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Search of human proteins with 117190342
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117190342 PHD finger protein 2 [Homo sapiens]
(1096 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117190342 PHD finger protein 2 [Homo sapiens] 2213 0.0
gi|32698700 PHD finger protein 8 [Homo sapiens] 940 0.0
gi|90093355 jumonji C domain containing histone demethylase 1 ho... 593 e-169
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 248 3e-65
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 248 3e-65
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 237 4e-62
gi|38788260 bromodomain PHD finger transcription factor isoform ... 74 6e-13
gi|38788274 bromodomain PHD finger transcription factor isoform ... 74 6e-13
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 70 1e-11
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 65 5e-10
gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens] 65 5e-10
gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens] 65 5e-10
gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens] 65 5e-10
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens] 65 5e-10
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens] 65 5e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 59 2e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 59 2e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 59 2e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 59 2e-08
gi|125656165 THO complex 2 [Homo sapiens] 58 6e-08
gi|88759339 aster-associated protein [Homo sapiens] 58 6e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 57 1e-07
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 55 4e-07
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 55 4e-07
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 55 4e-07
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 55 5e-07
gi|169211979 PREDICTED: hypothetical protein [Homo sapiens] 53 2e-06
gi|239740940 PREDICTED: hypothetical protein XP_002344108 [Homo ... 53 2e-06
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 51 5e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 51 5e-06
>gi|117190342 PHD finger protein 2 [Homo sapiens]
Length = 1096
Score = 2213 bits (5734), Expect = 0.0
Identities = 1096/1096 (100%), Positives = 1096/1096 (100%)
Query: 1 MATVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKS 60
MATVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKS
Sbjct: 1 MATVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKS 60
Query: 61 TLKKKRTWHKHGPGQAPDVKPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEE 120
TLKKKRTWHKHGPGQAPDVKPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEE
Sbjct: 61 TLKKKRTWHKHGPGQAPDVKPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEE 120
Query: 121 HGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDY 180
HGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDY
Sbjct: 121 HGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDY 180
Query: 181 YYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYCLIC 240
YYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYCLIC
Sbjct: 181 YYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYCLIC 240
Query: 241 VKDSYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVD 300
VKDSYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVD
Sbjct: 241 VKDSYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVD 300
Query: 301 KCYKCIVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSL 360
KCYKCIVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSL
Sbjct: 301 KCYKCIVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSL 360
Query: 361 TQFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHED 420
TQFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHED
Sbjct: 361 TQFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHED 420
Query: 421 ELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATP 480
ELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATP
Sbjct: 421 ELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATP 480
Query: 481 PQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASP 540
PQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASP
Sbjct: 481 PQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASP 540
Query: 541 TIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKSKSE 600
TIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKSKSE
Sbjct: 541 TIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKSKSE 600
Query: 601 AKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTSPGVFG 660
AKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTSPGVFG
Sbjct: 601 AKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTSPGVFG 660
Query: 661 ALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLPTPVTK 720
ALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLPTPVTK
Sbjct: 661 ALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLPTPVTK 720
Query: 721 PKLDSAAYKSDDSSDEGSLHIDTDTKPGRNARVKKESGSSAAGILDLLQASEEVGALEYN 780
PKLDSAAYKSDDSSDEGSLHIDTDTKPGRNARVKKESGSSAAGILDLLQASEEVGALEYN
Sbjct: 721 PKLDSAAYKSDDSSDEGSLHIDTDTKPGRNARVKKESGSSAAGILDLLQASEEVGALEYN 780
Query: 781 PSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKS 840
PSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKS
Sbjct: 781 PSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKS 840
Query: 841 AGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDNPIFKSRSKKRKGSD 900
AGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDNPIFKSRSKKRKGSD
Sbjct: 841 AGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDNPIFKSRSKKRKGSD 900
Query: 901 DAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLT 960
DAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLT
Sbjct: 901 DAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLT 960
Query: 961 PNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSS 1020
PNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSS
Sbjct: 961 PNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSS 1020
Query: 1021 LADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKKGMATAKQ 1080
LADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKKGMATAKQ
Sbjct: 1021 LADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKKGMATAKQ 1080
Query: 1081 RLGKILKIHRNGKLLL 1096
RLGKILKIHRNGKLLL
Sbjct: 1081 RLGKILKIHRNGKLLL 1096
>gi|32698700 PHD finger protein 8 [Homo sapiens]
Length = 1024
Score = 940 bits (2429), Expect = 0.0
Identities = 533/1122 (47%), Positives = 697/1122 (62%), Gaps = 124/1122 (11%)
Query: 1 MATVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKS 60
MA+VPVYC+CRLPYDVTRFMIECD C+DWFHGSCVGVEEE+A DID+YHCPNCE HG S
Sbjct: 1 MASVPVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNCEVLHGPS 60
Query: 61 TLKKKRTWHKHGPGQAPDV---KPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGY 117
+KK+R G + D KPV+ GS F++ELRSRTF S+++V+ + G+QLT+ +
Sbjct: 61 IMKKRR-----GSSKGHDTHKGKPVKTGSPTFVRELRSRTFDSSDEVILKPTGNQLTVEF 115
Query: 118 MEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEF 177
+EE+ F+ PILV KKDGLG+ +P+P+F V DVE+YVG ++ +DV DVT+Q DCKMKL +F
Sbjct: 116 LEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVTRQADCKMKLGDF 175
Query: 178 VDYYYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYC 237
V YYYS R++VLNV +LEFSDTR+S+ VE P IV+KLSWVEN WP++ + +P V KYC
Sbjct: 176 VKYYYSGKREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEECVFERPNVQKYC 235
Query: 238 LICVKDSYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFAD 297
L+ V+DSYTDFHID GG S WYHVLKGEK FYLIRP +AN++L+E W S+SN +EMFF D
Sbjct: 236 LMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGD 295
Query: 298 QVDKCYKCIVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKL 357
QVDKCYKC VKQGQTLFIP+GWI+A LTPVDCLAF G+FLHSL++EMQ++AYE+E+RL
Sbjct: 296 QVDKCYKCSVKQGQTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLST 355
Query: 358 GSLTQFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAE 417
L +FPNFET CWY+GKH+L+ F+G ++ + +LV G K LN AFR+WT+K+AL +
Sbjct: 356 ADLFRFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPD 415
Query: 418 HEDELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIE 477
HEDE+PE + QLIKDLA+EIRL E+ + + + + + P I
Sbjct: 416 HEDEIPETVRTVQLIKDLAREIRLVEDIFQQNVGKTSNIFGLQRIF--------PAGSIP 467
Query: 478 ATPPQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRES 537
T P + + ++ PSK K KP +L ++KGK+S
Sbjct: 468 LTRP-------AHSTSVSMSRLSLPSKNGSKKKGLKPK------ELFKKAERKGKESSAL 514
Query: 538 ASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKS 597
+ +L++ ++ +AL K G K+ ++ + +D L++
Sbjct: 515 GPAGQLSYNLMDTYSHQAL------KTGSFQKAKFNITGACLNDSDDDSPDLDLD----- 563
Query: 598 KSEAKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTSPG 657
N P +LL K KS L+ ++ K + +L+ + +
Sbjct: 564 --------GNESPLALLMSNGSTKRVKS-LSKSRRTKIAKKVDKARLMAEQVM------- 607
Query: 658 VFGALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLPTP 717
DE++ SDD EL+IDE K + ++ K P
Sbjct: 608 ----------------EDEFDLDSDD-ELQIDE-------RLGKEKATLIIRPKFPRKLP 643
Query: 718 VTKPKLDSAAYKSDDSSDEGSLHID------TDTKPGRNARVKKESGSSAAGILDLLQAS 771
KP D + + G + D TD K +GS A GILDLL+AS
Sbjct: 644 RAKPCSDPNRVR-----EPGEVEFDIEEDYTTDEDMVEGVEGKLGNGSGAGGILDLLKAS 698
Query: 772 EEVGALEYNPSSQPPASPSTQEAIQGMLSMANLQASD-----SCLQTTWGAGQ--AKGSS 824
+VG +Y ++ PASPSTQEAIQGML MANLQ+S S LQ W GQ + GSS
Sbjct: 699 RQVGGPDYAALTEAPASPSTQEAIQGMLCMANLQSSSSSPATSSLQAWWTGGQDRSSGSS 758
Query: 825 LAAHGARKNGGGSGKSAGKRLLKRAAKNSVDLDDYEE-----EQDHLDACFKDSDYVYPS 879
+ G N S ++ GKR +KR A + ++ EE EQD L ACFKD++Y+YPS
Sbjct: 759 SSGLGTVSNSPASQRTPGKRPIKRPAYWRTESEEEEENASLDEQDSLGACFKDAEYIYPS 818
Query: 880 LESDEDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAA 939
LESD+D+P KSR KK+K SDDAP+SP ARV P++P+QDRPVREGTRVASIETGLAAAAA
Sbjct: 819 LESDDDDPALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGTRVASIETGLAAAAA 878
Query: 940 KLSQQEEQKSKKKKSAKRK-LTPNTTSP---STSTSISAGTTSTSTTPASTTPASTTPAS 995
KL+QQE QK++KKK K+K L P ++ S++ + + TP T +S P
Sbjct: 879 KLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDSNLSLTVPAPTVAATPQLVTSSSPLP-- 936
Query: 996 TSTASSQASQEGSSPEPPPESHSSSLADHEYTA-AGTFTGAQAGRTSQPMAPGVFLTQRR 1054
PEP E+ S SLADHEYTA F AQA R++ PMAPGVFLTQRR
Sbjct: 937 -------------PPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRR 983
Query: 1055 PSASSPNNNTAAKGKRTKKGMATAKQRLGKILKIHRNGKLLL 1096
PS S +N A +GKR KKG+ATAKQRLG+ILKIHRNGKLLL
Sbjct: 984 PSVGS-QSNQAGQGKRPKKGLATAKQRLGRILKIHRNGKLLL 1024
>gi|90093355 jumonji C domain containing histone demethylase 1
homolog D [Homo sapiens]
Length = 941
Score = 593 bits (1529), Expect = e-169
Identities = 344/813 (42%), Positives = 457/813 (56%), Gaps = 103/813 (12%)
Query: 5 PVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKSTLKK 64
PVYCVCR PYDV RFMIECD CKDWFHGSCVGVEE A DID+YHCPNC HG S +KK
Sbjct: 37 PVYCVCRQPYDVNRFMIECDICKDWFHGSCVGVEEHHAVDIDLYHCPNCAVLHGSSLMKK 96
Query: 65 KRTWHKHGPGQAPD-VKPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEEHGF 123
+R WH+H + D KPVQ G++ FIKELRSR FPSA++++ ++ GSQLT Y+E+HGF
Sbjct: 97 RRNWHRHDYTEIDDGSKPVQAGTRTFIKELRSRVFPSADEIIIKMHGSQLTQRYLEKHGF 156
Query: 124 TEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYS 183
PI+VPK D LGL +P+PTF V DVE YVG ++ +DV DV +Q D KM L +V Y+ +
Sbjct: 157 DVPIMVPKLDDLGLRLPSPTFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMN 216
Query: 184 TNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYCLICVKD 243
NR +VLNV +LEFSDT+MS VE PDI KKLSWVENYWPDD++ KP V KYCL+ V+D
Sbjct: 217 PNRPKVLNVISLEFSDTKMSELVEVPDIAKKLSWVENYWPDDSVFPKPFVQKYCLMGVQD 276
Query: 244 SYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVDKCY 303
SYTDFHID GG S WYHVL GEK FYLI+P N++ YE W S+ SE+FF D+VDKCY
Sbjct: 277 SYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTDENLARYESWSSSVTQSEVFFGDKVDKCY 336
Query: 304 KCIVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQF 363
KC+VKQG TLF+P+GWI+A LT DC+AF G+FLH+L++ MQ+R YE+E+RLK L +F
Sbjct: 337 KCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKF 396
Query: 364 PNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHEDELP 423
P FE CW++ K+LLE K + G Q +LVQG K L+ A + W KK+ ++EH E+P
Sbjct: 397 PFFEAICWFVAKNLLETLKELREDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFEIP 456
Query: 424 EHFKPSQLIKDLAKEIR-LSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQ 482
++ +P LIK+L+K IR + E K V+ + + VC R E SP +
Sbjct: 457 DNVRPGHLIKELSKVIRAIEEENGKPVKSQGIPI-----VCPVSRSSNEATSPYHS---- 507
Query: 483 SLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTI 542
++K +K R+ T
Sbjct: 508 ---------------------------------------------RRKMRKLRDHNVRTP 522
Query: 543 PNLDLLEAHTKEALTKMEP-PKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKSKSEA 601
NLD+LE HT+E L ++E P + S L+ K H+Q S +
Sbjct: 523 SNLDILELHTREVLKRLEMCPWEEDILSSKLN--GKFNKHLQ------------PSSTVP 568
Query: 602 KWKYKNSKPDSLLKMEEEQKLEKSPLAGNK-DNKFSFSFSNKKLLGSKALRPPTSPGVFG 660
+W+ K++ LL K E+ P A S + +K+ ++ S GV G
Sbjct: 569 EWRAKDNDLRLLLTNGRIIKDERQPFADQSLYTADSENEEDKRRTKKAKMKIEESSGVEG 628
Query: 661 ALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLPTPVTK 720
E+ KP+ + V + R +++ D+S D T
Sbjct: 629 VEH---EESQKPLNGFFTRVKSE----------LRSRSSGYSDISESEDS----GPECTA 671
Query: 721 PKLDSAAYKSDDSSDEGSLHIDTDTKPGRNARVKKESGSSAAGILDLLQASEEVGALEYN 780
K +S+ S DE I ++ K N + + LQ S++ E
Sbjct: 672 LKSIFTTEESESSGDEKKQEITSNFKEESNV------------MRNFLQKSQKPSRSEIP 719
Query: 781 PSSQPPASPST-QEAIQGMLSMANLQASDSCLQ 812
+ P S ST +EAIQGMLSMA L S +CLQ
Sbjct: 720 IKRECPTSTSTEEEAIQGMLSMAGLHYS-TCLQ 751
Score = 58.5 bits (140), Expect = 3e-08
Identities = 32/52 (61%), Positives = 37/52 (71%), Gaps = 4/52 (7%)
Query: 1041 SQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKKGMATAKQRLGKILKIHRNG 1092
S P+ P T+R S P +N A KGKR KKGMATAKQRLGKILK++RNG
Sbjct: 888 SVPLHP----TKRPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNG 935
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a
[Homo sapiens]
Length = 1336
Score = 248 bits (632), Expect = 3e-65
Identities = 123/297 (41%), Positives = 175/297 (58%), Gaps = 16/297 (5%)
Query: 91 KELRSRTFPSAEDVVARVPGSQLTLGYMEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVE 150
++LRS+ + D V + G Y++ P++ +KDGLG+ +P P F V DV+
Sbjct: 72 EKLRSQLYQG--DFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVK 129
Query: 151 NYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYS--TNRKRVLNVTNLEFSDTRMSSFVEP 208
VG R VDV DV QK +M + +FV YY + R ++ NV +LEFS T++ V+
Sbjct: 130 LLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKR 189
Query: 209 PDIVKKLSWVENYWPDD------------ALLAKPKVTKYCLICVKDSYTDFHIDSGGAS 256
P +V + WV+N WP A + PKV KYCL+ VK +TDFHID GG S
Sbjct: 190 PTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTS 249
Query: 257 AWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVDKCYKCIVKQGQTLFIP 316
WYHV +G K F+LI P N++LYE W + S++F D+V++C + +KQG T FIP
Sbjct: 250 VWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIP 309
Query: 317 SGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYM 373
SGWI+A TPVD L F G+ LHS +V MQ+R YE+E R ++ ++P + CWY+
Sbjct: 310 SGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYV 366
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 11/59 (18%)
Query: 20 MIECDACKDWFHGSCVGVEEEEAPDID----IYHCPNCEKTHGKSTLKKKRTWHKHGPG 74
++EC C + H C+ ++E E D + CP C H T K+KR GPG
Sbjct: 685 LMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKC--NHAGKTGKQKR-----GPG 736
Score = 33.1 bits (74), Expect = 1.5
Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 27/137 (19%)
Query: 411 KKQALAEHEDELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKE 470
KK+ + LP +L K+L EI+ +EN ++ E S+ +G+ E +
Sbjct: 930 KKKVKMRRKRRLPNKELSRELSKELNHEIQRTEN---SLANENQQPIKSEPESEGE-EPK 985
Query: 471 EPPSPIEAT---------PPQSLLEKV--SKKKTPKTVKMPKPSKIPKPPK--------- 510
PP E P+ L ++ S + P+ + P PS PPK
Sbjct: 986 RPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPS--VSPPKCIQMERHVI 1043
Query: 511 -PPKPPRPPKTLKLKDG 526
PP PP +L L DG
Sbjct: 1044 RPPPISPPPDSLPLDDG 1060
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b
[Homo sapiens]
Length = 1265
Score = 248 bits (632), Expect = 3e-65
Identities = 123/297 (41%), Positives = 175/297 (58%), Gaps = 16/297 (5%)
Query: 91 KELRSRTFPSAEDVVARVPGSQLTLGYMEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVE 150
++LRS+ + D V + G Y++ P++ +KDGLG+ +P P F V DV+
Sbjct: 41 EKLRSQLYQG--DFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVK 98
Query: 151 NYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYS--TNRKRVLNVTNLEFSDTRMSSFVEP 208
VG R VDV DV QK +M + +FV YY + R ++ NV +LEFS T++ V+
Sbjct: 99 LLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKR 158
Query: 209 PDIVKKLSWVENYWPDD------------ALLAKPKVTKYCLICVKDSYTDFHIDSGGAS 256
P +V + WV+N WP A + PKV KYCL+ VK +TDFHID GG S
Sbjct: 159 PTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTS 218
Query: 257 AWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVDKCYKCIVKQGQTLFIP 316
WYHV +G K F+LI P N++LYE W + S++F D+V++C + +KQG T FIP
Sbjct: 219 VWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIP 278
Query: 317 SGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYM 373
SGWI+A TPVD L F G+ LHS +V MQ+R YE+E R ++ ++P + CWY+
Sbjct: 279 SGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYV 335
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 11/59 (18%)
Query: 20 MIECDACKDWFHGSCVGVEEEEAPDID----IYHCPNCEKTHGKSTLKKKRTWHKHGPG 74
++EC C + H C+ ++E E D + CP C H T K+KR GPG
Sbjct: 654 LMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKC--NHAGKTGKQKR-----GPG 705
Score = 33.1 bits (74), Expect = 1.5
Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 27/137 (19%)
Query: 411 KKQALAEHEDELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKE 470
KK+ + LP +L K+L EI+ +EN ++ E S+ +G+ E +
Sbjct: 861 KKKVKMRRKRRLPNKELSRELSKELNHEIQRTEN---SLANENQQPIKSEPESEGE-EPK 916
Query: 471 EPPSPIEAT---------PPQSLLEKV--SKKKTPKTVKMPKPSKIPKPPK--------- 510
PP E P+ L ++ S + P+ + P PS PPK
Sbjct: 917 RPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPS--VSPPKCIQMERHVI 974
Query: 511 -PPKPPRPPKTLKLKDG 526
PP PP +L L DG
Sbjct: 975 RPPPISPPPDSLPLDDG 991
>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
Length = 1162
Score = 237 bits (605), Expect = 4e-62
Identities = 116/303 (38%), Positives = 174/303 (57%), Gaps = 14/303 (4%)
Query: 85 GSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEEHGFTEPILVPKKDGLGLAVPAPTF 144
G + F E + T + V + G + Y++ G +P++ DGLG+ +P P F
Sbjct: 34 GKRTFDLEEKLHTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDF 93
Query: 145 YVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYSTN--RKRVLNVTNLEFSDTRM 202
V+DV+ VG R VDV DV QK +M + ++ YY + R+++ NV +LEFS TR+
Sbjct: 94 TVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRL 153
Query: 203 SSFVEPPDIVKKLSWVENYWP----------DDALLAK--PKVTKYCLICVKDSYTDFHI 250
+ V+ P V + WV+N WP +A+L PKV KYCL+ V+ YTDFH+
Sbjct: 154 ENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHV 213
Query: 251 DSGGASAWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVDKCYKCIVKQG 310
D GG S WYH+ +G K F+LI P + N+ LYE W + ++F D+V C + +KQG
Sbjct: 214 DFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQG 273
Query: 311 QTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETAC 370
T IPSGWI+A TP D L F G+FLHS ++ MQ++ Y +E R ++ + ++P + C
Sbjct: 274 YTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYNIEDRTRVPNKFRYPFYYEMC 333
Query: 371 WYM 373
WY+
Sbjct: 334 WYV 336
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 74.3 bits (181), Expect = 6e-13
Identities = 27/57 (47%), Positives = 39/57 (68%)
Query: 6 VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKSTL 62
+YC+C+ PYD ++F I CD C++W+HG CVG+ + EA ID Y CP C+ T T+
Sbjct: 2725 LYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTV 2781
Score = 36.2 bits (82), Expect = 0.17
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 2/92 (2%)
Query: 968 TSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYT 1027
T + +A T ST+TT STT A T S S Q PP +S S A+ +
Sbjct: 2338 TPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQ 2397
Query: 1028 AAGTFTGAQAGRTSQPMAPGVFLTQRRPSASS 1059
A AQ +QP +P Q +P +
Sbjct: 2398 TAQ--PSAQPQPQTQPQSPAQPEVQTQPEVQT 2427
Score = 35.0 bits (79), Expect = 0.39
Identities = 45/182 (24%), Positives = 61/182 (33%), Gaps = 61/182 (33%)
Query: 781 PSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKS 840
P PPA PST +G G+ G G R GGG G
Sbjct: 77 PPPPPPAPPSTSAPGRG--------------------GRGGG------GGRTGGGGGGGH 110
Query: 841 AGKRLLKRAAKNSVDLDDYE------------------------------EEQDHLDACF 870
+ R A N V DD+E +E+D ++
Sbjct: 111 LARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDD 170
Query: 871 KDSDYVYPSLESDEDNPIFKSRSKKRKGSDDAPYSPT-ARVGPSVPRQDRPVREGTRVAS 929
DSDY +E D+D+ + + S R S YS T R P V R P+ E +
Sbjct: 171 DDSDYP-EEMEDDDDDASYCTESSFRSHS---TYSSTPGRRKPRVHRPRSPILEEKDIPP 226
Query: 930 IE 931
+E
Sbjct: 227 LE 228
Score = 33.9 bits (76), Expect = 0.87
Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 895 KRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGL--AAAAAKLSQQEEQKSKKK 952
+RKG + P P P+Q PV T VA E L A A+ ++E+ ++ ++
Sbjct: 1984 QRKGLRSSALRPKR---PETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQ 2040
Query: 953 KSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTAS 1000
++ KR T +TST+ +T+++ +PA + S +T +
Sbjct: 2041 QAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGT 2088
Score = 33.5 bits (75), Expect = 1.1
Identities = 46/207 (22%), Positives = 82/207 (39%), Gaps = 34/207 (16%)
Query: 836 GSGKS----AGKRLLK--RAAKNSVD---------LDDYEEEQDHLDACFKDSDYVYPSL 880
GS KS A + +L+ RA K +D D E E D DA ++ SL
Sbjct: 543 GSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSL 602
Query: 881 ESDEDNPIFKSRSKKRKGSD-----DAPYSPTARVGPSVPRQDRPVREGTRVASIETGLA 935
E D D+ ++ K + D S +A +G + T S ET +
Sbjct: 603 EKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNT----------TNATSEETSPS 652
Query: 936 AAAAK---LSQQEEQKSKKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTT 992
+ LS+ + + +K +L + T S+ T++T+T+ S +
Sbjct: 653 EGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNKTCESSNTSATTTSIQPNLENSNS 712
Query: 993 PASTSTASSQASQEGSSPE-PPPESHS 1018
+ +++ S++++ PE ESH+
Sbjct: 713 SSELNSSQSESAKAADDPENGERESHT 739
Score = 31.2 bits (69), Expect = 5.6
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P +P P+ P P + T AA++ ++EE+K KS K+K+ +
Sbjct: 2655 PVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMI-S 2713
Query: 963 TTSPST 968
TTS T
Sbjct: 2714 TTSKET 2719
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 74.3 bits (181), Expect = 6e-13
Identities = 27/57 (47%), Positives = 39/57 (68%)
Query: 6 VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKSTL 62
+YC+C+ PYD ++F I CD C++W+HG CVG+ + EA ID Y CP C+ T T+
Sbjct: 2742 LYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTV 2798
Score = 36.2 bits (82), Expect = 0.17
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 2/92 (2%)
Query: 968 TSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYT 1027
T + +A T ST+TT STT A T S S Q PP +S S A+ +
Sbjct: 2212 TPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQ 2271
Query: 1028 AAGTFTGAQAGRTSQPMAPGVFLTQRRPSASS 1059
A AQ +QP +P Q +P +
Sbjct: 2272 TAQ--PSAQPQPQTQPQSPAQPEVQTQPEVQT 2301
Score = 35.0 bits (79), Expect = 0.39
Identities = 45/182 (24%), Positives = 61/182 (33%), Gaps = 61/182 (33%)
Query: 781 PSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKS 840
P PPA PST +G G+ G G R GGG G
Sbjct: 77 PPPPPPAPPSTSAPGRG--------------------GRGGG------GGRTGGGGGGGH 110
Query: 841 AGKRLLKRAAKNSVDLDDYE------------------------------EEQDHLDACF 870
+ R A N V DD+E +E+D ++
Sbjct: 111 LARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDD 170
Query: 871 KDSDYVYPSLESDEDNPIFKSRSKKRKGSDDAPYSPT-ARVGPSVPRQDRPVREGTRVAS 929
DSDY +E D+D+ + + S R S YS T R P V R P+ E +
Sbjct: 171 DDSDYP-EEMEDDDDDASYCTESSFRSHS---TYSSTPGRRKPRVHRPRSPILEEKDIPP 226
Query: 930 IE 931
+E
Sbjct: 227 LE 228
Score = 33.9 bits (76), Expect = 0.87
Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 895 KRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGL--AAAAAKLSQQEEQKSKKK 952
+RKG + P P P+Q PV T VA E L A A+ ++E+ ++ ++
Sbjct: 1858 QRKGLRSSALRPKR---PETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQ 1914
Query: 953 KSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTAS 1000
++ KR T +TST+ +T+++ +PA + S +T +
Sbjct: 1915 QAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGT 1962
Score = 31.2 bits (69), Expect = 5.6
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P +P P+ P P + T AA++ ++EE+K KS K+K+ +
Sbjct: 2672 PVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMI-S 2730
Query: 963 TTSPST 968
TTS T
Sbjct: 2731 TTSKET 2736
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 70.1 bits (170), Expect = 1e-11
Identities = 137/594 (23%), Positives = 226/594 (38%), Gaps = 90/594 (15%)
Query: 377 LLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHEDELPEHFK-----PSQL 431
LL+ + KS K +P +Q NG KK+A + ++ E + P++
Sbjct: 50 LLDIYSFWLKSAK-VPERKLQA----NGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKK 104
Query: 432 IKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIE-ATPPQSLLEKVSK 490
AK + L + A E + SS+E D D E+++ P++ PQ+ K
Sbjct: 105 AAVPAKRVGLPPGKAAAKASESS---SSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPP 161
Query: 491 KKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTIPNLDLLEA 550
KK + S +PPK KP P T+K + K A+P I N +A
Sbjct: 162 KKAKSSDSDSDSSSEDEPPKNQKPKITPVTVK----AQTKAPPKPARAAPKIAN---GKA 214
Query: 551 HTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKSKSEAKWKYKNSKP 610
+ + + + + P K V Q V + ++ T ++ +S
Sbjct: 215 ASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQ-VVAKAPVKAATTPTRKS-----SSSE 268
Query: 611 DSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTSPGVFGAL--QNFKE- 667
DS EEEQ K P+ NK +S ++ PP++P +L Q K+
Sbjct: 269 DSSSDEEEEQ---KKPMK-NKPGPYS------------SVPPPSAPPPKKSLGTQPPKKA 312
Query: 668 -DKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLPTPVTK-PKLDS 725
+K +PV + E SD+ + +E +K P KAV+ TK P
Sbjct: 313 VEKQQPV-ESSEDSSDESDSSSEE-----EKKPP---------TKAVVSKATTKPPPAKK 357
Query: 726 AAYKSDDSSDEGSLHIDTDTKPGRNARVKKESGSSAAGILDLLQASEEVGALEYNPSSQP 785
AA S DSSD S + D P + A K S + A +P+ +P
Sbjct: 358 AAESSSDSSDSDS--SEDDEAPSKPAGTTKNSSNKPA-------------VTTKSPAVKP 402
Query: 786 PASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKSAGKRL 845
A+P Q G + S S + + + + K + A K + S +
Sbjct: 403 AAAPK-QPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQ 461
Query: 846 LKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDNPIFKSRSKKRK-------G 898
+ +++S D ++ + K + P + P + +KK K
Sbjct: 462 APQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSS 521
Query: 899 SDDAPYSPTARV-GPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKK 951
SDD+ ++ G PR P GT + + G AAK S++EE++ KK
Sbjct: 522 SDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNG---KAAKNSEEEEEEKKK 572
Score = 52.8 bits (125), Expect = 2e-06
Identities = 86/329 (26%), Positives = 121/329 (36%), Gaps = 47/329 (14%)
Query: 411 KKQALAEHEDELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKE 470
K+Q + ED E S+ K + +S+ +K + +SSD E +
Sbjct: 315 KQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDD 374
Query: 471 EPPSPIEATPPQSLLEKVSKKKTPKTVKMP--KPSKIPKPPKPPKPPRPPKTLKLKDGGK 528
E PS T K S K T K P KP+ PK P GG+
Sbjct: 375 EAPSKPAGTT------KNSSNKPAVTTKSPAVKPAAAPKQPV--------------GGGQ 414
Query: 529 KKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKAT-KSVLSVPNKDVVH------ 581
K + +S+S + E TK KM K KAT K+ LS+P K
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTK----KMVATTKPKATAKAALSLPAKQAPQGSRDSS 470
Query: 582 MQNDVERLEIREQTKSKSEAKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSN 641
+D E E+ SKS K K + + K K+ + + + S
Sbjct: 471 SDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEE 530
Query: 642 KKLLGSKALRP--PTSPGVFG-ALQNFKEDKPKPVRDEYE-----YVSDDGELKIDEFPI 693
+KL G + RP P + G QN K K +E + VS G LK
Sbjct: 531 EKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLK------ 584
Query: 694 RRKKNAPKRDLSFLLDKKAVLPTPVTKPK 722
+RK+N ++ KK L TP T PK
Sbjct: 585 KRKQNEAAKEAETPQAKKIKLQTPNTFPK 613
Score = 44.7 bits (104), Expect = 5e-04
Identities = 79/378 (20%), Positives = 139/378 (36%), Gaps = 38/378 (10%)
Query: 710 KKAVLPTP-VTKPKLDSAAYKSDDSSDEGSLHIDTDTKPGRNARVKKESGSSAAGILDLL 768
KKA +P V P +AA S+ SS E S D + + K + A
Sbjct: 103 KKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPK 162
Query: 769 QASEEVGALEYNPSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAH 828
+A + + +PP + + ++ ++A Q K A
Sbjct: 163 KAKSSDSDSDSSSEDEPPKNQKPK------ITPVTVKA------------QTKAPPKPAR 204
Query: 829 GARKNGGGSGKSAGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDNPI 888
A K G S+ ++ +S DD EEE+ P + P+
Sbjct: 205 AAPKIANGKAASSSS-----SSSSSSSSDDSEEEK-----AAATPKKTVPKKQVVAKAPV 254
Query: 889 FKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAK-LSQQEEQ 947
+ + RK S S P +++P +S+ A K L Q +
Sbjct: 255 KAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP----GPYSSVPPPSAPPPKKSLGTQPPK 310
Query: 948 KS-KKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQE 1006
K+ +K++ + + S S+S T + A+T P A+ S++ S S
Sbjct: 311 KAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDS 370
Query: 1007 GSSPEPPPESHSSSLADHEYTAAGTFTGA--QAGRTSQPMAPG-VFLTQRRPSASSPNNN 1063
E P + ++ A T + A A QP+ G LT++ S+SS +
Sbjct: 371 SEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES 430
Query: 1064 TAAKGKRTKKGMATAKQR 1081
++++ ++TKK +AT K +
Sbjct: 431 SSSEEEKTKKMVATTKPK 448
Score = 35.8 bits (81), Expect = 0.23
Identities = 51/257 (19%), Positives = 95/257 (36%), Gaps = 40/257 (15%)
Query: 819 QAKGSSLAAHGARKNGGGSGKSAGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYP 878
Q + AA A++ G GK+A K +++ S D DD E+++ V P
Sbjct: 98 QGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQ-----PVQKGVKP 152
Query: 879 SLESDEDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAA 938
++ + P KK K SD S + P+ +P
Sbjct: 153 QAKAAKAPP------KKAKSSDSDSDSSSE---DEPPKNQKP--------------KITP 189
Query: 939 AKLSQQEEQKSKKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTP----- 993
+ Q + K ++A + S S+S+S S+ + + A+ TP T P
Sbjct: 190 VTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVV 249
Query: 994 -------ASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
A+T T S +S++ SS E + Y++ + ++ P
Sbjct: 250 AKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPP 309
Query: 1047 GVFLTQRRPSASSPNNN 1063
+ +++P SS +++
Sbjct: 310 KKAVEKQQPVESSEDSS 326
Score = 31.2 bits (69), Expect = 5.6
Identities = 50/235 (21%), Positives = 92/235 (39%), Gaps = 22/235 (9%)
Query: 839 KSAGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDY----VYPSLESDEDNPIFKSRSK 894
KS G + K+A + ++ E+ D D+ ++ S + + P K+
Sbjct: 302 KSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAES 361
Query: 895 KRKGSD----DAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSK 950
SD + +P+ G + ++P T+ +++ AAA K QK
Sbjct: 362 SSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVT-TKSPAVKP---AAAPKQPVGGGQKLL 417
Query: 951 KKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSP 1010
+K+ +S S S S+ T A+T P +T A+ S + QA Q GS
Sbjct: 418 TRKA--------DSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ-GSRD 468
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTA 1065
SSS + E T+ + + + AP + ++ A S N++++
Sbjct: 469 SSSDSDSSSSEEEEEKTSKSA-VKKKPQKVAGGAAPSKPASAKKGKAESSNSSSS 522
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 64.7 bits (156), Expect = 5e-10
Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 14/81 (17%)
Query: 6 VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDI----DIYHCPNC------EK 55
+YC+CR P++ RFMI CD C++WFHG CVG+ E + + Y CPNC ++
Sbjct: 269 LYCICRQPHN-NRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDE 327
Query: 56 THGKSTLKKKRTWHKHGPGQA 76
TH ++ +++ W PG A
Sbjct: 328 THSETADQQEAKWR---PGDA 345
>gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]
Length = 1189
Score = 64.7 bits (156), Expect = 5e-10
Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 14/81 (17%)
Query: 6 VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDI----DIYHCPNC------EK 55
+YC+CR P++ RFMI CD C++WFHG CVG+ E + + Y CPNC ++
Sbjct: 269 LYCICRQPHN-NRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDE 327
Query: 56 THGKSTLKKKRTWHKHGPGQA 76
TH ++ +++ W PG A
Sbjct: 328 THSETADQQEAKWR---PGDA 345
>gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens]
Length = 562
Score = 64.7 bits (156), Expect = 5e-10
Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 14/81 (17%)
Query: 6 VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDI----DIYHCPNC------EK 55
+YC+CR P++ RFMI CD C++WFHG CVG+ E + + Y CPNC ++
Sbjct: 269 LYCICRQPHN-NRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDE 327
Query: 56 THGKSTLKKKRTWHKHGPGQA 76
TH ++ +++ W PG A
Sbjct: 328 THSETADQQEAKWR---PGDA 345
>gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens]
Length = 562
Score = 64.7 bits (156), Expect = 5e-10
Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 14/81 (17%)
Query: 6 VYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDI----DIYHCPNC------EK 55
+YC+CR P++ RFMI CD C++WFHG CVG+ E + + Y CPNC ++
Sbjct: 269 LYCICRQPHN-NRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDE 327
Query: 56 THGKSTLKKKRTWHKHGPGQA 76
TH ++ +++ W PG A
Sbjct: 328 THSETADQQEAKWR---PGDA 345
>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
Length = 660
Score = 64.7 bits (156), Expect = 5e-10
Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 8/122 (6%)
Query: 5 PVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKSTLKK 64
P+YC+CR P D+ FMI CD C +WFHG C+ + E+ A I ++C C + K ++
Sbjct: 26 PIYCICRKP-DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRY 84
Query: 65 KRTWHKHGPGQAPDVKPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEEHGFT 124
+ + G D ++ E R P + + R GS +G M G
Sbjct: 85 RHKKSRERDGNERDSSEPRD-------EGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSA 137
Query: 125 EP 126
P
Sbjct: 138 SP 139
>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
Length = 656
Score = 64.7 bits (156), Expect = 5e-10
Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 8/122 (6%)
Query: 5 PVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKSTLKK 64
P+YC+CR P D+ FMI CD C +WFHG C+ + E+ A I ++C C + K ++
Sbjct: 26 PIYCICRKP-DINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRY 84
Query: 65 KRTWHKHGPGQAPDVKPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEEHGFT 124
+ + G D ++ E R P + + R GS +G M G
Sbjct: 85 RHKKSRERDGNERDSSEPRD-------EGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSA 137
Query: 125 EP 126
P
Sbjct: 138 SP 139
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 59.3 bits (142), Expect = 2e-08
Identities = 55/190 (28%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 902 APYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTP 961
AP +P P+ P++ P + G A K E + KK A ++L P
Sbjct: 616 APTTPKG-TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK----EPAPTTPKKPAPKELAP 670
Query: 962 NTTSPSTSTSIS--AGTT------STSTTPASTT---PASTTPASTSTASSQASQEGSSP 1010
TT TST+ A TT +T PA TT PA TTP + +S+ S ++
Sbjct: 671 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 730
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR 1070
EP S + E +A T + + P PGV T + P+A+ P T AK K
Sbjct: 731 EPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGV-PTTKTPAATKPEMTTTAKDKT 785
Query: 1071 TKKGMATAKQ 1080
T++ + T +
Sbjct: 786 TERDLRTTPE 795
Score = 44.3 bits (103), Expect = 6e-04
Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 11/167 (6%)
Query: 883 DEDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLS 942
+E P + + AP +P P+ P++ P + G A K
Sbjct: 528 EEPAPTTPKAAAPNTPKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-- 584
Query: 943 QQEEQKSKKKKSAKRKLTPNTTSPSTSTSIS--AGTTSTSTTPAS-TTPASTTPASTSTA 999
E + KK A ++L P TT TST+ A TT T P + PA TTP +
Sbjct: 585 --EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 642
Query: 1000 SSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
+ + + + EP P + A T T TS AP
Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGPTSTTSDKPAP 686
Score = 38.5 bits (88), Expect = 0.035
Identities = 36/171 (21%), Positives = 63/171 (36%), Gaps = 17/171 (9%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P T P+ P++ P T A ++ + K+ + P+
Sbjct: 333 PAPTTKEPAPTTPKEPAP-----------TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS 381
Query: 963 TTSP---STSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSS 1019
T+P + +T+ SA TT+ P +T A TTP S +++ + EP P +
Sbjct: 382 PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 441
Query: 1020 SLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR 1070
A T A T++ AP T + P+ ++P K+
Sbjct: 442 PAPTTPKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKK 489
Score = 36.6 bits (83), Expect = 0.13
Identities = 25/97 (25%), Positives = 37/97 (38%), Gaps = 2/97 (2%)
Query: 468 EKEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKD 525
+K P +P E P P+ +K+ +P T K P P+ P K P P T
Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 526 GGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPP 562
K+ + + +PT P K A T + P
Sbjct: 414 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450
Score = 35.0 bits (79), Expect = 0.39
Identities = 37/178 (20%), Positives = 68/178 (38%), Gaps = 5/178 (2%)
Query: 893 SKKRKGSDDAPYSPTARVGPSVPRQD-RPVREGTRVASIETGLAAAAAKLSQQEEQKSKK 951
+ K+ +D + +A+ S+ + + + ++V + T A K K
Sbjct: 158 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 217
Query: 952 KKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPE 1011
+ K + P+ +T SA TT P +T A TTP + +++ + E
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 277
Query: 1012 PPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGK 1069
P P + + A +A T A T + AP T + P+ ++P T K
Sbjct: 278 PAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAP---TTPKEPAPTTPKEPTPTTPK 331
Score = 35.0 bits (79), Expect = 0.39
Identities = 45/187 (24%), Positives = 64/187 (34%), Gaps = 25/187 (13%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P T + P+ P++ P T A K K + K
Sbjct: 232 PTPTTIKSAPTTPKEPAPTT---------TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 282
Query: 963 TTSPSTSTSISAGTT------STSTTPASTTP---ASTTPASTSTASSQASQEGSSPEPP 1013
T P+ +T+ SA TT +T PA TTP A TTP T ++ ++ EP
Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAPTTKEPA 341
Query: 1014 PESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKK 1073
P + A T A T + AP T + PS ++P TK
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP---TTTKEPSPTTPKEPAPT---TTKS 395
Query: 1074 GMATAKQ 1080
T K+
Sbjct: 396 APTTTKE 402
Score = 35.0 bits (79), Expect = 0.39
Identities = 36/144 (25%), Positives = 50/144 (34%), Gaps = 12/144 (8%)
Query: 443 ENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKP 502
E A + T S + P P TP + K+ TP T K P P
Sbjct: 277 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPTPTTPKEPAP 335
Query: 503 S------KIPKPPKPPKPPRPPKTLKLKDG---GKKKGKKSRESASPTIPNLDLLEAHTK 553
+ PK P P P +P T + K+ + + SPT P + TK
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK-EPAPTTTK 394
Query: 554 EALTKMEPPKKGKATKSVLSVPNK 577
A T + P TKS + P +
Sbjct: 395 SAPTTTKEPAP-TTTKSAPTTPKE 417
Score = 35.0 bits (79), Expect = 0.39
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 4/103 (3%)
Query: 906 PTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKL---TPN 962
PT + + P++ T A+ A K ++++ + + + +A K+ T
Sbjct: 750 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT 809
Query: 963 TTSPSTSTSISAGTTS-TSTTPASTTPASTTPASTSTASSQAS 1004
TT +T + I+A TT TSTT TTP T T+T + + +
Sbjct: 810 TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852
Score = 34.7 bits (78), Expect = 0.51
Identities = 34/141 (24%), Positives = 46/141 (32%), Gaps = 31/141 (21%)
Query: 434 DLAKEIRLSENASKAVRPEVNTVASSDEVCDGDRE--KEEPPSPIEATPPQSLL--EKVS 489
D +KE L+ N V + T + DG + + IE T + L KV
Sbjct: 135 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 194
Query: 490 KKKTPK---------------------------TVKMPKPSKIPKPPKPPKPPRPPKTLK 522
K TPK T K P P+ I P PK P P T
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 523 LKDGGKKKGKKSRESASPTIP 543
K+ + + +PT P
Sbjct: 255 APTTPKEPAPTTTKEPAPTTP 275
Score = 34.7 bits (78), Expect = 0.51
Identities = 32/117 (27%), Positives = 44/117 (37%), Gaps = 14/117 (11%)
Query: 469 KEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP---------PKPPKPPRP 517
KE P+ ++ P P+ +K+ P T K P P+ KP P PK P P
Sbjct: 401 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 460
Query: 518 PKTLK-LKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLS 573
T K K+ + + +PT P L T E L P K T L+
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKETAPTTPK--KLTPTTPEKLAPTTPEKPAPTTPEELA 515
Score = 34.7 bits (78), Expect = 0.51
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 8/97 (8%)
Query: 472 PPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP----PKPPKPPRPPKTLKLKD 525
P +P E P P+ K+ P T K P P+ KP PK P P P +T
Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 487
Query: 526 GGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPP 562
KK + E +PT P + A T E P
Sbjct: 488 --KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522
Score = 33.9 bits (76), Expect = 0.87
Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 8/95 (8%)
Query: 451 PEVNTVASSDEVCDGDREKEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP 508
PE + +E+ E+ P +P E P P++ K+ P T K P P+
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT----T 558
Query: 509 PKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTIP 543
PK P P P +T G + + +PT P
Sbjct: 559 PKEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTP 591
Score = 33.5 bits (75), Expect = 1.1
Identities = 37/178 (20%), Positives = 62/178 (34%), Gaps = 14/178 (7%)
Query: 912 PSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTTSPSTSTS 971
PS+P +E + + ET + + ++ K+K+ K T + S
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 972 ISAGTTSTSTTPASTT----PASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYT 1027
TP + T PA TTP + + + + EP P + S+ +
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 1028 AAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR-----TKKGMATAKQ 1080
A T A T + AP T + P+ ++P K TK T K+
Sbjct: 248 APTTTKSAPT--TPKEPAP---TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 469 KEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKP-PKPPKPPRPPKTLKLKDGG 527
K P +P E P + K P T K P P+ +P P PK P P T +
Sbjct: 238 KSAPTTPKEPAP-------TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 290
Query: 528 KKKGKKSRESASPTIP 543
K + + +PT P
Sbjct: 291 TKSAPTTPKEPAPTTP 306
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 11/118 (9%)
Query: 458 SSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVK-MPKPSKIPKPPKPPKPPR 516
++ EV KE P+ I +P +S E +S + TPK ++ PK +P K P +
Sbjct: 719 TTSEVSTPTTTKE--PTTIHKSPDESTPE-LSAEPTPKALENSPKEPGVP-TTKTPAATK 774
Query: 517 PPKTLKLKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSV 574
P T KD ++ ++ + P + TKE T E + K T + V
Sbjct: 775 PEMTTTAKDKTTERDLRTTPETTTAAPKM------TKETATTTEKTTESKITATTTQV 826
Score = 33.1 bits (74), Expect = 1.5
Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 10/146 (6%)
Query: 942 SQQEEQKSKKKKSAKRKL--TPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTA 999
++ E + K K+ +R L TP TT+ + + TT+ TT + T +T ST+T
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT- 831
Query: 1000 SSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQ-AGRTSQPMAPGVFLTQRRPSAS 1058
+ ++P +++LA T T T + + + P T + +
Sbjct: 832 ------QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP 885
Query: 1059 SPNNNTAAKGKRTKKGMATAKQRLGK 1084
P T A K T R+ K
Sbjct: 886 KPQKPTKAPKKPTSTKKPKTMPRVRK 911
Score = 32.7 bits (73), Expect = 1.9
Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 10/152 (6%)
Query: 905 SPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTT 964
+PT P+ +P + + T A + K+ K P TT
Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400
Query: 965 S-PSTSTSISAGTT------STSTTPASTTP---ASTTPASTSTASSQASQEGSSPEPPP 1014
P+ +T+ SA TT +T+ PA TTP A TTP + + + + EP P
Sbjct: 401 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 460
Query: 1015 ESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
+ A T A T + + P
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 492
Score = 32.7 bits (73), Expect = 1.9
Identities = 40/182 (21%), Positives = 64/182 (35%), Gaps = 12/182 (6%)
Query: 884 EDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQ 943
E +P + AP +P + P+ P++ P A T A
Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTP-KEPAPTTTKKPAPTTPKEP 474
Query: 944 QEEQKSKKKKSAKRKLTPNTT---SPSTSTSISAGTTS--TSTTPASTTPASTTPASTST 998
+ + +KLTP T +P+T + T TTP TP TTP +
Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP--TTPEEPAP 532
Query: 999 ASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSAS 1058
+ +A+ + EP P + A T A T + AP T + P+ +
Sbjct: 533 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP---TTLKEPAPT 589
Query: 1059 SP 1060
+P
Sbjct: 590 TP 591
Score = 32.3 bits (72), Expect = 2.5
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 9/95 (9%)
Query: 469 KEEPPSPIEATPPQSL--LEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDG 526
K P +P E P + K+ P T K P P+ P PK P P
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP------ 306
Query: 527 GKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEP 561
KK + + +PT P + A T EP
Sbjct: 307 -KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340
Score = 32.0 bits (71), Expect = 3.3
Identities = 32/142 (22%), Positives = 47/142 (33%), Gaps = 8/142 (5%)
Query: 466 DREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKP-PKPPKPPRP----PKT 520
D+ P T P+ K+ P T K P+ + +P P PK P P P T
Sbjct: 613 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672
Query: 521 LK--LKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKME-PPKKGKATKSVLSVPNK 577
K K + + +PT P K A T E PP + +
Sbjct: 673 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 732
Query: 578 DVVHMQNDVERLEIREQTKSKS 599
+H D E+ + K+
Sbjct: 733 TTIHKSPDESTPELSAEPTPKA 754
Score = 31.2 bits (69), Expect = 5.6
Identities = 31/156 (19%), Positives = 50/156 (32%), Gaps = 6/156 (3%)
Query: 897 KGSDDAPYSP----TARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKK 952
K + P P T P+ P++ P + A K K
Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 468
Query: 953 KSAKRKL--TPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSP 1010
+ K TP T+P+T ++ T PA TTP + + + +
Sbjct: 469 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 528
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
EP P + ++ + A T A T + AP
Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 59.3 bits (142), Expect = 2e-08
Identities = 55/190 (28%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 902 APYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTP 961
AP +P P+ P++ P + G A K E + KK A ++L P
Sbjct: 657 APTTPKG-TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK----EPAPTTPKKPAPKELAP 711
Query: 962 NTTSPSTSTSIS--AGTT------STSTTPASTT---PASTTPASTSTASSQASQEGSSP 1010
TT TST+ A TT +T PA TT PA TTP + +S+ S ++
Sbjct: 712 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 771
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR 1070
EP S + E +A T + + P PGV T + P+A+ P T AK K
Sbjct: 772 EPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGV-PTTKTPAATKPEMTTTAKDKT 826
Query: 1071 TKKGMATAKQ 1080
T++ + T +
Sbjct: 827 TERDLRTTPE 836
Score = 44.3 bits (103), Expect = 6e-04
Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 11/167 (6%)
Query: 883 DEDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLS 942
+E P + + AP +P P+ P++ P + G A K
Sbjct: 569 EEPAPTTPKAAAPNTPKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-- 625
Query: 943 QQEEQKSKKKKSAKRKLTPNTTSPSTSTSIS--AGTTSTSTTPAS-TTPASTTPASTSTA 999
E + KK A ++L P TT TST+ A TT T P + PA TTP +
Sbjct: 626 --EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 683
Query: 1000 SSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
+ + + + EP P + A T T TS AP
Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGPTSTTSDKPAP 727
Score = 38.5 bits (88), Expect = 0.035
Identities = 36/171 (21%), Positives = 63/171 (36%), Gaps = 17/171 (9%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P T P+ P++ P T A ++ + K+ + P+
Sbjct: 374 PAPTTKEPAPTTPKEPAP-----------TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS 422
Query: 963 TTSP---STSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSS 1019
T+P + +T+ SA TT+ P +T A TTP S +++ + EP P +
Sbjct: 423 PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 482
Query: 1020 SLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR 1070
A T A T++ AP T + P+ ++P K+
Sbjct: 483 PAPTTPKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKK 530
Score = 36.6 bits (83), Expect = 0.13
Identities = 25/97 (25%), Positives = 37/97 (38%), Gaps = 2/97 (2%)
Query: 468 EKEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKD 525
+K P +P E P P+ +K+ +P T K P P+ P K P P T
Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Query: 526 GGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPP 562
K+ + + +PT P K A T + P
Sbjct: 455 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491
Score = 35.0 bits (79), Expect = 0.39
Identities = 37/178 (20%), Positives = 68/178 (38%), Gaps = 5/178 (2%)
Query: 893 SKKRKGSDDAPYSPTARVGPSVPRQD-RPVREGTRVASIETGLAAAAAKLSQQEEQKSKK 951
+ K+ +D + +A+ S+ + + + ++V + T A K K
Sbjct: 199 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 258
Query: 952 KKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPE 1011
+ K + P+ +T SA TT P +T A TTP + +++ + E
Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 318
Query: 1012 PPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGK 1069
P P + + A +A T A T + AP T + P+ ++P T K
Sbjct: 319 PAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAP---TTPKEPAPTTPKEPTPTTPK 372
Score = 35.0 bits (79), Expect = 0.39
Identities = 45/187 (24%), Positives = 64/187 (34%), Gaps = 25/187 (13%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P T + P+ P++ P T A K K + K
Sbjct: 273 PTPTTIKSAPTTPKEPAPTT---------TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 323
Query: 963 TTSPSTSTSISAGTT------STSTTPASTTP---ASTTPASTSTASSQASQEGSSPEPP 1013
T P+ +T+ SA TT +T PA TTP A TTP T ++ ++ EP
Sbjct: 324 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAPTTKEPA 382
Query: 1014 PESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKK 1073
P + A T A T + AP T + PS ++P TK
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP---TTTKEPSPTTPKEPAPT---TTKS 436
Query: 1074 GMATAKQ 1080
T K+
Sbjct: 437 APTTTKE 443
Score = 35.0 bits (79), Expect = 0.39
Identities = 36/144 (25%), Positives = 50/144 (34%), Gaps = 12/144 (8%)
Query: 443 ENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKP 502
E A + T S + P P TP + K+ TP T K P P
Sbjct: 318 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPTPTTPKEPAP 376
Query: 503 S------KIPKPPKPPKPPRPPKTLKLKDG---GKKKGKKSRESASPTIPNLDLLEAHTK 553
+ PK P P P +P T + K+ + + SPT P + TK
Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK-EPAPTTTK 435
Query: 554 EALTKMEPPKKGKATKSVLSVPNK 577
A T + P TKS + P +
Sbjct: 436 SAPTTTKEPAP-TTTKSAPTTPKE 458
Score = 35.0 bits (79), Expect = 0.39
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 4/103 (3%)
Query: 906 PTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKL---TPN 962
PT + + P++ T A+ A K ++++ + + + +A K+ T
Sbjct: 791 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT 850
Query: 963 TTSPSTSTSISAGTTS-TSTTPASTTPASTTPASTSTASSQAS 1004
TT +T + I+A TT TSTT TTP T T+T + + +
Sbjct: 851 TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893
Score = 34.7 bits (78), Expect = 0.51
Identities = 34/141 (24%), Positives = 46/141 (32%), Gaps = 31/141 (21%)
Query: 434 DLAKEIRLSENASKAVRPEVNTVASSDEVCDGDRE--KEEPPSPIEATPPQSLL--EKVS 489
D +KE L+ N V + T + DG + + IE T + L KV
Sbjct: 176 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 235
Query: 490 KKKTPK---------------------------TVKMPKPSKIPKPPKPPKPPRPPKTLK 522
K TPK T K P P+ I P PK P P T
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 523 LKDGGKKKGKKSRESASPTIP 543
K+ + + +PT P
Sbjct: 296 APTTPKEPAPTTTKEPAPTTP 316
Score = 34.7 bits (78), Expect = 0.51
Identities = 32/117 (27%), Positives = 44/117 (37%), Gaps = 14/117 (11%)
Query: 469 KEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP---------PKPPKPPRP 517
KE P+ ++ P P+ +K+ P T K P P+ KP P PK P P
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 501
Query: 518 PKTLK-LKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLS 573
T K K+ + + +PT P L T E L P K T L+
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKETAPTTPK--KLTPTTPEKLAPTTPEKPAPTTPEELA 556
Score = 34.7 bits (78), Expect = 0.51
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 8/97 (8%)
Query: 472 PPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP----PKPPKPPRPPKTLKLKD 525
P +P E P P+ K+ P T K P P+ KP PK P P P +T
Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 528
Query: 526 GGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPP 562
KK + E +PT P + A T E P
Sbjct: 529 --KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563
Score = 33.9 bits (76), Expect = 0.87
Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 8/95 (8%)
Query: 451 PEVNTVASSDEVCDGDREKEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP 508
PE + +E+ E+ P +P E P P++ K+ P T K P P+
Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT----T 599
Query: 509 PKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTIP 543
PK P P P +T G + + +PT P
Sbjct: 600 PKEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTP 632
Score = 33.5 bits (75), Expect = 1.1
Identities = 37/178 (20%), Positives = 62/178 (34%), Gaps = 14/178 (7%)
Query: 912 PSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTTSPSTSTS 971
PS+P +E + + ET + + ++ K+K+ K T + S
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 972 ISAGTTSTSTTPASTT----PASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYT 1027
TP + T PA TTP + + + + EP P + S+ +
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 1028 AAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR-----TKKGMATAKQ 1080
A T A T + AP T + P+ ++P K TK T K+
Sbjct: 289 APTTTKSAPT--TPKEPAP---TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 469 KEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKP-PKPPKPPRPPKTLKLKDGG 527
K P +P E P + K P T K P P+ +P P PK P P T +
Sbjct: 279 KSAPTTPKEPAP-------TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 331
Query: 528 KKKGKKSRESASPTIP 543
K + + +PT P
Sbjct: 332 TKSAPTTPKEPAPTTP 347
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 11/118 (9%)
Query: 458 SSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVK-MPKPSKIPKPPKPPKPPR 516
++ EV KE P+ I +P +S E +S + TPK ++ PK +P K P +
Sbjct: 760 TTSEVSTPTTTKE--PTTIHKSPDESTPE-LSAEPTPKALENSPKEPGVP-TTKTPAATK 815
Query: 517 PPKTLKLKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSV 574
P T KD ++ ++ + P + TKE T E + K T + V
Sbjct: 816 PEMTTTAKDKTTERDLRTTPETTTAAPKM------TKETATTTEKTTESKITATTTQV 867
Score = 33.1 bits (74), Expect = 1.5
Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 10/146 (6%)
Query: 942 SQQEEQKSKKKKSAKRKL--TPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTA 999
++ E + K K+ +R L TP TT+ + + TT+ TT + T +T ST+T
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT- 872
Query: 1000 SSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQ-AGRTSQPMAPGVFLTQRRPSAS 1058
+ ++P +++LA T T T + + + P T + +
Sbjct: 873 ------QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP 926
Query: 1059 SPNNNTAAKGKRTKKGMATAKQRLGK 1084
P T A K T R+ K
Sbjct: 927 KPQKPTKAPKKPTSTKKPKTMPRVRK 952
Score = 32.7 bits (73), Expect = 1.9
Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 10/152 (6%)
Query: 905 SPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTT 964
+PT P+ +P + + T A + K+ K P TT
Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441
Query: 965 S-PSTSTSISAGTT------STSTTPASTTP---ASTTPASTSTASSQASQEGSSPEPPP 1014
P+ +T+ SA TT +T+ PA TTP A TTP + + + + EP P
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 501
Query: 1015 ESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
+ A T A T + + P
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 533
Score = 32.7 bits (73), Expect = 1.9
Identities = 40/182 (21%), Positives = 64/182 (35%), Gaps = 12/182 (6%)
Query: 884 EDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQ 943
E +P + AP +P + P+ P++ P A T A
Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTP-KEPAPTTTKKPAPTTPKEP 515
Query: 944 QEEQKSKKKKSAKRKLTPNTT---SPSTSTSISAGTTS--TSTTPASTTPASTTPASTST 998
+ + +KLTP T +P+T + T TTP TP TTP +
Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP--TTPEEPAP 573
Query: 999 ASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSAS 1058
+ +A+ + EP P + A T A T + AP T + P+ +
Sbjct: 574 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP---TTLKEPAPT 630
Query: 1059 SP 1060
+P
Sbjct: 631 TP 632
Score = 32.3 bits (72), Expect = 2.5
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 9/95 (9%)
Query: 469 KEEPPSPIEATPPQSL--LEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDG 526
K P +P E P + K+ P T K P P+ P PK P P
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP------ 347
Query: 527 GKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEP 561
KK + + +PT P + A T EP
Sbjct: 348 -KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381
Score = 32.0 bits (71), Expect = 3.3
Identities = 32/142 (22%), Positives = 47/142 (33%), Gaps = 8/142 (5%)
Query: 466 DREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKP-PKPPKPPRP----PKT 520
D+ P T P+ K+ P T K P+ + +P P PK P P P T
Sbjct: 654 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713
Query: 521 LK--LKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKME-PPKKGKATKSVLSVPNK 577
K K + + +PT P K A T E PP + +
Sbjct: 714 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 773
Query: 578 DVVHMQNDVERLEIREQTKSKS 599
+H D E+ + K+
Sbjct: 774 TTIHKSPDESTPELSAEPTPKA 795
Score = 31.2 bits (69), Expect = 5.6
Identities = 31/156 (19%), Positives = 50/156 (32%), Gaps = 6/156 (3%)
Query: 897 KGSDDAPYSP----TARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKK 952
K + P P T P+ P++ P + A K K
Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 509
Query: 953 KSAKRKL--TPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSP 1010
+ K TP T+P+T ++ T PA TTP + + + +
Sbjct: 510 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 569
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
EP P + ++ + A T A T + AP
Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 59.3 bits (142), Expect = 2e-08
Identities = 55/190 (28%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 902 APYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTP 961
AP +P P+ P++ P + G A K E + KK A ++L P
Sbjct: 709 APTTPKG-TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK----EPAPTTPKKPAPKELAP 763
Query: 962 NTTSPSTSTSIS--AGTT------STSTTPASTT---PASTTPASTSTASSQASQEGSSP 1010
TT TST+ A TT +T PA TT PA TTP + +S+ S ++
Sbjct: 764 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 823
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR 1070
EP S + E +A T + + P PGV T + P+A+ P T AK K
Sbjct: 824 EPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGV-PTTKTPAATKPEMTTTAKDKT 878
Query: 1071 TKKGMATAKQ 1080
T++ + T +
Sbjct: 879 TERDLRTTPE 888
Score = 44.3 bits (103), Expect = 6e-04
Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 11/167 (6%)
Query: 883 DEDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLS 942
+E P + + AP +P P+ P++ P + G A K
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-- 677
Query: 943 QQEEQKSKKKKSAKRKLTPNTTSPSTSTSIS--AGTTSTSTTPAS-TTPASTTPASTSTA 999
E + KK A ++L P TT TST+ A TT T P + PA TTP +
Sbjct: 678 --EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735
Query: 1000 SSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
+ + + + EP P + A T T TS AP
Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGPTSTTSDKPAP 779
Score = 38.5 bits (88), Expect = 0.035
Identities = 36/171 (21%), Positives = 63/171 (36%), Gaps = 17/171 (9%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P T P+ P++ P T A ++ + K+ + P+
Sbjct: 426 PAPTTKEPAPTTPKEPAP-----------TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS 474
Query: 963 TTSP---STSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSS 1019
T+P + +T+ SA TT+ P +T A TTP S +++ + EP P +
Sbjct: 475 PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 534
Query: 1020 SLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR 1070
A T A T++ AP T + P+ ++P K+
Sbjct: 535 PAPTTPKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKK 582
Score = 36.6 bits (83), Expect = 0.13
Identities = 25/97 (25%), Positives = 37/97 (38%), Gaps = 2/97 (2%)
Query: 468 EKEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKD 525
+K P +P E P P+ +K+ +P T K P P+ P K P P T
Sbjct: 447 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506
Query: 526 GGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPP 562
K+ + + +PT P K A T + P
Sbjct: 507 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543
Score = 36.2 bits (82), Expect = 0.17
Identities = 58/312 (18%), Positives = 108/312 (34%), Gaps = 26/312 (8%)
Query: 782 SSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKSA 841
S +PP T++ I+ S++ ++ + + S++ + KN + +
Sbjct: 95 SPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQ 154
Query: 842 GKRLLKRAAKNSVDLDDYEEEQ--DHLDACFKDSDY--VYPSLESDEDNPIFKSRSKKRK 897
K +K KN + D + + D+ P + + N + S K
Sbjct: 155 KKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKV----STSPK 210
Query: 898 GSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKR 957
+ P +P PS+P +E + + ET + + ++ K+K+
Sbjct: 211 ITTAKPINPR----PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 266
Query: 958 KLTPNTTSPSTSTSISAGTTSTSTTPASTT----PASTTPASTSTASSQASQEGSSPEPP 1013
K T + S TP + T PA TTP + + + + EP
Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 326
Query: 1014 PESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR--- 1070
P + S+ + A T A T + AP T + P+ ++P K
Sbjct: 327 PTTIKSAPTTPKEPAPTTTKSAPT--TPKEPAP---TTTKEPAPTTPKEPAPTTTKEPAP 381
Query: 1071 --TKKGMATAKQ 1080
TK T K+
Sbjct: 382 TTTKSAPTTPKE 393
Score = 35.0 bits (79), Expect = 0.39
Identities = 37/178 (20%), Positives = 68/178 (38%), Gaps = 5/178 (2%)
Query: 893 SKKRKGSDDAPYSPTARVGPSVPRQD-RPVREGTRVASIETGLAAAAAKLSQQEEQKSKK 951
+ K+ +D + +A+ S+ + + + ++V + T A K K
Sbjct: 251 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 310
Query: 952 KKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPE 1011
+ K + P+ +T SA TT P +T A TTP + +++ + E
Sbjct: 311 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 370
Query: 1012 PPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGK 1069
P P + + A +A T A T + AP T + P+ ++P T K
Sbjct: 371 PAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAP---TTPKEPAPTTPKEPTPTTPK 424
Score = 35.0 bits (79), Expect = 0.39
Identities = 45/187 (24%), Positives = 64/187 (34%), Gaps = 25/187 (13%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P T + P+ P++ P T A K K + K
Sbjct: 325 PTPTTIKSAPTTPKEPAPTT---------TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 375
Query: 963 TTSPSTSTSISAGTT------STSTTPASTTP---ASTTPASTSTASSQASQEGSSPEPP 1013
T P+ +T+ SA TT +T PA TTP A TTP T ++ ++ EP
Sbjct: 376 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAPTTKEPA 434
Query: 1014 PESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKK 1073
P + A T A T + AP T + PS ++P TK
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP---TTTKEPSPTTPKEPAPT---TTKS 488
Query: 1074 GMATAKQ 1080
T K+
Sbjct: 489 APTTTKE 495
Score = 35.0 bits (79), Expect = 0.39
Identities = 36/144 (25%), Positives = 50/144 (34%), Gaps = 12/144 (8%)
Query: 443 ENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKP 502
E A + T S + P P TP + K+ TP T K P P
Sbjct: 370 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPTPTTPKEPAP 428
Query: 503 S------KIPKPPKPPKPPRPPKTLKLKDG---GKKKGKKSRESASPTIPNLDLLEAHTK 553
+ PK P P P +P T + K+ + + SPT P + TK
Sbjct: 429 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK-EPAPTTTK 487
Query: 554 EALTKMEPPKKGKATKSVLSVPNK 577
A T + P TKS + P +
Sbjct: 488 SAPTTTKEPAP-TTTKSAPTTPKE 510
Score = 35.0 bits (79), Expect = 0.39
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 4/103 (3%)
Query: 906 PTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKL---TPN 962
PT + + P++ T A+ A K ++++ + + + +A K+ T
Sbjct: 843 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT 902
Query: 963 TTSPSTSTSISAGTTS-TSTTPASTTPASTTPASTSTASSQAS 1004
TT +T + I+A TT TSTT TTP T T+T + + +
Sbjct: 903 TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 945
Score = 34.7 bits (78), Expect = 0.51
Identities = 34/141 (24%), Positives = 46/141 (32%), Gaps = 31/141 (21%)
Query: 434 DLAKEIRLSENASKAVRPEVNTVASSDEVCDGDRE--KEEPPSPIEATPPQSLL--EKVS 489
D +KE L+ N V + T + DG + + IE T + L KV
Sbjct: 228 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 287
Query: 490 KKKTPK---------------------------TVKMPKPSKIPKPPKPPKPPRPPKTLK 522
K TPK T K P P+ I P PK P P T
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 347
Query: 523 LKDGGKKKGKKSRESASPTIP 543
K+ + + +PT P
Sbjct: 348 APTTPKEPAPTTTKEPAPTTP 368
Score = 34.7 bits (78), Expect = 0.51
Identities = 32/117 (27%), Positives = 44/117 (37%), Gaps = 14/117 (11%)
Query: 469 KEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP---------PKPPKPPRP 517
KE P+ ++ P P+ +K+ P T K P P+ KP P PK P P
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 518 PKTLK-LKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLS 573
T K K+ + + +PT P L T E L P K T L+
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKETAPTTPK--KLTPTTPEKLAPTTPEKPAPTTPEELA 608
Score = 34.7 bits (78), Expect = 0.51
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 8/97 (8%)
Query: 472 PPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP----PKPPKPPRPPKTLKLKD 525
P +P E P P+ K+ P T K P P+ KP PK P P P +T
Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580
Query: 526 GGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPP 562
KK + E +PT P + A T E P
Sbjct: 581 --KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615
Score = 33.9 bits (76), Expect = 0.87
Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 8/95 (8%)
Query: 451 PEVNTVASSDEVCDGDREKEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP 508
PE + +E+ E+ P +P E P P++ K+ P T K P P+
Sbjct: 596 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT----T 651
Query: 509 PKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTIP 543
PK P P P +T G + + +PT P
Sbjct: 652 PKEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTP 684
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 469 KEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKP-PKPPKPPRPPKTLKLKDGG 527
K P +P E P + K P T K P P+ +P P PK P P T +
Sbjct: 331 KSAPTTPKEPAP-------TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 383
Query: 528 KKKGKKSRESASPTIP 543
K + + +PT P
Sbjct: 384 TKSAPTTPKEPAPTTP 399
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 11/118 (9%)
Query: 458 SSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVK-MPKPSKIPKPPKPPKPPR 516
++ EV KE P+ I +P +S E +S + TPK ++ PK +P K P +
Sbjct: 812 TTSEVSTPTTTKE--PTTIHKSPDESTPE-LSAEPTPKALENSPKEPGVP-TTKTPAATK 867
Query: 517 PPKTLKLKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSV 574
P T KD ++ ++ + P + TKE T E + K T + V
Sbjct: 868 PEMTTTAKDKTTERDLRTTPETTTAAPKM------TKETATTTEKTTESKITATTTQV 919
Score = 33.1 bits (74), Expect = 1.5
Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 10/146 (6%)
Query: 942 SQQEEQKSKKKKSAKRKL--TPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTA 999
++ E + K K+ +R L TP TT+ + + TT+ TT + T +T ST+T
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT- 924
Query: 1000 SSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQ-AGRTSQPMAPGVFLTQRRPSAS 1058
+ ++P +++LA T T T + + + P T + +
Sbjct: 925 ------QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP 978
Query: 1059 SPNNNTAAKGKRTKKGMATAKQRLGK 1084
P T A K T R+ K
Sbjct: 979 KPQKPTKAPKKPTSTKKPKTMPRVRK 1004
Score = 32.7 bits (73), Expect = 1.9
Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 10/152 (6%)
Query: 905 SPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTT 964
+PT P+ +P + + T A + K+ K P TT
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 965 S-PSTSTSISAGTT------STSTTPASTTP---ASTTPASTSTASSQASQEGSSPEPPP 1014
P+ +T+ SA TT +T+ PA TTP A TTP + + + + EP P
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 1015 ESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
+ A T A T + + P
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 585
Score = 32.7 bits (73), Expect = 1.9
Identities = 40/182 (21%), Positives = 64/182 (35%), Gaps = 12/182 (6%)
Query: 884 EDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQ 943
E +P + AP +P + P+ P++ P A T A
Sbjct: 510 EPSPTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTP-KEPAPTTTKKPAPTTPKEP 567
Query: 944 QEEQKSKKKKSAKRKLTPNTT---SPSTSTSISAGTTS--TSTTPASTTPASTTPASTST 998
+ + +KLTP T +P+T + T TTP TP TTP +
Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP--TTPEEPAP 625
Query: 999 ASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSAS 1058
+ +A+ + EP P + A T A T + AP T + P+ +
Sbjct: 626 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP---TTLKEPAPT 682
Query: 1059 SP 1060
+P
Sbjct: 683 TP 684
Score = 32.3 bits (72), Expect = 2.5
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 9/95 (9%)
Query: 469 KEEPPSPIEATPPQSL--LEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDG 526
K P +P E P + K+ P T K P P+ P PK P P
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP------ 399
Query: 527 GKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEP 561
KK + + +PT P + A T EP
Sbjct: 400 -KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 433
Score = 32.0 bits (71), Expect = 3.3
Identities = 32/142 (22%), Positives = 47/142 (33%), Gaps = 8/142 (5%)
Query: 466 DREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKP-PKPPKPPRP----PKT 520
D+ P T P+ K+ P T K P+ + +P P PK P P P T
Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765
Query: 521 LK--LKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKME-PPKKGKATKSVLSVPNK 577
K K + + +PT P K A T E PP + +
Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 825
Query: 578 DVVHMQNDVERLEIREQTKSKS 599
+H D E+ + K+
Sbjct: 826 TTIHKSPDESTPELSAEPTPKA 847
Score = 31.2 bits (69), Expect = 5.6
Identities = 31/156 (19%), Positives = 50/156 (32%), Gaps = 6/156 (3%)
Query: 897 KGSDDAPYSP----TARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKK 952
K + P P T P+ P++ P + A K K
Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 561
Query: 953 KSAKRKL--TPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSP 1010
+ K TP T+P+T ++ T PA TTP + + + +
Sbjct: 562 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 621
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
EP P + ++ + A T A T + AP
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 59.3 bits (142), Expect = 2e-08
Identities = 55/190 (28%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 902 APYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTP 961
AP +P P+ P++ P + G A K E + KK A ++L P
Sbjct: 750 APTTPKG-TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK----EPAPTTPKKPAPKELAP 804
Query: 962 NTTSPSTSTSIS--AGTT------STSTTPASTT---PASTTPASTSTASSQASQEGSSP 1010
TT TST+ A TT +T PA TT PA TTP + +S+ S ++
Sbjct: 805 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 864
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR 1070
EP S + E +A T + + P PGV T + P+A+ P T AK K
Sbjct: 865 EPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGV-PTTKTPAATKPEMTTTAKDKT 919
Query: 1071 TKKGMATAKQ 1080
T++ + T +
Sbjct: 920 TERDLRTTPE 929
Score = 44.3 bits (103), Expect = 6e-04
Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 11/167 (6%)
Query: 883 DEDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLS 942
+E P + + AP +P P+ P++ P + G A K
Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-- 718
Query: 943 QQEEQKSKKKKSAKRKLTPNTTSPSTSTSIS--AGTTSTSTTPAS-TTPASTTPASTSTA 999
E + KK A ++L P TT TST+ A TT T P + PA TTP +
Sbjct: 719 --EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776
Query: 1000 SSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
+ + + + EP P + A T T TS AP
Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGPTSTTSDKPAP 820
Score = 38.5 bits (88), Expect = 0.035
Identities = 36/171 (21%), Positives = 63/171 (36%), Gaps = 17/171 (9%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P T P+ P++ P T A ++ + K+ + P+
Sbjct: 467 PAPTTKEPAPTTPKEPAP-----------TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS 515
Query: 963 TTSP---STSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSS 1019
T+P + +T+ SA TT+ P +T A TTP S +++ + EP P +
Sbjct: 516 PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 575
Query: 1020 SLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR 1070
A T A T++ AP T + P+ ++P K+
Sbjct: 576 PAPTTPKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKK 623
Score = 36.6 bits (83), Expect = 0.13
Identities = 25/97 (25%), Positives = 37/97 (38%), Gaps = 2/97 (2%)
Query: 468 EKEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKD 525
+K P +P E P P+ +K+ +P T K P P+ P K P P T
Sbjct: 488 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547
Query: 526 GGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPP 562
K+ + + +PT P K A T + P
Sbjct: 548 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584
Score = 36.2 bits (82), Expect = 0.17
Identities = 58/312 (18%), Positives = 108/312 (34%), Gaps = 26/312 (8%)
Query: 782 SSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKSA 841
S +PP T++ I+ S++ ++ + + S++ + KN + +
Sbjct: 136 SPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQ 195
Query: 842 GKRLLKRAAKNSVDLDDYEEEQ--DHLDACFKDSDY--VYPSLESDEDNPIFKSRSKKRK 897
K +K KN + D + + D+ P + + N + S K
Sbjct: 196 KKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKV----STSPK 251
Query: 898 GSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKR 957
+ P +P PS+P +E + + ET + + ++ K+K+
Sbjct: 252 ITTAKPINPR----PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 307
Query: 958 KLTPNTTSPSTSTSISAGTTSTSTTPASTT----PASTTPASTSTASSQASQEGSSPEPP 1013
K T + S TP + T PA TTP + + + + EP
Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 367
Query: 1014 PESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKR--- 1070
P + S+ + A T A T + AP T + P+ ++P K
Sbjct: 368 PTTIKSAPTTPKEPAPTTTKSAPT--TPKEPAP---TTTKEPAPTTPKEPAPTTTKEPAP 422
Query: 1071 --TKKGMATAKQ 1080
TK T K+
Sbjct: 423 TTTKSAPTTPKE 434
Score = 35.0 bits (79), Expect = 0.39
Identities = 37/178 (20%), Positives = 68/178 (38%), Gaps = 5/178 (2%)
Query: 893 SKKRKGSDDAPYSPTARVGPSVPRQD-RPVREGTRVASIETGLAAAAAKLSQQEEQKSKK 951
+ K+ +D + +A+ S+ + + + ++V + T A K K
Sbjct: 292 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 351
Query: 952 KKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPE 1011
+ K + P+ +T SA TT P +T A TTP + +++ + E
Sbjct: 352 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 411
Query: 1012 PPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGK 1069
P P + + A +A T A T + AP T + P+ ++P T K
Sbjct: 412 PAPTT-TKEPAPTTTKSAPTTPKEPAPTTPKKPAP---TTPKEPAPTTPKEPTPTTPK 465
Score = 35.0 bits (79), Expect = 0.39
Identities = 45/187 (24%), Positives = 64/187 (34%), Gaps = 25/187 (13%)
Query: 903 PYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
P T + P+ P++ P T A K K + K
Sbjct: 366 PTPTTIKSAPTTPKEPAPTT---------TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 416
Query: 963 TTSPSTSTSISAGTT------STSTTPASTTP---ASTTPASTSTASSQASQEGSSPEPP 1013
T P+ +T+ SA TT +T PA TTP A TTP T ++ ++ EP
Sbjct: 417 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAPTTKEPA 475
Query: 1014 PESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKK 1073
P + A T A T + AP T + PS ++P TK
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP---TTTKEPSPTTPKEPAPT---TTKS 529
Query: 1074 GMATAKQ 1080
T K+
Sbjct: 530 APTTTKE 536
Score = 35.0 bits (79), Expect = 0.39
Identities = 36/144 (25%), Positives = 50/144 (34%), Gaps = 12/144 (8%)
Query: 443 ENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKP 502
E A + T S + P P TP + K+ TP T K P P
Sbjct: 411 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPTPTTPKEPAP 469
Query: 503 S------KIPKPPKPPKPPRPPKTLKLKDG---GKKKGKKSRESASPTIPNLDLLEAHTK 553
+ PK P P P +P T + K+ + + SPT P + TK
Sbjct: 470 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK-EPAPTTTK 528
Query: 554 EALTKMEPPKKGKATKSVLSVPNK 577
A T + P TKS + P +
Sbjct: 529 SAPTTTKEPAP-TTTKSAPTTPKE 551
Score = 35.0 bits (79), Expect = 0.39
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 4/103 (3%)
Query: 906 PTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKL---TPN 962
PT + + P++ T A+ A K ++++ + + + +A K+ T
Sbjct: 884 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT 943
Query: 963 TTSPSTSTSISAGTTS-TSTTPASTTPASTTPASTSTASSQAS 1004
TT +T + I+A TT TSTT TTP T T+T + + +
Sbjct: 944 TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 986
Score = 34.7 bits (78), Expect = 0.51
Identities = 34/141 (24%), Positives = 46/141 (32%), Gaps = 31/141 (21%)
Query: 434 DLAKEIRLSENASKAVRPEVNTVASSDEVCDGDRE--KEEPPSPIEATPPQSLL--EKVS 489
D +KE L+ N V + T + DG + + IE T + L KV
Sbjct: 269 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 328
Query: 490 KKKTPK---------------------------TVKMPKPSKIPKPPKPPKPPRPPKTLK 522
K TPK T K P P+ I P PK P P T
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 388
Query: 523 LKDGGKKKGKKSRESASPTIP 543
K+ + + +PT P
Sbjct: 389 APTTPKEPAPTTTKEPAPTTP 409
Score = 34.7 bits (78), Expect = 0.51
Identities = 32/117 (27%), Positives = 44/117 (37%), Gaps = 14/117 (11%)
Query: 469 KEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP---------PKPPKPPRP 517
KE P+ ++ P P+ +K+ P T K P P+ KP P PK P P
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 518 PKTLK-LKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLS 573
T K K+ + + +PT P L T E L P K T L+
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKETAPTTPK--KLTPTTPEKLAPTTPEKPAPTTPEELA 649
Score = 34.7 bits (78), Expect = 0.51
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 8/97 (8%)
Query: 472 PPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP----PKPPKPPRPPKTLKLKD 525
P +P E P P+ K+ P T K P P+ KP PK P P P +T
Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621
Query: 526 GGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPP 562
KK + E +PT P + A T E P
Sbjct: 622 --KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656
Score = 33.9 bits (76), Expect = 0.87
Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 8/95 (8%)
Query: 451 PEVNTVASSDEVCDGDREKEEPPSPIEATP--PQSLLEKVSKKKTPKTVKMPKPSKIPKP 508
PE + +E+ E+ P +P E P P++ K+ P T K P P+
Sbjct: 637 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT----T 692
Query: 509 PKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTIP 543
PK P P P +T G + + +PT P
Sbjct: 693 PKEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTP 725
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 469 KEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKP-PKPPKPPRPPKTLKLKDGG 527
K P +P E P + K P T K P P+ +P P PK P P T +
Sbjct: 372 KSAPTTPKEPAP-------TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 424
Query: 528 KKKGKKSRESASPTIP 543
K + + +PT P
Sbjct: 425 TKSAPTTPKEPAPTTP 440
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 11/118 (9%)
Query: 458 SSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVK-MPKPSKIPKPPKPPKPPR 516
++ EV KE P+ I +P +S E +S + TPK ++ PK +P K P +
Sbjct: 853 TTSEVSTPTTTKE--PTTIHKSPDESTPE-LSAEPTPKALENSPKEPGVP-TTKTPAATK 908
Query: 517 PPKTLKLKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSV 574
P T KD ++ ++ + P + TKE T E + K T + V
Sbjct: 909 PEMTTTAKDKTTERDLRTTPETTTAAPKM------TKETATTTEKTTESKITATTTQV 960
Score = 33.1 bits (74), Expect = 1.5
Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 10/146 (6%)
Query: 942 SQQEEQKSKKKKSAKRKL--TPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTA 999
++ E + K K+ +R L TP TT+ + + TT+ TT + T +T ST+T
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT- 965
Query: 1000 SSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQ-AGRTSQPMAPGVFLTQRRPSAS 1058
+ ++P +++LA T T T + + + P T + +
Sbjct: 966 ------QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP 1019
Query: 1059 SPNNNTAAKGKRTKKGMATAKQRLGK 1084
P T A K T R+ K
Sbjct: 1020 KPQKPTKAPKKPTSTKKPKTMPRVRK 1045
Score = 32.7 bits (73), Expect = 1.9
Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 10/152 (6%)
Query: 905 SPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTT 964
+PT P+ +P + + T A + K+ K P TT
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 965 S-PSTSTSISAGTT------STSTTPASTTP---ASTTPASTSTASSQASQEGSSPEPPP 1014
P+ +T+ SA TT +T+ PA TTP A TTP + + + + EP P
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 1015 ESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
+ A T A T + + P
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 626
Score = 32.7 bits (73), Expect = 1.9
Identities = 40/182 (21%), Positives = 64/182 (35%), Gaps = 12/182 (6%)
Query: 884 EDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQ 943
E +P + AP +P + P+ P++ P A T A
Sbjct: 551 EPSPTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTP-KEPAPTTTKKPAPTTPKEP 608
Query: 944 QEEQKSKKKKSAKRKLTPNTT---SPSTSTSISAGTTS--TSTTPASTTPASTTPASTST 998
+ + +KLTP T +P+T + T TTP TP TTP +
Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP--TTPEEPAP 666
Query: 999 ASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSAS 1058
+ +A+ + EP P + A T A T + AP T + P+ +
Sbjct: 667 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP---TTLKEPAPT 723
Query: 1059 SP 1060
+P
Sbjct: 724 TP 725
Score = 32.3 bits (72), Expect = 2.5
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 9/95 (9%)
Query: 469 KEEPPSPIEATPPQSL--LEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDG 526
K P +P E P + K+ P T K P P+ P PK P P
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP------ 440
Query: 527 GKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEP 561
KK + + +PT P + A T EP
Sbjct: 441 -KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 474
Score = 32.0 bits (71), Expect = 3.3
Identities = 32/142 (22%), Positives = 47/142 (33%), Gaps = 8/142 (5%)
Query: 466 DREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKP-PKPPKPPRP----PKT 520
D+ P T P+ K+ P T K P+ + +P P PK P P P T
Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806
Query: 521 LK--LKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKME-PPKKGKATKSVLSVPNK 577
K K + + +PT P K A T E PP + +
Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 866
Query: 578 DVVHMQNDVERLEIREQTKSKS 599
+H D E+ + K+
Sbjct: 867 TTIHKSPDESTPELSAEPTPKA 888
Score = 31.2 bits (69), Expect = 5.6
Identities = 31/156 (19%), Positives = 50/156 (32%), Gaps = 6/156 (3%)
Query: 897 KGSDDAPYSP----TARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKK 952
K + P P T P+ P++ P + A K K
Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 602
Query: 953 KSAKRKL--TPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSP 1010
+ K TP T+P+T ++ T PA TTP + + + +
Sbjct: 603 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 662
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAP 1046
EP P + ++ + A T A T + AP
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 57.8 bits (138), Expect = 6e-08
Identities = 82/351 (23%), Positives = 135/351 (38%), Gaps = 45/351 (12%)
Query: 524 KDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQ 583
K+ GK+K K+ +E T P +L KE + P K KA ++ P +
Sbjct: 1271 KEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKERTP-------K 1323
Query: 584 NDVERLEIREQTKSKSEAKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKK 643
+D E+ + +++ K+K E K+K + P++ K +E++ EK P +++ + +K+
Sbjct: 1324 SDKEKEKFKKEEKAKDE---KFKTTVPNAESKSTQEREREKEP---SRERDIAKEMKSKE 1377
Query: 644 LLGSKALRPPTSPGVFGALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRD 703
+ P V G+L++ P P D E + KID P + K
Sbjct: 1378 NVKGGEKTP-----VSGSLKS-----PVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDS 1427
Query: 704 LSFLLDKKAVL-----PTPVTKPKLDSAAYKSDDSSDEGSLHIDTDTKPGRNARVKKESG 758
L L + A L P P++K K K D S E S + + R R + S
Sbjct: 1428 LIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDHSN 1487
Query: 759 SSAAGILDLLQASEEVG---ALEYNPSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTW 815
+ DL + +E + + S P SP E D +
Sbjct: 1488 NDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNE-------------KDKEKNKSK 1534
Query: 816 GAGQAKGS-SLAAHGARKNGGGSGKSAGKRLLKRAAKNSVDLDDYEEEQDH 865
+G+ KGS S + K G K + K K D +EE+ H
Sbjct: 1535 SSGKEKGSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKH 1585
Score = 42.7 bits (99), Expect = 0.002
Identities = 77/332 (23%), Positives = 141/332 (42%), Gaps = 49/332 (14%)
Query: 444 NASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPS 503
N++KAV+ +D+ ++EKE+ TP +L K K+K K +P+
Sbjct: 1261 NSNKAVK-------ENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKP----KEERPN 1309
Query: 504 KIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPK 563
K K + + R PK+ K K+ KK+ K E T+PN + T+E + EP +
Sbjct: 1310 KDEKARETKE--RTPKSDKEKEKFKKEEKAKDEKFKTTVPNAE--SKSTQEREREKEPSR 1365
Query: 564 KGKATKSVLSVPN-----KDVV--HMQNDVERLEI----REQTKSK--SEAKWKYKNSKP 610
+ K + S N K V +++ V R +I REQ + K + + ++
Sbjct: 1366 ERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVK 1425
Query: 611 DSLLKMEEEQ-KL----EKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTSPGVFGALQNF 665
DSL++++E KL PL+ +K+ + +KK L R + +
Sbjct: 1426 DSLIELKESSAKLYINHTPPPLSKSKEREM-----DKKDLDKSRER---------SRERE 1471
Query: 666 KEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLPTPVTKPKLDS 725
K+D+ + ++ ++D E+ D R+++N + P P K K +
Sbjct: 1472 KKDEKDRKERKRDHSNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKN 1531
Query: 726 AAYKSDDSSDEGSLHIDTDTKPGRNARVKKES 757
+ S ++GS ++ ++ KKES
Sbjct: 1532 KSKSS--GKEKGSDSFKSEKMDKISSGGKKES 1561
Score = 32.3 bits (72), Expect = 2.5
Identities = 39/166 (23%), Positives = 65/166 (39%), Gaps = 32/166 (19%)
Query: 884 EDNPIFKSRSKKRKGSDDAPYS-PTARV----GPSVPRQDRPVREGTRVASIETGLAAAA 938
++N K + K+++ + P + P ARV G P+++RP ++ + E
Sbjct: 1267 KENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKER------ 1320
Query: 939 AKLSQQEEQKSKKKKSAK----RKLTPNTTS-----------PSTSTSISAGTTSTST-- 981
S +E++K KK++ AK + PN S PS I+ S
Sbjct: 1321 TPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENVK 1380
Query: 982 ----TPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLAD 1023
TP S + S P S + + P SHSS++ D
Sbjct: 1381 GGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSSTVKD 1426
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 57.8 bits (138), Expect = 6e-08
Identities = 82/352 (23%), Positives = 136/352 (38%), Gaps = 36/352 (10%)
Query: 664 NFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLPTPVTKPKL 723
N +D+P E ++ DG ++ ++ + +D F DK + P KP++
Sbjct: 100 NITKDEPVCAIKNEEEMAPDG---CEDIVVKSFSESQNKDEEFEKDKIKMKP----KPRI 152
Query: 724 DSAAYKSDDSSDEGSLHIDTDTKPG---RNARVKKESGSSAAGILDLLQASEEVGALEYN 780
S KS S++ SL D KP R+ KK G+ D A E L
Sbjct: 153 LSI--KSTSSAENNSLDTDDHFKPSPRPRSMLKKKSHMEEKDGLEDKETALSEELELHSA 210
Query: 781 PSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKS 840
PSS P + EA + S NL DSCL + A S G + G G +
Sbjct: 211 PSSLPTPNGIQLEAEKKAFS-ENLDPEDSCLTSL-----ASSSLKQILGDSFSPGSEGNA 264
Query: 841 AGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDNPIFKSRSKKRKGSD 900
+GK + +N L E +++ A D+V ++E +++ + ++ K
Sbjct: 265 SGKDPNEEITENHNSLKSDENKENSFSA-----DHVTTAVEKSKESQVTADDLEEEKAKA 319
Query: 901 DAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLT 960
+ V P + + SI +A A+ E++ K KKS + +
Sbjct: 320 ELIMDDDRTVDPLLSKSQ----------SILISTSATASSKKTIEDRNIKNKKSTNNRAS 369
Query: 961 PNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEP 1012
+ TS + ++S TP++TT S+ T Q + S EP
Sbjct: 370 SASARLMTSEFLKK-SSSKRRTPSTTT--SSHYLGTLKVLDQKPSQKQSIEP 418
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 56.6 bits (135), Expect = 1e-07
Identities = 66/295 (22%), Positives = 122/295 (41%), Gaps = 35/295 (11%)
Query: 407 RSWTKKQALAEHEDELPEHFKPSQLIKDLAKEIRLSENASKAVR-----PEVNTVASSDE 461
+S K ++ + E + PE K +K+ AK +++ KA PE T A +
Sbjct: 717 KSPEKAKSPVKEEAKTPE--KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 462 VCDGDREKEEPPSPI----------------EATPPQSLLEKVSKKKTP-KTVKMPKPSK 504
D+ E+ SP+ +A P+ + K + K+P K + P+ K
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK 834
Query: 505 IPKPPK---PPKPPRPPKTLKLKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEP 561
+ +PPK K P PKT + KD K++ K +E+ P + A K +K+E
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK-KEAPKPKVEE-KKEPAVEKPKESKVEA 892
Query: 562 PKKGKATKSVLSVPNKDV---VHMQNDV---ERLEIREQTKSKSEAKWKYKNSKPDSLLK 615
K+ K + P K+ V ++ D E+ E+ ++ ++AK K ++
Sbjct: 893 KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAP 952
Query: 616 MEEEQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTSPGVFGALQNFKEDKP 670
+++ K EK+ K + + + K L + +P + + K+ KP
Sbjct: 953 EKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007
Score = 54.7 bits (130), Expect = 5e-07
Identities = 114/601 (18%), Positives = 221/601 (36%), Gaps = 66/601 (10%)
Query: 424 EHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQS 483
E + +Q+ +++ +E E +K + +E G+ E + PP+ A+P +
Sbjct: 459 EQTEETQVTEEVTEE---EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKE 515
Query: 484 LLEKVSKK-KTPKTVKMPK------PSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRE 536
V ++ K+P K P+ P+++ P K P + + K + K + E
Sbjct: 516 AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE----EAKSPPEAKSPEKEE 571
Query: 537 SASPT-IPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIREQT 595
+ SP + + + ++ KE K + KS + K ++ V +E+
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPV-----KEEA 626
Query: 596 KSKSEAKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTS 655
KS +E K K P EE + EK+ ++ K K + ++A P +
Sbjct: 627 KSPAEVKSPEKAKSPTK----EEAKSPEKAKSPEKEEAK--SPEKAKSPVKAEAKSPEKA 680
Query: 656 PGVFGALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLP 715
A E PV++E + + + P++ + +P++ S + ++A P
Sbjct: 681 KSPVKAEAKSPEKAKSPVKEEAK------SPEKAKSPVKEEAKSPEKAKS-PVKEEAKTP 733
Query: 716 TPVTKPKLDSAAYKSDDSSDEGSLHIDTDTKPGRNARVKKESGSSAAGILDLLQASEEVG 775
P + A S E + +D + P K+E+ S A D +
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKS-PEAKTPAKEEARSPA----DKFPEKAKSP 788
Query: 776 ALEYNPSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGG 835
E S + SP ++A + + S ++ + K +
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAP 848
Query: 836 GSGKSAGKRLLKR--AAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDNPIFKSRS 893
+ K+ K+ K+ A K EE+++ P++E +++ K +
Sbjct: 849 ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE-------------PAVEKPKES---KVEA 892
Query: 894 KKRKGSDDAPYSPTARVGPS--VPRQDRPVREGTRVASIETGLAAA--AAKLSQQEEQKS 949
KK + D + P+ ++D +E T VA E A A +K ++++E
Sbjct: 893 KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAP 952
Query: 950 KKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSS 1009
+KK + + K P T + S P S A + SS Q+ S
Sbjct: 953 EKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP------SKPKAEKAEKSSSTDQKDSK 1006
Query: 1010 P 1010
P
Sbjct: 1007 P 1007
Score = 45.8 bits (107), Expect = 2e-04
Identities = 74/332 (22%), Positives = 123/332 (37%), Gaps = 57/332 (17%)
Query: 407 RSWTKKQALAEHEDELPEHFKPSQLIKDLAKEIRLSENASK--AVRPEVNTVASSDEVCD 464
+S K ++ + E + PE K +K+ AK +++ K A PE + D
Sbjct: 703 KSPEKAKSPVKEEAKSPE--KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD 760
Query: 465 GDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLK 524
+ + P+ EA P + +K + VK P+ +K P P
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP---------- 810
Query: 525 DGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQN 584
+K+ K E SP + E + + EPPKK + K+ + +
Sbjct: 811 ---EKEIPKKEEVKSP------VKEEEKPQEVKVKEPPKKAEEEKAPATPKTE------- 854
Query: 585 DVERLEIREQTKSKSEAKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKL 644
E+ + +++ K EA K + ++ +E K+E KK
Sbjct: 855 --EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEA-----------------KKE 895
Query: 645 LGSKALRPPTSPGVFGALQNFKED-KPKPVRDEYEYVSDDGELKIDEFPIRRKKNAP-KR 702
+ PT A KED KPK + + DD + K P +K+ AP K+
Sbjct: 896 EAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKK 955
Query: 703 DLSFLLDKKAVLPTPVTKPKLDSAAYKSDDSS 734
D K+ P KPK ++ A K DD +
Sbjct: 956 D-----TKEEKAKKPEEKPKTEAKA-KEDDKT 981
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 55.1 bits (131), Expect = 4e-07
Identities = 147/701 (20%), Positives = 247/701 (35%), Gaps = 102/701 (14%)
Query: 446 SKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKI 505
+KA +PE ++ +SS+E D E+E P + ++LL+ + KT + P+K
Sbjct: 253 TKAGKPEEDSESSSEE--SSDSEEETPAA-------KALLQAKASGKTSQVGAASAPAK- 302
Query: 506 PKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEP---- 561
+ P+ P PP + GK+ +S S + + EA + + P
Sbjct: 303 -ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 361
Query: 562 ---PKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKSKSEAKWKYKNSKPDSLLKMEE 618
P K K P + V+ + E ++S SE +S ++L M
Sbjct: 362 ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEE----SDSDREALAAMNA 417
Query: 619 EQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTSPGVFG----ALQNFKEDKPKPVR 674
Q PL G S LG A P PG G + Q K ++
Sbjct: 418 AQ---VKPL-GKSPQVKPASTMGMGPLGKGA--GPVPPGKVGPATPSAQVGKWEEDSESS 471
Query: 675 DEYEYVSDDGELKIDEFPIRRK---------------KNAPKRDLSFLLDKKAVLPTPVT 719
E S DGE+ P + K K P++ + KA P +
Sbjct: 472 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 531
Query: 720 KPKLDSAAYKSDDSSDEGSLHIDTDTKPG-----RNARVKKESGSSAAGILDL---LQAS 771
+ +S+ S DS + + KP A KK + +++A + + QA
Sbjct: 532 ESSEESS--DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 589
Query: 772 EEVGALEYNPSSQPPASPSTQEAIQGMLSM--ANLQASDSCLQTTWGAGQAKGSSLAAHG 829
+ G S P + TQ + S ++ + + L T G ++ G L
Sbjct: 590 RKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKA 649
Query: 830 AR---KNGGGSGKS------AGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSL 880
A K G G + G + + A+ D + EEE D +A +
Sbjct: 650 ASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVK 709
Query: 881 ESDEDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLA----- 935
++ +R+ KG+ AP + R V+ R T LA
Sbjct: 710 KTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPAS 769
Query: 936 ----------AAAAKLSQQEEQKSKKKK--SAKRKLTPNTTSPSTST-SISAGTTSTSTT 982
AA A+ +E+ S +++ S + T PS T I A +
Sbjct: 770 VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKES 829
Query: 983 PASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQ 1042
P A T P T +++QA ++ S SS +D + A T AQ +
Sbjct: 830 PRKGA-APTPPGKTGPSAAQAGKQDDS------GSSSEESDSDGEAPAAVTSAQVIK--- 879
Query: 1043 PMAPGVFLTQRR----PSASSPNNNTAAKGKRTKKGMATAK 1079
P +F+ R P+A+ A+ ++ + +TA+
Sbjct: 880 --PPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTAR 918
Score = 45.4 bits (106), Expect = 3e-04
Identities = 95/425 (22%), Positives = 148/425 (34%), Gaps = 43/425 (10%)
Query: 653 PTSPGVFGALQN-FKEDKPKPVRDEYEYVSDDGELKIDEFPIRRK--------------- 696
P PG GA+ + K KP+ + S D E +E P +
Sbjct: 240 PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE---EETPAAKALLQAKASGKTSQVGA 296
Query: 697 KNAPKRDLSFLLDKKAVLPTPVTK--PKLDSA-AYKSDDSSDEGSLHIDTDTKPGRNARV 753
+AP ++ +K P P K P + A A K ++ S S D++ + A+
Sbjct: 297 ASAPAKESP----RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 352
Query: 754 KKESGSSAAGILDLLQASEEVGALEYNPSSQPPASPSTQEAIQGMLSMANLQASDSCLQT 813
++ A ++ + GA P PA+ Q Q S ++ + SDS +
Sbjct: 353 SGKAPQVRAASAPAKESPRK-GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 411
Query: 814 --TWGAGQAK--GSSLAAHGARKNGGGS-GKSAGKRLLKRA--AKNSVDLDDYEEEQDHL 866
A Q K G S A G G GK AG + A S + +EE+ +
Sbjct: 412 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 471
Query: 867 DACFKDSD------YVYPSLESDEDNPI-FKSRSKKRKGSDDAPYSPTARVGPSVPRQDR 919
DS V P+ E N + K S KG +V P +
Sbjct: 472 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 531
Query: 920 PVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTTSPSTSTSISAGTTST 979
E + ++ AA + K + K+ +K NTT+ + + GT +
Sbjct: 532 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAP 589
Query: 980 STTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGR 1039
+T+PA ++PA A SS E E + LA A G Q
Sbjct: 590 RKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKA 649
Query: 1040 TSQPM 1044
S P+
Sbjct: 650 ASVPV 654
Score = 38.5 bits (88), Expect = 0.035
Identities = 80/366 (21%), Positives = 131/366 (35%), Gaps = 45/366 (12%)
Query: 740 HIDTDTKPGRNARVKKESGSSA-----AGILDLLQASEEVGALEYNPSSQPPASPSTQEA 794
H ++ GR + ++++ A + + ++SEE E + P ST +
Sbjct: 52 HWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSS 111
Query: 795 IQGMLSMANLQAS--DSCLQTTWGAGQAKGSSLAAHGARKNGGG--SGKSAGKRLLKRAA 850
+ G A+L +S + T AG+ G+S+ K SGKS K A
Sbjct: 112 VLG----ADLPSSMKEKAKAETEKAGKT-GNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
Query: 851 KNSVDLDDYEEEQDHLDACFK---------DSDYVYPSLESDEDNPIFKSRSK---KRKG 898
V + E A K DS S SDE + K+ K R
Sbjct: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAA 226
Query: 899 SDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRK 958
S A +P P+ P + V T+ E +++ + S EE+ K + K
Sbjct: 227 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAK 286
Query: 959 LTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHS 1018
+ T+ +++ + + PA P T PA + + ++ S S
Sbjct: 287 ASGKTSQVGAASAPAKESPRKGAAPA--PPGKTGPAVAKAQAGKREEDSQS--------S 336
Query: 1019 SSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKKGMATA 1078
S +D E A +G+ Q A P+ SP A R K G A A
Sbjct: 337 SEESDSEEEAPA--QAKPSGKAPQVRAASA------PAKESPRKGAAPAPPR-KTGPAAA 387
Query: 1079 KQRLGK 1084
+ ++GK
Sbjct: 388 QVQVGK 393
Score = 32.0 bits (71), Expect = 3.3
Identities = 40/194 (20%), Positives = 77/194 (39%), Gaps = 19/194 (9%)
Query: 715 PTPVTKPKLDSAAYK--SDDSSDEGSLHIDT---DTKPGRNARVKKESGSSAAGILDLLQ 769
P P+ + ++ ++ K ++ E +DT ++ G +R +K SG A +
Sbjct: 1227 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1286
Query: 770 ASEEVGALEYNPSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGS---SLA 826
+++GA E +S P ST + A+ + + + G+ AK L
Sbjct: 1287 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ 1346
Query: 827 AHGARKNGGGSGKSAGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDN 886
GG K+ K++ K D + E+++ A KDS ++
Sbjct: 1347 KGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS-----------ES 1395
Query: 887 PIFKSRSKKRKGSD 900
P K + KK+K ++
Sbjct: 1396 PSQKKKKKKKKTAE 1409
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 55.1 bits (131), Expect = 4e-07
Identities = 147/701 (20%), Positives = 247/701 (35%), Gaps = 102/701 (14%)
Query: 446 SKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKPSKI 505
+KA +PE ++ +SS+E D E+E P + ++LL+ + KT + P+K
Sbjct: 253 TKAGKPEEDSESSSEE--SSDSEEETPAA-------KALLQAKASGKTSQVGAASAPAK- 302
Query: 506 PKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTIPNLDLLEAHTKEALTKMEP---- 561
+ P+ P PP + GK+ +S S + + EA + + P
Sbjct: 303 -ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 361
Query: 562 ---PKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKSKSEAKWKYKNSKPDSLLKMEE 618
P K K P + V+ + E ++S SE +S ++L M
Sbjct: 362 ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEE----SDSDREALAAMNA 417
Query: 619 EQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPPTSPGVFG----ALQNFKEDKPKPVR 674
Q PL G S LG A P PG G + Q K ++
Sbjct: 418 AQ---VKPL-GKSPQVKPASTMGMGPLGKGA--GPVPPGKVGPATPSAQVGKWEEDSESS 471
Query: 675 DEYEYVSDDGELKIDEFPIRRK---------------KNAPKRDLSFLLDKKAVLPTPVT 719
E S DGE+ P + K K P++ + KA P +
Sbjct: 472 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 531
Query: 720 KPKLDSAAYKSDDSSDEGSLHIDTDTKPG-----RNARVKKESGSSAAGILDL---LQAS 771
+ +S+ S DS + + KP A KK + +++A + + QA
Sbjct: 532 ESSEESS--DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 589
Query: 772 EEVGALEYNPSSQPPASPSTQEAIQGMLSM--ANLQASDSCLQTTWGAGQAKGSSLAAHG 829
+ G S P + TQ + S ++ + + L T G ++ G L
Sbjct: 590 RKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKA 649
Query: 830 AR---KNGGGSGKS------AGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSL 880
A K G G + G + + A+ D + EEE D +A +
Sbjct: 650 ASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVK 709
Query: 881 ESDEDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLA----- 935
++ +R+ KG+ AP + R V+ R T LA
Sbjct: 710 KTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPAS 769
Query: 936 ----------AAAAKLSQQEEQKSKKKK--SAKRKLTPNTTSPSTST-SISAGTTSTSTT 982
AA A+ +E+ S +++ S + T PS T I A +
Sbjct: 770 VPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKES 829
Query: 983 PASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQ 1042
P A T P T +++QA ++ S SS +D + A T AQ +
Sbjct: 830 PRKGA-APTPPGKTGPSAAQAGKQDDS------GSSSEESDSDGEAPAAVTSAQVIK--- 879
Query: 1043 PMAPGVFLTQRR----PSASSPNNNTAAKGKRTKKGMATAK 1079
P +F+ R P+A+ A+ ++ + +TA+
Sbjct: 880 --PPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTAR 918
Score = 45.4 bits (106), Expect = 3e-04
Identities = 95/425 (22%), Positives = 148/425 (34%), Gaps = 43/425 (10%)
Query: 653 PTSPGVFGALQN-FKEDKPKPVRDEYEYVSDDGELKIDEFPIRRK--------------- 696
P PG GA+ + K KP+ + S D E +E P +
Sbjct: 240 PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE---EETPAAKALLQAKASGKTSQVGA 296
Query: 697 KNAPKRDLSFLLDKKAVLPTPVTK--PKLDSA-AYKSDDSSDEGSLHIDTDTKPGRNARV 753
+AP ++ +K P P K P + A A K ++ S S D++ + A+
Sbjct: 297 ASAPAKESP----RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 352
Query: 754 KKESGSSAAGILDLLQASEEVGALEYNPSSQPPASPSTQEAIQGMLSMANLQASDSCLQT 813
++ A ++ + GA P PA+ Q Q S ++ + SDS +
Sbjct: 353 SGKAPQVRAASAPAKESPRK-GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 411
Query: 814 --TWGAGQAK--GSSLAAHGARKNGGGS-GKSAGKRLLKRA--AKNSVDLDDYEEEQDHL 866
A Q K G S A G G GK AG + A S + +EE+ +
Sbjct: 412 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 471
Query: 867 DACFKDSD------YVYPSLESDEDNPI-FKSRSKKRKGSDDAPYSPTARVGPSVPRQDR 919
DS V P+ E N + K S KG +V P +
Sbjct: 472 SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS 531
Query: 920 PVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTTSPSTSTSISAGTTST 979
E + ++ AA + K + K+ +K NTT+ + + GT +
Sbjct: 532 ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT--NTTASAKVAPVRVGTQAP 589
Query: 980 STTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGR 1039
+T+PA ++PA A SS E E + LA A G Q
Sbjct: 590 RKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKA 649
Query: 1040 TSQPM 1044
S P+
Sbjct: 650 ASVPV 654
Score = 38.5 bits (88), Expect = 0.035
Identities = 80/366 (21%), Positives = 131/366 (35%), Gaps = 45/366 (12%)
Query: 740 HIDTDTKPGRNARVKKESGSSA-----AGILDLLQASEEVGALEYNPSSQPPASPSTQEA 794
H ++ GR + ++++ A + + ++SEE E + P ST +
Sbjct: 52 HWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSS 111
Query: 795 IQGMLSMANLQAS--DSCLQTTWGAGQAKGSSLAAHGARKNGGG--SGKSAGKRLLKRAA 850
+ G A+L +S + T AG+ G+S+ K SGKS K A
Sbjct: 112 VLG----ADLPSSMKEKAKAETEKAGKT-GNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
Query: 851 KNSVDLDDYEEEQDHLDACFK---------DSDYVYPSLESDEDNPIFKSRSK---KRKG 898
V + E A K DS S SDE + K+ K R
Sbjct: 167 TTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAA 226
Query: 899 SDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRK 958
S A +P P+ P + V T+ E +++ + S EE+ K + K
Sbjct: 227 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAK 286
Query: 959 LTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHS 1018
+ T+ +++ + + PA P T PA + + ++ S S
Sbjct: 287 ASGKTSQVGAASAPAKESPRKGAAPA--PPGKTGPAVAKAQAGKREEDSQS--------S 336
Query: 1019 SSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKKGMATA 1078
S +D E A +G+ Q A P+ SP A R K G A A
Sbjct: 337 SEESDSEEEAPA--QAKPSGKAPQVRAASA------PAKESPRKGAAPAPPR-KTGPAAA 387
Query: 1079 KQRLGK 1084
+ ++GK
Sbjct: 388 QVQVGK 393
Score = 32.0 bits (71), Expect = 3.3
Identities = 40/194 (20%), Positives = 77/194 (39%), Gaps = 19/194 (9%)
Query: 715 PTPVTKPKLDSAAYK--SDDSSDEGSLHIDT---DTKPGRNARVKKESGSSAAGILDLLQ 769
P P+ + ++ ++ K ++ E +DT ++ G +R +K SG A +
Sbjct: 1226 PWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSK 1285
Query: 770 ASEEVGALEYNPSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQAKGS---SLA 826
+++GA E +S P ST + A+ + + + G+ AK L
Sbjct: 1286 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ 1345
Query: 827 AHGARKNGGGSGKSAGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDN 886
GG K+ K++ K D + E+++ A KDS ++
Sbjct: 1346 KGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS-----------ES 1394
Query: 887 PIFKSRSKKRKGSD 900
P K + KK+K ++
Sbjct: 1395 PSQKKKKKKKKTAE 1408
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 55.1 bits (131), Expect = 4e-07
Identities = 37/120 (30%), Positives = 66/120 (55%), Gaps = 8/120 (6%)
Query: 954 SAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPP 1013
++ R +P ++S S+S+S S+ ++S+S++ +S++ +S++ +S+S++SS +S SS
Sbjct: 2605 ASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2664
Query: 1014 PESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQR-------RPSASSPNNNTAA 1066
S SSS D + + + A A T+ P A T+ RPSA SP T A
Sbjct: 2665 SSSSSSSTTDEDSSCSSDDEAAPAP-TAGPSAQAALPTKATKQAGKARPSAHSPGKKTPA 2723
Score = 37.7 bits (86), Expect = 0.060
Identities = 28/108 (25%), Positives = 40/108 (37%), Gaps = 6/108 (5%)
Query: 442 SENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQSLLE----KVSKKKTPKTV 497
S ++S + ++ D C D E P+P Q+ L K + K P
Sbjct: 2658 SSSSSSSSSSSSSSTTDEDSSCSSD--DEAAPAPTAGPSAQAALPTKATKQAGKARPSAH 2715
Query: 498 KMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESASPTIPNL 545
K + P+P PP P P K + G K + KK PT L
Sbjct: 2716 SPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKEL 2763
Score = 35.8 bits (81), Expect = 0.23
Identities = 27/167 (16%), Positives = 68/167 (40%)
Query: 912 PSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTTSPSTSTS 971
P P + + ++G + + ++ ++ S + + + T
Sbjct: 2541 PKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
Query: 972 ISAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAGT 1031
+ +S + +PAS++ +S++ +S+S++SS +S SS S SSS + +++ +
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660
Query: 1032 FTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKKGMATA 1078
+ + + +S + +A +P +A+ K A
Sbjct: 2661 SSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQA 2707
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 18/134 (13%)
Query: 428 PSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPI---------EA 478
P +L + L+ + S+ + A++P V T+ C+G P+ + EA
Sbjct: 255 PPRLAERLSPFLAESKTKNAALQPSVLTM------CNGGAGDVGLPALVAEAGRGGAKEA 308
Query: 479 TPPQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPK-PPRPPKTLK--LKDGGKKKGKKSR 535
+ + +T P PS +P PP PPK PP PP + +++G++ R
Sbjct: 309 ARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHR 368
Query: 536 ESASPTIPNLDLLE 549
A +P+++ +
Sbjct: 369 VVAPTFVPSVEAFD 382
Score = 31.2 bits (69), Expect = 5.6
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 11/79 (13%)
Query: 472 PPSPIEATPPQSLLEKVSKK-----KTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDG 526
PPSP A+P +L KV +K K P PS P P P PP P + ++
Sbjct: 993 PPSP-RASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEA 1051
Query: 527 -----GKKKGKKSRESASP 540
KK + +E+ SP
Sbjct: 1052 PENVVEKKDLELEKEAPSP 1070
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 54.7 bits (130), Expect = 5e-07
Identities = 40/126 (31%), Positives = 63/126 (50%), Gaps = 4/126 (3%)
Query: 944 QEEQKSKKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTP-ASTTPASTTPASTSTASSQ 1002
Q +K ++ T T++P TST+ A TTST++ P A TT A TT ++++ +S
Sbjct: 1869 QSTSSWQKSRTTTLVTTSTTSTPQTSTTY-AHTTSTTSAPTARTTSAPTTRTTSASPAST 1927
Query: 1003 ASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSA--SSP 1060
S G++P P P + + S T+A T + A +S AP T S+ SSP
Sbjct: 1928 TSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSP 1987
Query: 1061 NNNTAA 1066
+T +
Sbjct: 1988 QTSTTS 1993
Score = 44.3 bits (103), Expect = 6e-04
Identities = 24/56 (42%), Positives = 36/56 (64%), Gaps = 1/56 (1%)
Query: 960 TPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTST-ASSQASQEGSSPEPPP 1014
T +TTS TS++ SA TTST++ P S+T +S ++TS +S S G++P P P
Sbjct: 1956 TTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVP 2011
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/110 (31%), Positives = 51/110 (46%), Gaps = 9/110 (8%)
Query: 960 TPNTTSPSTSTSISAGTT-STSTTPASTT--------PASTTPASTSTASSQASQEGSSP 1010
T +TTS T+ + SA TT +TS +PASTT P TT ++ +S S +S
Sbjct: 1900 TTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTST 1959
Query: 1011 EPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSP 1060
P S ++S T+A T + + +TS AP T + SP
Sbjct: 1960 TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSP 2009
Score = 41.2 bits (95), Expect = 0.005
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 6/92 (6%)
Query: 954 SAKRKLTPNTTSPSTSTSISAGTTSTSTTP--ASTTPASTTPASTSTASSQASQEGSSPE 1011
S+ + TP TTS +T T S G+++ S+TP S + A TTPA + S + + SP
Sbjct: 1485 SSPAQTTPPTTSKTTETRAS-GSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPP 1543
Query: 1012 PPPESHSSSLADHEYTAAGTFTGAQAGRTSQP 1043
P P + +SS++ T GT + ++P
Sbjct: 1544 PVPATSTSSMST---TTPGTSVVSSKPTLTEP 1572
Score = 33.5 bits (75), Expect = 1.1
Identities = 19/62 (30%), Positives = 32/62 (51%)
Query: 948 KSKKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPASTTPASTSTASSQASQEG 1007
+++ S+ TP T S ST+ + A T+TS +TP+ +TST+S + G
Sbjct: 1500 ETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPG 1559
Query: 1008 SS 1009
+S
Sbjct: 1560 TS 1561
Score = 32.0 bits (71), Expect = 3.3
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 978 STSTTPASTTPASTTPASTSTASSQASQEGSSP---------EPPPESHSSSLADHEYTA 1028
STS++PA TTP TT +T T +S +S S+P P ++S+ T
Sbjct: 1482 STSSSPAQTTP-PTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTP 1540
Query: 1029 AGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNT 1064
+ A + + PG + +P+ + P+ ++
Sbjct: 1541 SPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSS 1576
Score = 31.6 bits (70), Expect = 4.3
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)
Query: 985 STTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPM 1044
S++PA TTP +TS + + S+P P + S S A A GT T + S P
Sbjct: 1484 SSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA-RTTPAPGTATSVKK-TFSTPS 1541
Query: 1045 APGVFLTQRRPSASSPNNNTAAKG 1068
P V P+ S+ + +T G
Sbjct: 1542 PPPV------PATSTSSMSTTTPG 1559
Score = 31.2 bits (69), Expect = 5.6
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Query: 905 SPTARVGPSVPRQDR--PVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPN 962
+PT R + P P + V + T ++A ++ + ++ P
Sbjct: 1914 APTTRTTSASPASTTSGPGNTPSPVPTTST-ISAPTTSITSAPTTSTTSAPTSSTTSAPT 1972
Query: 963 TTSPSTSTSISAGTTSTSTTPASTTPASTTPAST 996
T++ S TS + + TSTT A TT ++ P +T
Sbjct: 1973 TSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006
>gi|169211979 PREDICTED: hypothetical protein [Homo sapiens]
Length = 168
Score = 52.8 bits (125), Expect = 2e-06
Identities = 19/44 (43%), Positives = 30/44 (68%)
Query: 18 RFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKST 61
RF I CD C +W++G CVG+ E+EA +D+Y C +C++ S+
Sbjct: 29 RFYIGCDLCTNWYYGECVGIAEKEAKKMDVYICNDCKQAQEGSS 72
>gi|239740940 PREDICTED: hypothetical protein XP_002344108 [Homo
sapiens]
Length = 168
Score = 52.8 bits (125), Expect = 2e-06
Identities = 18/40 (45%), Positives = 29/40 (72%)
Query: 15 DVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCE 54
+ +RF I CD C +W++G CVG+ E+EA +D+Y C +C+
Sbjct: 26 NTSRFYIGCDLCTNWYYGECVGIAEKEAKKMDVYICNDCK 65
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 51.2 bits (121), Expect = 5e-06
Identities = 138/629 (21%), Positives = 217/629 (34%), Gaps = 92/629 (14%)
Query: 467 REKEEPPSPIEATPPQSLLEKVSKKKTPKTVKMPKP---------SKIPKPPKPPKPP-- 515
+E E P + L E + TP+ + PK ++ +P + KPP
Sbjct: 1921 KEPVEQPRVTRKRLERELQEAAAVPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEG 1980
Query: 516 -RPPKTLKLKDGGKKKGKKSR----------ESASPTIPNLDLLEAHTKEALTKMEPPKK 564
R P++ K GG +GKK + E+ + P + + E + MEP
Sbjct: 1981 WRSPRSQKTAAGGGPQGKKGKNEPKVDATRPEATTEVGPQIGVKE-------SSMEPKAA 2033
Query: 565 GKATKSVLSVPNKDVVHMQNDVERLEIREQTKSKSEAKWKYKNSKPDSLLKMEEEQKLEK 624
+ S KD +N E + K + KNSK ++K
Sbjct: 2034 EEEAGSEQKRDRKDAGTDKNPPETAPVEVVEKKPAPE----KNSKSKRGRSRNSRLAVDK 2089
Query: 625 SPLAGNKDNKFS----FSFSNKKLLGSKALRPPTSPG---VFGALQNFKEDKPKPVRD-E 676
S N D S + + ++ G A+ P S G K D P ++ E
Sbjct: 2090 SASLKNVDAAVSPRGAAAQAGERESGVVAVSPEKSESPQKEDGLSSQLKSDPVDPDKEPE 2149
Query: 677 YEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAVLPTPVTKPKLDSAAYKSDDSSDE 736
E VS G + A + +L ++ A L SAAYK+D + E
Sbjct: 2150 KEDVSASGPSP------EATQLAKQMELEQAVEHIAKLAEASA-----SAAYKAD--APE 2196
Query: 737 GSLHIDTDTKPGRNARVKKESGSSAAGILDLLQASEEVGALEYNPSSQPPASPSTQEAIQ 796
G D D KP A + E ++ I++ + E N + PP +Q +Q
Sbjct: 2197 GLAPEDRD-KPAHQAS-ETELAAAIGSIINDISGEPE------NFPAPPPYPGESQTDLQ 2248
Query: 797 GMLSMANLQASDSCLQTTWGAGQAKGSSLAAHGARKNGGGSGKSAGKRLLKRAAKNSVDL 856
LQ S+ ++T + A +R SAG K A NS
Sbjct: 2249 PPAGAQALQPSEEGMETDEAVSGILETEAATESSRPPVNAPDPSAGPTDTKEARGNS--- 2305
Query: 857 DDYEEEQDHLDACFKDSDYVYPSLESDEDNPIFKSRSKKRKGSDDAPYSPTARVGPSVPR 916
E H K S V +L + +RS++++ ++ +P V VP
Sbjct: 2306 ----SETSHSVPEAKGSKEVEVTLVRKDKGRQKTTRSRRKRNTNKKVVAP---VESHVPE 2358
Query: 917 QDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLT------PNTTSPSTST 970
++ +G A+ E G + Q+E+Q K + + T P+T + S
Sbjct: 2359 SNQ--AQGESPAANE-GTTVQHPEAPQEEKQSEKPHSTPPQSCTSDLSKIPSTENSSQEI 2415
Query: 971 SISAGT-TSTSTTPASTTPASTTPASTSTAS--SQASQEGSSPEPPPESHSSSLADHEYT 1027
S+ T T S P P P + S S P PP S +
Sbjct: 2416 SVEERTPTKASVPPDLPPPPQPAPVDEEPQARFRVHSIIESDPVTPPSDPSIPIP----- 2470
Query: 1028 AAGTFTGAQAGRTSQPMAPGVFLTQRRPS 1056
T A + S P+A G Q P+
Sbjct: 2471 ---TLPSVTAAKLSPPVASGGIPHQSPPT 2496
Score = 43.1 bits (100), Expect = 0.001
Identities = 122/680 (17%), Positives = 223/680 (32%), Gaps = 132/680 (19%)
Query: 441 LSENASKAVRPEVNTVASSDEV-----CDGDREKEEPPSPIE------------ATPPQ- 482
+SE A A P V ++V D D+E P+ +E A PP
Sbjct: 1679 VSEEAKPASEPAPAPVEQLEQVDLPPGADPDKEAAMMPAGVEEGSSGDQPPYLDAKPPTP 1738
Query: 483 ----SLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSRESA 538
S E + T + KP++ + PK +P T + +K + + ES
Sbjct: 1739 GASFSQAESNVDPEPDSTQPLSKPAQKSEEANEPKAEKPDATADAEPDANQKAEAAPESQ 1798
Query: 539 SPTIPNLDLLEAHTKEALTKMEPPKKGKATK-----SVLSVPNKDVVHMQNDVERLEIRE 593
P +L++ K + P K K +K + +S+ K V ++R +++
Sbjct: 1799 PPASEDLEV----DPPVAAKDKKPNKSKRSKTPVQAAAVSIVEKPVTRKSERIDREKLKR 1854
Query: 594 QTKSKSEAKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRPP 653
+ EA+ LL+++ E EK +K++ L S+ R
Sbjct: 1855 SNSPRGEAQ---------KLLELKME--AEKITRTASKNSAADLEHPEPSLPLSRTRR-- 1901
Query: 654 TSPGVFGALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKAV 713
+ VR Y + D + P+ + + KR L L + A
Sbjct: 1902 -----------------RNVRSVYATMGDHENRSPVKEPVEQPRVTRKR-LERELQEAAA 1943
Query: 714 LPTPVTKPKLDSAAYKSDDSSDEGSLHIDTDTKPGRNARVKKESGSSAAGILDLLQASEE 773
+PT + + ++D+ + + KP R + ++A G
Sbjct: 1944 VPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGG---------- 1993
Query: 774 VGALEYNPSSQPPASPSTQEAIQGMLSMANLQASDSCLQTTWGAGQ--AKGSSLAAHGAR 831
G ++P + EA TT Q K SS+ A
Sbjct: 1994 -GPQGKKGKNEPKVDATRPEA------------------TTEVGPQIGVKESSMEPKAAE 2034
Query: 832 KNGGGSGKSAGKRLLKRAAKNSVDLDDYEEEQDHLDACFKDSDYVYPSLESDEDNPIFKS 891
+ G E+++D DA + +E E P +
Sbjct: 2035 EEAGS-----------------------EQKRDRKDAGTDKNPPETAPVEVVEKKPAPEK 2071
Query: 892 RSKKRKG---SDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQK 948
SK ++G + +A + +V P + E+G+ A + + S+ +++
Sbjct: 2072 NSKSKRGRSRNSRLAVDKSASL-KNVDAAVSPRGAAAQAGERESGVVAVSPEKSESPQKE 2130
Query: 949 SKKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTP--------ASTTPASTSTAS 1000
K P ++G + +T A A AS S A
Sbjct: 2131 DGLSSQLKSDPVDPDKEPEKEDVSASGPSPEATQLAKQMELEQAVEHIAKLAEASASAAY 2190
Query: 1001 SQASQEGSSPE----PPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMAPGVFLTQRRPS 1056
+ EG +PE P ++ + LA + +G + P PG T +P
Sbjct: 2191 KADAPEGLAPEDRDKPAHQASETELAAAIGSIINDISGEPENFPAPPPYPGESQTDLQPP 2250
Query: 1057 ASSPNNNTAAKGKRTKKGMA 1076
A + + +G T + ++
Sbjct: 2251 AGAQALQPSEEGMETDEAVS 2270
Score = 33.9 bits (76), Expect = 0.87
Identities = 30/116 (25%), Positives = 46/116 (39%), Gaps = 30/116 (25%)
Query: 410 TKKQALAEHEDELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVN--TVASSDEVCDGDR 467
T K+ +A E +PE N ++ P N T E ++
Sbjct: 2344 TNKKVVAPVESHVPE------------------SNQAQGESPAANEGTTVQHPEAPQEEK 2385
Query: 468 EKEEPPSPIEATPPQSLLEKVSKKKTPK------TVKMPKPSKIPKPPKPPKPPRP 517
+ E+P S TPPQS +SK + + +V+ P+K PP P PP+P
Sbjct: 2386 QSEKPHS----TPPQSCTSDLSKIPSTENSSQEISVEERTPTKASVPPDLPPPPQP 2437
Score = 30.4 bits (67), Expect = 9.6
Identities = 51/229 (22%), Positives = 84/229 (36%), Gaps = 30/229 (13%)
Query: 872 DSDYVYPSLESDEDNPIF---KSRSKKRKGSDDAPYSPTARVG---PSVPRQDRPVREGT 925
D DY E + ++ +SRS R + D Y P AR PSV +D + T
Sbjct: 166 DQDYYRDPRERTLQHGLYYASRSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDIT 225
Query: 926 RVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPAS 985
R + ++ Q S+ + SP +S S + ++ +
Sbjct: 226 R---------EVRGRRPERNYQHSRSR------------SPHSSQSRNQSPQRLASQASR 264
Query: 986 TTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHEYTAAGTFTGAQAGRTSQPMA 1045
T + + S S +SS S SS S SSS + + A + A TSQ +
Sbjct: 265 PTRSPSGSGSRSRSSSSDSISSSSSTSSDSSDSSSSSSDDSPARSVQSAAVPAPTSQ-LL 323
Query: 1046 PGVFLTQRRPSASSPNNNTAAKGKRT--KKGMATAKQRLGKILKIHRNG 1092
+ + R S N + T K G+ ++ GK+ + +G
Sbjct: 324 SSLEKDEPRKSFGIKVQNLPVRSTDTSLKDGLFHEFKKFGKVTSVQIHG 372
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 51.2 bits (121), Expect = 5e-06
Identities = 72/290 (24%), Positives = 120/290 (41%), Gaps = 30/290 (10%)
Query: 436 AKEIRLSENASKAVRPEVNTVASSDEVCDGDREKEEPPSPIEATPPQSLLEKVSKKKTPK 495
AKE + E S+ V + VA + K E P ++ P+S +E+ K PK
Sbjct: 582 AKEEKKVEEKSEEVATKEELVADA---------KVEKPEKAKSPVPKSPVEEKGKSPVPK 632
Query: 496 T-VKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKS--RESASPTIPNLDLLEAHT 552
+ V+ S +PK P K P +++ GK KS E A +P + EA +
Sbjct: 633 SPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKS 692
Query: 553 KEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIREQTKS----KSEAKWKYKNS 608
K + K E +K + K V P ++ V + + + ++ E+ K+ K EA +
Sbjct: 693 KAEVGKGE--QKEEEEKEVKEAPKEEKVEKKEEKPK-DVPEKKKAESPVKEEAVAEVVTI 749
Query: 609 KPDSLLKMEEEQKLEKSPLAGNKDNK-------FSFSFSNKKLLGSKALRPPTSPGVFGA 661
+ +E+E K E PL K+ + S+K GS+ + V G
Sbjct: 750 TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGK 809
Query: 662 LQNFKEDKPK-PVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDK 710
+ +E K K R+E + V +G +D P KK K + ++ K
Sbjct: 810 EEVEQETKEKGSGREEEKGVVTNG---LDLSPADEKKGGDKSEEKVVVTK 856
Score = 40.4 bits (93), Expect = 0.009
Identities = 73/351 (20%), Positives = 143/351 (40%), Gaps = 34/351 (9%)
Query: 421 ELPEHFKPSQLIKDLAKEIRLSENASK------AVRPEVNTVASSDEVCDGDREKEEPPS 474
E P+ + ++++ +E ++ + S+ A+ E+ V+ +E + EKEE P
Sbjct: 442 EAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEEL-AVSMKEEKKEAAEEKEEEP- 499
Query: 475 PIEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPP--KTLKLKDGGKKKGK 532
EA + +K K T VK + K + + + K+ + ++GG +K
Sbjct: 500 --EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEG 557
Query: 533 KSRESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIR 592
S + EA +EA K E + K+ + V K+ + VE+ E
Sbjct: 558 SSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE----VATKEELVADAKVEKPEKA 613
Query: 593 EQTKSKSEAKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKLLGSKALRP 652
+ KS + K K+ P S ++ + + + KSP+ + K + K P
Sbjct: 614 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP-----KSPVEEKGKSP 668
Query: 653 PTSPGVFGALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKKA 712
+ V + K PK +E + ++ G+ + E + K APK + ++KK
Sbjct: 669 VSKSPV---EEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE---KVEKKE 722
Query: 713 VLPTPVTKPKLDSAAYKSDDSSD------EGSLHIDTDTK-PGRNARVKKE 756
P V + K + K + ++ +H++ +TK G+ + +KE
Sbjct: 723 EKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKE 773
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,375,532
Number of Sequences: 37866
Number of extensions: 2630237
Number of successful extensions: 38820
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 438
Number of HSP's successfully gapped in prelim test: 1104
Number of HSP's that attempted gapping in prelim test: 18722
Number of HSP's gapped (non-prelim): 11555
length of query: 1096
length of database: 18,247,518
effective HSP length: 113
effective length of query: 983
effective length of database: 13,968,660
effective search space: 13731192780
effective search space used: 13731192780
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.