Guide to the Human Genome
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Search of human proteins with 118600975

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118600975 syntaxin binding protein 3 [Homo sapiens]
         (592 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118600975 syntaxin binding protein 3 [Homo sapiens]               1195   0.0  
gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens]       599   e-171
gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]        586   e-167
gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens]      529   e-150
gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens]      521   e-148
gi|18105063 vacuolar protein sorting 45A [Homo sapiens]               118   1e-26
gi|33469966 vesicle transport-related protein isoform a [Homo sa...    76   1e-13
gi|33469978 vesicle transport-related protein isoform b [Homo sa...    62   2e-09
gi|18105056 vacuolar protein sorting 33A [Homo sapiens]                52   2e-06
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                   35   0.25 
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         33   0.96 
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         33   0.96 
gi|31542785 sec1 family domain containing 2 [Homo sapiens]             33   0.96 
gi|122937249 glutamate receptor interacting protein 2 [Homo sapi...    32   1.6  
gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]                   32   2.1  
gi|55770834 centromere protein F [Homo sapiens]                        31   2.8  
gi|45505178 cancer antigen 1 [Homo sapiens]                            31   3.7  
gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange p...    30   4.8  
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]      30   4.8  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    30   4.8  
gi|71061468 centromere protein E [Homo sapiens]                        30   4.8  
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   30   4.8  
gi|171846278 leucine-rich repeat kinase 2 [Homo sapiens]               30   6.2  
gi|4506467 radixin [Homo sapiens]                                      30   6.2  
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]          30   6.2  
gi|4758128 doublecortin-like kinase 1 [Homo sapiens]                   30   6.2  
gi|197209974 coiled-coil and C2 domain containing 2A isoform a [...    30   6.2  
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]            30   8.2  
gi|157384973 tenascin R [Homo sapiens]                                 30   8.2  
gi|29294627 PTPRF interacting protein binding protein 1 isoform ...    30   8.2  

>gi|118600975 syntaxin binding protein 3 [Homo sapiens]
          Length = 592

 Score = 1195 bits (3092), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGIT 60
           MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGIT
Sbjct: 1   MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGIT 60

Query: 61  VVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFN 120
           VVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFN
Sbjct: 61  VVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFN 120

Query: 121 KIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQ 180
           KIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQ
Sbjct: 121 KIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQ 180

Query: 181 IVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDR 240
           IVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDR
Sbjct: 181 IVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDR 240

Query: 241 GFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVV 300
           GFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVV
Sbjct: 241 GFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVV 300

Query: 301 LEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKL 360
           LEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKL
Sbjct: 301 LEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKL 360

Query: 361 NIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTE 420
           NIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTE
Sbjct: 361 NIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTE 420

Query: 421 ENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKD 480
           ENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKD
Sbjct: 421 ENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKD 480

Query: 481 IMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGIT 540
           IMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGIT
Sbjct: 481 IMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGIT 540

Query: 541 YSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE 592
           YSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE
Sbjct: 541 YSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE 592


>gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens]
          Length = 594

 Score =  599 bits (1544), Expect = e-171
 Identities = 309/599 (51%), Positives = 442/599 (73%), Gaps = 22/599 (3%)

Query: 5   VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64
           +A  GLK+VV +KI   V    KK+GEWK++++D+ + ++L+SCCKMTD++ EGIT+VE+
Sbjct: 1   MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60

Query: 65  IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNK-IK 123
           I K REP+  ++A+Y ITP+ KSV   + DF      KY+AA+++FTD CPD LFN+ +K
Sbjct: 61  INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120

Query: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183
           +  +K I+   EINI+F+P+ESQVY+LD  D+F   YSP    A+ K+ I+E +A+QI T
Sbjct: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPH--KAQMKNPILERLAEQIAT 178

Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241
           +CATL E P VRY+ +  DNA  LAQL++ KL D YK D+ ++ +G  K  SQLLI+DRG
Sbjct: 179 LCATLKEYPAVRYRGEYKDNAL-LAQLIQDKL-DAYKADDPTMGEGPDKARSQLLILDRG 236

Query: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297
           FDP S VLHELTFQAM+YDLLPIEND YKY+T G    + KE +L+E+DDLW+ +RH+HI
Sbjct: 237 FDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHI 296

Query: 298 AVVLEEIPKLMKEISSTKKATEG-KTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMN 356
           A V +E+ + +K+ SS+K+   G KT++  L+Q++KKMP ++K+++K   HL+LAEDCM 
Sbjct: 297 AEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMK 356

Query: 357 KFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSIN 416
            ++  ++KLC+ EQDLA+GTDAEG+K+KD MR ++P+LL+ N    DKIR ILLYIF  N
Sbjct: 357 HYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKN 416

Query: 417 GTTEENLDRLIQNVKIENE-SDMIRNWSYLGVPIVPQS---QQGKPLRKDRSAEETFQLS 472
           G TEENL++LIQ+ +I  E S++I N ++LGVPIV  S   ++ KP RK+R +E+T+QLS
Sbjct: 417 GITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLS 476

Query: 473 RWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNG 528
           RWTP IKDIMED I+++LD+K +PY S   +    + AVSAR     K +A    + ++G
Sbjct: 477 RWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAP--GEYRSG 534

Query: 529 SKLIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVS 587
            +LI+F++GG++ +E+RCAYEV+QA+   EV+IGSTH+LTP+KLLD +K LNK  +++S
Sbjct: 535 PRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQKLLDTLKKLNKTDEEIS 593


>gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]
          Length = 603

 Score =  586 bits (1511), Expect = e-167
 Identities = 303/589 (51%), Positives = 433/589 (73%), Gaps = 22/589 (3%)

Query: 5   VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64
           +A  GLK+VV +KI   V    KK+GEWK++++D+ + ++L+SCCKMTD++ EGIT+VE+
Sbjct: 1   MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60

Query: 65  IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNK-IK 123
           I K REP+  ++A+Y ITP+ KSV   + DF      KY+AA+++FTD CPD LFN+ +K
Sbjct: 61  INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120

Query: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183
           +  +K I+   EINI+F+P+ESQVY+LD  D+F   YSP    A+ K+ I+E +A+QI T
Sbjct: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPH--KAQMKNPILERLAEQIAT 178

Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241
           +CATL E P VRY+ +  DNA  LAQL++ KL D YK D+ ++ +G  K  SQLLI+DRG
Sbjct: 179 LCATLKEYPAVRYRGEYKDNAL-LAQLIQDKL-DAYKADDPTMGEGPDKARSQLLILDRG 236

Query: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297
           FDP S VLHELTFQAM+YDLLPIEND YKY+T G    + KE +L+E+DDLW+ +RH+HI
Sbjct: 237 FDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHI 296

Query: 298 AVVLEEIPKLMKEISSTKKATEG-KTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMN 356
           A V +E+ + +K+ SS+K+   G KT++  L+Q++KKMP ++K+++K   HL+LAEDCM 
Sbjct: 297 AEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMK 356

Query: 357 KFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSIN 416
            ++  ++KLC+ EQDLA+GTDAEG+K+KD MR ++P+LL+ N    DKIR ILLYIF  N
Sbjct: 357 HYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKN 416

Query: 417 GTTEENLDRLIQNVKIENE-SDMIRNWSYLGVPIVPQS---QQGKPLRKDRSAEETFQLS 472
           G TEENL++LIQ+ +I  E S++I N ++LGVPIV  S   ++ KP RK+R +E+T+QLS
Sbjct: 417 GITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLS 476

Query: 473 RWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNG 528
           RWTP IKDIMED I+++LD+K +PY S   +    + AVSAR     K +A    + ++G
Sbjct: 477 RWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAP--GEYRSG 534

Query: 529 SKLIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIK 577
            +LI+F++GG++ +E+RCAYEV+QA+   EV+IGSTH+LTP K L D++
Sbjct: 535 PRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLR 583


>gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens]
          Length = 593

 Score =  529 bits (1362), Expect = e-150
 Identities = 277/598 (46%), Positives = 407/598 (68%), Gaps = 20/598 (3%)

Query: 5   VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64
           +A  GLK+VV +KI + V    KK+GEWK++++D  + ++L+SCCKM+D+L EGIT+VE+
Sbjct: 1   MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVED 60

Query: 65  IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKI-K 123
           I K REP+  ++A+Y ++PT KSV   + DF       YKAA+I+FTD CP+ LF+++ +
Sbjct: 61  INKRREPIPSLEAIYLLSPTEKSVQALIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGR 120

Query: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183
           +  +K ++  KEI+++F+P+E+QV++LD P + Y  Y P    A+ +   +E +A QI T
Sbjct: 121 SRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPF--RAEERTRQLEVLAQQIAT 178

Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241
           +CATL E P +RY+  P D A +LA  V  KL + +K D  SL +G  KT SQLLI+DR 
Sbjct: 179 LCATLQEYPAIRYRKGPEDTA-QLAHAVLAKL-NAFKADTPSLGEGPEKTRSQLLIMDRA 236

Query: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297
            DPVS +LHELTFQAMAYDLL IE DTY+Y+T G    +EK  +L+E+DDLWV +RH HI
Sbjct: 237 ADPVSPLLHELTFQAMAYDLLDIEQDTYRYETTGLSEAREKAVLLDEDDDLWVELRHMHI 296

Query: 298 AVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNK 357
           A V +++ +L++    +K+ T  K ++  L+Q++KKMP ++K++ K   HL+LA+DCM  
Sbjct: 297 ADVSKKVTELLRTFCESKRLTTDKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKH 356

Query: 358 FKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSING 417
           FK ++EKLC  EQDLA+G+DAEG+K+KDSM++++PVLL+      DKIR +LLYI   NG
Sbjct: 357 FKGSVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNG 416

Query: 418 TTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKD--RSAEETFQLSRWT 475
            +EENL +LIQ+  ++  S +IRN   LG  +      G   R +     E T+QLSRWT
Sbjct: 417 VSEENLAKLIQHANVQAHSSLIRNLEQLGGTVTNPGGSGTSSRLEPRERMEPTYQLSRWT 476

Query: 476 PFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNGSKL 531
           P IKD+MEDA+++RLD   WP+ S      +   AVSAR     K +A    + + G +L
Sbjct: 477 PVIKDVMEDAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGI--EARAGPRL 534

Query: 532 IVFVIGGITYSEVRCAYEVSQAHK-SCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSL 588
           IV+V+GG+  SE+R AYEV++A +   EV+IGS+H+LTP + LDD+K L+K  + ++L
Sbjct: 535 IVYVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALDKKLEDIAL 592


>gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens]
          Length = 590

 Score =  521 bits (1342), Expect = e-148
 Identities = 275/598 (45%), Positives = 407/598 (68%), Gaps = 23/598 (3%)

Query: 5   VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64
           +A  GLK+VV +KI + V    KK+GEWK++++D  + ++L+SCCKM+D+L EGIT+VE+
Sbjct: 1   MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVED 60

Query: 65  IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKI-K 123
           I K REP+  ++A+Y ++PT K++   + DF       YKAA+I+FTD CP+ LF+++ +
Sbjct: 61  INKRREPIPSLEAIYLLSPTEKAL---IKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGR 117

Query: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183
           +  +K ++  KEI+++F+P+E+QV++LD P + Y  Y P    A+ +   +E +A QI T
Sbjct: 118 SRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPF--RAEERTRQLEVLAQQIAT 175

Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241
           +CATL E P +RY+  P D A +LA  V  KL + +K D  SL +G  KT SQLLI+DR 
Sbjct: 176 LCATLQEYPAIRYRKGPEDTA-QLAHAVLAKL-NAFKADTPSLGEGPEKTRSQLLIMDRA 233

Query: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297
            DPVS +LHELTFQAMAYDLL IE DTY+Y+T G    +EK  +L+E+DDLWV +RH HI
Sbjct: 234 ADPVSPLLHELTFQAMAYDLLDIEQDTYRYETTGLSEAREKAVLLDEDDDLWVELRHMHI 293

Query: 298 AVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNK 357
           A V +++ +L++    +K+ T  K ++  L+Q++KKMP ++K++ K   HL+LA+DCM  
Sbjct: 294 ADVSKKVTELLRTFCESKRLTTDKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKH 353

Query: 358 FKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSING 417
           FK ++EKLC  EQDLA+G+DAEG+K+KDSM++++PVLL+      DKIR +LLYI   NG
Sbjct: 354 FKGSVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNG 413

Query: 418 TTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKD--RSAEETFQLSRWT 475
            +EENL +LIQ+  ++  S +IRN   LG  +      G   R +     E T+QLSRWT
Sbjct: 414 VSEENLAKLIQHANVQAHSSLIRNLEQLGGTVTNPGGSGTSSRLEPRERMEPTYQLSRWT 473

Query: 476 PFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNGSKL 531
           P IKD+MEDA+++RLD   WP+ S      +   AVSAR     K +A    + + G +L
Sbjct: 474 PVIKDVMEDAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGI--EARAGPRL 531

Query: 532 IVFVIGGITYSEVRCAYEVSQAHK-SCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSL 588
           IV+V+GG+  SE+R AYEV++A +   EV+IGS+H+LTP + LDD+K L+K  + ++L
Sbjct: 532 IVYVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALDKKLEDIAL 589


>gi|18105063 vacuolar protein sorting 45A [Homo sapiens]
          Length = 570

 Score =  118 bits (296), Expect = 1e-26
 Identities = 118/568 (20%), Positives = 253/568 (44%), Gaps = 67/568 (11%)

Query: 33  KIMLLDEFTTKLLASCCKMTDLLEEGITVVENI-YKNREPVRQMKALYFITPTSKSVDCF 91
           K++L+D+ TT +++     +++L++ + + E I  +NRE ++ +KA+ F+ PT ++VD  
Sbjct: 23  KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYI 82

Query: 92  LHDFASKSENKYKAAYIYFTD-FCPDNLFNKIKASCSKSIRRCKEINISFIPHESQVYTL 150
           + +       KY   +IYF++     ++ +  +A   + +   +E    +I     +++L
Sbjct: 83  IQELRRP---KYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSL 139

Query: 151 DVPDAFYYCYSPDPGNAKGKD---AIMETMADQIVTVCATLDENPGVRYKSKPLDNASKL 207
           ++            G  +G++   A +      +  +  +L + P +RY+    + A +L
Sbjct: 140 NIL-----------GCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSS-EAAKRL 187

Query: 208 AQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIEN- 266
           A+ V++ +   Y++ E    + +    LLI+DR  D ++ +L++ T+QAM ++LL I N 
Sbjct: 188 AECVKQVITKEYELFE--FRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNN 245

Query: 267 --DTYKYKTDGKE-KEAILE-EEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKT 322
             D  +     K+ +E +L  E D+ +    + + A +   I  LM++    K   + K 
Sbjct: 246 RIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKL 305

Query: 323 -SLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKF-KLNIEKLCKTEQDLALGTDAEG 380
            S++ +   ++  P F+K       H+ +  +      + N+ ++ + EQ+LA   D   
Sbjct: 306 ESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSS 365

Query: 381 QKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIENESDMIR 440
                +++ +  +L N      D  R ++LY       +  +L  L+ +++ +  S+  R
Sbjct: 366 -----ALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYR 420

Query: 441 NWSYLGVPIVPQSQQGKPLRKDRSAEETFQ------------LSRWTPFIKDIMEDAIDN 488
                 V    +  +G  L   + A    +             ++  PF+ + ++  I  
Sbjct: 421 KLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG 480

Query: 489 RLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRCAY 548
           RL    +PY           G  + R +P+            +IVFVIGG TY E    Y
Sbjct: 481 RLKENLYPYL----------GPSTLRDRPQ-----------DIIVFVIGGATYEEALTVY 519

Query: 549 EVSQAHKSCEVIIGSTHVLTPKKLLDDI 576
            +++      +++G T V   K  L+++
Sbjct: 520 NLNRTTPGVRIVLGGTTVHNTKSFLEEV 547


>gi|33469966 vesicle transport-related protein isoform a [Homo
           sapiens]
          Length = 642

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 88/425 (20%), Positives = 171/425 (40%), Gaps = 68/425 (16%)

Query: 29  EGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYKNREPVRQMKALYFITPTSKSV 88
           E  WK+++ D F   +++    + +L + GIT+   ++ +R+P+  + A+YF+ PT +++
Sbjct: 40  EPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENI 99

Query: 89  DCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKI-----KASCSKSIRRCKEINISFIPH 143
           D    D  ++    Y++ Y+ F      +    I      AS    + +  +  ++FI  
Sbjct: 100 DRMCQDLRNQ---LYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITL 156

Query: 144 ESQVYTLDVPDAFYYCY----SPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSK 199
           E  ++ L   +     Y     PD  + +  + +M+T+ D +     TL   P +R    
Sbjct: 157 EDDMFVLCNQNKELVSYRAINRPDITDTE-METVMDTIVDSLFCFFVTLGAVPIIRCSRG 215

Query: 200 PLDNASKLAQLVEKKLEDYYKIDEKSLIKGKT---------HSQLLIIDRGFDPVSTVLH 250
               A  +A  ++KKL +  +    SL  G T            L+++DR  D  + + H
Sbjct: 216 TA--AEMVAVKLDKKLRENLRDARNSLFTGDTLGAGQFSFQRPLLVLVDRNIDLATPLHH 273

Query: 251 ELTFQAMAYDLLP-------------IENDTYKYKTDGKEKEAI-LEEEDDLWVRIRHRH 296
             T+QA+ +D+L              +EN     +   K K++  L   D  W + +   
Sbjct: 274 TWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSP 333

Query: 297 IAVVLEEIP-------------KLMKEISSTKKATEGKTSL-----SALTQLMKKMPHFR 338
              V E +              K +K I   +   EG  S+     + LT  +  +P   
Sbjct: 334 FPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELL 393

Query: 339 KQITKQVVHLNLAEDCMNK---------FKLNIEKLCKTEQD---LALGTDAEGQKVKDS 386
           ++     +H N+A   +           F+   + + KT  D   L + +D +    +D 
Sbjct: 394 EKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDIISDPDAGTPEDK 453

Query: 387 MRVLL 391
           MR+ L
Sbjct: 454 MRLFL 458


>gi|33469978 vesicle transport-related protein isoform b [Homo
           sapiens]
          Length = 575

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 82/396 (20%), Positives = 156/396 (39%), Gaps = 68/396 (17%)

Query: 58  GITVVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDN 117
           GIT+   ++ +R+P+  + A+YF+ PT +++D    D  ++    Y++ Y+ F      +
Sbjct: 2   GITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQ---LYESYYLNFISAISRS 58

Query: 118 LFNKI-----KASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCY----SPDPGNAK 168
               I      AS    + +  +  ++FI  E  ++ L   +     Y     PD  + +
Sbjct: 59  KLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTE 118

Query: 169 GKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIK 228
             + +M+T+ D +     TL   P +R        A  +A  ++KKL +  +    SL  
Sbjct: 119 -METVMDTIVDSLFCFFVTLGAVPIIRCSRGTA--AEMVAVKLDKKLRENLRDARNSLFT 175

Query: 229 GKT---------HSQLLIIDRGFDPVSTVLHELTFQAMAYDLLP-------------IEN 266
           G T            L+++DR  D  + + H  T+QA+ +D+L              +EN
Sbjct: 176 GDTLGAGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVEN 235

Query: 267 DTYKYKTDGKEKEAI-LEEEDDLWVRIRHRHIAVVLEEIP-------------KLMKEIS 312
                +   K K++  L   D  W + +      V E +              K +K I 
Sbjct: 236 SPAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIM 295

Query: 313 STKKATEGKTSL-----SALTQLMKKMPHFRKQITKQVVHLNLAEDCMNK---------F 358
             +   EG  S+     + LT  +  +P   ++     +H N+A   +           F
Sbjct: 296 GLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYF 355

Query: 359 KLNIEKLCKTEQD---LALGTDAEGQKVKDSMRVLL 391
           +   + + KT  D   L + +D +    +D MR+ L
Sbjct: 356 EYEEKIMSKTTLDKSLLDIISDPDAGTPEDKMRLFL 391


>gi|18105056 vacuolar protein sorting 33A [Homo sapiens]
          Length = 596

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 104/598 (17%), Positives = 225/598 (37%), Gaps = 82/598 (13%)

Query: 33  KIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYKNREPVRQMK-ALYFITPTSKSVDCF 91
           K ++ DE+ T       + + L E  +  +  +  NR P   +K  ++F+ P  + +D  
Sbjct: 34  KAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGNRLPAADVKNIIFFVRPRLELMDII 93

Query: 92  LHDFASKSEN-KYKAAYIYFTD----FCPDNLFNKIKASCSKSIRRCKEINISFIPHESQ 146
             +  S+      +  +I F       C   L  K        I R +E ++  IP +  
Sbjct: 94  AENVLSEDRRGPTRDFHILFVPRRSLLCEQRL--KDLGVLGSFIHR-EEYSLDLIPFDGD 150

Query: 147 VYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASK 206
           + +++   AF  CY       +G    +   A  ++T+ A     P +  K +     + 
Sbjct: 151 LLSMESEGAFKECY------LEGDQTSLYHAAKGLMTLQALYGTIPQIFGKGECARQVAN 204

Query: 207 LAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAM--------- 257
           +  ++  K E  +   + S+        LL++DR  D ++ +  +LT++ +         
Sbjct: 205 M--MIRMKRE--FTGSQNSIFP--VFDNLLLLDRNVDLLTPLATQLTYEGLIDEIYGIQN 258

Query: 258 AYDLLPIENDTYKYKTDG------KEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEI 311
           +Y  LP E    K + DG      + K+  L   ++L+  IR ++   V   + K  K I
Sbjct: 259 SYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKII 318

Query: 312 SSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAE--DCMNKFKLNIEKLCKTE 369
           S+  +      ++  + Q + ++PH +        H ++AE    +   +   +KL   E
Sbjct: 319 SAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDVTTSEDFFDKL-TVE 377

Query: 370 QDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQN 429
           Q+   G D       D +   +   + + H     +R + L     +G  ++ LD     
Sbjct: 378 QEFMSGIDT------DKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGLKQKVLDYY--- 428

Query: 430 VKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNR 489
                + ++++ + Y  +  +   ++   L+        +   R T  ++  M+D  +  
Sbjct: 429 -----KREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKT--LRLWMDDVNEQN 481

Query: 490 LDSKEWPYCSQCPAV-----------WNG--------SGAVSARQKPRANYLEDRKNGSK 530
                + Y    P             W           G     ++P    L+ ++   +
Sbjct: 482 PTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPGE 541

Query: 531 ---LIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDK 585
               ++F +GG+T++E+     +SQ         G+ +V+   KL++    +    +K
Sbjct: 542 NRVTLIFFLGGVTFAEIAALRFLSQLEDG-----GTEYVIATTKLMNGTSWIEALMEK 594


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 53/246 (21%), Positives = 106/246 (43%), Gaps = 35/246 (14%)

Query: 201  LDNASKLAQLVEK---KLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAM 257
            LD+A   A   EK    ++D +    + L        LL+ +R  + +S   H       
Sbjct: 1150 LDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNH------- 1202

Query: 258  AYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKA 317
                  ++   Y+Y+ +  E+E +        VR   + +A  L++  + M E +S +  
Sbjct: 1203 ------LKERQYQYENEKAEREVV--------VRQLQQELADTLKK--QSMSE-ASLEVT 1245

Query: 318  TEGKTSLSALTQ-LMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGT 376
            +  + +L   TQ L KK+   R Q+ +       A  C  K + + +KL K    L +  
Sbjct: 1246 SRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTV 1305

Query: 377  DAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDR-LIQNVKIENE 435
              +  K+++  + LL    N + D  ++++ ++     +  + E NLD+ + +NV++E E
Sbjct: 1306 KKQMDKIEELQKNLLNA--NLSEDEKEQLKKLM----ELKQSLECNLDQEMKKNVELERE 1359

Query: 436  SDMIRN 441
                +N
Sbjct: 1360 ITGFKN 1365


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 32.7 bits (73), Expect = 0.96
 Identities = 66/301 (21%), Positives = 124/301 (41%), Gaps = 42/301 (13%)

Query: 274  DGKEKEAILEEEDDLWVRIRHRHIAVVLEEIP-KLMKEISSTKKATEGKTSLSALTQLMK 332
            + KEK +ILE+ED+    ++    A + E +P KL K I+S    T+G   +S+  Q  +
Sbjct: 2742 EAKEKLSILEKEDE--TEVQESKKACMFEPLPIKLSKSIAS---QTDGTLKISSSNQTPQ 2796

Query: 333  KMPHFRKQITKQVVHLNLAEDC--------MNKFKLNIEKLCKTEQDLALGTDAEGQKVK 384
             +      +    + +NL  +C        +++F   IEK+ +      L  ++      
Sbjct: 2797 IL------VKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISET 2850

Query: 385  DSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRL-IQNVKIENESDMIRNWS 443
            ++++    V +    + C  ++A++  + S  G++   L        +    SD   +W 
Sbjct: 2851 ETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTREICSSDSGSDW- 2909

Query: 444  YLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTP-FIKDIMEDAIDNR----LDSKEWPYC 498
              G  I     QG  +  +   EE+   +   P  IK ++  A+ N     L   E PY 
Sbjct: 2910 --GQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLR-AVHNEGMQVLSLTESPY- 2965

Query: 499  SQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRC---AYEVSQAHK 555
                      G   + Q+    +LE+RK     I  +   IT  +++     Y+ SQ+H+
Sbjct: 2966 --------SDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHE 3017

Query: 556  S 556
            S
Sbjct: 3018 S 3018


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 32.7 bits (73), Expect = 0.96
 Identities = 66/301 (21%), Positives = 124/301 (41%), Gaps = 42/301 (13%)

Query: 274  DGKEKEAILEEEDDLWVRIRHRHIAVVLEEIP-KLMKEISSTKKATEGKTSLSALTQLMK 332
            + KEK +ILE+ED+    ++    A + E +P KL K I+S    T+G   +S+  Q  +
Sbjct: 2734 EAKEKLSILEKEDE--TEVQESKKACMFEPLPIKLSKSIAS---QTDGTLKISSSNQTPQ 2788

Query: 333  KMPHFRKQITKQVVHLNLAEDC--------MNKFKLNIEKLCKTEQDLALGTDAEGQKVK 384
             +      +    + +NL  +C        +++F   IEK+ +      L  ++      
Sbjct: 2789 IL------VKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISET 2842

Query: 385  DSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRL-IQNVKIENESDMIRNWS 443
            ++++    V +    + C  ++A++  + S  G++   L        +    SD   +W 
Sbjct: 2843 ETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTREICSSDSGSDW- 2901

Query: 444  YLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTP-FIKDIMEDAIDNR----LDSKEWPYC 498
              G  I     QG  +  +   EE+   +   P  IK ++  A+ N     L   E PY 
Sbjct: 2902 --GQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLR-AVHNEGMQVLSLTESPY- 2957

Query: 499  SQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRC---AYEVSQAHK 555
                      G   + Q+    +LE+RK     I  +   IT  +++     Y+ SQ+H+
Sbjct: 2958 --------SDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHE 3009

Query: 556  S 556
            S
Sbjct: 3010 S 3010


>gi|31542785 sec1 family domain containing 2 [Homo sapiens]
          Length = 684

 Score = 32.7 bits (73), Expect = 0.96
 Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)

Query: 531 LIVFVIGGITYSEVRCAYE-VSQAHKSCEVIIGSTHVLTP 569
           LI+FV+GG+T SEV+   + V+      +VI+ ST +L P
Sbjct: 626 LILFVVGGVTVSEVKMVKDLVASLKPGTQVIVLSTRLLKP 665


>gi|122937249 glutamate receptor interacting protein 2 [Homo
           sapiens]
          Length = 1141

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 9/71 (12%)

Query: 411 YIFSINGTTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSA---EE 467
           +I SI+GT+ E+   L     + + S+ +R    L +  VPQSQ  +PLR  R     + 
Sbjct: 393 HILSIDGTSMEHCSLLEATKLLASISEKVR----LEILPVPQSQ--RPLRPQRQVVKVQR 446

Query: 468 TFQLSRWTPFI 478
           + QL RW P +
Sbjct: 447 SEQLHRWDPCV 457


>gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]
          Length = 1247

 Score = 31.6 bits (70), Expect = 2.1
 Identities = 33/138 (23%), Positives = 58/138 (42%), Gaps = 7/138 (5%)

Query: 360 LNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTT 419
           L I K    E++  +  D  GQK+   + +       K H    K   +   IF ++  +
Sbjct: 357 LMILKAILLEENNLIPVDQLGQKLLKKIGISWNKKYRKQHGPLRKFLQLHSQIFLLS--S 414

Query: 420 EENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIK 479
           +E+  RL++N  ++ ESD  RN   +   + P+S     L    S    F ++     ++
Sbjct: 415 DESTVRLLKNSSLQAESDFQRNDQQIFKMLPPES---PGLNNSISCPHWFDIN--DSKVQ 469

Query: 480 DIMEDAIDNRLDSKEWPY 497
            I E  I+ +   KE  Y
Sbjct: 470 PIREKDIEQQFQGKESAY 487


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 37/177 (20%), Positives = 81/177 (45%), Gaps = 18/177 (10%)

Query: 265  ENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKTSL 324
            END+ K K +  E+E  + EE+   V +   +    +E +   ++E++ + K  E     
Sbjct: 2148 ENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFE----- 2202

Query: 325  SALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQKVK 384
              L  L  +  +  KQI ++   L+  +  ++ FK  +E+  K + ++         ++K
Sbjct: 2203 LDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEE--KEQAEI---------QIK 2251

Query: 385  DSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNV-KIENESDMIR 440
            +  +  + +L N+  +  + + A L     I   TE++LD  I+   ++ N  + +R
Sbjct: 2252 EESKTAVEMLQNQLKELNEAV-AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLR 2307


>gi|45505178 cancer antigen 1 [Homo sapiens]
          Length = 641

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 71/394 (18%), Positives = 155/394 (39%), Gaps = 65/394 (16%)

Query: 201 LDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYD 260
           +D  +KL + VE+ +ED YKI                          +L +   +    +
Sbjct: 215 IDVINKLKENVEELIEDKYKI--------------------------ILEKNDTKKTLQN 248

Query: 261 LLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEG 320
           L  +  +T K+  + +  + +L+ +   + +I+  ++ +    + ++ ++  S  +  E 
Sbjct: 249 LEEVLANTQKHLQESRNDKEMLQLQ---FKKIKANYVCLQERYMTEMQQKNKSVSQYLEM 305

Query: 321 KTSLSALTQLMKKMPHFRKQITKQVVH-LNLAEDCMNKFKLNIEKLCKTEQDLALGTDAE 379
             +LS   + ++++   +K++ K     L+L +      +     L +  Q L      E
Sbjct: 306 DKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEE 365

Query: 380 GQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIENESDMI 439
            QK+K  +  LL  + N             L   S N  T        +N+K++ + + +
Sbjct: 366 RQKLKSRLEKLLTQVRN-------------LQFMSENERT--------KNIKLQQQINEV 404

Query: 440 RNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCS 499
           +N +      V +S++   + K  +A+   QL        DI +D       S   P CS
Sbjct: 405 KNENAKLKQQVARSEEQNYVPKFETAQLKDQLEE--VLKSDITKDT--KTTHSNLLPDCS 460

Query: 500 QCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEV--RCAYEVSQAHKSC 557
            C    N +         RA+ L  + +   L+  ++G +T  ++    A    ++ K  
Sbjct: 461 PCEERLNPADI------KRASQLASKMH--SLLALMVGLLTCQDIINSDAEHFKESEKVS 512

Query: 558 EVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKD 591
           ++++     L  KK   D ++++   D+   I+D
Sbjct: 513 DIMLQKLKSLHLKKKTLDKEVIDCDSDEAKSIRD 546



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 9/98 (9%)

Query: 299 VVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKF 358
           + L E+ + +K  +  ++    +   S L  L K++   + +ITKQ V +    D +NK 
Sbjct: 167 MALNEVLQKLKHTNRKQEVRIQELQCSNL-YLEKRVKELQMKITKQQVFI----DVINKL 221

Query: 359 KLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLN 396
           K N+E+L + +  + L    E    K +++ L  VL N
Sbjct: 222 KENVEELIEDKYKIIL----EKNDTKKTLQNLEEVLAN 255


>gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange
           protein 3 [Homo sapiens]
          Length = 2177

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 34/134 (25%), Positives = 64/134 (47%), Gaps = 20/134 (14%)

Query: 302 EEIPKLMKEISSTK------KATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCM 355
           E + KL KE S +K        T    +L  L  ++K  PH  ++  K ++ L LA +  
Sbjct: 3   EILRKLQKEASGSKYKAIKESCTWALETLGGLDTIVKIPPHVLRE--KCLLPLQLALESK 60

Query: 356 NKFKL------NIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAIL 409
           N  KL       ++KL   E+ +++ TD++ +++ + +   + V  + N D   ++  +L
Sbjct: 61  N-VKLAQHALAGMQKLLSEERFVSMETDSDEKQLLNQILNAVKVTPSLNEDLQVEVMKVL 119

Query: 410 LYI-----FSINGT 418
           L I     F +NG+
Sbjct: 120 LCITYTPTFDLNGS 133


>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
          Length = 1217

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 32/148 (21%), Positives = 60/148 (40%), Gaps = 34/148 (22%)

Query: 212 EKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIENDTYKY 271
           EK LE Y K+D+      +  +++  +DR +  V     EL  +             Y +
Sbjct: 428 EKNLEQYNKLDQDL---NEVKARVEELDRKYYEVKNKKDELQSER-----------NYLW 473

Query: 272 KTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLM 331
           + +  E++A+  + +DL             E+  +L++       A  GK  L+ +  + 
Sbjct: 474 REENAEQQALAAKREDL-------------EKKQQLLR-------AATGKAILNGIDSIN 513

Query: 332 KKMPHFRKQITKQVVHLNLAEDCMNKFK 359
           K + HFR++   Q V        MN F+
Sbjct: 514 KVLDHFRRKGINQHVQNGYHGIVMNNFE 541


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 37/202 (18%), Positives = 89/202 (44%), Gaps = 25/202 (12%)

Query: 189  DENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTV 248
            ++  G++++ K  +  +++ +L E+       I+ +   + KT  Q     R  + +S  
Sbjct: 1098 EQTLGLQFQKKIKELQARIEELEEE-------IEAERATRAKTEKQRSDYARELEELSER 1150

Query: 249  LHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLM 308
            L E          L  + +    K     +EA L+ E  +   +R +H     + + +L 
Sbjct: 1151 LEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEA-MVAALRKKHA----DSVAELG 1205

Query: 309  KEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKT 368
            ++I + ++  +         +L K+   F+ +I      L+ + + ++K K N+EK+C+T
Sbjct: 1206 EQIDNLQRVKQ---------KLEKEKSEFKLEIDD----LSSSMESVSKSKANLEKICRT 1252

Query: 369  EQDLALGTDAEGQKVKDSMRVL 390
             +D       + ++++ S+  L
Sbjct: 1253 LEDQLSEARGKNEEIQRSLSEL 1274


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 52/325 (16%), Positives = 134/325 (41%), Gaps = 44/325 (13%)

Query: 199  KPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMA 258
            K  D   K  Q ++KK     ++ E   +  K  +++  + + F+        L+ Q++ 
Sbjct: 1963 KSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEA-----QNLSMQSVR 2017

Query: 259  YDLLPIENDTYKYKTD----GKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISST 314
             D   +    ++   +     KE++ +   ++ L +  R + IA + E I +  +     
Sbjct: 2018 MDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKME-RDQFIATLREMIARDRQNHQVK 2076

Query: 315  KKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLAL 374
             +          LT+ +++     K++ K+   ++   +C+N+  L++EK  + +++L++
Sbjct: 2077 PEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSM 2136

Query: 375  GTDAEGQKVKDSMRVLLPVLLNKN---------------HDNCDKIRAILLYIFSINGTT 419
               A          + LP L  K+               H    K++ +L Y+  I    
Sbjct: 2137 RVKA---------NLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQ 2187

Query: 420  EENLDRLIQNV--KIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAE-------ETFQ 470
             E++++   +   ++E + +++    +L       S++ + L+ +++ +       + F 
Sbjct: 2188 HESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFS 2247

Query: 471  LSRWTPFIKDIMEDAIDNRLDSKEW 495
             S + P IK   +  + NR +  ++
Sbjct: 2248 ESEF-PSIKTEFQQVLSNRKEMTQF 2271


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 35/187 (18%), Positives = 76/187 (40%), Gaps = 27/187 (14%)

Query: 203  NASKLAQLVEKKLEDYYKIDEKSLIKG----KTHSQLLIIDRGFDPVSTVLHELTFQ--- 255
            N  K  + ++KK E+ Y + ++  IK     +T  Q +I+         +L + T +   
Sbjct: 868  NKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGE 927

Query: 256  ------AMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMK 309
                   +   +  +E +  K +    EK   +EE+ +          +   E   K  K
Sbjct: 928  LEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE----------SAAHEADLKRQK 977

Query: 310  EISSTKKATEGKTSLSA----LTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKL 365
             I  T  A + K  +      L+++ K++ H ++    + +HL+  +  +++ K  +EK 
Sbjct: 978  VIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKK 1037

Query: 366  CKTEQDL 372
                ++L
Sbjct: 1038 TNAVKEL 1044


>gi|171846278 leucine-rich repeat kinase 2 [Homo sapiens]
          Length = 2527

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 35/121 (28%), Positives = 60/121 (49%), Gaps = 19/121 (15%)

Query: 312 SSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLN---IEKLCKT 368
           SS+K+  +   S +AL+ L+++  +FRK +  + +HLN+ E  M K   +    E  CK 
Sbjct: 409 SSSKEVFQA--SANALSTLLEQNVNFRKILLSKGIHLNVLE-LMQKHIHSPEVAESGCKM 465

Query: 369 EQDLALGTDAEGQKVKDSMRVLLPVLLN--KNHD-----NCDKIRAILLYIFSINGTTEE 421
              L  G++       D M  ++P +L   K H+       + +RAIL +I  + G  EE
Sbjct: 466 LNHLFEGSNTS----LDIMAAVVPKILTVMKRHETSLPVQLEALRAILHFI--VPGMPEE 519

Query: 422 N 422
           +
Sbjct: 520 S 520


>gi|4506467 radixin [Homo sapiens]
          Length = 583

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 9/126 (7%)

Query: 264 IENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEI-SSTKKATEGKT 322
           +EN+  K +   KEKE I  E+++L  R++      + E+  K  KE+   T+KA E   
Sbjct: 323 LENEKKKREIAEKEKERIEREKEELMERLKQ-----IEEQTIKAQKELEEQTRKALELDQ 377

Query: 323 SLSALTQLMKKMPHFRK--QITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEG 380
                 +  +++   R+  +  K  +    A+   N+ +L  E L +    +AL  +A+ 
Sbjct: 378 ERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAE-LAEFTAKIALLEEAKK 436

Query: 381 QKVKDS 386
           +K +++
Sbjct: 437 KKEEEA 442


>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
          Length = 222

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 3/95 (3%)

Query: 166 NAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKS 225
           N  GKD   + + D  +   A L E   +   S+P +  +KLA + EK    Y+   EK 
Sbjct: 80  NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKV 139

Query: 226 LIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYD 260
           L   K+H Q  ++          L EL +     D
Sbjct: 140 L---KSHGQDYLVGNKLSRADIHLVELLYYVEELD 171


>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
          Length = 729

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 35/155 (22%), Positives = 63/155 (40%), Gaps = 41/155 (26%)

Query: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFD 243
           VC+++DEN G      P +  S+    +   + + YK+       G+T     I D  F 
Sbjct: 361 VCSSMDENDG------PGEEVSEEGFQIPATITERYKV-------GRT-----IGDGNFA 402

Query: 244 PVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEE 303
            V   +   T +  A  ++         K+  + KE +++ E  +  R++H +I +++EE
Sbjct: 403 VVKECVERSTAREYALKIIK--------KSKCRGKEHMIQNEVSILRRVKHPNIVLLIEE 454

Query: 304 IP---------------KLMKEISSTKKATEGKTS 323
           +                 L   I+ST K TE   S
Sbjct: 455 MDVPTELYLVMELVKGGDLFDAITSTNKYTERDAS 489


>gi|197209974 coiled-coil and C2 domain containing 2A isoform a [Homo
            sapiens]
          Length = 1620

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 17/74 (22%), Positives = 42/74 (56%), Gaps = 3/74 (4%)

Query: 212  EKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLP--IENDTY 269
            + +++  +KID   ++ G +  + +I++RGFD V + L E ++  +   + P  +  ++ 
Sbjct: 1196 QARIDGTFKIDIPPVLLGYSKERNMILERGFDSVRS-LSEGSYITLFITIEPQLVPGESI 1254

Query: 270  KYKTDGKEKEAILE 283
            + K + +E E +L+
Sbjct: 1255 REKFESQEDEKLLQ 1268


>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
          Length = 789

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 6/68 (8%)

Query: 451 PQSQQGKPLRKDRSAEETFQLSRWTPFIKDI-MEDAIDNRL-----DSKEWPYCSQCPAV 504
           P++++   LR+D   E  FQ+ R  P  ++I ++D I  RL     D    PY S     
Sbjct: 680 PEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRLKENDADPSAPPYDSLATYA 739

Query: 505 WNGSGAVS 512
           + G+ +++
Sbjct: 740 YEGNDSIA 747


>gi|157384973 tenascin R [Homo sapiens]
          Length = 1358

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 6/54 (11%)

Query: 244  PVSTVLHELTFQAMAYDLLP----IENDTYKYK-TDGKEKEAILEEEDDLWVRI 292
            P +    E+T Q+      P    IEN    YK TDG  KE I++ E D W+R+
Sbjct: 1044 PANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAE-DTWIRL 1096


>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
           [Homo sapiens]
          Length = 1005

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 28/135 (20%), Positives = 63/135 (46%), Gaps = 9/135 (6%)

Query: 261 LLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEE--IPKLMKEISSTKKAT 318
           L  +E D   Y+   ++ E +++E +DL +++       +  E  +     E++S K+  
Sbjct: 183 LTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQL 242

Query: 319 EGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFK---LNIEKLCKTEQDLALG 375
           E K   S + +L +K+    K    ++V  +  E+   K K   + ++K+ K  + L   
Sbjct: 243 EEKE--SEVKRLQEKLVCKMKGEGVEIVDRD--ENFKKKLKEKNIEVQKMKKAVESLMAA 298

Query: 376 TDAEGQKVKDSMRVL 390
            + + +K++D  + L
Sbjct: 299 NEEKDRKIEDLRQCL 313


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,720,700
Number of Sequences: 37866
Number of extensions: 929729
Number of successful extensions: 2513
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2450
Number of HSP's gapped (non-prelim): 43
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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