Guide to the Human Genome
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Search of human proteins with 239751740

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751740 PREDICTED: hypothetical protein [Homo sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757232 PREDICTED: hypothetical protein [Homo sapiens]           949   0.0  
gi|239751740 PREDICTED: hypothetical protein [Homo sapiens]           949   0.0  
gi|239746241 PREDICTED: hypothetical protein XP_002343712 [Homo ...   945   0.0  
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       49   7e-06
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             47   5e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   5e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      45   1e-04
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    45   2e-04
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    45   2e-04
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          45   2e-04
gi|169169912 PREDICTED: hypothetical protein [Homo sapiens]            44   4e-04
gi|239749005 PREDICTED: hypothetical protein [Homo sapiens]            44   4e-04
gi|239743025 PREDICTED: hypothetical protein [Homo sapiens]            44   4e-04
gi|239757701 PREDICTED: hypothetical protein XP_002345525 [Homo ...    43   5e-04
gi|239752186 PREDICTED: hypothetical protein [Homo sapiens]            43   5e-04
gi|239746709 PREDICTED: hypothetical protein XP_002343816 [Homo ...    43   5e-04
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     42   0.001
gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]            42   0.001
gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]            42   0.001
gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]            42   0.001
gi|126352446 elastin isoform d precursor [Homo sapiens]                42   0.002
gi|126352322 elastin isoform c precursor [Homo sapiens]                41   0.002
gi|126352700 elastin isoform b precursor [Homo sapiens]                41   0.002
gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]            41   0.002
gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]            41   0.002
gi|38373671 SEC24-related protein C [Homo sapiens]                     41   0.002
gi|38373669 SEC24-related protein C [Homo sapiens]                     41   0.002
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      40   0.004
gi|169164783 PREDICTED: hypothetical protein [Homo sapiens]            40   0.004
gi|169163482 PREDICTED: hypothetical protein [Homo sapiens]            40   0.004

>gi|239757232 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 461

 Score =  949 bits (2454), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MGVGCSSCRLPCERTELCSRKRAGLLTGLGLRCDALRDSTCRSLRSECLLYGNRDFNQPW 60
           MGVGCSSCRLPCERTELCSRKRAGLLTGLGLRCDALRDSTCRSLRSECLLYGNRDFNQPW
Sbjct: 1   MGVGCSSCRLPCERTELCSRKRAGLLTGLGLRCDALRDSTCRSLRSECLLYGNRDFNQPW 60

Query: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGA 120
           PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGA
Sbjct: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGA 120

Query: 121 VGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGG 180
           VGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGG
Sbjct: 121 VGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGG 180

Query: 181 EKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP 240
           EKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP
Sbjct: 181 EKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP 240

Query: 241 SLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKT 300
           SLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKT
Sbjct: 241 SLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKT 300

Query: 301 PGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAA 360
           PGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAA
Sbjct: 301 PGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAA 360

Query: 361 VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG 420
           VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG
Sbjct: 361 VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG 420

Query: 421 LQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD 461
           LQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD
Sbjct: 421 LQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD 461


>gi|239751740 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 461

 Score =  949 bits (2454), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MGVGCSSCRLPCERTELCSRKRAGLLTGLGLRCDALRDSTCRSLRSECLLYGNRDFNQPW 60
           MGVGCSSCRLPCERTELCSRKRAGLLTGLGLRCDALRDSTCRSLRSECLLYGNRDFNQPW
Sbjct: 1   MGVGCSSCRLPCERTELCSRKRAGLLTGLGLRCDALRDSTCRSLRSECLLYGNRDFNQPW 60

Query: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGA 120
           PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGA
Sbjct: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGA 120

Query: 121 VGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGG 180
           VGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGG
Sbjct: 121 VGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGG 180

Query: 181 EKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP 240
           EKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP
Sbjct: 181 EKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP 240

Query: 241 SLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKT 300
           SLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKT
Sbjct: 241 SLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKT 300

Query: 301 PGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAA 360
           PGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAA
Sbjct: 301 PGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAA 360

Query: 361 VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG 420
           VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG
Sbjct: 361 VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG 420

Query: 421 LQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD 461
           LQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD
Sbjct: 421 LQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD 461


>gi|239746241 PREDICTED: hypothetical protein XP_002343712 [Homo
           sapiens]
          Length = 461

 Score =  945 bits (2443), Expect = 0.0
 Identities = 459/461 (99%), Positives = 459/461 (99%)

Query: 1   MGVGCSSCRLPCERTELCSRKRAGLLTGLGLRCDALRDSTCRSLRSECLLYGNRDFNQPW 60
           MGVGCSSCRLPCERTELCSRKRAGLLTGLGL CDALRDSTCRSL SECLLYGNRDFNQPW
Sbjct: 1   MGVGCSSCRLPCERTELCSRKRAGLLTGLGLTCDALRDSTCRSLHSECLLYGNRDFNQPW 60

Query: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGA 120
           PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGA
Sbjct: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGA 120

Query: 121 VGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGG 180
           VGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGG
Sbjct: 121 VGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGG 180

Query: 181 EKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP 240
           EKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP
Sbjct: 181 EKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP 240

Query: 241 SLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKT 300
           SLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKT
Sbjct: 241 SLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKT 300

Query: 301 PGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAA 360
           PGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAA
Sbjct: 301 PGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAA 360

Query: 361 VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG 420
           VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG
Sbjct: 361 VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG 420

Query: 421 LQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD 461
           LQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD
Sbjct: 421 LQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD 461


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 113/446 (25%), Positives = 158/446 (35%), Gaps = 64/446 (14%)

Query: 61  PPSPGRR-LNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGP--P 117
           P  PG   L+RP + +  G    SGL  ++G + G  G       + L       GP  P
Sbjct: 179 PSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGP 238

Query: 118 RGAVGAAGAQDFLNPR-----PLWPNLD-LPGL--RPGKITASARPSSQALQFANSRVSL 169
            G  G  G    +  R     P  P  D  PG    PG++  +  P ++    A     L
Sbjct: 239 PGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL 298

Query: 170 GTHRIGEGVGGEKRQEAGSPGWNPGLG-LARLGSYSTV----------CLAPELAFGLGG 218
             HR  +G+ G K  E G+PG     G    +G+   +           L P+ A G  G
Sbjct: 299 KGHRGHKGLEGPK-GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRG 357

Query: 219 VLRVSGPATPELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRG 278
              + G   P   L      P S G  G+ G   E G     GP  + P  +       G
Sbjct: 358 AHGMPGKPGPMGPLG----IPGSSGFPGNPGMKGEAGPTGARGP--EGPQGQRGETGPPG 411

Query: 279 AAASPCLQVAQQSFLELGAQKTPGG-GKNLGPRLCG----KSPRGSQTARSSS------- 326
              SP L  A      +G   TPG  G    P   G      P GS   + S+       
Sbjct: 412 PVGSPGLPGA------IGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRG 465

Query: 327 -PSRAWAPGWRQLGRGPATPMLHGL-GPVPPPLWAAVSASRWGGGGPQPLPQVSKEGS-- 382
            P     PG++        P  HG+ GP+ PP        R   G   P   V + G+  
Sbjct: 466 QPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG 525

Query: 383 --------GLARPDPSCCVRAGLGAAKTPGAQGE--RLGPRGTRRARGLQLRPVGGQSRR 432
                   GL  P  +   R  +G++   G+QG+  R G  G   ARGL   P       
Sbjct: 526 NRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEG 585

Query: 433 EAAPACSGPQPCRPHGTGAASSLGLQ 458
           +  P  +  +  RP   G   S+G++
Sbjct: 586 KLGPLGAPGEDGRP---GPPGSIGIR 608



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 133/477 (27%), Positives = 155/477 (32%), Gaps = 123/477 (25%)

Query: 58   QPWPPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGP- 116
            +P PP       +P ++  PGP  SSG   K G  AG  GV      R        +GP 
Sbjct: 598  RPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGE-AGNAGV---PGQRGAPGKDGEVGPS 653

Query: 117  -PRGAVGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVS-LGTH-- 172
             P G  G AG +    P        LPG  PG      +P  Q +      V  LG    
Sbjct: 654  GPVGPPGLAGERGEQGPPGPTGFQGLPG-PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGE 712

Query: 173  --RIGE-------GVGGEKRQEA--------GSPGWN--------PGL------------ 195
                GE       G+ GEK            GSPG +        PGL            
Sbjct: 713  RGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGT 772

Query: 196  --------GLARLGSYSTVCLAPELAFGLGGVLRVSGPATP-----ELALRSRAVTPPSL 242
                    G+   G+  T     + A GL G L   GPA P     E   R     P S 
Sbjct: 773  PGPKGDRGGIGEKGAEGTA--GNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSR 830

Query: 243  GGGGDRGENREEGRDLCLGPVAKKPDPRALA----ISSRGAAASPCLQVAQQSFLELGAQ 298
            G  G RGEN   G     GP      P           +G A SP  Q         G  
Sbjct: 831  GNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQ---------GLA 881

Query: 299  KTPG-GGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPL 357
             +PG  G N  P L  K  RG+Q      P     PG    GR         +GP  P  
Sbjct: 882  GSPGPHGPNGVPGL--KGGRGTQ----GPPGATGFPG--SAGR---------VGPPGPA- 923

Query: 358  WAAVSASRWGGGGPQ-PLPQVSKEGSGLARPDPSCCVRAG-LGAAKTPGAQGER------ 409
                     G  GP  PL +  KEG    R DP    R G  G A  PG  G++      
Sbjct: 924  ---------GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGED 974

Query: 410  --------LGPRGTRRARGLQLRPVGGQSRREAAPACSGP--QPCRPHGTGAASSLG 456
                     GP GT   RG+   P  GQ      P   GP   P +   TGA    G
Sbjct: 975  GQPGPDGPPGPAGTTGQRGIVGMP--GQRGERGMPGLPGPAGTPGKVGPTGATGDKG 1029


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 63/249 (25%), Positives = 89/249 (35%), Gaps = 25/249 (10%)

Query: 218 GVLRVSGPATPELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSR 277
           G  R SG  +P  +  S   +P   GG G R      GR         KP   +  +  +
Sbjct: 290 GSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS-GAHGGRPGSAHSPPDKPSSPSPRVRDK 348

Query: 278 GAAASPCLQVAQQSFLELGAQKTPGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQ 337
            AAA+P      +   E  + ++    +  G R  G + R  +  R    SR+ A   R+
Sbjct: 349 AAAAAPTPPARGK---ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRR 405

Query: 338 LGRGPATPMLHGLGPVPPPLWAAVSASRW--------GGGGPQPLPQVSKE----GSGLA 385
            GR    P         PP  ++ S SR         G G P P P+   E    G G  
Sbjct: 406 RGRRRPRPA--------PPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKR 457

Query: 386 RPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLRPVGGQSRREAAPACSGPQPCR 445
             +     R     + +PGA G R GP G   +R     P    S R  + + S     R
Sbjct: 458 AKERPPRARPA-STSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKR 516

Query: 446 PHGTGAASS 454
           PH    + S
Sbjct: 517 PHSPSRSPS 525


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 65/234 (27%), Positives = 86/234 (36%), Gaps = 31/234 (13%)

Query: 224  GPATP--ELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAA 281
            GPATP  + A    A TPPSL GG     ++       + P + K  P       +GA  
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP--PKGAPT 1311

Query: 282  SPCLQVAQQSFLELGAQKTPGG-GKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGR 340
             P            G+  TP   G    P +   SP+G+ T  +++PS            
Sbjct: 1312 PPAATPPSPK----GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK---------G 1358

Query: 341  GPATPMLHGLGPVPPPLWAAVSASRWGGGGPQPLPQVSKEGSGLARP--DPSCCVRAGLG 398
            GP TP     GP PP   AA  + +   GGP   P   K G  +  P  DP+      L 
Sbjct: 1359 GPTTPSSKE-GPTPP---AATPSHK---GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411

Query: 399  AAKTPGAQGERLGPRGTRRARGLQLRPVGGQSRREAAPACSGPQ--PCRPHGTG 450
              K P     R G      ++G    P       + APA S P+  P  P   G
Sbjct: 1412 PKKAPATPVTREG--AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 112/432 (25%), Positives = 132/432 (30%), Gaps = 72/432 (16%)

Query: 58  QPWPPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPP 117
           +P PP P     +P  +  PGP  + G   K G   G  G              P+ GPP
Sbjct: 562 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG------------PGPQ-GPP 608

Query: 118 RGAVGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEG 177
            G  G  G Q    P P  P  D     P        P  Q LQ        G      G
Sbjct: 609 -GKNGETGPQG--PPGPTGPGGDKGDTGP--------PGPQGLQ---GLPGTGGPPGENG 654

Query: 178 VGGE--KRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSR 235
             GE   + +AG+PG   G G A           P    G  G+   +GP  PE   +  
Sbjct: 655 KPGEPGPKGDAGAPGAPGGKGDAGAPGER----GPPGLAGAPGLRGGAGPPGPE-GGKGA 709

Query: 236 AVTPPSLGGGGDRGENREEGRDLCLGPVAKKPD------PRALAISSRGAAASPCLQVAQ 289
           A  P   G  G  G     G    LG    K D      P A  +  +     P   +  
Sbjct: 710 AGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGP 769

Query: 290 QSFLELGAQKTPGGGKNLGPRLCGKSPRGS--------------------QTARSSSPSR 329
                    K  GG   L P + G  PRGS                    Q         
Sbjct: 770 PGPAGQPGDKGEGGAPGL-PGIAG--PRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGE 826

Query: 330 AWAPGWRQLGRGPATP-MLHGLGPVPPPLWAAVSASRWGGGGPQPLPQVSKEGSGLARPD 388
             APG +  G  P       G GP  PP    V   R   GGP           GL  P 
Sbjct: 827 RGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAG--FPGARGLPGPP 884

Query: 389 PSCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQ--LRPVG--GQSRREAAPACSGPQPC 444
            S       G + +PG  G   GP G   A G      P G  GQ   + +P   GP P 
Sbjct: 885 GSNGNPGPPGPSGSPGKDGPP-GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGP-PG 942

Query: 445 RPHGTGAASSLG 456
            P   G A   G
Sbjct: 943 APGPLGIAGITG 954



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 103/418 (24%), Positives = 130/418 (31%), Gaps = 118/418 (28%)

Query: 59   PWPPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPR 118
            P PP P      P     PGP+ ++G     G V+G KG       +     +P    P 
Sbjct: 890  PGPPGPS---GSPGKDGPPGPAGNTGAPGSPG-VSGPKGDA----GQPGEKGSPGAQGPP 941

Query: 119  GAVGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGV 178
            GA G  G       R L     +PG R         P  Q ++  + +          G+
Sbjct: 942  GAPGPLGIAGITGARGLAGPPGMPGPR-------GSPGPQGVKGESGKPG------ANGL 988

Query: 179  GGEKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVT 238
             GE+    G PG   GL              P LA   G   R   P +  L  R     
Sbjct: 989  SGER----GPPG-PQGL--------------PGLAGTAGEPGRDGNPGSDGLPGRDG--- 1026

Query: 239  PPSLGGGGDRGENREEGRDLC---------LGPVAKKPDPRALAISSRGAAASPCLQVAQ 289
              S GG GDRGEN   G             +GP  K  D      +    A  P      
Sbjct: 1027 --SPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPA----- 1079

Query: 290  QSFLELGAQKTPGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHG 349
                  G++  PG           + PRG +   +     A   G R     P  P    
Sbjct: 1080 ------GSRGAPG----------PQGPRGDK-GETGERGAAGIKGHRGFPGNPGAP---- 1118

Query: 350  LGPVPPPLWAAVSASRWGGGGPQPLPQVSKEGS-GLARPDPSCCVRAGLGAAKTPGAQGE 408
                               G P P  Q    GS G A P      R  +G +  PG  G 
Sbjct: 1119 -------------------GSPGPAGQQGAIGSPGPAGP------RGPVGPSGPPGKDGT 1153

Query: 409  R--------LGPRGTRRARGLQLRPVGGQSRREAAPACSG-PQPCRPHGTGAASSLGL 457
                      GPRG R  RG +  P  G   +   P   G P PC   G GAA+  G+
Sbjct: 1154 SGHPGPIGPPGPRGNRGERGSEGSP--GHPGQPGPPGPPGAPGPC-CGGVGAAAIAGI 1208



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 61/235 (25%), Positives = 77/235 (32%), Gaps = 31/235 (13%)

Query: 236 AVTPPSLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLEL 295
           A +P S G  G RGE   +G     GP    P P  +  S  G        +     L +
Sbjct: 356 AGSPGSNGAPGQRGEPGPQGHAGAQGP----PGPPGINGSPGGKGEMGPAGIPGAPGL-M 410

Query: 296 GAQKTPG-GGKNLGPRLCG-------------KSPRGSQTARSSSPSRAWAPGWRQLGRG 341
           GA+  PG  G N  P L G               PRG +   +  P    A G       
Sbjct: 411 GARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRG-ERGEAGIPGVPGAKGEDGKDGS 469

Query: 342 PATPMLHGLGPVPPPLWAAVSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAK 401
           P  P  +GL   P       +    G  GP  +P           P P+       GAA 
Sbjct: 470 PGEPGANGL---PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPA----GPRGAAG 522

Query: 402 TPGAQGERLGPRGTRRARGLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLG 456
            PG  G   GP      RG+   P G  S  +  P  S  +  RP   G +   G
Sbjct: 523 EPGRDGVPGGP----GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRG 573


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 122/463 (26%), Positives = 150/463 (32%), Gaps = 95/463 (20%)

Query: 58   QPWPPSPGRRLNRPAAVREPGPSPSSGLAEKLG--AVAGKKGVFLLIFARLLTFAAPRLG 115
            +P PP P     +P  +  PGP  ++G   K G   + G  G+  L      T AA   G
Sbjct: 586  RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645

Query: 116  P-----PRGAVGAAGAQDFLN-PRPLWPNLDLPGLRPGKITASARPSSQAL-------QF 162
            P      RG  GA G   F   P P  P     G +PG         +  L        F
Sbjct: 646  PAGPAGERGEQGAPGPSGFQGLPGP--PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703

Query: 163  ANSRVSLGTHRI--------GEGVGGEKRQE--AGSPGWNPGLGLARL-GSYSTVCLA-- 209
               R S G   +          G  G K     AG PG     GL  + G      +A  
Sbjct: 704  PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 763

Query: 210  -----------PELAFGLGGVLRVSGPATPELALRSRA----VTPPS-LGGGGDRGENRE 253
                       PE A G  G   ++GP  P     +      V PP   G  G RG   E
Sbjct: 764  KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 823

Query: 254  EGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPGGGKNLGPRLCG 313
             G     GP    P P   A    GA   P  +  Q    + G    PG           
Sbjct: 824  RGE---TGP----PGPAGFA-GPPGADGQPGAKGEQGEAGQKGDAGAPG----------- 864

Query: 314  KSPRGSQTARS-SSPSRAWAPGWRQLGRGP--ATPMLHGLGPVPPPLWAAVSASRWGGGG 370
              P+G   A     P+    P   +  +GP  AT      G V PP       S    G 
Sbjct: 865  --PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP------GSNGNPGP 916

Query: 371  PQPLPQVSKEGSGLARPDPSCCVRAG----LGAAKTPGAQGE-----------RLGPRGT 415
            P P     K+G   AR D     RAG     G A  PG +GE             GP+G 
Sbjct: 917  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976

Query: 416  RRARGLQLRPVGGQSRREAAPACSGP--QPCRPHGTGAASSLG 456
               RG+   P  GQ      P   GP  +P +    GA+   G
Sbjct: 977  AGQRGIVGLP--GQRGERGFPGLPGPSGEPGKQGAPGASGDRG 1017



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 118/457 (25%), Positives = 154/457 (33%), Gaps = 85/457 (18%)

Query: 59  PWPPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPR 118
           P PP P       AA    G    +G A+ LG + G  G              PR GPP 
Sbjct: 167 PGPPGPPGLGGNFAAQMAGGFDEKAGGAQ-LGVMQGPMGPM-----------GPR-GPP- 212

Query: 119 GAVGAAGAQDF---------------LNPR-----PLWPNLDLPGLRPGKITASARPSSQ 158
           G  GA G Q F               + PR     P  P  D    +PGK      P  Q
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272

Query: 159 ALQ-FANSRVSLGT--HRIGEGVGGEKRQ--------EAGSPGWN--PGLGLARLGSYST 205
             + F  +    G   HR   G+ G K +        E+GSPG N  PG    R      
Sbjct: 273 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 332

Query: 206 VCLAPELAFGLGGVLRVSGPATPELAL--------------RSRAVTPPSLGGGGDRGEN 251
               P  A G  G     GPA P   +              +  A    + G  G +G  
Sbjct: 333 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 392

Query: 252 REEGRDLCLGPVAKKPDPRALAI-SSRGAAASPCLQVAQQSFLELGAQKTPGGGKNLGPR 310
            E G     GP     +P    I  ++G+A +P +  A       G     G    LGP+
Sbjct: 393 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 452

Query: 311 LCGKSP-----RGSQTARS----SSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAV 361
                P     +G Q  +     + P  A  P   +  RG A     G+GP+ PP     
Sbjct: 453 GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG-ARGEPGGVGPIGPP----- 506

Query: 362 SASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGE--RLGPRGTRRAR 419
                G  G +  P       GLA P  +   R   G A   GA G+  R G  G   AR
Sbjct: 507 --GERGAPGNRGFPGQD----GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560

Query: 420 GLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLG 456
           GL  RP     + +  P+ +  +  RP   G   + G
Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG 597



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 53/207 (25%), Positives = 66/207 (31%), Gaps = 34/207 (16%)

Query: 243  GGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPG 302
            G  G  G   E G     GP  +K +P     S       P     Q+  + L  Q+   
Sbjct: 933  GDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGER 992

Query: 303  GGKNL-GPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAV 361
            G   L GP              S  P +  APG     RGP        GPV PP     
Sbjct: 993  GFPGLPGP--------------SGEPGKQGAPG-ASGDRGPP-------GPVGPPGLTGP 1030

Query: 362  SASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGER-----LGPRGTR 416
            +      G P       ++G+   + D     R   GA   PGA G        GP G +
Sbjct: 1031 AGEPGREGSPGADGPPGRDGAAGVKGD-----RGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085

Query: 417  RARG-LQLRPVGGQSRREAAPACSGPQ 442
              RG    +   G S    A    GPQ
Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGIQGPQ 1112


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 122/463 (26%), Positives = 150/463 (32%), Gaps = 95/463 (20%)

Query: 58  QPWPPSPGRRLNRPAAVREPGPSPSSGLAEKLG--AVAGKKGVFLLIFARLLTFAAPRLG 115
           +P PP P     +P  +  PGP  ++G   K G   + G  G+  L      T AA   G
Sbjct: 517 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576

Query: 116 P-----PRGAVGAAGAQDFLN-PRPLWPNLDLPGLRPGKITASARPSSQAL-------QF 162
           P      RG  GA G   F   P P  P     G +PG         +  L        F
Sbjct: 577 PAGPAGERGEQGAPGPSGFQGLPGP--PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634

Query: 163 ANSRVSLGTHRI--------GEGVGGEKRQE--AGSPGWNPGLGLARL-GSYSTVCLA-- 209
              R S G   +          G  G K     AG PG     GL  + G      +A  
Sbjct: 635 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 694

Query: 210 -----------PELAFGLGGVLRVSGPATPELALRSRA----VTPPS-LGGGGDRGENRE 253
                      PE A G  G   ++GP  P     +      V PP   G  G RG   E
Sbjct: 695 KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 754

Query: 254 EGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPGGGKNLGPRLCG 313
            G     GP    P P   A    GA   P  +  Q    + G    PG           
Sbjct: 755 RGE---TGP----PGPAGFA-GPPGADGQPGAKGEQGEAGQKGDAGAPG----------- 795

Query: 314 KSPRGSQTARS-SSPSRAWAPGWRQLGRGP--ATPMLHGLGPVPPPLWAAVSASRWGGGG 370
             P+G   A     P+    P   +  +GP  AT      G V PP       S    G 
Sbjct: 796 --PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP------GSNGNPGP 847

Query: 371 PQPLPQVSKEGSGLARPDPSCCVRAG----LGAAKTPGAQGE-----------RLGPRGT 415
           P P     K+G   AR D     RAG     G A  PG +GE             GP+G 
Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907

Query: 416 RRARGLQLRPVGGQSRREAAPACSGP--QPCRPHGTGAASSLG 456
              RG+   P  GQ      P   GP  +P +    GA+   G
Sbjct: 908 AGQRGIVGLP--GQRGERGFPGLPGPSGEPGKQGAPGASGDRG 948



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 118/457 (25%), Positives = 154/457 (33%), Gaps = 85/457 (18%)

Query: 59  PWPPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPR 118
           P PP P       AA    G    +G A+ LG + G  G              PR GPP 
Sbjct: 98  PGPPGPPGLGGNFAAQMAGGFDEKAGGAQ-LGVMQGPMGPM-----------GPR-GPP- 143

Query: 119 GAVGAAGAQDF---------------LNPR-----PLWPNLDLPGLRPGKITASARPSSQ 158
           G  GA G Q F               + PR     P  P  D    +PGK      P  Q
Sbjct: 144 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 159 ALQ-FANSRVSLGT--HRIGEGVGGEKRQ--------EAGSPGWN--PGLGLARLGSYST 205
             + F  +    G   HR   G+ G K +        E+GSPG N  PG    R      
Sbjct: 204 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 263

Query: 206 VCLAPELAFGLGGVLRVSGPATPELAL--------------RSRAVTPPSLGGGGDRGEN 251
               P  A G  G     GPA P   +              +  A    + G  G +G  
Sbjct: 264 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 323

Query: 252 REEGRDLCLGPVAKKPDPRALAI-SSRGAAASPCLQVAQQSFLELGAQKTPGGGKNLGPR 310
            E G     GP     +P    I  ++G+A +P +  A       G     G    LGP+
Sbjct: 324 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 383

Query: 311 LCGKSP-----RGSQTARS----SSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAV 361
                P     +G Q  +     + P  A  P   +  RG A     G+GP+ PP     
Sbjct: 384 GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG-ARGEPGGVGPIGPP----- 437

Query: 362 SASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGE--RLGPRGTRRAR 419
                G  G +  P       GLA P  +   R   G A   GA G+  R G  G   AR
Sbjct: 438 --GERGAPGNRGFPGQD----GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491

Query: 420 GLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLG 456
           GL  RP     + +  P+ +  +  RP   G   + G
Sbjct: 492 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG 528



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 53/207 (25%), Positives = 66/207 (31%), Gaps = 34/207 (16%)

Query: 243  GGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPG 302
            G  G  G   E G     GP  +K +P     S       P     Q+  + L  Q+   
Sbjct: 864  GDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGER 923

Query: 303  GGKNL-GPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAV 361
            G   L GP              S  P +  APG     RGP        GPV PP     
Sbjct: 924  GFPGLPGP--------------SGEPGKQGAPG-ASGDRGPP-------GPVGPPGLTGP 961

Query: 362  SASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGER-----LGPRGTR 416
            +      G P       ++G+   + D     R   GA   PGA G        GP G +
Sbjct: 962  AGEPGREGSPGADGPPGRDGAAGVKGD-----RGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016

Query: 417  RARG-LQLRPVGGQSRREAAPACSGPQ 442
              RG    +   G S    A    GPQ
Sbjct: 1017 GDRGEAGAQGPMGPSGPAGARGIQGPQ 1043


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 94/362 (25%), Positives = 126/362 (34%), Gaps = 44/362 (12%)

Query: 76   EPGPSPSSGLAEKLG--AVAGKKGVFLLIFARLLTFAAPRLGPP----RGAVGAAGAQDF 129
            +PGP  + GLA   G    +G KG                 GPP     G  GA G    
Sbjct: 2184 DPGPPGAPGLAGPAGPQGPSGLKG------------EPGETGPPGRGLTGPTGAVGLPGP 2231

Query: 130  LNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGGEKRQEA--- 186
              P  L      PGL PG++  + +P +     A+ +      R   GV G         
Sbjct: 2232 PGPSGLVGPQGSPGL-PGQVGETGKPGAPGRDGASGKDG---DRGSPGVPGSPGLPGPVG 2287

Query: 187  --GSPGWN--PGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPPSL 242
              G PG    PG  +  L        AP    GL G L     A  +  L          
Sbjct: 2288 PKGEPGPTGAPGQAVVGLPGAKGEKGAPG---GLAGDLVGEPGAKGDRGLPGPRGEKGEA 2344

Query: 243  GGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPG 302
            G  G+ G+  E+G+    GP   K DP      S G    P ++       +LG    PG
Sbjct: 2345 GRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKG------DLGLPGLPG 2398

Query: 303  GGKNLG-PRLCGKSPRGSQTARSSSPSRAWA-PGWRQLGRGPATPMLHGLGPVPPPLWAA 360
                +G P   G  PRG       S  R  A P  R+   GP  P     G V PP  + 
Sbjct: 2399 APGVVGFPGQTG--PRGEMGQPGPSGERGLAGPPGREGIPGPLGPP-GPPGSVGPPGASG 2455

Query: 361  VSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARG 420
            +   +   G   P P+  +   G+   D         G    PG++GER G +G   + G
Sbjct: 2456 LKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGER-GEKGDVGSAG 2514

Query: 421  LQ 422
            L+
Sbjct: 2515 LK 2516



 Score = 35.8 bits (81), Expect = 0.084
 Identities = 80/294 (27%), Positives = 103/294 (35%), Gaps = 57/294 (19%)

Query: 177  GVGGEK--RQEAGSPGWN--PGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELAL 232
            G  GE+  + + G PG    PGL L   G        P    GL G      P  P L  
Sbjct: 1997 GFPGERGLKGDRGDPGPQGPPGLALGERG--------PPGPSGLAG--EPGKPGIPGLPG 2046

Query: 233  RSRAV----TPPSLGGGGDRGENREEGRDLCLG----PVAKKPDPRALAISSRGAAASPC 284
            R+  V     P   G  G++GE  E+GRD   G    P    P    +++   G    P 
Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPG----PG 2102

Query: 285  LQVAQQSFLELGAQKTPGGGKNLGPR----LCG-KSPRGSQTARSSSPSRAWAPGWRQLG 339
            L   Q      GA+  PG   + GP+    + G K  RG    R         PG R + 
Sbjct: 2103 LSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQD-GNPGLPGERGMA 2161

Query: 340  RGPATPMLHG----LGPV-----PPPLWAAVSASRWGGGGPQPLP----QVSKEGSGLAR 386
                 P L G     GPV     P P  A   A   G  GP  L     +    G GL  
Sbjct: 2162 GPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTG 2221

Query: 387  PDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLRPVGGQSRREAAPACSG 440
            P         +G    PG  G  +GP+G+    G       G++ +  AP   G
Sbjct: 2222 P------TGAVGLPGPPGPSG-LVGPQGSPGLPGQV-----GETGKPGAPGRDG 2263


>gi|169169912 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 184

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 51/156 (32%), Positives = 63/156 (40%), Gaps = 14/156 (8%)

Query: 309 PRLCGKSPRG---SQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAVSASR 365
           P   G+  RG   S T R+     + A  W  L  GP      G G VP P  A V A  
Sbjct: 19  PAAPGQRGRGGDISLTHRTVGALPSVARSWGDLQWGPCGAARGGTGRVPAPPRACVCAGS 78

Query: 366 WGG--GGPQPLPQVSKEGSGLARPD--PSCCVRAGLGAAKTPGAQGERLGPRGTRRARGL 421
           W G  G    +P  S    G   P   P+C  RA LG+A++PG      G  G  RA   
Sbjct: 79  WQGHLGRAARVPCASHTHVGGPGPQAGPACGFRA-LGSAQSPG-PATAAGAPGFSRALSP 136

Query: 422 QLRPVGGQSRREAAPACSGP-QPCRPHGTGAASSLG 456
              P G +    AAP    P Q     G+G + S+G
Sbjct: 137 GPVPPGWR----AAPRAGAPHQRAAATGSGGSRSVG 168


>gi|239749005 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 178

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 51/156 (32%), Positives = 63/156 (40%), Gaps = 14/156 (8%)

Query: 309 PRLCGKSPRG---SQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAVSASR 365
           P   G+  RG   S T R+     + A  W  L  GP      G G VP P  A V A  
Sbjct: 13  PAAPGQRGRGGDISLTHRTVGALPSVARSWGDLQWGPCGAARGGTGRVPAPPRACVCAGS 72

Query: 366 WGG--GGPQPLPQVSKEGSGLARPD--PSCCVRAGLGAAKTPGAQGERLGPRGTRRARGL 421
           W G  G    +P  S    G   P   P+C  RA LG+A++PG      G  G  RA   
Sbjct: 73  WQGHLGRAARVPCASHTHVGGPGPQAGPACGFRA-LGSAQSPG-PATAAGAPGFSRALSP 130

Query: 422 QLRPVGGQSRREAAPACSGP-QPCRPHGTGAASSLG 456
              P G +    AAP    P Q     G+G + S+G
Sbjct: 131 GPVPPGWR----AAPRAGAPHQRAAATGSGGSRSVG 162


>gi|239743025 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 178

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 51/156 (32%), Positives = 63/156 (40%), Gaps = 14/156 (8%)

Query: 309 PRLCGKSPRG---SQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAVSASR 365
           P   G+  RG   S T R+     + A  W  L  GP      G G VP P  A V A  
Sbjct: 13  PAAPGQRGRGGDISLTHRTVGALPSVARSWGDLQWGPCGAARGGTGRVPAPPRACVCAGS 72

Query: 366 WGG--GGPQPLPQVSKEGSGLARPD--PSCCVRAGLGAAKTPGAQGERLGPRGTRRARGL 421
           W G  G    +P  S    G   P   P+C  RA LG+A++PG      G  G  RA   
Sbjct: 73  WQGHLGRAARVPCASHTHVGGPGPQAGPACGFRA-LGSAQSPG-PATAAGAPGFSRALSP 130

Query: 422 QLRPVGGQSRREAAPACSGP-QPCRPHGTGAASSLG 456
              P G +    AAP    P Q     G+G + S+G
Sbjct: 131 GPVPPGWR----AAPRAGAPHQRAAATGSGGSRSVG 162


>gi|239757701 PREDICTED: hypothetical protein XP_002345525 [Homo
           sapiens]
          Length = 180

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 47/163 (28%), Positives = 65/163 (39%), Gaps = 29/163 (17%)

Query: 313 GKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAVSASRWGGG-GP 371
           G   RG+  A    P+  WA   R++  G         GP PP L AA   +  G G GP
Sbjct: 23  GMGHRGAMLAVEHPPAGGWARA-REVSPGSGRTACSQCGPTPPALQAAGCPAPPGTGRGP 81

Query: 372 QPLPQVSK-------EGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLR 424
           Q  P +S+        GS L +            AA    A G+ +G   ++++    LR
Sbjct: 82  QRSPPISRMLDTNLLSGSSLQQM-----------AASGKKAGGQSVGTNFSQKS--FTLR 128

Query: 425 PVGGQSRREAAPACSGPQPCRPHGTGAASSL-------GLQDA 460
           P      R++  A + P  CR     AAS L       GLQD+
Sbjct: 129 PKSSVRGRQSGSAYTCPMICRGSDARAASVLPLRVSPPGLQDS 171


>gi|239752186 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 180

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 47/163 (28%), Positives = 65/163 (39%), Gaps = 29/163 (17%)

Query: 313 GKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAVSASRWGGG-GP 371
           G   RG+  A    P+  WA   R++  G         GP PP L AA   +  G G GP
Sbjct: 23  GMGHRGAMLAVEHPPAGGWARA-REVSPGSGRTACSQCGPTPPALQAAGCPAPPGTGRGP 81

Query: 372 QPLPQVSK-------EGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLR 424
           Q  P +S+        GS L +            AA    A G+ +G   ++++    LR
Sbjct: 82  QRSPPISRMLDTNLLSGSSLQQM-----------AASGKKAGGQSVGTNFSQKS--FTLR 128

Query: 425 PVGGQSRREAAPACSGPQPCRPHGTGAASSL-------GLQDA 460
           P      R++  A + P  CR     AAS L       GLQD+
Sbjct: 129 PKSSVRGRQSGSAYTCPMICRGSDARAASVLPLRVSPPGLQDS 171


>gi|239746709 PREDICTED: hypothetical protein XP_002343816 [Homo
           sapiens]
          Length = 180

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 47/163 (28%), Positives = 65/163 (39%), Gaps = 29/163 (17%)

Query: 313 GKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAVSASRWGGG-GP 371
           G   RG+  A    P+  WA   R++  G         GP PP L AA   +  G G GP
Sbjct: 23  GMGHRGAMLAVEHPPAGGWARA-REVSPGSGRTACSQCGPTPPALQAAGCPAPPGTGRGP 81

Query: 372 QPLPQVSK-------EGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLR 424
           Q  P +S+        GS L +            AA    A G+ +G   ++++    LR
Sbjct: 82  QRSPPISRMLDTNLLSGSSLQQM-----------AASGKKAGGQSVGTNFSQKS--FTLR 128

Query: 425 PVGGQSRREAAPACSGPQPCRPHGTGAASSL-------GLQDA 460
           P      R++  A + P  CR     AAS L       GLQD+
Sbjct: 129 PKSSVRGRQSGSAYTCPMICRGSDARAASVLPLRVSPPGLQDS 171


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 110/427 (25%), Positives = 143/427 (33%), Gaps = 74/427 (17%)

Query: 59  PWPP----SPGRRL-----NRPAAVREPGPSPSSGLAEKLG--AVAGKKGVFLLIFARLL 107
           P PP    SPG R       R   +  PG   +SG A   G    AG+ G   L+  R L
Sbjct: 393 PGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGL 452

Query: 108 TFAAPRLGPP--RGAVGAAGAQDFLNPRPLWP--------NLDLPGLRPGKITASARPSS 157
             +   +GP    G VG  G      P P+ P        N+  PG +            
Sbjct: 453 PGSPGNIGPAGKEGPVGLPGIDG--RPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDK 510

Query: 158 QALQFANSRVSLGTHRIG--------EGVGGEKRQEA--GSPGWNPGLGLARLGSYSTVC 207
                A +R + G             +GV G K ++   G PG+    G +  G    V 
Sbjct: 511 GHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPS--GPAGEVG 568

Query: 208 LAPELAFGLGGVLRVSGPATPELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKKP 267
              E   GL G   + GPA P    R     P   G  G  G     G     GP   K 
Sbjct: 569 KPGER--GLHGEFGLPGPAGP----RGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKG 622

Query: 268 DPRAL-AISSRGAAASPCLQVAQQSFLELGAQKTPGG-GKNLGPRLCGKSPRGSQTARSS 325
           +P  + A+ + G +    L        E GA   PGG G+   P L G+     +     
Sbjct: 623 EPGVVGAVGTAGPSGPSGLPG------ERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARG 676

Query: 326 SPSRAWAPGWRQLGRGPATPMLHGLGPVPP--PLWAAVSASRWGGGGPQPLPQVSKEGSG 383
           +P    APG    G           GP  P  P  +       G  GP          +G
Sbjct: 677 APGAVGAPG--PAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGP----------NG 724

Query: 384 LARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLRPVGGQSRREAAPACSGPQP 443
            A P          GAA  PGA+GER G +G +   G+ + P G       A     P P
Sbjct: 725 FAGP---------AGAAGQPGAKGER-GAKGPKGENGV-VGPTGPVGAAGPAGPNGPPGP 773

Query: 444 CRPHGTG 450
               G G
Sbjct: 774 AGSRGDG 780



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 109/383 (28%), Positives = 131/383 (34%), Gaps = 86/383 (22%)

Query: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPR--LGPPR 118
           PP P      P     PGPS  +G   K G   G  G F L        A PR   GPP 
Sbjct: 548 PPGP------PGFQGLPGPSGPAGEVGKPGE-RGLHGEFGLPGP-----AGPRGERGPP- 594

Query: 119 GAVGAAGAQDFLNPRPLW--PNLDLPGLRPGKITA--SARPSSQALQFANSRVSLGTHRI 174
           G  GAAG    +  R     P  D     PG + A  +A PS  +         L   R 
Sbjct: 595 GESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPS--------GLPGERG 646

Query: 175 GEGVGGEKRQEAGSPGW-----NPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPE 229
             G+ G K  E G PG      NPG   AR    +     P  A G  G    +GPA P 
Sbjct: 647 AAGIPGGKG-EKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPA 705

Query: 230 LALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQ 289
                        G  G+RGE    G +   GP               GAA  P  +   
Sbjct: 706 ----------GPRGSPGERGEVGPAGPNGFAGPA--------------GAAGQPGAKG-- 739

Query: 290 QSFLELGAQKTPGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPA--TPML 347
               E GA+   G    +GP      P G+  A  + P+    P   +   GP   T   
Sbjct: 740 ----ERGAKGPKGENGVVGPT----GPVGA--AGPAGPNGPPGPAGSRGDGGPPGMTGFP 789

Query: 348 HGLGPVPPPLWAAVSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAG-LGAAKTPGAQ 406
              G   PP  + +S      G P P     KEG    R D     R G +GA   PG  
Sbjct: 790 GAAGRTGPPGPSGIS------GPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFA 843

Query: 407 GER--------LGPRGTRRARGL 421
           GE+         GP GT   +GL
Sbjct: 844 GEKGPSGEAGTAGPPGTPGPQGL 866



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 106/420 (25%), Positives = 136/420 (32%), Gaps = 83/420 (19%)

Query: 64  PGRRLNRPAAVREPGPSPSSGLAEKLGAV--------AGKKGVFLLIFARLLTFAAPRLG 115
           PG R      V  PGP+ + G    +G V        AG  G              P   
Sbjct: 219 PGER----GRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGF-------------PGAP 261

Query: 116 PPRGAVGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRIG 175
            P+G +GA G      P      + LPGL  G +     P +  L  A     L      
Sbjct: 262 GPKGEIGAVGNAGPAGPAGPRGEVGLPGL-SGPVGPPGNPGANGLTGAKGAAGLPGVAGA 320

Query: 176 EGVGGEKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSR 235
            G+ G +    G PG     G                A G  G++   GPA  +    ++
Sbjct: 321 PGLPGPR----GIPGPVGAAG----------------ATGARGLVGEPGPAGSKGESGNK 360

Query: 236 AVTPPSLGGGGDRGENREEGRDLCLGPV--AKKPDPRALAISSRGAAASPCLQVAQQSFL 293
              P S G  G  G + EEG+    G    A  P P  L    RG+  S  L  A     
Sbjct: 361 G-EPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGL----RGSPGSRGLPGADG--- 412

Query: 294 ELGAQKTPGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPAT--------P 345
             G    PG     GP    + P G     +  P      G R L   P          P
Sbjct: 413 RAGVMGPPGSRGASGPAGV-RGPNGD----AGRPGEPGLMGPRGLPGSPGNIGPAGKEGP 467

Query: 346 M-LHGLGPVPPPLWAAVSASRWGG-GGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTP 403
           + L G+   P P+  A +    G  G P P       G      D      AG   A  P
Sbjct: 468 VGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGK---NGDKGHAGLAGARGAPGP 524

Query: 404 ----GAQGERLGPRGTRRARGLQLRPVGGQSRREAAPACSGP--QPCRPHGTGAASSLGL 457
               GAQG   GP+G +  +G Q  P  G    +  P  SGP  +  +P   G     GL
Sbjct: 525 DGNNGAQGPP-GPQGVQGGKGEQGPP--GPPGFQGLPGPSGPAGEVGKPGERGLHGEFGL 581


>gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 79/293 (26%), Positives = 102/293 (34%), Gaps = 78/293 (26%)

Query: 232 LRSRAVTPPSLGGG--------GDRGENREEGRDLCLGPVAK-----KPDPRALA--ISS 276
           LRSR  T P+ G G        G  GE    G    + PV+      +PDP  L   +  
Sbjct: 96  LRSR--TDPAFGAGPLPLVSRLGHAGERGSPGAG-DVNPVSASSPPGRPDPLLLTTFVFP 152

Query: 277 RGAAASPCLQVAQQSFLELGAQKTPGGGKNLGPRLCGKSPRGSQTAR-SSSPSRA-WAP- 333
            G  ++P      +    LGA +  G    L PRL  + PRG Q+AR + + SRA WA  
Sbjct: 153 PGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRL--QEPRGHQSARRTDTASRAGWATR 210

Query: 334 -------------GWRQL---------------------------GRGPATPMLHGLGPV 353
                        G R+L                           GRGP + +    G V
Sbjct: 211 RAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGV 270

Query: 354 PPPLWAAVSASRWGGGGPQPLPQVSKEGSGLARP-----DPSCCVRAGLGAAKTPGAQGE 408
            PP W   S  R G G  +  PQV + GS  ARP      P+              A   
Sbjct: 271 EPPGW---SRERAGAGLSRDSPQVPRSGS-WARPCREQGHPAVLALQSPAPPSLARAAAR 326

Query: 409 RLGPRGTRRARGLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD 461
           R GP G      + L      + R   P    P P        A + GL+D D
Sbjct: 327 RRGPGGATEPGFVTL------AFRSRLPLLRSPGPEGTSDAARAPAPGLRDRD 373



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 76/291 (26%), Positives = 96/291 (32%), Gaps = 68/291 (23%)

Query: 185 EAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPPSLGG 244
           EA    W    G +  GS   + L+P +    G   R   P         RA   P  G 
Sbjct: 21  EARPGDWERRAGSSLCGSAEALLLSPHVT---GAAQRSPTPG--------RARAAPQQGD 69

Query: 245 GGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPGGG 304
           GG R   RE      LG  +    PR   + SR   A              GA   P   
Sbjct: 70  GGAR---RERAAAESLGTQSATLGPRRGGLRSRTDPA-------------FGAGPLP--- 110

Query: 305 KNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAVSAS 364
             L  RL     RGS  A   +P  A +P       G   P+L      PP      SA 
Sbjct: 111 --LVSRLGHAGERGSPGAGDVNPVSASSPP------GRPDPLLLTTFVFPP---GKTSAP 159

Query: 365 RWGGGGPQPLPQVSKEGSGL-----------------ARPDPSCCVRAGLGAAKTPGAQG 407
           R   GG +  P  +  G+GL                  R D +   RAG    + P  + 
Sbjct: 160 RPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTAS--RAGWATRRAPSRRR 217

Query: 408 ERLGPRGTRRAR---GLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSL 455
               PRG+RR R   G      GG+ +R A     G +    +G G  S L
Sbjct: 218 NFGAPRGSRRLRPDAGKFPEASGGKGQRAA-----GAERVLNNGRGPRSRL 263



 Score = 29.6 bits (65), Expect = 6.0
 Identities = 58/233 (24%), Positives = 77/233 (33%), Gaps = 42/233 (18%)

Query: 71  PAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGAVGAAGAQDFL 130
           P     P PSP       LGA  G           L    +PRL  PRG   A       
Sbjct: 153 PGKTSAPRPSPGGRRGRPLGAARG---------TGLNPGLSPRLQEPRGHQSARRTD--T 201

Query: 131 NPRPLWPNLDLPGLRP--GKITASARPSSQALQF-----ANSRVSLGTHRIGEGVGGEKR 183
             R  W     P  R   G    S R    A +F        + + G  R+     G + 
Sbjct: 202 ASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRS 261

Query: 184 QEAG------SPGWN---PGLGLA-------RLGSYSTVCLAPELAFGLGGVLRVSGPAT 227
           +  G       PGW+    G GL+       R GS++  C       G   VL +  PA 
Sbjct: 262 RLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQ----GHPAVLALQSPAP 317

Query: 228 PELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAA 280
           P LA  +     P  GG  + G      R     P+ + P P   + ++R  A
Sbjct: 318 PSLARAAARRRGP--GGATEPGFVTLAFRSRL--PLLRSPGPEGTSDAARAPA 366


>gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 79/293 (26%), Positives = 102/293 (34%), Gaps = 78/293 (26%)

Query: 232 LRSRAVTPPSLGGG--------GDRGENREEGRDLCLGPVAK-----KPDPRALA--ISS 276
           LRSR  T P+ G G        G  GE    G    + PV+      +PDP  L   +  
Sbjct: 96  LRSR--TDPAFGAGPLPLVSRLGHAGERGSPGAG-DVNPVSASSPPGRPDPLLLTTFVFP 152

Query: 277 RGAAASPCLQVAQQSFLELGAQKTPGGGKNLGPRLCGKSPRGSQTAR-SSSPSRA-WAP- 333
            G  ++P      +    LGA +  G    L PRL  + PRG Q+AR + + SRA WA  
Sbjct: 153 PGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRL--QEPRGHQSARRTDTASRAGWATR 210

Query: 334 -------------GWRQL---------------------------GRGPATPMLHGLGPV 353
                        G R+L                           GRGP + +    G V
Sbjct: 211 RAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLDNGRGPRSRLPGLAGGV 270

Query: 354 PPPLWAAVSASRWGGGGPQPLPQVSKEGSGLARP-----DPSCCVRAGLGAAKTPGAQGE 408
            PP W   S  R G G  +  PQV + GS  ARP      P+              A   
Sbjct: 271 EPPGW---SRERAGAGLSRDSPQVPRSGS-WARPCREQGHPAVLALQSPAPPSLARAAAR 326

Query: 409 RLGPRGTRRARGLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD 461
           R GP G      + L      + R   P    P P        A + GL+D D
Sbjct: 327 RRGPGGATEPGFVTL------AFRSRLPLLRSPGPEGTSDAARAPAPGLRDRD 373



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 76/291 (26%), Positives = 96/291 (32%), Gaps = 68/291 (23%)

Query: 185 EAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPPSLGG 244
           EA    W    G +  GS   + L+P +    G   R   P         RA   P  G 
Sbjct: 21  EARPGDWERRAGSSLCGSAEALLLSPHVT---GAAQRSPTPG--------RARAAPQQGD 69

Query: 245 GGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPGGG 304
           GG R   RE      LG  +    PR   + SR   A              GA   P   
Sbjct: 70  GGAR---RERAAAESLGTQSATLGPRRGGLRSRTDPA-------------FGAGPLP--- 110

Query: 305 KNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAVSAS 364
             L  RL     RGS  A   +P  A +P       G   P+L      PP      SA 
Sbjct: 111 --LVSRLGHAGERGSPGAGDVNPVSASSPP------GRPDPLLLTTFVFPP---GKTSAP 159

Query: 365 RWGGGGPQPLPQVSKEGSGL-----------------ARPDPSCCVRAGLGAAKTPGAQG 407
           R   GG +  P  +  G+GL                  R D +   RAG    + P  + 
Sbjct: 160 RPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTAS--RAGWATRRAPSRRR 217

Query: 408 ERLGPRGTRRAR---GLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSL 455
               PRG+RR R   G      GG+ +R A     G +    +G G  S L
Sbjct: 218 NFGAPRGSRRLRPDAGKFPEASGGKGQRAA-----GAERVLDNGRGPRSRL 263



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 58/233 (24%), Positives = 78/233 (33%), Gaps = 42/233 (18%)

Query: 71  PAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGAVGAAGAQDFL 130
           P     P PSP       LGA  G           L    +PRL  PRG   A       
Sbjct: 153 PGKTSAPRPSPGGRRGRPLGAARG---------TGLNPGLSPRLQEPRGHQSARRTD--T 201

Query: 131 NPRPLWPNLDLPGLRP--GKITASARPSSQALQF-----ANSRVSLGTHRIGEGVGGEKR 183
             R  W     P  R   G    S R    A +F        + + G  R+ +   G + 
Sbjct: 202 ASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLDNGRGPRS 261

Query: 184 QEAG------SPGWN---PGLGLA-------RLGSYSTVCLAPELAFGLGGVLRVSGPAT 227
           +  G       PGW+    G GL+       R GS++  C       G   VL +  PA 
Sbjct: 262 RLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQ----GHPAVLALQSPAP 317

Query: 228 PELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAA 280
           P LA  +     P  GG  + G      R     P+ + P P   + ++R  A
Sbjct: 318 PSLARAAARRRGP--GGATEPGFVTLAFRSRL--PLLRSPGPEGTSDAARAPA 366


>gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 79/293 (26%), Positives = 102/293 (34%), Gaps = 78/293 (26%)

Query: 232 LRSRAVTPPSLGGG--------GDRGENREEGRDLCLGPVAK-----KPDPRALA--ISS 276
           LRSR  T P+ G G        G  GE    G    + PV+      +PDP  L   +  
Sbjct: 96  LRSR--TDPAFGAGPLPLVSRLGHAGERGSPGAG-DVNPVSASSPPGRPDPLLLTTFVFP 152

Query: 277 RGAAASPCLQVAQQSFLELGAQKTPGGGKNLGPRLCGKSPRGSQTAR-SSSPSRA-WAP- 333
            G  ++P      +    LGA +  G    L PRL  + PRG Q+AR + + SRA WA  
Sbjct: 153 PGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRL--QEPRGHQSARRTDTASRAGWATR 210

Query: 334 -------------GWRQL---------------------------GRGPATPMLHGLGPV 353
                        G R+L                           GRGP + +    G V
Sbjct: 211 RAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLDNGRGPRSRLPGLAGGV 270

Query: 354 PPPLWAAVSASRWGGGGPQPLPQVSKEGSGLARP-----DPSCCVRAGLGAAKTPGAQGE 408
            PP W   S  R G G  +  PQV + GS  ARP      P+              A   
Sbjct: 271 EPPGW---SRERAGAGLSRDSPQVPRSGS-WARPCREQGHPAVLALQSPAPPSLARAAAR 326

Query: 409 RLGPRGTRRARGLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDAD 461
           R GP G      + L      + R   P    P P        A + GL+D D
Sbjct: 327 RRGPGGATEPGFVTL------AFRSRLPLLRSPGPEGTSDAARAPAPGLRDRD 373



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 76/291 (26%), Positives = 96/291 (32%), Gaps = 68/291 (23%)

Query: 185 EAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPPSLGG 244
           EA    W    G +  GS   + L+P +    G   R   P         RA   P  G 
Sbjct: 21  EARPGDWERRAGSSLCGSAEALLLSPHVT---GAAQRSPTPG--------RARAAPQQGD 69

Query: 245 GGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPGGG 304
           GG R   RE      LG  +    PR   + SR   A              GA   P   
Sbjct: 70  GGAR---RERAAAESLGTQSATLGPRRGGLRSRTDPA-------------FGAGPLP--- 110

Query: 305 KNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVPPPLWAAVSAS 364
             L  RL     RGS  A   +P  A +P       G   P+L      PP      SA 
Sbjct: 111 --LVSRLGHAGERGSPGAGDVNPVSASSPP------GRPDPLLLTTFVFPP---GKTSAP 159

Query: 365 RWGGGGPQPLPQVSKEGSGL-----------------ARPDPSCCVRAGLGAAKTPGAQG 407
           R   GG +  P  +  G+GL                  R D +   RAG    + P  + 
Sbjct: 160 RPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTAS--RAGWATRRAPSRRR 217

Query: 408 ERLGPRGTRRAR---GLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSL 455
               PRG+RR R   G      GG+ +R A     G +    +G G  S L
Sbjct: 218 NFGAPRGSRRLRPDAGKFPEASGGKGQRAA-----GAERVLDNGRGPRSRL 263



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 58/233 (24%), Positives = 78/233 (33%), Gaps = 42/233 (18%)

Query: 71  PAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGAVGAAGAQDFL 130
           P     P PSP       LGA  G           L    +PRL  PRG   A       
Sbjct: 153 PGKTSAPRPSPGGRRGRPLGAARG---------TGLNPGLSPRLQEPRGHQSARRTD--T 201

Query: 131 NPRPLWPNLDLPGLRP--GKITASARPSSQALQF-----ANSRVSLGTHRIGEGVGGEKR 183
             R  W     P  R   G    S R    A +F        + + G  R+ +   G + 
Sbjct: 202 ASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLDNGRGPRS 261

Query: 184 QEAG------SPGWN---PGLGLA-------RLGSYSTVCLAPELAFGLGGVLRVSGPAT 227
           +  G       PGW+    G GL+       R GS++  C       G   VL +  PA 
Sbjct: 262 RLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQ----GHPAVLALQSPAP 317

Query: 228 PELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAA 280
           P LA  +     P  GG  + G      R     P+ + P P   + ++R  A
Sbjct: 318 PSLARAAARRRGP--GGATEPGFVTLAFRSRL--PLLRSPGPEGTSDAARAPA 366


>gi|126352446 elastin isoform d precursor [Homo sapiens]
          Length = 711

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 70/281 (24%), Positives = 103/281 (36%), Gaps = 22/281 (7%)

Query: 63  SPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRLGPPRGAVG 122
           SP  +    A   + G    +  A K  A A + G+   +        AP +G   G VG
Sbjct: 443 SPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPG-VG 501

Query: 123 AAGAQDFLNPRPLWPNLDL-PGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGGE 181
            A          + P + + PG+ PG + A+A+ +++    A  R + G   +G G+ G 
Sbjct: 502 LAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG---LGAGIPG- 557

Query: 182 KRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPPS 241
                G PG   G G+  LG          +  G+ G   V G      A +  A  P  
Sbjct: 558 LGVGVGVPGLGVGAGVPGLG----------VGAGVPGFGAVPGALAAAKAAKYGAAVPGV 607

Query: 242 LGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTP 301
           LGG G  G     G  +  GP A      A A ++  AA    +  A    L +G    P
Sbjct: 608 LGGLGALGGVGIPGGVVGAGPAA----AAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 663

Query: 302 GGG--KNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGR 340
           G G    + P    K+ +    AR         PG   LG+
Sbjct: 664 GVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGK 704



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 102/413 (24%), Positives = 139/413 (33%), Gaps = 71/413 (17%)

Query: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKL--GAVAGKK--GVFLLIFARLLTFAAPRLGP 116
           P  PG  + +P A  +PG  P  GL      G + G +  GV +L          P+   
Sbjct: 127 PSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPG 186

Query: 117 PRGA-VGAAGAQDFLNPRPLWP------------NLDLP--------GLRPGKITASA-- 153
             GA  G  G   F  P+P  P               LP        G  PG +  +A  
Sbjct: 187 VGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 246

Query: 154 ---------RPSSQALQFANSRVSLGTHRIG--EGVGGEKRQEAGSPGWNPGL-GLARLG 201
                     P + A   A +    G    G   GVGG      G PG  PG+ G+A +G
Sbjct: 247 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG--AGVPGVPGAIPGIGGIAGVG 304

Query: 202 SYSTVCLAPELA----FGLGGVLRVSGPATPELALRSRAVTPPSLGGGGDRGENREEGRD 257
           + +    A   A    +G    L   GP      +       P +G  G  G     G  
Sbjct: 305 TPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPGAG 363

Query: 258 LCLGPVAKKPDPRALAISSRGAA---ASPCLQVAQQSFLELGAQKTPGGGKNLGPRLCGK 314
           +    V     P A A ++  AA   A P + V       +GA   PG G  +G      
Sbjct: 364 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG------ 417

Query: 315 SPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVP-PPLWAAVSASRWGGGGPQP 373
                       P  A  PG   +G  P    + G+G  P     AA  A+++G G P  
Sbjct: 418 ----------GIPGVAGVPG---VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA 464

Query: 374 LPQVSKEGSGLARPDPSCCVRAGLGAAKTPG-AQGERLGPRGTRRARGLQLRP 425
               +   +      P   V  G+G A   G A G  L P G   A G+ + P
Sbjct: 465 AAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAP-GVGVAPGVGVAP 516


>gi|126352322 elastin isoform c precursor [Homo sapiens]
          Length = 692

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 53/201 (26%), Positives = 76/201 (37%), Gaps = 20/201 (9%)

Query: 142 PGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGGEKRQEAGSPGWNPGLGLARLG 201
           PG+ PG + A+A+ +++    A  R + G   +G G+ G      G PG   G G+  LG
Sbjct: 503 PGIGPGGVAAAAKSAAKVAAKAQLRAAAG---LGAGIPG-LGVGVGVPGLGVGAGVPGLG 558

Query: 202 SYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPPSLGGGGDRGENREEGRDLCLG 261
                     +  G+ G   V G      A +  A  P  LGG G  G     G  +  G
Sbjct: 559 ----------VGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAG 608

Query: 262 PVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPGGG--KNLGPRLCGKSPRGS 319
           P A      A A ++  AA    +  A    L +G    PG G    + P    K+ +  
Sbjct: 609 PAA----AAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYG 664

Query: 320 QTARSSSPSRAWAPGWRQLGR 340
             AR         PG   LG+
Sbjct: 665 VAARPGFGLSPIFPGGACLGK 685



 Score = 29.6 bits (65), Expect = 6.0
 Identities = 108/435 (24%), Positives = 145/435 (33%), Gaps = 81/435 (18%)

Query: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKL--GAVAGKK--GVFLLIFARLLTFAAPRLGP 116
           P  PG  + +P A  +PG  P  GL      G + G +  GV +L          P+   
Sbjct: 127 PSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPG 186

Query: 117 PRGA-VGAAGAQDFLNPRPLWP------------NLDLP--------GLRPGKITASA-- 153
             GA  G  G   F  P+P  P               LP        G  PG +  +A  
Sbjct: 187 VGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 246

Query: 154 ---------RPSSQALQFANSRVSLGTHRIG--EGVGGEKRQEAGSPGWNPGL-GLARLG 201
                     P + A   A +    G    G   GVGG      G PG  PG+ G+A +G
Sbjct: 247 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG--AGVPGVPGAIPGIGGIAGVG 304

Query: 202 SYSTVCLAPELA----FGLGGVLRVSGPATPELALRSRAVTPPSLGGGGDRGENREEGRD 257
           + +    A   A    +G    L   GP      +       P +G  G  G     G  
Sbjct: 305 TPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPGAG 363

Query: 258 LCLGPVAKKPDPRALAISSRGAA---ASPCLQVAQQSFLELGAQKTPGGGKNLGPRLCGK 314
           +    V     P A A ++  AA   A P + V       +GA   PG G  +G      
Sbjct: 364 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG------ 417

Query: 315 SPRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHGLGPVP-PPLWAAVSASRWG---GGG 370
                       P  A  PG   +G  P    + G+G  P     AA  A+++G   G G
Sbjct: 418 ----------GIPGVAGVPG---VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 464

Query: 371 PQPLPQVS-----KEGSGLARPDPSCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLRP 425
             P   V+       G GLA   P   V  G+G A   G     +GP G   A     + 
Sbjct: 465 VAPGVGVAPGVGVAPGVGLA---PGVGVAPGVGVAPGVGV-APGIGPGGVAAAAKSAAKV 520

Query: 426 VGGQSRREAAPACSG 440
                 R AA   +G
Sbjct: 521 AAKAQLRAAAGLGAG 535


>gi|126352700 elastin isoform b precursor [Homo sapiens]
          Length = 677

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 53/201 (26%), Positives = 76/201 (37%), Gaps = 20/201 (9%)

Query: 142 PGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGGEKRQEAGSPGWNPGLGLARLG 201
           PG+ PG + A+A+ +++    A  R + G   +G G+ G      G PG   G G+  LG
Sbjct: 488 PGIGPGGVAAAAKSAAKVAAKAQLRAAAG---LGAGIPG-LGVGVGVPGLGVGAGVPGLG 543

Query: 202 SYSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPPSLGGGGDRGENREEGRDLCLG 261
                     +  G+ G   V G      A +  A  P  LGG G  G     G  +  G
Sbjct: 544 ----------VGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAG 593

Query: 262 PVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPGGG--KNLGPRLCGKSPRGS 319
           P A      A A ++  AA    +  A    L +G    PG G    + P    K+ +  
Sbjct: 594 PAA----AAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYG 649

Query: 320 QTARSSSPSRAWAPGWRQLGR 340
             AR         PG   LG+
Sbjct: 650 VAARPGFGLSPIFPGGACLGK 670


>gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1297

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 85/352 (24%), Positives = 122/352 (34%), Gaps = 63/352 (17%)

Query: 141 LPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGGEKRQEAGSPGWNPGLGLARL 200
           +P    G +  + + +  A   A  R+  G    GE VG   R +  + G    + +  +
Sbjct: 499 VPATGVGGLVGAGQGAVAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGH---VEVVPV 555

Query: 201 GSYSTVCL-------APE--LAFGLGGVLR-----VSGPATPELALRSRAVTPPSL---- 242
           G    +C+       AP   +   LGG L      V+ PA  E   R R    P      
Sbjct: 556 GQQLAICMLHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGGCWPRRPRRR 615

Query: 243 --GGGGDRGENREE----------GRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQ 290
             GGGG  G   ++             + + P A  P  R       G  A  C QVA  
Sbjct: 616 HGGGGGGGGPGLQDLLGGGHAGGAHGHVVVAPAAAAPTAREGRAGRHGHVAVVCPQVAAG 675

Query: 291 S----------FLELGAQKTPGGGKNLGPRLCGKSPRGS--------QTARSSSPSRAWA 332
           +           L +G     G G+  G     ++ R          Q  R     R   
Sbjct: 676 APVGADLDVSVVLWVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFIQRGRGGLGHRP-L 734

Query: 333 PGWRQLGRGP-ATPMLHGLGPVP-PPLWAAVSASRWGGGGPQPLPQVSKEG-SGLARPDP 389
           PGWR  G GP A P +  LG VP  P   A + ++    G  P+   +    SG  R   
Sbjct: 735 PGWRGQGVGPLAQPSVQVLGRVPRDPAVGAATVAQGPVHGHVPVELTAAAAVSGRGR--- 791

Query: 390 SCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLRPVGGQSRREAAPACSGP 441
              +R GLG   +  A+G ++   G    +G +    GG   R    A  GP
Sbjct: 792 ---LRDGLGRVASVAAEGAQVAWAGAVLVQGHEAGVAGG--ARGGGAAAGGP 838


>gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1297

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 85/352 (24%), Positives = 122/352 (34%), Gaps = 63/352 (17%)

Query: 141 LPGLRPGKITASARPSSQALQFANSRVSLGTHRIGEGVGGEKRQEAGSPGWNPGLGLARL 200
           +P    G +  + + +  A   A  R+  G    GE VG   R +  + G    + +  +
Sbjct: 499 VPATGVGGLVGAGQGAVAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGH---VEVVPV 555

Query: 201 GSYSTVCL-------APE--LAFGLGGVLR-----VSGPATPELALRSRAVTPPSL---- 242
           G    +C+       AP   +   LGG L      V+ PA  E   R R    P      
Sbjct: 556 GQQLAICMLHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGGCWPRRPRRR 615

Query: 243 --GGGGDRGENREE----------GRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQ 290
             GGGG  G   ++             + + P A  P  R       G  A  C QVA  
Sbjct: 616 HGGGGGGGGPGLQDLLGGGHAGGAHGHVVVAPAAAAPTAREGRAGRHGHVAVVCPQVAAG 675

Query: 291 S----------FLELGAQKTPGGGKNLGPRLCGKSPRGS--------QTARSSSPSRAWA 332
           +           L +G     G G+  G     ++ R          Q  R     R   
Sbjct: 676 APVGADLDVSVVLWVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFIQRGRGGLGHRP-L 734

Query: 333 PGWRQLGRGP-ATPMLHGLGPVP-PPLWAAVSASRWGGGGPQPLPQVSKEG-SGLARPDP 389
           PGWR  G GP A P +  LG VP  P   A + ++    G  P+   +    SG  R   
Sbjct: 735 PGWRGQGVGPLAQPSVQVLGRVPRDPAVGAATVAQGPVHGHVPVELTAAAAVSGRGR--- 791

Query: 390 SCCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLRPVGGQSRREAAPACSGP 441
              +R GLG   +  A+G ++   G    +G +    GG   R    A  GP
Sbjct: 792 ---LRDGLGRVASVAAEGAQVAWAGAVLVQGHEAGVAGG--ARGGGAAAGGP 838


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 78/281 (27%), Positives = 106/281 (37%), Gaps = 52/281 (18%)

Query: 138 NLDLPGLR--PGKITASARPSSQALQFANSRVSLGTHRIGEGVGGEKRQEAGS------- 188
           N  +PG +  P +  + A PSS A   + ++   G    G+   G+ +    S       
Sbjct: 45  NGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRL 104

Query: 189 PGWNP-GLGLARLGS-------YSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP 240
           PG  P G  LA +G+       Y     + ++A  L G +++SG   P          PP
Sbjct: 105 PGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSG-MQISGAVAP---------APP 154

Query: 241 S--LGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQ 298
           S  LG G         G     G     P  +A  +S   A   P +Q  Q+S     + 
Sbjct: 155 SSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQ--AQGHPGIQTPQRSAPSQASS 212

Query: 299 KTP--GGGKNL----GPRLCGKS---PRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHG 349
            TP   GG  L    GP L G+S   P  SQ    SSP +A  PG         T M   
Sbjct: 213 FTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPG---------TQMTGP 263

Query: 350 LGPVPP---PLWAAVSASRWGGGGPQPLPQVSKEGSGLARP 387
           LGP+PP   P        + G  GP   PQ +  G   A P
Sbjct: 264 LGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAP 304


>gi|38373669 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 78/281 (27%), Positives = 106/281 (37%), Gaps = 52/281 (18%)

Query: 138 NLDLPGLR--PGKITASARPSSQALQFANSRVSLGTHRIGEGVGGEKRQEAGS------- 188
           N  +PG +  P +  + A PSS A   + ++   G    G+   G+ +    S       
Sbjct: 45  NGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRL 104

Query: 189 PGWNP-GLGLARLGS-------YSTVCLAPELAFGLGGVLRVSGPATPELALRSRAVTPP 240
           PG  P G  LA +G+       Y     + ++A  L G +++SG   P          PP
Sbjct: 105 PGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSG-MQISGAVAP---------APP 154

Query: 241 S--LGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQVAQQSFLELGAQ 298
           S  LG G         G     G     P  +A  +S   A   P +Q  Q+S     + 
Sbjct: 155 SSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQ--AQGHPGIQTPQRSAPSQASS 212

Query: 299 KTP--GGGKNL----GPRLCGKS---PRGSQTARSSSPSRAWAPGWRQLGRGPATPMLHG 349
            TP   GG  L    GP L G+S   P  SQ    SSP +A  PG         T M   
Sbjct: 213 FTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPG---------TQMTGP 263

Query: 350 LGPVPP---PLWAAVSASRWGGGGPQPLPQVSKEGSGLARP 387
           LGP+PP   P        + G  GP   PQ +  G   A P
Sbjct: 264 LGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAP 304


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 104/428 (24%), Positives = 137/428 (32%), Gaps = 59/428 (13%)

Query: 58  QPWPPSPGRRLNRPAAVREPGPSPSSGLAEKLG--AVAGKKGVFLLIFARLLTFAAPRLG 115
           +P PP P     +   +  PGP  ++G   K G   V G  G    +        A   G
Sbjct: 564 RPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGA---VGPAGKDGEAGAQG 620

Query: 116 PPRGAVGAAGAQDFLNP--RPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHR 173
           PP G  G AG +    P   P +  L  P   PG+   + +P  Q +            R
Sbjct: 621 PP-GPAGPAGERGEQGPAGSPGFQGLPGPAGPPGE---AGKPGEQGVPGDLGAPGPSGAR 676

Query: 174 IGEGVGGEKRQE-----AGSPGWN--PGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPA 226
              G  GE+  +     AG  G N  PG   A+  + +      + A GL G+    G A
Sbjct: 677 GERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736

Query: 227 TPELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKKPDPRALAISSRGAAASPCLQ 286
                   R    P  G  G  G++   G    +GP      P     S     A P   
Sbjct: 737 GLPGPKGDRGDAGPK-GADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGP--- 792

Query: 287 VAQQSFLELGAQKTPGGGKNLGP----RLCGKSPRGSQTARSSSPSRAWAPGWRQLGRGP 342
                    GA+  PG     GP       G      Q      P  A A G      GP
Sbjct: 793 --------TGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKG----DAGP 840

Query: 343 ATPMLHGLGPVPPP-----LWAAVSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGL 397
             P     GP  PP     + A  +    G  GP            +  P PS       
Sbjct: 841 PGP----AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS----GNA 892

Query: 398 GAAKTPGAQGER--LGPRGTRRARGL--QLRPVG--GQSRREAAPACSGP--QPCRPHGT 449
           G    PG  G+    GPRG     G   ++ P G  G +  + +P   GP   P  P   
Sbjct: 893 GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQ 952

Query: 450 GAASSLGL 457
           G A   G+
Sbjct: 953 GIAGQRGV 960



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 120/430 (27%), Positives = 144/430 (33%), Gaps = 102/430 (23%)

Query: 55   DFNQPWPPSPGRRLNRPAAVREPGPSPSSGLAEKLGAVAGKKGVFLLIFARLLTFAAPRL 114
            D  +P PP P      P A  +PG     G        AG KG                 
Sbjct: 801  DRGEPGPPGPAGFAGPPGADGQPGAKGEPG-------DAGAKG---------------DA 838

Query: 115  GPPRGAVGAAGAQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQFANSRVSLGTHRI 174
            GPP G  G AG      P P+  N+  PG + G   ++  P +     A  RV       
Sbjct: 839  GPP-GPAGPAGP-----PGPI-GNVGAPGAK-GARGSAGPPGATGFPGAAGRVG------ 884

Query: 175  GEGVGGEKRQEAGSPGWNPGLGLARLGSYSTVCLAPELAFGLGGVLRVSGPATPELALRS 234
              G  G     AG PG  PG               P    G  G    +GPA      R 
Sbjct: 885  PPGPSG----NAGPPG-PPG---------------PAGKEGGKGPRGETGPAG-----RP 919

Query: 235  RAVTPPSLGGGGDRGENREEGRDLCLGPVAK--KPDPRALAISSRGAAASPCLQVAQQSF 292
              V PP  G  G  GE    G D   GP      P P+ +A   RG    P  Q  ++ F
Sbjct: 920  GEVGPP--GPPGPAGEKGSPGAD---GPAGAPGTPGPQGIA-GQRGVVGLPG-QRGERGF 972

Query: 293  L-------ELGAQKTPGGGKNLGP----------RLCGKSPRGSQTARSSSPSRAWAPGW 335
                    E G Q   G     GP             G+S R        SP R  +PG 
Sbjct: 973  PGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGA 1032

Query: 336  R--QLGRGPA-TPMLHGLGPVPPPLWAAVSASRWGGGGPQ-PLPQVSKEGS-GLARPDPS 390
            +  +   GPA  P   G    P P+  A  +   G  GP  P   V   G+ G A P   
Sbjct: 1033 KGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGP--- 1089

Query: 391  CCVRAGLGAAKTPGAQGERLGPRGTRRARGLQLRPVGGQSRREAAPA-CSGPQPCR--PH 447
               +   G     G QG+R G +G R   GLQ  P    S  E  P+  SGP   R  P 
Sbjct: 1090 ---QGPRGDKGETGEQGDR-GIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPG 1145

Query: 448  GTGAASSLGL 457
              GA    GL
Sbjct: 1146 SAGAPGKDGL 1155



 Score = 36.2 bits (82), Expect = 0.064
 Identities = 113/446 (25%), Positives = 140/446 (31%), Gaps = 73/446 (16%)

Query: 61  PPSPGRRLNRPAAVREPGPSPSSGLAEKLG-----------AVAGKKGVFLLIFARLLTF 109
           PP P     +  A  EPGP+   G   + G            VAG KG            
Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG-------PAGER 511

Query: 110 AAPRLGPPRGAVGAAG--------AQDFLNPRPLWPNLDLPGLRPGKITASARPSSQALQ 161
            +P    P+G+ G AG            L   P  P  D     PG      RP      
Sbjct: 512 GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP 571

Query: 162 FANSRVSLGTHRIGEGVGGE--KRQEAGSPGWNPGLGLARLGSYSTVCLAPELA------ 213
            A  +  +      +G  GE  K  E G PG    +G A     +     P  A      
Sbjct: 572 GARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGER 631

Query: 214 -----FGLGGVLRVSGPATP--ELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPVAKK 266
                 G  G   + GPA P  E         P  LG  G  G   E G     G V   
Sbjct: 632 GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERG-VQGP 690

Query: 267 PDPRALAISSRGAAASPCLQVAQQSFLELGAQKTPGGGKNLGPRLCG-KSPRGSQTARSS 325
           P P       RGA  +P    A+    + GA   P  G    P L G    RG+      
Sbjct: 691 PGP----AGPRGANGAPGNDGAKG---DAGAPGAP--GSQGAPGLQGMPGERGAAGLPGP 741

Query: 326 SPSRAWAPGWRQLGRGPATPMLHGL-GPVPPPLWAAVSASRWGGGGPQPLPQVSKEGSGL 384
              R  A G +     P    + GL GP+ PP  A     +   G   P       G+  
Sbjct: 742 KGDRGDA-GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPG 800

Query: 385 ARPDPSCCVRAGL----GAAKTPGAQGE--------RLGPRGTRRARGLQLRPVG--GQS 430
            R +P     AG     GA   PGA+GE          GP G     G    P+G  G  
Sbjct: 801 DRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG-PPGPIGNVGAP 859

Query: 431 RREAAPACSGPQPCRPHGTGAASSLG 456
             + A   +GP    P  TG   + G
Sbjct: 860 GAKGARGSAGP----PGATGFPGAAG 881



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 79/293 (26%), Positives = 105/293 (35%), Gaps = 51/293 (17%)

Query: 187 GSPGWNPGLGLARLGSYSTVCLAPELAFGLG----GVLRVSGPATPELALRSRAVTPPSL 242
           G PG  PGLG    G++     AP+L++G      G + V GP  P    R     P + 
Sbjct: 148 GPPG-PPGLG----GNF-----APQLSYGYDEKSTGGISVPGPMGPS-GPRGLPGPPGAP 196

Query: 243 GGGGDRGENREEGRDLCLGPVAKKPDPRALAISSR-GAAASPCLQVAQQSFLELGAQKTP 301
           G  G +G   E G     GP+  +  P     +   G A  P     +      GA+  P
Sbjct: 197 GPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP 256

Query: 302 G-----------GGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLG-RGPATPMLHG 349
           G           G   L        P G +     SP    APG  Q+G RG   P   G
Sbjct: 257 GTAGLPGMKGHRGFSGLDGAKGDAGPAGPK-GEPGSPGENGAPG--QMGPRG--LPGERG 311

Query: 350 LGPVPPPLWAAVSASRWGGGGPQPLPQVSKEGSGLARPDPSCCVRAGLGAAKTPGAQGER 409
               P P  A  +    G  GP P P      +G A P          G     GA+GE 
Sbjct: 312 RPGAPGPAGARGNDGATGAAGP-PGP------TGPAGPP---------GFPGAVGAKGEA 355

Query: 410 --LGPRGTRRARGLQLRPVGGQSRREAAPACSGPQPCRPHGTGAASSLGLQDA 460
              GPRG+   +G++  P        A PA +     +P   GA  + G+  A
Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408


>gi|169164783 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 396

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 65/238 (27%), Positives = 85/238 (35%), Gaps = 45/238 (18%)

Query: 227 TPELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPV-----AKKPDPRALAISSRGAAA 281
           TP L L    VT P   G    G+ R  G     GP      A+ P PR L    R    
Sbjct: 2   TPTLLL---TVTVPRAAGSA--GQRRAPGLPRSSGPAWAESRARPPRPRGL--EPRHPPG 54

Query: 282 SPCLQVAQQSFLELGAQKTPGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRG 341
           SP L+   ++     +  + G G  +G    G  P G   A      R    G  ++GR 
Sbjct: 55  SPALRPTDRTC----SSSSAGVGGGVGGAQPGSVPLGQHLALE----RGRTLGHGRVGRR 106

Query: 342 PATPMLHGLGPVPPPLWAAVSASRWGGG-GPQPLPQV---------SKEGSGLARPDPSC 391
              P    LG +  P  A V     GG   P  + QV          ++   L       
Sbjct: 107 DPPP----LGLLVNPRVAGVDGLDRGGRLDPAGIGQVLGLGVLGGAGRQRRALGGQALGL 162

Query: 392 CVRAGLGAAKTPGAQGERLGPRGTRRAR----------GLQLRPVGGQSRREAAPACS 439
             + G+GA    G +G  +GP G  RAR          G   R VG  + R A+ ACS
Sbjct: 163 LAQVGIGAGHARGGRGA-VGPAGQHRARLGAAVLRGTAGAPARRVGVVAERAASAACS 219


>gi|169163482 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 396

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 65/238 (27%), Positives = 85/238 (35%), Gaps = 45/238 (18%)

Query: 227 TPELALRSRAVTPPSLGGGGDRGENREEGRDLCLGPV-----AKKPDPRALAISSRGAAA 281
           TP L L    VT P   G    G+ R  G     GP      A+ P PR L    R    
Sbjct: 2   TPTLLL---TVTVPRAAGSA--GQRRAPGLPRSSGPAWAESRARPPRPRGL--EPRHPPG 54

Query: 282 SPCLQVAQQSFLELGAQKTPGGGKNLGPRLCGKSPRGSQTARSSSPSRAWAPGWRQLGRG 341
           SP L+   ++     +  + G G  +G    G  P G   A      R    G  ++GR 
Sbjct: 55  SPALRPTDRTC----SSSSAGVGGGVGGAQPGSVPLGQHLALE----RGRTLGHGRVGRR 106

Query: 342 PATPMLHGLGPVPPPLWAAVSASRWGGG-GPQPLPQV---------SKEGSGLARPDPSC 391
              P    LG +  P  A V     GG   P  + QV          ++   L       
Sbjct: 107 DPPP----LGLLVNPRVAGVDGLDRGGRLDPAGIGQVLGLGVLGGAGRQRRALGGQALGL 162

Query: 392 CVRAGLGAAKTPGAQGERLGPRGTRRAR----------GLQLRPVGGQSRREAAPACS 439
             + G+GA    G +G  +GP G  RAR          G   R VG  + R A+ ACS
Sbjct: 163 LAQVGIGAGHARGGRGA-VGPAGQHRARLGAAVLRGTAGAPARRVGVVAERAASAACS 219


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.137    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,952,469
Number of Sequences: 37866
Number of extensions: 1518088
Number of successful extensions: 7395
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 446
Number of HSP's that attempted gapping in prelim test: 6763
Number of HSP's gapped (non-prelim): 1060
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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