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Search of human proteins with 10863887
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10863887 claudin 1 [Homo sapiens]
(211 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10863887 claudin 1 [Homo sapiens] 429 e-120
gi|153792186 claudin 7 [Homo sapiens] 276 1e-74
gi|183979975 claudin 19 isoform b [Homo sapiens] 260 5e-70
gi|183979973 claudin 19 isoform a [Homo sapiens] 259 1e-69
gi|4502877 claudin 4 [Homo sapiens] 213 7e-56
gi|4502875 claudin 3 [Homo sapiens] 213 7e-56
gi|11141861 claudin 9 [Homo sapiens] 210 8e-55
gi|153792768 claudin 6 [Homo sapiens] 199 1e-51
gi|195947374 claudin 5 [Homo sapiens] 198 2e-51
gi|195947372 claudin 5 [Homo sapiens] 198 2e-51
gi|225703142 claudin 14 [Homo sapiens] 192 2e-49
gi|21536294 claudin 14 [Homo sapiens] 192 2e-49
gi|225703138 claudin 14 [Homo sapiens] 192 2e-49
gi|6912314 claudin 14 [Homo sapiens] 192 2e-49
gi|225703140 claudin 14 [Homo sapiens] 192 2e-49
gi|6912316 claudin 17 [Homo sapiens] 176 2e-44
gi|40788011 claudin 8 [Homo sapiens] 171 3e-43
gi|9966781 claudin 2 [Homo sapiens] 157 6e-39
gi|47716519 claudin 20 [Homo sapiens] 147 8e-36
gi|5921465 claudin 10 isoform b [Homo sapiens] 139 1e-33
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 139 2e-33
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 137 7e-33
gi|7656981 claudin 15 [Homo sapiens] 137 9e-33
gi|33598916 claudin 10 isoform a [Homo sapiens] 129 2e-30
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 129 2e-30
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 129 2e-30
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 126 1e-29
gi|162417973 claudin 22 [Homo sapiens] 120 1e-27
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 112 3e-25
gi|157820127 claudin-like [Homo sapiens] 111 5e-25
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 429 bits (1102), Expect = e-120
Identities = 211/211 (100%), Positives = 211/211 (100%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
Query: 181 LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV 211
LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
Sbjct: 181 LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV 211
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 276 bits (705), Expect = 1e-74
Identities = 129/213 (60%), Positives = 169/213 (79%), Gaps = 4/213 (1%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MAN+GLQLLGF +A LGW+G + TA+PQW++ SYAGDNI+TAQAMY+GLWM CV+QSTG
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
+ CK++DS+L LS+ LQATRALMVV ++LG +A+FVAT+GMKC +C DD+V+K R+A+
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
GG IF++AGLA LVA +WYG++IV +FY+P+ P N +YEFG A+F GWA ++L +LGGA
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
Query: 181 LLCCSCP--RKTTSYPTPRPYPKPAPSSGKDYV 211
LL CSCP Y PR YPK +S K+YV
Sbjct: 181 LLSCSCPGNESKAGYRVPRSYPK--SNSSKEYV 211
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 260 bits (665), Expect = 5e-70
Identities = 121/212 (57%), Positives = 159/212 (75%), Gaps = 2/212 (0%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MAN+GLQLLG+ LA GW+G I STALPQW+ SYAGD I+TA +YEGLWMSC SQSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Q+QCK++DSLL L +Q+ RALMVV +LLG +A+ ++ VGMKC + + + + K R+A+
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
GGA+F+LAGL L A +WY + QEF++P TPVNARYEFG ALF GWA+A L +LGG+
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 181 LLCCSCPRKTTSYPTPRPYPKPAPS-SGKDYV 211
LCC+CP +P+PY +P PS + ++YV
Sbjct: 181 FLCCTCPEPERPNSSPQPY-RPGPSAAAREYV 211
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 259 bits (662), Expect = 1e-69
Identities = 119/206 (57%), Positives = 155/206 (75%), Gaps = 1/206 (0%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MAN+GLQLLG+ LA GW+G I STALPQW+ SYAGD I+TA +YEGLWMSC SQSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Q+QCK++DSLL L +Q+ RALMVV +LLG +A+ ++ VGMKC + + + + K R+A+
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
GGA+F+LAGL L A +WY + QEF++P TPVNARYEFG ALF GWA+A L +LGG+
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 181 LLCCSCPRKTTSYPTPRPYPKPAPSS 206
LCC+CP +P+PY +P PS+
Sbjct: 181 FLCCTCPEPERPNSSPQPY-RPGPSA 205
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 213 bits (543), Expect = 7e-56
Identities = 97/211 (45%), Positives = 142/211 (67%), Gaps = 2/211 (0%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+ GLQ++G LA LGW+ ++ ALP WR+ ++ G NIVT+Q ++EGLWM+CV QSTG
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Q+QCKV+DSLL L LQA RAL+++ I++ + + ++ VG KC CLE DE K + +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLE-DESAKAKTMI 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
+ G +FLLAGL ++V +W + I+Q+FY+P+ + E G +L+ GWAA+ L LLGG
Sbjct: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179
Query: 181 LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV 211
LLCC+CP +T P Y ++ +YV
Sbjct: 180 LLCCNCPPRTDK-PYSAKYSAARSAAASNYV 209
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 213 bits (543), Expect = 7e-56
Identities = 101/203 (49%), Positives = 136/203 (66%), Gaps = 1/203 (0%)
Query: 5 GLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQC 64
GL++ G LA LGW+G IV ALP WR+ ++ G NI+T+Q ++EGLWM+CV QSTGQ+QC
Sbjct: 4 GLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQC 63
Query: 65 KVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGA 124
KV+DSLL L LQA RAL+VV ILL + VA VG +C C++DD K ++ ++ G
Sbjct: 64 KVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGV 122
Query: 125 IFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCC 184
+FLLA L LV +W N I+++FY+P+ P + E G L+ GWAAA+L LLGGALLCC
Sbjct: 123 LFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCC 182
Query: 185 SCPRKTTSYPTPRPYPKPAPSSG 207
SCP + Y + S+G
Sbjct: 183 SCPPREKKYTATKVVYSAPRSTG 205
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 210 bits (534), Expect = 8e-55
Identities = 105/218 (48%), Positives = 145/218 (66%), Gaps = 8/218 (3%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+ GL+LLG LA LGW+G +VS ALP W++ ++ G++IV AQ ++EGLWMSCV QSTG
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Q+QCKV+DSLL L LQA RAL V+ +LL ++ + VA G +C C+E DE K R+ +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVE-DEGAKARIVL 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
G I LLAG+ +L+ W + I+Q+FY+P+ + E G +L+ GWAAA+L +LGG
Sbjct: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179
Query: 181 LLCCSCPRKTTSYPT-PR---PYPKPAPSSG---KDYV 211
LLCC+CP P PR P + +SG +DYV
Sbjct: 180 LLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV 217
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 199 bits (507), Expect = 1e-51
Identities = 96/223 (43%), Positives = 142/223 (63%), Gaps = 15/223 (6%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+AG+Q+LG +L LGW+ +VS ALP W++ ++ G++IV AQ ++EGLWMSCV QSTG
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Q+QCKV+DSLL L LQA RAL V+ +L+ + + V G KC C+E+ + K R+ +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKD-SKARLVL 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
G +F+++G+ L+ W + I+++FY+P+ + E G +L+ GWAA+ L LLGG
Sbjct: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
Query: 181 LLCCSCP------------RKTTSYPTPRPYPKPAPSSGKDYV 211
LLCC+CP R +TS P P P+ K+YV
Sbjct: 180 LLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPT--KNYV 220
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 198 bits (504), Expect = 2e-51
Identities = 97/219 (44%), Positives = 138/219 (63%), Gaps = 9/219 (4%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
M +A L++LG +L +GW G I++ LP W++ ++ NIVTAQ ++GLWMSCV QSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
+QCKV+DS+L LS+ +QA RAL V +LL +A+FV G +C C+ K R+A+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPA-KARVAL 204
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
GG ++L GL LV W+ N +V+EFYDP PV+ +YE G AL+ GWAA +L ++GG
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
Query: 181 LLCCSC----PRKTTSYPTPRPYPKPAPSSG----KDYV 211
LLCC R S+P P+ ++G K+YV
Sbjct: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKKNYV 303
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 198 bits (504), Expect = 2e-51
Identities = 97/219 (44%), Positives = 138/219 (63%), Gaps = 9/219 (4%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
M +A L++LG +L +GW G I++ LP W++ ++ NIVTAQ ++GLWMSCV QSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
+QCKV+DS+L LS+ +QA RAL V +LL +A+FV G +C C+ K R+A+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPA-KARVAL 204
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
GG ++L GL LV W+ N +V+EFYDP PV+ +YE G AL+ GWAA +L ++GG
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
Query: 181 LLCCSC----PRKTTSYPTPRPYPKPAPSSG----KDYV 211
LLCC R S+P P+ ++G K+YV
Sbjct: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKKNYV 303
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 192 bits (488), Expect = 2e-49
Identities = 99/221 (44%), Positives = 139/221 (62%), Gaps = 14/221 (6%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+ +QLLGF+L+FLG +G +++T LP WR ++ G NI+TA + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
QC+++ SLL L LQA RALMV+ LL IA A +GMKC +C + K A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
+GG +F+LAGL +VA +W N +VQ FY+P+ P ++E GQAL+ G+ ++SL L+GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LLCCSC------------PRKTTSYPTPRPYPKPAPSSGKD 209
LLC SC PR TT+ P +P P++ KD
Sbjct: 180 LLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQP-PAAYKD 219
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 192 bits (488), Expect = 2e-49
Identities = 99/221 (44%), Positives = 139/221 (62%), Gaps = 14/221 (6%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+ +QLLGF+L+FLG +G +++T LP WR ++ G NI+TA + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
QC+++ SLL L LQA RALMV+ LL IA A +GMKC +C + K A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
+GG +F+LAGL +VA +W N +VQ FY+P+ P ++E GQAL+ G+ ++SL L+GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LLCCSC------------PRKTTSYPTPRPYPKPAPSSGKD 209
LLC SC PR TT+ P +P P++ KD
Sbjct: 180 LLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQP-PAAYKD 219
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 192 bits (488), Expect = 2e-49
Identities = 99/221 (44%), Positives = 139/221 (62%), Gaps = 14/221 (6%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+ +QLLGF+L+FLG +G +++T LP WR ++ G NI+TA + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
QC+++ SLL L LQA RALMV+ LL IA A +GMKC +C + K A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
+GG +F+LAGL +VA +W N +VQ FY+P+ P ++E GQAL+ G+ ++SL L+GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LLCCSC------------PRKTTSYPTPRPYPKPAPSSGKD 209
LLC SC PR TT+ P +P P++ KD
Sbjct: 180 LLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQP-PAAYKD 219
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 192 bits (488), Expect = 2e-49
Identities = 99/221 (44%), Positives = 139/221 (62%), Gaps = 14/221 (6%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+ +QLLGF+L+FLG +G +++T LP WR ++ G NI+TA + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
QC+++ SLL L LQA RALMV+ LL IA A +GMKC +C + K A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
+GG +F+LAGL +VA +W N +VQ FY+P+ P ++E GQAL+ G+ ++SL L+GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LLCCSC------------PRKTTSYPTPRPYPKPAPSSGKD 209
LLC SC PR TT+ P +P P++ KD
Sbjct: 180 LLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQP-PAAYKD 219
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 192 bits (488), Expect = 2e-49
Identities = 99/221 (44%), Positives = 139/221 (62%), Gaps = 14/221 (6%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+ +QLLGF+L+FLG +G +++T LP WR ++ G NI+TA + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
QC+++ SLL L LQA RALMV+ LL IA A +GMKC +C + K A+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
+GG +F+LAGL +VA +W N +VQ FY+P+ P ++E GQAL+ G+ ++SL L+GG
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 LLCCSC------------PRKTTSYPTPRPYPKPAPSSGKD 209
LLC SC PR TT+ P +P P++ KD
Sbjct: 180 LLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQP-PAAYKD 219
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 176 bits (445), Expect = 2e-44
Identities = 80/200 (40%), Positives = 123/200 (61%), Gaps = 2/200 (1%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA LQ+ G +L FLG +G + +T LPQWR+ ++ G NI+ + ++EGLWM+C+ Q+
Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
++QCK + SLL L L+ RALM V + L +IA+ + GMK ++C +E K +
Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLG 120
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
G +F+L G+ +L+ +W N I+++FY+P + + E G ALF GWA+A++ +GG
Sbjct: 121 TSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGG 180
Query: 181 LLC--CSCPRKTTSYPTPRP 198
LLC C C RK Y P P
Sbjct: 181 LLCGFCCCNRKKQGYRYPVP 200
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 171 bits (434), Expect = 3e-43
Identities = 76/195 (38%), Positives = 122/195 (62%), Gaps = 2/195 (1%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA L++ G L +G +G + T +PQWR+ ++ +NIV + +EGLWM+CV Q+
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
++QCK++DSLL LS LQA R LM ++ +A +A +GMKC +C D+E K + +
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
G IF++ G+ +L+ +W N I+++FY+ + V + E G+AL+ GW A + ++GGA
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 181 LLCC--SCPRKTTSY 193
L CC C K++SY
Sbjct: 181 LFCCVFCCNEKSSSY 195
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 157 bits (397), Expect = 6e-39
Identities = 81/217 (37%), Positives = 122/217 (56%), Gaps = 17/217 (7%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+ GLQL+G+IL LG +G +V+ LP W+ SY G +IVTA +GLWM C + STG
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
QC ++ +LL L + +QA +A+MV + +A ++ VGM+C ++ K R+AV
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRA-KDRVAV 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
GG F+L GL + AW + I+++FY P+ P + ++E G+AL+ G ++ L+ G
Sbjct: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179
Query: 181 LLCCSC----------------PRKTTSYPTPRPYPK 201
+LC SC P T S P P PK
Sbjct: 180 ILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPK 216
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 147 bits (370), Expect = 8e-36
Identities = 78/202 (38%), Positives = 110/202 (54%), Gaps = 5/202 (2%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA+AGLQLL FILA G G + +T LP W++ NI+TA GLWM C STG
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
C + S+L+L +QA RA MV+ +L + I +TVGMKC + L D K +
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTR-LGGDRETKSHASF 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
GG F+ AG++ L++T WY I+ F D P + ++E G A++ G+ +A L + G
Sbjct: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
Query: 181 LLCCSC----PRKTTSYPTPRP 198
+ C SC P PT +P
Sbjct: 180 IFCTSCIKRNPEARLDPPTQQP 201
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 139 bits (351), Expect = 1e-33
Identities = 71/187 (37%), Positives = 109/187 (58%), Gaps = 7/187 (3%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQ--WRIYSYAGDNIVTAQAMYEGLWMSCVSQS 58
MA+ +++ F+++ GW+ +VS+ LP W++ + G ++T + LW +CV+ S
Sbjct: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDG-TVITTATYWANLWKACVTDS 57
Query: 59 TGQIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRM 118
TG CK F S+L L +QA R LM+ + LG A GMKC K D+ K ++
Sbjct: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKI 116
Query: 119 AVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLG 178
A + G +F+L+GL + + Y N+I EF+DP+ V +YE G ALF GWA ASLC++G
Sbjct: 117 ACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIG 175
Query: 179 GALLCCS 185
G + C S
Sbjct: 176 GVIFCFS 182
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 139 bits (349), Expect = 2e-33
Identities = 70/197 (35%), Positives = 109/197 (55%), Gaps = 12/197 (6%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
M+ Q++ F+L+ LG G I +T + W DN VT+ YEGLW SCV QS+G
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLY-DNPVTSVFQYEGLWRSCVRQSSG 59
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
+C+ + ++L L + LQA RALM+VGI+LG I + V+ +KC++ ++ K M +
Sbjct: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFY-----------DPMTPVNARYEFGQALFTGW 169
G +F+++GL + + + N +V F+ + V RY FG ALF GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 170 AAASLCLLGGALLCCSC 186
A L L+GG ++C +C
Sbjct: 180 VAGGLTLIGGVMMCIAC 196
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 137 bits (345), Expect = 7e-33
Identities = 71/197 (36%), Positives = 110/197 (55%), Gaps = 12/197 (6%)
Query: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
MA Q LGF+++ +G G I +T + QW +N VTA Y+GLW SCV +S+G
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLY-NNPVTAVFNYQGLWRSCVRESSG 59
Query: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
+C+ + +LL L + LQA RALM+VGI+LG I + V+ +KC++ ++ K M +
Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFY-----------DPMTPVNARYEFGQALFTGW 169
G +F+++GL + + + N +V F+ + V RY FG ALF GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 170 AAASLCLLGGALLCCSC 186
A L L+GG ++C +C
Sbjct: 180 VAGGLTLIGGVMMCIAC 196
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 137 bits (344), Expect = 9e-33
Identities = 70/200 (35%), Positives = 112/200 (56%), Gaps = 5/200 (2%)
Query: 6 LQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCK 65
++ GF +A +G + V+ WR+ + G N++T ++E LW SC + S G C
Sbjct: 5 VETFGFFMATVGLLMLGVTLPNSYWRVSTVHG-NVITTNTIFENLWFSCATDSLGVYNCW 63
Query: 66 VFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAI 125
F S+L LS +QA RALM+ ILLG + + + G++C + +K ++A GA+
Sbjct: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
Query: 126 FLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCS 185
+LAG+ +VA +WY I ++F+DP+ P +YE G AL+ GW+A+ + +LGG LC +
Sbjct: 124 HILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCLCSA 182
Query: 186 CPRKTTSYPTP---RPYPKP 202
C + P RPY P
Sbjct: 183 CCCGSDEDPAASARRPYQAP 202
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 129 bits (324), Expect = 2e-30
Identities = 63/175 (36%), Positives = 104/175 (59%), Gaps = 4/175 (2%)
Query: 12 ILAFLGWIGAIVS-TALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSL 70
+++ +G GA+V+ T +W++ + A +++TA +Y+GLWM+C + G C+ ++
Sbjct: 9 LVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCAGNALGSFHCRPHFTI 67
Query: 71 LNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAG 130
++ +QA R LM+ + LG A GMKC K D+ K ++A + G +F+L+G
Sbjct: 68 FKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKIACLAGIVFILSG 126
Query: 131 LAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCS 185
L + + Y N+I EF+DP+ V +YE G ALF GWA ASLC++GG + C S
Sbjct: 127 LCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFCFS 180
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 129 bits (323), Expect = 2e-30
Identities = 68/181 (37%), Positives = 105/181 (58%), Gaps = 4/181 (2%)
Query: 6 LQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCK 65
+Q +G +L+FLGWI +I++T LP W+ + ++ + GLW +CV Q +QCK
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 66 VFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAI 125
FDS L L + L+ +R LM + LG + + V+ G+ C++ E K R+ ++GG +
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 126 FLLAGLAILVATAWYGNRIVQEFYDPMTP-VNARYEFGQALFTGWAAASLCLLGGALLCC 184
+G+ LV +W ++ VQEF+D P R+EFG+ALF GW A LLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 185 S 185
+
Sbjct: 186 A 186
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 129 bits (323), Expect = 2e-30
Identities = 68/181 (37%), Positives = 105/181 (58%), Gaps = 4/181 (2%)
Query: 6 LQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCK 65
+Q +G +L+FLGWI +I++T LP W+ + ++ + GLW +CV Q +QCK
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 66 VFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAI 125
FDS L L + L+ +R LM + LG + + V+ G+ C++ E K R+ ++GG +
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 126 FLLAGLAILVATAWYGNRIVQEFYDPMTP-VNARYEFGQALFTGWAAASLCLLGGALLCC 184
+G+ LV +W ++ VQEF+D P R+EFG+ALF GW A LLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 185 S 185
+
Sbjct: 186 A 186
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 126 bits (317), Expect = 1e-29
Identities = 67/181 (37%), Positives = 104/181 (57%), Gaps = 4/181 (2%)
Query: 6 LQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCK 65
+Q +G +L+ LGWI +I++T LP W+ + ++ + GLW +CV Q +QCK
Sbjct: 9 MQSVGLLLSLLGWILSIITTYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 66 VFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAI 125
FDS L L + L+ +R LM + LG + + V+ G+ C++ E K R+ ++GG +
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 126 FLLAGLAILVATAWYGNRIVQEFYDPMTP-VNARYEFGQALFTGWAAASLCLLGGALLCC 184
+G+ LV +W ++ VQEF+D P R+EFG+ALF GW A LLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 185 S 185
+
Sbjct: 186 A 186
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 120 bits (300), Expect = 1e-27
Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 4/180 (2%)
Query: 7 QLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKV 66
QL G L+ LGW+ + ++ LP W+ + ++ + GLW +CV Q +QCK
Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCKD 66
Query: 67 FDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIF 126
FDS L L + L+ +R LM + LG + + V+ G+ C++ E K R+ ++GG +
Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
Query: 127 LLAGLAILVATAWYGNRIVQEFYDPMTP-VNARYEFGQALFTGWAAASLCLLGGALLCCS 185
+G+ LV +W ++ VQEF+D P R+EFG+ALF GW A LLGG LL C+
Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 112 bits (279), Expect = 3e-25
Identities = 61/175 (34%), Positives = 96/175 (54%), Gaps = 23/175 (13%)
Query: 12 ILAFLGWIGAIVS-TALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSL 70
+++ +G GA+V+ T +W++ + A +++TA +Y+GLWM+C
Sbjct: 9 LVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCAGY------------- 54
Query: 71 LNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAG 130
+QA R LM+ + LG A GMKC K D+ K ++A + G +F+L+G
Sbjct: 55 ------IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKIACLAGIVFILSG 107
Query: 131 LAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCS 185
L + + Y N+I EF+DP+ V +YE G ALF GWA ASLC++GG + C S
Sbjct: 108 LCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFCFS 161
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 111 bits (277), Expect = 5e-25
Identities = 64/194 (32%), Positives = 98/194 (50%), Gaps = 4/194 (2%)
Query: 4 AGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQ 63
A +QL G +L+ LGW+ + V+T LPQW+ + + + T G+W CV +
Sbjct: 7 AKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMET---WIMGIWEVCVDREEVATV 63
Query: 64 CKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGG 123
CK F+S L+L LQ R LMV LG++ + + + G +C + V K R+ ++G
Sbjct: 64 CKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGR 123
Query: 124 AIFLLAGLAILVATAWYGNRIVQEFYDPMTP-VNARYEFGQALFTGWAAASLCLLGGALL 182
+ A L+ +W + +Q+F+D P + R+EFG AL+ GWAA LGG LL
Sbjct: 124 TLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
Query: 183 CCSCPRKTTSYPTP 196
S P P
Sbjct: 184 IFSACLGKEDVPFP 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,936,342
Number of Sequences: 37866
Number of extensions: 341552
Number of successful extensions: 2377
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2280
Number of HSP's gapped (non-prelim): 74
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.