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Search of human proteins with 239748340
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239748340 PREDICTED: hypothetical protein XP_002346633 [Homo
sapiens]
(465 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239748340 PREDICTED: hypothetical protein XP_002346633 [Homo ... 931 0.0
gi|190358543 hypothetical protein LOC57654 [Homo sapiens] 546 e-155
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 43 5e-04
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 42 0.001
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 42 0.001
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 42 0.001
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 42 0.001
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 41 0.003
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 41 0.003
gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa... 39 0.010
gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s... 39 0.010
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 39 0.010
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 39 0.013
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 39 0.013
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.029
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 37 0.029
gi|168229156 NFKB activating protein [Homo sapiens] 37 0.038
gi|169168458 PREDICTED: hypothetical protein [Homo sapiens] 37 0.038
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.038
gi|239742749 PREDICTED: hypothetical protein XP_002342626 [Homo ... 37 0.038
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 37 0.038
gi|231570186 zinc finger CCCH-type containing 14 isoform 6 [Homo... 37 0.050
gi|231570121 zinc finger CCCH-type containing 14 isoform 5 [Homo... 37 0.050
gi|40804742 zinc finger CCCH-type containing 14 isoform 1 [Homo ... 37 0.050
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 37 0.050
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 37 0.050
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 37 0.050
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 37 0.050
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 37 0.050
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 37 0.050
>gi|239748340 PREDICTED: hypothetical protein XP_002346633 [Homo
sapiens]
Length = 465
Score = 931 bits (2406), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS
Sbjct: 1 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW
Sbjct: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
Query: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180
NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER
Sbjct: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180
Query: 181 EMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRT 240
EMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRT
Sbjct: 181 EMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRT 240
Query: 241 RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDL 300
RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDL
Sbjct: 241 RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDL 300
Query: 301 HYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCR 360
HYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCR
Sbjct: 301 HYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCR 360
Query: 361 APRPDGRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQ 420
APRPDGRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQ
Sbjct: 361 APRPDGRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQ 420
Query: 421 ADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN 465
ADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN
Sbjct: 421 ADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN 465
>gi|190358543 hypothetical protein LOC57654 [Homo sapiens]
Length = 709
Score = 546 bits (1406), Expect = e-155
Identities = 303/439 (69%), Positives = 318/439 (72%), Gaps = 59/439 (13%)
Query: 67 ELFVRSHQFRM----LVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122
E FVRSH L V E L++ D + R+ + +R AV W +
Sbjct: 290 EEFVRSHGLGSHKYTLDVELCSEGLKVQENEDNLALIHAARDTLKLIRNKFLPAVCSWIQ 349
Query: 123 KFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREM 182
+F +G H + +D + AE + K K LD E
Sbjct: 350 RFTR------VGTHGGCLKRAIDLK-------AELELVLRKYKELD------IEPEGGER 390
Query: 183 QQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM 242
++TEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM
Sbjct: 391 RRTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM 450
Query: 243 DEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302
DEEVSDPTSAAAQLRQL L PSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHY
Sbjct: 451 DEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 510
Query: 303 WGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAP 362
WGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAP
Sbjct: 511 WGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAP 570
Query: 363 RPDGRLCERQDRLK------------------------------------EWQDPELMRD 386
RPDGRLCERQDRLK EWQDPELMRD
Sbjct: 571 RPDGRLCERQDRLKCPFHGKIVPRDDEGRPLDPEDRAREQRRQLQKQERPEWQDPELMRD 630
Query: 387 VEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMN 446
VEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMN
Sbjct: 631 VEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMN 690
Query: 447 RMDQKKHEKFSNQFNYALN 465
RMDQKKHEKFSNQFNYALN
Sbjct: 691 RMDQKKHEKFSNQFNYALN 709
Score = 362 bits (928), Expect = e-100
Identities = 183/184 (99%), Positives = 184/184 (100%)
Query: 1 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS
Sbjct: 1 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW
Sbjct: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120
Query: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180
NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER
Sbjct: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180
Query: 181 EMQQ 184
EMQ+
Sbjct: 181 EMQE 184
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 43.1 bits (100), Expect = 5e-04
Identities = 51/196 (26%), Positives = 76/196 (38%), Gaps = 27/196 (13%)
Query: 94 DPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARS 153
+P PLPPP E T+R W E+ E KK L H T + +
Sbjct: 606 EPPPPLPPPPEPISTEPVETSR----WTEEEMEVAKK-GLVEHGRNWAAIAKMVGTKSEA 660
Query: 154 LAERKREEEKQKH-LDKIYQE------RASQAEREMQQTEALGDAEEDEDDEDFVEVPEK 206
+ K++H LD + Q+ R + ER++ Q E++ ++DED E+
Sbjct: 661 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE 720
Query: 207 EGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASP 266
E E + ++P E +PE T R T E+ T A P SP
Sbjct: 721 ENPEDSEVEAVKPS---EDSPENAT----SRGNTEPAVELEPTTETA--------PSTSP 765
Query: 267 SSASPSRALPEPQEAQ 282
S A PS E + +
Sbjct: 766 SLAVPSTKPAEDESVE 781
Score = 35.0 bits (79), Expect = 0.14
Identities = 41/178 (23%), Positives = 69/178 (38%), Gaps = 18/178 (10%)
Query: 123 KFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREM 182
K E YK L + R + + E K EE+K + +K +E+ + E++
Sbjct: 482 KKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEK-EEDKAEKTEKKEEEKKDEEEKDE 540
Query: 183 QQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM 242
++ E+D+ D E E+E P G + A + + TR+
Sbjct: 541 KEDSKENTKEKDKIDGTAEETEEREQATPR---------GRKTANSQGRRKGRI-TRSMT 590
Query: 243 DEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER---ARAPVVPYG 297
+E + +AAA + P PL P P EP E + E A+ +V +G
Sbjct: 591 NEAAAASAAAAAATEEPPPPLPPP----PEPISTEPVETSRWTEEEMEVAKKGLVEHG 644
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 20/158 (12%)
Query: 152 RSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEP 211
R AER+ +E K+K L++ Q ++ + +R++QQ A + + + + ++ K+ +
Sbjct: 442 RRQAERE-QEYKRKQLEE--QRQSERLQRQLQQEHAYLKSLQQQQQQQQLQ---KQQQQQ 495
Query: 212 HIPDHLRPEY----GLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAA---AQLRQLPGPLA 264
+P +P Y G+ A +K R + RTRM+++ + P + + + + P P A
Sbjct: 496 LLPGDRKPLYHYGRGMNPA-DKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQA 554
Query: 265 SPSSASPSRALP------EPQEAQKLAAERARAPVVPY 296
SP P P EPQE + R P+ PY
Sbjct: 555 SPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPY 592
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 20/158 (12%)
Query: 152 RSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEP 211
R AER+ +E K+K L++ Q ++ + +R++QQ A + + + + ++ K+ +
Sbjct: 442 RRQAERE-QEYKRKQLEE--QRQSERLQRQLQQEHAYLKSLQQQQQQQQLQ---KQQQQQ 495
Query: 212 HIPDHLRPEY----GLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAA---AQLRQLPGPLA 264
+P +P Y G+ A +K R + RTRM+++ + P + + + + P P A
Sbjct: 496 LLPGDRKPLYHYGRGMNPA-DKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQA 554
Query: 265 SPSSASPSRALP------EPQEAQKLAAERARAPVVPY 296
SP P P EPQE + R P+ PY
Sbjct: 555 SPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPY 592
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 20/158 (12%)
Query: 152 RSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEP 211
R AER+ +E K+K L++ Q ++ + +R++QQ A + + + + ++ K+ +
Sbjct: 442 RRQAERE-QEYKRKQLEE--QRQSERLQRQLQQEHAYLKSLQQQQQQQQLQ---KQQQQQ 495
Query: 212 HIPDHLRPEY----GLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAA---AQLRQLPGPLA 264
+P +P Y G+ A +K R + RTRM+++ + P + + + + P P A
Sbjct: 496 LLPGDRKPLYHYGRGMNPA-DKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQA 554
Query: 265 SPSSASPSRALP------EPQEAQKLAAERARAPVVPY 296
SP P P EPQE + R P+ PY
Sbjct: 555 SPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPY 592
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/100 (22%), Positives = 52/100 (52%), Gaps = 6/100 (6%)
Query: 142 KKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEED------E 195
KK D ++ + + + K E+++ ++ +E + E E+++ E + + EE+ E
Sbjct: 282 KKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELE 341
Query: 196 DDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRC 235
++E+ +E E+ G E H+P + +EA +++ + C
Sbjct: 342 EEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFISC 381
Score = 34.7 bits (78), Expect = 0.19
Identities = 30/131 (22%), Positives = 58/131 (44%), Gaps = 5/131 (3%)
Query: 158 KREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHL 217
+ EEEK+ ++ Y + A+ ++ E + D EE+ +DE+ EV E E Y + L
Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAE-YVEEGEEEL 335
Query: 218 RPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPE 277
E E E++ + + + P S + + S + +P + +P+
Sbjct: 336 EEE---ELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFISCTFLNPEQIIPK 392
Query: 278 -PQEAQKLAAE 287
PQE+ +A +
Sbjct: 393 VPQESLFMAQD 403
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 40.8 bits (94), Expect = 0.003
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 8/82 (9%)
Query: 139 RHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDE 198
+ KK D + A +++K EEEK+KH ++ +++ QA+R+ Q+ EA +E E+
Sbjct: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ-QEEEAAAQMKEKEESI 128
Query: 199 DFVEVPEKEGYEPHIPDHLRPE 220
+E +E H HLR E
Sbjct: 129 QL----HQEAWERH---HLRKE 143
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 40.8 bits (94), Expect = 0.003
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 8/82 (9%)
Query: 139 RHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDE 198
+ KK D + A +++K EEEK+KH ++ +++ QA+R+ Q+ EA +E E+
Sbjct: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ-QEEEAAAQMKEKEESI 128
Query: 199 DFVEVPEKEGYEPHIPDHLRPE 220
+E +E H HLR E
Sbjct: 129 QL----HQEAWERH---HLRKE 143
>gi|41406057 amyloid beta A4 protein isoform c precursor [Homo
sapiens]
Length = 695
Score = 38.9 bits (89), Expect = 0.010
Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 20/169 (11%)
Query: 168 DKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAP 227
DK+ + + E+++ EA D +ED++D D VE +E Y E A
Sbjct: 223 DKVVEVAEEEEVAEVEEEEA--DDDEDDEDGDEVEEEAEEPY--------------EEAT 266
Query: 228 EKDTVVRCLRTRT--RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLA 285
E+ T + T T ++E V PT+AA+ + L +P + + +E +
Sbjct: 267 ERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAK 326
Query: 286 AERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVN 334
+ V+ + + LP A K K+ QH K +E+E N
Sbjct: 327 HRERMSQVMREWEEAERQAKNLPKADK--KAVIQHFQEKVESLEQEAAN 373
>gi|209915570 amyloid beta A4 protein isoform e precursor [Homo
sapiens]
Length = 639
Score = 38.9 bits (89), Expect = 0.010
Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 20/169 (11%)
Query: 168 DKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAP 227
DK+ + + E+++ EA D +ED++D D VE +E Y E A
Sbjct: 167 DKVVEVAEEEEVAEVEEEEA--DDDEDDEDGDEVEEEAEEPY--------------EEAT 210
Query: 228 EKDTVVRCLRTRT--RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLA 285
E+ T + T T ++E V PT+AA+ + L +P + + +E +
Sbjct: 211 ERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAK 270
Query: 286 AERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVN 334
+ V+ + + LP A K K+ QH K +E+E N
Sbjct: 271 HRERMSQVMREWEEAERQAKNLPKADK--KAVIQHFQEKVESLEQEAAN 317
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 38.9 bits (89), Expect = 0.010
Identities = 53/225 (23%), Positives = 100/225 (44%), Gaps = 24/225 (10%)
Query: 12 LTTSGEPRLNPEKMKELKKICKSSEEQLSRA---YRLLIAQLTQEHAEIRLSAFQIVEEL 68
L +G P + E + SEE+ R +R L A+ ++ AE + + +EE
Sbjct: 194 LDQNGHPGEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEA--AEKRRLEEQ 251
Query: 69 FVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVE--GWNEKFGE 126
+++ + R+ + QE LE + + PP EA + R+ R++E GW + E
Sbjct: 252 RLQALERRLWEENRRQELLE-----EEGEGQEPPLEAERAPREEQQRSLEAPGWED--AE 304
Query: 127 AYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTE 186
++ ++++ ++ R A+ + EE ++ D +ER Q E E + E
Sbjct: 305 RRER--------EERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAE 356
Query: 187 ALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPE-YGLEAAPEKD 230
L +E+E+ E + E+ ++E P+ L G A E+D
Sbjct: 357 EL-KRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRRGAEEED 400
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 38.5 bits (88), Expect = 0.013
Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 7/193 (3%)
Query: 103 REAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEE 162
++ Q+ Q + + E+ E K + + Q+ AR L ++EEE
Sbjct: 597 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 656
Query: 163 KQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYG 222
+++H + + +++ + ER + EA AE+ E + E E+E E + R E
Sbjct: 657 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 716
Query: 223 LEAAPEKDTVVRCLRTRTRMDEEVSDPTSA-AAQLRQLPGPLASPSSASPSRALPEPQ-- 279
+ A ++ R + R + + E+ + A Q QL L + L E Q
Sbjct: 717 RQLAEQER---RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 773
Query: 280 -EAQKLAAERARA 291
E +K A E A A
Sbjct: 774 EEQEKKAKEAAGA 786
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 38.5 bits (88), Expect = 0.013
Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 7/193 (3%)
Query: 103 REAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEE 162
++ Q+ Q + + E+ E K + + Q+ AR L ++EEE
Sbjct: 593 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 652
Query: 163 KQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYG 222
+++H + + +++ + ER + EA AE+ E + E E+E E + R E
Sbjct: 653 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 712
Query: 223 LEAAPEKDTVVRCLRTRTRMDEEVSDPTSA-AAQLRQLPGPLASPSSASPSRALPEPQ-- 279
+ A ++ R + R + + E+ + A Q QL L + L E Q
Sbjct: 713 RQLAEQER---RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
Query: 280 -EAQKLAAERARA 291
E +K A E A A
Sbjct: 770 EEQEKKAKEAAGA 782
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 37.4 bits (85), Expect = 0.029
Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 17/143 (11%)
Query: 104 EAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEK 163
E +RLR+ R E EK E +K+ R KK+ Q+ R E+ +EEE+
Sbjct: 401 EQDERLREKEERMRE--QEKMWEQVEKM-------REEKKMQEQEKKTRDQEEKMQEEER 451
Query: 164 QKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGL 223
+ +K RE ++T + + + +E+ E EKE + +P+ +
Sbjct: 452 IREREK--------KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 224 EAAPEKDTVVRCLRTRTRMDEEV 246
E E++ + + R EE+
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEM 526
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 37.4 bits (85), Expect = 0.029
Identities = 39/150 (26%), Positives = 57/150 (38%), Gaps = 25/150 (16%)
Query: 145 DFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVP 204
D N S E + EEE+++ ++ +E E E + E + EE+E++E E
Sbjct: 877 DLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFE 936
Query: 205 EKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPG--- 261
E+EG L E E E++ + EEV D A G
Sbjct: 937 EEEG-------ELEEEEEEEDEEEEEEL-----------EEVEDLEFGTAGGEVEEGAPP 978
Query: 262 ----PLASPSSASPSRALPEPQEAQKLAAE 287
P A P SP + PEP+ L E
Sbjct: 979 PPTLPPALPPPESPPKVQPEPEPEPGLLLE 1008
Score = 30.0 bits (66), Expect = 4.7
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%)
Query: 160 EEEKQKHLDKIYQERASQAEREMQ-QTEALGDAEEDEDD-----EDFVEVPEKEGYEP 211
EEE + DK+ + AE EM+ +TEA E+++DD DF++ P + P
Sbjct: 1066 EEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPP 1123
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 37.0 bits (84), Expect = 0.038
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 148 DTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKE 207
+ N R + K++E+K+KH K Y+++ S+ R+ D+ E E+F+E P K+
Sbjct: 226 EDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES-----SDSSSKESQEEFLENPWKD 280
Query: 208 GYEPHIPDHL 217
+ P L
Sbjct: 281 RTKAEEPSDL 290
>gi|169168458 PREDICTED: hypothetical protein [Homo sapiens]
Length = 353
Score = 37.0 bits (84), Expect = 0.038
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 7/90 (7%)
Query: 206 KEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLAS 265
+EG H+P +RP + AP ++ R R + PTS R P PLAS
Sbjct: 121 REGSSHHLPRQVRPGPVYKPAPARNH-------RPRGGRGKASPTSFHVSPRAPPAPLAS 173
Query: 266 PSSASPSRALPEPQEAQKLAAERARAPVVP 295
S+ P ++ L++ +A P+ P
Sbjct: 174 MPSSVPKTSIESLGSPSSLSSSQASEPLCP 203
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 37.0 bits (84), Expect = 0.038
Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 5/105 (4%)
Query: 147 QDTNARSLAERKREEEKQKHLDKIYQERASQAERE---MQQTEALGDAEE--DEDDEDFV 201
QD R ER RE+EK ++ QE ERE ++ E + + EE + +E+
Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423
Query: 202 EVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEV 246
E EKE + +P+ + E E++ + + R EE+
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Score = 34.7 bits (78), Expect = 0.19
Identities = 68/368 (18%), Positives = 145/368 (39%), Gaps = 40/368 (10%)
Query: 103 REAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAER--KRE 160
RE ++R+ + + ++ E K+L LR KK+ Q+ + E+ ++E
Sbjct: 265 REQEGKMREQEEK-MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323
Query: 161 EEKQKHLDKIY--QERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLR 218
E+ ++ +K++ +ER + E++M++ E +E+ E + EKE + +R
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-------ERMR 376
Query: 219 PEYGLEAAPEKDTVVRCLRTRTRM--DEEVSDPTSAAAQLRQLPGPLASPSSASPSRALP 276
+ + EK +R R + +EE + +Q + LP
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Query: 277 EPQEA----QKLAAERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEV-EEE 331
E +E +K+ + + W QE + + + W+ ++ E+E
Sbjct: 437 EQKEKLWEQEKMQEQEEKI-----------WEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
Query: 332 VVNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGRLCERQDRLKE----WQDPELMRDV 387
+ E +R + + E R D RL E+++R++E WQ E MR+
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEE------RMWEQDERLREKEERMREQKKMWQQEEKMREE 539
Query: 388 EAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMNR 447
+ Q+ + K R ++R ++ + + R + + + +R M
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599
Query: 448 MDQKKHEK 455
++K E+
Sbjct: 600 QEEKMQEQ 607
>gi|239742749 PREDICTED: hypothetical protein XP_002342626 [Homo
sapiens]
Length = 277
Score = 37.0 bits (84), Expect = 0.038
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 7/90 (7%)
Query: 206 KEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLAS 265
+EG H+P +RP + AP ++ R R + PTS R P PLAS
Sbjct: 121 REGSSHHLPRQVRPGPVYKPAPARNH-------RPRGGRGKASPTSFHVSPRAPPAPLAS 173
Query: 266 PSSASPSRALPEPQEAQKLAAERARAPVVP 295
S+ P ++ L++ +A P+ P
Sbjct: 174 MPSSVPKTSIESLGSPSSLSSSQASEPLCP 203
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 37.0 bits (84), Expect = 0.038
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 141 NKKVDFQDTNARSLAER-----KREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDE 195
N+ +D +D + + E + EEEK K D+ +E + + E ++ E + EEDE
Sbjct: 497 NENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEE-DEDDEEAEEEEEEEEEEEDE 555
Query: 196 DDEDFVEVPEKEGYEPHIPDHLR 218
DD+D E E E Y P + +R
Sbjct: 556 DDDDNNEEEEFECYPPGMKVQVR 578
Score = 30.4 bits (67), Expect = 3.6
Identities = 48/252 (19%), Positives = 97/252 (38%), Gaps = 17/252 (6%)
Query: 6 SKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIV 65
++L E+ ++S E+ E +K SSEE+ I +E ++ +
Sbjct: 267 TELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEE------IEPFPEERENFLQQLYKFM 320
Query: 66 EELFVRSHQFRMLVVSNFQEFLELTL-----GTDPAQPLPPPREAAQRLRQATTRAVEGW 120
E+ ++ +L N F L G D + ++ Q L + G+
Sbjct: 321 EDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGY 380
Query: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180
N K AYKK G+ + ++FQ + ++ +E + K+ +E ++ +
Sbjct: 381 NVKC--AYKKYLYGFEEYCRSANIEFQMALPEKVVNKQCKECENVKEIKVKEENETEIKE 438
Query: 181 EMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI--PDHLRPEYGLEAAPEKDTVVRCLRT 238
+ E E++ ED E+ KE +P + +L + EK+ ++
Sbjct: 439 IKMEEERNIIPREEKPIED--EIERKENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPED 496
Query: 239 RTRMDEEVSDPT 250
+D++ D T
Sbjct: 497 NENLDDKDDDTT 508
>gi|231570186 zinc finger CCCH-type containing 14 isoform 6 [Homo
sapiens]
Length = 730
Score = 36.6 bits (83), Expect = 0.050
Identities = 40/211 (18%), Positives = 80/211 (37%), Gaps = 32/211 (15%)
Query: 158 KREEEKQKHLDKIYQERASQAEREMQQTEALG-DAEEDEDDEDF----------VEVPEK 206
+ EK D+ +++R + + + D EE+E+D+D+ V VP K
Sbjct: 278 RNNSEKMSMEDENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDYGSRTGSISSSVSVPAK 337
Query: 207 EGYEPHIPDHLRPEYGL------------------EAAPEKDTVVRCLRTRTRMDEEVSD 248
P +P + L P+K T+ RTRT +E +++
Sbjct: 338 PERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVPQKQTLPVAPRTRTSQEELLAE 397
Query: 249 PTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELP 308
++ ++ P+ + S + + ++L +R + P + Q+
Sbjct: 398 VVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQRQLL---SRLQIDPVMAETLQMSQDYY 454
Query: 309 TAGKIVKSDSQHRFWKPSEVEEEVVNADISE 339
+V +D++ K ++ EEVV A E
Sbjct: 455 DMESMVHADTRSFILKKPKLSEEVVVAPNQE 485
>gi|231570121 zinc finger CCCH-type containing 14 isoform 5 [Homo
sapiens]
Length = 735
Score = 36.6 bits (83), Expect = 0.050
Identities = 40/211 (18%), Positives = 80/211 (37%), Gaps = 32/211 (15%)
Query: 158 KREEEKQKHLDKIYQERASQAEREMQQTEALG-DAEEDEDDEDF----------VEVPEK 206
+ EK D+ +++R + + + D EE+E+D+D+ V VP K
Sbjct: 278 RNNSEKMSMEDENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDYGSRTGSISSSVSVPAK 337
Query: 207 EGYEPHIPDHLRPEYGL------------------EAAPEKDTVVRCLRTRTRMDEEVSD 248
P +P + L P+K T+ RTRT +E +++
Sbjct: 338 PERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVPQKQTLPVAPRTRTSQEELLAE 397
Query: 249 PTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELP 308
++ ++ P+ + S + + ++L +R + P + Q+
Sbjct: 398 VVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQRQLL---SRLQIDPVMAETLQMSQDYY 454
Query: 309 TAGKIVKSDSQHRFWKPSEVEEEVVNADISE 339
+V +D++ K ++ EEVV A E
Sbjct: 455 DMESMVHADTRSFILKKPKLSEEVVVAPNQE 485
>gi|40804742 zinc finger CCCH-type containing 14 isoform 1 [Homo
sapiens]
Length = 736
Score = 36.6 bits (83), Expect = 0.050
Identities = 40/211 (18%), Positives = 80/211 (37%), Gaps = 32/211 (15%)
Query: 158 KREEEKQKHLDKIYQERASQAEREMQQTEALG-DAEEDEDDEDF----------VEVPEK 206
+ EK D+ +++R + + + D EE+E+D+D+ V VP K
Sbjct: 278 RNNSEKMSMEDENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDYGSRTGSISSSVSVPAK 337
Query: 207 EGYEPHIPDHLRPEYGL------------------EAAPEKDTVVRCLRTRTRMDEEVSD 248
P +P + L P+K T+ RTRT +E +++
Sbjct: 338 PERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVPQKQTLPVAPRTRTSQEELLAE 397
Query: 249 PTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELP 308
++ ++ P+ + S + + ++L +R + P + Q+
Sbjct: 398 VVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQRQLL---SRLQIDPVMAETLQMSQDYY 454
Query: 309 TAGKIVKSDSQHRFWKPSEVEEEVVNADISE 339
+V +D++ K ++ EEVV A E
Sbjct: 455 DMESMVHADTRSFILKKPKLSEEVVVAPNQE 485
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 36.6 bits (83), Expect = 0.050
Identities = 48/216 (22%), Positives = 89/216 (41%), Gaps = 21/216 (9%)
Query: 5 LSKLVEELTTSGEPRLNPEKM----KELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60
+ +L+++ E ++NPEK+ K+L+ I ++ RA R ++ + +
Sbjct: 427 VQQLLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVYLMKDKE 486
Query: 61 AFQIVEELFVRSHQFRM-LVVSNFQEFLELTLGTDPAQPL---PPPREAAQRLRQATTRA 116
F V +L + + + L V+ FL+ + P + L + R T
Sbjct: 487 VFD-VSKLPIPEYALSLGLAVAPRVRFLQ-KMQKQPTKELVRSQADKVIEPRAPSLTNDE 544
Query: 117 VEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERAS 176
VE + F E L G L + DT E + +EE+ + +K+ + + S
Sbjct: 545 VEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEEME--EKLAKAKGS 602
Query: 177 QAEREMQQTEALG---------DAEEDEDDEDFVEV 203
QA +EA D +E+E+D DF++V
Sbjct: 603 QAPSLPNTSEAQKIKEVPTQFLDRDEEEEDADFLKV 638
Score = 31.6 bits (70), Expect = 1.6
Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 14/67 (20%)
Query: 156 ERKREEEKQKHLDKIYQERASQAEREMQQT------EALGDAEEDEDDEDFVEVPEKEGY 209
E R++ K KH +K +ER ++ E +Q EA D +D+DD+D +G+
Sbjct: 738 EEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWSDDDDDDD-------DGF 790
Query: 210 EPH-IPD 215
+P +PD
Sbjct: 791 DPSTLPD 797
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 36.6 bits (83), Expect = 0.050
Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%)
Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83
K++E +++ + +E++ +R QL QE A+ RL A + ++H F V
Sbjct: 2017 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2061
Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143
++ L+ TL + + L R A+ R+A A E + EA + R +
Sbjct: 2062 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200
+ Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2173
Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249
E + +K E + DH + E K R R++++EE+
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233
Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302
+L +L + + + A + R L E E K AE A L
Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2285
Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361
QE ++ + D +Q R ++E++ + L++ + E Q R
Sbjct: 2286 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2345
Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416
+ D +L E + + E R +E + + R + R + R
Sbjct: 2346 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405
Query: 417 LKAQADTARARIGRKVFA 434
+ QA+ ++ R A
Sbjct: 2406 FRKQAEEIGEKLHRTELA 2423
Score = 33.5 bits (75), Expect = 0.42
Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%)
Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61
++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S
Sbjct: 1396 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1447
Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121
+I EE+ V Q EL A+ + AQ + R V+ +
Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1507
Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177
++ +A +LA R + + R+L R + EE ++ L + ERA Q
Sbjct: 1508 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1562
Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234
+ ++ + +AE F E E+ E H+ E A ++ R
Sbjct: 1563 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1622
Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291
R E + A +LR +A S + + A + +EA++ A R +A
Sbjct: 1623 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1679
Score = 33.1 bits (74), Expect = 0.55
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213
LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++
Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1421
Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272
LR E + R+R R++EE+ A RQ G +
Sbjct: 1422 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1478
Query: 273 RALPEPQEAQKLAAE 287
RA E EAQK A+
Sbjct: 1479 RARAEEAEAQKRQAQ 1493
Score = 32.7 bits (73), Expect = 0.72
Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%)
Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62
Q+ + +EEL E + E+++ + + L A R A+L + A
Sbjct: 1532 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1590
Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122
Q+ RS Q + V+ +E A+ + A+R R+ R +E W
Sbjct: 1591 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1636
Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174
K EA + LR ++V Q + A++ AE+++EE +++ + Q
Sbjct: 1637 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1688
Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228
++ E E Q+ A G A+ E E E + E + + L R + AA +
Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1748
Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288
K + + R + EV + A A+ S S S R E ++LA E
Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1803
Query: 289 AR 290
AR
Sbjct: 1804 AR 1805
Score = 30.8 bits (68), Expect = 2.7
Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%)
Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60
+L +L EE + R EKM + K +L LL Q L QE A ++
Sbjct: 2292 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2349
Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112
Q+ ++L + F+ + + Q LE++ + ++ E AQR R+
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409
Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171
E + +K+ L ++ D R ++AE +RE+EK + K+
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469
Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202
Q ++ Q E+ +Q+T+AL + E D E F+E
Sbjct: 2470 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2510
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 36.6 bits (83), Expect = 0.050
Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%)
Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83
K++E +++ + +E++ +R QL QE A+ RL A + ++H F V
Sbjct: 2021 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2065
Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143
++ L+ TL + + L R A+ R+A A E + EA + R +
Sbjct: 2066 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2124
Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200
+ Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F
Sbjct: 2125 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2177
Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249
E + +K E + DH + E K R R++++EE+
Sbjct: 2178 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2237
Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302
+L +L + + + A + R L E E K AE A L
Sbjct: 2238 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2289
Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361
QE ++ + D +Q R ++E++ + L++ + E Q R
Sbjct: 2290 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2349
Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416
+ D +L E + + E R +E + + R + R + R
Sbjct: 2350 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2409
Query: 417 LKAQADTARARIGRKVFA 434
+ QA+ ++ R A
Sbjct: 2410 FRKQAEEIGEKLHRTELA 2427
Score = 33.5 bits (75), Expect = 0.42
Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%)
Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61
++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S
Sbjct: 1400 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1451
Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121
+I EE+ V Q EL A+ + AQ + R V+ +
Sbjct: 1452 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1511
Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177
++ +A +LA R + + R+L R + EE ++ L + ERA Q
Sbjct: 1512 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1566
Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234
+ ++ + +AE F E E+ E H+ E A ++ R
Sbjct: 1567 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1626
Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291
R E + A +LR +A S + + A + +EA++ A R +A
Sbjct: 1627 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1683
Score = 33.1 bits (74), Expect = 0.55
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213
LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++
Sbjct: 1366 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1425
Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272
LR E + R+R R++EE+ A RQ G +
Sbjct: 1426 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1482
Query: 273 RALPEPQEAQKLAAE 287
RA E EAQK A+
Sbjct: 1483 RARAEEAEAQKRQAQ 1497
Score = 32.7 bits (73), Expect = 0.72
Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%)
Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62
Q+ + +EEL E + E+++ + + L A R A+L + A
Sbjct: 1536 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1594
Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122
Q+ RS Q + V+ +E A+ + A+R R+ R +E W
Sbjct: 1595 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1640
Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174
K EA + LR ++V Q + A++ AE+++EE +++ + Q
Sbjct: 1641 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1692
Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228
++ E E Q+ A G A+ E E E + E + + L R + AA +
Sbjct: 1693 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1752
Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288
K + + R + EV + A A+ S S S R E ++LA E
Sbjct: 1753 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1807
Query: 289 AR 290
AR
Sbjct: 1808 AR 1809
Score = 30.8 bits (68), Expect = 2.7
Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%)
Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60
+L +L EE + R EKM + K +L LL Q L QE A ++
Sbjct: 2296 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2353
Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112
Q+ ++L + F+ + + Q LE++ + ++ E AQR R+
Sbjct: 2354 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2413
Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171
E + +K+ L ++ D R ++AE +RE+EK + K+
Sbjct: 2414 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2473
Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202
Q ++ Q E+ +Q+T+AL + E D E F+E
Sbjct: 2474 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2514
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 36.6 bits (83), Expect = 0.050
Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%)
Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83
K++E +++ + +E++ +R QL QE A+ RL A + ++H F V
Sbjct: 2017 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2061
Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143
++ L+ TL + + L R A+ R+A A E + EA + R +
Sbjct: 2062 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200
+ Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2173
Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249
E + +K E + DH + E K R R++++EE+
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233
Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302
+L +L + + + A + R L E E K AE A L
Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2285
Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361
QE ++ + D +Q R ++E++ + L++ + E Q R
Sbjct: 2286 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2345
Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416
+ D +L E + + E R +E + + R + R + R
Sbjct: 2346 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405
Query: 417 LKAQADTARARIGRKVFA 434
+ QA+ ++ R A
Sbjct: 2406 FRKQAEEIGEKLHRTELA 2423
Score = 33.5 bits (75), Expect = 0.42
Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%)
Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61
++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S
Sbjct: 1396 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1447
Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121
+I EE+ V Q EL A+ + AQ + R V+ +
Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1507
Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177
++ +A +LA R + + R+L R + EE ++ L + ERA Q
Sbjct: 1508 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1562
Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234
+ ++ + +AE F E E+ E H+ E A ++ R
Sbjct: 1563 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1622
Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291
R E + A +LR +A S + + A + +EA++ A R +A
Sbjct: 1623 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1679
Score = 33.1 bits (74), Expect = 0.55
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213
LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++
Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1421
Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272
LR E + R+R R++EE+ A RQ G +
Sbjct: 1422 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1478
Query: 273 RALPEPQEAQKLAAE 287
RA E EAQK A+
Sbjct: 1479 RARAEEAEAQKRQAQ 1493
Score = 32.7 bits (73), Expect = 0.72
Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%)
Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62
Q+ + +EEL E + E+++ + + L A R A+L + A
Sbjct: 1532 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1590
Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122
Q+ RS Q + V+ +E A+ + A+R R+ R +E W
Sbjct: 1591 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1636
Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174
K EA + LR ++V Q + A++ AE+++EE +++ + Q
Sbjct: 1637 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1688
Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228
++ E E Q+ A G A+ E E E + E + + L R + AA +
Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1748
Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288
K + + R + EV + A A+ S S S R E ++LA E
Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1803
Query: 289 AR 290
AR
Sbjct: 1804 AR 1805
Score = 30.8 bits (68), Expect = 2.7
Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%)
Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60
+L +L EE + R EKM + K +L LL Q L QE A ++
Sbjct: 2292 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2349
Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112
Q+ ++L + F+ + + Q LE++ + ++ E AQR R+
Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409
Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171
E + +K+ L ++ D R ++AE +RE+EK + K+
Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469
Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202
Q ++ Q E+ +Q+T+AL + E D E F+E
Sbjct: 2470 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2510
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 36.6 bits (83), Expect = 0.050
Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%)
Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83
K++E +++ + +E++ +R QL QE A+ RL A + ++H F V
Sbjct: 1985 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2029
Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143
++ L+ TL + + L R A+ R+A A E + EA + R +
Sbjct: 2030 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2088
Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200
+ Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F
Sbjct: 2089 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2141
Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249
E + +K E + DH + E K R R++++EE+
Sbjct: 2142 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2201
Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302
+L +L + + + A + R L E E K AE A L
Sbjct: 2202 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2253
Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361
QE ++ + D +Q R ++E++ + L++ + E Q R
Sbjct: 2254 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2313
Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416
+ D +L E + + E R +E + + R + R + R
Sbjct: 2314 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2373
Query: 417 LKAQADTARARIGRKVFA 434
+ QA+ ++ R A
Sbjct: 2374 FRKQAEEIGEKLHRTELA 2391
Score = 33.5 bits (75), Expect = 0.42
Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%)
Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61
++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S
Sbjct: 1364 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1415
Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121
+I EE+ V Q EL A+ + AQ + R V+ +
Sbjct: 1416 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1475
Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177
++ +A +LA R + + R+L R + EE ++ L + ERA Q
Sbjct: 1476 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1530
Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234
+ ++ + +AE F E E+ E H+ E A ++ R
Sbjct: 1531 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1590
Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291
R E + A +LR +A S + + A + +EA++ A R +A
Sbjct: 1591 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1647
Score = 33.1 bits (74), Expect = 0.55
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213
LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++
Sbjct: 1330 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1389
Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272
LR E + R+R R++EE+ A RQ G +
Sbjct: 1390 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1446
Query: 273 RALPEPQEAQKLAAE 287
RA E EAQK A+
Sbjct: 1447 RARAEEAEAQKRQAQ 1461
Score = 32.7 bits (73), Expect = 0.72
Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%)
Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62
Q+ + +EEL E + E+++ + + L A R A+L + A
Sbjct: 1500 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1558
Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122
Q+ RS Q + V+ +E A+ + A+R R+ R +E W
Sbjct: 1559 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1604
Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174
K EA + LR ++V Q + A++ AE+++EE +++ + Q
Sbjct: 1605 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1656
Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228
++ E E Q+ A G A+ E E E + E + + L R + AA +
Sbjct: 1657 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1716
Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288
K + + R + EV + A A+ S S S R E ++LA E
Sbjct: 1717 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1771
Query: 289 AR 290
AR
Sbjct: 1772 AR 1773
Score = 30.8 bits (68), Expect = 2.7
Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%)
Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60
+L +L EE + R EKM + K +L LL Q L QE A ++
Sbjct: 2260 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2317
Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112
Q+ ++L + F+ + + Q LE++ + ++ E AQR R+
Sbjct: 2318 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2377
Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171
E + +K+ L ++ D R ++AE +RE+EK + K+
Sbjct: 2378 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2437
Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202
Q ++ Q E+ +Q+T+AL + E D E F+E
Sbjct: 2438 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2478
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 36.6 bits (83), Expect = 0.050
Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%)
Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83
K++E +++ + +E++ +R QL QE A+ RL A + ++H F V
Sbjct: 2154 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2198
Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143
++ L+ TL + + L R A+ R+A A E + EA + R +
Sbjct: 2199 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2257
Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200
+ Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F
Sbjct: 2258 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2310
Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249
E + +K E + DH + E K R R++++EE+
Sbjct: 2311 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2370
Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302
+L +L + + + A + R L E E K AE A L
Sbjct: 2371 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2422
Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361
QE ++ + D +Q R ++E++ + L++ + E Q R
Sbjct: 2423 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2482
Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416
+ D +L E + + E R +E + + R + R + R
Sbjct: 2483 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2542
Query: 417 LKAQADTARARIGRKVFA 434
+ QA+ ++ R A
Sbjct: 2543 FRKQAEEIGEKLHRTELA 2560
Score = 33.5 bits (75), Expect = 0.42
Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%)
Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61
++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S
Sbjct: 1533 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1584
Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121
+I EE+ V Q EL A+ + AQ + R V+ +
Sbjct: 1585 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1644
Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177
++ +A +LA R + + R+L R + EE ++ L + ERA Q
Sbjct: 1645 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1699
Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234
+ ++ + +AE F E E+ E H+ E A ++ R
Sbjct: 1700 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1759
Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291
R E + A +LR +A S + + A + +EA++ A R +A
Sbjct: 1760 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1816
Score = 33.1 bits (74), Expect = 0.55
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%)
Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213
LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++
Sbjct: 1499 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1558
Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272
LR E + R+R R++EE+ A RQ G +
Sbjct: 1559 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1615
Query: 273 RALPEPQEAQKLAAE 287
RA E EAQK A+
Sbjct: 1616 RARAEEAEAQKRQAQ 1630
Score = 32.7 bits (73), Expect = 0.72
Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%)
Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62
Q+ + +EEL E + E+++ + + L A R A+L + A
Sbjct: 1669 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1727
Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122
Q+ RS Q + V+ +E A+ + A+R R+ R +E W
Sbjct: 1728 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1773
Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174
K EA + LR ++V Q + A++ AE+++EE +++ + Q
Sbjct: 1774 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1825
Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228
++ E E Q+ A G A+ E E E + E + + L R + AA +
Sbjct: 1826 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1885
Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288
K + + R + EV + A A+ S S S R E ++LA E
Sbjct: 1886 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1940
Query: 289 AR 290
AR
Sbjct: 1941 AR 1942
Score = 30.8 bits (68), Expect = 2.7
Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%)
Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60
+L +L EE + R EKM + K +L LL Q L QE A ++
Sbjct: 2429 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2486
Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112
Q+ ++L + F+ + + Q LE++ + ++ E AQR R+
Sbjct: 2487 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2546
Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171
E + +K+ L ++ D R ++AE +RE+EK + K+
Sbjct: 2547 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2606
Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202
Q ++ Q E+ +Q+T+AL + E D E F+E
Sbjct: 2607 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2647
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,607,689
Number of Sequences: 37866
Number of extensions: 937897
Number of successful extensions: 8160
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 332
Number of HSP's that attempted gapping in prelim test: 6687
Number of HSP's gapped (non-prelim): 1399
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.