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Search of human proteins with 239751523
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member
A5 [Homo sapiens]
(823 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 1617 0.0
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 1617 0.0
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 1423 0.0
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 1420 0.0
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 1417 0.0
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 1415 0.0
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 459 e-129
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 458 e-128
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 458 e-128
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 370 e-102
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 358 1e-98
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 358 1e-98
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 357 3e-98
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 353 4e-97
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 353 4e-97
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 353 4e-97
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 325 1e-88
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 295 9e-80
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 293 3e-79
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 279 7e-75
gi|153791352 prostate, ovary, testis expressed protein on chromo... 257 3e-68
gi|134133226 protein expressed in prostate, ovary, testis, and p... 256 5e-68
gi|88953571 PREDICTED: similar to protein expressed in prostate,... 253 5e-67
gi|113413200 PREDICTED: similar to protein expressed in prostate... 253 7e-67
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 252 9e-67
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 251 2e-66
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 249 6e-66
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 249 6e-66
gi|52856430 protein expressed in prostate, ovary, testis, and pl... 247 3e-65
gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 245 1e-64
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 1617 bits (4186), Expect = 0.0
Identities = 823/823 (100%), Positives = 823/823 (100%)
Query: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL
Sbjct: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
Query: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
MVEFLLKNKASTHAVDRLR TALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI
Sbjct: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
Query: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC
Sbjct: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
Query: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQ KNVQTLRA
Sbjct: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
Query: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK
Sbjct: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK
Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
Query: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKN FL
Sbjct: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
Query: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV
Sbjct: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
Query: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE
Sbjct: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
Query: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV
Sbjct: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 1617 bits (4186), Expect = 0.0
Identities = 823/823 (100%), Positives = 823/823 (100%)
Query: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL
Sbjct: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
Query: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
MVEFLLKNKASTHAVDRLR TALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI
Sbjct: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
Query: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC
Sbjct: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
Query: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQ KNVQTLRA
Sbjct: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
Query: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK
Sbjct: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK
Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
Query: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKN FL
Sbjct: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
Query: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV
Sbjct: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
Query: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE
Sbjct: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
Query: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV
Sbjct: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 1423 bits (3683), Expect = 0.0
Identities = 728/823 (88%), Positives = 770/823 (93%)
Query: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
MKLFGF SRRGQT GSIDH+YTGSGYRIR SELQKIH+AAVKGDAAE+ERCLARRSGDL
Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHV+VVTLLVNRKCQID+ DKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLL HG +IEALDKD+NTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
Query: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
MVEFLLK KAS+HAVDRLR +ALMLAV+YDS GIVNILLKQ+I+VF QDMCGRDAEDYAI
Sbjct: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
Query: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
S LTKIQQQILEHKK ILK +K DVGSSDESAVSIFHEL VDSL A DD+ L+VA KQC
Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
Query: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
VPEKVSEPL G SH KGNRIVNG+GEGPPAKHPSLKPSTE+EDPAVKGAVQ KNVQTLRA
Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
Query: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
EQALPVASEEEQ+R ERSEKKQPQV EGNNT KSEKIQLSENIC ST SAAA RLTQQRK
Sbjct: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNML+KKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
PTVQSLEMK KTARNTPN+DFHNHEE+K LMDENCILK DIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
KYLKDIKI KETNAALEK IKLNEEMIT+TAF YQQELNDLKAENTRLN+ELLKEKESKK
Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
Query: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
+LEA+IESYQSRLAAAISKHSE+VKTERNLKLALERT+D+S QV+MSS IS+++D+N FL
Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660
Query: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
TEQLS+ QIKFN LKDKFRKTRD+LRKKSLALETVQNDLSQTQQQ +EMKEMYQ+AEAKV
Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720
Query: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
+ STGKWNCVEERIC LQREN WL QQL DVHQKEDHKEIV NIQRGFIES KKDL+LEE
Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780
Query: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
K+KKLMNE DHLKESLFQYER+K E VVSIKEDKYFQTSRKK+
Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKKI 823
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 1420 bits (3676), Expect = 0.0
Identities = 727/823 (88%), Positives = 768/823 (93%)
Query: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
MKLFGF SRRGQT GSIDH+YTGSGYRIR SELQKIH+AAVKGDAAE+ERCLARRSG+L
Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL 60
Query: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHV+VVTLLVNRKCQID+ DKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLL HG +IEALDKD+NTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
Query: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
MVEFLLK KAS+HAVDRLR +ALMLAV+YDS GIVNILLKQ+I+VF QDMCGRDAEDYAI
Sbjct: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
Query: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
S LTKIQQQILEHKK ILK +K DVGSSDESAVSIFHEL VDSL A DD+ L+VA KQC
Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
Query: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
VPEKVSEPL G SH KGNRIVNG+GEGPPAKHPSLKPSTE+EDPAVKGAVQ KNVQTLRA
Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
Query: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
EQALPVASEEEQQR ERSEKKQPQV EGNNT KSEKIQLSENIC ST SAAA RLTQQRK
Sbjct: 361 EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNML+KKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
PTVQSLEMK KTARNTPN DFHNHEE+K LMDENCILK DIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
KYLKDIKI KETNAALEK IKLNEEMIT+TAF YQQELNDLKAENTRLN+ELLKEKESKK
Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
Query: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
+LEA+IESYQSRLAAAISKHSE+VKTERNLKLALERTQD+S QV+MSS IS+++D+N FL
Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL 660
Query: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
TEQLS+ QIKFN LKDKFRKTRD+LRKKSLALETVQN+LSQTQQQ +EMKEMYQ+AEAKV
Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV 720
Query: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
+ STGKWNCVEERIC LQREN WL QQL DVHQKEDHKEIV NIQRGFIES KKD +LEE
Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE 780
Query: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
K+KKLMNE DHLKESLFQYER+K E VVSIKEDKYFQTSRKK+
Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 1417 bits (3668), Expect = 0.0
Identities = 726/823 (88%), Positives = 768/823 (93%)
Query: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
MKLFGF SRRGQT GSIDH+YTGSGYRIR SELQKIH+AAVKGDAAE+ERCLARRSGDL
Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHV+VVTLLVNRKCQID+ DKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLL HG +IEALDKD+NTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
Query: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
MVEFLLK KAS+HAVDRLR +ALMLAV+YDS GIVNILLKQ+I+VF QDMCGRDAEDYAI
Sbjct: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
Query: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
S LTKIQQQILEHKK ILK +K DVGSSDESAVSIFHEL VDSL A DD+ L+VA KQC
Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
Query: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
VPEKVSEPL G SH KGNRIVNG+GEGPPAKHPSLKPSTE+EDPAVKGAVQ KNVQTLRA
Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
Query: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
EQALPVASEEEQ+R ERSEKKQPQV EGNNT KSEKIQLSENIC ST SAAA RLTQQRK
Sbjct: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNML+KKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
PTVQSLEMK KTARNTPN+DFHNHEE+K LMDENCILK DIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
KYLKDIKI KETNAALEK IKLNEEMIT+TAF YQQELN LKAENTRLN+ELLKEKESKK
Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK 600
Query: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
+LEA+IESYQSRLAAAISKHSE+VKTERNLKLALERT+D+S QV+MSS IS+++D+N FL
Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660
Query: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
TEQLS+ QIKFN LKDKFRKTRD+LRKKSLALETVQNDLSQTQQQ +EMKEMYQ+AEAKV
Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720
Query: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
+ STGKWNCVEERIC LQREN WL QQL DVHQKEDHKEIV NIQRGFIES KKDL+LEE
Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780
Query: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
K+KKLMNE DHLKESLFQYER+K E VVSIKEDKYFQTSRK +
Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 1415 bits (3662), Expect = 0.0
Identities = 725/823 (88%), Positives = 766/823 (93%)
Query: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
MKLFGF SRRGQT GSIDH+YTGSGYRIR SELQKIH+AAVKGDAAE+ERCLARRSGDL
Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLAC SGHV+VVTLLVNRKCQID+ DKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLL HG +IEALDKD+NTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
Query: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
MVEFLLK KAS+HAVDRLR +ALMLAV+YDS GIVNILLKQ+I+VF QDMCGRDAEDYAI
Sbjct: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
Query: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
S LTKIQQQILEHKK ILK +K DVGSSDESAVSIFHEL VDSL A DD+ L+VA KQC
Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
Query: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
VPEKVSEPL G SH KGNRIVNG+GEGPPAKHPSLKPSTE+EDPAVKGAVQ KNVQTLRA
Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
Query: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
EQALPVASEEEQ+R ERSEKKQPQV EGNNT KSEKIQLSENIC ST SAAA RLTQQRK
Sbjct: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNML+KKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
PTVQSLEMK KTARNTPN DFHNHEE+K LMDENCILK DIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
KYLKDIKI KETNAALEK IKLNEEMIT+TAF YQQELNDLKAENTRLN+ELLKEKESKK
Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
Query: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
+LEA+IESYQSRLAAAISKHSE+VKTERNLKLALERT+D+S QV+MSS IS+++ +N FL
Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKAENEFL 660
Query: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
TEQLS+ QIKFN LKDKFRKTRD+LRKKSLALETVQNDLSQTQQQ +EMKEMYQ+AEAKV
Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720
Query: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
+ STGKWNCVEERIC LQREN WL QQL DVHQKEDHKEIV NIQRGFIES KKDL+LEE
Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780
Query: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
K+KKLMNE DHLKESLFQYER+K E VVSIKEDKYFQTSRK +
Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 459 bits (1180), Expect = e-129
Identities = 311/841 (36%), Positives = 463/841 (55%), Gaps = 66/841 (7%)
Query: 22 YTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASGHVK 81
++ GYR+R +L IHKAA+ GD ++ + R DL+ DK++RTAL LACA G
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 82 VVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 142 YSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRLRXT 201
+E+ S+A KLL +G +IEA +D +T LL A+ KKE+MV FLLK K A+D T
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRT 206
Query: 202 ALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHK------ 255
AL+LA S +V LL+ +I+VF QD+ G AEDYA++ + I+ I E+K
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRCK 266
Query: 256 KMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEK--VSEPLRGPS 313
+ N + D+ + E E C S +++++ K+C +K VS +
Sbjct: 267 SLQNSNSEQDLEMTSEGEQERL-EGCESSQPQVEEKM-----KKCRNKKMEVSRNVHADD 320
Query: 314 HGKGN----RIVNGKGEGPPAKHPS----------LKPSTEMEDPAVKGAVQXKN----- 354
N +++ P H S L T E VK + +
Sbjct: 321 SDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDI 380
Query: 355 ---VQTLRAEQALPVASEE------EQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICH 405
+ + LP + +E EQ E + + I+ + C
Sbjct: 381 SGSSEKTSEDDELPYSDDENFMLLIEQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCE 440
Query: 406 ST---FSAAADRLTQQRKI----GKTYPQQFPKKLKEEHDRCTLK----QENEEKTNVNM 454
F + ++ +K+ KT Q + L+ + C L+ Q+ EE+
Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500
Query: 455 LHKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDE 513
L++K+ EEL+ E+QY+ + E K Q + T++SLE++ KT R+ NQ+FH HE +DL E
Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560
Query: 514 NCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFW 573
N +++ +IA LR EI T+K+ N E ENKY KDI+I KE N LEK +K NEE +TKT
Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEEALTKTITR 620
Query: 574 YQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLA 633
Y +ELN L ENT LNSEL KEK+S +LE E+ESY+ RLAAA+ H + ++R+L+LA
Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680
Query: 634 LERTQDISEQVKMSSDI-SEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLAL 692
+ T ++E + D S I+ L++QLSK + + L+ + R+ L++K+L +
Sbjct: 681 FQST--VNEWCHLQEDTNSHIQ----ILSQQLSKAESTSSGLETELHYEREALKEKTLHI 734
Query: 693 ETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVH 752
E +Q LS+TQ+++++++ MYQ+ + + K K VE+ + QLQ +N +QQ D
Sbjct: 735 EHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDAR 794
Query: 753 QKEDHKE-IVINIQ---RGFIESRKKDL-MLEEKNKKLMNEYDHLKESLFQYERQKAETV 807
+K D++E +INIQ +E + + LEE NK LM E LKE QYE++K E
Sbjct: 795 KKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEERE 854
Query: 808 V 808
V
Sbjct: 855 V 855
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 458 bits (1178), Expect = e-128
Identities = 309/841 (36%), Positives = 464/841 (55%), Gaps = 66/841 (7%)
Query: 22 YTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASGHVK 81
++ GYR+R +L IHKAA+ GD ++ + R DL+ DK++RTAL LACA G
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 82 VVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 142 YSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRLRXT 201
+E+ S+A KLL +G +IEA +D +T LL A+ KKE+MV FLLK K A+D T
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 202 ALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEH------K 255
AL+LA S +V LL+ +I+VF QD+ G AEDYA++ + I+ I E+ K
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266
Query: 256 KMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEK--VSEPLRGPS 313
+ N + D+ + E E C S +++++ K+C +K VS +
Sbjct: 267 SLQNSNSEQDLEMTSEGEQERL-EGCESSQPQVEEKM-----KKCRNKKMEVSRNVHADD 320
Query: 314 HGKGN----RIVNGKGEGPPAKHPS----------LKPSTEMEDPAVKGAVQXKN----- 354
N +++ P H S L T E VK + +
Sbjct: 321 SDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDI 380
Query: 355 ---VQTLRAEQALPVASEEEQQRRERSE----KKQPQVIEGNNTYKSEKIQLSENICHST 407
+ + LP + +E + K + + N + + + C+
Sbjct: 381 SGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCE 440
Query: 408 -----FSAAADRLTQQRKI----GKTYPQQFPKKLKEEHDRCTLK----QENEEKTNVNM 454
F + ++ +K+ KT Q + L+ + C L+ Q+ EE+
Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500
Query: 455 LHKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDE 513
L++K+ EEL+ E+QY+ + E K Q + T++SLE++ KT R+ NQ+FH HE +DL E
Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560
Query: 514 NCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFW 573
N +++ +IA LR EI T+K+ N E ENKY KDI+I KE N LEK +K NEE +TKT
Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620
Query: 574 YQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLA 633
Y +ELN L ENT LNSEL KEK+S +LE E+ESY+ RLAAA+ H + ++R+L+LA
Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680
Query: 634 LERTQDISEQVKMSSDI-SEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLAL 692
+ T ++E + D S I+ L++QLSK + + L+ + R+ L++K+L +
Sbjct: 681 FQST--VNEWCHLQEDTNSHIQ----ILSQQLSKAESTSSGLETELHYEREALKEKTLHI 734
Query: 693 ETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVH 752
E +Q LS+TQ+++++++ MYQ+ + + K K VE+ + QLQ +N +QQ D
Sbjct: 735 EHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDAR 794
Query: 753 QKEDHKE-IVINIQ---RGFIESRKKDL-MLEEKNKKLMNEYDHLKESLFQYERQKAETV 807
+K D++E +INIQ +E + + LEE NK LM E LKE QYE++K E
Sbjct: 795 KKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEERE 854
Query: 808 V 808
V
Sbjct: 855 V 855
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 458 bits (1178), Expect = e-128
Identities = 309/841 (36%), Positives = 464/841 (55%), Gaps = 66/841 (7%)
Query: 22 YTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASGHVK 81
++ GYR+R +L IHKAA+ GD ++ + R DL+ DK++RTAL LACA G
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 82 VVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 142 YSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRLRXT 201
+E+ S+A KLL +G +IEA +D +T LL A+ KKE+MV FLLK K A+D T
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 202 ALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEH------K 255
AL+LA S +V LL+ +I+VF QD+ G AEDYA++ + I+ I E+ K
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266
Query: 256 KMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEK--VSEPLRGPS 313
+ N + D+ + E E C S +++++ K+C +K VS +
Sbjct: 267 SLQNSNSEQDLEMTSEGEQERL-EGCESSQPQVEEKM-----KKCRNKKMEVSRNVHADD 320
Query: 314 HGKGN----RIVNGKGEGPPAKHPS----------LKPSTEMEDPAVKGAVQXKN----- 354
N +++ P H S L T E VK + +
Sbjct: 321 SDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDI 380
Query: 355 ---VQTLRAEQALPVASEEEQQRRERSE----KKQPQVIEGNNTYKSEKIQLSENICHST 407
+ + LP + +E + K + + N + + + C+
Sbjct: 381 SGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCE 440
Query: 408 -----FSAAADRLTQQRKI----GKTYPQQFPKKLKEEHDRCTLK----QENEEKTNVNM 454
F + ++ +K+ KT Q + L+ + C L+ Q+ EE+
Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500
Query: 455 LHKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDE 513
L++K+ EEL+ E+QY+ + E K Q + T++SLE++ KT R+ NQ+FH HE +DL E
Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560
Query: 514 NCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFW 573
N +++ +IA LR EI T+K+ N E ENKY KDI+I KE N LEK +K NEE +TKT
Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620
Query: 574 YQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLA 633
Y +ELN L ENT LNSEL KEK+S +LE E+ESY+ RLAAA+ H + ++R+L+LA
Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680
Query: 634 LERTQDISEQVKMSSDI-SEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLAL 692
+ T ++E + D S I+ L++QLSK + + L+ + R+ L++K+L +
Sbjct: 681 FQST--VNEWCHLQEDTNSHIQ----ILSQQLSKAESTSSGLETELHYEREALKEKTLHI 734
Query: 693 ETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVH 752
E +Q LS+TQ+++++++ MYQ+ + + K K VE+ + QLQ +N +QQ D
Sbjct: 735 EHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDAR 794
Query: 753 QKEDHKE-IVINIQ---RGFIESRKKDL-MLEEKNKKLMNEYDHLKESLFQYERQKAETV 807
+K D++E +INIQ +E + + LEE NK LM E LKE QYE++K E
Sbjct: 795 KKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEERE 854
Query: 808 V 808
V
Sbjct: 855 V 855
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 370 bits (951), Expect = e-102
Identities = 242/511 (47%), Positives = 306/511 (59%), Gaps = 60/511 (11%)
Query: 265 DVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEKVSEPLRGPSHGKGNRIVNGK 324
DVG SDESAVSI HELCVDSL LDDE LSVA KQCVPEKVSEPLRGPSH KGNRIVNGK
Sbjct: 54 DVGISDESAVSILHELCVDSLPTLDDEDLSVATKQCVPEKVSEPLRGPSHEKGNRIVNGK 113
Query: 325 GEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQ 384
G+GPPAKHPSLKPSTE+EDPAVKGAVQ KNVQTLRAEQ LPVA EEEQ+R ERSEKKQ Q
Sbjct: 114 GKGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQTLPVALEEEQERCERSEKKQSQ 173
Query: 385 VIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQ 444
V EGNNT KSEKIQLSEN+CHST SAAADRLT+QRK+GKTYPQQFPKKLK+EHD
Sbjct: 174 VKEGNNTNKSEKIQLSENVCHSTSSAAADRLTKQRKVGKTYPQQFPKKLKKEHD------ 227
Query: 445 ENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQ--DFH 502
REELERKEKQYKKEVEAKQLEPTVQSL+MK KT RNTPNQ
Sbjct: 228 ---------------REELERKEKQYKKEVEAKQLEPTVQSLDMKLKTTRNTPNQINQSL 272
Query: 503 NHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKL 562
+ + K + N D++ +Q+I MK EN K + + E+ +L
Sbjct: 273 RYSQKKVIGFRNS--PNDLSQTQQQIKEMKE---MYENAEAKVNNSTGKWSCVEERICQL 327
Query: 563 NEEMITKTAFWYQQELNDL--KAENTRLNSEL-----------LKEKESKKKLEAEIESY 609
E +Q+L+D+ K ++ + + + L +E KKL E +
Sbjct: 328 QHENPC-----IEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMNECDHL 382
Query: 610 QSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTE-QLSKMQ 668
+ L + +E V R L+ E + + + S + I + L E Q+ K +
Sbjct: 383 KESLFQYEREKAERVVVVRQLQ--QEAADSLKKLTMLESPLEGISHYHINLDETQVPKKK 440
Query: 669 I-KFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
+ + + D F ++ + K + L ++ QQ++ MK++ Q E K
Sbjct: 441 LFQVESQFDDFMAEKEAVSSKCVNL---AKEIQVFQQELLSMKKVQQECE----KLEEDK 493
Query: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHK 758
+EE I L+ +E +V++ + +++K
Sbjct: 494 KMLEEEILNLKTH---MENSMVELSKLQEYK 521
Score = 213 bits (542), Expect = 6e-55
Identities = 128/263 (48%), Positives = 163/263 (61%), Gaps = 26/263 (9%)
Query: 575 QQELNDLKAENT---RLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENV------- 624
++ + L+AE T L E + + S+KK E + + I SENV
Sbjct: 141 RKNVQTLRAEQTLPVALEEEQERCERSEKKQSQVKEGNNTNKSEKIQL-SENVCHSTSSA 199
Query: 625 ---KTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIK--FNTLKDKFR 679
+ + K+ Q +++K D E+E K +++ Q++ +L K +
Sbjct: 200 AADRLTKQRKVGKTYPQQFPKKLKKEHDREELERKEKQYKKEVEAKQLEPTVQSLDMKLK 259
Query: 680 KTRDT----------LRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNC 729
TR+T +KK + NDLSQTQQQIKEMKEMY++AEAKV+ STGKW+C
Sbjct: 260 TTRNTPNQINQSLRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYENAEAKVNNSTGKWSC 319
Query: 730 VEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEY 789
VEERICQLQ ENP +EQQL DVHQKEDHKEIV NIQRGFIES KKDLMLEEKNKKLMNE
Sbjct: 320 VEERICQLQHENPCIEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMNEC 379
Query: 790 DHLKESLFQYERQKAETVVSIKE 812
DHLKESLFQYER+KAE VV +++
Sbjct: 380 DHLKESLFQYEREKAERVVVVRQ 402
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 358 bits (918), Expect = 1e-98
Identities = 271/805 (33%), Positives = 396/805 (49%), Gaps = 120/805 (14%)
Query: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
KL F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+E CL RR DLD
Sbjct: 102 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 161
Query: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
DK+ RT LHLACA G V+VVTLL++RKCQI+I D+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 162 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 221
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
GANPN+KDIYGNTALHYAVY+E TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 222 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 281
Query: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I++ +QDM G+ AEDYA
Sbjct: 282 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 341
Query: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCV 301
C L IQQQILEHK +LKN +D + A K
Sbjct: 342 CDLRSIQQQILEHKNKMLKN------------------------HLRNDNQETAAMK--- 374
Query: 302 PEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAE 361
PE + + K + + + EG A+H +LK ++E
Sbjct: 375 PENLKK-------RKKRKKLKKRKEGAKAEH-NLKVASE--------------------- 405
Query: 362 QALPVASEEEQQRRERSEKKQPQVIEGNNTYKSE---KIQLSENIC---HSTFSAAADRL 415
E+Q+R ERSE KQPQ + K E L +I ++ D L
Sbjct: 406 --------EKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSL 457
Query: 416 TQQRKIGKTYPQ------QFPKKLKEEHDRCTLK--QENEEKTNVNMLHKKNREELERKE 467
+++K + F K ++ + T K Q +++ ++ + + +LE KE
Sbjct: 458 RKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLE-KE 516
Query: 468 KQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQE 527
K K+ +EA+ V+SL TA N + E+ + D +L + R E
Sbjct: 517 KHNKERLEAE-----VESLHSNLATAIN-------EYNEILERKDLELVLWRADDVSRHE 564
Query: 528 ICTMKNDNLEKENKYLKD--IKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAEN 585
L +N+ L + K + N K + + + KT +L DLK
Sbjct: 565 TMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQL-DLKQAQ 623
Query: 586 TRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVK 645
R+ + K I S + EN+ ER L+ A + + +
Sbjct: 624 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 683
Query: 646 MSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQ 705
+ D E K L E+ ++ ++N LK+K + ++ + + Q +L
Sbjct: 684 IHRDCLE-NGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEEL------ 736
Query: 706 IKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQ---LVDVHQKEDHK---- 758
+ +K+ S S C + + W ++ V++ +E H+
Sbjct: 737 VDHLKKFSMSESPLEGTSH----------CHINLDETWTSKKKLFQVEIQPEEKHEEFRK 786
Query: 759 --EIVINIQRGFIESRKKDLMLEEK 781
E++ + + RKK+ LEE+
Sbjct: 787 VFELISLLNYTADQIRKKNRELEEE 811
Score = 328 bits (841), Expect = 1e-89
Identities = 181/374 (48%), Positives = 261/374 (69%), Gaps = 8/374 (2%)
Query: 442 LKQENEEKTNV---NMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPN 498
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 363 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 419
Query: 499 QDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEK 558
QD ++ + KD M N +LK DIA+L++E+ +KND+L KE KY+++IK E NA EK
Sbjct: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 479
Query: 559 CIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAIS 618
++LNEEMITK Y Q+LNDLKAEN RLNS+L KEK +K++LEAE+ES S LA AI+
Sbjct: 480 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539
Query: 619 KHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKF 678
+++E + ++L+L L R D+S M S+IS++ DKN LTEQ+ K ++KFNTLK K
Sbjct: 540 EYNE-ILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 598
Query: 679 RKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQ 738
R+TRD LR+K+LALE+VQ DL Q Q +IKEMK+M+ + EAK S+S GK N EERI Q +
Sbjct: 599 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 658
Query: 739 RENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQ 798
EN LE+QL D ++ D+KEIVINI R +E+ K+DL LEE+NK+LMNEY++LKE L Q
Sbjct: 659 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 717
Query: 799 YERQKAETVVSIKE 812
YE++KAE V ++E
Sbjct: 718 YEKEKAEREVIVRE 731
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 358 bits (918), Expect = 1e-98
Identities = 271/805 (33%), Positives = 396/805 (49%), Gaps = 120/805 (14%)
Query: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
KL F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+E CL RR DLD
Sbjct: 131 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 190
Query: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
DK+ RT LHLACA G V+VVTLL++RKCQI+I D+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 191 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 250
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
GANPN+KDIYGNTALHYAVY+E TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 251 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 310
Query: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I++ +QDM G+ AEDYA
Sbjct: 311 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 370
Query: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCV 301
C L IQQQILEHK +LKN +D + A K
Sbjct: 371 CDLRSIQQQILEHKNKMLKN------------------------HLRNDNQETAAMK--- 403
Query: 302 PEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAE 361
PE + + K + + + EG A+H +LK ++E
Sbjct: 404 PENLKK-------RKKRKKLKKRKEGAKAEH-NLKVASE--------------------- 434
Query: 362 QALPVASEEEQQRRERSEKKQPQVIEGNNTYKSE---KIQLSENIC---HSTFSAAADRL 415
E+Q+R ERSE KQPQ + K E L +I ++ D L
Sbjct: 435 --------EKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSL 486
Query: 416 TQQRKIGKTYPQ------QFPKKLKEEHDRCTLK--QENEEKTNVNMLHKKNREELERKE 467
+++K + F K ++ + T K Q +++ ++ + + +LE KE
Sbjct: 487 RKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLE-KE 545
Query: 468 KQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQE 527
K K+ +EA+ V+SL TA N + E+ + D +L + R E
Sbjct: 546 KHNKERLEAE-----VESLHSNLATAIN-------EYNEILERKDLELVLWRADDVSRHE 593
Query: 528 ICTMKNDNLEKENKYLKD--IKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAEN 585
L +N+ L + K + N K + + + KT +L DLK
Sbjct: 594 TMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQL-DLKQAQ 652
Query: 586 TRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVK 645
R+ + K I S + EN+ ER L+ A + + +
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 712
Query: 646 MSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQ 705
+ D E K L E+ ++ ++N LK+K + ++ + + Q +L
Sbjct: 713 IHRDCLE-NGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEEL------ 765
Query: 706 IKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQ---LVDVHQKEDHK---- 758
+ +K+ S S C + + W ++ V++ +E H+
Sbjct: 766 VDHLKKFSMSESPLEGTSH----------CHINLDETWTSKKKLFQVEIQPEEKHEEFRK 815
Query: 759 --EIVINIQRGFIESRKKDLMLEEK 781
E++ + + RKK+ LEE+
Sbjct: 816 VFELISLLNYTADQIRKKNRELEEE 840
Score = 328 bits (841), Expect = 1e-89
Identities = 181/374 (48%), Positives = 261/374 (69%), Gaps = 8/374 (2%)
Query: 442 LKQENEEKTNV---NMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPN 498
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 392 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 448
Query: 499 QDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEK 558
QD ++ + KD M N +LK DIA+L++E+ +KND+L KE KY+++IK E NA EK
Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 508
Query: 559 CIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAIS 618
++LNEEMITK Y Q+LNDLKAEN RLNS+L KEK +K++LEAE+ES S LA AI+
Sbjct: 509 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 568
Query: 619 KHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKF 678
+++E + ++L+L L R D+S M S+IS++ DKN LTEQ+ K ++KFNTLK K
Sbjct: 569 EYNE-ILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 627
Query: 679 RKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQ 738
R+TRD LR+K+LALE+VQ DL Q Q +IKEMK+M+ + EAK S+S GK N EERI Q +
Sbjct: 628 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 687
Query: 739 RENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQ 798
EN LE+QL D ++ D+KEIVINI R +E+ K+DL LEE+NK+LMNEY++LKE L Q
Sbjct: 688 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 746
Query: 799 YERQKAETVVSIKE 812
YE++KAE V ++E
Sbjct: 747 YEKEKAEREVIVRE 760
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 357 bits (915), Expect = 3e-98
Identities = 270/805 (33%), Positives = 396/805 (49%), Gaps = 120/805 (14%)
Query: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
KL F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+E CL RR DLD
Sbjct: 131 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 190
Query: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
D++ RT LHLACA G V+VVTLL++RKCQI+I D+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 191 VRDRKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 250
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
GANPN+KDIYGNTALHYAVY+E TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 251 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 310
Query: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I++ +QDM G+ AEDYA
Sbjct: 311 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 370
Query: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCV 301
C L IQQQILEHK +LKN +D + A K
Sbjct: 371 CDLRSIQQQILEHKNKMLKN------------------------HLRNDNQETAAMK--- 403
Query: 302 PEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAE 361
PE + + K + + + EG A+H +LK ++E
Sbjct: 404 PENLKK-------RKKRKKLKKRKEGAKAEH-NLKVASE--------------------- 434
Query: 362 QALPVASEEEQQRRERSEKKQPQVIEGNNTYKSE---KIQLSENIC---HSTFSAAADRL 415
E+Q+R ERSE KQPQ + K E L +I ++ D L
Sbjct: 435 --------EKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSL 486
Query: 416 TQQRKIGKTYPQ------QFPKKLKEEHDRCTLK--QENEEKTNVNMLHKKNREELERKE 467
+++K + F K ++ + T K Q +++ ++ + + +LE KE
Sbjct: 487 RKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLE-KE 545
Query: 468 KQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQE 527
K K+ +EA+ V+SL TA N + E+ + D +L + R E
Sbjct: 546 KHNKERLEAE-----VESLHSNLATAIN-------EYNEILERKDLELVLWRADDVSRHE 593
Query: 528 ICTMKNDNLEKENKYLKD--IKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAEN 585
L +N+ L + K + N K + + + KT +L DLK
Sbjct: 594 TMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQL-DLKQAQ 652
Query: 586 TRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVK 645
R+ + K I S + EN+ ER L+ A + + +
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 712
Query: 646 MSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQ 705
+ D E K L E+ ++ ++N LK+K + ++ + + Q +L
Sbjct: 713 IHRDCLE-NGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEEL------ 765
Query: 706 IKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQ---LVDVHQKEDHK---- 758
+ +K+ S S C + + W ++ V++ +E H+
Sbjct: 766 VDHLKKFSMSESPLEGTSH----------CHINLDETWTSKKKLFQVEIQPEEKHEEFRK 815
Query: 759 --EIVINIQRGFIESRKKDLMLEEK 781
E++ + + RKK+ LEE+
Sbjct: 816 VFELISLLNYTADQIRKKNRELEEE 840
Score = 328 bits (841), Expect = 1e-89
Identities = 181/374 (48%), Positives = 261/374 (69%), Gaps = 8/374 (2%)
Query: 442 LKQENEEKTNV---NMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPN 498
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 392 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 448
Query: 499 QDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEK 558
QD ++ + KD M N +LK DIA+L++E+ +KND+L KE KY+++IK E NA EK
Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 508
Query: 559 CIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAIS 618
++LNEEMITK Y Q+LNDLKAEN RLNS+L KEK +K++LEAE+ES S LA AI+
Sbjct: 509 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 568
Query: 619 KHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKF 678
+++E + ++L+L L R D+S M S+IS++ DKN LTEQ+ K ++KFNTLK K
Sbjct: 569 EYNE-ILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 627
Query: 679 RKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQ 738
R+TRD LR+K+LALE+VQ DL Q Q +IKEMK+M+ + EAK S+S GK N EERI Q +
Sbjct: 628 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 687
Query: 739 RENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQ 798
EN LE+QL D ++ D+KEIVINI R +E+ K+DL LEE+NK+LMNEY++LKE L Q
Sbjct: 688 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 746
Query: 799 YERQKAETVVSIKE 812
YE++KAE V ++E
Sbjct: 747 YEKEKAEREVIVRE 760
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 353 bits (906), Expect = 4e-97
Identities = 306/936 (32%), Positives = 461/936 (49%), Gaps = 133/936 (14%)
Query: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
KLF F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+ERCL RR DLD
Sbjct: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
Query: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
A D++ RT LHLACA G V+VVTLL++R+CQIDI D+ NRTPL++AVH QEEACA++LLE
Sbjct: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
GANPN++DIYGNTALHYAVY++ TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
Query: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I + +QDM G+ AEDYA+
Sbjct: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
Query: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQ-- 299
L I+QQILEHK +LKN + + E+A L A + L VA+++
Sbjct: 350 SDLRSIRQQILEHKNKMLKNHLRN--DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 407
Query: 300 --CVPEKVSEPLRGPSHGKGNRIVNG-----------KGEGPPAKHPSL----------K 336
+ +P S+GK + G K E K+ SL K
Sbjct: 408 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 467
Query: 337 PSTEMEDPAVKG------------AVQXKNVQTLRAEQA-LPVASEEEQQRRERSEKKQP 383
TE+ K A + + L+AE A L E+E+ +ER E +
Sbjct: 468 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 527
Query: 384 QVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK 443
+ T +E ++ E AD +++ K+G Q L ++++ T +
Sbjct: 528 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQ-----LTDKNELLT-E 581
Query: 444 QENEEKTNVNMLHKKNRE---------------ELERKEKQYKKEVEAKQLEPTVQSLEM 488
Q ++ + N L K RE +L+ ++ Q++ + E KQ+ P ++ E
Sbjct: 582 QVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIK-EMKQMHPNGEAKES 640
Query: 489 KPKTARNTPNQDFHNHE--------EVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
+ +N+ + E +++D E + I I R + K D LE+ N
Sbjct: 641 QSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERN 700
Query: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAF--WYQQELND-LKA---------ENTRL 588
K ++ KE N EK ++ +E + +Q+EL D LK +
Sbjct: 701 K-----ELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHC 755
Query: 589 NSELLKEKESKKKL-EAEIE---------------SYQSRLAAAISKHSENVKTE-RNLK 631
+ L + SKKKL + EI+ S + A I K + ++ E K
Sbjct: 756 HINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYK 815
Query: 632 LALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFR------------ 679
LE T ++ + D S D N T+QL KM I F LK KF
Sbjct: 816 KCLEMTINMLNAF-ANEDFSCHGDLN---TDQL-KMDILFKKLKQKFNDLVAEKEAVSSE 870
Query: 680 -----KTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERI 734
K + L ++ L++ VQ + ++ K ++E + + + K + ++E
Sbjct: 871 CVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYK 930
Query: 735 CQLQRENPWLEQQLVDVH---QKEDHKEIVINIQRGFIESRKKDLMLEE---KNKKLMNE 788
+L ++L ++H Q E K++ + +KK+L L++ K K+
Sbjct: 931 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 990
Query: 789 YDHLKESLFQYERQKAETV-VSIKEDKYFQTSRKKV 823
Y+ + L +++ A V + K S KK+
Sbjct: 991 YEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKI 1026
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 353 bits (906), Expect = 4e-97
Identities = 306/936 (32%), Positives = 461/936 (49%), Gaps = 133/936 (14%)
Query: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
KLF F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+ERCL RR DLD
Sbjct: 3 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 62
Query: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
A D++ RT LHLACA G V+VVTLL++R+CQIDI D+ NRTPL++AVH QEEACA++LLE
Sbjct: 63 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 122
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
GANPN++DIYGNTALHYAVY++ TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 123 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 182
Query: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I + +QDM G+ AEDYA+
Sbjct: 183 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 242
Query: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQ-- 299
L I+QQILEHK +LKN + + E+A L A + L VA+++
Sbjct: 243 SDLRSIRQQILEHKNKMLKNHLRN--DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 300
Query: 300 --CVPEKVSEPLRGPSHGKGNRIVNG-----------KGEGPPAKHPSL----------K 336
+ +P S+GK + G K E K+ SL K
Sbjct: 301 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 360
Query: 337 PSTEMEDPAVKG------------AVQXKNVQTLRAEQA-LPVASEEEQQRRERSEKKQP 383
TE+ K A + + L+AE A L E+E+ +ER E +
Sbjct: 361 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 420
Query: 384 QVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK 443
+ T +E ++ E AD +++ K+G Q L ++++ T +
Sbjct: 421 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQ-----LTDKNELLT-E 474
Query: 444 QENEEKTNVNMLHKKNRE---------------ELERKEKQYKKEVEAKQLEPTVQSLEM 488
Q ++ + N L K RE +L+ ++ Q++ + E KQ+ P ++ E
Sbjct: 475 QVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIK-EMKQMHPNGEAKES 533
Query: 489 KPKTARNTPNQDFHNHE--------EVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
+ +N+ + E +++D E + I I R + K D LE+ N
Sbjct: 534 QSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERN 593
Query: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAF--WYQQELND-LKA---------ENTRL 588
K ++ KE N EK ++ +E + +Q+EL D LK +
Sbjct: 594 K-----ELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHC 648
Query: 589 NSELLKEKESKKKL-EAEIE---------------SYQSRLAAAISKHSENVKTE-RNLK 631
+ L + SKKKL + EI+ S + A I K + ++ E K
Sbjct: 649 HINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYK 708
Query: 632 LALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFR------------ 679
LE T ++ + D S D N T+QL KM I F LK KF
Sbjct: 709 KCLEMTINMLNAF-ANEDFSCHGDLN---TDQL-KMDILFKKLKQKFNDLVAEKEAVSSE 763
Query: 680 -----KTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERI 734
K + L ++ L++ VQ + ++ K ++E + + + K + ++E
Sbjct: 764 CVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYK 823
Query: 735 CQLQRENPWLEQQLVDVH---QKEDHKEIVINIQRGFIESRKKDLMLEE---KNKKLMNE 788
+L ++L ++H Q E K++ + +KK+L L++ K K+
Sbjct: 824 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 883
Query: 789 YDHLKESLFQYERQKAETV-VSIKEDKYFQTSRKKV 823
Y+ + L +++ A V + K S KK+
Sbjct: 884 YEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKI 919
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 353 bits (906), Expect = 4e-97
Identities = 306/936 (32%), Positives = 461/936 (49%), Gaps = 133/936 (14%)
Query: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
KLF F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+ERCL RR DLD
Sbjct: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
Query: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
A D++ RT LHLACA G V+VVTLL++R+CQIDI D+ NRTPL++AVH QEEACA++LLE
Sbjct: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
GANPN++DIYGNTALHYAVY++ TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
Query: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I + +QDM G+ AEDYA+
Sbjct: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
Query: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQ-- 299
L I+QQILEHK +LKN + + E+A L A + L VA+++
Sbjct: 350 SDLRSIRQQILEHKNKMLKNHLRN--DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 407
Query: 300 --CVPEKVSEPLRGPSHGKGNRIVNG-----------KGEGPPAKHPSL----------K 336
+ +P S+GK + G K E K+ SL K
Sbjct: 408 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 467
Query: 337 PSTEMEDPAVKG------------AVQXKNVQTLRAEQA-LPVASEEEQQRRERSEKKQP 383
TE+ K A + + L+AE A L E+E+ +ER E +
Sbjct: 468 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 527
Query: 384 QVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK 443
+ T +E ++ E AD +++ K+G Q L ++++ T +
Sbjct: 528 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQ-----LTDKNELLT-E 581
Query: 444 QENEEKTNVNMLHKKNRE---------------ELERKEKQYKKEVEAKQLEPTVQSLEM 488
Q ++ + N L K RE +L+ ++ Q++ + E KQ+ P ++ E
Sbjct: 582 QVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIK-EMKQMHPNGEAKES 640
Query: 489 KPKTARNTPNQDFHNHE--------EVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
+ +N+ + E +++D E + I I R + K D LE+ N
Sbjct: 641 QSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERN 700
Query: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAF--WYQQELND-LKA---------ENTRL 588
K ++ KE N EK ++ +E + +Q+EL D LK +
Sbjct: 701 K-----ELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHC 755
Query: 589 NSELLKEKESKKKL-EAEIE---------------SYQSRLAAAISKHSENVKTE-RNLK 631
+ L + SKKKL + EI+ S + A I K + ++ E K
Sbjct: 756 HINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYK 815
Query: 632 LALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFR------------ 679
LE T ++ + D S D N T+QL KM I F LK KF
Sbjct: 816 KCLEMTINMLNAF-ANEDFSCHGDLN---TDQL-KMDILFKKLKQKFNDLVAEKEAVSSE 870
Query: 680 -----KTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERI 734
K + L ++ L++ VQ + ++ K ++E + + + K + ++E
Sbjct: 871 CVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYK 930
Query: 735 CQLQRENPWLEQQLVDVH---QKEDHKEIVINIQRGFIESRKKDLMLEE---KNKKLMNE 788
+L ++L ++H Q E K++ + +KK+L L++ K K+
Sbjct: 931 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 990
Query: 789 YDHLKESLFQYERQKAETV-VSIKEDKYFQTSRKKV 823
Y+ + L +++ A V + K S KK+
Sbjct: 991 YEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKI 1026
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 325 bits (833), Expect = 1e-88
Identities = 195/444 (43%), Positives = 274/444 (61%), Gaps = 62/444 (13%)
Query: 431 KKLKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQ-LEPTVQS 485
+K++ E + C+L+ QE E++ N + L++K RE+L RKE+QY+KEVE KQ LE ++Q+
Sbjct: 780 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT 839
Query: 486 LEMKPKTARNTPNQ---------------------------------------------- 499
LEM+ +T ++ NQ
Sbjct: 840 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE 899
Query: 500 DFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKC 559
+ H+HEE KDL +N +L+ +IA+LR EI T+KN N EKE K +D+KI KE N L+K
Sbjct: 900 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT 959
Query: 560 IKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISK 619
IK NEE +T+T Y L+ L AEN LNS+L EK+SK++LEAE+ESY SRLAAAI
Sbjct: 960 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD 1019
Query: 620 HSENVKTERNLKLALERTQDISE--QVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDK 677
++ ++R L+LA +R +D Q KM+ D+S ++D N L++QL K + K N+L+ +
Sbjct: 1020 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE 1079
Query: 678 FRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQL 737
F TRD LR+K+L LE VQ DLSQTQ Q+KEM++ YQ+ + KV+K GK VEER+ QL
Sbjct: 1080 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL 1139
Query: 738 QRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLMLEEKNKKLMNE 788
Q EN L QQL D H K D+KE VINIQ F ES K+ L+LEE+NK+L++E
Sbjct: 1140 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE 1199
Query: 789 YDHLKESLFQYERQKAETVVSIKE 812
+HLKE +QYE +KAE V +++
Sbjct: 1200 CNHLKERQYQYENEKAEREVVVRQ 1223
Score = 215 bits (547), Expect = 2e-55
Identities = 110/214 (51%), Positives = 151/214 (70%), Gaps = 15/214 (7%)
Query: 8 SRRGQTVLGSI---------------DHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERC 52
S++G++ LGS + Y+ GY +R +L KIHKAA G+ A++++
Sbjct: 6 SKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVAKVQQI 65
Query: 53 LARRSGDLDALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQE 112
L R L+ DK +RTALHLACA+GH +VVTLLV+RKCQ+++ D ENRT L++AV CQE
Sbjct: 66 LLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQE 125
Query: 113 EACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLF 172
E CA ILLEHGA+PNL D++GNTALHYAVY+E S+A KLL + NIEA +KD TPLL
Sbjct: 126 EKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLL 185
Query: 173 AIICKKEKMVEFLLKNKASTHAVDRLRXTALMLA 206
A+ KK++MVEFL+K KA+ +AVD+L + +++
Sbjct: 186 AVSGKKQQMVEFLIKKKANVNAVDKLESSHQLIS 219
Score = 93.6 bits (231), Expect = 7e-19
Identities = 151/672 (22%), Positives = 264/672 (39%), Gaps = 123/672 (18%)
Query: 237 DYAISCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVA 296
D S L + L + + KN++ D+ SA+ + E ++S D E +S
Sbjct: 375 DIIESAPLEQTNNDNLTYVDEVHKNNRSDM----MSALGLGQEEDIES--PWDSESIS-- 426
Query: 297 AKQCVPEKVSEPLRGPSHGKGNRIVNGKGE--------------------------GPPA 330
+ P+K +PL G + GK I N + E G P
Sbjct: 427 --ENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVGMPV 484
Query: 331 KHPS-------LKPSTEMEDPAVKGAVQXKNVQTLRA-EQALPVASEEEQQRRERSEKKQ 382
H LKP+ EM+D A K+VQT +A E L VASEEEQ+R E SE Q
Sbjct: 485 AHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQER-EGSENNQ 543
Query: 383 PQVIEGNNTYKSEKIQLSENICHSTFSAAA-----DRLTQQRKIGKTYPQQFPKKLKEEH 437
PQV E +++ ++++S NI A D L Q+RK G+T QQFP+K +E+
Sbjct: 544 PQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKENKEY 603
Query: 438 D-----------RCTLKQENEEKTNVN----------------MLHKKNREELERKEKQY 470
+ T K++ K +VN + + E++ E +
Sbjct: 604 ASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDEGRP 663
Query: 471 KKEV--EAKQLEPTVQSLEMKPKTARN--TPNQDFH-NHEEVKDLM-----------DEN 514
K+ E +++ +QS++ ++ T ++D H K+ M D
Sbjct: 664 TKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSV 723
Query: 515 CILK-TDIAILRQEICTMKNDNLE-----------KENKYLKDIKIAKETNAALEKCIKL 562
+LK D A+ + + +K ++ E K N +++ KE + LE
Sbjct: 724 SLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVE 783
Query: 563 NEEMITKTAFWYQQELNDLKAENTRLNS--ELLKEKESKKKLEAEIESYQSRLAAAISKH 620
E + F QE + +T E L+ KE + + E E++ +
Sbjct: 784 WERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEME 843
Query: 621 SENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM------QIKFNTL 674
VK+ NL ++ D Q+ + ++D LT LSK Q K N+
Sbjct: 844 LRTVKS--NLNQVVQERNDAQRQLSREQNARMLQD--GILTNHLSKQKEIEMAQKKMNSE 899
Query: 675 KDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERI 734
+ L K+ L Q +++ + +I +K Q E K + V+E+
Sbjct: 900 NSHSHEEEKDLSHKNSML---QEEIAMLRLEIDTIKNQNQEKEKKCFEDL---KIVKEKN 953
Query: 735 CQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKE 794
LQ+ E+ L + + + V+ + + S+ ++ ++ + E H +
Sbjct: 954 EDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRL 1013
Query: 795 SLFQYERQKAET 806
+ ++R ++ET
Sbjct: 1014 AAAIHDRDQSET 1025
Score = 57.4 bits (137), Expect = 5e-08
Identities = 103/501 (20%), Positives = 205/501 (40%), Gaps = 55/501 (10%)
Query: 338 STEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQVIEGNNTY-KSEK 396
S E+E + A++ K + R ++ L S+ + Q +E +K Q + ++ N K E
Sbjct: 1075 SLEIEFHHTRDALREKTLGLERVQKDL---SQTQCQMKEMEQKYQNEQVKVNKYIGKQES 1131
Query: 397 IQ------LSEN-ICHSTFSAAADRLTQQRKIGKTYPQQFP---KKLKEEHDRCTLKQEN 446
++ SEN + A ++ + K QF +KL+ E ++ +L E
Sbjct: 1132 VEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEE 1191
Query: 447 EEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE----PTVQSLEMKPKTARNTPNQDFH 502
K ++ + + + + ++ ++EV +QL+ T++ M + T +
Sbjct: 1192 RNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRIN 1251
Query: 503 NHEEVKDLMDENCILKTDI---------AILRQEICTMKNDNLEKENKYLKDIKIAKETN 553
+E +DL + ++ + A+ E LEK+N LK + + K+
Sbjct: 1252 LEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLK-VTVKKQ-- 1308
Query: 554 AALEKCIKLNEEMITKTAFWYQQE-LNDLKAENTRLNSELLKEKESKKKLEAEIESYQSR 612
++K +L + ++ ++E L L L L +E + +LE EI +++
Sbjct: 1309 --MDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNL 1366
Query: 613 LAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFN 672
L K +E E + L+ + Q +M I++++ K LT +L K
Sbjct: 1367 LKMTRKKLNEYENGEFSFHGDLK-----TSQFEMDIQINKLKHKIDDLTAELETAGSKCL 1421
Query: 673 TLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKE------------MYQSAEAKV 720
L K L+++ L+++TVQ + Q+ K++++ M + + K
Sbjct: 1422 HLDTK----NQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQ 1477
Query: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
K + +E +L+ N +L+ Q E +E + +E R KDL E
Sbjct: 1478 YKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESEL 1537
Query: 781 KNKKLMNEYDHLKESLFQYER 801
K E D K L +Y++
Sbjct: 1538 SKIKTSQE-DFNKTELEKYKQ 1557
Score = 35.4 bits (80), Expect = 0.22
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 1/131 (0%)
Query: 137 LHYAVYSESTSLAEKLLFHGEN-IEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAV 195
+H A + + + +++L +N + DK + T L A ++V L+ K +
Sbjct: 50 IHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVC 109
Query: 196 DRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHK 255
D TALM AV ILL+ + D+ G A YA+ + ++L +
Sbjct: 110 DNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYD 169
Query: 256 KMILKNDKPDV 266
I +K D+
Sbjct: 170 ANIEAKNKDDL 180
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 295 bits (756), Expect = 9e-80
Identities = 192/529 (36%), Positives = 290/529 (54%), Gaps = 57/529 (10%)
Query: 328 PPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRE---------RS 378
PP K + +P+ EM+ A++ KN QTLRA+Q P SE +Q++ E R
Sbjct: 817 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFP--SESKQKKVEENSWDSESLRE 874
Query: 379 EKKQPQVIEGNNTYKSEKIQLSENICHST------------------------------- 407
Q V T++ E ++S + ST
Sbjct: 875 TVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKME 934
Query: 408 -----FSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENEEKTNVNMLHKK 458
F +L++ ++I Q K+K E + C TL QE E++ N ++L++K
Sbjct: 935 QMKKKFCVLKKKLSEAKEIKSQLENQ---KVKWEQELCSVRLTLNQEEEKRRNADILNEK 991
Query: 459 NREELERKEKQYKKEVEAKQ-LEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCIL 517
REEL R E+Q++KE+E KQ LE ++ +++ K+ + NQ H HE L+ ENC+L
Sbjct: 992 IREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCML 1051
Query: 518 KTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQE 577
K +IA+L+ EI T+K+ EKENKY +DIKI KE NA L+ +KL EE +TK A Y +
Sbjct: 1052 KKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQ 1111
Query: 578 LNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERT 637
L L AENT L S+L KEK+ K+ LEAEIES+ RLA+A+ H + V + ++ + A
Sbjct: 1112 LKVLIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIA 1170
Query: 638 QDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQN 697
D Q KM+ D+S N L + LS+ Q K +LK D LR+ +L E Q
Sbjct: 1171 GDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQR 1230
Query: 698 DLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDH 757
D +TQ Q+KE + MYQ+ + V+K T + +++++ QLQ +N WL+QQLV H+K D+
Sbjct: 1231 DQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADN 1290
Query: 758 KEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAET 806
K I I F+E + + +L+EKN+++ N +HLK ++QYE++KAET
Sbjct: 1291 KS-KITIDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAET 1338
Score = 213 bits (542), Expect = 6e-55
Identities = 111/225 (49%), Positives = 158/225 (70%), Gaps = 6/225 (2%)
Query: 55 RRSGDLDALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEA 114
+++ +L+ D Q RTALH AC +GH +VVT LV+RKCQ+D+ D E+RTPL++A+ C +EA
Sbjct: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
Query: 115 CAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAI 174
CA IL++ GA+ NL D+YGNTALHYAVYSE S+ KLL HG IE +K S TPLL +I
Sbjct: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSI 124
Query: 175 ICKKEKMVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRD 234
+ E++VEFLL A+ +AV++ + TALMLAV + S IV +LL+Q+++VF D+CG
Sbjct: 125 TKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVT 184
Query: 235 AEDYAISCRLTKIQQQILEHKKMILKN------DKPDVGSSDESA 273
AE YA++C I +QI+E+ + + KN + G+ DE+A
Sbjct: 185 AEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAA 229
Score = 66.6 bits (161), Expect = 9e-11
Identities = 115/528 (21%), Positives = 205/528 (38%), Gaps = 66/528 (12%)
Query: 328 PPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQVIE 387
PP K + +P+TEM+ A++ KN QTLRA++ LP SE +Q+ E + + E
Sbjct: 579 PPGKPSAFEPATEMQKSVPNKALELKNEQTLRADEILP--SESKQKDYEENSWDTESLCE 636
Query: 388 GNNTYKSEKIQLSENICHSTFSAAADRLTQQ------RKIGKTYPQQFPKKLKEEHDRCT 441
T + + L + +L K P K E D T
Sbjct: 637 ---TVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQT 693
Query: 442 LKQENEEKTNV-------------NMLHKKNREEL--------ERKEKQYKKEV-EAKQL 479
K E EK + L KN + L E K+K Y++ +++ L
Sbjct: 694 FKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESL 753
Query: 480 EPTVQSLEMKPKTARNTPNQDFHNH--EEVKD---LMDENCILKTDI---AILRQEICTM 531
TV ++ A + D N EE D + C +K I A+ ++ T
Sbjct: 754 CETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTF 813
Query: 532 KNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSE 591
K + EK + + I++ K + K ++L E + + E K E +SE
Sbjct: 814 KAEPPEKPSAFEPAIEMQK---SVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSE 870
Query: 592 LLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDIS 651
L+E S+K + ++Q + K S ++ +L L+ ++ D
Sbjct: 871 SLRETVSQKDVCVPKATHQKEM----DKISGKLEDSTSLSKILDTVHSCERARELQKDHC 926
Query: 652 EIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKE 711
E T ++ +M+ KF LK K + ++ + + +L + + + +E
Sbjct: 927 EQR------TGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEE 980
Query: 712 MYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKED--HKEIVINIQRGFI 769
++A+ K + +EE+ R+ ++QQL + +D K + N+ +
Sbjct: 981 KRRNADILNEKIREELGRIEEQ----HRKELEVKQQLEQALRIQDIELKSVESNLNQVSH 1036
Query: 770 ESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQ 817
++ +L E N L E LK + + Q E KE+KYF+
Sbjct: 1037 THENENYLLHE-NCMLKKEIAMLKLEIATLKHQYQE-----KENKYFE 1078
Score = 61.2 bits (147), Expect = 4e-09
Identities = 138/621 (22%), Positives = 231/621 (37%), Gaps = 92/621 (14%)
Query: 243 RLTKIQQQILE--HKKMIL---KNDKPDVGSSD-----ESAVSIFHELCVDSLSALDDEL 292
R+T + ++LE KMI K ++D ES E DS S +
Sbjct: 377 RVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFES-- 434
Query: 293 LSVAAKQCVPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQX 352
S + C+PE + + + +N + E PP K + KP+ EM++ A +
Sbjct: 435 -SAKIQVCIPESIYQKVME---------INREVEEPPKKPSAFKPAIEMQNSVPNKAFEL 484
Query: 353 KNVQTLRAEQALPVASEEEQQRRERSEKK-------QPQVIEGNNTYKSEKIQLSENICH 405
KN QTLRA+ P S+++ + + Q V T++ E +++ +
Sbjct: 485 KNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEE 544
Query: 406 STFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV------------- 452
S + T K+ P K E D T K E K +
Sbjct: 545 SPNKDGLLKATCGMKV------SIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPN 598
Query: 453 NMLHKKNREEL--------ERKEKQYKKEV-EAKQLEPTVQSLEM-KPKTARNTPNQDFH 502
L KN + L E K+K Y++ + + L TV ++ PK A +
Sbjct: 599 KALELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKIN 658
Query: 503 NHEE---VKD-LMDENCILKTDI---AILRQEICTMKNDNLEKENKYLKDIKIAKETNAA 555
E VKD L+ NC +K I A+ ++ T K + EK + + I++ K +
Sbjct: 659 GKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQK---SV 715
Query: 556 LEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAA 615
K ++L E + E E + +SE L E S+K + ++Q +
Sbjct: 716 PNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDK 775
Query: 616 AISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSK--------- 666
K E+ + LK +V + + E+ D F E K
Sbjct: 776 INGKLEESPDNDGFLKAPCRM------KVSIPTKALELMDMQTFKAEPPEKPSAFEPAIE 829
Query: 667 MQIKFNTLKDKFRKTRDTLRKKSL-ALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTG 725
MQ K K K TLR + E+ Q + + + ++E + V K+T
Sbjct: 830 MQ-KSVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATH 888
Query: 726 KWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRK-KDLMLEEKNKK 784
+ ++I ++ L + L VH E +E +Q+ E R K +++K
Sbjct: 889 QKEM--DKISGKLEDSTSLSKILDTVHSCERARE----LQKDHCEQRTGKMEQMKKKFCV 942
Query: 785 LMNEYDHLKESLFQYERQKAE 805
L + KE Q E QK +
Sbjct: 943 LKKKLSEAKEIKSQLENQKVK 963
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 293 bits (751), Expect = 3e-79
Identities = 195/556 (35%), Positives = 303/556 (54%), Gaps = 52/556 (9%)
Query: 283 DSLSALDDELLSVAAKQ---CVPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPST 339
D+ S D E++SV+ Q C+PE ++ K + NGK E P K +P+T
Sbjct: 869 DTKSTSDSEIISVSDTQNYECLPEA--------TYQKEIKTTNGKIEESPEKPSHFEPAT 920
Query: 340 EMEDPAVKGAVQXKNVQTLRAEQ--------ALPVASEEEQQRRERSEKKQPQVIEGNNT 391
EM++ ++ KN QTLRA+ ALP + +++ E+ ++ + N
Sbjct: 921 EMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNK 980
Query: 392 YKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENE 447
+ + +LSE A + Q + +K K E + C TL QE E
Sbjct: 981 FCVLQKELSE----------AKEIKSQLE---------NQKAKWEQELCSVRLTLNQEEE 1021
Query: 448 EKTNVNMLHKKNREELERKEKQYKKEVEAKQ-LEPTVQSLEMKPKTARNTPNQDFHNHEE 506
++ NV++L +K R E +Q +K++E KQ LE T++ +++ K+ + NQ H HE
Sbjct: 1022 KRRNVDILKEKIRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHES 1076
Query: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEM 566
DL ENC+LK +IA+L+ E+ T+K+ + KENKY +DIKI +E NA L+ +KL ++
Sbjct: 1077 ENDLFHENCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKT 1136
Query: 567 ITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKT 626
+TK A Y+++L L AENT L S+L KEK+ K+ LE EIES+ RLA+A+ H ++V +
Sbjct: 1137 VTKRASQYREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTS 1195
Query: 627 ERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLR 686
+N +LA D Q M+ D+S N L + L + Q K + K D LR
Sbjct: 1196 RKNQELAFHSAGDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLR 1255
Query: 687 KKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQ 746
+ +L E Q D +TQ Q+K+ + MYQ+ + V K T + +E+++ QL+ +N WL Q
Sbjct: 1256 ENALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQ 1315
Query: 747 QLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAET 806
QLV H+K + ++ INIQ K L EKN+++ N +HLKE + QYE++KAE
Sbjct: 1316 QLVYAHKKVNKSKVTINIQ---FPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAER 1372
Query: 807 VVSIKEDKYFQTSRKK 822
VSIK+ KYF K+
Sbjct: 1373 EVSIKKYKYFSNFLKE 1388
Score = 217 bits (552), Expect = 4e-56
Identities = 171/531 (32%), Positives = 265/531 (49%), Gaps = 63/531 (11%)
Query: 19 DHLYTGSGY-RIRYSELQKIHKAAVKGDAAEMERC-LARRSGDLDALDKQHRTALHLACA 76
+ +YT Y I + +L KIH AA +G ++E+ + ++ +L+ D + RTALH AC
Sbjct: 23 ERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACV 82
Query: 77 SGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTA 136
+GH +VVT LV+RKCQ+++ D E RTPL++A+ C+ EACA IL++ GA+ N D+YGNTA
Sbjct: 83 NGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADLNYVDVYGNTA 142
Query: 137 LHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVD 196
LHYAVYSE+ + LL +G IE +K S TPLL AI + ++ VEFLL A+ +A +
Sbjct: 143 LHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFN 202
Query: 197 RLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHKK 256
+ TALMLA+ S IV +LL+Q+++VF +D+ G AE YA +C + I QQ+LEH +
Sbjct: 203 ESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNYIHQQLLEHIR 262
Query: 257 MILKN------DKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAK---------QCV 301
+ KN + G+ DE+A E D+ +L ++ AA+ QC+
Sbjct: 263 KLPKNPQNTNPEGTSTGTPDEAAP--LAERTPDTAESLLEKTPDEAARLVEGTSAKIQCL 320
Query: 302 PEKVSEPLRGPSHGKGNRIVNGKGEGP-----PAKHPSLKPSTEMEDPAVK----GAVQX 352
+ S + +I+ E PAK S K + E ++ +VK V
Sbjct: 321 GKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEKETSVKTECVAGVTP 380
Query: 353 KNVQTLRAEQALPVASEEEQQRRERSEKKQPQVIE------GNNTYKSE---KIQLSENI 403
+ L + +A ++ + S +E G T ++ K++ N+
Sbjct: 381 NKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRTIENSQCTKVEEDFNL 440
Query: 404 CHSTFSAAADR-------LTQQRKI----GKTYPQQFPKKLKEEHDR-----CTLKQENE 447
S +A + T Q+ I K Q FP + K E D E+
Sbjct: 441 ATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREEDEEYSWDSGSLFESS 500
Query: 448 EKTNV----NMLHK-----KNREELERKEKQYKKEVEAKQLEPTVQSLEMK 489
KT V +M K + EEL K +K VE ++ P ++ E+K
Sbjct: 501 AKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPN-KAFELK 550
Score = 60.5 bits (145), Expect = 6e-09
Identities = 115/555 (20%), Positives = 205/555 (36%), Gaps = 93/555 (16%)
Query: 294 SVAAKQCVPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXK 353
S + C+PE + + + +N + E P K + KP+ EM+ A + K
Sbjct: 500 SAKTQVCIPESMYQKVME---------INREVEELPEKPSAFKPAVEMQKTVPNKAFELK 550
Query: 354 NVQTLRAEQALPVASEEEQQRRERSEKKQP-------QVIEGNNTYKSEKIQLSENICHS 406
N QTLRA Q P S+++ + + P V T++ E LS + S
Sbjct: 551 NEQTLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEES 610
Query: 407 TFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------N 453
+ T RK+ P K E DR T K E+ +K +
Sbjct: 611 PVKDGLLKPTCGRKV------SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNK 664
Query: 454 MLHKKNREELERKEKQ---YKKEVEAKQLEPTVQSLEMKP----KTARNTPNQDFHNHEE 506
L K+RE L+ + K +++ ++LE+K K A+ P++ +E
Sbjct: 665 ALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDE 724
Query: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEM 566
++ D L+T +L+ ++C K + ++ + ++ + + + L+ + +
Sbjct: 725 -ENSWDFESFLET---LLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISL 780
Query: 567 ITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKT 626
K EL + K + + +ES S +++S++ K
Sbjct: 781 PNKAL-------------------ELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKV 821
Query: 627 ERNLKLALERTQDISEQVKMSSDISEIE-----DKNXFLTEQLSKMQIKFNTLKDKFRKT 681
E + L + + + DI IE N T +L + + +T +
Sbjct: 822 EEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISV 881
Query: 682 RDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQREN 741
DT + L T Q ++ T +I+E E E +T N V + +
Sbjct: 882 SDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFE----PATEMQNSVPNKGLE----- 932
Query: 742 PWLEQQLVDVHQKEDHK--EIVINIQRGFIESRKKD-------LMLEEKNK--KLMNEYD 790
W +Q + K + + + +RG KKD M + KNK L E
Sbjct: 933 -WKNKQTLRADSTTLSKILDALPSCERG--RELKKDNCEQITAKMEQTKNKFCVLQKELS 989
Query: 791 HLKESLFQYERQKAE 805
KE Q E QKA+
Sbjct: 990 EAKEIKSQLENQKAK 1004
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 279 bits (714), Expect = 7e-75
Identities = 189/481 (39%), Positives = 273/481 (56%), Gaps = 61/481 (12%)
Query: 396 KIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHD-RCTLKQENEEKTNVNM 454
K++ EN+ S + L++ +K Q + KE +D R LKQENEEK N +M
Sbjct: 662 KLKQMENMV----SVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADM 717
Query: 455 LHKKNREELERKEKQYKKEVEAKQ-LEPTVQSLEMKPKTARN----------------TP 497
L+ K+ E+L KE++ K VE KQ L+ ++ L + +T RN +
Sbjct: 718 LYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSE 777
Query: 498 NQDF---------------------------HNHEEVKDLMDENCILKTDIAILRQEICT 530
QD H H++ KDL E+C+L+ +IA+LR EI T
Sbjct: 778 EQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDT 837
Query: 531 MKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNS 590
+KN N +KE KY +DI+ KE N L+K IKLNEE +T+T Y +LN+L AEN LNS
Sbjct: 838 IKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNS 897
Query: 591 ELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQD--ISEQVKMSS 648
EL K+++++LE E+ESY+ RLAAA+ + + +T R+LKL +RT+ + KM
Sbjct: 898 ELENGKQNQERLEIEMESYRCRLAAAV-RDCDQSQTARDLKLDFQRTRQEWVRLHDKMKV 956
Query: 649 DISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKE 708
D+S ++ KN L+E+LS + K N+L+ + TRD L ++SL LE VQ DLSQTQ Q KE
Sbjct: 957 DMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKE 1016
Query: 709 MKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVIN-IQRG 767
++MYQ ++K+ K K VEER+ QLQ EN L QQL D H+K + +E + IQ
Sbjct: 1017 TEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQ 1076
Query: 768 F--------IESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTS 819
F ES K+ L L+EKNK+LM+EY+HLKE + Q E++KA + + E + S
Sbjct: 1077 FHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPS 1136
Query: 820 R 820
R
Sbjct: 1137 R 1137
Score = 51.6 bits (122), Expect = 3e-06
Identities = 96/477 (20%), Positives = 188/477 (39%), Gaps = 75/477 (15%)
Query: 369 EEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENI------CHSTFSAAADRLTQQRKIG 422
EE QQ ++ + + + E K E +QL +++ S + + LT +G
Sbjct: 493 EELQQDMQKFKNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVG 552
Query: 423 KT---YPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQL 479
QQ P+K EHDR K NE+ N ++ E + + E+ ++
Sbjct: 553 NDDDGLNQQIPRKENGEHDRPADKTSNEKNEVKNQIY----PEADFADSMEPSEIASEDC 608
Query: 480 EPT----------VQSLEMKPKTARNTPN-QD-FHNHEEVKDLMDENC--------ILKT 519
E + ++ L M+ K + + P QD F E + L + +C ++
Sbjct: 609 ELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMEN 668
Query: 520 DIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELN 579
+++L+ E+ K L+ E L+ I+ KE L +K E Y ++
Sbjct: 669 MVSVLQNELSETKKTKLQLE---LQKIEWEKEL-YDLRLALKQENEEKRNADMLYNKDSE 724
Query: 580 DLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTER-NLKLALERTQ 638
L+ +KE+E K +E + +L + + + ++T R NL L ++
Sbjct: 725 QLR----------IKEEECGKVVET-----KQQLKWNLRRLVKELRTVRNNLDLVVQERN 769
Query: 639 DISEQVKMSSDISEIED-------KNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLA 691
D +Q+ D ++D K + + +I K+K D + ++ +A
Sbjct: 770 DAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIA 829
Query: 692 LETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVE-------ERICQ-------L 737
L ++ D + Q + KE K+ ++ EA K+ ++ E I Q L
Sbjct: 830 LLRLEIDTIKNQNKQKE-KKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNL 888
Query: 738 QRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKE 794
EN L +L + Q ++ EI + R + + +D + + L ++ ++
Sbjct: 889 TAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQ 945
Score = 31.6 bits (70), Expect = 3.1
Identities = 15/32 (46%), Positives = 21/32 (65%)
Query: 353 KNVQTLRAEQALPVASEEEQQRRERSEKKQPQ 384
+N ++ AEQ + SEEEQ+R + E KQPQ
Sbjct: 215 ENKESKEAEQDSELTSEEEQERLKGCENKQPQ 246
>gi|153791352 prostate, ovary, testis expressed protein on
chromosome 2 [Homo sapiens]
Length = 1075
Score = 257 bits (657), Expect = 3e-68
Identities = 197/600 (32%), Positives = 303/600 (50%), Gaps = 80/600 (13%)
Query: 19 DHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASG 78
D + Y +R +L K+H+AA G + + R D++ DKQ RTALHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 79 HVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV LL++R+CQ+++ D + RT LI+AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 139 YAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRL 198
YA+Y+E +A+ LL +G +IE+ +K TPLL + +K+++V+FL+K KA+ +A+DR
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 199 RXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHK-KM 257
TAL+LAV S IV++LL+Q+I+V +QD+ G+ A +YA+S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 258 ILK----NDKPD----VGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEKVSEPL 309
+LK N P+ + S +ES E + + E+ ++ E+ +
Sbjct: 365 MLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREV--EEEMKKH 422
Query: 310 RGPSHGKGNRIVNG--KGEGPPAKHPSLKPST------------------EMEDPAVKGA 349
+ G + NG G G P K T E+ +
Sbjct: 423 ESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQ 482
Query: 350 VQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQ--------------------VIEGN 389
+ + + EQ L + SEEE QR + SE QP+ IE
Sbjct: 483 MPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEM 542
Query: 390 NTYKSEKIQLSENICH-STFSAAADRLTQQRKIGKTYPQQFPKKLKEEH----DRCTLKQ 444
++S + EN+ + +T D L RK QQFP EE+ T KQ
Sbjct: 543 KKHRSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQ 602
Query: 445 ENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNH 504
EE+ N +LH E L +EKQ +E + + SL K +
Sbjct: 603 FCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE------------- 641
Query: 505 EEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNE 564
KD++ EN L+ +IA+LR E+ TMK+ + +E KYL+DI+ K+ N L K ++LNE
Sbjct: 642 ---KDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNLLKALQLNE 698
>gi|134133226 protein expressed in prostate, ovary, testis, and
placenta 2 [Homo sapiens]
Length = 1075
Score = 256 bits (655), Expect = 5e-68
Identities = 197/609 (32%), Positives = 302/609 (49%), Gaps = 98/609 (16%)
Query: 19 DHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASG 78
D + Y +R +L K+H+AA G + + R D++ DKQ RTALHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANG 184
Query: 79 HVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV LL++R+CQ+++ D + RT LI+AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 139 YAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRL 198
YA+Y+E +A+ LL +G +IE+ +K TPLL + +K+++V+FL+K KA+ +A+DR
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 199 RXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHK-KM 257
TAL+LAV S IV++LL+Q+I+V +QD+ G+ A +YA+S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 258 ILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEKVSEPL-------- 309
+LK + E L++ ++ ++ PEK+S+ L
Sbjct: 365 MLKISSENSNPEQEL-----------KLTSEEESQRFKGSENSQPEKMSQELEINKDGDR 413
Query: 310 -------RGPSHGKG--NRIVNG--KGEGPPAKHPSLKPST------------------E 340
+ S+ G + NG G G P K T E
Sbjct: 414 EVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICE 473
Query: 341 MEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQ---------------- 384
+ + + + + EQ L + SEEE QR + SE QP+
Sbjct: 474 LLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDREL 533
Query: 385 ----VIEGNNTYKSEKIQLSENICH-STFSAAADRLTQQRKIGKTYPQQFPKKLKEEH-- 437
IE + S + EN+ + +T D L RK QQFP EE+
Sbjct: 534 ENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHS 593
Query: 438 --DRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARN 495
T KQ EE+ N +LH E L +EKQ +E + + SL K +
Sbjct: 594 DEQNDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE---- 641
Query: 496 TPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAA 555
KD++ EN L+ +IA+LR E+ TMK+ + +E KYL+DI+ K+ N
Sbjct: 642 ------------KDVLHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKKNDN 689
Query: 556 LEKCIKLNE 564
L K ++LNE
Sbjct: 690 LLKALQLNE 698
>gi|88953571 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
Length = 1075
Score = 253 bits (646), Expect = 5e-67
Identities = 196/600 (32%), Positives = 300/600 (50%), Gaps = 80/600 (13%)
Query: 19 DHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASG 78
D + Y +R +L K+H+AA G A + + R D++ DKQ RTALHLA A+G
Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 79 HVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ VV LL++R+CQ+++ D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 139 YAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRL 198
YA+Y+E +A+ LL +G +IE+ +K TPLL + +K+++V+FL+K KA+ +A+DR
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 199 RXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHK-KM 257
TAL+LAV S IV++LL+Q+I+V +QD+ G+ A +YA+S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 258 ILK----NDKPD----VGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEKVSEPL 309
+LK N P+ + S +ES E + + E+ ++ E+ +
Sbjct: 365 MLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREV--EEEMKKH 422
Query: 310 RGPSHGKGNRIVNG--KGEGPPAKHPSLKPST------------------EMEDPAVKGA 349
+ G + NG G G P K T E+ +
Sbjct: 423 ESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQ 482
Query: 350 VQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQ--------------------VIEGN 389
+ + + EQ L + SEEE QR + SE QP+ IE
Sbjct: 483 MPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEM 542
Query: 390 NTYKSEKIQLSENICH-STFSAAADRLTQQRKIGKTYPQQFPKKLKEEH----DRCTLKQ 444
+ S + EN+ + +T D L RK QQFP EE+ T KQ
Sbjct: 543 KKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQ 602
Query: 445 ENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNH 504
EE+ N +LH E L +EKQ +E + + SL K +
Sbjct: 603 FCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE------------- 641
Query: 505 EEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNE 564
KD + EN L+ +IA+LR E+ TMK+ + ++ KYL+DI+ K+ N L K ++LNE
Sbjct: 642 ---KDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLKALQLNE 698
>gi|113413200 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 1038
Score = 253 bits (645), Expect = 7e-67
Identities = 195/600 (32%), Positives = 301/600 (50%), Gaps = 80/600 (13%)
Query: 19 DHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASG 78
D + Y +R +L K+H+AA G A + + R D++ DKQ RTALHLA A+G
Sbjct: 88 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 147
Query: 79 HVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ VV LL++R+CQ+++ D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 148 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207
Query: 139 YAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRL 198
YA+Y+E +A+ LL +G +IE+ +K TPLL + +K+++V+FL+K KA+ +A+DR
Sbjct: 208 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 267
Query: 199 RXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHK-KM 257
TAL+LAV S IV++LL+Q+I+V +QD+ G+ A +YA+S I Q + ++K K
Sbjct: 268 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 327
Query: 258 ILK----NDKPD----VGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEKVSEPL 309
+LK N P+ + S +ES E + + E+ ++ E+ +
Sbjct: 328 MLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREV--EEEMKKH 385
Query: 310 RGPSHGKGNRIVNG--KGEGPPAKHPSLKPST------------------EMEDPAVKGA 349
+ G + NG G G P K T E+ +
Sbjct: 386 ESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQ 445
Query: 350 VQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQ--------------------VIEGN 389
+ + + EQ L + SEEE QR + SE QP+ IE
Sbjct: 446 MPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEM 505
Query: 390 NTYKSEKIQLSENICH-STFSAAADRLTQQRKIGKTYPQQFPKKLKEEH----DRCTLKQ 444
+ S + EN+ + +T D L RK QQFP EE+ T KQ
Sbjct: 506 KKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQ 565
Query: 445 ENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNH 504
EE+ N +LH E L +EKQ +E + + SL K +
Sbjct: 566 FCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE------------- 604
Query: 505 EEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNE 564
+D + EN +L+ +IA+LR E+ TMK+ + ++ KYL+DI+ K+ N L K ++LNE
Sbjct: 605 ---RDFLHENSMLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLKALQLNE 661
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 252 bits (644), Expect = 9e-67
Identities = 190/574 (33%), Positives = 296/574 (51%), Gaps = 95/574 (16%)
Query: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
RI G G P P+LK + E ++ + A + K+VQT AEQ L +ASE EQ+R
Sbjct: 764 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 823
Query: 376 ERSEKKQPQ-------------VIEGNNTYKSE--------------------------- 395
E E QPQ +I+ + T +
Sbjct: 824 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 883
Query: 396 --KI-----------QLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
KI +L +N C + S RL+++ +I +
Sbjct: 884 LLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---T 940
Query: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 941 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 1000
Query: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 1001 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 1057
Query: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
I K + L+K +K NEE + +T Y +L L ENT L S+L K++ES ++LE E++
Sbjct: 1058 IVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ 1117
Query: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
SY+ RL AA+ H ++ ++R+ +LA + T D K + L+ QLSK
Sbjct: 1118 SYRCRLNAALCDHDQSHSSKRDQELAFQGTVD-----KCCHLQENLNSHVLILSLQLSKA 1172
Query: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
+ KF L+ + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 1173 ESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 1231
Query: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 1232 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 1288
Query: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
EE NK L+NE +H KE QYE++KAE V++++
Sbjct: 1289 EEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQ 1322
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 251 bits (641), Expect = 2e-66
Identities = 190/574 (33%), Positives = 295/574 (51%), Gaps = 95/574 (16%)
Query: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
RI G G P P+LK + E ++ + A + K+VQT AEQ L +ASE EQ+R
Sbjct: 202 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 261
Query: 376 ERSEKKQPQ-------------VIEGNNTYKSE--------------------------- 395
E E QPQ +I+ + T +
Sbjct: 262 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 321
Query: 396 --KI-----------QLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
KI +L +N C + S RL+++ +I +
Sbjct: 322 LLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---T 378
Query: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 379 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 438
Query: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 439 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 495
Query: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
I K + L+K +K NEE + +T Y +L L ENT L S+L K++ES ++LE E++
Sbjct: 496 IVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ 555
Query: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
SY+ RL AA+ H ++ ++R+ +LA + T D K + L+ QLSK
Sbjct: 556 SYRCRLNAALCDHDQSHSSKRDQELAFQGTVD-----KCCHLQENLNSHVLILSLQLSKA 610
Query: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
+ KF L+ + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 611 ESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 669
Query: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 670 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 726
Query: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
EE NK L+NE H KE QYE++KAE V++++
Sbjct: 727 EEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQ 760
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 249 bits (637), Expect = 6e-66
Identities = 187/574 (32%), Positives = 293/574 (51%), Gaps = 95/574 (16%)
Query: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
RI G G P P+LK + E ++ + A + K+VQT AEQ L +ASE EQ+R
Sbjct: 858 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 917
Query: 376 ERSEKKQPQV-------------IEGNNTYKSEK-------------------------- 396
E E QPQV I+ + T +
Sbjct: 918 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 977
Query: 397 --------------IQLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
I+L +N C + S R++++ +I +
Sbjct: 978 LLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI--- 1034
Query: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
L+ E + C+L+ QE +++ NV +H+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 1035 LELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 1094
Query: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 1095 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 1151
Query: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
I K + L+K +K N E + KT Y +L L ENT L S+L K++ES+++LE E++
Sbjct: 1152 IVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 1211
Query: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
SY RL AA H ++ ++R+ +LA + T D ++ + L+ QLSK
Sbjct: 1212 SYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKA 1266
Query: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
+ K LK + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 1267 ESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 1325
Query: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 1326 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 1382
Query: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
EE NK L+NE +H KE QYE++KAE V++++
Sbjct: 1383 EEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQ 1416
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 249 bits (637), Expect = 6e-66
Identities = 188/574 (32%), Positives = 292/574 (50%), Gaps = 95/574 (16%)
Query: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
RI G G P +LK + E +D + A + K VQT AEQ L +ASE EQ+R
Sbjct: 455 RITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRL 514
Query: 376 ERSEKKQPQV-------------IEGNNTYKSEK-------------------------- 396
E E QPQV I+ + T +
Sbjct: 515 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 574
Query: 397 --------------IQLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
I+L +N C + S R++++ +I +
Sbjct: 575 LLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI--- 631
Query: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 632 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 691
Query: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 692 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 748
Query: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
I K + L+K +K N E + KT Y +L L ENT L S+L K++ES+++LE E++
Sbjct: 749 IVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 808
Query: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
SY+ RL AA H ++ ++R+ +LA + T D ++ + L+ QLSK
Sbjct: 809 SYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKA 863
Query: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
+ K LK + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 864 ESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 922
Query: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 923 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 979
Query: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
EE NK L+NE +H KE QYE++KAE V++++
Sbjct: 980 EEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQ 1013
>gi|52856430 protein expressed in prostate, ovary, testis, and
placenta 15 [Homo sapiens]
Length = 581
Score = 247 bits (631), Expect = 3e-65
Identities = 175/554 (31%), Positives = 284/554 (51%), Gaps = 99/554 (17%)
Query: 19 DHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASG 78
D + Y +R +L K+H+AA G + + R D++ DKQ RTALHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 184
Query: 79 HVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV LL++R+CQ+++ D + RT LI+AV CQE+ C ++LLEHGA+ N++D YGNTALH
Sbjct: 185 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 244
Query: 139 YAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRL 198
YA+Y+E +A+ LL +G +IE+ +K TPLL + +K+++V+FL+K KA+ +A+DR
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 199 RXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHKKMI 258
TAL+LAV S IVN+LL+Q+++V +QD+ G+ A +YA+S
Sbjct: 305 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVS----------------- 347
Query: 259 LKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEKVSEPLRGPSHGKGN 318
S H +C + ++L ++++ PE+
Sbjct: 348 ----------------SHHHVICELLSDYKEKQMLKISSENSNPEQ-------------- 377
Query: 319 RIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERS 378
LK ++E E +K + +N Q + Q + + +++ E
Sbjct: 378 ---------------DLKLTSEEESQRLKVS---ENSQPEKMSQEPEINKDCDREVEEEI 419
Query: 379 EKKQPQVIEGNNTYKSEKIQLSENICHSTFSA-AADRLTQQRKIGKTYPQQFPKKLKEEH 437
+K + S + L EN+ + + D L QRK K QQFP EE+
Sbjct: 420 KK-----------HGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEY 468
Query: 438 DRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTP 497
+E+ L ++ + + E K+ KQ+E V EM K +
Sbjct: 469 ------HSDEQNDTQKQLSEEQNTGISQDEILTNKQ---KQIE--VAEKEMNSKLSL--- 514
Query: 498 NQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALE 557
+H++ +DL+ EN +L+ +IA+LR E+ K+ N +ENK L++I+ KE L
Sbjct: 515 -----SHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENKILEEIESVKE---KLL 566
Query: 558 KCIKLNEEMITKTA 571
K I+LNEE +TKT+
Sbjct: 567 KAIQLNEEALTKTS 580
>gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 475
Score = 245 bits (626), Expect = 1e-64
Identities = 155/403 (38%), Positives = 238/403 (59%), Gaps = 26/403 (6%)
Query: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 85 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 144
Query: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
++ KT N NQ +E +DL+ EN +++ +IA LR + T+KN NLEK KYLKD +
Sbjct: 145 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLDTDTIKNQNLEK--KYLKDFE 201
Query: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
I K + L+K +K N E + KT Y +L L ENT L S+L K++ES+++LE E++
Sbjct: 202 IVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 261
Query: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
SY RL AA H ++ ++R+ +LA + T D ++ + L+ QLSK
Sbjct: 262 SYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKA 316
Query: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
+ K LK + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 317 ESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 375
Query: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 376 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 432
Query: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRK 821
EE NK L+NE +H KE QYE++KAE VSIK++KYF K
Sbjct: 433 EEDNKMLVNELNHSKEKECQYEKEKAEREVSIKKNKYFSNFLK 475
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,683,649
Number of Sequences: 37866
Number of extensions: 1323236
Number of successful extensions: 14648
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 509
Number of HSP's successfully gapped in prelim test: 983
Number of HSP's that attempted gapping in prelim test: 6543
Number of HSP's gapped (non-prelim): 5099
length of query: 823
length of database: 18,247,518
effective HSP length: 111
effective length of query: 712
effective length of database: 14,044,392
effective search space: 9999607104
effective search space used: 9999607104
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.