BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|118600975 syntaxin binding protein 3 [Homo sapiens] (592 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|118600975 syntaxin binding protein 3 [Homo sapiens] 1195 0.0 gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens] 599 e-171 gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens] 586 e-167 gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens] 529 e-150 gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens] 521 e-148 gi|18105063 vacuolar protein sorting 45A [Homo sapiens] 118 1e-26 gi|33469966 vesicle transport-related protein isoform a [Homo sa... 76 1e-13 gi|33469978 vesicle transport-related protein isoform b [Homo sa... 62 2e-09 gi|18105056 vacuolar protein sorting 33A [Homo sapiens] 52 2e-06 gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 35 0.25 gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 33 0.96 gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 33 0.96 gi|31542785 sec1 family domain containing 2 [Homo sapiens] 33 0.96 gi|122937249 glutamate receptor interacting protein 2 [Homo sapi... 32 1.6 gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] 32 2.1 gi|55770834 centromere protein F [Homo sapiens] 31 2.8 gi|45505178 cancer antigen 1 [Homo sapiens] 31 3.7 gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange p... 30 4.8 gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 30 4.8 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 30 4.8 gi|71061468 centromere protein E [Homo sapiens] 30 4.8 gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 30 4.8 gi|171846278 leucine-rich repeat kinase 2 [Homo sapiens] 30 6.2 gi|4506467 radixin [Homo sapiens] 30 6.2 gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens] 30 6.2 gi|4758128 doublecortin-like kinase 1 [Homo sapiens] 30 6.2 gi|197209974 coiled-coil and C2 domain containing 2A isoform a [... 30 6.2 gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 30 8.2 gi|157384973 tenascin R [Homo sapiens] 30 8.2 gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 30 8.2 >gi|118600975 syntaxin binding protein 3 [Homo sapiens] Length = 592 Score = 1195 bits (3092), Expect = 0.0 Identities = 592/592 (100%), Positives = 592/592 (100%) Query: 1 MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGIT 60 MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGIT Sbjct: 1 MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGIT 60 Query: 61 VVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFN 120 VVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFN Sbjct: 61 VVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFN 120 Query: 121 KIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQ 180 KIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQ Sbjct: 121 KIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQ 180 Query: 181 IVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDR 240 IVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDR Sbjct: 181 IVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDR 240 Query: 241 GFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVV 300 GFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVV Sbjct: 241 GFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVV 300 Query: 301 LEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKL 360 LEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKL Sbjct: 301 LEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKL 360 Query: 361 NIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTE 420 NIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTE Sbjct: 361 NIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTE 420 Query: 421 ENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKD 480 ENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKD Sbjct: 421 ENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKD 480 Query: 481 IMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGIT 540 IMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGIT Sbjct: 481 IMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGIT 540 Query: 541 YSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE 592 YSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE Sbjct: 541 YSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE 592 >gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens] Length = 594 Score = 599 bits (1544), Expect = e-171 Identities = 309/599 (51%), Positives = 442/599 (73%), Gaps = 22/599 (3%) Query: 5 VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64 +A GLK+VV +KI V KK+GEWK++++D+ + ++L+SCCKMTD++ EGIT+VE+ Sbjct: 1 MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60 Query: 65 IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNK-IK 123 I K REP+ ++A+Y ITP+ KSV + DF KY+AA+++FTD CPD LFN+ +K Sbjct: 61 INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120 Query: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183 + +K I+ EINI+F+P+ESQVY+LD D+F YSP A+ K+ I+E +A+QI T Sbjct: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPH--KAQMKNPILERLAEQIAT 178 Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241 +CATL E P VRY+ + DNA LAQL++ KL D YK D+ ++ +G K SQLLI+DRG Sbjct: 179 LCATLKEYPAVRYRGEYKDNAL-LAQLIQDKL-DAYKADDPTMGEGPDKARSQLLILDRG 236 Query: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297 FDP S VLHELTFQAM+YDLLPIEND YKY+T G + KE +L+E+DDLW+ +RH+HI Sbjct: 237 FDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHI 296 Query: 298 AVVLEEIPKLMKEISSTKKATEG-KTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMN 356 A V +E+ + +K+ SS+K+ G KT++ L+Q++KKMP ++K+++K HL+LAEDCM Sbjct: 297 AEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMK 356 Query: 357 KFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSIN 416 ++ ++KLC+ EQDLA+GTDAEG+K+KD MR ++P+LL+ N DKIR ILLYIF N Sbjct: 357 HYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKN 416 Query: 417 GTTEENLDRLIQNVKIENE-SDMIRNWSYLGVPIVPQS---QQGKPLRKDRSAEETFQLS 472 G TEENL++LIQ+ +I E S++I N ++LGVPIV S ++ KP RK+R +E+T+QLS Sbjct: 417 GITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLS 476 Query: 473 RWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNG 528 RWTP IKDIMED I+++LD+K +PY S + + AVSAR K +A + ++G Sbjct: 477 RWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAP--GEYRSG 534 Query: 529 SKLIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVS 587 +LI+F++GG++ +E+RCAYEV+QA+ EV+IGSTH+LTP+KLLD +K LNK +++S Sbjct: 535 PRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQKLLDTLKKLNKTDEEIS 593 >gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens] Length = 603 Score = 586 bits (1511), Expect = e-167 Identities = 303/589 (51%), Positives = 433/589 (73%), Gaps = 22/589 (3%) Query: 5 VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64 +A GLK+VV +KI V KK+GEWK++++D+ + ++L+SCCKMTD++ EGIT+VE+ Sbjct: 1 MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60 Query: 65 IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNK-IK 123 I K REP+ ++A+Y ITP+ KSV + DF KY+AA+++FTD CPD LFN+ +K Sbjct: 61 INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120 Query: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183 + +K I+ EINI+F+P+ESQVY+LD D+F YSP A+ K+ I+E +A+QI T Sbjct: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPH--KAQMKNPILERLAEQIAT 178 Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241 +CATL E P VRY+ + DNA LAQL++ KL D YK D+ ++ +G K SQLLI+DRG Sbjct: 179 LCATLKEYPAVRYRGEYKDNAL-LAQLIQDKL-DAYKADDPTMGEGPDKARSQLLILDRG 236 Query: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297 FDP S VLHELTFQAM+YDLLPIEND YKY+T G + KE +L+E+DDLW+ +RH+HI Sbjct: 237 FDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHI 296 Query: 298 AVVLEEIPKLMKEISSTKKATEG-KTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMN 356 A V +E+ + +K+ SS+K+ G KT++ L+Q++KKMP ++K+++K HL+LAEDCM Sbjct: 297 AEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMK 356 Query: 357 KFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSIN 416 ++ ++KLC+ EQDLA+GTDAEG+K+KD MR ++P+LL+ N DKIR ILLYIF N Sbjct: 357 HYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKN 416 Query: 417 GTTEENLDRLIQNVKIENE-SDMIRNWSYLGVPIVPQS---QQGKPLRKDRSAEETFQLS 472 G TEENL++LIQ+ +I E S++I N ++LGVPIV S ++ KP RK+R +E+T+QLS Sbjct: 417 GITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLS 476 Query: 473 RWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNG 528 RWTP IKDIMED I+++LD+K +PY S + + AVSAR K +A + ++G Sbjct: 477 RWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAP--GEYRSG 534 Query: 529 SKLIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIK 577 +LI+F++GG++ +E+RCAYEV+QA+ EV+IGSTH+LTP K L D++ Sbjct: 535 PRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLR 583 >gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens] Length = 593 Score = 529 bits (1362), Expect = e-150 Identities = 277/598 (46%), Positives = 407/598 (68%), Gaps = 20/598 (3%) Query: 5 VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64 +A GLK+VV +KI + V KK+GEWK++++D + ++L+SCCKM+D+L EGIT+VE+ Sbjct: 1 MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVED 60 Query: 65 IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKI-K 123 I K REP+ ++A+Y ++PT KSV + DF YKAA+I+FTD CP+ LF+++ + Sbjct: 61 INKRREPIPSLEAIYLLSPTEKSVQALIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGR 120 Query: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183 + +K ++ KEI+++F+P+E+QV++LD P + Y Y P A+ + +E +A QI T Sbjct: 121 SRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPF--RAEERTRQLEVLAQQIAT 178 Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241 +CATL E P +RY+ P D A +LA V KL + +K D SL +G KT SQLLI+DR Sbjct: 179 LCATLQEYPAIRYRKGPEDTA-QLAHAVLAKL-NAFKADTPSLGEGPEKTRSQLLIMDRA 236 Query: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297 DPVS +LHELTFQAMAYDLL IE DTY+Y+T G +EK +L+E+DDLWV +RH HI Sbjct: 237 ADPVSPLLHELTFQAMAYDLLDIEQDTYRYETTGLSEAREKAVLLDEDDDLWVELRHMHI 296 Query: 298 AVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNK 357 A V +++ +L++ +K+ T K ++ L+Q++KKMP ++K++ K HL+LA+DCM Sbjct: 297 ADVSKKVTELLRTFCESKRLTTDKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKH 356 Query: 358 FKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSING 417 FK ++EKLC EQDLA+G+DAEG+K+KDSM++++PVLL+ DKIR +LLYI NG Sbjct: 357 FKGSVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNG 416 Query: 418 TTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKD--RSAEETFQLSRWT 475 +EENL +LIQ+ ++ S +IRN LG + G R + E T+QLSRWT Sbjct: 417 VSEENLAKLIQHANVQAHSSLIRNLEQLGGTVTNPGGSGTSSRLEPRERMEPTYQLSRWT 476 Query: 476 PFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNGSKL 531 P IKD+MEDA+++RLD WP+ S + AVSAR K +A + + G +L Sbjct: 477 PVIKDVMEDAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGI--EARAGPRL 534 Query: 532 IVFVIGGITYSEVRCAYEVSQAHK-SCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSL 588 IV+V+GG+ SE+R AYEV++A + EV+IGS+H+LTP + LDD+K L+K + ++L Sbjct: 535 IVYVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALDKKLEDIAL 592 >gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens] Length = 590 Score = 521 bits (1342), Expect = e-148 Identities = 275/598 (45%), Positives = 407/598 (68%), Gaps = 23/598 (3%) Query: 5 VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64 +A GLK+VV +KI + V KK+GEWK++++D + ++L+SCCKM+D+L EGIT+VE+ Sbjct: 1 MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVED 60 Query: 65 IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKI-K 123 I K REP+ ++A+Y ++PT K++ + DF YKAA+I+FTD CP+ LF+++ + Sbjct: 61 INKRREPIPSLEAIYLLSPTEKAL---IKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGR 117 Query: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183 + +K ++ KEI+++F+P+E+QV++LD P + Y Y P A+ + +E +A QI T Sbjct: 118 SRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPF--RAEERTRQLEVLAQQIAT 175 Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241 +CATL E P +RY+ P D A +LA V KL + +K D SL +G KT SQLLI+DR Sbjct: 176 LCATLQEYPAIRYRKGPEDTA-QLAHAVLAKL-NAFKADTPSLGEGPEKTRSQLLIMDRA 233 Query: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297 DPVS +LHELTFQAMAYDLL IE DTY+Y+T G +EK +L+E+DDLWV +RH HI Sbjct: 234 ADPVSPLLHELTFQAMAYDLLDIEQDTYRYETTGLSEAREKAVLLDEDDDLWVELRHMHI 293 Query: 298 AVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNK 357 A V +++ +L++ +K+ T K ++ L+Q++KKMP ++K++ K HL+LA+DCM Sbjct: 294 ADVSKKVTELLRTFCESKRLTTDKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKH 353 Query: 358 FKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSING 417 FK ++EKLC EQDLA+G+DAEG+K+KDSM++++PVLL+ DKIR +LLYI NG Sbjct: 354 FKGSVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNG 413 Query: 418 TTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKD--RSAEETFQLSRWT 475 +EENL +LIQ+ ++ S +IRN LG + G R + E T+QLSRWT Sbjct: 414 VSEENLAKLIQHANVQAHSSLIRNLEQLGGTVTNPGGSGTSSRLEPRERMEPTYQLSRWT 473 Query: 476 PFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNGSKL 531 P IKD+MEDA+++RLD WP+ S + AVSAR K +A + + G +L Sbjct: 474 PVIKDVMEDAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGI--EARAGPRL 531 Query: 532 IVFVIGGITYSEVRCAYEVSQAHK-SCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSL 588 IV+V+GG+ SE+R AYEV++A + EV+IGS+H+LTP + LDD+K L+K + ++L Sbjct: 532 IVYVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALDKKLEDIAL 589 >gi|18105063 vacuolar protein sorting 45A [Homo sapiens] Length = 570 Score = 118 bits (296), Expect = 1e-26 Identities = 118/568 (20%), Positives = 253/568 (44%), Gaps = 67/568 (11%) Query: 33 KIMLLDEFTTKLLASCCKMTDLLEEGITVVENI-YKNREPVRQMKALYFITPTSKSVDCF 91 K++L+D+ TT +++ +++L++ + + E I +NRE ++ +KA+ F+ PT ++VD Sbjct: 23 KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYI 82 Query: 92 LHDFASKSENKYKAAYIYFTD-FCPDNLFNKIKASCSKSIRRCKEINISFIPHESQVYTL 150 + + KY +IYF++ ++ + +A + + +E +I +++L Sbjct: 83 IQELRRP---KYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSL 139 Query: 151 DVPDAFYYCYSPDPGNAKGKD---AIMETMADQIVTVCATLDENPGVRYKSKPLDNASKL 207 ++ G +G++ A + + + +L + P +RY+ + A +L Sbjct: 140 NIL-----------GCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSS-EAAKRL 187 Query: 208 AQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIEN- 266 A+ V++ + Y++ E + + LLI+DR D ++ +L++ T+QAM ++LL I N Sbjct: 188 AECVKQVITKEYELFE--FRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNN 245 Query: 267 --DTYKYKTDGKE-KEAILE-EEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKT 322 D + K+ +E +L E D+ + + + A + I LM++ K + K Sbjct: 246 RIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKL 305 Query: 323 -SLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKF-KLNIEKLCKTEQDLALGTDAEG 380 S++ + ++ P F+K H+ + + + N+ ++ + EQ+LA D Sbjct: 306 ESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSS 365 Query: 381 QKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIENESDMIR 440 +++ + +L N D R ++LY + +L L+ +++ + S+ R Sbjct: 366 -----ALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYR 420 Query: 441 NWSYLGVPIVPQSQQGKPLRKDRSAEETFQ------------LSRWTPFIKDIMEDAIDN 488 V + +G L + A + ++ PF+ + ++ I Sbjct: 421 KLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG 480 Query: 489 RLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRCAY 548 RL +PY G + R +P+ +IVFVIGG TY E Y Sbjct: 481 RLKENLYPYL----------GPSTLRDRPQ-----------DIIVFVIGGATYEEALTVY 519 Query: 549 EVSQAHKSCEVIIGSTHVLTPKKLLDDI 576 +++ +++G T V K L+++ Sbjct: 520 NLNRTTPGVRIVLGGTTVHNTKSFLEEV 547 >gi|33469966 vesicle transport-related protein isoform a [Homo sapiens] Length = 642 Score = 75.9 bits (185), Expect = 1e-13 Identities = 88/425 (20%), Positives = 171/425 (40%), Gaps = 68/425 (16%) Query: 29 EGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYKNREPVRQMKALYFITPTSKSV 88 E WK+++ D F +++ + +L + GIT+ ++ +R+P+ + A+YF+ PT +++ Sbjct: 40 EPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENI 99 Query: 89 DCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKI-----KASCSKSIRRCKEINISFIPH 143 D D ++ Y++ Y+ F + I AS + + + ++FI Sbjct: 100 DRMCQDLRNQ---LYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITL 156 Query: 144 ESQVYTLDVPDAFYYCY----SPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSK 199 E ++ L + Y PD + + + +M+T+ D + TL P +R Sbjct: 157 EDDMFVLCNQNKELVSYRAINRPDITDTE-METVMDTIVDSLFCFFVTLGAVPIIRCSRG 215 Query: 200 PLDNASKLAQLVEKKLEDYYKIDEKSLIKGKT---------HSQLLIIDRGFDPVSTVLH 250 A +A ++KKL + + SL G T L+++DR D + + H Sbjct: 216 TA--AEMVAVKLDKKLRENLRDARNSLFTGDTLGAGQFSFQRPLLVLVDRNIDLATPLHH 273 Query: 251 ELTFQAMAYDLLP-------------IENDTYKYKTDGKEKEAI-LEEEDDLWVRIRHRH 296 T+QA+ +D+L +EN + K K++ L D W + + Sbjct: 274 TWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSP 333 Query: 297 IAVVLEEIP-------------KLMKEISSTKKATEGKTSL-----SALTQLMKKMPHFR 338 V E + K +K I + EG S+ + LT + +P Sbjct: 334 FPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELL 393 Query: 339 KQITKQVVHLNLAEDCMNK---------FKLNIEKLCKTEQD---LALGTDAEGQKVKDS 386 ++ +H N+A + F+ + + KT D L + +D + +D Sbjct: 394 EKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDIISDPDAGTPEDK 453 Query: 387 MRVLL 391 MR+ L Sbjct: 454 MRLFL 458 >gi|33469978 vesicle transport-related protein isoform b [Homo sapiens] Length = 575 Score = 61.6 bits (148), Expect = 2e-09 Identities = 82/396 (20%), Positives = 156/396 (39%), Gaps = 68/396 (17%) Query: 58 GITVVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDN 117 GIT+ ++ +R+P+ + A+YF+ PT +++D D ++ Y++ Y+ F + Sbjct: 2 GITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQ---LYESYYLNFISAISRS 58 Query: 118 LFNKI-----KASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCY----SPDPGNAK 168 I AS + + + ++FI E ++ L + Y PD + + Sbjct: 59 KLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTE 118 Query: 169 GKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIK 228 + +M+T+ D + TL P +R A +A ++KKL + + SL Sbjct: 119 -METVMDTIVDSLFCFFVTLGAVPIIRCSRGTA--AEMVAVKLDKKLRENLRDARNSLFT 175 Query: 229 GKT---------HSQLLIIDRGFDPVSTVLHELTFQAMAYDLLP-------------IEN 266 G T L+++DR D + + H T+QA+ +D+L +EN Sbjct: 176 GDTLGAGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVEN 235 Query: 267 DTYKYKTDGKEKEAI-LEEEDDLWVRIRHRHIAVVLEEIP-------------KLMKEIS 312 + K K++ L D W + + V E + K +K I Sbjct: 236 SPAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIM 295 Query: 313 STKKATEGKTSL-----SALTQLMKKMPHFRKQITKQVVHLNLAEDCMNK---------F 358 + EG S+ + LT + +P ++ +H N+A + F Sbjct: 296 GLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYF 355 Query: 359 KLNIEKLCKTEQD---LALGTDAEGQKVKDSMRVLL 391 + + + KT D L + +D + +D MR+ L Sbjct: 356 EYEEKIMSKTTLDKSLLDIISDPDAGTPEDKMRLFL 391 >gi|18105056 vacuolar protein sorting 33A [Homo sapiens] Length = 596 Score = 52.0 bits (123), Expect = 2e-06 Identities = 104/598 (17%), Positives = 225/598 (37%), Gaps = 82/598 (13%) Query: 33 KIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYKNREPVRQMK-ALYFITPTSKSVDCF 91 K ++ DE+ T + + L E + + + NR P +K ++F+ P + +D Sbjct: 34 KAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGNRLPAADVKNIIFFVRPRLELMDII 93 Query: 92 LHDFASKSEN-KYKAAYIYFTD----FCPDNLFNKIKASCSKSIRRCKEINISFIPHESQ 146 + S+ + +I F C L K I R +E ++ IP + Sbjct: 94 AENVLSEDRRGPTRDFHILFVPRRSLLCEQRL--KDLGVLGSFIHR-EEYSLDLIPFDGD 150 Query: 147 VYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASK 206 + +++ AF CY +G + A ++T+ A P + K + + Sbjct: 151 LLSMESEGAFKECY------LEGDQTSLYHAAKGLMTLQALYGTIPQIFGKGECARQVAN 204 Query: 207 LAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAM--------- 257 + ++ K E + + S+ LL++DR D ++ + +LT++ + Sbjct: 205 M--MIRMKRE--FTGSQNSIFP--VFDNLLLLDRNVDLLTPLATQLTYEGLIDEIYGIQN 258 Query: 258 AYDLLPIENDTYKYKTDG------KEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEI 311 +Y LP E K + DG + K+ L ++L+ IR ++ V + K K I Sbjct: 259 SYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKII 318 Query: 312 SSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAE--DCMNKFKLNIEKLCKTE 369 S+ + ++ + Q + ++PH + H ++AE + + +KL E Sbjct: 319 SAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDVTTSEDFFDKL-TVE 377 Query: 370 QDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQN 429 Q+ G D D + + + + H +R + L +G ++ LD Sbjct: 378 QEFMSGIDT------DKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGLKQKVLDYY--- 428 Query: 430 VKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNR 489 + ++++ + Y + + ++ L+ + R T ++ M+D + Sbjct: 429 -----KREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKT--LRLWMDDVNEQN 481 Query: 490 LDSKEWPYCSQCPAV-----------WNG--------SGAVSARQKPRANYLEDRKNGSK 530 + Y P W G ++P L+ ++ + Sbjct: 482 PTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPGE 541 Query: 531 ---LIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDK 585 ++F +GG+T++E+ +SQ G+ +V+ KL++ + +K Sbjct: 542 NRVTLIFFLGGVTFAEIAALRFLSQLEDG-----GTEYVIATTKLMNGTSWIEALMEK 594 >gi|154354990 ankyrin repeat domain 26 [Homo sapiens] Length = 1710 Score = 34.7 bits (78), Expect = 0.25 Identities = 53/246 (21%), Positives = 106/246 (43%), Gaps = 35/246 (14%) Query: 201 LDNASKLAQLVEK---KLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAM 257 LD+A A EK ++D + + L LL+ +R + +S H Sbjct: 1150 LDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNH------- 1202 Query: 258 AYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKA 317 ++ Y+Y+ + E+E + VR + +A L++ + M E +S + Sbjct: 1203 ------LKERQYQYENEKAEREVV--------VRQLQQELADTLKK--QSMSE-ASLEVT 1245 Query: 318 TEGKTSLSALTQ-LMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGT 376 + + +L TQ L KK+ R Q+ + A C K + + +KL K L + Sbjct: 1246 SRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTV 1305 Query: 377 DAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDR-LIQNVKIENE 435 + K+++ + LL N + D ++++ ++ + + E NLD+ + +NV++E E Sbjct: 1306 KKQMDKIEELQKNLLNA--NLSEDEKEQLKKLM----ELKQSLECNLDQEMKKNVELERE 1359 Query: 436 SDMIRN 441 +N Sbjct: 1360 ITGFKN 1365 >gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] Length = 3907 Score = 32.7 bits (73), Expect = 0.96 Identities = 66/301 (21%), Positives = 124/301 (41%), Gaps = 42/301 (13%) Query: 274 DGKEKEAILEEEDDLWVRIRHRHIAVVLEEIP-KLMKEISSTKKATEGKTSLSALTQLMK 332 + KEK +ILE+ED+ ++ A + E +P KL K I+S T+G +S+ Q + Sbjct: 2742 EAKEKLSILEKEDE--TEVQESKKACMFEPLPIKLSKSIAS---QTDGTLKISSSNQTPQ 2796 Query: 333 KMPHFRKQITKQVVHLNLAEDC--------MNKFKLNIEKLCKTEQDLALGTDAEGQKVK 384 + + + +NL +C +++F IEK+ + L ++ Sbjct: 2797 IL------VKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISET 2850 Query: 385 DSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRL-IQNVKIENESDMIRNWS 443 ++++ V + + C ++A++ + S G++ L + SD +W Sbjct: 2851 ETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTREICSSDSGSDW- 2909 Query: 444 YLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTP-FIKDIMEDAIDNR----LDSKEWPYC 498 G I QG + + EE+ + P IK ++ A+ N L E PY Sbjct: 2910 --GQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLR-AVHNEGMQVLSLTESPY- 2965 Query: 499 SQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRC---AYEVSQAHK 555 G + Q+ +LE+RK I + IT +++ Y+ SQ+H+ Sbjct: 2966 --------SDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHE 3017 Query: 556 S 556 S Sbjct: 3018 S 3018 >gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] Length = 3899 Score = 32.7 bits (73), Expect = 0.96 Identities = 66/301 (21%), Positives = 124/301 (41%), Gaps = 42/301 (13%) Query: 274 DGKEKEAILEEEDDLWVRIRHRHIAVVLEEIP-KLMKEISSTKKATEGKTSLSALTQLMK 332 + KEK +ILE+ED+ ++ A + E +P KL K I+S T+G +S+ Q + Sbjct: 2734 EAKEKLSILEKEDE--TEVQESKKACMFEPLPIKLSKSIAS---QTDGTLKISSSNQTPQ 2788 Query: 333 KMPHFRKQITKQVVHLNLAEDC--------MNKFKLNIEKLCKTEQDLALGTDAEGQKVK 384 + + + +NL +C +++F IEK+ + L ++ Sbjct: 2789 IL------VKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISET 2842 Query: 385 DSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRL-IQNVKIENESDMIRNWS 443 ++++ V + + C ++A++ + S G++ L + SD +W Sbjct: 2843 ETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTREICSSDSGSDW- 2901 Query: 444 YLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTP-FIKDIMEDAIDNR----LDSKEWPYC 498 G I QG + + EE+ + P IK ++ A+ N L E PY Sbjct: 2902 --GQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLR-AVHNEGMQVLSLTESPY- 2957 Query: 499 SQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRC---AYEVSQAHK 555 G + Q+ +LE+RK I + IT +++ Y+ SQ+H+ Sbjct: 2958 --------SDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHE 3009 Query: 556 S 556 S Sbjct: 3010 S 3010 >gi|31542785 sec1 family domain containing 2 [Homo sapiens] Length = 684 Score = 32.7 bits (73), Expect = 0.96 Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%) Query: 531 LIVFVIGGITYSEVRCAYE-VSQAHKSCEVIIGSTHVLTP 569 LI+FV+GG+T SEV+ + V+ +VI+ ST +L P Sbjct: 626 LILFVVGGVTVSEVKMVKDLVASLKPGTQVIVLSTRLLKP 665 >gi|122937249 glutamate receptor interacting protein 2 [Homo sapiens] Length = 1141 Score = 32.0 bits (71), Expect = 1.6 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 9/71 (12%) Query: 411 YIFSINGTTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSA---EE 467 +I SI+GT+ E+ L + + S+ +R L + VPQSQ +PLR R + Sbjct: 393 HILSIDGTSMEHCSLLEATKLLASISEKVR----LEILPVPQSQ--RPLRPQRQVVKVQR 446 Query: 468 TFQLSRWTPFI 478 + QL RW P + Sbjct: 447 SEQLHRWDPCV 457 >gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] Length = 1247 Score = 31.6 bits (70), Expect = 2.1 Identities = 33/138 (23%), Positives = 58/138 (42%), Gaps = 7/138 (5%) Query: 360 LNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTT 419 L I K E++ + D GQK+ + + K H K + IF ++ + Sbjct: 357 LMILKAILLEENNLIPVDQLGQKLLKKIGISWNKKYRKQHGPLRKFLQLHSQIFLLS--S 414 Query: 420 EENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIK 479 +E+ RL++N ++ ESD RN + + P+S L S F ++ ++ Sbjct: 415 DESTVRLLKNSSLQAESDFQRNDQQIFKMLPPES---PGLNNSISCPHWFDIN--DSKVQ 469 Query: 480 DIMEDAIDNRLDSKEWPY 497 I E I+ + KE Y Sbjct: 470 PIREKDIEQQFQGKESAY 487 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 31.2 bits (69), Expect = 2.8 Identities = 37/177 (20%), Positives = 81/177 (45%), Gaps = 18/177 (10%) Query: 265 ENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKTSL 324 END+ K K + E+E + EE+ V + + +E + ++E++ + K E Sbjct: 2148 ENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFE----- 2202 Query: 325 SALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQKVK 384 L L + + KQI ++ L+ + ++ FK +E+ K + ++ ++K Sbjct: 2203 LDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEE--KEQAEI---------QIK 2251 Query: 385 DSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNV-KIENESDMIR 440 + + + +L N+ + + + A L I TE++LD I+ ++ N + +R Sbjct: 2252 EESKTAVEMLQNQLKELNEAV-AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLR 2307 >gi|45505178 cancer antigen 1 [Homo sapiens] Length = 641 Score = 30.8 bits (68), Expect = 3.7 Identities = 71/394 (18%), Positives = 155/394 (39%), Gaps = 65/394 (16%) Query: 201 LDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYD 260 +D +KL + VE+ +ED YKI +L + + + Sbjct: 215 IDVINKLKENVEELIEDKYKI--------------------------ILEKNDTKKTLQN 248 Query: 261 LLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEG 320 L + +T K+ + + + +L+ + + +I+ ++ + + ++ ++ S + E Sbjct: 249 LEEVLANTQKHLQESRNDKEMLQLQ---FKKIKANYVCLQERYMTEMQQKNKSVSQYLEM 305 Query: 321 KTSLSALTQLMKKMPHFRKQITKQVVH-LNLAEDCMNKFKLNIEKLCKTEQDLALGTDAE 379 +LS + ++++ +K++ K L+L + + L + Q L E Sbjct: 306 DKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEE 365 Query: 380 GQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIENESDMI 439 QK+K + LL + N L S N T +N+K++ + + + Sbjct: 366 RQKLKSRLEKLLTQVRN-------------LQFMSENERT--------KNIKLQQQINEV 404 Query: 440 RNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCS 499 +N + V +S++ + K +A+ QL DI +D S P CS Sbjct: 405 KNENAKLKQQVARSEEQNYVPKFETAQLKDQLEE--VLKSDITKDT--KTTHSNLLPDCS 460 Query: 500 QCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEV--RCAYEVSQAHKSC 557 C N + RA+ L + + L+ ++G +T ++ A ++ K Sbjct: 461 PCEERLNPADI------KRASQLASKMH--SLLALMVGLLTCQDIINSDAEHFKESEKVS 512 Query: 558 EVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKD 591 ++++ L KK D ++++ D+ I+D Sbjct: 513 DIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRD 546 Score = 29.6 bits (65), Expect = 8.2 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 9/98 (9%) Query: 299 VVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKF 358 + L E+ + +K + ++ + S L L K++ + +ITKQ V + D +NK Sbjct: 167 MALNEVLQKLKHTNRKQEVRIQELQCSNL-YLEKRVKELQMKITKQQVFI----DVINKL 221 Query: 359 KLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLN 396 K N+E+L + + + L E K +++ L VL N Sbjct: 222 KENVEELIEDKYKIIL----EKNDTKKTLQNLEEVLAN 255 >gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange protein 3 [Homo sapiens] Length = 2177 Score = 30.4 bits (67), Expect = 4.8 Identities = 34/134 (25%), Positives = 64/134 (47%), Gaps = 20/134 (14%) Query: 302 EEIPKLMKEISSTK------KATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCM 355 E + KL KE S +K T +L L ++K PH ++ K ++ L LA + Sbjct: 3 EILRKLQKEASGSKYKAIKESCTWALETLGGLDTIVKIPPHVLRE--KCLLPLQLALESK 60 Query: 356 NKFKL------NIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAIL 409 N KL ++KL E+ +++ TD++ +++ + + + V + N D ++ +L Sbjct: 61 N-VKLAQHALAGMQKLLSEERFVSMETDSDEKQLLNQILNAVKVTPSLNEDLQVEVMKVL 119 Query: 410 LYI-----FSINGT 418 L I F +NG+ Sbjct: 120 LCITYTPTFDLNGS 133 >gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] Length = 1217 Score = 30.4 bits (67), Expect = 4.8 Identities = 32/148 (21%), Positives = 60/148 (40%), Gaps = 34/148 (22%) Query: 212 EKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIENDTYKY 271 EK LE Y K+D+ + +++ +DR + V EL + Y + Sbjct: 428 EKNLEQYNKLDQDL---NEVKARVEELDRKYYEVKNKKDELQSER-----------NYLW 473 Query: 272 KTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLM 331 + + E++A+ + +DL E+ +L++ A GK L+ + + Sbjct: 474 REENAEQQALAAKREDL-------------EKKQQLLR-------AATGKAILNGIDSIN 513 Query: 332 KKMPHFRKQITKQVVHLNLAEDCMNKFK 359 K + HFR++ Q V MN F+ Sbjct: 514 KVLDHFRRKGINQHVQNGYHGIVMNNFE 541 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 30.4 bits (67), Expect = 4.8 Identities = 37/202 (18%), Positives = 89/202 (44%), Gaps = 25/202 (12%) Query: 189 DENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTV 248 ++ G++++ K + +++ +L E+ I+ + + KT Q R + +S Sbjct: 1098 EQTLGLQFQKKIKELQARIEELEEE-------IEAERATRAKTEKQRSDYARELEELSER 1150 Query: 249 LHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLM 308 L E L + + K +EA L+ E + +R +H + + +L Sbjct: 1151 LEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEA-MVAALRKKHA----DSVAELG 1205 Query: 309 KEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKT 368 ++I + ++ + +L K+ F+ +I L+ + + ++K K N+EK+C+T Sbjct: 1206 EQIDNLQRVKQ---------KLEKEKSEFKLEIDD----LSSSMESVSKSKANLEKICRT 1252 Query: 369 EQDLALGTDAEGQKVKDSMRVL 390 +D + ++++ S+ L Sbjct: 1253 LEDQLSEARGKNEEIQRSLSEL 1274 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 30.4 bits (67), Expect = 4.8 Identities = 52/325 (16%), Positives = 134/325 (41%), Gaps = 44/325 (13%) Query: 199 KPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMA 258 K D K Q ++KK ++ E + K +++ + + F+ L+ Q++ Sbjct: 1963 KSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEA-----QNLSMQSVR 2017 Query: 259 YDLLPIENDTYKYKTD----GKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISST 314 D + ++ + KE++ + ++ L + R + IA + E I + + Sbjct: 2018 MDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKME-RDQFIATLREMIARDRQNHQVK 2076 Query: 315 KKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLAL 374 + LT+ +++ K++ K+ ++ +C+N+ L++EK + +++L++ Sbjct: 2077 PEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSM 2136 Query: 375 GTDAEGQKVKDSMRVLLPVLLNKN---------------HDNCDKIRAILLYIFSINGTT 419 A + LP L K+ H K++ +L Y+ I Sbjct: 2137 RVKA---------NLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQ 2187 Query: 420 EENLDRLIQNV--KIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAE-------ETFQ 470 E++++ + ++E + +++ +L S++ + L+ +++ + + F Sbjct: 2188 HESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFS 2247 Query: 471 LSRWTPFIKDIMEDAIDNRLDSKEW 495 S + P IK + + NR + ++ Sbjct: 2248 ESEF-PSIKTEFQQVLSNRKEMTQF 2271 >gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] Length = 1417 Score = 30.4 bits (67), Expect = 4.8 Identities = 35/187 (18%), Positives = 76/187 (40%), Gaps = 27/187 (14%) Query: 203 NASKLAQLVEKKLEDYYKIDEKSLIKG----KTHSQLLIIDRGFDPVSTVLHELTFQ--- 255 N K + ++KK E+ Y + ++ IK +T Q +I+ +L + T + Sbjct: 868 NKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGE 927 Query: 256 ------AMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMK 309 + + +E + K + EK +EE+ + + E K K Sbjct: 928 LEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE----------SAAHEADLKRQK 977 Query: 310 EISSTKKATEGKTSLSA----LTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKL 365 I T A + K + L+++ K++ H ++ + +HL+ + +++ K +EK Sbjct: 978 VIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKK 1037 Query: 366 CKTEQDL 372 ++L Sbjct: 1038 TNAVKEL 1044 >gi|171846278 leucine-rich repeat kinase 2 [Homo sapiens] Length = 2527 Score = 30.0 bits (66), Expect = 6.2 Identities = 35/121 (28%), Positives = 60/121 (49%), Gaps = 19/121 (15%) Query: 312 SSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLN---IEKLCKT 368 SS+K+ + S +AL+ L+++ +FRK + + +HLN+ E M K + E CK Sbjct: 409 SSSKEVFQA--SANALSTLLEQNVNFRKILLSKGIHLNVLE-LMQKHIHSPEVAESGCKM 465 Query: 369 EQDLALGTDAEGQKVKDSMRVLLPVLLN--KNHD-----NCDKIRAILLYIFSINGTTEE 421 L G++ D M ++P +L K H+ + +RAIL +I + G EE Sbjct: 466 LNHLFEGSNTS----LDIMAAVVPKILTVMKRHETSLPVQLEALRAILHFI--VPGMPEE 519 Query: 422 N 422 + Sbjct: 520 S 520 >gi|4506467 radixin [Homo sapiens] Length = 583 Score = 30.0 bits (66), Expect = 6.2 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 9/126 (7%) Query: 264 IENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEI-SSTKKATEGKT 322 +EN+ K + KEKE I E+++L R++ + E+ K KE+ T+KA E Sbjct: 323 LENEKKKREIAEKEKERIEREKEELMERLKQ-----IEEQTIKAQKELEEQTRKALELDQ 377 Query: 323 SLSALTQLMKKMPHFRK--QITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEG 380 + +++ R+ + K + A+ N+ +L E L + +AL +A+ Sbjct: 378 ERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAE-LAEFTAKIALLEEAKK 436 Query: 381 QKVKDS 386 +K +++ Sbjct: 437 KKEEEA 442 >gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens] Length = 222 Score = 30.0 bits (66), Expect = 6.2 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 3/95 (3%) Query: 166 NAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKS 225 N GKD + + D + A L E + S+P + +KLA + EK Y+ EK Sbjct: 80 NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKV 139 Query: 226 LIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYD 260 L K+H Q ++ L EL + D Sbjct: 140 L---KSHGQDYLVGNKLSRADIHLVELLYYVEELD 171 >gi|4758128 doublecortin-like kinase 1 [Homo sapiens] Length = 729 Score = 30.0 bits (66), Expect = 6.2 Identities = 35/155 (22%), Positives = 63/155 (40%), Gaps = 41/155 (26%) Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFD 243 VC+++DEN G P + S+ + + + YK+ G+T I D F Sbjct: 361 VCSSMDENDG------PGEEVSEEGFQIPATITERYKV-------GRT-----IGDGNFA 402 Query: 244 PVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEE 303 V + T + A ++ K+ + KE +++ E + R++H +I +++EE Sbjct: 403 VVKECVERSTAREYALKIIK--------KSKCRGKEHMIQNEVSILRRVKHPNIVLLIEE 454 Query: 304 IP---------------KLMKEISSTKKATEGKTS 323 + L I+ST K TE S Sbjct: 455 MDVPTELYLVMELVKGGDLFDAITSTNKYTERDAS 489 >gi|197209974 coiled-coil and C2 domain containing 2A isoform a [Homo sapiens] Length = 1620 Score = 30.0 bits (66), Expect = 6.2 Identities = 17/74 (22%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Query: 212 EKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLP--IENDTY 269 + +++ +KID ++ G + + +I++RGFD V + L E ++ + + P + ++ Sbjct: 1196 QARIDGTFKIDIPPVLLGYSKERNMILERGFDSVRS-LSEGSYITLFITIEPQLVPGESI 1254 Query: 270 KYKTDGKEKEAILE 283 + K + +E E +L+ Sbjct: 1255 REKFESQEDEKLLQ 1268 >gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] Length = 789 Score = 29.6 bits (65), Expect = 8.2 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 6/68 (8%) Query: 451 PQSQQGKPLRKDRSAEETFQLSRWTPFIKDI-MEDAIDNRL-----DSKEWPYCSQCPAV 504 P++++ LR+D E FQ+ R P ++I ++D I RL D PY S Sbjct: 680 PEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRLKENDADPSAPPYDSLATYA 739 Query: 505 WNGSGAVS 512 + G+ +++ Sbjct: 740 YEGNDSIA 747 >gi|157384973 tenascin R [Homo sapiens] Length = 1358 Score = 29.6 bits (65), Expect = 8.2 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 6/54 (11%) Query: 244 PVSTVLHELTFQAMAYDLLP----IENDTYKYK-TDGKEKEAILEEEDDLWVRI 292 P + E+T Q+ P IEN YK TDG KE I++ E D W+R+ Sbjct: 1044 PANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAE-DTWIRL 1096 >gi|29294627 PTPRF interacting protein binding protein 1 isoform 1 [Homo sapiens] Length = 1005 Score = 29.6 bits (65), Expect = 8.2 Identities = 28/135 (20%), Positives = 63/135 (46%), Gaps = 9/135 (6%) Query: 261 LLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEE--IPKLMKEISSTKKAT 318 L +E D Y+ ++ E +++E +DL +++ + E + E++S K+ Sbjct: 183 LTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQL 242 Query: 319 EGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFK---LNIEKLCKTEQDLALG 375 E K S + +L +K+ K ++V + E+ K K + ++K+ K + L Sbjct: 243 EEKE--SEVKRLQEKLVCKMKGEGVEIVDRD--ENFKKKLKEKNIEVQKMKKAVESLMAA 298 Query: 376 TDAEGQKVKDSMRVL 390 + + +K++D + L Sbjct: 299 NEEKDRKIEDLRQCL 313 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,720,700 Number of Sequences: 37866 Number of extensions: 929729 Number of successful extensions: 2513 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 2450 Number of HSP's gapped (non-prelim): 43 length of query: 592 length of database: 18,247,518 effective HSP length: 108 effective length of query: 484 effective length of database: 14,157,990 effective search space: 6852467160 effective search space used: 6852467160 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.