K    +K S+LNIA     G K+ T      P LKAT + K+SVL  A + KD +
Sbjct: 838 KQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQ 897

Query: 564 KSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQ--PALKATSDKKDSVS 621
            S       +               MA+E + +++    ++Q Q    + +  D  D + 
Sbjct: 898 TSTPAEQDLE---------------MASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQ 942

Query: 622 NIPTEIKDG 630
           +  T  +DG
Sbjct: 943 SSQTVSEDG 951



 Score =  454 bits (1168), Expect = e-127
 Identities = 279/514 (54%), Positives = 330/514 (64%)

Query: 190 QCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNI 249
           Q   VS ++      T  +   +S       D   S   SS++ P    T  E D  S  
Sbjct: 192 QKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKA 251

Query: 250 TREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRD 309
              +KD      VSSQK PA KATS  +DSV NIA E K+G  S TVS  + P  KAT D
Sbjct: 252 AMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSD 311

Query: 310 EKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKP 369
           EKDS+ NIA   K G+++  VS +K+ A K    +K S  NI      G  S  VSSQK 
Sbjct: 312 EKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQ 371

Query: 370 PTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKT 429
           P  K TSD+ DS L IA E KDG +  TVSS+K P LKA++DE+DSV NIA   K GEK+
Sbjct: 372 PASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKS 431

Query: 430 KRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIAR 489
             VSS+K+P+L+AT+DEKDS SNI  E KDGE S  VSSQKPPAL  TSDEE SVL IAR
Sbjct: 432 GTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIAR 491

Query: 490 ENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEK 549
           ENKDGEKSRTVSS K P LKATSDEKDS  NI RGKKDGE +R VSS+K P LK TSDE+
Sbjct: 492 ENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEE 551

Query: 550 DSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPA 609
           DSVL IARE KDGEKSRTVSS+K P LKA   ++DSV N+A  KKD + +  VSS+K+P+
Sbjct: 552 DSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPS 611

Query: 610 LKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGT 669
           L+ATSD+KDS SNI  E KDG+ S  VSSQK PA K TS ++DSV  IA E KDG+   T
Sbjct: 612 LEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRT 671

Query: 670 VSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 703
           VS +K    K    +K S+LNIA     G K+ T
Sbjct: 672 VSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRT 705



 Score =  272 bits (695), Expect = 9e-73
 Identities = 200/498 (40%), Positives = 259/498 (52%), Gaps = 39/498 (7%)

Query: 15  ILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHN 74
           + ++  P L A S  +  ++    + K    +     R    L  T  EKD         
Sbjct: 468 VSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDS-------- 519

Query: 75  IDVFSRDVYGKLAEDYA--MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQS 132
              FS    GK   + +  +S QK P  K TSDE+DSV  IA E K+G++S TVS +K  
Sbjct: 520 ---FSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 576

Query: 133 AQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCG 192
             K    +K S+LNIA     G K+  VSS+K+P+ +  SD+ DS  N   E KDG    
Sbjct: 577 GLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISR 636

Query: 193 TVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITRE 252
            VSSQK  ALK T+DEE SV  IA E KDGEKS TVSS+K P LKATSDEKDS  NI R 
Sbjct: 637 KVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARG 696

Query: 253 KKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKD 312
           KKDGE +RTVSS K PALKA   KEDSV N+A EKKD + S TVS  + P LKAT D+KD
Sbjct: 697 KKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKD 756

Query: 313 SLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEI------------ 360
           S+ NI    K+G+++  VSS+K+PA KATS +KDS SNI    KDG+I            
Sbjct: 757 SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNV 816

Query: 361 --------------SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 406
                         S  VS QK    K    ++ S+L IA     G KS T   E  P L
Sbjct: 817 MFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTL 876

Query: 407 KASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV 466
           KA+ + K+SVLN A   K  + +       + + E      + + N   + K+   SR  
Sbjct: 877 KATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDD 936

Query: 467 SSQKPPALKGTSDEEDSV 484
                 + +  S++ DS+
Sbjct: 937 LDDIIQSSQTVSEDGDSL 954



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 35/65 (53%), Positives = 41/65 (63%)

Query: 596 EQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 655
           E  S  VSSQKQPALK TSDK DSVSN  TEIKD Q+SGTV    +     +  + D+V+
Sbjct: 14  ETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVA 73

Query: 656 NIATE 660
              TE
Sbjct: 74  QPVTE 78



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 2/99 (2%)

Query: 565 SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP 624
           S  VSSQKQPALK   DK+DSV N ATE KDEQ SGTV    +  L  +  + D+V+   
Sbjct: 17  SLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPV 76

Query: 625 TEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKD 663
           TE +   +S  +S    P  K  S +  S+ ++   +++
Sbjct: 77  TENEFSLESEIISKLYIPKRKIISPR--SIKDVLPPVEE 113


>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
           polyclonal antibodies [Homo sapiens]
          Length = 1430

 Score =  664 bits (1712), Expect = 0.0
 Identities = 395/608 (64%), Positives = 444/608 (73%), Gaps = 8/608 (1%)

Query: 100 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLN-IATRIMGGGKSG 158
           E  T  E  +V      +    Q   VSP+    Q  +F   V   + I+TR +G   S 
Sbjct: 170 ENGTLFEDQNVDKEGKALPATGQKANVSPE----QPPLFTHTVKDSDHISTRFLGSMDSL 225

Query: 159 TVS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNI 215
           T S   S++ P S     + D +   A   KD    G VSSQKQ A KAT+D++ SVSNI
Sbjct: 226 TSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNI 285

Query: 216 ATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSV 275
           ATEIK+G  SGTVSSQK+PA KATSDEKDS SNI  E K+G+ S TVS QK  A K    
Sbjct: 286 ATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFK 345

Query: 276 KEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKK 335
           K+ S+LNIA     G KS TVS  + P  KAT D+ DS LNIA   K+G +   VSS+K+
Sbjct: 346 KKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQ 405

Query: 336 PALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKS 395
           PALKAT+DE+DS SNI    KDGE S  VSSQK P LK T+DEEDSVL IA E KDGEKS
Sbjct: 406 PALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKS 465

Query: 396 RTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITR 455
            TVSS+K P LKA++DE+DSV  IA   K GEK+  VSSRKKP+L+ATSDEKDSFSNITR
Sbjct: 466 ETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITR 525

Query: 456 EKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEK 515
           EKKDGEISR VSSQKPPALK TSDEEDSVL IARE KDGEKSRTVSSE+PPGLKAT DEK
Sbjct: 526 EKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEK 585

Query: 516 DSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPA 575
           DS+LNIARGKK GEKTR VSS K+PALKATSD+++SV  +A E KD + S TVSSQKQPA
Sbjct: 586 DSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPA 645

Query: 576 LKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGT 635
           LKA  DK+DSV N+ TE KD Q SGTVSSQKQ A KATS KKDSVSNI TEIKDGQ  GT
Sbjct: 646 LKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGT 705

Query: 636 VSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRI 695
           VSSQ+QPA KAT  +KDSVSNIA EIKDG+  GTVSPQKQSAQKVIFKKKVSLLNIATRI
Sbjct: 706 VSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRI 765

Query: 696 TGGGKSGT 703
           TGG KSGT
Sbjct: 766 TGGWKSGT 773



 Score =  630 bits (1624), Expect = e-180
 Identities = 363/572 (63%), Positives = 420/572 (73%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPAEKATSD+KDSVSNIATEIKEG  SGTVS QKQ A+K    +K S+ NIAT I
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
             G +SGTVS QKQ A K    K  S LN AT I  G + GTVSSQKQ   KAT+D+  S
Sbjct: 324 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDS 383

Query: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
             NIATEIKDG + GTVSSQK+PALKAT+DE+DS SNI  E KDGE S TVSSQK PALK
Sbjct: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443

Query: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
           AT+ +EDSVLNIA E KDGEKS TVS  + P LKAT DE+DS+  IA   K+GEK+  VS
Sbjct: 444 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 503

Query: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
           SRKKPALKATSDEKDSFSNITR KKDGEISR VSSQKPP LK TSDEEDSVL IARE KD
Sbjct: 504 SRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKD 563

Query: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
           GEKSRTVSSE+PPGLKA+ DEKDS+LNIARGKKYGEKT+RVSS K+P+L+ATSD+++S  
Sbjct: 564 GEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVP 623

Query: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
           N+  E KD +IS  VSSQK PALK TSD++DSV  I  E KDG++S TVSS+K    KAT
Sbjct: 624 NMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKAT 683

Query: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
           S +KDSV NIA   KDG+   TVSS+++PALKAT DEKDSV  IARE KDGEKS TVS Q
Sbjct: 684 SVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQ 743

Query: 572 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 631
           KQ A K I  K+ S+ N+AT       SGT   +  P LKAT + K+SV N  T++KD Q
Sbjct: 744 KQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQ 803

Query: 632 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKD 663
            S       + A +    + +   N   ++K+
Sbjct: 804 TSTPAEQDLEMASEGEQKRLEEYENNQPQVKN 835



 Score =  546 bits (1408), Expect = e-155
 Identities = 336/572 (58%), Positives = 379/572 (66%), Gaps = 81/572 (14%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSA KVIFKKKVSLLNIATRI
Sbjct: 298 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI 357

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
            GGGKSGTVSSQKQP SK  SDKTDSALN ATEIKDGLQCGTVSSQKQ ALKATTDEE S
Sbjct: 358 TGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 417

Query: 212 VSNIATEI---------------------------------------------------- 219
           VSNIATEI                                                    
Sbjct: 418 VSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 477

Query: 220 ----------------KDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVS 263
                           KDGEKSGTVSS+KKPALKATSDEKDSFSNITREKKDGEISRTVS
Sbjct: 478 ATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVS 537

Query: 264 SQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKN 323
           SQKPPALKATS +EDSVL+IARE+KDGEKSRTVS +QPPGLKATRDEKDSLLNIARGKK 
Sbjct: 538 SQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKY 597

Query: 324 GEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVL 383
           GEKTRRVSS K+PALKATSD+++S  N+    KD +IS  VSSQK P LK TSD++DSV 
Sbjct: 598 GEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVS 657

Query: 384 GIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEAT 443
            I  E KDG++S TVSS+K    KA+S +KDSV NIA   K G+    VSS+++P+L+AT
Sbjct: 658 NIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKAT 717

Query: 444 SDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSE 503
            DEKDS SNI RE KDGE S  VS QK  A K    ++ S+L IA     G KS T   E
Sbjct: 718 GDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPE 777

Query: 504 KPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGE 563
             P LKAT + K+SVLN A   KD +              +T  E+D  +    E+K  E
Sbjct: 778 NLPTLKATIENKNSVLNTATKMKDVQ-------------TSTPAEQDLEMASEGEQKRLE 824

Query: 564 KSRTVSSQKQPALKAICDKEDSVPNMATEKKD 595
           +      Q +  + +  D +D + +  T  +D
Sbjct: 825 EYENNQPQVKNQIHSRDDLDDIIQSSQTVSED 856



 Score =  308 bits (790), Expect = 9e-84
 Identities = 208/461 (45%), Positives = 261/461 (56%), Gaps = 68/461 (14%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPA KAT+DE+DSVSNIATEIK+G++SGTVS QKQ A K    ++ S+LNIAT I
Sbjct: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEI 459

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
             G KS TVSSQKQPA K  +D+ DS    ATEIKDG + GTVSS+K+ ALKAT+DE+ S
Sbjct: 460 KDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDS 519

Query: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
            SNI  E KDGE S TVSSQK PALKATSDE+DS  +I RE+KDGE SRTVSS++PP LK
Sbjct: 520 FSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 579

Query: 272 ATSVKEDSVLNIAREKKDGEKSR----------------------------------TVS 297
           AT  ++DS+LNIAR KK GEK+R                                  TVS
Sbjct: 580 ATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVS 639

Query: 298 FDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKK---------------------- 335
             + P LKAT D+KDS+ NI    K+G+++  VSS+K+                      
Sbjct: 640 SQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKD 699

Query: 336 ------------PALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVL 383
                       PALKAT DEKDS SNI R  KDGE S  VS QK    K    ++ S+L
Sbjct: 700 GQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLL 759

Query: 384 GIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEAT 443
            IA     G KS T   E  P LKA+ + K+SVLN A   K  + +       + + E  
Sbjct: 760 NIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGE 819

Query: 444 SDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 484
               + + N   + K+   SR        + +  S++ DS+
Sbjct: 820 QKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 860



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 35/65 (53%), Positives = 41/65 (63%)

Query: 596 EQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 655
           E  S  VSSQKQPALK TSDK DSVSN  TEIKD Q+SGTV    +     +  + D+V+
Sbjct: 14  ETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVA 73

Query: 656 NIATE 660
              TE
Sbjct: 74  QPVTE 78



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 39/99 (39%), Positives = 54/99 (54%), Gaps = 2/99 (2%)

Query: 565 SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP 624
           S  VSSQKQPALK   DK DSV N ATE KDEQ SGTV    +  L  +  + D+V+   
Sbjct: 17  SLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPV 76

Query: 625 TEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKD 663
           TE +   +S  +S    P  K  S +  S+ ++   +++
Sbjct: 77  TEDEFALESEIISKLYIPKRKIISPR--SIEDVLPPVEE 113


>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
          Length = 1121

 Score =  612 bits (1578), Expect = e-175
 Identities = 348/504 (69%), Positives = 388/504 (76%), Gaps = 13/504 (2%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI
Sbjct: 57  VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 116

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
           MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS
Sbjct: 117 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 176

Query: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
           VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK
Sbjct: 177 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 236

Query: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
           ATSVKEDSVLNIAREKKDGEKSRTVSF+QPPGLKATRDEKDSLLNIARGKK+GEKTRRVS
Sbjct: 237 ATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVS 296

Query: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
           S K+P+LKATSD++DS  N+    KD +IS  VS QK P LK TSD++DSV  I  E KD
Sbjct: 297 SHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKD 356

Query: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
           G++S TVSS+K P  KA+S +KDSV NIA   K G+    VSS+++P+L+ T DEKDS S
Sbjct: 357 GQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVS 416

Query: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
           NI RE KDGE S  VS QK  A K    ++ S+L IA     G KS T   E    LKAT
Sbjct: 417 NIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKAT 476

Query: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
            + KDSVLN A             ++ K    +T  E+D  +    E+K  E+      Q
Sbjct: 477 IENKDSVLNTA-------------TKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQ 523

Query: 572 KQPALKAICDKEDSVPNMATEKKD 595
            +  + +  D +D + +  T  +D
Sbjct: 524 VKNQIHSRDDLDDIIQSSQTVSED 547



 Score =  521 bits (1342), Expect = e-148
 Identities = 300/442 (67%), Positives = 336/442 (76%)

Query: 262 VSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGK 321
           +S QK  A KATS  +DSV NIA E K+G  S TVS  + P  KAT DEKDS+ NIA   
Sbjct: 23  LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82

Query: 322 KNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDS 381
           K G+++  VS +K+ A K    +K S  NI      G  S  VSSQK P  K  SD+ DS
Sbjct: 83  KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142

Query: 382 VLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLE 441
            L  A E KDG +  TVSS+K   LKA++DE+ SV NIA   K GEK+  VSS+KKP+L+
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202

Query: 442 ATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVS 501
           ATSDEKDSFSNITREKKDGEISR VSSQKPPALK TS +EDSVL IARE KDGEKSRTVS
Sbjct: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262

Query: 502 SEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKD 561
            E+PPGLKAT DEKDS+LNIARGKKDGEKTR VSS K+P+LKATSD++DSV  +A E KD
Sbjct: 263 FEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKD 322

Query: 562 GEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVS 621
            + S TVS QKQPALKA  DK+DSV N+ TE KD Q SGTVSSQKQPA KATS KKDSVS
Sbjct: 323 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 382

Query: 622 NIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVI 681
           NI TEIKDGQ  GTVSSQ++PA K T  +KDSVSNIA EIKDG+  GTVSPQKQSAQKVI
Sbjct: 383 NIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 442

Query: 682 FKKKVSLLNIATRITGGGKSGT 703
           FKKKVSLLNIATRITGGGKSGT
Sbjct: 443 FKKKVSLLNIATRITGGGKSGT 464



 Score =  506 bits (1302), Expect = e-143
 Identities = 297/504 (58%), Positives = 349/504 (69%)

Query: 160 VSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEI 219
           +S QKQ A K  SD  DS  N ATEIK+G   GTVSSQKQ A KAT+DE+ SVSNIATEI
Sbjct: 23  LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82

Query: 220 KDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDS 279
           K+G++SGTVS QK+ A K    +K S  NI      G  S TVSSQK PA K  S K DS
Sbjct: 83  KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142

Query: 280 VLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALK 339
            LN A E KDG +  TVS  +   LKAT DE+ S+ NIA   K+GEK+  VSS+KKPALK
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202

Query: 340 ATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVS 399
           ATSDEKDSFSNITR KKDGEISR VSSQKPP LK TS +EDSVL IARE KDGEKSRTVS
Sbjct: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262

Query: 400 SEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKD 459
            E+PPGLKA+ DEKDS+LNIARGKK GEKT+RVSS K+PSL+ATSD++DS  N+  E KD
Sbjct: 263 FEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKD 322

Query: 460 GEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVL 519
            +IS  VS QK PALK TSD++DSV  I  E KDG++S TVSS+K P  KATS +KDSV 
Sbjct: 323 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 382

Query: 520 NIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAI 579
           NIA   KDG+   TVSS+++PALK T DEKDSV  IARE KDGEKS TVS QKQ A K I
Sbjct: 383 NIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 442

Query: 580 CDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQ 639
             K+ S+ N+AT       SGT   +    LKAT + KDSV N  T++K+ Q S      
Sbjct: 443 FKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQD 502

Query: 640 KQPAWKATSVKKDSVSNIATEIKD 663
            + A +    + +   N   ++K+
Sbjct: 503 LEMASEGEQKRLEEYENNQPQVKN 526



 Score =  287 bits (734), Expect = 3e-77
 Identities = 186/393 (47%), Positives = 235/393 (59%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQ A KAT+DE+ SVSNIATEIK+G++SGTVS QK+ A K    +K S  NI    
Sbjct: 159 VSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREK 218

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
             G  S TVSSQK PA K  S K DS LN A E KDG +  TVS ++   LKAT DE+ S
Sbjct: 219 KDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDS 278

Query: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
           + NIA   KDGEK+  VSS K+P+LKATSD++DS  N+  E KD +IS TVS QK PALK
Sbjct: 279 LLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALK 338

Query: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
           ATS K+DSV NI  E KDG++S TVS  + P  KAT  +KDS+ NIA   K+G+    VS
Sbjct: 339 ATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVS 398

Query: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
           S+++PALK T DEKDS SNI R  KDGE S  VS QK    K    ++ S+L IA     
Sbjct: 399 SQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITG 458

Query: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
           G KS T   E    LKA+ + KDSVLN A   K  + +       + + E      + + 
Sbjct: 459 GGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYE 518

Query: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSV 484
           N   + K+   SR        + +  S++ DS+
Sbjct: 519 NNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 551



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 19/39 (48%), Positives = 24/39 (61%)

Query: 665 QIRGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 703
           ++R  +SPQKQ A+K     K S+ NIAT I  G  SGT
Sbjct: 18  RLRIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGT 56


>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
           sapiens]
          Length = 399

 Score =  493 bits (1268), Expect = e-139
 Identities = 272/350 (77%), Positives = 286/350 (81%), Gaps = 34/350 (9%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSA KVIFKKKVSLLNIATRI
Sbjct: 42  VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI 101

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
            GGGKSGTVSSQKQPASK  SDKTDSALN ATEIKDGLQCGTVSSQKQ ALKATTDEE S
Sbjct: 102 TGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 161

Query: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
           VSNIATEIKDGEKSGTVSSQK+PALKAT+DE+DS  NI  E KDGE S TVSSQK PALK
Sbjct: 162 VSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 221

Query: 272 ATSVKEDSV----------------------------------LNIAREKKDGEKSRTVS 297
           AT+ +EDSV                                   NI REKKDGE SRTV+
Sbjct: 222 ATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVT 281

Query: 298 FDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKD 357
            ++P GLKAT DE+DS+LNIARGK++GEKTRRVSSRKKPALKATSDEKDSFSNITR KKD
Sbjct: 282 SEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKD 341

Query: 358 GEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 407
           GE SR VSSQKPP LK TSDEEDSVL IARE KDGEKSRTVSSE+PPGLK
Sbjct: 342 GETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391



 Score =  473 bits (1217), Expect = e-133
 Identities = 266/385 (69%), Positives = 297/385 (77%)

Query: 125 TVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATE 184
           +VS QKQ A+K     K S+ NIAT I  G  SGTVSSQKQPA K  SD+ DS  N ATE
Sbjct: 7   SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66

Query: 185 IKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKD 244
           IK+G Q GTVS QKQ A K    ++ S+ NIAT I  G KSGTVSSQK+PA KATSD+ D
Sbjct: 67  IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126

Query: 245 SFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGL 304
           S  NI  E KDG    TVSSQK PALKAT+ +EDSV NIA E KDGEKS TVS  + P L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186

Query: 305 KATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKV 364
           KAT DE+DS+LNIA   K+GEK+  VSS+K+PALKAT+DE+DS S I    KDGE S  V
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246

Query: 365 SSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKK 424
           SS+K P LK TSDE+DS   I RE KDGE SRTV+SEKP GLKA+SDE+DSVLNIARGK+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306

Query: 425 YGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 484
            GEKT+RVSSRKKP+L+ATSDEKDSFSNITREKKDGE SR VSSQKPPALK TSDEEDSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366

Query: 485 LGIARENKDGEKSRTVSSEKPPGLK 509
           L IARE KDGEKSRTVSSE+PPGLK
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391



 Score =  463 bits (1191), Expect = e-130
 Identities = 262/389 (67%), Positives = 299/389 (76%)

Query: 191 CGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNIT 250
           C +VSSQKQ A KAT+D++ SVSNIATEIK+G  SGTVSSQK+PA KATSDEKDS SNI 
Sbjct: 5   CFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 64

Query: 251 REKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDE 310
            E K+G+ S TVS QK  A K    K+ S+LNIA     G KS TVS  + P  KAT D+
Sbjct: 65  TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124

Query: 311 KDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPP 370
            DS LNIA   K+G +   VSS+K+PALKAT+DE+DS SNI    KDGE S  VSSQK P
Sbjct: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184

Query: 371 TLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTK 430
            LK T+DEEDSVL IA E KDGEKS TVSS+K P LKA++DE+DSV  IA   K GEK+ 
Sbjct: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244

Query: 431 RVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARE 490
            VSSRKKP+L+ATSDEKDSFSNITREKKDGEISR V+S+KP  LK TSDEEDSVL IAR 
Sbjct: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304

Query: 491 NKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKD 550
            +DGEK+R VSS K P LKATSDEKDS  NI R KKDGE +RTVSS+K PALKATSDE+D
Sbjct: 305 KEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEED 364

Query: 551 SVLYIAREKKDGEKSRTVSSQKQPALKAI 579
           SVL IARE+KDGEKSRTVSS++ P LK +
Sbjct: 365 SVLSIAREEKDGEKSRTVSSEQPPGLKVM 393



 Score =  463 bits (1191), Expect = e-130
 Identities = 261/386 (67%), Positives = 298/386 (77%)

Query: 90  YAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIAT 149
           +++S QKQPAEKATSD+KDSVSNIATEIKEG  SGTVS QKQ A+K    +K S+ NIAT
Sbjct: 6   FSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIAT 65

Query: 150 RIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEE 209
            I  G +SGTVS QKQ A K    K  S LN AT I  G + GTVSSQKQ A KAT+D+ 
Sbjct: 66  EIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKT 125

Query: 210 GSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPA 269
            S  NIATEIKDG + GTVSSQK+PALKAT+DE+DS SNI  E KDGE S TVSSQK PA
Sbjct: 126 DSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPA 185

Query: 270 LKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRR 329
           LKAT+ +EDSVLNIA E KDGEKS TVS  + P LKAT DE+DS+  IA   K+GEK+  
Sbjct: 186 LKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGT 245

Query: 330 VSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAREN 389
           VSSRKKPALKATSDEKDSFSNITR KKDGEISR V+S+KP  LK TSDEEDSVL IAR  
Sbjct: 246 VSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGK 305

Query: 390 KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDS 449
           +DGEK+R VSS K P LKA+SDEKDS  NI R KK GE ++ VSS+K P+L+ATSDE+DS
Sbjct: 306 EDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDS 365

Query: 450 FSNITREKKDGEISRKVSSQKPPALK 475
             +I RE+KDGE SR VSS++PP LK
Sbjct: 366 VLSIAREEKDGEKSRTVSSEQPPGLK 391



 Score =  435 bits (1119), Expect = e-122
 Identities = 251/385 (65%), Positives = 291/385 (75%)

Query: 227 TVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIARE 286
           +VSSQK+PA KATSD+KDS SNI  E K+G IS TVSSQK PA KATS ++DSV NIA E
Sbjct: 7   SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66

Query: 287 KKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKD 346
            K+G++S TVS  +    K    +K SLLNIA     G K+  VSS+K+PA KATSD+ D
Sbjct: 67  IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126

Query: 347 SFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 406
           S  NI    KDG     VSSQK P LK T+DEEDSV  IA E KDGEKS TVSS+K P L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186

Query: 407 KASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV 466
           KA++DE+DSVLNIA   K GEK++ VSS+K+P+L+AT+DE+DS S I  E KDGE S  V
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246

Query: 467 SSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKK 526
           SS+K PALK TSDE+DS   I RE KDGE SRTV+SEKP GLKATSDE+DSVLNIARGK+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306

Query: 527 DGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSV 586
           DGEKTR VSSRKKPALKATSDEKDS   I REKKDGE SRTVSSQK PALKA  D+EDSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366

Query: 587 PNMATEKKDEQISGTVSSQKQPALK 611
            ++A E+KD + S TVSS++ P LK
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391



 Score =  428 bits (1101), Expect = e-120
 Identities = 245/385 (63%), Positives = 282/385 (73%)

Query: 159 TVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATE 218
           +VSSQKQPA K  SD  DS  N ATEIK+G   GTVSSQKQ A KAT+DE+ SVSNIATE
Sbjct: 7   SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66

Query: 219 IKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKED 278
           IK+G++SGTVS QK+ A K    +K S  NI      G  S TVSSQK PA KATS K D
Sbjct: 67  IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126

Query: 279 SVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPAL 338
           S LNIA E KDG +  TVS  + P LKAT DE+DS+ NIA   K+GEK+  VSS+K+PAL
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186

Query: 339 KATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTV 398
           KAT+DE+DS  NI    KDGE S  VSSQK P LK T+DEEDSV  IA E KDGEKS TV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246

Query: 399 SSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKK 458
           SS K P LKA+SDEKDS  NI R KK GE ++ V+S K   L+ATSDE+DS  NI R K+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306

Query: 459 DGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSV 518
           DGE +R+VSS+K PALK TSDE+DS   I RE KDGE SRTVSS+KPP LKATSDE+DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366

Query: 519 LNIARGKKDGEKTRTVSSRKKPALK 543
           L+IAR +KDGEK+RTVSS + P LK
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391



 Score =  391 bits (1005), Expect = e-108
 Identities = 230/385 (59%), Positives = 273/385 (70%)

Query: 261 TVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARG 320
           +VSSQK PA KATS  +DSV NIA E K+G  S TVS  + P  KAT DEKDS+ NIA  
Sbjct: 7   SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66

Query: 321 KKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEED 380
            K G+++  VS +K+ A K    +K S  NI      G  S  VSSQK P  K TSD+ D
Sbjct: 67  IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126

Query: 381 SVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSL 440
           S L IA E KDG +  TVSS+K P LKA++DE+DSV NIA   K GEK+  VSS+K+P+L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186

Query: 441 EATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTV 500
           +AT+DE+DS  NI  E KDGE S  VSSQK PALK T+DEEDSV  IA E KDGEKS TV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246

Query: 501 SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKK 560
           SS K P LKATSDEKDS  NI R KKDGE +RTV+S K   LKATSDE+DSVL IAR K+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306

Query: 561 DGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSV 620
           DGEK+R VSS+K+PALKA  D++DS  N+  EKKD + S TVSSQK PALKATSD++DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366

Query: 621 SNIPTEIKDGQQSGTVSSQKQPAWK 645
            +I  E KDG++S TVSS++ P  K
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391



 Score =  384 bits (987), Expect = e-106
 Identities = 229/387 (59%), Positives = 274/387 (70%)

Query: 295 TVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRG 354
           +VS  + P  KAT D+KDS+ NIA   K G  +  VSS+K+PA KATSDEKDS SNI   
Sbjct: 7   SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66

Query: 355 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 414
            K+G+ S  VS QK    K    ++ S+L IA     G KS TVSS+K P  KA+SD+ D
Sbjct: 67  IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126

Query: 415 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 474
           S LNIA   K G +   VSS+K+P+L+AT+DE+DS SNI  E KDGE S  VSSQK PAL
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186

Query: 475 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 534
           K T+DEEDSVL IA E KDGEKS TVSS+K P LKAT+DE+DSV  IA   KDGEK+ TV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246

Query: 535 SSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKK 594
           SSRKKPALKATSDEKDS   I REKKDGE SRTV+S+K   LKA  D+EDSV N+A  K+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306

Query: 595 DEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 654
           D + +  VSS+K+PALKATSD+KDS SNI  E KDG+ S TVSSQK PA KATS ++DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366

Query: 655 SNIATEIKDGQIRGTVSPQKQSAQKVI 681
            +IA E KDG+   TVS ++    KV+
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLKVM 393



 Score =  367 bits (943), Expect = e-101
 Identities = 217/374 (58%), Positives = 265/374 (70%)

Query: 330 VSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAREN 389
           VSS+K+PA KATSD+KDS SNI    K+G IS  VSSQK P  K TSDE+DSV  IA E 
Sbjct: 8   VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67

Query: 390 KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDS 449
           K+G++S TVS +K    K    +K S+LNIA     G K+  VSS+K+P+ +ATSD+ DS
Sbjct: 68  KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127

Query: 450 FSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 509
             NI  E KDG     VSSQK PALK T+DEEDSV  IA E KDGEKS TVSS+K P LK
Sbjct: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187

Query: 510 ATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVS 569
           AT+DE+DSVLNIA   KDGEK+ TVSS+K+PALKAT+DE+DSV  IA E KDGEKS TVS
Sbjct: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247

Query: 570 SQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKD 629
           S+K+PALKA  D++DS  N+  EKKD +IS TV+S+K   LKATSD++DSV NI    +D
Sbjct: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307

Query: 630 GQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLL 689
           G+++  VSS+K+PA KATS +KDS SNI  E KDG+   TVS QK  A K    ++ S+L
Sbjct: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367

Query: 690 NIATRITGGGKSGT 703
           +IA     G KS T
Sbjct: 368 SIAREEKDGEKSRT 381



 Score =  302 bits (774), Expect = 6e-82
 Identities = 180/305 (59%), Positives = 220/305 (72%)

Query: 397 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 456
           +VSS+K P  KA+SD+KDSV NIA   K G  +  VSS+K+P+ +ATSDEKDS SNI  E
Sbjct: 7   SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66

Query: 457 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 516
            K+G+ S  VS QK  A K    ++ S+L IA     G KS TVSS+K P  KATSD+ D
Sbjct: 67  IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126

Query: 517 SVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPAL 576
           S LNIA   KDG +  TVSS+K+PALKAT+DE+DSV  IA E KDGEKS TVSSQKQPAL
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186

Query: 577 KAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 636
           KA  D+EDSV N+ATE KD + S TVSSQKQPALKAT+D++DSVS I TEIKDG++SGTV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246

Query: 637 SSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRIT 696
           SS+K+PA KATS +KDS SNI  E KDG+I  TV+ +K +  K    ++ S+LNIA    
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306

Query: 697 GGGKS 701
            G K+
Sbjct: 307 DGEKT 311



 Score =  270 bits (690), Expect = 3e-72
 Identities = 157/251 (62%), Positives = 179/251 (71%), Gaps = 34/251 (13%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPA KAT+DE+DSVSNIATEIK+G++SGTVS QKQ A K    ++ S+LNIAT I
Sbjct: 144 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEI 203

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
             G KS TVSSQKQPA K  +D+ DS    ATEIKDG + GTVSS+K+ ALKAT+DE+ S
Sbjct: 204 KDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDS 263

Query: 212 VSNIATEIKDGEKSGTV----------------------------------SSQKKPALK 237
            SNI  E KDGE S TV                                  SS+KKPALK
Sbjct: 264 FSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALK 323

Query: 238 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 297
           ATSDEKDSFSNITREKKDGE SRTVSSQKPPALKATS +EDSVL+IARE+KDGEKSRTVS
Sbjct: 324 ATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVS 383

Query: 298 FDQPPGLKATR 308
            +QPPGLK  +
Sbjct: 384 SEQPPGLKVMK 394



 Score =  219 bits (559), Expect = 5e-57
 Identities = 130/205 (63%), Positives = 150/205 (73%)

Query: 499 TVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIARE 558
           +VSS+K P  KATSD+KDSV NIA   K+G  + TVSS+K+PA KATSDEKDSV  IA E
Sbjct: 7   SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66

Query: 559 KKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKD 618
            K+G++S TVS QKQ A K I  K+ S+ N+AT       SGTVSSQKQPA KATSDK D
Sbjct: 67  IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126

Query: 619 SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQ 678
           S  NI TEIKDG Q GTVSSQKQPA KAT+ ++DSVSNIATEIKDG+  GTVS QKQ A 
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186

Query: 679 KVIFKKKVSLLNIATRITGGGKSGT 703
           K    ++ S+LNIAT I  G KS T
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSET 211


>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
           polyclonal antibodies [Homo sapiens]
          Length = 868

 Score =  294 bits (752), Expect = 2e-79
 Identities = 163/205 (79%), Positives = 175/205 (85%)

Query: 499 TVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIARE 558
           +VSSEKP GLKATSDEKDSVLNIARGKK GEKTR VSS K+PALKATSD+++SV  +A E
Sbjct: 7   SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66

Query: 559 KKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKD 618
            KD + S TVSSQKQPALKA  DK+DSV N+ TE KD Q SGTVSSQKQPA KATS KKD
Sbjct: 67  TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126

Query: 619 SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQ 678
           SVSNI TEIKDGQ  GTVSSQ+QPA KAT  +KDSVSNIA EIKDG+  GTVSPQKQSAQ
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186

Query: 679 KVIFKKKVSLLNIATRITGGGKSGT 703
           KVIFKKKVSLLNIATRITGG KSGT
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGT 211



 Score =  256 bits (655), Expect = 4e-68
 Identities = 148/267 (55%), Positives = 185/267 (69%)

Query: 397 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 456
           +VSSEKP GLKA+SDEKDSVLNIARGKK+GEKT+RVSS K+P+L+ATSD+++S  N+  E
Sbjct: 7   SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66

Query: 457 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 516
            KD +IS  VSSQK PALK TSD++DSV  I  E KDG++S TVSS+K P  KATS +KD
Sbjct: 67  TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126

Query: 517 SVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPAL 576
           SV NIA   KDG+   TVSS+++PALKAT DEKDSV  IARE KDGEKS TVS QKQ A 
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186

Query: 577 KAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 636
           K I  K+ S+ N+AT       SGT   +  P LKAT + K+SV N  T++KD Q S   
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246

Query: 637 SSQKQPAWKATSVKKDSVSNIATEIKD 663
               + A +    + +   N   ++K+
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKN 273



 Score =  247 bits (630), Expect = 3e-65
 Identities = 141/230 (61%), Positives = 167/230 (72%)

Query: 466 VSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGK 525
           VSS+KP  LK TSDE+DSVL IAR  K GEK+R VSS K P LKATSD+++SV N+A   
Sbjct: 8   VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67

Query: 526 KDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDS 585
           KD + + TVSS+K+PALKATSD+KDSV  I  E KDG++S TVSSQKQPA KA   K+DS
Sbjct: 68  KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127

Query: 586 VPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWK 645
           V N+ATE KD QI GTVSSQ+QPALKAT D+KDSVSNI  EIKDG++SGTVS QKQ A K
Sbjct: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187

Query: 646 ATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRI 695
               KK S+ NIAT I  G   GT  P+     K   + K S+LN AT++
Sbjct: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKM 237



 Score =  231 bits (589), Expect = 2e-60
 Identities = 139/247 (56%), Positives = 169/247 (68%), Gaps = 3/247 (1%)

Query: 432 VSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIAREN 491
           VSS K   L+ATSDEKDS  NI R KK GE +R+VSS K PALK TSD+E+SV  +A E 
Sbjct: 8   VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67

Query: 492 KDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDS 551
           KD + S TVSS+K P LKATSD+KDSV NI    KDG+++ TVSS+K+PA KATS +KDS
Sbjct: 68  KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127

Query: 552 VLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALK 611
           V  IA E KDG+   TVSSQ+QPALKA  D++DSV N+A E KD + SGTVS QKQ A K
Sbjct: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187

Query: 612 ATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVS 671
               KK S+ NI T I  G +SGT   +  P  KAT   K+SV N AT++KD Q   T +
Sbjct: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQ---TST 244

Query: 672 PQKQSAQ 678
           P +Q  +
Sbjct: 245 PAEQDLE 251



 Score =  227 bits (579), Expect = 3e-59
 Identities = 144/301 (47%), Positives = 186/301 (61%), Gaps = 13/301 (4%)

Query: 295 TVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRG 354
           +VS ++P GLKAT DEKDS+LNIARGKK+GEKTRRVSS K+PALKATSD+++S  N+   
Sbjct: 7   SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66

Query: 355 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 414
            KD +IS  VSSQK P LK TSD++DSV  I  E KDG++S TVSS+K P  KA+S +KD
Sbjct: 67  TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126

Query: 415 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 474
           SV NIA   K G+    VSS+++P+L+AT DEKDS SNI RE KDGE S  VS QK  A 
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186

Query: 475 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 534
           K    ++ S+L IA     G KS T   E  P LKAT + K+SVLN A   KD +     
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQ----- 241

Query: 535 SSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKK 594
                    +T  E+D  +    E+K  E+      Q +  + +  D +D + +  T  +
Sbjct: 242 --------TSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSE 293

Query: 595 D 595
           D
Sbjct: 294 D 294



 Score =  221 bits (563), Expect = 2e-57
 Identities = 133/266 (50%), Positives = 171/266 (64%)

Query: 364 VSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGK 423
           VSS+KP  LK TSDE+DSVL IAR  K GEK+R VSS K P LKA+SD+++SV N+A   
Sbjct: 8   VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67

Query: 424 KYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDS 483
           K  + +  VSS+K+P+L+ATSD+KDS SNI  E KDG+ S  VSSQK PA K TS ++DS
Sbjct: 68  KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127

Query: 484 VLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALK 543
           V  IA E KDG+   TVSS++ P LKAT DEKDSV NIAR  KDGEK+ TVS +K+ A K
Sbjct: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187

Query: 544 ATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVS 603
               +K S+L IA     G KS T   +  P LKA  + ++SV N AT+ KD Q S    
Sbjct: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247

Query: 604 SQKQPALKATSDKKDSVSNIPTEIKD 629
              + A +    + +   N   ++K+
Sbjct: 248 QDLEMASEGEQKRLEEYENNQPQVKN 273



 Score =  220 bits (561), Expect = 3e-57
 Identities = 140/303 (46%), Positives = 181/303 (59%), Gaps = 17/303 (5%)

Query: 330 VSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAREN 389
           VSS K   LKATSDEKDS  NI RGKK GE +R+VSS K P LK TSD+E+SV  +A E 
Sbjct: 8   VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67

Query: 390 KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDS 449
           KD + S TVSS+K P LKA+SD+KDSV NI    K G+++  VSS+K+P+ +ATS +KDS
Sbjct: 68  KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127

Query: 450 FSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 509
            SNI  E KDG+I   VSSQ+ PALK T DE+DSV  IARE KDGEKS TVS +K    K
Sbjct: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187

Query: 510 ATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVS 569
               +K S+LNIA     G K+ T      P LKAT + K+SVL  A + KD + S    
Sbjct: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247

Query: 570 SQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQ--PALKATSDKKDSVSNIPTEI 627
              +               MA+E + +++    ++Q Q    + +  D  D + +  T  
Sbjct: 248 QDLE---------------MASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVS 292

Query: 628 KDG 630
           +DG
Sbjct: 293 EDG 295



 Score =  217 bits (552), Expect = 3e-56
 Identities = 134/261 (51%), Positives = 163/261 (62%)

Query: 90  YAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIAT 149
           +++S +K    KATSDEKDSV NIA   K G+++  VS  KQ A K    K+ S+ N+AT
Sbjct: 6   FSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMAT 65

Query: 150 RIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEE 209
                  SGTVSSQKQPA K  SDK DS  N  TEIKDG Q GTVSSQKQ A KAT+ ++
Sbjct: 66  ETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKK 125

Query: 210 GSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPA 269
            SVSNIATEIKDG+  GTVSSQ++PALKAT DEKDS SNI RE KDGE S TVS QK  A
Sbjct: 126 DSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSA 185

Query: 270 LKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRR 329
            K    K+ S+LNIA     G KS T   +  P LKAT + K+S+LN A   K+ + +  
Sbjct: 186 QKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTP 245

Query: 330 VSSRKKPALKATSDEKDSFSN 350
                + A +      + + N
Sbjct: 246 AEQDLEMASEGEQKRLEEYEN 266



 Score =  210 bits (535), Expect = 3e-54
 Identities = 129/237 (54%), Positives = 155/237 (65%)

Query: 159 TVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATE 218
           +VSS+K    K  SD+ DS LN A   K G +   VSS KQ ALKAT+D+E SV N+ATE
Sbjct: 7   SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66

Query: 219 IKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKED 278
            KD + SGTVSSQK+PALKATSD+KDS SNI  E KDG+ S TVSSQK PA KATSVK+D
Sbjct: 67  TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126

Query: 279 SVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPAL 338
           SV NIA E KDG+   TVS  + P LKAT DEKDS+ NIAR  K+GEK+  VS +K+ A 
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186

Query: 339 KATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKS 395
           K    +K S  NI      G  S     +  PTLK T + ++SVL  A + KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243



 Score =  210 bits (534), Expect = 4e-54
 Identities = 130/237 (54%), Positives = 153/237 (64%)

Query: 125 TVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATE 184
           +VS +K S  K    +K S+LNIA     G K+  VSS KQPA K  SDK +S  N ATE
Sbjct: 7   SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66

Query: 185 IKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKD 244
            KD    GTVSSQKQ ALKAT+D++ SVSNI TEIKDG++SGTVSSQK+PA KATS +KD
Sbjct: 67  TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126

Query: 245 SFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGL 304
           S SNI  E KDG+I  TVSSQ+ PALKAT  ++DSV NIARE KDGEKS TVS  +    
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186

Query: 305 KATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEIS 361
           K    +K SLLNIA     G K+        P LKAT + K+S  N     KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243



 Score =  207 bits (526), Expect = 4e-53
 Identities = 127/250 (50%), Positives = 157/250 (62%)

Query: 227 TVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIARE 286
           +VSS+K   LKATSDEKDS  NI R KK GE +R VSS K PALKATS KE+SV N+A E
Sbjct: 7   SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66

Query: 287 KKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKD 346
            KD + S TVS  + P LKAT D+KDS+ NI    K+G+++  VSS+K+PA KATS +KD
Sbjct: 67  TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126

Query: 347 SFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 406
           S SNI    KDG+I   VSSQ+ P LK T DE+DSV  IARE KDGEKS TVS +K    
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186

Query: 407 KASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV 466
           K    +K S+LNIA     G K+        P+L+AT + K+S  N   + KD + S   
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246

Query: 467 SSQKPPALKG 476
                 A +G
Sbjct: 247 EQDLEMASEG 256



 Score =  204 bits (518), Expect = 3e-52
 Identities = 133/292 (45%), Positives = 174/292 (59%)

Query: 193 TVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITRE 252
           +VSS+K   LKAT+DE+ SV NIA   K GEK+  VSS K+PALKATSD+++S  N+  E
Sbjct: 7   SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66

Query: 253 KKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKD 312
            KD +IS TVSSQK PALKATS K+DSV NI  E KDG++S TVS  + P  KAT  +KD
Sbjct: 67  TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126

Query: 313 SLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 372
           S+ NIA   K+G+    VSS+++PALKAT DEKDS SNI R  KDGE S  VS QK    
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186

Query: 373 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRV 432
           K    ++ S+L IA     G KS T   E  P LKA+ + K+SVLN A   K  + +   
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246

Query: 433 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 484
               + + E      + + N   + K+   SR        + +  S++ DS+
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 298



 Score =  193 bits (491), Expect = 4e-49
 Identities = 118/237 (49%), Positives = 154/237 (64%)

Query: 261 TVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARG 320
           +VSS+KP  LKATS ++DSVLNIAR KK GEK+R VS  + P LKAT D+++S+ N+A  
Sbjct: 7   SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66

Query: 321 KKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEED 380
            K+ + +  VSS+K+PALKATSD+KDS SNI    KDG+ S  VSSQK P  K TS ++D
Sbjct: 67  TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126

Query: 381 SVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSL 440
           SV  IA E KDG+   TVSS++ P LKA+ DEKDSV NIAR  K GEK+  VS +K+ + 
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186

Query: 441 EATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKS 497
           +    +K S  NI      G  S     +  P LK T + ++SVL  A + KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243



 Score =  165 bits (417), Expect = 2e-40
 Identities = 162/535 (30%), Positives = 240/535 (44%), Gaps = 48/535 (8%)

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
           +S QKQPA KATSD+KDSVSNI TEIK+GQQSGTVS QKQ A K    KK S+ NIAT I
Sbjct: 76  VSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEI 135

Query: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
             G   GTVSSQ+QPA K   D+ DS  N A EIKDG + GTVS QKQ A K    ++ S
Sbjct: 136 KDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVS 195

Query: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
           + NIAT I  G KSGT   +  P LKAT + K+S  N   + KD + S         A +
Sbjct: 196 LLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASE 255

Query: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSL--------LNIARGKKN 323
               + +   N   + K+   SR    D     +   ++ DSL        L I + +  
Sbjct: 256 GEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMK 315

Query: 324 GEKTRRVSSRKKP--ALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDS 381
            +    +   KK     K  ++ KD+     R K      RK+ ++     K  S++E+ 
Sbjct: 316 CKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVK-----IRKLKNKASVLQKRLSEKEEI 370

Query: 382 VLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLE 441
              +  E  + EK      E      A   EK    N+       E  ++V  + + + E
Sbjct: 371 KSQLKHETLELEK------ELCSLRFAIQQEKKKRRNVE------ELHQKVREKLRITEE 418

Query: 442 ATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV---------LGIARENK 492
               E D    I    K  E+  K        +  T ++ED +         +   R  K
Sbjct: 419 QYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEK 478

Query: 493 DGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKT--RTVSSRKKPALKATSDEKD 550
           D  K++ +  +    LK     K    ++ +  K  E+T   T++         T +   
Sbjct: 479 DTIKNQNLEKKY---LKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTT 535

Query: 551 SVLYIAREKKDGEKSRT-VSSQKQPALKAICDKEDSVPNMATEKKDEQIS--GTV 602
               + ++++ G++  T + S +     A+CD + S     + K+D++++  GTV
Sbjct: 536 LRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQS----HSSKRDQELAFQGTV 586


>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 753

 Score =  197 bits (500), Expect = 4e-50
 Identities = 129/257 (50%), Positives = 150/257 (58%), Gaps = 39/257 (15%)

Query: 18  EYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDV 77
           EYQPLL AVSRRKVKMVEFLLKKKANVNAIDYLGRSALI AVTLGEKDIVILLLQHNIDV
Sbjct: 485 EYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDV 544

Query: 78  FSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVI 137
            SRD + K+A DYA+  + +            + ++  E K                   
Sbjct: 545 LSRDAFRKIAGDYAIEAKNRV-----------IFDLIYEYK------------------- 574

Query: 138 FKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQ 197
            +K+   L I         S  VSSQKQPA K  S K DS  N ATEIKDG + GTVSSQ
Sbjct: 575 -RKRYEDLPI--------NSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQ 625

Query: 198 KQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGE 257
           KQ ALK T+D++ SVSN ATEIKD +KSGTV    +  L  +    D+ +    E +   
Sbjct: 626 KQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSL 685

Query: 258 ISRTVSSQKPPALKATS 274
            S  +S    P  K  S
Sbjct: 686 ESEIISKLYIPKRKIIS 702



 Score =  107 bits (266), Expect = 5e-23
 Identities = 95/290 (32%), Positives = 136/290 (46%), Gaps = 33/290 (11%)

Query: 21  PLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQH--NIDVF 78
           PL+ AV  R+      LL+  AN N  D+ GR+AL  AV   +  ++  LL H  NI+  
Sbjct: 422 PLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEEC 481

Query: 79  SRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIF 138
           S+  Y  L   +A+S +K    +    +K +V N    +        V+  ++    ++ 
Sbjct: 482 SKCEYQPLL--FAVSRRKVKMVEFLLKKKANV-NAIDYLGRSALIHAVTLGEKDIVILLL 538

Query: 139 KKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTAT-----EIKDG----- 188
           +  + +L+                 +    K A D    A N        E K       
Sbjct: 539 QHNIDVLS-----------------RDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDL 581

Query: 189 -LQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFS 247
            +    VSSQKQ ALKAT+ +E S+SNIATEIKDG+KSGTVSSQK+PALK TSD+ DS S
Sbjct: 582 PINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVS 641

Query: 248 NITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 297
           N   E KD + S TV       L  +  + D+V     E +   +S  +S
Sbjct: 642 NTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIIS 691



 Score =  107 bits (266), Expect = 5e-23
 Identities = 58/74 (78%), Positives = 61/74 (82%)

Query: 599 SGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIA 658
           S  VSSQKQPALKATS K+DS+SNI TEIKDGQ+SGTVSSQKQPA K TS K DSVSN A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644

Query: 659 TEIKDGQIRGTVSP 672
           TEIKD Q  GTV P
Sbjct: 645 TEIKDEQKSGTVLP 658



 Score =  105 bits (261), Expect = 2e-22
 Identities = 59/96 (61%), Positives = 67/96 (69%)

Query: 565 SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP 624
           S  VSSQKQPALKA   KEDS+ N+ATE KD Q SGTVSSQKQPALK TSDK DSVSN  
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644

Query: 625 TEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATE 660
           TEIKD Q+SGTV    +     +  + D+V+   TE
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 680



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 60/130 (46%), Positives = 82/130 (63%), Gaps = 2/130 (1%)

Query: 534 VSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEK 593
           VSS+K+PALKATS ++DS+  IA E KDG+KS TVSSQKQPALK   DK+DSV N ATE 
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647

Query: 594 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 653
           KDEQ SGTV    +  L  +  + D+V+   TE +   +S  +S    P  K  S +  S
Sbjct: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR--S 705

Query: 654 VSNIATEIKD 663
           + ++   +++
Sbjct: 706 IKDVLPPVEE 715



 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 53/120 (44%), Positives = 69/120 (57%)

Query: 497 SRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIA 556
           S  VSS+K P LKATS ++DS+ NIA   KDG+K+ TVSS+K+PALK TSD+ DSV   A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644

Query: 557 REKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDK 616
            E KD +KS TV    +  L     + D+V    TE +    S  +S    P  K  S +
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704



 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 53/117 (45%), Positives = 66/117 (56%)

Query: 463 SRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIA 522
           S  VSSQK PALK TS +EDS+  IA E KDG+KS TVSS+K P LK TSD+ DSV N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644

Query: 523 RGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAI 579
              KD +K+ TV    +  L  +    D+V     E +   +S  +S    P  K I
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKII 701



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 46/71 (64%), Positives = 49/71 (69%)

Query: 633 SGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIA 692
           S  VSSQKQPA KATS K+DS+SNIATEIKDGQ  GTVS QKQ A K    K  S+ N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644

Query: 693 TRITGGGKSGT 703
           T I    KSGT
Sbjct: 645 TEIKDEQKSGT 655



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 42/69 (60%), Positives = 52/69 (75%)

Query: 432 VSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIAREN 491
           VSS+K+P+L+ATS ++DS SNI  E KDG+ S  VSSQK PALK TSD++DSV   A E 
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647

Query: 492 KDGEKSRTV 500
           KD +KS TV
Sbjct: 648 KDEQKSGTV 656



 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 49/115 (42%), Positives = 65/115 (56%)

Query: 330 VSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAREN 389
           VSS+K+PALKATS ++DS SNI    KDG+ S  VSSQK P LK TSD++DSV   A E 
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647

Query: 390 KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATS 444
           KD +KS TV       L  S    D+V       ++  +++ +S    P  +  S
Sbjct: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 41/72 (56%), Positives = 49/72 (68%)

Query: 259 SRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIA 318
           S  VSSQK PALKATS KEDS+ NIA E KDG+KS TVS  + P LK T D+ DS+ N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644

Query: 319 RGKKNGEKTRRV 330
              K+ +K+  V
Sbjct: 645 TEIKDEQKSGTV 656



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 47/115 (40%), Positives = 61/115 (53%)

Query: 361 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA 420
           S  VSSQK P LK TS +EDS+  IA E KDG+KS TVSS+K P LK +SD+ DSV N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644

Query: 421 RGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALK 475
              K  +K+  V    +  L  +    D+ +    E +    S  +S    P  K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 46/118 (38%), Positives = 64/118 (54%)

Query: 395 SRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNIT 454
           S  VSS+K P LKA+S ++DS+ NIA   K G+K+  VSS+K+P+L+ TSD+ DS SN  
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644

Query: 455 REKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATS 512
            E KD + S  V       L  +    D+V     EN+   +S  +S    P  K  S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 45/118 (38%), Positives = 61/118 (51%)

Query: 293 SRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNIT 352
           S  VS  + P LKAT  ++DS+ NIA   K+G+K+  VSS+K+PALK TSD+ DS SN  
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644

Query: 353 RGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASS 410
              KD + S  V       L  +    D+V     EN+   +S  +S    P  K  S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702


>gi|239748832 PREDICTED: hypothetical protein XP_002346815 [Homo
           sapiens]
          Length = 199

 Score =  125 bits (314), Expect = 1e-28
 Identities = 64/84 (76%), Positives = 71/84 (84%)

Query: 18  EYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDV 77
           EYQPLLLAVS+RK+KMVE LLKK  NVNAIDYL RSALILAV LGEKDIV+LLLQHN DV
Sbjct: 108 EYQPLLLAVSQRKLKMVEVLLKKNTNVNAIDYLSRSALILAVNLGEKDIVVLLLQHNTDV 167

Query: 78  FSRDVYGKLAEDYAMSPQKQPAEK 101
           FSRD YGK AEDYA+  + +  +K
Sbjct: 168 FSRDAYGKTAEDYAIEAKNKIFKK 191


>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
          Length = 1341

 Score =  108 bits (271), Expect = 1e-23
 Identities = 169/692 (24%), Positives = 288/692 (41%), Gaps = 71/692 (10%)

Query: 4   HGVSLLGYNVQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGE 63
           HG  +  +N   L    PLLL++++R  ++VEFLL K AN NA++    +AL+LAV  G 
Sbjct: 105 HGAVIEVHNKASLT---PLLLSITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGS 161

Query: 64  KDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVS-NIATEIKEGQQ 122
            +IV +LLQ N+DVF+ D+ G  AE YA++       +   +    +S N      EG  
Sbjct: 162 SEIVGMLLQQNVDVFAADICGVTAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTS 221

Query: 123 SGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKT-DSALNT 181
           +GT       A++     + SL+          ++  +  +    +++  +KT D A + 
Sbjct: 222 AGTPDEAAPLAERTPDTAE-SLVEKTP-----DEAAPLVERTPDTAESLVEKTPDEAASL 275

Query: 182 ATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSD 241
                D +QC     +K  + K     E +   I +  K+  +  T  ++ +P   A   
Sbjct: 276 VEGTSDKIQC----LEKATSGKFEQSAEETPREITSPAKETSEKFTWPAKGRPRKIAWEK 331

Query: 242 EKDSFSNITREKKDGEISRTVSSQKPP-----ALKATSVKEDSVLNIAREK-KDGEKSRT 295
           ++D+   I    K+     T +++  P       K T VK   V  +   K K  EK R+
Sbjct: 332 KEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVARVTSNKTKVLEKGRS 391

Query: 296 VSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGK 355
                P    +T+   +     +  K+  ++     SR   +L  +S +       +  +
Sbjct: 392 KMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSR---SLFESSAKIQVCIPESIYQ 448

Query: 356 KDGEISRKVSS--QKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEK 413
           K  EI+R+V    +KP   K   + ++SV   A E K+ +  R       P     S +K
Sbjct: 449 KVMEINREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRA-----DPMFPPESKQK 503

Query: 414 DSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKD-SFSNITREKKDGEISRKV--SSQK 470
           D          Y E     +S    SL  T  +KD      T +K+  +I+ K+  S  K
Sbjct: 504 D----------YEE-----NSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNK 548

Query: 471 PPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEK 530
              LK T   + S+   A E KD +  +     KP   +  ++ + SV N A   K+ + 
Sbjct: 549 DGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQT 608

Query: 531 TRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMA 590
            R                 D +L    ++KD E++   S   +   + +  K+  +P  A
Sbjct: 609 LRA----------------DEILPSESKQKDYEEN---SWDTESLCETVSQKDVCLPKAA 649

Query: 591 TEKKDEQISGTV--SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATS 648
            +K+ ++I+G +  S  K   LKA    K S+     E+ D Q       +K  A++   
Sbjct: 650 HQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI 709

Query: 649 VKKDSVSNIATEIKDGQ-IRGTVSPQKQSAQK 679
             + SV N A E+K+ Q +R       +S QK
Sbjct: 710 EMQKSVPNKALELKNEQTLRADEILPSESKQK 741



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 140/593 (23%), Positives = 225/593 (37%), Gaps = 108/593 (18%)

Query: 93  SPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIM 152
           SP K+ +EK T   K     IA E KE      +SP K++++K  +  K           
Sbjct: 307 SPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAK----------- 355

Query: 153 GGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSV 212
             G+   ++ +K+                 T +K G     V+S K + L     E+G  
Sbjct: 356 --GRPRKIAWEKKE----------------TPVKTGC-VARVTSNKTKVL-----EKGRS 391

Query: 213 SNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITRE-----------------KKD 255
             IA   K+     + + Q+ P+ ++  +E + +S  +R                  +K 
Sbjct: 392 KMIACPTKESSTKASANDQRFPS-ESKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKV 450

Query: 256 GEISRTVSS--QKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDS 313
            EI+R V    +KP A K     ++SV N A E K+ +  R      PP  K    E++S
Sbjct: 451 MEINREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPMF-PPESKQKDYEENS 509

Query: 314 LLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLK 373
                    + E      S+K   L   + +K+        K +G++    S  K   LK
Sbjct: 510 W--------DSESLCETVSQKDVCLPKATHQKEI------DKINGKLEE--SPNKDGLLK 553

Query: 374 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVS 433
            T   + S+   A E KD +  +     KP   + +++ + SV N A   K  E+T R  
Sbjct: 554 ATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELK-NEQTLRAD 612

Query: 434 ------SRKKP---------SLEATSDEKD-SFSNITREKKDGEISRKV--SSQKPPALK 475
                 S++K          SL  T  +KD        +K+  +I+ K+  S  K   LK
Sbjct: 613 EILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLK 672

Query: 476 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRT-- 533
                + S+   A E  D +  +    EKP   +   + + SV N A   K+ +  R   
Sbjct: 673 ANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADE 732

Query: 534 ------------VSSRKKPALKATSDEKDSVLYIAREKKDGEKSR---TVSSQKQPALKA 578
                        SS    +L  T  +KD  L  A  +K+ +K       S      LKA
Sbjct: 733 ILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKA 792

Query: 579 ICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 631
            C  + S+P  A E  D Q       +K  A +   + + SV N   E+K+ Q
Sbjct: 793 PCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQ 845



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 90/365 (24%), Positives = 138/365 (37%), Gaps = 57/365 (15%)

Query: 363 KVSSQKPPTLKGTSDE----EDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLN 418
           K   +    ++GTSD+    E +  G   ++ +       S  K    K +   K     
Sbjct: 267 KTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPREITSPAKETSEKFTWPAKGRPRK 326

Query: 419 IARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKD-----GEISRKVSSQKPPA 473
           IA  KK     + +S  K+ S + T   K     I  EKK+     G ++R  S++    
Sbjct: 327 IAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVARVTSNKTKVL 386

Query: 474 LKGTSDEEDSVLGIARENKDGEKSRTVSSEK-PPGLKATSDEKDSVLNIARGKKDGEKTR 532
            KG S        IA   K+     + + ++ P   K   DE+ S         D     
Sbjct: 387 EKGRSKM------IACPTKESSTKASANDQRFPSESKQEEDEEYSC--------DSRSLF 432

Query: 533 TVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATE 592
             S++ +  +  +  +K  V+ I RE ++  K       K  A K   + ++SVPN A E
Sbjct: 433 ESSAKIQVCIPESIYQK--VMEINREVEEPPK-------KPSAFKPAIEMQNSVPNKAFE 483

Query: 593 KKDEQ------ISGTVSSQKQ--------PALKATSDKKDSVSNIPTEIKDGQQ-SGTV- 636
            K+EQ      +    S QK          +L  T  +KD      T  K+  + +G + 
Sbjct: 484 LKNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLE 543

Query: 637 -SSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSA-------QKVIFKKKVSL 688
            S  K    KAT   K S+   A E+KD Q      P K SA       QK +  K + L
Sbjct: 544 ESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALEL 603

Query: 689 LNIAT 693
            N  T
Sbjct: 604 KNEQT 608



 Score = 37.4 bits (85), Expect = 0.048
 Identities = 66/292 (22%), Positives = 115/292 (39%), Gaps = 36/292 (12%)

Query: 57  LAVTLGEKDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATE 116
           L  T+ +KD+ +    H  ++    + GKL      SP K    KA    K S+   A E
Sbjct: 634 LCETVSQKDVCLPKAAHQKEIDK--INGKLEG----SPVKDGLLKANCGMKVSIPTKALE 687

Query: 117 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 176
           + + Q      P+K SA +   + + S+ N A  +    +    + +  P+     D  +
Sbjct: 688 LMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKN--EQTLRADEILPSESKQKDYEE 745

Query: 177 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPAL 236
           S+ ++ +       C TVS +     KAT  +E  +  I  ++++       S      L
Sbjct: 746 SSWDSES------LCETVSQKDVCLPKATHQKE--IDKINGKLEE-------SPDNDGFL 790

Query: 237 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTV 296
           KA    K S      E  D +  +    +KP A +     + SV N A E K+    +T+
Sbjct: 791 KAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKN---EQTL 847

Query: 297 SFDQ--PPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKD 346
             DQ  P   K  + E++S         + E  R   S+K   +   + +K+
Sbjct: 848 RADQMFPSESKQKKVEENSW--------DSESLRETVSQKDVCVPKATHQKE 891


>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
          Length = 1392

 Score =  102 bits (253), Expect = 2e-21
 Identities = 170/694 (24%), Positives = 267/694 (38%), Gaps = 132/694 (19%)

Query: 7   SLLGYN----VQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLG 62
           +LL Y     VQ      PLLLA+ +R  + VEFLL K AN NA +    +AL+LA+  G
Sbjct: 157 TLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICEG 216

Query: 63  EKDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQ 122
             +IV +LLQ N+DVF+ D++G  AE YA +                V+ I  ++ E  +
Sbjct: 217 SSEIVGMLLQQNVDVFAEDIHGITAERYAAA--------------CGVNYIHQQLLEHIR 262

Query: 123 SGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTA 182
               +PQ  + +                    G S     +  P ++   D  +S L   
Sbjct: 263 KLPKNPQNTNPE--------------------GTSTGTPDEAAPLAERTPDTAESLLEKT 302

Query: 183 TEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDE 242
            +    L  GT  S K Q L   T               G+   +     +  L+ T + 
Sbjct: 303 PDEAARLVEGT--SAKIQCLGKAT--------------SGKFEQSTEETPRKILRPTKET 346

Query: 243 KDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPP 302
            + FS   +E+     SR ++ ++    K TSVK + V  +   K +  +  T +    P
Sbjct: 347 SEKFSWPAKER-----SRKITWEE----KETSVKTECVAGVTPNKTEVLEKGTSNMIACP 397

Query: 303 GLKATRDEKDSLLNIA-----------RGKKNGEKTR---RVSSRKKPALKATSDEKDSF 348
             K T  +  + ++++           R  +N + T+     +   K   K+ +      
Sbjct: 398 -TKETSTKASTNVDVSSVEPIFSLFGTRTIENSQCTKVEEDFNLATKIISKSAAQNYTCL 456

Query: 349 SNITRGKKDGEISRKVSSQK-PPTLKGTSDEEDS---------------VLGIARENKDG 392
            + T  K    I+ K+  Q  P   K   DEE S                +  +   K  
Sbjct: 457 PDATYQKDIKTINHKIEDQMFPSESKREEDEEYSWDSGSLFESSAKTQVCIPESMYQKVM 516

Query: 393 EKSRTVSS--EKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSF 450
           E +R V    EKP   K + + + +V N A   K  E+T R +       +   DE++S+
Sbjct: 517 EINREVEELPEKPSAFKPAVEMQKTVPNKAFELK-NEQTLRAAQMFPSESKQKDDEENSW 575

Query: 451 SN----------------ITREKKDGEISRKV--SSQKPPALKGTSDEEDSVLGIARENK 492
            +                 T +K+   +S K+  S  K   LK T   + S+   A E K
Sbjct: 576 DSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSLPNKALELK 635

Query: 493 DGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSV 552
           D E  +  S +K   LK T   K S+ N A   KD E  +  S      LK T   K S+
Sbjct: 636 DRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKPTCGRKVSL 695

Query: 553 LYIAREKKDGEKSRTV------SSQK---------QPALKAICDKEDSVPNMATEKKDEQ 597
              A E KD E  +        S QK         +  L+ +   +  +P    +K+ + 
Sbjct: 696 PNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLPKATHQKEFDT 755

Query: 598 ISGTV--SSQKQPALKATSDKKDSVSNIPTEIKD 629
           +SG +  S  K   LK T   K S+ N   E+KD
Sbjct: 756 LSGKLEESPDKDGLLKPTCGMKISLPNKALELKD 789



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 161/709 (22%), Positives = 265/709 (37%), Gaps = 138/709 (19%)

Query: 32  KMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRDVYGKLAEDYA 91
           ++V FL+ +K  +N +D  GR+ L+ A+    +    +L+    D+   DVYG  A  YA
Sbjct: 87  EVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTALHYA 146

Query: 92  MSPQKQPAEKATSDEKDSVSNIATEIKEG-----QQSGTVSP-----QKQSAQKVIF--- 138
           +               +++  +AT +  G     Q   +++P     QK+S Q V F   
Sbjct: 147 VY-------------SENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLT 193

Query: 139 ---------KKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGL 189
                    + K + L +A  I  G         +Q     A D     ++  T  +   
Sbjct: 194 KNANANAFNESKCTALMLA--ICEGSSEIVGMLLQQNVDVFAED-----IHGITAERYAA 246

Query: 190 QCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNI 249
            CG V+   QQ L+       +  N   E   G  +GT   +  P  + T D  +S    
Sbjct: 247 ACG-VNYIHQQLLEHIRKLPKNPQNTNPE---GTSTGT-PDEAAPLAERTPDTAESLL-- 299

Query: 250 TREKKDGEISRTV--SSQKPPAL-KATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKA 306
             EK   E +R V  +S K   L KATS K         E+   E  R +       L+ 
Sbjct: 300 --EKTPDEAARLVEGTSAKIQCLGKATSGKF--------EQSTEETPRKI-------LRP 342

Query: 307 TRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSS 366
           T++  +     A+     E++R+++  +K     TS + +  + +T  K +  + +  S+
Sbjct: 343 TKETSEKFSWPAK-----ERSRKITWEEKE----TSVKTECVAGVTPNKTE-VLEKGTSN 392

Query: 367 QKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYG 426
                 K TS +  + + ++          T + E     K   D      N+A      
Sbjct: 393 MIACPTKETSTKASTNVDVSSVEPIFSLFGTRTIENSQCTKVEED-----FNLA------ 441

Query: 427 EKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQK-PPALKGTSDEEDS-- 483
             TK +S     +     D        T +K    I+ K+  Q  P   K   DEE S  
Sbjct: 442 --TKIISKSAAQNYTCLPDA-------TYQKDIKTINHKIEDQMFPSESKREEDEEYSWD 492

Query: 484 -------------VLGIARENKDGEKSRTVSS--EKPPGLKATSDEKDSVLNIARGKKDG 528
                         +  +   K  E +R V    EKP   K   + + +V N A   K+ 
Sbjct: 493 SGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPNKAFELKNE 552

Query: 529 EKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPN 588
           +  R        A    S+ K         +KD E++   S   +   + +  K+  +P 
Sbjct: 553 QTLRA-------AQMFPSESK---------QKDDEEN---SWDSESPCETVSQKDVYLPK 593

Query: 589 MATEKKDEQISGTV--SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKA 646
              +K+ + +SG +  S  K   LK T  +K S+ N   E+KD +     S  K    K 
Sbjct: 594 ATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKP 653

Query: 647 TSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRI 695
           T  +K S+ N A E+KD +     SP      K    +KVSL N A  +
Sbjct: 654 TCGRKVSLPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALEL 702



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 108/447 (24%), Positives = 166/447 (37%), Gaps = 66/447 (14%)

Query: 94  PQKQPAEKATSDEKDSVSNIATEIKE------GQQSGTVSPQK---------QSAQKVIF 138
           P+K  A K   + + +V N A E+K        Q   + S QK         +S  + + 
Sbjct: 526 PEKPSAFKPAVEMQKTVPNKAFELKNEQTLRAAQMFPSESKQKDDEENSWDSESPCETVS 585

Query: 139 KKKVSLLNIATRIMGGGKSGTV--SSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSS 196
           +K V L     +      SG +  S  K    K    +  S  N A E+KD       S 
Sbjct: 586 QKDVYLPKATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESP 645

Query: 197 QKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDG 256
            K   LK T   + S+ N A E+KD E     S      LK T   K S  N   E KD 
Sbjct: 646 DKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDR 705

Query: 257 EISRTV------SSQKP--------PALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPP 302
           E  +        S QK          +   T ++ D  L  A  +K+        FD   
Sbjct: 706 ETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLPKATHQKE--------FDTLS 757

Query: 303 GLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKA--TSDEKDSFSNITRGKKDGEI 360
           G      +KD LL    G K     + +  + +   KA   S  + +FS   +   +   
Sbjct: 758 GKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQ 817

Query: 361 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDG-EKSRTVSSEKPPGL--KASSDEKDSVL 417
           S KV             EED  L      K+G  K+ T   E+  G+  +A  D+ + + 
Sbjct: 818 STKV-------------EEDFNL----TTKEGATKTVTGQQERDIGIIERAPQDQTNKMP 860

Query: 418 NIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV--SSQKPPALK 475
               G+K  E TK  S  +  S+  T +  +     T +K+    + K+  S +KP   +
Sbjct: 861 TSELGRK--EDTKSTSDSEIISVSDTQN-YECLPEATYQKEIKTTNGKIEESPEKPSHFE 917

Query: 476 GTSDEEDSVLGIARENKDGEKSRTVSS 502
             ++ ++SV     E K+ +  R  S+
Sbjct: 918 PATEMQNSVPNKGLEWKNKQTLRADST 944



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 137/565 (24%), Positives = 214/565 (37%), Gaps = 82/565 (14%)

Query: 58  AVTLGEK--DIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIAT 115
           A  L E+  D    LL+   D  +R V G  A+   +   K  + K     +++   I  
Sbjct: 284 AAPLAERTPDTAESLLEKTPDEAARLVEGTSAKIQCLG--KATSGKFEQSTEETPRKILR 341

Query: 116 EIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIA---------TRIMGGGKSGTVSSQKQP 166
             KE  +  +  P K+ ++K+ +++K + +            T ++  G S  ++   + 
Sbjct: 342 PTKETSEKFSW-PAKERSRKITWEEKETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKE 400

Query: 167 ASKTASDKTD-SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEI--KDGE 223
            S  AS   D S++     +      GT + +  Q  K   D      N+AT+I  K   
Sbjct: 401 TSTKASTNVDVSSVEPIFSL-----FGTRTIENSQCTKVEED-----FNLATKIISKSAA 450

Query: 224 KSGT----VSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDS 279
           ++ T     + QK         E   F + ++ ++D E S    S     L  +S K   
Sbjct: 451 QNYTCLPDATYQKDIKTINHKIEDQMFPSESKREEDEEYSWDSGS-----LFESSAKTQV 505

Query: 280 VLNIAREKKDGEKSRTVSF--DQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPA 337
            +  +  +K  E +R V    ++P   K   + + ++ N A   KN E+T R +      
Sbjct: 506 CIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPNKAFELKN-EQTLRAAQMFPSE 564

Query: 338 LKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL-KGTSDEE-DSVLGIAREN--KDGE 393
            K   DE++S+        D E   +  SQK   L K T  +E D++ G   E+  KDG 
Sbjct: 565 SKQKDDEENSW--------DSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGL 616

Query: 394 KSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNI 453
                       LK +   K S+ N A   K  E  K  S  K   L+ T   K S  N 
Sbjct: 617 ------------LKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNK 664

Query: 454 TREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSD 513
             E KD E  +  S      LK T   + S+   A E KD E  +      P   K   D
Sbjct: 665 ALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMF-PSESKQKDD 723

Query: 514 EKDSVLNIARGKKDGEKTRTVSSRKKPAL-KATSDEKDSVLYIAREKKDGEKSRTVSSQK 572
           E++S         D E       +    L KAT  ++   L    E+         S  K
Sbjct: 724 EENSW--------DFESFLETLLQNDVCLPKATHQKEFDTLSGKLEE---------SPDK 766

Query: 573 QPALKAICDKEDSVPNMATEKKDEQ 597
              LK  C  + S+PN A E KD +
Sbjct: 767 DGLLKPTCGMKISLPNKALELKDRE 791



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 103/444 (23%), Positives = 176/444 (39%), Gaps = 57/444 (12%)

Query: 60   TLGEKDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKE 119
            T+ +KD+ +    H  +  +  + GKL E    SP K    K T   K S+ N A E+K+
Sbjct: 583  TVSQKDVYLPKATHQKEFDT--LSGKLEE----SPVKDGLLKPTCGRKVSLPNKALELKD 636

Query: 120  GQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSAL 179
             +     SP K    K    +KVSL N A  +         S       K    +  S  
Sbjct: 637  RETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLP 696

Query: 180  NTATEIKD-----GLQCGTVSSQKQQALKATTDEEGSVSNI---------ATEIKDGEK- 224
            N A E+KD       Q     S+++   + + D E  +  +         AT  K+ +  
Sbjct: 697  NKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLPKATHQKEFDTL 756

Query: 225  SGTV--SSQKKPALKATSDEKDSFSNITREKKDGEI--SRTVSS--------QKPPALKA 272
            SG +  S  K   LK T   K S  N   E KD E   +  VSS         KP    +
Sbjct: 757  SGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVSSVESTFSLFGKPTTENS 816

Query: 273  TSVKEDSVLNIAREKKDGEKSRTVSFDQPPGL--KATRDEKDSLLNIARGKKNGEKTRRV 330
             S K +   N+   K+   K+ T   ++  G+  +A +D+ + +     G+K  E T+  
Sbjct: 817  QSTKVEEDFNLT-TKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRK--EDTKST 873

Query: 331  SSRKKPALKATSDEKDSFSNITRGKKDGEISRKV--SSQKPPTLKGTSDEEDSVLGIARE 388
            S  +  ++  T +  +     T  K+    + K+  S +KP   +  ++ ++SV     E
Sbjct: 874  SDSEIISVSDTQN-YECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNKGLE 932

Query: 389  NKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRK-KPSLEATSDEK 447
             K+ +            L+A S     +L+     + G + K+ +  +    +E T   K
Sbjct: 933  WKNKQT-----------LRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQT---K 978

Query: 448  DSFSNITREKKDG-EISRKVSSQK 470
            + F  + +E  +  EI  ++ +QK
Sbjct: 979  NKFCVLQKELSEAKEIKSQLENQK 1002


>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
           sapiens]
          Length = 498

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 55/104 (52%), Positives = 73/104 (70%), Gaps = 2/104 (1%)

Query: 8   LLGYNVQILNE--YQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N+    PLLLAV  +K +MV+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 186 LYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRFGRTALILAVRCGSAS 245

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDS 109
           IV LLLQ NIDVFS+DV+G+ AEDYA+S       +  SD K++
Sbjct: 246 IVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLLSDYKEN 289



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 39/141 (27%), Positives = 63/141 (44%), Gaps = 13/141 (9%)

Query: 10  GYNVQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVIL 69
           G N +   +   L LA +    ++V  LL ++  ++  D   R+ALI AV   E +  ++
Sbjct: 91  GINKRDKKKRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALM 150

Query: 70  LLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSG----- 124
           LLQH  D    D+YG  A  YA+  + +   K       ++     +I+   + G     
Sbjct: 151 LLQHGTDPNLPDMYGNTALHYAVYNEDKLMAK-------TLLLYGADIESKNKGGLTPLL 203

Query: 125 -TVSPQKQSAQKVIFKKKVSL 144
             V  QKQ   K + KKK +L
Sbjct: 204 LAVHGQKQRMVKFLIKKKANL 224


>gi|134133226 protein expressed in prostate, ovary, testis, and
           placenta 2 [Homo sapiens]
          Length = 1075

 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 89/293 (30%), Positives = 134/293 (45%), Gaps = 50/293 (17%)

Query: 8   LLGYNVQILNEY--QPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N++   PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSV--------SNIATEI 117
           IV LLL+ NIDV S+D+ G+ A +YA+S       +  SD K+          SN   E+
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQEL 379

Query: 118 K-----EGQQ---SGTVSPQKQSAQKVIFK---------------KKVSLLNIATR--IM 152
           K     E Q+   S    P+K S +  I K                 V LL   T     
Sbjct: 380 KLTSEEESQRFKGSENSQPEKMSQELEINKDGDREVEEEMKKHESNNVGLLENLTNGVTA 439

Query: 153 GGGKSGTVSSQKQ--PASKTASDKTDSALNTATEI------KDGLQCGTVSSQKQQALKA 204
           G G +G +  +K   P ++   D      +   E+      K   +  + +S  +Q LK 
Sbjct: 440 GNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKL 499

Query: 205 TTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSD-EKDSFSNITREKKDG 256
           T++EE      +  +K  E        ++P +    D E ++F  I   KK G
Sbjct: 500 TSEEE------SQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHG 546



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 117/560 (20%), Positives = 210/560 (37%), Gaps = 52/560 (9%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +    ++V+ LL ++  +N +D   R+ALI AV   E +  ++LL+H  D    D
Sbjct: 177 LHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPD 236

Query: 82  VYGKLAEDYAMSPQKQPAEKAT----SDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVI 137
            YG     YA+  + +   KA     +D +    +  T +  G     V  QKQ   K +
Sbjct: 237 EYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQKQQVVKFL 291

Query: 138 FKKKVSL--------LNIATRIMGGGKSGTVSSQKQPASKTASDKT-DSALNTATEIKDG 188
            KKK +L          +   +  G  S      +Q    ++ D +  +A   A      
Sbjct: 292 IKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHH 351

Query: 189 LQCGTVSSQKQQALKATTDEEGSVS---NIATEIKDGEKSGTVSSQKKPALKATSDEKDS 245
           + C  +S  K++ +   + E  +      + +E +     G+ +SQ +   +     KD 
Sbjct: 352 VICQLLSDYKEKQMLKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELEINKDG 411

Query: 246 FSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLK 305
              +  E K  E S  V   +      T+   D+ L   R      KSRT    Q P  +
Sbjct: 412 DREVEEEMKKHE-SNNVGLLENLTNGVTAGNGDNGLIPQR------KSRTPENQQFPDNE 464

Query: 306 ATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVS 365
           +    +   L     +K   K    +S  +  LK TS+E+   S   +G ++G+  ++  
Sbjct: 465 SEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEE---SQRLKGSENGQPEKR-- 519

Query: 366 SQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKY 425
           SQ+P   K    E ++ + I    K G            G  A + +         G   
Sbjct: 520 SQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDD--------GLIP 571

Query: 426 GEKTKRVSSRKKPSLE----ATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEE 481
             K++   S++ P  E     + ++ D+      E+  G +  ++   +   ++      
Sbjct: 572 PRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMN 631

Query: 482 DSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPA 541
             +    ++ KD     +   E+   L+   D       + R KK  E   +V  +    
Sbjct: 632 SELSLSCKKEKDVLHENSTLREEIAMLRLELDTMKHQSQL-REKKYLEDIESVKKKNDNL 690

Query: 542 LKA------TSDEKDSVLYI 555
           LKA      T D+  +VL I
Sbjct: 691 LKALQLNELTMDDDTAVLVI 710


>gi|113413200 PREDICTED: similar to protein expressed in prostate,
           ovary, testis, and placenta 2 [Homo sapiens]
          Length = 1038

 Score = 93.2 bits (230), Expect = 7e-19
 Identities = 86/293 (29%), Positives = 135/293 (46%), Gaps = 50/293 (17%)

Query: 8   LLGYNVQILNEY--QPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N++   PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 223 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 282

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQ-- 122
           IV LLL+ NIDV S+D+ G+ A +YA+S       +  SD K+  +  I++E    +Q  
Sbjct: 283 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 342

Query: 123 -------------SGTVSPQKQSAQKVIFK---------------KKVSLL-NIATRI-M 152
                        S    P+K S +  I K                 V LL N++  +  
Sbjct: 343 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTA 402

Query: 153 GGGKSGTVSSQKQ--PASKTASDKTDSALNTATEI------KDGLQCGTVSSQKQQALKA 204
           G G  G +  +K   P ++   D      +   E+      K   +  + +S  +Q LK 
Sbjct: 403 GNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKL 462

Query: 205 TTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSD-EKDSFSNITREKKDG 256
           T++EE      +  +K  E        ++P +    D E ++F  I   KK G
Sbjct: 463 TSEEE------SQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHG 509



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 97/408 (23%), Positives = 162/408 (39%), Gaps = 55/408 (13%)

Query: 12  NVQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLL 71
           N Q   +   L LA +     +V+ LL ++  +N +D   R+AL  AV   E +  ++LL
Sbjct: 130 NKQDKQKRTALHLASANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLL 189

Query: 72  QHNIDVFSRDVYGKLAEDYAMSPQKQPAEKAT----SDEKDSVSNIATEIKEGQQSGTVS 127
           +H  D    D YG     YA+  + +   KA     +D +    +  T +  G     V 
Sbjct: 190 EHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VH 244

Query: 128 PQKQSAQKVIFKKKVSLLNI----ATRIMGGGKSGTVS------------SQKQPASKTA 171
            QKQ   K + KKK +L  +     T ++     G+ S            S +  + +TA
Sbjct: 245 EQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTA 304

Query: 172 SDKTDSA-------LNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEK 224
            +   S+       L +  + K  L+  + +S  +Q LK T++EE      +   K  E 
Sbjct: 305 REYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEE------SQRFKGSEN 358

Query: 225 SGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIA 284
           S      ++P +      KD    +  E K  E S  V   +  +   T+   D  L   
Sbjct: 359 SQPEKMSQEPEI-----NKDGDREVEEEMKKHE-SNNVGLLENLSNGVTAGNGDDGLIPQ 412

Query: 285 REKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDE 344
           R      KSRT    Q P  ++    +   L     +K   K    +S  +  LK TS+E
Sbjct: 413 R------KSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEE 466

Query: 345 KDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDG 392
           +   S   +G ++G+  ++  SQ+P   K    E ++ + I    K G
Sbjct: 467 E---SQRLKGSENGQPEKR--SQEPEINKDGDRELENFMAIEEMKKHG 509


>gi|88953571 PREDICTED: similar to protein expressed in prostate,
           ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
          Length = 1075

 Score = 93.2 bits (230), Expect = 7e-19
 Identities = 86/293 (29%), Positives = 135/293 (46%), Gaps = 50/293 (17%)

Query: 8   LLGYNVQILNEY--QPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N++   PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQ-- 122
           IV LLL+ NIDV S+D+ G+ A +YA+S       +  SD K+  +  I++E    +Q  
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 379

Query: 123 -------------SGTVSPQKQSAQKVIFK---------------KKVSLL-NIATRI-M 152
                        S    P+K S +  I K                 V LL N++  +  
Sbjct: 380 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTA 439

Query: 153 GGGKSGTVSSQKQ--PASKTASDKTDSALNTATEI------KDGLQCGTVSSQKQQALKA 204
           G G  G +  +K   P ++   D      +   E+      K   +  + +S  +Q LK 
Sbjct: 440 GNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKL 499

Query: 205 TTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSD-EKDSFSNITREKKDG 256
           T++EE      +  +K  E        ++P +    D E ++F  I   KK G
Sbjct: 500 TSEEE------SQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHG 546



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 112/496 (22%), Positives = 195/496 (39%), Gaps = 67/496 (13%)

Query: 12  NVQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLL 71
           N Q   +   L LA +     +V+ LL ++  +N +D   R+AL  AV   E +  ++LL
Sbjct: 167 NKQDKQKRTALHLASANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLL 226

Query: 72  QHNIDVFSRDVYGKLAEDYAMSPQKQPAEKAT----SDEKDSVSNIATEIKEGQQSGTVS 127
           +H  D    D YG     YA+  + +   KA     +D +    +  T +  G     V 
Sbjct: 227 EHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VH 281

Query: 128 PQKQSAQKVIFKKKVSLLNI----ATRIMGGGKSGTVS------------SQKQPASKTA 171
            QKQ   K + KKK +L  +     T ++     G+ S            S +  + +TA
Sbjct: 282 EQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTA 341

Query: 172 SDKTDSA-------LNTATEIKDGLQCGTVSSQKQQALKATTDEE-----GSVSNIATEI 219
            +   S+       L +  + K  L+  + +S  +Q LK T++EE     GS ++   ++
Sbjct: 342 REYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKM 401

Query: 220 -------KDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEI----SRTVSSQKPP 268
                  KDG++      +K  +      E  S         DG I    SRT  +Q+ P
Sbjct: 402 SQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFP 461

Query: 269 ALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTR 328
             ++        L    ++K   K  + + +    LK T +E+   L   +G +NG+  +
Sbjct: 462 DNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRL---KGSENGQPEK 518

Query: 329 RVSSRKKPALKATSD-EKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAR 387
           R    ++P +    D E ++F  I   KK G  S  V   +  T   T+   D  L   R
Sbjct: 519 R---SQEPEINKDGDRELENFMAIEEMKKHG--STHVGFPENLTNGATAGNGDDGLIPPR 573

Query: 388 ENKDGEKSRTVSSEKPPGLK----ASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEAT 443
                 KSRT  S++ P  +     S ++ D+       +  G     +   ++  +E  
Sbjct: 574 ------KSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVV 627

Query: 444 SDEKDSFSNITREKKD 459
                  S   +++KD
Sbjct: 628 EKMNSELSLSCKKEKD 643


>gi|153791352 prostate, ovary, testis expressed protein on
           chromosome 2 [Homo sapiens]
          Length = 1075

 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 85/291 (29%), Positives = 132/291 (45%), Gaps = 50/291 (17%)

Query: 8   LLGYNVQILNEY--QPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N++   PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQ-- 122
           IV LLL+ NIDV S+D+ G+ A +YA+S       +  SD K+  +  I++E    +Q  
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 379

Query: 123 -------------SGTVSPQKQSAQKVIFK---------------KKVSLLNIATR--IM 152
                        S    P+K S +  I K                 V LL   T     
Sbjct: 380 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVTA 439

Query: 153 GGGKSGTVSSQKQ--PASKTASDKTDSALNTATEI------KDGLQCGTVSSQKQQALKA 204
           G G +G +  +K   P ++   D      +   E+      K   +  + +S  +Q LK 
Sbjct: 440 GNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKL 499

Query: 205 TTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSD-EKDSFSNITREKK 254
           T++EE      +  +K  E        ++P +    D E ++F  I   KK
Sbjct: 500 TSEEE------SQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKK 544



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 130/583 (22%), Positives = 227/583 (38%), Gaps = 78/583 (13%)

Query: 12  NVQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLL 71
           N Q   +   L LA +    ++V+ LL ++  +N +D   R+ALI AV   E +  ++LL
Sbjct: 167 NKQDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLL 226

Query: 72  QHNIDVFSRDVYGKLAEDYAMSPQKQPAEKAT----SDEKDSVSNIATEIKEGQQSGTVS 127
           +H  D    D YG     YA+  + +   KA     +D +    +  T +  G     V 
Sbjct: 227 EHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VH 281

Query: 128 PQKQSAQKVIFKKKVSLLNI----ATRIMGGGKSGTVS------------SQKQPASKTA 171
            QKQ   K + KKK +L  +     T ++     G+ S            S +  + +TA
Sbjct: 282 EQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTA 341

Query: 172 SDKTDSA-------LNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEK 224
            +   S+       L +  + K  L+  + +S  +Q LK T++EE      +   K  E 
Sbjct: 342 REYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEE------SQRFKGSEN 395

Query: 225 SGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIA 284
           S      ++P +      KD    +  E K  E S  V   +      T+   D+ L   
Sbjct: 396 SQPEKMSQEPEI-----NKDGDREVEEEMKKHE-SNNVGLLENLTNGVTAGNGDNGLIPQ 449

Query: 285 REKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDE 344
           R      KSRT    Q P  ++    +   L     +K   K    +S  +  LK TS+E
Sbjct: 450 R------KSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEE 503

Query: 345 KDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 404
           +   S   +G ++G+  ++  SQ+P   K    E ++ + I    ++ +K R+     P 
Sbjct: 504 E---SQRLKGSENGQPEKR--SQEPEINKDGDRELENFMAI----EEMKKHRSTHVGFPE 554

Query: 405 GLK--ASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLE----ATSDEKDSFSNITREKK 458
            L   A++   D  L   R      K++   S++ P  E     + ++ D+      E+ 
Sbjct: 555 NLTNGATAGNGDDGLIPPR------KSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQN 608

Query: 459 DGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSV 518
            G +  ++   +   ++        +    ++ KD     +   E+   L+   D     
Sbjct: 609 TGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQ 668

Query: 519 LNIARGKKDGEKTRTVSSRKKPALKA------TSDEKDSVLYI 555
             + R KK  E   +V  R    LKA      T D+  +VL I
Sbjct: 669 SQL-REKKYLEDIESVKKRNDNLLKALQLNELTMDDDTAVLVI 710


>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
           sapiens]
          Length = 823

 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 84/276 (30%), Positives = 134/276 (48%), Gaps = 35/276 (12%)

Query: 21  PLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSR 80
           PLL A+  +K KMVEFLLKKKA+ +A+D L RSAL+LAV      IV +LL+ NIDVF++
Sbjct: 169 PLLFAIICKKEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQ 228

Query: 81  DVYGKLAEDYAMSP-----------------QKQPAEKATSDEKDSVSNIATEIKEGQQS 123
           D+ G+ AEDYA+S                  +K+ ++  +SDE  S  +I  E++     
Sbjct: 229 DMCGRDAEDYAISHHLTKIQQQILEHKKKILKKEKSDVGSSDE--SAVSIFHELRVDSLP 286

Query: 124 GTVSPQKQSAQKVIFKKKV------SLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 177
            +       A K    +KV      S      RI+ G   G  +  K P+ K +++  D 
Sbjct: 287 ASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPA--KHPSLKPSTEVEDP 344

Query: 178 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 237
           A+  A + K+       + + +QAL   ++EE      + + +   K G  ++ K   ++
Sbjct: 345 AVKGAVQRKN-----VQTLRAEQALPVASEEEQERHERSEKKQPQVKEGN-NTNKSEKIQ 398

Query: 238 ATSDEKDSFSNIT--REKKDGEISRTVSSQKPPALK 271
            + +  DS S+    R  +  +I +T   Q P  LK
Sbjct: 399 LSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLK 434



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 80/389 (20%), Positives = 154/389 (39%), Gaps = 30/389 (7%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +   V++V  L+ +K  ++  D   R+ LI AV   E+   ++LL+H  +   +D
Sbjct: 71  LHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKD 130

Query: 82  VYGKLAEDYAM-SPQKQPAEKATS--------DEKDSVSNIATEIKEGQQSGTVSPQKQS 132
           +YG  A  YA+ S     AEK  S        D+ ++   +   I + ++      +K++
Sbjct: 131 IYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKA 190

Query: 133 AQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPA---SKTASDKTDSAL-NTATEIKDG 188
           +   + + + S L +A      G    +  Q            D  D A+ +  T+I+  
Sbjct: 191 SSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQ 250

Query: 189 LQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSN 248
           +        K++     + +E +VS I  E++      +       A K    EK S   
Sbjct: 251 ILEHKKKILKKEKSDVGSSDESAVS-IFHELRVDSLPASDDKDLNVATKQCVPEKVSEPL 309

Query: 249 ITREKKDGEISRTVSSQ------KPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPP 302
                + G  +R V+ Q      K P+LK ++  ED  +  A ++K+ +  R        
Sbjct: 310 PGSSHEKG--NRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQ----- 362

Query: 303 GLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISR 362
                  E++   +    KK  +     ++ K   ++ + +  DS S+   G+   +  R
Sbjct: 363 -ALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQ--R 419

Query: 363 KVSSQKPPTLKGTSDEEDSVLGIARENKD 391
           K+    P        EE     + +EN++
Sbjct: 420 KIGKTYPQQFPKKLKEEHDRCTLKQENEE 448


>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
           sapiens]
          Length = 823

 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 84/276 (30%), Positives = 134/276 (48%), Gaps = 35/276 (12%)

Query: 21  PLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSR 80
           PLL A+  +K KMVEFLLKKKA+ +A+D L RSAL+LAV      IV +LL+ NIDVF++
Sbjct: 169 PLLFAIICKKEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQ 228

Query: 81  DVYGKLAEDYAMSP-----------------QKQPAEKATSDEKDSVSNIATEIKEGQQS 123
           D+ G+ AEDYA+S                  +K+ ++  +SDE  S  +I  E++     
Sbjct: 229 DMCGRDAEDYAISHHLTKIQQQILEHKKKILKKEKSDVGSSDE--SAVSIFHELRVDSLP 286

Query: 124 GTVSPQKQSAQKVIFKKKV------SLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 177
            +       A K    +KV      S      RI+ G   G  +  K P+ K +++  D 
Sbjct: 287 ASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPA--KHPSLKPSTEVEDP 344

Query: 178 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 237
           A+  A + K+       + + +QAL   ++EE      + + +   K G  ++ K   ++
Sbjct: 345 AVKGAVQRKN-----VQTLRAEQALPVASEEEQQRHERSEKKQPQVKEGN-NTNKSEKIQ 398

Query: 238 ATSDEKDSFSNIT--REKKDGEISRTVSSQKPPALK 271
            + +  DS S+    R  +  +I +T   Q P  LK
Sbjct: 399 LSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLK 434



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 80/389 (20%), Positives = 154/389 (39%), Gaps = 30/389 (7%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +   V++V  L+ +K  ++  D   R+ LI AV   E+   ++LL+H  +   +D
Sbjct: 71  LHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKD 130

Query: 82  VYGKLAEDYAM-SPQKQPAEKATS--------DEKDSVSNIATEIKEGQQSGTVSPQKQS 132
           +YG  A  YA+ S     AEK  S        D+ ++   +   I + ++      +K++
Sbjct: 131 IYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKA 190

Query: 133 AQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPA---SKTASDKTDSAL-NTATEIKDG 188
           +   + + + S L +A      G    +  Q            D  D A+ +  T+I+  
Sbjct: 191 SSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQ 250

Query: 189 LQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSN 248
           +        K++     + +E +VS I  E++      +       A K    EK S   
Sbjct: 251 ILEHKKKILKKEKSDVGSSDESAVS-IFHELRVDSLPASDDKDLNVATKQCVPEKVSEPL 309

Query: 249 ITREKKDGEISRTVSSQ------KPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPP 302
                + G  +R V+ Q      K P+LK ++  ED  +  A ++K+ +  R        
Sbjct: 310 PGSSHEKG--NRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQ----- 362

Query: 303 GLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISR 362
                  E++   +    KK  +     ++ K   ++ + +  DS S+   G+   +  R
Sbjct: 363 -ALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQ--R 419

Query: 363 KVSSQKPPTLKGTSDEEDSVLGIARENKD 391
           K+    P        EE     + +EN++
Sbjct: 420 KIGKTYPQQFPKKLKEEHDRCTLKQENEE 448


>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
           sapiens]
          Length = 823

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 83/276 (30%), Positives = 134/276 (48%), Gaps = 35/276 (12%)

Query: 21  PLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSR 80
           PLL A+  +K KMVEFLLK+KA+ +A+D L RSAL+LAV      IV +LL+ NIDVF++
Sbjct: 169 PLLFAIICKKEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQ 228

Query: 81  DVYGKLAEDYAMSP-----------------QKQPAEKATSDEKDSVSNIATEIKEGQQS 123
           D+ G+ AEDYA+S                  +K+ ++  +SDE  S  +I  E++     
Sbjct: 229 DMCGRDAEDYAISHHLTKIQQQILEHKKKILKKEKSDVGSSDE--SAVSIFHELRVDSLP 286

Query: 124 GTVSPQKQSAQKVIFKKKV------SLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 177
            +       A K    +KV      S      RI+ G   G  +  K P+ K +++  D 
Sbjct: 287 ASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPA--KHPSLKPSTEVEDP 344

Query: 178 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 237
           A+  A + K+       + + +QAL   ++EE      + + +   K G  ++ K   ++
Sbjct: 345 AVKGAVQRKN-----VQTLRAEQALPVASEEEQERHERSEKKQPQVKEGN-NTNKSEKIQ 398

Query: 238 ATSDEKDSFSNIT--REKKDGEISRTVSSQKPPALK 271
            + +  DS S+    R  +  +I +T   Q P  LK
Sbjct: 399 LSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLK 434



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +   V++V  L+ +K  ++  D   R+ LI AV   E+   ++LL+H  +   +D
Sbjct: 71  LHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKD 130

Query: 82  VYGKLAEDYAM-SPQKQPAEKATS 104
           +YG  A  YA+ S     AEK  S
Sbjct: 131 IYGNTALHYAVYSESTSLAEKLLS 154


>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
           sapiens]
          Length = 823

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 83/276 (30%), Positives = 134/276 (48%), Gaps = 35/276 (12%)

Query: 21  PLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSR 80
           PLL A+  +K KMVEFLLK+KA+ +A+D L RSAL+LAV      IV +LL+ NIDVF++
Sbjct: 169 PLLFAIICKKEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQ 228

Query: 81  DVYGKLAEDYAMSP-----------------QKQPAEKATSDEKDSVSNIATEIKEGQQS 123
           D+ G+ AEDYA+S                  +K+ ++  +SDE  S  +I  E++     
Sbjct: 229 DMCGRDAEDYAISHHLTKIQQQILEHKKKILKKEKSDVGSSDE--SAVSIFHELRVDSLP 286

Query: 124 GTVSPQKQSAQKVIFKKKV------SLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 177
            +       A K    +KV      S      RI+ G   G  +  K P+ K +++  D 
Sbjct: 287 ASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPA--KHPSLKPSTEVEDP 344

Query: 178 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 237
           A+  A + K+       + + +QAL   ++EE      + + +   K G  ++ K   ++
Sbjct: 345 AVKGAVQRKN-----VQTLRAEQALPVASEEEQERHERSEKKQPQVKEGN-NTNKSEKIQ 398

Query: 238 ATSDEKDSFSNIT--REKKDGEISRTVSSQKPPALK 271
            + +  DS S+    R  +  +I +T   Q P  LK
Sbjct: 399 LSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLK 434



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +   V++V  L+ +K  ++  D   R+ LI AV   E+   ++LL+H  +   +D
Sbjct: 71  LHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKD 130

Query: 82  VYGKLAEDYAM-SPQKQPAEKATS 104
           +YG  A  YA+ S     AEK  S
Sbjct: 131 IYGNTALHYAVYSESTSLAEKLLS 154


>gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]
          Length = 545

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 51/128 (39%), Positives = 83/128 (64%), Gaps = 3/128 (2%)

Query: 8   LLGYNVQILNEY--QPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N++   PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 297 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 356

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQSG 124
           IV LLL+ NIDV S+D+ G+ A +YA+S +     +  SD K+  +  +++E    +Q  
Sbjct: 357 IVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQILKVSSENSNPEQDL 416

Query: 125 TVSPQKQS 132
            ++ +++S
Sbjct: 417 KLTSEEES 424



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 61/249 (24%), Positives = 98/249 (39%), Gaps = 38/249 (15%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +    ++V+ LL ++  +N +D   R+AL  AV   E +  ++LL+H  D    D
Sbjct: 214 LHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPD 273

Query: 82  VYGKLAEDYAMSPQKQPAEKAT----SDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVI 137
            YG  A  YA+  + +   KA     +D +    +  T +  G     V  QKQ   K +
Sbjct: 274 EYGNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQKQQVVKFL 328

Query: 138 FKKKVSL--------LNIATRIMGGGKSGT---------VSSQKQPASKTASDKTDSALN 180
            KKK +L          +   +  G  S           VSSQ             S  N
Sbjct: 329 IKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHN 388

Query: 181 TATEI------KDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKP 234
              ++      K  L+  + +S  +Q LK T++EE      +  +K  E S      ++P
Sbjct: 389 VICQLLSDYKEKQILKVSSENSNPEQDLKLTSEEE------SQRLKGSENSQPEEMSQEP 442

Query: 235 ALKATSDEK 243
            +    D K
Sbjct: 443 EINKGGDRK 451


>gi|239741769 PREDICTED: similar to protein expressed in prostate,
           ovary, testis, and placenta 2 [Homo sapiens]
          Length = 952

 Score = 87.4 bits (215), Expect = 4e-17
 Identities = 52/128 (40%), Positives = 82/128 (64%), Gaps = 3/128 (2%)

Query: 8   LLGYNVQILNEY--QPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N++   PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQSG 124
           IV LLL+ NIDV S+D+ G+ A +YA+S       +  SD K+  +  I++E    +Q  
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 379

Query: 125 TVSPQKQS 132
            ++ +++S
Sbjct: 380 KLTSEEES 387



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 61/259 (23%), Positives = 105/259 (40%), Gaps = 38/259 (14%)

Query: 12  NVQILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLL 71
           N Q   +   L LA +     +V+ LL ++  +N +D   R+AL  AV   E +  ++LL
Sbjct: 167 NKQDKQKRTALHLASANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLL 226

Query: 72  QHNIDVFSRDVYGKLAEDYAMSPQKQPAEKAT----SDEKDSVSNIATEIKEGQQSGTVS 127
           +H  D    D YG     YA+  + +   KA     +D +    +  T +  G     V 
Sbjct: 227 EHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VH 281

Query: 128 PQKQSAQKVIFKKKVSLLNI----ATRIMGGGKSGTVS------------SQKQPASKTA 171
            QKQ   K + KKK +L  +     T ++     G+ S            S +  + +TA
Sbjct: 282 EQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTA 341

Query: 172 SDKTDSA-------LNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEK 224
            +   S+       L +  + K  L+  + +S  +Q LK T++EE      +   K  E 
Sbjct: 342 REYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEE------SQRFKGSEN 395

Query: 225 SGTVSSQKKPALKATSDEK 243
           S      ++P +    D +
Sbjct: 396 SQPEKMSQEPEINKDGDRE 414


>gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]
          Length = 508

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 51/128 (39%), Positives = 82/128 (64%), Gaps = 3/128 (2%)

Query: 8   LLGYNVQILNEY--QPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N++   PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQSG 124
           IV LLL+ NIDV S+D+ G+ A +YA+S       +  SD K+  +  +++E    +Q  
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLSDYKEKQMLKVSSENSNPEQDL 379

Query: 125 TVSPQKQS 132
            ++ +++S
Sbjct: 380 KLTSEEES 387



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 61/249 (24%), Positives = 98/249 (39%), Gaps = 38/249 (15%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +    ++V+ LL ++  +N +D   R+AL  AV   E +  ++LL+H  D    D
Sbjct: 177 LHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCREDECALMLLEHGTDPNIPD 236

Query: 82  VYGKLAEDYAMSPQKQPAEKAT----SDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVI 137
            YG  A  YA+  + +   KA     +D +    +  T +  G     V  QKQ   K +
Sbjct: 237 EYGNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQKQQVVKFL 291

Query: 138 FKKKVSL--------LNIATRIMGGGKSGT---------VSSQKQPASKTASDKTDSALN 180
            KKK +L          +   +  G  S           VSSQ             S  N
Sbjct: 292 IKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHN 351

Query: 181 TATEI------KDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKP 234
              ++      K  L+  + +S  +Q LK T++EE      +  +K  E S      ++P
Sbjct: 352 VICQLLSDYKEKQMLKVSSENSNPEQDLKLTSEEE------SQRLKGSENSQPEEMSQEP 405

Query: 235 ALKATSDEK 243
            +    D K
Sbjct: 406 EINKGGDRK 414


>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
          Length = 917

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 61/146 (41%), Positives = 81/146 (55%), Gaps = 17/146 (11%)

Query: 8   LLGYNVQILNEYQP----LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGE 63
           LL Y   I    Q     LLLAV+R+K +MV FLLKKK ++ AID  GR+ALILA   G 
Sbjct: 157 LLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGS 216

Query: 64  KDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQP-----AEKATSDEKDSVSNIATE-- 116
             +V  LLQHNIDVF +D+ G  AEDYA++ + Q      +E   +  + S+ N  +E  
Sbjct: 217 TSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQD 276

Query: 117 ---IKEGQQ---SGTVSPQKQSAQKV 136
                EG+Q    G  S Q Q  +K+
Sbjct: 277 LEMTSEGEQERLEGCESSQPQVEEKM 302



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 101/458 (22%), Positives = 177/458 (38%), Gaps = 74/458 (16%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           LLLA +  +  +V  L+ +K  +N  D   R+ALI AV   E+    +LL+H  +   RD
Sbjct: 76  LLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRD 135

Query: 82  VYGKLAEDYAMSPQK-QPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIF-- 138
           +YG  A  YA+  +    A K  +   D    I    ++G  S  ++  ++  Q V F  
Sbjct: 136 MYGNTALHYAIDNENISMARKLLAYGAD----IEARSQDGHTSLLLAVNRKKEQMVSFLL 191

Query: 139 KKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQK 198
           KKK  L    T I   G++  + + +  ++          ++                  
Sbjct: 192 KKKPDL----TAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFC--------------- 232

Query: 199 QQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEI 258
            Q +   T E+ +V++    I+ G  S   +++++ +L+ ++ E+D    +T E +   +
Sbjct: 233 -QDISGWTAEDYAVASKFQAIR-GMISEYKANKRRKSLQNSNSEQD--LEMTSEGEQERL 288

Query: 259 SRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIA 318
               SSQ          + +  +   R KK  E SR V  D         D+ D L++  
Sbjct: 289 EGCESSQP---------QVEEKMKKCRNKK-MEVSRNVHADDSDNY---NDDVDELIHKI 335

Query: 319 R----------GKKNGE------KTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISR 362
           +          GK+NGE      KT    S+ K  +  T D  D   +  +  +D E+  
Sbjct: 336 KNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELP- 394

Query: 363 KVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARG 422
                        SD+E+ +L I +   + +   ++S  K          +D      R 
Sbjct: 395 ------------YSDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERL 442

Query: 423 KKYGEKTKRVSSRKKPSLEATSDEK--DSFSNITREKK 458
           K   +K K   S  +  L  T   K      N+  +KK
Sbjct: 443 KVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480


>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
           sapiens]
          Length = 917

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 61/146 (41%), Positives = 81/146 (55%), Gaps = 17/146 (11%)

Query: 8   LLGYNVQILNEYQP----LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGE 63
           LL Y   I    Q     LLLAV+R+K +MV FLLKKK ++ AID  GR+ALILA   G 
Sbjct: 157 LLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGS 216

Query: 64  KDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQP-----AEKATSDEKDSVSNIATE-- 116
             +V  LLQHNIDVF +D+ G  AEDYA++ + Q      +E   +  + S+ N  +E  
Sbjct: 217 TSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQD 276

Query: 117 ---IKEGQQ---SGTVSPQKQSAQKV 136
                EG+Q    G  S Q Q  +K+
Sbjct: 277 LEMTSEGEQERLEGCESSQPQVEEKM 302



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 101/458 (22%), Positives = 177/458 (38%), Gaps = 74/458 (16%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           LLLA +  +  +V  L+ +K  +N  D   R+ALI AV   E+    +LL+H  +   RD
Sbjct: 76  LLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRD 135

Query: 82  VYGKLAEDYAMSPQK-QPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIF-- 138
           +YG  A  YA+  +    A K  +   D    I    ++G  S  ++  ++  Q V F  
Sbjct: 136 MYGNTALHYAIDNENISMARKLLAYGAD----IEARSQDGHTSLLLAVNRKKEQMVSFLL 191

Query: 139 KKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQK 198
           KKK  L    T I   G++  + + +  ++          ++                  
Sbjct: 192 KKKPDL----TAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFC--------------- 232

Query: 199 QQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEI 258
            Q +   T E+ +V++    I+ G  S   +++++ +L+ ++ E+D    +T E +   +
Sbjct: 233 -QDISGWTAEDYAVASKFQAIR-GMISEYKANKRRKSLQNSNSEQD--LEMTSEGEQERL 288

Query: 259 SRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIA 318
               SSQ          + +  +   R KK  E SR V  D         D+ D L++  
Sbjct: 289 EGCESSQP---------QVEEKMKKCRNKK-MEVSRNVHADDSDNY---NDDVDELIHKI 335

Query: 319 R----------GKKNGE------KTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISR 362
           +          GK+NGE      KT    S+ K  +  T D  D   +  +  +D E+  
Sbjct: 336 KNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELP- 394

Query: 363 KVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARG 422
                        SD+E+ +L I +   + +   ++S  K          +D      R 
Sbjct: 395 ------------YSDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERL 442

Query: 423 KKYGEKTKRVSSRKKPSLEATSDEK--DSFSNITREKK 458
           K   +K K   S  +  L  T   K      N+  +KK
Sbjct: 443 KVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480


>gi|224282147 prostate-specific P704P [Homo sapiens]
          Length = 508

 Score = 86.7 bits (213), Expect = 7e-17
 Identities = 50/128 (39%), Positives = 82/128 (64%), Gaps = 3/128 (2%)

Query: 8   LLGYNVQILNEY--QPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N++   PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ LILAV  G   
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTVLILAVCCGSAS 319

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQSG 124
           IV LLL+ NIDV S+D+ G+ A +YA+S +     +  SD K+  +  +++E    +Q  
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQILKVSSENSNPEQDL 379

Query: 125 TVSPQKQS 132
            ++ +++S
Sbjct: 380 KLTSEEES 387



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 61/249 (24%), Positives = 104/249 (41%), Gaps = 38/249 (15%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +    ++V+ LL ++  +N +D   R+AL  AV   E +  ++LL+H  D    D
Sbjct: 177 LHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPD 236

Query: 82  VYGKLAEDYAMSPQKQPAEKAT----SDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVI 137
            YG  A  YA+  + +   KA     +D +    +  T +  G     V  QKQ   K +
Sbjct: 237 EYGNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQKQQVVKFL 291

Query: 138 FKKKVSL-------LNIATRIMGGGKSGTVS---------SQKQPASKTASDKTDSA--- 178
            KKK +L         +    +  G +  VS         S +  + +TA +   S+   
Sbjct: 292 IKKKANLNALDRYGRTVLILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHN 351

Query: 179 ----LNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKP 234
               L +  + K  L+  + +S  +Q LK T++EE      +  +K  E S      ++P
Sbjct: 352 VICQLLSDYKEKQILKVSSENSNPEQDLKLTSEEE------SQRLKGSENSQPEEMSQEP 405

Query: 235 ALKATSDEK 243
            +    D K
Sbjct: 406 EINKGGDRK 414


>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
           sapiens]
          Length = 917

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 62/146 (42%), Positives = 80/146 (54%), Gaps = 17/146 (11%)

Query: 8   LLGYNVQILNEYQP----LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGE 63
           LL Y   I    Q     LLLAV+R+K +MV FLLKKK ++ AID  GR+ALILA   G 
Sbjct: 157 LLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRTALILAARNGS 216

Query: 64  KDIVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEK-----DSVSNIATE-- 116
             +V  LLQHNIDVF +D+ G  AEDYA++ + Q      S+ K      S+ N  +E  
Sbjct: 217 TSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRCKSLQNSNSEQD 276

Query: 117 ---IKEGQQ---SGTVSPQKQSAQKV 136
                EG+Q    G  S Q Q  +K+
Sbjct: 277 LEMTSEGEQERLEGCESSQPQVEEKM 302



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 101/458 (22%), Positives = 176/458 (38%), Gaps = 74/458 (16%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           LLLA +  +  +V  L+ +K  +N  D   R+ALI AV   E+    +LL+H  +   RD
Sbjct: 76  LLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRD 135

Query: 82  VYGKLAEDYAMSPQK-QPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIF-- 138
           +YG  A  YA+  +    A K  +   D    I    ++G  S  ++  ++  Q V F  
Sbjct: 136 MYGNTALHYAIDNENISMARKLLAYGAD----IEARSQDGHTSLLLAVNRKKEQMVAFLL 191

Query: 139 KKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQK 198
           KKK  L    T I   G++  + + +  ++          ++                  
Sbjct: 192 KKKPDL----TAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFC--------------- 232

Query: 199 QQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEI 258
            Q +   T E+ +V++    I+ G  S   ++++  +L+ ++ E+D    +T E +   +
Sbjct: 233 -QDISGWTAEDYAVASKFQAIR-GMISEYKANKRCKSLQNSNSEQD--LEMTSEGEQERL 288

Query: 259 SRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIA 318
               SSQ          + +  +   R KK  E SR V  D         D+ D L++  
Sbjct: 289 EGCESSQP---------QVEEKMKKCRNKK-MEVSRNVHADDSDNY---NDDVDELIHKI 335

Query: 319 R----------GKKNGE------KTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISR 362
           +          GK+NGE      KT    S+ K  +  T D  D   +  +  +D E+  
Sbjct: 336 KNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELP- 394

Query: 363 KVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARG 422
                        SD+E+ +L I +   + +   ++S  K          +D      R 
Sbjct: 395 ------------YSDDENFMLLIEQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERL 442

Query: 423 KKYGEKTKRVSSRKKPSLEATSDEK--DSFSNITREKK 458
           K   +K K   S  +  L  T   K      N+  +KK
Sbjct: 443 KVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480


>gi|52856430 protein expressed in prostate, ovary, testis, and
           placenta 15 [Homo sapiens]
          Length = 581

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 84/322 (26%), Positives = 144/322 (44%), Gaps = 54/322 (16%)

Query: 8   LLGYNVQILNE--YQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N+    PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 260 LYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQ-- 122
           IV LLL+ N+DV S+D+ G+ A +YA+S       +  SD K+  +  I++E    +Q  
Sbjct: 320 IVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDL 379

Query: 123 -------------SGTVSPQKQSAQKVIFK----------KK---------VSLLNIATR 150
                        S    P+K S +  I K          KK          +L N A+ 
Sbjct: 380 KLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGAS- 438

Query: 151 IMGGGKSGTVSSQKQPASKT------------ASDKTDSALNTATEIKDGLQCGTVSSQK 198
             G G  G +  +K    +             + ++ D+    + E   G+    + + K
Sbjct: 439 -AGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNK 497

Query: 199 QQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEI 258
           Q+ ++    E  S  +++ + ++         +++ A+     ++    N  RE K   I
Sbjct: 498 QKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENK---I 554

Query: 259 SRTVSSQKPPALKATSVKEDSV 280
              + S K   LKA  + E+++
Sbjct: 555 LEEIESVKEKLLKAIQLNEEAL 576



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 89/411 (21%), Positives = 166/411 (40%), Gaps = 54/411 (13%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +    ++V+ LL ++  +N +D   R+ALI AV   E + V++LL+H  D   +D
Sbjct: 177 LHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQD 236

Query: 82  VYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGT------VSPQKQSAQK 135
            YG  A  YA+  + +   KA       +     +I+   + G       V  QKQ   K
Sbjct: 237 EYGNTALHYAIYNEDKLMAKA-------LLLYGADIESKNKCGLTPLLLGVHEQKQQVVK 289

Query: 136 VIFKKKVSLLNI----ATRIMGGGKSGTVS------------SQKQPASKTASDKTDSA- 178
            + KKK +L  +     T ++     G+ S            S +  + +TA +   S+ 
Sbjct: 290 FLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSH 349

Query: 179 ------LNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQK 232
                 L +  + K  L+  + +S  +Q LK T++EE      +  +K  E S      +
Sbjct: 350 HHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEE------SQRLKVSENSQPEKMSQ 403

Query: 233 KPALKATSDEKDSFSNITRE-KKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGE 291
           +P +      KD    +  E KK G  S  V   +     A++   D  L   R+ +  E
Sbjct: 404 EPEI-----NKDCDREVEEEIKKHG--SNPVGLPENLTNGASAGNGDDGLIPQRKSRKPE 456

Query: 292 KSRTVSFDQPPGLKATRDEK-DSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSN 350
             +   F      +   DE+ D+   ++  +  G     + + K+  ++    E +S  +
Sbjct: 457 NQQ---FPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSKLS 513

Query: 351 ITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSE 401
           ++  K++  +      ++   +     +E       RENK  E+  +V  +
Sbjct: 514 LSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENKILEEIESVKEK 564


>gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens]
          Length = 542

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 51/128 (39%), Positives = 81/128 (63%), Gaps = 3/128 (2%)

Query: 8   LLGYNVQILNE--YQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N+    PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 260 LYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQSG 124
           IV LLL+ N+DV S+D+ G+ A +YA+S       +  SD K+  +  I++E    +Q  
Sbjct: 320 IVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDL 379

Query: 125 TVSPQKQS 132
            ++ +++S
Sbjct: 380 KLTSEEES 387



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 60/251 (23%), Positives = 105/251 (41%), Gaps = 42/251 (16%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +    ++V+ LL ++  +N +D   R+ALI AV   E + V++LL+H  D    D
Sbjct: 177 LHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADQNIPD 236

Query: 82  VYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGT------VSPQKQSAQK 135
            YG     YA+  + +   KA       +     +I+   + G       V  QKQ   K
Sbjct: 237 EYGNTTLHYAVHNEDKLMAKA-------LLLYGADIESKNKCGLTPLLLGVHEQKQQVVK 289

Query: 136 VIFKKKVSLLNI----ATRIMGGGKSGTVS------------SQKQPASKTASDKTDSA- 178
            + KKK +L  +     T ++     G+ S            S +  + +TA +   S+ 
Sbjct: 290 FLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSH 349

Query: 179 ------LNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQK 232
                 L +  + K  L+  + +S  +Q LK T++EE      +  +K  E S      +
Sbjct: 350 HHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEE------SQRLKVSENSQPEKMSQ 403

Query: 233 KPALKATSDEK 243
           +P +    D +
Sbjct: 404 EPEINKDCDRE 414


>gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
           sapiens]
          Length = 544

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 51/128 (39%), Positives = 81/128 (63%), Gaps = 3/128 (2%)

Query: 8   LLGYNVQILNE--YQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKD 65
           L G +++  N+    PLLL V  +K ++V+FL+KKKAN+NA+D  GR+ALILAV  G   
Sbjct: 223 LYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 282

Query: 66  IVILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKD-SVSNIATEIKEGQQSG 124
           IV LLL+ N+DV S+D+ G+ A +YA+S       +  SD K+  +  I++E    +Q  
Sbjct: 283 IVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDL 342

Query: 125 TVSPQKQS 132
            ++ +++S
Sbjct: 343 KLTSEEES 350



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 93/412 (22%), Positives = 170/412 (41%), Gaps = 56/412 (13%)

Query: 22  LLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRD 81
           L LA +    ++V+ LL ++  +N +D   R+ALI AV   E + V++LL+H  D   +D
Sbjct: 140 LHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQD 199

Query: 82  VYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGT------VSPQKQSAQK 135
            YG  A  YA+  + +   KA       +     +I+   + G       V  QKQ   K
Sbjct: 200 EYGNTALHYAIYNEDKLMAKA-------LLLYGADIESKNKCGLTPLLLGVHEQKQEVVK 252

Query: 136 VIFKKKVSLLNI----ATRIMGGGKSGTVS------------SQKQPASKTASDKTDSA- 178
            + KKK +L  +     T ++     G+ S            S +  + +TA +   S+ 
Sbjct: 253 FLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSH 312

Query: 179 ------LNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQK 232
                 L +  + K  L+  + +S  +Q LK T++EE      +  +K  E S      +
Sbjct: 313 HHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEE------SQRLKVSENSQPEKMSQ 366

Query: 233 KPALKATSDEKDSFSNITRE-KKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGE 291
           +P +      KD    +  E KK G  S  V   +     A++   D  L   R+ +  E
Sbjct: 367 EPEI-----NKDCDREVEEEIKKHG--SNPVGLPENLTNGASAGNGDDGLIPQRKSRKPE 419

Query: 292 KSRTVSFDQPPGLKATRDEK-DSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSN 350
             +   F      +   DE+ D+   ++  +  G     + + K+  ++    E +S  +
Sbjct: 420 NQQ---FPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELS 476

Query: 351 ITRGKKDGEISRKVSSQKPPTLKGTSD-EEDSVLGIARENKDGEKSRTVSSE 401
           ++  KK+ ++ R+ S  +    K   + +E       RENK  E+  +V  +
Sbjct: 477 LSH-KKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKEK 527


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.121    0.312 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,327,815
Number of Sequences: 37866
Number of extensions: 1135726
Number of successful extensions: 6138
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 247
Number of HSP's successfully gapped in prelim test: 487
Number of HSP's that attempted gapping in prelim test: 3654
Number of HSP's gapped (non-prelim): 2069
length of query: 710
length of database: 18,247,518
effective HSP length: 109
effective length of query: 601
effective length of database: 14,120,124
effective search space: 8486194524
effective search space used: 8486194524
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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