Guide to the Human Genome
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Search of human proteins with 116812575

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116812575 high glucose-regulated protein 8 [Homo sapiens]
         (579 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116812575 high glucose-regulated protein 8 [Homo sapiens]         1193   0.0  
gi|116235460 YTH domain family, member 3 [Homo sapiens]               797   0.0  
gi|31377750 YTH domain family, member 1 [Homo sapiens]                747   0.0  
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           71   2e-12
gi|38505213 YTH domain containing 2 [Homo sapiens]                     66   8e-11
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           65   2e-10
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    48   2e-05
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    47   6e-05
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    45   1e-04
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    45   1e-04
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    45   1e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    44   3e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    44   3e-04
gi|153791535 general control of amino acid synthesis 5-like 2 [H...    44   4e-04
gi|38683860 insulin receptor substrate 2 [Homo sapiens]                44   5e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          44   5e-04
gi|150378539 piccolo isoform 1 [Homo sapiens]                          44   5e-04
gi|40807465 zinc finger protein 341 [Homo sapiens]                     44   5e-04
gi|169163728 PREDICTED: hypothetical protein [Homo sapiens]            43   7e-04
gi|169163708 PREDICTED: hypothetical protein [Homo sapiens]            43   7e-04
gi|169163019 PREDICTED: hypothetical protein [Homo sapiens]            43   7e-04
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          43   0.001
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          43   0.001
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          43   0.001
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    43   0.001
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       43   0.001
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                43   0.001
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    42   0.001
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    42   0.001
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         42   0.002

>gi|116812575 high glucose-regulated protein 8 [Homo sapiens]
          Length = 579

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 579/579 (100%), Positives = 579/579 (100%)

Query: 1   MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY 60
           MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY
Sbjct: 1   MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY 60

Query: 61  SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH 120
           SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH
Sbjct: 61  SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH 120

Query: 121 GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP 180
           GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP
Sbjct: 121 GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP 180

Query: 181 GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA 240
           GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA
Sbjct: 181 GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA 240

Query: 241 DIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT 300
           DIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT
Sbjct: 241 DIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT 300

Query: 301 QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSG 360
           QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSG
Sbjct: 301 QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSG 360

Query: 361 FGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSE 420
           FGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSE
Sbjct: 361 FGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSE 420

Query: 421 DDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYN 480
           DDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYN
Sbjct: 421 DDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYN 480

Query: 481 TCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQV 540
           TCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQV
Sbjct: 481 TCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQV 540

Query: 541 LKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK 579
           LKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK
Sbjct: 541 LKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK 579


>gi|116235460 YTH domain family, member 3 [Homo sapiens]
          Length = 585

 Score =  797 bits (2059), Expect = 0.0
 Identities = 405/598 (67%), Positives = 468/598 (78%), Gaps = 42/598 (7%)

Query: 1   MSASSLLEQRPKGQGNKV--QNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPS 58
           MSA+S+ +QRPKGQGNKV  QNGS+HQKD +NDDDFEPYLS Q   +N+Y  MSD Y+PS
Sbjct: 1   MSATSV-DQRPKGQGNKVSVQNGSIHQKDAVNDDDFEPYLSSQTNQSNSYPPMSDPYMPS 59

Query: 59  YYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTP-FL 117
           YY+PSIGF YSLGEAAWST GD  MPYLT+YGQ+SNGE H++PD +F QPGALG+TP FL
Sbjct: 60  YYAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFL 119

Query: 118 GQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLN 177
           GQHGFNFFP   DFS WG + SQGQSTQSS YSS+Y Y PSSLG A+ DGQ+ F N+TL+
Sbjct: 120 GQHGFNFFPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLS 179

Query: 178 KAPGMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPA 237
           K PG+++I+QGM  LK+G  ++ + V K VG+A+ S  +TS  +A+NS+PP + A PKP 
Sbjct: 180 KVPGISSIEQGMTGLKIGG-DLTAAVTKTVGTALSSSGMTS--IATNSVPPVSSAAPKPT 236

Query: 238 SWADIASKPAKQQPKLKTKN--GIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALV-- 293
           SWA IA KPAK QPKLK K   GI GS++PPPPIKHNM+IGTWD KG V KAP    V  
Sbjct: 237 SWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLP 296

Query: 294 -QNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQ---------PAQLSVQQ 343
            Q I Q     PQP+ Q     PP+ Q+ + QQ QP PP P Q         P Q+  QQ
Sbjct: 297 PQTIIQ----QPQPLIQP----PPLVQSQLPQQ-QPQPPQPQQQQGPQPQAQPHQVQPQQ 347

Query: 344 QAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTPS-------EPHPVLEKLRSIN 396
           Q  Q  RWVAPRNRG+GF  N    NG G    G G  P        E HPVLEKL++IN
Sbjct: 348 QQLQ-NRWVAPRNRGAGFNQN----NGAGSENFGLGVVPVSASPSSVEVHPVLEKLKAIN 402

Query: 397 NYNPKDFDWNLKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVY 456
           NYNPKDFDWNLK+GRVFIIKSYSEDDIHRSIKY+IWCSTEHGNKRLDAAYRS+NGKGP+Y
Sbjct: 403 NYNPKDFDWNLKNGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLY 462

Query: 457 LLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLE 516
           LLFSVNGSGHFCGVAEMKS VDYN  AGVWSQDKWKG+F+V+WIFVKDVPN+QLRHIRLE
Sbjct: 463 LLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLE 522

Query: 517 NNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKER 574
           NN+NKPVTNSRDTQEVPLEKAKQVLKIIA++KHTTSIFDDF+HYEKRQEEEE++++ER
Sbjct: 523 NNDNKPVTNSRDTQEVPLEKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRER 580


>gi|31377750 YTH domain family, member 1 [Homo sapiens]
          Length = 559

 Score =  747 bits (1929), Expect = 0.0
 Identities = 378/584 (64%), Positives = 440/584 (75%), Gaps = 31/584 (5%)

Query: 1   MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY 60
           MSA+S+  QR KGQ NKVQNGS+HQKD ++D+DFEPYL+ Q+  +N+Y +MSD YL SYY
Sbjct: 1   MSATSVDTQRTKGQDNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYY 60

Query: 61  SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH 120
            PSIGF YSL EA WST GD  +PYLT+YGQLSNG+ HF+ DA+FGQPG LG+  +  QH
Sbjct: 61  PPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIY--QH 118

Query: 121 GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP 180
            FNFFP    FSAWG + SQGQ TQSS Y S+Y Y PSSLGG ++DGQ  F ++TL+KAP
Sbjct: 119 RFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAP 178

Query: 181 GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA 240
           GMN+++QGM  LK+G  +V+S+  K VGS V S ++T  +++ N      +   KP SWA
Sbjct: 179 GMNSLEQGMVGLKIG--DVSSSAVKTVGSVVSSVALTG-VLSGNGGTNVNMPVSKPTSWA 235

Query: 241 DIASKPAKQQPKLKTKNG-IAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQP 299
            IASKPAK QPK+KTK+G + G  LPPPPIKHNMDIGTWDNKGPV KAP    V      
Sbjct: 236 AIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAP----VPQQAPS 291

Query: 300 TQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQP-TRWVAPRNRG 358
            Q +PQP                 Q  QPLP  PP  AQ   Q     P TRWVAPRNR 
Sbjct: 292 PQAAPQPQ----------------QVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRN 335

Query: 359 SGFGHNG---VDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFII 415
           + FG +G    D N  G  Q  S  +  E HPVLEKL++ ++YNPK+F+WNLK GRVFII
Sbjct: 336 AAFGQSGGAGSDSNSPGNVQPNSAPSV-ESHPVLEKLKAAHSYNPKEFEWNLKSGRVFII 394

Query: 416 KSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKS 475
           KSYSEDDIHRSIKY+IWCSTEHGNKRLD+A+R M+ KGPVYLLFSVNGSGHFCGVAEMKS
Sbjct: 395 KSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKS 454

Query: 476 AVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLE 535
            VDY T AGVWSQDKWKG+FDV+WIFVKDVPN+QLRHIRLENN+NKPVTNSRDTQEVPLE
Sbjct: 455 PVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLE 514

Query: 536 KAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK 579
           KAKQVLKII+SYKHTTSIFDDF+HYEKRQEEEE V+KERQ R K
Sbjct: 515 KAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKERQSRNK 558


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 52/192 (27%), Positives = 86/192 (44%), Gaps = 10/192 (5%)

Query: 355 RNRGSGFGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFI 414
           R R  G      D +G   S++ +GS       +   +R++         + L+  R F+
Sbjct: 301 RKRARGISPIVFDRSGSSASESYAGSEKKH-EKLSSSVRAVRKDQTSKLKYVLQDARFFL 359

Query: 415 IKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMK 474
           IKS + +++  +    +W +     K+L+ A+RS      V L+FSV  SG F G A + 
Sbjct: 360 IKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARS---VILIFSVRESGKFQGFARLS 416

Query: 475 SAVDYNTCAGVW------SQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRD 528
           S   +      W      S     G F + WI  +++P ++  H+    NE+KPV   RD
Sbjct: 417 SESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRD 476

Query: 529 TQEVPLEKAKQV 540
            QE+ LE   Q+
Sbjct: 477 GQEIELECGTQL 488


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 44/133 (33%), Positives = 67/133 (50%), Gaps = 4/133 (3%)

Query: 411  RVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGV 470
            R FI+KS +  ++  S +  IW +T    ++L+ A+   +    VYL+FSV GSGHF G 
Sbjct: 1289 RYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESS---IVYLVFSVQGSGHFQGF 1345

Query: 471  AEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQ 530
            + M S +        W      G F V WI  + +P     H+    N+NK V  SRD Q
Sbjct: 1346 SRMSSEIGREKSQD-WGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQ 1404

Query: 531  EVPLEKAKQVLKI 543
            E+     +Q+L++
Sbjct: 1405 ELEPLVGEQLLQL 1417


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 43/140 (30%), Positives = 68/140 (48%), Gaps = 9/140 (6%)

Query: 407 LKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGH 466
           L+  R F+IKS + +++  +    +W +     K+L+ A+RS      V L+FSV  SG 
Sbjct: 334 LQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARS---VILIFSVRESGK 390

Query: 467 FCGVAEMKSAVDYNTCAGVW------SQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNEN 520
           F G A + S   +      W      S     G F + WI  +++P ++  H+    NE+
Sbjct: 391 FQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEH 450

Query: 521 KPVTNSRDTQEVPLEKAKQV 540
           KPV   RD QE+ LE   Q+
Sbjct: 451 KPVKIGRDGQEIELECGTQL 470


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 55/217 (25%), Positives = 83/217 (38%), Gaps = 23/217 (10%)

Query: 182 MNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWAD 241
           + +++  +AA       +A   P+V  +A G+     N V S S  PA  A   PA+ A+
Sbjct: 26  VGSLESQLAASAAHHHHLAPRTPEVRAAAAGA---LGNHVVSGS--PAGAAGAGPAAPAE 80

Query: 242 IASKPAKQQPKL-KTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT 300
            A   A + P   + + G  G   P PP      +       P   AP  A ++      
Sbjct: 81  GAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLV-------PAGPAPPAAKLR------ 127

Query: 301 QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSG 360
              P P G   + +P  A A+V    +P P  P +PA  +     A P     P   G G
Sbjct: 128 ---PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP-GPGPG 183

Query: 361 FGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINN 397
            G     G G  Q+  GS +  +  H     +  +NN
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNN 220



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 53/207 (25%), Positives = 73/207 (35%), Gaps = 28/207 (13%)

Query: 157 PSSLGGAM-IDGQSAFANETLNKAPGMNTIDQGMAAL----KLGSTEVASNVPKVVGSAV 211
           P+  G A  ++G +A  N     AP ++ ++ G AAL    K  +       P  VG+A 
Sbjct: 189 PAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAA 248

Query: 212 GSG-SITSNIVASNSLPPATIAPPKPASWADIA-----------SKPAKQQPKLKTKNGI 259
               +  S   A     PA   PP P + A +A           + PA   P      G 
Sbjct: 249 PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGS 308

Query: 260 AGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQP---TQGSPQPVGQQANNSPP 316
           AG++  P P       G     GP A A + A       P    Q +P      A + P 
Sbjct: 309 AGAAPAPAPAAGG-PAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPA 367

Query: 317 VAQASV-------GQQTQPLPPPPPQP 336
              AS+       G    P   PPP P
Sbjct: 368 STAASMVIGPTMQGALPSPAAVPPPAP 394



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 40/155 (25%), Positives = 53/155 (34%), Gaps = 19/155 (12%)

Query: 204 PKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSS 263
           P   GSA     + +    +    PA   P KPA  A +A++               G  
Sbjct: 128 PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPG 187

Query: 264 LPPPP-IKHNMDIGTWDNKGPVAKAPSQALVQN-----IGQPTQGSPQPVGQQ------- 310
            P  P     ++          A AP+ +LV N     +  P   +P  V Q        
Sbjct: 188 KPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAA 247

Query: 311 -----ANNSPPVAQASVGQQTQPLPPPPPQPAQLS 340
                A  SPP A A       P PPPPP PA L+
Sbjct: 248 APPAPAAPSPPAAPAPAAPAAAP-PPPPPAPATLA 281


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 45/151 (29%), Positives = 52/151 (34%), Gaps = 22/151 (14%)

Query: 224 NSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGP 283
           +SLPP    PP     +D +  PA     LK K G  G  LP PP          D+  P
Sbjct: 514 SSLPP----PPPVRRSSDTSGSPATP---LKAK-GTGGGGLPAPP----------DDFLP 555

Query: 284 VAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQ 343
               P       +  P     +P        PP      G +  P PPPPP PA   V  
Sbjct: 556 PPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPD 615

Query: 344 QAAQP----TRWVAPRNRGSGFGHNGVDGNG 370
            A  P     R   P  R    GH G  G G
Sbjct: 616 SARPPPAVAKRPPVPPKRQENPGHPGGAGGG 646



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 4/53 (7%)

Query: 295 NIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQ 347
           ++G  T  +   + Q  ++ PP     V     PLPPPPP+P  LS +++ AQ
Sbjct: 109 SLGYGTNVAATGISQYEDDLPPPPADPV--LDLPLPPPPPEP--LSQEEEEAQ 157


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 83/353 (23%), Positives = 127/353 (35%), Gaps = 75/353 (21%)

Query: 35  EPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSN 94
           +PY S Q +P   +      YLPS           + +  + T          S   L+ 
Sbjct: 553 QPYYSQQPQP--PHLPPQAQYLPSQSQQRYQPQQDMSQEGYGT---------RSQPPLAP 601

Query: 95  GEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYA 154
           G+P+   D    Q     S P L     +  P+G + +     S+ G ST S G  SN A
Sbjct: 602 GKPNH-EDLNLIQQERPSSLPDLSG-SIDDLPTGTEATLSSAVSASG-STSSQGDQSNPA 658

Query: 155 YAPSSLGGAMIDGQSAFANETLNKAPGMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSG 214
            +P S                 + +P +++I  G +             P  VGS VGS 
Sbjct: 659 QSPFSP----------------HASPHLSSIPGGPS-------------PSPVGSPVGSN 689

Query: 215 SITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNG-IAGSSLPPPPIKHNM 273
              S  ++  S+P + + P  P S ++ +S PA  Q  +  + G +AG+   P   ++  
Sbjct: 690 QSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQY-- 747

Query: 274 DIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPP 333
                   GP    PS +            P P GQ        A  S  QQ+       
Sbjct: 748 --------GPQQTGPSMS----------PHPSPGGQMH------AGISSFQQSNSSGTYG 783

Query: 334 PQPAQLSVQQQAAQPTRWV-APRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEP 385
           PQ +Q   Q   ++P  +   P    SG G     G G+  +    G  PS+P
Sbjct: 784 PQMSQYGPQGNYSRPPAYSGVPSASYSGPG----PGMGISANNQMHGQGPSQP 832


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 83/353 (23%), Positives = 127/353 (35%), Gaps = 75/353 (21%)

Query: 35  EPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSN 94
           +PY S Q +P   +      YLPS           + +  + T          S   L+ 
Sbjct: 540 QPYYSQQPQP--PHLPPQAQYLPSQSQQRYQPQQDMSQEGYGT---------RSQPPLAP 588

Query: 95  GEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYA 154
           G+P+   D    Q     S P L     +  P+G + +     S+ G ST S G  SN A
Sbjct: 589 GKPNH-EDLNLIQQERPSSLPDLSG-SIDDLPTGTEATLSSAVSASG-STSSQGDQSNPA 645

Query: 155 YAPSSLGGAMIDGQSAFANETLNKAPGMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSG 214
            +P S                 + +P +++I  G +             P  VGS VGS 
Sbjct: 646 QSPFSP----------------HASPHLSSIPGGPS-------------PSPVGSPVGSN 676

Query: 215 SITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNG-IAGSSLPPPPIKHNM 273
              S  ++  S+P + + P  P S ++ +S PA  Q  +  + G +AG+   P   ++  
Sbjct: 677 QSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQY-- 734

Query: 274 DIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPP 333
                   GP    PS +            P P GQ        A  S  QQ+       
Sbjct: 735 --------GPQQTGPSMS----------PHPSPGGQMH------AGISSFQQSNSSGTYG 770

Query: 334 PQPAQLSVQQQAAQPTRWV-APRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEP 385
           PQ +Q   Q   ++P  +   P    SG G     G G+  +    G  PS+P
Sbjct: 771 PQMSQYGPQGNYSRPPAYSGVPSASYSGPG----PGMGISANNQMHGQGPSQP 819


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 83/353 (23%), Positives = 127/353 (35%), Gaps = 75/353 (21%)

Query: 35  EPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSN 94
           +PY S Q +P   +      YLPS           + +  + T          S   L+ 
Sbjct: 540 QPYYSQQPQP--PHLPPQAQYLPSQSQQRYQPQQDMSQEGYGT---------RSQPPLAP 588

Query: 95  GEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYA 154
           G+P+   D    Q     S P L     +  P+G + +     S+ G ST S G  SN A
Sbjct: 589 GKPNH-EDLNLIQQERPSSLPDLSG-SIDDLPTGTEATLSSAVSASG-STSSQGDQSNPA 645

Query: 155 YAPSSLGGAMIDGQSAFANETLNKAPGMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSG 214
            +P S                 + +P +++I  G +             P  VGS VGS 
Sbjct: 646 QSPFSP----------------HASPHLSSIPGGPS-------------PSPVGSPVGSN 676

Query: 215 SITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNG-IAGSSLPPPPIKHNM 273
              S  ++  S+P + + P  P S ++ +S PA  Q  +  + G +AG+   P   ++  
Sbjct: 677 QSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQY-- 734

Query: 274 DIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPP 333
                   GP    PS +            P P GQ        A  S  QQ+       
Sbjct: 735 --------GPQQTGPSMS----------PHPSPGGQMH------AGISSFQQSNSSGTYG 770

Query: 334 PQPAQLSVQQQAAQPTRWV-APRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEP 385
           PQ +Q   Q   ++P  +   P    SG G     G G+  +    G  PS+P
Sbjct: 771 PQMSQYGPQGNYSRPPAYSGVPSASYSGPG----PGMGISANNQMHGQGPSQP 819


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 36/139 (25%), Positives = 60/139 (43%), Gaps = 10/139 (7%)

Query: 208 GSAVGSGSITSNIVASNSLPPATIAPPKPASWAD-IASKPAKQQPKLKTKNGIAGSSLPP 266
           G+A+G GSI  + ++S+S  P +  PP P + +  +  KP    P +  +  I   ++PP
Sbjct: 227 GTALGGGSIRQSPLSSSS--PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP 284

Query: 267 PPIKHNM-DIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQ 325
           PP ++N   + +       ++AP      +   P    P   G       P    S+   
Sbjct: 285 PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344

Query: 326 TQPLPPP------PPQPAQ 338
           T PLP P      PP P++
Sbjct: 345 TPPLPSPGRSGPLPPPPSE 363



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 33/140 (23%)

Query: 228 PATIAPPKPASWADIASKPAKQ-QPKLK--TKNGIAGSSLPPPPIKHNMDIG-------- 276
           P +I PP P++   I S P  +  P +    +    G + PP P      +G        
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSP 239

Query: 277 -----TWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQA-------------NNSPPVA 318
                 + N+ P+   PS+AL      P    P PVG +              NN PPV 
Sbjct: 240 LSSSSPFSNRPPLPPTPSRALDDKPPPP----PPPVGNRPSIHREAVPPPPPQNNKPPVP 295

Query: 319 QASVGQQTQPLPPPPPQPAQ 338
                  +   PPPPP P++
Sbjct: 296 STPRPSASSQAPPPPPPPSR 315



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 19/101 (18%)

Query: 302 GSPQPVGQQANNSPPVAQASVGQQTQPLPPP---PPQPAQLS------------VQQQAA 346
           G P+P   Q N  PP  +  VG +   +PPP    P+P Q S             +Q + 
Sbjct: 160 GPPEP---QRNRMPP-PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP 215

Query: 347 QPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEPHP 387
            PT    P NRG+  G   +  + +  S   S   P  P P
Sbjct: 216 GPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTP 256



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 33/140 (23%), Positives = 50/140 (35%), Gaps = 16/140 (11%)

Query: 222 ASNSLPPATIAPPKPASWADIASKPAKQQ-PKLKTKNGIAGSSLPPPPIKHNMDIGTWDN 280
           AS+  PP    P +P       S     + P+L  +N    SS PP P            
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP--------GR 353

Query: 281 KGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLS 340
            GP+   PS+       +P      P G+     PP   +  G  ++ LP  P  P++  
Sbjct: 354 SGPLPPPPSE-------RPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSG 406

Query: 341 VQQQAAQPTRWVAPRNRGSG 360
           V    + P   + P    +G
Sbjct: 407 VDSPRSGPRPPLPPDRPSAG 426


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 36/139 (25%), Positives = 60/139 (43%), Gaps = 10/139 (7%)

Query: 208 GSAVGSGSITSNIVASNSLPPATIAPPKPASWAD-IASKPAKQQPKLKTKNGIAGSSLPP 266
           G+A+G GSI  + ++S+S  P +  PP P + +  +  KP    P +  +  I   ++PP
Sbjct: 227 GTALGGGSIRQSPLSSSS--PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP 284

Query: 267 PPIKHNM-DIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQ 325
           PP ++N   + +       ++AP      +   P    P   G       P    S+   
Sbjct: 285 PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344

Query: 326 TQPLPPP------PPQPAQ 338
           T PLP P      PP P++
Sbjct: 345 TPPLPSPGRSGPLPPPPSE 363



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 33/140 (23%)

Query: 228 PATIAPPKPASWADIASKPAKQ-QPKLK--TKNGIAGSSLPPPPIKHNMDIG-------- 276
           P +I PP P++   I S P  +  P +    +    G + PP P      +G        
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSP 239

Query: 277 -----TWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQA-------------NNSPPVA 318
                 + N+ P+   PS+AL      P    P PVG +              NN PPV 
Sbjct: 240 LSSSSPFSNRPPLPPTPSRALDDKPPPP----PPPVGNRPSIHREAVPPPPPQNNKPPVP 295

Query: 319 QASVGQQTQPLPPPPPQPAQ 338
                  +   PPPPP P++
Sbjct: 296 STPRPSASSQAPPPPPPPSR 315



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 19/101 (18%)

Query: 302 GSPQPVGQQANNSPPVAQASVGQQTQPLPPP---PPQPAQLS------------VQQQAA 346
           G P+P   Q N  PP  +  VG +   +PPP    P+P Q S             +Q + 
Sbjct: 160 GPPEP---QRNRMPP-PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP 215

Query: 347 QPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEPHP 387
            PT    P NRG+  G   +  + +  S   S   P  P P
Sbjct: 216 GPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTP 256



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 33/140 (23%), Positives = 50/140 (35%), Gaps = 16/140 (11%)

Query: 222 ASNSLPPATIAPPKPASWADIASKPAKQQ-PKLKTKNGIAGSSLPPPPIKHNMDIGTWDN 280
           AS+  PP    P +P       S     + P+L  +N    SS PP P            
Sbjct: 302 ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP--------GR 353

Query: 281 KGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLS 340
            GP+   PS+       +P      P G+     PP   +  G  ++ LP  P  P++  
Sbjct: 354 SGPLPPPPSE-------RPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSG 406

Query: 341 VQQQAAQPTRWVAPRNRGSG 360
           V    + P   + P    +G
Sbjct: 407 VDSPRSGPRPPLPPDRPSAG 426


>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
           sapiens]
          Length = 837

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 28/76 (36%), Positives = 30/76 (39%), Gaps = 2/76 (2%)

Query: 310 QANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGN 369
           QA    P AQ    Q   P P P P PA          PT   AP    +  G  G  G 
Sbjct: 6   QAPTPAPAAQPRPLQS--PAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGP 63

Query: 370 GVGQSQAGSGSTPSEP 385
           GVG   AGSG  P+ P
Sbjct: 64  GVGSGGAGSGGDPARP 79


>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
          Length = 1338

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 46/168 (27%), Positives = 63/168 (37%), Gaps = 17/168 (10%)

Query: 227  PPATIAPPKP---ASWADIASKPAKQQPKLKTKNGIAGSSLPP---PPIKHNMDIGTWDN 280
            P A ++PP P   AS A  +S  +   P     +G  G+S       P+   M++     
Sbjct: 927  PGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSP 986

Query: 281  KGPVAKAPSQALVQNIG---QPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPA 337
            K P   APS   V ++     P   SP P        PP   AS     QP PPPPP P 
Sbjct: 987  KSPKPGAPSGHPVGSLDGLLSPEASSPYPP------LPPRPSASPSSSLQP-PPPPPAPG 1039

Query: 338  QLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEP 385
            +L     A+       P    S    +  D     +   G  +TP +P
Sbjct: 1040 ELYRLPPASAVATAQGP-GAASSLSSDTGDNGDYTEMAFGVAATPPQP 1086



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 20/60 (33%), Positives = 23/60 (38%), Gaps = 7/60 (11%)

Query: 323  GQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTP 382
            G   QP PPPPP P       Q    + W   R+ G      GV   G G    G G+ P
Sbjct: 1263 GLPPQPQPPPPPLP-------QPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALP 1315


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 39/151 (25%), Positives = 51/151 (33%), Gaps = 17/151 (11%)

Query: 205 KVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQP-KLKTKNGIAGSS 263
           K+     G G  ++        P     P KP       +KP  QQP   K  +   GS+
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 264 LPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVG 323
            PPP              GP   +P Q           GS +P  QQ + + P AQ S  
Sbjct: 508 KPPP-----------QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556

Query: 324 QQTQ-----PLPPPPPQPAQLSVQQQAAQPT 349
             +Q     PL PP   P+      Q    T
Sbjct: 557 PVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 51/185 (27%), Positives = 68/185 (36%), Gaps = 26/185 (14%)

Query: 218 SNIVASNSLPPATIAPPKPASWADIASKPAKQQP-KLKTKNGIAGSSLPPPPIKHNMDIG 276
           ++IV   S+ P+  +P KP        KP  QQP   K++ G A     P  +   +   
Sbjct: 286 ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ 345

Query: 277 TWDNKGPV-----AKAPSQAL------VQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQ 325
               K PV      K P+Q L       Q  G     S QP G +A   PP    +  QQ
Sbjct: 346 PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP-GPKALAQPPGVGKTPAQQ 404

Query: 326 TQPLPPPPPQ---PAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQ---SQAGSG 379
             P  PP  Q   P  L+ Q     P +   P           V   G G+    QAG G
Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK-------TPVQQPGPGKIPAQQAGPG 457

Query: 380 STPSE 384
            T ++
Sbjct: 458 KTSAQ 462



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 36/119 (30%), Positives = 48/119 (40%), Gaps = 22/119 (18%)

Query: 235 KPASWADIASKPAKQQPKLK-----TKNGIAGSSLPPPPIKHNMDIGTWD--NKGPVAKA 287
           K A   D+A  P+  QPKLK     T + ++ SS  P       D       +K P  K 
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702

Query: 288 PSQALVQNIGQPT-QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQA 345
           P       + QPT  GSP    +Q    PP A       +   P PP +P+  S Q +A
Sbjct: 703 PPPL----VKQPTLHGSPSAKAKQ----PPEA------DSLSKPAPPKEPSVPSEQDKA 747



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 6/141 (4%)

Query: 204 PKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSS 263
           PK +    G G   +        P   +  PKP +       PAK     KT     G  
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447

Query: 264 LPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSP-QPVGQQANNSPPVAQASV 322
             P   +      +    GP  K PSQ        P Q  P +P  QQ  ++ P +Q   
Sbjct: 448 KIPAQ-QAGPGKTSAQQTGP-TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP- 504

Query: 323 GQQTQPLPPPPPQPAQLSVQQ 343
              T+P PP  P PA+ S QQ
Sbjct: 505 -GSTKP-PPQQPGPAKPSPQQ 523



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 37/139 (26%), Positives = 44/139 (31%), Gaps = 35/139 (25%)

Query: 212 GSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKH 271
           G G I +              P KP S     +KP  QQP         G + PPP    
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP---------GPAKPPP---- 491

Query: 272 NMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPP 331
                    +   AK PSQ       QP  GS +P  QQ   + P  Q     Q     P
Sbjct: 492 --------QQPGSAKPPSQ-------QP--GSTKPPPQQPGPAKPSPQ-----QPGSTKP 529

Query: 332 PPPQPAQLSVQQQAAQPTR 350
           P  QP       Q   P +
Sbjct: 530 PSQQPGSAKPSAQQPSPAK 548



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 15/39 (38%), Positives = 17/39 (43%)

Query: 298  QPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQP 336
            Q   GSP      A   P    +S+    QP PPPPP P
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP 2413


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 39/151 (25%), Positives = 51/151 (33%), Gaps = 17/151 (11%)

Query: 205 KVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQP-KLKTKNGIAGSS 263
           K+     G G  ++        P     P KP       +KP  QQP   K  +   GS+
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 264 LPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVG 323
            PPP              GP   +P Q           GS +P  QQ + + P AQ S  
Sbjct: 508 KPPP-----------QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556

Query: 324 QQTQ-----PLPPPPPQPAQLSVQQQAAQPT 349
             +Q     PL PP   P+      Q    T
Sbjct: 557 PVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 51/185 (27%), Positives = 68/185 (36%), Gaps = 26/185 (14%)

Query: 218 SNIVASNSLPPATIAPPKPASWADIASKPAKQQP-KLKTKNGIAGSSLPPPPIKHNMDIG 276
           ++IV   S+ P+  +P KP        KP  QQP   K++ G A     P  +   +   
Sbjct: 286 ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ 345

Query: 277 TWDNKGPV-----AKAPSQAL------VQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQ 325
               K PV      K P+Q L       Q  G     S QP G +A   PP    +  QQ
Sbjct: 346 PGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP-GPKALAQPPGVGKTPAQQ 404

Query: 326 TQPLPPPPPQ---PAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQ---SQAGSG 379
             P  PP  Q   P  L+ Q     P +   P           V   G G+    QAG G
Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK-------TPVQQPGPGKIPAQQAGPG 457

Query: 380 STPSE 384
            T ++
Sbjct: 458 KTSAQ 462



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 36/119 (30%), Positives = 48/119 (40%), Gaps = 22/119 (18%)

Query: 235 KPASWADIASKPAKQQPKLK-----TKNGIAGSSLPPPPIKHNMDIGTWD--NKGPVAKA 287
           K A   D+A  P+  QPKLK     T + ++ SS  P       D       +K P  K 
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702

Query: 288 PSQALVQNIGQPT-QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQA 345
           P       + QPT  GSP    +Q    PP A       +   P PP +P+  S Q +A
Sbjct: 703 PPPL----VKQPTLHGSPSAKAKQ----PPEA------DSLSKPAPPKEPSVPSEQDKA 747



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 6/141 (4%)

Query: 204 PKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSS 263
           PK +    G G   +        P   +  PKP +       PAK     KT     G  
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447

Query: 264 LPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSP-QPVGQQANNSPPVAQASV 322
             P   +      +    GP  K PSQ        P Q  P +P  QQ  ++ P +Q   
Sbjct: 448 KIPAQ-QAGPGKTSAQQTGP-TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP- 504

Query: 323 GQQTQPLPPPPPQPAQLSVQQ 343
              T+P PP  P PA+ S QQ
Sbjct: 505 -GSTKP-PPQQPGPAKPSPQQ 523



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 37/139 (26%), Positives = 44/139 (31%), Gaps = 35/139 (25%)

Query: 212 GSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKH 271
           G G I +              P KP S     +KP  QQP         G + PPP    
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP---------GPAKPPP---- 491

Query: 272 NMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPP 331
                    +   AK PSQ       QP  GS +P  QQ   + P  Q     Q     P
Sbjct: 492 --------QQPGSAKPPSQ-------QP--GSTKPPPQQPGPAKPSPQ-----QPGSTKP 529

Query: 332 PPPQPAQLSVQQQAAQPTR 350
           P  QP       Q   P +
Sbjct: 530 PSQQPGSAKPSAQQPSPAK 548



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 15/39 (38%), Positives = 17/39 (43%)

Query: 298  QPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQP 336
            Q   GSP      A   P    +S+    QP PPPPP P
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP 2413


>gi|40807465 zinc finger protein 341 [Homo sapiens]
          Length = 847

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 56/237 (23%), Positives = 90/237 (37%), Gaps = 20/237 (8%)

Query: 163 AMIDGQSAFANET---LNKAPGMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSN 219
           +++DGQ A  + T   +N  P +  +D     L     +  +++P  +          + 
Sbjct: 22  SLLDGQGAVPDPTGQSVNAPPAIQPLDDEDVFLCGKCKKQFNSLPAFMTHKREQCQGNAP 81

Query: 220 IVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWD 279
            +A+ SL   +I PP  A  A       +Q P    +      ++PP P+   +  G   
Sbjct: 82  ALATVSLATNSIYPPSAAPTA------VQQAPTPANRQISTYITVPPSPLIQTLVQGNIL 135

Query: 280 NKGPVAKAPSQALVQNIGQPTQGSPQPVGQQAN-NSPPVAQASVGQQTQPLPPPPPQPAQ 338
               V  +   A   ++ QP    P PV    N +S P    S   Q  P PPPPP    
Sbjct: 136 VSDDVLMSAMSAFT-SLDQPMPQGPPPVQSSLNMHSVP----SYLTQPPPPPPPPPPLPP 190

Query: 339 LSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTP-----SEPHPVLE 390
               Q    P + + P  R +  G+  V+        AGSG+        +P+P LE
Sbjct: 191 PPPPQPPPPPPQSLGPPGRPNPGGNGVVEVYSAAAPLAGSGTVEIQALGMQPYPPLE 247


>gi|169163728 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 237

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 45/152 (29%), Positives = 62/152 (40%), Gaps = 29/152 (19%)

Query: 260 AGSSLPPPPIKHNMDIGTWDN--KGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPP- 316
           AG S PP P+      GTW    +GP A +P+ AL      P +   + V  +A   PP 
Sbjct: 31  AGYSRPPSPVGRARRRGTWLRVLRGPRAPSPAPALPARARPPRENRKRAVPARAARGPPK 90

Query: 317 ---------VAQASVGQQTQPLPP--PPPQP--------AQLSVQQQAAQPTRWVAPRN- 356
                    V  AS  +++QP  P  PPP P         + S+ + A   TR    R+ 
Sbjct: 91  RPAGGQTGGVEAASGEERSQPRRPRRPPPAPRRPRPAPGRRKSLYEAAPLLTREKGGRSG 150

Query: 357 -----RGSGFGH-NGVDGNGVGQSQAGSGSTP 382
                 GSG+ H +     G G S AG  + P
Sbjct: 151 RRGDRGGSGWSHGHTARVGGTGDSSAGLTTFP 182


>gi|169163708 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 237

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 45/152 (29%), Positives = 62/152 (40%), Gaps = 29/152 (19%)

Query: 260 AGSSLPPPPIKHNMDIGTWDN--KGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPP- 316
           AG S PP P+      GTW    +GP A +P+ AL      P +   + V  +A   PP 
Sbjct: 31  AGYSRPPSPVGRARRRGTWLRVLRGPRAPSPAPALPARARPPRENRKRAVPARAARGPPK 90

Query: 317 ---------VAQASVGQQTQPLPP--PPPQP--------AQLSVQQQAAQPTRWVAPRN- 356
                    V  AS  +++QP  P  PPP P         + S+ + A   TR    R+ 
Sbjct: 91  RPAGGQTGGVEAASGEERSQPRRPRRPPPAPRRPRPAPGRRKSLYEAAPLLTREKGGRSG 150

Query: 357 -----RGSGFGH-NGVDGNGVGQSQAGSGSTP 382
                 GSG+ H +     G G S AG  + P
Sbjct: 151 RRGDRGGSGWSHGHTARVGGTGDSSAGLTTFP 182


>gi|169163019 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 237

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 40/152 (26%), Positives = 59/152 (38%), Gaps = 29/152 (19%)

Query: 260 AGSSLPPPPIKHNMDIGTWDN--KGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPP- 316
           AG S PP P+      GTW    +GP A +P+ AL      P +   + V  +A   PP 
Sbjct: 31  AGYSRPPSPVGRARRRGTWLRVLRGPRAPSPAPALPARARPPRENRKRAVPARAARGPPK 90

Query: 317 ---------VAQASVGQQTQPL-----PPPPPQPAQLSVQQQAAQPTRWVAPRNRGSGFG 362
                    V  AS  +++QP      PP P +P     ++++      +  R +G   G
Sbjct: 91  RPAGGQTGGVEAASGEERSQPRRPRRPPPAPRRPRPAPGRRKSLYEAAPLLTREKGGRSG 150

Query: 363 HNGVDGN------------GVGQSQAGSGSTP 382
             G  G+            G G S AG  + P
Sbjct: 151 RRGDRGDSGWSHGHTARVGGTGDSSAGLTTFP 182


>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2790

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 28/115 (24%)

Query: 225  SLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPV 284
            SLP AT  PP     A++A +  ++ P  K  N  AG S PP P+ +             
Sbjct: 1606 SLPAATPPPPPQPPKAELAEREWERPPMAKEGNE-AGPSSPPDPLPNE-----------A 1653

Query: 285  AKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQL 339
            A+  ++AL++N G                   V Q + G+Q  P PP PP P  L
Sbjct: 1654 ARTAAKALLENFGFEL----------------VIQYNEGKQAVPPPPTPPPPEAL 1692



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 38/155 (24%), Positives = 59/155 (38%), Gaps = 27/155 (17%)

Query: 194  LGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKL 253
            L S +  + + + V + + S S   ++  +   PPA  APP        AS P    P L
Sbjct: 2383 LFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTP----ASMPLGAAPTL 2438

Query: 254  KTKNGI--AGSSLPPPPIKHNMDIGTWDNKGPVAKA----------PSQALVQNIGQPTQ 301
                 +  +G +L  PP+ +        N GP A +          P+  +VQ  G    
Sbjct: 2439 PRLAPVLLSGPALAQPPLGNLAPF----NSGPAASSGLLGLATSVLPTTTVVQTAGPGRP 2494

Query: 302  GSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQP 336
               +P+  Q N S           T P+P PP +P
Sbjct: 2495 LPQRPMPDQTNTS-------TAGTTDPVPGPPTEP 2522


>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 28/115 (24%)

Query: 225  SLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPV 284
            SLP AT  PP     A++A +  ++ P  K  N  AG S PP P+ +             
Sbjct: 1522 SLPAATPPPPPQPPKAELAEREWERPPMAKEGNE-AGPSSPPDPLPNE-----------A 1569

Query: 285  AKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQL 339
            A+  ++AL++N G                   V Q + G+Q  P PP PP P  L
Sbjct: 1570 ARTAAKALLENFGFEL----------------VIQYNEGKQAVPPPPTPPPPEAL 1608



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 38/155 (24%), Positives = 59/155 (38%), Gaps = 27/155 (17%)

Query: 194  LGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKL 253
            L S +  + + + V + + S S   ++  +   PPA  APP        AS P    P L
Sbjct: 2299 LFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTP----ASMPLGAAPTL 2354

Query: 254  KTKNGI--AGSSLPPPPIKHNMDIGTWDNKGPVAKA----------PSQALVQNIGQPTQ 301
                 +  +G +L  PP+ +        N GP A +          P+  +VQ  G    
Sbjct: 2355 PRLAPVLLSGPALAQPPLGNLAPF----NSGPAASSGLLGLATSVLPTTTVVQTAGPGRP 2410

Query: 302  GSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQP 336
               +P+  Q N S           T P+P PP +P
Sbjct: 2411 LPQRPMPDQTNTS-------TAGTTDPVPGPPTEP 2438


>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 28/115 (24%)

Query: 225  SLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPV 284
            SLP AT  PP     A++A +  ++ P  K  N  AG S PP P+ +             
Sbjct: 1522 SLPAATPPPPPQPPKAELAEREWERPPMAKEGNE-AGPSSPPDPLPNE-----------A 1569

Query: 285  AKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQL 339
            A+  ++AL++N G                   V Q + G+Q  P PP PP P  L
Sbjct: 1570 ARTAAKALLENFGFEL----------------VIQYNEGKQAVPPPPTPPPPEAL 1608



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 38/155 (24%), Positives = 59/155 (38%), Gaps = 27/155 (17%)

Query: 194  LGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKL 253
            L S +  + + + V + + S S   ++  +   PPA  APP        AS P    P L
Sbjct: 2299 LFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTP----ASMPLGAAPTL 2354

Query: 254  KTKNGI--AGSSLPPPPIKHNMDIGTWDNKGPVAKA----------PSQALVQNIGQPTQ 301
                 +  +G +L  PP+ +        N GP A +          P+  +VQ  G    
Sbjct: 2355 PRLAPVLLSGPALAQPPLGNLAPF----NSGPAASSGLLGLATSVLPTTTVVQTAGPGRP 2410

Query: 302  GSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQP 336
               +P+  Q N S           T P+P PP +P
Sbjct: 2411 LPQRPMPDQTNTS-------TAGTTDPVPGPPTEP 2438


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/128 (31%), Positives = 47/128 (36%), Gaps = 20/128 (15%)

Query: 229 ATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAP 288
           A   PPKPA     A  PA  Q  L          LP PP+     +   D + P     
Sbjct: 877 AAALPPKPAR--PPAVSPALTQTPL----------LPQPPMAQPPQVLLEDEEPPAPPLT 924

Query: 289 SQAL------VQNIGQPTQGSP--QPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLS 340
           S  +      +Q +  PT   P  +   Q     PP    SV QQ Q  PPPPP P    
Sbjct: 925 SMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP 984

Query: 341 VQQQAAQP 348
             QQ  QP
Sbjct: 985 PPQQQHQP 992



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 35/133 (26%), Positives = 49/133 (36%), Gaps = 19/133 (14%)

Query: 227 PPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDI-------GTWD 279
           PP    PP P         P    P +  +   A  S PPP I   + +         +D
Sbjct: 759 PPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFD 818

Query: 280 NKG----PVAKAPSQALVQNIGQPTQGSPQP-VGQQANNSPPVAQASVGQQ-------TQ 327
             G    P+   P   L  ++ QP + S  P + Q A  SPP    ++ QQ         
Sbjct: 819 PIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAA 878

Query: 328 PLPPPPPQPAQLS 340
            LPP P +P  +S
Sbjct: 879 ALPPKPARPPAVS 891



 Score = 36.6 bits (83), Expect = 0.065
 Identities = 35/112 (31%), Positives = 42/112 (37%), Gaps = 31/112 (27%)

Query: 227  PPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAK 286
            PP    PP P+    +  +P    P             PPP  +H           PV  
Sbjct: 955  PPPLPPPPHPSVQQQLQQQPPPPPPP---------QPQPPPQQQHQPP------PRPVHL 999

Query: 287  APSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQ 338
             P Q    +I QP    P P GQQ  + PP      GQQ     PPPPQPA+
Sbjct: 1000 QPMQ-FSTHIQQP----PPPQGQQPPHPPP------GQQ-----PPPPQPAK 1035



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 4/61 (6%)

Query: 293 VQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWV 352
           +Q    P    P P  QQ    PP  Q    QQ  P PPPPP   Q +     + P  ++
Sbjct: 746 MQQAPAPVPQQPPPPPQQPPPPPPPQQ----QQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801

Query: 353 A 353
           A
Sbjct: 802 A 802



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 4/55 (7%)

Query: 298 QPTQGSPQPVGQQA----NNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQP 348
           Q  Q +P PV QQ        PP       QQ  P PPPP  P Q +   +++ P
Sbjct: 744 QQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP 798



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 30/103 (29%), Positives = 35/103 (33%), Gaps = 13/103 (12%)

Query: 248  KQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPV 307
            K QP       +   S PPPP+             P   +  Q L Q    P    PQP 
Sbjct: 937  KVQPPTPLLPSVKVQSQPPPPLPP-----------PPHPSVQQQLQQQPPPPPPPQPQPP 985

Query: 308  GQQANNSPP--VAQASVGQQTQPLPPPPPQPAQLSVQQQAAQP 348
             QQ +  PP  V    +   T    PPPPQ  Q        QP
Sbjct: 986  PQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQP 1028


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 53/213 (24%), Positives = 75/213 (35%), Gaps = 47/213 (22%)

Query: 227 PPATIAPPKPASWADIASKPAKQQPKLKTKNGI------AGSSLPP-------------- 266
           PP    PP+P         P +Q+P  + +  +      AGS LP               
Sbjct: 461 PPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPAS 520

Query: 267 ---PPI----KHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQ-----PVGQQANNS 314
              PP     + +  +       P A+ P+    Q    P Q + Q     P   +A+ +
Sbjct: 521 QAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGA 580

Query: 315 PPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAP----RNRGSGFGHNGVDGNG 370
           PP      GQQ Q  P  PP PA  + Q   A P     P    + R SG G  G     
Sbjct: 581 PPG-----GQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ 635

Query: 371 VGQSQAGSGSTPS------EPHPVLEKLRSINN 397
           + Q  +     P+       PHP L K +S+ N
Sbjct: 636 LAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTN 668



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 39/151 (25%), Positives = 53/151 (35%), Gaps = 33/151 (21%)

Query: 212 GSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQ--PKLKTKNGIAGSSLPPPPI 269
           G G  +  +      PPA   P  P+        P +Q   P+   +  ++G   P PP 
Sbjct: 528 GQGRQSRPVAGGPGAPPAARPPASPS--------PQRQAGPPQATRQTSVSG---PAPPK 576

Query: 270 KHNMDIGTWDNKGPVAKAPSQA----------LVQNIGQPTQGSPQPVGQQANNSPPVAQ 319
                 G    +GP  K P  A           V   G PT   P+P G      P    
Sbjct: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQL 636

Query: 320 ASVGQQTQPLPPP-------PPQPAQLSVQQ 343
           A   + +Q +PPP       PP P QL+  Q
Sbjct: 637 AQ--KPSQDVPPPATAAAGGPPHP-QLNKSQ 664



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 30/109 (27%), Positives = 38/109 (34%), Gaps = 9/109 (8%)

Query: 285 AKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPL-----PPPPPQPAQL 339
           ++ P+    Q    P  G PQP        PP+ Q    Q  Q L     P   P P +L
Sbjct: 449 SQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRL 508

Query: 340 -SVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEPHP 387
            S      QP    AP  +G G     V G   G     +   P+ P P
Sbjct: 509 PSPTSAPQQPASQAAPPTQGQGRQSRPVAG---GPGAPPAARPPASPSP 554


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/170 (23%), Positives = 64/170 (37%), Gaps = 29/170 (17%)

Query: 200 ASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGI 259
           A  +   V   + S  + S  V + +  PA    P PA    +AS   K++ +       
Sbjct: 483 AVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTE------- 535

Query: 260 AGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANN-SPPVA 318
             S +PP P    +     +   PV     +       +PT   PQ  G +++  +PP+ 
Sbjct: 536 --SEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLP 593

Query: 319 QAS-------------VGQQTQ------PLPPPPPQPAQLSVQQQAAQPT 349
             S             VG   +      PLPP PPQPA+   ++  A P+
Sbjct: 594 PGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPS 643



 Score = 30.4 bits (67), Expect = 4.7
 Identities = 34/151 (22%), Positives = 55/151 (36%), Gaps = 14/151 (9%)

Query: 207 VGSAVGSGSITSNIVASNSLPPATIAPPKPAS----WADIASKPAKQQPKLKTKNGIAGS 262
           + SA       S +    + P  T +PP+ A+     A    +PA  +P +         
Sbjct: 525 LASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSGSR 584

Query: 263 SLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT------QGSPQPVGQQANNSPP 316
           S PP P    +  G+     P A  P + +  ++  PT         PQP  +Q+  SP 
Sbjct: 585 SSPPAP---PLPPGSGSPGTPQA-LPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPA 640

Query: 317 VAQASVGQQTQPLPPPPPQPAQLSVQQQAAQ 347
               +      P P     PAQ+ +    A+
Sbjct: 641 SPSPASPGPASPSPVSLSNPAQVDLGAATAE 671



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 32/133 (24%), Positives = 45/133 (33%), Gaps = 27/133 (20%)

Query: 220 IVASNSLPPATIAPPKPASWADIASKPAKQQ--PKLKTKNGIAGSSLPPP-PIKHNMDIG 276
           +  S S PPA   PP   S       P   Q  P+    + +   ++PPP P        
Sbjct: 580 VSGSRSSPPAPPLPPGSGS-------PGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPAR 632

Query: 277 TWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQ---------ANNSPPVAQASVGQQTQ 327
               + P + +P+         P   SP PV            A       +A  G  T 
Sbjct: 633 RQSRRSPASPSPAS--------PGPASPSPVSLSNPAQVDLGAATAEGGAPEAISGVPTP 684

Query: 328 PLPPPPPQPAQLS 340
           P  PP P+P  L+
Sbjct: 685 PAIPPQPRPRSLA 697


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 38/132 (28%), Positives = 47/132 (35%), Gaps = 19/132 (14%)

Query: 256 KNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSP 315
           + G+     PPP       +G   N+GP+   P Q+       P    P P   Q    P
Sbjct: 25  RGGLHDFRSPPP------GMGLNQNRGPMGPGPGQS------GPKPPIPPPPPHQQQQQP 72

Query: 316 PVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQ 375
           P  Q    Q     PPP PQP Q   QQQ   P +  +      G G       GVG + 
Sbjct: 73  PPQQPPPQQPPPHQPPPHPQPHQ---QQQPPPPPQDSSKPVVAQGPG----PAPGVGSAP 125

Query: 376 AGSGSTPSEPHP 387
             S S P    P
Sbjct: 126 PASSSAPPATPP 137



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 42/172 (24%), Positives = 52/172 (30%), Gaps = 14/172 (8%)

Query: 223 SNSLPPATIAPPKPASWADIASKPAKQQP---KLKTKNGIAGSSLPPPPIKHNMDIGTWD 279
           S   PP    PP          +P  QQP   +            PPPP + +       
Sbjct: 54  SGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQ 113

Query: 280 NKGPV----AKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQ 335
             GP     +  P+ +       PT G+P   G     +PP A  S      P   PPP 
Sbjct: 114 GPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSA-----PPGAPPPT 168

Query: 336 PAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEPHP 387
           P    V     Q      P     G G     G G G  +   G  P  P P
Sbjct: 169 PPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPK--GGKMPGGPKP 218


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 37/138 (26%), Positives = 51/138 (36%), Gaps = 21/138 (15%)

Query: 200  ASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGI 259
            A+  P V G AV   S+     A +  PP ++ P +    A   + P +QQP    + G 
Sbjct: 977  AAGPPAVHGLAVAPASVVP-APAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGA 1035

Query: 260  AGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPVAQ 319
                +PPP              GP   +P         Q T  S  P     +  P VA 
Sbjct: 1036 VPPGVPPP--------------GPHGPSPFP------NQQTPPSMMPGAVPGSGHPGVAG 1075

Query: 320  ASVGQQTQPLPPPPPQPA 337
             +       +PPPPP PA
Sbjct: 1076 NAPLGLPFGMPPPPPPPA 1093


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/139 (30%), Positives = 57/139 (41%), Gaps = 17/139 (12%)

Query: 208 GSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQ----QPKLKTKNGIAGSS 263
           GS VGSGS   ++V S  L      PP P     I  KP        P    ++G AG  
Sbjct: 600 GSDVGSGS--GDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEP 657

Query: 264 LPP-PPIKHNMD-----IGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNSPPV 317
            PP P  +  +D      G    KG  A+ P+ ++ +      +G P P G++    PP 
Sbjct: 658 GPPGPEGQPGVDGATGLPGMKGEKG--ARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPP- 714

Query: 318 AQASVGQQTQPLPPPPPQP 336
               +G    P PP PP P
Sbjct: 715 --GVMGPPGPPGPPGPPGP 731


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,028,021
Number of Sequences: 37866
Number of extensions: 1552859
Number of successful extensions: 12095
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 130
Number of HSP's successfully gapped in prelim test: 600
Number of HSP's that attempted gapping in prelim test: 8582
Number of HSP's gapped (non-prelim): 2886
length of query: 579
length of database: 18,247,518
effective HSP length: 108
effective length of query: 471
effective length of database: 14,157,990
effective search space: 6668413290
effective search space used: 6668413290
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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