BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239748340 PREDICTED: hypothetical protein XP_002346633 [Homo sapiens] (465 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239748340 PREDICTED: hypothetical protein XP_002346633 [Homo ... 931 0.0 gi|190358543 hypothetical protein LOC57654 [Homo sapiens] 546 e-155 gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 43 5e-04 gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 42 0.001 gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 42 0.001 gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 42 0.001 gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 42 0.001 gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 41 0.003 gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 41 0.003 gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa... 39 0.010 gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s... 39 0.010 gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 39 0.010 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 39 0.013 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 39 0.013 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.029 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 37 0.029 gi|168229156 NFKB activating protein [Homo sapiens] 37 0.038 gi|169168458 PREDICTED: hypothetical protein [Homo sapiens] 37 0.038 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.038 gi|239742749 PREDICTED: hypothetical protein XP_002342626 [Homo ... 37 0.038 gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 37 0.038 gi|231570186 zinc finger CCCH-type containing 14 isoform 6 [Homo... 37 0.050 gi|231570121 zinc finger CCCH-type containing 14 isoform 5 [Homo... 37 0.050 gi|40804742 zinc finger CCCH-type containing 14 isoform 1 [Homo ... 37 0.050 gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 37 0.050 gi|41322923 plectin 1 isoform 11 [Homo sapiens] 37 0.050 gi|41322914 plectin 1 isoform 10 [Homo sapiens] 37 0.050 gi|41322919 plectin 1 isoform 8 [Homo sapiens] 37 0.050 gi|41322910 plectin 1 isoform 7 [Homo sapiens] 37 0.050 gi|41322916 plectin 1 isoform 6 [Homo sapiens] 37 0.050 >gi|239748340 PREDICTED: hypothetical protein XP_002346633 [Homo sapiens] Length = 465 Score = 931 bits (2406), Expect = 0.0 Identities = 465/465 (100%), Positives = 465/465 (100%) Query: 1 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS Sbjct: 1 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60 Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW Sbjct: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120 Query: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER Sbjct: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180 Query: 181 EMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRT 240 EMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRT Sbjct: 181 EMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRT 240 Query: 241 RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDL 300 RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDL Sbjct: 241 RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDL 300 Query: 301 HYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCR 360 HYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCR Sbjct: 301 HYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCR 360 Query: 361 APRPDGRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQ 420 APRPDGRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQ Sbjct: 361 APRPDGRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQ 420 Query: 421 ADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN 465 ADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN Sbjct: 421 ADTARARIGRKVFAKAAVRRVVAAMNRMDQKKHEKFSNQFNYALN 465 >gi|190358543 hypothetical protein LOC57654 [Homo sapiens] Length = 709 Score = 546 bits (1406), Expect = e-155 Identities = 303/439 (69%), Positives = 318/439 (72%), Gaps = 59/439 (13%) Query: 67 ELFVRSHQFRM----LVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122 E FVRSH L V E L++ D + R+ + +R AV W + Sbjct: 290 EEFVRSHGLGSHKYTLDVELCSEGLKVQENEDNLALIHAARDTLKLIRNKFLPAVCSWIQ 349 Query: 123 KFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREM 182 +F +G H + +D + AE + K K LD E Sbjct: 350 RFTR------VGTHGGCLKRAIDLK-------AELELVLRKYKELD------IEPEGGER 390 Query: 183 QQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM 242 ++TEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM Sbjct: 391 RRTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM 450 Query: 243 DEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302 DEEVSDPTSAAAQLRQL L PSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHY Sbjct: 451 DEEVSDPTSAAAQLRQLRDHLPPPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 510 Query: 303 WGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAP 362 WGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAP Sbjct: 511 WGQELPTAGKIVKSDSQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRAP 570 Query: 363 RPDGRLCERQDRLK------------------------------------EWQDPELMRD 386 RPDGRLCERQDRLK EWQDPELMRD Sbjct: 571 RPDGRLCERQDRLKCPFHGKIVPRDDEGRPLDPEDRAREQRRQLQKQERPEWQDPELMRD 630 Query: 387 VEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMN 446 VEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMN Sbjct: 631 VEAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMN 690 Query: 447 RMDQKKHEKFSNQFNYALN 465 RMDQKKHEKFSNQFNYALN Sbjct: 691 RMDQKKHEKFSNQFNYALN 709 Score = 362 bits (928), Expect = e-100 Identities = 183/184 (99%), Positives = 184/184 (100%) Query: 1 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS Sbjct: 1 MDQKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60 Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW Sbjct: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGW 120 Query: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER Sbjct: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180 Query: 181 EMQQ 184 EMQ+ Sbjct: 181 EMQE 184 >gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] Length = 2440 Score = 43.1 bits (100), Expect = 5e-04 Identities = 51/196 (26%), Positives = 76/196 (38%), Gaps = 27/196 (13%) Query: 94 DPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARS 153 +P PLPPP E T+R W E+ E KK L H T + + Sbjct: 606 EPPPPLPPPPEPISTEPVETSR----WTEEEMEVAKK-GLVEHGRNWAAIAKMVGTKSEA 660 Query: 154 LAERKREEEKQKH-LDKIYQE------RASQAEREMQQTEALGDAEEDEDDEDFVEVPEK 206 + K++H LD + Q+ R + ER++ Q E++ ++DED E+ Sbjct: 661 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE 720 Query: 207 EGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASP 266 E E + ++P E +PE T R T E+ T A P SP Sbjct: 721 ENPEDSEVEAVKPS---EDSPENAT----SRGNTEPAVELEPTTETA--------PSTSP 765 Query: 267 SSASPSRALPEPQEAQ 282 S A PS E + + Sbjct: 766 SLAVPSTKPAEDESVE 781 Score = 35.0 bits (79), Expect = 0.14 Identities = 41/178 (23%), Positives = 69/178 (38%), Gaps = 18/178 (10%) Query: 123 KFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREM 182 K E YK L + R + + E K EE+K + +K +E+ + E++ Sbjct: 482 KKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEK-EEDKAEKTEKKEEEKKDEEEKDE 540 Query: 183 QQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRM 242 ++ E+D+ D E E+E P G + A + + TR+ Sbjct: 541 KEDSKENTKEKDKIDGTAEETEEREQATPR---------GRKTANSQGRRKGRI-TRSMT 590 Query: 243 DEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER---ARAPVVPYG 297 +E + +AAA + P PL P P EP E + E A+ +V +G Sbjct: 591 NEAAAASAAAAAATEEPPPPLPPP----PEPISTEPVETSRWTEEEMEVAKKGLVEHG 644 >gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] Length = 1303 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Query: 152 RSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEP 211 R AER+ +E K+K L++ Q ++ + +R++QQ A + + + + ++ K+ + Sbjct: 442 RRQAERE-QEYKRKQLEE--QRQSERLQRQLQQEHAYLKSLQQQQQQQQLQ---KQQQQQ 495 Query: 212 HIPDHLRPEY----GLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAA---AQLRQLPGPLA 264 +P +P Y G+ A +K R + RTRM+++ + P + + + + P P A Sbjct: 496 LLPGDRKPLYHYGRGMNPA-DKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQA 554 Query: 265 SPSSASPSRALP------EPQEAQKLAAERARAPVVPY 296 SP P P EPQE + R P+ PY Sbjct: 555 SPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPY 592 >gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] Length = 1332 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Query: 152 RSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEP 211 R AER+ +E K+K L++ Q ++ + +R++QQ A + + + + ++ K+ + Sbjct: 442 RRQAERE-QEYKRKQLEE--QRQSERLQRQLQQEHAYLKSLQQQQQQQQLQ---KQQQQQ 495 Query: 212 HIPDHLRPEY----GLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAA---AQLRQLPGPLA 264 +P +P Y G+ A +K R + RTRM+++ + P + + + + P P A Sbjct: 496 LLPGDRKPLYHYGRGMNPA-DKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQA 554 Query: 265 SPSSASPSRALP------EPQEAQKLAAERARAPVVPY 296 SP P P EPQE + R P+ PY Sbjct: 555 SPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPY 592 >gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] Length = 1295 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Query: 152 RSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEP 211 R AER+ +E K+K L++ Q ++ + +R++QQ A + + + + ++ K+ + Sbjct: 442 RRQAERE-QEYKRKQLEE--QRQSERLQRQLQQEHAYLKSLQQQQQQQQLQ---KQQQQQ 495 Query: 212 HIPDHLRPEY----GLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAA---AQLRQLPGPLA 264 +P +P Y G+ A +K R + RTRM+++ + P + + + + P P A Sbjct: 496 LLPGDRKPLYHYGRGMNPA-DKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQA 554 Query: 265 SPSSASPSRALP------EPQEAQKLAAERARAPVVPY 296 SP P P EPQE + R P+ PY Sbjct: 555 SPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPY 592 >gi|22749303 hypothetical protein LOC196477 [Homo sapiens] Length = 406 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/100 (22%), Positives = 52/100 (52%), Gaps = 6/100 (6%) Query: 142 KKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEED------E 195 KK D ++ + + + K E+++ ++ +E + E E+++ E + + EE+ E Sbjct: 282 KKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELE 341 Query: 196 DDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRC 235 ++E+ +E E+ G E H+P + +EA +++ + C Sbjct: 342 EEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFISC 381 Score = 34.7 bits (78), Expect = 0.19 Identities = 30/131 (22%), Positives = 58/131 (44%), Gaps = 5/131 (3%) Query: 158 KREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHL 217 + EEEK+ ++ Y + A+ ++ E + D EE+ +DE+ EV E E Y + L Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAE-YVEEGEEEL 335 Query: 218 RPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPE 277 E E E++ + + + P S + + S + +P + +P+ Sbjct: 336 EEE---ELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFISCTFLNPEQIIPK 392 Query: 278 -PQEAQKLAAE 287 PQE+ +A + Sbjct: 393 VPQESLFMAQD 403 >gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 40.8 bits (94), Expect = 0.003 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 8/82 (9%) Query: 139 RHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDE 198 + KK D + A +++K EEEK+KH ++ +++ QA+R+ Q+ EA +E E+ Sbjct: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ-QEEEAAAQMKEKEESI 128 Query: 199 DFVEVPEKEGYEPHIPDHLRPE 220 +E +E H HLR E Sbjct: 129 QL----HQEAWERH---HLRKE 143 >gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 40.8 bits (94), Expect = 0.003 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 8/82 (9%) Query: 139 RHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDE 198 + KK D + A +++K EEEK+KH ++ +++ QA+R+ Q+ EA +E E+ Sbjct: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ-QEEEAAAQMKEKEESI 128 Query: 199 DFVEVPEKEGYEPHIPDHLRPE 220 +E +E H HLR E Sbjct: 129 QL----HQEAWERH---HLRKE 143 >gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sapiens] Length = 695 Score = 38.9 bits (89), Expect = 0.010 Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 20/169 (11%) Query: 168 DKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAP 227 DK+ + + E+++ EA D +ED++D D VE +E Y E A Sbjct: 223 DKVVEVAEEEEVAEVEEEEA--DDDEDDEDGDEVEEEAEEPY--------------EEAT 266 Query: 228 EKDTVVRCLRTRT--RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLA 285 E+ T + T T ++E V PT+AA+ + L +P + + +E + Sbjct: 267 ERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAK 326 Query: 286 AERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVN 334 + V+ + + LP A K K+ QH K +E+E N Sbjct: 327 HRERMSQVMREWEEAERQAKNLPKADK--KAVIQHFQEKVESLEQEAAN 373 >gi|209915570 amyloid beta A4 protein isoform e precursor [Homo sapiens] Length = 639 Score = 38.9 bits (89), Expect = 0.010 Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 20/169 (11%) Query: 168 DKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGLEAAP 227 DK+ + + E+++ EA D +ED++D D VE +E Y E A Sbjct: 167 DKVVEVAEEEEVAEVEEEEA--DDDEDDEDGDEVEEEAEEPY--------------EEAT 210 Query: 228 EKDTVVRCLRTRT--RMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLA 285 E+ T + T T ++E V PT+AA+ + L +P + + +E + Sbjct: 211 ERTTSIATTTTTTTESVEEVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAK 270 Query: 286 AERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEVEEEVVN 334 + V+ + + LP A K K+ QH K +E+E N Sbjct: 271 HRERMSQVMREWEEAERQAKNLPKADK--KAVIQHFQEKVESLEQEAAN 317 >gi|148806928 hypothetical protein LOC57482 [Homo sapiens] Length = 1233 Score = 38.9 bits (89), Expect = 0.010 Identities = 53/225 (23%), Positives = 100/225 (44%), Gaps = 24/225 (10%) Query: 12 LTTSGEPRLNPEKMKELKKICKSSEEQLSRA---YRLLIAQLTQEHAEIRLSAFQIVEEL 68 L +G P + E + SEE+ R +R L A+ ++ AE + + +EE Sbjct: 194 LDQNGHPGEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEA--AEKRRLEEQ 251 Query: 69 FVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVE--GWNEKFGE 126 +++ + R+ + QE LE + + PP EA + R+ R++E GW + E Sbjct: 252 RLQALERRLWEENRRQELLE-----EEGEGQEPPLEAERAPREEQQRSLEAPGWED--AE 304 Query: 127 AYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTE 186 ++ ++++ ++ R A+ + EE ++ D +ER Q E E + E Sbjct: 305 RRER--------EERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAE 356 Query: 187 ALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPE-YGLEAAPEKD 230 L +E+E+ E + E+ ++E P+ L G A E+D Sbjct: 357 EL-KRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRRGAEEED 400 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 38.5 bits (88), Expect = 0.013 Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 7/193 (3%) Query: 103 REAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEE 162 ++ Q+ Q + + E+ E K + + Q+ AR L ++EEE Sbjct: 597 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 656 Query: 163 KQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYG 222 +++H + + +++ + ER + EA AE+ E + E E+E E + R E Sbjct: 657 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 716 Query: 223 LEAAPEKDTVVRCLRTRTRMDEEVSDPTSA-AAQLRQLPGPLASPSSASPSRALPEPQ-- 279 + A ++ R + R + + E+ + A Q QL L + L E Q Sbjct: 717 RQLAEQER---RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 773 Query: 280 -EAQKLAAERARA 291 E +K A E A A Sbjct: 774 EEQEKKAKEAAGA 786 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 38.5 bits (88), Expect = 0.013 Identities = 44/193 (22%), Positives = 79/193 (40%), Gaps = 7/193 (3%) Query: 103 REAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEE 162 ++ Q+ Q + + E+ E K + + Q+ AR L ++EEE Sbjct: 593 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 652 Query: 163 KQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYG 222 +++H + + +++ + ER + EA AE+ E + E E+E E + R E Sbjct: 653 ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 712 Query: 223 LEAAPEKDTVVRCLRTRTRMDEEVSDPTSA-AAQLRQLPGPLASPSSASPSRALPEPQ-- 279 + A ++ R + R + + E+ + A Q QL L + L E Q Sbjct: 713 RQLAEQER---RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769 Query: 280 -EAQKLAAERARA 291 E +K A E A A Sbjct: 770 EEQEKKAKEAAGA 782 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 37.4 bits (85), Expect = 0.029 Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 17/143 (11%) Query: 104 EAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEK 163 E +RLR+ R E EK E +K+ R KK+ Q+ R E+ +EEE+ Sbjct: 401 EQDERLREKEERMRE--QEKMWEQVEKM-------REEKKMQEQEKKTRDQEEKMQEEER 451 Query: 164 QKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLRPEYGL 223 + +K RE ++T + + + +E+ E EKE + +P+ + Sbjct: 452 IREREK--------KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503 Query: 224 EAAPEKDTVVRCLRTRTRMDEEV 246 E E++ + + R EE+ Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEM 526 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 37.4 bits (85), Expect = 0.029 Identities = 39/150 (26%), Positives = 57/150 (38%), Gaps = 25/150 (16%) Query: 145 DFQDTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVP 204 D N S E + EEE+++ ++ +E E E + E + EE+E++E E Sbjct: 877 DLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFE 936 Query: 205 EKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPG--- 261 E+EG L E E E++ + EEV D A G Sbjct: 937 EEEG-------ELEEEEEEEDEEEEEEL-----------EEVEDLEFGTAGGEVEEGAPP 978 Query: 262 ----PLASPSSASPSRALPEPQEAQKLAAE 287 P A P SP + PEP+ L E Sbjct: 979 PPTLPPALPPPESPPKVQPEPEPEPGLLLE 1008 Score = 30.0 bits (66), Expect = 4.7 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 6/58 (10%) Query: 160 EEEKQKHLDKIYQERASQAEREMQ-QTEALGDAEEDEDD-----EDFVEVPEKEGYEP 211 EEE + DK+ + AE EM+ +TEA E+++DD DF++ P + P Sbjct: 1066 EEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPP 1123 >gi|168229156 NFKB activating protein [Homo sapiens] Length = 415 Score = 37.0 bits (84), Expect = 0.038 Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 148 DTNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKE 207 + N R + K++E+K+KH K Y+++ S+ R+ D+ E E+F+E P K+ Sbjct: 226 EDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES-----SDSSSKESQEEFLENPWKD 280 Query: 208 GYEPHIPDHL 217 + P L Sbjct: 281 RTKAEEPSDL 290 >gi|169168458 PREDICTED: hypothetical protein [Homo sapiens] Length = 353 Score = 37.0 bits (84), Expect = 0.038 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 7/90 (7%) Query: 206 KEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLAS 265 +EG H+P +RP + AP ++ R R + PTS R P PLAS Sbjct: 121 REGSSHHLPRQVRPGPVYKPAPARNH-------RPRGGRGKASPTSFHVSPRAPPAPLAS 173 Query: 266 PSSASPSRALPEPQEAQKLAAERARAPVVP 295 S+ P ++ L++ +A P+ P Sbjct: 174 MPSSVPKTSIESLGSPSSLSSSQASEPLCP 203 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 37.0 bits (84), Expect = 0.038 Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 5/105 (4%) Query: 147 QDTNARSLAERKREEEKQKHLDKIYQERASQAERE---MQQTEALGDAEE--DEDDEDFV 201 QD R ER RE+EK ++ QE ERE ++ E + + EE + +E+ Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423 Query: 202 EVPEKEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEV 246 E EKE + +P+ + E E++ + + R EE+ Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468 Score = 34.7 bits (78), Expect = 0.19 Identities = 68/368 (18%), Positives = 145/368 (39%), Gaps = 40/368 (10%) Query: 103 REAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAER--KRE 160 RE ++R+ + + ++ E K+L LR KK+ Q+ + E+ ++E Sbjct: 265 REQEGKMREQEEK-MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323 Query: 161 EEKQKHLDKIY--QERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHIPDHLR 218 E+ ++ +K++ +ER + E++M++ E +E+ E + EKE + +R Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-------ERMR 376 Query: 219 PEYGLEAAPEKDTVVRCLRTRTRM--DEEVSDPTSAAAQLRQLPGPLASPSSASPSRALP 276 + + EK +R R + +EE + +Q + LP Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436 Query: 277 EPQEA----QKLAAERARAPVVPYGVDLHYWGQELPTAGKIVKSDSQHRFWKPSEV-EEE 331 E +E +K+ + + W QE + + + W+ ++ E+E Sbjct: 437 EQKEKLWEQEKMQEQEEKI-----------WEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485 Query: 332 VVNADISEMLRSRHITFAGKFEPVQHWCRAPRPDGRLCERQDRLKE----WQDPELMRDV 387 + E +R + + E R D RL E+++R++E WQ E MR+ Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEE------RMWEQDERLREKEERMREQKKMWQQEEKMREE 539 Query: 388 EAATGQDLGSSRYSGKGRGKKRRYPSLTNLKAQADTARARIGRKVFAKAAVRRVVAAMNR 447 + Q+ + K R ++R ++ + + R + + + +R M Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599 Query: 448 MDQKKHEK 455 ++K E+ Sbjct: 600 QEEKMQEQ 607 >gi|239742749 PREDICTED: hypothetical protein XP_002342626 [Homo sapiens] Length = 277 Score = 37.0 bits (84), Expect = 0.038 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 7/90 (7%) Query: 206 KEGYEPHIPDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLAS 265 +EG H+P +RP + AP ++ R R + PTS R P PLAS Sbjct: 121 REGSSHHLPRQVRPGPVYKPAPARNH-------RPRGGRGKASPTSFHVSPRAPPAPLAS 173 Query: 266 PSSASPSRALPEPQEAQKLAAERARAPVVP 295 S+ P ++ L++ +A P+ P Sbjct: 174 MPSSVPKTSIESLGSPSSLSSSQASEPLCP 203 >gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] Length = 1312 Score = 37.0 bits (84), Expect = 0.038 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 6/83 (7%) Query: 141 NKKVDFQDTNARSLAER-----KREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDE 195 N+ +D +D + + E + EEEK K D+ +E + + E ++ E + EEDE Sbjct: 497 NENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEE-DEDDEEAEEEEEEEEEEEDE 555 Query: 196 DDEDFVEVPEKEGYEPHIPDHLR 218 DD+D E E E Y P + +R Sbjct: 556 DDDDNNEEEEFECYPPGMKVQVR 578 Score = 30.4 bits (67), Expect = 3.6 Identities = 48/252 (19%), Positives = 97/252 (38%), Gaps = 17/252 (6%) Query: 6 SKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIV 65 ++L E+ ++S E+ E +K SSEE+ I +E ++ + Sbjct: 267 TELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEE------IEPFPEERENFLQQLYKFM 320 Query: 66 EELFVRSHQFRMLVVSNFQEFLELTL-----GTDPAQPLPPPREAAQRLRQATTRAVEGW 120 E+ ++ +L N F L G D + ++ Q L + G+ Sbjct: 321 EDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGY 380 Query: 121 NEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERASQAER 180 N K AYKK G+ + ++FQ + ++ +E + K+ +E ++ + Sbjct: 381 NVKC--AYKKYLYGFEEYCRSANIEFQMALPEKVVNKQCKECENVKEIKVKEENETEIKE 438 Query: 181 EMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI--PDHLRPEYGLEAAPEKDTVVRCLRT 238 + E E++ ED E+ KE +P + +L + EK+ ++ Sbjct: 439 IKMEEERNIIPREEKPIED--EIERKENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPED 496 Query: 239 RTRMDEEVSDPT 250 +D++ D T Sbjct: 497 NENLDDKDDDTT 508 >gi|231570186 zinc finger CCCH-type containing 14 isoform 6 [Homo sapiens] Length = 730 Score = 36.6 bits (83), Expect = 0.050 Identities = 40/211 (18%), Positives = 80/211 (37%), Gaps = 32/211 (15%) Query: 158 KREEEKQKHLDKIYQERASQAEREMQQTEALG-DAEEDEDDEDF----------VEVPEK 206 + EK D+ +++R + + + D EE+E+D+D+ V VP K Sbjct: 278 RNNSEKMSMEDENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDYGSRTGSISSSVSVPAK 337 Query: 207 EGYEPHIPDHLRPEYGL------------------EAAPEKDTVVRCLRTRTRMDEEVSD 248 P +P + L P+K T+ RTRT +E +++ Sbjct: 338 PERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVPQKQTLPVAPRTRTSQEELLAE 397 Query: 249 PTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELP 308 ++ ++ P+ + S + + ++L +R + P + Q+ Sbjct: 398 VVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQRQLL---SRLQIDPVMAETLQMSQDYY 454 Query: 309 TAGKIVKSDSQHRFWKPSEVEEEVVNADISE 339 +V +D++ K ++ EEVV A E Sbjct: 455 DMESMVHADTRSFILKKPKLSEEVVVAPNQE 485 >gi|231570121 zinc finger CCCH-type containing 14 isoform 5 [Homo sapiens] Length = 735 Score = 36.6 bits (83), Expect = 0.050 Identities = 40/211 (18%), Positives = 80/211 (37%), Gaps = 32/211 (15%) Query: 158 KREEEKQKHLDKIYQERASQAEREMQQTEALG-DAEEDEDDEDF----------VEVPEK 206 + EK D+ +++R + + + D EE+E+D+D+ V VP K Sbjct: 278 RNNSEKMSMEDENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDYGSRTGSISSSVSVPAK 337 Query: 207 EGYEPHIPDHLRPEYGL------------------EAAPEKDTVVRCLRTRTRMDEEVSD 248 P +P + L P+K T+ RTRT +E +++ Sbjct: 338 PERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVPQKQTLPVAPRTRTSQEELLAE 397 Query: 249 PTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELP 308 ++ ++ P+ + S + + ++L +R + P + Q+ Sbjct: 398 VVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQRQLL---SRLQIDPVMAETLQMSQDYY 454 Query: 309 TAGKIVKSDSQHRFWKPSEVEEEVVNADISE 339 +V +D++ K ++ EEVV A E Sbjct: 455 DMESMVHADTRSFILKKPKLSEEVVVAPNQE 485 >gi|40804742 zinc finger CCCH-type containing 14 isoform 1 [Homo sapiens] Length = 736 Score = 36.6 bits (83), Expect = 0.050 Identities = 40/211 (18%), Positives = 80/211 (37%), Gaps = 32/211 (15%) Query: 158 KREEEKQKHLDKIYQERASQAEREMQQTEALG-DAEEDEDDEDF----------VEVPEK 206 + EK D+ +++R + + + D EE+E+D+D+ V VP K Sbjct: 278 RNNSEKMSMEDENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDYGSRTGSISSSVSVPAK 337 Query: 207 EGYEPHIPDHLRPEYGL------------------EAAPEKDTVVRCLRTRTRMDEEVSD 248 P +P + L P+K T+ RTRT +E +++ Sbjct: 338 PERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVPQKQTLPVAPRTRTSQEELLAE 397 Query: 249 PTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARAPVVPYGVDLHYWGQELP 308 ++ ++ P+ + S + + ++L +R + P + Q+ Sbjct: 398 VVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQRQLL---SRLQIDPVMAETLQMSQDYY 454 Query: 309 TAGKIVKSDSQHRFWKPSEVEEEVVNADISE 339 +V +D++ K ++ EEVV A E Sbjct: 455 DMESMVHADTRSFILKKPKLSEEVVVAPNQE 485 >gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapiens] Length = 875 Score = 36.6 bits (83), Expect = 0.050 Identities = 48/216 (22%), Positives = 89/216 (41%), Gaps = 21/216 (9%) Query: 5 LSKLVEELTTSGEPRLNPEKM----KELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLS 60 + +L+++ E ++NPEK+ K+L+ I ++ RA R ++ + + Sbjct: 427 VQQLLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVYLMKDKE 486 Query: 61 AFQIVEELFVRSHQFRM-LVVSNFQEFLELTLGTDPAQPL---PPPREAAQRLRQATTRA 116 F V +L + + + L V+ FL+ + P + L + R T Sbjct: 487 VFD-VSKLPIPEYALSLGLAVAPRVRFLQ-KMQKQPTKELVRSQADKVIEPRAPSLTNDE 544 Query: 117 VEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAERKREEEKQKHLDKIYQERAS 176 VE + F E L G L + DT E + +EE+ + +K+ + + S Sbjct: 545 VEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEEME--EKLAKAKGS 602 Query: 177 QAEREMQQTEALG---------DAEEDEDDEDFVEV 203 QA +EA D +E+E+D DF++V Sbjct: 603 QAPSLPNTSEAQKIKEVPTQFLDRDEEEEDADFLKV 638 Score = 31.6 bits (70), Expect = 1.6 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 14/67 (20%) Query: 156 ERKREEEKQKHLDKIYQERASQAEREMQQT------EALGDAEEDEDDEDFVEVPEKEGY 209 E R++ K KH +K +ER ++ E +Q EA D +D+DD+D +G+ Sbjct: 738 EEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWSDDDDDDD-------DGF 790 Query: 210 EPH-IPD 215 +P +PD Sbjct: 791 DPSTLPD 797 >gi|41322923 plectin 1 isoform 11 [Homo sapiens] Length = 4547 Score = 36.6 bits (83), Expect = 0.050 Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%) Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83 K++E +++ + +E++ +R QL QE A+ RL A + ++H F V Sbjct: 2017 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2061 Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143 ++ L+ TL + + L R A+ R+A A E + EA + R + Sbjct: 2062 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120 Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200 + Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2173 Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249 E + +K E + DH + E K R R++++EE+ Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233 Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302 +L +L + + + A + R L E E K AE A L Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2285 Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361 QE ++ + D +Q R ++E++ + L++ + E Q R Sbjct: 2286 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2345 Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416 + D +L E + + E R +E + + R + R + R Sbjct: 2346 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405 Query: 417 LKAQADTARARIGRKVFA 434 + QA+ ++ R A Sbjct: 2406 FRKQAEEIGEKLHRTELA 2423 Score = 33.5 bits (75), Expect = 0.42 Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%) Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61 ++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S Sbjct: 1396 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1447 Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121 +I EE+ V Q EL A+ + AQ + R V+ + Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1507 Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177 ++ +A +LA R + + R+L R + EE ++ L + ERA Q Sbjct: 1508 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1562 Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234 + ++ + +AE F E E+ E H+ E A ++ R Sbjct: 1563 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1622 Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291 R E + A +LR +A S + + A + +EA++ A R +A Sbjct: 1623 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1679 Score = 33.1 bits (74), Expect = 0.55 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%) Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213 LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++ Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1421 Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272 LR E + R+R R++EE+ A RQ G + Sbjct: 1422 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1478 Query: 273 RALPEPQEAQKLAAE 287 RA E EAQK A+ Sbjct: 1479 RARAEEAEAQKRQAQ 1493 Score = 32.7 bits (73), Expect = 0.72 Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%) Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62 Q+ + +EEL E + E+++ + + L A R A+L + A Sbjct: 1532 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1590 Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122 Q+ RS Q + V+ +E A+ + A+R R+ R +E W Sbjct: 1591 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1636 Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174 K EA + LR ++V Q + A++ AE+++EE +++ + Q Sbjct: 1637 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1688 Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228 ++ E E Q+ A G A+ E E E + E + + L R + AA + Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1748 Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288 K + + R + EV + A A+ S S S R E ++LA E Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1803 Query: 289 AR 290 AR Sbjct: 1804 AR 1805 Score = 30.8 bits (68), Expect = 2.7 Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%) Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60 +L +L EE + R EKM + K +L LL Q L QE A ++ Sbjct: 2292 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2349 Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112 Q+ ++L + F+ + + Q LE++ + ++ E AQR R+ Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409 Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171 E + +K+ L ++ D R ++AE +RE+EK + K+ Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469 Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202 Q ++ Q E+ +Q+T+AL + E D E F+E Sbjct: 2470 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2510 >gi|41322914 plectin 1 isoform 10 [Homo sapiens] Length = 4551 Score = 36.6 bits (83), Expect = 0.050 Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%) Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83 K++E +++ + +E++ +R QL QE A+ RL A + ++H F V Sbjct: 2021 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2065 Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143 ++ L+ TL + + L R A+ R+A A E + EA + R + Sbjct: 2066 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2124 Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200 + Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F Sbjct: 2125 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2177 Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249 E + +K E + DH + E K R R++++EE+ Sbjct: 2178 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2237 Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302 +L +L + + + A + R L E E K AE A L Sbjct: 2238 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2289 Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361 QE ++ + D +Q R ++E++ + L++ + E Q R Sbjct: 2290 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2349 Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416 + D +L E + + E R +E + + R + R + R Sbjct: 2350 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2409 Query: 417 LKAQADTARARIGRKVFA 434 + QA+ ++ R A Sbjct: 2410 FRKQAEEIGEKLHRTELA 2427 Score = 33.5 bits (75), Expect = 0.42 Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%) Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61 ++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S Sbjct: 1400 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1451 Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121 +I EE+ V Q EL A+ + AQ + R V+ + Sbjct: 1452 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1511 Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177 ++ +A +LA R + + R+L R + EE ++ L + ERA Q Sbjct: 1512 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1566 Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234 + ++ + +AE F E E+ E H+ E A ++ R Sbjct: 1567 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1626 Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291 R E + A +LR +A S + + A + +EA++ A R +A Sbjct: 1627 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1683 Score = 33.1 bits (74), Expect = 0.55 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%) Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213 LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++ Sbjct: 1366 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1425 Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272 LR E + R+R R++EE+ A RQ G + Sbjct: 1426 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1482 Query: 273 RALPEPQEAQKLAAE 287 RA E EAQK A+ Sbjct: 1483 RARAEEAEAQKRQAQ 1497 Score = 32.7 bits (73), Expect = 0.72 Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%) Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62 Q+ + +EEL E + E+++ + + L A R A+L + A Sbjct: 1536 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1594 Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122 Q+ RS Q + V+ +E A+ + A+R R+ R +E W Sbjct: 1595 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1640 Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174 K EA + LR ++V Q + A++ AE+++EE +++ + Q Sbjct: 1641 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1692 Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228 ++ E E Q+ A G A+ E E E + E + + L R + AA + Sbjct: 1693 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1752 Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288 K + + R + EV + A A+ S S S R E ++LA E Sbjct: 1753 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1807 Query: 289 AR 290 AR Sbjct: 1808 AR 1809 Score = 30.8 bits (68), Expect = 2.7 Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%) Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60 +L +L EE + R EKM + K +L LL Q L QE A ++ Sbjct: 2296 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2353 Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112 Q+ ++L + F+ + + Q LE++ + ++ E AQR R+ Sbjct: 2354 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2413 Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171 E + +K+ L ++ D R ++AE +RE+EK + K+ Sbjct: 2414 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2473 Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202 Q ++ Q E+ +Q+T+AL + E D E F+E Sbjct: 2474 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2514 >gi|41322919 plectin 1 isoform 8 [Homo sapiens] Length = 4547 Score = 36.6 bits (83), Expect = 0.050 Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%) Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83 K++E +++ + +E++ +R QL QE A+ RL A + ++H F V Sbjct: 2017 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2061 Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143 ++ L+ TL + + L R A+ R+A A E + EA + R + Sbjct: 2062 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120 Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200 + Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2173 Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249 E + +K E + DH + E K R R++++EE+ Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233 Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302 +L +L + + + A + R L E E K AE A L Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2285 Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361 QE ++ + D +Q R ++E++ + L++ + E Q R Sbjct: 2286 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2345 Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416 + D +L E + + E R +E + + R + R + R Sbjct: 2346 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405 Query: 417 LKAQADTARARIGRKVFA 434 + QA+ ++ R A Sbjct: 2406 FRKQAEEIGEKLHRTELA 2423 Score = 33.5 bits (75), Expect = 0.42 Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%) Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61 ++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S Sbjct: 1396 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1447 Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121 +I EE+ V Q EL A+ + AQ + R V+ + Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1507 Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177 ++ +A +LA R + + R+L R + EE ++ L + ERA Q Sbjct: 1508 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1562 Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234 + ++ + +AE F E E+ E H+ E A ++ R Sbjct: 1563 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1622 Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291 R E + A +LR +A S + + A + +EA++ A R +A Sbjct: 1623 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1679 Score = 33.1 bits (74), Expect = 0.55 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%) Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213 LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++ Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1421 Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272 LR E + R+R R++EE+ A RQ G + Sbjct: 1422 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1478 Query: 273 RALPEPQEAQKLAAE 287 RA E EAQK A+ Sbjct: 1479 RARAEEAEAQKRQAQ 1493 Score = 32.7 bits (73), Expect = 0.72 Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%) Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62 Q+ + +EEL E + E+++ + + L A R A+L + A Sbjct: 1532 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1590 Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122 Q+ RS Q + V+ +E A+ + A+R R+ R +E W Sbjct: 1591 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1636 Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174 K EA + LR ++V Q + A++ AE+++EE +++ + Q Sbjct: 1637 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1688 Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228 ++ E E Q+ A G A+ E E E + E + + L R + AA + Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1748 Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288 K + + R + EV + A A+ S S S R E ++LA E Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1803 Query: 289 AR 290 AR Sbjct: 1804 AR 1805 Score = 30.8 bits (68), Expect = 2.7 Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%) Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60 +L +L EE + R EKM + K +L LL Q L QE A ++ Sbjct: 2292 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2349 Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112 Q+ ++L + F+ + + Q LE++ + ++ E AQR R+ Sbjct: 2350 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2409 Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171 E + +K+ L ++ D R ++AE +RE+EK + K+ Sbjct: 2410 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2469 Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202 Q ++ Q E+ +Q+T+AL + E D E F+E Sbjct: 2470 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2510 >gi|41322910 plectin 1 isoform 7 [Homo sapiens] Length = 4515 Score = 36.6 bits (83), Expect = 0.050 Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%) Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83 K++E +++ + +E++ +R QL QE A+ RL A + ++H F V Sbjct: 1985 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2029 Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143 ++ L+ TL + + L R A+ R+A A E + EA + R + Sbjct: 2030 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2088 Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200 + Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F Sbjct: 2089 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2141 Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249 E + +K E + DH + E K R R++++EE+ Sbjct: 2142 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2201 Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302 +L +L + + + A + R L E E K AE A L Sbjct: 2202 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2253 Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361 QE ++ + D +Q R ++E++ + L++ + E Q R Sbjct: 2254 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2313 Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416 + D +L E + + E R +E + + R + R + R Sbjct: 2314 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2373 Query: 417 LKAQADTARARIGRKVFA 434 + QA+ ++ R A Sbjct: 2374 FRKQAEEIGEKLHRTELA 2391 Score = 33.5 bits (75), Expect = 0.42 Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%) Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61 ++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S Sbjct: 1364 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1415 Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121 +I EE+ V Q EL A+ + AQ + R V+ + Sbjct: 1416 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1475 Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177 ++ +A +LA R + + R+L R + EE ++ L + ERA Q Sbjct: 1476 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1530 Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234 + ++ + +AE F E E+ E H+ E A ++ R Sbjct: 1531 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1590 Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291 R E + A +LR +A S + + A + +EA++ A R +A Sbjct: 1591 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1647 Score = 33.1 bits (74), Expect = 0.55 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%) Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213 LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++ Sbjct: 1330 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1389 Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272 LR E + R+R R++EE+ A RQ G + Sbjct: 1390 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1446 Query: 273 RALPEPQEAQKLAAE 287 RA E EAQK A+ Sbjct: 1447 RARAEEAEAQKRQAQ 1461 Score = 32.7 bits (73), Expect = 0.72 Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%) Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62 Q+ + +EEL E + E+++ + + L A R A+L + A Sbjct: 1500 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1558 Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122 Q+ RS Q + V+ +E A+ + A+R R+ R +E W Sbjct: 1559 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1604 Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174 K EA + LR ++V Q + A++ AE+++EE +++ + Q Sbjct: 1605 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1656 Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228 ++ E E Q+ A G A+ E E E + E + + L R + AA + Sbjct: 1657 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1716 Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288 K + + R + EV + A A+ S S S R E ++LA E Sbjct: 1717 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1771 Query: 289 AR 290 AR Sbjct: 1772 AR 1773 Score = 30.8 bits (68), Expect = 2.7 Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%) Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60 +L +L EE + R EKM + K +L LL Q L QE A ++ Sbjct: 2260 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2317 Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112 Q+ ++L + F+ + + Q LE++ + ++ E AQR R+ Sbjct: 2318 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2377 Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171 E + +K+ L ++ D R ++AE +RE+EK + K+ Sbjct: 2378 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2437 Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202 Q ++ Q E+ +Q+T+AL + E D E F+E Sbjct: 2438 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2478 >gi|41322916 plectin 1 isoform 6 [Homo sapiens] Length = 4684 Score = 36.6 bits (83), Expect = 0.050 Identities = 90/438 (20%), Positives = 166/438 (37%), Gaps = 58/438 (13%) Query: 24 KMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAFQIVEELFVRSHQFRMLVVSNF 83 K++E +++ + +E++ +R QL QE A+ RL A + ++H F V Sbjct: 2154 KVEEARRLRERAEQESARQL-----QLAQEAAQKRLQAEE-------KAHAF---AVQQK 2198 Query: 84 QEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNEKFGEAYKKLALGYHFLRHNKK 143 ++ L+ TL + + L R A+ R+A A E + EA + R + Sbjct: 2199 EQELQQTLQQEQSV-LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2257 Query: 144 VDFQD---TNARSLAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDF 200 + Q A++ AE+ R+E +Q+ R +QAE+ + + DAE E + F Sbjct: 2258 AEEQAQARAQAQAAAEKLRKEAEQE------AARRAQAEQAALRQKQAADAEM-EKHKKF 2310 Query: 201 VE--VPEKEGYEPHI---------PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVSDP 249 E + +K E + DH + E K R R++++EE+ Sbjct: 2311 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2370 Query: 250 TSAAAQLRQLPGPLASPSSA-------SPSRALPEPQEAQKLAAERARAPVVPYGVDLHY 302 +L +L + + + A + R L E E K AE A L Sbjct: 2371 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA--------ARLSV 2422 Query: 303 WGQELPTAGKIVKSD-SQHRFWKPSEVEEEVVNADISEMLRSRHITFAGKFEPVQHWCRA 361 QE ++ + D +Q R ++E++ + L++ + E Q R Sbjct: 2423 AAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARR 2482 Query: 362 PRPD-----GRLCERQDRLKEWQDPELMRDVEAATGQDLGSSRYSGKGRGKKRRYPSLTN 416 + D +L E + + E R +E + + R + R + R Sbjct: 2483 LQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2542 Query: 417 LKAQADTARARIGRKVFA 434 + QA+ ++ R A Sbjct: 2543 FRKQAEEIGEKLHRTELA 2560 Score = 33.5 bits (75), Expect = 0.42 Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 25/297 (8%) Query: 7 KLVEELTTSGEPRLNPEKMK-----ELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSA 61 ++ EE+ E ++ ++ K EL+++ +SSE ++ A+ Q A R S Sbjct: 1533 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ-------AKARQAEAAER-SR 1584 Query: 62 FQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWN 121 +I EE+ V Q EL A+ + AQ + R V+ + Sbjct: 1585 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDES 1644 Query: 122 EKFGEAYKKLALGYHFLRHNKKVDFQDTNARSLAE----RKREEEKQKHLDKIYQERASQ 177 ++ +A +LA R + + R+L R + EE ++ L + ERA Q Sbjct: 1645 QRKRQAEVELAS-----RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ 1699 Query: 178 AEREMQQTEALGDAEEDEDDEDFVEVP---EKEGYEPHIPDHLRPEYGLEAAPEKDTVVR 234 + ++ + +AE F E E+ E H+ E A ++ R Sbjct: 1700 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER 1759 Query: 235 CLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAERARA 291 R E + A +LR +A S + + A + +EA++ A R +A Sbjct: 1760 AREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1816 Score = 33.1 bits (74), Expect = 0.55 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 4/135 (2%) Query: 154 LAERKREEEKQKHLDKIYQERASQAEREMQQTEALGDAEEDEDDEDFVEVPEKEGYEPHI 213 LAE + EKQ+ L + + + +QAERE ++ + E +E V+ +++ Sbjct: 1499 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1558 Query: 214 PDHLRPEYGLEAAPEKDTVVRCLRTRTRMDEEVS-DPTSAAAQLRQLPGPLASPSSASPS 272 LR E + R+R R++EE+ A RQ G + Sbjct: 1559 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG---AEGELQAL 1615 Query: 273 RALPEPQEAQKLAAE 287 RA E EAQK A+ Sbjct: 1616 RARAEEAEAQKRQAQ 1630 Score = 32.7 bits (73), Expect = 0.72 Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 42/302 (13%) Query: 3 QKLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQLTQEHAEIRLSAF 62 Q+ + +EEL E + E+++ + + L A R A+L + A Sbjct: 1669 QRALQALEELRLQAEEAERRLRQAEVER-ARQVQVALETAQRSAEAELQSKRASFAEKTA 1727 Query: 63 QIVEELFVRSHQFRMLVVSNFQEFLELTLGTDPAQPLPPPREAAQRLRQATTRAVEGWNE 122 Q+ RS Q + V+ +E A+ + A+R R+ R +E W Sbjct: 1728 QLE-----RSLQEEHVAVAQLRE---------EAERRAQQQAEAERAREEAERELERWQL 1773 Query: 123 KFGEAYKKLALGYHFLR-HNKKVDFQDTNARSLAERKREEEKQK-------HLDKIYQER 174 K EA + LR ++V Q + A++ AE+++EE +++ + Q Sbjct: 1774 KANEALR--------LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRE 1825 Query: 175 ASQAEREMQQTEALGDAE-----EDEDDEDFVEVPEKEGYEPHIPDHL-RPEYGLEAAPE 228 ++ E E Q+ A G A+ E E E + E + + L R + AA + Sbjct: 1826 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1885 Query: 229 KDTVVRCLRTRTRMDEEVSDPTSAAAQLRQLPGPLASPSSASPSRALPEPQEAQKLAAER 288 K + + R + EV + A A+ S S S R E ++LA E Sbjct: 1886 KRQELEAELAKVRAEMEVLLASKARAEEES-----RSTSEKSKQRLEAEAGRFRELAEEA 1940 Query: 289 AR 290 AR Sbjct: 1941 AR 1942 Score = 30.8 bits (68), Expect = 2.7 Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 24/221 (10%) Query: 4 KLSKLVEELTTSGEPRLNPEKMKELKKICKSSEEQLSRAYRLLIAQ--LTQEHAE-IRLS 60 +L +L EE + R EKM + K +L LL Q L QE A ++ Sbjct: 2429 RLRQLAEE--DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED 2486 Query: 61 AFQIVEELFVRSHQFRMLVVSNFQEFLELTLGTDP--------AQPLPPPREAAQRLRQA 112 Q+ ++L + F+ + + Q LE++ + ++ E AQR R+ Sbjct: 2487 KEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ 2546 Query: 113 TTRAVEGWNEKFGEAYKKLALGYHFLRHNKKVDFQDTNAR-SLAERKREEEKQKHLDKIY 171 E + +K+ L ++ D R ++AE +RE+EK + K+ Sbjct: 2547 AEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLL 2606 Query: 172 QERAS-----QAEREMQQTEALGDAEEDEDD-----EDFVE 202 Q ++ Q E+ +Q+T+AL + E D E F+E Sbjct: 2607 QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2647 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.130 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,607,689 Number of Sequences: 37866 Number of extensions: 937897 Number of successful extensions: 8160 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 95 Number of HSP's successfully gapped in prelim test: 332 Number of HSP's that attempted gapping in prelim test: 6687 Number of HSP's gapped (non-prelim): 1399 length of query: 465 length of database: 18,247,518 effective HSP length: 106 effective length of query: 359 effective length of database: 14,233,722 effective search space: 5109906198 effective search space used: 5109906198 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.