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Search of human proteins with 239753142
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239753142 PREDICTED: similar to unr-interacting protein
[Homo sapiens]
(347 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239753142 PREDICTED: similar to unr-interacting protein [Homo... 714 0.0
gi|239747708 PREDICTED: similar to unr-interacting protein [Homo... 714 0.0
gi|113412837 PREDICTED: similar to unr-interacting protein [Homo... 706 0.0
gi|148727341 serine/threonine kinase receptor associated protein... 620 e-178
gi|4503513 eukaryotic translation initiation factor 3, subunit 2... 73 3e-13
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 72 6e-13
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 72 6e-13
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 72 6e-13
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 70 2e-12
gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [... 66 4e-11
gi|26665869 WD repeat domain 51B [Homo sapiens] 65 1e-10
gi|32189425 WD repeat domain 69 [Homo sapiens] 64 3e-10
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 63 3e-10
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 63 3e-10
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 60 2e-09
gi|113865883 WD repeat domain 38 [Homo sapiens] 60 3e-09
gi|16554629 WD repeat domain 5 [Homo sapiens] 60 4e-09
gi|16554627 WD repeat domain 5 [Homo sapiens] 60 4e-09
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 59 5e-09
gi|21071067 TBP-associated factor 5 [Homo sapiens] 59 6e-09
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 59 8e-09
gi|153791298 mitogen-activated protein kinase organizer 1 [Homo ... 57 2e-08
gi|14150114 mitogen-activated protein kinase organizer 1 [Homo s... 57 2e-08
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 55 9e-08
gi|148536855 coatomer protein complex, subunit alpha isoform 1 [... 54 2e-07
gi|148536853 coatomer protein complex, subunit alpha isoform 2 [... 54 2e-07
gi|21536371 telomerase-associated protein 1 [Homo sapiens] 53 5e-07
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 52 8e-07
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 52 1e-06
gi|4502477 beta-transducin repeat containing protein isoform 2 [... 51 2e-06
>gi|239753142 PREDICTED: similar to unr-interacting protein [Homo
sapiens]
Length = 347
Score = 714 bits (1843), Expect = 0.0
Identities = 347/347 (100%), Positives = 347/347 (100%)
Query: 1 MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG 60
MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG
Sbjct: 1 MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG 60
Query: 61 AVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDK 120
AVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDK
Sbjct: 61 AVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDK 120
Query: 121 LLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSADDKTARLWDHATMTEVKSLNF 180
LLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSADDKTARLWDHATMTEVKSLNF
Sbjct: 121 LLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSADDKTARLWDHATMTEVKSLNF 180
Query: 181 NMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAGG 240
NMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAGG
Sbjct: 181 NMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAGG 240
Query: 241 EDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGLW 300
EDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGLW
Sbjct: 241 EDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGLW 300
Query: 301 KCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA 347
KCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA
Sbjct: 301 KCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA 347
>gi|239747708 PREDICTED: similar to unr-interacting protein [Homo
sapiens]
Length = 347
Score = 714 bits (1843), Expect = 0.0
Identities = 347/347 (100%), Positives = 347/347 (100%)
Query: 1 MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG 60
MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG
Sbjct: 1 MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG 60
Query: 61 AVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDK 120
AVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDK
Sbjct: 61 AVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDK 120
Query: 121 LLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSADDKTARLWDHATMTEVKSLNF 180
LLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSADDKTARLWDHATMTEVKSLNF
Sbjct: 121 LLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSADDKTARLWDHATMTEVKSLNF 180
Query: 181 NMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAGG 240
NMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAGG
Sbjct: 181 NMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAGG 240
Query: 241 EDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGLW 300
EDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGLW
Sbjct: 241 EDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGLW 300
Query: 301 KCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA 347
KCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA
Sbjct: 301 KCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA 347
>gi|113412837 PREDICTED: similar to unr-interacting protein [Homo
sapiens]
Length = 348
Score = 706 bits (1823), Expect = 0.0
Identities = 346/348 (99%), Positives = 346/348 (99%), Gaps = 1/348 (0%)
Query: 1 MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG 60
MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG
Sbjct: 1 MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG 60
Query: 61 AVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDK 120
AVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDK
Sbjct: 61 AVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDK 120
Query: 121 LLRMYDLNKPKARPKEISGHTSGIKKGL-WCSEDKQILSADDKTARLWDHATMTEVKSLN 179
LLRMYDLNKPKARPKEISGHTSGIKK L WCSEDKQILSADDKTARLWDHATMTEVKSLN
Sbjct: 121 LLRMYDLNKPKARPKEISGHTSGIKKRLLWCSEDKQILSADDKTARLWDHATMTEVKSLN 180
Query: 180 FNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAG 239
FNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAG
Sbjct: 181 FNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAG 240
Query: 240 GEDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGL 299
GEDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGL
Sbjct: 241 GEDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGL 300
Query: 300 WKCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA 347
WKCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA
Sbjct: 301 WKCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA 348
>gi|148727341 serine/threonine kinase receptor associated protein
[Homo sapiens]
Length = 350
Score = 620 bits (1599), Expect = e-178
Identities = 312/350 (89%), Positives = 322/350 (92%), Gaps = 3/350 (0%)
Query: 1 MAMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKG 60
MAMRQT LT GHT P+VDLAFSGIT YGYFL SA KDGKPMLRQGDTGDWIGTF GHKG
Sbjct: 1 MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKG 60
Query: 61 AVWGATLN--ATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQ 118
AVWGATLN ATKAATAAADFTAKVWDAV GDELMTLAHK+IVKTV F QDSNYLLT GQ
Sbjct: 61 AVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQ 120
Query: 119 DKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSADDKTARLWDHATMTEVKSL 178
DKLLR+YDLNKP+A PKEISGHTSGIKK LWCSEDKQILSADDKT RLWDHATMTEVKSL
Sbjct: 121 DKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSL 180
Query: 179 NFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVA 238
NFNMSVSS +YIPEGEILVITYG SIAFHSAVSLDPI SFEAPATINSASLHPEKEFLVA
Sbjct: 181 NFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVA 240
Query: 239 GGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTY 297
GGEDFKLYKY +N GEE ESYKG+FGPIHCVRFS DGELYASGSEDGTLRL QTVVGKTY
Sbjct: 241 GGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTY 300
Query: 298 GLWKCVLPEEESGELAKPKIGFPETTEEELEEIVSEDSDCIYSSTPDVKA 347
GLWKCVLPEE+SGELAKPKIGFPETTEEELEEI SE+SDCI+ S PDVKA
Sbjct: 301 GLWKCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA 350
>gi|4503513 eukaryotic translation initiation factor 3, subunit 2
beta, 36kDa [Homo sapiens]
Length = 325
Score = 73.2 bits (178), Expect = 3e-13
Identities = 67/276 (24%), Positives = 112/276 (40%), Gaps = 42/276 (15%)
Query: 49 GDWIGTFWGHKGAVW--GATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYF 106
G+ +GT+ GH GAVW A + T +AD + ++WD G +L L V+T F
Sbjct: 42 GERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGF 101
Query: 107 MQDSNYLLTK-----GQDKLLRMYDLNKPKARPK-----EISGHTSGIKKGLWCSEDKQI 156
N ++ G + +DL P +I + S I +W + I
Sbjct: 102 DFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNEPYMKIPCNDSKITSAVWGPLGECI 161
Query: 157 LSADDKTARLWDHATMTEV--------KSLN-FNMSVSSTKYIPEGEILVITYGLSIAFH 207
++ + A EV + +N +S T ++ + +
Sbjct: 162 IAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASK------DNTAKLF 215
Query: 208 SAVSLDPITSFEAPATINSASLHPEKEFLVAGGEDFKL---------------YKYFNHG 252
+ +L+ +F +NSA+L P + +V GG + + +
Sbjct: 216 DSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFE 275
Query: 253 EEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRL 288
EEF KG+FGPI+ V F DG+ Y+SG EDG +R+
Sbjct: 276 EEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRI 311
Score = 50.4 bits (119), Expect = 2e-06
Identities = 52/217 (23%), Positives = 97/217 (44%), Gaps = 26/217 (11%)
Query: 92 LMTLAHKYIVKTVYFMQDSNYLLTKGQDKLLRM-YDLNKPKARPKEISGHTSGIKKGLWC 150
++ H+ + + + ++ + L T +D ++ + Y +N R GHT + WC
Sbjct: 4 ILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGE--RLGTYMGHTGAV----WC 57
Query: 151 SE----DKQILSAD-DKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIA 205
+ K +L+ D + RLWD T ++ L N +V + + G I++ + +
Sbjct: 58 VDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMG 117
Query: 206 FHSAVSL----DP--ITSFEA-------PATINSASLHPEKEFLVAGGEDFKLYKYF-NH 251
+ VS DP I + E + I SA P E ++AG E +L +Y
Sbjct: 118 YQCFVSFFDLRDPSQIDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKS 177
Query: 252 GEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRL 288
GE + K + I+ ++ SRD ++ + S+D T +L
Sbjct: 178 GEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKL 214
Score = 32.7 bits (73), Expect = 0.49
Identities = 18/54 (33%), Positives = 25/54 (46%)
Query: 248 YFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGLWK 301
Y +GE +Y G+ G + CV D + +GS D + RL GK L K
Sbjct: 38 YSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLK 91
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 72.4 bits (176), Expect = 6e-13
Identities = 64/242 (26%), Positives = 106/242 (43%), Gaps = 19/242 (7%)
Query: 55 FWGHKGAVWGATLNATK--AATAAADFTAKVW-DAVLGDELMTLAHKYIVKTVYFMQDSN 111
F GHK AV + + A+ + D T ++W V G+ + AH V++V+F D
Sbjct: 19 FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQ 78
Query: 112 YLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSA-DDKTARLWDHA 170
+T DK ++++ ++ K +S H + ++ + + + I+SA DDKT +LWD +
Sbjct: 79 SFVTASDDKTVKVWATHRQKFL-FSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS 137
Query: 171 TMTEVKSL-NFNMSVSSTKYIPEGEILVITYGLS-------IAFHSAVSLDPITSFEAPA 222
+ V S V+ + P G + G+ + H + + S A
Sbjct: 138 SRECVHSYCEHGGFVTYVDFHPSGTCIAAA-GMDNTVKVWDVRTHRLLQHYQLHS----A 192
Query: 223 TINSASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDGELYASGS 281
+N S HP +L+ D L G + G+ GP V FSR GE +ASG
Sbjct: 193 AVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 252
Query: 282 ED 283
D
Sbjct: 253 SD 254
Score = 34.7 bits (78), Expect = 0.13
Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Query: 222 ATINSASLHPEKEFLVAGGEDFKLYKYFNHGEEFE-SYKGYFGPIHCVRFSRDGELYASG 280
AT+ S + + V +D + + H ++F S + + C +FS DG L S
Sbjct: 66 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSA 125
Query: 281 SEDGTLRL 288
S+D T++L
Sbjct: 126 SDDKTVKL 133
Score = 32.0 bits (71), Expect = 0.84
Identities = 14/31 (45%), Positives = 19/31 (61%)
Query: 258 YKGYFGPIHCVRFSRDGELYASGSEDGTLRL 288
+ G+ + CV FS G L ASGS D T+R+
Sbjct: 19 FTGHKDAVTCVNFSPSGHLLASGSRDKTVRI 49
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 72.4 bits (176), Expect = 6e-13
Identities = 64/242 (26%), Positives = 106/242 (43%), Gaps = 19/242 (7%)
Query: 55 FWGHKGAVWGATLNATK--AATAAADFTAKVW-DAVLGDELMTLAHKYIVKTVYFMQDSN 111
F GHK AV + + A+ + D T ++W V G+ + AH V++V+F D
Sbjct: 57 FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQ 116
Query: 112 YLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSA-DDKTARLWDHA 170
+T DK ++++ ++ K +S H + ++ + + + I+SA DDKT +LWD +
Sbjct: 117 SFVTASDDKTVKVWATHRQKFL-FSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS 175
Query: 171 TMTEVKSL-NFNMSVSSTKYIPEGEILVITYGLS-------IAFHSAVSLDPITSFEAPA 222
+ V S V+ + P G + G+ + H + + S A
Sbjct: 176 SRECVHSYCEHGGFVTYVDFHPSGTCIAAA-GMDNTVKVWDVRTHRLLQHYQLHS----A 230
Query: 223 TINSASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDGELYASGS 281
+N S HP +L+ D L G + G+ GP V FSR GE +ASG
Sbjct: 231 AVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 290
Query: 282 ED 283
D
Sbjct: 291 SD 292
Score = 37.4 bits (85), Expect = 0.020
Identities = 42/194 (21%), Positives = 72/194 (37%), Gaps = 42/194 (21%)
Query: 97 HKYIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQI 156
H+ V V F ++ L + D L ++ + KP++R +GH + + +
Sbjct: 18 HRDAVTCVDFSINTKQLASGSMDSCLMVWHM-KPQSRAYRFTGHKDAVTCVNFSPSGHLL 76
Query: 157 LSAD-DKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPI 215
S DKT R+W V + K G S F +
Sbjct: 77 ASGSRDKTVRIW----------------VPNVK------------GESTVFRAHT----- 103
Query: 216 TSFEAPATINSASLHPEKEFLVAGGEDFKLYKYFNHGEEFE-SYKGYFGPIHCVRFSRDG 274
AT+ S + + V +D + + H ++F S + + C +FS DG
Sbjct: 104 ------ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDG 157
Query: 275 ELYASGSEDGTLRL 288
L S S+D T++L
Sbjct: 158 RLIVSASDDKTVKL 171
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 72.4 bits (176), Expect = 6e-13
Identities = 64/242 (26%), Positives = 106/242 (43%), Gaps = 19/242 (7%)
Query: 55 FWGHKGAVWGATLNATK--AATAAADFTAKVW-DAVLGDELMTLAHKYIVKTVYFMQDSN 111
F GHK AV + + A+ + D T ++W V G+ + AH V++V+F D
Sbjct: 57 FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQ 116
Query: 112 YLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSA-DDKTARLWDHA 170
+T DK ++++ ++ K +S H + ++ + + + I+SA DDKT +LWD +
Sbjct: 117 SFVTASDDKTVKVWATHRQKFL-FSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS 175
Query: 171 TMTEVKSL-NFNMSVSSTKYIPEGEILVITYGLS-------IAFHSAVSLDPITSFEAPA 222
+ V S V+ + P G + G+ + H + + S A
Sbjct: 176 SRECVHSYCEHGGFVTYVDFHPSGTCIAAA-GMDNTVKVWDVRTHRLLQHYQLHS----A 230
Query: 223 TINSASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDGELYASGS 281
+N S HP +L+ D L G + G+ GP V FSR GE +ASG
Sbjct: 231 AVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGG 290
Query: 282 ED 283
D
Sbjct: 291 SD 292
Score = 37.4 bits (85), Expect = 0.020
Identities = 42/194 (21%), Positives = 72/194 (37%), Gaps = 42/194 (21%)
Query: 97 HKYIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQI 156
H+ V V F ++ L + D L ++ + KP++R +GH + + +
Sbjct: 18 HRDAVTCVDFSINTKQLASGSMDSCLMVWHM-KPQSRAYRFTGHKDAVTCVNFSPSGHLL 76
Query: 157 LSAD-DKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPI 215
S DKT R+W V + K G S F +
Sbjct: 77 ASGSRDKTVRIW----------------VPNVK------------GESTVFRAHT----- 103
Query: 216 TSFEAPATINSASLHPEKEFLVAGGEDFKLYKYFNHGEEFE-SYKGYFGPIHCVRFSRDG 274
AT+ S + + V +D + + H ++F S + + C +FS DG
Sbjct: 104 ------ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDG 157
Query: 275 ELYASGSEDGTLRL 288
L S S+D T++L
Sbjct: 158 RLIVSASDDKTVKL 171
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 70.5 bits (171), Expect = 2e-12
Identities = 58/222 (26%), Positives = 96/222 (43%), Gaps = 6/222 (2%)
Query: 71 KAATAAADFTAKVWDAVLGDELMTL-AHKYIVKTVYFMQDSNYLLTKGQDKLLRMYDLNK 129
K AT++ D T K+WD GD ++T H V + + N++ + DK +++D+N
Sbjct: 408 KLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS 467
Query: 130 PKARPKEISGHTSGIKKGLWCSEDKQIL-SADDKTARLWDHATMTEVKSLNFNM-SVSST 187
+ R + GHT + + +L S+ DKT +WD T +SL +M S++
Sbjct: 468 ERCRCT-LYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDA 526
Query: 188 KYIPEGEILVITYGLSIA-FHSAVSLDPITSFE-APATINSASLHPEKEFLVAGGEDFKL 245
+ P G ++ + L PI S + P+ N + L + +
Sbjct: 527 IFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVI 586
Query: 246 YKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLR 287
+ E G+ H V FS DGE+ SG DGT+R
Sbjct: 587 HLLDLKSGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVR 628
>gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)
[Homo sapiens]
Length = 514
Score = 66.2 bits (160), Expect = 4e-11
Identities = 59/220 (26%), Positives = 99/220 (45%), Gaps = 7/220 (3%)
Query: 74 TAAADFTAKVWDAVLGDELMTLA-HKYIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKA 132
T +AD T K+WD G ++L H V+ V S YL + G+DK ++ +DL K
Sbjct: 221 TGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKV 280
Query: 133 RPKEISGHTSGIKK-GLWCSEDKQILSADDKTARLWDHATMTEVKSLNFNMSVSSTKYIP 191
+ GH S + L + D + + D TAR+WD T V +L+ + + +T
Sbjct: 281 I-RHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 339
Query: 192 EGEILVIT--YGLSIAFHSAVS-LDPITSFEAPATINSASLHPEKEFLVAGGEDFKLYKY 248
E +IT + +I V+ +T ++ + LHP +G D
Sbjct: 340 AAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWK 399
Query: 249 FNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRL 288
F G ++ G+ I+ + + DG L SG+++GT+ L
Sbjct: 400 FPDGSFIQNLSGHNAIINTLTVNSDGVL-VSGADNGTMHL 438
Score = 38.1 bits (87), Expect = 0.012
Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 5/123 (4%)
Query: 52 IGTFWGHKGAVWGATLNATKAA--TAAADFTAKVWDAVLGDELMTLA-HKYIVKTVYFMQ 108
+ T GH AV A + T + D T ++WD V G +TL HK V+ V +
Sbjct: 323 VHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVV-LH 381
Query: 109 DSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSADDKTARLWD 168
+Y G ++ + + + +SGH + I S+ + AD+ T LWD
Sbjct: 382 PRHYTFASGSPDNIKQWKF-PDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTMHLWD 440
Query: 169 HAT 171
T
Sbjct: 441 WRT 443
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 64.7 bits (156), Expect = 1e-10
Identities = 60/246 (24%), Positives = 108/246 (43%), Gaps = 15/246 (6%)
Query: 57 GHKGAVWGATLN--ATKAATAAADFTAKVWDAVLGDELMTL-AHKYIVKTVYFMQDSNYL 113
GHK V + A+A+ D T ++W + AH V++V F D +L
Sbjct: 58 GHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFL 117
Query: 114 LTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILS-ADDKTARLWDHATM 172
T +DK ++++ + + + + HT ++ + + + I+S ++DKT ++WD
Sbjct: 118 ATASEDKSIKVWSMYRQRFL-YSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNK 176
Query: 173 TEVKSLNFNMSVSSTKYI---PEGEILVITYGLSIAFHSAVSLDPITSFEAPAT--INSA 227
V NF+ SV ++ P G + V ++ + + +N
Sbjct: 177 QCVN--NFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCI 234
Query: 228 SLHPEKEFLVAGGEDFKLYKYFN--HGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGT 285
S HP +L+ D L K + G + +G+ GP+ V FS+ GEL+ASG D
Sbjct: 235 SFHPSGNYLITASSDGTL-KILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQ 293
Query: 286 LRLGQT 291
+ L +T
Sbjct: 294 VLLWRT 299
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/250 (22%), Positives = 113/250 (45%), Gaps = 11/250 (4%)
Query: 55 FWGHKGAVWGATL--NATKAATAAADFTAKVWD-AVLGDELMTLAHKYIVKTVYFMQDSN 111
F GHK A+ L N + ATA+ D +W+ + HK +V +V F N
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 112 YLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILS--ADDKTARLWDH 169
L + +D+ +R++ +K + + E HT+ ++ + S D Q L+ ++DK+ ++W
Sbjct: 74 LLASASRDRTVRLWIPDK-RGKFSEFKAHTAPVRS-VDFSADGQFLATASEDKSIKVWSM 131
Query: 170 ATMTEVKSLNFNMS-VSSTKYIPEGEILV-ITYGLSIAFHSAVSLDPITSF-EAPATINS 226
+ SL + V K+ P+G ++V + +I + + +F ++ N
Sbjct: 132 YRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANF 191
Query: 227 ASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGT 285
+P + + G D + + + + Y+ + G ++C+ F G + S DGT
Sbjct: 192 VDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGT 251
Query: 286 LRLGQTVVGK 295
L++ + G+
Sbjct: 252 LKILDLLEGR 261
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 63.5 bits (153), Expect = 3e-10
Identities = 72/296 (24%), Positives = 129/296 (43%), Gaps = 13/296 (4%)
Query: 2 AMRQTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKGA 61
A + L T GH + +AF+ YG + + D L +TG TF GH
Sbjct: 122 ASGEELNTLEGHRNVVYAIAFNN--PYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAE 179
Query: 62 VWGATLN--ATKAATAAADFTAKVWDAVLGDELMTL-AHKYIVKTVYFMQDSNYLLTKGQ 118
+ + N +T AT + D TAK+WD G+E+ TL H + ++ F + ++T
Sbjct: 180 IVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSF 239
Query: 119 DKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLWDHATMTEVKS 177
D + ++D + + + + GH + I + + IL+ DKT +LWD V +
Sbjct: 240 DHTVVVWDADTGR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVAT 298
Query: 178 L-NFNMSVSSTKYIPEGEILVITYGLSIA-FHSAVSLDPITSFEA-PATINSASLHPEKE 234
L + + + + G+++ A SA + I E I+ S +P+
Sbjct: 299 LTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGN 358
Query: 235 FLVAGGEDFKLYKYFN--HGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRL 288
L+ G D K + ++ G+ + +G+ I F+ G + +GS+D T R+
Sbjct: 359 HLLTGSSD-KTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRI 413
Score = 51.2 bits (121), Expect = 1e-06
Identities = 67/254 (26%), Positives = 108/254 (42%), Gaps = 25/254 (9%)
Query: 74 TAAADFTAKVWDAVLGDELMTL-AHKYIVKTVYFMQD-SNYLLTKGQDKLLRMYDLNKPK 131
T + D T K+WD G+EL TL H+ +V + F + + T DK +++ + K
Sbjct: 109 TGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGK 168
Query: 132 ARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLWDHATMTEVKSL-NFNMSVSSTKY 189
GHT+ I + + + + D TA+LWD EV +L + + S +
Sbjct: 169 CY-HTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSF 227
Query: 190 IPEGEILVITYGLSIAFHSAVSLDPITSFEAP------ATINSASLHPEKEFLVAGGED- 242
G+ +IT H+ V D T + A I+SAS + + ++ G D
Sbjct: 228 NTSGD-RIITGSFD---HTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDK 283
Query: 243 -FKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTYGLWK 301
KL+ N G+ + G+ I F G+L A+ S DGT R+ K
Sbjct: 284 TCKLWDATN-GKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATR------K 336
Query: 302 CVLP-EEESGELAK 314
C+ E GE++K
Sbjct: 337 CIAKLEGHEGEISK 350
Score = 32.7 bits (73), Expect = 0.49
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 19/152 (12%)
Query: 156 ILSADDKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPI 215
I + D+T +LWD A+ E+ +L + +V YG IA S +
Sbjct: 108 ITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNN------PYGDKIATGSFDKTCKL 161
Query: 216 TSFEA----------PATINSASLHPEKEFLVAGGED--FKLYKYFNHGEEFESYKGYFG 263
S E A I S +P+ + G D KL+ N GEE + +G+
Sbjct: 162 WSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN-GEEVYTLRGHSA 220
Query: 264 PIHCVRFSRDGELYASGSEDGTLRLGQTVVGK 295
I + F+ G+ +GS D T+ + G+
Sbjct: 221 EIISLSFNTSGDRIITGSFDHTVVVWDADTGR 252
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 63.2 bits (152), Expect = 3e-10
Identities = 56/223 (25%), Positives = 99/223 (44%), Gaps = 31/223 (13%)
Query: 73 ATAAADFTAKVWDAVLGDELMTL-AHKYIVKTVYFMQDSNYLL--TKGQDKLLRMYDLNK 129
AT + D K+W+++ G+ + T H V +F S++LL T D L+++DLN+
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQ 732
Query: 130 PKARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLWDHATMTEVKSLNFNMSVSSTK 188
+ R + GHT+ + + +DK + S D T +LWD + E KS+N + +
Sbjct: 733 KECR-NTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE 791
Query: 189 YIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAGGEDFKLYKY 248
P+ ++ VI S + A +VA L+
Sbjct: 792 D-PQEDMEVIVKCCSWSADGA------------------------RIMVAAKNKIFLWNT 826
Query: 249 FNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQT 291
+ + + +G+ +H V FS DG + + S+D T+RL +T
Sbjct: 827 DSRSKVADC-RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET 868
Score = 41.6 bits (96), Expect = 0.001
Identities = 50/258 (19%), Positives = 111/258 (43%), Gaps = 32/258 (12%)
Query: 54 TFWGHKGAVWGATLNATKA--ATAAADFTAKVWDAVLGDELMTLAHK------------- 98
T +GH +V + A+ +AD T K+WDA +E ++ K
Sbjct: 738 TMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDM 797
Query: 99 -YIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQIL 157
IVK + D ++ ++K+ +++ + +++ + GH S + ++ + L
Sbjct: 798 EVIVKCCSWSADGARIMVAAKNKIF-LWNTDS-RSKVADCRGHLSWVHGVMFSPDGSSFL 855
Query: 158 -SADDKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYG----LSIAFHSAVSL 212
S+DD+T RLW+ + + ++ V E E++V+ L + +
Sbjct: 856 TSSDDQTIRLWETKKVCKNSAVMLKQEVDVV--FQENEVMVLAVDHIRRLQLINGRTGQI 913
Query: 213 DPITSFEAPATINSASLHPEKEFLVAGGED--FKLYKYFNHGEEFESYKGYFGPIHCVRF 270
D +T A ++ L P +++ G E+ ++ + N+ F+S + + ++F
Sbjct: 914 DYLTE----AQVSCCCLSPHLQYIAFGDENGAIEILELVNN-RIFQSRFQHKKTVWHIQF 968
Query: 271 SRDGELYASGSEDGTLRL 288
+ D + S S+D +++
Sbjct: 969 TADEKTLISSSDDAEIQV 986
Score = 32.7 bits (73), Expect = 0.49
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 48 TGDWIGTFWGHKGAVWGATLN--ATKAATAAADFTAKVWDAVLGDELMTL-AHKYIVKTV 104
TG+ F H+G V ++ ATK ++ +AD TAK+W L L L H V+
Sbjct: 1031 TGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCS 1090
Query: 105 YFMQDSNYLLTKGQDKLLRMYDLN 128
F DS L T + +R+++++
Sbjct: 1091 AFSVDSTLLATGDDNGEIRIWNVS 1114
Score = 28.5 bits (62), Expect = 9.3
Identities = 11/30 (36%), Positives = 19/30 (63%)
Query: 259 KGYFGPIHCVRFSRDGELYASGSEDGTLRL 288
+G+ G + C FS D L A+G ++G +R+
Sbjct: 1081 RGHNGCVRCSAFSVDSTLLATGDDNGEIRI 1110
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 63.2 bits (152), Expect = 3e-10
Identities = 56/223 (25%), Positives = 99/223 (44%), Gaps = 31/223 (13%)
Query: 73 ATAAADFTAKVWDAVLGDELMTL-AHKYIVKTVYFMQDSNYLL--TKGQDKLLRMYDLNK 129
AT + D K+W+++ G+ + T H V +F S++LL T D L+++DLN+
Sbjct: 662 ATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQ 721
Query: 130 PKARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLWDHATMTEVKSLNFNMSVSSTK 188
+ R + GHT+ + + +DK + S D T +LWD + E KS+N + +
Sbjct: 722 KECR-NTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE 780
Query: 189 YIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAGGEDFKLYKY 248
P+ ++ VI S + A +VA L+
Sbjct: 781 D-PQEDMEVIVKCCSWSADGA------------------------RIMVAAKNKIFLWNT 815
Query: 249 FNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQT 291
+ + + +G+ +H V FS DG + + S+D T+RL +T
Sbjct: 816 DSRSKVADC-RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWET 857
Score = 41.6 bits (96), Expect = 0.001
Identities = 50/258 (19%), Positives = 111/258 (43%), Gaps = 32/258 (12%)
Query: 54 TFWGHKGAVWGATLNATKA--ATAAADFTAKVWDAVLGDELMTLAHK------------- 98
T +GH +V + A+ +AD T K+WDA +E ++ K
Sbjct: 727 TMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDM 786
Query: 99 -YIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQIL 157
IVK + D ++ ++K+ +++ + +++ + GH S + ++ + L
Sbjct: 787 EVIVKCCSWSADGARIMVAAKNKIF-LWNTDS-RSKVADCRGHLSWVHGVMFSPDGSSFL 844
Query: 158 -SADDKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYG----LSIAFHSAVSL 212
S+DD+T RLW+ + + ++ V E E++V+ L + +
Sbjct: 845 TSSDDQTIRLWETKKVCKNSAVMLKQEVDVV--FQENEVMVLAVDHIRRLQLINGRTGQI 902
Query: 213 DPITSFEAPATINSASLHPEKEFLVAGGED--FKLYKYFNHGEEFESYKGYFGPIHCVRF 270
D +T A ++ L P +++ G E+ ++ + N+ F+S + + ++F
Sbjct: 903 DYLTE----AQVSCCCLSPHLQYIAFGDENGAIEILELVNN-RIFQSRFQHKKTVWHIQF 957
Query: 271 SRDGELYASGSEDGTLRL 288
+ D + S S+D +++
Sbjct: 958 TADEKTLISSSDDAEIQV 975
Score = 32.7 bits (73), Expect = 0.49
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 48 TGDWIGTFWGHKGAVWGATLN--ATKAATAAADFTAKVWDAVLGDELMTL-AHKYIVKTV 104
TG+ F H+G V ++ ATK ++ +AD TAK+W L L L H V+
Sbjct: 1020 TGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCS 1079
Query: 105 YFMQDSNYLLTKGQDKLLRMYDLN 128
F DS L T + +R+++++
Sbjct: 1080 AFSVDSTLLATGDDNGEIRIWNVS 1103
Score = 28.5 bits (62), Expect = 9.3
Identities = 11/30 (36%), Positives = 19/30 (63%)
Query: 259 KGYFGPIHCVRFSRDGELYASGSEDGTLRL 288
+G+ G + C FS D L A+G ++G +R+
Sbjct: 1070 RGHNGCVRCSAFSVDSTLLATGDDNGEIRI 1099
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 5/152 (3%)
Query: 29 GYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKGAVWGATLNAT--KAATAAADFTAKVWDA 86
G L Y+DG + +G+ TF GHK A+ + + A+ + D VWD
Sbjct: 77 GLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDV 136
Query: 87 VLGDELMTL-AHKYIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIK 145
+ L L HK + F+++ N L+T G+D +++ +DL+ K + GH + +
Sbjct: 137 INESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCF-KTMVGHRTEVW 195
Query: 146 KGLWCSEDKQILS-ADDKTARLWDHATMTEVK 176
+ SE+K++++ A D R+WD A + E++
Sbjct: 196 GLVLLSEEKRLITGASDSELRVWDIAYLQEIE 227
Score = 46.6 bits (109), Expect = 3e-05
Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 13/130 (10%)
Query: 47 DTGDWIGTFWGHKGAVWGATLNATKA--ATAAADFTAKVWDAVLGDELMTL-AHKYIVKT 103
DT + + +GHK V ++ A AT +AD K+W GD +L AH V
Sbjct: 579 DTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMY 638
Query: 104 VYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWC-----SEDKQILS 158
+ F+ S+ T G+D ++ +D +K + + + GH + +WC S D + S
Sbjct: 639 LQFVPKSHLFFTAGKDHKIKQWDADKFE-HIQTLEGH----HQEIWCLAVSPSGDYVVSS 693
Query: 159 ADDKTARLWD 168
+ DK+ RLW+
Sbjct: 694 SHDKSLRLWE 703
Score = 42.7 bits (99), Expect = 5e-04
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 20/191 (10%)
Query: 118 QDKLLRMYDLNKPKARPKE-------ISGHTSGIKKGLWCSEDKQILSADDKTARLWDHA 170
Q+ L+ +Y LN P+ I GH S ++ + S++ +LSA + ++W+ +
Sbjct: 385 QNNLVELYSLNPSLPTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRS 444
Query: 171 TMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEA-PATINSASL 229
T+ ++++ ++ S + ++++ T + + S + + + +A + S SL
Sbjct: 445 TLQCIRTMTCEYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSL 504
Query: 230 HPEKEFLVAGGE-------DFKLYKYFNHGEEFESYK-----GYFGPIHCVRFSRDGELY 277
P++ V GG DF+L K N ++ S K + CV +S + +L
Sbjct: 505 SPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLL 564
Query: 278 ASGSEDGTLRL 288
A D T+++
Sbjct: 565 AVSLLDCTVKI 575
Score = 32.3 bits (72), Expect = 0.64
Identities = 59/296 (19%), Positives = 106/296 (35%), Gaps = 65/296 (21%)
Query: 54 TFWGHKGAVWGATLNATKAA--TAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSN 111
T GH+ V + ++ A +AAAD + K+W+ + T+ +Y + + + D
Sbjct: 410 TIGGHRSDVRTLSFSSDNIAVLSAAAD-SIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQ 468
Query: 112 YLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQ--ILSADDKTARLWDH 169
++ KL ++YDL + I H G + S D++ + DK+ + WD
Sbjct: 469 VVIGTKTGKL-QLYDLASGNLL-ETIDAH-DGALWSMSLSPDQRGFVTGGADKSVKFWDF 525
Query: 170 ATMTEVKSLNFNMSVSSTK------------YIPEGEILVITY----------------- 200
+ + S +SV T+ Y P ++L ++
Sbjct: 526 ELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFL 585
Query: 201 -----------------GLSIAFHSAVSLDPITSFEAPATINSASLH----------PEK 233
G IA SA I + S H P+
Sbjct: 586 SLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKS 645
Query: 234 EFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRL 288
G+D K+ ++ + E ++ +G+ I C+ S G+ S S D +LRL
Sbjct: 646 HLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRL 701
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 37 KDGKPMLRQGDTGDWIGTFWGHKGAVWGATLNATKA--ATAAADFTAKVWD-AVLGDELM 93
K GK L +G+ + T H GA+W +L+ + T AD + K WD ++ DE
Sbjct: 474 KTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENS 533
Query: 94 TLAHKYIVKTVYFMQDSNYL 113
T + +T D + L
Sbjct: 534 TQKRLSVKQTRTLQLDEDVL 553
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 60.1 bits (144), Expect = 3e-09
Identities = 63/276 (22%), Positives = 115/276 (41%), Gaps = 13/276 (4%)
Query: 23 SGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKGAVWGATLNATKA--ATAAADFT 80
S + G L + +DG + +G + GH G V + A+A+ D T
Sbjct: 27 SAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCT 86
Query: 81 AKVWDAVLGDELMTL-AHKYIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISG 139
++WD L L H+ V+TV F DS L + G DK + ++D+ + + + G
Sbjct: 87 VRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQML-RLLVG 145
Query: 140 HTSGIKKGLWCSEDKQILSAD-DKTARLWDHATMTEVKSLN----FNMSVSSTKYIPEGE 194
H I+ + + + D T +WD +T S + ++S Y G
Sbjct: 146 HRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASGL 205
Query: 195 ILVITYGLSIAFHSAVSLDPITSFEAPAT-INSASLHPEKEFLVAGGEDFKLYKYF--NH 251
+ ++ +I + + + T + S + P++ +L + G ++ K + N
Sbjct: 206 LASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYS-RMVKVWDCNT 264
Query: 252 GEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLR 287
G+ E+ KG H F+ DG++ SG+ D T R
Sbjct: 265 GKCLETLKGVLDVAHTCAFTPDGKILVSGAADQTRR 300
Score = 45.4 bits (106), Expect = 7e-05
Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Query: 224 INSASLHPEKEFLVAGGEDFKLYKYFNH-GEEFESYKGYFGPIHCVRFSRDGELYASGSE 282
+NS++ P+ + L+ G ED +Y + G+ G+ GP+ RFS DG L+AS S
Sbjct: 24 VNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASC 83
Query: 283 DGTLRL 288
D T+RL
Sbjct: 84 DCTVRL 89
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 59.7 bits (143), Expect = 4e-09
Identities = 65/244 (26%), Positives = 118/244 (48%), Gaps = 17/244 (6%)
Query: 54 TFWGHKGAVWGATL--NATKAATAAADFTAKVWDAVLGDELMTLA-HKYIVKTVYFMQDS 110
T GH AV N A+++AD K+W A G T++ HK + V + DS
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 111 NYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLWDH 169
N L++ DK L+++D++ K K + GH++ + + + I+S D++ R+WD
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCL-KTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 158
Query: 170 ATMTEVKSLNFNMS-VSSTKYIPEGEILVITY--GLSIAFHSAVS--LDPITSFEAPATI 224
T +K+L + VS+ + +G ++V + GL + +A L + + P +
Sbjct: 159 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP-PV 217
Query: 225 NSASLHPEKEFLVAGGED--FKLYKYFNHGEEFESYKGYFGPIHCV--RFS-RDGELYAS 279
+ P ++++A D KL+ Y + G+ ++Y G+ +C+ FS G+ S
Sbjct: 218 SFVKFSPNGKYILAATLDNTLKLWDY-SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 276
Query: 280 GSED 283
GSED
Sbjct: 277 GSED 280
Score = 58.5 bits (140), Expect = 8e-09
Identities = 54/205 (26%), Positives = 86/205 (41%), Gaps = 43/205 (20%)
Query: 94 TLA-HKYIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSE 152
TLA H V +V F + +L + DKL++++ K K ISGH GI W S+
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFE-KTISGHKLGISDVAWSSD 98
Query: 153 DKQILSA-DDKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVS 211
++SA DDKT ++WD VSS K + ++ HS
Sbjct: 99 SNLLVSASDDKTLKIWD---------------VSSGKCLK-----------TLKGHSNY- 131
Query: 212 LDPITSFEAPATINSASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRF 270
+ + +P+ +V+G D + + G+ ++ + P+ V F
Sbjct: 132 ------------VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179
Query: 271 SRDGELYASGSEDGTLRLGQTVVGK 295
+RDG L S S DG R+ T G+
Sbjct: 180 NRDGSLIVSSSYDGLCRIWDTASGQ 204
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 59.7 bits (143), Expect = 4e-09
Identities = 65/244 (26%), Positives = 118/244 (48%), Gaps = 17/244 (6%)
Query: 54 TFWGHKGAVWGATL--NATKAATAAADFTAKVWDAVLGDELMTLA-HKYIVKTVYFMQDS 110
T GH AV N A+++AD K+W A G T++ HK + V + DS
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 111 NYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLWDH 169
N L++ DK L+++D++ K K + GH++ + + + I+S D++ R+WD
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCL-KTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 158
Query: 170 ATMTEVKSLNFNMS-VSSTKYIPEGEILVITY--GLSIAFHSAVS--LDPITSFEAPATI 224
T +K+L + VS+ + +G ++V + GL + +A L + + P +
Sbjct: 159 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP-PV 217
Query: 225 NSASLHPEKEFLVAGGED--FKLYKYFNHGEEFESYKGYFGPIHCV--RFS-RDGELYAS 279
+ P ++++A D KL+ Y + G+ ++Y G+ +C+ FS G+ S
Sbjct: 218 SFVKFSPNGKYILAATLDNTLKLWDY-SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 276
Query: 280 GSED 283
GSED
Sbjct: 277 GSED 280
Score = 58.5 bits (140), Expect = 8e-09
Identities = 54/205 (26%), Positives = 86/205 (41%), Gaps = 43/205 (20%)
Query: 94 TLA-HKYIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSE 152
TLA H V +V F + +L + DKL++++ K K ISGH GI W S+
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFE-KTISGHKLGISDVAWSSD 98
Query: 153 DKQILSA-DDKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVS 211
++SA DDKT ++WD VSS K + ++ HS
Sbjct: 99 SNLLVSASDDKTLKIWD---------------VSSGKCLK-----------TLKGHSNY- 131
Query: 212 LDPITSFEAPATINSASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRF 270
+ + +P+ +V+G D + + G+ ++ + P+ V F
Sbjct: 132 ------------VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179
Query: 271 SRDGELYASGSEDGTLRLGQTVVGK 295
+RDG L S S DG R+ T G+
Sbjct: 180 NRDGSLIVSSSYDGLCRIWDTASGQ 204
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 59.3 bits (142), Expect = 5e-09
Identities = 63/258 (24%), Positives = 108/258 (41%), Gaps = 29/258 (11%)
Query: 9 TYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKGAV---WGA 65
T GH+ +++L ++ T G L SA D + +TG+ + GH V + A
Sbjct: 104 TLKGHSGAVMELHYN---TDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPA 160
Query: 66 TLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTKGQDKLLRMY 125
T + D T K+WD + T + Y V V F S+ +++ G D ++++
Sbjct: 161 RRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVW 220
Query: 126 DLNKPKARPKEISGHTSGIKKGLWCSEDKQILS-ADDKTARLWDHATMTEVKSL------ 178
DL + K + GH + SE +LS A D T R+WD +
Sbjct: 221 DLRQNKLT-YTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQG 279
Query: 179 ---NFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITS----FEAPA---TINSAS 228
NF ++ + P+G I G + F V + TS ++ P +IN +
Sbjct: 280 NVHNFEKNLLRCSWSPDGS--KIAAGSADRF---VYVWDTTSRRILYKLPGHAGSINEVA 334
Query: 229 LHPEKEFLVAGGEDFKLY 246
HP++ +++ D +LY
Sbjct: 335 FHPDEPIIISASSDKRLY 352
Score = 30.4 bits (67), Expect = 2.4
Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 230 HPEKEFLVAGGED--FKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLR 287
HP L + G D L+ + + + + KG+ G + + ++ DG + S S D T+
Sbjct: 75 HPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVA 134
Query: 288 LGQTVVGK 295
+ + G+
Sbjct: 135 VWDSETGE 142
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 58.9 bits (141), Expect = 6e-09
Identities = 59/251 (23%), Positives = 100/251 (39%), Gaps = 47/251 (18%)
Query: 48 TGDWIGTFWGHKGAVWGATLNATK--AATAAADFTAKVWDAVLGDELMTL-AHKYIVKTV 104
T + +GH G V+GA+ + + +++ D T ++W L+ H Y V
Sbjct: 532 TASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDT 591
Query: 105 YFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEI-SGHTSGIKKGLWCSEDKQILSAD-DK 162
F Y ++ G D++ R++ + +P I +GH + + + + + D+
Sbjct: 592 QFSPYGYYFVSGGHDRVARLWATDH--YQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 649
Query: 163 TARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPA 222
T RLWD + G + I T + P
Sbjct: 650 TVRLWD---------------------VLNGNCVRI----------------FTGHKGP- 671
Query: 223 TINSASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDGELYASGS 281
I+S + P FL G D ++ + HG KG+ + +RFSRDGE+ ASGS
Sbjct: 672 -IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGS 730
Query: 282 EDGTLRLGQTV 292
D T+RL +
Sbjct: 731 MDNTVRLWDAI 741
Score = 38.9 bits (89), Expect = 0.007
Identities = 47/211 (22%), Positives = 81/211 (38%), Gaps = 26/211 (12%)
Query: 94 TLAHKYIVKTVYFMQDSNYLLTKG-QDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSE 152
T + Y T + D + L+ G D +R++ + K R + + S I K
Sbjct: 465 TFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDK------ 518
Query: 153 DKQILSADDKTARLWDHATMTEVKSL-NFNMSVSSTKYIPEGEILVITYGLSIAFHSAVS 211
+DD R+ D T +E+K L + V + P+ L LS + V
Sbjct: 519 -----ESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYL-----LSSSEDGTVR 568
Query: 212 LDPITSFEAPA-------TINSASLHPEKEFLVAGGEDFKLYKYF-NHGEEFESYKGYFG 263
L + +F + P + V+GG D + +H + + G+
Sbjct: 569 LWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLA 628
Query: 264 PIHCVRFSRDGELYASGSEDGTLRLGQTVVG 294
++C RF + A+GS D T+RL + G
Sbjct: 629 DVNCTRFHPNSNYVATGSADRTVRLWDVLNG 659
Score = 33.5 bits (75), Expect = 0.29
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 5/80 (6%)
Query: 10 YFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKGAVWGA--TL 67
+ GH P+ L FS G FL + DG+ +L G +G GH V +
Sbjct: 665 FTGHKGPIHSLTFS---PNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSR 721
Query: 68 NATKAATAAADFTAKVWDAV 87
+ A+ + D T ++WDA+
Sbjct: 722 DGEILASGSMDNTVRLWDAI 741
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 58.5 bits (140), Expect = 8e-09
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 8/163 (4%)
Query: 10 YFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKGAVWGATL-- 67
Y GH +P+ DL I+ Y + S D L D + + GH V
Sbjct: 380 YQGHAYPVWDL---DISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHP 436
Query: 68 NATKAATAAADFTAKVWDAVLGDEL-MTLAHKYIVKTVYFMQDSNYLLTKGQDKLLRMYD 126
N+ AT + D T ++W A G+ + + H+ V ++ F + YL + G+D+ L+++D
Sbjct: 437 NSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWD 496
Query: 127 LNKPKARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLWD 168
L KE+ GHT I + + I SA D + R+WD
Sbjct: 497 LASGTLY-KELRGHTDNITSLTFSPDSGLIASASMDNSVRVWD 538
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/175 (22%), Positives = 67/175 (38%), Gaps = 19/175 (10%)
Query: 135 KEISGHTSGIKKGLWCSEDKQILS-ADDKTARLWDHATMTEVKSLNFNMSVSSTKYIPEG 193
K + GH + + ++ +LS ++D + R WD + T N + P
Sbjct: 336 KILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFT-------NTVLYQGHAYPVW 388
Query: 194 EILVITYGLSIAFHSAVSLDPITSFEAP----------ATINSASLHPEKEFLVAGGEDF 243
++ + Y L A S + SF+ A ++ HP +L G D
Sbjct: 389 DLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDK 448
Query: 244 KLYKYF-NHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRLGQTVVGKTY 297
+ + G + G+ GP+ + FS +G+ AS ED L+L G Y
Sbjct: 449 TVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLY 503
Score = 35.4 bits (80), Expect = 0.076
Identities = 44/205 (21%), Positives = 80/205 (39%), Gaps = 14/205 (6%)
Query: 100 IVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSA 159
++ T DS L + ++++ L K + + S I L C IL
Sbjct: 270 LLNTAEISPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIH--LACD----ILEE 323
Query: 160 DDKTARLWDHATMTEVKSLNFNMS-VSSTKYIPEGE-ILVITYGLSIAFHSAVSLDPITS 217
+D D TE+K L + V ST+++ + +L + +SI + S
Sbjct: 324 EDDE----DDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVL 379
Query: 218 FEAPA-TINSASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDGE 275
++ A + + P + +G D + F+ Y G+ + CV+F +
Sbjct: 380 YQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSN 439
Query: 276 LYASGSEDGTLRLGQTVVGKTYGLW 300
A+GS D T+RL G + L+
Sbjct: 440 YLATGSTDKTVRLWSAQQGNSVRLF 464
>gi|153791298 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 57.0 bits (136), Expect = 2e-08
Identities = 53/207 (25%), Positives = 90/207 (43%), Gaps = 10/207 (4%)
Query: 101 VKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSAD 160
V+ V F D NY LT G DK L++++ + + SGH + ++ + S
Sbjct: 28 VRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLL-RTYSGHGYEVLDAAGSFDNSSLCSGG 86
Query: 161 -DKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHS----AVSLDPI 215
DK LWD A+ V+ + +T E ++++ + + + +P+
Sbjct: 87 GDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPV 146
Query: 216 TSFEAPATINSASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDG 274
+ + A +S+ ++AG D ++ +Y G+ F Y G PI C FSRDG
Sbjct: 147 QTLDE-ARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVG--SPITCTCFSRDG 203
Query: 275 ELYASGSEDGTLRLGQTVVGKTYGLWK 301
+ S D TLRL G+ G +K
Sbjct: 204 QCTLVSSLDSTLRLLDKDTGELLGEYK 230
>gi|14150114 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 57.0 bits (136), Expect = 2e-08
Identities = 53/207 (25%), Positives = 90/207 (43%), Gaps = 10/207 (4%)
Query: 101 VKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSAD 160
V+ V F D NY LT G DK L++++ + + SGH + ++ + S
Sbjct: 28 VRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLL-RTYSGHGYEVLDAAGSFDNSSLCSGG 86
Query: 161 -DKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHS----AVSLDPI 215
DK LWD A+ V+ + +T E ++++ + + + +P+
Sbjct: 87 GDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPV 146
Query: 216 TSFEAPATINSASLHPEKEFLVAGGEDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDG 274
+ + A +S+ ++AG D ++ +Y G+ F Y G PI C FSRDG
Sbjct: 147 QTLDE-ARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLFSDYVG--SPITCTCFSRDG 203
Query: 275 ELYASGSEDGTLRLGQTVVGKTYGLWK 301
+ S D TLRL G+ G +K
Sbjct: 204 QCTLVSSLDSTLRLLDKDTGELLGEYK 230
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 55.1 bits (131), Expect = 9e-08
Identities = 53/199 (26%), Positives = 91/199 (45%), Gaps = 28/199 (14%)
Query: 5 QTLLTYFGHTWPMVDLAFSGITTYGYFLTSAYKDGKPMLRQGDTGDWIGTFWGHKGAVWG 64
+ + T GH + +A I G + SA +D + + TG + TF GH+ V
Sbjct: 183 ECIRTMHGHDHNVSSVA---IMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRM 239
Query: 65 ATLN--ATKAATAAADFTAKVWDAVLGDELMTLA-HKYIVKTVYFMQDSNY--------- 112
N T A+ + D T +VW + L H+++V+ + + +S+Y
Sbjct: 240 VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGS 299
Query: 113 -----------LLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILS-AD 160
LL+ +DK ++M+D++ + GH + ++ L+ S K ILS AD
Sbjct: 300 ETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCL-MTLVGHDNWVRGVLFHSGGKFILSCAD 358
Query: 161 DKTARLWDHATMTEVKSLN 179
DKT R+WD+ +K+LN
Sbjct: 359 DKTLRVWDYKNKRCMKTLN 377
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/152 (24%), Positives = 63/152 (41%), Gaps = 11/152 (7%)
Query: 36 YKDGKPMLRQGDTGDWIG------TFWGHKGAVWGATLNATKAA--TAAADFTAKVWDAV 87
+ G P+ ++ D +WI GH+ V + + +A+ D T KVWD
Sbjct: 79 FTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYE 138
Query: 88 LGDELMTL-AHKYIVKTVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKK 146
GD TL H V+ + F L + D ++++D + + + GH +
Sbjct: 139 TGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFEC-IRTMHGHDHNVSS 197
Query: 147 GLWCSEDKQILSAD-DKTARLWDHATMTEVKS 177
I+SA DKT ++W+ T VK+
Sbjct: 198 VAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/169 (24%), Positives = 78/169 (46%), Gaps = 18/169 (10%)
Query: 133 RPKE---ISGHTSGIKKGLWCSEDKQILSA-DDKTARLWDHATMTEVKSLNFNM-SVSST 187
RP E +SGH S + + ++ ++SA +D T ++WD+ T ++L + SV
Sbjct: 97 RPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDI 156
Query: 188 KYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPAT-------INSASLHPEKEFLVAGG 240
+ G++L S + + L FE T ++S ++ P + +V+
Sbjct: 157 SFDHSGKLLA-----SCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSAS 211
Query: 241 EDFKLYKY-FNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTLRL 288
D + + G +++ G+ + VR ++DG L AS S D T+R+
Sbjct: 212 RDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRV 260
>gi|148536855 coatomer protein complex, subunit alpha isoform 1
[Homo sapiens]
Length = 1233
Score = 54.3 bits (129), Expect = 2e-07
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 21/245 (8%)
Query: 52 IGTFWGHKGAVWGATLNATKA--ATAAADFTAKVWDAVLGDELMTL-AHKYIVKTVYFMQ 108
I F H G V G + + + D+ KVW+ L L TL H ++T +F
Sbjct: 44 IDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHH 103
Query: 109 DSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLW 167
+ ++L+ D+ +R+++ + ++GH + + + ++SA D+T R+W
Sbjct: 104 EYPWILSASDDQTIRVWNWQS-RTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVW 162
Query: 168 DHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSA 227
D + + + N+S + + G V +G + AV + + +N A
Sbjct: 163 DISGLRKK-----NLSPGAVESDVRGITGVDLFGTT----DAVVKHVLEGHDRG--VNWA 211
Query: 228 SLHPEKEFLVAGGEDFKLYKYFNHGE----EFESYKGYFGPIHCVRFSRDGELYASGSED 283
+ HP +V+G +D ++ K + E E ++ +G++ + C F EL S SED
Sbjct: 212 AFHPTMPLIVSGADDRQV-KIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSED 270
Query: 284 GTLRL 288
++R+
Sbjct: 271 KSIRV 275
Score = 29.3 bits (64), Expect = 5.4
Identities = 16/67 (23%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Query: 113 LLTKGQDKLLRMYDLNKPKARPKEIS-GHTSGIKKGLWCSEDKQILS-ADDKTARLWDHA 170
+++ D+ ++++ +N+ KA + GH + + ++ + ILS ++DK+ R+WD +
Sbjct: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
Query: 171 TMTEVKS 177
T V++
Sbjct: 280 KRTGVQT 286
>gi|148536853 coatomer protein complex, subunit alpha isoform 2
[Homo sapiens]
Length = 1224
Score = 54.3 bits (129), Expect = 2e-07
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 21/245 (8%)
Query: 52 IGTFWGHKGAVWGATLNATKA--ATAAADFTAKVWDAVLGDELMTL-AHKYIVKTVYFMQ 108
I F H G V G + + + D+ KVW+ L L TL H ++T +F
Sbjct: 44 IDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHH 103
Query: 109 DSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLW 167
+ ++L+ D+ +R+++ + ++GH + + + ++SA D+T R+W
Sbjct: 104 EYPWILSASDDQTIRVWNWQS-RTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVW 162
Query: 168 DHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSA 227
D + + + N+S + + G V +G + AV + + +N A
Sbjct: 163 DISGLRKK-----NLSPGAVESDVRGITGVDLFGTT----DAVVKHVLEGHDRG--VNWA 211
Query: 228 SLHPEKEFLVAGGEDFKLYKYFNHGE----EFESYKGYFGPIHCVRFSRDGELYASGSED 283
+ HP +V+G +D ++ K + E E ++ +G++ + C F EL S SED
Sbjct: 212 AFHPTMPLIVSGADDRQV-KIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSED 270
Query: 284 GTLRL 288
++R+
Sbjct: 271 KSIRV 275
Score = 29.3 bits (64), Expect = 5.4
Identities = 16/67 (23%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Query: 113 LLTKGQDKLLRMYDLNKPKARPKEIS-GHTSGIKKGLWCSEDKQILS-ADDKTARLWDHA 170
+++ D+ ++++ +N+ KA + GH + + ++ + ILS ++DK+ R+WD +
Sbjct: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
Query: 171 TMTEVKS 177
T V++
Sbjct: 280 KRTGVQT 286
>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
Length = 2627
Score = 52.8 bits (125), Expect = 5e-07
Identities = 63/259 (24%), Positives = 100/259 (38%), Gaps = 37/259 (14%)
Query: 62 VWGATLNATKAATAAADFTAKVW------------DAVLGDELMTLAHKYIVKTVYFMQD 109
V G + A+A+ DFT ++W D G EL H+ V F D
Sbjct: 2015 VLGLATSQELLASASEDFTVQLWPRQLLTRPHKAEDFPCGTELR--GHEGPVSCCSFSTD 2072
Query: 110 SNYLLTKGQDKLLRMYDLNKPKARPKEISG----HTSGIKKGLWCSEDKQILSADDKTAR 165
L T G+D+ L +D+ PK P I H + W ++ I + D +
Sbjct: 2073 GGSLATGGRDRSLLCWDVRTPKT-PVLIHSFPACHRDWVTGCAWTKDNLLISCSSDGSVG 2131
Query: 166 LWDHATMTEV-KSLNFNMSVSSTKYIPEGEILVITYG-LSIAFHSAVSLDPITSFEAPAT 223
LWD + + + L +VS+ + E + V G L + H V L I + P +
Sbjct: 2132 LWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWDHQGVELTSIPAHSGPIS 2191
Query: 224 INSASLHPEKEFLVAG--GEDFKLYKYFNHGE----------EFESYKGYFGPIHCVRFS 271
+A++ P AG G + + G + + G+ GP+ S
Sbjct: 2192 HCAAAMEPR----AAGQPGSELLVVTVGLDGATRLWHPLLVCQTHTLLGHSGPVRAAAVS 2247
Query: 272 RDGELYASGSEDGTLRLGQ 290
L + SEDG++RL Q
Sbjct: 2248 ETSGLMLTASEDGSVRLWQ 2266
Score = 34.7 bits (78), Expect = 0.13
Identities = 52/233 (22%), Positives = 93/233 (39%), Gaps = 24/233 (10%)
Query: 73 ATAAADFTAKVWDAVLGDELMTL-AHKYIVKTVYFMQDSNYLLTKGQDKLLRMYD--LNK 129
A D ++W G L AH V F+ LLT G+D ++++ L +
Sbjct: 1858 AVGRLDSMVELWAWREGARLAAFPAHHGFVAAALFLHAGCQLLTAGEDGKVQVWSGSLGR 1917
Query: 130 PKARPKEISGHTSGIKKGLWCSEDKQILSADDKTARLWDHATMTE-VKSLNFNMSVS--- 185
P+ +S + + L D+ + R++ ++ ++ + +++VS
Sbjct: 1918 PRGHLGSLS-LSPALSVALSPDGDRVAVGYRADGIRIYKISSGSQGAQGQALDVAVSALA 1976
Query: 186 --STKYIPEGEILVITYGLSIAFHSAVSLDPITSFEAPATINSASLHPEKEFLVAGGEDF 243
S K + G G ++ S SL ++ F+ P L +E L + EDF
Sbjct: 1977 WLSPKVLVSGAEDGSLQGWALKECSLQSLWLLSRFQKPVL----GLATSQELLASASEDF 2032
Query: 244 -------KLYKYFNHGEEFE---SYKGYFGPIHCVRFSRDGELYASGSEDGTL 286
+L + E+F +G+ GP+ C FS DG A+G D +L
Sbjct: 2033 TVQLWPRQLLTRPHKAEDFPCGTELRGHEGPVSCCSFSTDGGSLATGGRDRSL 2085
Score = 33.5 bits (75), Expect = 0.29
Identities = 18/54 (33%), Positives = 24/54 (44%)
Query: 32 LTSAYKDGKPMLRQGDTGDWIGTFWGHKGAVWGATLNATKAATAAADFTAKVWD 85
L S DG L ++G +G F GH+ AV + + D T KVWD
Sbjct: 2121 LISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWD 2174
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 52.0 bits (123), Expect = 8e-07
Identities = 52/205 (25%), Positives = 84/205 (40%), Gaps = 45/205 (21%)
Query: 95 LAHKYIVKTVYFMQDSNYLL-TKGQDKLLRMYDLNKPKARPKEISGHTSGIKK-GLWCSE 152
+AH V ++ + S LL T G D + ++ +NKP ++GHTS ++ L E
Sbjct: 17 VAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCI-MSLTGHTSPVESVRLNTPE 75
Query: 153 DKQILSADDKTARLWDHATMTEVKSLNFNMSVSSTKYIPEGEILVITYGLSIAFHSAVSL 212
+ + + + R+WD + +IL G
Sbjct: 76 ELIVAGSQSGSIRVWD---------------------LEAAKILRTLMGHK--------- 105
Query: 213 DPITSFEAPATINSASLHPEKEFLVAGGED--FKLYKYFNHGEEFESYKGYFGPIHCVRF 270
A I S HP EF+ +G +D KL+ G F Y+G+ + C+RF
Sbjct: 106 ---------ANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFR-YRGHSQAVRCLRF 155
Query: 271 SRDGELYASGSEDGTLRLGQTVVGK 295
S DG+ AS ++D T++L GK
Sbjct: 156 SPDGKWLASAADDHTVKLWDLTAGK 180
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/233 (22%), Positives = 95/233 (40%), Gaps = 20/233 (8%)
Query: 73 ATAAADFTAKVWDAVLGDELMTLA-HKYIVKTVYFMQDSNYLLTKG-QDKLLRMYDLNKP 130
AT + K+WD G L+ L H +V+ + F D + +L +DK LR++DL
Sbjct: 144 ATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDD 203
Query: 131 KARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLWDHATMTEVKSL-NFNMSVSSTK 188
K + GH + + + + + S K LW+ T ++ L + V +
Sbjct: 204 GNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 189 YIPEGEIL-VITYGLSIAFHSAVSLDPITSFE---APAT-----------INSASLHPEK 233
+ P+G +L +Y + + D + F P T + S S +
Sbjct: 264 FSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHD- 322
Query: 234 EFLVAGGEDFKLYKYFNHGEEFESYKGYFGPIHCVRFSRDGELYASGSEDGTL 286
VA D K+ +++ E++ C FS DG + A+G+ DG++
Sbjct: 323 GLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSV 375
Score = 39.7 bits (91), Expect = 0.004
Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 22/139 (15%)
Query: 73 ATAAADFTAKVWDAVLGDELMTLAHKY--------------IVKTVYFMQDSNYLLTKGQ 118
ATA+ D +WD GD LM H + V++V F D ++ +
Sbjct: 272 ATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLAD 331
Query: 119 DKLLRMYDLNKPKARPKEISGHTSGIKKGLWC--SEDKQILSADDKTARLWDHATMTEVK 176
DK++R + ++ ++ + + GL C S D +L+A ++ AT +V
Sbjct: 332 DKMVRFWRID------EDYPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSVYFWATPRQVP 385
Query: 177 SLNFNMSVSSTKYIPEGEI 195
SL +S + +P E+
Sbjct: 386 SLQHLCRMSIRRVMPTQEV 404
>gi|4502477 beta-transducin repeat containing protein isoform 2
[Homo sapiens]
Length = 569
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/126 (26%), Positives = 66/126 (52%), Gaps = 6/126 (4%)
Query: 57 GHKGAVWGATLNATKAATAAADFTAKVWDAVLGDELMTLAHKYIVKTVYFMQDSNYLLTK 116
GH G+V + T ++D T +VWD G+ L TL H + ++ ++ ++T
Sbjct: 305 GHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIH-HCEAVLHLRFNNGMMVTC 363
Query: 117 GQDKLLRMYDLNKPK--ARPKEISGHTSGIKKGLWCSEDKQILSAD-DKTARLWDHATMT 173
+D+ + ++D+ P + + GH + + + +DK I+SA D+T ++W+ +T
Sbjct: 364 SKDRSIAVWDMASPTDITLRRVLVGHRAAV--NVVDFDDKYIVSASGDRTIKVWNTSTCE 421
Query: 174 EVKSLN 179
V++LN
Sbjct: 422 FVRTLN 427
Score = 42.0 bits (97), Expect = 8e-04
Identities = 32/129 (24%), Positives = 63/129 (48%), Gaps = 14/129 (10%)
Query: 47 DTGDWIGTFWGHKGAVWGATLNATKAATAAADFTAKVWDAVLGDEL----MTLAHKYIVK 102
+TG+ + T H AV N T + D + VWD ++ + + H+ V
Sbjct: 335 NTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVN 394
Query: 103 TVYFMQDSNYLLTKGQDKLLRMYDLNKPKARPKEISGHTSGIKKGLWCSE--DKQILS-A 159
V F D Y+++ D+ +++++ + + + ++GH K+G+ C + D+ ++S +
Sbjct: 395 VVDF--DDKYIVSASGDRTIKVWNTSTCEF-VRTLNGH----KRGIACLQYRDRLVVSGS 447
Query: 160 DDKTARLWD 168
D T RLWD
Sbjct: 448 SDNTIRLWD 456
Score = 34.7 bits (78), Expect = 0.13
Identities = 34/146 (23%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 31 FLTSAYKDGKPMLRQGDTGDWIGTFWGHKGAVWGATLNATKAATAAADFTAKVWDAVLGD 90
++ SA D + T +++ T GHK + + ++D T ++WD G
Sbjct: 402 YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGA 461
Query: 91 ELMTL-AHKYIVKTVYFMQDSNYLLTKGQDKLLRMYDL---NKPKARPKEISGHT----S 142
L L H+ +V+ + F D+ +++ D ++++DL P+A + T S
Sbjct: 462 CLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHS 519
Query: 143 GIKKGLWCSEDKQILSADDKTARLWD 168
G L E + + S+ D T +WD
Sbjct: 520 GRVFRLQFDEFQIVSSSHDDTILIWD 545
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,360,510
Number of Sequences: 37866
Number of extensions: 601586
Number of successful extensions: 2370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 1813
Number of HSP's gapped (non-prelim): 512
length of query: 347
length of database: 18,247,518
effective HSP length: 103
effective length of query: 244
effective length of database: 14,347,320
effective search space: 3500746080
effective search space used: 3500746080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.