BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239752263 PREDICTED: hypothetical protein XP_002348185 [Homo sapiens] (220 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239752263 PREDICTED: hypothetical protein XP_002348185 [Homo ... 459 e-130 gi|239746776 PREDICTED: hypothetical protein XP_002343846 [Homo ... 294 5e-80 gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo ... 287 6e-78 gi|239757968 PREDICTED: hypothetical protein [Homo sapiens] 162 3e-40 gi|239747023 PREDICTED: hypothetical protein XP_002343907 [Homo ... 162 3e-40 gi|239747021 PREDICTED: hypothetical protein XP_002343906 [Homo ... 162 3e-40 gi|150170670 piccolo isoform 2 [Homo sapiens] 66 2e-11 gi|150378539 piccolo isoform 1 [Homo sapiens] 66 2e-11 gi|146134388 YLP motif containing 1 [Homo sapiens] 64 1e-10 gi|27436925 synoviolin 1 isoform a [Homo sapiens] 59 2e-09 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 3e-09 gi|110832843 TBP-associated factor 4 [Homo sapiens] 58 6e-09 gi|27436927 synoviolin 1 isoform b [Homo sapiens] 58 7e-09 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 56 3e-08 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 56 3e-08 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 55 4e-08 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 55 5e-08 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 55 5e-08 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 54 1e-07 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 54 1e-07 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 53 2e-07 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 53 2e-07 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 53 2e-07 gi|157168329 formin 1 [Homo sapiens] 52 3e-07 gi|15529996 son of sevenless homolog 1 [Homo sapiens] 52 3e-07 gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 52 3e-07 gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 52 4e-07 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 52 5e-07 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 51 7e-07 gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 51 7e-07 >gi|239752263 PREDICTED: hypothetical protein XP_002348185 [Homo sapiens] Length = 220 Score = 459 bits (1182), Expect = e-130 Identities = 220/220 (100%), Positives = 220/220 (100%) Query: 1 MLISVSQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNAL 60 MLISVSQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNAL Sbjct: 1 MLISVSQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNAL 60 Query: 61 FSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSP 120 FSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSP Sbjct: 61 FSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSP 120 Query: 121 DSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRW 180 DSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRW Sbjct: 121 DSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRW 180 Query: 181 GRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW 220 GRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW Sbjct: 181 GRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW 220 >gi|239746776 PREDICTED: hypothetical protein XP_002343846 [Homo sapiens] Length = 210 Score = 294 bits (752), Expect = 5e-80 Identities = 138/138 (100%), Positives = 138/138 (100%) Query: 83 VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS Sbjct: 73 VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 132 Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP Sbjct: 133 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 192 Query: 203 LSSRVSLYELLFPSWPPW 220 LSSRVSLYELLFPSWPPW Sbjct: 193 LSSRVSLYELLFPSWPPW 210 >gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo sapiens] Length = 225 Score = 287 bits (734), Expect = 6e-78 Identities = 136/138 (98%), Positives = 136/138 (98%) Query: 83 VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 VV PP SPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS Sbjct: 88 VVLPPRSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 147 Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP Sbjct: 148 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 207 Query: 203 LSSRVSLYELLFPSWPPW 220 LSSRVSLYELLFPSWPPW Sbjct: 208 LSSRVSLYELLFPSWPPW 225 Score = 126 bits (316), Expect = 2e-29 Identities = 76/124 (61%), Positives = 79/124 (63%), Gaps = 4/124 (3%) Query: 83 VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 VV P SPDSVV P RSPDSVV PPGSPDSVVLP RSPDSVVPPPGSPDSVVLPPRSPDS Sbjct: 18 VVLPSRSPDSVVLPSRSPDSVVLPPGSPDSVVLPSRSPDSVVPPPGSPDSVVLPPRSPDS 77 Query: 143 VVPPARSPDSGG-RAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQV---PSRPPS 198 VVPP SPDS SP S+ PP + P V RSP V P P S Sbjct: 78 VVPPPGSPDSVVLPPRSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDS 137 Query: 199 LSQP 202 + P Sbjct: 138 VVLP 141 Score = 90.1 bits (222), Expect = 1e-18 Identities = 62/117 (52%), Positives = 65/117 (55%), Gaps = 4/117 (3%) Query: 90 PDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARS 149 P SV S SVV P SPDSVVLP RSPDSVV PPGSPDSVVLP RSPDSVVPP S Sbjct: 5 PVSVGSTWPSTHSVVLPSRSPDSVVLPSRSPDSVVLPPGSPDSVVLPSRSPDSVVPPPGS 64 Query: 150 PDSGG-RAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQV---PSRPPSLSQP 202 PDS SP S+ PP + VP RSP V P P S+ P Sbjct: 65 PDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPRSPDSVVPPPGSPDSVVLP 121 >gi|239757968 PREDICTED: hypothetical protein [Homo sapiens] Length = 157 Score = 162 bits (409), Expect = 3e-40 Identities = 77/82 (93%), Positives = 79/82 (96%) Query: 139 SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198 +P SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS Sbjct: 3 APYSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 62 Query: 199 LSQPLSSRVSLYELLFPSWPPW 220 LSQPLSSRVSL+ELL PS PPW Sbjct: 63 LSQPLSSRVSLHELLLPSRPPW 84 >gi|239747023 PREDICTED: hypothetical protein XP_002343907 [Homo sapiens] Length = 157 Score = 162 bits (409), Expect = 3e-40 Identities = 77/82 (93%), Positives = 79/82 (96%) Query: 139 SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198 +P SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS Sbjct: 3 APYSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 62 Query: 199 LSQPLSSRVSLYELLFPSWPPW 220 LSQPLSSRVSL+ELL PS PPW Sbjct: 63 LSQPLSSRVSLHELLLPSRPPW 84 >gi|239747021 PREDICTED: hypothetical protein XP_002343906 [Homo sapiens] Length = 157 Score = 162 bits (409), Expect = 3e-40 Identities = 77/82 (93%), Positives = 79/82 (96%) Query: 139 SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198 +P SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS Sbjct: 3 APYSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 62 Query: 199 LSQPLSSRVSLYELLFPSWPPW 220 LSQPLSSRVSL+ELL PS PPW Sbjct: 63 LSQPLSSRVSLHELLLPSRPPW 84 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 66.2 bits (160), Expect = 2e-11 Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 7/120 (5%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 PP P PPP+ P PPP P S P + P S PPP P P+ P S Sbjct: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528 Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLS 204 PP++ P S + S A P+A ++ G + P Q P+ PS QP S Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-------SGKPLQPPTVSPSAKQPPS 581 Score = 42.4 bits (98), Expect = 3e-04 Identities = 35/121 (28%), Positives = 44/121 (36%), Gaps = 7/121 (5%) Query: 85 PPPGSPDSVVPP-PRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSV 143 P PG P + P +S PP P + P V PP P PP P Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--- 365 Query: 144 VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP--QVPSRPPSLSQ 201 + PA+ P + P S P A A+ PG + P PP QV + P Q Sbjct: 366 LGPAKPPAQQTGSEKPSSEQPGPKALAQ-PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424 Query: 202 P 202 P Sbjct: 425 P 425 Score = 41.6 bits (96), Expect = 5e-04 Identities = 46/177 (25%), Positives = 70/177 (39%), Gaps = 30/177 (16%) Query: 27 PSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPP 86 P ++ L T+ F ++ + P + LP ++ S R +S+ L + A+ PP Sbjct: 2351 PMKEQLSTTY-FTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF-RSSSLDISAQPPPP 2408 Query: 87 PGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146 P P PPP PPP PP P +PPP SP +LP + P Sbjct: 2409 PPPP----PPP-------PPP--------PPPPPPPPLPPPTSPKPTILPKKKLTVASPV 2449 Query: 147 ARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPL 203 + + +L A R+ G P R+ +PP VP +P S+ L Sbjct: 2450 TTATP---LFDAVTTLETTAVLRSNGLP-----VTRI-CTTAPPPVPPKPSSIPSGL 2497 Score = 37.7 bits (86), Expect = 0.008 Identities = 34/143 (23%), Positives = 49/143 (34%), Gaps = 32/143 (22%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPG-------------SPDS 132 PP P + P V PP P PP P PP P + Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390 Query: 133 VVLPP---RSPDSVVPPARSPDSGGRAGSPRSLA-------PPAAARAEGAPGWAGRWGR 182 + PP ++P PA+ P + G+P+ LA P A P G+ Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQ--QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448 Query: 183 VPLARSPP-------QVPSRPPS 198 +P ++ P P++PPS Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPS 471 Score = 37.7 bits (86), Expect = 0.008 Identities = 39/147 (26%), Positives = 54/147 (36%), Gaps = 12/147 (8%) Query: 71 LCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSP 130 L + L+ AK P +P P + P P G + P P S +P P P Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKP 479 Query: 131 DSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP 190 PP+ P PA+ P + P S P + PG A + P + PP Sbjct: 480 -----PPQQPG----PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530 Query: 191 --QVPSRPPSLSQPLSSRVSLYELLFP 215 Q S PS QP ++ S + P Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Score = 33.9 bits (76), Expect = 0.11 Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 8/80 (10%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 P P P S PP + P S P P + V GS P P +V Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG-----KPLQPPTVS 573 Query: 145 PPARSPDSGGRAGSPRSLAP 164 P A+ P S G P+++ P Sbjct: 574 PSAKQPPS---QGLPKTICP 590 Score = 28.5 bits (62), Expect = 4.7 Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Query: 89 SPDSVVPPPRSPDSVVPPPGSPDSVVLPPRS---PDSVVPPPGSPDSVVLPPRSPDSVVP 145 SP S + P ++ +S P P + P+ PD PP SP + + RS P Sbjct: 3625 SPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684 Query: 146 PARSPDSGGRA 156 + + D RA Sbjct: 3685 LSPTADESSRA 3695 Score = 28.1 bits (61), Expect = 6.1 Identities = 23/116 (19%), Positives = 38/116 (32%), Gaps = 7/116 (6%) Query: 82 KVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPD 141 K P P P + PP+S P P V ++P + P + + + + Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024 Query: 142 SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 PP + DS P+ P P PL ++ + S+ P Sbjct: 1025 KKPPPIK--DSKSLTAEPQKAVLPTKLEKSPKPE-----STCPLCKTELNIGSKDP 1073 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 66.2 bits (160), Expect = 2e-11 Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 7/120 (5%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 PP P PPP+ P PPP P S P + P S PPP P P+ P S Sbjct: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528 Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLS 204 PP++ P S + S A P+A ++ G + P Q P+ PS QP S Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-------SGKPLQPPTVSPSAKQPPS 581 Score = 42.4 bits (98), Expect = 3e-04 Identities = 35/121 (28%), Positives = 44/121 (36%), Gaps = 7/121 (5%) Query: 85 PPPGSPDSVVPP-PRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSV 143 P PG P + P +S PP P + P V PP P PP P Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--- 365 Query: 144 VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP--QVPSRPPSLSQ 201 + PA+ P + P S P A A+ PG + P PP QV + P Q Sbjct: 366 LGPAKPPAQQTGSEKPSSEQPGPKALAQ-PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424 Query: 202 P 202 P Sbjct: 425 P 425 Score = 41.6 bits (96), Expect = 5e-04 Identities = 46/177 (25%), Positives = 70/177 (39%), Gaps = 30/177 (16%) Query: 27 PSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPP 86 P ++ L T+ F ++ + P + LP ++ S R +S+ L + A+ PP Sbjct: 2351 PMKEQLSTTY-FTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF-RSSSLDISAQPPPP 2408 Query: 87 PGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146 P P PPP PPP PP P +PPP SP +LP + P Sbjct: 2409 PPPP----PPP-------PPP--------PPPPPPPPLPPPTSPKPTILPKKKLTVASPV 2449 Query: 147 ARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPL 203 + + +L A R+ G P R+ +PP VP +P S+ L Sbjct: 2450 TTATP---LFDAVTTLETTAVLRSNGLP-----VTRI-CTTAPPPVPPKPSSIPSGL 2497 Score = 37.7 bits (86), Expect = 0.008 Identities = 34/143 (23%), Positives = 49/143 (34%), Gaps = 32/143 (22%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPG-------------SPDS 132 PP P + P V PP P PP P PP P + Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390 Query: 133 VVLPP---RSPDSVVPPARSPDSGGRAGSPRSLA-------PPAAARAEGAPGWAGRWGR 182 + PP ++P PA+ P + G+P+ LA P A P G+ Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQ--QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448 Query: 183 VPLARSPP-------QVPSRPPS 198 +P ++ P P++PPS Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPS 471 Score = 37.7 bits (86), Expect = 0.008 Identities = 39/147 (26%), Positives = 54/147 (36%), Gaps = 12/147 (8%) Query: 71 LCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSP 130 L + L+ AK P +P P + P P G + P P S +P P P Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKP 479 Query: 131 DSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP 190 PP+ P PA+ P + P S P + PG A + P + PP Sbjct: 480 -----PPQQPG----PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530 Query: 191 --QVPSRPPSLSQPLSSRVSLYELLFP 215 Q S PS QP ++ S + P Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Score = 33.9 bits (76), Expect = 0.11 Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 8/80 (10%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 P P P S PP + P S P P + V GS P P +V Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG-----KPLQPPTVS 573 Query: 145 PPARSPDSGGRAGSPRSLAP 164 P A+ P S G P+++ P Sbjct: 574 PSAKQPPS---QGLPKTICP 590 Score = 28.5 bits (62), Expect = 4.7 Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Query: 89 SPDSVVPPPRSPDSVVPPPGSPDSVVLPPRS---PDSVVPPPGSPDSVVLPPRSPDSVVP 145 SP S + P ++ +S P P + P+ PD PP SP + + RS P Sbjct: 3625 SPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684 Query: 146 PARSPDSGGRA 156 + + D RA Sbjct: 3685 LSPTADESSRA 3695 Score = 28.1 bits (61), Expect = 6.1 Identities = 23/116 (19%), Positives = 38/116 (32%), Gaps = 7/116 (6%) Query: 82 KVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPD 141 K P P P + PP+S P P V ++P + P + + + + Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024 Query: 142 SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 PP + DS P+ P P PL ++ + S+ P Sbjct: 1025 KKPPPIK--DSKSLTAEPQKAVLPTKLEKSPKPE-----STCPLCKTELNIGSKDP 1073 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 63.9 bits (154), Expect = 1e-10 Identities = 53/144 (36%), Positives = 65/144 (45%), Gaps = 27/144 (18%) Query: 79 VGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSV---VLPPRSPDSVVPPPGSPDSVVL 135 +G +PPP P S +PPP +PPP P S+ V+PP P + VPPPG P V + Sbjct: 511 MGNMSMPPPFVPYSQMPPPLP---TMPPPVLPPSLPPPVMPPALP-ATVPPPGMPPPV-M 565 Query: 136 PPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSR 195 PP P SV PP P S AG P L PP+ + A PP +P Sbjct: 566 PPSLPTSVPPPGMPP-SLSSAGPPPVLPPPSLSS----------------AGPPPVLP-- 606 Query: 196 PPSLSQPLSSRVSLYELLFPSWPP 219 PPSLS V L + PP Sbjct: 607 PPSLSSTAPPPVMPLPPLSSATPP 630 Score = 56.2 bits (134), Expect = 2e-08 Identities = 48/141 (34%), Positives = 54/141 (38%), Gaps = 30/141 (21%) Query: 84 VPPPGSPDSVVPPPRSPDSVVPPPGSPDSV---------------------VLPPRSPDS 122 VPPPG P V+PP S + VPPPG P S+ VLPP S S Sbjct: 555 VPPPGMPPPVMPP--SLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSS 612 Query: 123 VVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSL-APPAAARAEGAPGWAGRWG 181 PPP P LPP S S PP P G G P L A P + Sbjct: 613 TAPPPVMP----LPPLS--SATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKP 666 Query: 182 RVPLARSPPQVPSRPPSLSQP 202 R L +P S PP+ P Sbjct: 667 RPALLPTPVSFGSAPPTTYHP 687 Score = 51.2 bits (121), Expect = 7e-07 Identities = 46/143 (32%), Positives = 56/143 (39%), Gaps = 25/143 (17%) Query: 80 GAKVVPPPGSPDSVVPPPRSP----DSVVPPPGSPDSVVLPPRS---PDSVVPPPGSPDS 132 G V PP S S PPP P S PPP P LPP S P +PPPG P Sbjct: 586 GPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP----LPPLSSATPPPGIPPPGVPQG 641 Query: 133 VVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQV 192 + PP+ + VPPA S S PR P AP P PP Sbjct: 642 I--PPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAP---------PTTYHPPLQ 690 Query: 193 PSRPPSLSQPLSSRVSLYELLFP 215 + P S+ ++S+ L + P Sbjct: 691 SAGP---SEQVNSKAPLSKSALP 710 Score = 38.9 bits (89), Expect = 0.003 Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 PPPGS P + P S+V P P +P P +PPP P LPP P V+ Sbjct: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPP--LPP--PPPVI 1562 Query: 145 PPARS 149 P S Sbjct: 1563 KPQTS 1567 Score = 37.0 bits (84), Expect = 0.013 Identities = 48/174 (27%), Positives = 63/174 (36%), Gaps = 46/174 (26%) Query: 85 PPPGSPDSVVP--------PPRSPDSVVPPPGS--------------------------P 110 PPP P V+P PP P + PPPG P Sbjct: 83 PPPLPPPPVMPGGGYGDWQPP--PPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP 140 Query: 111 DSVVLPPRSPDSVVPPPGS----PDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPA 166 + PP SP PPGS S + PP+ P S PP S A S +PP+ Sbjct: 141 MELESPPESPP---VPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPS 197 Query: 167 AARAEGAPGW--AGRWGRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWP 218 + P + + + L+ S +PS S S+P S S +LL P P Sbjct: 198 QSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRP-SQGHSKSQLLAPPPP 250 Score = 36.6 bits (83), Expect = 0.017 Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 6/122 (4%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP 145 PP P S +PP +S +PPP P S PP S +PP S P +S + P Sbjct: 150 PPVPPGSYMPPSQS---YMPPPQPPPSYY-PPTSSQPYLPPAQPSPSQSPPSQSYLAPTP 205 Query: 146 PARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVP--SRPPSLSQPL 203 S S ++ S + +++A + G LA PP P ++ +PL Sbjct: 206 SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPL 265 Query: 204 SS 205 S Sbjct: 266 ES 267 Score = 32.0 bits (71), Expect = 0.43 Identities = 28/85 (32%), Positives = 32/85 (37%), Gaps = 21/85 (24%) Query: 55 WSKNALFSKVVFIRVHL---------CKSTVLRVGAKVVPP-----PGSPDSVVPPPRSP 100 W + L S +VHL K T V +V P P SP S PP P Sbjct: 297 WYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPP 356 Query: 101 DSVVPPPGSPDSVVLPPRSPDSVVP 125 + VPPP LPP P S P Sbjct: 357 NEEVPPP-------LPPEEPQSEDP 374 Score = 31.6 bits (70), Expect = 0.56 Identities = 32/117 (27%), Positives = 44/117 (37%), Gaps = 13/117 (11%) Query: 90 PDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARS 149 P + PPP P V+P G D PP P PPPG S + ++ R Sbjct: 78 PHHLPPPPLPPPPVMPGGGYGDWQPPPPPMP----PPPGPALSYQKQQQYKHQMLHHQRD 133 Query: 150 PDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLSSR 206 G P + + E P G + +P ++S P PPS P SS+ Sbjct: 134 -------GPPGLVPMELESPPESPPVPPGSY--MPPSQSYMPPPQPPPSYYPPTSSQ 181 Score = 30.0 bits (66), Expect = 1.6 Identities = 28/94 (29%), Positives = 37/94 (39%), Gaps = 8/94 (8%) Query: 84 VPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPP---GSPDSVVLPPRSP 140 +PPP P S PP S + PP P PP S + P P S S Sbjct: 165 MPPPQPPPSYYPPTSSQPYL--PPAQPSPSQSPP-SQSYLAPTPSYSSSSSSSQSYLSHS 221 Query: 141 DSVVPPARSPDSGGRAGSPRS--LAPPAAARAEG 172 S +P +++ S G +S LAPP + G Sbjct: 222 QSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPG 255 Score = 28.9 bits (63), Expect = 3.6 Identities = 32/163 (19%), Positives = 58/163 (35%), Gaps = 22/163 (13%) Query: 10 ISNECQWHLNQLSDHTEPSE--------QHLPGTHAFAEVQSRSSKFPTN-------TLP 54 + + W +LSD PS+ +H+P +H +E+ + ++ L Sbjct: 1390 VPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLS 1449 Query: 55 WSKNALFSKVVF-IRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPR------SPDSVVPPP 107 ++ + K +++ + L+ P D + P S + PPP Sbjct: 1450 QRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPP 1509 Query: 108 GSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSP 150 GS + P S+V P P +P P +PP P Sbjct: 1510 GSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP 1552 Score = 28.5 bits (62), Expect = 4.7 Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 1/30 (3%) Query: 110 PDSVVLPPRSPDSVVPPPGSPDSVVLPPRS 139 P + VLPP S +PPPG P + +PP S Sbjct: 1603 PSAPVLPPPPVHSSIPPPG-PVPMGMPPMS 1631 Score = 27.7 bits (60), Expect = 8.0 Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 5/38 (13%) Query: 90 PDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPP 127 P + V PP S +PPPG P + +PP S PPP Sbjct: 1603 PSAPVLPPPPVHSSIPPPG-PVPMGMPPMSK----PPP 1635 >gi|27436925 synoviolin 1 isoform a [Homo sapiens] Length = 616 Score = 59.3 bits (142), Expect = 2e-09 Identities = 43/136 (31%), Positives = 58/136 (42%), Gaps = 4/136 (2%) Query: 72 CKSTVLRVG--AKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDS--VVPPP 127 C+ VLR A+ PPP D PP P ++P P + +LPP P + PP Sbjct: 329 CRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPM 388 Query: 128 GSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187 G V PP S ++V PP+ S +G+ + A +A A A G P A Sbjct: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 448 Query: 188 SPPQVPSRPPSLSQPL 203 P P PP + PL Sbjct: 449 PAPGFPFPPPWMGMPL 464 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 58.9 bits (141), Expect = 3e-09 Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 10/138 (7%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPPPGSPDSVVLPP-RSPDS 142 PP SP S PP ++P S+ PP P PP SP S PPP +P + PP + P S Sbjct: 683 PPVSP-SATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQVPPS 740 Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202 PPA P S PR AA + P PLA+ PPQ PP+L+ P Sbjct: 741 --PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA---PPALATP 795 Query: 203 LSSRVSLYELLFPSWPPW 220 + FP P+ Sbjct: 796 PLQALPSPPASFPGQAPF 813 Score = 50.1 bits (118), Expect = 2e-06 Identities = 49/135 (36%), Positives = 56/135 (41%), Gaps = 26/135 (19%) Query: 86 PPGSPDSVVPPPRSPDSVVPPP--GSPDSVVLPPRSPDSVVPPPGSPDSVVLPP-RSPDS 142 PP SP + PPP++P + PP P PP SP S PPP P + PP + P S Sbjct: 714 PPMSPSA-TPPPQAPPPLAAPPLQVPPSPPASPPMSP-SATPPPRVPPLLAAPPLQVPPS 771 Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAAR---------AEGAPGWA-----GRWGRVPLARS 188 PPA P S P APPA A PG A PLA Sbjct: 772 --PPASLPMS--PLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827 Query: 189 PPQVPSRPPSLSQPL 203 PPQ PP L+ PL Sbjct: 828 PPQA---PPVLAAPL 839 Score = 47.8 bits (112), Expect = 7e-06 Identities = 42/131 (32%), Positives = 54/131 (41%), Gaps = 17/131 (12%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVL--------PP 137 PP SP + PP P +PP +P S P P P +P+++ + PP Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668 Query: 138 RSPD---SVVPPARSPDSGGRAGSPRSLAPP--AAARAEGAPGWAGRWGRVPLARSPPQV 192 SP PPA P S + +P S APP AA + P P A PPQ Sbjct: 669 PSPPVQAPFSPPASPPVS--PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726 Query: 193 PSRPPSLSQPL 203 P PP + PL Sbjct: 727 P--PPLAAPPL 735 Score = 46.6 bits (109), Expect = 2e-05 Identities = 44/143 (30%), Positives = 58/143 (40%), Gaps = 13/143 (9%) Query: 87 PGSPDSVVPPPRSPDSVV-PPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP 145 P SP PPP +P S+ PPP +P ++ PP + PP SP + P P +P Sbjct: 572 PPSP-LTTPPPETPSSIATPPPQAPPALASPPLQ--GLPSPPLSPLATPPPQAPPXLALP 628 Query: 146 PARSPDSGGRAGSPRSLAPPA-------AARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198 P ++P S + LA P+ A AP V SPP P PS Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688 Query: 199 LSQPLSSRVSLY--ELLFPSWPP 219 + P + SL L P PP Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPP 711 Score = 46.2 bits (108), Expect = 2e-05 Identities = 44/142 (30%), Positives = 59/142 (41%), Gaps = 33/142 (23%) Query: 85 PPPGSPDSVVPPPRSPDS----------VVPPPGSPDSVVL--------PPRSPDSVVP- 125 PP P +PP ++P S P P +P+++ + PP SP P Sbjct: 618 PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677 Query: 126 -PPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAP--PAAARAEGAPGWAGRWGR 182 PP SP V P +P S PP+ + SP + P P+A AP Sbjct: 678 SPPASPP--VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP-------- 727 Query: 183 VPLARSPPQVPSRPPSLSQPLS 204 PLA P QVP PP+ S P+S Sbjct: 728 PPLAAPPLQVPPSPPA-SPPMS 748 Score = 45.8 bits (107), Expect = 3e-05 Identities = 51/164 (31%), Positives = 73/164 (44%), Gaps = 34/164 (20%) Query: 81 AKVVPPPGSPDSVVPP--PRSPDSVVPPPGSPDSVVLPPR-----SPDSVVPPPGSPDSV 133 A+ VPPP + + +P P SP P P +P S PP SP + PP +P S+ Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA-TPPSQAPPSM 372 Query: 134 VLPP-RSPDSV--VPPARSPDSGGRAGSPRSLAPPA--------AARAEGAPGWAGRWGR 182 PP ++P S+ +PP + P S SP APP+ A + G+P Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHS---LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429 Query: 183 VPLARSPPQV----PSRP---PSLSQPLSSRVSLYELLFPSWPP 219 + ++ Q PSRP P S PL + +SL P+ PP Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL-----PASPP 468 Score = 45.1 bits (105), Expect = 5e-05 Identities = 46/127 (36%), Positives = 57/127 (44%), Gaps = 22/127 (17%) Query: 86 PPGSPDSVVP--PPRSPD---SVVPPPGSPDSVVLPP-RSPDSVVPPPGSPDSVVLPPRS 139 PP SP P PP SP S PP +P S+ PP + P S PP SP + P + Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS---PPASPP--MSPSAT 721 Query: 140 PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVP--LARSPPQVPSRPP 197 P PP + SP + +PP + A P RVP LA P QVP PP Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPA-SPPMSPSATPPP-------RVPPLLAAPPLQVPPSPP 773 Query: 198 SLSQPLS 204 + S P+S Sbjct: 774 A-SLPMS 779 Score = 42.4 bits (98), Expect = 3e-04 Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 22/122 (18%) Query: 85 PPPGSPDSVVPPP--------RSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLP 136 PP + S+ PPP +P PP +P + PP SP PPP +P S+ P Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP-SP-LTTPPPETPSSIATP 590 Query: 137 P-RSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSR 195 P ++P ++ SP G P L+P A + P A +P ++PP P+ Sbjct: 591 PPQAPPALA----SPPLQGLPSPP--LSPLATPPPQAPPXLA-----LPPLQAPPSPPAS 639 Query: 196 PP 197 PP Sbjct: 640 PP 641 Score = 41.6 bits (96), Expect = 5e-04 Identities = 45/151 (29%), Positives = 58/151 (38%), Gaps = 26/151 (17%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSV------VPPPGSPDSVVLP--- 136 PP SP + P +P VPP + + +PP P S+ PPP +P ++ P Sbjct: 741 PPASPP--MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798 Query: 137 --PRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPP---- 190 P P S A S SP + PP A AP + + SPP Sbjct: 799 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LLQVPPSPPASPT 851 Query: 191 -QVPSRPPSLSQPLS-SRVSLYELLFPSWPP 219 Q P RPP+ S S L L P PP Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882 Score = 38.5 bits (88), Expect = 0.005 Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 11/122 (9%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 PP PD+ V PR ++ P P P P RSP S + P +P+ + Sbjct: 858 PPTPGPDTSVSGPRLTLALAPGPPPP-----PSRSPSSTLSGPDLAGHSSSATSTPEEL- 911 Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA-RSPPQVPSRPPSLSQPL 203 R DSG G+ S PP A A P R PLA R P P P + P Sbjct: 912 ---RGYDSGPEGGAAAS-PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 967 Query: 204 SS 205 S+ Sbjct: 968 SA 969 Score = 34.7 bits (78), Expect = 0.066 Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 13/117 (11%) Query: 82 KVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPD 141 +V PP + P S P P + +PP PD+ +P LPP SP Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP--PDNA----ATPLPATLPP-SPP 336 Query: 142 SVVPPARSPDSGGRAGSPRSL-APPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 P +P S S ++L +PPA ++ P P ++PP + + PP Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT-----TPPMQAPPSLQTIPP 388 Score = 33.1 bits (74), Expect = 0.19 Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 14/103 (13%) Query: 100 PDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSP 159 P V PP + P S P P + +PP + PA P S A +P Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA-TP 340 Query: 160 RSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202 LAPP+ + AP P ++ P P+ PPS + P Sbjct: 341 LPLAPPSPS----AP---------PSLQTLPSPPATPPSQAPP 370 Score = 28.9 bits (63), Expect = 3.6 Identities = 32/115 (27%), Positives = 42/115 (36%), Gaps = 17/115 (14%) Query: 80 GAKVVPPPGSPDSVVPPPRSPDSVVPP------PGSPDSVVLPPRSPDSVVPPPGSPDSV 133 GA PPP + + P PP PG+P + PP + PGS D + Sbjct: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP--LPWPPAT------GPGSADGL 972 Query: 134 --VLPPRSPDSVVPPARSPDSGGRAG-SPRSLAPPAAARAEGAPGWAGRWGRVPL 185 + P+S P + D G G S A A A A R G +PL Sbjct: 973 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 1027 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 58.2 bits (139), Expect = 6e-09 Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 27/176 (15%) Query: 36 HAFAEVQSRSSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVP 95 HA A S + P LP K A V+ T VGA P P +P Sbjct: 209 HAAAPAVSLVNNGPAALLPLPKPAAPGTVI--------QTPPFVGAAAPPAPAAPSPPAA 260 Query: 96 PPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGR 155 P + + PPP PP +P ++ PPG P PP + +V PPA + +GG Sbjct: 261 PAPAAPAAAPPP--------PPPAPATLARPPGHPAG---PPTAAPAVPPPA-AAQNGGS 308 Query: 156 AGSPRSLAPPAA--ARAEGAPGWAGRWGRVPL----ARSPPQVPSRPPSLSQPLSS 205 AG+ + AP A A G PG G P A SP +V P +Q L++ Sbjct: 309 AGAAPAPAPAAGGPAGVSGQPG-PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA 363 Score = 30.4 bits (67), Expect = 1.2 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 5/73 (6%) Query: 135 LPPRSPDSVVPPARSPDSGGRAGSPRSLAPPA-AARAEGAPGWAGR---WGRVPLARSPP 190 L PR+P+ A + + +GSP A AA AEGAPG A GR P Sbjct: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102 Query: 191 QVPSRPPSLSQPL 203 Q P PPS +PL Sbjct: 103 QRPG-PPSPRRPL 114 >gi|27436927 synoviolin 1 isoform b [Homo sapiens] Length = 617 Score = 57.8 bits (138), Expect = 7e-09 Identities = 44/137 (32%), Positives = 60/137 (43%), Gaps = 5/137 (3%) Query: 72 CKSTVLRVG--AKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPD--SVVPPP 127 C+ VLR A+ PPP D PP P ++P P + +LPP P + PP Sbjct: 329 CRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPM 388 Query: 128 GSPDSVVLPPRSPDSVVPPARSPDSGGR-AGSPRSLAPPAAARAEGAPGWAGRWGRVPLA 186 G V PP S ++V PP+ S + R +G+ + A +A A A G P A Sbjct: 389 GPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEA 448 Query: 187 RSPPQVPSRPPSLSQPL 203 P P PP + PL Sbjct: 449 GPAPGFPFPPPWMGMPL 465 Score = 43.5 bits (101), Expect = 1e-04 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 4/112 (3%) Query: 86 PPGSPDSVVPP-PRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 PP P ++PP P + PP G V PP S ++V PP S ++ P + + Sbjct: 366 PPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTA 425 Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEG---APGWAGRWGRVPLARSPPQVP 193 + + A P S + P A A G P W G P A P VP Sbjct: 426 AGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVP 477 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 55.8 bits (133), Expect = 3e-08 Identities = 47/147 (31%), Positives = 57/147 (38%), Gaps = 8/147 (5%) Query: 77 LRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLP 136 L G ++PPP P ++PPP P S PPP P S LPP PPP P S + Sbjct: 463 LHQGKGMMPPP--PMGMMPPPPPPPSGQPPP--PPSGPLPPWQQQQQQPPPPPPPSSSMA 518 Query: 137 PRSPDSVVPPARSPDSGGRAGS--PRSLAPPAAARAEGAPGWAGRWGRVPL--ARSPPQV 192 +P + + GS P AAA + GAP G VPL PP Sbjct: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLP 578 Query: 193 PSRPPSLSQPLSSRVSLYELLFPSWPP 219 P PP P + P PP Sbjct: 579 PGAPPPPPPPPPGSAGMMYAPPPPPPP 605 Score = 38.1 bits (87), Expect = 0.006 Identities = 42/143 (29%), Positives = 50/143 (34%), Gaps = 47/143 (32%) Query: 45 SSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPP-----------PGSPDSV 93 SS + LPW +N +T G +PP PG+P Sbjct: 515 SSMASSTPLPWQQNTT-------------TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQ 561 Query: 94 VPPPRSP--DSVVPP--PGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARS 149 P P V PP PG+P PP P PPPGS + PP P PP Sbjct: 562 GNPTMVPLPPGVQPPLPPGAP-----PPPPP----PPPGSAGMMYAPPPPP----PPPMD 608 Query: 150 PDS------GGRAGSPRSLAPPA 166 P + G AG P PPA Sbjct: 609 PSNFVTMMGMGVAGMPPFGMPPA 631 Score = 33.1 bits (74), Expect = 0.19 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPP 137 PPPGS + PP P PPP P + V + +PP G P + PP Sbjct: 588 PPPGSAGMMYAPPPPP----PPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPP 636 Score = 27.7 bits (60), Expect = 8.0 Identities = 28/117 (23%), Positives = 40/117 (34%), Gaps = 6/117 (5%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 P P S S P +P + P P +P + PP + P +S R + Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGM- 382 Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQ 201 GG G P S P + G G + P PP + PP ++Q Sbjct: 383 ---HGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN--PNGPPPPWMQPPPPPMNQ 434 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 55.8 bits (133), Expect = 3e-08 Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 20/126 (15%) Query: 85 PPPGSPDSVVPPP---RSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVL-----P 136 PPP P S PPP + P+ VV P + ++ P + P+ PPP +P+ L P Sbjct: 729 PPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP 788 Query: 137 PRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRP 196 P P+ SP+ G +GSP ++ PAA+ + L PP P P Sbjct: 789 P--PEEAFFSVASPEPAGPSGSPELVSSPAASSSSA----------TALQIQPPGSPDPP 836 Query: 197 PSLSQP 202 P+ P Sbjct: 837 PAPPAP 842 Score = 47.4 bits (111), Expect = 1e-05 Identities = 44/130 (33%), Positives = 54/130 (41%), Gaps = 20/130 (15%) Query: 86 PPGSPDSVVPPPRSPDSV----VPPPGSPDSVVLPPRSPDSVVPPPGSPDSVV-LPPRSP 140 P GSP+ V P S S + PPGSPD PP +P + P +P V LP + P Sbjct: 805 PSGSPELVSSPAASSSSATALQIQPPGSPD----PPPAPPAPAPASSAPGHVAKLPQKEP 860 Query: 141 DSVVPPARSP--DSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198 P D G +P SL R+ GAPG A P P P +P Sbjct: 861 VGCSKGGGPPREDVGAPLVTP-SLLQMVRLRSVGAPGGA------PTPALGPSAPQKP-- 911 Query: 199 LSQPLSSRVS 208 L + LS R S Sbjct: 912 LRRALSGRAS 921 Score = 44.3 bits (103), Expect = 8e-05 Identities = 36/147 (24%), Positives = 57/147 (38%), Gaps = 25/147 (17%) Query: 78 RVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDS--VVLPPRSPDSVVP-PPGSPDSVV 134 R G +++ P G + P P+ P PPP P S P + +VVP P + D+ Sbjct: 645 RSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASP 704 Query: 135 LPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPS 194 P +P + + P + + SP PP + PP P+ Sbjct: 705 QSPPTPQTTLTPLQESPVISKDQSPPPSPPP--------------------SYHPPPPPT 744 Query: 195 RPPS--LSQPLSSRVSLYELLFPSWPP 219 + P + P +S + L P+WPP Sbjct: 745 KKPEVVVEAPSASETAEEPLQDPNWPP 771 Score = 42.4 bits (98), Expect = 3e-04 Identities = 38/137 (27%), Positives = 53/137 (38%), Gaps = 8/137 (5%) Query: 84 VPPPGSPDSVVPPPRSPDSVVPPPGSPDSVV-LPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 + PPGSPD PP +P + P +P V LP + P G P V P S Sbjct: 827 IQPPGSPD----PPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882 Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202 ++ R G G+P P+A + +GR VP S R + S Sbjct: 883 LLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA 942 Query: 203 LSSRVSLYELLFPSWPP 219 S +S + P+ PP Sbjct: 943 ASEGLSSAQ---PNGPP 956 Score = 34.7 bits (78), Expect = 0.066 Identities = 36/142 (25%), Positives = 51/142 (35%), Gaps = 19/142 (13%) Query: 80 GAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPG-SPDSVVLPPR 138 GA P P +P + P SP PP SP+ + P S P P + PP Sbjct: 544 GAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPA 603 Query: 139 SPDSVVPPARSPDSGGRA-GSPRSLAPPAAARAEGAPGWAGRWG---------------- 181 SP PP + R+ G+ S + + + P + R G Sbjct: 604 SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPH 663 Query: 182 -RVPLARSPPQVPSRPPSLSQP 202 +VP SPP R P+ + P Sbjct: 664 PKVPAPFSPPPSKPRSPNPAAP 685 Score = 29.6 bits (65), Expect = 2.1 Identities = 30/107 (28%), Positives = 39/107 (36%), Gaps = 24/107 (22%) Query: 67 IRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSV-------------VPPPGSPD-- 111 +R+ C S G P G P++ PP+SP S + P SP+ Sbjct: 934 VRLKAC-SLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQ 992 Query: 112 -----SVVLPPRSPDSVVPPPGSPDSVVLPP---RSPDSVVPPARSP 150 ++V RS PP S PP R P VPP SP Sbjct: 993 ADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASP 1039 Score = 29.3 bits (64), Expect = 2.8 Identities = 16/41 (39%), Positives = 18/41 (43%), Gaps = 4/41 (9%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 126 P SP + P R P VPPP SP PR+ PP Sbjct: 1015 PKKSPKAPPPVARKPSVGVPPPASPSY----PRAEPLTAPP 1051 Score = 27.7 bits (60), Expect = 8.0 Identities = 20/58 (34%), Positives = 23/58 (39%), Gaps = 7/58 (12%) Query: 92 SVVPPPRSPDSVVPPPGSPDSVVLPP---RSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146 ++V RS PP S PP R P VPPP SP PR+ PP Sbjct: 998 NLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSY----PRAEPLTAPP 1051 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 55.5 bits (132), Expect = 4e-08 Identities = 41/118 (34%), Positives = 46/118 (38%), Gaps = 12/118 (10%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP--PPGSPDSVVLPPR---S 139 PPPG P P + PPPG P PP+ S P PPG P PP+ Sbjct: 52 PPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQGP--PPQGGNQ 107 Query: 140 PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 P PP P G R PP + +G P G R P RSPP P PP Sbjct: 108 PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP-QGDKSRSP--RSPPGKPQGPP 162 Score = 50.8 bits (120), Expect = 9e-07 Identities = 38/129 (29%), Positives = 43/129 (33%), Gaps = 20/129 (15%) Query: 85 PPP---GSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP----------PPGSPD 131 PPP P PPP P P G PP P P PPG P Sbjct: 161 PPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQ 220 Query: 132 SVVLPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARS 188 PP+ P PP P G + PP + +G P G + ARS Sbjct: 221 GP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG--SKSQSARS 276 Query: 189 PPQVPSRPP 197 PP P PP Sbjct: 277 PPGKPQGPP 285 Score = 45.8 bits (107), Expect = 3e-05 Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 25/131 (19%) Query: 85 PPP---GSPDSVVPPPRSPDSV----------VPPPGSPDSVVLPPRSPDSVVP--PPGS 129 PPP P PPP P PPPG P PP+ S P PPG Sbjct: 100 PPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP--PPQGDKSRSPRSPPGK 157 Query: 130 PDSVVLPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA 186 P PP+ P PP P G + PP + +G P + + + Sbjct: 158 PQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP---PQGDKSRSS 212 Query: 187 RSPPQVPSRPP 197 +SPP P PP Sbjct: 213 QSPPGKPQGPP 223 Score = 43.5 bits (101), Expect = 1e-04 Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 29/119 (24%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRS----PDSVVPPPGSPDSVVLPPRSP 140 PPPG P P + PPPG P PP S PPG P P Sbjct: 235 PPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPAQGGSKSQSARSPPGKPQG----PPQQ 287 Query: 141 DSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQ--VPSRPP 197 + P P +GG P++ P A + +G P PPQ PSRPP Sbjct: 288 EGNNPQGPPPPAGGNPQQPQA---PPAGQPQGPP-------------RPPQGGRPSRPP 330 Score = 35.4 bits (80), Expect = 0.038 Identities = 32/111 (28%), Positives = 40/111 (36%), Gaps = 23/111 (20%) Query: 88 GSPDSVVPPP-RSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146 G+P P P PPPG P PPP + P+ P P Sbjct: 34 GNPQGPSPQGGNKPQGPPPPPGKPQG------------PPPQGGNK----PQGPPPPGKP 77 Query: 147 ARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 P G ++ SPRS PP + +G P G + P PP P PP Sbjct: 78 QGPPPQGDKSRSPRS--PP--GKPQGPPPQGGNQPQGP--PPPPGKPQGPP 122 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 55.1 bits (131), Expect = 5e-08 Identities = 44/130 (33%), Positives = 53/130 (40%), Gaps = 8/130 (6%) Query: 77 LRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLP 136 L G ++PPP P ++PPP P S PPP P S LPP PPP P S + Sbjct: 463 LHQGKGMMPPP--PMGMMPPPPPPPSGQPPP--PPSGPLPPWQQQQQQPPPPPPPSSSMA 518 Query: 137 PRSPDSVVPPARSPDSGGRAGS--PRSLAPPAAARAEGAPGWAGRWGRVPL--ARSPPQV 192 +P + + GS P AAA + GAP G VPL PP Sbjct: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLP 578 Query: 193 PSRPPSLSQP 202 P PP P Sbjct: 579 PGAPPPPPPP 588 Score = 42.4 bits (98), Expect = 3e-04 Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 38/149 (25%) Query: 45 SSKFPTNTLPWSKNALFSKVVFIRVHLCKSTVLRVGAKVVPP-----------PGSPDSV 93 SS + LPW +N +T G +PP PG+P Sbjct: 515 SSMASSTPLPWQQNTT-------------TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQ 561 Query: 94 VPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSG 153 P P +PP P LPP +P PPP +++PPR D P S D Sbjct: 562 GNPTMVP---LPPGVQPP---LPPGAPPPPPPPPPGSAGMMIPPRGGDG--PSHESED-- 611 Query: 154 GRAGSPRSLAPPAAARAEGAPGWAGRWGR 182 PR L + + P W G +G+ Sbjct: 612 ----FPRPLVTLPGRQPQQRPWWTGWFGK 636 Score = 27.7 bits (60), Expect = 8.0 Identities = 28/117 (23%), Positives = 40/117 (34%), Gaps = 6/117 (5%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 P P S S P +P + P P +P + PP + P +S R + Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGM- 382 Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQ 201 GG G P S P + G G + P PP + PP ++Q Sbjct: 383 ---HGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN--PNGPPPPWMQPPPPPMNQ 434 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 55.1 bits (131), Expect = 5e-08 Identities = 39/120 (32%), Positives = 45/120 (37%), Gaps = 14/120 (11%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPD----SVVPPPGSPDSVVLPPR-- 138 PPPG P P + PPPG P PP D S PPG P PP+ Sbjct: 196 PPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDNKSQSARSPPGKPQGP--PPQGG 250 Query: 139 -SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 P PP P G + PP + +G P G R +RSPP P PP Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR--SSRSPPGKPQGPP 308 Score = 50.8 bits (120), Expect = 9e-07 Identities = 39/130 (30%), Positives = 44/130 (33%), Gaps = 21/130 (16%) Query: 85 PPP---GSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP-----------PPGSP 130 PPP P PPP P P G+ PP P P PPG P Sbjct: 245 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKP 304 Query: 131 DSVVLPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187 PP+ P PP P G + PP + +G P G R AR Sbjct: 305 QGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR--SAR 360 Query: 188 SPPQVPSRPP 197 SPP P PP Sbjct: 361 SPPGKPQGPP 370 Score = 50.4 bits (119), Expect = 1e-06 Identities = 38/122 (31%), Positives = 45/122 (36%), Gaps = 20/122 (16%) Query: 86 PPGSPDSVVPPPRS---PDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 PPG P PPP+ P PPPG P + PPPG P PP D+ Sbjct: 176 PPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDN 230 Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGR-------WGRVPLARSPPQVPSR 195 ARSP G P+ P + +G P G+ G P PP P Sbjct: 231 KSQSARSP-----PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 285 Query: 196 PP 197 PP Sbjct: 286 PP 287 Score = 48.5 bits (114), Expect = 4e-06 Identities = 40/131 (30%), Positives = 46/131 (35%), Gaps = 24/131 (18%) Query: 85 PPP---GSPDSVVPPPRSPDSV----------VPPPGSPDSVVLPPRSPDSVVP--PPGS 129 PPP P PPP P PPPG P PP+ S P PPG Sbjct: 60 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGK 117 Query: 130 PDSVVLPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA 186 P PP+ P PP P G + PP + +G P R + Sbjct: 118 PQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR--SS 173 Query: 187 RSPPQVPSRPP 197 RSPP P PP Sbjct: 174 RSPPGKPQGPP 184 Score = 44.7 bits (104), Expect = 6e-05 Identities = 35/120 (29%), Positives = 45/120 (37%), Gaps = 16/120 (13%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPP---RSPDSVVPPPGSPDSVVLPP----- 137 PPG P PPP+ + PP P PP + PPPG P PP Sbjct: 114 PPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDN 168 Query: 138 RSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 +S S PP + + G+ PP + +G P + G P PP P PP Sbjct: 169 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP---PQGGNKPQGPPPPGKPQGPP 225 Score = 43.9 bits (102), Expect = 1e-04 Identities = 38/122 (31%), Positives = 46/122 (37%), Gaps = 35/122 (28%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPD---SVVPPPGSPDSVVLPPR--- 138 PPPG P P + PPPG P PP+ S PPG P PP+ Sbjct: 320 PPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGGSKSRSARSPPGKPQG---PPQQEG 374 Query: 139 -SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQ--VPSR 195 +P PPA G+P+ P A + +G P PPQ PSR Sbjct: 375 NNPQGPPPPA--------GGNPQQPQAPPAGQPQGPP-------------RPPQGGRPSR 413 Query: 196 PP 197 PP Sbjct: 414 PP 415 Score = 43.1 bits (100), Expect = 2e-04 Identities = 37/126 (29%), Positives = 43/126 (34%), Gaps = 26/126 (20%) Query: 85 PPPGSPDSVVP----------PPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVV 134 PPPG P P PP P PP D+ RS PPG P Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGDNKSRSSRS------PPGKPQGP- 183 Query: 135 LPPR---SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQ 191 PP+ P PP P G + PP + +G P + ARSPP Sbjct: 184 -PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD--NKSQSARSPPG 240 Query: 192 VPSRPP 197 P PP Sbjct: 241 KPQGPP 246 Score = 41.2 bits (95), Expect = 7e-04 Identities = 36/115 (31%), Positives = 43/115 (37%), Gaps = 13/115 (11%) Query: 85 PPPGS--PDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 PP G P PP P PPP + PP P P G P P+ P Sbjct: 40 PPQGGNKPQGPPSPPGKPQG--PPPQGGNQPQGPPPPPGK---PQGPPPQGGNKPQGPPP 94 Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 P P G ++ SPRS PP + +G P G + P PP P PP Sbjct: 95 PGKPQGPPPQGDKSRSPRS--PP--GKPQGPPPQGGNQPQGP--PPPPGKPQGPP 143 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 53.5 bits (127), Expect = 1e-07 Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 31/220 (14%) Query: 6 SQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNALFSKVV 65 S++T +E Q + ++ E Q L G + + L + L +V Sbjct: 481 SELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVA 540 Query: 66 FIRVHL---CKSTVLRVGAKVVPPPGSPDSVVPPPRSP-----DSVVPPPGSPDSVVLPP 117 + L K A + PP P PP P +++PPP +P PP Sbjct: 541 KLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP 600 Query: 118 RSPDSVVPPPGSPDSVVL---------------PPRSPDSVVPPARSPDSGGRAGSPRSL 162 P PPP P V + PP S D+ +PP G SP SL Sbjct: 601 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 660 Query: 163 APPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202 P P G AR PP P P S P Sbjct: 661 --PGGTAIPPPPPLPGS------ARIPPPPPPLPGSAGIP 692 Score = 52.4 bits (124), Expect = 3e-07 Identities = 39/117 (33%), Positives = 49/117 (41%), Gaps = 9/117 (7%) Query: 83 VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVL--PPRSPDSVV---PPPGSPDSVVLPP 137 ++PPP +P PP P PPP P V + PP P PPP S D+ + PP Sbjct: 586 IIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP 645 Query: 138 RS-PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVP 193 P+ V P+ S GG A P P +A P G G P PP +P Sbjct: 646 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP---PPPPLP 699 Score = 42.7 bits (99), Expect = 2e-04 Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 30/141 (21%) Query: 80 GAKVVPP----PGSPDSVVPPPRSPDSV---VPPPGSPDSVVLPPRSP-----DSVVPPP 127 G +PP PGS PPP P S PPP P +PP P + PPP Sbjct: 662 GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP 721 Query: 128 GSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187 P +PP P +PP PP AP +G P Sbjct: 722 PFPGGPGIPPPPPGMGMPP----------------PPPFGFGVPAAP--VLPFGLTPKKL 763 Query: 188 SPPQVPSRPPSLSQPLSSRVS 208 P+V R P+ S+ ++ +S Sbjct: 764 YKPEVQLRRPNWSKLVAEDLS 784 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 53.5 bits (127), Expect = 1e-07 Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 31/220 (14%) Query: 6 SQVTISNECQWHLNQLSDHTEPSEQHLPGTHAFAEVQSRSSKFPTNTLPWSKNALFSKVV 65 S++T +E Q + ++ E Q L G + + L + L +V Sbjct: 490 SELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVA 549 Query: 66 FIRVHL---CKSTVLRVGAKVVPPPGSPDSVVPPPRSP-----DSVVPPPGSPDSVVLPP 117 + L K A + PP P PP P +++PPP +P PP Sbjct: 550 KLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP 609 Query: 118 RSPDSVVPPPGSPDSVVL---------------PPRSPDSVVPPARSPDSGGRAGSPRSL 162 P PPP P V + PP S D+ +PP G SP SL Sbjct: 610 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 669 Query: 163 APPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202 P P G AR PP P P S P Sbjct: 670 --PGGTAIPPPPPLPGS------ARIPPPPPPLPGSAGIP 701 Score = 52.4 bits (124), Expect = 3e-07 Identities = 39/117 (33%), Positives = 49/117 (41%), Gaps = 9/117 (7%) Query: 83 VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVL--PPRSPDSVV---PPPGSPDSVVLPP 137 ++PPP +P PP P PPP P V + PP P PPP S D+ + PP Sbjct: 595 IIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP 654 Query: 138 RS-PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVP 193 P+ V P+ S GG A P P +A P G G P PP +P Sbjct: 655 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP---PPPPLP 708 Score = 42.7 bits (99), Expect = 2e-04 Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 30/141 (21%) Query: 80 GAKVVPP----PGSPDSVVPPPRSPDSV---VPPPGSPDSVVLPPRSP-----DSVVPPP 127 G +PP PGS PPP P S PPP P +PP P + PPP Sbjct: 671 GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP 730 Query: 128 GSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187 P +PP P +PP PP AP +G P Sbjct: 731 PFPGGPGIPPPPPGMGMPP----------------PPPFGFGVPAAP--VLPFGLTPKKL 772 Query: 188 SPPQVPSRPPSLSQPLSSRVS 208 P+V R P+ S+ ++ +S Sbjct: 773 YKPEVQLRRPNWSKLVAEDLS 793 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 53.1 bits (126), Expect = 2e-07 Identities = 40/120 (33%), Positives = 53/120 (44%), Gaps = 9/120 (7%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSV 143 PP SP S PP ++P S+ PP P PP SP S PPP +P + PP Sbjct: 458 PPVSP-SATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPL--QLA 513 Query: 144 VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPL 203 PP ++P + +PPA+ + + PLA PPQ PP L+ PL Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA---PPVLAAPL 570 Score = 48.9 bits (115), Expect = 3e-06 Identities = 45/145 (31%), Positives = 60/145 (41%), Gaps = 20/145 (13%) Query: 74 STVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPP--GSPDSVVLPPRSPDSVVPPPGSPD 131 S L+ +P P PPP++P ++ PP P PP SP P P +P+ Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP-LATPSPQAPN 429 Query: 132 SVVL--------PPRSPD---SVVPPARSPDSGGRAGSPRSLAPP--AAARAEGAPGWAG 178 ++ + PP SP PPA P S + +P S APP AA + P Sbjct: 430 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS--PSATPPSQAPPSLAAPPLQVPPSPPA 487 Query: 179 RWGRVPLARSPPQVPSRPPSLSQPL 203 P A PPQ P PP + PL Sbjct: 488 SPPMSPSATPPPQAP--PPLAAPPL 510 Score = 46.6 bits (109), Expect = 2e-05 Identities = 47/163 (28%), Positives = 69/163 (42%), Gaps = 37/163 (22%) Query: 85 PPPGSPDSV-VPPPRSPDS----------VVPPPGSPDSVVL--------PPRSPDSVVP 125 PPP +P ++ +PP ++P S P P +P+++ + PP SP P Sbjct: 392 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451 Query: 126 --PPGSP---DSVVLPPRSPDSV-VPPARSPDS--GGRAGSPRSLAPPAAARAEGAPGWA 177 PP SP S P ++P S+ PP + P S SP + PP A AP Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--- 508 Query: 178 GRWGRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW 220 + LA+ PPQ PP+L+ P + FP P+ Sbjct: 509 ----PLQLAKPPPQA---PPALATPPLQALPSPPASFPGQAPF 544 Score = 45.4 bits (106), Expect = 4e-05 Identities = 48/162 (29%), Positives = 60/162 (37%), Gaps = 29/162 (17%) Query: 79 VGAKVVPPPGSPDSVVPPPRS--PDSVVPPPGSPDSVVLPPRSPDSVV--------PPPG 128 V PP +P S+ PP P PP SP S PP++P + PPP Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQLAKPPPQ 518 Query: 129 SPDSVVLP-----PRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRV 183 +P ++ P P P S A S SP + PP A AP + Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LL 571 Query: 184 PLARSPP-----QVPSRPPSLSQPLS-SRVSLYELLFPSWPP 219 + SPP Q P RPP+ S S L L P PP Sbjct: 572 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613 Score = 40.4 bits (93), Expect = 0.001 Identities = 51/156 (32%), Positives = 64/156 (41%), Gaps = 27/156 (17%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDS-----------------VVLPPRSPDSVVPPP 127 P P +P S PP S ++ PP +P S + PP SP PPP Sbjct: 337 PLPLAPPSPSAPP-SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP-LATPPP 394 Query: 128 GSPDSVVLPP-RSPDSVVPPARSPDSGGRAGSPRSLAPPA-AARAEGAPGWAGRWGRVPL 185 +P ++ LPP ++P S PPA P S SP+ AP A A AP V Sbjct: 395 QAPPALALPPLQAPPS--PPASPPLSPLATPSPQ--APNALAVHLLQAPFSPPPSPPVQA 450 Query: 186 ARSPPQVPSRPPSLSQPLSSRVSLY--ELLFPSWPP 219 SPP P PS + P + SL L P PP Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486 Score = 38.5 bits (88), Expect = 0.005 Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 11/122 (9%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 PP PD+ V PR ++ P P P P RSP S + P +P+ + Sbjct: 589 PPTPGPDTSVSGPRLTLALAPGPPPP-----PSRSPSSTLSGPDLAGHSSSATSTPEEL- 642 Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA-RSPPQVPSRPPSLSQPL 203 R DSG G+ S PP A A P R PLA R P P P + P Sbjct: 643 ---RGYDSGPEGGAAAS-PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 698 Query: 204 SS 205 S+ Sbjct: 699 SA 700 Score = 28.9 bits (63), Expect = 3.6 Identities = 32/115 (27%), Positives = 42/115 (36%), Gaps = 17/115 (14%) Query: 80 GAKVVPPPGSPDSVVPPPRSPDSVVPP------PGSPDSVVLPPRSPDSVVPPPGSPDSV 133 GA PPP + + P PP PG+P + PP + PGS D + Sbjct: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP--LPWPPAT------GPGSADGL 703 Query: 134 --VLPPRSPDSVVPPARSPDSGGRAG-SPRSLAPPAAARAEGAPGWAGRWGRVPL 185 + P+S P + D G G S A A A A R G +PL Sbjct: 704 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 758 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 53.1 bits (126), Expect = 2e-07 Identities = 40/120 (33%), Positives = 53/120 (44%), Gaps = 9/120 (7%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSV 143 PP SP S PP ++P S+ PP P PP SP S PPP +P + PP Sbjct: 419 PPVSP-SATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPL--QLA 474 Query: 144 VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPL 203 PP ++P + +PPA+ + + PLA PPQ PP L+ PL Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA---PPVLAAPL 531 Score = 48.9 bits (115), Expect = 3e-06 Identities = 45/145 (31%), Positives = 60/145 (41%), Gaps = 20/145 (13%) Query: 74 STVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPP--GSPDSVVLPPRSPDSVVPPPGSPD 131 S L+ +P P PPP++P ++ PP P PP SP P P +P+ Sbjct: 332 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP-LATPSPQAPN 390 Query: 132 SVVL--------PPRSPD---SVVPPARSPDSGGRAGSPRSLAPP--AAARAEGAPGWAG 178 ++ + PP SP PPA P S + +P S APP AA + P Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS--PSATPPSQAPPSLAAPPLQVPPSPPA 448 Query: 179 RWGRVPLARSPPQVPSRPPSLSQPL 203 P A PPQ P PP + PL Sbjct: 449 SPPMSPSATPPPQAP--PPLAAPPL 471 Score = 46.6 bits (109), Expect = 2e-05 Identities = 47/163 (28%), Positives = 69/163 (42%), Gaps = 37/163 (22%) Query: 85 PPPGSPDSV-VPPPRSPDS----------VVPPPGSPDSVVL--------PPRSPDSVVP 125 PPP +P ++ +PP ++P S P P +P+++ + PP SP P Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412 Query: 126 --PPGSP---DSVVLPPRSPDSV-VPPARSPDS--GGRAGSPRSLAPPAAARAEGAPGWA 177 PP SP S P ++P S+ PP + P S SP + PP A AP Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--- 469 Query: 178 GRWGRVPLARSPPQVPSRPPSLSQPLSSRVSLYELLFPSWPPW 220 + LA+ PPQ PP+L+ P + FP P+ Sbjct: 470 ----PLQLAKPPPQA---PPALATPPLQALPSPPASFPGQAPF 505 Score = 45.4 bits (106), Expect = 4e-05 Identities = 48/162 (29%), Positives = 60/162 (37%), Gaps = 29/162 (17%) Query: 79 VGAKVVPPPGSPDSVVPPPRS--PDSVVPPPGSPDSVVLPPRSPDSVV--------PPPG 128 V PP +P S+ PP P PP SP S PP++P + PPP Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQLAKPPPQ 479 Query: 129 SPDSVVLP-----PRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRV 183 +P ++ P P P S A S SP + PP A AP + Sbjct: 480 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LL 532 Query: 184 PLARSPP-----QVPSRPPSLSQPLS-SRVSLYELLFPSWPP 219 + SPP Q P RPP+ S S L L P PP Sbjct: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574 Score = 42.7 bits (99), Expect = 2e-04 Identities = 51/156 (32%), Positives = 64/156 (41%), Gaps = 27/156 (17%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDS-----------------VVLPPRSPDSVVPPP 127 P P +P S PP S ++ PP +P S + PP SP PPP Sbjct: 298 PSPSAPPSPSAPP-SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP-LATPPP 355 Query: 128 GSPDSVVLPP-RSPDSVVPPARSPDSGGRAGSPRSLAPPA-AARAEGAPGWAGRWGRVPL 185 +P ++ LPP ++P S PPA P S SP+ AP A A AP V Sbjct: 356 QAPPALALPPLQAPPS--PPASPPLSPLATPSPQ--APNALAVHLLQAPFSPPPSPPVQA 411 Query: 186 ARSPPQVPSRPPSLSQPLSSRVSLY--ELLFPSWPP 219 SPP P PS + P + SL L P PP Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 447 Score = 38.5 bits (88), Expect = 0.005 Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 11/122 (9%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 PP PD+ V PR ++ P P P P RSP S + P +P+ + Sbjct: 550 PPTPGPDTSVSGPRLTLALAPGPPPP-----PSRSPSSTLSGPDLAGHSSSATSTPEEL- 603 Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA-RSPPQVPSRPPSLSQPL 203 R DSG G+ S PP A A P R PLA R P P P + P Sbjct: 604 ---RGYDSGPEGGAAAS-PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 659 Query: 204 SS 205 S+ Sbjct: 660 SA 661 Score = 37.7 bits (86), Expect = 0.008 Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 7/83 (8%) Query: 95 PPPRSPDSVVP-PPGSPDSVVLPPRSPDS--VVPPPGSPDSVVLPPRSPDSVVPPARSPD 151 P R+P + P PPGSP PP +P + V+ G+ L R+ + A P+ Sbjct: 17 PAARAPGLLTPRPPGSPRPP--PPVTPAALRVLGAAGAVGRKPLAERAGG--IGGATIPE 72 Query: 152 SGGRAGSPRSLAPPAAARAEGAP 174 S RAG R+ PPA+ R E AP Sbjct: 73 SAPRAGPTRTSRPPASGRGERAP 95 Score = 36.2 bits (82), Expect = 0.023 Identities = 30/110 (27%), Positives = 39/110 (35%), Gaps = 17/110 (15%) Query: 100 PDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRA-GS 158 P V PP + P S P P +P S PP PPA P + GS Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332 Query: 159 PR-----------SLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 P L+P A + P A +P ++PP P+ PP Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALA-----LPPLQAPPSPPASPP 377 Score = 33.1 bits (74), Expect = 0.19 Identities = 36/129 (27%), Positives = 44/129 (34%), Gaps = 15/129 (11%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP-----PGSPDSVVLPPRSP 140 P SP P R P P L P V PP P P +P Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298 Query: 141 DSVVPPARS-PDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRV------PLARSPPQVP 193 PP+ S P S SP + P A + G+P + PLA PPQ Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA- 357 Query: 194 SRPPSLSQP 202 PP+L+ P Sbjct: 358 --PPALALP 364 Score = 28.9 bits (63), Expect = 3.6 Identities = 32/115 (27%), Positives = 42/115 (36%), Gaps = 17/115 (14%) Query: 80 GAKVVPPPGSPDSVVPPPRSPDSVVPP------PGSPDSVVLPPRSPDSVVPPPGSPDSV 133 GA PPP + + P PP PG+P + PP + PGS D + Sbjct: 613 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP--LPWPPAT------GPGSADGL 664 Query: 134 --VLPPRSPDSVVPPARSPDSGGRAG-SPRSLAPPAAARAEGAPGWAGRWGRVPL 185 + P+S P + D G G S A A A A R G +PL Sbjct: 665 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 719 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 53.1 bits (126), Expect = 2e-07 Identities = 44/162 (27%), Positives = 58/162 (35%), Gaps = 30/162 (18%) Query: 60 LFSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRS 119 L + +RV S R A+V PP PP P G+P + Sbjct: 76 LIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRA-------PRGAPAAAAAAAPP 128 Query: 120 PDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRA-------------------GSPR 160 P PPP +P + P R+P + A +P S G A +P Sbjct: 129 PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPP 188 Query: 161 SLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202 ++APPA R P A R +P PP P PP QP Sbjct: 189 AVAPPAGPRRAPPPAVAAREPPLP----PPPQPPAPPQQQQP 226 Score = 48.9 bits (115), Expect = 3e-06 Identities = 34/113 (30%), Positives = 50/113 (44%), Gaps = 14/113 (12%) Query: 94 VPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSG 153 V PPR + PP +P P + + PPP PP +P + PAR+P Sbjct: 99 VQPPRRGATPPAPPRAPRGA---PAAAAAAAPPPTPAPP---PPPAPVAAAAPARAP--- 149 Query: 154 GRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLSSR 206 RA + + APP+ A+ P R R +PP P+ PP+++ P R Sbjct: 150 -RAAAAAATAPPSPGPAQPGP----RAQRAAPLAAPPPAPAAPPAVAPPAGPR 197 Score = 35.0 bits (79), Expect = 0.050 Identities = 33/108 (30%), Positives = 44/108 (40%), Gaps = 22/108 (20%) Query: 85 PPPGSPDSVVPP--PRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 P P +P +V PP PR PPP + R P +PPP P + PP+ Sbjct: 182 PAPAAPPAVAPPAGPRR----APPP------AVAAREPP--LPPPPQPPA---PPQQQQP 226 Query: 143 VVPPARSPDSGG---RAGSPRSLAPPAAARAEGAPGWAGRWGRVPLAR 187 P + P GG G+ R ++ R G G AG GR+ R Sbjct: 227 PPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAG--GRLTRGR 272 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 52.4 bits (124), Expect = 3e-07 Identities = 44/133 (33%), Positives = 54/133 (40%), Gaps = 9/133 (6%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPP-PGSPDSVVLPPRSPDS 142 PP S +PPP P +PPP S P PP P+S PP PG P PP P Sbjct: 672 PPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGP-----PPAPPPP 726 Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLA-RSPPQVPSRPPSLSQ 201 + P P GS S P A P W R+ ++ RS P+ SL + Sbjct: 727 GLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEE 786 Query: 202 PLSSRVSLYELLF 214 P S +E LF Sbjct: 787 PDIRDPSEFEYLF 799 Score = 48.5 bits (114), Expect = 4e-06 Identities = 38/118 (32%), Positives = 44/118 (37%), Gaps = 12/118 (10%) Query: 82 KVVPPPGSPDSVVPPPRSPD---SVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPR 138 K +PPP P S+ PPP P S+ P P P PP P PPP P S PP Sbjct: 643 KALPPP--PASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPP 700 Query: 139 SPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRP 196 P PP + + G P PP PG L S Q P +P Sbjct: 701 PPPP--PPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLF-----FGLGSSSSQCPRKP 751 >gi|15529996 son of sevenless homolog 1 [Homo sapiens] Length = 1333 Score = 52.4 bits (124), Expect = 3e-07 Identities = 49/155 (31%), Positives = 61/155 (39%), Gaps = 28/155 (18%) Query: 84 VPPPGSPDSVVPPPRSPDSVVPPPGSPDSVV---------LPPRSPDSVVPPP----GSP 130 VPPP VPP R P+S P SP ++ +PPR P S P Sbjct: 1149 VPPP------VPPRRRPESA-PAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDR 1201 Query: 131 DSVVLPPRSPDSVVP--PARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARS 188 S+ PP SP + P P R+PD + SP L PP + P Sbjct: 1202 TSISDPPESPPLLPPREPVRTPDVF--SSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPP 1259 Query: 189 PPQVPS----RPPSLSQPLSSRVSLYELLFPSWPP 219 PPQ PS R S PL+ V L+ + P PP Sbjct: 1260 PPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPP 1294 Score = 28.1 bits (61), Expect = 6.1 Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 49/156 (31%) Query: 86 PPGSPDSVVPPPRSPDS-VVPPPGSPDS---------------------------VVLP- 116 P +S P SP + + PPP S S V LP Sbjct: 1069 PESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPH 1128 Query: 117 -PRSPD-SVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSL------APPA-A 167 PRS S + D V +PP VPP R P+S SP + +PPA Sbjct: 1129 GPRSASVSSISLTKGTDEVPVPPP-----VPPRRRPESAPAESSPSKIMSKHLDSPPAIP 1183 Query: 168 ARAEGAPGWAGRWG---RVPLA---RSPPQVPSRPP 197 R + ++ R+ R ++ SPP +P R P Sbjct: 1184 PRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREP 1219 >gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 preproprotein [Homo sapiens] Length = 198 Score = 52.4 bits (124), Expect = 3e-07 Identities = 37/115 (32%), Positives = 43/115 (37%), Gaps = 16/115 (13%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVP--PPGSPDSVVLPPRSPDS 142 PPPG P P + PPPG P PP+ S P PPG P PP Sbjct: 52 PPPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQG---PP----- 101 Query: 143 VVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPP 197 P P G + PP + +G P G + ARSPP P PP Sbjct: 102 --PQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG--SKSQSARSPPGKPQGPP 152 Score = 48.9 bits (115), Expect = 3e-06 Identities = 42/126 (33%), Positives = 50/126 (39%), Gaps = 12/126 (9%) Query: 85 PPPGSPDSVVPPPRSPDSVVP--PPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 PPPG P PPP+ S P PPG P PP+ PPP + PP Sbjct: 72 PPPGKPQG--PPPQGDKSRSPRSPPGKPQGP--PPQGGKPQGPPPQGGNKPQGPPPPGKP 127 Query: 143 VVPPARSPDSGGRAGSP--RSLAPP--AAARAEGAPGWAGRWGRVPLA--RSPPQVPSRP 196 PPA+ A SP + PP +G P AG + P A PQ P RP Sbjct: 128 QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 187 Query: 197 PSLSQP 202 P +P Sbjct: 188 PQGGRP 193 Score = 38.1 bits (87), Expect = 0.006 Identities = 32/118 (27%), Positives = 41/118 (34%), Gaps = 26/118 (22%) Query: 88 GSPDSVVPPP-RSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPP 146 G+P P P PPPG P PPP + P+ P P Sbjct: 34 GNPQGPSPQGGNKPQGPPPPPGKPQG------------PPPQGGNK----PQGPPPPGKP 77 Query: 147 ARSPDSGGRAGSPRSL------APPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPS 198 P G ++ SPRS PP + +G P + G P PP P PP+ Sbjct: 78 QGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPP---PQGGNKPQGPPPPGKPQGPPA 132 >gi|156071470 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 [Homo sapiens] Length = 889 Score = 52.0 bits (123), Expect = 4e-07 Identities = 41/122 (33%), Positives = 53/122 (43%), Gaps = 13/122 (10%) Query: 80 GAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRS 139 GA P P P PP + P PPP P PP P PP P + LPP + Sbjct: 15 GATPAPGPPPPPPPAPPQQQP----PPPPPP----APPPGP-GPAPPQHPPRAEALPPEA 65 Query: 140 PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAP-GWAGRWGRVPLARSPPQVPSRPPS 198 D P R G P + P AA+ A+G+P G GR G + + P+ P+R P Sbjct: 66 ADEGGPRGRLRSRDSSCGRPGT--PGAASTAKGSPNGECGR-GEPQCSPAGPEGPARGPK 122 Query: 199 LS 200 +S Sbjct: 123 VS 124 Score = 45.4 bits (106), Expect = 4e-05 Identities = 37/116 (31%), Positives = 44/116 (37%), Gaps = 8/116 (6%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVV 144 PPPG P P + PPP SP PR+P P G P + + P P + Sbjct: 761 PPPG------PAPAAASPGPPPPASPPGAPASPRAP-RTSPYGGLPAAPLAGPALPARRL 813 Query: 145 PPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLS 200 A P S + P AP AA A R G P AR+ P R S S Sbjct: 814 SRASRPLSASQPSLPHG-APGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSAS 868 Score = 37.7 bits (86), Expect = 0.008 Identities = 42/155 (27%), Positives = 59/155 (38%), Gaps = 25/155 (16%) Query: 57 KNALFSKVVFIRVHLCKSTVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLP 116 +NA+ ++V + + L + PPP PPP S + ++ Sbjct: 687 ENAIIQEIVKYDREMVQQAELGQRVGLFPPP-------PPPPQVTSAIATLQQAAAMSFC 739 Query: 117 PRSPDSVVPPP--GSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAP 174 P+ +V P GSP V PP P P A SP G P +PP A + AP Sbjct: 740 PQVARPLVGPLALGSPRLVRRPPPGP---APAAASP------GPPPPASPPGAPASPRAP 790 Query: 175 GWAGRWGRVPLARSPPQVP-------SRPPSLSQP 202 + G + P +P SRP S SQP Sbjct: 791 RTSPYGGLPAAPLAGPALPARRLSRASRPLSASQP 825 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 51.6 bits (122), Expect = 5e-07 Identities = 42/129 (32%), Positives = 46/129 (35%), Gaps = 16/129 (12%) Query: 83 VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSP-- 140 + PPP PPP+ P PPP P P + PP S VV P Sbjct: 60 IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAP 119 Query: 141 --------DSVVPPARSPDSGGRAGS---PRSLAPPAAARA-EGAPGWAGRWGRVPLARS 188 S PPA P SG GS P PPA A GAP VP + Sbjct: 120 GVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVP--TT 177 Query: 189 PPQVPSRPP 197 PPQ PP Sbjct: 178 PPQAGGPPP 186 Score = 51.2 bits (121), Expect = 7e-07 Identities = 38/120 (31%), Positives = 41/120 (34%), Gaps = 12/120 (10%) Query: 88 GSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPA 147 G + PPP PPP P PP P PP P PP P P Sbjct: 55 GPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP----PPHPQPHQQQQPPPPPQDSSKPV 110 Query: 148 RSPDSG-----GRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSLSQP 202 + G G A S APPA GAP +G P PP V S PP P Sbjct: 111 VAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG---PTPTPPPAVTSAPPGAPPP 167 Score = 47.8 bits (112), Expect = 7e-06 Identities = 41/129 (31%), Positives = 49/129 (37%), Gaps = 11/129 (8%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGS--PDSVVLPPRSPDSVVPPPGS-PDSVVLPPRSPD 141 PPP DS P P GS P S PP +P + PPGS P PP + Sbjct: 99 PPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVT 158 Query: 142 SV---VPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRP-- 196 S PP P SG P++ PP A PG + G P ++P P Sbjct: 159 SAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP 218 Query: 197 ---PSLSQP 202 P LS P Sbjct: 219 GGGPGLSTP 227 Score = 31.2 bits (69), Expect = 0.73 Identities = 29/103 (28%), Positives = 33/103 (32%), Gaps = 5/103 (4%) Query: 85 PPPGSPDSVVP--PPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 PPP P S VP PP++ PP P P + P P G P P Sbjct: 165 PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGL 224 Query: 143 VVP---PARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGR 182 P P GG R PP + P G GR Sbjct: 225 STPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGR 267 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 51.2 bits (121), Expect = 7e-07 Identities = 38/123 (30%), Positives = 46/123 (37%), Gaps = 18/123 (14%) Query: 85 PPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVV-----PPPGSPDSVVLPPRS 139 PPP S PPP P + PPP PP P PPP S SV +PP Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPP 338 Query: 140 PDSVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQVPSRPPSL 199 P+ + PP P + +P PP + G P+A PP P PP Sbjct: 339 PNRMYPP---PPPALPSSAPSGPPPPPPSVL----------GVGPVAPPPPPPPPPPPGP 385 Query: 200 SQP 202 P Sbjct: 386 PPP 388 Score = 47.0 bits (110), Expect = 1e-05 Identities = 32/94 (34%), Positives = 38/94 (40%), Gaps = 7/94 (7%) Query: 85 PPPGSPDSVVPPP--RSPDSVVPPPG-SPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPD 141 PPP PPP R+P + PPP S SV +PP P+ + PPP LP +P Sbjct: 301 PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPP----ALPSSAPS 356 Query: 142 SVVPPARSPDSGGRAGSPRSLAPPAAARAEGAPG 175 PP S G P PP PG Sbjct: 357 GPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPG 390 Score = 43.1 bits (100), Expect = 2e-04 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 9/83 (10%) Query: 80 GAKVVPPPGSPDSVVPPP--RSPDSVVPPPG-----SPDSVVLPPRSPDSVVPPPGSPDS 132 GA PP +P + PPP P VPPP P LP +P PPP S Sbjct: 308 GAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLG 367 Query: 133 V--VLPPRSPDSVVPPARSPDSG 153 V V PP P PP P G Sbjct: 368 VGPVAPPPPPPPPPPPGPPPPPG 390 Score = 32.3 bits (72), Expect = 0.33 Identities = 22/52 (42%), Positives = 22/52 (42%), Gaps = 11/52 (21%) Query: 85 PPPGSPDSVV----PPPRSPDSVVP--PPGSPDSVVLPPRSPDSVVPPPGSP 130 PPP P S PPP S V P PP P PP P PPPG P Sbjct: 346 PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP-----PPPPPPGPPPPPGLP 392 Score = 30.4 bits (67), Expect = 1.2 Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 7/36 (19%) Query: 75 TVLRVGAKVVPPPGSPDSVVPPPRSPDSVVPPPGSP 110 +VL VG PPP PPP P PPPG P Sbjct: 364 SVLGVGPVAPPPP-------PPPPPPPGPPPPPGLP 392 >gi|56118221 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [Homo sapiens] Length = 666 Score = 51.2 bits (121), Expect = 7e-07 Identities = 39/102 (38%), Positives = 44/102 (43%), Gaps = 14/102 (13%) Query: 87 PGSPDSVVPPPRSP----DSVVPPPGSPDSVVLPPRSPDSVVPPP----GSPDSVVLPPR 138 P PD +PPP P D +PPP P + PP PD V PPP G S + PP Sbjct: 547 PAPPDDFLPPPPPPPPLDDPELPPP--PPDFMEPP--PDFVPPPPPSYAGIAGSELPPPP 602 Query: 139 SPDSVVPPARSPDSG--GRAGSPRSLAPPAAARAEGAPGWAG 178 P PA PDS A + R PP G PG AG Sbjct: 603 PPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAG 644 Score = 49.3 bits (116), Expect = 3e-06 Identities = 43/128 (33%), Positives = 49/128 (38%), Gaps = 25/128 (19%) Query: 87 PGSPDSVVPPPRSPDSVVPPPGSPDSVVLP--------PRSPDSVVPPPGSP---DSVVL 135 P +P S +PPP GSP + + P PD +PPP P D L Sbjct: 509 PHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPEL 568 Query: 136 PPRSPDSVVP-----PARSPDSGGRAGSPRSLAPPAAARAEGAPGWAGRWGRVP-LARSP 189 PP PD + P P P G AGS PP AP VP AR P Sbjct: 569 PPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAP--------VPDSARPP 620 Query: 190 PQVPSRPP 197 P V RPP Sbjct: 621 PAVAKRPP 628 Score = 41.6 bits (96), Expect = 5e-04 Identities = 30/78 (38%), Positives = 35/78 (44%), Gaps = 8/78 (10%) Query: 86 PPGSPDSVVPPPRSPDSVVPPPGSPDSVV---LPPRSPDSVVPPPGS-PDSVVLPPR-SP 140 PP PD + PPP D V PPP S + LPP P P P PDS PP + Sbjct: 569 PPPPPDFMEPPP---DFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAK 625 Query: 141 DSVVPPARSPDSGGRAGS 158 VPP R + G G+ Sbjct: 626 RPPVPPKRQENPGHPGGA 643 Score = 34.7 bits (78), Expect = 0.066 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 1/50 (2%) Query: 80 GAKVVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGS 129 G+++ PPP P + P P PDS PPP +PP+ ++ P G+ Sbjct: 595 GSELPPPPPPPPAPAPAP-VPDSARPPPAVAKRPPVPPKRQENPGHPGGA 643 Score = 33.9 bits (76), Expect = 0.11 Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 9/72 (12%) Query: 83 VVPPPGSPDSVVPPPRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPGSPDSVVLPPRSPDS 142 V PPP S + S +PPP P P PDS PPP +PP+ ++ Sbjct: 583 VPPPPPSYAGIA------GSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQEN 636 Query: 143 VVPPARSPDSGG 154 P +GG Sbjct: 637 ---PGHPGGAGG 645 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.132 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,264,552 Number of Sequences: 37866 Number of extensions: 938414 Number of successful extensions: 18336 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 466 Number of HSP's successfully gapped in prelim test: 1344 Number of HSP's that attempted gapping in prelim test: 6563 Number of HSP's gapped (non-prelim): 6917 length of query: 220 length of database: 18,247,518 effective HSP length: 98 effective length of query: 122 effective length of database: 14,536,650 effective search space: 1773471300 effective search space used: 1773471300 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.