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Search of human proteins with 117676403
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117676403 HIV-1 rev binding protein 2 [Homo sapiens]
(381 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117676403 HIV-1 rev binding protein 2 [Homo sapiens] 752 0.0
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 48 1e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 48 1e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 47 3e-05
gi|88759339 aster-associated protein [Homo sapiens] 45 1e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 44 2e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 44 2e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 44 2e-04
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 43 4e-04
gi|11225260 DNA topoisomerase I [Homo sapiens] 42 7e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 42 0.001
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 42 0.001
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 42 0.001
gi|221219020 NYD-SP11 protein [Homo sapiens] 42 0.001
gi|10047140 partner of NOB1 [Homo sapiens] 41 0.002
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 40 0.005
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 40 0.005
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 40 0.005
gi|104526627 triadin [Homo sapiens] 39 0.006
gi|169183877 PREDICTED: similar to hCG1742476 [Homo sapiens] 39 0.008
gi|169179771 PREDICTED: similar to hCG1742476 [Homo sapiens] 39 0.008
gi|239743692 PREDICTED: hypothetical protein LOC402360 [Homo sap... 39 0.008
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 39 0.008
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 39 0.008
gi|45505178 cancer antigen 1 [Homo sapiens] 39 0.010
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens] 39 0.010
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap... 39 0.010
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 38 0.017
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 37 0.023
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 37 0.030
>gi|117676403 HIV-1 rev binding protein 2 [Homo sapiens]
Length = 381
Score = 752 bits (1942), Expect = 0.0
Identities = 381/381 (100%), Positives = 381/381 (100%)
Query: 1 MASPSLERPEKGAGKSEFRNQKPKPENQDESELLTVPDGWKEPAFSKEDNPRGLLEESSF 60
MASPSLERPEKGAGKSEFRNQKPKPENQDESELLTVPDGWKEPAFSKEDNPRGLLEESSF
Sbjct: 1 MASPSLERPEKGAGKSEFRNQKPKPENQDESELLTVPDGWKEPAFSKEDNPRGLLEESSF 60
Query: 61 ATLFPKYREAYLKECWPLVQKALNEHHVNATLDLIEGSMTVCTTKKTFDPYIIIRARDLI 120
ATLFPKYREAYLKECWPLVQKALNEHHVNATLDLIEGSMTVCTTKKTFDPYIIIRARDLI
Sbjct: 61 ATLFPKYREAYLKECWPLVQKALNEHHVNATLDLIEGSMTVCTTKKTFDPYIIIRARDLI 120
Query: 121 KLLARSVSFEQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTN 180
KLLARSVSFEQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTN
Sbjct: 121 KLLARSVSFEQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTN 180
Query: 181 CYIMVQGNTVSAIGPFSGLKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWE 240
CYIMVQGNTVSAIGPFSGLKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWE
Sbjct: 181 CYIMVQGNTVSAIGPFSGLKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWE 240
Query: 241 RFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKME 300
RFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKME
Sbjct: 241 RFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKME 300
Query: 301 AIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGA 360
AIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGA
Sbjct: 301 AIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGA 360
Query: 361 LTAEEIALKMEADEKKKKKKK 381
LTAEEIALKMEADEKKKKKKK
Sbjct: 361 LTAEEIALKMEADEKKKKKKK 381
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 48.1 bits (113), Expect = 1e-05
Identities = 39/141 (27%), Positives = 69/141 (48%), Gaps = 15/141 (10%)
Query: 243 LPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAI 302
+ F +N R +PK V+KE E+ KE +A Q +RQK+E
Sbjct: 516 MKSFIKRNTPLRMDPKCSFVEKERQRL-----ENLRRKE--------EAEQLRRQKVEED 562
Query: 303 KAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALT 362
K ++ E + ++EER + + +E+ +E + + A I EK +KAK ++L
Sbjct: 563 KRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEK 622
Query: 363 AEE--IALKMEADEKKKKKKK 381
A++ A KME E ++K+++
Sbjct: 623 AKKKAAAKKMEEVEARRKQEE 643
Score = 43.1 bits (100), Expect = 4e-04
Identities = 48/243 (19%), Positives = 110/243 (45%), Gaps = 22/243 (9%)
Query: 142 CDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTNCYIMVQGNTVSAIGPFSGLKE 201
C K+ +R V+R Q L+ P + ++ ++ NT + P E
Sbjct: 483 CPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSF------IKRNTPLRMDPKCSFVE 536
Query: 202 VRKVVLDTMKNIHPIYNIKSLMI---KRELAKDSELRSQSWERFLPQFKHKNVNKRKEPK 258
+ L+ ++ ++ + KR ++ +L+ + R + Q + + V + KE K
Sbjct: 537 KERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER-VEQMKEEK 595
Query: 259 KKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERN 318
KK +++++ +QID++ + A +K ++K A K ++ EA K++EE
Sbjct: 596 KKQIEQKF---------AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 646
Query: 319 KAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKK 378
+ +E+ + +E + K + +E+++KA K A E+ + E E++++
Sbjct: 647 RLRWLQQEEEERRHQELLQKKKEEE---QERLRKAAEAKRLAEQREQERREQERREQERR 703
Query: 379 KKK 381
+++
Sbjct: 704 EQE 706
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 48.1 bits (113), Expect = 1e-05
Identities = 37/126 (29%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Query: 260 KTVKKEYTPF--PPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEER 317
K+ K TP P + E Q + L E +A Q +RQK+E K ++ E + ++EER
Sbjct: 517 KSFIKRNTPLRMDPKEKERQRLENLRRKE---EAEQLRRQKVEEDKRRRLEEVKLKREER 573
Query: 318 NKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEE--IALKMEADEK 375
+ + +E+ +E + + A I EK +KAK ++L A++ A KME E
Sbjct: 574 LRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA 633
Query: 376 KKKKKK 381
++K+++
Sbjct: 634 RRKQEE 639
Score = 41.6 bits (96), Expect = 0.001
Identities = 49/243 (20%), Positives = 111/243 (45%), Gaps = 26/243 (10%)
Query: 142 CDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTNCYIMVQGNTVSAIGPFSGLKE 201
C K+ +R V+R Q L+ P + ++ ++ NT + P KE
Sbjct: 483 CPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSF------IKRNTPLRMDP----KE 532
Query: 202 VRKVVLDTMKNIHPIYNIKSLMI---KRELAKDSELRSQSWERFLPQFKHKNVNKRKEPK 258
+ L+ ++ ++ + KR ++ +L+ + R + Q + + V + KE K
Sbjct: 533 KERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER-VEQMKEEK 591
Query: 259 KKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERN 318
KK +++++ +QID++ + A +K ++K A K ++ EA K++EE
Sbjct: 592 KKQIEQKF---------AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 642
Query: 319 KAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKK 378
+ +E+ + +E + K + +E+++KA K A E+ + E E++++
Sbjct: 643 RLRWLQQEEEERRHQELLQKKKEEE---QERLRKAAEAKRLAEQREQERREQERREQERR 699
Query: 379 KKK 381
+++
Sbjct: 700 EQE 702
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 11/161 (6%)
Query: 225 KRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELAS 284
++E+ K E++S E PQ K KEP KK +++ P + + KE A
Sbjct: 811 EKEIPKKEEVKSPVKEEEKPQEV-----KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP 865
Query: 285 GEYFLK--ANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPI-VKPKE-ASTETK 340
+ K +KK +E K + EA + E++ K P KE P V+ KE A + K
Sbjct: 866 KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK 925
Query: 341 IDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
+VA K++ AK K+ ++ A + D K++K KK
Sbjct: 926 TEVA--KKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKK 964
Score = 36.6 bits (83), Expect = 0.039
Identities = 40/151 (26%), Positives = 60/151 (39%), Gaps = 21/151 (13%)
Query: 249 KNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAE 308
K K K P K+ K +P PE ++ S E A ++ R + K
Sbjct: 731 KTPEKAKSPVKEEAK---SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787
Query: 309 AISKRQEERNKAFIPPK------EKPIVKPKEAST----ETKIDVASIKEKVKKAKNKKL 358
+ + + KA P K EK I K +E + E K +KE KKA+ +K
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 359 GAL--------TAEEIALKMEADEKKKKKKK 381
A + +E A K EA + K ++KK
Sbjct: 848 PATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878
Score = 34.7 bits (78), Expect = 0.15
Identities = 42/139 (30%), Positives = 62/139 (44%), Gaps = 17/139 (12%)
Query: 255 KEPKKKTVKKEYTPFP----PPQPESQIDKELASGEYF-------LKANQKKRQKMEAIK 303
K P+ KT KE P P + +S + +E+ S E KA +K+ K E +K
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 304 AKQAEAISKRQEERNKAFIPPKEKPIVK-PKEASTETKIDVASIKEKVKKAKNKKLGALT 362
+ E K QE + K PPK+ K P TE K D S KE+ K + K
Sbjct: 822 SPVKEE-EKPQEVKVKE--PPKKAEEEKAPATPKTEEKKD--SKKEEAPKKEAPKPKVEE 876
Query: 363 AEEIALKMEADEKKKKKKK 381
+E A++ + K + KK+
Sbjct: 877 KKEPAVEKPKESKVEAKKE 895
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 44.7 bits (104), Expect = 1e-04
Identities = 44/190 (23%), Positives = 81/190 (42%), Gaps = 28/190 (14%)
Query: 213 IHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPP 272
+H ++ IK + + ++ + ++ E L F+ K KE KK KK
Sbjct: 440 LHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKNKK 499
Query: 273 QPESQIDKELASG------------EYFLKANQKKRQKMEAIKAKQAEAISKRQE----- 315
+ E + EY + N+K+R+ A K K+ E ++++++
Sbjct: 500 KTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTA 559
Query: 316 -----ERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKM 370
E+ +AF KEK + K + ++ A K+K K+A N+ L +E K
Sbjct: 560 VEKWNEKKEAFFKQKEKEKINEKR---KEELKRAEKKDKDKQAINEYEKWLENKE---KQ 613
Query: 371 EADEKKKKKK 380
E E+K+KK+
Sbjct: 614 ERIERKQKKR 623
Score = 34.7 bits (78), Expect = 0.15
Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 10/143 (6%)
Query: 249 KNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAE 308
KNV + + K ++ E Q ++ +E + KA ++K K A K + E
Sbjct: 436 KNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEE 495
Query: 309 AISKRQEERN--------KAFIPPKEKPIVKPKEASTETKIDVASIKEKVKK--AKNKKL 358
K+ EE N +AF KEK + KE + + + + K+K ++ A+ KK
Sbjct: 496 KNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKD 555
Query: 359 GALTAEEIALKMEADEKKKKKKK 381
E+ K EA K+K+K+K
Sbjct: 556 NLTAVEKWNEKKEAFFKQKEKEK 578
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 43.9 bits (102), Expect = 2e-04
Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 18/157 (11%)
Query: 225 KRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELAS 284
KRE K+ E + + E+ + + K KRK+ KKK +K+ + E + KE
Sbjct: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ-----RGRRERKKKKERKE 122
Query: 285 GEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVA 344
E K +++++K K ++ E KR++ER K +E+ K K+ E K
Sbjct: 123 RERENKQRRERKRKKRRKKKRRKE--RKREKERGK-----RERKRKKRKKEEREKK---- 171
Query: 345 SIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
+E+ +K + K+ E + + + +KKK++K
Sbjct: 172 --RERNRKERKKERERKERRERKKERKKERRKKKERK 206
Score = 33.5 bits (75), Expect = 0.33
Identities = 34/163 (20%), Positives = 72/163 (44%), Gaps = 22/163 (13%)
Query: 219 IKSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQI 278
+K++ + + ++EL+ S + ++KE +++ +K E +
Sbjct: 2 VKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKR---------EREK 52
Query: 279 DKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTE 338
+++ G K +KKR+K E K ++ ++++ER K +EK K K+ +
Sbjct: 53 ERKRERG----KKEKKKRKKRERGKERE-----RKRKEREKQRKERREKERRKRKKEKKK 103
Query: 339 TKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
+ +E+ KK + K+ E + E KK++KKK
Sbjct: 104 RERKQRGRRERKKKKERKE----RERENKQRRERKRKKRRKKK 142
Score = 32.0 bits (71), Expect = 0.95
Identities = 33/157 (21%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
Query: 225 KRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELAS 284
K ++ R + ER + K K KRK+ ++ ++ Q + + +KE
Sbjct: 38 KERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKRKEREKQRKERREKERRK 96
Query: 285 GEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVA 344
K +KKR++ + + ++ + +++ ER +++ + K+ E K +
Sbjct: 97 ----RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Query: 345 SIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
K + K+ K KK EE K E + K++KK++
Sbjct: 153 RGKRERKRKKRKK------EEREKKRERNRKERKKER 183
Score = 29.3 bits (64), Expect = 6.2
Identities = 25/117 (21%), Positives = 52/117 (44%), Gaps = 8/117 (6%)
Query: 225 KRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELAS 284
+RE K E + + E K + KRK+ +KK +KE + K+
Sbjct: 111 RRERKKKKERKEREREN-----KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK 165
Query: 285 GEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKI 341
E + +++R + E K ++ + +R++ER K KE+ + + T++++
Sbjct: 166 EE---REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/124 (26%), Positives = 62/124 (50%), Gaps = 6/124 (4%)
Query: 258 KKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEER 317
KKK KK+ T E++ ++E G+ K +K+++K + K K+ E +++EE
Sbjct: 1 KKKKKKKKETEETEETEETE-EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59
Query: 318 NKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKK 377
K K+K + +E E + + +EK + + KK ++ K E +EKKK
Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK-----KKKRRRKEEEEEKKK 114
Query: 378 KKKK 381
K+++
Sbjct: 115 KRRR 118
Score = 42.7 bits (99), Expect = 5e-04
Identities = 33/129 (25%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Query: 253 KRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISK 312
K+K+ KK+T + E T + E + +KE G+ K +K+++K + K K+ E +
Sbjct: 2 KKKKKKKETEETEETE----ETEEEEEKE---GKRKEKRKEKRKEKEKKKKTKETEKRKE 54
Query: 313 RQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEA 372
++EE K K+K + +E E + + +EK + + KK +E + +
Sbjct: 55 KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Query: 373 DEKKKKKKK 381
++K KKK
Sbjct: 115 KRRRKTKKK 123
Score = 37.0 bits (84), Expect = 0.030
Identities = 35/133 (26%), Positives = 63/133 (47%), Gaps = 13/133 (9%)
Query: 225 KRELAKDSELRSQSWERFLPQFKH-KNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELA 283
K++ K++E ++ E + K K KRKE +K+ KK+ T E++ KE
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKT------KETEKRKEKE 56
Query: 284 SGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDV 343
E K +KK+++ E + ++ E +++EE + K+K + KE E K
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK--- 113
Query: 344 ASIKEKVKKAKNK 356
K++ +K K K
Sbjct: 114 ---KKRRRKTKKK 123
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/140 (29%), Positives = 65/140 (46%), Gaps = 11/140 (7%)
Query: 253 KRKEPKKKTVKKEYTPFPPPQPESQID--KELASGEYFLKANQKKRQKMEAIKAKQAEAI 310
K K K+KTVKKE P + E + KE+A E ++++ K E +K + + I
Sbjct: 629 KPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEI 688
Query: 311 SKRQEERNKAF----IPPKEKPIVKPKEASTETKIDVASIKEKVKK-AKNKKLGALTAEE 365
K +++ K PPKE KE E K + K+++KK K+ K + E
Sbjct: 689 KKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSE 748
Query: 366 ----IALKMEADEKKKKKKK 381
ALK + +K++ KK
Sbjct: 749 AKKPAALKPKVPKKEESVKK 768
Score = 40.4 bits (93), Expect = 0.003
Identities = 42/129 (32%), Positives = 58/129 (44%), Gaps = 13/129 (10%)
Query: 249 KNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQ-- 306
K +KE KK VKKE +P+ ++ KE E +K KK +K E K ++
Sbjct: 671 KEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKE--VKKEVKKEEKKEVKKEEKEP 728
Query: 307 AEAISKRQEERNKAFIPPKE-------KPIVKPKEASTETKIDVASIKEKVK-KAKNKKL 358
+ I K ++ K+ P E KP V KE S + K VA+ K K K K K K
Sbjct: 729 KKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVK-KDSVAAGKPKEKGKIKVIKK 787
Query: 359 GALTAEEIA 367
AE +A
Sbjct: 788 EGKAAEAVA 796
Score = 34.7 bits (78), Expect = 0.15
Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 2/137 (1%)
Query: 247 KHKNVNKRKEPKKKTVKKEYTPFPPPQPE--SQIDKELASGEYFLKANQKKRQKMEAIKA 304
K K + K+ +P K K T P E S + E+A + + ++K +
Sbjct: 583 KEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKET 642
Query: 305 KQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAE 364
K K ++E+ K + KE KE + + +K+++KK + K+ +
Sbjct: 643 KVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKK 702
Query: 365 EIALKMEADEKKKKKKK 381
E K E KK++KK
Sbjct: 703 ETPPKEVKKEVKKEEKK 719
Score = 33.9 bits (76), Expect = 0.25
Identities = 37/155 (23%), Positives = 72/155 (46%), Gaps = 27/155 (17%)
Query: 230 KDSELRSQSWERFLPQFKHKNVNKRKEP---KKKTVKKEYTPFPPPQPESQIDKELASGE 286
KD +++++ P K V ++EP K + +K+ T P + + K+ E
Sbjct: 590 KDKPIKTET----KPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKK----E 641
Query: 287 YFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASI 346
+K KK +K K + ++K+++ K I +EKP K +E E K ++
Sbjct: 642 TKVKPEDKKEEK-----EKPKKEVAKKED---KTPIKKEEKP--KKEEVKKEVKKEIKKE 691
Query: 347 KEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
++K K + KK E +++ + KK++KK+
Sbjct: 692 EKKEPKKEVKK------ETPPKEVKKEVKKEEKKE 720
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 43.1 bits (100), Expect = 4e-04
Identities = 36/161 (22%), Positives = 74/161 (45%), Gaps = 12/161 (7%)
Query: 226 RELAKDSELRSQSWERFLPQFKHKNVN-----KRKEPKKKTVKKEYTPFPPPQPESQIDK 280
+ LA+ E +++W++ L + + K ++ +K +KK KK+ S
Sbjct: 56 KALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSS 115
Query: 281 ELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETK 340
+ E K K+R+K + K +++ + E +K + K+K + TE +
Sbjct: 116 SSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKK-----SKDETEKE 170
Query: 341 IDVASIKEKVKKA--KNKKLGALTAEEIALKMEADEKKKKK 379
DV S+ +K KK+ +K L + ++ E + + KKK++
Sbjct: 171 KDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRR 211
Score = 30.8 bits (68), Expect = 2.1
Identities = 23/105 (21%), Positives = 46/105 (43%), Gaps = 5/105 (4%)
Query: 220 KSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQID 279
K+ K + E S+S E + K K+ ++++ + KK +P +P S
Sbjct: 135 KNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSES 194
Query: 280 KELASGEYFLKANQKKR-----QKMEAIKAKQAEAISKRQEERNK 319
+ E ++A +K+R Q E +K K+ + K +++ K
Sbjct: 195 SSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 42.4 bits (98), Expect = 7e-04
Identities = 38/137 (27%), Positives = 62/137 (45%), Gaps = 7/137 (5%)
Query: 247 KHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQ 306
+HK+ K+ + K+KT K+ + DKE E ++A+ + K E
Sbjct: 53 EHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEK-VRASGDAKIKKEKENGFS 111
Query: 307 AEAISKRQEERNKAFIPPKE--KPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAE 364
+ K + E + F+PPKE KP+ +P++ E D K K + K +K L E
Sbjct: 112 SPPQIKDEPEDDGYFVPPKEDIKPLKRPRD---EDDADYKPKKIKTEDTKKEKKRKLEEE 168
Query: 365 EIALKMEADEKKKKKKK 381
E K++ + K K KK
Sbjct: 169 EDG-KLKKPKNKDKDKK 184
Score = 28.9 bits (63), Expect = 8.0
Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 12/161 (7%)
Query: 208 DTMKNIHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKT-----V 262
D K+ H K K + + ++ + S E+ + K ++ KRKE K + +
Sbjct: 43 DREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKI 102
Query: 263 KKE----YTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEA-IKAKQAEAISKRQEER 317
KKE ++ P + E + D + +K ++ R + +A K K+ + ++E++
Sbjct: 103 KKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKK 162
Query: 318 NKAFIPPKEKPIVKPKEASTETKI-DVASIKEKVKKAKNKK 357
K ++ + KPK + K+ + + K+K KK + +K
Sbjct: 163 RK-LEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/178 (24%), Positives = 85/178 (47%), Gaps = 18/178 (10%)
Query: 217 YNIKSLMIKRELAKDSELRSQSWERF-LPQFKHK--------NVNKRKEPKKK----TVK 263
+ IK++ K+ K+ E + + E+ L + K K + +K+KE ++K TVK
Sbjct: 223 FKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVK 282
Query: 264 KEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIP 323
+ T P S+ E + KK++ + K ++ E ++++ +KA +
Sbjct: 283 SKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVK 342
Query: 324 PKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
++ + K KE K + +E++K+ ++L A EE L+ E E+KK+K+K
Sbjct: 343 AMQEALAKLKEEEERQKREE---EERIKRL--EELEAKRKEEERLEQEKRERKKQKEK 395
Score = 31.2 bits (69), Expect = 1.6
Identities = 27/139 (19%), Positives = 57/139 (41%), Gaps = 11/139 (7%)
Query: 253 KRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISK 312
K+ + KKK K+E P K + LK ++++++ E + K+ E +
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEA 374
Query: 313 RQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGAL----------- 361
+++E + +E+ K KE K + + + ++A+ + L
Sbjct: 375 KRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVP 434
Query: 362 TAEEIALKMEADEKKKKKK 380
+ + + K E KK+KK
Sbjct: 435 SKDSLPKKRPIYEDKKRKK 453
Score = 29.3 bits (64), Expect = 6.2
Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 4/122 (3%)
Query: 263 KKEYTPFPPPQPESQIDKELAS-GEYFLKANQKKRQKMEAIKAK-QAEAISKRQEERNKA 320
+KE TP PP +PE + D E A ++ A+ ++ +K+E K + + + +EE +
Sbjct: 482 EKEETP-PPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEE 540
Query: 321 FIPPKEKPIVKPKEASTE-TKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKK 379
+E + +E +E ++ D K +K K L ++E++ E D +
Sbjct: 541 EEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRT 600
Query: 380 KK 381
K+
Sbjct: 601 KE 602
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/213 (23%), Positives = 82/213 (38%), Gaps = 30/213 (14%)
Query: 195 PFSGLKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSEL---RSQSWERFLPQFKHKNV 251
P + KE+ +V MK + + S I+ E K +E RS+S R + K+
Sbjct: 268 PQAAAKELEEV----MKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH 323
Query: 252 NKRKEPKKK----------TVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEA 301
++RK + K + +K+ P + +E + K++ E
Sbjct: 324 SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 383
Query: 302 IKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKK--------- 352
IK K+ R++ER + KEK K K+ E + D KEK ++
Sbjct: 384 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 443
Query: 353 ----AKNKKLGALTAEEIALKMEADEKKKKKKK 381
K K+ E E DEK+KK KK
Sbjct: 444 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK 476
Score = 38.5 bits (88), Expect = 0.010
Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Query: 225 KRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELAS 284
+R + RS+S ER + + + +KRK+ ++K +KE + E + +KE
Sbjct: 348 RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREK 407
Query: 285 G-EYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDV 343
E ++ K ++ + K K+ + +R++E K KEK K KE + ++
Sbjct: 408 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 467
Query: 344 ASIKEKVKKAK 354
++K KK++
Sbjct: 468 DEKRKKDKKSR 478
Score = 32.0 bits (71), Expect = 0.95
Identities = 29/139 (20%), Positives = 64/139 (46%), Gaps = 7/139 (5%)
Query: 235 RSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQK 294
RS S ER + + + R KT+K++ + P P+ ++ DK+ + + ++
Sbjct: 491 RSSSRER---RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI-SERR 546
Query: 295 KRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASI-KEKVKKA 353
+R++ +++ + K + E+N + KEK K ++S ++D + + K
Sbjct: 547 ERERSTSMRKSSNDRDGKEKLEKNSTSL--KEKEHNKEPDSSVSKEVDDKDAPRTEENKI 604
Query: 354 KNKKLGALTAEEIALKMEA 372
++ L E ++ K EA
Sbjct: 605 QHNGNCQLNEENLSTKTEA 623
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/213 (23%), Positives = 82/213 (38%), Gaps = 30/213 (14%)
Query: 195 PFSGLKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSEL---RSQSWERFLPQFKHKNV 251
P + KE+ +V MK + + S I+ E K +E RS+S R + K+
Sbjct: 152 PQAAAKELEEV----MKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH 207
Query: 252 NKRKEPKKK----------TVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEA 301
++RK + K + +K+ P + +E + K++ E
Sbjct: 208 SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 267
Query: 302 IKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKK--------- 352
IK K+ R++ER + KEK K K+ E + D KEK ++
Sbjct: 268 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 327
Query: 353 ----AKNKKLGALTAEEIALKMEADEKKKKKKK 381
K K+ E E DEK+KK KK
Sbjct: 328 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK 360
Score = 38.5 bits (88), Expect = 0.010
Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Query: 225 KRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELAS 284
+R + RS+S ER + + + +KRK+ ++K +KE + E + +KE
Sbjct: 232 RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREK 291
Query: 285 G-EYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDV 343
E ++ K ++ + K K+ + +R++E K KEK K KE + ++
Sbjct: 292 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 351
Query: 344 ASIKEKVKKAK 354
++K KK++
Sbjct: 352 DEKRKKDKKSR 362
Score = 32.0 bits (71), Expect = 0.95
Identities = 29/139 (20%), Positives = 64/139 (46%), Gaps = 7/139 (5%)
Query: 235 RSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQK 294
RS S ER + + + R KT+K++ + P P+ ++ DK+ + + ++
Sbjct: 375 RSSSRER---RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI-SERR 430
Query: 295 KRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASI-KEKVKKA 353
+R++ +++ + K + E+N + KEK K ++S ++D + + K
Sbjct: 431 ERERSTSMRKSSNDRDGKEKLEKNSTSL--KEKEHNKEPDSSVSKEVDDKDAPRTEENKI 488
Query: 354 KNKKLGALTAEEIALKMEA 372
++ L E ++ K EA
Sbjct: 489 QHNGNCQLNEENLSTKTEA 507
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Query: 227 ELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGE 286
E+ D E E + F + KRKE K+ KE + SQ+D E+ S E
Sbjct: 2173 EVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKE-------KFSSQVD-EVESEE 2224
Query: 287 YFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASI 346
+F + + ++E ++ +E +R+EE + +E+ + +E E K
Sbjct: 2225 HFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE 2284
Query: 347 KEKVKKAKNKKLGALTAEEIALKMEADEKKKK 378
+EK KK K KK EE+ K E E+K++
Sbjct: 2285 EEKKKKKKEKK-----KEEVQEKEEVFEEKEE 2311
Score = 32.0 bits (71), Expect = 0.95
Identities = 43/233 (18%), Positives = 98/233 (42%), Gaps = 22/233 (9%)
Query: 150 LVRNKERFVKRRQRLIGPKGSTLKALELLT-NCYIMVQGNTVSAIGPFSGLKEVRKVVLD 208
L R +E+ ++++ +L + + ++E LT N I+ Q ++ L + ++ +
Sbjct: 1798 LGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQ--EKKNLAQEKEKLAQ 1855
Query: 209 TMKNIHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTP 268
+N+ +YN + L ++ + + + + L Q + K +++ KK K T
Sbjct: 1856 RKENL--LYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAET- 1912
Query: 269 FPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKP 328
+K+L E L Q+K + + A + + ++ R + I +EK
Sbjct: 1913 ----------EKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKA 1962
Query: 329 IVKPKEASTETKIDVASIKEKVKK------AKNKKLGALTAEEIALKMEADEK 375
+ + E K+ + KE + K ++ +K+ + E K+ +EK
Sbjct: 1963 LNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEK 2015
Score = 32.0 bits (71), Expect = 0.95
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 8/109 (7%)
Query: 273 QPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKP 332
+ E + ++E E ++ +++R++ E + KQ E ++EE K K+K V+
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE----KEEEEKKKKKKEKKKEEVQE 2301
Query: 333 KEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
KE E K ++ S +E + ++ E +L+ E D +K+ KK
Sbjct: 2302 KEEVFEEKEEIMSEEETESLSDEEE----EEESCSLEEEVDREKEILKK 2346
Score = 31.2 bits (69), Expect = 1.6
Identities = 36/153 (23%), Positives = 65/153 (42%), Gaps = 21/153 (13%)
Query: 225 KRELAKDSELRSQSWERFLPQFKHKNVNKRK----EPKKKTVKKEYTPFPPPQPESQIDK 280
++ELA+ EL W+ +K + +N+ + E KKK ++E + S+ +
Sbjct: 1711 EKELAQ--ELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEET 1768
Query: 281 ELASGEYFLKANQKKR---------------QKMEAIKAKQAEAISKRQEERNKAFIPPK 325
+LA E L ++K +K E + K+ + KR+ N K
Sbjct: 1769 KLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTK 1828
Query: 326 EKPIVKPKEASTETKIDVASIKEKVKKAKNKKL 358
K I+ K+ + K ++A KEK+ + K L
Sbjct: 1829 NKMILYQKKNLAQEKKNLAQEKEKLAQRKENLL 1861
>gi|10047140 partner of NOB1 [Homo sapiens]
Length = 252
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 3/145 (2%)
Query: 65 PKYREAYLKECWPLVQKALNEH-HVNATLDLIEGSMTVCTTKKTFDPYIIIRARDLIKLL 123
P R LKE W + + EH + +L ++ + T K+T D + +A D +K
Sbjct: 81 PANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKETKDVSALTKAADFVKAF 140
Query: 124 ARSVSFEQAVRILQ-DDVACDIIKIGSLVRNKERFVKRR-QRLIGPKGSTLKALELLTNC 181
E A+ +++ DD+ + +I + K + R R+ G G T +E +T
Sbjct: 141 ILGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRT 200
Query: 182 YIMVQGNTVSAIGPFSGLKEVRKVV 206
I++ V +G F +K R +
Sbjct: 201 RIVLADVKVHILGSFQNIKMARTAI 225
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 39.7 bits (91), Expect = 0.005
Identities = 48/189 (25%), Positives = 84/189 (44%), Gaps = 20/189 (10%)
Query: 199 LKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHK----NVNKR 254
LKE+ K + +K +IK+L+ RE +L++Q L + H+ +NK
Sbjct: 883 LKELEKENKELVKRA--TIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKE 940
Query: 255 KEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKA-----------NQKKRQKMEAIK 303
+ + + + ES + K L E + A NQ+ RQ+++ +K
Sbjct: 941 RLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVK 1000
Query: 304 AKQAEAISKRQ-EERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALT 362
K EA+ +RQ EER PP K + S ET ++ +K+++ + + L
Sbjct: 1001 -KNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN-ATLQ 1058
Query: 363 AEEIALKME 371
AE+ ALK +
Sbjct: 1059 AEKQALKTQ 1067
Score = 30.0 bits (66), Expect = 3.6
Identities = 56/273 (20%), Positives = 117/273 (42%), Gaps = 14/273 (5%)
Query: 114 IRARDLIKLLARSVSFEQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLK 173
+R R I AR E+ +IL + + K+ S + ++R +K+ KG +
Sbjct: 570 LRQRSQISAEARVKDIEKENKILHESIKETSSKL-SKIEFEKRQIKKELEHYKEKGE--R 626
Query: 174 ALELLTNCYIMVQGNTVSAIGPFSGLK-EVRKVVLDTMKNIHPIYNIKSLMIKRELAKDS 232
A EL + + + N + + LK K+ +N + L + K+
Sbjct: 627 AEELENELHHLEKENELLQ-KKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNL 685
Query: 233 ELRSQSWERFLPQFKHKNVNKRKEPKK-KTVKKEYTPFPPPQPESQIDKE-LASGEYFLK 290
+ +S E+ Q +N+ R+ + K + E + +KE L G LK
Sbjct: 686 TFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLK 745
Query: 291 ANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKV 350
A+ KK +++E + Q I + +R + + K I + + + +++ ++++ +
Sbjct: 746 ASFKKTERLEV--SYQGLDI---ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNL 800
Query: 351 KKAK--NKKLGALTAEEIALKMEADEKKKKKKK 381
++ K +K+L L E +L+ E + +K KK+
Sbjct: 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 39.7 bits (91), Expect = 0.005
Identities = 37/163 (22%), Positives = 71/163 (43%), Gaps = 12/163 (7%)
Query: 226 RELAKDSELRSQSWERFLPQFKHK------NVNKRKEPKKKTVKKEYTPFPPPQPESQID 279
+ LA+ E +++W++ L + + K + +K+++ KKK KK S
Sbjct: 46 KALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS 105
Query: 280 KELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTET 339
+ E K K+R+K + K +E+ E +K + K+K + TE
Sbjct: 106 SSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKK-----SKDGTEK 160
Query: 340 KIDVASIKEKVKK-AKNKKLGALTAEEIALKMEADEKKKKKKK 381
+ D+ + +K K +++K L + + E E KKKK +
Sbjct: 161 EKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSE 203
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 39.7 bits (91), Expect = 0.005
Identities = 37/163 (22%), Positives = 71/163 (43%), Gaps = 12/163 (7%)
Query: 226 RELAKDSELRSQSWERFLPQFKHK------NVNKRKEPKKKTVKKEYTPFPPPQPESQID 279
+ LA+ E +++W++ L + + K + +K+++ KKK KK S
Sbjct: 56 KALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS 115
Query: 280 KELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTET 339
+ E K K+R+K + K +E+ E +K + K+K + TE
Sbjct: 116 SSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKK-----SKDGTEK 170
Query: 340 KIDVASIKEKVKK-AKNKKLGALTAEEIALKMEADEKKKKKKK 381
+ D+ + +K K +++K L + + E E KKKK +
Sbjct: 171 EKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSE 213
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 39.3 bits (90), Expect = 0.006
Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 6/128 (4%)
Query: 225 KRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELAS 284
K+E+ KD + + ER + + K +K KE K+ V+++ P + +I+K+
Sbjct: 140 KKEIHKDKTEKQEKPER---KIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKP 196
Query: 285 GEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNK---AFIPPKEKPIVKPKEASTETKI 341
L QKK + E + K + + ++E+ K A + +K KPKE + K
Sbjct: 197 ETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKA 256
Query: 342 DVASIKEK 349
V+ ++K
Sbjct: 257 AVSKHEQK 264
Score = 35.4 bits (80), Expect = 0.086
Identities = 42/164 (25%), Positives = 64/164 (39%), Gaps = 18/164 (10%)
Query: 228 LAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPP-------PQPESQIDK 280
+ KD E E+ K K +K+ K KE P PP +PE QI K
Sbjct: 469 ILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKK 528
Query: 281 ELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNK----AFIPPKEKPIVKPKEAS 336
E + + + K + +K ++ + K +E+ K I KP KP + +
Sbjct: 529 EAKPA----ISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKP--KPTKKA 582
Query: 337 TETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKK 380
+ + SIK K K +T E K E EK+ K+K
Sbjct: 583 EHREREPPSIKTDKPKPTPKGTSEVT-ESGKKKTEISEKESKEK 625
Score = 33.9 bits (76), Expect = 0.25
Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 8/116 (6%)
Query: 270 PPPQPESQIDKEL-ASGEYFLKANQKKRQKMEAI---KAKQAEAISKRQEERNKAFIPPK 325
PPP P Q + AS K +KK+ + + K K+ E I K+ E+ + K
Sbjct: 291 PPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKK 350
Query: 326 EKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
E + T A+ K+ KK +KK T + ++ +K++KK+K
Sbjct: 351 EPGKASETKQGTVKIAAQAAAKKDEKKEDSKK----TKKPAEVEQPKGKKQEKKEK 402
Score = 33.5 bits (75), Expect = 0.33
Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 21/222 (9%)
Query: 146 KIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTNCYIMVQGNTVSAIGPFSGLKEVRKV 205
K S++++KE + +++ P K E + + G V P K+ K
Sbjct: 465 KTSSILKDKEPIKGKEEKV--PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKP 522
Query: 206 VLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSW--ERFLPQFKHKNVNKRKEPKKKTVK 263
K P + K + K+++ K + S E+ L Q K + K +PK T K
Sbjct: 523 EPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKP-TKK 581
Query: 264 KEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQ--------AEAISKRQE 315
E+ PP ++ K G + + KK+ ++ ++K+ E +S R+E
Sbjct: 582 AEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKE 641
Query: 316 ERNKAFIPPKEKPI--------VKPKEASTETKIDVASIKEK 349
+ EKP V + + E DV+ K+K
Sbjct: 642 SLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQK 683
Score = 33.1 bits (74), Expect = 0.43
Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 10/90 (11%)
Query: 292 NQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVK 351
++ K +K E + K ++ +++E+ K + KEKP K+A+ + KI+ E
Sbjct: 144 HKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKP---EKKATHKEKIEKKEKPETKT 200
Query: 352 KAKNKKLGALTAEEIALKMEADEKKKKKKK 381
AK +K A TAE+ ++EK KK+ K
Sbjct: 201 LAKEQKK-AKTAEK------SEEKTKKEVK 223
Score = 33.1 bits (74), Expect = 0.43
Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 17/150 (11%)
Query: 234 LRSQSWERFLPQFKHKNVNKRKEP---KKKTVKKEYTPFPPPQPESQIDKELASGEYFLK 290
L + E+ + K + K+KE KKK+ K+ +P + + + + +
Sbjct: 309 LEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQ 368
Query: 291 ANQKKRQKMEAIK-----AKQAEAISKRQEERNK----AFIPPKEKPI-----VKPKEAS 336
A KK +K E K A+ + K+QE++ K A P KE + VK K
Sbjct: 369 AAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTER 428
Query: 337 TETKIDVASIKEKVKKAKNKKLGALTAEEI 366
+ +I SIK+ V K +K +EI
Sbjct: 429 AKEEIGAVSIKKAVPGKKEEKTTKTVEQEI 458
>gi|169183877 PREDICTED: similar to hCG1742476 [Homo sapiens]
Length = 278
Score = 38.9 bits (89), Expect = 0.008
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 256 EPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQE 315
+PKKK +K P P+ K+ ++ F K N++K E + + E +
Sbjct: 115 KPKKKKKQK-----PQEAPQENGIKDPSNS--FSKPNKRKSFSKEKLVSSHREETAGSIS 167
Query: 316 ERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEK 375
N+ PKE+ + PKEA + V K +K K+L + EE A + +K
Sbjct: 168 LPNRKTSSPKEEAVNDPKEAGNRS---VTKKKTGNSPSKRKELVSSGPEEAAGSKSSSKK 224
Query: 376 KKKKKK 381
KKK K
Sbjct: 225 KKKLHK 230
Score = 32.0 bits (71), Expect = 0.95
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Query: 275 ESQIDKELA---SGEYFLKANQKKRQKMEAIKAKQAEAISKRQ-----EERNKAFIPPKE 326
+ Q+++ L+ +GE K + +M + AE I K + EE K + PK+
Sbjct: 59 QEQVEERLSFYETGEILSKKMDVMKTEMVQAEKTAAEIIRKLEKQETPEECAKTSVKPKK 118
Query: 327 KPIVKPKEASTETKI-DVASIKEKVKKAKN---KKLGALTAEEIALKMEADEKKKKKKK 381
K KP+EA E I D ++ K K K+ +KL + EE A + +K K
Sbjct: 119 KKKQKPQEAPQENGIKDPSNSFSKPNKRKSFSKEKLVSSHREETAGSISLPNRKTSSPK 177
>gi|169179771 PREDICTED: similar to hCG1742476 [Homo sapiens]
Length = 278
Score = 38.9 bits (89), Expect = 0.008
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 256 EPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQE 315
+PKKK +K P P+ K+ ++ F K N++K E + + E +
Sbjct: 115 KPKKKKKQK-----PQEAPQENGIKDPSNS--FSKPNKRKSFSKEKLVSSHREETAGSIS 167
Query: 316 ERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEK 375
N+ PKE+ + PKEA + V K +K K+L + EE A + +K
Sbjct: 168 LPNRKTSSPKEEAVNDPKEAGNRS---VTKKKTGNSPSKRKELVSSGPEEAAGSKSSSKK 224
Query: 376 KKKKKK 381
KKK K
Sbjct: 225 KKKLHK 230
Score = 32.0 bits (71), Expect = 0.95
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Query: 275 ESQIDKELA---SGEYFLKANQKKRQKMEAIKAKQAEAISKRQ-----EERNKAFIPPKE 326
+ Q+++ L+ +GE K + +M + AE I K + EE K + PK+
Sbjct: 59 QEQVEERLSFYETGEILSKKMDVMKTEMVQAEKTAAEIIRKLEKQETPEECAKTSVKPKK 118
Query: 327 KPIVKPKEASTETKI-DVASIKEKVKKAKN---KKLGALTAEEIALKMEADEKKKKKKK 381
K KP+EA E I D ++ K K K+ +KL + EE A + +K K
Sbjct: 119 KKKQKPQEAPQENGIKDPSNSFSKPNKRKSFSKEKLVSSHREETAGSISLPNRKTSSPK 177
>gi|239743692 PREDICTED: hypothetical protein LOC402360 [Homo
sapiens]
Length = 278
Score = 38.9 bits (89), Expect = 0.008
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 256 EPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQE 315
+PKKK +K P P+ K+ ++ F K N++K E + + E +
Sbjct: 115 KPKKKKKQK-----PQEAPQENGIKDPSNS--FSKPNKRKSFSKEKLVSSHREETAGSIS 167
Query: 316 ERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEK 375
N+ PKE+ + PKEA + V K +K K+L + EE A + +K
Sbjct: 168 LPNRKTSSPKEEAVNDPKEAGNRS---VTKKKTGNSPSKRKELVSSGPEEAAGSKSSSKK 224
Query: 376 KKKKKK 381
KKK K
Sbjct: 225 KKKLHK 230
Score = 32.0 bits (71), Expect = 0.95
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Query: 275 ESQIDKELA---SGEYFLKANQKKRQKMEAIKAKQAEAISKRQ-----EERNKAFIPPKE 326
+ Q+++ L+ +GE K + +M + AE I K + EE K + PK+
Sbjct: 59 QEQVEERLSFYETGEILSKKMDVMKTEMVQAEKTAAEIIRKLEKQETPEECAKTSVKPKK 118
Query: 327 KPIVKPKEASTETKI-DVASIKEKVKKAKN---KKLGALTAEEIALKMEADEKKKKKKK 381
K KP+EA E I D ++ K K K+ +KL + EE A + +K K
Sbjct: 119 KKKQKPQEAPQENGIKDPSNSFSKPNKRKSFSKEKLVSSHREETAGSISLPNRKTSSPK 177
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 38.9 bits (89), Expect = 0.008
Identities = 50/191 (26%), Positives = 86/191 (45%), Gaps = 23/191 (12%)
Query: 199 LKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHK----NVNKR 254
LKE+ K + +K +IK+L+ RE +L++Q L + H+ +NK
Sbjct: 883 LKELEKENKELVKRA--TIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKE 940
Query: 255 K--EPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKA-----------NQKKRQKMEA 301
+ ++ T Y + ES + K L E + A NQ+ RQ+++
Sbjct: 941 RLLHDEQSTDDSRYKLLES-KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT 999
Query: 302 IKAKQAEAISKRQ-EERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKAKNKKLGA 360
+K K EA+ +RQ EER PP K + S ET ++ +K+++ + +
Sbjct: 1000 VK-KNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN-AT 1057
Query: 361 LTAEEIALKME 371
L AE+ ALK +
Sbjct: 1058 LQAEKQALKTQ 1068
Score = 30.0 bits (66), Expect = 3.6
Identities = 56/273 (20%), Positives = 117/273 (42%), Gaps = 14/273 (5%)
Query: 114 IRARDLIKLLARSVSFEQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLK 173
+R R I AR E+ +IL + + K+ S + ++R +K+ KG +
Sbjct: 570 LRQRSQISAEARVKDIEKENKILHESIKETSSKL-SKIEFEKRQIKKELEHYKEKGE--R 626
Query: 174 ALELLTNCYIMVQGNTVSAIGPFSGLK-EVRKVVLDTMKNIHPIYNIKSLMIKRELAKDS 232
A EL + + + N + + LK K+ +N + L + K+
Sbjct: 627 AEELENELHHLEKENELLQ-KKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNL 685
Query: 233 ELRSQSWERFLPQFKHKNVNKRKEPKK-KTVKKEYTPFPPPQPESQIDKE-LASGEYFLK 290
+ +S E+ Q +N+ R+ + K + E + +KE L G LK
Sbjct: 686 TFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLK 745
Query: 291 ANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKV 350
A+ KK +++E + Q I + +R + + K I + + + +++ ++++ +
Sbjct: 746 ASFKKTERLEV--SYQGLDI---ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNL 800
Query: 351 KKAK--NKKLGALTAEEIALKMEADEKKKKKKK 381
++ K +K+L L E +L+ E + +K KK+
Sbjct: 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 38.9 bits (89), Expect = 0.008
Identities = 46/191 (24%), Positives = 86/191 (45%), Gaps = 21/191 (10%)
Query: 207 LDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFK--HKNVNKR-----KEPKK 259
LD K + +IK + K+E ++ ++ Q +E + K H+ +N R E +K
Sbjct: 786 LDLQKKSEALESIKQKLTKQE--EEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQK 843
Query: 260 KTVKKEYTPFPPPQPESQIDKELAS----GEYFLKANQKKRQKMEAIKAKQAEAISKRQE 315
++KE + ++ K S F K NQK + + ++ E + Q
Sbjct: 844 VKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQV 903
Query: 316 ERNKAFIPPKE--KPIVKPKEASTETKIDVASIKEKVKKAKN------KKLGALTAEEIA 367
+ KE K + K KEAS + K+++ S++E++ +A+N K+ L
Sbjct: 904 QMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINE 963
Query: 368 LKMEADEKKKK 378
LK +++KKK+
Sbjct: 964 LKQSSEQKKKQ 974
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 38.5 bits (88), Expect = 0.010
Identities = 53/246 (21%), Positives = 102/246 (41%), Gaps = 46/246 (18%)
Query: 130 EQAVRILQDDVACDIIKIGSLVRNKERFVKRRQRLIGPKGSTLKALELLTNCYIMVQGNT 189
E ++I + V D+I L N E ++ + ++I K T K L+ L
Sbjct: 203 ELQMKITKQQVFIDVIN--KLKENVEELIEDKYKIILEKNDTKKTLQNL----------- 249
Query: 190 VSAIGPFSGLKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHK 249
+V+ +T K++ N K M++ + K ER++ + + K
Sbjct: 250 -------------EEVLANTQKHLQESRNDKE-MLQLQFKKIKANYVCLQERYMTEMQQK 295
Query: 250 N--VNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKAN-----------QKKR 296
N V++ E K KKE Q + +++K AS LK Q++
Sbjct: 296 NKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEF 355
Query: 297 QKMEAIKAKQAEAISKRQEE-----RNKAFIPPKEK-PIVKPKEASTETKIDVASIKEKV 350
QK+E ++ + + R E+ RN F+ E+ +K ++ E K + A +K++V
Sbjct: 356 QKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQV 415
Query: 351 KKAKNK 356
+++ +
Sbjct: 416 ARSEEQ 421
>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
Length = 1012
Score = 38.5 bits (88), Expect = 0.010
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 24/168 (14%)
Query: 219 IKSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQI 278
IK KRE+ + +LR++ ++ L FK + K K KK +KE T F Q
Sbjct: 198 IKLNEYKREI--EEQLRAEMCQK-LKFFKDTEIAKIKMEAKKKYEKELTMF-------QN 247
Query: 279 DKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPP-----KEKPIVKPK 333
D F KA Q K + + + E I K QE K K+ +++ +
Sbjct: 248 D--------FEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGR 299
Query: 334 EASTETKIDVASIKEKVKKAKNKKL-GALTAEEIALKMEADEKKKKKK 380
EA + +++ + +K+++ K+K + AL +E +K + +K K
Sbjct: 300 EAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLK 347
>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
sapiens]
Length = 373
Score = 38.5 bits (88), Expect = 0.010
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 20/136 (14%)
Query: 224 IKRELAKDSELRSQSWERFLPQFKHKN-VNKRKEPKKKTVKKEYTPFPPPQPESQIDKEL 282
+ ++L K E+ + + + + KHK V K+ E K+K +++ + E + KEL
Sbjct: 168 LNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINK----EMEEKAAKEL 223
Query: 283 ASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKID 342
EY + ++K Q E +K K AE ++++E+ K K ++A + K +
Sbjct: 224 EK-EYLQEKAKEKYQ--EWLKKKNAEECERKKKEKEKE----------KQQQAEIQEKKE 270
Query: 343 VASIK--EKVKKAKNK 356
+A K E ++ AK+K
Sbjct: 271 IAEKKFQEWLENAKHK 286
Score = 35.4 bits (80), Expect = 0.086
Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 13/103 (12%)
Query: 289 LKANQKKRQKMEAIKAKQAEAISKRQ---EERNKAFIPPK--------EKPIVKPKEAST 337
LKA ++ Q++E K K+ E KR+ EE++K ++ K E+ I K E
Sbjct: 162 LKALEELNQQLE--KRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKA 219
Query: 338 ETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKK 380
+++ ++EK K+ + L AEE K + EK+K+++
Sbjct: 220 AKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQ 262
Score = 28.9 bits (63), Expect = 8.0
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 294 KKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEASTETKIDVASIKEKVKKA 353
K++++ + ++ K E ++++ E+R + K K I + K K + KE+ +K
Sbjct: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKI 211
Query: 354 KNKKLGALTAEEIALKMEADEKKKKK 379
NK++ A+E+ K EK K+K
Sbjct: 212 -NKEMEEKAAKELE-KEYLQEKAKEK 235
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 37.7 bits (86), Expect = 0.017
Identities = 27/105 (25%), Positives = 58/105 (55%), Gaps = 12/105 (11%)
Query: 277 QIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKEAS 336
Q D+E + L+A +++++K++ +AK+A+ +K+++E K KEK + +E
Sbjct: 338 QRDQERLGKQLKLRAEREEKEKLKE-EAKRAKEEAKKKKEEEKEL---KEKERREKREKD 393
Query: 337 TETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
+ K + +KE+ +K + + L A K+E KK+++K+
Sbjct: 394 EKEKAEKQRLKEERRKERQEALEA--------KLEEKRKKEEEKR 430
Score = 35.4 bits (80), Expect = 0.086
Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 3/127 (2%)
Query: 191 SAIGPFSGLKEVRKVVLDTMKNIHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHKN 250
S+ PF +R++ +K ++ + L K +LR++ E+ + + K
Sbjct: 307 SSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKR 366
Query: 251 VNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAI 310
K + KKK +KE + + +KE A + + +K+RQ EA++AK E
Sbjct: 367 A-KEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQ--EALEAKLEEKR 423
Query: 311 SKRQEER 317
K +E+R
Sbjct: 424 KKEEEKR 430
Score = 33.1 bits (74), Expect = 0.43
Identities = 38/160 (23%), Positives = 62/160 (38%), Gaps = 32/160 (20%)
Query: 215 PIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQP 274
P+ I +K K+ + ER Q K + + KE K+ K+ +
Sbjct: 317 PLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKE 376
Query: 275 ESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKPKE 334
E + KE K ++KR+K E KA++ +R++ER +A
Sbjct: 377 EEKELKE--------KERREKREKDEKEKAEKQRLKEERRKERQEAL------------- 415
Query: 335 ASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADE 374
A ++EK KK + K+ L EE +K E E
Sbjct: 416 --------EAKLEEKRKKEEEKR---LREEEKRIKAEKAE 444
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 37.4 bits (85), Expect = 0.023
Identities = 43/229 (18%), Positives = 97/229 (42%), Gaps = 15/229 (6%)
Query: 153 NKERFVKRRQRLIGPKGSTLKALELLTNCYIMVQGNTVSAIGPFSGLKEVRKVVLDTMKN 212
NKER Q+ GP+G +ALE + + +A G + K T
Sbjct: 340 NKEREGTLAQQAAGPQGE--EALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDA 397
Query: 213 IHPIYNIKSLMIKRELAKDSELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPP 272
+ + L K+ E + + + + + + + ++ E ++ +++E
Sbjct: 398 GEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEE 457
Query: 273 QPESQIDKELASGEYFLKANQKKRQKMEAIKAKQAEAISKRQEERNKAFIPPKEKPIVKP 332
+ + +K+ GE KA ++ ++K E E + K ++E+ K +EK +++
Sbjct: 458 RKRQEEEKKKQEGEEKRKAGEEAKRKAE------EELLLKEKQEQEK-----QEKAMIEK 506
Query: 333 KEASTETKIDVASIKEKVKKAKNKKLGALTAEEIALKMEADEKKKKKKK 381
++ + ETK + E+++ + + + + E + K DE K+ +K
Sbjct: 507 QKEAAETK--AREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRK 553
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 37.0 bits (84), Expect = 0.030
Identities = 37/150 (24%), Positives = 71/150 (47%), Gaps = 4/150 (2%)
Query: 232 SELRSQSWERFLPQFKHKNVNKRKEPKKKTVKKEYTPFPPPQPESQIDKELASGEYFLKA 291
+EL+ E+ + + K NK +K+ +KE +++KEL S + ++
Sbjct: 336 TELKDNHCEQLRVKIR-KLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQ 394
Query: 292 NQKKRQKMEAIKAKQAEAISKRQEE-RNKAFIPPKEKPIVKPKEASTETKIDVAS-IKEK 349
+KKR+ +E + K E + +E+ R +A + KP +K E +T + ++ + E
Sbjct: 395 EKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET 454
Query: 350 VKKAKNKKLGALTAEEIA-LKMEADEKKKK 378
+K L +EIA L++E D K +
Sbjct: 455 DEKEDLLHENRLMQDEIARLRLEKDTIKNQ 484
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,671,285
Number of Sequences: 37866
Number of extensions: 684644
Number of successful extensions: 4191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 296
Number of HSP's that attempted gapping in prelim test: 3352
Number of HSP's gapped (non-prelim): 845
length of query: 381
length of database: 18,247,518
effective HSP length: 104
effective length of query: 277
effective length of database: 14,309,454
effective search space: 3963718758
effective search space used: 3963718758
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.