Guide to the Human Genome
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Search of human proteins with 118150660

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118150660 erythropoietin 4 immediate early response [Homo
sapiens]
         (426 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118150660 erythropoietin 4 immediate early response [Homo sap...   858   0.0  
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    48   1e-05
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    47   3e-05
gi|217416362 zinc finger CCCH-type containing 8 [Homo sapiens]         46   6e-05
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]         45   2e-04
gi|118766347 zinc finger CCCH-type domain containing 6 [Homo sap...    44   2e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       44   4e-04
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    42   8e-04
gi|55953127 RWD domain containing 1 isoform b [Homo sapiens]           42   8e-04
gi|55953125 RWD domain containing 1 isoform b [Homo sapiens]           42   8e-04
gi|55953123 RWD domain containing 1 isoform a [Homo sapiens]           42   8e-04
gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]       42   0.001
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            41   0.002
gi|148839339 nexilin (F actin binding protein) [Homo sapiens]          40   0.003
gi|5032243 makorin ring finger protein 3 [Homo sapiens]                40   0.005
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       40   0.005
gi|223468622 makorin ring finger protein 1 isoform 2 [Homo sapiens]    39   0.007
gi|223468620 makorin ring finger protein 1 isoform 1 [Homo sapiens]    39   0.007
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    39   0.009
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    39   0.009
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    39   0.009
gi|125987603 cleavage and polyadenylation specific factor 4, 30k...    38   0.020
gi|5729939 cleavage and polyadenylation specific factor 4, 30kDa...    38   0.020
gi|193788659 cleavage and polyadenylation specific factor 4-like...    37   0.026
gi|221219020 NYD-SP11 protein [Homo sapiens]                           37   0.045
gi|11067749 bromodomain containing protein 3 [Homo sapiens]            37   0.045
gi|30794372 polybromo 1 isoform 1 [Homo sapiens]                       37   0.045
gi|93102371 polybromo 1 isoform 2 [Homo sapiens]                       37   0.045
gi|41281917 polybromo 1 isoform 4 [Homo sapiens]                       37   0.045
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         37   0.045

>gi|118150660 erythropoietin 4 immediate early response [Homo
           sapiens]
          Length = 426

 Score =  858 bits (2216), Expect = 0.0
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 1   MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQV 60
           MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQV
Sbjct: 1   MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQV 60

Query: 61  AQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCK 120
           AQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCK
Sbjct: 61  AQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCK 120

Query: 121 FSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVC 180
           FSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVC
Sbjct: 121 FSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVC 180

Query: 181 KHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERER 240
           KHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERER
Sbjct: 181 KHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERER 240

Query: 241 SALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPE 300
           SALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPE
Sbjct: 241 SALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPE 300

Query: 301 LVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTS 360
           LVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTS
Sbjct: 301 LVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTS 360

Query: 361 DKDENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELN 420
           DKDENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELN
Sbjct: 361 DKDENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELN 420

Query: 421 TLDLEE 426
           TLDLEE
Sbjct: 421 TLDLEE 426


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 105/471 (22%), Positives = 188/471 (39%), Gaps = 110/471 (23%)

Query: 4   KKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNP------ 57
           K   +  GS++ E   K KI E        + G +  +F+++   Q K  +  P      
Sbjct: 156 KSNKKWDGSEEDEDNSK-KIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIES 214

Query: 58  -----------RQVAQSEAEKK----LKKDDKKKELQELNELFKPVVAAQKISKGADPKS 102
                      + VAQ +AEKK     K+D++K +L++L E        +++  G   +S
Sbjct: 215 GNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKE-------KEELETGKKDQS 267

Query: 103 VVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTM---DNWDEKKLE 159
                 KQ    K  + KF  + T++ K    +  I A +E+ E  T    DN  +KK +
Sbjct: 268 ------KQ----KESQRKFEEE-TVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKK 316

Query: 160 EVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKK 219
           +   KK  + EK+K K +   K  ++A++                     AL     LK+
Sbjct: 317 DKKKKKGEKEEKEKEKKKGPSKATVKAMQ--------------------EALAK---LKE 353

Query: 220 DKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKA 279
           +++++++E+E  ++ L E E         K   E  L  +KR+R     K +++ ER++ 
Sbjct: 354 EEERQKREEEERIKRLEELE--------AKRKEEERLEQEKRER-----KKQKEKERKER 400

Query: 280 DFKAGKALVISGRE----------VFEFRPELVNDDD---------EEADDTRYTQGTGG 320
             K GK L  S RE          + + +   V   D         E+    +  Q    
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460

Query: 321 DEVDDSVSV--------NDIDLSLYIPRDV---DETGITVASLERFSTYTSDKDENKLSE 369
            EV +S+ +          +      P  V   +E     A L+ +    SD++  K+ E
Sbjct: 461 KEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKV-E 519

Query: 370 ASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELN 420
            +    E  E  + EE+ E E  E+   +    +E    G + DE +E+++
Sbjct: 520 GNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVS 570



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 46/208 (22%), Positives = 86/208 (41%), Gaps = 20/208 (9%)

Query: 218 KKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERR 277
           +K+K ++  +D+I L+ L        G    K         KK+K ++K D  E D+ + 
Sbjct: 5   QKNKSEDSTKDDIDLDALAAEIE---GAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61

Query: 278 KADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLY 337
             +       + + RE    +P   N+++  + D +     G  +     S +D D    
Sbjct: 62  LEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQ-----SFDDNDSEEL 116

Query: 338 IPRDVDETGITVASLERFSTYTSDKDENKLSEASGGRAENGER----SDLEEDNEREGTE 393
             +D          +E +S    D D NKL + + G+A+   +    S+ +EDN ++  E
Sbjct: 117 EDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKE 176

Query: 394 NGAIDAVPVDENLFTGEDLDELEEELNT 421
              I++        +GE  DE +E L +
Sbjct: 177 RSRINS--------SGESGDESDEFLQS 196



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 89/404 (22%), Positives = 163/404 (40%), Gaps = 49/404 (12%)

Query: 32  KNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQE---LNELFKPV 88
           K++   K    + A+  +++       Q  Q    KK KK+ KK++  E   L EL +  
Sbjct: 8   KSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKK-KKEKKKQDFDEDDILKELEELS 66

Query: 89  VAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELE-K 147
           + AQ I    +  +V      + + T  DK K        +K +K+S + D   EELE K
Sbjct: 67  LEAQGIKADRETVAVKPTENNEEEFTSKDKKKKG------QKGKKQS-FDDNDSEELEDK 119

Query: 148 DTMDNWDEK-KLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICM 206
           D+      K K+E        +   K PK     K   +A ++NK    W   G  +   
Sbjct: 120 DSKSKKTAKPKVEMYSGSDDDDDFNKLPK-----KAKGKAQKSNKK---W--DGSEEDED 169

Query: 207 YRHALPPGFVLKKDKKKEEKEDEI--SLEDLIERERSALGPNVTKITLESFLAWK-KRKR 263
               +     +    +  ++ DE   S +   + +++  GPN+     +   ++K K   
Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVA 229

Query: 264 QEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEV 323
           Q+K +K E+  ER+K D +  K   +  +E  E   +   D  ++ +  R  +    + V
Sbjct: 230 QKKAEKKER--ERKKRDEEKAKLRKLKEKEELETGKK---DQSKQKESQRKFEE---ETV 281

Query: 324 DDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDL 383
              V+V              +TG+  AS E+  T T+ +D+N+  +    + +     + 
Sbjct: 282 KSKVTV--------------DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEE 327

Query: 384 EEDNEREGTENGAIDAV-PVDENLFTGEDLDELEEELNTLDLEE 426
           +E  +++G     + A+      L   E+  + EEE     LEE
Sbjct: 328 KEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEE 371



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 78/403 (19%), Positives = 156/403 (38%), Gaps = 61/403 (15%)

Query: 4   KKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQS 63
           K++ + G   +++QK+ ++  E++T         K +  +          +      A+ 
Sbjct: 256 KEELETGKKDQSKQKESQRKFEEET--------VKSKVTVDTGVIPASEEKAETPTAAED 307

Query: 64  EAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSH 123
           + E   KK DKKK+  E  E        +K  K    K+ V A  +     K ++ +   
Sbjct: 308 DNEGDKKKKDKKKKKGEKEE-------KEKEKKKGPSKATVKAMQEALAKLKEEEERQKR 360

Query: 124 DLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHF 183
           +   E +  KR   ++A+ +E E+   +  + KK +E   K     E+ K + +++ K  
Sbjct: 361 E---EEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERK-----ERLKKEGKLLTKSQ 412

Query: 184 LEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSAL 243
            EA    +     +   G ++   + +LP    + +DKK+++   ++  +++ E      
Sbjct: 413 REARARAEATLKLLQAQGVEVPS-KDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCA 471

Query: 244 GPNVTKITL----ESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVF---- 295
              V +  +    E+    +  + ++  D    D E   +D +  K   + G +V     
Sbjct: 472 AVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEK---VEGNKVHIEVK 528

Query: 296 ---------EFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETG 346
                    E   E   + +EE ++   ++G+ GDE D+ VS            D  ++G
Sbjct: 529 ENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVS------------DEKDSG 576

Query: 347 ITV-----ASLERFSTYTSDKDENKLSEASGGRAENGERSDLE 384
            T+       +   S Y SD D  K   A        E+  LE
Sbjct: 577 KTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLE 619


>gi|195976782 Paf1/RNA polymerase II complex component [Homo
           sapiens]
          Length = 710

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 38/148 (25%), Positives = 74/148 (50%), Gaps = 12/148 (8%)

Query: 217 LKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMER 276
           LK  KKKE+KE +   E+  E+E+  L   + +  + S    ++ KR EK+DK  Q ME 
Sbjct: 228 LKTAKKKEKKEKKKKQEE--EQEKKKL-TQIQESQVTSHNKERRSKRDEKLDKKSQAMEE 284

Query: 277 RKADFKAGK---ALVISGREVFEFRPELVNDDDEEADD------TRYTQGTGGDEVDDSV 327
            KA+ +  K   A +++ ++  +      +D++EE DD       R ++ +  DE ++  
Sbjct: 285 LKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKE 344

Query: 328 SVNDIDLSLYIPRDVDETGITVASLERF 355
            +      + +P +++   ++   LER+
Sbjct: 345 EIPPKSQPVSLPEELNRVRLSRHKLERW 372



 Score = 28.9 bits (63), Expect = 9.3
 Identities = 29/163 (17%), Positives = 70/163 (42%), Gaps = 6/163 (3%)

Query: 17  QKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKK 76
           ++  EK  E + F    K+   +++F      ++K   +  ++  + E +KK +++ +KK
Sbjct: 197 EQMTEKEREQELFNRIEKREVLKRRF------EIKKKLKTAKKKEKKEKKKKQEEEQEKK 250

Query: 77  ELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSV 136
           +L ++ E        ++ SK  +         ++ +  +  +   + +L  +++  K S 
Sbjct: 251 KLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSE 310

Query: 137 YIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIV 179
                +EE E D      ++      + +  E E+  PK+Q V
Sbjct: 311 VYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPV 353


>gi|217416362 zinc finger CCCH-type containing 8 [Homo sapiens]
          Length = 291

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 16/137 (11%)

Query: 3   PKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQ 62
           P++  +  G K   Q  K+K   +K     +K G KQ+K  +        G  N    A 
Sbjct: 109 PEESTKKEGVKDTPQAAKQK---NKNLKAGHKNG-KQKKMKRKWP-----GPGNKGSNAL 159

Query: 63  SEAEKKLKKDDKKKELQE-LNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKF 121
                  ++D K KE Q+ L++ F      ++  K       +C +F + +C KGD+CKF
Sbjct: 160 LRNSGSQEEDGKPKEKQQHLSQAFINQHTVERKGKQ------ICKYFLERKCIKGDQCKF 213

Query: 122 SHDLTLERKCEKRSVYI 138
            HD  +E+K E    Y+
Sbjct: 214 DHDAEIEKKKEMCKFYV 230



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 10/26 (38%), Positives = 17/26 (65%)

Query: 99  DPKSVVCAFFKQGQCTKGDKCKFSHD 124
           + K  +C F+ QG CT+G+ C + H+
Sbjct: 220 EKKKEMCKFYVQGYCTRGENCLYLHN 245



 Score = 28.9 bits (63), Expect = 9.3
 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 12/100 (12%)

Query: 34  KKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKK-----ELQELNELFKPV 88
           K   KQQ   +A  +Q    ++  +Q+ +   E+K  K D+ K     E+++  E+ K  
Sbjct: 171 KPKEKQQHLSQAFINQHTV-ERKGKQICKYFLERKCIKGDQCKFDHDAEIEKKKEMCKFY 229

Query: 89  VAAQKISKGAD----PKSVVCAFFKQG-QCTKGDKCKFSH 123
           V     ++G +         C F+  G +C +G+ CKFSH
Sbjct: 230 VQGY-CTRGENCLYLHNEYPCKFYHTGTKCYQGEYCKFSH 268


>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
          Length = 1303

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 18/36 (50%), Positives = 24/36 (66%)

Query: 103 VVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYI 138
           V+C +F +G+CT GD C FSHD+ L +K E    YI
Sbjct: 394 VICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYI 429



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 8/64 (12%)

Query: 111 GQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAE 170
           G C  GD C FSHD   E   E     + A D E   +     DEK++EE+  KK G   
Sbjct: 455 GNCINGDDCMFSHDPLTEETRELLDKML-ADDAEAGAE-----DEKEVEEL--KKQGINP 506

Query: 171 KKKP 174
             KP
Sbjct: 507 LPKP 510


>gi|118766347 zinc finger CCCH-type domain containing 6 [Homo
           sapiens]
          Length = 1189

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 19/137 (13%)

Query: 10  GGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKL 69
           G S   E  KK+++           KG +Q    +  +  V  G+  P+++ + E   + 
Sbjct: 186 GSSFSKESGKKQRM-----------KGVQQGIEQRVKSFNVGRGRGLPKKIKRKERGGRT 234

Query: 70  KKDDK----KKELQELNELFKP--VVAAQKISKGA--DPKSVVCAFFKQGQCTKGDKCKF 121
            K         + QE N+  K   V+  + I++         +C +F +G+C KGD+CKF
Sbjct: 235 NKGPNVFSVSDDFQEYNKPGKKWKVMTQEFINQHTVEHKGKQICKYFLEGRCIKGDQCKF 294

Query: 122 SHDLTLERKCEKRSVYI 138
            HD  LE++ E    Y+
Sbjct: 295 DHDAELEKRKEICKFYL 311



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 32/100 (32%)

Query: 99  DPKSVVCAFFKQGQCTK------------------------GDKCKFSHDLTLERKCEKR 134
           + +  +C F+ QG CTK                        GD CKFSHD  L ++ +K 
Sbjct: 301 EKRKEICKFYLQGYCTKGENCIYMHNEFPCKFYHSGAKCYQGDNCKFSHD-DLTKETKKL 359

Query: 135 SVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKP 174
              +   DEEL      N DE++LEE+  +K G     KP
Sbjct: 360 LDKVLNTDEEL-----INEDERELEEL--RKRGITPLPKP 392


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 59/297 (19%), Positives = 133/297 (44%), Gaps = 41/297 (13%)

Query: 1   MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQV 60
           M  +++  A   ++ ++++K    E +    + K+ A++++ IK    + +  ++  R  
Sbjct: 317 MREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKE--EEKRAAEERQRAR 374

Query: 61  AQSEAEKKLKKDDKKKELQELNELFKPV-VAAQKIS-----------KGADPKSVVCAFF 108
           A+ E + K+++  + K+L+E     +   +  +K+            K  + K       
Sbjct: 375 AEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLK 434

Query: 109 KQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGE 168
           KQG+  KG K +   +   E K   +   I  +DE+++KD      +++++  +++K G 
Sbjct: 435 KQGE-EKGTKVQAKREKLQEDKPTFKKEEI--KDEKIKKDKEP---KEEVKSFMDRKKGF 488

Query: 169 AEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHA-----LPPGFVLKKDKKK 223
            E K    + +  H L+  EN      +  PGG      + A     +  G  L++ +++
Sbjct: 489 TEVKSQNGEFMT-HKLKHTENT-----FSRPGGRASVDTKEAEGAPQVEAGKRLEELRRR 542

Query: 224 EEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKAD 280
             + +    E L ++++ A       + LE      K+KR+E+   LE++ +RRK +
Sbjct: 543 RGETESEEFEKLKQKQQEAA------LELEEL----KKKREERRKVLEEEEQRRKQE 589


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 74/328 (22%), Positives = 130/328 (39%), Gaps = 60/328 (18%)

Query: 4   KKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQV--KFGQQNPRQVA 61
           KK A+     ++E  K  K  +D     KN K   ++K +K  T     + G     +  
Sbjct: 289 KKNAKKSSDAESEDSKDAK--KDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKD 346

Query: 62  QSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKF 121
             + +KKLKKDDKKK+              +K  +  D +S             GD    
Sbjct: 347 TKKDKKKLKKDDKKKD-------------TKKYPESTDTES-------------GDAKDA 380

Query: 122 SHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCK 181
            +D    +K  K     D + ++ +K T     E +LE   ++K  + +KK  KT     
Sbjct: 381 RNDSRNLKKASKN----DDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTD---- 432

Query: 182 HFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERS 241
              ++++N++          GD              KK KK E+K  + S +D  ++++ 
Sbjct: 433 -NKKSVKNDEESTDADSEPKGD-------------SKKGKKDEKKGKKDSKKD--DKKKD 476

Query: 242 ALGPNVTKITLESFLAWKKRK---RQEKIDKLEQDMERRKADFKAGKALVISGREVFEFR 298
           A   N     +ES L  KK K   +++K  K +   + RK           S +  F+  
Sbjct: 477 A-KKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTS 535

Query: 299 PELVNDDDEEADDTRYTQGTGGDEVDDS 326
            + +   D E++++ Y  G    ++D+S
Sbjct: 536 TK-IKGSDTESEESLYKPG-AKKKIDES 561



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 45/196 (22%), Positives = 78/196 (39%), Gaps = 23/196 (11%)

Query: 2   PPKKQAQAGGSKKAEQKKKEKIIEDKT--------FGLKNKKGAKQQKFIKAVTHQVKFG 53
           P KK ++  G   A   + ++I+E+KT          LK+    +Q K  K+ + +    
Sbjct: 126 PLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKS-SSETNPE 184

Query: 54  QQNPRQVAQ--SEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCA----- 106
            QN + V++  S+ +KK  K+ KK   + L+    P    ++     DP S +C+     
Sbjct: 185 SQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLN 244

Query: 107 ---FFKQGQCTKGDKCKFSHDLTLERKCEKRSV-YIDARDEELEKDTMDNWDEKKLEEVV 162
                  GQ    D    + D  L    +  S  Y     +  +KDT  N  +    E  
Sbjct: 245 VDFLMLVGQ---SDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESE 301

Query: 163 NKKHGEAEKKKPKTQI 178
           + K  + + KK K  +
Sbjct: 302 DSKDAKKDSKKVKKNV 317


>gi|55953127 RWD domain containing 1 isoform b [Homo sapiens]
          Length = 147

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 20/120 (16%)

Query: 218 KKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERR 277
           +++KK++EKE E + + L            T +T+E+FL WK +   E    LE   +R 
Sbjct: 27  EEEKKQKEKEAEEAEKQLFHG---------TPVTIENFLNWKAKFDAE---LLEIKKKRM 74

Query: 278 KADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGD-EVDDSVSVNDIDLSL 336
           K + +AGK   +SG+++FE       D + +  D ++ +  G + EVD+S+     DL L
Sbjct: 75  KEEEQAGKN-KLSGKQLFE------TDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLEL 127


>gi|55953125 RWD domain containing 1 isoform b [Homo sapiens]
          Length = 147

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 20/120 (16%)

Query: 218 KKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERR 277
           +++KK++EKE E + + L            T +T+E+FL WK +   E    LE   +R 
Sbjct: 27  EEEKKQKEKEAEEAEKQLFHG---------TPVTIENFLNWKAKFDAE---LLEIKKKRM 74

Query: 278 KADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGD-EVDDSVSVNDIDLSL 336
           K + +AGK   +SG+++FE       D + +  D ++ +  G + EVD+S+     DL L
Sbjct: 75  KEEEQAGKN-KLSGKQLFE------TDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLEL 127


>gi|55953123 RWD domain containing 1 isoform a [Homo sapiens]
          Length = 243

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 20/120 (16%)

Query: 218 KKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERR 277
           +++KK++EKE E + + L            T +T+E+FL WK +   E    LE   +R 
Sbjct: 123 EEEKKQKEKEAEEAEKQLFHG---------TPVTIENFLNWKAKFDAE---LLEIKKKRM 170

Query: 278 KADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGD-EVDDSVSVNDIDLSL 336
           K + +AGK   +SG+++FE       D + +  D ++ +  G + EVD+S+     DL L
Sbjct: 171 KEEEQAGKN-KLSGKQLFE------TDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLEL 223


>gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]
          Length = 857

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 70/324 (21%), Positives = 120/324 (37%), Gaps = 70/324 (21%)

Query: 125 LTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFL 184
           L  +R  EK+S+Y    DEEL        D +K  ++V+      ++     ++   HF 
Sbjct: 107 LEQQRHHEKKSIYNLNEDEELTHYGQSLADIEKHNDIVDSDSDAEDRGTLSAELTAAHF- 165

Query: 185 EAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIE-RERSAL 243
                          GGG   +++     G   +K K ++E  +E+  +   E RER A 
Sbjct: 166 ---------------GGGGGLLHKKTQQEGEEREKPKSRKELIEELIAKSKQEKRERQAQ 210

Query: 244 GPNVTKITLESFLAWK--------KRKRQEKIDKLEQ------DMERRKADFKAGKALVI 289
             +  ++T +    WK        K  + E  DK E+      DM  R+  F+    +  
Sbjct: 211 REDALELTEKLDQDWKEIQTLLSHKTPKSENRDKKEKPKPDAYDMMVRELGFE----MKA 266

Query: 290 SGREVFEFRPELVNDDDE-----EADDTRYTQGTGGDE---VDDSVSVNDIDLSLYIPRD 341
                 +   EL  ++ E     EA+  R   G   DE       +S +D++    + +D
Sbjct: 267 QPSNRMKTEAELAKEEQEHLRKLEAERLRRMLGKDEDENVKKPKHMSADDLNDGFVLDKD 326

Query: 342 VDETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVP 401
                       R  +Y     + K++     + E  + +   E NE EG  +G      
Sbjct: 327 D----------RRLLSY----KDGKMNVEEDVQEEQSKEASDPESNEEEGDSSG------ 366

Query: 402 VDENLFTGEDLDELEEELNTLDLE 425
                  GED +E +   + LDLE
Sbjct: 367 -------GEDTEESDSPDSHLDLE 383


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 44/173 (25%), Positives = 81/173 (46%), Gaps = 27/173 (15%)

Query: 4   KKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQS 63
           KK+ +   +K+ E+K+K K  E K  G  +K+G ++++       + K  ++  R+  + 
Sbjct: 98  KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER-----KEERKREERKERERKKE 152

Query: 64  EAEK-KLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFS 122
           E EK + +K+ KK+E +++ E  K     +K  K            K+ +  K  K +  
Sbjct: 153 EREKERERKERKKRERKQVGE--KEEERKEKERKERK---------KRERNRKERKKERE 201

Query: 123 HDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPK 175
                ERK E++    + R +E +KD   NW E        K+ G+ E+K+ K
Sbjct: 202 RKERRERKKERKKK--EERKKERQKDRQTNWRE--------KERGKRERKERK 244



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 48/232 (20%), Positives = 91/232 (39%), Gaps = 57/232 (24%)

Query: 54  QQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQC 113
           ++  R++   +  KK ++ ++KKE +E  +  +     +K  +G   K            
Sbjct: 39  REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK------------ 86

Query: 114 TKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKK 173
            KG++ K       ERK  +R    +  ++E E+       EKK     +K+  E E+K+
Sbjct: 87  -KGERKKEER----ERKKRRR----EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137

Query: 174 PKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLE 233
            + +          E  K                          ++++KKEE+E E   +
Sbjct: 138 ERKR----------EERK--------------------------ERERKKEEREKERERK 161

Query: 234 DLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGK 285
           +  +RER  +G    +   +     KKR+R  K  K E++ + R+   K  K
Sbjct: 162 ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213


>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
          Length = 675

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 70/335 (20%), Positives = 130/335 (38%), Gaps = 64/335 (19%)

Query: 12  SKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKK 71
           S+KAE          KT+  K  KG  + KF      + +  Q+  R   Q   E+ +++
Sbjct: 5   SQKAEILLSSSKPVPKTYVPKLGKGDVKDKFEAMQRAREERNQRRSRDEKQRRKEQYIRE 64

Query: 72  DDKKKELQELNELFKP---VVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLE 128
            +  +  QE+ E+         + K+ K   PK            T   K +F+ ++  +
Sbjct: 65  REWNRRKQEIKEMLASDDEEDVSSKVEKAYVPK-----------LTGTVKGRFA-EMEKQ 112

Query: 129 RKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEK----------------- 171
           R+ E+R    + R   +E+D ++   ++K++  + K+  + E                  
Sbjct: 113 RQEEQRKRTEEERKRRIEQDMLE---KRKIQRELAKRAEQIEDINNTGTESASEEGDDSL 169

Query: 172 -------KKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKE 224
                  K  KT    K   E +E  +           +   Y       +  ++   KE
Sbjct: 170 LITVVPVKSYKTSGKMKKNFEDLEKEREE--------KERIKYEEDKRIRYEEQRPSLKE 221

Query: 225 EKEDEISLEDLIERE--RSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFK 282
            K   + ++D IE E  + +L P   K+T E      +R+RQE          +++A+ +
Sbjct: 222 AKCLSLVMDDEIESEAKKESLSPGKLKLTFEEL----ERQRQEN--------RKKQAEEE 269

Query: 283 AGKALVISGREVFEFRPELVNDDDEEADDTRYTQG 317
           A K L    R   E R ++VN+D+E  D  +  +G
Sbjct: 270 ARKRLEEEKRAFEEARRQMVNEDEENQDTAKIFKG 304



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 40/195 (20%), Positives = 91/195 (46%), Gaps = 13/195 (6%)

Query: 4   KKQAQAGGSKKAEQKKKEKIIEDK-TFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQ 62
           ++Q Q    K+AE++ ++++ E+K  F    ++   + +  +      K  +    +++ 
Sbjct: 255 ERQRQENRKKQAEEEARKRLEEEKRAFEEARRQMVNEDEENQDTAKIFKGYRPGKLKLSF 314

Query: 63  SEAEKKLKKDDKKKELQE----LNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDK 118
            E E++ ++D+K+K  +E    + E  K    A++     D    +     Q   T G K
Sbjct: 315 EEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPG-K 373

Query: 119 CKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQI 178
            + + +  L++K E+       R EE  K  ++   EK+  E + ++ GE E+++ +T  
Sbjct: 374 LEINFEELLKQKMEEEK----RRTEEERKHKLEM--EKQEFEQLRQEMGE-EEEENETFG 426

Query: 179 VCKHFLEAIENNKYG 193
           + + + E I+  + G
Sbjct: 427 LSREYEELIKLKRSG 441


>gi|5032243 makorin ring finger protein 3 [Homo sapiens]
          Length = 507

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 13/32 (40%), Positives = 22/32 (68%)

Query: 95  SKGADPKSVVCAFFKQGQCTKGDKCKFSHDLT 126
           S G   K ++C ++  GQC +G+ C++SHDL+
Sbjct: 91  SSGIWTKQIICRYYIHGQCKEGENCRYSHDLS 122


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 53/220 (24%), Positives = 84/220 (38%), Gaps = 25/220 (11%)

Query: 218  KKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERR 277
            +KDK+  + + +I  ED            +    LE     ++ +  EK D    D+++ 
Sbjct: 4708 EKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELE-----EQEEDDEKSDSEGGDLDKH 4762

Query: 278  KADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQ-----GTGGDEVDDSVSVNDI 332
              D        ++G E  +    L  DDDEE D+          G G DE D  +   D 
Sbjct: 4763 MGD--------LNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDD 4814

Query: 333  DLSLYIPRDVDETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGT 392
            +L                  E        + E+K++E    R  +    D    N+ +  
Sbjct: 4815 NLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVP 4874

Query: 393  ENGAIDAVPVDENLFT-----GEDLDELE-EELNTLDLEE 426
            E  A+D +P D NL +     GED D  E EE N L+++E
Sbjct: 4875 EPEALD-LPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKE 4913


>gi|223468622 makorin ring finger protein 1 isoform 2 [Homo sapiens]
          Length = 329

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 15/32 (46%), Positives = 20/32 (62%)

Query: 95  SKGADPKSVVCAFFKQGQCTKGDKCKFSHDLT 126
           S G   K V C +F  G C +GD C++SHDL+
Sbjct: 51  SGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLS 82



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 13/31 (41%), Positives = 22/31 (70%)

Query: 100 PKSVVCAFFKQGQCTKGDKCKFSHDLTLERK 130
           P SVVC +F++G C  GD+C++ H   L+++
Sbjct: 85  PYSVVCKYFQRGYCIYGDRCRYEHSKPLKQE 115


>gi|223468620 makorin ring finger protein 1 isoform 1 [Homo sapiens]
          Length = 482

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 15/32 (46%), Positives = 20/32 (62%)

Query: 95  SKGADPKSVVCAFFKQGQCTKGDKCKFSHDLT 126
           S G   K V C +F  G C +GD C++SHDL+
Sbjct: 51  SGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLS 82



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 13/31 (41%), Positives = 22/31 (70%)

Query: 100 PKSVVCAFFKQGQCTKGDKCKFSHDLTLERK 130
           P SVVC +F++G C  GD+C++ H   L+++
Sbjct: 85  PYSVVCKYFQRGYCIYGDRCRYEHSKPLKQE 115



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 6/49 (12%)

Query: 170 EKKKPKTQIVCKHFLEAIENNKYGWF----WVCPGGGDICMYRHALPPG 214
           E+K+ K +++ K + EA+ N    +F      CP GG+ C Y+HA P G
Sbjct: 349 EEKEEKQKLILK-YKEAMSNKACRYFDEGRGSCPFGGN-CFYKHAYPDG 395


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 62/288 (21%), Positives = 112/288 (38%), Gaps = 21/288 (7%)

Query: 141 RDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPG 200
           +DE+ ++       EK+ E    K+H E + K  +     K    A E+++        G
Sbjct: 101 KDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE-----RG 155

Query: 201 GGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKK 260
              +C++R  L      K++++++ +E +    +  ERER A      +       A  +
Sbjct: 156 NDGVCLFRDRLEQ-LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 214

Query: 261 RKRQEKIDKLEQDMERR------KADFKAGKALVISGREVFEFRPELVNDDDEEADDTRY 314
             R++  DK++     R      +  F+ G        E  E R +L++D  + +D  R 
Sbjct: 215 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER-DLLSDLQDISDSERK 273

Query: 315 TQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSDKDENKLS---EAS 371
           T        +      + +       + +E G T    E       +++E   S   EAS
Sbjct: 274 TSSAESSSAESGSGSEEEEEE---EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEAS 330

Query: 372 GGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEEL 419
              AE     ++ ED ERE  EN  +  VP         + +E EEE+
Sbjct: 331 EQSAEEVSEEEMSEDEERE-NENHLL-VVPESRFDRDSGESEEAEEEV 376



 Score = 32.7 bits (73), Expect = 0.64
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 5/63 (7%)

Query: 364 ENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELNTLD 423
           E K S A    AE+G  S+ EE+ E E  E G+      +E     E+ +E EEE    +
Sbjct: 271 ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE-----EEEEEEEEEETGSN 325

Query: 424 LEE 426
            EE
Sbjct: 326 SEE 328


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 55/281 (19%), Positives = 122/281 (43%), Gaps = 41/281 (14%)

Query: 13  KKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKD 72
           ++AEQ +++K+ EDK   L+  K  ++++  K +        Q   +V Q + EKK + +
Sbjct: 549 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL--------QARERVEQMKEEKKKQIE 600

Query: 73  DKKKELQELNELFKPV-VAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKC 131
            K  ++ E  E  K   +A +K  K A  K +     ++ Q  +  + ++   L  E + 
Sbjct: 601 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW---LQQEEEE 657

Query: 132 EKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNK 191
            +    +  + EE ++      + K+L E   ++  E E+++ + +   +   E  E  +
Sbjct: 658 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 717

Query: 192 YGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKIT 251
                                    L + +++ E+E   +  +L ERE++     + K  
Sbjct: 718 Q------------------------LAEQERRREQERLQAERELQEREKAL---RLQKEQ 750

Query: 252 LESFLAWKKRKRQEK--IDKLEQDMERRKADFKAGKALVIS 290
           L+  L  KK+K +++   ++  Q+ + +KA   AG +  ++
Sbjct: 751 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALN 791


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 55/281 (19%), Positives = 122/281 (43%), Gaps = 41/281 (14%)

Query: 13  KKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKD 72
           ++AEQ +++K+ EDK   L+  K  ++++  K +        Q   +V Q + EKK + +
Sbjct: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL--------QARERVEQMKEEKKKQIE 596

Query: 73  DKKKELQELNELFKPV-VAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKC 131
            K  ++ E  E  K   +A +K  K A  K +     ++ Q  +  + ++   L  E + 
Sbjct: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW---LQQEEEE 653

Query: 132 EKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNK 191
            +    +  + EE ++      + K+L E   ++  E E+++ + +   +   E  E  +
Sbjct: 654 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 713

Query: 192 YGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKIT 251
                                    L + +++ E+E   +  +L ERE++     + K  
Sbjct: 714 Q------------------------LAEQERRREQERLQAERELQEREKAL---RLQKEQ 746

Query: 252 LESFLAWKKRKRQEK--IDKLEQDMERRKADFKAGKALVIS 290
           L+  L  KK+K +++   ++  Q+ + +KA   AG +  ++
Sbjct: 747 LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALN 787


>gi|125987603 cleavage and polyadenylation specific factor 4, 30kDa
           isoform 2 [Homo sapiens]
          Length = 244

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 20/116 (17%)

Query: 101 KSVVCAFFKQGQCTKGDKCKFSH--DLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKL 158
           K+VVC  + +G C KGD+C+F H  D+T   +C   S + +  ++E     +D   E K+
Sbjct: 64  KTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHID--PESKI 121

Query: 159 EEVV-----NKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRH 209
           ++         KHG   + +   +++C ++L             CP G   C + H
Sbjct: 122 KDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGF----------CPEGPS-CKFMH 166


>gi|5729939 cleavage and polyadenylation specific factor 4, 30kDa
           isoform 1 [Homo sapiens]
          Length = 269

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 20/116 (17%)

Query: 101 KSVVCAFFKQGQCTKGDKCKFSH--DLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKL 158
           K+VVC  + +G C KGD+C+F H  D+T   +C   S + +  ++E     +D   E K+
Sbjct: 64  KTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHID--PESKI 121

Query: 159 EEVV-----NKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRH 209
           ++         KHG   + +   +++C ++L             CP G   C + H
Sbjct: 122 KDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGF----------CPEGPS-CKFMH 166


>gi|193788659 cleavage and polyadenylation specific factor 4-like
           [Homo sapiens]
          Length = 179

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 2/46 (4%)

Query: 101 KSVVCAFFKQGQCTKGDKCKFSH--DLTLERKCEKRSVYIDARDEE 144
           K VVC  + +G C KGD CKF H  DLT   +C   S + D  ++E
Sbjct: 64  KMVVCKHWLRGLCKKGDHCKFLHQYDLTRMPECYFYSKFGDCSNKE 109



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 13/23 (56%), Positives = 14/23 (60%)

Query: 102 SVVCAFFKQGQCTKGDKCKFSHD 124
           S VC FF +G C KG  C F HD
Sbjct: 38  SAVCNFFTKGLCEKGKLCPFRHD 60


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 51/239 (21%), Positives = 96/239 (40%), Gaps = 30/239 (12%)

Query: 13   KKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKD 72
            K++E  K EK +  K   L NK      K  K    + K  +++   +   E E  ++++
Sbjct: 2128 KRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEE 2187

Query: 73   DK----KKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCK---FSHDL 125
            +     K+  ++  E  +     +K S   D       F ++ +    +  K    S + 
Sbjct: 2188 EVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEE 2247

Query: 126  TLERKCEKRSVYIDARDEELEKDTMDNWDEKKLE-EVVNKKHGEAEKKKPKTQIVCKHFL 184
              ER+ E+     + R+EE E+   +  +EK++E E   KK  + EKKK + Q   + F 
Sbjct: 2248 EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE 2307

Query: 185  EAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSAL 243
            E                      +  +      +    +EE+E+  SLE+ ++RE+  L
Sbjct: 2308 E----------------------KEEIMSEEETESLSDEEEEEESCSLEEEVDREKEIL 2344



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 17/80 (21%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 216  VLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKID--KLEQD 273
            + KK+K  E ++  + +ED + +++  L     K+ LE  +   K++ + ++D  K E+ 
Sbjct: 1903 IKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKA 1962

Query: 274  MERRKADFKAGKALVISGRE 293
            +          K  ++ G+E
Sbjct: 1963 LNLEMKRLAEEKMRLVEGKE 1982


>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
          Length = 726

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 40/135 (29%), Positives = 61/135 (45%), Gaps = 11/135 (8%)

Query: 37  AKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISK 96
           A+ Q+ +KAV  Q+    Q P    + + EKK K + KKK+ ++  E  K     +K +K
Sbjct: 464 AELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEK-EKKKKDKEKEKEKHKVKAEEEKKAK 522

Query: 97  GADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDAR--DEELEKDTMDNWD 154
            A P        KQ Q  K    K +   T  R+ +K      A    EE E+    ++D
Sbjct: 523 VAPPA-------KQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYD 575

Query: 155 EKK-LEEVVNKKHGE 168
           EK+ L   +N+  GE
Sbjct: 576 EKRQLSLDINRLPGE 590


>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
          Length = 1602

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)

Query: 284  GKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVD 343
            GK +V+  +E F+  PE   D+D    ++RY+  T   +    +    I    ++PRDV 
Sbjct: 1001 GKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFK-KIKLWTMPISSVRFVPRDVP 1059

Query: 344  ETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTENG 395
               + VAS+  F+      DE     +   RAE+    + E+++      NG
Sbjct: 1060 LPVVRVASV--FANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNG 1109


>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
          Length = 1582

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)

Query: 284  GKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVD 343
            GK +V+  +E F+  PE   D+D    ++RY+  T   +    +    I    ++PRDV 
Sbjct: 1008 GKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFK-KIKLWTMPISSVRFVPRDVP 1066

Query: 344  ETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTENG 395
               + VAS+  F+      DE     +   RAE+    + E+++      NG
Sbjct: 1067 LPVVRVASV--FANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNG 1116


>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
          Length = 1582

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)

Query: 284  GKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVD 343
            GK +V+  +E F+  PE   D+D    ++RY+  T   +    +    I    ++PRDV 
Sbjct: 1033 GKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFK-KIKLWTMPISSVRFVPRDVP 1091

Query: 344  ETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTENG 395
               + VAS+  F+      DE     +   RAE+    + E+++      NG
Sbjct: 1092 LPVVRVASV--FANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNG 1141


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 32/110 (29%), Positives = 49/110 (44%), Gaps = 23/110 (20%)

Query: 2   PPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKA---------------- 45
           PP+   Q GG KK ++KK +K  +DK    K  K  K++K + A                
Sbjct: 798 PPRNSDQEGGGKKKKKKKDKKHKKDKKH--KKHKKHKKEKAVAAAAAAAVTPAAIAAATT 855

Query: 46  -VTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQE--LNELFKPVVAAQ 92
            +  +       P++  +SEAE  L  DD +K L+E  L  + K  V+ Q
Sbjct: 856 TLAQEEPVAAPEPKKETESEAEDNL--DDLEKHLREKALRSMRKAQVSPQ 903


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.131    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,524,829
Number of Sequences: 37866
Number of extensions: 864925
Number of successful extensions: 5140
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 4370
Number of HSP's gapped (non-prelim): 983
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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