Guide to the Human Genome
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Search of human proteins with 239752263

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239752263 PREDICTED: hypothetical protein XP_002348185 [Homo
sapiens]
         (220 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239752263 PREDICTED: hypothetical protein XP_002348185 [Homo ...   459   e-130
gi|239746776 PREDICTED: hypothetical protein XP_002343846 [Homo ...   294   5e-80
gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo ...   287   6e-78
gi|239757968 PREDICTED: hypothetical protein [Homo sapiens]           162   3e-40
gi|239747023 PREDICTED: hypothetical protein XP_002343907 [Homo ...   162   3e-40
gi|239747021 PREDICTED: hypothetical protein XP_002343906 [Homo ...   162   3e-40
gi|150170670 piccolo isoform 2 [Homo sapiens]                          66   2e-11
gi|150378539 piccolo isoform 1 [Homo sapiens]                          66   2e-11
gi|146134388 YLP motif containing 1 [Homo sapiens]                     64   1e-10
gi|27436925 synoviolin 1 isoform a [Homo sapiens]                      59   2e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   3e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    58   6e-09
gi|27436927 synoviolin 1 isoform b [Homo sapiens]                      58   7e-09
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 56   3e-08
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              56   3e-08
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    55   4e-08
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 55   5e-08
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     55   5e-08
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     54   1e-07
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     54   1e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    53   2e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    53   2e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     53   2e-07
gi|157168329 formin 1 [Homo sapiens]                                   52   3e-07
gi|15529996 son of sevenless homolog 1 [Homo sapiens]                  52   3e-07
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    52   3e-07
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    52   4e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    52   5e-07
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    51   7e-07
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    51   7e-07

>gi|239752263 PREDICTED: hypothetical protein XP_002348185 [Homo
           sapiens]
          Length = 220

 Score =  459 bits (1182), Expect = e-130
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MLISVSQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNAL 60
           MLISVSQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNAL
Sbjct: 1   MLISVSQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNAL 60

Query: 61  FSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSP 120
           FSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSP
Sbjct: 61  FSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSP 120

Query: 121 DSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRW 180
           DSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRW
Sbjct: 121 DSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRW 180

Query: 181 GRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW 220
           GRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW
Sbjct: 181 GRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW 220


>gi|239746776 PREDICTED: hypothetical protein XP_002343846 [Homo
           sapiens]
          Length = 210

 Score =  294 bits (752), Expect = 5e-80
 Identities = 138/138 (100%), Positives = 138/138 (100%)

Query: 83  VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS
Sbjct: 73  VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 132

Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202
           VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP
Sbjct: 133 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 192

Query: 203 LSSRVSLYELLFPSWPPW 220
           LSSRVSLYELLFPSWPPW
Sbjct: 193 LSSRVSLYELLFPSWPPW 210


>gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo
           sapiens]
          Length = 225

 Score =  287 bits (734), Expect = 6e-78
 Identities = 136/138 (98%), Positives = 136/138 (98%)

Query: 83  VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           VV PP SPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS
Sbjct: 88  VVLPPRSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 147

Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202
           VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP
Sbjct: 148 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 207

Query: 203 LSSRVSLYELLFPSWPPW 220
           LSSRVSLYELLFPSWPPW
Sbjct: 208 LSSRVSLYELLFPSWPPW 225



 Score =  126 bits (316), Expect = 2e-29
 Identities = 76/124 (61%), Positives = 79/124 (63%), Gaps = 4/124 (3%)

Query: 83  VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           VV P  SPDSVV P RSPDSVV PPGSPDSVVLP RSPDSVVPPPGSPDSVVLPPRSPDS
Sbjct: 18  VVLPSRSPDSVVLPSRSPDSVVLPPGSPDSVVLPSRSPDSVVPPPGSPDSVVLPPRSPDS 77

Query: 143 VVPPARSPDSGG-RAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQV---PSRPPS 198
           VVPP  SPDS      SP S+ PP  +     P        V   RSP  V   P  P S
Sbjct: 78  VVPPPGSPDSVVLPPRSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDS 137

Query: 199 LSQP 202
           +  P
Sbjct: 138 VVLP 141



 Score = 90.1 bits (222), Expect = 1e-18
 Identities = 62/117 (52%), Positives = 65/117 (55%), Gaps = 4/117 (3%)

Query: 90  PDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARS 149
           P SV     S  SVV P  SPDSVVLP RSPDSVV PPGSPDSVVLP RSPDSVVPP  S
Sbjct: 5   PVSVGSTWPSTHSVVLPSRSPDSVVLPSRSPDSVVLPPGSPDSVVLPSRSPDSVVPPPGS 64

Query: 150 PDSGG-RAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQV---PSRPPSLSQP 202
           PDS      SP S+ PP  +              VP  RSP  V   P  P S+  P
Sbjct: 65  PDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPRSPDSVVPPPGSPDSVVLP 121


>gi|239757968 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 157

 Score =  162 bits (409), Expect = 3e-40
 Identities = 77/82 (93%), Positives = 79/82 (96%)

Query: 139 SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198
           +P SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS
Sbjct: 3   APYSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 62

Query: 199 LSQPLSSRVSLYELLFPSWPPW 220
           LSQPLSSRVSL+ELL PS PPW
Sbjct: 63  LSQPLSSRVSLHELLLPSRPPW 84


>gi|239747023 PREDICTED: hypothetical protein XP_002343907 [Homo
           sapiens]
          Length = 157

 Score =  162 bits (409), Expect = 3e-40
 Identities = 77/82 (93%), Positives = 79/82 (96%)

Query: 139 SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198
           +P SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS
Sbjct: 3   APYSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 62

Query: 199 LSQPLSSRVSLYELLFPSWPPW 220
           LSQPLSSRVSL+ELL PS PPW
Sbjct: 63  LSQPLSSRVSLHELLLPSRPPW 84


>gi|239747021 PREDICTED: hypothetical protein XP_002343906 [Homo
           sapiens]
          Length = 157

 Score =  162 bits (409), Expect = 3e-40
 Identities = 77/82 (93%), Positives = 79/82 (96%)

Query: 139 SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198
           +P SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS
Sbjct: 3   APYSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 62

Query: 199 LSQPLSSRVSLYELLFPSWPPW 220
           LSQPLSSRVSL+ELL PS PPW
Sbjct: 63  LSQPLSSRVSLHELLLPSRPPW 84


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 7/120 (5%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           PP   P    PPP+ P    PPP  P S   P + P S  PPP  P      P+ P S  
Sbjct: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528

Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLS 204
           PP++ P S   +    S A P+A ++       G       +  P Q P+  PS  QP S
Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-------SGKPLQPPTVSPSAKQPPS 581



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 35/121 (28%), Positives = 44/121 (36%), Gaps = 7/121 (5%)

Query: 85  PPPGSPDSVVPP-PRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSV 143
           P PG P +  P   +S      PP  P  +  P       V PP  P     PP  P   
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--- 365

Query: 144 VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP--QVPSRPPSLSQ 201
           + PA+ P     +  P S  P   A A+  PG      + P    PP  QV +  P   Q
Sbjct: 366 LGPAKPPAQQTGSEKPSSEQPGPKALAQ-PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424

Query: 202 P 202
           P
Sbjct: 425 P 425



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 46/177 (25%), Positives = 70/177 (39%), Gaps = 30/177 (16%)

Query: 27   PSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPP 86
            P ++ L  T+ F   ++   + P + LP    ++ S     R    +S+ L + A+  PP
Sbjct: 2351 PMKEQLSTTY-FTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF-RSSSLDISAQPPPP 2408

Query: 87   PGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146
            P  P    PPP       PPP        PP  P   +PPP SP   +LP +      P 
Sbjct: 2409 PPPP----PPP-------PPP--------PPPPPPPPLPPPTSPKPTILPKKKLTVASPV 2449

Query: 147  ARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPL 203
              +        +  +L   A  R+ G P       R+    +PP VP +P S+   L
Sbjct: 2450 TTATP---LFDAVTTLETTAVLRSNGLP-----VTRI-CTTAPPPVPPKPSSIPSGL 2497



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 34/143 (23%), Positives = 49/143 (34%), Gaps = 32/143 (22%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPG-------------SPDS 132
           PP  P  +  P       V PP  P     PP  P     PP               P +
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390

Query: 133 VVLPP---RSPDSVVPPARSPDSGGRAGSPRSLA-------PPAAARAEGAPGWAGRWGR 182
           +  PP   ++P     PA+ P    + G+P+ LA       P  A      P      G+
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQ--QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448

Query: 183 VPLARSPP-------QVPSRPPS 198
           +P  ++ P         P++PPS
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPS 471



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 39/147 (26%), Positives = 54/147 (36%), Gaps = 12/147 (8%)

Query: 71  LCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSP 130
           L +   L+  AK   P  +P     P + P     P G   +    P  P S +P P  P
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKP 479

Query: 131 DSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP 190
                PP+ P     PA+ P     +  P S  P +       PG A    + P +  PP
Sbjct: 480 -----PPQQPG----PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530

Query: 191 --QVPSRPPSLSQPLSSRVSLYELLFP 215
             Q  S  PS  QP  ++ S  +   P
Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKP 557



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 8/80 (10%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           P P  P S  PP + P S  P    P       +     V   GS       P  P +V 
Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG-----KPLQPPTVS 573

Query: 145 PPARSPDSGGRAGSPRSLAP 164
           P A+ P S    G P+++ P
Sbjct: 574 PSAKQPPS---QGLPKTICP 590



 Score = 28.5 bits (62), Expect = 4.7
 Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 3/71 (4%)

Query: 89   SPDSVVPPPRSPDSVVPPPGSPDSVVLPPRS---PDSVVPPPGSPDSVVLPPRSPDSVVP 145
            SP S + P ++ +S   P   P    + P+    PD    PP SP +  +  RS     P
Sbjct: 3625 SPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684

Query: 146  PARSPDSGGRA 156
             + + D   RA
Sbjct: 3685 LSPTADESSRA 3695



 Score = 28.1 bits (61), Expect = 6.1
 Identities = 23/116 (19%), Positives = 38/116 (32%), Gaps = 7/116 (6%)

Query: 82   KVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPD 141
            K  P P  P +   PP+S     P P     V    ++P +    P +  +  +     +
Sbjct: 965  KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024

Query: 142  SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
               PP +  DS      P+    P        P         PL ++   + S+ P
Sbjct: 1025 KKPPPIK--DSKSLTAEPQKAVLPTKLEKSPKPE-----STCPLCKTELNIGSKDP 1073


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 7/120 (5%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           PP   P    PPP+ P    PPP  P S   P + P S  PPP  P      P+ P S  
Sbjct: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528

Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLS 204
           PP++ P S   +    S A P+A ++       G       +  P Q P+  PS  QP S
Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-------SGKPLQPPTVSPSAKQPPS 581



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 35/121 (28%), Positives = 44/121 (36%), Gaps = 7/121 (5%)

Query: 85  PPPGSPDSVVPP-PRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSV 143
           P PG P +  P   +S      PP  P  +  P       V PP  P     PP  P   
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--- 365

Query: 144 VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP--QVPSRPPSLSQ 201
           + PA+ P     +  P S  P   A A+  PG      + P    PP  QV +  P   Q
Sbjct: 366 LGPAKPPAQQTGSEKPSSEQPGPKALAQ-PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424

Query: 202 P 202
           P
Sbjct: 425 P 425



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 46/177 (25%), Positives = 70/177 (39%), Gaps = 30/177 (16%)

Query: 27   PSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPP 86
            P ++ L  T+ F   ++   + P + LP    ++ S     R    +S+ L + A+  PP
Sbjct: 2351 PMKEQLSTTY-FTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF-RSSSLDISAQPPPP 2408

Query: 87   PGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146
            P  P    PPP       PPP        PP  P   +PPP SP   +LP +      P 
Sbjct: 2409 PPPP----PPP-------PPP--------PPPPPPPPLPPPTSPKPTILPKKKLTVASPV 2449

Query: 147  ARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPL 203
              +        +  +L   A  R+ G P       R+    +PP VP +P S+   L
Sbjct: 2450 TTATP---LFDAVTTLETTAVLRSNGLP-----VTRI-CTTAPPPVPPKPSSIPSGL 2497



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 34/143 (23%), Positives = 49/143 (34%), Gaps = 32/143 (22%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPG-------------SPDS 132
           PP  P  +  P       V PP  P     PP  P     PP               P +
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390

Query: 133 VVLPP---RSPDSVVPPARSPDSGGRAGSPRSLA-------PPAAARAEGAPGWAGRWGR 182
           +  PP   ++P     PA+ P    + G+P+ LA       P  A      P      G+
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQ--QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448

Query: 183 VPLARSPP-------QVPSRPPS 198
           +P  ++ P         P++PPS
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPS 471



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 39/147 (26%), Positives = 54/147 (36%), Gaps = 12/147 (8%)

Query: 71  LCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSP 130
           L +   L+  AK   P  +P     P + P     P G   +    P  P S +P P  P
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKP 479

Query: 131 DSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP 190
                PP+ P     PA+ P     +  P S  P +       PG A    + P +  PP
Sbjct: 480 -----PPQQPG----PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530

Query: 191 --QVPSRPPSLSQPLSSRVSLYELLFP 215
             Q  S  PS  QP  ++ S  +   P
Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKP 557



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 8/80 (10%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           P P  P S  PP + P S  P    P       +     V   GS       P  P +V 
Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG-----KPLQPPTVS 573

Query: 145 PPARSPDSGGRAGSPRSLAP 164
           P A+ P S    G P+++ P
Sbjct: 574 PSAKQPPS---QGLPKTICP 590



 Score = 28.5 bits (62), Expect = 4.7
 Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 3/71 (4%)

Query: 89   SPDSVVPPPRSPDSVVPPPGSPDSVVLPPRS---PDSVVPPPGSPDSVVLPPRSPDSVVP 145
            SP S + P ++ +S   P   P    + P+    PD    PP SP +  +  RS     P
Sbjct: 3625 SPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684

Query: 146  PARSPDSGGRA 156
             + + D   RA
Sbjct: 3685 LSPTADESSRA 3695



 Score = 28.1 bits (61), Expect = 6.1
 Identities = 23/116 (19%), Positives = 38/116 (32%), Gaps = 7/116 (6%)

Query: 82   KVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPD 141
            K  P P  P +   PP+S     P P     V    ++P +    P +  +  +     +
Sbjct: 965  KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024

Query: 142  SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
               PP +  DS      P+    P        P         PL ++   + S+ P
Sbjct: 1025 KKPPPIK--DSKSLTAEPQKAVLPTKLEKSPKPE-----STCPLCKTELNIGSKDP 1073


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 53/144 (36%), Positives = 65/144 (45%), Gaps = 27/144 (18%)

Query: 79  VGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSV---VLPPRSPDSVVPPPGSPDSVVL 135
           +G   +PPP  P S +PPP      +PPP  P S+   V+PP  P + VPPPG P  V +
Sbjct: 511 MGNMSMPPPFVPYSQMPPPLP---TMPPPVLPPSLPPPVMPPALP-ATVPPPGMPPPV-M 565

Query: 136 PPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSR 195
           PP  P SV PP   P S   AG P  L PP+ +                 A  PP +P  
Sbjct: 566 PPSLPTSVPPPGMPP-SLSSAGPPPVLPPPSLSS----------------AGPPPVLP-- 606

Query: 196 PPSLSQPLSSRVSLYELLFPSWPP 219
           PPSLS      V     L  + PP
Sbjct: 607 PPSLSSTAPPPVMPLPPLSSATPP 630



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 48/141 (34%), Positives = 54/141 (38%), Gaps = 30/141 (21%)

Query: 84  VPPPGSPDSVVPPPRSPDSVVPPPGSPDSV---------------------VLPPRSPDS 122
           VPPPG P  V+PP  S  + VPPPG P S+                     VLPP S  S
Sbjct: 555 VPPPGMPPPVMPP--SLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSS 612

Query: 123 VVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSL-APPAAARAEGAPGWAGRWG 181
             PPP  P    LPP S  S  PP   P  G   G P  L A P    +           
Sbjct: 613 TAPPPVMP----LPPLS--SATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKP 666

Query: 182 RVPLARSPPQVPSRPPSLSQP 202
           R  L  +P    S PP+   P
Sbjct: 667 RPALLPTPVSFGSAPPTTYHP 687



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 46/143 (32%), Positives = 56/143 (39%), Gaps = 25/143 (17%)

Query: 80  GAKVVPPPGSPDSVVPPPRSP----DSVVPPPGSPDSVVLPPRS---PDSVVPPPGSPDS 132
           G   V PP S  S  PPP  P     S  PPP  P    LPP S   P   +PPPG P  
Sbjct: 586 GPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP----LPPLSSATPPPGIPPPGVPQG 641

Query: 133 VVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQV 192
           +  PP+   + VPPA S  S      PR    P       AP         P    PP  
Sbjct: 642 I--PPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAP---------PTTYHPPLQ 690

Query: 193 PSRPPSLSQPLSSRVSLYELLFP 215
            + P   S+ ++S+  L +   P
Sbjct: 691 SAGP---SEQVNSKAPLSKSALP 710



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 4/65 (6%)

Query: 85   PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
            PPPGS     P  + P S+V P   P    +P   P   +PPP  P    LPP  P  V+
Sbjct: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPP--LPP--PPPVI 1562

Query: 145  PPARS 149
             P  S
Sbjct: 1563 KPQTS 1567



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 48/174 (27%), Positives = 63/174 (36%), Gaps = 46/174 (26%)

Query: 85  PPPGSPDSVVP--------PPRSPDSVVPPPGS--------------------------P 110
           PPP  P  V+P        PP  P  + PPPG                           P
Sbjct: 83  PPPLPPPPVMPGGGYGDWQPP--PPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP 140

Query: 111 DSVVLPPRSPDSVVPPPGS----PDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPA 166
             +  PP SP     PPGS      S + PP+ P S  PP  S      A    S +PP+
Sbjct: 141 MELESPPESPP---VPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPS 197

Query: 167 AARAEGAPGW--AGRWGRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWP 218
            +     P +  +    +  L+ S   +PS   S S+P S   S  +LL P  P
Sbjct: 198 QSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRP-SQGHSKSQLLAPPPP 250



 Score = 36.6 bits (83), Expect = 0.017
 Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 6/122 (4%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP 145
           PP  P S +PP +S    +PPP  P S   PP S    +PP     S   P +S  +  P
Sbjct: 150 PPVPPGSYMPPSQS---YMPPPQPPPSYY-PPTSSQPYLPPAQPSPSQSPPSQSYLAPTP 205

Query: 146 PARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVP--SRPPSLSQPL 203
              S  S  ++    S +   +++A  +    G      LA  PP  P  ++     +PL
Sbjct: 206 SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPL 265

Query: 204 SS 205
            S
Sbjct: 266 ES 267



 Score = 32.0 bits (71), Expect = 0.43
 Identities = 28/85 (32%), Positives = 32/85 (37%), Gaps = 21/85 (24%)

Query: 55  WSKNALFSKVVFIRVHL---------CKSTVLRVGAKVVPP-----PGSPDSVVPPPRSP 100
           W +  L S     +VHL          K T   V  +V  P     P SP S  PP   P
Sbjct: 297 WYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPP 356

Query: 101 DSVVPPPGSPDSVVLPPRSPDSVVP 125
           +  VPPP       LPP  P S  P
Sbjct: 357 NEEVPPP-------LPPEEPQSEDP 374



 Score = 31.6 bits (70), Expect = 0.56
 Identities = 32/117 (27%), Positives = 44/117 (37%), Gaps = 13/117 (11%)

Query: 90  PDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARS 149
           P  + PPP  P  V+P  G  D    PP  P    PPPG   S     +    ++   R 
Sbjct: 78  PHHLPPPPLPPPPVMPGGGYGDWQPPPPPMP----PPPGPALSYQKQQQYKHQMLHHQRD 133

Query: 150 PDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLSSR 206
                  G P  +     +  E  P   G +  +P ++S    P  PPS   P SS+
Sbjct: 134 -------GPPGLVPMELESPPESPPVPPGSY--MPPSQSYMPPPQPPPSYYPPTSSQ 181



 Score = 30.0 bits (66), Expect = 1.6
 Identities = 28/94 (29%), Positives = 37/94 (39%), Gaps = 8/94 (8%)

Query: 84  VPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPP---GSPDSVVLPPRSP 140
           +PPP  P S  PP  S   +  PP  P     PP S   + P P    S  S        
Sbjct: 165 MPPPQPPPSYYPPTSSQPYL--PPAQPSPSQSPP-SQSYLAPTPSYSSSSSSSQSYLSHS 221

Query: 141 DSVVPPARSPDSGGRAGSPRS--LAPPAAARAEG 172
            S +P +++  S    G  +S  LAPP  +   G
Sbjct: 222 QSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPG 255



 Score = 28.9 bits (63), Expect = 3.6
 Identities = 32/163 (19%), Positives = 58/163 (35%), Gaps = 22/163 (13%)

Query: 10   ISNECQWHLNQLSDHTEPSE--------QHLPGTHAFAEVQSRSSKFPTN-------TLP 54
            + +   W   +LSD   PS+        +H+P +H  +E+    +   ++        L 
Sbjct: 1390 VPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLS 1449

Query: 55   WSKNALFSKVVF-IRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPR------SPDSVVPPP 107
              ++ +  K    +++   +   L+        P   D + P         S   + PPP
Sbjct: 1450 QRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPP 1509

Query: 108  GSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSP 150
            GS        + P S+V P   P    +P   P   +PP   P
Sbjct: 1510 GSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP 1552



 Score = 28.5 bits (62), Expect = 4.7
 Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 1/30 (3%)

Query: 110  PDSVVLPPRSPDSVVPPPGSPDSVVLPPRS 139
            P + VLPP    S +PPPG P  + +PP S
Sbjct: 1603 PSAPVLPPPPVHSSIPPPG-PVPMGMPPMS 1631



 Score = 27.7 bits (60), Expect = 8.0
 Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 5/38 (13%)

Query: 90   PDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPP 127
            P + V PP    S +PPPG P  + +PP S     PPP
Sbjct: 1603 PSAPVLPPPPVHSSIPPPG-PVPMGMPPMSK----PPP 1635


>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
          Length = 616

 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 43/136 (31%), Positives = 58/136 (42%), Gaps = 4/136 (2%)

Query: 72  CKSTVLRVG--AKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDS--VVPPP 127
           C+  VLR    A+  PPP   D   PP   P  ++P P +    +LPP  P    + PP 
Sbjct: 329 CRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPM 388

Query: 128 GSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187
           G    V  PP S ++V PP+ S      +G+  + A   +A A  A       G  P A 
Sbjct: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 448

Query: 188 SPPQVPSRPPSLSQPL 203
             P  P  PP +  PL
Sbjct: 449 PAPGFPFPPPWMGMPL 464


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 10/138 (7%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPPPGSPDSVVLPP-RSPDS 142
           PP SP S  PP ++P S+  PP    P     PP SP S  PPP +P  +  PP + P S
Sbjct: 683 PPVSP-SATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQVPPS 740

Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202
             PPA  P S      PR     AA   +  P         PLA+ PPQ    PP+L+ P
Sbjct: 741 --PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA---PPALATP 795

Query: 203 LSSRVSLYELLFPSWPPW 220
               +      FP   P+
Sbjct: 796 PLQALPSPPASFPGQAPF 813



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 49/135 (36%), Positives = 56/135 (41%), Gaps = 26/135 (19%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPP--GSPDSVVLPPRSPDSVVPPPGSPDSVVLPP-RSPDS 142
           PP SP +  PPP++P  +  PP    P     PP SP S  PPP  P  +  PP + P S
Sbjct: 714 PPMSPSA-TPPPQAPPPLAAPPLQVPPSPPASPPMSP-SATPPPRVPPLLAAPPLQVPPS 771

Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAAR---------AEGAPGWA-----GRWGRVPLARS 188
             PPA  P S      P   APPA A              PG A           PLA  
Sbjct: 772 --PPASLPMS--PLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827

Query: 189 PPQVPSRPPSLSQPL 203
           PPQ    PP L+ PL
Sbjct: 828 PPQA---PPVLAAPL 839



 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 42/131 (32%), Positives = 54/131 (41%), Gaps = 17/131 (12%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVL--------PP 137
           PP SP +  PP   P   +PP  +P S    P       P P +P+++ +        PP
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668

Query: 138 RSPD---SVVPPARSPDSGGRAGSPRSLAPP--AAARAEGAPGWAGRWGRVPLARSPPQV 192
            SP       PPA  P S   + +P S APP  AA   +  P         P A  PPQ 
Sbjct: 669 PSPPVQAPFSPPASPPVS--PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726

Query: 193 PSRPPSLSQPL 203
           P  PP  + PL
Sbjct: 727 P--PPLAAPPL 735



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 44/143 (30%), Positives = 58/143 (40%), Gaps = 13/143 (9%)

Query: 87  PGSPDSVVPPPRSPDSVV-PPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP 145
           P SP    PPP +P S+  PPP +P ++  PP     +  PP SP +   P   P   +P
Sbjct: 572 PPSP-LTTPPPETPSSIATPPPQAPPALASPPLQ--GLPSPPLSPLATPPPQAPPXLALP 628

Query: 146 PARSPDSGGRAGSPRSLAPPA-------AARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198
           P ++P S   +     LA P+       A     AP        V    SPP  P   PS
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688

Query: 199 LSQPLSSRVSLY--ELLFPSWPP 219
            + P  +  SL    L  P  PP
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPP 711



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 44/142 (30%), Positives = 59/142 (41%), Gaps = 33/142 (23%)

Query: 85  PPPGSPDSVVPPPRSPDS----------VVPPPGSPDSVVL--------PPRSPDSVVP- 125
           PP   P   +PP ++P S            P P +P+++ +        PP SP    P 
Sbjct: 618 PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677

Query: 126 -PPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAP--PAAARAEGAPGWAGRWGR 182
            PP SP   V P  +P S  PP+ +        SP +  P  P+A     AP        
Sbjct: 678 SPPASPP--VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP-------- 727

Query: 183 VPLARSPPQVPSRPPSLSQPLS 204
            PLA  P QVP  PP+ S P+S
Sbjct: 728 PPLAAPPLQVPPSPPA-SPPMS 748



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 51/164 (31%), Positives = 73/164 (44%), Gaps = 34/164 (20%)

Query: 81  AKVVPPPGSPDSVVPP--PRSPDSVVPPPGSPDSVVLPPR-----SPDSVVPPPGSPDSV 133
           A+ VPPP +  + +P   P SP    P P +P S   PP      SP +  PP  +P S+
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA-TPPSQAPPSM 372

Query: 134 VLPP-RSPDSV--VPPARSPDSGGRAGSPRSLAPPA--------AARAEGAPGWAGRWGR 182
             PP ++P S+  +PP + P S     SP   APP+        A  + G+P        
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHS---LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429

Query: 183 VPLARSPPQV----PSRP---PSLSQPLSSRVSLYELLFPSWPP 219
           + ++    Q     PSRP   P  S PL + +SL     P+ PP
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL-----PASPP 468



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 46/127 (36%), Positives = 57/127 (44%), Gaps = 22/127 (17%)

Query: 86  PPGSPDSVVP--PPRSPD---SVVPPPGSPDSVVLPP-RSPDSVVPPPGSPDSVVLPPRS 139
           PP SP    P  PP SP    S  PP  +P S+  PP + P S   PP SP   + P  +
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS---PPASPP--MSPSAT 721

Query: 140 PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVP--LARSPPQVPSRPP 197
           P    PP  +        SP + +PP +  A   P       RVP  LA  P QVP  PP
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPA-SPPMSPSATPPP-------RVPPLLAAPPLQVPPSPP 773

Query: 198 SLSQPLS 204
           + S P+S
Sbjct: 774 A-SLPMS 779



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 22/122 (18%)

Query: 85  PPPGSPDSVVPPP--------RSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLP 136
           PP  +  S+ PPP         +P    PP  +P  +  PP SP    PPP +P S+  P
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP-SP-LTTPPPETPSSIATP 590

Query: 137 P-RSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSR 195
           P ++P ++     SP   G    P  L+P A    +  P  A     +P  ++PP  P+ 
Sbjct: 591 PPQAPPALA----SPPLQGLPSPP--LSPLATPPPQAPPXLA-----LPPLQAPPSPPAS 639

Query: 196 PP 197
           PP
Sbjct: 640 PP 641



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 45/151 (29%), Positives = 58/151 (38%), Gaps = 26/151 (17%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSV------VPPPGSPDSVVLP--- 136
           PP SP   + P  +P   VPP  +   + +PP  P S+       PPP +P ++  P   
Sbjct: 741 PPASPP--MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798

Query: 137 --PRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP---- 190
             P  P S    A    S     SP +  PP A     AP        + +  SPP    
Sbjct: 799 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LLQVPPSPPASPT 851

Query: 191 -QVPSRPPSLSQPLS-SRVSLYELLFPSWPP 219
            Q P RPP+     S S   L   L P  PP
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 11/122 (9%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           PP   PD+ V  PR   ++ P P  P     P RSP S +  P           +P+ + 
Sbjct: 858 PPTPGPDTSVSGPRLTLALAPGPPPP-----PSRSPSSTLSGPDLAGHSSSATSTPEEL- 911

Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA-RSPPQVPSRPPSLSQPL 203
              R  DSG   G+  S  PP A  A   P    R    PLA R  P  P   P  + P 
Sbjct: 912 ---RGYDSGPEGGAAAS-PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 967

Query: 204 SS 205
           S+
Sbjct: 968 SA 969



 Score = 34.7 bits (78), Expect = 0.066
 Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 13/117 (11%)

Query: 82  KVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPD 141
           +V PP       + P  S     P P    +  +PP  PD+      +P    LPP SP 
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP--PDNA----ATPLPATLPP-SPP 336

Query: 142 SVVPPARSPDSGGRAGSPRSL-APPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
              P   +P S     S ++L +PPA   ++  P         P  ++PP + + PP
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT-----TPPMQAPPSLQTIPP 388



 Score = 33.1 bits (74), Expect = 0.19
 Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 14/103 (13%)

Query: 100 PDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSP 159
           P  V PP       + P  S     P P    +  +PP    +   PA  P S   A +P
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA-TP 340

Query: 160 RSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202
             LAPP+ +    AP         P  ++ P  P+ PPS + P
Sbjct: 341 LPLAPPSPS----AP---------PSLQTLPSPPATPPSQAPP 370



 Score = 28.9 bits (63), Expect = 3.6
 Identities = 32/115 (27%), Positives = 42/115 (36%), Gaps = 17/115 (14%)

Query: 80   GAKVVPPPGSPDSVVPPPRSPDSVVPP------PGSPDSVVLPPRSPDSVVPPPGSPDSV 133
            GA   PPP +  +   P        PP      PG+P  +  PP +       PGS D +
Sbjct: 921  GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP--LPWPPAT------GPGSADGL 972

Query: 134  --VLPPRSPDSVVPPARSPDSGGRAG-SPRSLAPPAAARAEGAPGWAGRWGRVPL 185
              +     P+S  P   + D G   G S    A  A A A        R G +PL
Sbjct: 973  CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 1027


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 27/176 (15%)

Query: 36  HAFAEVQSRSSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVP 95
           HA A   S  +  P   LP  K A    V+         T   VGA   P P +P     
Sbjct: 209 HAAAPAVSLVNNGPAALLPLPKPAAPGTVI--------QTPPFVGAAAPPAPAAPSPPAA 260

Query: 96  PPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGR 155
           P  +  +  PPP        PP +P ++  PPG P     PP +  +V PPA +  +GG 
Sbjct: 261 PAPAAPAAAPPP--------PPPAPATLARPPGHPAG---PPTAAPAVPPPA-AAQNGGS 308

Query: 156 AGSPRSLAPPAA--ARAEGAPGWAGRWGRVPL----ARSPPQVPSRPPSLSQPLSS 205
           AG+  + AP A   A   G PG  G     P     A SP +V    P  +Q L++
Sbjct: 309 AGAAPAPAPAAGGPAGVSGQPG-PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA 363



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 5/73 (6%)

Query: 135 LPPRSPDSVVPPARSPDSGGRAGSPRSLAPPA-AARAEGAPGWAGR---WGRVPLARSPP 190
           L PR+P+     A +  +   +GSP   A    AA AEGAPG A      GR       P
Sbjct: 43  LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102

Query: 191 QVPSRPPSLSQPL 203
           Q P  PPS  +PL
Sbjct: 103 QRPG-PPSPRRPL 114


>gi|27436927 synoviolin 1 isoform b [Homo sapiens]
          Length = 617

 Score = 57.8 bits (138), Expect = 7e-09
 Identities = 44/137 (32%), Positives = 60/137 (43%), Gaps = 5/137 (3%)

Query: 72  CKSTVLRVG--AKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPD--SVVPPP 127
           C+  VLR    A+  PPP   D   PP   P  ++P P +    +LPP  P    + PP 
Sbjct: 329 CRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPM 388

Query: 128 GSPDSVVLPPRSPDSVVPPARSPDSGGR-AGSPRSLAPPAAARAEGAPGWAGRWGRVPLA 186
           G    V  PP S ++V PP+ S  +  R +G+  + A   +A A  A       G  P A
Sbjct: 389 GPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEA 448

Query: 187 RSPPQVPSRPPSLSQPL 203
              P  P  PP +  PL
Sbjct: 449 GPAPGFPFPPPWMGMPL 465



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 4/112 (3%)

Query: 86  PPGSPDSVVPP-PRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           PP  P  ++PP P     + PP G    V  PP S ++V PP  S  ++  P  +  +  
Sbjct: 366 PPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTA 425

Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEG---APGWAGRWGRVPLARSPPQVP 193
               +  +   A  P S + P A  A G    P W G     P A  P  VP
Sbjct: 426 AGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVP 477


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 47/147 (31%), Positives = 57/147 (38%), Gaps = 8/147 (5%)

Query: 77  LRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLP 136
           L  G  ++PPP  P  ++PPP  P S  PPP  P S  LPP       PPP  P S  + 
Sbjct: 463 LHQGKGMMPPP--PMGMMPPPPPPPSGQPPP--PPSGPLPPWQQQQQQPPPPPPPSSSMA 518

Query: 137 PRSPDSVVPPARSPDSGGRAGS--PRSLAPPAAARAEGAPGWAGRWGRVPL--ARSPPQV 192
             +P        +  +    GS  P      AAA + GAP   G    VPL     PP  
Sbjct: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLP 578

Query: 193 PSRPPSLSQPLSSRVSLYELLFPSWPP 219
           P  PP    P      +     P  PP
Sbjct: 579 PGAPPPPPPPPPGSAGMMYAPPPPPPP 605



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 42/143 (29%), Positives = 50/143 (34%), Gaps = 47/143 (32%)

Query: 45  SSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPP-----------PGSPDSV 93
           SS   +  LPW +N               +T    G   +PP           PG+P   
Sbjct: 515 SSMASSTPLPWQQNTT-------------TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQ 561

Query: 94  VPPPRSP--DSVVPP--PGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARS 149
             P   P    V PP  PG+P     PP  P    PPPGS   +  PP  P    PP   
Sbjct: 562 GNPTMVPLPPGVQPPLPPGAP-----PPPPP----PPPGSAGMMYAPPPPP----PPPMD 608

Query: 150 PDS------GGRAGSPRSLAPPA 166
           P +       G AG P    PPA
Sbjct: 609 PSNFVTMMGMGVAGMPPFGMPPA 631



 Score = 33.1 bits (74), Expect = 0.19
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPP 137
           PPPGS   +  PP  P    PPP  P + V       + +PP G P +   PP
Sbjct: 588 PPPGSAGMMYAPPPPP----PPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPP 636



 Score = 27.7 bits (60), Expect = 8.0
 Identities = 28/117 (23%), Positives = 40/117 (34%), Gaps = 6/117 (5%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           P P S  S   P  +P +  P P +P +   PP    +    P   +S     R    + 
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGM- 382

Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQ 201
                   GG  G P S   P  +   G  G   +    P    PP +   PP ++Q
Sbjct: 383 ---HGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN--PNGPPPPWMQPPPPPMNQ 434


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 20/126 (15%)

Query: 85  PPPGSPDSVVPPP---RSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVL-----P 136
           PPP  P S  PPP   + P+ VV  P + ++   P + P+   PPP +P+   L     P
Sbjct: 729 PPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP 788

Query: 137 PRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRP 196
           P  P+       SP+  G +GSP  ++ PAA+ +              L   PP  P  P
Sbjct: 789 P--PEEAFFSVASPEPAGPSGSPELVSSPAASSSSA----------TALQIQPPGSPDPP 836

Query: 197 PSLSQP 202
           P+   P
Sbjct: 837 PAPPAP 842



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 44/130 (33%), Positives = 54/130 (41%), Gaps = 20/130 (15%)

Query: 86  PPGSPDSVVPPPRSPDSV----VPPPGSPDSVVLPPRSPDSVVPPPGSPDSVV-LPPRSP 140
           P GSP+ V  P  S  S     + PPGSPD    PP +P +  P   +P  V  LP + P
Sbjct: 805 PSGSPELVSSPAASSSSATALQIQPPGSPD----PPPAPPAPAPASSAPGHVAKLPQKEP 860

Query: 141 DSVVPPARSP--DSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198
                    P  D G    +P SL      R+ GAPG A      P     P  P +P  
Sbjct: 861 VGCSKGGGPPREDVGAPLVTP-SLLQMVRLRSVGAPGGA------PTPALGPSAPQKP-- 911

Query: 199 LSQPLSSRVS 208
           L + LS R S
Sbjct: 912 LRRALSGRAS 921



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 36/147 (24%), Positives = 57/147 (38%), Gaps = 25/147 (17%)

Query: 78  RVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDS--VVLPPRSPDSVVP-PPGSPDSVV 134
           R G +++ P G    + P P+ P    PPP  P S     P  +  +VVP P  + D+  
Sbjct: 645 RSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASP 704

Query: 135 LPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPS 194
             P +P + + P +      +  SP    PP                    +  PP  P+
Sbjct: 705 QSPPTPQTTLTPLQESPVISKDQSPPPSPPP--------------------SYHPPPPPT 744

Query: 195 RPPS--LSQPLSSRVSLYELLFPSWPP 219
           + P   +  P +S  +   L  P+WPP
Sbjct: 745 KKPEVVVEAPSASETAEEPLQDPNWPP 771



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 38/137 (27%), Positives = 53/137 (38%), Gaps = 8/137 (5%)

Query: 84  VPPPGSPDSVVPPPRSPDSVVPPPGSPDSVV-LPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           + PPGSPD    PP +P +  P   +P  V  LP + P       G P   V  P    S
Sbjct: 827 IQPPGSPD----PPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882

Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202
           ++   R    G   G+P     P+A +       +GR   VP   S      R  + S  
Sbjct: 883 LLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA 942

Query: 203 LSSRVSLYELLFPSWPP 219
            S  +S  +   P+ PP
Sbjct: 943 ASEGLSSAQ---PNGPP 956



 Score = 34.7 bits (78), Expect = 0.066
 Identities = 36/142 (25%), Positives = 51/142 (35%), Gaps = 19/142 (13%)

Query: 80  GAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPG-SPDSVVLPPR 138
           GA   P P +P +   P  SP     PP SP+  + P     S    P   P  +  PP 
Sbjct: 544 GAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPA 603

Query: 139 SPDSVVPPARSPDSGGRA-GSPRSLAPPAAARAEGAPGWAGRWG---------------- 181
           SP    PP     +  R+ G+  S +  +   +   P  + R G                
Sbjct: 604 SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPH 663

Query: 182 -RVPLARSPPQVPSRPPSLSQP 202
            +VP   SPP    R P+ + P
Sbjct: 664 PKVPAPFSPPPSKPRSPNPAAP 685



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 30/107 (28%), Positives = 39/107 (36%), Gaps = 24/107 (22%)

Query: 67   IRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSV-------------VPPPGSPD-- 111
            +R+  C S     G     P G P++   PP+SP S              +  P SP+  
Sbjct: 934  VRLKAC-SLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQ 992

Query: 112  -----SVVLPPRSPDSVVPPPGSPDSVVLPP---RSPDSVVPPARSP 150
                 ++V   RS     PP     S   PP   R P   VPP  SP
Sbjct: 993  ADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASP 1039



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 16/41 (39%), Positives = 18/41 (43%), Gaps = 4/41 (9%)

Query: 86   PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 126
            P  SP +  P  R P   VPPP SP      PR+     PP
Sbjct: 1015 PKKSPKAPPPVARKPSVGVPPPASPSY----PRAEPLTAPP 1051



 Score = 27.7 bits (60), Expect = 8.0
 Identities = 20/58 (34%), Positives = 23/58 (39%), Gaps = 7/58 (12%)

Query: 92   SVVPPPRSPDSVVPPPGSPDSVVLPP---RSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146
            ++V   RS     PP     S   PP   R P   VPPP SP      PR+     PP
Sbjct: 998  NLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSY----PRAEPLTAPP 1051


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 41/118 (34%), Positives = 46/118 (38%), Gaps = 12/118 (10%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP--PPGSPDSVVLPPR---S 139
           PPPG P    P   +     PPPG P     PP+   S  P  PPG P     PP+    
Sbjct: 52  PPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQGP--PPQGGNQ 107

Query: 140 PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
           P    PP   P      G  R   PP   + +G P   G   R P  RSPP  P  PP
Sbjct: 108 PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP-QGDKSRSP--RSPPGKPQGPP 162



 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 38/129 (29%), Positives = 43/129 (33%), Gaps = 20/129 (15%)

Query: 85  PPP---GSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP----------PPGSPD 131
           PPP     P    PPP  P    P  G       PP  P    P          PPG P 
Sbjct: 161 PPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQ 220

Query: 132 SVVLPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARS 188
               PP+    P    PP   P      G  +   PP   + +G P   G   +   ARS
Sbjct: 221 GP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG--SKSQSARS 276

Query: 189 PPQVPSRPP 197
           PP  P  PP
Sbjct: 277 PPGKPQGPP 285



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 25/131 (19%)

Query: 85  PPP---GSPDSVVPPPRSPDSV----------VPPPGSPDSVVLPPRSPDSVVP--PPGS 129
           PPP     P    PPP  P              PPPG P     PP+   S  P  PPG 
Sbjct: 100 PPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP--PPQGDKSRSPRSPPGK 157

Query: 130 PDSVVLPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA 186
           P     PP+    P    PP   P      G  +   PP   + +G P    +  +   +
Sbjct: 158 PQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP---PQGDKSRSS 212

Query: 187 RSPPQVPSRPP 197
           +SPP  P  PP
Sbjct: 213 QSPPGKPQGPP 223



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 29/119 (24%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRS----PDSVVPPPGSPDSVVLPPRSP 140
           PPPG P    P   +     PPPG P     PP        S   PPG P      P   
Sbjct: 235 PPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPAQGGSKSQSARSPPGKPQG----PPQQ 287

Query: 141 DSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQ--VPSRPP 197
           +   P    P +GG    P++   P A + +G P              PPQ   PSRPP
Sbjct: 288 EGNNPQGPPPPAGGNPQQPQA---PPAGQPQGPP-------------RPPQGGRPSRPP 330



 Score = 35.4 bits (80), Expect = 0.038
 Identities = 32/111 (28%), Positives = 40/111 (36%), Gaps = 23/111 (20%)

Query: 88  GSPDSVVPPP-RSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146
           G+P    P     P    PPPG P              PPP   +     P+ P     P
Sbjct: 34  GNPQGPSPQGGNKPQGPPPPPGKPQG------------PPPQGGNK----PQGPPPPGKP 77

Query: 147 ARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
              P  G ++ SPRS  PP   + +G P   G   + P    PP  P  PP
Sbjct: 78  QGPPPQGDKSRSPRS--PP--GKPQGPPPQGGNQPQGP--PPPPGKPQGPP 122


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 44/130 (33%), Positives = 53/130 (40%), Gaps = 8/130 (6%)

Query: 77  LRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLP 136
           L  G  ++PPP  P  ++PPP  P S  PPP  P S  LPP       PPP  P S  + 
Sbjct: 463 LHQGKGMMPPP--PMGMMPPPPPPPSGQPPP--PPSGPLPPWQQQQQQPPPPPPPSSSMA 518

Query: 137 PRSPDSVVPPARSPDSGGRAGS--PRSLAPPAAARAEGAPGWAGRWGRVPL--ARSPPQV 192
             +P        +  +    GS  P      AAA + GAP   G    VPL     PP  
Sbjct: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLP 578

Query: 193 PSRPPSLSQP 202
           P  PP    P
Sbjct: 579 PGAPPPPPPP 588



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 38/149 (25%)

Query: 45  SSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPP-----------PGSPDSV 93
           SS   +  LPW +N               +T    G   +PP           PG+P   
Sbjct: 515 SSMASSTPLPWQQNTT-------------TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQ 561

Query: 94  VPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSG 153
             P   P   +PP   P    LPP +P    PPP     +++PPR  D   P   S D  
Sbjct: 562 GNPTMVP---LPPGVQPP---LPPGAPPPPPPPPPGSAGMMIPPRGGDG--PSHESED-- 611

Query: 154 GRAGSPRSLAPPAAARAEGAPGWAGRWGR 182
                PR L      + +  P W G +G+
Sbjct: 612 ----FPRPLVTLPGRQPQQRPWWTGWFGK 636



 Score = 27.7 bits (60), Expect = 8.0
 Identities = 28/117 (23%), Positives = 40/117 (34%), Gaps = 6/117 (5%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           P P S  S   P  +P +  P P +P +   PP    +    P   +S     R    + 
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGM- 382

Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQ 201
                   GG  G P S   P  +   G  G   +    P    PP +   PP ++Q
Sbjct: 383 ---HGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN--PNGPPPPWMQPPPPPMNQ 434


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 39/120 (32%), Positives = 45/120 (37%), Gaps = 14/120 (11%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPD----SVVPPPGSPDSVVLPPR-- 138
           PPPG P    P   +     PPPG P     PP   D    S   PPG P     PP+  
Sbjct: 196 PPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDNKSQSARSPPGKPQGP--PPQGG 250

Query: 139 -SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
             P    PP   P      G  +   PP   + +G P   G   R   +RSPP  P  PP
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR--SSRSPPGKPQGPP 308



 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 39/130 (30%), Positives = 44/130 (33%), Gaps = 21/130 (16%)

Query: 85  PPP---GSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP-----------PPGSP 130
           PPP     P    PPP  P    P  G+      PP  P    P           PPG P
Sbjct: 245 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKP 304

Query: 131 DSVVLPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187
                PP+    P    PP   P      G  +   PP   + +G P   G   R   AR
Sbjct: 305 QGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR--SAR 360

Query: 188 SPPQVPSRPP 197
           SPP  P  PP
Sbjct: 361 SPPGKPQGPP 370



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 38/122 (31%), Positives = 45/122 (36%), Gaps = 20/122 (16%)

Query: 86  PPGSPDSVVPPPRS---PDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           PPG P    PPP+    P    PPPG P        +     PPPG P     PP   D+
Sbjct: 176 PPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDN 230

Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGR-------WGRVPLARSPPQVPSR 195
               ARSP      G P+   P    + +G P   G+        G  P    PP  P  
Sbjct: 231 KSQSARSP-----PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 285

Query: 196 PP 197
           PP
Sbjct: 286 PP 287



 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 40/131 (30%), Positives = 46/131 (35%), Gaps = 24/131 (18%)

Query: 85  PPP---GSPDSVVPPPRSPDSV----------VPPPGSPDSVVLPPRSPDSVVP--PPGS 129
           PPP     P    PPP  P              PPPG P     PP+   S  P  PPG 
Sbjct: 60  PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGK 117

Query: 130 PDSVVLPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA 186
           P     PP+    P    PP   P      G  +   PP   + +G P       R   +
Sbjct: 118 PQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR--SS 173

Query: 187 RSPPQVPSRPP 197
           RSPP  P  PP
Sbjct: 174 RSPPGKPQGPP 184



 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 35/120 (29%), Positives = 45/120 (37%), Gaps = 16/120 (13%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPP---RSPDSVVPPPGSPDSVVLPP----- 137
           PPG P    PPP+  +    PP  P     PP    +     PPPG P     PP     
Sbjct: 114 PPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDN 168

Query: 138 RSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
           +S  S  PP +      + G+     PP   + +G P    + G  P    PP  P  PP
Sbjct: 169 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP---PQGGNKPQGPPPPGKPQGPP 225



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 38/122 (31%), Positives = 46/122 (37%), Gaps = 35/122 (28%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPD---SVVPPPGSPDSVVLPPR--- 138
           PPPG P    P   +     PPPG P     PP+      S   PPG P     PP+   
Sbjct: 320 PPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGGSKSRSARSPPGKPQG---PPQQEG 374

Query: 139 -SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQ--VPSR 195
            +P    PPA         G+P+    P A + +G P              PPQ   PSR
Sbjct: 375 NNPQGPPPPA--------GGNPQQPQAPPAGQPQGPP-------------RPPQGGRPSR 413

Query: 196 PP 197
           PP
Sbjct: 414 PP 415



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 37/126 (29%), Positives = 43/126 (34%), Gaps = 26/126 (20%)

Query: 85  PPPGSPDSVVP----------PPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVV 134
           PPPG P    P          PP  P     PP   D+     RS      PPG P    
Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDNKSRSSRS------PPGKPQGP- 183

Query: 135 LPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQ 191
            PP+    P    PP   P      G  +   PP   + +G P       +   ARSPP 
Sbjct: 184 -PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD--NKSQSARSPPG 240

Query: 192 VPSRPP 197
            P  PP
Sbjct: 241 KPQGPP 246



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 36/115 (31%), Positives = 43/115 (37%), Gaps = 13/115 (11%)

Query: 85  PPPGS--PDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           PP G   P     PP  P    PPP   +    PP  P     P G P      P+ P  
Sbjct: 40  PPQGGNKPQGPPSPPGKPQG--PPPQGGNQPQGPPPPPGK---PQGPPPQGGNKPQGPPP 94

Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
              P   P  G ++ SPRS  PP   + +G P   G   + P    PP  P  PP
Sbjct: 95  PGKPQGPPPQGDKSRSPRS--PP--GKPQGPPPQGGNQPQGP--PPPPGKPQGPP 143


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 31/220 (14%)

Query: 6   SQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNALFSKVV 65
           S++T  +E Q  + ++    E   Q L G       + +        L    + L  +V 
Sbjct: 481 SELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVA 540

Query: 66  FIRVHL---CKSTVLRVGAKVVPPPGSPDSVVPPPRSP-----DSVVPPPGSPDSVVLPP 117
            +   L    K       A +  PP  P     PP  P      +++PPP +P     PP
Sbjct: 541 KLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP 600

Query: 118 RSPDSVVPPPGSPDSVVL---------------PPRSPDSVVPPARSPDSGGRAGSPRSL 162
             P    PPP  P  V +               PP S D+ +PP      G    SP SL
Sbjct: 601 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 660

Query: 163 APPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202
             P        P   G       AR PP  P  P S   P
Sbjct: 661 --PGGTAIPPPPPLPGS------ARIPPPPPPLPGSAGIP 692



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 39/117 (33%), Positives = 49/117 (41%), Gaps = 9/117 (7%)

Query: 83  VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVL--PPRSPDSVV---PPPGSPDSVVLPP 137
           ++PPP +P     PP  P    PPP  P  V +  PP  P       PPP S D+ + PP
Sbjct: 586 IIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP 645

Query: 138 RS-PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVP 193
              P+ V  P+ S   GG A  P    P +A      P   G  G  P    PP +P
Sbjct: 646 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP---PPPPLP 699



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 30/141 (21%)

Query: 80  GAKVVPP----PGSPDSVVPPPRSPDSV---VPPPGSPDSVVLPPRSP-----DSVVPPP 127
           G   +PP    PGS     PPP  P S     PPP  P    +PP  P       + PPP
Sbjct: 662 GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP 721

Query: 128 GSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187
             P    +PP  P   +PP                 PP       AP     +G  P   
Sbjct: 722 PFPGGPGIPPPPPGMGMPP----------------PPPFGFGVPAAP--VLPFGLTPKKL 763

Query: 188 SPPQVPSRPPSLSQPLSSRVS 208
             P+V  R P+ S+ ++  +S
Sbjct: 764 YKPEVQLRRPNWSKLVAEDLS 784


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 31/220 (14%)

Query: 6   SQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNALFSKVV 65
           S++T  +E Q  + ++    E   Q L G       + +        L    + L  +V 
Sbjct: 490 SELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVA 549

Query: 66  FIRVHL---CKSTVLRVGAKVVPPPGSPDSVVPPPRSP-----DSVVPPPGSPDSVVLPP 117
            +   L    K       A +  PP  P     PP  P      +++PPP +P     PP
Sbjct: 550 KLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP 609

Query: 118 RSPDSVVPPPGSPDSVVL---------------PPRSPDSVVPPARSPDSGGRAGSPRSL 162
             P    PPP  P  V +               PP S D+ +PP      G    SP SL
Sbjct: 610 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 669

Query: 163 APPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202
             P        P   G       AR PP  P  P S   P
Sbjct: 670 --PGGTAIPPPPPLPGS------ARIPPPPPPLPGSAGIP 701



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 39/117 (33%), Positives = 49/117 (41%), Gaps = 9/117 (7%)

Query: 83  VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVL--PPRSPDSVV---PPPGSPDSVVLPP 137
           ++PPP +P     PP  P    PPP  P  V +  PP  P       PPP S D+ + PP
Sbjct: 595 IIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP 654

Query: 138 RS-PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVP 193
              P+ V  P+ S   GG A  P    P +A      P   G  G  P    PP +P
Sbjct: 655 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP---PPPPLP 708



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 30/141 (21%)

Query: 80  GAKVVPP----PGSPDSVVPPPRSPDSV---VPPPGSPDSVVLPPRSP-----DSVVPPP 127
           G   +PP    PGS     PPP  P S     PPP  P    +PP  P       + PPP
Sbjct: 671 GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP 730

Query: 128 GSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187
             P    +PP  P   +PP                 PP       AP     +G  P   
Sbjct: 731 PFPGGPGIPPPPPGMGMPP----------------PPPFGFGVPAAP--VLPFGLTPKKL 772

Query: 188 SPPQVPSRPPSLSQPLSSRVS 208
             P+V  R P+ S+ ++  +S
Sbjct: 773 YKPEVQLRRPNWSKLVAEDLS 793


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 40/120 (33%), Positives = 53/120 (44%), Gaps = 9/120 (7%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSV 143
           PP SP S  PP ++P S+  PP    P     PP SP S  PPP +P  +  PP      
Sbjct: 458 PPVSP-SATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPL--QLA 513

Query: 144 VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPL 203
            PP ++P +          +PPA+   +     +      PLA  PPQ    PP L+ PL
Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA---PPVLAAPL 570



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 45/145 (31%), Positives = 60/145 (41%), Gaps = 20/145 (13%)

Query: 74  STVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPP--GSPDSVVLPPRSPDSVVPPPGSPD 131
           S  L+     +P P       PPP++P ++  PP    P     PP SP    P P +P+
Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP-LATPSPQAPN 429

Query: 132 SVVL--------PPRSPD---SVVPPARSPDSGGRAGSPRSLAPP--AAARAEGAPGWAG 178
           ++ +        PP SP       PPA  P S   + +P S APP  AA   +  P    
Sbjct: 430 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS--PSATPPSQAPPSLAAPPLQVPPSPPA 487

Query: 179 RWGRVPLARSPPQVPSRPPSLSQPL 203
                P A  PPQ P  PP  + PL
Sbjct: 488 SPPMSPSATPPPQAP--PPLAAPPL 510



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 47/163 (28%), Positives = 69/163 (42%), Gaps = 37/163 (22%)

Query: 85  PPPGSPDSV-VPPPRSPDS----------VVPPPGSPDSVVL--------PPRSPDSVVP 125
           PPP +P ++ +PP ++P S            P P +P+++ +        PP SP    P
Sbjct: 392 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451

Query: 126 --PPGSP---DSVVLPPRSPDSV-VPPARSPDS--GGRAGSPRSLAPPAAARAEGAPGWA 177
             PP SP    S   P ++P S+  PP + P S       SP +  PP A     AP   
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--- 508

Query: 178 GRWGRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW 220
                + LA+ PPQ    PP+L+ P    +      FP   P+
Sbjct: 509 ----PLQLAKPPPQA---PPALATPPLQALPSPPASFPGQAPF 544



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 48/162 (29%), Positives = 60/162 (37%), Gaps = 29/162 (17%)

Query: 79  VGAKVVPPPGSPDSVVPPPRS--PDSVVPPPGSPDSVVLPPRSPDSVV--------PPPG 128
           V     PP  +P S+  PP    P     PP SP S   PP++P  +         PPP 
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQLAKPPPQ 518

Query: 129 SPDSVVLP-----PRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRV 183
           +P ++  P     P  P S    A    S     SP +  PP A     AP        +
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LL 571

Query: 184 PLARSPP-----QVPSRPPSLSQPLS-SRVSLYELLFPSWPP 219
            +  SPP     Q P RPP+     S S   L   L P  PP
Sbjct: 572 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 51/156 (32%), Positives = 64/156 (41%), Gaps = 27/156 (17%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDS-----------------VVLPPRSPDSVVPPP 127
           P P +P S   PP S  ++  PP +P S                 +  PP SP    PPP
Sbjct: 337 PLPLAPPSPSAPP-SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP-LATPPP 394

Query: 128 GSPDSVVLPP-RSPDSVVPPARSPDSGGRAGSPRSLAPPA-AARAEGAPGWAGRWGRVPL 185
            +P ++ LPP ++P S  PPA  P S     SP+  AP A A     AP        V  
Sbjct: 395 QAPPALALPPLQAPPS--PPASPPLSPLATPSPQ--APNALAVHLLQAPFSPPPSPPVQA 450

Query: 186 ARSPPQVPSRPPSLSQPLSSRVSLY--ELLFPSWPP 219
             SPP  P   PS + P  +  SL    L  P  PP
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 11/122 (9%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           PP   PD+ V  PR   ++ P P  P     P RSP S +  P           +P+ + 
Sbjct: 589 PPTPGPDTSVSGPRLTLALAPGPPPP-----PSRSPSSTLSGPDLAGHSSSATSTPEEL- 642

Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA-RSPPQVPSRPPSLSQPL 203
              R  DSG   G+  S  PP A  A   P    R    PLA R  P  P   P  + P 
Sbjct: 643 ---RGYDSGPEGGAAAS-PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 698

Query: 204 SS 205
           S+
Sbjct: 699 SA 700



 Score = 28.9 bits (63), Expect = 3.6
 Identities = 32/115 (27%), Positives = 42/115 (36%), Gaps = 17/115 (14%)

Query: 80  GAKVVPPPGSPDSVVPPPRSPDSVVPP------PGSPDSVVLPPRSPDSVVPPPGSPDSV 133
           GA   PPP +  +   P        PP      PG+P  +  PP +       PGS D +
Sbjct: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP--LPWPPAT------GPGSADGL 703

Query: 134 --VLPPRSPDSVVPPARSPDSGGRAG-SPRSLAPPAAARAEGAPGWAGRWGRVPL 185
             +     P+S  P   + D G   G S    A  A A A        R G +PL
Sbjct: 704 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 758


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 40/120 (33%), Positives = 53/120 (44%), Gaps = 9/120 (7%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSV 143
           PP SP S  PP ++P S+  PP    P     PP SP S  PPP +P  +  PP      
Sbjct: 419 PPVSP-SATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPL--QLA 474

Query: 144 VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPL 203
            PP ++P +          +PPA+   +     +      PLA  PPQ    PP L+ PL
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA---PPVLAAPL 531



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 45/145 (31%), Positives = 60/145 (41%), Gaps = 20/145 (13%)

Query: 74  STVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPP--GSPDSVVLPPRSPDSVVPPPGSPD 131
           S  L+     +P P       PPP++P ++  PP    P     PP SP    P P +P+
Sbjct: 332 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP-LATPSPQAPN 390

Query: 132 SVVL--------PPRSPD---SVVPPARSPDSGGRAGSPRSLAPP--AAARAEGAPGWAG 178
           ++ +        PP SP       PPA  P S   + +P S APP  AA   +  P    
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS--PSATPPSQAPPSLAAPPLQVPPSPPA 448

Query: 179 RWGRVPLARSPPQVPSRPPSLSQPL 203
                P A  PPQ P  PP  + PL
Sbjct: 449 SPPMSPSATPPPQAP--PPLAAPPL 471



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 47/163 (28%), Positives = 69/163 (42%), Gaps = 37/163 (22%)

Query: 85  PPPGSPDSV-VPPPRSPDS----------VVPPPGSPDSVVL--------PPRSPDSVVP 125
           PPP +P ++ +PP ++P S            P P +P+++ +        PP SP    P
Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412

Query: 126 --PPGSP---DSVVLPPRSPDSV-VPPARSPDS--GGRAGSPRSLAPPAAARAEGAPGWA 177
             PP SP    S   P ++P S+  PP + P S       SP +  PP A     AP   
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--- 469

Query: 178 GRWGRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW 220
                + LA+ PPQ    PP+L+ P    +      FP   P+
Sbjct: 470 ----PLQLAKPPPQA---PPALATPPLQALPSPPASFPGQAPF 505



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 48/162 (29%), Positives = 60/162 (37%), Gaps = 29/162 (17%)

Query: 79  VGAKVVPPPGSPDSVVPPPRS--PDSVVPPPGSPDSVVLPPRSPDSVV--------PPPG 128
           V     PP  +P S+  PP    P     PP SP S   PP++P  +         PPP 
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQLAKPPPQ 479

Query: 129 SPDSVVLP-----PRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRV 183
           +P ++  P     P  P S    A    S     SP +  PP A     AP        +
Sbjct: 480 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LL 532

Query: 184 PLARSPP-----QVPSRPPSLSQPLS-SRVSLYELLFPSWPP 219
            +  SPP     Q P RPP+     S S   L   L P  PP
Sbjct: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 51/156 (32%), Positives = 64/156 (41%), Gaps = 27/156 (17%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDS-----------------VVLPPRSPDSVVPPP 127
           P P +P S   PP S  ++  PP +P S                 +  PP SP    PPP
Sbjct: 298 PSPSAPPSPSAPP-SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP-LATPPP 355

Query: 128 GSPDSVVLPP-RSPDSVVPPARSPDSGGRAGSPRSLAPPA-AARAEGAPGWAGRWGRVPL 185
            +P ++ LPP ++P S  PPA  P S     SP+  AP A A     AP        V  
Sbjct: 356 QAPPALALPPLQAPPS--PPASPPLSPLATPSPQ--APNALAVHLLQAPFSPPPSPPVQA 411

Query: 186 ARSPPQVPSRPPSLSQPLSSRVSLY--ELLFPSWPP 219
             SPP  P   PS + P  +  SL    L  P  PP
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 447



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 11/122 (9%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           PP   PD+ V  PR   ++ P P  P     P RSP S +  P           +P+ + 
Sbjct: 550 PPTPGPDTSVSGPRLTLALAPGPPPP-----PSRSPSSTLSGPDLAGHSSSATSTPEEL- 603

Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA-RSPPQVPSRPPSLSQPL 203
              R  DSG   G+  S  PP A  A   P    R    PLA R  P  P   P  + P 
Sbjct: 604 ---RGYDSGPEGGAAAS-PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 659

Query: 204 SS 205
           S+
Sbjct: 660 SA 661



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 7/83 (8%)

Query: 95  PPPRSPDSVVP-PPGSPDSVVLPPRSPDS--VVPPPGSPDSVVLPPRSPDSVVPPARSPD 151
           P  R+P  + P PPGSP     PP +P +  V+   G+     L  R+    +  A  P+
Sbjct: 17  PAARAPGLLTPRPPGSPRPP--PPVTPAALRVLGAAGAVGRKPLAERAGG--IGGATIPE 72

Query: 152 SGGRAGSPRSLAPPAAARAEGAP 174
           S  RAG  R+  PPA+ R E AP
Sbjct: 73  SAPRAGPTRTSRPPASGRGERAP 95



 Score = 36.2 bits (82), Expect = 0.023
 Identities = 30/110 (27%), Positives = 39/110 (35%), Gaps = 17/110 (15%)

Query: 100 PDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRA-GS 158
           P  V PP       + P  S     P P +P S   PP       PPA  P     + GS
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332

Query: 159 PR-----------SLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
           P             L+P A    +  P  A     +P  ++PP  P+ PP
Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALA-----LPPLQAPPSPPASPP 377



 Score = 33.1 bits (74), Expect = 0.19
 Identities = 36/129 (27%), Positives = 44/129 (34%), Gaps = 15/129 (11%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP-----PGSPDSVVLPPRSP 140
           P  SP    P  R        P  P    L    P  V PP     P        P  +P
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298

Query: 141 DSVVPPARS-PDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRV------PLARSPPQVP 193
               PP+ S P S     SP +  P  A  + G+P        +      PLA  PPQ  
Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA- 357

Query: 194 SRPPSLSQP 202
             PP+L+ P
Sbjct: 358 --PPALALP 364



 Score = 28.9 bits (63), Expect = 3.6
 Identities = 32/115 (27%), Positives = 42/115 (36%), Gaps = 17/115 (14%)

Query: 80  GAKVVPPPGSPDSVVPPPRSPDSVVPP------PGSPDSVVLPPRSPDSVVPPPGSPDSV 133
           GA   PPP +  +   P        PP      PG+P  +  PP +       PGS D +
Sbjct: 613 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP--LPWPPAT------GPGSADGL 664

Query: 134 --VLPPRSPDSVVPPARSPDSGGRAG-SPRSLAPPAAARAEGAPGWAGRWGRVPL 185
             +     P+S  P   + D G   G S    A  A A A        R G +PL
Sbjct: 665 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 719


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 44/162 (27%), Positives = 58/162 (35%), Gaps = 30/162 (18%)

Query: 60  LFSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRS 119
           L  +   +RV    S   R  A+V PP        PP         P G+P +       
Sbjct: 76  LIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRA-------PRGAPAAAAAAAPP 128

Query: 120 PDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRA-------------------GSPR 160
           P    PPP +P +   P R+P +    A +P S G A                    +P 
Sbjct: 129 PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPP 188

Query: 161 SLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202
           ++APPA  R    P  A R   +P    PP  P  PP   QP
Sbjct: 189 AVAPPAGPRRAPPPAVAAREPPLP----PPPQPPAPPQQQQP 226



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 34/113 (30%), Positives = 50/113 (44%), Gaps = 14/113 (12%)

Query: 94  VPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSG 153
           V PPR   +   PP +P      P +  +  PPP        PP +P +   PAR+P   
Sbjct: 99  VQPPRRGATPPAPPRAPRGA---PAAAAAAAPPPTPAPP---PPPAPVAAAAPARAP--- 149

Query: 154 GRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLSSR 206
            RA +  + APP+   A+  P    R  R     +PP  P+ PP+++ P   R
Sbjct: 150 -RAAAAAATAPPSPGPAQPGP----RAQRAAPLAAPPPAPAAPPAVAPPAGPR 197



 Score = 35.0 bits (79), Expect = 0.050
 Identities = 33/108 (30%), Positives = 44/108 (40%), Gaps = 22/108 (20%)

Query: 85  PPPGSPDSVVPP--PRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           P P +P +V PP  PR      PPP       +  R P   +PPP  P +   PP+    
Sbjct: 182 PAPAAPPAVAPPAGPRR----APPP------AVAAREPP--LPPPPQPPA---PPQQQQP 226

Query: 143 VVPPARSPDSGG---RAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187
             P  + P  GG     G+ R ++     R  G  G AG  GR+   R
Sbjct: 227 PPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAG--GRLTRGR 272


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 44/133 (33%), Positives = 54/133 (40%), Gaps = 9/133 (6%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPP-PGSPDSVVLPPRSPDS 142
           PP S    +PPP  P   +PPP S  P     PP  P+S  PP PG P     PP  P  
Sbjct: 672 PPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGP-----PPAPPPP 726

Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA-RSPPQVPSRPPSLSQ 201
            + P   P      GS  S  P   A     P     W R+ ++ RS    P+   SL +
Sbjct: 727 GLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEE 786

Query: 202 PLSSRVSLYELLF 214
           P     S +E LF
Sbjct: 787 PDIRDPSEFEYLF 799



 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 38/118 (32%), Positives = 44/118 (37%), Gaps = 12/118 (10%)

Query: 82  KVVPPPGSPDSVVPPPRSPD---SVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPR 138
           K +PPP  P S+ PPP  P    S+ P P  P     PP  P    PPP  P S   PP 
Sbjct: 643 KALPPP--PASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPP 700

Query: 139 SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRP 196
            P    PP  +  +    G P    PP        PG         L  S  Q P +P
Sbjct: 701 PPPP--PPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLF-----FGLGSSSSQCPRKP 751


>gi|15529996 son of sevenless homolog 1 [Homo sapiens]
          Length = 1333

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 49/155 (31%), Positives = 61/155 (39%), Gaps = 28/155 (18%)

Query: 84   VPPPGSPDSVVPPPRSPDSVVPPPGSPDSVV---------LPPRSPDSVVPPP----GSP 130
            VPPP      VPP R P+S  P   SP  ++         +PPR P S    P       
Sbjct: 1149 VPPP------VPPRRRPESA-PAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDR 1201

Query: 131  DSVVLPPRSPDSVVP--PARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARS 188
             S+  PP SP  + P  P R+PD    + SP  L PP   +              P    
Sbjct: 1202 TSISDPPESPPLLPPREPVRTPDVF--SSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPP 1259

Query: 189  PPQVPS----RPPSLSQPLSSRVSLYELLFPSWPP 219
            PPQ PS    R    S PL+  V L+ +  P  PP
Sbjct: 1260 PPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPP 1294



 Score = 28.1 bits (61), Expect = 6.1
 Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 49/156 (31%)

Query: 86   PPGSPDSVVPPPRSPDS-VVPPPGSPDS---------------------------VVLP- 116
            P    +S    P SP + + PPP S  S                           V LP 
Sbjct: 1069 PESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPH 1128

Query: 117  -PRSPD-SVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSL------APPA-A 167
             PRS   S +      D V +PP      VPP R P+S     SP  +      +PPA  
Sbjct: 1129 GPRSASVSSISLTKGTDEVPVPPP-----VPPRRRPESAPAESSPSKIMSKHLDSPPAIP 1183

Query: 168  ARAEGAPGWAGRWG---RVPLA---RSPPQVPSRPP 197
             R   +  ++ R+    R  ++    SPP +P R P
Sbjct: 1184 PRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREP 1219


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 37/115 (32%), Positives = 43/115 (37%), Gaps = 16/115 (13%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP--PPGSPDSVVLPPRSPDS 142
           PPPG P    P   +     PPPG P     PP+   S  P  PPG P     PP     
Sbjct: 52  PPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQG---PP----- 101

Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197
             P    P      G  +   PP   + +G P   G   +   ARSPP  P  PP
Sbjct: 102 --PQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG--SKSQSARSPPGKPQGPP 152



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 42/126 (33%), Positives = 50/126 (39%), Gaps = 12/126 (9%)

Query: 85  PPPGSPDSVVPPPRSPDSVVP--PPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           PPPG P    PPP+   S  P  PPG P     PP+      PPP   +    PP     
Sbjct: 72  PPPGKPQG--PPPQGDKSRSPRSPPGKPQGP--PPQGGKPQGPPPQGGNKPQGPPPPGKP 127

Query: 143 VVPPARSPDSGGRAGSP--RSLAPP--AAARAEGAPGWAGRWGRVPLA--RSPPQVPSRP 196
             PPA+       A SP  +   PP       +G P  AG   + P A     PQ P RP
Sbjct: 128 QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 187

Query: 197 PSLSQP 202
           P   +P
Sbjct: 188 PQGGRP 193



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 32/118 (27%), Positives = 41/118 (34%), Gaps = 26/118 (22%)

Query: 88  GSPDSVVPPP-RSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146
           G+P    P     P    PPPG P              PPP   +     P+ P     P
Sbjct: 34  GNPQGPSPQGGNKPQGPPPPPGKPQG------------PPPQGGNK----PQGPPPPGKP 77

Query: 147 ARSPDSGGRAGSPRSL------APPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198
              P  G ++ SPRS        PP   + +G P    + G  P    PP  P  PP+
Sbjct: 78  QGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPP---PQGGNKPQGPPPPGKPQGPPA 132


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 41/122 (33%), Positives = 53/122 (43%), Gaps = 13/122 (10%)

Query: 80  GAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRS 139
           GA   P P  P    PP + P    PPP  P     PP  P    PP   P +  LPP +
Sbjct: 15  GATPAPGPPPPPPPAPPQQQP----PPPPPP----APPPGP-GPAPPQHPPRAEALPPEA 65

Query: 140 PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAP-GWAGRWGRVPLARSPPQVPSRPPS 198
            D   P  R        G P +  P AA+ A+G+P G  GR G    + + P+ P+R P 
Sbjct: 66  ADEGGPRGRLRSRDSSCGRPGT--PGAASTAKGSPNGECGR-GEPQCSPAGPEGPARGPK 122

Query: 199 LS 200
           +S
Sbjct: 123 VS 124



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 37/116 (31%), Positives = 44/116 (37%), Gaps = 8/116 (6%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144
           PPPG      P P +     PPP SP      PR+P    P  G P + +  P  P   +
Sbjct: 761 PPPG------PAPAAASPGPPPPASPPGAPASPRAP-RTSPYGGLPAAPLAGPALPARRL 813

Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLS 200
             A  P S  +   P   AP  AA    A     R G  P AR+    P R  S S
Sbjct: 814 SRASRPLSASQPSLPHG-APGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSAS 868



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 42/155 (27%), Positives = 59/155 (38%), Gaps = 25/155 (16%)

Query: 57  KNALFSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLP 116
           +NA+  ++V     + +   L     + PPP       PPP    S +       ++   
Sbjct: 687 ENAIIQEIVKYDREMVQQAELGQRVGLFPPP-------PPPPQVTSAIATLQQAAAMSFC 739

Query: 117 PRSPDSVVPPP--GSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAP 174
           P+    +V P   GSP  V  PP  P    P A SP      G P   +PP A  +  AP
Sbjct: 740 PQVARPLVGPLALGSPRLVRRPPPGP---APAAASP------GPPPPASPPGAPASPRAP 790

Query: 175 GWAGRWGRVPLARSPPQVP-------SRPPSLSQP 202
             +   G      + P +P       SRP S SQP
Sbjct: 791 RTSPYGGLPAAPLAGPALPARRLSRASRPLSASQP 825


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 42/129 (32%), Positives = 46/129 (35%), Gaps = 16/129 (12%)

Query: 83  VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSP-- 140
           + PPP       PPP+ P    PPP  P     P +      PP  S   VV     P  
Sbjct: 60  IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAP 119

Query: 141 --------DSVVPPARSPDSGGRAGS---PRSLAPPAAARA-EGAPGWAGRWGRVPLARS 188
                    S  PPA  P SG   GS   P    PPA   A  GAP        VP   +
Sbjct: 120 GVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVP--TT 177

Query: 189 PPQVPSRPP 197
           PPQ    PP
Sbjct: 178 PPQAGGPPP 186



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 38/120 (31%), Positives = 41/120 (34%), Gaps = 12/120 (10%)

Query: 88  GSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPA 147
           G    + PPP       PPP  P     PP  P    PP   P     PP  P     P 
Sbjct: 55  GPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP----PPHPQPHQQQQPPPPPQDSSKPV 110

Query: 148 RSPDSG-----GRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202
            +   G     G A    S APPA     GAP  +G     P    PP V S PP    P
Sbjct: 111 VAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG---PTPTPPPAVTSAPPGAPPP 167



 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 41/129 (31%), Positives = 49/129 (37%), Gaps = 11/129 (8%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPPPGS-PDSVVLPPRSPD 141
           PPP   DS  P         P  GS  P S   PP +P +   PPGS P     PP +  
Sbjct: 99  PPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVT 158

Query: 142 SV---VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRP-- 196
           S     PP   P SG     P++  PP    A   PG   + G  P      ++P  P  
Sbjct: 159 SAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP 218

Query: 197 ---PSLSQP 202
              P LS P
Sbjct: 219 GGGPGLSTP 227



 Score = 31.2 bits (69), Expect = 0.73
 Identities = 29/103 (28%), Positives = 33/103 (32%), Gaps = 5/103 (4%)

Query: 85  PPPGSPDSVVP--PPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           PPP  P S VP  PP++     PP   P     P + P    P  G       P   P  
Sbjct: 165 PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGL 224

Query: 143 VVP---PARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGR 182
             P   P      GG     R   PP   +    P   G  GR
Sbjct: 225 STPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGR 267


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 38/123 (30%), Positives = 46/123 (37%), Gaps = 18/123 (14%)

Query: 85  PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVV-----PPPGSPDSVVLPPRS 139
           PPP S     PPP  P +  PPP        PP  P         PPP S  SV +PP  
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPP 338

Query: 140 PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSL 199
           P+ + PP   P     + +P    PP  +            G  P+A  PP  P  PP  
Sbjct: 339 PNRMYPP---PPPALPSSAPSGPPPPPPSVL----------GVGPVAPPPPPPPPPPPGP 385

Query: 200 SQP 202
             P
Sbjct: 386 PPP 388



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 32/94 (34%), Positives = 38/94 (40%), Gaps = 7/94 (7%)

Query: 85  PPPGSPDSVVPPP--RSPDSVVPPPG-SPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPD 141
           PPP       PPP  R+P +  PPP  S  SV +PP  P+ + PPP       LP  +P 
Sbjct: 301 PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPP----ALPSSAPS 356

Query: 142 SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPG 175
              PP  S    G    P    PP        PG
Sbjct: 357 GPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPG 390



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 9/83 (10%)

Query: 80  GAKVVPPPGSPDSVVPPP--RSPDSVVPPPG-----SPDSVVLPPRSPDSVVPPPGSPDS 132
           GA   PP  +P +  PPP    P   VPPP       P    LP  +P    PPP S   
Sbjct: 308 GAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLG 367

Query: 133 V--VLPPRSPDSVVPPARSPDSG 153
           V  V PP  P    PP   P  G
Sbjct: 368 VGPVAPPPPPPPPPPPGPPPPPG 390



 Score = 32.3 bits (72), Expect = 0.33
 Identities = 22/52 (42%), Positives = 22/52 (42%), Gaps = 11/52 (21%)

Query: 85  PPPGSPDSVV----PPPRSPDSVVP--PPGSPDSVVLPPRSPDSVVPPPGSP 130
           PPP  P S      PPP S   V P  PP  P     PP  P    PPPG P
Sbjct: 346 PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP-----PPPPPPGPPPPPGLP 392



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 7/36 (19%)

Query: 75  TVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSP 110
           +VL VG    PPP       PPP  P    PPPG P
Sbjct: 364 SVLGVGPVAPPPP-------PPPPPPPGPPPPPGLP 392


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 39/102 (38%), Positives = 44/102 (43%), Gaps = 14/102 (13%)

Query: 87  PGSPDSVVPPPRSP----DSVVPPPGSPDSVVLPPRSPDSVVPPP----GSPDSVVLPPR 138
           P  PD  +PPP  P    D  +PPP  P   + PP  PD V PPP    G   S + PP 
Sbjct: 547 PAPPDDFLPPPPPPPPLDDPELPPP--PPDFMEPP--PDFVPPPPPSYAGIAGSELPPPP 602

Query: 139 SPDSVVPPARSPDSG--GRAGSPRSLAPPAAARAEGAPGWAG 178
            P     PA  PDS     A + R   PP      G PG AG
Sbjct: 603 PPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAG 644



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 43/128 (33%), Positives = 49/128 (38%), Gaps = 25/128 (19%)

Query: 87  PGSPDSVVPPPRSPDSVVPPPGSPDSVVLP--------PRSPDSVVPPPGSP---DSVVL 135
           P +P S +PPP          GSP + +          P  PD  +PPP  P   D   L
Sbjct: 509 PHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPEL 568

Query: 136 PPRSPDSVVP-----PARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVP-LARSP 189
           PP  PD + P     P   P   G AGS     PP       AP        VP  AR P
Sbjct: 569 PPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAP--------VPDSARPP 620

Query: 190 PQVPSRPP 197
           P V  RPP
Sbjct: 621 PAVAKRPP 628



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 30/78 (38%), Positives = 35/78 (44%), Gaps = 8/78 (10%)

Query: 86  PPGSPDSVVPPPRSPDSVVPPPGSPDSVV---LPPRSPDSVVPPPGS-PDSVVLPPR-SP 140
           PP  PD + PPP   D V PPP S   +    LPP  P    P P   PDS   PP  + 
Sbjct: 569 PPPPPDFMEPPP---DFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAK 625

Query: 141 DSVVPPARSPDSGGRAGS 158
              VPP R  + G   G+
Sbjct: 626 RPPVPPKRQENPGHPGGA 643



 Score = 34.7 bits (78), Expect = 0.066
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 1/50 (2%)

Query: 80  GAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGS 129
           G+++ PPP  P +  P P  PDS  PPP       +PP+  ++   P G+
Sbjct: 595 GSELPPPPPPPPAPAPAP-VPDSARPPPAVAKRPPVPPKRQENPGHPGGA 643



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 9/72 (12%)

Query: 83  VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142
           V PPP S   +        S +PPP  P     P   PDS  PPP       +PP+  ++
Sbjct: 583 VPPPPPSYAGIA------GSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQEN 636

Query: 143 VVPPARSPDSGG 154
              P     +GG
Sbjct: 637 ---PGHPGGAGG 645


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,264,552
Number of Sequences: 37866
Number of extensions: 938414
Number of successful extensions: 18336
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 466
Number of HSP's successfully gapped in prelim test: 1344
Number of HSP's that attempted gapping in prelim test: 6563
Number of HSP's gapped (non-prelim): 6917
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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