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Search of human proteins with 239747793
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
(868 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 1697 0.0
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 1659 0.0
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 1608 0.0
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 1505 0.0
gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 828 0.0
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 570 e-162
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 546 e-155
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 546 e-155
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 544 e-154
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 378 e-104
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 349 6e-96
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 315 1e-85
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 280 4e-75
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 259 1e-68
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 255 1e-67
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 251 2e-66
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 251 2e-66
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 223 5e-58
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 223 5e-58
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 223 5e-58
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 221 3e-57
gi|169217530 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 216 6e-56
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 211 2e-54
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 211 2e-54
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 211 2e-54
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 201 3e-51
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 201 3e-51
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 201 3e-51
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 125 1e-28
gi|239754871 PREDICTED: similar to Coiled-coil domain-containing... 124 3e-28
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 1697 bits (4396), Expect = 0.0
Identities = 868/868 (100%), Positives = 868/868 (100%)
Query: 1 MNPFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSV 60
MNPFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSV
Sbjct: 1 MNPFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSV 60
Query: 61 PNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKA 120
PNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKA
Sbjct: 61 PNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKA 120
Query: 121 TSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSP 180
TSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSP
Sbjct: 121 TSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSP 180
Query: 181 QKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDV 240
QKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDV
Sbjct: 181 QKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDV 240
Query: 241 QTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCC 300
QTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCC
Sbjct: 241 QTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCC 300
Query: 301 NCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVL 360
NCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVL
Sbjct: 301 NCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVL 360
Query: 361 QKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQY 420
QKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQY
Sbjct: 361 QKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQY 420
Query: 421 RIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDT 480
RIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDT
Sbjct: 421 RIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDT 480
Query: 481 IKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKL 540
IKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKL
Sbjct: 481 IKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKL 540
Query: 541 EKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHV 600
EKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHV
Sbjct: 541 EKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHV 600
Query: 601 LILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGY 660
LILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGY
Sbjct: 601 LILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGY 660
Query: 661 NTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECR 720
NTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECR
Sbjct: 661 NTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECR 720
Query: 721 KHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLD 780
KHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLD
Sbjct: 721 KHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLD 780
Query: 781 ASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRK 840
ASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRK
Sbjct: 781 ASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRK 840
Query: 841 IIKKQDEQIERFEKILQHSSLMLQVFES 868
IIKKQDEQIERFEKILQHSSLMLQVFES
Sbjct: 841 IIKKQDEQIERFEKILQHSSLMLQVFES 868
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 1659 bits (4296), Expect = 0.0
Identities = 850/862 (98%), Positives = 856/862 (99%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSSE+P GLKAT DEKDS+LNIARGKK+GEKTRRVSSHKQPALKATSDKENSVPNMATE
Sbjct: 569 TVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATE 628
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ AWKATSVKKD
Sbjct: 629 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKD 688
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ
Sbjct: 689 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 748
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA
Sbjct: 749 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 808
Query: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 306
EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI
Sbjct: 809 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 868
Query: 307 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE 366
LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE
Sbjct: 869 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE 928
Query: 367 KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 426
KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV
Sbjct: 929 KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 988
Query: 427 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 486
TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL
Sbjct: 989 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 1048
Query: 487 EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES 546
EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES
Sbjct: 1049 EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES 1108
Query: 547 GQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQ 606
GQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQ
Sbjct: 1109 GQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQ 1168
Query: 607 LSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 666
LSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC
Sbjct: 1169 LSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 1228
Query: 667 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 726
IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL
Sbjct: 1229 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 1288
Query: 727 EEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC 786
EEDNKMLVNEL HSKEK+CQYEKEKAEREVAVRQLQQK+DDVLNK SATKALLDASSRHC
Sbjct: 1289 EEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDASSRHC 1348
Query: 787 TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQD 846
YLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQD
Sbjct: 1349 IYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQD 1408
Query: 847 EQIERFEKILQHSSLMLQVFES 868
EQIERFEKILQHSSLMLQVFES
Sbjct: 1409 EQIERFEKILQHSSLMLQVFES 1430
Score = 266 bits (680), Expect = 6e-71
Identities = 279/951 (29%), Positives = 422/951 (44%), Gaps = 141/951 (14%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+K LKAT+DE+DSV NIA K GEK+ VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 399 TVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATE 458
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD + S TVSSQKQPALKAT+D++DSVS I TEIKDG++SGTVSS+K+PA KATS +KD
Sbjct: 459 IKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKD 518
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
S SNI E KDG+I TVSSQ+ PALKAT DE+DSV +IARE KDGEKS TVS ++
Sbjct: 519 SFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGL 578
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
K +K SLLNIA G K+ P LKAT + +NSV N AT+ KD Q S
Sbjct: 579 KATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTV 638
Query: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHS-----------------RDDLDDII---- 285
+ A + + + N ++K+ S +D + +I
Sbjct: 639 SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIK 698
Query: 286 ----------QSSQTVSEDGDSLCCNCKNVILLIDQHEMK-----CKDCVHLLKIKKTFC 330
Q + GD + N+ I E K + KK
Sbjct: 699 DGQIRGTVSSQRQPALKATGDEK-DSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVS 757
Query: 331 LCKRLTELK------DNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKE 384
L T + + E L ++NK SVL K+ S + LE+
Sbjct: 758 LLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEM--- 814
Query: 385 LCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTG 444
A + E+K+ E +V+ ++ ++ + ++S++ + G
Sbjct: 815 ------ASEGEQKRLEEYENNQPQVKNQIHSRDD-----------LDDIIQSSQTVSEDG 857
Query: 445 G----NNSNQVSETDEKE----DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEI 496
N N + D+ E D +H ++ + RL + +K+ + E+ +K
Sbjct: 858 DSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTE--LKDNHCEQLRVK-IRK 914
Query: 497 VKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQS 556
+K K LQK L EE ++ + L E +LR ++++++ + +E Q
Sbjct: 915 LKNKASVLQKRLSEKEEIKSQ----LKHETLELEKELCSLRFAIQQEKKKRRNVEELHQK 970
Query: 557 YR---------CRLNAALCDHDQSHSSKRDQELAFQG--------TVDKCCHLQENLNSH 599
R R+ A + + + EL G T +K L EN
Sbjct: 971 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQ 1030
Query: 600 VLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSG 659
I L+L K K + LE + E +K K E +Q LK+ + + + Y
Sbjct: 1031 DEIARLRLEKDTIKNQNLEKKYLKDFEIVKRK---HEDLQKALKRNEETLAETIACYSGQ 1087
Query: 660 Y-------NTMEKCIEKQERFCQLKKQNMLLQQ--------QLDDARNKADNQEKAILNI 704
T+ +EKQ Q + M + D + + +QE A
Sbjct: 1088 LAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 1147
Query: 705 QARCDARVENLQAECRKHRLLL-------EEDNKMLVNELTHSKE--KECQYEKEKAERE 755
+C ENL + H L+L E ++L EL ++ E KE E + E
Sbjct: 1148 VDKCCHLQENLNS----HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSE 1203
Query: 756 VAVRQLQQKRDDVLNKG--SATKALLDASSRHC------TYLENGMQDSRKKLDQMRSQF 807
+ +Q Q K + + K + + ++ R C L+ + D+R K D
Sbjct: 1204 LKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAI 1263
Query: 808 QEIQDQLTATIRCTKEMEGDAQK----LEVENVMMRKIIKKQDEQIERFEK 854
IQ + A + + ++ + +K LE +N M+ + E+ ++EK
Sbjct: 1264 LNIQARCDARV---ENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEK 1311
Score = 266 bits (679), Expect = 8e-71
Identities = 276/921 (29%), Positives = 419/921 (45%), Gaps = 138/921 (14%)
Query: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
VSS+K KATSD+KDSV NIA K G + VSS KQPA KATSD+++SV N+ATE
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
Query: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
K+ Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQP KATS K DS
Sbjct: 324 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDS 383
Query: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
NIATEIKDG GTVSSQ+QPALKAT DE+DSVSNIA EIKDGEKSGTVS QKQ A K
Sbjct: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
Query: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247
++ S+LNIAT I G KS T + P LKAT + ++SV AT++KD + S
Sbjct: 444 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 503
Query: 248 QDLEMASEGEQKRLEEYENNQPQVKNQIHSR--------------DDLDDII-------- 285
+ A + + + N + K+ SR D+ D ++
Sbjct: 504 SRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKD 563
Query: 286 -QSSQTVSED---GDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK---------KTFCLC 332
+ S+TVS + G + K+ +L I + + + + K K +
Sbjct: 564 GEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVP 623
Query: 333 KRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKE--------EIKSQLKHETLELEKE 384
TE KD EQ+ + K A K S+K+ EIK + T+ +K+
Sbjct: 624 NMATETKD---EQISGTVSSQKQPA---LKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ 677
Query: 385 LCSLRFAIQQEKKKRRNVEELHQKVRE-KLRITEEQYRIEA-DVTKPIKPALKSAEVELK 442
L A + K+ +V + ++++ ++R T R A T K ++ + E+K
Sbjct: 678 L-----AWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIK 732
Query: 443 TGGNNSNQVSETDEKEDLLHENRLMQDEIA---------------RLRLEKDTIKNQNL- 486
G + + + ++ + ++ IA L K TI+N+N
Sbjct: 733 DGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSV 792
Query: 487 --EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQR 544
+KD + +DL+ A + ++ L E Y + ++ + R L+
Sbjct: 793 LNTATKMKDVQTSTPAEQDLEMASEGEQKRLEE----YENNQPQVKNQIHS-RDDLDDII 847
Query: 545 ESGQRLETEMQSYRCRLNAALCDHDQSHSSKRD--QELAFQGTVDKCCHLQENLNSHVLI 602
+S Q + + S C + DQ +D L + T C L E ++H
Sbjct: 848 QSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQ 907
Query: 603 LSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNT 662
L +++ K ++K VL+ + L EK E ++S+LK
Sbjct: 908 LRVKIRKLKNKASVLQ-------KRLSEK----EEIKSQLK------------------- 937
Query: 663 MEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKA-----ILNIQARCDARVENLQA 717
+ +E ++ C L+ +QQ+ RN + +K I Q R +A V
Sbjct: 938 -HETLELEKELCSLR---FAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIK 993
Query: 718 ECRKHRLLLEEDNKMLVNELTHSKEKE-CQYEKEKAEREVAVRQLQQKRDDVLNKGSATK 776
K + + N+++ + EKE +E + E+A +L+ ++D + N+ K
Sbjct: 994 PALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIA--RLRLEKDTIKNQNLEKK 1051
Query: 777 ALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENV 836
L D + ++K + ++ + ++ L TI C G L EN
Sbjct: 1052 YLKD------------FEIVKRKHEDLQKALKRNEETLAETIAC---YSGQLAALTDENT 1096
Query: 837 MMRKIIKKQDEQIERFEKILQ 857
+R ++KQ E +R E +Q
Sbjct: 1097 TLRSKLEKQRESGQRLETEMQ 1117
Score = 205 bits (521), Expect = 2e-52
Identities = 230/863 (26%), Positives = 369/863 (42%), Gaps = 105/863 (12%)
Query: 36 GEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVS 95
G+K VS + P T + + + D S SS++ P T + D S
Sbjct: 191 GQKAN-VSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSS 249
Query: 96 NIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKAT 155
KD G VSSQKQPA KATS KDSVSNIATEIK+G I GTVSSQ+QPA KAT
Sbjct: 250 KAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKAT 309
Query: 156 GDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPE 215
DEKDSVSNIA EIK+G++SGTVSPQKQSA KVIFKKKVSLLNIATRITGG KSGT +
Sbjct: 310 SDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQ 369
Query: 216 NLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQI 275
P KAT + +S LN AT++KD L+ + QK QP +K
Sbjct: 370 KQPPSKATSDKTDSALNIATEIKD---------GLQCGTVSSQK--------QPALK--- 409
Query: 276 HSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRL 335
+ D +D + + T +DG+ + Q +K + +
Sbjct: 410 -ATTDEEDSVSNIATEIKDGEK-----SGTVSSQKQPALKA-------TTDEEDSVLNIA 456
Query: 336 TELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQE 395
TE+KD K + ++ K +++E+ S + E + EK +
Sbjct: 457 TEIKDGE------KSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKS-----GTVSSR 505
Query: 396 KKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETD 455
KK + + ++ I V+ PALK+ T + +S
Sbjct: 506 KKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKA------TSDEEDSVLSIAR 559
Query: 456 EKEDLLHENRLMQDE----IARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRN 511
E++D ++R + E + R EKD++ N KKY + V + KA
Sbjct: 560 EEKD-GEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDK 618
Query: 512 EETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQS 571
E ++ A ++ + + Q++ + ++ + + + D QS
Sbjct: 619 ENSVPN---------MATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQS 669
Query: 572 HSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEK 631
+ ++LA++ T K + N I Q+ S R + L TG+
Sbjct: 670 GTVSSQKQLAWKATSVKKDSVS---NIATEIKDGQIRGTVSSQR--QPALKATGDEKDSV 724
Query: 632 ALVFEHVQSELK------QKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQ 685
+ + ++ K QKQS K I K S N + + + + L+
Sbjct: 725 SNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKA 784
Query: 686 QLDDARNKADNQEKAILNIQARCDARVE-NLQAECRKHRLLLEEDNKMLVNELTHSKE-- 742
+++ +N N + ++Q A + + +E + RL E+N+ V HS++
Sbjct: 785 TIEN-KNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDL 843
Query: 743 ----KECQYEKEKAER--------EVAVRQLQQKRDDVLN--KGSAT----KALLDASSR 784
+ Q E + + + Q + K D ++ K T K L +
Sbjct: 844 DDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDN 903
Query: 785 HCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKK 844
HC L R K+ +++++ +Q +L+ +++ + +LE E +R I++
Sbjct: 904 HCEQL-------RVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQ 956
Query: 845 QDEQIERFEKILQHSSLMLQVFE 867
+ ++ E++ Q L++ E
Sbjct: 957 EKKKRRNVEELHQKVREKLRITE 979
Score = 196 bits (499), Expect = 6e-50
Identities = 229/909 (25%), Positives = 393/909 (43%), Gaps = 99/909 (10%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VS E+P T + D + G + SS + P T + + A
Sbjct: 195 NVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMR 254
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD G VSSQKQPA KATSD KDSVSNI TEIK+G SGTVSSQKQPA KATS +KD
Sbjct: 255 RKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKD 314
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SVSNIATEIK+GQ GTVS Q+Q A K +K S+ NIA I G KSGTVS QKQ
Sbjct: 315 SVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPS 374
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS--- 243
K K S LNIAT I G + GT + P LKAT + ++SV N AT++KD + S
Sbjct: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
Query: 244 ----------TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSE 293
T E+D + E K E+ E Q + + + D +D + T +
Sbjct: 435 SSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIK 494
Query: 294 DGD--SLCCNCKNVILLIDQHEMKCKDCV-HLLKIKKTFCLCKRLTELKDNHCEQLRVKI 350
DG+ + K L E KD ++ + KK + + ++ K L+
Sbjct: 495 DGEKSGTVSSRKKPALKATSDE---KDSFSNITREKKDGEISRTVSSQKP---PALKATS 548
Query: 351 RKLKNKASVL-QKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKV 409
+ + S+ +++ EK S + L+ ++ I + KK +
Sbjct: 549 DEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHK 608
Query: 410 REKLRITEEQ-------------YRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDE 456
+ L+ T ++ +I V+ +PALK+ + + N ++ + +
Sbjct: 609 QPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQ 668
Query: 457 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLA 516
+ + +L + ++KD++ N E +KD +I Q ALK +
Sbjct: 669 SGTVSSQKQLAWKATS---VKKDSVSNIATE---IKDGQIRGTVSSQRQPALKATGDE-K 721
Query: 517 ETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKR 576
++++ + ++ T + Q++S Q++ + + + + +S +
Sbjct: 722 DSVSNIAREIKDGEKSGT-----VSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYP 776
Query: 577 DQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFE 636
+ + T+ EN NS VL + ++ ++ E +L E +++ +E
Sbjct: 777 ENLPTLKATI-------ENKNS-VLNTATKMKDVQTS-TPAEQDLEMASEGEQKRLEEYE 827
Query: 637 HVQSELKQKQSQMKDIEKMYKSGYNTME---------------------KC------IEK 669
+ Q ++K + D++ + +S E KC ++
Sbjct: 828 NNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKI 887
Query: 670 QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEED 729
++ FC K+ L + R K + +Q R + E ++++ + L LE++
Sbjct: 888 KKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEK-EEIKSQLKHETLELEKE 946
Query: 730 NKMLVNELTHSKEKECQYEK--EKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT 787
L + K+K E+ +K ++ + + Q + + TK + A
Sbjct: 947 LCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIE-----ADVTKPIKPALKSAEV 1001
Query: 788 YLENGMQDSRK--KLDQMRSQFQE---IQDQLTATIRCTKEMEGDAQKLEVENVMMRKII 842
L+ G +S + + D+ E +QD++ A +R K+ + Q LE + + +I+
Sbjct: 1002 ELKTGGNNSNQVSETDEKEDLLHENRLMQDEI-ARLRLEKDTIKN-QNLEKKYLKDFEIV 1059
Query: 843 KKQDEQIER 851
K++ E +++
Sbjct: 1060 KRKHEDLQK 1068
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/71 (50%), Positives = 42/71 (59%)
Query: 64 ATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV 123
A E S VSSQKQPALK TSDK DSVSN TEIKD Q+SGTV + +
Sbjct: 8 AASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLY 67
Query: 124 KKDSVSNIATE 134
+ D+V+ TE
Sbjct: 68 RPDAVAQPVTE 78
Score = 59.3 bits (142), Expect = 1e-08
Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 2/96 (2%)
Query: 42 VSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEI 101
VSS KQPALK TSDK +SV N ATE KDEQ SGTV + L + + D+V+ TE
Sbjct: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79
Query: 102 KDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKD 137
+ +S +S P K S + S+ ++ +++
Sbjct: 80 EFALESEIISKLYIPKRKIISPR--SIEDVLPPVEE 113
Score = 54.3 bits (129), Expect = 5e-07
Identities = 27/37 (72%), Positives = 30/37 (81%)
Query: 144 VSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSP 180
VSSQ+QPALK T D+ DSVSN A EIKD +KSGTV P
Sbjct: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLP 56
Score = 52.8 bits (125), Expect = 1e-06
Identities = 35/85 (41%), Positives = 46/85 (54%)
Query: 110 VSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREI 169
VSSQKQPA K TS K DSVSN ATEIKD Q GTV + L + D+V+ E
Sbjct: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79
Query: 170 KDGEKSGTVSPQKQSAQKVIFKKKV 194
+ +S +S +K+I + +
Sbjct: 80 EFALESEIISKLYIPKRKIISPRSI 104
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 1608 bits (4163), Expect = 0.0
Identities = 827/862 (95%), Positives = 842/862 (97%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VS E+P GLKAT DEKDS+LNIARGKK GEKTRRVSSHKQP+LKATSDKE+SVPNMATE
Sbjct: 260 TVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATE 319
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
TKDEQISGTVS QKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD
Sbjct: 320 TKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 379
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SVSNIATEIKDGQIRGTVSSQR+PALK TGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ
Sbjct: 380 SVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 439
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
KVIFKKKVSLLNIATRITGG KSGTEYPENL TLKATIENK+SVLNTATKMK+VQTSTPA
Sbjct: 440 KVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPA 499
Query: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 306
EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI
Sbjct: 500 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 559
Query: 307 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE 366
LLIDQHEMKCKDCVHLLKIK TFCL KRL +LKDNHCEQLRVKIRKLKNKASVLQKR+SE
Sbjct: 560 LLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISE 619
Query: 367 KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 426
KEEIKSQLKHE LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV
Sbjct: 620 KEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 679
Query: 427 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 486
TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL
Sbjct: 680 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 739
Query: 487 EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES 546
EKKYLKDFEIVKRKHEDLQKALKRN ETLA+TIACYSGQLAALTDENTTLRSKLEKQRES
Sbjct: 740 EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRES 799
Query: 547 GQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQ 606
QRLETEMQSYRCRLNAA CDHDQSHSSKRDQELAFQGTVDKC HLQENLNSHVLILSLQ
Sbjct: 800 RQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQ 859
Query: 607 LSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 666
LSKAESK RVL+TELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC
Sbjct: 860 LSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 919
Query: 667 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 726
IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARV+NLQAECRKHRLLL
Sbjct: 920 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 979
Query: 727 EEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC 786
EEDNKMLVNEL HSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC
Sbjct: 980 EEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC 1039
Query: 787 TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQD 846
TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGD QKLEVE+VMMRKIIKKQD
Sbjct: 1040 TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQD 1099
Query: 847 EQIERFEKILQHSSLMLQVFES 868
+QIER EKILQHSSLMLQVFES
Sbjct: 1100 DQIERLEKILQHSSLMLQVFES 1121
Score = 243 bits (621), Expect = 4e-64
Identities = 258/872 (29%), Positives = 383/872 (43%), Gaps = 132/872 (15%)
Query: 3 PFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPN 62
P +VSS+K KATSDEKDSV NIA K G+++ VS KQ A K K+ S+ N
Sbjct: 52 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLN 111
Query: 63 MATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATS 122
+AT SGTVSSQKQPA K SDK DS N TEIKDG Q GTVSSQKQ A KAT+
Sbjct: 112 IATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATT 171
Query: 123 VKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 182
++ SVSNIATEIKDG+ GTVSSQ++PALKAT DEKDS SNI RE KDGE S TVS QK
Sbjct: 172 DEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 231
Query: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 242
A K K+ S+LNIA G KS T E P LKAT + K+S+LN A KD
Sbjct: 232 PPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKD--- 288
Query: 243 STPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNC 302
GE+ R + QP +K D + ++ ++ G C
Sbjct: 289 -------------GEKTR-RVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQ 334
Query: 303 KNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQK 362
+ D+ KD V + TE+KD ++ KA+ ++K
Sbjct: 335 PALKATSDK-----KDSVSNIP-----------TEIKDGQQSGTVSSQKQPAWKATSVKK 378
Query: 363 RLSEK--EEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVR--EKLRITEE 418
EIK T+ ++ R A++ ++ +V + ++++ EK
Sbjct: 379 DSVSNIATEIKDGQIRGTVSSQR-----RPALKTTGDEKDSVSNIAREIKDGEKSGTVSP 433
Query: 419 QYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEK 478
Q + V K +L + + GG + + E LR K
Sbjct: 434 QKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPE-------------------NLRTLK 474
Query: 479 DTIKNQ----NLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENT 534
TI+N+ N K +K+ + +DL+ A + ++ L E Y + ++
Sbjct: 475 ATIENKDSVLNTATK-MKEVQTSTPAEQDLEMASEGEQKRLEE----YENNQPQVKNQIH 529
Query: 535 TLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQE 594
+ R L+ +S Q + + S C + DQ +D C HL +
Sbjct: 530 S-RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKD-----------CVHLLK 577
Query: 595 NLNSHVL---ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKD 651
N+ L ++ L+ + E +L LK KA V + SE ++ +SQ+K
Sbjct: 578 IKNTFCLWKRLIKLKDNHCE--------QLRVKIRKLKNKASVLQKRISEKEEIKSQLK- 628
Query: 652 IEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKA-----ILNIQA 706
+ +E ++ C L+ +QQ+ RN + +K I Q
Sbjct: 629 ------------HEILELEKELCSLR---FAIQQEKKKRRNVEELHQKVREKLRITEEQY 673
Query: 707 RCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKE-CQYEKEKAEREVAVRQLQQKR 765
R +A V K + + N+++ + EKE +E + E+A +L+ ++
Sbjct: 674 RIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIA--RLRLEK 731
Query: 766 DDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEME 825
D + N+ K L D + ++K + ++ + + L TI C
Sbjct: 732 DTIKNQNLEKKYLKD------------FEIVKRKHEDLQKALKRNGETLAKTIAC---YS 776
Query: 826 GDAQKLEVENVMMRKIIKKQDEQIERFEKILQ 857
G L EN +R ++KQ E +R E +Q
Sbjct: 777 GQLAALTDENTTLRSKLEKQRESRQRLETEMQ 808
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 1505 bits (3896), Expect = 0.0
Identities = 788/887 (88%), Positives = 810/887 (91%), Gaps = 26/887 (2%)
Query: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
VSS+KP LK TSDE+DSVL IAR K GEK+R VSS K P LKATSD+++SV N+A
Sbjct: 638 VSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGK 697
Query: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
KD + + TVSS KQPALKA DK+DSV N+ TE KD Q SGTVS QKQPA KATS KKDS
Sbjct: 698 KDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDS 757
Query: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGT---------- 177
VSNI TEIKDGQ GTVSSQ+QPA KAT +KDSVSNIA EIKDG+ GT
Sbjct: 758 VSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVM 817
Query: 178 ----------------VSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLK 221
VSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLK
Sbjct: 818 FDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLK 877
Query: 222 ATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDL 281
ATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDL
Sbjct: 878 ATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDL 937
Query: 282 DDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDN 341
DDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK TFCL KRL +LKDN
Sbjct: 938 DDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDN 997
Query: 342 HCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRN 401
HCEQLRVKIRKLKNKASVLQKR+SEKEEIKSQLKHE LELEKELCSLRFAIQQEKKKRRN
Sbjct: 998 HCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRN 1057
Query: 402 VEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLL 461
VEE+HQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLL
Sbjct: 1058 VEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLL 1117
Query: 462 HENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIAC 521
HENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRN ETLA+TIAC
Sbjct: 1118 HENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIAC 1177
Query: 522 YSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELA 581
YSGQLAALTDENTTLRSKLEKQRES QRLETEMQSY CRLNAA CDHDQSHSSKRDQELA
Sbjct: 1178 YSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELA 1237
Query: 582 FQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSE 641
FQGTVDKC HLQENLNSHVLILSLQLSKAESK RVL+TELHYTGEALKEKALVFEHVQSE
Sbjct: 1238 FQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSE 1297
Query: 642 LKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAI 701
LKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAI
Sbjct: 1298 LKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAI 1357
Query: 702 LNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQL 761
LNIQARCDARV+NLQAECRKHRLLLEEDNKMLVNEL HSKEKECQYEKEKAEREVAVRQL
Sbjct: 1358 LNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQL 1417
Query: 762 QQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCT 821
QQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCT
Sbjct: 1418 QQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCT 1477
Query: 822 KEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVFES 868
KEMEGD QKLEVE+VMMRKIIKKQD+QIER EKILQHSSLMLQVFES
Sbjct: 1478 KEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 1524
Score = 248 bits (634), Expect = 1e-65
Identities = 258/900 (28%), Positives = 412/900 (45%), Gaps = 102/900 (11%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+K KATSD+ DS LNIA K G + VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 365 TVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 424
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD + SGTVSSQKQPALKAT+D+KDSVSNI TEIKDG++SGTVSSQK PA ATS ++
Sbjct: 425 IKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEG 484
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SV +IA E KDG+ TVSS+++PALKAT DEKDS SNI R KDGE S VS QK
Sbjct: 485 SVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 544
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
K ++ S+L IA G KS T E P LKA+ K+SVLN A KD + +
Sbjct: 545 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRV 604
Query: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 306
+ + E + + N + K+ SR + + S++ DS
Sbjct: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDS--------- 655
Query: 307 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLR-----VKIRKLKNKASVLQ 361
+L E K + + +K L K ++ KD+ R K R + +
Sbjct: 656 VLGIARENKDGEKSRTVSSEKPPGL-KATSDEKDSVLNIARGKKDGEKTRTVSSPKQPAL 714
Query: 362 KRLSEKEEIKSQLKHETLELE---KELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEE 418
K + +KE+ + E + + C + A++ K+ +V + ++++ +
Sbjct: 715 KAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQ---- 770
Query: 419 QYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKED--LLHENRLMQDEIARLRL 476
V+ +PA K+ V+ + N + ++ + + L + +M D+I
Sbjct: 771 ----SGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIE---- 822
Query: 477 EKDTIKNQNL---EKKYLKDFEIVKRKHEDLQKALK------------RNEETLAETIAC 521
EK T N++ +K I K+K L A + N TL TI
Sbjct: 823 EKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIEN 882
Query: 522 YSGQLAALT-----DENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKR 576
+ L T +T LE E Q+ E ++ + ++ + D +
Sbjct: 883 KNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQ 942
Query: 577 DQELAFQGTVDKCCHLQENLNSHVLILS---------LQLSKAESKF----RVLETELHY 623
+ + CC N + +L++ + L K ++ F R+++ + ++
Sbjct: 943 SSQTVSEDGDSLCC----NCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNH 998
Query: 624 TGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLL 683
E L+ K ++ S L+++ S+ ++I+ K + +E ++ C L+ +
Sbjct: 999 C-EQLRVKIRKLKNKASVLQKRISEKEEIKSQLK------HEILELEKELCSLR---FAI 1048
Query: 684 QQQLDDARNKADNQEKA-----ILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELT 738
QQ+ RN + +K I Q R +A V K + + N+++
Sbjct: 1049 QQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVS 1108
Query: 739 HSKEKE-CQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSR 797
+ EKE +E + E+A +L+ ++D + N+ K L D + +
Sbjct: 1109 ETDEKEDLLHENRLMQDEIA--RLRLEKDTIKNQNLEKKYLKD------------FEIVK 1154
Query: 798 KKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQ 857
+K + ++ + + L TI C G L EN +R ++KQ E +R E +Q
Sbjct: 1155 RKHEDLQKALKRNGETLAKTIAC---YSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 1211
Score = 246 bits (627), Expect = 9e-65
Identities = 255/887 (28%), Positives = 397/887 (44%), Gaps = 104/887 (11%)
Query: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
VSS+K KATSD+KDSV NIA K G + VSS KQPA KATSD+++SV N+ATE
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
Query: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
K Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQPA KATS K DS
Sbjct: 324 KKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383
Query: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
NIATEIKDG GTVSSQ+QPALKAT DE+DSVSNIA EIKDGEKSGTVS QKQ A K
Sbjct: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
Query: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247
+K S+ NIAT I G KSGT + P L AT + + SVL+ A + KD + S
Sbjct: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503
Query: 248 QDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVIL 307
+ A + + + N K+ SR + + S++ DS +L
Sbjct: 504 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDS--------VL 555
Query: 308 LIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ----KR 363
I + + K ++ LK + E K SVL K+
Sbjct: 556 GIARENKDGE--------KSRTVSSEKPPGLKASSAE-----------KDSVLNIARGKK 596
Query: 364 LSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIE 423
EK + S K +LE + I +EKK ++ + L+ T ++
Sbjct: 597 DGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 656
Query: 424 ADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKN 483
+ + K KS V + + +DEK+ +L+ IAR + KD K
Sbjct: 657 LGIARENKDGEKSRTV---SSEKPPGLKATSDEKDSVLN--------IARGK--KDGEKT 703
Query: 484 QNLEKKYLKDFEIVKRKHEDL-QKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEK 542
+ + + + K + + A ++ +E ++ T++C T +
Sbjct: 704 RTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSD---------- 753
Query: 543 QRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLI 602
+++S + TE++ D QS + ++ A++ T K V
Sbjct: 754 KKDSVSNIPTEIK-----------DGQQSGTVSSQKQPAWKATSVK--------KDSVSN 794
Query: 603 LSLQLSKAESK-FRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYN 661
++ ++ + + +LE + + ++EK QKQS K I K S N
Sbjct: 795 IATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLN 854
Query: 662 TMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVE-NLQAECR 720
+ + + + L+ +++ +N N + ++Q A + + +E
Sbjct: 855 IATRITGGWKSGTEYPENLPTLKATIEN-KNSVLNTATKMKDVQTSTPAEQDLEMASEGE 913
Query: 721 KHRLLLEEDNKMLVNELTHSKE------KECQYEKEKAER--------EVAVRQLQQKRD 766
+ RL E+N+ V HS++ + Q E + + + Q + K
Sbjct: 914 QKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCK 973
Query: 767 D------VLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRC 820
D + N K L+ HC L R K+ +++++ +Q +++
Sbjct: 974 DCVHLLKIKNTFCLWKRLIKLKDNHCEQL-------RVKIRKLKNKASVLQKRISEKEEI 1026
Query: 821 TKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVFE 867
+++ + +LE E +R I+++ ++ E++ Q L++ E
Sbjct: 1027 KSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITE 1073
Score = 71.2 bits (173), Expect = 4e-12
Identities = 51/138 (36%), Positives = 64/138 (46%)
Query: 106 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNI 165
Q VS ++ P + T +D +S D SS+R P T E D S
Sbjct: 192 QKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKA 251
Query: 166 AREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIE 225
A KD G VS QKQ A+K K S+ NIAT I G SGT + P KAT +
Sbjct: 252 AMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSD 311
Query: 226 NKNSVLNTATKMKDVQTS 243
K+SV N AT++K Q S
Sbjct: 312 EKDSVSNIATEIKKGQQS 329
Score = 61.6 bits (148), Expect = 3e-09
Identities = 82/306 (26%), Positives = 117/306 (38%), Gaps = 76/306 (24%)
Query: 42 VSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEI 101
VSS KQPALK TSDK++SV N ATE KDEQ SGTV + L + + D+V+ TE
Sbjct: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
Query: 102 KDGQQSGTVSSQKQPAWK----------------------------ATSVKKDSVSNIAT 133
+ +S +S P K A V KD + +
Sbjct: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
Query: 134 EIKDGQI--RGTVSSQRQPALKAT-GDEKDSVSNIAREIKDGEKSGTVSP---QKQSA-- 185
I + R T+S Q L A G +K N+ E ++ +K G P QK +
Sbjct: 140 NISEPYFTNRRTISQQSAENLDAACGIDKTENGNMF-EDQNVDKEGKALPATGQKANVSP 198
Query: 186 -QKVIFKKKV-SLLNIATRITGGWKSGTEYPEN--------------------------- 216
Q +F V +I+TR GG S T E+
Sbjct: 199 EQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDS 258
Query: 217 ----------LPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYEN 266
P KAT ++K+SV N AT++K+ S + A + + N
Sbjct: 259 PPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 318
Query: 267 NQPQVK 272
++K
Sbjct: 319 IATEIK 324
Score = 61.2 bits (147), Expect = 4e-09
Identities = 36/71 (50%), Positives = 42/71 (59%)
Query: 64 ATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV 123
A E S VSSQKQPALK TSDK DSVSN TEIKD Q+SGTV + +
Sbjct: 8 AASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLY 67
Query: 124 KKDSVSNIATE 134
+ D+V+ TE
Sbjct: 68 RPDAVAQPVTE 78
>gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 475
Score = 828 bits (2138), Expect = 0.0
Identities = 421/443 (95%), Positives = 431/443 (97%)
Query: 318 DCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE 377
DCVHLLKIK TFCL KRL +LKDNHCEQLRVKIRKLKNKASVLQKR+SEKEEIKSQLKHE
Sbjct: 24 DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 83
Query: 378 TLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA 437
LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA
Sbjct: 84 ILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA 143
Query: 438 EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIV 497
EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRL+ DTIKNQNLEKKYLKDFEIV
Sbjct: 144 EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLDTDTIKNQNLEKKYLKDFEIV 203
Query: 498 KRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSY 557
KRKHEDLQKALKRN ETLA+TIACYSGQLAALTDENTTLRSKLEKQRES QRLETEMQSY
Sbjct: 204 KRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY 263
Query: 558 RCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVL 617
CRLNAA CDHDQSHSSKRDQELAFQGTVDKC HLQENLNSHVLILSLQLSKAESK RVL
Sbjct: 264 HCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL 323
Query: 618 ETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK 677
+TELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK
Sbjct: 324 KTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK 383
Query: 678 KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNEL 737
KQNMLLQQQLDDARNKADNQEKAILNIQARCDARV+NLQAECRKHRLLLEEDNKMLVNEL
Sbjct: 384 KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNEL 443
Query: 738 THSKEKECQYEKEKAEREVAVRQ 760
HSKEKECQYEKEKAEREV++++
Sbjct: 444 NHSKEKECQYEKEKAEREVSIKK 466
Score = 38.1 bits (87), Expect = 0.036
Identities = 62/281 (22%), Positives = 110/281 (39%), Gaps = 50/281 (17%)
Query: 586 VDKCCHLQENLNSHVL---ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSEL 642
V C HL + N+ L ++ L+ + E +L LK KA V + SE
Sbjct: 22 VTDCVHLLKIKNTFCLWKRLIKLKDNHCE--------QLRVKIRKLKNKASVLQKRISEK 73
Query: 643 KQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKA-- 700
++ +SQ+K + +E ++ C L+ +QQ+ RN + +K
Sbjct: 74 EEIKSQLK-------------HEILELEKELCSLR---FAIQQEKKKRRNVEELHQKVRE 117
Query: 701 ---ILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKE-CQYEKEKAEREV 756
I Q R +A V K + + N+++ + EKE +E + E+
Sbjct: 118 KLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEI 177
Query: 757 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 816
A +L+ D + N+ K L D + ++K + ++ + + L
Sbjct: 178 A--RLRLDTDTIKNQNLEKKYLKD------------FEIVKRKHEDLQKALKRNGETLAK 223
Query: 817 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQ 857
TI C G L EN +R ++KQ E +R E +Q
Sbjct: 224 TIAC---YSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 261
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 570 bits (1468), Expect = e-162
Identities = 346/851 (40%), Positives = 506/851 (59%), Gaps = 81/851 (9%)
Query: 77 SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGT------VSSQKQPAWKATSVKKDSVSN 130
S ++ LK T + KDSV N +KD Q S V+S+++ + + + V
Sbjct: 489 SPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSENNQPQVEE 548
Query: 131 IATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIF 190
+ ++ ++ VS+ ++ D + ++ K GE P+K++ +
Sbjct: 549 ERKKHRNNEME--VSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKENKEYASS 606
Query: 191 KKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDL 250
+ + + + + E + ++ + + K S+L D +S L
Sbjct: 607 GPALQMKEVKS-------TEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSS------L 653
Query: 251 EMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLID 310
E E + ++ N + +VKNQI S DD+DD+ QSS+T SED + + KN +LLI+
Sbjct: 654 SEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIE 713
Query: 311 QHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEI 370
Q M+CKD V LLKI+ C+RL ELK NHCE L VKI+K+++K +VLQ+ LSE +EI
Sbjct: 714 QLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEI 773
Query: 371 KSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPI 430
KSQL+H+ +E E+ELCSLRF++ QE++KRRN + L++K+RE+LR EEQYR E +V + +
Sbjct: 774 KSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQL 833
Query: 431 KPALKSAEVELKTGGNNSNQVSET------------------------------------ 454
+ +L++ E+EL+T +N NQV +
Sbjct: 834 ELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQ 893
Query: 455 -----------DEKEDLLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRKH 501
+E++DL H+N ++Q+EIA LRLE DTIKNQN EKK +D +IVK K+
Sbjct: 894 KKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKN 953
Query: 502 EDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRL 561
EDLQK +K+NEETL +TI+ Y+G+L+ LT EN L SKLE +++S +RLE E++SY RL
Sbjct: 954 EDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRL 1013
Query: 562 NAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESKF 614
AA+ D DQS +SKR+ ELAFQ D+C LQ+ +N V ILS QL K ESK
Sbjct: 1014 AAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKL 1073
Query: 615 RVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ---- 670
LE E H+T +AL+EK L E VQ +L Q Q QMK++E+ Y++ + K I KQ
Sbjct: 1074 NSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVE 1133
Query: 671 ERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDN 730
ER QL+ +NMLL+QQLDDA NKADN+EK ++NIQ + A V+ LQAE K LLLEE N
Sbjct: 1134 ERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERN 1193
Query: 731 KMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLE 790
K L++E H KE++ QYE EKAEREV VRQLQQ+ D L K S ++A L+ +SR+ LE
Sbjct: 1194 KELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLE 1253
Query: 791 NGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIE 850
+ QD +KKL Q+R+Q QE QD+ T +RC ++M+ QKLE +N ++ +KKQ ++IE
Sbjct: 1254 DETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIE 1313
Query: 851 RFEKILQHSSL 861
+K L +++L
Sbjct: 1314 ELQKNLLNANL 1324
Score = 107 bits (266), Expect = 6e-23
Identities = 173/726 (23%), Positives = 302/726 (41%), Gaps = 116/726 (15%)
Query: 201 TRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKR 260
TR G + E PE LK TIE K+SV N A MKDVQTS AE DLE+ASE EQ+R
Sbjct: 477 TRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQER 536
Query: 261 LEEYENNQPQVKNQ--------------IH--------SRDDLDDIIQSSQTVSEDGDSL 298
E ENNQPQV+ + IH DD D +IQ ++ D
Sbjct: 537 -EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQF 595
Query: 299 -------------CCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQ 345
K V ++ + K+ V+ K L L ++ D+
Sbjct: 596 PRKENKEYASSGPALQMKEV-KSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDS--- 651
Query: 346 LRVKIRKL-KNKASVLQKRLSEKEEIKSQLKH--------ETLELEKELCSLRFAIQQEK 396
+ ++ +++ +K +EK ++K+Q++ ++ E E C L + K
Sbjct: 652 ---SLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHS--SYK 706
Query: 397 KKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNN--------- 447
+E+L + ++ + + + Q +A ++ LK EL T
Sbjct: 707 NFMLLIEQLGMECKDSVSLLKIQ---DAALSCERLLELKKNHCELLTVKIKKMEDKVNVL 763
Query: 448 SNQVSETDE-KEDLLHENRLMQDEIARLR--LEKDTIKNQNLEKKYLKDFEIVKRKHEDL 504
++SET E K L H+ + E+ LR L ++ K +N + Y K E ++RK E
Sbjct: 764 QRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQY 823
Query: 505 QKALKRNEETLAETIACYSGQLAALTDENTTLRSKLE---KQRESGQRLETEMQSYRCRL 561
+K ++ ++ L L E T++S L ++R QR + Q+ R
Sbjct: 824 RKEVEVKQQ--------LELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQ 875
Query: 562 NAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETEL 621
+ L +H S +++ E+A + + H E LS + S + + +L E+
Sbjct: 876 DGILTNH---LSKQKEIEMAQKKMNSENSHSHEEEKD----LSHKNSMLQEEIAMLRLEI 928
Query: 622 HYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE-RFCQLKKQN 680
+EK + +LK + + +D++K K T+ + I + R L +N
Sbjct: 929 DTIKNQNQEKE---KKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAEN 985
Query: 681 MLLQQQLDDARNKADNQEKAILNIQARCDARVENL-QAECRKHRLLLEEDNKMLVNELTH 739
+L +L++ + + E + + +R A + + Q+E K L EL
Sbjct: 986 AMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKREL-----------ELAF 1034
Query: 740 SKEK-ECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRK 798
+ + EC ++K +V+ L+ + + + T++ L++ LE +R
Sbjct: 1035 QRARDECSRLQDKMNFDVS--NLKDNNEILSQQLFKTESKLNS-------LEIEFHHTRD 1085
Query: 799 KLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQH 858
L + + +Q L+ T KEME QK + E V + K I KQ+ ER ++
Sbjct: 1086 ALREKTLGLERVQKDLSQTQCQMKEME---QKYQNEQVKVNKYIGKQESVEERLSQLQSE 1142
Query: 859 SSLMLQ 864
+ L+ Q
Sbjct: 1143 NMLLRQ 1148
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 546 bits (1408), Expect = e-155
Identities = 329/692 (47%), Positives = 439/692 (63%), Gaps = 37/692 (5%)
Query: 127 SVSNIATEIKDGQIRGTVS----SQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 182
+ + A K IRG +S ++R+ +L+ + E+D E + E + PQ
Sbjct: 239 TAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298
Query: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 242
+ K KK + ++ + Y +++ L I+N+ K
Sbjct: 299 EEKMKKCRNKK---MEVSRNVHAD--DSDNYNDDVDELIHKIKNR----------KPDNH 343
Query: 243 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 301
+P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + +
Sbjct: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397
Query: 302 CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ 361
+N +LLI Q M+CKD V L K K C R E + +CE+L+VK +K+KN SVLQ
Sbjct: 398 DENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457
Query: 362 KRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 421
K LSE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR
Sbjct: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517
Query: 422 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 480
+ +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT
Sbjct: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577
Query: 481 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRS 538
IK+QN E KY KD EI+K +EDL+K LKRNEETL +TI YS +L L DENT L S
Sbjct: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637
Query: 539 KLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNS 598
+L+K+++S RLETEM+SYRCRL AALCDHDQ SSKRD +LAFQ TV++ CHLQE+ NS
Sbjct: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697
Query: 599 HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 658
H+ ILS QLSKAES LETELHY EALKEK L EH+Q L + Q +++DIE MY++
Sbjct: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757
Query: 659 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVEN 714
+EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ VE
Sbjct: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817
Query: 715 LQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSA 774
LQAECRK LEE+NK L+ E T KE++CQYEKEK EREV RQLQ++ DD LNK
Sbjct: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873
Query: 775 TKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 806
+A+L+ SS LE+ Q +KKL QMRSQ
Sbjct: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 546 bits (1408), Expect = e-155
Identities = 329/692 (47%), Positives = 439/692 (63%), Gaps = 37/692 (5%)
Query: 127 SVSNIATEIKDGQIRGTVS----SQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 182
+ + A K IRG +S ++R+ +L+ + E+D E + E + PQ
Sbjct: 239 TAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298
Query: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 242
+ K KK + ++ + Y +++ L I+N+ K
Sbjct: 299 EEKMKKCRNKK---MEVSRNVHAD--DSDNYNDDVDELIHKIKNR----------KPDNH 343
Query: 243 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 301
+P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + +
Sbjct: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397
Query: 302 CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ 361
+N +LLI Q M+CKD V L K K C R E + +CE+L+VK +K+KN SVLQ
Sbjct: 398 DENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457
Query: 362 KRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 421
K LSE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR
Sbjct: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517
Query: 422 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 480
+ +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT
Sbjct: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577
Query: 481 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRS 538
IK+QN E KY KD EI+K +EDL+K LKRNEETL +TI YS +L L DENT L S
Sbjct: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637
Query: 539 KLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNS 598
+L+K+++S RLETEM+SYRCRL AALCDHDQ SSKRD +LAFQ TV++ CHLQE+ NS
Sbjct: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697
Query: 599 HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 658
H+ ILS QLSKAES LETELHY EALKEK L EH+Q L + Q +++DIE MY++
Sbjct: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757
Query: 659 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVEN 714
+EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ VE
Sbjct: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817
Query: 715 LQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSA 774
LQAECRK LEE+NK L+ E T KE++CQYEKEK EREV RQLQ++ DD LNK
Sbjct: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873
Query: 775 TKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 806
+A+L+ SS LE+ Q +KKL QMRSQ
Sbjct: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 544 bits (1402), Expect = e-154
Identities = 328/692 (47%), Positives = 438/692 (63%), Gaps = 37/692 (5%)
Query: 127 SVSNIATEIKDGQIRGTVS----SQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 182
+ + A K IRG +S ++R +L+ + E+D E + E + PQ
Sbjct: 239 TAEDYAVASKFQAIRGMISEYKANKRCKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298
Query: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 242
+ K KK + ++ + Y +++ L I+N+ K
Sbjct: 299 EEKMKKCRNKK---MEVSRNVHAD--DSDNYNDDVDELIHKIKNR----------KPDNH 343
Query: 243 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 301
+P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + +
Sbjct: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397
Query: 302 CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ 361
+N +LLI+Q M+CKD V L K K C R E + +CE+L+VK +K+KN SVLQ
Sbjct: 398 DENFMLLIEQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457
Query: 362 KRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 421
K LSE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR
Sbjct: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517
Query: 422 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 480
+ +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT
Sbjct: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577
Query: 481 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRS 538
IK+QN E KY KD EI+K +EDL+K LKRNEE L +TI YS +L L DENT L S
Sbjct: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNS 637
Query: 539 KLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNS 598
+L+K+++S RLETEM+SYRCRL AALCDHDQ SSKRD +LAFQ TV++ CHLQE+ NS
Sbjct: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697
Query: 599 HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 658
H+ ILS QLSKAES LETELHY EALKEK L EH+Q L + Q +++DIE MY++
Sbjct: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757
Query: 659 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVEN 714
+EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ VE
Sbjct: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817
Query: 715 LQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSA 774
LQAECRK LEE+NK L+ E T KE++CQYEKEK EREV RQLQ++ DD LNK
Sbjct: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873
Query: 775 TKALLDASSRHCTYLENGMQDSRKKLDQMRSQ 806
+A+L+ SS LE+ Q +KKL QMRSQ
Sbjct: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 378 bits (970), Expect = e-104
Identities = 251/675 (37%), Positives = 375/675 (55%), Gaps = 79/675 (11%)
Query: 248 QDLEMASEGEQKR-LEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 306
Q + GE R ++ N + +VKNQI+ D D ++ S+ SED + +N +
Sbjct: 560 QQIPRKENGEHDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFM 619
Query: 307 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE 366
LLI+Q M+ KD L +I+ TFCLC+ L +LK+NHC+QL VK+++++N SVLQ LSE
Sbjct: 620 LLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSE 679
Query: 367 KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 426
++ K QL+ + +E EKEL LR A++QE +++RN + L+ K E+LRI EE+ +
Sbjct: 680 TKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVET 739
Query: 427 TKPIKPALKSAEVELKTGGNN--------------------------------------- 447
+ +K L+ EL+T NN
Sbjct: 740 KQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMA 799
Query: 448 ----SNQVSETDEKE-DLLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRK 500
++++S +KE DL HE+ ++Q+EIA LRLE DTIKNQN EKKY +D E VK K
Sbjct: 800 RKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEK 859
Query: 501 HEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCR 560
+++LQK +K NEETL ETI YSGQL LT EN L S+LE +++ +RLE EM+SYRCR
Sbjct: 860 NDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCR 919
Query: 561 LNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQE-------NLNSHVLILSLQLSKAESK 613
L AA+ D DQS ++ RD +L FQ T + L + L + ILS +LS AESK
Sbjct: 920 LAAAVRDCDQSQTA-RDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESK 978
Query: 614 FRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ--- 670
L+ +LH T +AL ++L+ E VQ +L Q Q Q K+ E+MY+ + ++K I KQ
Sbjct: 979 INSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESV 1038
Query: 671 -ERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEED 729
ER QL+ +NMLL+QQLDDA KA++QEK IQ + + +NLQAE K L L+E
Sbjct: 1039 EERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEK 1098
Query: 730 NKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQ----------KRDDVLNKGSATKALL 779
NK L++E H KE+ Q EKEKA R++ + + Q+ ++VL T +
Sbjct: 1099 NKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQL-QQTLFSM 1157
Query: 780 DASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMR 839
A + C L+ + ++++ ++S + + + + KL +E +
Sbjct: 1158 KAIQKQCETLQKNKKQLKQEVVNLKSYMER---------NMLERGKAEWHKLLIEERARK 1208
Query: 840 KIIKKQDEQIERFEK 854
+I +K +E I +K
Sbjct: 1209 EIEEKLNEAILTLQK 1223
Score = 79.0 bits (193), Expect = 2e-14
Identities = 166/839 (19%), Positives = 324/839 (38%), Gaps = 149/839 (17%)
Query: 124 KKDSVSNIATEIKDGQIRGTVSSQRQPALKATG-DEKDSVSNIAREIKDGEKSGTVSPQK 182
+K S+ + E K+ Q ++ P T D ++ +K +K +VSP
Sbjct: 112 RKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVDDKCPSVSPSM 171
Query: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTA-TKMKDVQ 241
Q K++ +N+ R E + T + +++ + +++ + +
Sbjct: 172 PENQSAT--KELGQMNLTER------------EKMDTGVVLLSGNDTLHDLCQSQLPENK 217
Query: 242 TSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ---IHSRDDLDDI--------IQSSQT 290
S AEQD E+ SE EQ+RL+ EN QPQ +Q + D +DI +Q S+
Sbjct: 218 ESKEAEQDSELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277
Query: 291 VSEDGDSLCCNCKNVI-LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVK 349
+ + L KN + L+I++ + + + KI C L DN VK
Sbjct: 278 MWIEQGKL--EWKNQLKLVINELKQRFGEIYEKYKIP----ACPEEEPLLDNSTRGTDVK 331
Query: 350 IRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKE--------------------LC--S 387
++ + EI + ET +KE +C S
Sbjct: 332 DIPFNLTNNIPGCEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSS 391
Query: 388 LRFAIQQEK---------------------------KKRRNVEELHQKVRE----KLRIT 416
+F + + K KK RN E + +++E L++T
Sbjct: 392 SKFHLHENKLDCDNDNKPGIGHIFSTDKNFHNDASTKKARNPEVVMVEMKEDQEFDLQMT 451
Query: 417 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRL 476
+ + + +LK L + +S++ SE E+L + + ++E+ L
Sbjct: 452 KNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEE 511
Query: 477 EKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK---------------RNEETLAETIAC 521
E +K ++++ KD E KH L N++ +
Sbjct: 512 EFLALKKEDVQLH--KDVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQIPRKENGE 569
Query: 522 YSGQLAALTDENTTLRSKLEKQRESGQRLE-TEMQSYRCRLNAALCDH-----DQSHSSK 575
+ ++E +++++ + + +E +E+ S C L+ ++ ++ +Q
Sbjct: 570 HDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEY 629
Query: 576 RDQEL--AFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEA---LKE 630
+D Q T C HL + N+H L+++L + E+ VL+ EL T + L+
Sbjct: 630 KDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLEL 689
Query: 631 KALVFE----HVQSELKQKQSQMKDIEKMYKSGYNTM----EKCIEKQERFCQLKKQNML 682
+ + +E ++ LKQ+ + ++ + +Y + E+C + E QLK
Sbjct: 690 QKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRR 749
Query: 683 LQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKE 742
L ++L RN D L +Q R DA + +L E+D ++L +++ SK+
Sbjct: 750 LVKELRTVRNNLD------LVVQERNDA----------QKQLSEEQDARILQDQILTSKQ 793
Query: 743 KECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQ 802
KE + ++K E++ R QK D+ ++ + + ++N + KK +
Sbjct: 794 KELEMARKKMNSEISHR--HQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFE 851
Query: 803 MRSQFQEIQDQLTATIRCTKE--------MEGDAQKLEVENVMMRKIIKKQDEQIERFE 853
+E D L I+ +E G L EN ++ ++ + ER E
Sbjct: 852 DIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLE 910
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 349 bits (896), Expect = 6e-96
Identities = 271/793 (34%), Positives = 414/793 (52%), Gaps = 84/793 (10%)
Query: 12 KPSGLKATSDEKDSVLNIARGKKHGEKTRRV-----SSHKQP-----------ALKATSD 55
KPS + ++ + SV N A K+ E+T R S KQ + S
Sbjct: 582 KPSAFEPATEMQKSVPNKALELKN-EQTLRADEILPSESKQKDYEENSWDTESLCETVSQ 640
Query: 56 KENSVPNMATETKDEQISGTV--SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQ 113
K+ +P A + + ++I+G + S K LKA K S+ E+ D Q +
Sbjct: 641 KDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPE 700
Query: 114 KQPAWKATSVKKDSVSNIATEIKDGQ------IRGTVSSQRQ--------PALKATGDEK 159
K A++ + SV N A E+K+ Q I + S Q+ +L T +K
Sbjct: 701 KPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQK 760
Query: 160 DSVSNIAREIKDGEK-SGTV--SPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPEN 216
D A K+ +K +G + SP K + KVS+ A + E PE
Sbjct: 761 DVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEK 820
Query: 217 LPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIH 276
+ IE + SV N A ++K+ QT D SE +QK++EE + ++ +
Sbjct: 821 PSAFEPAIEMQKSVPNKALELKNEQT---LRADQMFPSESKQKKVEENSWDSESLRETVS 877
Query: 277 SRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLT 336
+D +C +D+ K +D L KI T C+R
Sbjct: 878 QKD------------------VCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERAR 919
Query: 337 ELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEK 396
EL+ +HCEQ K+ ++K K VL+K+LSE +EIKSQL+++ ++ E+ELCS+R + QE+
Sbjct: 920 ELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEE 979
Query: 397 KKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDE 456
+KRRN + L++K+RE+L EEQ+R E +V + ++ AL+ ++ELK+ +N NQVS T E
Sbjct: 980 EKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHE 1039
Query: 457 KED-LLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEE 513
E+ LLHEN +++ EIA L+LE T+K+Q EK KY +D +I+K K+ +LQ LK EE
Sbjct: 1040 NENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEE 1099
Query: 514 TLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHS 573
+L + + YSGQL L ENT L SKL K+++ + LE E++S+ RL +A+ DHDQ +
Sbjct: 1100 SLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVT 1158
Query: 574 SKRDQELAFQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGE 626
S++ QE AF D C LQ +N V +L LS+A+ K + L+ L+Y G+
Sbjct: 1159 SRKSQEPAFHIAGDAC--LQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGD 1216
Query: 627 ALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNML 682
AL+E LV EH Q + ++ Q QMK+ E MY++ + + K E+QE + QL+ +NM
Sbjct: 1217 ALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMW 1276
Query: 683 LQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKE 742
LQQQL A KADN+ K ++I L+ + + H LL+E N+ + N H K
Sbjct: 1277 LQQQLVHAHKKADNKSKITIDIHF--------LERKMQHH--LLKEKNEEIFNYNNHLKN 1326
Query: 743 KECQYEKEKAERE 755
+ QYEKEKAE E
Sbjct: 1327 RIYQYEKEKAETE 1339
Score = 52.4 bits (124), Expect = 2e-06
Identities = 169/847 (19%), Positives = 333/847 (39%), Gaps = 130/847 (15%)
Query: 46 KQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 105
K+ + KA+++ + P+ + + +DE+ S S + + K +S+ EI
Sbjct: 399 KESSTKASANDQR-FPSESKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREV 457
Query: 106 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNI 165
+ +K A+K ++SV N A E+K+ Q + + P +KD N
Sbjct: 458 EE---PPKKPSAFKPAIEMQNSVPNKAFELKNEQ-----TLRADPMFPPESKQKDYEENS 509
Query: 166 AREIKDGEK-SGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATI 224
D E TVS + K +K++ +N E P LKAT
Sbjct: 510 W----DSESLCETVSQKDVCLPKATHQKEIDKINGKLE---------ESPNKDGLLKATC 556
Query: 225 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 284
K S+ A ++KD+QT A E + + N ++KN+ R D+I
Sbjct: 557 GMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTLR--ADEI 614
Query: 285 IQSS------QTVSEDGDSLC--CNCKNVILLIDQHEMKCKDCVHLLK-------IKKTF 329
+ S + S D +SLC + K+V L H+ + L+ + K
Sbjct: 615 LPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKAN 674
Query: 330 CLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLR 389
C K K ++ + K S + + E++ + ++ LEL+ E
Sbjct: 675 CGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI----EMQKSVPNKALELKNEQTLRA 730
Query: 390 FAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN 449
I + K+++ EE E L T Q DV P A E++ G
Sbjct: 731 DEILPSESKQKDYEESSWD-SESLCETVSQ----KDVCLP--KATHQKEIDKING----- 778
Query: 450 QVSETDEKEDLLHENRLMQDEIARLRLE---KDTIKNQNLEKKYLKDFEIVKRKHEDLQK 506
++ E+ + + L M+ I LE T K + EK + I +K +
Sbjct: 779 KLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKA 838
Query: 507 ALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALC 566
+NE+TL D+ SK +K E+ E+ ++ +C
Sbjct: 839 LELKNEQTLR-------------ADQMFPSESKQKKVEENSWDSESLRETVS---QKDVC 882
Query: 567 DHDQSHSSKRDQELAFQGTVDKCCHLQENLNS-HVLILSLQLSKAESKFRVLETELHYTG 625
+H + D+ G ++ L + L++ H + +L K + R +
Sbjct: 883 VPKATHQKEMDK---ISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKM------ 933
Query: 626 EALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNM-LLQ 684
E +K+K V + SE K+ +SQ+++ + ++ ++ + ++E K++N +L
Sbjct: 934 EQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEE----KRRNADILN 989
Query: 685 QQLDDARNKADNQEKAILNIQARCD--ARVENLQAECRKHRLLLEEDNKMLVNELTHSKE 742
+++ + + + Q + L ++ + + R+++++ + + L N+++H+ E
Sbjct: 990 EKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNL----------NQVSHTHE 1039
Query: 743 KE-------CQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQD 795
E C +KE A ++ + L+ + + NK Y E+ ++
Sbjct: 1040 NENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENK----------------YFED-IKI 1082
Query: 796 SRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMM-RKIIKKQDEQIERFEK 854
++K +++ + ++ LT + + G + L EN M+ K+ +KQD++I E
Sbjct: 1083 LKEKNAELQMTLKLKEESLT---KRASQYSGQLKVLIAENTMLTSKLKEKQDKEILEAEI 1139
Query: 855 ILQHSSL 861
H L
Sbjct: 1140 ESHHPRL 1146
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 315 bits (807), Expect = 1e-85
Identities = 260/790 (32%), Positives = 403/790 (51%), Gaps = 59/790 (7%)
Query: 9 SSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATETK 68
S K LK T K S+ N A K E + S K LK T ++ S+PN A E K
Sbjct: 610 SPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELK 669
Query: 69 DEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKD------GQQSGTVSSQK---QPAWK 119
D + S LK T +K S+ N E+KD Q + S QK + +W
Sbjct: 670 DRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEENSWD 729
Query: 120 ATSVKKDSVSNI-----ATEIKD-GQIRGTV--SSQRQPALKATGDEKDSVSNIAREIKD 171
S + + N AT K+ + G + S + LK T K S+ N A E+KD
Sbjct: 730 FESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKD 789
Query: 172 GEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVL 231
E + +F K + + +T++ + T+ T+ E ++
Sbjct: 790 RETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGAT-KTVTGQQERDIGII 848
Query: 232 NTATKMKDVQTSTPA---EQDLEMASEGEQKRLEEYENNQ--PQVKNQIHSRDDLDDIIQ 286
A + + + T ++D + S+ E + + +N + P+ Q + I +
Sbjct: 849 ERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEE 908
Query: 287 SSQTVS--EDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCE 344
S + S E + + N L + D L KI C+R ELK ++CE
Sbjct: 909 SPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCE 968
Query: 345 QLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEE 404
Q+ K+ + KNK VLQK LSE +EIKSQL+++ + E+ELCS+R + QE++KRRNV+
Sbjct: 969 QITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDI 1028
Query: 405 LHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHE 463
L +K+R EEQ R + +V + ++ L+ ++ELK+ +N NQVS T E E DL HE
Sbjct: 1029 LKEKIR-----PEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHE 1083
Query: 464 NRLMQDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIAC 521
N +++ EIA L+LE T+K+Q+ E KY +D +I++ K+ +LQ LK ++T+ + +
Sbjct: 1084 NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQ 1143
Query: 522 YSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELA 581
Y QL LT ENT L SKL K+++ + LETE++S+ RL +AL DHDQS +S+++QELA
Sbjct: 1144 YREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELA 1202
Query: 582 FQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKEKALV 634
F D LQ +N V +L L +A+ K + + L+Y G+ L+E ALV
Sbjct: 1203 FHSAGD--APLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALV 1260
Query: 635 FEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNMLLQQQLDDA 690
EH Q + + Q QMK E MY++ + ++K E+QE + QL+ +N L+QQL A
Sbjct: 1261 SEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYA 1320
Query: 691 RNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKE 750
K N+ K +NIQ + + ++H L E N+ + N H KE+ QYEKE
Sbjct: 1321 HKKV-NKSKVTINIQFP--------EMKMQRH---LNEKNEEVFNYGNHLKERIDQYEKE 1368
Query: 751 KAEREVAVRQ 760
KAEREV++++
Sbjct: 1369 KAEREVSIKK 1378
Score = 80.1 bits (196), Expect = 8e-15
Identities = 185/849 (21%), Positives = 319/849 (37%), Gaps = 153/849 (18%)
Query: 46 KQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 105
K A K + + +VPN A E K+EQ + + ++ S P E
Sbjct: 528 KPSAFKPAVEMQKTVPNKAFELKNEQTLRAAQMFPSESKQKDDEENSWDSESPCE----- 582
Query: 106 QSGTVSSQKQPAWKATSVKK-DSVSNIATE--IKDGQIRGTVSSQRQPALKATGDEKDSV 162
TVS + KAT K+ D++S E +KDG LK T K S+
Sbjct: 583 ---TVSQKDVYLPKATHQKEFDTLSGKLEESPVKDG------------LLKPTCGRKVSL 627
Query: 163 SNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKA 222
N A E+KD E SP K K +KVSL N A + E P+N LK
Sbjct: 628 PNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKP 687
Query: 223 TIENKNSVLNTATKMKDVQT--------STPAEQDLEMASEGEQKRLEEYENNQPQVKNQ 274
T K S+ N A ++KD +T S ++D E S + LE N +
Sbjct: 688 TCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLPKA 747
Query: 275 IHSRDDLDDIIQSSQTVSEDGDSL---CCNCK-----NVILLIDQHEMKCKDCVHLLKIK 326
H ++ D + S D D L C K + L D+ K +D + ++
Sbjct: 748 THQKE--FDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAED---VSSVE 802
Query: 327 KTFCLCKRLTELKDNHC---EQLRVKIRKLKNKASVLQK--------------------- 362
TF L + T E + ++ K Q+
Sbjct: 803 STFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTS 862
Query: 363 RLSEKEEIKSQLKHETLEL--------------EKELCSLRFAIQQEKKKRRNVE---EL 405
L KE+ KS E + + +KE+ + I++ +K + E E+
Sbjct: 863 ELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEM 922
Query: 406 HQKVREKLRITEEQYRIEADVT--KPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHE 463
V K + + + AD T I AL S E + +N Q+ T + E ++
Sbjct: 923 QNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQI--TAKMEQTKNK 980
Query: 464 NRLMQDEIARLRLEKDTIKNQNLE-KKYLKDFEIVKRKHEDLQKALKRNEETLAETIACY 522
++Q E++ + K ++NQ + ++ L + + E+ +RN + L E I
Sbjct: 981 FCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEE----KRRNVDILKEKIR-- 1034
Query: 523 SGQLAALTDENTTLRSKLEKQRESGQRL---ETEMQSYRCRLNAALCDHDQSHSSKRDQE 579
LR KLE +++ Q L + E++S LN SH+ + + +
Sbjct: 1035 ---------PEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQV------SHTHESEND 1079
Query: 580 LAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQ 639
L + + L + +L L+++ + + +V E + + L+EK +Q
Sbjct: 1080 LFHENCM---------LKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKN---AELQ 1127
Query: 640 SELKQKQSQMKDIEKMYK------SGYNTM--EKCIEKQER---FCQLKKQNMLLQQQLD 688
LK KQ + Y+ + NTM K EKQ++ +++ + L L
Sbjct: 1128 MTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKLKEKQDKEILETEIESHHPRLASALQ 1187
Query: 689 DARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYE 748
D +++ L + DA ++ + + ++ N + NE+ H E Q
Sbjct: 1188 DHDQSVTSRKNQELAFHSAGDAPLQGI--------MNVDVSNTIYNNEVLHQPLYEAQ-R 1238
Query: 749 KEKAEREVAVRQLQQKRDDVLNKGSATK-ALLDASSRHCTY--LENGMQDSRKKLDQMRS 805
K K+ + L DD+ ++ A D C E+ Q+ + +D+
Sbjct: 1239 KSKSPK----INLNYAGDDLRENALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTE 1294
Query: 806 QFQEIQDQL 814
Q + ++ +L
Sbjct: 1295 QQESLEQKL 1303
Score = 32.0 bits (71), Expect = 2.5
Identities = 28/170 (16%), Positives = 75/170 (44%), Gaps = 17/170 (10%)
Query: 697 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREV 756
+ K L + +++ + C + R L +++ + + ++ +K K C +KE +E +
Sbjct: 934 KNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKE 993
Query: 757 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 816
QL+ ++ + + + L N ++ R+ +D ++ + + ++QL
Sbjct: 994 IKSQLENQKAKWEQELCSVRLTL-----------NQEEEKRRNVDILKEKIRP-EEQLRK 1041
Query: 817 TIRCTKEMEGDAQKLEVENVMMRKIIK--KQDEQIERFEKILQHSSLMLQ 864
+ +++E Q L ++++ ++ + Q E L H + ML+
Sbjct: 1042 KLEVKQQLE---QTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLK 1088
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 280 bits (716), Expect = 4e-75
Identities = 165/268 (61%), Positives = 186/268 (69%), Gaps = 41/268 (15%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSSEKP GLKATSDEKDSVLNIARGKK GEKTR VSS K P LKATSD+E+SV ++A E
Sbjct: 671 TVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARE 730
Query: 67 TKDEQISGTVSSQK----------------------------------QPALKATSDKKD 92
KD + S TVSS+K +PALKATSD+KD
Sbjct: 731 NKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKD 790
Query: 93 SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPAL 152
SV I E KDG++S TVSSQKQPA KA K+DSV N+ATE KD QI GTVSSQ+QPAL
Sbjct: 791 SVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPAL 850
Query: 153 KATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTE 212
KAT D+KDSVSNI EIKDG++SGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGT
Sbjct: 851 KATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGT- 909
Query: 213 YPENLPTLKATIENKNSVLNTATKMKDV 240
++ IE+ + T K DV
Sbjct: 910 ------VIRQAIEHDECLCYTGIKPSDV 931
Score = 244 bits (622), Expect = 3e-64
Identities = 148/259 (57%), Positives = 171/259 (66%)
Query: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
VSS+K KATSD+KDSV NIA K G + VSS KQPA KATSD+++SV N+ATE
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
Query: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
K Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQPA KATS K DS
Sbjct: 324 KKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383
Query: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
NIATEIKDG GTVSSQ+QPALKAT DE+DSVSNIA EIKDGEKSGTVS QKQ A K
Sbjct: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
Query: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247
+K S+ NIAT I G KSGT + P L AT + + SVL+ A + KD + S
Sbjct: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503
Query: 248 QDLEMASEGEQKRLEEYEN 266
+ AS+ + + N
Sbjct: 504 SRKKPASKATSDEKDSFSN 522
Score = 244 bits (622), Expect = 3e-64
Identities = 150/304 (49%), Positives = 193/304 (63%), Gaps = 17/304 (5%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSSEKP GLKA+SDEKDSVLNIARGKK+GEKT+RVSS K+P+L+ATSD+++S N+ E
Sbjct: 569 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 628
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD +IS VSSQK PALK TSD++DSV I E KDG++S TVSS+K P KATS +KD
Sbjct: 629 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 688
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SV NIA KDG+ TVSSQ+ P LKAT DE+DSV +IARE KDGEKS TVS +K S
Sbjct: 689 SVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGL 748
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
K +K S+LNIA G K+ P LKAT + K+SVL A + KD + S
Sbjct: 749 KATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTV 808
Query: 247 EQDLE---------------MASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTV 291
+ MA+E + +++ ++Q Q + + D D + + T
Sbjct: 809 SSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQ--PALKATSDKKDSVSNIPTE 866
Query: 292 SEDG 295
+DG
Sbjct: 867 IKDG 870
Score = 229 bits (585), Expect = 6e-60
Identities = 137/237 (57%), Positives = 164/237 (69%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VS +K S K +K S+LNIA G K+ VSS KQPA KATSDK +S N+ATE
Sbjct: 331 TVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATE 390
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD GTVSSQKQPALKAT+D++DSVSNI TEIKDG++SGTVSSQKQPA KAT+ +KD
Sbjct: 391 IKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKD 450
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SVSNIATEIKDG+ GTVSSQ+ PAL AT DE+ SV +IARE KDGEKS TVS +K+ A
Sbjct: 451 SVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPAS 510
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
K +K S NI G S + PTLK T + ++SVL A + KD + S
Sbjct: 511 KATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKS 567
Score = 229 bits (583), Expect = 1e-59
Identities = 136/236 (57%), Positives = 164/236 (69%)
Query: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
VSS+KP LK TSDE+DSVL IAR K GEK+R VSS K P LKATSD+++SV N+A
Sbjct: 638 VSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGK 697
Query: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
KD + + TVSSQK P LKATSD++DSV +I E KDG++S TVSS+K KATS +KDS
Sbjct: 698 KDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDS 757
Query: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
V NIA K G+ VSS+++PALKAT DEKDSV IARE KDGEKS TVS QKQ A K
Sbjct: 758 VLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALK 817
Query: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
I K+ S+ N+AT SGT + P LKAT + K+SV N T++KD Q S
Sbjct: 818 AICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQS 873
Score = 228 bits (580), Expect = 2e-59
Identities = 144/292 (49%), Positives = 183/292 (62%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+K KATSD+ DS LNIA K G + VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 365 TVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 424
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD + SGTVSSQKQPALKAT+D+KDSVSNI TEIKDG++SGTVSSQK PA ATS ++
Sbjct: 425 IKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEG 484
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SV +IA E KDG+ TVSS+++PA KAT DEKDS SNI R KDGE S VS QK
Sbjct: 485 SVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 544
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
K ++ S+L IA G KS T E P LKA+ + K+SVLN A K + +
Sbjct: 545 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRV 604
Query: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 298
+ + E + + N + K+ SR + + S++ DS+
Sbjct: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 656
Score = 220 bits (560), Expect = 5e-57
Identities = 140/303 (46%), Positives = 183/303 (60%), Gaps = 13/303 (4%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS K KATSDEKDS NI RGKK GE +R+VSS K P LK TSD+E+SV +A E
Sbjct: 501 TVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARE 560
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD + S TVSS+K P LKA+SD+KDSV NI K G+++ VSS+K+P+ +ATS +KD
Sbjct: 561 NKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKD 620
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
S SNI E KDG+I VSSQ+ PALK T DE+DSV IARE KDGEKS TVS +K
Sbjct: 621 SFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 680
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS--- 243
K +K S+LNIA G K+ T + PTLKAT + ++SVL+ A + KD + S
Sbjct: 681 KATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTV 740
Query: 244 ----------TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSE 293
T AE+D + +K E+ + + K + + D D + +
Sbjct: 741 SSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKK 800
Query: 294 DGD 296
DG+
Sbjct: 801 DGE 803
Score = 212 bits (539), Expect = 1e-54
Identities = 137/277 (49%), Positives = 174/277 (62%), Gaps = 4/277 (1%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+KP L ATSDE+ SVL+IAR K GEK+R VSS K+PA KATSD+++S N+
Sbjct: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRG 526
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD +IS VSSQK P LK TSD++DSV I E KDG++S TVSS+K P KA+S +KD
Sbjct: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 586
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SV NIA K G+ VSS+++P+L+AT DEKDS SNI RE KDGE S VS QK A
Sbjct: 587 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKD-VQTSTP 245
K ++ S+L IA G KS T E P LKAT + K+SVLN A KD +T T
Sbjct: 647 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 706
Query: 246 AEQ---DLEMASEGEQKRLEEYENNQPQVKNQIHSRD 279
+ Q L+ S+ E L N+ K++ S +
Sbjct: 707 SSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSE 743
Score = 193 bits (491), Expect = 5e-49
Identities = 117/214 (54%), Positives = 136/214 (63%), Gaps = 2/214 (0%)
Query: 36 GEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVS 95
G+K VS + P T + + D S SS++ P T + D S
Sbjct: 191 GQKAN-VSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSS 249
Query: 96 NIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKAT 155
KD G VSSQKQPA KATS KDSVSNIATEIK+G I GTVSSQ+QPA KAT
Sbjct: 250 KAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKAT 309
Query: 156 GDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPE 215
DEKDSVSNIA EIK G++SGTVSPQKQSA+KVIFKKKVSLLNIATRI GG KSGT +
Sbjct: 310 SDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQ 369
Query: 216 NLPTLKATIENKNSVLNTATKMKD-VQTSTPAEQ 248
P KAT + +S LN AT++KD +Q T + Q
Sbjct: 370 KQPASKATSDKTDSALNIATEIKDGLQCGTVSSQ 403
Score = 192 bits (487), Expect = 1e-48
Identities = 122/267 (45%), Positives = 150/267 (56%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VS E+P T ++D + G + SS + P T + + A
Sbjct: 195 NVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMR 254
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD G VSSQKQPA KATSD KDSVSNI TEIK+G SGTVSSQKQPA KATS +KD
Sbjct: 255 RKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKD 314
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SVSNIATEIK GQ GTVS Q+Q A K +K S+ NIA I G KSGTVS QKQ A
Sbjct: 315 SVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS 374
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
K K S LNIAT I G + GT + P LKAT + ++SV N AT++KD + S
Sbjct: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
Query: 247 EQDLEMASEGEQKRLEEYENNQPQVKN 273
+ A + + N ++K+
Sbjct: 435 SSQKQPALKATTDEKDSVSNIATEIKD 461
Score = 61.6 bits (148), Expect = 3e-09
Identities = 82/306 (26%), Positives = 117/306 (38%), Gaps = 76/306 (24%)
Query: 42 VSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEI 101
VSS KQPALK TSDK++SV N ATE KDEQ SGTV + L + + D+V+ TE
Sbjct: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
Query: 102 KDGQQSGTVSSQKQPAWK----------------------------ATSVKKDSVSNIAT 133
+ +S +S P K A V KD + +
Sbjct: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
Query: 134 EIKDGQI--RGTVSSQRQPALKAT-GDEKDSVSNIAREIKDGEKSGTVSP---QKQSA-- 185
I + R T+S Q L A G +K N+ E ++ +K G P QK +
Sbjct: 140 NISEPYFTNRRTISQQSAENLDAACGIDKTENGNMF-EDQNVDKEGKALPATGQKANVSP 198
Query: 186 -QKVIFKKKV-SLLNIATRITGGWKSGTEYPEN--------------------------- 216
Q +F V +I+TR GG S T E+
Sbjct: 199 EQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDS 258
Query: 217 ----------LPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYEN 266
P KAT ++K+SV N AT++K+ S + A + + N
Sbjct: 259 PPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 318
Query: 267 NQPQVK 272
++K
Sbjct: 319 IATEIK 324
Score = 61.2 bits (147), Expect = 4e-09
Identities = 36/71 (50%), Positives = 42/71 (59%)
Query: 64 ATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV 123
A E S VSSQKQPALK TSDK DSVSN TEIKD Q+SGTV + +
Sbjct: 8 AASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLY 67
Query: 124 KKDSVSNIATE 134
+ D+V+ TE
Sbjct: 68 RPDAVAQPVTE 78
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 259 bits (661), Expect = 1e-68
Identities = 153/238 (64%), Positives = 169/238 (71%), Gaps = 34/238 (14%)
Query: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
VSS+KP LK TSDE+DSVL IAR K GEK+R VSS K P LKATSD+++SV N+A
Sbjct: 466 VSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGK 525
Query: 68 KDEQISGTVSSQKQPALKATS----------------------------------DKKDS 93
KD + + TVSS+K+PALKATS DK+DS
Sbjct: 526 KDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDS 585
Query: 94 VSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALK 153
V N+ TE KD Q SGTVSSQKQPA KATS KKDSVSNI TEIKDGQ GTVSSQ+QPA K
Sbjct: 586 VPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWK 645
Query: 154 ATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGT 211
AT +KDSVSNIA EIKDG+ GTVSPQKQSAQKVIFKKKVSLLNIATRITGG KSGT
Sbjct: 646 ATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 703
Score = 256 bits (655), Expect = 5e-68
Identities = 148/267 (55%), Positives = 185/267 (69%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSSEKP GLKA+SDEKDSVLNIARGKK+GEKT+RVSS K+P+L+ATSD+++S N+ E
Sbjct: 397 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 456
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD +IS VSSQK PALK TSD++DSV I E KDG++S TVSS+K P KATS +KD
Sbjct: 457 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 516
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SV NIA KDG+ TVSS+++PALKAT DEKDSV IARE KDGEKS TVS QKQ A
Sbjct: 517 SVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPAL 576
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
K I K+ S+ N+AT SGT + P LKAT + K+SV N T++KD Q S
Sbjct: 577 KAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 636
Query: 247 EQDLEMASEGEQKRLEEYENNQPQVKN 273
+ A + + + N ++K+
Sbjct: 637 SSQKQPAWKATSVKKDSVSNIATEIKD 663
Score = 256 bits (653), Expect = 8e-68
Identities = 146/205 (71%), Positives = 152/205 (74%), Gaps = 34/205 (16%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATS------------ 54
+VSSEKP GLKATSDEKDSVLNIARGKK GEKTR VSS K+PALKATS
Sbjct: 499 TVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIARE 558
Query: 55 ----------------------DKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKD 92
DKE+SVPNMATE KDEQISGTVSSQKQPALKATSDKKD
Sbjct: 559 KKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKD 618
Query: 93 SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPAL 152
SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVS Q+Q A
Sbjct: 619 SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQ 678
Query: 153 KATGDEKDSVSNIAREIKDGEKSGT 177
K +K S+ NIA I G KSGT
Sbjct: 679 KVIFKKKVSLLNIATRITGGGKSGT 703
Score = 227 bits (579), Expect = 3e-59
Identities = 144/301 (47%), Positives = 186/301 (61%), Gaps = 13/301 (4%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VS ++P GLKAT DEKDS+LNIARGKK+GEKTRRVSS K+PALKATSD+++S N+
Sbjct: 295 TVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRG 354
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD +IS VSSQK P LK TSD++DSV I E KDG++S TVSS+K P KA+S +KD
Sbjct: 355 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 414
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SV NIA K G+ VSS+++P+L+AT DEKDS SNI RE KDGE S VS QK A
Sbjct: 415 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 474
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQ----- 241
K ++ S+L IA G KS T E P LKAT + K+SVLN A KD +
Sbjct: 475 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 534
Query: 242 --------TSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSE 293
+T E+D + E+K E+ Q + + + D +D + + T +
Sbjct: 535 SSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKK 594
Query: 294 D 294
D
Sbjct: 595 D 595
Score = 221 bits (563), Expect = 2e-57
Identities = 133/266 (50%), Positives = 171/266 (64%)
Query: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
VSS+KP LK TSDE+DSVL IAR K GEK+R VSS K P LKA+SD+++SV N+A
Sbjct: 364 VSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGK 423
Query: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
K + + VSS+K+P+L+ATSD+KDS SNI E KDG+ S VSSQK PA K TS ++DS
Sbjct: 424 KYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDS 483
Query: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
V IA E KDG+ TVSS++ P LKAT DEKDSV NIAR KDGEK+ TVS +K+ A K
Sbjct: 484 VLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALK 543
Query: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247
+K S+L IA G KS T + P LKA + ++SV N AT+ KD Q S
Sbjct: 544 ATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVS 603
Query: 248 QDLEMASEGEQKRLEEYENNQPQVKN 273
+ A + + + N ++K+
Sbjct: 604 SQKQPALKATSDKKDSVSNIPTEIKD 629
Score = 220 bits (561), Expect = 4e-57
Identities = 140/303 (46%), Positives = 181/303 (59%), Gaps = 17/303 (5%)
Query: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
VSS K LKATSDEKDS NI RGKK GE +R+VSS K P LK TSD+E+SV +A E
Sbjct: 330 VSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAREN 389
Query: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
KD + S TVSS+K P LKA+SD+KDSV NI K G+++ VSS+K+P+ +ATS +KDS
Sbjct: 390 KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDS 449
Query: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
SNI E KDG+I VSSQ+ PALK T DE+DSV IARE KDGEKS TVS +K K
Sbjct: 450 FSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLK 509
Query: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247
+K S+LNIA G K+ T P LKAT + K+SVL A + KD + S
Sbjct: 510 ATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVS 569
Query: 248 QDLE---------------MASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVS 292
+ MA+E + +++ ++Q Q + + D D + + T
Sbjct: 570 SQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQ--PALKATSDKKDSVSNIPTEI 627
Query: 293 EDG 295
+DG
Sbjct: 628 KDG 630
Score = 217 bits (552), Expect = 4e-56
Identities = 134/261 (51%), Positives = 163/261 (62%)
Query: 6 FSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMAT 65
+++S +K KATSDEKDSV NIA K G+++ VS KQ A K K+ S+ N+AT
Sbjct: 90 YAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIAT 149
Query: 66 ETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKK 125
SGTVSSQKQPA K SDK DS N TEIKDG Q GTVSSQKQ A KAT+ ++
Sbjct: 150 RIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEE 209
Query: 126 DSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSA 185
SVSNIATEIKDG+ GTVSSQ++PALKAT DEKDS SNI RE KDGE S TVS QK A
Sbjct: 210 GSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPA 269
Query: 186 QKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTP 245
K K+ S+LNIA G KS T + P LKAT + K+S+LN A K+ + +
Sbjct: 270 LKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRR 329
Query: 246 AEQDLEMASEGEQKRLEEYEN 266
+ A + + + N
Sbjct: 330 VSSRKKPALKATSDEKDSFSN 350
Score = 210 bits (535), Expect = 4e-54
Identities = 129/237 (54%), Positives = 155/237 (65%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+K K SD+ DS LN A K G + VSS KQ ALKAT+D+E SV N+ATE
Sbjct: 159 TVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATE 218
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD + SGTVSSQK+PALKATSD+KDS SNI E KDG+ S TVSSQK PA KATSVK+D
Sbjct: 219 IKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKED 278
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SV NIA E KDG+ TVS + P LKAT DEKDS+ NIAR K+GEK+ VS +K+ A
Sbjct: 279 SVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPAL 338
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
K +K S NI G S + PTLK T + ++SVL A + KD + S
Sbjct: 339 KATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKS 395
Score = 210 bits (534), Expect = 5e-54
Identities = 130/237 (54%), Positives = 153/237 (64%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VS +K S K +K S+LNIA G K+ VSS KQPA K SDK +S N ATE
Sbjct: 125 TVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATE 184
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD GTVSSQKQ ALKAT+D++ SVSNI TEIKDG++SGTVSSQK+PA KATS +KD
Sbjct: 185 IKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKD 244
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
S SNI E KDG+I TVSSQ+ PALKAT ++DSV NIARE KDGEKS TVS +
Sbjct: 245 SFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGL 304
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
K +K SLLNIA G K+ P LKAT + K+S N KD + S
Sbjct: 305 KATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEIS 361
Score = 207 bits (526), Expect = 4e-53
Identities = 127/250 (50%), Positives = 157/250 (62%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+K LKATSDEKDS NI R KK GE +R VSS K PALKATS KE+SV N+A E
Sbjct: 227 TVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIARE 286
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD + S TVS + P LKAT D+KDS+ NI K+G+++ VSS+K+PA KATS +KD
Sbjct: 287 KKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKPALKATSDEKD 346
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
S SNI KDG+I VSSQ+ P LK T DE+DSV IARE KDGEKS TVS +K
Sbjct: 347 SFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 406
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
K +K S+LNIA G K+ P+L+AT + K+S N + KD + S
Sbjct: 407 KASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV 466
Query: 247 EQDLEMASEG 256
A +G
Sbjct: 467 SSQKPPALKG 476
Score = 204 bits (518), Expect = 4e-52
Identities = 133/292 (45%), Positives = 174/292 (59%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+K LKAT+DE+ SV NIA K GEK+ VSS K+PALKATSD+++S N+ E
Sbjct: 193 TVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITRE 252
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD +IS TVSSQK PALKATS K+DSV NI E KDG++S TVS + P KAT +KD
Sbjct: 253 KKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKD 312
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
S+ NIA K+G+ VSS+++PALKAT DEKDS SNI R KDGE S VS QK
Sbjct: 313 SLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 372
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
K ++ S+L IA G KS T E P LKA+ + K+SVLN A K + +
Sbjct: 373 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRV 432
Query: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 298
+ + E + + N + K+ SR + + S++ DS+
Sbjct: 433 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 484
Score = 165 bits (417), Expect = 2e-40
Identities = 162/535 (30%), Positives = 240/535 (44%), Gaps = 48/535 (8%)
Query: 76 VSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEI 135
+S QKQPA KATSD+KDSVSNI TEIK+GQQSGTVS QKQ A K KK S+ NIAT I
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 136 KDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVS 195
G GTVSSQ+QPA K D+ DS N A EIKDG + GTVS QKQ A K ++ S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 196 LLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASE 255
+ NIAT I G KSGT + P LKAT + K+S N + KD + S A +
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 256 GEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMK 315
+ + N + K+ SR D + ++ DSL L I + +
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSL--------LNIARGKKN 323
Query: 316 CKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVK-----IRKLKNKASVLQKRLSEKEEI 370
+ + KK K ++ KD+ R K RK+ ++ K S++E+
Sbjct: 324 GEKTRRVSSRKKP--ALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDS 381
Query: 371 KSQLKHETLELEK------ELCSLRFAIQQEKKKRRNVE------ELHQKVREKLRITEE 418
+ E + EK E A EK N+ E ++V + + + E
Sbjct: 382 VLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLE 441
Query: 419 QYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEK 478
E D I K E+ K + T ++ED + + R K
Sbjct: 442 ATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV---------LGIARENK 492
Query: 479 DTIKNQNLEKKY---LKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTT 535
D K++ + + LK K ++ + K E+T T++ T +
Sbjct: 493 DGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKT--RTVSSRKKPALKATSDEKD 550
Query: 536 LRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQS----HSSKRDQELAFQGTV 586
+ ++++ G++ T + S + A+CD + S + K+D++++ GTV
Sbjct: 551 SVLYIAREKKDGEKSRT-VSSQKQPALKAICDKEDSVPNMATEKKDEQIS--GTV 602
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 255 bits (651), Expect = 1e-67
Identities = 158/298 (53%), Positives = 191/298 (64%)
Query: 1 MNPFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSV 60
M PF FSVSS+K KATSD+KDSV NIA K G + VSS KQPA KATSD+++SV
Sbjct: 1 MYPFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSV 60
Query: 61 PNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKA 120
N+ATE K+ Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQPA KA
Sbjct: 61 SNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKA 120
Query: 121 TSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSP 180
TS K DS NIATEIKDG GTVSSQ+QPALKAT DE+DSVSNIA EIKDGEKSGTVS
Sbjct: 121 TSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSS 180
Query: 181 QKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDV 240
QKQ A K ++ S+LNIAT I G KS T + P LKAT + ++SV AT++KD
Sbjct: 181 QKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDG 240
Query: 241 QTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 298
+ S + A + + + N + K+ SR + + S++ DS+
Sbjct: 241 EKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSV 298
Score = 241 bits (616), Expect = 2e-63
Identities = 139/237 (58%), Positives = 171/237 (72%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+K KATSD+ DS LNIA K G + VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 109 TVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 168
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD + SGTVSSQKQPALKAT+D++DSV NI TEIKDG++S TVSSQKQPA KAT+ ++D
Sbjct: 169 IKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEED 228
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SVS IATEIKDG+ GTVSS+++PALKAT DEKDS SNI RE KDGE S TV+ +K +
Sbjct: 229 SVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGL 288
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
K ++ S+LNIA G K+ P LKAT + K+S N + KD +TS
Sbjct: 289 KATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETS 345
Score = 235 bits (599), Expect = 2e-61
Identities = 155/330 (46%), Positives = 192/330 (58%), Gaps = 34/330 (10%)
Query: 3 PFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGE------------------------- 37
P +VSS+K KATSDEKDSV NIA K G+
Sbjct: 37 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLN 96
Query: 38 ---------KTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATS 88
K+ VSS KQPA KATSDK +S N+ATE KD GTVSSQKQPALKAT+
Sbjct: 97 IATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 156
Query: 89 DKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQR 148
D++DSVSNI TEIKDG++SGTVSSQKQPA KAT+ ++DSV NIATEIKDG+ TVSSQ+
Sbjct: 157 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQK 216
Query: 149 QPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWK 208
QPALKAT DE+DSVS IA EIKDGEKSGTVS +K+ A K +K S NI G
Sbjct: 217 QPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEI 276
Query: 209 SGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQ 268
S T E LKAT + ++SVLN A +D + + + A + + + N
Sbjct: 277 SRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNIT 336
Query: 269 PQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 298
+ K+ SR + + S++ DS+
Sbjct: 337 REKKDGETSRTVSSQKPPALKATSDEEDSV 366
Score = 232 bits (592), Expect = 1e-60
Identities = 135/237 (56%), Positives = 170/237 (71%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+K LKAT+DE+DSV NIA K GEK+ VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 143 TVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATE 202
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD + S TVSSQKQPALKAT+D++DSVS I TEIKDG++SGTVSS+K+PA KATS +KD
Sbjct: 203 IKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKD 262
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
S SNI E KDG+I TV+S++ LKAT DE+DSV NIAR +DGEK+ VS +K+ A
Sbjct: 263 SFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPAL 322
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 243
K +K S NI G S T + P LKAT + ++SVL+ A + KD + S
Sbjct: 323 KATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKS 379
Score = 213 bits (542), Expect = 6e-55
Identities = 126/215 (58%), Positives = 153/215 (71%)
Query: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
+VSS+K LKAT+DE+DSVLNIA K GEK+ VSS KQPALKAT+D+E+SV +ATE
Sbjct: 177 TVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATE 236
Query: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
KD + SGTVSS+K+PALKATSD+KDS SNI E KDG+ S TV+S+K KATS ++D
Sbjct: 237 IKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEED 296
Query: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
SV NIA +DG+ VSS+++PALKAT DEKDS SNI RE KDGE S TVS QK A
Sbjct: 297 SVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPAL 356
Query: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLK 221
K ++ S+L+IA G KS T E P LK
Sbjct: 357 KATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 251 bits (641), Expect = 2e-66
Identities = 190/574 (33%), Positives = 295/574 (51%), Gaps = 95/574 (16%)
Query: 202 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 261
RI G G P P+LK + E ++ + A + K+VQT AEQ L +ASE EQ+R
Sbjct: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
Query: 262 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 321
E E QPQ +I+ + T +
Sbjct: 376 ERSEKKQPQ-------------VIEGNNTYKSE--------------------------- 395
Query: 322 LLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---T 378
KI +L +N C + S RL+++ +I +
Sbjct: 396 --KI-----------QLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
Query: 379 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 438
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
Query: 439 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 495
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
Query: 496 IVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ 555
I K + L+K +K NEE + +T Y +L L ENT L S+L K++ES ++LE E++
Sbjct: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
Query: 556 SYRCRLNAALCDHDQSHSSKRDQELAFQGTVD-----KCCHLQENLNSHVLILSLQLSKA 610
SY+ RL AA+ H ++ ++R+ +LA + T D K + L+ QLSK
Sbjct: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
Query: 611 ESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 669
+ KF L+ + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
Query: 670 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 726
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
Query: 727 EEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQ 760
EE NK L+NE H KE QYE++KAE V++++
Sbjct: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 251 bits (641), Expect = 2e-66
Identities = 190/574 (33%), Positives = 295/574 (51%), Gaps = 95/574 (16%)
Query: 202 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 261
RI G G P P+LK + E ++ + A + K+VQT AEQ L +ASE EQ+R
Sbjct: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
Query: 262 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 321
E E QPQ +I+ + T +
Sbjct: 376 ERSEKKQPQ-------------VIEGNNTYKSE--------------------------- 395
Query: 322 LLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---T 378
KI +L +N C + S RL+++ +I +
Sbjct: 396 --KI-----------QLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
Query: 379 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 438
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
Query: 439 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 495
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
Query: 496 IVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ 555
I K + L+K +K NEE + +T Y +L L ENT L S+L K++ES ++LE E++
Sbjct: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
Query: 556 SYRCRLNAALCDHDQSHSSKRDQELAFQGTVD-----KCCHLQENLNSHVLILSLQLSKA 610
SY+ RL AA+ H ++ ++R+ +LA + T D K + L+ QLSK
Sbjct: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
Query: 611 ESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 669
+ KF L+ + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
Query: 670 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 726
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
Query: 727 EEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQ 760
EE NK L+NE H KE QYE++KAE V++++
Sbjct: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 223 bits (569), Expect = 5e-58
Identities = 148/435 (34%), Positives = 247/435 (56%), Gaps = 29/435 (6%)
Query: 341 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---TLELEKELCSLRFAIQQEKK 397
N E++++ + +S RL+++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 398 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ-VSETDE 456
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N+ +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEE 506
Query: 457 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEET 514
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K NEE
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 515 LAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSS 574
+ ET Y +L L ENT L ++L K++ES +RLE +++SY+ RL AA+ H +S +
Sbjct: 567 ITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 575 KRDQELAFQGTVDKCCHLQ-----ENLNSHVLILSLQLSKAESKFRVLETELHYTGEALK 629
+R+ +LA + T D ++ + L+ QLS+ + KF L+ + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 630 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 685
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 686 QLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKEC 745
QLDD K D++E + NIQ E K L+LEE +K L+NE H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 746 QYEKEKAEREVAVRQ 760
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 223 bits (569), Expect = 5e-58
Identities = 148/435 (34%), Positives = 247/435 (56%), Gaps = 29/435 (6%)
Query: 341 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---TLELEKELCSLRFAIQQEKK 397
N E++++ + +S RL+++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 398 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ-VSETDE 456
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N+ +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEE 506
Query: 457 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEET 514
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K NEE
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 515 LAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSS 574
+ ET Y +L L ENT L ++L K++ES +RLE +++SY+ RL AA+ H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 575 KRDQELAFQGTVDKCCHLQ-----ENLNSHVLILSLQLSKAESKFRVLETELHYTGEALK 629
+R+ +LA + T D ++ + L+ QLS+ + KF L+ + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 630 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 685
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 686 QLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKEC 745
QLDD K D++E + NIQ E K L+LEE +K L+NE H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 746 QYEKEKAEREVAVRQ 760
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 223 bits (569), Expect = 5e-58
Identities = 148/435 (34%), Positives = 247/435 (56%), Gaps = 29/435 (6%)
Query: 341 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---TLELEKELCSLRFAIQQEKK 397
N E++++ + +S RL+++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 398 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN-QVSETDE 456
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEE 506
Query: 457 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEET 514
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K NEE
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 515 LAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSS 574
+ ET Y +L L ENT L ++L K++ES +RLE +++SY+ RL AA+ H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 575 KRDQELAFQGTVDKCCHLQ-----ENLNSHVLILSLQLSKAESKFRVLETELHYTGEALK 629
+R+ +LA + T D ++ + + L+ QLS+ + KF L+ + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 630 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 685
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 686 QLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKEC 745
QLDD K D++E + NIQ E K L+LEE +K L+NE H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 746 QYEKEKAEREVAVRQ 760
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 221 bits (562), Expect = 3e-57
Identities = 147/435 (33%), Positives = 244/435 (56%), Gaps = 29/435 (6%)
Query: 341 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---TLELEKELCSLRFAIQQEKK 397
N E++++ + +S RL+++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 398 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN-QVSETDE 456
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEE 506
Query: 457 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEET 514
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K NEE
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 515 LAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSS 574
+ ET Y +L L ENT L ++L K++ES +RLE +++SY+ RL AA+ H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 575 KRDQELAFQGTVDKCCHLQ-----ENLNSHVLILSLQLSKAESKFRVLETELHYTGEALK 629
+R+ +LA + T D ++ + L+ QLS+ + KF L+ + T ++L+
Sbjct: 627 ERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 630 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 685
+K+L E VQ+ L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 686 QLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKEC 745
QLDD K D++E + NIQ E K +LEE +K L+NE H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDFVLEEKSKKLMNECDHLKESLF 797
Query: 746 QYEKEKAEREVAVRQ 760
QYE+EK E V++++
Sbjct: 798 QYEREKTEVVVSIKE 812
>gi|169217530 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 121
Score = 216 bits (551), Expect = 6e-56
Identities = 110/116 (94%), Positives = 114/116 (98%)
Query: 753 EREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD 812
E++VAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD
Sbjct: 6 EKKVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD 65
Query: 813 QLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVFES 868
QLTATIRCTKEMEGD QKLEVE+VMMRKIIKKQD+QIER EKILQHSSLMLQVFES
Sbjct: 66 QLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 121
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 211 bits (537), Expect = 2e-54
Identities = 165/524 (31%), Positives = 284/524 (54%), Gaps = 55/524 (10%)
Query: 358 SVLQKRLSEKEE-IKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRIT 416
S+ Q+ L K + +K+ L+++ E A++ E K+R K R+KL+
Sbjct: 346 SIQQQILEHKNKMLKNHLRNDNQETA--------AMKPENLKKR-------KKRKKLKKR 390
Query: 417 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLMQDEIARLR 475
+E + E + +K A + + L+ N Q S++ +K+D + N +++ +IA L+
Sbjct: 391 KEGAKAEHN----LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLK 446
Query: 476 LEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDEN 533
E IKN +L EKKY+++ + + + + +K+++ NEE + + +A YS QL L EN
Sbjct: 447 EELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAEN 506
Query: 534 TTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQ 593
L SKLEK++ + +RLE E++S L A+ ++++ ++D EL D H
Sbjct: 507 ARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEI-LERKDLELVLWRADDVSRH-- 563
Query: 594 ENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQ 646
E + S++ +L+ Q+ KA KF L+ +L T +AL+EK L E VQ +LKQ Q
Sbjct: 564 ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQ 623
Query: 647 SQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 702
++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN+E ++
Sbjct: 624 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVI 682
Query: 703 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQ 762
NI C +EN + + LLEE NK L+NE + KEK QYEKEKAEREV VR+ Q
Sbjct: 683 NIHRDC---LENGKED------LLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQ 733
Query: 763 QKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTK 822
++ D L K S +++ L+ +S HC + S+KKL Q+ Q +E ++
Sbjct: 734 EELVDHLKKFSMSESPLEGTS-HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELIS 792
Query: 823 EMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 866
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 793 LLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 829
Score = 63.9 bits (154), Expect = 6e-10
Identities = 131/639 (20%), Positives = 262/639 (41%), Gaps = 95/639 (14%)
Query: 236 KMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 295
K+K + AE +L++ASE +Q+RLE EN QP Q SQ+ +
Sbjct: 386 KLKKRKEGAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKK 429
Query: 296 DSLCCN--CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKL 353
D + N K I ++ + K+ L K KK K +TE+ N + +R+ +
Sbjct: 430 DEMFGNFMLKRDIAMLKEELYAIKN-DSLRKEKKYIQEIKSITEINANFEKSVRLNEEMI 488
Query: 354 KNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKL 413
K + ++L++ LK E L +L ++EK + +E + + L
Sbjct: 489 TKKVAQYSQQLND-------LKAENARLNSKL-------EKEKHNKERLEAEVESLHSNL 534
Query: 414 RITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENRLMQDE 470
+Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R+ +
Sbjct: 535 ATAINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNT 593
Query: 471 I-ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAA 528
+ +LR +D ++ + L + ++ D + + + +++++ E +++I +
Sbjct: 594 LKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEER 653
Query: 529 LTD---ENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 585
+ EN L +LE R+ G E + +R L + + +R++EL
Sbjct: 654 IRQRELENLLLERQLEDARKEGDNKEIVINIHR----DCLENGKEDLLEERNKEL----- 704
Query: 586 VDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQK 645
+++ +L+E L L + KAE + V E + E L + F +S L+
Sbjct: 705 MNEYNYLKEKL------LQYEKEKAEREVIVREFQ-----EELVDHLKKFSMSESPLEGT 753
Query: 646 QSQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 702
++++ + S + I EK E F ++ + LL D R K N+E
Sbjct: 754 SHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--NRE---- 807
Query: 703 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQ 762
L+ E ++ LE ML ++ + ++ ++L+
Sbjct: 808 ------------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLK 855
Query: 763 QKRDDVLNKGSATKA-----LLDASSRHCTYLENG-MQDSRKKLDQMRSQFQEIQDQLTA 816
QK DD++ + A + D H L G +Q+ +KL++ + +E
Sbjct: 856 QKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE------K 909
Query: 817 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKI 855
+ ME D +L ++ ++ + IE+ E+I
Sbjct: 910 VLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 948
Score = 35.0 bits (79), Expect = 0.30
Identities = 39/202 (19%), Positives = 89/202 (44%), Gaps = 26/202 (12%)
Query: 278 RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTE 337
+ DD++ + VS S C N L +E+ ++ + + K+++ C++L +
Sbjct: 855 KQKFDDLMAEKEAVS----SKCVN------LAKDNEVLHQELLSMGKVQEK---CEKLEK 901
Query: 338 LKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKK 397
K + L K+ LK L + +E KS+L ++ ++L + Q E +
Sbjct: 902 DK----KMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYE 957
Query: 398 KRR---NVEELHQKVREKLRITEEQYRIEA------DVTKPIKPALKSAEVELKTGGNNS 448
K+ N + +++L + + + + DVT ++ ++ V LK + S
Sbjct: 958 KQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMS 1017
Query: 449 NQVSETDEKEDLLHENRLMQDE 470
+++++D+K ++ M+ E
Sbjct: 1018 EKITKSDKKIAVISTKLFMEKE 1039
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 211 bits (537), Expect = 2e-54
Identities = 165/524 (31%), Positives = 284/524 (54%), Gaps = 55/524 (10%)
Query: 358 SVLQKRLSEKEE-IKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRIT 416
S+ Q+ L K + +K+ L+++ E A++ E K+R K R+KL+
Sbjct: 375 SIQQQILEHKNKMLKNHLRNDNQETA--------AMKPENLKKR-------KKRKKLKKR 419
Query: 417 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLMQDEIARLR 475
+E + E + +K A + + L+ N Q S++ +K+D + N +++ +IA L+
Sbjct: 420 KEGAKAEHN----LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLK 475
Query: 476 LEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDEN 533
E IKN +L EKKY+++ + + + + +K+++ NEE + + +A YS QL L EN
Sbjct: 476 EELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAEN 535
Query: 534 TTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQ 593
L SKLEK++ + +RLE E++S L A+ ++++ ++D EL D H
Sbjct: 536 ARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEI-LERKDLELVLWRADDVSRH-- 592
Query: 594 ENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQ 646
E + S++ +L+ Q+ KA KF L+ +L T +AL+EK L E VQ +LKQ Q
Sbjct: 593 ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQ 652
Query: 647 SQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 702
++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN+E ++
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVI 711
Query: 703 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQ 762
NI C +EN + + LLEE NK L+NE + KEK QYEKEKAEREV VR+ Q
Sbjct: 712 NIHRDC---LENGKED------LLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQ 762
Query: 763 QKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTK 822
++ D L K S +++ L+ +S HC + S+KKL Q+ Q +E ++
Sbjct: 763 EELVDHLKKFSMSESPLEGTS-HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELIS 821
Query: 823 EMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 866
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 822 LLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 858
Score = 63.9 bits (154), Expect = 6e-10
Identities = 131/639 (20%), Positives = 262/639 (41%), Gaps = 95/639 (14%)
Query: 236 KMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 295
K+K + AE +L++ASE +Q+RLE EN QP Q SQ+ +
Sbjct: 415 KLKKRKEGAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKK 458
Query: 296 DSLCCN--CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKL 353
D + N K I ++ + K+ L K KK K +TE+ N + +R+ +
Sbjct: 459 DEMFGNFMLKRDIAMLKEELYAIKN-DSLRKEKKYIQEIKSITEINANFEKSVRLNEEMI 517
Query: 354 KNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKL 413
K + ++L++ LK E L +L ++EK + +E + + L
Sbjct: 518 TKKVAQYSQQLND-------LKAENARLNSKL-------EKEKHNKERLEAEVESLHSNL 563
Query: 414 RITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENRLMQDE 470
+Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R+ +
Sbjct: 564 ATAINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNT 622
Query: 471 I-ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAA 528
+ +LR +D ++ + L + ++ D + + + +++++ E +++I +
Sbjct: 623 LKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEER 682
Query: 529 LTD---ENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 585
+ EN L +LE R+ G E + +R L + + +R++EL
Sbjct: 683 IRQRELENLLLERQLEDARKEGDNKEIVINIHR----DCLENGKEDLLEERNKEL----- 733
Query: 586 VDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQK 645
+++ +L+E L L + KAE + V E + E L + F +S L+
Sbjct: 734 MNEYNYLKEKL------LQYEKEKAEREVIVREFQ-----EELVDHLKKFSMSESPLEGT 782
Query: 646 QSQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 702
++++ + S + I EK E F ++ + LL D R K N+E
Sbjct: 783 SHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--NRE---- 836
Query: 703 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQ 762
L+ E ++ LE ML ++ + ++ ++L+
Sbjct: 837 ------------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLK 884
Query: 763 QKRDDVLNKGSATKA-----LLDASSRHCTYLENG-MQDSRKKLDQMRSQFQEIQDQLTA 816
QK DD++ + A + D H L G +Q+ +KL++ + +E
Sbjct: 885 QKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE------K 938
Query: 817 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKI 855
+ ME D +L ++ ++ + IE+ E+I
Sbjct: 939 VLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 977
Score = 35.0 bits (79), Expect = 0.30
Identities = 39/202 (19%), Positives = 89/202 (44%), Gaps = 26/202 (12%)
Query: 278 RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTE 337
+ DD++ + VS S C N L +E+ ++ + + K+++ C++L +
Sbjct: 884 KQKFDDLMAEKEAVS----SKCVN------LAKDNEVLHQELLSMGKVQEK---CEKLEK 930
Query: 338 LKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKK 397
K + L K+ LK L + +E KS+L ++ ++L + Q E +
Sbjct: 931 DK----KMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYE 986
Query: 398 KRR---NVEELHQKVREKLRITEEQYRIEA------DVTKPIKPALKSAEVELKTGGNNS 448
K+ N + +++L + + + + DVT ++ ++ V LK + S
Sbjct: 987 KQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMS 1046
Query: 449 NQVSETDEKEDLLHENRLMQDE 470
+++++D+K ++ M+ E
Sbjct: 1047 EKITKSDKKIAVISTKLFMEKE 1068
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 211 bits (537), Expect = 2e-54
Identities = 165/524 (31%), Positives = 284/524 (54%), Gaps = 55/524 (10%)
Query: 358 SVLQKRLSEKEE-IKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRIT 416
S+ Q+ L K + +K+ L+++ E A++ E K+R K R+KL+
Sbjct: 375 SIQQQILEHKNKMLKNHLRNDNQETA--------AMKPENLKKR-------KKRKKLKKR 419
Query: 417 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLMQDEIARLR 475
+E + E + +K A + + L+ N Q S++ +K+D + N +++ +IA L+
Sbjct: 420 KEGAKAEHN----LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLK 475
Query: 476 LEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDEN 533
E IKN +L EKKY+++ + + + + +K+++ NEE + + +A YS QL L EN
Sbjct: 476 EELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAEN 535
Query: 534 TTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQ 593
L SKLEK++ + +RLE E++S L A+ ++++ ++D EL D H
Sbjct: 536 ARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEI-LERKDLELVLWRADDVSRH-- 592
Query: 594 ENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQ 646
E + S++ +L+ Q+ KA KF L+ +L T +AL+EK L E VQ +LKQ Q
Sbjct: 593 ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQ 652
Query: 647 SQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 702
++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN+E ++
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVI 711
Query: 703 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQ 762
NI C +EN + + LLEE NK L+NE + KEK QYEKEKAEREV VR+ Q
Sbjct: 712 NIHRDC---LENGKED------LLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQ 762
Query: 763 QKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTK 822
++ D L K S +++ L+ +S HC + S+KKL Q+ Q +E ++
Sbjct: 763 EELVDHLKKFSMSESPLEGTS-HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELIS 821
Query: 823 EMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 866
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 822 LLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 858
Score = 63.9 bits (154), Expect = 6e-10
Identities = 131/639 (20%), Positives = 262/639 (41%), Gaps = 95/639 (14%)
Query: 236 KMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 295
K+K + AE +L++ASE +Q+RLE EN QP Q SQ+ +
Sbjct: 415 KLKKRKEGAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKK 458
Query: 296 DSLCCN--CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKL 353
D + N K I ++ + K+ L K KK K +TE+ N + +R+ +
Sbjct: 459 DEMFGNFMLKRDIAMLKEELYAIKN-DSLRKEKKYIQEIKSITEINANFEKSVRLNEEMI 517
Query: 354 KNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKL 413
K + ++L++ LK E L +L ++EK + +E + + L
Sbjct: 518 TKKVAQYSQQLND-------LKAENARLNSKL-------EKEKHNKERLEAEVESLHSNL 563
Query: 414 RITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENRLMQDE 470
+Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R+ +
Sbjct: 564 ATAINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNT 622
Query: 471 I-ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAA 528
+ +LR +D ++ + L + ++ D + + + +++++ E +++I +
Sbjct: 623 LKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEER 682
Query: 529 LTD---ENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 585
+ EN L +LE R+ G E + +R L + + +R++EL
Sbjct: 683 IRQRELENLLLERQLEDARKEGDNKEIVINIHR----DCLENGKEDLLEERNKEL----- 733
Query: 586 VDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQK 645
+++ +L+E L L + KAE + V E + E L + F +S L+
Sbjct: 734 MNEYNYLKEKL------LQYEKEKAEREVIVREFQ-----EELVDHLKKFSMSESPLEGT 782
Query: 646 QSQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 702
++++ + S + I EK E F ++ + LL D R K N+E
Sbjct: 783 SHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--NRE---- 836
Query: 703 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQ 762
L+ E ++ LE ML ++ + ++ ++L+
Sbjct: 837 ------------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLK 884
Query: 763 QKRDDVLNKGSATKA-----LLDASSRHCTYLENG-MQDSRKKLDQMRSQFQEIQDQLTA 816
QK DD++ + A + D H L G +Q+ +KL++ + +E
Sbjct: 885 QKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE------K 938
Query: 817 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKI 855
+ ME D +L ++ ++ + IE+ E+I
Sbjct: 939 VLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 977
Score = 35.0 bits (79), Expect = 0.30
Identities = 39/202 (19%), Positives = 89/202 (44%), Gaps = 26/202 (12%)
Query: 278 RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTE 337
+ DD++ + VS S C N L +E+ ++ + + K+++ C++L +
Sbjct: 884 KQKFDDLMAEKEAVS----SKCVN------LAKDNEVLHQELLSMGKVQEK---CEKLEK 930
Query: 338 LKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKK 397
K + L K+ LK L + +E KS+L ++ ++L + Q E +
Sbjct: 931 DK----KMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYE 986
Query: 398 KRR---NVEELHQKVREKLRITEEQYRIEA------DVTKPIKPALKSAEVELKTGGNNS 448
K+ N + +++L + + + + DVT ++ ++ V LK + S
Sbjct: 987 KQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMS 1046
Query: 449 NQVSETDEKEDLLHENRLMQDE 470
+++++D+K ++ M+ E
Sbjct: 1047 EKITKSDKKIAVISTKLFMEKE 1068
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 201 bits (510), Expect = 3e-51
Identities = 159/530 (30%), Positives = 278/530 (52%), Gaps = 37/530 (6%)
Query: 355 NKASVLQKRLSEKEEIKSQ----LKHETLELEKELCSLRFAIQQEKKK--RRNVEELHQK 408
N +S++ L + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 318 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 377
Query: 409 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 467
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 378 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 437
Query: 468 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQ 525
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ NE+ + +T+A YS Q
Sbjct: 438 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 497
Query: 526 LAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 585
L L EN L S+LEK++ + +RLE E++S L A+ ++++ ++D EL
Sbjct: 498 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 556
Query: 586 VDKCCHLQENLNSHVL-----ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQS 640
D H + N L +L+ Q+ KA KF L+ +L T +AL+EK L VQ
Sbjct: 557 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 616
Query: 641 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 696
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 617 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 676
Query: 697 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREV 756
+E ++NI C +EN + + LLEE NK L+ E + KEK Q EKEKAEREV
Sbjct: 677 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 726
Query: 757 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 816
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 727 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785
Query: 817 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 866
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 786 LFELISLLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 828
Score = 65.5 bits (158), Expect = 2e-10
Identities = 154/724 (21%), Positives = 276/724 (38%), Gaps = 181/724 (25%)
Query: 225 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 284
+N+ + +K + AE +L++ASE +Q+RL+ EN QP
Sbjct: 374 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP--------------- 418
Query: 285 IQSSQTVSEDGDSLCCNC---KNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDN 341
Q SQ+ + D++ N K++ +L + E+ L K KK K +TE+ N
Sbjct: 419 -QDSQSYGKKKDAMYGNFMLKKDIAML--KEELYAIKNDSLRKEKKYIQEIKSITEINAN 475
Query: 342 HCEQLRVKIRKLKNKASVLQKRL----SEKEEIKSQL---KHETLELEKELCSLRFA--- 391
+ +R+ + + + ++L +E + S+L KH LE E+ SL +
Sbjct: 476 FEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLAT 535
Query: 392 -----------------------IQQEKKKRRNVEELHQK-----------------VRE 411
+ + +K N+ +L K ++
Sbjct: 536 AINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKG 595
Query: 412 KLRITEEQYRIEADVTKPIKPALKSAEVELK----TGGNNSNQVSETDEKEDLLHENRLM 467
KLR T + R + ++ L+ A+ +K N + S++ K++ L E R+
Sbjct: 596 KLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSL-EERIR 654
Query: 468 QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLA 527
Q E+ L LE+ +K + EIV H D L+ +E L E +
Sbjct: 655 QQELENLLLERQL----EDARKEGDNKEIVINIHRD---CLENGKEDLLEE------RNK 701
Query: 528 ALTDENTTLRSKL---EKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQG 584
L E L+ KL EK++ + + E Q L DH ++ S E +G
Sbjct: 702 ELMKEYNYLKEKLLQCEKEKAEREVIVREFQE-------ELVDHLKTFSI---SESPLEG 751
Query: 585 TVDKCCHLQENLNSHVLILSLQLSKAES-----KFRVLETELHYTGEALKEKALVFEH-- 637
T +L E S + +++ E K L + L+YT + +++K E
Sbjct: 752 TSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEA 811
Query: 638 -----------------------VQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFC 674
+L Q +M + K K +N + E C
Sbjct: 812 TGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSEC 871
Query: 675 -QLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKML 733
L K N +L Q+L R N+Q +C K LE+D KML
Sbjct: 872 VNLAKDNEVLHQELLSMR----------------------NVQEKCEK----LEKDKKML 905
Query: 734 VNELTHSK---EKEC-------QYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASS 783
E+ + K EK+ +Y+ E ER AV+++++ + L K + + L+ +
Sbjct: 906 EEEVLNLKTHMEKDMVELGKLQEYKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLN 963
Query: 784 RHCT----YLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMR 839
+ T E ++D K +M++ ++E+ +L + E A ++ N M +
Sbjct: 964 KDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL------EEFKEAFAGAVKANNSMSK 1017
Query: 840 KIIK 843
K++K
Sbjct: 1018 KLMK 1021
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 201 bits (510), Expect = 3e-51
Identities = 159/530 (30%), Positives = 278/530 (52%), Gaps = 37/530 (6%)
Query: 355 NKASVLQKRLSEKEEIKSQ----LKHETLELEKELCSLRFAIQQEKKK--RRNVEELHQK 408
N +S++ L + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 211 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 270
Query: 409 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 467
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 271 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 330
Query: 468 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQ 525
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ NE+ + +T+A YS Q
Sbjct: 331 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 390
Query: 526 LAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 585
L L EN L S+LEK++ + +RLE E++S L A+ ++++ ++D EL
Sbjct: 391 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 449
Query: 586 VDKCCHLQENLNSHVL-----ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQS 640
D H + N L +L+ Q+ KA KF L+ +L T +AL+EK L VQ
Sbjct: 450 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 509
Query: 641 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 696
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 510 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 569
Query: 697 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREV 756
+E ++NI C +EN + + LLEE NK L+ E + KEK Q EKEKAEREV
Sbjct: 570 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 619
Query: 757 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 816
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 620 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 678
Query: 817 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 866
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 679 LFELISLLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 721
Score = 65.5 bits (158), Expect = 2e-10
Identities = 154/724 (21%), Positives = 276/724 (38%), Gaps = 181/724 (25%)
Query: 225 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 284
+N+ + +K + AE +L++ASE +Q+RL+ EN QP
Sbjct: 267 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP--------------- 311
Query: 285 IQSSQTVSEDGDSLCCNC---KNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDN 341
Q SQ+ + D++ N K++ +L + E+ L K KK K +TE+ N
Sbjct: 312 -QDSQSYGKKKDAMYGNFMLKKDIAML--KEELYAIKNDSLRKEKKYIQEIKSITEINAN 368
Query: 342 HCEQLRVKIRKLKNKASVLQKRL----SEKEEIKSQL---KHETLELEKELCSLRFA--- 391
+ +R+ + + + ++L +E + S+L KH LE E+ SL +
Sbjct: 369 FEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLAT 428
Query: 392 -----------------------IQQEKKKRRNVEELHQK-----------------VRE 411
+ + +K N+ +L K ++
Sbjct: 429 AINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKG 488
Query: 412 KLRITEEQYRIEADVTKPIKPALKSAEVELK----TGGNNSNQVSETDEKEDLLHENRLM 467
KLR T + R + ++ L+ A+ +K N + S++ K++ L E R+
Sbjct: 489 KLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSL-EERIR 547
Query: 468 QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLA 527
Q E+ L LE+ +K + EIV H D L+ +E L E +
Sbjct: 548 QQELENLLLERQL----EDARKEGDNKEIVINIHRD---CLENGKEDLLEE------RNK 594
Query: 528 ALTDENTTLRSKL---EKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQG 584
L E L+ KL EK++ + + E Q L DH ++ S E +G
Sbjct: 595 ELMKEYNYLKEKLLQCEKEKAEREVIVREFQE-------ELVDHLKTFSI---SESPLEG 644
Query: 585 TVDKCCHLQENLNSHVLILSLQLSKAES-----KFRVLETELHYTGEALKEKALVFEH-- 637
T +L E S + +++ E K L + L+YT + +++K E
Sbjct: 645 TSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEA 704
Query: 638 -----------------------VQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFC 674
+L Q +M + K K +N + E C
Sbjct: 705 TGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSEC 764
Query: 675 -QLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKML 733
L K N +L Q+L R N+Q +C K LE+D KML
Sbjct: 765 VNLAKDNEVLHQELLSMR----------------------NVQEKCEK----LEKDKKML 798
Query: 734 VNELTHSK---EKEC-------QYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASS 783
E+ + K EK+ +Y+ E ER AV+++++ + L K + + L+ +
Sbjct: 799 EEEVLNLKTHMEKDMVELGKLQEYKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLN 856
Query: 784 RHCT----YLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMR 839
+ T E ++D K +M++ ++E+ +L + E A ++ N M +
Sbjct: 857 KDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL------EEFKEAFAGAVKANNSMSK 910
Query: 840 KIIK 843
K++K
Sbjct: 911 KLMK 914
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 201 bits (510), Expect = 3e-51
Identities = 159/530 (30%), Positives = 278/530 (52%), Gaps = 37/530 (6%)
Query: 355 NKASVLQKRLSEKEEIKSQ----LKHETLELEKELCSLRFAIQQEKKK--RRNVEELHQK 408
N +S++ L + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 318 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 377
Query: 409 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 467
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 378 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 437
Query: 468 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQ 525
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ NE+ + +T+A YS Q
Sbjct: 438 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 497
Query: 526 LAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 585
L L EN L S+LEK++ + +RLE E++S L A+ ++++ ++D EL
Sbjct: 498 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 556
Query: 586 VDKCCHLQENLNSHVL-----ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQS 640
D H + N L +L+ Q+ KA KF L+ +L T +AL+EK L VQ
Sbjct: 557 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 616
Query: 641 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 696
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 617 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 676
Query: 697 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREV 756
+E ++NI C +EN + + LLEE NK L+ E + KEK Q EKEKAEREV
Sbjct: 677 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 726
Query: 757 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 816
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 727 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785
Query: 817 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 866
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 786 LFELISLLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 828
Score = 65.5 bits (158), Expect = 2e-10
Identities = 154/724 (21%), Positives = 276/724 (38%), Gaps = 181/724 (25%)
Query: 225 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 284
+N+ + +K + AE +L++ASE +Q+RL+ EN QP
Sbjct: 374 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP--------------- 418
Query: 285 IQSSQTVSEDGDSLCCNC---KNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDN 341
Q SQ+ + D++ N K++ +L + E+ L K KK K +TE+ N
Sbjct: 419 -QDSQSYGKKKDAMYGNFMLKKDIAML--KEELYAIKNDSLRKEKKYIQEIKSITEINAN 475
Query: 342 HCEQLRVKIRKLKNKASVLQKRL----SEKEEIKSQL---KHETLELEKELCSLRFA--- 391
+ +R+ + + + ++L +E + S+L KH LE E+ SL +
Sbjct: 476 FEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLAT 535
Query: 392 -----------------------IQQEKKKRRNVEELHQK-----------------VRE 411
+ + +K N+ +L K ++
Sbjct: 536 AINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKG 595
Query: 412 KLRITEEQYRIEADVTKPIKPALKSAEVELK----TGGNNSNQVSETDEKEDLLHENRLM 467
KLR T + R + ++ L+ A+ +K N + S++ K++ L E R+
Sbjct: 596 KLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSL-EERIR 654
Query: 468 QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLA 527
Q E+ L LE+ +K + EIV H D L+ +E L E +
Sbjct: 655 QQELENLLLERQL----EDARKEGDNKEIVINIHRD---CLENGKEDLLEE------RNK 701
Query: 528 ALTDENTTLRSKL---EKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQG 584
L E L+ KL EK++ + + E Q L DH ++ S E +G
Sbjct: 702 ELMKEYNYLKEKLLQCEKEKAEREVIVREFQE-------ELVDHLKTFSI---SESPLEG 751
Query: 585 TVDKCCHLQENLNSHVLILSLQLSKAES-----KFRVLETELHYTGEALKEKALVFEH-- 637
T +L E S + +++ E K L + L+YT + +++K E
Sbjct: 752 TSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEA 811
Query: 638 -----------------------VQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFC 674
+L Q +M + K K +N + E C
Sbjct: 812 TGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSEC 871
Query: 675 -QLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKML 733
L K N +L Q+L R N+Q +C K LE+D KML
Sbjct: 872 VNLAKDNEVLHQELLSMR----------------------NVQEKCEK----LEKDKKML 905
Query: 734 VNELTHSK---EKEC-------QYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASS 783
E+ + K EK+ +Y+ E ER AV+++++ + L K + + L+ +
Sbjct: 906 EEEVLNLKTHMEKDMVELGKLQEYKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLN 963
Query: 784 RHCT----YLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMR 839
+ T E ++D K +M++ ++E+ +L + E A ++ N M +
Sbjct: 964 KDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL------EEFKEAFAGAVKANNSMSK 1017
Query: 840 KIIK 843
K++K
Sbjct: 1018 KLMK 1021
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 125 bits (315), Expect = 1e-28
Identities = 113/413 (27%), Positives = 201/413 (48%), Gaps = 41/413 (9%)
Query: 456 EKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETL 515
E ED + + + + LR E+ E++ + E + + ++ K + L
Sbjct: 129 EVEDPAVKGAVQRKNVQTLRAEQTLPVALEEEQERCERSEKKQSQVKEGNNTNKSEKIQL 188
Query: 516 AETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSK 575
+E + C+S AA +L KQR+ G+ T Q + +L +HD+ +
Sbjct: 189 SENV-CHSTSSAAA--------DRLTKQRKVGK---TYPQQFPKKLKK---EHDREELER 233
Query: 576 RDQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVF 635
++++ ++ V+ + L V L ++L + + L Y+ ++K + F
Sbjct: 234 KEKQ--YKKEVEA-----KQLEPTVQSLDMKLKTTRNTPNQINQSLRYS----QKKVIGF 282
Query: 636 EHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQQLDDAR 691
+ ++L Q Q Q+K++++MY++ + K +ER CQL+ +N ++QQLDD
Sbjct: 283 RNSPNDLSQTQQQIKEMKEMYENAEAKVNNSTGKWSCVEERICQLQHENPCIEQQLDDVH 342
Query: 692 NKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEK 751
K D++E + NIQ E K L+LEE NK L+NE H KE QYE+EK
Sbjct: 343 QKEDHKE-IVTNIQRGF--------IESGKKDLMLEEKNKKLMNECDHLKESLFQYEREK 393
Query: 752 AEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQ 811
AER V VRQLQQ+ D L K + ++ L+ S + L+ Q +KKL Q+ SQF +
Sbjct: 394 AERVVVVRQLQQEAADSLKKLTMLESPLEGISHYHINLDE-TQVPKKKLFQVESQFDDFM 452
Query: 812 DQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQ 864
+ A + + Q + E + M+K ++++ E++E +K+L+ L L+
Sbjct: 453 AEKEAVSSKCVNLAKEIQVFQQELLSMKK-VQQECEKLEEDKKMLEEEILNLK 504
Score = 46.2 bits (108), Expect = 1e-04
Identities = 106/495 (21%), Positives = 202/495 (40%), Gaps = 70/495 (14%)
Query: 202 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 261
RI G G P P+LK + E ++ + A + K+VQT AEQ L +A E EQ+R
Sbjct: 108 RIVNGKGKGP--PAKHPSLKPSTEVEDPAVKGAVQRKNVQTLR-AEQTLPVALEEEQERC 164
Query: 262 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 321
E E Q QVK + + + IQ S+ V S + L Q
Sbjct: 165 ERSEKKQSQVKE--GNNTNKSEKIQLSENVCHSTSSAAAD-----RLTKQR--------- 208
Query: 322 LLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKS-QLKHETLE 380
K+ KT+ +Q K++K ++ + +K K+E+++ QL+
Sbjct: 209 --KVGKTY-------------PQQFPKKLKKEHDREELERKEKQYKKEVEAKQLEPTVQS 253
Query: 381 LEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVE 440
L+ +L + R Q + R QK R + K +K ++AE +
Sbjct: 254 LDMKLKTTRNTPNQINQSLR----YSQKKVIGFRNSPNDLSQTQQQIKEMKEMYENAEAK 309
Query: 441 LKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDTIK-NQNLEKKYL----KDF 494
+ N++ + S +E+ L HEN ++ ++ + ++D + N+++ ++ KD
Sbjct: 310 V---NNSTGKWSCVEERICQLQHENPCIEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDL 366
Query: 495 EIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEM 554
+ E+ K L + L E++ Y + A E + +L+++ + T +
Sbjct: 367 ML-----EEKNKKLMNECDHLKESLFQYEREKA----ERVVVVRQLQQEAADSLKKLTML 417
Query: 555 QSYRCRLNAALCDHDQSHSSKR---------DQELAFQGTV-DKCCHLQENLNSHVLILS 604
+S ++ + D++ K+ D +A + V KC +L + + L
Sbjct: 418 ESPLEGISHYHINLDETQVPKKKLFQVESQFDDFMAEKEAVSSKCVNLAKEIQVFQQEL- 476
Query: 605 LQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTME 664
L + K + + LE + E + E+ EL + Q ++++ +E
Sbjct: 477 LSMKKVQQECEKLEEDKKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLE 536
Query: 665 KCIEKQERFCQLKKQ 679
+ I QE+ + KKQ
Sbjct: 537 E-IHLQEQ-AEHKKQ 549
Score = 37.4 bits (85), Expect = 0.061
Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 19/160 (11%)
Query: 250 LEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLI 309
LE EG + Q K DD + + VS S C N I +
Sbjct: 417 LESPLEGISHYHINLDETQVPKKKLFQVESQFDDFMAEKEAVS----SKCVNLAKEIQVF 472
Query: 310 DQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEE 369
Q LL +KK C++L E K + L +I LK LS+ +E
Sbjct: 473 QQE---------LLSMKKVQQECEKLEEDK----KMLEEEILNLKTHMENSMVELSKLQE 519
Query: 370 IKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKV 409
KS+L ++ ++L + Q E KK+ +E+L++ +
Sbjct: 520 YKSELDERAMQAVEKLEEIHLQEQAEHKKQ--LEQLNKDI 557
>gi|239754871 PREDICTED: similar to Coiled-coil domain-containing
protein 144C [Homo sapiens]
Length = 264
Score = 124 bits (312), Expect = 3e-28
Identities = 71/172 (41%), Positives = 112/172 (65%), Gaps = 14/172 (8%)
Query: 389 RFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS 448
R ++QE++KR++ + L++K E+L+ EE+Y + ++ + +K LK+ +EL+T N
Sbjct: 91 RLTLKQEEEKRKDADMLYKKGSEELKRKEEEYGKDVEINQQLKRTLKTRAMELRTVRKNL 150
Query: 449 NQ-----------VSETDEKED-LLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDF 494
+Q +S + +KE LLHEN ++Q+EIA LRLE DTIK+QN EKKY +D
Sbjct: 151 DQTFGNLHSLRFEISLSHKKEKGLLHENSMLQEEIAMLRLELDTIKHQNEIKEKKYFEDI 210
Query: 495 EIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES 546
E VK +H++L KA+ NEE LA+T+ Y+GQL+ LT EN L S+L+ + +
Sbjct: 211 ESVKEEHDNLLKAITLNEEALAKTVFQYNGQLSILTTENKMLSSELKNVKHN 262
Score = 32.3 bits (72), Expect = 2.0
Identities = 29/127 (22%), Positives = 57/127 (44%), Gaps = 23/127 (18%)
Query: 636 EHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKAD 695
E+ + LKQ++ + KD + +YK G +++ K+E + +++ + QQL +
Sbjct: 88 EYHRLTLKQEEEKRKDADMLYKKGSEELKR---KEEEY----GKDVEINQQL---KRTLK 137
Query: 696 NQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAERE 755
+ + ++ D NL H L E L+H KEK +E + E
Sbjct: 138 TRAMELRTVRKNLDQTFGNL------HSLRFE-------ISLSHKKEKGLLHENSMLQEE 184
Query: 756 VAVRQLQ 762
+A+ +L+
Sbjct: 185 IAMLRLE 191
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.333
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,628,880
Number of Sequences: 37866
Number of extensions: 1335460
Number of successful extensions: 14641
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 313
Number of HSP's successfully gapped in prelim test: 1076
Number of HSP's that attempted gapping in prelim test: 7013
Number of HSP's gapped (non-prelim): 4922
length of query: 868
length of database: 18,247,518
effective HSP length: 111
effective length of query: 757
effective length of database: 14,044,392
effective search space: 10631604744
effective search space used: 10631604744
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.