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Search of human proteins with 239750365
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239750365 PREDICTED: TBC1 domain family, member 30 [Homo
sapiens]
(761 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239750365 PREDICTED: TBC1 domain family, member 30 [Homo sapi... 1543 0.0
gi|239755853 PREDICTED: TBC1 domain family, member 30 [Homo sapi... 1543 0.0
gi|239744669 PREDICTED: TBC1 domain family, member 30 [Homo sapi... 1543 0.0
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 109 8e-24
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 107 5e-23
gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 105 1e-22
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso... 105 1e-22
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso... 105 1e-22
gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 103 5e-22
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens] 99 1e-20
gi|156231067 TBC1 domain family, member 8 [Homo sapiens] 98 2e-20
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 94 5e-19
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 94 6e-19
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 90 7e-18
gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 78 3e-14
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 75 2e-13
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 75 2e-13
gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo... 74 5e-13
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 71 4e-12
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 71 4e-12
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 70 6e-12
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 70 6e-12
gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 70 6e-12
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 70 1e-11
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 65 2e-10
gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 65 2e-10
gi|34147456 TBC domain-containing protein kinase-like [Homo sapi... 60 1e-08
gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] 59 2e-08
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 59 2e-08
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 59 2e-08
>gi|239750365 PREDICTED: TBC1 domain family, member 30 [Homo
sapiens]
Length = 761
Score = 1543 bits (3996), Expect = 0.0
Identities = 761/761 (100%), Positives = 761/761 (100%)
Query: 1 MRQDKLTGSLRRGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFT 60
MRQDKLTGSLRRGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFT
Sbjct: 1 MRQDKLTGSLRRGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFT 60
Query: 61 LEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN 120
LEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN
Sbjct: 61 LEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN 120
Query: 121 ERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNI 180
ERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNI
Sbjct: 121 ERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNI 180
Query: 181 LAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ 240
LAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ
Sbjct: 181 LAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ 240
Query: 241 HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR 300
HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR
Sbjct: 241 HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR 300
Query: 301 VSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLA 360
VSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLA
Sbjct: 301 VSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLA 360
Query: 361 ELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP 420
ELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP
Sbjct: 361 ELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP 420
Query: 421 ELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQ 480
ELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQ
Sbjct: 421 ELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQ 480
Query: 481 YSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIH 540
YSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIH
Sbjct: 481 YSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIH 540
Query: 541 IPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTIGLIDEQNEASK 600
IPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTIGLIDEQNEASK
Sbjct: 541 IPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTIGLIDEQNEASK 600
Query: 601 TNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALE 660
TNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALE
Sbjct: 601 TNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALE 660
Query: 661 LNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRK 720
LNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRK
Sbjct: 661 LNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRK 720
Query: 721 SATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR 761
SATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR
Sbjct: 721 SATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR 761
>gi|239755853 PREDICTED: TBC1 domain family, member 30 [Homo
sapiens]
Length = 761
Score = 1543 bits (3995), Expect = 0.0
Identities = 760/761 (99%), Positives = 761/761 (100%)
Query: 1 MRQDKLTGSLRRGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFT 60
MRQDKLTGSLRRGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFT
Sbjct: 1 MRQDKLTGSLRRGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFT 60
Query: 61 LEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN 120
LEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN
Sbjct: 61 LEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN 120
Query: 121 ERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNI 180
ERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNI
Sbjct: 121 ERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNI 180
Query: 181 LAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ 240
LAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ
Sbjct: 181 LAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ 240
Query: 241 HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR 300
HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR
Sbjct: 241 HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR 300
Query: 301 VSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLA 360
VSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLA
Sbjct: 301 VSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLA 360
Query: 361 ELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP 420
ELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP
Sbjct: 361 ELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP 420
Query: 421 ELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQ 480
ELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQ
Sbjct: 421 ELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQ 480
Query: 481 YSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIH 540
YSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIH
Sbjct: 481 YSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIH 540
Query: 541 IPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTIGLIDEQNEASK 600
IPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDT+GLIDEQNEASK
Sbjct: 541 IPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASK 600
Query: 601 TNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALE 660
TNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALE
Sbjct: 601 TNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALE 660
Query: 661 LNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRK 720
LNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRK
Sbjct: 661 LNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRK 720
Query: 721 SATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR 761
SATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR
Sbjct: 721 SATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR 761
>gi|239744669 PREDICTED: TBC1 domain family, member 30 [Homo
sapiens]
Length = 761
Score = 1543 bits (3995), Expect = 0.0
Identities = 760/761 (99%), Positives = 761/761 (100%)
Query: 1 MRQDKLTGSLRRGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFT 60
MRQDKLTGSLRRGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFT
Sbjct: 1 MRQDKLTGSLRRGGRCLKRQGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFT 60
Query: 61 LEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN 120
LEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN
Sbjct: 61 LEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN 120
Query: 121 ERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNI 180
ERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNI
Sbjct: 121 ERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNI 180
Query: 181 LAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ 240
LAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ
Sbjct: 181 LAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ 240
Query: 241 HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR 300
HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR
Sbjct: 241 HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR 300
Query: 301 VSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLA 360
VSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLA
Sbjct: 301 VSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLA 360
Query: 361 ELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP 420
ELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP
Sbjct: 361 ELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP 420
Query: 421 ELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQ 480
ELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQ
Sbjct: 421 ELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQ 480
Query: 481 YSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIH 540
YSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIH
Sbjct: 481 YSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIH 540
Query: 541 IPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTIGLIDEQNEASK 600
IPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDT+GLIDEQNEASK
Sbjct: 541 IPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASK 600
Query: 601 TNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALE 660
TNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALE
Sbjct: 601 TNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALE 660
Query: 661 LNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRK 720
LNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRK
Sbjct: 661 LNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRK 720
Query: 721 SATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR 761
SATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR
Sbjct: 721 SATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR 761
>gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]
Length = 963
Score = 109 bits (273), Expect = 8e-24
Identities = 79/293 (26%), Positives = 137/293 (46%), Gaps = 31/293 (10%)
Query: 83 LSTGIPKEWRRKVWLTLADHYLHSIAIDWD----KTMRFTFNERSNPDDDSMGIQIVKDL 138
+ GIP E R KVW D + + + +T+ E+ NP + + +++ L
Sbjct: 659 IRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDLLRTL 718
Query: 139 HRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALK 198
S E Q L+ VLLA++ N +GYCQG N L A+ L +E + DA
Sbjct: 719 PNNKHYSCPTSEGIQK---LRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLE--QEDAFW 773
Query: 199 IMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYE 258
++ +++ +P Y+ L VD VFRDL+ KLP L H + Y+
Sbjct: 774 CLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQ------------YK 821
Query: 259 PPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCET 318
T + T WFL +F + + + KIWDS +EG ++I R +LA++ E+I +
Sbjct: 822 VDYT-LITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQD 880
Query: 319 ADEFYSTMGRLTQEMLENDLLQSHELMQTVY-SMAPFPFPQLAELREKYTYNI 370
+ + + T+ +L+ + +L+ + + PFP L ++R + Y++
Sbjct: 881 SMSIFKYLRYFTRTILD-----ARKLISISFGDLNPFP---LRQIRNRRAYHL 925
>gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]
Length = 914
Score = 107 bits (266), Expect = 5e-23
Identities = 72/257 (28%), Positives = 120/257 (46%), Gaps = 22/257 (8%)
Query: 83 LSTGIPKEWRRKVWLTLADHYLHSIAIDWD----KTMRFTFNERSNPDDDSMGIQIVKDL 138
+ GIP E R KVW D + + + +T+ E+ NP + + +++ L
Sbjct: 659 IRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDLLRTL 718
Query: 139 HRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALK 198
S E Q L+ VLLA++ N +GYCQG N L A+ L +E + DA
Sbjct: 719 PNNKHYSCPTSEGIQK---LRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLE--QEDAFW 773
Query: 199 IMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYE 258
++ +++ +P Y+ L VD VFRDL+ KLP L H + Y+
Sbjct: 774 CLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQ------------YK 821
Query: 259 PPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCET 318
T + T WFL +F + + + KIWDS +EG ++I R +LA++ E+I +
Sbjct: 822 VDYT-LITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQD 880
Query: 319 ADEFYSTMGRLTQEMLE 335
+ + + T+ +L+
Sbjct: 881 SMSIFKYLRYFTRTILD 897
>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
Length = 917
Score = 105 bits (263), Expect = 1e-22
Identities = 88/288 (30%), Positives = 135/288 (46%), Gaps = 45/288 (15%)
Query: 83 LSTGIPKEWRRKVWLTLAD---HYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLH 139
L G+P+E R +VW L +LH+ + R E QI DL+
Sbjct: 622 LRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHP------AARQIELDLN 675
Query: 140 RTGCSSY---CGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDA 196
RT ++ C + D+ L+RVLLA++ N T+GYCQG N LAA+ L V+E E A
Sbjct: 676 RTFPNNKHFTCPTSSFPDK--LRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLE-EEESA 732
Query: 197 LKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGG 256
++ +++ ++P Y+ N L A VD V +DLL KLP L HL G
Sbjct: 733 FWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHL------------GQ 780
Query: 257 YEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECC 316
+ L+ V T WFL +FA L + +L++WD+ +EG++ + L +
Sbjct: 781 HHVDLSLV-TFNWFLVVFADSLISNILLRVWDAFLYEGTKYNEKEILRL----------- 828
Query: 317 ETADEFYSTMGRLTQEMLENDLLQSHELMQTVYS-MAPFPFPQLAELR 363
+ E Y + T+ + S +LM ++ M PF QL +LR
Sbjct: 829 QNGLEIYQYLRFFTK-----TISNSRKLMNIAFNDMNPFRMKQLRQLR 871
>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
isoform b [Homo sapiens]
Length = 1233
Score = 105 bits (263), Expect = 1e-22
Identities = 75/255 (29%), Positives = 128/255 (50%), Gaps = 21/255 (8%)
Query: 74 YDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQ 133
Y K A + GIP+ R ++WL + + + E+S +
Sbjct: 496 YRTAKTRALVLKGIPESLRGELWLLFSGAWNEMVT---HPGYYAELVEKSTGKYSLATEE 552
Query: 134 IVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNE 193
I +DLHR+ + + E L+RVL AYA N T+GYCQ NI+ +++L + G+E
Sbjct: 553 IERDLHRS-MPEHPAFQNELGIAALRRVLTAYAFRNPTIGYCQAMNIVTSVLL--LYGSE 609
Query: 194 GDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKES 253
+A +++ L +++LP+ Y + AL VD +F +L R LP+LS+ + L
Sbjct: 610 EEAFWLLVALCERMLPDYYNTRVVGAL-VDQGIFEELTRDFLPQLSEKMQDLG------- 661
Query: 254 GGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQI 313
+ + ++ WFLTLF + +P ++ + I D F+EG ++IL+V+LA+ EQ+
Sbjct: 662 -------VISSISLSWFLTLFLSVMPFESAVVIVDCFFYEGIKVILQVALAVLDANMEQL 714
Query: 314 ECCETADEFYSTMGR 328
C E + +GR
Sbjct: 715 LGCSDEGEAMTMLGR 729
>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1250
Score = 105 bits (263), Expect = 1e-22
Identities = 75/255 (29%), Positives = 128/255 (50%), Gaps = 21/255 (8%)
Query: 74 YDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQ 133
Y K A + GIP+ R ++WL + + + E+S +
Sbjct: 496 YRTAKTRALVLKGIPESLRGELWLLFSGAWNEMVT---HPGYYAELVEKSTGKYSLATEE 552
Query: 134 IVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNE 193
I +DLHR+ + + E L+RVL AYA N T+GYCQ NI+ +++L + G+E
Sbjct: 553 IERDLHRS-MPEHPAFQNELGIAALRRVLTAYAFRNPTIGYCQAMNIVTSVLL--LYGSE 609
Query: 194 GDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKES 253
+A +++ L +++LP+ Y + AL VD +F +L R LP+LS+ + L
Sbjct: 610 EEAFWLLVALCERMLPDYYNTRVVGAL-VDQGIFEELTRDFLPQLSEKMQDLG------- 661
Query: 254 GGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQI 313
+ + ++ WFLTLF + +P ++ + I D F+EG ++IL+V+LA+ EQ+
Sbjct: 662 -------VISSISLSWFLTLFLSVMPFESAVVIVDCFFYEGIKVILQVALAVLDANMEQL 714
Query: 314 ECCETADEFYSTMGR 328
C E + +GR
Sbjct: 715 LGCSDEGEAMTMLGR 729
>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
Length = 749
Score = 103 bits (258), Expect = 5e-22
Identities = 78/258 (30%), Positives = 128/258 (49%), Gaps = 25/258 (9%)
Query: 86 GIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNE---RSNPDDDSMGIQIVKDLHRTG 142
GIP R ++W+ L+ A+ + ++ E S+ D+ QI KDL RT
Sbjct: 114 GIPHGMRPQLWMRLSG------ALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTM 167
Query: 143 CSSYCGQEAEQDRVV-LKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMI 201
S+ C V L+RVL A A +GYCQG ++AA +L +E E DA +M
Sbjct: 168 PSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLE--EEDAFWMMS 225
Query: 202 YLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEPPL 261
+I+ +LP SYF L + D V R L+ LP L D L + + E
Sbjct: 226 AIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRL----DKLLQEHDIE--------- 272
Query: 262 TNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADE 321
++ T+ WFLT FA+ + + +L+IWD F+EGS ++ +++L + E++ E +
Sbjct: 273 LSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSAS 332
Query: 322 FYSTMGRLTQEMLENDLL 339
++T+ + +M + +LL
Sbjct: 333 IFNTLSDIPSQMEDAELL 350
>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
Length = 336
Score = 99.0 bits (245), Expect = 1e-20
Identities = 76/282 (26%), Positives = 132/282 (46%), Gaps = 26/282 (9%)
Query: 86 GIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSS 145
G+P E R +VW+ L+ D+ + + + I DL+RT +
Sbjct: 68 GVPLEHRARVWMVLS-----GAQAQMDQNPGYYHQLLQGERNPRLEDAIRTDLNRTFPDN 122
Query: 146 YCGQEAEQDRV--VLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIYL 203
++ + L VLLAY N+ VGYCQG N +A ++ ++ NE ++ ++ L
Sbjct: 123 VKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLI-LITNNEEESFWLLDAL 181
Query: 204 IDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEPPLTN 263
+ ++LP+ Y+ + L D V +L+R KLP + ++ L L
Sbjct: 182 VGRILPD-YYSPAMLGLKTDQEVLGELVRAKLPAVGALMERLG-------------VLWT 227
Query: 264 VFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFY 323
+ +WF+ LF LP +TVL+IWD +F EGS+II RV+L + + E I + +
Sbjct: 228 LLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQELILEATSVPDIC 287
Query: 324 STMGRLTQEMLENDLLQSHELMQTVYS-MAPFPFPQLAELRE 364
++T+ +++ H MQ ++S +A+LRE
Sbjct: 288 DKFKQITKGSF---VMECHTFMQKIFSEPGSLSMATVAKLRE 326
>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
Length = 1140
Score = 98.2 bits (243), Expect = 2e-20
Identities = 67/250 (26%), Positives = 126/250 (50%), Gaps = 35/250 (14%)
Query: 83 LSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGI------QIVK 136
++ GIP+ R ++WL +D + N ++S+G +I +
Sbjct: 502 VAMGIPESLRGRLWLLFSDAVTDLASHP---------GYYGNLVEESLGKCCLVTEEIER 552
Query: 137 DLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDA 196
DLHR+ + + E L+RVL AYA N +GYCQ NIL +++L + E +A
Sbjct: 553 DLHRS-LPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLL--LYTKEEEA 609
Query: 197 LKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGG 256
+++ + +++LP+ YF + + VD +VF +L++ LPEL++H++ L A+
Sbjct: 610 FWLLVAVCERMLPD-YFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALAS------ 662
Query: 257 YEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECC 316
++ WFLTLF + +P ++ + + D F++G + I ++ LA+ E + C
Sbjct: 663 --------VSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDL--C 712
Query: 317 ETADEFYSTM 326
+ D+ + M
Sbjct: 713 SSKDDGQALM 722
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 94.0 bits (232), Expect = 5e-19
Identities = 69/255 (27%), Positives = 126/255 (49%), Gaps = 27/255 (10%)
Query: 86 GIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFN---ERSNPDDDSMGIQIVKDLHRTG 142
GIP+ R ++WL L+ AI+ T + E+S + +I +DLHR+
Sbjct: 515 GIPESMRGELWLLLSG------AINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRS- 567
Query: 143 CSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIY 202
+ + E L+RVL AYA N +GYCQ NI+ +++L + E +A +++
Sbjct: 568 LPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLL--LYAKEEEAFWLLVA 625
Query: 203 LIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEPPLT 262
L +++LP+ Y + AL VD VF +L R +P+L + L +
Sbjct: 626 LCERMLPDYYNTRVVGAL-VDQGVFEELARDYVPQLYDCMQDLG--------------VI 670
Query: 263 NVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEF 322
+ ++ WFLTLF + +P ++ + + D F+EG ++I +++LA+ +++ C+ E
Sbjct: 671 STISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEA 730
Query: 323 YSTMGRLTQEMLEND 337
+ +GR + D
Sbjct: 731 MTVLGRYLDSVTNKD 745
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1120
Score = 93.6 bits (231), Expect = 6e-19
Identities = 70/264 (26%), Positives = 131/264 (49%), Gaps = 45/264 (17%)
Query: 86 GIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPD------DDSMGI------Q 133
GIP+ R ++W+ L S A++ + +NPD + S+G +
Sbjct: 487 GIPETLRGELWM------LFSGAVN---------DMATNPDYYTEVVEQSLGTCNLATEE 531
Query: 134 IVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNE 193
I +DL R+ + +++ L+RVL AYA N +GYCQ NIL +++L + E
Sbjct: 532 IERDLRRS-LPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLL--LYAKE 588
Query: 194 GDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKES 253
+A +++ + +++LP+ YF + VD AVF +L+R LP+L++H+ + ++
Sbjct: 589 EEAFWLLVAVCERMLPD-YFNRRIIGALVDQAVFEELIRDHLPQLTEHMTDMTFFSS--- 644
Query: 254 GGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQI 313
++ WFLTLF + LP ++ + + D F++G + IL++ LAI +++
Sbjct: 645 -----------VSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKL 693
Query: 314 ECCETADEFYSTMGRLTQEMLEND 337
C+ E + + R + D
Sbjct: 694 LTCKDDAEAVTALNRFFDNVTNKD 717
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 90.1 bits (222), Expect = 7e-18
Identities = 86/294 (29%), Positives = 133/294 (45%), Gaps = 32/294 (10%)
Query: 78 KAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKD 137
K R GIP R K W L++ S + +F ER+ D + + I KD
Sbjct: 352 KVKLRCRKGIPSSLRAKAWQYLSN----SKELLEQNPGKFEELERAPGDPKWLDV-IEKD 406
Query: 138 LHRT----GCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNE 193
LHR + G +QD L R+L AY + GYCQ +AA++L M +
Sbjct: 407 LHRQFPFHEMFAARGGHGQQD---LYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQ 463
Query: 194 GDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKES 253
A ++ + DK LP Y+ L A+ +D +F LLR P +HL +
Sbjct: 464 --AFWCLVQICDKYLP-GYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQR------- 513
Query: 254 GGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWA-KLG-- 310
+P L + +WF+ +FA LP +VL++WD F EG +II RV+L + LG
Sbjct: 514 ---IDPVL---YMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSV 567
Query: 311 EQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLAELRE 364
E++ C+ E + L Q+ ++ D L HE+ + A A+L++
Sbjct: 568 EKLRSCQGMYETMEQLRNLPQQCMQEDFL-VHEVTNLPVTEALIERENAAQLKK 620
>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
Length = 446
Score = 78.2 bits (191), Expect = 3e-14
Identities = 63/223 (28%), Positives = 103/223 (46%), Gaps = 26/223 (11%)
Query: 86 GIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIV-KDLHRTGC- 143
GIP R + W L ++ K T+ E + D ++ + +DLHR
Sbjct: 92 GIPSALRARCWPLLCGAHV------CQKNSPGTYQELAEAPGDPQWMETIGRDLHRQFPL 145
Query: 144 -SSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIY 202
+ + + +L+ VL AY + GYCQ +AA++L + E A ++
Sbjct: 146 HEMFVSPQGHGQQGLLQ-VLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEE--AFWCLVQ 202
Query: 203 LIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEPPLT 262
+ + LP Y+ ++ A+ +D VF LLR LP + +HL + G P L
Sbjct: 203 ICEVYLP-GYYGPHMEAVRLDAEVFMALLRRLLPHVHKHLQQV----------GVGPLL- 250
Query: 263 NVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAI 305
+ +WFL LFA LP TVL++WD+ EG+ ++ RV L +
Sbjct: 251 --YLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTL 291
>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
[Homo sapiens]
Length = 1168
Score = 75.5 bits (184), Expect = 2e-13
Identities = 71/286 (24%), Positives = 129/286 (45%), Gaps = 40/286 (13%)
Query: 74 YDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDD------ 127
+D K + + G+P+ R ++W LA+ + ++ F + P D
Sbjct: 788 FDMEKMHSAVGQGVPRHHRGEIWKFLAEQF----------HLKHQFPSKQQPKDVPYKEL 837
Query: 128 ----DSMGIQIVKDLHRT-GCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILA 182
S I+ DL RT Y + ++ L +L AY+ ++ VGYCQG + +A
Sbjct: 838 LKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVA 897
Query: 183 ALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHL 242
++L M +E +A K++ +L+ + + ++ L + M LL +L HL
Sbjct: 898 GILLLHM--SEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHL 955
Query: 243 DTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVS 302
+ E G +++ WFLT+FA+ P V +++D +F +G+E+I +V+
Sbjct: 956 E------EHEIG-------PSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVA 1002
Query: 303 LAIWAK---LGEQIECCETADEFY-STMGRLTQEMLENDLLQSHEL 344
L++ L Q E ET +F ST+ L +E + Q E+
Sbjct: 1003 LSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEM 1048
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 75.1 bits (183), Expect = 2e-13
Identities = 77/277 (27%), Positives = 118/277 (42%), Gaps = 36/277 (12%)
Query: 82 RLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRT 141
R GIP R + W YL + + +P D I +DLHR
Sbjct: 107 RCQKGIPPSLRGRAW-----QYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQ 161
Query: 142 GCSSYC----GQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDAL 197
G +QD L RVL AY + GYCQ +AA++L M + A
Sbjct: 162 FPFHEMFVSRGGHGQQD---LFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQ--AF 216
Query: 198 KIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGY 257
++ + +K LP Y+ L A+ +D + LL+ P +HL +
Sbjct: 217 WCLVQICEKYLP-GYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQK----------I 265
Query: 258 EPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWA-KLG--EQIE 314
+P L + +WF+ F+ LP +VL++WD F EG +II RV L + LG E+++
Sbjct: 266 DPLL---YMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVK 322
Query: 315 CCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSM 351
C+ Y T+ RL L ++Q L+Q V +
Sbjct: 323 ACQGQ---YETIERL--RSLSPKIMQEAFLVQEVVEL 354
>gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo
sapiens]
Length = 815
Score = 73.9 bits (180), Expect = 5e-13
Identities = 59/224 (26%), Positives = 100/224 (44%), Gaps = 24/224 (10%)
Query: 83 LSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRT- 141
+ +G+P+ R +VW LA + + +D R+ + +S+ I +D+HRT
Sbjct: 535 VKSGVPEALRAEVWQLLAGCHDNQAMLD-----RYRILITKDSAQESV---ITRDIHRTF 586
Query: 142 GCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMI 201
Y + L ++ AY+ +++ +GYCQG + LAA++L M E A +++
Sbjct: 587 PAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMP--EEQAFCVLV 644
Query: 202 YLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEPPL 261
++ + NN L L++ +LP+L H L A+
Sbjct: 645 KIMYDYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAH----------- 693
Query: 262 TNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAI 305
++ QWFLTLF P V I D + EG II V+LA+
Sbjct: 694 --MYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALAL 735
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 70.9 bits (172), Expect = 4e-12
Identities = 60/242 (24%), Positives = 113/242 (46%), Gaps = 29/242 (11%)
Query: 68 NGFQQWYDALKAVAR--LSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNP 125
N +++W + + + + GIP +R VW L + + + ++ S+P
Sbjct: 95 NEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKM-----SSP 149
Query: 126 DDDSMGIQIVKDLHRTGCSS--YCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAA 183
+ I +D+ RT + GQ++ + VL V+ AY+ ++ VGYCQG +
Sbjct: 150 CEKL----IRRDIARTYPEHEFFKGQDS-LGQEVLFNVMKAYSLVDREVGYCQGSAFIVG 204
Query: 184 LILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLD 243
L+L M+ E +A + + L+ + F ++ L + + F +L+ +LP+L+ H
Sbjct: 205 LLL--MQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFR 262
Query: 244 TLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSL 303
+ + T+++ WFLTLF T P +++D +EG EI+ RV L
Sbjct: 263 S-------------QSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGL 309
Query: 304 AI 305
A+
Sbjct: 310 AL 311
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 70.9 bits (172), Expect = 4e-12
Identities = 60/242 (24%), Positives = 113/242 (46%), Gaps = 29/242 (11%)
Query: 68 NGFQQWYDALKAVAR--LSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNP 125
N +++W + + + + GIP +R VW L + + + ++ S+P
Sbjct: 95 NEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKM-----SSP 149
Query: 126 DDDSMGIQIVKDLHRTGCSS--YCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAA 183
+ I +D+ RT + GQ++ + VL V+ AY+ ++ VGYCQG +
Sbjct: 150 CEKL----IRRDIARTYPEHEFFKGQDS-LGQEVLFNVMKAYSLVDREVGYCQGSAFIVG 204
Query: 184 LILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLD 243
L+L M+ E +A + + L+ + F ++ L + + F +L+ +LP+L+ H
Sbjct: 205 LLL--MQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFR 262
Query: 244 TLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSL 303
+ + T+++ WFLTLF T P +++D +EG EI+ RV L
Sbjct: 263 S-------------QSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGL 309
Query: 304 AI 305
A+
Sbjct: 310 AL 311
>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
Length = 828
Score = 70.5 bits (171), Expect = 6e-12
Identities = 69/245 (28%), Positives = 106/245 (43%), Gaps = 32/245 (13%)
Query: 69 GFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDD 128
G++++ + K R+ GIP + R +VW L + I ++T +
Sbjct: 83 GWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLE-----IPKMKEETRDLYSKLKHRARGC 137
Query: 129 SMGI-QIVKDLHRTGCSSYCGQEAEQDRVVLKR-----VLLAYARWNKTVGYCQGFNILA 182
S I QI D++RT + +DR +K+ VL AY+ +N VGYCQG + +
Sbjct: 138 SPDIRQIDLDVNRT----FRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQIT 193
Query: 183 ALILEVMEGNEGDALKIMIYLID--KVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ 240
AL+L M NE DA ++ L K +FV L +L L +L Q
Sbjct: 194 ALLLMYM--NEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQ 251
Query: 241 HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR 300
HLD+ + T+ +TM+WF F P L+IWD FEG ++
Sbjct: 252 HLDS-------------QEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTA 298
Query: 301 VSLAI 305
+S I
Sbjct: 299 MSYTI 303
Score = 33.5 bits (75), Expect = 0.76
Identities = 42/164 (25%), Positives = 64/164 (39%), Gaps = 36/164 (21%)
Query: 623 SSPEGSTRRTIEGQSPEP-------VFGDADVDVSAVQAKLGAL---------------- 659
S+ E + + T+EG+ V G A+V VS V+ K+ AL
Sbjct: 494 SATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDN 553
Query: 660 ----ELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKT-PIFSPFPS 714
EL+ + E R + RH PPS + + +S + SN T + P +
Sbjct: 554 VPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHA 613
Query: 715 VKPLRKSATARNLGLYGPTERTPTV-------HFPQMSRSFSKP 751
P + AR L + P+ P V HFP + SF+ P
Sbjct: 614 RYPSQLDGEARGLA-HPPSYSNPPVYHGNSPKHFPTANSSFASP 656
>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
Length = 845
Score = 70.5 bits (171), Expect = 6e-12
Identities = 69/245 (28%), Positives = 106/245 (43%), Gaps = 32/245 (13%)
Query: 69 GFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDD 128
G++++ + K R+ GIP + R +VW L + I ++T +
Sbjct: 100 GWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLE-----IPKMKEETRDLYSKLKHRARGC 154
Query: 129 SMGI-QIVKDLHRTGCSSYCGQEAEQDRVVLKR-----VLLAYARWNKTVGYCQGFNILA 182
S I QI D++RT + +DR +K+ VL AY+ +N VGYCQG + +
Sbjct: 155 SPDIRQIDLDVNRT----FRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQIT 210
Query: 183 ALILEVMEGNEGDALKIMIYLID--KVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQ 240
AL+L M NE DA ++ L K +FV L +L L +L Q
Sbjct: 211 ALLLMYM--NEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQ 268
Query: 241 HLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILR 300
HLD+ + T+ +TM+WF F P L+IWD FEG ++
Sbjct: 269 HLDS-------------QEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTA 315
Query: 301 VSLAI 305
+S I
Sbjct: 316 MSYTI 320
Score = 33.5 bits (75), Expect = 0.76
Identities = 42/164 (25%), Positives = 64/164 (39%), Gaps = 36/164 (21%)
Query: 623 SSPEGSTRRTIEGQSPEP-------VFGDADVDVSAVQAKLGAL---------------- 659
S+ E + + T+EG+ V G A+V VS V+ K+ AL
Sbjct: 511 SATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDN 570
Query: 660 ----ELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKT-PIFSPFPS 714
EL+ + E R + RH PPS + + +S + SN T + P +
Sbjct: 571 VPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHA 630
Query: 715 VKPLRKSATARNLGLYGPTERTPTV-------HFPQMSRSFSKP 751
P + AR L + P+ P V HFP + SF+ P
Sbjct: 631 RYPSQLDGEARGLA-HPPSYSNPPVYHGNSPKHFPTANSSFASP 673
>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
Length = 1298
Score = 70.5 bits (171), Expect = 6e-12
Identities = 66/267 (24%), Positives = 117/267 (43%), Gaps = 36/267 (13%)
Query: 83 LSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDS----------MGI 132
L G+PK R ++W LA Y +R + P D S
Sbjct: 915 LKEGVPKSRRGEIWQFLALQY----------RLRHRLPNKQQPPDISYKELLKQLTAQQH 964
Query: 133 QIVKDLHRT-GCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEG 191
I+ DL RT Y + ++ L +L AY+ +K VGYCQG + +A ++L M
Sbjct: 965 AILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHM-- 1022
Query: 192 NEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANK 251
+E A +++ +L+ + + ++ +L + M LL +L HL+ N+
Sbjct: 1023 SEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEE-----NE 1077
Query: 252 ESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGE 311
S Y P WFLTLFA+ V +++D +F +G+E+I +V+L++ +
Sbjct: 1078 ISPSLYAAP--------WFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLSSQET 1129
Query: 312 QIECCETADEFYSTMGRLTQEMLENDL 338
I CE+ + + +M +++
Sbjct: 1130 LIMECESFENIVEFLKNTLPDMNTSEM 1156
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 69.7 bits (169), Expect = 1e-11
Identities = 62/240 (25%), Positives = 104/240 (43%), Gaps = 30/240 (12%)
Query: 72 QWYDALKAVAR-----LSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPD 126
+W D K + + GIP +R VW L I + + ++ T +P
Sbjct: 144 EWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMT-----SPC 198
Query: 127 DDSMGIQIVKDLHRTGCSSYCGQEAEQ-DRVVLKRVLLAYARWNKTVGYCQGFNILAALI 185
+ I +D+ RT +E + + VL V+ AY+ ++ VGYCQG + L+
Sbjct: 199 EKL----IRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLL 254
Query: 186 LEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTL 245
L M+ E +A + + L+ F ++ L + M F +++ LPEL H +
Sbjct: 255 L--MQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQS- 311
Query: 246 QRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAI 305
+ T+++ WFLT+F T P +I+D EG EI+ RV LA+
Sbjct: 312 ------------QSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLAL 359
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 65.1 bits (157), Expect = 2e-10
Identities = 56/226 (24%), Positives = 94/226 (41%), Gaps = 34/226 (15%)
Query: 86 GIPKEWRRKVWLTLA-----DHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHR 140
G+P+ R +VW LA DH + I + +P D + I +D++R
Sbjct: 566 GVPEALRGEVWQLLAGCHNNDHLVEKYRI---------LITKESPQDSA----ITRDINR 612
Query: 141 T-GCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKI 199
T Y + L ++ AY+ +++ +GYCQG + LAA++L M E A +
Sbjct: 613 TFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMP--EEQAFSV 670
Query: 200 MIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEP 259
++ ++ F N L L++ +P+L H + A+
Sbjct: 671 LVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAH--------- 721
Query: 260 PLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAI 305
++ QWFLTLF P V I D + EG +I V+L +
Sbjct: 722 ----MYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGL 763
>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
Length = 775
Score = 65.1 bits (157), Expect = 2e-10
Identities = 57/235 (24%), Positives = 97/235 (41%), Gaps = 30/235 (12%)
Query: 86 GIPKEWRRKVWLTLADHYL------HSIAIDWDKTMRFTFNERSNPDDDS--------MG 131
G+P R KVW + L + I + K +F+E S+ +D
Sbjct: 484 GLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREAS 543
Query: 132 IQIVK-DLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVME 190
++++K D+ RT S Y Q+ VL +L AY + VGY QG + +AA+++ +E
Sbjct: 544 LELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLE 603
Query: 191 GNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTAN 250
E DA L++K ++F + + A F L +L H + T +
Sbjct: 604 --EADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPD 661
Query: 251 KESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAI 305
++ + W TL++ LP ++WD +G E + R L I
Sbjct: 662 -------------IYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGI 703
>gi|34147456 TBC domain-containing protein kinase-like [Homo
sapiens]
Length = 830
Score = 59.7 bits (143), Expect = 1e-08
Identities = 41/155 (26%), Positives = 69/155 (44%), Gaps = 13/155 (8%)
Query: 159 KRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLR 218
+RVL A+ + + Y QG + L A L + NE A M I K L + +N
Sbjct: 466 RRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSH 525
Query: 219 ALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCL 278
+ + VF ++ PELS HL+ + G+ P L + + WFLT+F
Sbjct: 526 VIQEYLTVFSQMIAFHDPELSNHLNEI----------GFIPDL---YAIPWFLTMFTHVF 572
Query: 279 PNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQI 313
P + +WD++ S + +AI +L +++
Sbjct: 573 PLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRL 607
>gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]
Length = 413
Score = 58.5 bits (140), Expect = 2e-08
Identities = 66/278 (23%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 86 GIPKEWRRKVW-LTLAD-----HYLHSIAIDWDK----TMRFTFNERSNPD------DDS 129
GIP R KVW L + + H L I + K ++ +E N D D
Sbjct: 121 GIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADRE 180
Query: 130 MGIQIVK-DLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEV 188
++++K D+ RT + Q+ +L +L AY + VGY QG + +AA++ +
Sbjct: 181 ASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVL--I 238
Query: 189 MEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRT 248
+ + DA L++K ++F + + A F LP+L H T
Sbjct: 239 LNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLT 298
Query: 249 ANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAK 308
+ ++ + W TL++ LP +IWD +G E + R +L I K
Sbjct: 299 PD-------------IYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGI-LK 344
Query: 309 LGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQ 346
L E I + RL +++ +L S +Q
Sbjct: 345 LFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQ 382
>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 58.5 bits (140), Expect = 2e-08
Identities = 66/278 (23%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 86 GIPKEWRRKVW-LTLAD-----HYLHSIAIDWDK----TMRFTFNERSNPD------DDS 129
GIP R KVW L + + H L I + K ++ +E N D D
Sbjct: 401 GIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADRE 460
Query: 130 MGIQIVK-DLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEV 188
++++K D+ RT + Q+ +L +L AY + VGY QG + +AA++ +
Sbjct: 461 ASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVL--I 518
Query: 189 MEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRT 248
+ + DA L++K ++F + + A F LP+L H T
Sbjct: 519 LNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLT 578
Query: 249 ANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAK 308
+ ++ + W TL++ LP +IWD +G E + R +L I K
Sbjct: 579 PD-------------IYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGI-LK 624
Query: 309 LGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQ 346
L E I + RL +++ +L S +Q
Sbjct: 625 LFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQ 662
>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 58.5 bits (140), Expect = 2e-08
Identities = 66/278 (23%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 86 GIPKEWRRKVW-LTLAD-----HYLHSIAIDWDK----TMRFTFNERSNPD------DDS 129
GIP R KVW L + + H L I + K ++ +E N D D
Sbjct: 401 GIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADRE 460
Query: 130 MGIQIVK-DLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEV 188
++++K D+ RT + Q+ +L +L AY + VGY QG + +AA++ +
Sbjct: 461 ASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVL--I 518
Query: 189 MEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRT 248
+ + DA L++K ++F + + A F LP+L H T
Sbjct: 519 LNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLT 578
Query: 249 ANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAK 308
+ ++ + W TL++ LP +IWD +G E + R +L I K
Sbjct: 579 PD-------------IYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGI-LK 624
Query: 309 LGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQ 346
L E I + RL +++ +L S +Q
Sbjct: 625 LFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQ 662
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,443,424
Number of Sequences: 37866
Number of extensions: 1533465
Number of successful extensions: 6015
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 5767
Number of HSP's gapped (non-prelim): 242
length of query: 761
length of database: 18,247,518
effective HSP length: 110
effective length of query: 651
effective length of database: 14,082,258
effective search space: 9167549958
effective search space used: 9167549958
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.