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Search of human proteins with 239753231
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
(948 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 1819 0.0
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 1459 0.0
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 1253 0.0
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 885 0.0
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 610 e-174
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 605 e-173
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 267 4e-71
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 235 1e-61
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 87 7e-17
gi|104526627 triadin [Homo sapiens] 78 3e-14
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 76 1e-13
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 76 2e-13
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 75 3e-13
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 75 3e-13
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 74 8e-13
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 68 5e-11
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 68 5e-11
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 68 5e-11
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 68 5e-11
gi|125656165 THO complex 2 [Homo sapiens] 67 8e-11
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 65 3e-10
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 65 3e-10
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 65 4e-10
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 65 4e-10
gi|217330641 IWS1 homolog [Homo sapiens] 64 5e-10
gi|59814411 hypothetical protein LOC253725 [Homo sapiens] 64 5e-10
gi|4557509 cylicin 2 [Homo sapiens] 64 7e-10
gi|54124343 hypothetical protein LOC387680 [Homo sapiens] 64 9e-10
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 63 1e-09
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 63 1e-09
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 1819 bits (4711), Expect = 0.0
Identities = 948/948 (100%), Positives = 948/948 (100%)
Query: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ
Sbjct: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
Query: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY
Sbjct: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
Query: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV
Sbjct: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL
Sbjct: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS
Sbjct: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
Query: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGG 360
QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGG
Sbjct: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGG 360
Query: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN
Sbjct: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
Query: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
DEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQK
Sbjct: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
Query: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEK 600
PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEK
Sbjct: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEK 600
Query: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA
Sbjct: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
Query: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDE 720
RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDE
Sbjct: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDE 720
Query: 721 EDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKP 780
EDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKP
Sbjct: 721 EDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKP 780
Query: 781 ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISG 840
ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISG
Sbjct: 781 ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISG 840
Query: 841 TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIATR 900
TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIATR
Sbjct: 841 TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIATR 900
Query: 901 ITGGWKSGTVIRQAIEHDECLCYTGIKPSDVLYESHAVAVSTSFYTYF 948
ITGGWKSGTVIRQAIEHDECLCYTGIKPSDVLYESHAVAVSTSFYTYF
Sbjct: 901 ITGGWKSGTVIRQAIEHDECLCYTGIKPSDVLYESHAVAVSTSFYTYF 948
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 1459 bits (3778), Expect = 0.0
Identities = 788/899 (87%), Positives = 809/899 (89%), Gaps = 26/899 (2%)
Query: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ
Sbjct: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
Query: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY
Sbjct: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
Query: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV
Sbjct: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL
Sbjct: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS
Sbjct: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
Query: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGG 360
QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSA KVIFKKKVSLLNIATRIMGG
Sbjct: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGG 360
Query: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN
Sbjct: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
Query: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
DEEGSVLSIARENKDGEKSRTVSSRKKPA KATSDEKDSFSNITRGKKDGEISRKVSSQK
Sbjct: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
Query: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEK 600
PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASS EKDSVLNIARGKK GEK
Sbjct: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEK 600
Query: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA
Sbjct: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
Query: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDE 720
RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSS K P LKA D+
Sbjct: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDK 720
Query: 721 EDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKP 780
EDSV ++A E KD + S TVS +K LKATS +KDSV NI K G+++ VSS+K+P
Sbjct: 721 EDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQP 780
Query: 781 ALKATSDEKDSVLYIAREKKDGE--------------------------KSRTVSSQKQP 814
A KATS +KDSV IA E KDG+ KS VS QKQ
Sbjct: 781 AWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQS 840
Query: 815 ALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQS 873
A K I K+ S+ N+AT SGT + P LKAT + K+SV N T++KD Q S
Sbjct: 841 AQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 899
Score = 329 bits (843), Expect = 9e-90
Identities = 256/669 (38%), Positives = 340/669 (50%), Gaps = 44/669 (6%)
Query: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
VSSQKQPA K TSD+ DSVSN ATEIK Q+SGTV P + + ++ T
Sbjct: 298 VSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI 357
Query: 80 EFSLESEIISKLYIPKRKIISPR--SIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALE 137
+S +S P K S + S ++ +++ + +C + + QP K E
Sbjct: 358 MGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGL-QCGTVSSQ-KQPALKATTDEE 415
Query: 138 SE--NISEPYFTNRR--TISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQK 193
NI+ + T+S Q L A + + E ++ +K G
Sbjct: 416 DSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSG--------- 466
Query: 194 ANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAM 253
VS ++PP T T + + + D S SS + P T E D S
Sbjct: 467 -TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITR 525
Query: 254 RRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEK 313
+KD KVSSQK P K TSD++DSV IA E K+G S TVSS+K P KA+S EK
Sbjct: 526 GKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEK 585
Query: 314 DSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPA 373
DSV NIA K G+++ VS +K+ + + +K S NI G S VSSQK PA
Sbjct: 586 DSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPA 645
Query: 374 SKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGT 433
K TSD+ DS L IA E KDG + TVSS+K P LKAT+DE+DSV NIA KDGEK+ T
Sbjct: 646 LKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRT 705
Query: 434 VSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIAREN 493
VSS KQPALKA D++DSV N+ATE KD + SGTVS QK PAL ATSD++ SV +I E
Sbjct: 706 VSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEI 765
Query: 494 KDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI--------------------- 532
KDG++S TVSS+K+PA KATS +KDS SNI KDG+I
Sbjct: 766 KDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKF 825
Query: 533 -----SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDS 587
S VS QK K ++ S+L IA G KS T E P LKA+ + K+S
Sbjct: 826 TSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNS 885
Query: 588 VLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALK 647
VLN A K + + + + E + + N + K+ SR + +
Sbjct: 886 VLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQ 945
Query: 648 GTSDEEDSV 656
S++ DS+
Sbjct: 946 TVSEDGDSL 954
Score = 59.7 bits (143), Expect = 1e-08
Identities = 37/88 (42%), Positives = 50/88 (56%)
Query: 805 SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP 864
S VSSQKQPALK DK+DSV N ATE KDEQ SGTV + L + + D+V+
Sbjct: 17 SLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPV 76
Query: 865 TEIKDGQQSGTVSPQKQSAQKVIFKKKV 892
TE + +S +S +K+I + +
Sbjct: 77 TENEFSLESEIISKLYIPKRKIISPRSI 104
Score = 58.9 bits (141), Expect = 2e-08
Identities = 32/43 (74%), Positives = 33/43 (76%)
Query: 836 EQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSP 878
E S VSSQKQPALK TSDK DSVSN TEIKD Q+SGTV P
Sbjct: 14 ETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLP 56
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 1253 bits (3242), Expect = 0.0
Identities = 684/872 (78%), Positives = 735/872 (84%), Gaps = 17/872 (1%)
Query: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
MVQILKNAASVFSETTSLEVSSQKQPALKDTSDK+DSVSNTATEIKDEQKSGTVLPAVEQ
Sbjct: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQ 60
Query: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
CLNRSLYRPDAVAQPVTE+EF+LESEIISKLYIPKRKIISPRSI+DVLPPVEEAVDRCLY
Sbjct: 61 CLNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLY 120
Query: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
LLDRFAQ VTKDKFALESENISEPYFTNRRTISQQSAE LDAACGIDKTENG +FEDQNV
Sbjct: 121 LLDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNV 180
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
DKEGKALPATGQKANVSPEQPPLFTHTVKD DHISTRFLG MDSLTSSEESSERPPLSTL
Sbjct: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTL 240
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS
Sbjct: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
Query: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGG 360
QKQPAEKATSDEKDSVSNIATEIK+GQQSGTVSPQKQSA KVIFKKKVSLLNIATRI GG
Sbjct: 301 QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGG 360
Query: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
GKSGTVSSQKQP SKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN
Sbjct: 361 GKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
IATEIKDGEKSGTVSSQKQPALKATTDE+DSV NIATEIKDGEKS TVSSQK PAL AT+
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATT 480
Query: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
DEE SV IA E KDGEKS TVSSRKKPA KATSDEKDSFSNITR KKDGEISR VSSQK
Sbjct: 481 DEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 540
Query: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEK 600
PP LK TSDEEDSVL IARE KDGEKSRTVSSE+PPGLKA+ DEKDS+LNIARGKKYGEK
Sbjct: 541 PPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEK 600
Query: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
T+RVSS K+P+L+ATSD+++S N+ E KD +IS VSSQK PALK TSD++DSV I
Sbjct: 601 TRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIP 660
Query: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDE 720
E KDG++S TVSS+K KATS +KDSV NIA KDG+ TVSSQ+ P LKAT DE
Sbjct: 661 TEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDE 720
Query: 721 EDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKP 780
+DSV +IARE KDGEKS TVS +K S K +K S+LNIA G K+ P
Sbjct: 721 KDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLP 780
Query: 781 ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISG 840
LKAT + K+SVL A + KD + S + MA+E + +++
Sbjct: 781 TLKATIENKNSVLNTATKMKDVQTSTPAEQDLE---------------MASEGEQKRLEE 825
Query: 841 TVSSQKQ--PALKATSDKKDSVSNIPTEIKDG 870
++Q Q + + D D + + T +DG
Sbjct: 826 YENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 857
Score = 616 bits (1589), Expect = e-176
Identities = 402/784 (51%), Positives = 466/784 (59%), Gaps = 115/784 (14%)
Query: 263 KVSSQKQPAEKATSDDKDSVSNIAT----EIKEGPISGTVS-----SQKQP---AEKATS 310
+VSSQKQPA K TSD DSVSN AT E K G + V S +P A+ T
Sbjct: 19 EVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 78
Query: 311 DE-----------------------------------------KDSVSNIATEIKKGQQS 329
DE D + T+ K +S
Sbjct: 79 DEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYLLDRFAQAVTKDKFALES 138
Query: 330 GTVSPQKQSARKVIFKKKVSLLNIATRI---------------------MGGGKSGTVSS 368
+S + R+ I ++ L+ A I G+ VS
Sbjct: 139 ENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSP 198
Query: 369 QKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDG 428
++ P T +D D L SS++ P T E D S A KD
Sbjct: 199 EQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDS 258
Query: 429 EKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLS 488
G VSSQKQPA KAT+D+KDSVSNIATEIK+G SGTVSSQK PA ATSDE+ SV +
Sbjct: 259 PPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 318
Query: 489 IARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTS 548
IA E K+G++S TVS +K+ A K +K S NI G S VSSQK P K TS
Sbjct: 319 IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATS 378
Query: 549 DEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRK 608
D+ DS L IA E KDG + TVSS+K P LKA++DE+DSV NIA K GEK+ VSS+K
Sbjct: 379 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 438
Query: 609 KPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEK 668
+P+L+AT+DE+DS NI E KDGE S VSSQK PALK T+DEEDSV IA E KDGEK
Sbjct: 439 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 498
Query: 669 SRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIA 728
S TVSS K P LKATSDEKDS NI R KKDGE +RTVSSQKPP LKATSDEEDSVLSIA
Sbjct: 499 SGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIA 558
Query: 729 RENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDE 788
RE KDGEKSRTVSSE+P GLKAT EKDS+LNIARGKKYGEKT+RVSS K+PALKATSD+
Sbjct: 559 REEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDK 618
Query: 789 KDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNM------------------- 829
++SV +A E KD + S TVSSQKQPALKA DK+DSV N+
Sbjct: 619 ENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQL 678
Query: 830 ---------------ATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSG 874
ATE KD QI GTVSSQ+QPALKAT D+KDSVSNI EIKDG++SG
Sbjct: 679 AWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSG 738
Query: 875 TVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGT-------VIRQAIEHDECLCYTGIK 927
TVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGT ++ IE+ + T K
Sbjct: 739 TVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATK 798
Query: 928 PSDV 931
DV
Sbjct: 799 MKDV 802
Score = 369 bits (947), Expect = e-102
Identities = 270/638 (42%), Positives = 346/638 (54%), Gaps = 40/638 (6%)
Query: 19 EVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 78
+VSSQKQPA K TSD DSVSN ATEIK+ SGTV + + D+V+ TE
Sbjct: 263 KVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 322
Query: 79 NEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALES 138
+ +S +S K+I + + LL+ + K S
Sbjct: 323 IKEGQQSGTVSPQKQSAWKVIFKKKVS---------------LLNIATRITGGGKSGTVS 367
Query: 139 ENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSP 198
P S+ +++ D+A I TE K+G Q VS
Sbjct: 368 SQKQPP--------SKATSDKTDSALNI-ATEI----------KDGL------QCGTVSS 402
Query: 199 EQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDS 258
++ P T + D +S D S SS++ P T E D A KD
Sbjct: 403 QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDG 462
Query: 259 PPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 318
VSSQKQPA KAT+D++DSVS IATEIK+G SGTVSS+K+PA KATSDEKDS SN
Sbjct: 463 EKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSN 522
Query: 319 IATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATS 378
I E K G+ S TVS QK A K ++ S+L+IA G KS TVSS++ P KAT
Sbjct: 523 ITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATR 582
Query: 379 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 438
D+ DS LNIA K G + VSS KQPALKAT+D+E+SV N+ATE KD + SGTVSSQK
Sbjct: 583 DEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQK 642
Query: 439 QPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEK 498
QPALKAT+D+KDSVSNI TEIKDG++SGTVSSQK A ATS ++ SV +IA E KDG+
Sbjct: 643 QPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQI 702
Query: 499 SRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 558
TVSS+++PA KAT DEKDS SNI R KDGE S VS QK K ++ S+L IA
Sbjct: 703 RGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIA 762
Query: 559 RENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 618
G KS T E P LKA+ + K+SVLN A K + + + + E
Sbjct: 763 TRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKR 822
Query: 619 KDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 656
+ + N + K+ SR + + S++ DS+
Sbjct: 823 LEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 860
Score = 59.3 bits (142), Expect = 2e-08
Identities = 32/43 (74%), Positives = 33/43 (76%)
Query: 836 EQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSP 878
E S VSSQKQPALK TSDK DSVSN TEIKD Q+SGTV P
Sbjct: 14 ETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLP 56
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/88 (42%), Positives = 49/88 (55%)
Query: 805 SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP 864
S VSSQKQPALK DK DSV N ATE KDEQ SGTV + L + + D+V+
Sbjct: 17 SLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPV 76
Query: 865 TEIKDGQQSGTVSPQKQSAQKVIFKKKV 892
TE + +S +S +K+I + +
Sbjct: 77 TEDEFALESEIISKLYIPKRKIISPRSI 104
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 885 bits (2288), Expect = 0.0
Identities = 491/612 (80%), Positives = 515/612 (84%), Gaps = 34/612 (5%)
Query: 298 VSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRI 357
+S QKQPAEKATSDEKDSVSNIATEIK+GQQSGTVSPQKQSA+KVIFKKKVSLLNIATRI
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 358 MGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 417
MGGGKSGTVSSQKQPASK SDKTDSALN ATEIKDGLQCGTVSSQKQ ALKATTDEE S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 418 VSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALT 477
VSNIATEIKDGEKSGTVSSQK+PALKAT+DEKDS SNI E KDGE S TVSSQKPPAL
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 478 ATSDEEGSVLSIARENKDGEKSRTVS---------------------------------- 503
ATS +E SVL+IARE KDGEKSRTVS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 504 SRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 563
SRKKPA KATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 564 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 623
GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 624 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 683
NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
Query: 684 SDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSE 743
SDEKDSVLNIARGKKDGEKTRTVSS+K P LKATSDE+DSVL IARE KDGEKSRTVSS+
Sbjct: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
Query: 744 KPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGE 803
K LKA ++DSV N+A KK + + VSS+K+PALKATSD+KDSV I E KDG+
Sbjct: 572 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 631
Query: 804 KSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNI 863
+S TVSSQKQPA KA K+DSV N+ATE KD QI GTVS QKQ A K KK S+ NI
Sbjct: 632 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNI 691
Query: 864 PTEIKDGQQSGT 875
T I G +SGT
Sbjct: 692 ATRITGGGKSGT 703
Score = 827 bits (2137), Expect = 0.0
Identities = 463/612 (75%), Positives = 485/612 (79%), Gaps = 68/612 (11%)
Query: 366 VSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEI 425
+S QKQPA KATSD+ DS NIATEIK+G Q GTVS QKQ A K ++ S+ NIAT I
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 426 KDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGS 485
G KSGTVSSQKQPA K +D+ DS N ATEIKDG + GTVSSQK AL AT+DEEGS
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 486 VLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLK 545
V +IA E KDGEKS TVSS+KKPA KATSDEKDSFSNITR KKDGEISR VSSQKPP LK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 546 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVS 605
TS +EDSVL IARE KDGEKSRTVS ++PPGLKA+ DEKDS+LNIARGKK GEKT+RVS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 606 SRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKD 665
SRKKP+L+ATSDEKDSFSNITR KKDGEISRKVSSQKPP LKGTSDEEDSVLGIARENKD
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 666 GEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKT---------------------- 703
GEKSRTVSSEKPPGLKA+SDEKDSVLNIARGKK GEKT
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 704 ------------RTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKAT 751
R VSSQKPP LK TSDEEDSVL IARENKDGEKSRTVSSEKP GLKAT
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
Query: 752 SAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 811
S EKDSVLNIARGKK GEKT+ VSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ
Sbjct: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
Query: 812 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 871
KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ
Sbjct: 572 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 631
Query: 872 QS----------------------------------GTVSPQKQSAQKVIFKKKVSLLNI 897
QS GTVSPQKQSAQKVIFKKKVSLLNI
Sbjct: 632 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNI 691
Query: 898 ATRITGGWKSGT 909
ATRITGG KSGT
Sbjct: 692 ATRITGGGKSGT 703
Score = 609 bits (1571), Expect = e-174
Identities = 362/596 (60%), Positives = 419/596 (70%), Gaps = 6/596 (1%)
Query: 170 ENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRD---HISTRFLGGMDSLT 226
E E +V + Q VSP++ K + +I+TR +GG S T
Sbjct: 100 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGT 159
Query: 227 SSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286
S S++ P S + D + A KD G VSSQKQ A KAT+D++ SVSNIA
Sbjct: 160 VS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIA 216
Query: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKK 346
TEIK+G SGTVSSQK+PA KATSDEKDS SNI E K G+ S TVS QK A K K
Sbjct: 217 TEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVK 276
Query: 347 KVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQP 406
+ S+LNIA G KS TVS + P KAT D+ DS LNIA K+G + VSS+K+P
Sbjct: 277 EDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKP 336
Query: 407 ALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSG 466
ALKAT+DE+DS SNI KDGE S VSSQK P LK T+DE+DSV IA E KDGEKS
Sbjct: 337 ALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSR 396
Query: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRG 526
TVSS+KPP L A+SDE+ SVL+IAR K GEK++ VSSRKKP+ +ATSDEKDSFSNITR
Sbjct: 397 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 456
Query: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 586
KKDGEISRKVSSQKPP LKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA+SDEKD
Sbjct: 457 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 516
Query: 587 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
SVLNIARGKK GEKT+ VSSRKKP+L+ATSDEKDS I REKKDGE SR VSSQK PAL
Sbjct: 517 SVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPAL 576
Query: 647 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 706
K D+EDSV +A E KD + S TVSS+K P LKATSD+KDSV NI KDG+++ TV
Sbjct: 577 KAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 636
Query: 707 SSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIA 762
SSQK P KATS ++DSV +IA E KDG+ TVS +K S K +K S+LNIA
Sbjct: 637 SSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIA 692
Score = 505 bits (1300), Expect = e-143
Identities = 299/489 (61%), Positives = 340/489 (69%), Gaps = 34/489 (6%)
Query: 468 VSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGK 527
+S QK PA ATSDE+ SV +IA E K+G++S TVS +K+ A K +K S NI
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 528 KDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDS 587
G S VSSQK P K SD+ DS L A E KDG + TVSS+K LKA++DE+ S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 588 VLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALK 647
V NIA K GEK+ VSS+KKP+L+ATSDEKDSFSNITREKKDGEISR VSSQKPPALK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 648 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVS 707
TS +EDSVL IARE KDGEKSRTVS ++PPGLKAT DEKDS+LNIARGKK+GEKTR VS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 708 S----------------------------------QKPPTLKATSDEEDSVLSIARENKD 733
S QKPPTLK TSDEEDSVL IARENKD
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 734 GEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVL 793
GEKSRTVSSEKP GLKA+S EKDSVLNIARGKKYGEKTKRVSSRKKP+L+ATSDEKDS
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 794 YIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKAT 853
I REKKDGE SR VSSQK PALK D+EDSV +A E KD + S TVSS+K P LKAT
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
Query: 854 SDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTVIRQ 913
SD+KDSV NI KDG+++ TVS +K+ A K +K S+L IA G KS TV Q
Sbjct: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
Query: 914 AIEHDECLC 922
+ +C
Sbjct: 572 KQPALKAIC 580
Score = 433 bits (1114), Expect = e-121
Identities = 299/677 (44%), Positives = 377/677 (55%), Gaps = 46/677 (6%)
Query: 1 MVQILKNAASVFSETT------SLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTV 54
++ +L++ VFS +S QKQPA K TSD+ DSVSN ATEIK+ Q+SGTV
Sbjct: 67 VILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTV 126
Query: 55 LPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEA 114
P + + ++ T +S +S P K S ++
Sbjct: 127 SPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKT----------- 175
Query: 115 VDRCLYLLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNM 174
D T+ K L+ T+S Q + L A E G++
Sbjct: 176 --------DSALNTATEIKDGLQC-----------GTVSSQKQQALKAT----TDEEGSV 212
Query: 175 FEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSER 234
K+G+ + VS ++ P T ++D S D S SS++
Sbjct: 213 SNIATEIKDGE------KSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 266
Query: 235 PPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPI 294
PP T + D A +KD VS + P KAT D+KDS+ NIA K G
Sbjct: 267 PPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEK 326
Query: 295 SGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIA 354
+ VSS+K+PA KATSDEKDS SNI K G+ S VS QK K ++ S+L IA
Sbjct: 327 TRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 386
Query: 355 TRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDE 414
G KS TVSS+K P KA+SD+ DS LNIA K G + VSS+K+P+L+AT+DE
Sbjct: 387 RENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 446
Query: 415 EDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPP 474
+DS SNI E KDGE S VSSQK PALK T+DE+DSV IA E KDGEKS TVSS+KPP
Sbjct: 447 KDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 506
Query: 475 ALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISR 534
L ATSDE+ SVL+IAR KDGEK+RTVSSRKKPA KATSDEKDS I R KKDGE SR
Sbjct: 507 GLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSR 566
Query: 535 KVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARG 594
VSSQK P LK D+EDSV +A E KD + S TVSS+K P LKA+SD+KDSV NI
Sbjct: 567 TVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTE 626
Query: 595 KKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEED 654
K G+++ VSS+K+P+ +ATS +KDS SNI E KDG+I VS QK A K ++
Sbjct: 627 IKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKV 686
Query: 655 SVLGIARENKDGEKSRT 671
S+L IA G KS T
Sbjct: 687 SLLNIATRITGGGKSGT 703
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 610 bits (1574), Expect = e-174
Identities = 352/541 (65%), Positives = 403/541 (74%), Gaps = 13/541 (2%)
Query: 263 KVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 322
++S QKQ AEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE
Sbjct: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
Query: 323 IKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTD 382
IK+GQQSGTVSPQKQSA+KVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASK SDKTD
Sbjct: 82 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 141
Query: 383 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 442
SALN ATEIKDGLQCGTVSSQKQ ALKATTDEE SVSNIATEIKDGEKSGTVSSQK+PAL
Sbjct: 142 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPAL 201
Query: 443 KATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTV 502
KAT+DEKDS SNI E KDGE S TVSSQKPPAL ATS +E SVL+IARE KDGEKSRTV
Sbjct: 202 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTV 261
Query: 503 SSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENK 562
S + P KAT DEKDS NI RGKKDGE +R+VSS K P+LK TSD+EDSV +A E K
Sbjct: 262 SFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETK 321
Query: 563 DGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSF 622
D + S TVS +K P LKA+SD+KDSV NI K G+++ VSS+K+P+ +ATS +KDS
Sbjct: 322 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 381
Query: 623 SNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA 682
SNI E KDG+I VSSQ+ PALK T DE+DSV IARE KDGEKS TVS +K K
Sbjct: 382 SNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKV 441
Query: 683 TSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSS 742
+K S+LNIA G K+ T + TLKAT + +DSVL+ A + K+ + S
Sbjct: 442 IFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTS----- 496
Query: 743 EKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDG 802
T AE+D + +K E+ + + K + + D D + +DG
Sbjct: 497 --------TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 548
Query: 803 E 803
+
Sbjct: 549 D 549
Score = 525 bits (1353), Expect = e-149
Identities = 313/541 (57%), Positives = 368/541 (68%), Gaps = 17/541 (3%)
Query: 332 VSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEI 391
+SPQKQ A K K S+ NIAT I G SGTVSSQKQPA KATSD+ DS NIATEI
Sbjct: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
Query: 392 KDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDS 451
K+G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQKQPA K +D+ DS
Sbjct: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
Query: 452 VSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASK 511
N ATEIKDG + GTVSSQK AL AT+DEEGSV +IA E KDGEKS TVSS+KKPA K
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
Query: 512 ATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVS 571
ATSDEKDSFSNITR KKDGEISR VSSQKPP LK TS +EDSVL IARE KDGEKSRTVS
Sbjct: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262
Query: 572 SEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKD 631
E+PPGLKA+ DEKDS+LNIARGKK GEKT+RVSS K+PSL+ATSD++DS N+ E KD
Sbjct: 263 FEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKD 322
Query: 632 GEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVL 691
+IS VS QK PALK TSD++DSV I E KDG++S TVSS+K P KATS +KDSV
Sbjct: 323 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 382
Query: 692 NIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKAT 751
NIA KDG+ TVSSQ+ P LK T DE+DSV +IARE KDGEKS TVS +K S K
Sbjct: 383 NIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 442
Query: 752 SAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 811
+K S+LNIA G K+ LKAT + KDSVL A + K+ + S
Sbjct: 443 FKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQD 502
Query: 812 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQ--PALKATSDKKDSVSNIPTEIKD 869
+ MA+E + +++ ++Q Q + + D D + + T +D
Sbjct: 503 LE---------------MASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSED 547
Query: 870 G 870
G
Sbjct: 548 G 548
Score = 486 bits (1251), Expect = e-137
Identities = 285/468 (60%), Positives = 337/468 (72%)
Query: 434 VSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIAREN 493
+S QKQ A KAT+D+KDSVSNIATEIK+G SGTVSSQK PA ATSDE+ SV +IA E
Sbjct: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
Query: 494 KDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDS 553
K+G++S TVS +K+ A K +K S NI G S VSSQK P K SD+ DS
Sbjct: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
Query: 554 VLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLE 613
L A E KDG + TVSS+K LKA++DE+ SV NIA K GEK+ VSS+KKP+L+
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
Query: 614 ATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVS 673
ATSDEKDSFSNITREKKDGEISR VSSQKPPALK TS +EDSVL IARE KDGEKSRTVS
Sbjct: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262
Query: 674 SEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKD 733
E+PPGLKAT DEKDS+LNIARGKKDGEKTR VSS K P+LKATSD+EDSV ++A E KD
Sbjct: 263 FEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKD 322
Query: 734 GEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVL 793
+ S TVS +K LKATS +KDSV NI K G+++ VSS+K+PA KATS +KDSV
Sbjct: 323 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 382
Query: 794 YIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKAT 853
IA E KDG+ TVSSQ++PALK D++DSV N+A E KD + SGTVS QKQ A K
Sbjct: 383 NIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 442
Query: 854 SDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 901
KK S+ NI T I G +SGT P+ K + K S+LN AT++
Sbjct: 443 FKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKM 490
Score = 481 bits (1239), Expect = e-135
Identities = 283/471 (60%), Positives = 339/471 (71%), Gaps = 7/471 (1%)
Query: 468 VSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGK 527
+S QK A ATSD++ SV +IA E K+G S TVSS+K+PA KATSDEKDS SNI
Sbjct: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
Query: 528 KDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDS 587
K+G+ S VS QK K ++ S+L IA G KS TVSS+K P K +SD+ DS
Sbjct: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
Query: 588 VLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALK 647
LN A K G + VSS+K+ +L+AT+DE+ S SNI E KDGE S VSSQK PALK
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
Query: 648 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVS 707
TSDE+DS I RE KDGE SRTVSS+KPP LKATS ++DSVLNIAR KKDGEK+RTVS
Sbjct: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262
Query: 708 SQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKY 767
++PP LKAT DE+DS+L+IAR KDGEK+R VSS K LKATS ++DSV N+A K
Sbjct: 263 FEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKD 322
Query: 768 GEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVP 827
+ + VS +K+PALKATSD+KDSV I E KDG++S TVSSQKQPA KA K+DSV
Sbjct: 323 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 382
Query: 828 NMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVI 887
N+ATE KD QI GTVSSQ++PALK T D+KDSVSNI EIKDG++SGTVSPQKQSAQKVI
Sbjct: 383 NIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 442
Query: 888 FKKKVSLLNIATRITGGWKSGT-------VIRQAIEHDECLCYTGIKPSDV 931
FKKKVSLLNIATRITGG KSGT ++ IE+ + + T K +V
Sbjct: 443 FKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEV 493
Score = 451 bits (1161), Expect = e-126
Identities = 280/515 (54%), Positives = 337/515 (65%), Gaps = 4/515 (0%)
Query: 229 EESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATE 288
E S ++ T + D S A K+ P G VSSQKQPAEKATSD+KDSVSNIATE
Sbjct: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
Query: 289 IKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKV 348
IKEG SGTVS QKQ A+K +K S+ NIAT I G +SGTVS QKQ A K K
Sbjct: 82 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 141
Query: 349 SLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPAL 408
S LN AT I G + GTVSSQKQ A KAT+D+ S NIATEIKDG + GTVSSQK+PAL
Sbjct: 142 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPAL 201
Query: 409 KATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTV 468
KAT+DE+DS SNI E KDGE S TVSSQK PALKAT+ ++DSV NIA E KDGEKS TV
Sbjct: 202 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTV 261
Query: 469 SSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKK 528
S ++PP L AT DE+ S+L+IAR KDGEK+R VSS K+P+ KATSD++DS N+ K
Sbjct: 262 SFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETK 321
Query: 529 DGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSV 588
D +IS VS QK P LK TSD++DSV I E KDG++S TVSS+K P KA+S +KDSV
Sbjct: 322 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 381
Query: 589 LNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKG 648
NIA K G+ VSS+++P+L+ T DEKDS SNI RE KDGE S VS QK A K
Sbjct: 382 SNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKV 441
Query: 649 TSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSS 708
++ S+L IA G KS T E LKAT + KDSVLN A K+ +T T +
Sbjct: 442 IFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKE-VQTSTPAE 500
Query: 709 QKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSE 743
Q L+ S+ E L N+ K++ S +
Sbjct: 501 Q---DLEMASEGEQKRLEEYENNQPQVKNQIHSRD 532
Score = 408 bits (1049), Expect = e-113
Identities = 238/379 (62%), Positives = 271/379 (71%)
Query: 535 KVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARG 594
++S QK K TSD++DSV IA E K+G S TVSS+K P KA+SDEKDSV NIA
Sbjct: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
Query: 595 KKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEED 654
K G+++ VS +K+ + + +K S NI G S VSSQK PA K SD+ D
Sbjct: 82 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 141
Query: 655 SVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTL 714
S L A E KDG + TVSS+K LKAT+DE+ SV NIA KDGEK+ TVSSQK P L
Sbjct: 142 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPAL 201
Query: 715 KATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRV 774
KATSDE+DS +I RE KDGE SRTVSS+KP LKATS ++DSVLNIAR KK GEK++ V
Sbjct: 202 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTV 261
Query: 775 SSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKK 834
S + P LKAT DEKDS+L IAR KKDGEK+R VSS KQP+LKA DKEDSVPNMATE K
Sbjct: 262 SFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETK 321
Query: 835 DEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSL 894
DEQISGTVS QKQPALKATSDKKDSVSNIPTEIKDGQQSGTVS QKQ A K KK S+
Sbjct: 322 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 381
Query: 895 LNIATRITGGWKSGTVIRQ 913
NIAT I G GTV Q
Sbjct: 382 SNIATEIKDGQIRGTVSSQ 400
Score = 346 bits (888), Expect = 5e-95
Identities = 230/490 (46%), Positives = 288/490 (58%), Gaps = 6/490 (1%)
Query: 170 ENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRD---HISTRFLGGMDSLT 226
E E +V + Q VSP++ K + +I+TR +GG S T
Sbjct: 65 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGT 124
Query: 227 SSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286
S S++ P S + D + A KD G VSSQKQ A KAT+D++ SVSNIA
Sbjct: 125 VS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIA 181
Query: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKK 346
TEIK+G SGTVSSQK+PA KATSDEKDS SNI E K G+ S TVS QK A K K
Sbjct: 182 TEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVK 241
Query: 347 KVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQP 406
+ S+LNIA G KS TVS ++ P KAT D+ DS LNIA KDG + VSS KQP
Sbjct: 242 EDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQP 301
Query: 407 ALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSG 466
+LKAT+D+EDSV N+ATE KD + SGTVS QKQPALKAT+D+KDSVSNI TEIKDG++SG
Sbjct: 302 SLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSG 361
Query: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRG 526
TVSSQK PA ATS ++ SV +IA E KDG+ TVSS+++PA K T DEKDS SNI R
Sbjct: 362 TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIARE 421
Query: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 586
KDGE S VS QK K ++ S+L IA G KS T E LKA+ + KD
Sbjct: 422 IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKD 481
Query: 587 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
SVLN A K + + + + E + + N + K+ SR +
Sbjct: 482 SVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS 541
Query: 647 KGTSDEEDSV 656
+ S++ DS+
Sbjct: 542 QTVSEDGDSL 551
Score = 260 bits (665), Expect = 4e-69
Identities = 192/452 (42%), Positives = 243/452 (53%), Gaps = 18/452 (3%)
Query: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
VSSQKQPA K TSD+ DSVSN ATEIK+ Q+SGTV P + + ++ T
Sbjct: 57 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 116
Query: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVD--RCLYLLDRFAQPV--TKDKFA 135
+S +S P K S ++ L E D +C + + Q + T D+
Sbjct: 117 MGGGKSGTVSSQKQPASKTASDKT-DSALNTATEIKDGLQCGTVSSQKQQALKATTDEEG 175
Query: 136 LESENISEPYFTNRR--TISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQK 193
S NI+ + T+S Q L A ++ + F + +K+ + T
Sbjct: 176 SVS-NIATEIKDGEKSGTVSSQKKPALKAT-----SDEKDSFSNITREKKDGEISRT--- 226
Query: 194 ANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAM 253
VS ++PP T D + D S S E+PP T E D A
Sbjct: 227 --VSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIAR 284
Query: 254 RRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEK 313
+KD +VSS KQP+ KATSD +DSV N+ATE K+ ISGTVS QKQPA KATSD+K
Sbjct: 285 GKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKK 344
Query: 314 DSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPA 373
DSVSNI TEIK GQQSGTVS QKQ A K KK S+ NIAT I G GTVSSQ++PA
Sbjct: 345 DSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPA 404
Query: 374 SKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGT 433
K T D+ DS NIA EIKDG + GTVS QKQ A K ++ S+ NIAT I G KSGT
Sbjct: 405 LKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 464
Query: 434 VSSQKQPALKATTDEKDSVSNIATEIKDGEKS 465
+ LKAT + KDSV N AT++K+ + S
Sbjct: 465 EYPENLRTLKATIENKDSVLNTATKMKEVQTS 496
Score = 229 bits (585), Expect = 7e-60
Identities = 170/414 (41%), Positives = 214/414 (51%), Gaps = 31/414 (7%)
Query: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQC 61
V +L A + S VSSQKQPA K SDK DS NTATEIKD + GTV +Q
Sbjct: 107 VSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQA 166
Query: 62 LNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPV-EEAVDRCLY 120
L + +V+ TE + +S +S P K S KD + E D
Sbjct: 167 LKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDE--KDSFSNITREKKD---- 220
Query: 121 LLDRFAQPVTKDK-FALESENISEPYFTN----------RRTISQQSAENLDAACGIDKT 169
++ V+ K AL++ ++ E N RT+S + L A +
Sbjct: 221 --GEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKAT----RD 274
Query: 170 ENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSE 229
E ++ K+G+ + VS + P T D + D S
Sbjct: 275 EKDSLLNIARGKKDGE------KTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGT 328
Query: 230 ESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEI 289
S ++ P T + D S KD G VSSQKQPA KATS KDSVSNIATEI
Sbjct: 329 VSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEI 388
Query: 290 KEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVS 349
K+G I GTVSSQ++PA K T DEKDSVSNIA EIK G++SGTVSPQKQSA+KVIFKKKVS
Sbjct: 389 KDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVS 448
Query: 350 LLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQ 403
LLNIATRI GGGKSGT + KAT + DS LN AT++K+ +Q T + Q
Sbjct: 449 LLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKE-VQTSTPAEQ 501
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 605 bits (1560), Expect = e-173
Identities = 327/384 (85%), Positives = 345/384 (89%)
Query: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI
Sbjct: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
Query: 324 KKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383
K+GQQSGTVSPQKQSA KVIFKKKVSLLNIATRI GGGKSGTVSSQKQPASKATSDKTDS
Sbjct: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
Query: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK
Sbjct: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
Query: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503
ATTDE+DSV NIATEIKDGEKS TVSSQK PAL AT+DEE SV IA E KDGEKS TVS
Sbjct: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
Query: 504 SRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 563
SRKKPA KATSDEKDSFSNITR KKDGEISR V+S+KP LK TSDEEDSVL IAR +D
Sbjct: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307
Query: 564 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 623
GEK+R VSS K P LKA+SDEKDS NI R KK GE ++ VSS+K P+L+ATSDE+DS
Sbjct: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367
Query: 624 NITREKKDGEISRKVSSQKPPALK 647
+I RE+KDGE SR VSS++PP LK
Sbjct: 368 SIAREEKDGEKSRTVSSEQPPGLK 391
Score = 525 bits (1353), Expect = e-149
Identities = 291/389 (74%), Positives = 318/389 (81%)
Query: 293 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLN 352
P +VSSQKQPAEKATSD+KDSVSNIATEIK+G SGTVS QKQ A K +K S+ N
Sbjct: 3 PFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 62
Query: 353 IATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
IAT I G +SGTVS QKQ A K K S LNIAT I G + GTVSSQKQPA KAT+
Sbjct: 63 IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATS 122
Query: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK 472
D+ DS NIATEIKDG + GTVSSQKQPALKATTDE+DSVSNIATEIKDGEKSGTVSSQK
Sbjct: 123 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 182
Query: 473 PPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI 532
PAL AT+DEE SVL+IA E KDGEKS TVSS+K+PA KAT+DE+DS S I KDGE
Sbjct: 183 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 242
Query: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA 592
S VSS+K P LK TSDE+DS I RE KDGE SRTV+SEKP GLKA+SDE+DSVLNIA
Sbjct: 243 SGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIA 302
Query: 593 RGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDE 652
RGK+ GEKT+RVSSRKKP+L+ATSDEKDSFSNITREKKDGE SR VSSQKPPALK TSDE
Sbjct: 303 RGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDE 362
Query: 653 EDSVLGIARENKDGEKSRTVSSEKPPGLK 681
EDSVL IARE KDGEKSRTVSSE+PPGLK
Sbjct: 363 EDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
Score = 498 bits (1281), Expect = e-140
Identities = 277/385 (71%), Positives = 307/385 (79%)
Query: 365 TVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 424
+VSSQKQPA KATSD DS NIATEIK+G GTVSSQKQPA KAT+DE+DSVSNIATE
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 425 IKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEG 484
IK+G++SGTVS QKQ A K +K S+ NIAT I G KSGTVSSQK PA ATSD+
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 485 SVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 544
S L+IA E KDG + TVSS+K+PA KAT+DE+DS SNI KDGE S VSSQK P L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 545 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRV 604
K T+DEEDSVL IA E KDGEKS TVSS+K P LKA++DE+DSV IA K GEK+ V
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENK 664
SSRKKP+L+ATSDEKDSFSNITREKKDGEISR V+S+KP LK TSDEEDSVL IAR +
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 665 DGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSV 724
DGEK+R VSS K P LKATSDEKDS NI R KKDGE +RTVSSQKPP LKATSDEEDSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 725 LSIARENKDGEKSRTVSSEKPSGLK 749
LSIARE KDGEKSRTVSSE+P GLK
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391
Score = 451 bits (1161), Expect = e-126
Identities = 259/383 (67%), Positives = 280/383 (73%), Gaps = 34/383 (8%)
Query: 231 SSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIK 290
SS++ P T + D S A K+ P G VSSQKQPAEKATSD+KDSVSNIATEIK
Sbjct: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
Query: 291 EGPISGTVS----------------------------------SQKQPAEKATSDEKDSV 316
EG SGTVS SQKQPA KATSD+ DS
Sbjct: 69 EGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSA 128
Query: 317 SNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKA 376
NIATEIK G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQKQPA KA
Sbjct: 129 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 188
Query: 377 TSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSS 436
T+D+ DS LNIATEIKDG + TVSSQKQPALKATTDEEDSVS IATEIKDGEKSGTVSS
Sbjct: 189 TTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSS 248
Query: 437 QKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDG 496
+K+PALKAT+DEKDS SNI E KDGE S TV+S+KP L ATSDEE SVL+IAR +DG
Sbjct: 249 RKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDG 308
Query: 497 EKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLG 556
EK+R VSSRKKPA KATSDEKDSFSNITR KKDGE SR VSSQKPP LK TSDEEDSVL
Sbjct: 309 EKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLS 368
Query: 557 IARENKDGEKSRTVSSEKPPGLK 579
IARE KDGEKSRTVSSE+PPGLK
Sbjct: 369 IAREEKDGEKSRTVSSEQPPGLK 391
Score = 434 bits (1116), Expect = e-121
Identities = 250/387 (64%), Positives = 290/387 (74%)
Query: 433 TVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARE 492
+VSSQKQPA KAT+D+KDSVSNIATEIK+G SGTVSSQK PA ATSDE+ SV +IA E
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 493 NKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEED 552
K+G++S TVS +K+ A K +K S NI G S VSSQK P K TSD+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 553 SVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSL 612
S L IA E KDG + TVSS+K P LKA++DE+DSV NIA K GEK+ VSS+K+P+L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 613 EATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTV 672
+AT+DE+DS NI E KDGE S VSSQK PALK T+DEEDSV IA E KDGEKS TV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 673 SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENK 732
SS K P LKATSDEKDS NI R KKDGE +RTV+S+KP LKATSDEEDSVL+IAR +
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 733 DGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSV 792
DGEK+R VSS K LKATS EKDS NI R KK GE ++ VSS+K PALKATSDE+DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 793 LYIAREKKDGEKSRTVSSQKQPALKAI 819
L IARE+KDGEKSRTVSS++ P LK +
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLKVM 393
Score = 430 bits (1105), Expect = e-120
Identities = 248/385 (64%), Positives = 290/385 (75%)
Query: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRG 526
+VSSQK PA ATSD++ SV +IA E K+G S TVSS+K+PA KATSDEKDS SNI
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 586
K+G+ S VS QK K ++ S+L IA G KS TVSS+K P KA+SD+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 587 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
S LNIA K G + VSS+K+P+L+AT+DE+DS SNI E KDGE S VSSQK PAL
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 647 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 706
K T+DEEDSVL IA E KDGEKS TVSS+K P LKAT+DE+DSV IA KDGEK+ TV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 707 SSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKK 766
SS+K P LKATSDE+DS +I RE KDGE SRTV+SEKP+GLKATS E+DSVLNIARGK+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 767 YGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSV 826
GEKT+RVSSRKKPALKATSDEKDS I REKKDGE SRTVSSQK PALKA D+EDSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 827 PNMATEKKDEQISGTVSSQKQPALK 851
++A E+KD + S TVSS++ P LK
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391
Score = 405 bits (1042), Expect = e-113
Identities = 236/387 (60%), Positives = 280/387 (72%)
Query: 501 TVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARE 560
+VSS+K+PA KATSD+KDS SNI K+G IS VSSQK P K TSDE+DSV IA E
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 561 NKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKD 620
K+G++S TVS +K K +K S+LNIA G K+ VSS+K+P+ +ATSD+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 621 SFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 680
S NI E KDG VSSQK PALK T+DEEDSV IA E KDGEKS TVSS+K P L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 681 KATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTV 740
KAT+DE+DSVLNIA KDGEK+ TVSSQK P LKAT+DEEDSV IA E KDGEKS TV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 741 SSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKK 800
SS K LKATS EKDS NI R KK GE ++ V+S K LKATSDE+DSVL IAR K+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 801 DGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSV 860
DGEK+R VSS+K+PALKA D++DS N+ EKKD + S TVSSQK PALKATSD++DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 861 SNIPTEIKDGQQSGTVSPQKQSAQKVI 887
+I E KDG++S TVS ++ KV+
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLKVM 393
Score = 364 bits (934), Expect = e-100
Identities = 220/375 (58%), Positives = 260/375 (69%)
Query: 536 VSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGK 595
VSSQK P K TSD++DSV IA E K+G S TVSS+K P KA+SDEKDSV NIA
Sbjct: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
Query: 596 KYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDS 655
K G+++ VS +K+ + + +K S NI G S VSSQK PA K TSD+ DS
Sbjct: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
Query: 656 VLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLK 715
L IA E KDG + TVSS+K P LKAT+DE+DSV NIA KDGEK+ TVSSQK P LK
Sbjct: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
Query: 716 ATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVS 775
AT+DEEDSVL+IA E KDGEKS TVSS+K LKAT+ E+DSV IA K GEK+ VS
Sbjct: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
Query: 776 SRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKD 835
SRKKPALKATSDEKDS I REKKDGE SRTV+S+K LKA D+EDSV N+A K+D
Sbjct: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307
Query: 836 EQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLL 895
+ + VSS+K+PALKATSD+KDS SNI E KDG+ S TVS QK A K ++ S+L
Sbjct: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367
Query: 896 NIATRITGGWKSGTV 910
+IA G KS TV
Sbjct: 368 SIAREEKDGEKSRTV 382
Score = 237 bits (604), Expect = 4e-62
Identities = 177/424 (41%), Positives = 227/424 (53%), Gaps = 40/424 (9%)
Query: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
VSSQKQPA K TSD DSVSN ATEIK+ SGTV + + D+V+ TE
Sbjct: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
Query: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
+ +S +S K+I + + L A +T +S
Sbjct: 68 KEGQQSGTVSPQKQSAWKVIFKKKVS----------------LLNIATRITGGG---KSG 108
Query: 140 NISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPE 199
+S + ++ S+ +++ D+A I TE K+G Q VS +
Sbjct: 109 TVS----SQKQPASKATSDKTDSALNI-ATEI----------KDGL------QCGTVSSQ 147
Query: 200 QPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSP 259
+ P T + D +S D S SS++ P T E D A KD
Sbjct: 148 KQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGE 207
Query: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
VSSQKQPA KAT+D++DSVS IATEIK+G SGTVSS+K+PA KATSDEKDS SNI
Sbjct: 208 KSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNI 267
Query: 320 ATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSD 379
E K G+ S TV+ +K + K ++ S+LNIA G K+ VSS+K+PA KATSD
Sbjct: 268 TREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSD 327
Query: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
+ DS NI E KDG TVSSQK PALKAT+DEEDSV +IA E KDGEKS TVSS++
Sbjct: 328 EKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQP 387
Query: 440 PALK 443
P LK
Sbjct: 388 PGLK 391
Score = 137 bits (345), Expect = 5e-32
Identities = 116/342 (33%), Positives = 156/342 (45%), Gaps = 40/342 (11%)
Query: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQC 61
V +L A + S VSSQKQPA K TSDK DS N ATEIKD + GTV +
Sbjct: 92 VSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPA 151
Query: 62 LNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYL 121
L + D+V+ TE + +S +S P K +
Sbjct: 152 LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE------------------ 193
Query: 122 LDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVD 181
D T+ K +SE T+S Q L A D+ ++ ++ + D
Sbjct: 194 -DSVLNIATEIKDGEKSE-----------TVSSQKQPALKATT--DEEDSVSIIATEIKD 239
Query: 182 KEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLT 241
E + VS + P T ++D S D S +SE+P T
Sbjct: 240 GE--------KSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKAT 291
Query: 242 LKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 301
E D A ++D +VSS+K+PA KATSD+KDS SNI E K+G S TVSSQ
Sbjct: 292 SDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQ 351
Query: 302 KQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVI 343
K PA KATSDE+DSV +IA E K G++S TVS ++ KV+
Sbjct: 352 KPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVM 393
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 267 bits (682), Expect = 4e-71
Identities = 152/234 (64%), Positives = 178/234 (76%), Gaps = 7/234 (2%)
Query: 705 TVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARG 764
+VSS+KP LKATSDE+DSVL+IAR K GEK+R VSS K LKATS +++SV N+A
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 765 KKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKED 824
K + + VSS+K+PALKATSD+KDSV I E KDG++S TVSSQKQPA KA K+D
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 825 SVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQ 884
SV N+ATE KD QI GTVSSQ+QPALKAT D+KDSVSNI EIKDG++SGTVSPQKQSAQ
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 885 KVIFKKKVSLLNIATRITGGWKSGT-------VIRQAIEHDECLCYTGIKPSDV 931
KVIFKKKVSLLNIATRITGGWKSGT ++ IE+ + T K DV
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDV 240
Score = 244 bits (622), Expect = 4e-64
Identities = 150/304 (49%), Positives = 193/304 (63%), Gaps = 17/304 (5%)
Query: 569 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 628
+VSSEKP GLKA+SDEKDSVLNIARGKK+GEKT+RVSS K+P+L+ATSD+++S N+ E
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 629 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 688
KD +IS VSSQK PALK TSD++DSV I E KDG++S TVSS+K P KATS +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 689 SVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGL 748
SV NIA KDG+ TVSSQ+ P LKAT DE+DSV +IARE KDGEKS TVS +K S
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 749 KATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTV 808
K +K S+LNIA G K+ P LKAT + K+SVL A + KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 809 SSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQ--PALKATSDKKDSVSNIPTE 866
+ MA+E + +++ ++Q Q + + D D + + T
Sbjct: 247 EQDLE---------------MASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTV 291
Query: 867 IKDG 870
+DG
Sbjct: 292 SEDG 295
Score = 244 bits (622), Expect = 4e-64
Identities = 148/259 (57%), Positives = 171/259 (66%)
Query: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
VSS+K KATSD+KDSV NIA K G + VSS KQPA KATSD+++SV N+ATE
Sbjct: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
Query: 324 KKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383
K Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQPA KATS K DS
Sbjct: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
Query: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
NIATEIKDG GTVSSQ+QPALKAT DE+DSVSNIA EIKDGEKSGTVS QKQ A K
Sbjct: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
Query: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503
+K S+ NIAT I G KSGT + P L AT + + SVL+ A + KD + S
Sbjct: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247
Query: 504 SRKKPASKATSDEKDSFSN 522
+ AS+ + + N
Sbjct: 248 QDLEMASEGEQKRLEEYEN 266
Score = 233 bits (594), Expect = 6e-61
Identities = 141/241 (58%), Positives = 161/241 (66%)
Query: 293 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLN 352
P +VSS+K KATSDEKDSV NIA K G+++ VS KQ A K K+ S+ N
Sbjct: 3 PFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPN 62
Query: 353 IATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
+AT SGTVSSQKQPA KATSDK DS NI TEIKDG Q GTVSSQKQPA KAT+
Sbjct: 63 MATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATS 122
Query: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK 472
++DSVSNIATEIKDG+ GTVSSQ+QPALKAT DEKDSVSNIA EIKDGEKSGTVS QK
Sbjct: 123 VKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 182
Query: 473 PPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI 532
A ++ S+L+IA G KS T P KAT + K+S N KD +
Sbjct: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 242
Query: 533 S 533
S
Sbjct: 243 S 243
Score = 233 bits (594), Expect = 6e-61
Identities = 137/231 (59%), Positives = 164/231 (70%)
Query: 671 TVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARE 730
+VSSEKP GLKATSDEKDSVLNIARGKK GEKTR VSS K P LKATSD+E+SV ++A E
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 731 NKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKD 790
KD + S TVSS+K LKATS +KDSV NI K G+++ VSS+K+PA KATS +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 791 SVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPAL 850
SV IA E KDG+ TVSSQ+QPALKA D++DSV N+A E KD + SGTVS QKQ A
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 851 KATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 901
K KK S+ NI T I G +SGT P+ K + K S+LN AT++
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKM 237
Score = 229 bits (585), Expect = 7e-60
Identities = 137/237 (57%), Positives = 164/237 (69%)
Query: 331 TVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATE 390
+VS +K S K +K S+LNIA G K+ VSS KQPA KATSDK +S N+ATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 391 IKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKD 450
KD GTVSSQKQPALKAT+D++DSVSNI TEIKDG++SGTVSSQKQPA KAT+ +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 451 SVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPAS 510
SVSNIATEIKDG+ GTVSSQ+ PAL AT DE+ SV +IARE KDGEKS TVS +K+ A
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 511 KATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKS 567
K +K S NI G S + PTLK T + ++SVL A + KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
Score = 229 bits (583), Expect = 1e-59
Identities = 136/236 (57%), Positives = 164/236 (69%)
Query: 638 VSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGK 697
VSS+KP LK TSDE+DSVL IAR K GEK+R VSS K P LKATSD+++SV N+A
Sbjct: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
Query: 698 KDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDS 757
KD + + TVSSQK P LKATSD++DSV +I E KDG++S TVSS+K KATS +KDS
Sbjct: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
Query: 758 VLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALK 817
V NIA K G+ VSS+++PALKAT DEKDSV IARE KDGEKS TVS QKQ A K
Sbjct: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
Query: 818 AICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQS 873
I K+ S+ N+AT SGT + P LKAT + K+SV N T++KD Q S
Sbjct: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
Score = 228 bits (580), Expect = 3e-59
Identities = 144/292 (49%), Positives = 183/292 (62%)
Query: 365 TVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 424
+VSS+K KATSD+ DS LNIA K G + VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 425 IKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEG 484
KD + SGTVSSQKQPALKAT+D+KDSVSNI TEIKDG++SGTVSSQK PA ATS ++
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 485 SVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 544
SV +IA E KDG+ TVSS+++PA KAT DEKDS SNI R KDGE S VS QK
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 545 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRV 604
K ++ S+L IA G KS T E P LKA+ + K+SVLN A K + +
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 656
+ + E + + N + K+ SR + + S++ DS+
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 298
Score = 225 bits (573), Expect = 2e-58
Identities = 135/235 (57%), Positives = 156/235 (66%)
Query: 231 SSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIK 290
SSE+P T E D A +K +VSS KQPA KATSD ++SV N+ATE K
Sbjct: 9 SSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATETK 68
Query: 291 EGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSL 350
+ ISGTVSSQKQPA KATSD+KDSVSNI TEIK GQQSGTVS QKQ A K KK S+
Sbjct: 69 DEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 128
Query: 351 LNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKA 410
NIAT I G GTVSSQ+QPA KAT D+ DS NIA EIKDG + GTVS QKQ A K
Sbjct: 129 SNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKV 188
Query: 411 TTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKS 465
++ S+ NIAT I G KSGT + P LKAT + K+SV N AT++KD + S
Sbjct: 189 IFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
Score = 220 bits (560), Expect = 6e-57
Identities = 140/303 (46%), Positives = 183/303 (60%), Gaps = 13/303 (4%)
Query: 501 TVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARE 560
+VSS K KATSDEKDS NI RGKK GE +R+VSS K P LK TSD+E+SV +A E
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 561 NKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKD 620
KD + S TVSS+K P LKA+SD+KDSV NI K G+++ VSS+K+P+ +ATS +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 621 SFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 680
S SNI E KDG+I VSSQ+ PALK T DE+DSV IARE KDGEKS TVS +K
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 681 KATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTV 740
K +K S+LNIA G K+ T + PTLKAT + ++SVL+ A + KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS--- 243
Query: 741 SSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKK 800
T AE+D + +K E+ + + K + + D D + +
Sbjct: 244 ----------TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSE 293
Query: 801 DGE 803
DG+
Sbjct: 294 DGD 296
Score = 212 bits (539), Expect = 2e-54
Identities = 137/277 (49%), Positives = 174/277 (62%), Gaps = 4/277 (1%)
Query: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRG 526
+VSS+KP L ATSDE+ SVL+IAR K GEK+R VSS K+PA KATSD+++S N+
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 586
KD +IS VSSQK P LK TSD++DSV I E KDG++S TVSS+K P KA+S +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 587 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
SV NIA K G+ VSS+++P+L+AT DEKDS SNI RE KDGE S VS QK A
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 647 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 706
K ++ S+L IA G KS T E P LKAT + K+SVLN A KD +T T
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKD-VQTSTP 245
Query: 707 SSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSE 743
+ Q L+ S+ E L N+ K++ S +
Sbjct: 246 AEQ---DLEMASEGEQKRLEEYENNQPQVKNQIHSRD 279
Score = 198 bits (504), Expect = 2e-50
Identities = 133/303 (43%), Positives = 174/303 (57%), Gaps = 13/303 (4%)
Query: 433 TVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARE 492
+VSS+K LKAT+DEKDSV NIA K GEK+ VSS K PAL ATSD+E SV ++A E
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 493 NKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEED 552
KD + S TVSS+K+PA KATSD+KDS SNI KDG+ S VSSQK P K TS ++D
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 553 SVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSL 612
SV IA E KDG+ TVSS++ P LKA+ DEKDSV NIAR K GEK+ VS +K+ +
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 613 EATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTV 672
+ +K S NI G S + P LK T + ++SVL A + KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS--- 243
Query: 673 SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENK 732
T E+D + +K E+ Q + + D +D + S ++
Sbjct: 244 ----------TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSE 293
Query: 733 DGE 735
DG+
Sbjct: 294 DGD 296
Score = 193 bits (491), Expect = 6e-49
Identities = 117/214 (54%), Positives = 136/214 (63%), Gaps = 2/214 (0%)
Query: 191 GQKAN-VSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSS 249
G+K VS + P T + + D S SS++ P T + D S
Sbjct: 36 GEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVS 95
Query: 250 KAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKAT 309
KD G VSSQKQPA KATS KDSVSNIATEIK+G I GTVSSQ+QPA KAT
Sbjct: 96 NIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKAT 155
Query: 310 SDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQ 369
DEKDSVSNIA EIK G++SGTVSPQKQSA+KVIFKKKVSLLNIATRI GG KSGT +
Sbjct: 156 GDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPE 215
Query: 370 KQPASKATSDKTDSALNIATEIKDGLQCGTVSSQ 403
P KAT + +S LN AT++KD +Q T + Q
Sbjct: 216 NLPTLKATIENKNSVLNTATKMKD-VQTSTPAEQ 248
Score = 192 bits (487), Expect = 2e-48
Identities = 122/267 (45%), Positives = 150/267 (56%)
Query: 195 NVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMR 254
+VS E+P T ++D + G + SS + P T + + A
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 255 RKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKD 314
KD G VSSQKQPA KATSD KDSVSNI TEIK+G SGTVSSQKQPA KATS +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 315 SVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS 374
SVSNIATEIK GQ GTVS Q+Q A K +K S+ NIA I G KSGTVS QKQ A
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
K K S LNIAT I G + GT + P LKAT + ++SV N AT++KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 435 SSQKQPALKATTDEKDSVSNIATEIKD 461
+ A + + N ++K+
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKN 273
Score = 61.6 bits (148), Expect = 3e-09
Identities = 82/306 (26%), Positives = 117/306 (38%), Gaps = 76/306 (24%)
Query: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
VSS KQPALK TSDK++SV N ATE KDEQ SGTV + L + + D+V+ TE
Sbjct: 42 VSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEI 101
Query: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
+ +S +S P K A V KD + +
Sbjct: 102 KDGQQSGTVSSQKQPAWK----------------------------ATSVKKDSVSNIAT 133
Query: 140 NISEPYFTNRRTISQQSAENLDAACGIDKTENGNMF-EDQNVDKEGKALPATGQKANVSP 198
I + R T+S Q L A G +K N+ E ++ +K G P QK +
Sbjct: 134 EIKDGQI--RGTVSSQRQPALKAT-GDEKDSVSNIAREIKDGEKSGTVSP---QKQSA-- 185
Query: 199 EQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDS 258
Q +F V +I+TR GG S T E+
Sbjct: 186 -QKVIFKKKV-SLLNIATRITGGWKSGTEYPEN--------------------------- 216
Query: 259 PPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 318
P KAT ++K+SV N AT++K+ S + A + + N
Sbjct: 217 ----------LPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYEN 266
Query: 319 IATEIK 324
++K
Sbjct: 267 NQPQVK 272
Score = 61.2 bits (147), Expect = 4e-09
Identities = 36/71 (50%), Positives = 42/71 (59%)
Query: 8 AASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLY 67
A E S VSSQKQPALK TSDK DSVSN TEIKD Q+SGTV + +
Sbjct: 64 ATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV 123
Query: 68 RPDAVAQPVTE 78
+ D+V+ TE
Sbjct: 124 KKDSVSNIATE 134
>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 753
Score = 235 bits (600), Expect = 1e-61
Identities = 120/120 (100%), Positives = 120/120 (100%)
Query: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN
Sbjct: 622 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 681
Query: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE
Sbjct: 682 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 741
Score = 116 bits (290), Expect = 1e-25
Identities = 66/115 (57%), Positives = 78/115 (67%)
Query: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEI 459
VSSQKQPALKAT+ +EDS+SNIATEIKDG+KSGTVSSQKQPALK T+D+ DSVSN ATEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 460 KDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATS 514
KD +KSGTV L + +V EN+ +S +S P K S
Sbjct: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 108 bits (271), Expect = 2e-23
Identities = 62/107 (57%), Positives = 74/107 (69%)
Query: 363 SGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIA 422
S VSSQKQPA KATS K DS NIATEIKDG + GTVSSQKQPALK T+D++DSVSN A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 423 TEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVS 469
TEIKD +KSGTV + L + D+V+ TE + +S +S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIIS 691
Score = 103 bits (256), Expect = 1e-21
Identities = 56/74 (75%), Positives = 59/74 (79%)
Query: 805 SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP 864
S VSSQKQPALKA KEDS+ N+ATE KD Q SGTVSSQKQPALK TSDK DSVSN
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 865 TEIKDGQQSGTVSP 878
TEIKD Q+SGTV P
Sbjct: 645 TEIKDEQKSGTVLP 658
Score = 100 bits (249), Expect = 6e-21
Identities = 80/224 (35%), Positives = 116/224 (51%), Gaps = 8/224 (3%)
Query: 675 EKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDG 734
E P L A S K ++ KK + T E+D V+ + + N D
Sbjct: 485 EYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNID- 543
Query: 735 EKSRTVSSEKPSGLKATSAEKDSVLNIA---RGKKYGE---KTKRVSSRKKPALKATSDE 788
SR + K +G A A+ + ++ + K+Y + + VSS+K+PALKATS +
Sbjct: 544 VLSRD-AFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPALKATSGK 602
Query: 789 KDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQP 848
+DS+ IA E KDG+KS TVSSQKQPALK DK+DSV N ATE KDEQ SGTV +
Sbjct: 603 EDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 662
Query: 849 ALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKV 892
L + + D+V+ TE + +S +S +K+I + +
Sbjct: 663 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSI 706
Score = 99.8 bits (247), Expect = 1e-20
Identities = 54/71 (76%), Positives = 59/71 (83%)
Query: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
VSSQKQPA KATS +DS+SNIATEIK+G SGTVSSQKQPA K TSD+ DSVSN ATEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 324 KKGQQSGTVSP 334
K Q+SGTV P
Sbjct: 648 KDEQKSGTVLP 658
Score = 94.4 bits (233), Expect = 5e-19
Identities = 50/72 (69%), Positives = 59/72 (81%)
Query: 431 SGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIA 490
S VSSQKQPALKAT+ ++DS+SNIATEIKDG+KSGTVSSQK PAL TSD++ SV + A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 491 RENKDGEKSRTV 502
E KD +KS TV
Sbjct: 645 TEIKDEQKSGTV 656
Score = 86.3 bits (212), Expect = 1e-16
Identities = 54/93 (58%), Positives = 63/93 (67%), Gaps = 3/93 (3%)
Query: 839 SGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIA 898
S VSSQKQPALKATS K+DS+SNI TEIKDGQ+SGTVS QKQ A K K S+ N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 899 TRITGGWKSGTVIRQAIEHDECLCYTGIKPSDV 931
T I KSGTV+ A+E +CL + +P V
Sbjct: 645 TEIKDEQKSGTVL-PAVE--QCLNRSLYRPDAV 674
Score = 84.3 bits (207), Expect = 5e-16
Identities = 51/107 (47%), Positives = 63/107 (58%)
Query: 635 SRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIA 694
S VSSQK PALK TS +EDS+ IA E KDG+KS TVSS+K P LK TSD+ DSV N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 695 RGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVS 741
KD +K+ TV L + D+V EN+ +S +S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIIS 691
Score = 83.6 bits (205), Expect = 8e-16
Identities = 54/115 (46%), Positives = 64/115 (55%)
Query: 329 SGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIA 388
S VS QKQ A K K+ S+ NIAT I G KSGTVSSQKQPA K TSDK DS N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 389 TEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
TEIKD + GTV + L + D+V+ TE + +S +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 82.4 bits (202), Expect = 2e-15
Identities = 58/139 (41%), Positives = 76/139 (54%), Gaps = 12/139 (8%)
Query: 669 SRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIA 728
S VSS+K P LKATS ++DS+ NIA KDG+K+ TVSSQK P LK TSD++DSV + A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 729 RENKDGEKSRTV----------SSEKPSGLKATSAEKD-SVLNIARGKKYGEKTKRVSSR 777
E KD +KS TV S +P + E + S+ + K Y K K +S R
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
Query: 778 K-KPALKATSDEKDSVLYI 795
K L + D LY+
Sbjct: 705 SIKDVLPPVEEAVDRCLYL 723
Score = 82.4 bits (202), Expect = 2e-15
Identities = 53/115 (46%), Positives = 65/115 (56%)
Query: 295 SGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIA 354
S VSSQKQPA KATS ++DS+SNIATEIK GQ+SGTVS QKQ A K K S+ N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 355 TRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALK 409
T I KSGTV + + + D+ TE + L+ +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 77.4 bits (189), Expect = 6e-14
Identities = 42/69 (60%), Positives = 52/69 (75%)
Query: 604 VSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIAREN 663
VSS+K+P+L+ATS ++DS SNI E KDG+ S VSSQK PALK TSD++DSV A E
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 664 KDGEKSRTV 672
KD +KS TV
Sbjct: 648 KDEQKSGTV 656
Score = 75.9 bits (185), Expect = 2e-13
Identities = 49/118 (41%), Positives = 65/118 (55%)
Query: 499 SRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 558
S VSS+K+PA KATS ++DS SNI KDG+ S VSSQK P LK TSD++DSV A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 559 RENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATS 616
E KD +KS TV L S D+V ++ +++ +S P + S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 74.7 bits (182), Expect = 4e-13
Identities = 51/118 (43%), Positives = 64/118 (54%)
Query: 465 SGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNIT 524
S VSSQK PAL ATS +E S+ +IA E KDG+KS TVSS+K+PA K TSD+ DS SN
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 525 RGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASS 582
KD + S V L + D+V EN+ +S +S P K S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 71.2 bits (173), Expect = 4e-12
Identities = 47/115 (40%), Positives = 61/115 (53%)
Query: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA 592
S VSSQK P LK TS +EDS+ IA E KDG+KS TVSS+K P LK +SD+ DSV N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 593 RGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALK 647
K +K+ V + L + D+ + E + S +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 69.3 bits (168), Expect = 2e-11
Identities = 46/118 (38%), Positives = 64/118 (54%)
Query: 567 SRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNIT 626
S VSS+K P LKA+S ++DS+ NIA K G+K+ VSS+K+P+L+ TSD+ DS SN
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 627 REKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATS 684
E KD + S V L + D+V EN+ +S +S P K S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 68.6 bits (166), Expect = 3e-11
Identities = 46/124 (37%), Positives = 62/124 (50%)
Query: 225 LTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSN 284
+ S+ SS++ P T + D S A KD G VSSQKQPA K TSD DSVSN
Sbjct: 583 INSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSN 642
Query: 285 IATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIF 344
ATEIK+ SGTV + + D+V+ TE + +S +S RK+I
Sbjct: 643 TATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Query: 345 KKKV 348
+ +
Sbjct: 703 PRSI 706
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 87.0 bits (214), Expect = 7e-17
Identities = 132/606 (21%), Positives = 225/606 (37%), Gaps = 79/606 (13%)
Query: 205 THTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKV 264
T V + + + G + EE +E T ++ P+ +AA K++ P K
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEET----KSPPAEEAASPEKEAKSPVKE 522
Query: 265 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 324
+ K PAE + + +++ S + E S K P E A S EK+ + A E+K
Sbjct: 523 EA-KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE-AKSPEKEEAKSPA-EVK 579
Query: 325 KGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSA 384
+++ SP K+ A+ ++ + K P + ++
Sbjct: 580 SPEKA--KSPAKEEAK------------------SPAEAKSPEKAKSPVKEEAKSPAEAK 619
Query: 385 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 444
+ E K + + K P + E + S E K EK+ K P
Sbjct: 620 SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA------KSPVKAE 673
Query: 445 TTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRT-VS 503
+ + S + E K EK+ K P E + + E K EK+++ V
Sbjct: 674 AKSPEKAKSPVKAEAKSPEKA------KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 504 SRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDE----------EDS 553
K KA S K+ + + K + K K P K + E E +
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEK--AKTLDVKSPEAKTPAKEEARSPADKFPEKA 785
Query: 554 VLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGK------KYGEKTKRVSSR 607
+ E K EK+++ E + +K+ V + + + K E K+
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 608 KKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGE 667
K P+ T ++KDS +K+ + KV +K PA++ +E V E +D +
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPK--PKVEEKKEPAVE--KPKESKVEAKKEEAEDKK 901
Query: 668 KSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDS-VLS 726
K T E P ++ D K EKT V+ ++P KA + +
Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPK-----------EKTE-VAKKEPDDAKAKEPSKPAEKKE 949
Query: 727 IARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSR----KKPAL 782
A E KD ++ + E+ +A + E D L+ K EK ++ SS KP
Sbjct: 950 AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009
Query: 783 KATSDE 788
KAT D+
Sbjct: 1010 KATEDK 1015
Score = 83.6 bits (205), Expect = 8e-16
Identities = 127/637 (19%), Positives = 226/637 (35%), Gaps = 87/637 (13%)
Query: 242 LKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 301
+K + S K + ++ +V+ + E+ + +++ E +E G ++
Sbjct: 444 IKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE-GGEEETK 502
Query: 302 KQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGG 361
PAE+A S EK++ S + E K ++ SP+K+ A+ K
Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEAK--SPEKEEAKSPAEVK--------------- 545
Query: 362 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 421
+ K PA + ++ E K + + K PA +E++ S
Sbjct: 546 ---SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA------KEEAKSPA 596
Query: 422 ATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSD 481
+ + KS K PA + ++++ S + + KS T K P + +
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 482 EEGSVLSIARENKDGEKSRT-VSSRKKPASKATSDEKDSFSNITRGKKD-GEISRKVSSQ 539
+E E K EK+++ V + K KA S K + + K E ++
Sbjct: 657 KE--------EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708
Query: 540 KPPTLKGTSDEEDSVLGIARENKDGEKSRT-VSSEKPPGLKASSDEKDSVLNIARGKKYG 598
K P + E + + E K EK+++ V E KA S EK L++
Sbjct: 709 KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV------- 761
Query: 599 EKTKRVSSRKKPSLEATSDEKDSFSNITRE--KKDGEISRKVSSQKPPALKGTSDEEDSV 656
+ K P+ E D F + K++ + K S K E
Sbjct: 762 ----KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK 817
Query: 657 LGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKA 716
+ K+ EK + V ++PP K +EK KKD +K + P
Sbjct: 818 EEVKSPVKEEEKPQEVKVKEPP--KKAEEEKAPATPKTEEKKDSKKEEAPKKEAP----- 870
Query: 717 TSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSS 776
+ + +K V K S ++A E + + +K V
Sbjct: 871 ------------KPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKE 918
Query: 777 RKKPALKATSDEKD-------------SVLYIAREKKDGEKSRTVSSQKQPALKAICDKE 823
KP K +K+ A EKKD ++ + +++P +A ++
Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED 978
Query: 824 DSV----PNMATEKKDEQISGTVSSQKQPALKATSDK 856
D P+ +K E+ S T +P KAT DK
Sbjct: 979 DKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015
Score = 75.1 bits (183), Expect = 3e-13
Identities = 118/510 (23%), Positives = 192/510 (37%), Gaps = 35/510 (6%)
Query: 398 GTVSSQKQPALKATTDEEDSVSNIATEIKDGE--KSGTVSSQKQPALKATTDEKDSVSNI 455
G ++ PA +A + E+++ S + E K KS K PA + ++ S +
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556
Query: 456 ATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSD 515
+ KS K PA + ++ S E K ++++ K P +
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAK--EEAKSPAEAKSPEKAKSPVKEEAKS 614
Query: 516 EKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRT-VSSEK 574
++ S + K + K PT + E + E K EK+++ V +E
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674
Query: 575 PPGLKASSDEKDSVLNIARGKK-YGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGE 633
KA S K + + K E+ K K P E + + S + E K E
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734
Query: 634 ISRK-VSSQKPPALKGTSDEEDSVLGI-ARENKDGEKSRTVSSEKPPGLKATSDEKDSVL 691
++ V + K S E+ L + + E K K S KA S K+ V
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK 794
Query: 692 NIARGK---KDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGL 748
+ + K K+ K K +K+ EE+ +E K E + EK
Sbjct: 795 SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK----PQEVKVKEPPKKAEEEKAPAT 850
Query: 749 KATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTV 808
T +KDS A KK K K V +K+PA++ + K + +K++ E + V
Sbjct: 851 PKTEEKKDSKKEEAP-KKEAPKPK-VEEKKEPAVEKPKESK-----VEAKKEEAEDKKKV 903
Query: 809 SSQKQPALKAICDKEDSVPNMATE-KKDEQISGTVSSQKQPALK--ATSDKKDSVSNIP- 864
+ ++ A + KED+ P TE K E +PA K A +KKD+
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAK 963
Query: 865 -------TEIKDGQQSGTVS--PQKQSAQK 885
TE K + T+S P K A+K
Sbjct: 964 KPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993
Score = 72.0 bits (175), Expect = 2e-12
Identities = 116/529 (21%), Positives = 195/529 (36%), Gaps = 54/529 (10%)
Query: 402 SQKQPALKATTDEEDSVSNIATEIKDGE-----------------KSGTVSSQKQPALKA 444
S+K+ + EE V+ TE ++ E + G ++ PA +A
Sbjct: 450 SEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEA 509
Query: 445 TTDEKDSVSNIATEIKDGE--KSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTV 502
+ EK++ S + E K KS K PA + ++ S ++ KS
Sbjct: 510 ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK 569
Query: 503 SSRKKPAS-----KATSDEKDSFSNITRGKKDGEISRKVSSQ-KPPTLKGTSDEEDSVLG 556
K PA KA S K+ + K + V + K P + +E++
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629
Query: 557 IARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKK-YGEKTKRVSSRKKP-SLEA 614
++ + KS T K P KA S EK+ + + K + K K P EA
Sbjct: 630 AEVKSPEKAKSPTKEEAKSPE-KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688
Query: 615 TSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRT-VS 673
S EK S + E K E K P + E + + E K EK+++ V
Sbjct: 689 KSPEKAK-SPVKEEAKSPE------KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741
Query: 674 SEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKD 733
E KA S EK L++ K KT + P A E + + E K
Sbjct: 742 EEAKSPEKAKSPEKAKTLDV---KSPEAKTPAKEEARSP---ADKFPEKAKSPVKEEVKS 795
Query: 734 GEKSRTVSSEKPSGLKATSAEKDSVLNIARGK------KYGEKTKRVSSRKKPALKATSD 787
EK+++ E + +K+ V + + + K E K+ K PA T +
Sbjct: 796 PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855
Query: 788 EKDSVLYIAREKK------DGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGT 841
+KDS A +K+ + +K V K+ ++A ++ + + T +K+
Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVE 915
Query: 842 VSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKK 890
V +P K KK+ E + +P+K+ ++ KK
Sbjct: 916 VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKK 964
Score = 65.9 bits (159), Expect = 2e-10
Identities = 157/799 (19%), Positives = 288/799 (36%), Gaps = 103/799 (12%)
Query: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
L DRFA + K + LE+ N R++ ++A G ++ G ++E +
Sbjct: 104 LNDRFAGYIDKVR-QLEAHN---------RSLEGEAAALRQQQAG--RSAMGELYEREVR 151
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
+ G L + + EQ H ++D H+ R +E+ +R
Sbjct: 152 EMRGAVLRLGAARGQLRLEQE----HLLEDIAHVRQRL---------DDEARQR------ 192
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKE--GPISGTV 298
+EA+ +++A R +V QK+ A+ + + E+ E G I G+
Sbjct: 193 --EEAEAAARALARFAQEAEAARVDLQKK-AQALQEECGYLRRHHQEEVGELLGQIQGSG 249
Query: 299 SSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAR--KVIFKKKVSLLNIATR 356
++Q Q + K V++ EI+ + V QS +V + + T
Sbjct: 250 AAQAQMQAETRDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAAKVNTD 309
Query: 357 IMGGGKSGTVSSQKQPASKATS-----DKTDSALNIATEIKDGLQCGTVSSQK------- 404
M + ++Q ++ T DS +E++D Q S Q+
Sbjct: 310 AMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDA 369
Query: 405 -----QPALKATTDEEDSVSNI--ATEIKDGEKSGTVSSQK-----QPALKATTDEKDSV 452
+ + A E + N+ A +I+ + ++ P + + +
Sbjct: 370 ELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKI 429
Query: 453 SNIAT--EIKDGEKSGTV-SSQKPPALTATSDEEGSVLSIARENKDGE------------ 497
+++T ++K EK V S+K + EE V E ++ E
Sbjct: 430 PSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGG 489
Query: 498 -----KSRTVSSRKKPASKATSDEKDSFSNITRGKK---DGEISRKVSSQKPPTLKGTSD 549
+ ++ PA +A S EK++ S + K + + K ++ P +K
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK 549
Query: 550 EEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKK 609
+ A+ + + ++ P +K+ K A K + K K
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA---KSPAEAKSPEKAKS 606
Query: 610 PSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKS 669
P E ++ S + E K + K P + E + E K EK+
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 670 RT-VSSEKPPGLKATSDEKDSVLNIARGKKD-GEKTRTVSSQKPPTLKATSDEEDSVLSI 727
++ V +E KA S K + + K E+ ++ K P + E + +
Sbjct: 667 KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV 726
Query: 728 ARENKDGEKSRT-VSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATS 786
E K EK+++ V E S KA S EK L++ K KT + PA K
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV---KSPEAKTPAKEEARSPADKFPE 783
Query: 787 DEKDSVLYIAREKKDGEKSRT-VSSQKQPALKAICDKEDSVPNMATEKKDEQIS-----G 840
K V E K EK+++ + + K I KE+ + E+K +++
Sbjct: 784 KAKSPV---KEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPK 840
Query: 841 TVSSQKQPALKATSDKKDS 859
+K PA T +KKDS
Sbjct: 841 KAEEEKAPATPKTEEKKDS 859
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 78.2 bits (191), Expect = 3e-14
Identities = 138/636 (21%), Positives = 242/636 (38%), Gaps = 95/636 (14%)
Query: 294 ISGTVSSQKQPAEKATSD----EKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVS 349
+S +SS+ + + D E D EI K + P+++ KV K+K
Sbjct: 110 LSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEK 169
Query: 350 LLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALK 409
GK V +++P KAT + E K+ + T++ +++ A
Sbjct: 170 -----------GKE-KVREKEKPEKKATHKEK-------IEKKEKPETKTLAKEQKKAKT 210
Query: 410 ATTDEE-----------DSVSNIATEIKDGEKSGTVSSQKQPALKATT---DEKDSVSNI 455
A EE + V A ++K+ +K+ + +K+ KA ++KD +
Sbjct: 211 AEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFC 270
Query: 456 ATEIK---DGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKA 512
I G+ S PP L + S A E K+GEK KK K
Sbjct: 271 RYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEK-------KKAEKKV 323
Query: 513 TSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSS 572
TS+ K + K + E + V ++P T + A KD +K + +
Sbjct: 324 TSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKT 383
Query: 573 EKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLE-ATSDEKDSFSNITREKKD 631
+KP ++ +GKK +K K V K P E + +K + R K++
Sbjct: 384 KKPAEVEQ-----------PKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEE 432
Query: 632 -GEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSV 690
G +S K + K T E + R+ K G+ S + ++P +K ++ +
Sbjct: 433 IGAVSIKKAVPGKKEEKTTKTVEQEI----RKEKSGKTSSILKDKEP--IKGKEEKVPAS 486
Query: 691 L--NIARGKKDGEKTRTVS--SQKPPTLKATSDEEDSVLSIARENKDG------------ 734
L KKD + ++ KPP L+ +E+ I +E K
Sbjct: 487 LKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEP-QIKKEAKPAISEKVQIHKQDI 545
Query: 735 -EKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVL 793
+ +TVS KP + ++ A+ K TK+ R++ +D+
Sbjct: 546 VKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPK----PTKKAEHREREPPSIKTDKPKPTP 601
Query: 794 YIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKAT 853
E + K +T S+K+ KA K ++T K+ Q+ ++K PA + +
Sbjct: 602 KGTSEVTESGKKKTEISEKESKEKADM-KHLREEKVSTRKESLQLHNVTKAEK-PA-RVS 658
Query: 854 SDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFK 889
D V ++P K + + VSP KQ + F+
Sbjct: 659 KD----VEDVPASKKAKEGTEDVSPTKQKSPISFFQ 690
Score = 32.3 bits (72), Expect = 2.2
Identities = 46/209 (22%), Positives = 85/209 (40%), Gaps = 18/209 (8%)
Query: 241 TLKEADPS-------SKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGP 293
+LKE +P SKA K PP + +++P + + K ++S K+
Sbjct: 486 SLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDI 545
Query: 294 I--SGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLL 351
+ TVS K P EK K + + K + + +++ + K
Sbjct: 546 VKPEKTVSHGK-PEEKVLKQVK---AVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTP 601
Query: 352 NIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKAT 411
+ + GK T S+K+ SK +D + K+ LQ V+ ++PA + +
Sbjct: 602 KGTSEVTESGKKKTEISEKE--SKEKADMKHLREEKVSTRKESLQLHNVTKAEKPA-RVS 658
Query: 412 TDEEDSVSNIATEIKDGEKSGTVSSQKQP 440
D ED + + + K+G + + + QK P
Sbjct: 659 KDVEDVPA--SKKAKEGTEDVSPTKQKSP 685
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 76.3 bits (186), Expect = 1e-13
Identities = 124/719 (17%), Positives = 236/719 (32%), Gaps = 27/719 (3%)
Query: 171 NGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEE 230
NGN D++ +GK+ + ++ S + D S+ DS SS+
Sbjct: 532 NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS-DSSDS 590
Query: 231 SSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDK----DSVSNIA 286
S S+ + +D S + K S K ++ + SD K DS S+ +
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS 650
Query: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKK 346
++ + S S+ ++ + S + S S+ + S + + + S
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710
Query: 347 KVSLLNIATRIMGGGKSGTVSSQKQPASKA--TSDKTDSALNIATEIKDGLQCGTVSSQK 404
S + ++ + SS +S + +SD +DS+ + + + SS
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 405 QPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEK 464
+ ++ S SN ++ D S S + ++D DS + ++ D
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS--DSSDSSDSSDSDSSNSSDSSN 828
Query: 465 SGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNIT 524
S S + ++ S + N+ + + SS +S ++ S SN +
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Query: 525 RGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDE 584
D S S +SD DS + + E S + + SSD
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDS----SNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 585 KDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPP 644
DS + SS S + S + + S+ + + S S
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004
Query: 645 ALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTR 704
+SD DS N + + SS+ +SD DS +
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS----SDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 705 TVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARG 764
+ SS + ++ + S S + ++ D S S S + S++ + +
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 765 KKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKED 824
+ + S +SD DS E D S S + D D
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDS-----SESSDSSDSSDSSDSSDSS-----DSSD 1170
Query: 825 SVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSA 883
S + + + + SS + ++ S S+ ++ D S S S+
Sbjct: 1171 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Score = 66.6 bits (161), Expect = 1e-10
Identities = 98/512 (19%), Positives = 172/512 (33%), Gaps = 35/512 (6%)
Query: 377 TSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGE-KSGTVS 435
+S + D++ N + E KD G S K A D+ DS S+ +G +G
Sbjct: 485 SSSRGDASYN-SDESKDN---GNGSDSKG----AEDDDSDSTSDTNNSDSNGNGNNGNDD 536
Query: 436 SQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTAT--SDEEGSVLSIAREN 493
+ K + K +D DS S+ ++ D S S + + + SD + S S + +
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596
Query: 494 KDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDS 553
S + S S +SD DS S+ ++ + D S S +SD DS
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656
Query: 554 VLGIARENKDGEKSRTVSSEKPPGLKA--SSDEKDSVLNIARGKKYGEKTKRVSSRKKPS 611
N + SS+ + SSD DS + S S
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS-----------SDSSNSSESSDSS 705
Query: 612 LEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRT 671
+ SD DS + D + S S +SD DS + + + S +
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS----SNSSDSSDSSDS 761
Query: 672 VSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIAREN 731
+S +SD DS + + + + S +S+ DS S +
Sbjct: 762 SNSSDSSDSSDSSDSSDS----SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Query: 732 KDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDS 791
D S S+ S + S++ + + G + SS + ++ S
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 792 VLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALK 851
+ + D +S S + + D DS + + + SS
Sbjct: 878 ---DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934
Query: 852 ATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSA 883
++ S S+ ++ + S S S+
Sbjct: 935 SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Score = 65.9 bits (159), Expect = 2e-10
Identities = 125/654 (19%), Positives = 227/654 (34%), Gaps = 36/654 (5%)
Query: 137 ESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANV 196
+S N S+ ++ + S +S+++ D++ D +++ + + D + + +N
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDS-DSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740
Query: 197 SPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRK 256
S + D S+ DS SS+ S ++ ++ SS ++
Sbjct: 741 SDSSDSSDSSNSSDSSD-SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS---- 795
Query: 257 DSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV 316
DS S+ ++ + S D DS SN + S + +S +SD DS
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDS-SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 317 SNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKA 376
S+ ++ S S S+ S N ++ S S S
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDS----SDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910
Query: 377 TSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSS 436
+SD +DS+ + + SS + ++ + S S+ ++ D S S+
Sbjct: 911 SSDSSDSSNSSDSSESSN------SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964
Query: 437 QKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDG 496
+ ++D DS SN + + S + S + +SD S + +
Sbjct: 965 SSDSSDSNSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS----SDSSNSS 1019
Query: 497 EKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLG 556
+ S + S S +SD DS S+ + + S S +SD DS
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS--- 1075
Query: 557 IARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATS 616
+ + E S + S SSD DS + + + + +S +S
Sbjct: 1076 -SDSSDSSESSDSSDSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Query: 617 DEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEK 676
D DS SN + E S S +SD DS N + SS+
Sbjct: 1134 DSSDS-SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 677 PPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEK 736
+SD DS + + SS + ++ E S S + ++ D
Sbjct: 1193 ----SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248
Query: 737 S--RTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDE 788
S + SS+ ++ E DS G G + S + +TSD+
Sbjct: 1249 SSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS-DSEGSDSNHSTSDD 1301
Score = 63.9 bits (154), Expect = 7e-10
Identities = 102/546 (18%), Positives = 172/546 (31%), Gaps = 57/546 (10%)
Query: 359 GGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSV 418
G G +G + K + K SD +DS + ++ D ++D DS
Sbjct: 528 GNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD-----------------SSDSSDSD 570
Query: 419 SNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPA--- 475
S+ + D + S + SS D DS S+ ++ D S S +
Sbjct: 571 SSDSNSSSDSDSSDSDSS----------DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS 620
Query: 476 ---------------LTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSF 520
+ SD S S + +N D S S+ + + S + S
Sbjct: 621 DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 521 SNITRG--KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 578
S+ + D S S + SD DS + D + S + S
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740
Query: 579 KASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV 638
SSD DS + SS S +++ S SN + D S
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800
Query: 639 SSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVS-SEKPPGLKATSDEKDSVLNIARGK 697
S + +SD DS + + D S S S +SD D + + +
Sbjct: 801 SDSSNSS--DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858
Query: 698 KDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDS 757
D + S + +SD DS S N + SS+ S + S++
Sbjct: 859 SDSSNSSDSSDSSDSS--NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916
Query: 758 VLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALK 817
N + + + +S +SD DS D S S+ +
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS-----SNSSDSSNSSDSSNSSDSSDS 971
Query: 818 AICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVS 877
D DS + + + + SS + ++ S S+ ++ + S S
Sbjct: 972 NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Query: 878 PQKQSA 883
S+
Sbjct: 1032 DSSDSS 1037
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 75.9 bits (185), Expect = 2e-13
Identities = 128/592 (21%), Positives = 218/592 (36%), Gaps = 83/592 (14%)
Query: 223 DSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKD-SPPPGKVSSQ--KQPAEKATSDDK 279
DS SSEE E + P+ KAA+ K PPGK +++ + + + +SDD
Sbjct: 86 DSEDSSEEEEE---------VQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDD 136
Query: 280 DSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSA 339
D +++G + + K P +KA S + DS S+ E K Q+ ++P A
Sbjct: 137 DEEDQKKQPVQKG-VKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKP-KITPVTVKA 194
Query: 340 RKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGT 399
+ K A +I G SS +S ++SD ++ AT K +
Sbjct: 195 QT---KAPPKPARAAPKIANG---KAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV 248
Query: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEI 459
V+ K P ATT S S+ + S QK+P
Sbjct: 249 VA--KAPVKAATTPTRKSSSS------EDSSSDEEEEQKKPM------------------ 282
Query: 460 KDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDS 519
K G SS PP+ G+ K EK + V S S+ +SDE DS
Sbjct: 283 --KNKPGPYSSVPPPSAPPPKKSLGT----QPPKKAVEKQQPVES-----SEDSSDESDS 331
Query: 520 FSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 579
S + + K +++ PP K DS + E+ D S+ + K K
Sbjct: 332 SSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSED-DEAPSKPAGTTKNSSNK 390
Query: 580 ASSDEKDSVLNIARGKKY----GEK--TKRVSSRKKPSLEATSDEKDSFSNITREKKDGE 633
+ K + A K G+K T++ S ++S+E+ + + K
Sbjct: 391 PAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKAT 450
Query: 634 ISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL------------- 680
+S A +G+ D + E ++ + S++ +KP +
Sbjct: 451 AKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAK 510
Query: 681 KATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKA------TSDEEDSVLSIARENKDG 734
K ++ +S + +++ EK + S +P KA T+ + + E ++
Sbjct: 511 KGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEK 570
Query: 735 EKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATS 786
+K+ V S+ S K E + KK +T ++K K S
Sbjct: 571 KKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRAS 622
Score = 73.6 bits (179), Expect = 8e-13
Identities = 134/659 (20%), Positives = 247/659 (37%), Gaps = 104/659 (15%)
Query: 263 KVSSQKQPAEKATSDDKDSVSNI--------ATEIKEGPISGTVSSQKQPAEKATSDEKD 314
+V+++ A AT D ++ S + + ++ E + K+ +KA+S + +
Sbjct: 29 EVANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSE 88
Query: 315 SVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS 374
S E++ P K++A + K+V L GK+ +S+ +S
Sbjct: 89 DSSEEEEEVQG-------PPAKKAA---VPAKRVGL--------PPGKAAAKASESS-SS 129
Query: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
+ +SD D ++ G++ + K P KA + + DS S+ E +K
Sbjct: 130 EESSDDDDEEDQKKQPVQKGVK-PQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKIT 188
Query: 435 SSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENK 494
+KA T + A +I +G+ + + SS + + S+EE + A K
Sbjct: 189 PV----TVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAA---ATPKK 241
Query: 495 DGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSV 554
K + V+ K P AT+ + S S+ +D + +KP
Sbjct: 242 TVPKKQVVA--KAPVKAATTPTRKSSSS-----EDSSSDEEEEQKKP------------- 281
Query: 555 LGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEA 614
+NK G S PP K+ L KK EK + V S E
Sbjct: 282 ----MKNKPGPYSSVPPPSAPPPKKS--------LGTQPPKKAVEKQQPVESS-----ED 324
Query: 615 TSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSS 674
+SDE DS S ++ + K +++ PPA K DS + E+ + ++
Sbjct: 325 SSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTT 384
Query: 675 EKPPGLKATSDEKDSVLNIARGKK---DGEK--TRTVSSQKPPTLKATSDEEDSVLSIAR 729
+ A + + +V A K+ G+K TR S ++S+EE + +A
Sbjct: 385 KNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVAT 444
Query: 730 ENKDGEKSRTVS---SEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKP------ 780
+S + P G + +S++ DS + ++ EKT + + +KKP
Sbjct: 445 TKPKATAKAALSLPAKQAPQGSRDSSSDSDS----SSSEEEEEKTSKSAVKKKPQKVAGG 500
Query: 781 -------------ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVP 827
A + S D EK G+ S + K A+ +
Sbjct: 501 AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAA 560
Query: 828 NMATEKKDEQISGTVSSQKQPALKATSDKKDS-VSNIPTEIKDGQQSGTVSPQKQSAQK 885
+ E+++E+ V K +LK + + + P K Q+ P+++ +K
Sbjct: 561 KNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEK 619
Score = 50.4 bits (119), Expect = 8e-06
Identities = 86/393 (21%), Positives = 146/393 (37%), Gaps = 52/393 (13%)
Query: 227 SSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286
SSE+SS+ S + +E P +KA + + + PP PA+KA DS + +
Sbjct: 321 SSEDSSDESDSS--SEEEKKPPTKAVVSKATTKPP--------PAKKAAESSSDSSDSDS 370
Query: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQ--SARKVIF 344
+E E P K K+S + A K +P++ +K++
Sbjct: 371 SEDDEAP------------SKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLT 418
Query: 345 KKKVSLLNIATRIMGGGKSGTVSSQKQPASK---ATSDKTDSALNIATEIKDGLQCGTVS 401
+K S + + SS+++ K T K + ++ K Q G+
Sbjct: 419 RKADS---------SSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ-GSRD 468
Query: 402 SQKQPALKATTDEEDSVSNIATEIKDGE-KSGTVSSQKQPALKATTDEKDSVSNIATEIK 460
S ++ +EE+ S A + K + G S+ A K + +S S+ + +
Sbjct: 469 SSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEE 528
Query: 461 DGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDE---K 517
+ EK S +P A A G+ A+ K + S KK A+ S K
Sbjct: 529 EEEKLKGKGSPRPQAPKA----NGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLK 584
Query: 518 DSFSNITRGKKDGEISRKVSSQKP---PTLKGTSDEEDSVLGIARENKDGEKSRTVSSEK 574
N + + ++K+ Q P P K S RE + SR +
Sbjct: 585 KRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSF 644
Query: 575 PPGLKASSD---EKDSVLNIARGKKY-GEKTKR 603
A+ D + VL +GK + EKTK+
Sbjct: 645 DAKRGAAGDWGERANQVLKFTKGKSFRHEKTKK 677
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 75.1 bits (183), Expect = 3e-13
Identities = 161/790 (20%), Positives = 292/790 (36%), Gaps = 107/790 (13%)
Query: 125 FAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEG 184
F P D + E + T + + E DKT+ N + KE
Sbjct: 941 FVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVS-KKEN 999
Query: 185 KALPATG--QKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTL 242
PA G +K + E+ P +K + + T S SS++ T T
Sbjct: 1000 IVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPK-----TDNTKSSSSSQKDEKITGTP 1054
Query: 243 KEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEG--PISGTVSS 300
++A SK+A +++ P + +K ++ S+ + A + E P+
Sbjct: 1055 RKAH--SKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK 1112
Query: 301 QKQPAEKATSDEKDSVSNI------ATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIA 354
+K+ E+ D+ S++ TEI K + P + + K K+SL A
Sbjct: 1113 RKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPA 1172
Query: 355 TRIMGGGKSGTV--SSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
+I ++G S++ +K S+K +S ++++K G V + T
Sbjct: 1173 KKIKLNRETGKKIGSTENISNTKEPSEKLEST---SSKVKQEKVKGKVR-------RKVT 1222
Query: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK 472
E S S + + + T S+ P K+ ++ D+ + +++ T ++
Sbjct: 1223 GTEGSSSTLV------DYTSTSSTGGSPVRKSE-EKTDTKRTVIKTMEEYNNDNTAPAED 1275
Query: 473 PPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI 532
+ + E +D + ++ +SS KPAS + + + +K+ E
Sbjct: 1276 VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP 1335
Query: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA 592
S K+ K T D + I E K + S SSEK + D SVL
Sbjct: 1336 SEKIQ-------KFTKDVSHEI--IQHEVKSSKNS--ASSEK----GKTKDRDYSVLE-- 1378
Query: 593 RGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDE 652
K+ EK K + +K S +E+ +F ++++ K+ S K S + + K +
Sbjct: 1379 --KENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPN 1436
Query: 653 EDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPP 712
D K R +E + S KDS G+K + + P
Sbjct: 1437 RDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSA--------SGQKNKPREERDLP 1488
Query: 713 TLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTK 772
K T D + S S +R+ K + T +++P+ E+TK
Sbjct: 1489 K-KGTGDSKKSNSSPSRDRKPHDHKATYDTKRPN----------------------EETK 1525
Query: 773 RV-----SSRKKPALKATSDEKDS---VLYIAREKKDGEKSRTVSSQKQPALKAICDKED 824
V R+K L+A ++++ S +LYI + + ++ Q DK
Sbjct: 1526 SVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQ--------IDKST 1577
Query: 825 SVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQ 884
P S + A + ++ DS SN+ +K+ + SG +S K
Sbjct: 1578 VKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNV--SVKEEESSGNIS--KDLKD 1633
Query: 885 KVIFKKKVSL 894
K++ K K SL
Sbjct: 1634 KIVEKAKESL 1643
Score = 43.1 bits (100), Expect = 0.001
Identities = 59/271 (21%), Positives = 107/271 (39%), Gaps = 37/271 (13%)
Query: 635 SRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIA 694
SR + S P L KD KS+ SE PG D K +
Sbjct: 857 SRNIGSNYPEKLSARD---------GHNQKDNTKSKEKESENAPG-----DGKGNKHKKH 902
Query: 695 RGKKDGEKTRTV-------SSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSG 747
R ++ GE++ +S+K + + L + D R + S
Sbjct: 903 RKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESI 962
Query: 748 LKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAR---EKKDGEK 804
+ +EKD + K G+KTKR + + +K++++ A+ EK DGE+
Sbjct: 963 TFKSVSEKDK-RERDKPKAKGDKTKRKNDG------SAVSKKENIVKPAKGPQEKVDGER 1015
Query: 805 SRTVSSQKQPALKAICD---KEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKD-SV 860
R S + +P +K + K D+ + ++ +KDE+I+GT + K + K
Sbjct: 1016 ER--SPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1073
Query: 861 SNIPTEIKDGQQSGTVSPQKQSAQKVIFKKK 891
+ + +S ++ +++ A+K K K
Sbjct: 1074 EKVKKDYSKDVKSEKLTTKEEKAKKPNEKNK 1104
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 75.1 bits (183), Expect = 3e-13
Identities = 161/790 (20%), Positives = 292/790 (36%), Gaps = 107/790 (13%)
Query: 125 FAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEG 184
F P D + E + T + + E DKT+ N + KE
Sbjct: 975 FVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVS-KKEN 1033
Query: 185 KALPATG--QKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTL 242
PA G +K + E+ P +K + + T S SS++ T T
Sbjct: 1034 IVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPK-----TDNTKSSSSSQKDEKITGTP 1088
Query: 243 KEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEG--PISGTVSS 300
++A SK+A +++ P + +K ++ S+ + A + E P+
Sbjct: 1089 RKAH--SKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK 1146
Query: 301 QKQPAEKATSDEKDSVSNI------ATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIA 354
+K+ E+ D+ S++ TEI K + P + + K K+SL A
Sbjct: 1147 RKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPA 1206
Query: 355 TRIMGGGKSGTV--SSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
+I ++G S++ +K S+K +S ++++K G V + T
Sbjct: 1207 KKIKLNRETGKKIGSTENISNTKEPSEKLEST---SSKVKQEKVKGKVR-------RKVT 1256
Query: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK 472
E S S + + + T S+ P K+ ++ D+ + +++ T ++
Sbjct: 1257 GTEGSSSTLV------DYTSTSSTGGSPVRKSE-EKTDTKRTVIKTMEEYNNDNTAPAED 1309
Query: 473 PPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI 532
+ + E +D + ++ +SS KPAS + + + +K+ E
Sbjct: 1310 VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP 1369
Query: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA 592
S K+ K T D + I E K + S SSEK + D SVL
Sbjct: 1370 SEKIQ-------KFTKDVSHEI--IQHEVKSSKNS--ASSEK----GKTKDRDYSVLE-- 1412
Query: 593 RGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDE 652
K+ EK K + +K S +E+ +F ++++ K+ S K S + + K +
Sbjct: 1413 --KENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPN 1470
Query: 653 EDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPP 712
D K R +E + S KDS G+K + + P
Sbjct: 1471 RDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSA--------SGQKNKPREERDLP 1522
Query: 713 TLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTK 772
K T D + S S +R+ K + T +++P+ E+TK
Sbjct: 1523 K-KGTGDSKKSNSSPSRDRKPHDHKATYDTKRPN----------------------EETK 1559
Query: 773 RV-----SSRKKPALKATSDEKDS---VLYIAREKKDGEKSRTVSSQKQPALKAICDKED 824
V R+K L+A ++++ S +LYI + + ++ Q DK
Sbjct: 1560 SVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQ--------IDKST 1611
Query: 825 SVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQ 884
P S + A + ++ DS SN+ +K+ + SG +S K
Sbjct: 1612 VKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNV--SVKEEESSGNIS--KDLKD 1667
Query: 885 KVIFKKKVSL 894
K++ K K SL
Sbjct: 1668 KIVEKAKESL 1677
Score = 43.1 bits (100), Expect = 0.001
Identities = 59/271 (21%), Positives = 107/271 (39%), Gaps = 37/271 (13%)
Query: 635 SRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIA 694
SR + S P L KD KS+ SE PG D K +
Sbjct: 891 SRNIGSNYPEKLSARD---------GHNQKDNTKSKEKESENAPG-----DGKGNKHKKH 936
Query: 695 RGKKDGEKTRTV-------SSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSG 747
R ++ GE++ +S+K + + L + D R + S
Sbjct: 937 RKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESI 996
Query: 748 LKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAR---EKKDGEK 804
+ +EKD + K G+KTKR + + +K++++ A+ EK DGE+
Sbjct: 997 TFKSVSEKDK-RERDKPKAKGDKTKRKNDG------SAVSKKENIVKPAKGPQEKVDGER 1049
Query: 805 SRTVSSQKQPALKAICD---KEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKD-SV 860
R S + +P +K + K D+ + ++ +KDE+I+GT + K + K
Sbjct: 1050 ER--SPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1107
Query: 861 SNIPTEIKDGQQSGTVSPQKQSAQKVIFKKK 891
+ + +S ++ +++ A+K K K
Sbjct: 1108 EKVKKDYSKDVKSEKLTTKEEKAKKPNEKNK 1138
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 73.6 bits (179), Expect = 8e-13
Identities = 172/754 (22%), Positives = 277/754 (36%), Gaps = 98/754 (12%)
Query: 156 SAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHIS 215
+AE+ CG M + + K + G A E PL T + +
Sbjct: 184 TAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLV 243
Query: 216 TRFLGGMDSLT-----SSEESSERPPLSTLTLKEADPSSKAAMRRKDS---------PPP 261
+ L ++E E+ P +L E + + S P
Sbjct: 244 EKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPR 303
Query: 262 GKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIAT 321
S K+ +EK T K IA E KE +S K+ +EK T K IA
Sbjct: 304 EITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAW 363
Query: 322 EIKKGQ-QSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPA-SKATSD 379
E K+ ++G V+ + KV+ K + ++ T+ + + Q+ P+ SK D
Sbjct: 364 EKKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTK--ESSTKASANDQRFPSESKQEED 421
Query: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
+ S D S++ Q + + ++ V I E+++ K K
Sbjct: 422 EEYSC--------DSRSLFESSAKIQVCIPESIYQK--VMEINREVEEPPK-------KP 464
Query: 440 PALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEK- 498
A K + ++SV N A E+K+ E++ PP EE S D E
Sbjct: 465 SAFKPAIEMQNSVPNKAFELKN-EQTLRADPMFPPESKQKDYEENS--------WDSESL 515
Query: 499 SRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 558
TVS + KAT ++ K +G++ S K LK T + S+ A
Sbjct: 516 CETVSQKDVCLPKATHQKEID-------KINGKLEE--SPNKDGLLKATCGMKVSIPTKA 566
Query: 559 RENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 618
E KD + + KP + +++ + SV N A K E+T R L + S +
Sbjct: 567 LELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELK-NEQTLRADE----ILPSESKQ 621
Query: 619 KDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 678
KD N S +L T ++D L A K+ +K
Sbjct: 622 KDYEEN---------------SWDTESLCETVSQKDVCLPKAAHQKEIDKIN-------- 658
Query: 679 GLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSR 738
G S KD +L G K T+ + T KA E+ S A E + ++
Sbjct: 659 GKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNK 718
Query: 739 TVSSEKPSGLKATSAEKDSVL-NIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAR 797
+ + L+A D +L + ++ K Y E SS +L T +KD L A
Sbjct: 719 ALELKNEQTLRA-----DEILPSESKQKDYEE-----SSWDSESLCETVSQKDVCLPKAT 768
Query: 798 EKKDGEK---SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATS 854
+K+ +K S LKA C + S+P A E D Q +K A +
Sbjct: 769 HQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI 828
Query: 855 DKKDSVSNIPTEIKDGQ--QSGTVSPQKQSAQKV 886
+ + SV N E+K+ Q ++ + P + +KV
Sbjct: 829 EMQKSVPNKALELKNEQTLRADQMFPSESKQKKV 862
Score = 56.6 bits (135), Expect = 1e-07
Identities = 123/561 (21%), Positives = 215/561 (38%), Gaps = 77/561 (13%)
Query: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
G S + P ++ T D +S + + + P ++ T D +S+
Sbjct: 219 GTSAGTPDEAAPLAERTPDTAESLVEKTPD------------EAAPLVERTPDTAESLVE 266
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDE-KDSVSNIATEIKDGEKSGTVSSQKPPALTAT 479
+ GT S + Q KAT+ + + S EI K +S+K T
Sbjct: 267 KTPDEAASLVEGT-SDKIQCLEKATSGKFEQSAEETPREITSPAKE---TSEK-----FT 317
Query: 480 SDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKD-----GEISR 534
+G IA E K+ +S K+ + K T K I KK+ G ++R
Sbjct: 318 WPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVAR 377
Query: 535 KVSSQKPPTLKGTSD------EEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSV 588
S++ KG S +E S A + + +S+ E+ S E +
Sbjct: 378 VTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSAK 437
Query: 589 LNIARGKKYGEKTKRVSSR-----KKPS-LEATSDEKDSFSNITREKKDGEISRKVSSQK 642
+ + + +K ++ KKPS + + ++S N E K+ E + +
Sbjct: 438 IQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNSVPNKAFELKN-EQTLRADPMF 496
Query: 643 PPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEK 702
PP K EE+S D E S+K L + +K+ ++ GK +
Sbjct: 497 PPESKQKDYEENSW--------DSESLCETVSQKDVCLPKATHQKE--IDKINGKLEE-- 544
Query: 703 TRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIA 762
S K LKAT + S+ + A E KD + + KPS + + + SV N
Sbjct: 545 ----SPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPN-- 598
Query: 763 RGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDK 822
K + + + L+A D +L ++KD E++ S + + + K
Sbjct: 599 ---------KALELKNEQTLRA-----DEILPSESKQKDYEEN---SWDTESLCETVSQK 641
Query: 823 EDSVPNMATEKKDEQISGTV--SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQK 880
+ +P A +K+ ++I+G + S K LKA K S+ E+ D Q P+K
Sbjct: 642 DVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEK 701
Query: 881 QSAQKVIFKKKVSLLNIATRI 901
SA + + + S+ N A +
Sbjct: 702 PSAFEPAIEMQKSVPNKALEL 722
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 67.8 bits (164), Expect = 5e-11
Identities = 163/775 (21%), Positives = 292/775 (37%), Gaps = 138/775 (17%)
Query: 223 DSLTSSEESSE--RPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKD 280
D+ +SS+E+ +P + +K + S+K + RK +P PGK
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGK----------------- 244
Query: 281 SVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAR 340
V ++ ++K G + K+P E++ S E+ S E ++ +GT S Q +++
Sbjct: 245 -VGDVTPQVKGGALP-PAKRAKKPEEESESSEEGS------ESEEEAPAGTRS-QVKASE 295
Query: 341 KVIFKKKVSLLNIATRIMGG-----GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGL 395
K++ + S T G GK+G V+SQ + A K D S + E D
Sbjct: 296 KILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK-AGKPEEDSESS----SEESSD-- 348
Query: 396 QCGTVSSQKQPALKA-----TTDEEDSVSNIATEIKDGEKSGTVSS---QKQPAL-KATT 446
S ++ PA KA + + V + K+ + G + + PA+ KA
Sbjct: 349 -----SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQA 403
Query: 447 DEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRK 506
+++ S ++E D E ++ PA S + V + + K+ + +
Sbjct: 404 GKREEDSQSSSEESDSE-------EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
Query: 507 KPASKATS------DEKDSFSNITRGKKDGE-ISRKVSSQKPPTLKGTSDEEDSVLGIAR 559
+ A + E+DS S+ D E ++ ++Q P K + S +G+
Sbjct: 457 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516
Query: 560 ENKD-GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 618
K G P + E+DS + E++ S + P+ A + E
Sbjct: 517 LGKGAGPVPPGKVGPATPSAQVGKWEEDS-------ESSSEESSDSSDGEVPTAVAPAQE 569
Query: 619 KDSFSNITREK-----------KDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGE 667
K S NI + K K G ++ +V ++KP D +S E
Sbjct: 570 K-SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKP------MDNSES---------SEE 613
Query: 668 KSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLK-----------A 716
S + SE+ P + K + L I + K +KT T +S K ++ A
Sbjct: 614 SSDSADSEEAPAAMTAAQAKPA-LKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 717 TSDEEDSVLSIARENKDGEKS----RTVSSEKPSGLKATSAEKDSV--------LNIARG 764
TS S + E S + S E+ +GL T + SV ++
Sbjct: 673 TSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVK 732
Query: 765 KKYGEKTKRVSSRKK-PALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKE 823
G+ T V K P + EK + E+ D E++ +Q + ++K K
Sbjct: 733 GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKA 792
Query: 824 DSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSA 883
+ A K GT+S+ + A K+ S S + +++ Q S ++ S
Sbjct: 793 NPAAARAPSAK-----GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
Query: 884 QKVIFKKKVSLLNIATRITGGWK-SGTVIRQAIEHDECLCYTGIKPSDVLYESHA 937
V ++ A TG + SG+ ++ +E +KPS ++ A
Sbjct: 848 PSV----GKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRA 898
Score = 55.8 bits (133), Expect = 2e-07
Identities = 156/742 (21%), Positives = 267/742 (35%), Gaps = 137/742 (18%)
Query: 226 TSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPP-----PGKV-SSQKQPAEKATSDDK 279
+ SEE++ P ++K+ + A R S PGKV ++ Q +++ S K
Sbjct: 769 SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Query: 280 DSVSNI--ATEIKEGP---------ISGTVSSQKQPAEKATSDEKDSVSNIATEI----- 323
V N +T + GP ++ +Q P E + S E++S S E
Sbjct: 829 PPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVK 888
Query: 324 ---KKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQ--KQPASKATS 378
K Q ++P K+S RK GK+G ++Q KQ S ++S
Sbjct: 889 PSGKTHQIRAALAPAKESPRK------------GAAPTPPGKTGPSAAQAGKQDDSGSSS 936
Query: 379 DKTDS------ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSG 432
+++DS A+ A IK L V + PA A T + ++ + + E +
Sbjct: 937 EESDSDGEAPAAVTSAQVIKPPLIF--VDPNRSPAGPAATPAQAQAASTPRKARASESTA 994
Query: 433 TVSSQKQ------PALKATTD----------------------EKDSVSNIATEIKDGEK 464
SS + PA + T S S ++ I DG+K
Sbjct: 995 RSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKK 1054
Query: 465 SGTVSSQKPPA---LTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFS 521
++Q A L ATS + SV + K V K A +++ D +DS
Sbjct: 1055 QEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATK-APESSDDSEDSSD 1113
Query: 522 NITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGE----KSRTVSSEKPPG 577
+ + ++DGE + S S E V A E+ + + +S PG
Sbjct: 1114 SSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPG 1173
Query: 578 LKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRK 637
L ++ + K SS S A D+ D ++ G +S K
Sbjct: 1174 LTPANSQASKAT-----------PKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 1222
Query: 638 VSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGK 697
++ A GT+ ++ S KP K + + S L +
Sbjct: 1223 TGGKE--AASGTTPQK--------------------SRKPK--KGAGNPQASTLAL---- 1254
Query: 698 KDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDS 757
T+ + Q P +A + SV+ + E + E+ + V + K S K + K
Sbjct: 1255 -QSNITQCLLGQPWPLNEA--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRK 1311
Query: 758 VLNIARGKKYGEKTKRVSSRKKPAL-----KATSDEKDSVLYIAREKKDGEKSRTVSSQK 812
+ G + +T R +KK + S EK S + K+D +
Sbjct: 1312 L----SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKG 1367
Query: 813 QPALKAICDKEDSVPNMATEKKDEQISG-TVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 871
+ +L + K++ P +K + G S+ K K SDK+ + K +
Sbjct: 1368 KGSLGSQGAKDE--PEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAK 1425
Query: 872 QSGTVSPQKQSAQKVIFKKKVS 893
++ T + S +K KKK +
Sbjct: 1426 KASTKDSESPSQKKKKKKKKTA 1447
Score = 54.7 bits (130), Expect = 4e-07
Identities = 143/669 (21%), Positives = 239/669 (35%), Gaps = 102/669 (15%)
Query: 179 NVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSE----- 233
+V GKA+ AT +A PE+ G + + SEE +E
Sbjct: 846 SVPSVGKAV-ATAAQAQTGPEEDS-----------------GSSEEESDSEEEAETLAQV 887
Query: 234 RPPLSTLTLKEADPSSKAAMRRKDSP-PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEG 292
+P T ++ A +K + R+ +P PPGK A K DD S S + E
Sbjct: 888 KPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK--QDDSGSSSEESDSDGEA 945
Query: 293 PISGT-----------VSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARK 341
P + T V + PA A + + ++ + + + + S +
Sbjct: 946 PAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDED 1005
Query: 342 VIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVS 401
VI + I T ++ + + K + A+S K S I DG + +
Sbjct: 1006 VIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS------RISDGKKQEGPA 1059
Query: 402 SQKQPA---LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATE 458
+Q A L AT+ + SV T K V Q A +++ D +DS + +
Sbjct: 1060 TQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ-QATKAPESSDDSEDSSDSSSGS 1118
Query: 459 IKDGE------KSGTVSSQKPPAL------TATSDEEGSVLSIARENKDGEKSRTVSSRK 506
+DGE + T+ P TA E V++ ++ G + ++
Sbjct: 1119 EEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPAN 1178
Query: 507 KPASKATS--DEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDG 564
ASKAT D S S+ K D + ++ Q+ +L K+
Sbjct: 1179 SQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAA----------GMLSPKTGGKEA 1228
Query: 565 EKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSN 624
T + P K + + + S L + T+ + + P EA + S
Sbjct: 1229 ASGTTPQKSRKPK-KGAGNPQASTLALQ-----SNITQCLLGQPWPLNEA--QVQASVVK 1280
Query: 625 ITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATS 684
+ E + E + V + K + KG + + G D +RT S+K L A
Sbjct: 1281 VLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAARTPRSKKKKKLGAGE 1334
Query: 685 DEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSD--EEDSVLSIARENKDGEKSRTVSS 742
+ SV EKT T S K KA+ D E+ S+ + E
Sbjct: 1335 GGEASV--------SPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEE---- 1382
Query: 743 EKPSGLKATSAEKDSVLNIARGKKYGEKTKR---VSSRKKPALKATSDEKDSVLYIAREK 799
E G+ S + KK +K K+ +KK A KA++ + +S ++K
Sbjct: 1383 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKK 1442
Query: 800 KDGEKSRTV 808
K +TV
Sbjct: 1443 KKKTAEQTV 1451
Score = 47.8 bits (112), Expect = 5e-05
Identities = 126/637 (19%), Positives = 238/637 (37%), Gaps = 96/637 (15%)
Query: 335 QKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS-KATSDKTDSALNIATEIKD 393
++QS +K + V+LL+I T + G ++ A+ +A + ++ + ++
Sbjct: 31 KEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEE 90
Query: 394 GLQCGTVSSQKQPALKATTDE---EDSVSNIATEIK-DGEKSG-TVSSQKQPALKATTDE 448
+ +++ P L +T D S++ + K + EK+G T +S PA T
Sbjct: 91 EEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT--- 147
Query: 449 KDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDG------------ 496
V+N+ + K KS S+ L + ++EEGSV + K G
Sbjct: 148 ---VANLLSG-KSPRKSAEPSANT--TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 497 ---------------------EKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI--- 532
K+ +VS+++ PA KA + ++T K G +
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKA-APAPGKVGDVTPQVKGGALPPA 260
Query: 533 --SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEK-----SRTVSSEKPPGLKASSDEK 585
++K + + +G+ EE++ G + K EK + + ++ PG A+
Sbjct: 261 KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPP 320
Query: 586 DSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEIS---------- 635
+A K G+ + S + S + + +E + + + K G+ S
Sbjct: 321 GKAGAVASQTKAGKPEEDSESSSEESSD-SEEETPAAKALLQAKASGKTSQVGAASAPAK 379
Query: 636 ---RKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLN 692
RK ++ PP G + + + G E+ + S E+ P S + V
Sbjct: 380 ESPRKGAAPAPPGKTGPAVAK-AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 693 IARGKKDGEKTRTVSSQKPP--------TLKATSDEEDSVLSIARENKDGE--KSRTVSS 742
+ K E R ++ PP ++ EEDS S + D E + +
Sbjct: 439 ASAPAK--ESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496
Query: 743 EKPSGLKATSAEKDSVLNIA-RGKKYGEKTKRVSSRKKPALKATSDEKDSVLYI--AREK 799
KP G K+ + S + + GK G P+ + E+DS + +
Sbjct: 497 VKPLG-KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 800 KDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQ---KQPALKATSDK 856
DGE V+ ++ +L I + P + K Q +G V+ Q ++P + S +
Sbjct: 556 SDGEVPTAVAPAQEKSLGNILQAK---PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 612
Query: 857 KDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVS 893
+ S S E + P + Q KK +
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 67.8 bits (164), Expect = 5e-11
Identities = 163/775 (21%), Positives = 292/775 (37%), Gaps = 138/775 (17%)
Query: 223 DSLTSSEESSE--RPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKD 280
D+ +SS+E+ +P + +K + S+K + RK +P PGK
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGK----------------- 244
Query: 281 SVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAR 340
V ++ ++K G + K+P E++ S E+ S E ++ +GT S Q +++
Sbjct: 245 -VGDVTPQVKGGALP-PAKRAKKPEEESESSEEGS------ESEEEAPAGTRS-QVKASE 295
Query: 341 KVIFKKKVSLLNIATRIMGG-----GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGL 395
K++ + S T G GK+G V+SQ + A K D S + E D
Sbjct: 296 KILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK-AGKPEEDSESS----SEESSD-- 348
Query: 396 QCGTVSSQKQPALKA-----TTDEEDSVSNIATEIKDGEKSGTVSS---QKQPAL-KATT 446
S ++ PA KA + + V + K+ + G + + PA+ KA
Sbjct: 349 -----SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQA 403
Query: 447 DEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRK 506
+++ S ++E D E ++ PA S + V + + K+ + +
Sbjct: 404 GKREEDSQSSSEESDSE-------EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
Query: 507 KPASKATS------DEKDSFSNITRGKKDGE-ISRKVSSQKPPTLKGTSDEEDSVLGIAR 559
+ A + E+DS S+ D E ++ ++Q P K + S +G+
Sbjct: 457 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516
Query: 560 ENKD-GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 618
K G P + E+DS + E++ S + P+ A + E
Sbjct: 517 LGKGAGPVPPGKVGPATPSAQVGKWEEDS-------ESSSEESSDSSDGEVPTAVAPAQE 569
Query: 619 KDSFSNITREK-----------KDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGE 667
K S NI + K K G ++ +V ++KP D +S E
Sbjct: 570 K-SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKP------MDNSES---------SEE 613
Query: 668 KSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLK-----------A 716
S + SE+ P + K + L I + K +KT T +S K ++ A
Sbjct: 614 SSDSADSEEAPAAMTAAQAKPA-LKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 717 TSDEEDSVLSIARENKDGEKS----RTVSSEKPSGLKATSAEKDSV--------LNIARG 764
TS S + E S + S E+ +GL T + SV ++
Sbjct: 673 TSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVK 732
Query: 765 KKYGEKTKRVSSRKK-PALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKE 823
G+ T V K P + EK + E+ D E++ +Q + ++K K
Sbjct: 733 GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKA 792
Query: 824 DSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSA 883
+ A K GT+S+ + A K+ S S + +++ Q S ++ S
Sbjct: 793 NPAAARAPSAK-----GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
Query: 884 QKVIFKKKVSLLNIATRITGGWK-SGTVIRQAIEHDECLCYTGIKPSDVLYESHA 937
V ++ A TG + SG+ ++ +E +KPS ++ A
Sbjct: 848 PSV----GKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRA 898
Score = 54.7 bits (130), Expect = 4e-07
Identities = 150/743 (20%), Positives = 264/743 (35%), Gaps = 102/743 (13%)
Query: 226 TSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPP-----PGKV-SSQKQPAEKATSDDK 279
+ SEE++ P ++K+ + A R S PGKV ++ Q +++ S K
Sbjct: 769 SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Query: 280 DSVSNI--ATEIKEGP---------ISGTVSSQKQPAEKATSDEKDSVSNIATEI----- 323
V N +T + GP ++ +Q P E + S E++S S E
Sbjct: 829 PPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVK 888
Query: 324 ---KKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQ--KQPASKATS 378
K Q ++P K+S RK GK+G ++Q KQ S ++S
Sbjct: 889 PSGKTHQIRAALAPAKESPRK------------GAAPTPPGKTGPSAAQAGKQDDSGSSS 936
Query: 379 DKTDS------ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSG 432
+++DS A+ A IK L V + PA A T + ++ + + E +
Sbjct: 937 EESDSDGEAPAAVTSAQVIKPPLIF--VDPNRSPAGPAATPAQAQAASTPRKARASESTA 994
Query: 433 TVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARE 492
SS + + I T + + + K A+S +E S +S +
Sbjct: 995 RSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS---D 1051
Query: 493 NKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPP--------TL 544
K E T S+K PAS + +K E V+ +P TL
Sbjct: 1052 GKKQEGPATQVSKKNPASLPLTQAALK----VLAQKASEAQPPVARTQPSSGVDSAVGTL 1107
Query: 545 KGTSDEEDSVL--GIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA------RGKK 596
TS + SV G + K +++ P S D DS +G K
Sbjct: 1108 PATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAK 1167
Query: 597 YGEKTKRVSSRKKPSLEATSDE--KDSFSNITREKKDGEISRKVSSQKPPALKGTS--DE 652
SR + +E T+ E +D ++ G ++ ++ A K T D
Sbjct: 1168 SAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDS 1227
Query: 653 EDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPP 712
SV D + + ++ G+ + + +K + + + +
Sbjct: 1228 SPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQAS 1287
Query: 713 TLKATSD----------------EEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKD 756
TL S+ + SV+ + E + E+ + V + K S K + K
Sbjct: 1288 TLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKR 1347
Query: 757 SVLNIARGKKYGEKTKRVSSRKKPAL-----KATSDEKDSVLYIAREKKDGEKSRTVSSQ 811
+ G + +T R +KK + S EK S + K+D +
Sbjct: 1348 KL----SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKK 1403
Query: 812 KQPALKAICDKEDSVPNMATEKKDEQISG-TVSSQKQPALKATSDKKDSVSNIPTEIKDG 870
+ +L + K++ P +K + G S+ K K SDK+ + K
Sbjct: 1404 GKGSLGSQGAKDE--PEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKA 1461
Query: 871 QQSGTVSPQKQSAQKVIFKKKVS 893
+++ T + S +K KKK +
Sbjct: 1462 KKASTKDSESPSQKKKKKKKKTA 1484
Score = 50.1 bits (118), Expect = 1e-05
Identities = 147/700 (21%), Positives = 241/700 (34%), Gaps = 127/700 (18%)
Query: 179 NVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSE----- 233
+V GKA+ AT +A PE+ G + + SEE +E
Sbjct: 846 SVPSVGKAV-ATAAQAQTGPEEDS-----------------GSSEEESDSEEEAETLAQV 887
Query: 234 RPPLSTLTLKEADPSSKAAMRRKDSP-PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEG 292
+P T ++ A +K + R+ +P PPGK A K DD S S + E
Sbjct: 888 KPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK--QDDSGSSSEESDSDGEA 945
Query: 293 PISGT-----------VSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARK 341
P + T V + PA A + + ++ + + + + S +
Sbjct: 946 PAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDED 1005
Query: 342 VIFKKKVSLLNIATRI---------------MGGGKSGTVSS-------QKQPASKATSD 379
VI + I T + M G S SS Q+ PA++ +
Sbjct: 1006 VIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKK 1065
Query: 380 K------TDSALNIATEIKDGLQCGTVSSQKQPA-------LKATTDEEDSVSNIATEIK 426
T +AL + + Q +Q L AT+ + SV T
Sbjct: 1066 NPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKL 1125
Query: 427 DGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGE-----KSGTVSSQKPPAL----- 476
K V Q A +++ D +DS + + +DGE KS P
Sbjct: 1126 RKPKLPEVQ-QATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVE 1184
Query: 477 -TATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATS--DEKDSFSNITRGKKDGEIS 533
TA E V++ ++ G + ++ ASKAT D S S+ K D +
Sbjct: 1185 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1244
Query: 534 RKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIAR 593
++ Q+ +L K+ T + P K + + + S L +
Sbjct: 1245 QEAKPQQAA----------GMLSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLALQ- 1292
Query: 594 GKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEE 653
T+ + + P EA + S + E + E + V + K + KG +
Sbjct: 1293 ----SNITQCLLGQPWPLNEA--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRK 1346
Query: 654 DSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPT 713
+ G D +RT S+K L A + SV EKT T S K
Sbjct: 1347 RKLSG------DQPAARTPRSKKKKKLGAGEGGEASV--------SPEKTSTTSKGKAKR 1392
Query: 714 LKATSD--EEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKT 771
KA+ D E+ S+ + E E G+ S + KK +K
Sbjct: 1393 DKASGDVKEKKGKGSLGSQGAKDEPEE----ELQKGMGTVEGGDQSNPKSKKEKKKSDKR 1448
Query: 772 KR---VSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTV 808
K+ +KK A KA++ + +S ++KK +TV
Sbjct: 1449 KKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1488
Score = 47.8 bits (112), Expect = 5e-05
Identities = 126/637 (19%), Positives = 238/637 (37%), Gaps = 96/637 (15%)
Query: 335 QKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS-KATSDKTDSALNIATEIKD 393
++QS +K + V+LL+I T + G ++ A+ +A + ++ + ++
Sbjct: 31 KEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEE 90
Query: 394 GLQCGTVSSQKQPALKATTDE---EDSVSNIATEIK-DGEKSG-TVSSQKQPALKATTDE 448
+ +++ P L +T D S++ + K + EK+G T +S PA T
Sbjct: 91 EEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT--- 147
Query: 449 KDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDG------------ 496
V+N+ + K KS S+ L + ++EEGSV + K G
Sbjct: 148 ---VANLLSG-KSPRKSAEPSANT--TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 497 ---------------------EKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI--- 532
K+ +VS+++ PA KA + ++T K G +
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKA-APAPGKVGDVTPQVKGGALPPA 260
Query: 533 --SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEK-----SRTVSSEKPPGLKASSDEK 585
++K + + +G+ EE++ G + K EK + + ++ PG A+
Sbjct: 261 KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPP 320
Query: 586 DSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEIS---------- 635
+A K G+ + S + S + + +E + + + K G+ S
Sbjct: 321 GKAGAVASQTKAGKPEEDSESSSEESSD-SEEETPAAKALLQAKASGKTSQVGAASAPAK 379
Query: 636 ---RKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLN 692
RK ++ PP G + + + G E+ + S E+ P S + V
Sbjct: 380 ESPRKGAAPAPPGKTGPAVAK-AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 693 IARGKKDGEKTRTVSSQKPP--------TLKATSDEEDSVLSIARENKDGE--KSRTVSS 742
+ K E R ++ PP ++ EEDS S + D E + +
Sbjct: 439 ASAPAK--ESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496
Query: 743 EKPSGLKATSAEKDSVLNIA-RGKKYGEKTKRVSSRKKPALKATSDEKDSVLYI--AREK 799
KP G K+ + S + + GK G P+ + E+DS + +
Sbjct: 497 VKPLG-KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 800 KDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQ---KQPALKATSDK 856
DGE V+ ++ +L I + P + K Q +G V+ Q ++P + S +
Sbjct: 556 SDGEVPTAVAPAQEKSLGNILQAK---PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 612
Query: 857 KDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVS 893
+ S S E + P + Q KK +
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 67.8 bits (164), Expect = 5e-11
Identities = 163/775 (21%), Positives = 292/775 (37%), Gaps = 138/775 (17%)
Query: 223 DSLTSSEESSE--RPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKD 280
D+ +SS+E+ +P + +K + S+K + RK +P PGK
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGK----------------- 244
Query: 281 SVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAR 340
V ++ ++K G + K+P E++ S E+ S E ++ +GT S Q +++
Sbjct: 245 -VGDVTPQVKGGALP-PAKRAKKPEEESESSEEGS------ESEEEAPAGTRS-QVKASE 295
Query: 341 KVIFKKKVSLLNIATRIMGG-----GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGL 395
K++ + S T G GK+G V+SQ + A K D S + E D
Sbjct: 296 KILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK-AGKPEEDSESS----SEESSD-- 348
Query: 396 QCGTVSSQKQPALKA-----TTDEEDSVSNIATEIKDGEKSGTVSS---QKQPAL-KATT 446
S ++ PA KA + + V + K+ + G + + PA+ KA
Sbjct: 349 -----SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQA 403
Query: 447 DEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRK 506
+++ S ++E D E ++ PA S + V + + K+ + +
Sbjct: 404 GKREEDSQSSSEESDSE-------EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
Query: 507 KPASKATS------DEKDSFSNITRGKKDGE-ISRKVSSQKPPTLKGTSDEEDSVLGIAR 559
+ A + E+DS S+ D E ++ ++Q P K + S +G+
Sbjct: 457 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516
Query: 560 ENKD-GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 618
K G P + E+DS + E++ S + P+ A + E
Sbjct: 517 LGKGAGPVPPGKVGPATPSAQVGKWEEDS-------ESSSEESSDSSDGEVPTAVAPAQE 569
Query: 619 KDSFSNITREK-----------KDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGE 667
K S NI + K K G ++ +V ++KP D +S E
Sbjct: 570 K-SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKP------MDNSES---------SEE 613
Query: 668 KSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLK-----------A 716
S + SE+ P + K + L I + K +KT T +S K ++ A
Sbjct: 614 SSDSADSEEAPAAMTAAQAKPA-LKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 717 TSDEEDSVLSIARENKDGEKS----RTVSSEKPSGLKATSAEKDSV--------LNIARG 764
TS S + E S + S E+ +GL T + SV ++
Sbjct: 673 TSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVK 732
Query: 765 KKYGEKTKRVSSRKK-PALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKE 823
G+ T V K P + EK + E+ D E++ +Q + ++K K
Sbjct: 733 GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKA 792
Query: 824 DSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSA 883
+ A K GT+S+ + A K+ S S + +++ Q S ++ S
Sbjct: 793 NPAAARAPSAK-----GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
Query: 884 QKVIFKKKVSLLNIATRITGGWK-SGTVIRQAIEHDECLCYTGIKPSDVLYESHA 937
V ++ A TG + SG+ ++ +E +KPS ++ A
Sbjct: 848 PSV----GKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRA 898
Score = 56.6 bits (135), Expect = 1e-07
Identities = 150/724 (20%), Positives = 266/724 (36%), Gaps = 102/724 (14%)
Query: 226 TSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPP-----PGKV-SSQKQPAEKATSDDK 279
+ SEE++ P ++K+ + A R S PGKV ++ Q +++ S K
Sbjct: 769 SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Query: 280 DSVSNI--ATEIKEGP---------ISGTVSSQKQPAEKATSDEKDSVSNIATEI----- 323
V N +T + GP ++ +Q P E + S E++S S E
Sbjct: 829 PPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVK 888
Query: 324 ---KKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQ--KQPASKATS 378
K Q ++P K+S RK GK+G ++Q KQ S ++S
Sbjct: 889 PSGKTHQIRAALAPAKESPRK------------GAAPTPPGKTGPSAAQAGKQDDSGSSS 936
Query: 379 DKTDS------ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSG 432
+++DS A+ A IK L V + PA A T + ++ + + E +
Sbjct: 937 EESDSDGEAPAAVTSAQVIKPPLIF--VDPNRSPAGPAATPAQAQAASTPRKARASESTA 994
Query: 433 TVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARE 492
SS + + I T + + + K A+S +E S +S
Sbjct: 995 RSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS---- 1050
Query: 493 NKDGEKSRTVSSRKKPAS---KATSDEKDSF----SNITRGKKDGEISRKVSSQKPPTLK 545
DG+K +++ A ATS + S +N R K E+ + +++ P +
Sbjct: 1051 --DGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ--ATKAPESSD 1106
Query: 546 GTSDEEDSVLGIAR--ENKDGEKSRTVSSEKPPGLK------ASSDEKDSVLNIARGKKY 597
+ D DS G E G KS P + A+ +D V+ ++
Sbjct: 1107 DSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLS 1166
Query: 598 GEKTKRVSSRKKPSLEATS--DEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDS 655
G T ++ + +AT D S S+ K D + ++ Q+ +
Sbjct: 1167 GYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGM--------- 1217
Query: 656 VLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLK 715
L K+ T + P K + + S L + T+ + Q P +
Sbjct: 1218 -LSPKTGGKEAASGTTPQKSRKPK-KGAGNPQASTLAL-----QSNITQCLLGQPWPLNE 1270
Query: 716 ATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVS 775
A + SV+ + E + E+ + V + K S K + K + G + +T R
Sbjct: 1271 A--QVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKL----SGDQPAARTPRSK 1324
Query: 776 SRKKPAL-----KATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMA 830
+KK + S EK S + K+D + + +L + K++ P
Sbjct: 1325 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDE--PEEE 1382
Query: 831 TEKKDEQISG-TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFK 889
+K + G S+ K K SDK+ + K +++ T + S +K K
Sbjct: 1383 LQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKK 1442
Query: 890 KKVS 893
KK +
Sbjct: 1443 KKTA 1446
Score = 55.8 bits (133), Expect = 2e-07
Identities = 144/668 (21%), Positives = 238/668 (35%), Gaps = 101/668 (15%)
Query: 179 NVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSE----- 233
+V GKA+ AT +A PE+ G + + SEE +E
Sbjct: 846 SVPSVGKAV-ATAAQAQTGPEEDS-----------------GSSEEESDSEEEAETLAQV 887
Query: 234 RPPLSTLTLKEADPSSKAAMRRKDSP-PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEG 292
+P T ++ A +K + R+ +P PPGK A K DD S S + E
Sbjct: 888 KPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGK--QDDSGSSSEESDSDGEA 945
Query: 293 PISGT-----------VSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARK 341
P + T V + PA A + + ++ + + + + S +
Sbjct: 946 PAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDED 1005
Query: 342 VIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVS 401
VI + I T ++ + + K + A+S K S I DG + +
Sbjct: 1006 VIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESS------RISDGKKQEGPA 1059
Query: 402 SQKQPA---LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATE 458
+Q A L AT+ + SV T K V Q A +++ D +DS + +
Sbjct: 1060 TQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ-QATKAPESSDDSEDSSDSSSGS 1118
Query: 459 IKDGE-----KSGTVSSQKPPAL------TATSDEEGSVLSIARENKDGEKSRTVSSRKK 507
+DGE KS P TA E V++ ++ G + ++
Sbjct: 1119 EEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1178
Query: 508 PASKATS--DEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGE 565
ASKAT D S S+ K D + ++ Q+ +L K+
Sbjct: 1179 QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAA----------GMLSPKTGGKEAA 1228
Query: 566 KSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNI 625
T + P K + + + S L + T+ + + P EA + S +
Sbjct: 1229 SGTTPQKSRKPK-KGAGNPQASTLALQ-----SNITQCLLGQPWPLNEA--QVQASVVKV 1280
Query: 626 TREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSD 685
E + E + V + K + KG + + G D +RT S+K L A
Sbjct: 1281 LTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAARTPRSKKKKKLGAGEG 1334
Query: 686 EKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSD--EEDSVLSIARENKDGEKSRTVSSE 743
+ SV EKT T S K KA+ D E+ S+ + E E
Sbjct: 1335 GEASV--------SPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEE----E 1382
Query: 744 KPSGLKATSAEKDSVLNIARGKKYGEKTKR---VSSRKKPALKATSDEKDSVLYIAREKK 800
G+ S + KK +K K+ +KK A KA++ + +S ++KK
Sbjct: 1383 LQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKK 1442
Query: 801 DGEKSRTV 808
+TV
Sbjct: 1443 KKTAEQTV 1450
Score = 47.8 bits (112), Expect = 5e-05
Identities = 126/637 (19%), Positives = 238/637 (37%), Gaps = 96/637 (15%)
Query: 335 QKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS-KATSDKTDSALNIATEIKD 393
++QS +K + V+LL+I T + G ++ A+ +A + ++ + ++
Sbjct: 31 KEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEE 90
Query: 394 GLQCGTVSSQKQPALKATTDE---EDSVSNIATEIK-DGEKSG-TVSSQKQPALKATTDE 448
+ +++ P L +T D S++ + K + EK+G T +S PA T
Sbjct: 91 EEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT--- 147
Query: 449 KDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDG------------ 496
V+N+ + K KS S+ L + ++EEGSV + K G
Sbjct: 148 ---VANLLSG-KSPRKSAEPSANT--TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 497 ---------------------EKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI--- 532
K+ +VS+++ PA KA + ++T K G +
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKA-APAPGKVGDVTPQVKGGALPPA 260
Query: 533 --SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEK-----SRTVSSEKPPGLKASSDEK 585
++K + + +G+ EE++ G + K EK + + ++ PG A+
Sbjct: 261 KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPP 320
Query: 586 DSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEIS---------- 635
+A K G+ + S + S + + +E + + + K G+ S
Sbjct: 321 GKAGAVASQTKAGKPEEDSESSSEESSD-SEEETPAAKALLQAKASGKTSQVGAASAPAK 379
Query: 636 ---RKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLN 692
RK ++ PP G + + + G E+ + S E+ P S + V
Sbjct: 380 ESPRKGAAPAPPGKTGPAVAK-AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 693 IARGKKDGEKTRTVSSQKPP--------TLKATSDEEDSVLSIARENKDGE--KSRTVSS 742
+ K E R ++ PP ++ EEDS S + D E + +
Sbjct: 439 ASAPAK--ESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496
Query: 743 EKPSGLKATSAEKDSVLNIA-RGKKYGEKTKRVSSRKKPALKATSDEKDSVLYI--AREK 799
KP G K+ + S + + GK G P+ + E+DS + +
Sbjct: 497 VKPLG-KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 800 KDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQ---KQPALKATSDK 856
DGE V+ ++ +L I + P + K Q +G V+ Q ++P + S +
Sbjct: 556 SDGEVPTAVAPAQEKSLGNILQAK---PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 612
Query: 857 KDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVS 893
+ S S E + P + Q KK +
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 67.8 bits (164), Expect = 5e-11
Identities = 163/775 (21%), Positives = 292/775 (37%), Gaps = 138/775 (17%)
Query: 223 DSLTSSEESSE--RPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKD 280
D+ +SS+E+ +P + +K + S+K + RK +P PGK
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGK----------------- 244
Query: 281 SVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAR 340
V ++ ++K G + K+P E++ S E+ S E ++ +GT S Q +++
Sbjct: 245 -VGDVTPQVKGGALP-PAKRAKKPEEESESSEEGS------ESEEEAPAGTRS-QVKASE 295
Query: 341 KVIFKKKVSLLNIATRIMGG-----GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGL 395
K++ + S T G GK+G V+SQ + A K D S + E D
Sbjct: 296 KILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK-AGKPEEDSESS----SEESSD-- 348
Query: 396 QCGTVSSQKQPALKA-----TTDEEDSVSNIATEIKDGEKSGTVSS---QKQPAL-KATT 446
S ++ PA KA + + V + K+ + G + + PA+ KA
Sbjct: 349 -----SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQA 403
Query: 447 DEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRK 506
+++ S ++E D E ++ PA S + V + + K+ + +
Sbjct: 404 GKREEDSQSSSEESDSE-------EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
Query: 507 KPASKATS------DEKDSFSNITRGKKDGE-ISRKVSSQKPPTLKGTSDEEDSVLGIAR 559
+ A + E+DS S+ D E ++ ++Q P K + S +G+
Sbjct: 457 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516
Query: 560 ENKD-GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 618
K G P + E+DS + E++ S + P+ A + E
Sbjct: 517 LGKGAGPVPPGKVGPATPSAQVGKWEEDS-------ESSSEESSDSSDGEVPTAVAPAQE 569
Query: 619 KDSFSNITREK-----------KDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGE 667
K S NI + K K G ++ +V ++KP D +S E
Sbjct: 570 K-SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKP------MDNSES---------SEE 613
Query: 668 KSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLK-----------A 716
S + SE+ P + K + L I + K +KT T +S K ++ A
Sbjct: 614 SSDSADSEEAPAAMTAAQAKPA-LKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 717 TSDEEDSVLSIARENKDGEKS----RTVSSEKPSGLKATSAEKDSV--------LNIARG 764
TS S + E S + S E+ +GL T + SV ++
Sbjct: 673 TSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVK 732
Query: 765 KKYGEKTKRVSSRKK-PALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKE 823
G+ T V K P + EK + E+ D E++ +Q + ++K K
Sbjct: 733 GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKA 792
Query: 824 DSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSA 883
+ A K GT+S+ + A K+ S S + +++ Q S ++ S
Sbjct: 793 NPAAARAPSAK-----GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASV 847
Query: 884 QKVIFKKKVSLLNIATRITGGWK-SGTVIRQAIEHDECLCYTGIKPSDVLYESHA 937
V ++ A TG + SG+ ++ +E +KPS ++ A
Sbjct: 848 PSV----GKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRA 898
Score = 47.8 bits (112), Expect = 5e-05
Identities = 126/637 (19%), Positives = 238/637 (37%), Gaps = 96/637 (15%)
Query: 335 QKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS-KATSDKTDSALNIATEIKD 393
++QS +K + V+LL+I T + G ++ A+ +A + ++ + ++
Sbjct: 31 KEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEE 90
Query: 394 GLQCGTVSSQKQPALKATTDE---EDSVSNIATEIK-DGEKSG-TVSSQKQPALKATTDE 448
+ +++ P L +T D S++ + K + EK+G T +S PA T
Sbjct: 91 EEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT--- 147
Query: 449 KDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDG------------ 496
V+N+ + K KS S+ L + ++EEGSV + K G
Sbjct: 148 ---VANLLSG-KSPRKSAEPSANT--TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSE 201
Query: 497 ---------------------EKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI--- 532
K+ +VS+++ PA KA + ++T K G +
Sbjct: 202 DTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKA-APAPGKVGDVTPQVKGGALPPA 260
Query: 533 --SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEK-----SRTVSSEKPPGLKASSDEK 585
++K + + +G+ EE++ G + K EK + + ++ PG A+
Sbjct: 261 KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPP 320
Query: 586 DSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEIS---------- 635
+A K G+ + S + S + + +E + + + K G+ S
Sbjct: 321 GKAGAVASQTKAGKPEEDSESSSEESSD-SEEETPAAKALLQAKASGKTSQVGAASAPAK 379
Query: 636 ---RKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLN 692
RK ++ PP G + + + G E+ + S E+ P S + V
Sbjct: 380 ESPRKGAAPAPPGKTGPAVAK-AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 693 IARGKKDGEKTRTVSSQKPP--------TLKATSDEEDSVLSIARENKDGE--KSRTVSS 742
+ K E R ++ PP ++ EEDS S + D E + +
Sbjct: 439 ASAPAK--ESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQ 496
Query: 743 EKPSGLKATSAEKDSVLNIA-RGKKYGEKTKRVSSRKKPALKATSDEKDSVLYI--AREK 799
KP G K+ + S + + GK G P+ + E+DS + +
Sbjct: 497 VKPLG-KSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 800 KDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQ---KQPALKATSDK 856
DGE V+ ++ +L I + P + K Q +G V+ Q ++P + S +
Sbjct: 556 SDGEVPTAVAPAQEKSLGNILQAK---PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 612
Query: 857 KDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVS 893
+ S S E + P + Q KK +
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
Score = 44.7 bits (104), Expect = 4e-04
Identities = 76/365 (20%), Positives = 137/365 (37%), Gaps = 66/365 (18%)
Query: 222 MDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDS 281
MD+ SSEESS+ + AAM + P K+ K +K +
Sbjct: 605 MDNSESSEESSDSAD---------SEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAK 655
Query: 282 VSNIATEIKEGPISGTVSSQ-----------KQPAEKATSDEKDSVSNIATEIKKGQQSG 330
V+ + + +GT +S ++PAE ++S E+ +E +K +
Sbjct: 656 VAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESD-----SEEEKTGLAV 710
Query: 331 TVSPQKQSARKVIFKKKVSL-----LNIATRIMGGGKSGT----VSSQKQPASKATSDKT 381
TV Q +S K + K S+ L T + GK+G V ++KQ S+++ +++
Sbjct: 711 TVG-QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
Query: 382 DSA------LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVS 435
DS + T +K ++ + P+ K T V A + K S
Sbjct: 770 DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKP 829
Query: 436 SQKQP----------------------ALKATTDEKDSVSNIATEIKDGEKSGTVSSQKP 473
+ P A +A T ++ + E E++ T++ KP
Sbjct: 830 PVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKP 889
Query: 474 PALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEIS 533
T + + L+ A+E+ + T + P++ + DS S+ DGE
Sbjct: 890 SGKT---HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 946
Query: 534 RKVSS 538
V+S
Sbjct: 947 AAVTS 951
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 67.0 bits (162), Expect = 8e-11
Identities = 99/452 (21%), Positives = 171/452 (37%), Gaps = 77/452 (17%)
Query: 352 NIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKAT 411
N + G G SS ASK+ T+ + G++ +S P ++
Sbjct: 1195 NAVASVQNGPGGGPSSSSIGSASKSDESSTEETDKSRERSQCGVKAVNKASSTTPKGNSS 1254
Query: 412 TDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQ 471
S SN A + D EK +K+ ATT E + KDG+ +
Sbjct: 1255 NGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLG------KDGK-------E 1301
Query: 472 KPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGE 531
KP DE+ ARE K+ S ++K K KD T + +
Sbjct: 1302 KPKEERPNKDEK------ARETKERTPK---SDKEKEKFKKEEKAKDEKFKTTVPNAESK 1352
Query: 532 ISRKVSSQKPPTLKGTSDEEDSVLGIAREN-KDGEKSRTVSSEKPPGLKASSDEKDSVLN 590
+++ +K P+ + +E ++EN K GEK+ S K P ++ E +
Sbjct: 1353 STQEREREKEPSRERDIAKEMK----SKENVKGGEKTPVSGSLKSPVPRSDIPEPERE-- 1406
Query: 591 IARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTS 650
+K +++ + PS +T KDS E K+ ++ PP K
Sbjct: 1407 --------QKRRKIDTHPSPSHSSTV--KDSLI----ELKESSAKLYINHTPPPLSKSKE 1452
Query: 651 DEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQK 710
E D KD +KSR S E+ DEKD +K+ ++ + + ++
Sbjct: 1453 REMDK--------KDLDKSRERSREREK-----KDEKD--------RKERKRDHSNNDRE 1491
Query: 711 -PPTLKATSDEEDSVLSIAREN------------KDGEKSRTVSSEKPSGLKATSAEKDS 757
PP L EE+ + +++ KD EK+++ SS K G + +EK
Sbjct: 1492 VPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMD 1551
Query: 758 VLNIARGKKYGEKTKRVSSRKKPALKATSDEK 789
++ K+ +++ ++K +EK
Sbjct: 1552 KISSGGKKESRHDKEKIEKKEKRDSSGGKEEK 1583
Score = 51.2 bits (121), Expect = 4e-06
Identities = 103/457 (22%), Positives = 161/457 (35%), Gaps = 93/457 (20%)
Query: 229 EESSERPPLSTLTLKEADP--SSKAAM------RRKDSPPPGKVSS-QKQPAEKATSDDK 279
EE +RP L L + + S K+ M KD PP V+S Q P +S
Sbjct: 1154 EEKEKRPDLYALAMGYSGQLKSRKSYMIPENEFHHKDPPPRNAVASVQNGPGGGPSSSSI 1213
Query: 280 DSVSNIATEIKEGPISGTVSSQ---------KQPAEKATSDEKDSVSNIATEIKKGQQSG 330
S S E SQ K S +S SN +K+ +
Sbjct: 1214 GSASKSDESSTEETDKSRERSQCGVKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEK 1273
Query: 331 TVSPQKQSARKVIFKKKVSLLNIATRIMG-GGKSGTVSSQKQPASKAT--------SDKT 381
+K+ K+K R++G GK + KA SDK
Sbjct: 1274 GKEKEKEK------KEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKE 1327
Query: 382 DSALNIATEIKDGLQCGTV------SSQKQPALKATTDEEDSVSNIATE--IKDGEKSGT 433
+ KD TV S+Q++ K + E D + ++ +K GEK+
Sbjct: 1328 KEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTPV 1387
Query: 434 VSSQKQPALKATTDEKD------------SVSNIATEIKDGEKSGTVSSQK------PPA 475
S K P ++ E + S S+ +T +KD SS K PP
Sbjct: 1388 SGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSST-VKDSLIELKESSAKLYINHTPPP 1446
Query: 476 LTATSDEEGSVLSIARENKDGEKSRTVS-SRKKPASKATSDEKDSFSNITRGKKDGEISR 534
L+ + + E + KD +KSR S R+K K + K SN R
Sbjct: 1447 LSKSKERE-------MDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDR--------- 1490
Query: 535 KVSSQKPPTLKGTSDEEDSVLGIAREN------------KDGEKSRTVSSEKPPGLKASS 582
+ PP L EE+ +G+++ KD EK+++ SS K G +
Sbjct: 1491 ----EVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFK 1546
Query: 583 DEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEK 619
EK ++ K+ +++ ++K +EK
Sbjct: 1547 SEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEK 1583
Score = 37.7 bits (86), Expect = 0.051
Identities = 77/368 (20%), Positives = 138/368 (37%), Gaps = 66/368 (17%)
Query: 223 DSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSV 282
D E+ E+ + T EA K + P K ++ E+ DK+
Sbjct: 1270 DKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKE 1329
Query: 283 SNIATE-IKEGPISGTV------SSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQ 335
E K+ TV S+Q++ EK S E+D + + K+ + G +P
Sbjct: 1330 KFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKS--KENVKGGEKTPV 1387
Query: 336 KQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGL 395
S + + + + R K T P+ +S DS + E+K+
Sbjct: 1388 SGSLKSPVPRSDIP---EPEREQKRRKIDT-----HPSPSHSSTVKDSLI----ELKESS 1435
Query: 396 QCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNI 455
++ P K+ E D KD +KS S +++ DEKD
Sbjct: 1436 AKLYINHTPPPLSKSKEREMDK--------KDLDKSRERSRERE-----KKDEKDR---- 1478
Query: 456 ATEIKDGEKSGTVSSQK-PPALTATSDEEGSVLSIAR------------ENKDGEKSRTV 502
K+ ++ + + ++ PP LT EE + +++ KD EK+++
Sbjct: 1479 ----KERKRDHSNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSK 1534
Query: 503 SSRKKPASKATSDEK-DSFSNITRGKKDGEISR-KVSSQKPPTLKGTSDEEDSVLGIARE 560
SS K+ S + EK D S + GKK+ + K+ ++ G +E+ +
Sbjct: 1535 SSGKEKGSDSFKSEKMDKIS--SGGKKESRHDKEKIEKKEKRDSSGGKEEK-------KH 1585
Query: 561 NKDGEKSR 568
+K +K R
Sbjct: 1586 HKSSDKHR 1593
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 65.1 bits (157), Expect = 3e-10
Identities = 136/658 (20%), Positives = 250/658 (37%), Gaps = 85/658 (12%)
Query: 214 ISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEK 273
I+ +FL S +SE+ ++ T K+ K ++ + ++K P +
Sbjct: 926 IAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPERE 985
Query: 274 ATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVS 333
+ +IK G G S+K TS +KD +S+ A E G+ S
Sbjct: 986 EICHFPKGIK----QIKNGTTDGEKKSKK--IRDKTSKKKDELSDYA-EKSTGKGDSCDS 1038
Query: 334 PQKQSARKVIF---KKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALN-IAT 389
+ + ++ + KK+ LL ++R S ++K + + +D L I
Sbjct: 1039 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSS--DTEKYSMKEDGCNSSDKRLKRIEL 1096
Query: 390 EIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV--SSQKQPALKATTD 447
+ L + + Q ++ EE S N + + K V +K+ +L+ +T
Sbjct: 1097 RERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTK 1156
Query: 448 EK--DSVSNIATEIKDGEKS----GTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRT 501
K D S+ +++I+D +++ G+ QK +T E VLS
Sbjct: 1157 RKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT-----ENLVLSSHTGFCQSSGDEA 1211
Query: 502 VSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAREN 561
+S D+ D + I + EI +SS + G+SD+E
Sbjct: 1212 LSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDED----GSSDDEP--------- 1258
Query: 562 KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDS 621
++G+K +E+ PG + K+ V + + K R R SD +
Sbjct: 1259 EEGKKRTGKQNEENPG---DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG 1315
Query: 622 FSNITREKKDGEIS----RKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKP 677
T+ K+ E+ RKVSS+ + + +E V E++D ++ RT S++K
Sbjct: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDS---EDSDFQESGVSEEVSESEDEQRPRTRSAKK- 1371
Query: 678 PGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKS 737
A +E R K +K R + Q+ + + S+ E+ E K+ E+
Sbjct: 1372 ----AELEENQ------RSYKQKKKRRRIKVQEDSSSENKSNSEEE-----EEEKEEEEE 1416
Query: 738 RTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAR 797
E+ E D + +G+K K + + A +E++ IA
Sbjct: 1417 EEEEEEEEE-----EDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE 1471
Query: 798 EKKDGEKSRTV------SSQKQP-ALKAICDKEDSVP--------NMATEKKDEQISG 840
+++ EK R V S K P K + D+++ NM + K Q+ G
Sbjct: 1472 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDG 1529
Score = 57.4 bits (137), Expect = 6e-08
Identities = 147/695 (21%), Positives = 263/695 (37%), Gaps = 108/695 (15%)
Query: 228 SEESSERPPLST-LTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286
+E E+ LS + K+ SS +A+ D+P P K+ KQ + D D + I
Sbjct: 644 NETVKEKQKLSVPVRKKDKRNSSDSAI---DNPKPNKLPKSKQSETVDQNSDSDEMLAIL 700
Query: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKK 346
E+ S+ + + +D + +N T Q+G K K K
Sbjct: 701 KEV----------SRMSHSSSSDTDINEIHTNHKTLYDLKTQAG-----KDDKGKRKRKS 745
Query: 347 KVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQ- 405
S + T+ KS +S +K+ +++ S DS L EIK + G + K+
Sbjct: 746 STSGSDFDTKKGKSAKSSIISKKKR-QTQSESSNYDSELE--KEIKSMSKIGAARTTKKR 802
Query: 406 -PALK---ATTDEEDSVSNIATE----IKDGEKSGTVSSQKQPALKATTDEKDSVSNIAT 457
P K ++ DE+ S + + +K ++ + ++++ + + + +V T
Sbjct: 803 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT 862
Query: 458 --EIKDGEKSGTVSSQKPPALTATSDEEGSV--LSIARENKDGEKSRTVSSR-------- 505
E++D +S + S +E S L + + + EKS+ + ++
Sbjct: 863 IMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDG 922
Query: 506 ---------KKPASKATS--DEKDSFSNITRGKKDGEISRKV------------SSQKPP 542
KK S TS D+K S KK + +KV ++K P
Sbjct: 923 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP 982
Query: 543 TLKGTSDEEDSVLGIARENKDGEKS----RTVSSEKPPGLK---ASSDEKDSVLNIARGK 595
+ + I DGEK R +S+K L S K + + K
Sbjct: 983 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK 1042
Query: 596 K-----YGEKTKRV-----SSRKKPSLEATSDEKDSFSNITREKKDGEISR-KVSSQKPP 644
K YG + KR SSRK+ ++ EK S D + R ++ ++
Sbjct: 1043 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL 1102
Query: 645 ALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTR 704
+ K + E S + D E+S + +K + TS +K +V+ + K++ +T
Sbjct: 1103 SSKRNTKEIQS----GSSSSDAEESSEDNKKKK---QRTSSKKKAVI-VKEKKRNSLRTS 1154
Query: 705 TVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARG 764
T Q T ++SD ED +N GE S KP ++ VL+ G
Sbjct: 1155 TKRKQADITSSSSSDIEDD-----DQNSIGEGSSDEQKIKP-------VTENLVLSSHTG 1202
Query: 765 KKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKED 824
+ +S + D+ D IA++ E +SS + + D E
Sbjct: 1203 FCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGS----SDDEP 1258
Query: 825 SVPNMATEKKDEQISGTVSSQKQPALKATSDKKDS 859
T K++E+ G ++ Q ++ SD ++S
Sbjct: 1259 EEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEES 1293
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 65.1 bits (157), Expect = 3e-10
Identities = 136/658 (20%), Positives = 250/658 (37%), Gaps = 85/658 (12%)
Query: 214 ISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEK 273
I+ +FL S +SE+ ++ T K+ K ++ + ++K P +
Sbjct: 964 IAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPERE 1023
Query: 274 ATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVS 333
+ +IK G G S+K TS +KD +S+ A E G+ S
Sbjct: 1024 EICHFPKGIK----QIKNGTTDGEKKSKK--IRDKTSKKKDELSDYA-EKSTGKGDSCDS 1076
Query: 334 PQKQSARKVIF---KKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALN-IAT 389
+ + ++ + KK+ LL ++R S ++K + + +D L I
Sbjct: 1077 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSS--DTEKYSMKEDGCNSSDKRLKRIEL 1134
Query: 390 EIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV--SSQKQPALKATTD 447
+ L + + Q ++ EE S N + + K V +K+ +L+ +T
Sbjct: 1135 RERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTK 1194
Query: 448 EK--DSVSNIATEIKDGEKS----GTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRT 501
K D S+ +++I+D +++ G+ QK +T E VLS
Sbjct: 1195 RKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT-----ENLVLSSHTGFCQSSGDEA 1249
Query: 502 VSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAREN 561
+S D+ D + I + EI +SS + G+SD+E
Sbjct: 1250 LSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDED----GSSDDEP--------- 1296
Query: 562 KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDS 621
++G+K +E+ PG + K+ V + + K R R SD +
Sbjct: 1297 EEGKKRTGKQNEENPG---DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG 1353
Query: 622 FSNITREKKDGEIS----RKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKP 677
T+ K+ E+ RKVSS+ + + +E V E++D ++ RT S++K
Sbjct: 1354 EEKKTKPKEHKEVKGRNRRKVSSEDS---EDSDFQESGVSEEVSESEDEQRPRTRSAKK- 1409
Query: 678 PGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKS 737
A +E R K +K R + Q+ + + S+ E+ E K+ E+
Sbjct: 1410 ----AELEENQ------RSYKQKKKRRRIKVQEDSSSENKSNSEEE-----EEEKEEEEE 1454
Query: 738 RTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAR 797
E+ E D + +G+K K + + A +E++ IA
Sbjct: 1455 EEEEEEEEE-----EDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE 1509
Query: 798 EKKDGEKSRTV------SSQKQP-ALKAICDKEDSVP--------NMATEKKDEQISG 840
+++ EK R V S K P K + D+++ NM + K Q+ G
Sbjct: 1510 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDG 1567
Score = 57.4 bits (137), Expect = 6e-08
Identities = 147/695 (21%), Positives = 263/695 (37%), Gaps = 108/695 (15%)
Query: 228 SEESSERPPLST-LTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286
+E E+ LS + K+ SS +A+ D+P P K+ KQ + D D + I
Sbjct: 682 NETVKEKQKLSVPVRKKDKRNSSDSAI---DNPKPNKLPKSKQSETVDQNSDSDEMLAIL 738
Query: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKK 346
E+ S+ + + +D + +N T Q+G K K K
Sbjct: 739 KEV----------SRMSHSSSSDTDINEIHTNHKTLYDLKTQAG-----KDDKGKRKRKS 783
Query: 347 KVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQ- 405
S + T+ KS +S +K+ +++ S DS L EIK + G + K+
Sbjct: 784 STSGSDFDTKKGKSAKSSIISKKKR-QTQSESSNYDSELE--KEIKSMSKIGAARTTKKR 840
Query: 406 -PALK---ATTDEEDSVSNIATE----IKDGEKSGTVSSQKQPALKATTDEKDSVSNIAT 457
P K ++ DE+ S + + +K ++ + ++++ + + + +V T
Sbjct: 841 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT 900
Query: 458 --EIKDGEKSGTVSSQKPPALTATSDEEGSV--LSIARENKDGEKSRTVSSR-------- 505
E++D +S + S +E S L + + + EKS+ + ++
Sbjct: 901 IMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDG 960
Query: 506 ---------KKPASKATS--DEKDSFSNITRGKKDGEISRKV------------SSQKPP 542
KK S TS D+K S KK + +KV ++K P
Sbjct: 961 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP 1020
Query: 543 TLKGTSDEEDSVLGIARENKDGEKS----RTVSSEKPPGLK---ASSDEKDSVLNIARGK 595
+ + I DGEK R +S+K L S K + + K
Sbjct: 1021 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK 1080
Query: 596 K-----YGEKTKRV-----SSRKKPSLEATSDEKDSFSNITREKKDGEISR-KVSSQKPP 644
K YG + KR SSRK+ ++ EK S D + R ++ ++
Sbjct: 1081 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL 1140
Query: 645 ALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTR 704
+ K + E S + D E+S + +K + TS +K +V+ + K++ +T
Sbjct: 1141 SSKRNTKEIQS----GSSSSDAEESSEDNKKKK---QRTSSKKKAVI-VKEKKRNSLRTS 1192
Query: 705 TVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARG 764
T Q T ++SD ED +N GE S KP ++ VL+ G
Sbjct: 1193 TKRKQADITSSSSSDIEDD-----DQNSIGEGSSDEQKIKP-------VTENLVLSSHTG 1240
Query: 765 KKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKED 824
+ +S + D+ D IA++ E +SS + + D E
Sbjct: 1241 FCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGS----SDDEP 1296
Query: 825 SVPNMATEKKDEQISGTVSSQKQPALKATSDKKDS 859
T K++E+ G ++ Q ++ SD ++S
Sbjct: 1297 EEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEES 1331
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 64.7 bits (156), Expect = 4e-10
Identities = 121/542 (22%), Positives = 227/542 (41%), Gaps = 77/542 (14%)
Query: 409 KATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTV 468
K+T ++ S E +D K + S ++ +K +E++ NI T+ KD E +
Sbjct: 711 KSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERE---NIPTD-KDSEFT--- 763
Query: 469 SSQKPPALTATSDEEGSVLSIARENKDGEKSRT--VSSRKKPASKATSDEKDSFSNITRG 526
+L ++ EE L + + D EK S++KP ++ EKD + R
Sbjct: 764 ------SLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKD-IEKMERK 816
Query: 527 --KKDGEISRKVSSQKPPT-LKGTSD---EEDSVLGIARE--NKDGEKSRTVSSEKPPGL 578
+K+ +I + S+K L D E+D + E +K+GEKS+ ++ K
Sbjct: 817 TFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDD 876
Query: 579 KASSDEKDSVLNIARGKKYGEKTKRVS-SRKKPSLEATSDEKDSFSNITREK-----KDG 632
+ S EK ++ K+ EK + ++ S++K +E + + D+ EK KD
Sbjct: 877 REKSREK---MDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDR 933
Query: 633 EISRKVSSQKPPALKGTSDEEDSVLGIARENK----DGEKSRTVSSEKPPGLKATSDEKD 688
E+ +K S+ ++ T+ + I E K DG K++ EKP LK + KD
Sbjct: 934 ELDKKEKSRDKESINITNSKH-----IQEEKKSSIVDGNKAQ---HEKPLSLKEKT--KD 983
Query: 689 SVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGL 748
L GK+ +K + + K + +S+L + E D K ++ + K +
Sbjct: 984 EPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSE-ADKPKPKSSPASKDTRP 1042
Query: 749 KATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTV 808
K D ++ + + K + K EK I +++K+ ++R
Sbjct: 1043 KEKRLVNDDLMQTSFERMLSLKDLEIEQWHKK-----HKEK-----IKQKEKERLRNRNC 1092
Query: 809 SSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIK 868
K I DKE + + TE K+++++ + SS+ A KD+VSN +
Sbjct: 1093 LELK------IKDKEKT-KHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVD 1145
Query: 869 D------------GQQSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTVIRQAIE 916
S SP+ ++ + + + VS++++A+ + T R +E
Sbjct: 1146 TKNVMTLGKSSFVSDNSLNRSPRSENEKPGLSSRSVSMISVASSEDSCHTTVTTPRPPVE 1205
Query: 917 HD 918
+D
Sbjct: 1206 YD 1207
Score = 32.0 bits (71), Expect = 2.8
Identities = 51/258 (19%), Positives = 98/258 (37%), Gaps = 37/258 (14%)
Query: 278 DKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKK------------ 325
DK+ + TE K ++ + SS+ A KD+VSN + +
Sbjct: 1099 DKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFV 1158
Query: 326 GQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSAL 385
S SP+ ++ + + + VS++++A+ TV++ + P +D L
Sbjct: 1159 SDNSLNRSPRSENEKPGLSSRSVSMISVAS--SEDSCHTTVTTPRPPVEY----DSDFML 1212
Query: 386 NIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKAT 445
+ Q +S K PAL E DS++++ IK + +S +
Sbjct: 1213 ESSESQMSFSQSPFLSIAKSPALHER--ELDSLADLPERIKPPYANRLSTSHLR------ 1264
Query: 446 TDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSR 505
SV ++ I +G + V P++ ++ +S E+S S
Sbjct: 1265 ---SSSVEDVKLIISEGRPTIEVRRCSMPSVICEHTKQFQTIS--------EESNQGSLL 1313
Query: 506 KKPASKATSDEKDSFSNI 523
P + S + + FSN+
Sbjct: 1314 TVPGDTSPSPKPEVFSNV 1331
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 64.7 bits (156), Expect = 4e-10
Identities = 121/542 (22%), Positives = 227/542 (41%), Gaps = 77/542 (14%)
Query: 409 KATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTV 468
K+T ++ S E +D K + S ++ +K +E++ NI T+ KD E +
Sbjct: 734 KSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERE---NIPTD-KDSEFT--- 786
Query: 469 SSQKPPALTATSDEEGSVLSIARENKDGEKSRT--VSSRKKPASKATSDEKDSFSNITRG 526
+L ++ EE L + + D EK S++KP ++ EKD + R
Sbjct: 787 ------SLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKD-IEKMERK 839
Query: 527 --KKDGEISRKVSSQKPPT-LKGTSD---EEDSVLGIARE--NKDGEKSRTVSSEKPPGL 578
+K+ +I + S+K L D E+D + E +K+GEKS+ ++ K
Sbjct: 840 TFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDD 899
Query: 579 KASSDEKDSVLNIARGKKYGEKTKRVS-SRKKPSLEATSDEKDSFSNITREK-----KDG 632
+ S EK ++ K+ EK + ++ S++K +E + + D+ EK KD
Sbjct: 900 REKSREK---MDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDR 956
Query: 633 EISRKVSSQKPPALKGTSDEEDSVLGIARENK----DGEKSRTVSSEKPPGLKATSDEKD 688
E+ +K S+ ++ T+ + I E K DG K++ EKP LK + KD
Sbjct: 957 ELDKKEKSRDKESINITNSKH-----IQEEKKSSIVDGNKAQ---HEKPLSLKEKT--KD 1006
Query: 689 SVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGL 748
L GK+ +K + + K + +S+L + E D K ++ + K +
Sbjct: 1007 EPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSE-ADKPKPKSSPASKDTRP 1065
Query: 749 KATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTV 808
K D ++ + + K + K EK I +++K+ ++R
Sbjct: 1066 KEKRLVNDDLMQTSFERMLSLKDLEIEQWHKK-----HKEK-----IKQKEKERLRNRNC 1115
Query: 809 SSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIK 868
K I DKE + + TE K+++++ + SS+ A KD+VSN +
Sbjct: 1116 LELK------IKDKEKT-KHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVD 1168
Query: 869 D------------GQQSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTVIRQAIE 916
S SP+ ++ + + + VS++++A+ + T R +E
Sbjct: 1169 TKNVMTLGKSSFVSDNSLNRSPRSENEKPGLSSRSVSMISVASSEDSCHTTVTTPRPPVE 1228
Query: 917 HD 918
+D
Sbjct: 1229 YD 1230
Score = 32.0 bits (71), Expect = 2.8
Identities = 51/258 (19%), Positives = 98/258 (37%), Gaps = 37/258 (14%)
Query: 278 DKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKK------------ 325
DK+ + TE K ++ + SS+ A KD+VSN + +
Sbjct: 1122 DKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFV 1181
Query: 326 GQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSAL 385
S SP+ ++ + + + VS++++A+ TV++ + P +D L
Sbjct: 1182 SDNSLNRSPRSENEKPGLSSRSVSMISVAS--SEDSCHTTVTTPRPPVEY----DSDFML 1235
Query: 386 NIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKAT 445
+ Q +S K PAL E DS++++ IK + +S +
Sbjct: 1236 ESSESQMSFSQSPFLSIAKSPALHER--ELDSLADLPERIKPPYANRLSTSHLR------ 1287
Query: 446 TDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSR 505
SV ++ I +G + V P++ ++ +S E+S S
Sbjct: 1288 ---SSSVEDVKLIISEGRPTIEVRRCSMPSVICEHTKQFQTIS--------EESNQGSLL 1336
Query: 506 KKPASKATSDEKDSFSNI 523
P + S + + FSN+
Sbjct: 1337 TVPGDTSPSPKPEVFSNV 1354
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 64.3 bits (155), Expect = 5e-10
Identities = 134/656 (20%), Positives = 259/656 (39%), Gaps = 97/656 (14%)
Query: 277 DDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV--SNIATEIKKGQ------- 327
D++DS S+ ++ E S ++ +E TSD +D + + T+ + +
Sbjct: 21 DERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNAS 80
Query: 328 --QSGTVSPQKQSARKVIFKKKVSLLNIATRIMG--GGKSGTVSSQKQPASKATSDKTDS 383
+S + QK S + + + + + G S + ++K P S + +++ +
Sbjct: 81 DSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLN 140
Query: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
+E +D + S+ + K+ + ++ + +I D E S++ P +
Sbjct: 141 GHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSE------SEEPPRHQ 194
Query: 444 ATTDE-----KDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIAR----ENK 494
A+ E K +S+ +E + S++PP A SD E L R E++
Sbjct: 195 ASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQA-SDSENEELPKPRISDSESE 253
Query: 495 DGEKSRTVSSRKKPASK---ATSDEKDSFSNITRGKKDGEI-------SRKVSSQKPPTL 544
D + + S + K + S+ +D N ++ E+ S QK P
Sbjct: 254 DPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPA- 312
Query: 545 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRV 604
S+ ED+ + D + R E ++ S DS ++ KK+
Sbjct: 313 -SDSETEDASRHKQKPESDDDSDRENKGEDTE-MQNDSFHSDSHMD---RKKFHSSDSEE 367
Query: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKG--TSDEEDSVLGIARE 662
KK +++ DEK+ ++K +S +K A K SD +DS A
Sbjct: 368 EEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSD-SDAVS 426
Query: 663 NKDGEKSRTVSSE-KPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTL------K 715
+K G++ +T++S+ + K SD+K+ +KD + + S + L +
Sbjct: 427 DKSGKREKTIASDSEEEAGKELSDKKNE-------EKDLFGSDSESGNEEENLIADIFGE 479
Query: 716 ATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGK---------- 765
+ +EE+ +E+ + EK T E + + DS NI RGK
Sbjct: 480 SGDEEEEEFTGFNQEDLEEEKGETQVKE--------AEDSDSDDNIKRGKHMDFLSDFEM 531
Query: 766 ----KYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICD 821
K KR +R + +D+ S + I + + E+ R +++QK+PALK +
Sbjct: 532 MLQRKKSMSGKRRRNRDGGTFISDADDVVSAM-IVKMNEAAEEDRQLNNQKKPALKKLTL 590
Query: 822 KEDSVPNMATEKKDEQI--SGTVSSQKQ----------PALKATSDKKDSVSNIPT 865
V ++ + E SG +S+ K+ PALK + + +P+
Sbjct: 591 LPAVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLKILQELPS 646
Score = 55.8 bits (133), Expect = 2e-07
Identities = 109/491 (22%), Positives = 185/491 (37%), Gaps = 63/491 (12%)
Query: 388 ATEIKDGLQCGTVSSQ---KQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 444
AT ++D G+ +Q + T E N ++ +DG G + +
Sbjct: 16 ATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPL 75
Query: 445 TTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSS 504
+ DS S KD + S + +PPA SD E + N+ G S + +
Sbjct: 76 NLNASDSESEELHRQKDSD-SESEERAEPPA----SDSENEDV-----NQHGSDSESEET 125
Query: 505 RKKPASKATSDE------KDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 558
RK P S + ++E DS N GK S QK P S+ ED++
Sbjct: 126 RKLPGSDSENEELLNGHASDS-ENEDVGKHPASDSEIEELQKSPA--SDSETEDALKPQI 182
Query: 559 RENKDGEKSRTVSS----EKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEA 614
+++ E R +S E+PP + S E + + + S + P +A
Sbjct: 183 SDSESEEPPRHQASDSENEEPPKPRMSDSESEELPK--------PQVSDSESEEPPRHQA 234
Query: 615 TSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSS 674
+ E + D E S+ PP + SD E+ L R + D E S
Sbjct: 235 SDSENEELPK--PRISDSE------SEDPPRHQA-SDSENEELPKPRIS-DSE------S 278
Query: 675 EKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDG 734
E PP +A+ E + + + E QK P + S+ ED+ + D
Sbjct: 279 EDPPRNQASDSENEELPKPRVSDSESE-----GPQKGPA--SDSETEDASRHKQKPESDD 331
Query: 735 EKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLY 794
+ R E ++ S DS ++ KK+ KK + + DEK+
Sbjct: 332 DSDRENKGEDTE-MQNDSFHSDSHMD---RKKFHSSDSEEEEHKKQKMDSDEDEKEGEEE 387
Query: 795 IAREKKDGEKSRTVSSQKQPALKA--ICDKEDSVPNMATEKKDEQISGTVSSQKQPALKA 852
++K S + +K A K+ + D +DS + ++K ++ S ++ A K
Sbjct: 388 KVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKE 447
Query: 853 TSDKKDSVSNI 863
SDKK+ ++
Sbjct: 448 LSDKKNEEKDL 458
>gi|59814411 hypothetical protein LOC253725 [Homo sapiens]
Length = 1318
Score = 64.3 bits (155), Expect = 5e-10
Identities = 133/646 (20%), Positives = 241/646 (37%), Gaps = 81/646 (12%)
Query: 149 RRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTV 208
RRT S +NL A + + + GK L + E+ LFT
Sbjct: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGL------FDDEDEESDLFTEAS 382
Query: 209 KDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD---------PSSKAAMRRKDSP 259
+DR ++ + +SS + ++ P +++ D PS K ++ + P
Sbjct: 383 QDRQAGAS-----VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEP-QKPEQP 436
Query: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
P K P DD D + + P S+ + + D ++
Sbjct: 437 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP------SKTRKVQSTADIFGDEEGDL 490
Query: 320 ATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSD 379
E TVS ++ + +KKV+L K+ SS+ + SD
Sbjct: 491 FKEKAVASPEATVSQTDENKARA--EKKVTL--------SYSKNLKPSSETKTQKGLFSD 540
Query: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
+ DS +++ L+ ++ K P + D+ED N+ GT + ++
Sbjct: 541 EEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLF--------GGTAAKKQT 592
Query: 440 PALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSV-------LSIARE 492
+L+A +EK K+ +S +K AL +SDEE ++ S +R
Sbjct: 593 LSLQAQREEK-------------AKASELSKKKASALLFSSDEEWNIPASQTHLASDSRS 639
Query: 493 NKDGEKSRTVSSRKKPASKATS-DEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEE 551
+ S T+ S++ A K TS E+D ++ KD S+K + + + D
Sbjct: 640 KGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKD---SQKKTQRVSLLFEDDVDSG 696
Query: 552 DSVLGIAREN-KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKP 610
S+ G + K + SE PP L + +EK++ L + K E K S K
Sbjct: 697 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK--ESLKFG 754
Query: 611 SLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSR 670
+ EK+ +TR ++ + S P KGT +VL + E +D + +
Sbjct: 755 RTDVAESEKEGL--LTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQ 812
Query: 671 TV--SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPT-----LKATSDEEDS 723
+ + +K G D + + ++ + P K T E S
Sbjct: 813 NIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPS 872
Query: 724 VLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGE 769
V S+ +++D + + S+ K +KD +N + +K+ E
Sbjct: 873 VGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPE 918
Score = 60.5 bits (145), Expect = 7e-09
Identities = 160/821 (19%), Positives = 302/821 (36%), Gaps = 110/821 (13%)
Query: 106 DVLPPVEEAVDRCLYLLDRFAQPVT---------------KDKFALESENI----SEPYF 146
D++P V+EAV+ L +LD + + + + LE +++ PY
Sbjct: 128 DLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYL 187
Query: 147 TNRRTISQQSAENLDAACGIDKTENGNMFEDQ----NVDKEGKALPATGQKANVSPEQPP 202
+ +Q D G +E G++ D+ + ++E + + A+ S +
Sbjct: 188 IGSKLFMEQE----DVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQN 243
Query: 203 LFTHTVKDRDHISTRFLGGMDSLTSSEESSE---------RPPLSTLTLKEADPSSKA-- 251
T + D + G D SE+ E RP S T + +++
Sbjct: 244 QHTTQMSDEEEDD----DGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKG 299
Query: 252 -AMRRKDSPPPGKVSSQKQPAE--------KATSDDKDSVSNIATEIKEGPISGTVSSQK 302
AM R D P S + +P + + SDD++ ++ + S S
Sbjct: 300 DAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGG 359
Query: 303 Q-PAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGG 361
K D++D S++ TE + +Q+G ++ S+ K K +++
Sbjct: 360 LFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVF 419
Query: 362 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 421
+ +V S K+P S GL A + +
Sbjct: 420 GAASVPSLKEPQKPEQPTPRKSPYG---PPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKV 476
Query: 422 -ATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVS---SQKPPALT 477
+T G++ G + + KA + +VS EK T+S + KP + T
Sbjct: 477 QSTADIFGDEEGDLFKE-----KAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSET 531
Query: 478 AT-----SDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRG------ 526
T SDEE S + ++ K ++ K P S + D++D N+ G
Sbjct: 532 KTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQ 591
Query: 527 -------KKDGEISRKVSSQKPPTLKGTSDEEDSV-------LGIARENKDGEKSRTVSS 572
+++ + ++S +K L +SDEE ++ +R + S T+ S
Sbjct: 592 TLSLQAQREEKAKASELSKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQS 651
Query: 573 EKPPGLKASS----DEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 628
++ +K +S D++D + IA+ + +KT+RVS + +++ F +
Sbjct: 652 QEAKAVKKTSLFEEDKEDDLFAIAKDSQ--KKTQRVSLLFEDDVDSGG---SLFGSPPTS 706
Query: 629 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 688
++ S+ PP L +E+++ LG+ +K E ++ S K EK+
Sbjct: 707 VPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK--ESLKFGRTDVAESEKE 764
Query: 689 SVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTV----SSEK 744
+L R ++ K + S P K T +VLS+ E +D + + + E
Sbjct: 765 GLL--TRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEV 822
Query: 745 PSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEK 804
G + K + + + K ++ + T K + D E
Sbjct: 823 GKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDED 882
Query: 805 SRTVSSQKQPAL----KAICDKEDSVPNMATEKKDEQISGT 841
SS K L K + K+ SV + +K E I G+
Sbjct: 883 DDLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPESIQGS 923
Score = 46.2 bits (108), Expect = 1e-04
Identities = 107/518 (20%), Positives = 183/518 (35%), Gaps = 90/518 (17%)
Query: 403 QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDG 462
Q+ L + EE SV + I D E+ + + +E++ + T++ D
Sbjct: 196 QEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHT---TQMSDE 252
Query: 463 EKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSN 522
E+ L A S++E + EN ++SR S + A++ D
Sbjct: 253 EEDDDGCD-----LFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDE 307
Query: 523 ITRGKKDGEIS-RKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAS 581
GE RK +K + DEED++ PP L
Sbjct: 308 EPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFA------------------PPKL--- 346
Query: 582 SDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQ 641
+DE S G + S K + +E D F+ +++++ G ++ SS
Sbjct: 347 TDEDFSPFGSGGG---------LFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSS 397
Query: 642 KPPALK----------GTSDE--EDSVLGIARENKDGEKSRTVSSEKPP--GLKATSDEK 687
P K G +D SV + K + + S PP GL D
Sbjct: 398 SKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 457
Query: 688 DSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSG 747
D + KTR V S T DEE + +E TVS +
Sbjct: 458 DDDDFFSAPHSKPSKTRKVQS----TADIFGDEEGDLF---KEKAVASPEATVSQTDENK 510
Query: 748 LKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRT 807
+A EK L+ ++ K +TK SDE+DS + + K +
Sbjct: 511 ARA---EKKVTLSYSKNLKPSSETKTQKG-------LFSDEEDSEDLFSSQSASNLKGAS 560
Query: 808 VSSQKQPALKAICDKEDSVPN-------------MATEKKDEQISGTVSSQKQPALKATS 854
+ K P ++ D ED N + +++++ + +S +K AL +S
Sbjct: 561 LLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSS 620
Query: 855 DKKDSVSNIPTEIK-------DGQQSGTVSPQKQSAQK 885
D++ ++ T + + + SGT+ Q+ A K
Sbjct: 621 DEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 658
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 63.9 bits (154), Expect = 7e-10
Identities = 68/275 (24%), Positives = 110/275 (40%), Gaps = 38/275 (13%)
Query: 499 SRTVSSRKKPASKATS-DEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGI 557
S+ KK K T D DS S + +GKKD + + + K L D +
Sbjct: 109 SKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSK------ 162
Query: 558 ARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSD 617
+ KD EK + ++E S DEK KK +K K+ S++ K S +
Sbjct: 163 -KGKKDAEKGKDSATE-------SEDEKGGA------KKDNKKDKKDSNKGKDSATESEG 208
Query: 618 EKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKP 677
EK +KD + +K S + K ++ E +V ++++DG+K E
Sbjct: 209 EKGG------TEKDSKKGKKDSKKG----KDSAIELQAVKADEKKDEDGKKDANKGDE-- 256
Query: 678 PGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKS 737
+ D K I +GKKD +K + S +K S ++ + + KD EK
Sbjct: 257 -----SKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKE 311
Query: 738 RTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTK 772
S + A+KD+ N + +K K K
Sbjct: 312 SADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
Score = 57.8 bits (138), Expect = 5e-08
Identities = 70/282 (24%), Positives = 107/282 (37%), Gaps = 27/282 (9%)
Query: 603 RVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARE 662
R+S R L A + + K EI +K + K T+D E + +
Sbjct: 83 RISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKK--GEDKTTQKDTTDSESE---LKQG 137
Query: 663 NKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEED 722
KD +K + + K L A D K +GKKD EK + +++ +
Sbjct: 138 KKDSKKGKDIEKGKEEKLDAKKDSK-------KGKKDAEKGKDSATESEDEKGGAKKDNK 190
Query: 723 SVLSIARENKD------GEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSS 776
+ + KD GEK T K G K + KDS + + K K+
Sbjct: 191 KDKKDSNKGKDSATESEGEKGGTEKDSK-KGKKDSKKGKDSAIELQAVKA---DEKKDED 246
Query: 777 RKKPALKA--TSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKK 834
KK A K + D K I + KKD +K + S + +K K+ + KK
Sbjct: 247 GKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKK 306
Query: 835 DEQISGTVSSQKQPALKATSD-KKDSVSNI-PTEIKDGQQSG 874
D + + S+K A D KKD+ N E KD ++ G
Sbjct: 307 DTE-KESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKG 347
Score = 55.8 bits (133), Expect = 2e-07
Identities = 58/239 (24%), Positives = 100/239 (41%), Gaps = 20/239 (8%)
Query: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK 472
D DS S + KD +K + K+ L A D K KD EK K
Sbjct: 126 DTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK-------KDAEKG------K 172
Query: 473 PPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEI 532
A + ++ G+ ++ KD K + ++ + T EKDS KK +
Sbjct: 173 DSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGT--EKDSKKGKKDSKKGKDS 230
Query: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEK-SRTVSSEKPPGLKASSDEKDSVLNI 591
+ ++ + K K ++D+ G E+KD +K ++ + K K SS + DS ++
Sbjct: 231 AIELQAVKADEKKDEDGKKDANKG--DESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDV 288
Query: 592 AR-GKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE-KKDGEISRKVSSQKPPALKG 648
+ KK K + ++K E+ +KD+ N ++ KKD + + K +K KG
Sbjct: 289 KKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKG 347
Score = 55.1 bits (131), Expect = 3e-07
Identities = 78/297 (26%), Positives = 123/297 (41%), Gaps = 57/297 (19%)
Query: 434 VSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIAREN 493
+++++QP T E DS A EI G+K ++QK T+D E + +
Sbjct: 92 LAARRQPLKPTRTVEVDSK---AAEI--GKKGEDKTTQKD-----TTDSESE---LKQGK 138
Query: 494 KDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGT-----S 548
KD +K + + K+ A D K +GKKD E + +++ G
Sbjct: 139 KDSKKGKDIEKGKEEKLDAKKDSK-------KGKKDAEKGKDSATESEDEKGGAKKDNKK 191
Query: 549 DEEDSVLG-IARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGK---KYGEKTKRV 604
D++DS G + +GEK T K G K S KDS + + K K E K+
Sbjct: 192 DKKDSNKGKDSATESEGEKGGTEKDSK-KGKKDSKKGKDSAIELQAVKADEKKDEDGKKD 250
Query: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENK 664
+++ S +A D K+ I + KKD +K SS SD +D V K
Sbjct: 251 ANKGDESKDAKKDAKE----IKKGKKD---KKKPSST-------DSDSKDDV------KK 290
Query: 665 DGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEE 721
+ +K T ++K +KD+ A KKD +K ++K A DE+
Sbjct: 291 ESKKDATKDAKKVA-------KKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEK 340
Score = 38.9 bits (89), Expect = 0.023
Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 25/235 (10%)
Query: 246 DPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPA 305
D S+ +KDS + K+ A D K + ++G S T S ++
Sbjct: 129 DSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK----DAEKGKDSATESEDEKGG 184
Query: 306 EKATS--DEKDSVS--NIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGG 361
K + D+KDS + ATE +G++ GT K+ +K K K S + +
Sbjct: 185 AKKDNKKDKKDSNKGKDSATE-SEGEKGGTEKDSKKG-KKDSKKGKDSAIELQAVKADEK 242
Query: 362 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 421
K K+ A+K D++ A A EIK G K+ K ++ + DS ++
Sbjct: 243 KD---EDGKKDANKG--DESKDAKKDAKEIKKG---------KKDKKKPSSTDSDSKDDV 288
Query: 422 ATEIK-DGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPA 475
E K D K ++K ++ +KD+ N + K K +K A
Sbjct: 289 KKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
Score = 38.5 bits (88), Expect = 0.030
Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 243 KEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQK 302
K+A+ ++ +KD+ ++ K+ +K +S D DS ++ E K+ K
Sbjct: 249 KDANKGDESKDAKKDAK---EIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAK 305
Query: 303 QPAEKATSD-EKDSVSNIATEIKKGQQSGTVSPQKQSARK 341
+ EK ++D +KD+ N + KK + +K+ A+K
Sbjct: 306 KDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKK 345
>gi|54124343 hypothetical protein LOC387680 [Homo sapiens]
Length = 1341
Score = 63.5 bits (153), Expect = 9e-10
Identities = 140/676 (20%), Positives = 251/676 (37%), Gaps = 93/676 (13%)
Query: 149 RRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTV 208
RRT S +NL A + + + GK L + E+ LFT
Sbjct: 329 RRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGL------FDDEDEESDLFTEAP 382
Query: 209 KDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD---------PSSKAAMRRKDSP 259
+DR ++ + +SS + ++ P +++ D PS K ++ + P
Sbjct: 383 QDRQAGAS-----VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEP-QKPEQP 436
Query: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDE-KDSVSN 318
P K P DD D + + P K ++T+D D +
Sbjct: 437 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP-------SKTGKVQSTADIFGDEEGD 489
Query: 319 IATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATS 378
+ E TVS ++ + +KKV+L K+ SS+ + S
Sbjct: 490 LFKEKAVASPEATVSQTDENKARA--EKKVTL--------SSSKNLKPSSETKTQKGLFS 539
Query: 379 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 438
D+ DS +++ L+ ++ K P L + D+ED N+ GT + ++
Sbjct: 540 DEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLF--------GGTAAKKQ 591
Query: 439 QPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGS---------VLSI 489
L+A +EK K+ +S +K AL +SDEE + S
Sbjct: 592 TLCLQAQREEK-------------AKASELSKKKASALLFSSDEEDQWNIPASQTHLASD 638
Query: 490 ARENKDGEKSRTVSSRKKPASKATS----DEKDSFSNITRGKKDGEISRKVSSQKPPTLK 545
+R + S T+ S++ A K TS DE+D I + S+K + + +
Sbjct: 639 SRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKD------SQKKTQRVSLLFE 692
Query: 546 GTSDEEDSVLGIAREN-KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRV 604
D S+ G + K + SE PP L + +EK++ L + K E K
Sbjct: 693 DDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK-- 750
Query: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENK 664
S K + EK+ +TR ++ + S P KGT +VL + E +
Sbjct: 751 ESLKFGRTDVAESEKEGL--LTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEE 808
Query: 665 DGEKSRTV--SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPT-----LKAT 717
D + + + + +K G D + + ++ + P K T
Sbjct: 809 DKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKT 868
Query: 718 SDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSR 777
E SV S+ +++D + + S+ K +KD ++ + +K+ E + S+
Sbjct: 869 KLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQ--GSK 926
Query: 778 KKPALKATSDEKDSVL 793
+K K + + S L
Sbjct: 927 EKGIWKPETPQDSSGL 942
Score = 45.1 bits (105), Expect = 3e-04
Identities = 97/474 (20%), Positives = 176/474 (37%), Gaps = 68/474 (14%)
Query: 471 QKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDG 530
Q+ L S EEGSV S ++ V + ++ + + ++ S+ + +
Sbjct: 196 QEDVGLGELSSEEGSVGS--------DRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTT 247
Query: 531 EISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLN 590
++S + L S++E+ + EN ++SR S + D V
Sbjct: 248 QMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDE 307
Query: 591 IARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKP-PALKGT 649
GE R + ++K SD+++ + D + S S KG
Sbjct: 308 EPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGL 367
Query: 650 SDEEDSVLGIARE----NKDGEKSRTVSSEKPPGLKATSDEKD------------SVLNI 693
D+ED + E + G + SS PG K + SV ++
Sbjct: 368 FDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSM 427
Query: 694 ARGKKDGEKTRTVSSQKPPTLKA----TSDEEDSVLSI--ARENKDGEKSRT--VSSEKP 745
+K + T S PP D++D S ++ +K G+ T + ++
Sbjct: 428 KEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE 487
Query: 746 SGL---KATSAEKDSVLNIARGKKYGEKTKRVSSRK--KPALKAT------SDEKDSVLY 794
L KA ++ + +V K EK +SS K KP+ + SDE+DS
Sbjct: 488 GDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDL 547
Query: 795 IAREKKDGEKSRTVSSQKQPALKAICDKEDSVPN-------------MATEKKDEQISGT 841
+ + K ++ K P L ++ D ED N + +++++ +
Sbjct: 548 FSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASE 607
Query: 842 VSSQKQPALKATSDKKDSVSNIPTEIK----------DGQQSGTVSPQKQSAQK 885
+S +K AL +SD++D NIP + + SGT+ Q+ A K
Sbjct: 608 LSKKKASALLFSSDEEDQ-WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 660
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 63.2 bits (152), Expect = 1e-09
Identities = 102/494 (20%), Positives = 192/494 (38%), Gaps = 55/494 (11%)
Query: 426 KDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGS 485
KD +K G S P K +EK N A + S+K + + T+ E +
Sbjct: 129 KDSKKKGG-SYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQN 187
Query: 486 VLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPT-- 543
++++ +K + +S KK ++ + + ++ R K + ++ S+
Sbjct: 188 SKTVSKNCSQKDKKDSKNS-KKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVD 246
Query: 544 ---LKGTSDEE----DSVLGIAREN--------------KDGEKSRTVSS--EKPPGLKA 580
L G SD+E D+ L +N KD +K+ SS E A
Sbjct: 247 FLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDA 306
Query: 581 SSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSS 640
D K N+ + K + K S S ++ + KD+ + + KKD +K +
Sbjct: 307 KKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKD---DKKKDT 363
Query: 641 QKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT-SDEKDSVLNIARGKKD 699
+K P + T E ++++ +K+ +K K T S + +S L +KD
Sbjct: 364 KKYP--ESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKD 421
Query: 700 GEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEK-----------SRTVSSEKPSGL 748
+K + S K K+ ++E+S + + D +K S+ +K +
Sbjct: 422 EKKDKKDS--KTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKK 479
Query: 749 KATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTV 808
A S E +S L + + KK+ ++ K S+K A D + + K G K+ T
Sbjct: 480 NAESTEMESDLELKKDKKHSKEKK--GSKKDIKKDARKDTESTDAEFDESSKTGFKTSTK 537
Query: 809 SSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSD-KKDSVSNIPTEI 867
+ E+S+ +KK ++ GT ++ K L++ + S E
Sbjct: 538 IKGSD------TESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEK 591
Query: 868 KDGQQSGTVSPQKQ 881
+ +G V P ++
Sbjct: 592 GEKASTGRVPPSRE 605
Score = 58.9 bits (141), Expect = 2e-08
Identities = 106/493 (21%), Positives = 199/493 (40%), Gaps = 51/493 (10%)
Query: 438 KQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTAT---SDEEGSVLSIARENK 494
K+ K + DEK K G T K T ++ + + L + EN+
Sbjct: 111 KKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENE 170
Query: 495 DGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPT-------LKGT 547
+KS++ SS P S+ + + S + KKD + S+K +++ T LK +
Sbjct: 171 QSKKSKS-SSETNPESQNSKTVSKNCSQ--KDKKDSKNSKKTNTEFLHTKNNPKKDLKRS 227
Query: 548 SDEEDSVLGIARENK---DGEKSRTVSSEKPPGLKA---SSDEKDSVLNIARGKKYGEKT 601
D + I EN D S ++ A + + +S + KY +K
Sbjct: 228 KTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKD 287
Query: 602 KRVSSRK------KPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDS 655
+ +++K + S +A D K N+ ++ K ++ + S + + +D+
Sbjct: 288 TKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDT 347
Query: 656 VLGIARENKDGEKSRTVSSEKPPGLKA--TSDEKDSVLNIARGKKDGEKTRTVSSQKPPT 713
+ KD +K T + ++ D ++ N+ + K+ +K + K T
Sbjct: 348 KKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKK---DAKKIT 404
Query: 714 LKATSDEE-DSVLSIARENKDGEKSRTVSSEK-PSGLKATSAEKDSVLNIARGK---KYG 768
S+ E +S S E KD + S+T + + + ++T A+ + + +GK K G
Sbjct: 405 FSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKG 464
Query: 769 EKTKRVSSRKKPALK-ATSDEKDSVLYIAREKKDG-EKSRTVSSQKQPALK--AICDKED 824
+K + +KK A K A S E +S L + ++KK EK + K+ A K D E
Sbjct: 465 KKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEF 524
Query: 825 SVPNMATEKKDEQISGTVSSQKQ----PALKATSDKKDSVSNIPTEIKDGQQSGTVSPQ- 879
+ K +I G+ + ++ P K D+ D S + + G S +
Sbjct: 525 DESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTS------ANSKMEGLESKRG 578
Query: 880 -KQSAQKVIFKKK 891
+ S++K F +K
Sbjct: 579 FRMSSKKTTFNEK 591
Score = 57.4 bits (137), Expect = 6e-08
Identities = 79/331 (23%), Positives = 122/331 (36%), Gaps = 20/331 (6%)
Query: 409 KATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTV 468
K ++D E S A + K K+ +K T+ D+ S + KD K
Sbjct: 293 KKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESG---DSKDERKDTKK 349
Query: 469 SSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKK 528
+K D + S E+ D + +R S K ASK +KD+
Sbjct: 350 DKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDS 409
Query: 529 DGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSE-KPPGLKASSDEKDS 587
+ E+ K S + D++DS + K+ E+S SE K K DEK
Sbjct: 410 ESELESKESQKDE-----KKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKG 464
Query: 588 VLNIAR-GKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
+ + KK K S+ + LE D+K S +EKK + K ++K
Sbjct: 465 KKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHS-----KEKKGSKKDIKKDARKDTES 519
Query: 647 KGTSDEEDSVLGIARENK-DGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRT 705
+E S G K G + + S PG K DE D A K +G +++
Sbjct: 520 TDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDG--TSANSKMEGLESK- 576
Query: 706 VSSQKPPTLKATSDEEDSVLSIARENKDGEK 736
+ + K T +E+ S R EK
Sbjct: 577 -RGFRMSSKKTTFNEKGEKASTGRVPPSREK 606
Score = 41.2 bits (95), Expect = 0.005
Identities = 64/328 (19%), Positives = 116/328 (35%), Gaps = 44/328 (13%)
Query: 362 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 421
K K+ K ++ TD+ + + + + +K K T +S
Sbjct: 314 KKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTE 373
Query: 422 ATEIKDGE------KSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPA 475
+ + KD K + + K+ K T DS S + ++ ++ K
Sbjct: 374 SGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDN 433
Query: 476 LTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRK 535
+ ++E S + + D +K + + K SK +KD+ N + + ++ K
Sbjct: 434 KKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELK 493
Query: 536 VSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGK 595
+ KG+ + + AR++ + + S K G K S+ K
Sbjct: 494 KDKKHSKEKKGSKKD---IKKDARKDTESTDAEFDESSK-TGFKTSTKIK---------- 539
Query: 596 KYGEKTKRVSSRKKPSLEATSDEKDSFS-NITREKKDGEISRKVSSQKPPALKGTSDEED 654
G T+ S KP + DE D S N E + + ++SS+K
Sbjct: 540 --GSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKK------------ 585
Query: 655 SVLGIARENKDGEKSRT----VSSEKPP 678
N+ GEK+ T S EKPP
Sbjct: 586 -----TTFNEKGEKASTGRVPPSREKPP 608
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 63.2 bits (152), Expect = 1e-09
Identities = 145/735 (19%), Positives = 275/735 (37%), Gaps = 84/735 (11%)
Query: 197 SPEQPPLFTHTVKDRDHIS--TRFLGGMDSLTSSEESSERPPLSTLT------------- 241
S +P F KD H+S T+ D+ + + +S++ S L
Sbjct: 378 STAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDS 437
Query: 242 --LKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVS 299
E PSS A S P S+ AE ++ D DS S+ E S + S
Sbjct: 438 EQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSD-----SESESSSSDS 492
Query: 300 SQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMG 359
+ +P E + + +N K Q ++ Q A + G
Sbjct: 493 EENEPLETPAPEPEPPTTN------KWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKG 546
Query: 360 GGKSGTVSSQKQPASKATSDKTDSALNIA---TEIKDGLQCGTVSSQKQPALKATTDEED 416
S T SQ+ SK K+ S A C +Q++P + T +
Sbjct: 547 SSDSAT--SQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ 604
Query: 417 SVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIK-DGEKSGTVSSQKPPA 475
+ + G ++ ++ +++P L +D S ++K G S++ PA
Sbjct: 605 PKKPVKASARAGSRT-SLQGEREPGL-LPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPA 662
Query: 476 LTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDE-KDSFSNITRGKKDGEISR 534
+ +S+++ S+ +K S +PA D + F+ + + G
Sbjct: 663 VPPSSEKKKHKSSLPAPSK-------ALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHS 715
Query: 535 KVSSQKPPTLKGTSDEEDSVLG-IARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIAR 593
S+ + +EDS + +D + + PP D + I +
Sbjct: 716 GSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQ 775
Query: 594 GKKYGEKTKRVSSRKKPSLEATSDEK---DSFSNITREKKDGEISRKVSSQKPPALKGTS 650
G + ++ ++ P+ + S EK DS S + +++K GE R ++K K
Sbjct: 776 PPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRK-GEAERDCDNKKIRLEKEIK 834
Query: 651 DEEDSVLGIARENKDGEKSR--TVSSEK---PPGLKATSDEKDSVLNIARGKKDGEKTRT 705
+ S +E+ + SR + SS+K PP ++S +K + + R +++ +
Sbjct: 835 SQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREAD---- 890
Query: 706 VSSQKPPTLKATSDEEDSVLSIARENK-DGEKSRTVSSEKPSGLKATSAEKDSVLNIARG 764
Q PP +++ SI ++ + +G+ SR+ S K G +A V ++ G
Sbjct: 891 TCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHK--GSSGDTANPFPVPSLPNG 948
Query: 765 KKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKED 824
S KP +K D++ + L++ KK +K+ ++ + A K +
Sbjct: 949 N---------SKPGKPQVK--FDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLS 997
Query: 825 SVP-NMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSA 883
+ +ATE S+ Q + A S ++V I + S +P ++
Sbjct: 998 FIECGIATE-----------SESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKI 1046
Query: 884 QKVIFKKKVSLLNIA 898
V+ + S+LN+A
Sbjct: 1047 FAVLCMRCQSILNMA 1061
Score = 36.2 bits (82), Expect = 0.15
Identities = 55/259 (21%), Positives = 92/259 (35%), Gaps = 40/259 (15%)
Query: 90 KLYIPKR--KIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESENISEPYFT 147
+L +P R K++SP ++D PP V L LL R QP K ++E+ P
Sbjct: 738 RLPLPLRDTKLLSP--LRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGK 795
Query: 148 NRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHT 207
+ + S D++ + K G D +K + E + +
Sbjct: 796 KHSSEKRSS----DSSSKLAKKRKGEAERD-----------CDNKKIRLEKEIKSQSSSS 840
Query: 208 VKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDS---PPPGKV 264
S S +S +E PP+S+ + K A P+ K + R D+ PP
Sbjct: 841 SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSA 900
Query: 265 SSQKQ---------------PAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKAT 309
SS K +++S+ K S + A P+ + +P +
Sbjct: 901 SSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPF---PVPSLPNGNSKPGKPQV 957
Query: 310 SDEKDSVSNIATEIKKGQQ 328
+K E KK +Q
Sbjct: 958 KFDKQQADLHMREAKKMKQ 976
Score = 35.8 bits (81), Expect = 0.19
Identities = 55/313 (17%), Positives = 121/313 (38%), Gaps = 20/313 (6%)
Query: 569 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEAT-------SDEKDS 621
T S+ +P + + V ++ + +K + + + S + + SD +DS
Sbjct: 376 TPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDS 435
Query: 622 FSNITREKKDGEISRKVSSQKPP-----ALKGTSDEEDSVLGIARENKDGEKSRTVSSEK 676
S T EK + + Q P A +++ E + + + + E S + S E
Sbjct: 436 DSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEEN 495
Query: 677 PPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEK 736
P + + N + + D T+ PP S E ++ + D
Sbjct: 496 EPLETPAPEPEPPTTN--KWQLDNWLTKVSQPAAPPE-GPRSTEPPRRHPESKGSSDSAT 552
Query: 737 SRTVSSEKPSGLKATSAEKDSVLNIAR-GKKYGEKTKRVSSRKKPALKATSDEKDSVLYI 795
S+ S K K++S + GK+ +K+ ++++P + T K +
Sbjct: 553 SQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSP---AQQEPPQRQTVGTKQPKKPV 609
Query: 796 AREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSD 855
+ G ++ ++ +++P L ++ + + K + S++ +PA+ +S+
Sbjct: 610 KASARAGSRT-SLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSE 668
Query: 856 KKDSVSNIPTEIK 868
KK S++P K
Sbjct: 669 KKKHKSSLPAPSK 681
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.120 0.311
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,269,031
Number of Sequences: 37866
Number of extensions: 1632602
Number of successful extensions: 8249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 609
Number of HSP's that attempted gapping in prelim test: 5437
Number of HSP's gapped (non-prelim): 2145
length of query: 948
length of database: 18,247,518
effective HSP length: 112
effective length of query: 836
effective length of database: 14,006,526
effective search space: 11709455736
effective search space used: 11709455736
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.