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Search of human proteins with 239745040
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239745040 PREDICTED: ankyrin repeat domain-containing
protein ENSP00000383090-like [Homo sapiens]
(270 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756223 PREDICTED: ankyrin repeat domain-containing protein... 553 e-158
gi|239745040 PREDICTED: ankyrin repeat domain-containing protein... 553 e-158
gi|169209369 PREDICTED: similar to Putative ankyrin repeat domai... 377 e-105
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 277 8e-75
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 268 5e-72
gi|239757617 PREDICTED: similar to hCG1793014 [Homo sapiens] 249 2e-66
gi|239744894 PREDICTED: similar to Putative ankyrin repeat domai... 248 3e-66
gi|239756067 PREDICTED: similar to Putative ankyrin repeat domai... 245 3e-65
gi|169194585 PREDICTED: similar to hCG1793014 [Homo sapiens] 205 3e-53
gi|169201955 PREDICTED: similar to hCG1793014 [Homo sapiens] 205 3e-53
gi|169192125 PREDICTED: similar to UNCoordinated family member (... 200 1e-51
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 189 3e-48
gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo... 169 2e-42
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 161 5e-40
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 160 1e-39
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 160 1e-39
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 159 2e-39
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 157 1e-38
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 157 1e-38
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 157 1e-38
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 154 8e-38
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 154 8e-38
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 154 8e-38
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 154 8e-38
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 154 1e-37
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 151 5e-37
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 150 1e-36
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 150 1e-36
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 150 1e-36
gi|224282147 prostate-specific P704P [Homo sapiens] 150 1e-36
>gi|239756223 PREDICTED: ankyrin repeat domain-containing protein
ENSP00000383090-like [Homo sapiens]
Length = 270
Score = 553 bits (1426), Expect = e-158
Identities = 270/270 (100%), Positives = 270/270 (100%)
Query: 1 MDPLLPILCCEQGTLVRCYNMWDFMPVDQEFWKPQKSGPGSGSVNRIAKPSPGIRIYPSE 60
MDPLLPILCCEQGTLVRCYNMWDFMPVDQEFWKPQKSGPGSGSVNRIAKPSPGIRIYPSE
Sbjct: 1 MDPLLPILCCEQGTLVRCYNMWDFMPVDQEFWKPQKSGPGSGSVNRIAKPSPGIRIYPSE 60
Query: 61 DEKVVIQGQKTCHIRVSLLMYAVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTP 120
DEKVVIQGQKTCHIRVSLLMYAVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTP
Sbjct: 61 DEKVVIQGQKTCHIRVSLLMYAVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTP 120
Query: 121 LMKAAQCQREVCANILIDSGADPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKN 180
LMKAAQCQREVCANILIDSGADPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKN
Sbjct: 121 LMKAAQCQREVCANILIDSGADPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKN 180
Query: 181 KAGHTPLLLAIRKRSEQIVEFLLTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEG 240
KAGHTPLLLAIRKRSEQIVEFLLTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEG
Sbjct: 181 KAGHTPLLLAIRKRSEQIVEFLLTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEG 240
Query: 241 TSEGTPDEAAPLVERTPDMAESLVERTPDE 270
TSEGTPDEAAPLVERTPDMAESLVERTPDE
Sbjct: 241 TSEGTPDEAAPLVERTPDMAESLVERTPDE 270
>gi|239745040 PREDICTED: ankyrin repeat domain-containing protein
ENSP00000383090-like [Homo sapiens]
Length = 270
Score = 553 bits (1426), Expect = e-158
Identities = 270/270 (100%), Positives = 270/270 (100%)
Query: 1 MDPLLPILCCEQGTLVRCYNMWDFMPVDQEFWKPQKSGPGSGSVNRIAKPSPGIRIYPSE 60
MDPLLPILCCEQGTLVRCYNMWDFMPVDQEFWKPQKSGPGSGSVNRIAKPSPGIRIYPSE
Sbjct: 1 MDPLLPILCCEQGTLVRCYNMWDFMPVDQEFWKPQKSGPGSGSVNRIAKPSPGIRIYPSE 60
Query: 61 DEKVVIQGQKTCHIRVSLLMYAVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTP 120
DEKVVIQGQKTCHIRVSLLMYAVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTP
Sbjct: 61 DEKVVIQGQKTCHIRVSLLMYAVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTP 120
Query: 121 LMKAAQCQREVCANILIDSGADPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKN 180
LMKAAQCQREVCANILIDSGADPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKN
Sbjct: 121 LMKAAQCQREVCANILIDSGADPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKN 180
Query: 181 KAGHTPLLLAIRKRSEQIVEFLLTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEG 240
KAGHTPLLLAIRKRSEQIVEFLLTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEG
Sbjct: 181 KAGHTPLLLAIRKRSEQIVEFLLTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEG 240
Query: 241 TSEGTPDEAAPLVERTPDMAESLVERTPDE 270
TSEGTPDEAAPLVERTPDMAESLVERTPDE
Sbjct: 241 TSEGTPDEAAPLVERTPDMAESLVERTPDE 270
>gi|169209369 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383090 [Homo sapiens]
Length = 193
Score = 377 bits (969), Expect = e-105
Identities = 187/193 (96%), Positives = 189/193 (97%)
Query: 78 LLMYAVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILI 137
+L Y +TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILI
Sbjct: 1 MLSYKHAETALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILI 60
Query: 138 DSGADPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQ 197
DSGADPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQ
Sbjct: 61 DSGADPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQ 120
Query: 198 IVEFLLTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTP 257
IVEFLLTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTP
Sbjct: 121 IVEFLLTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTP 180
Query: 258 DMAESLVERTPDE 270
DMAESLVERTPDE
Sbjct: 181 DMAESLVERTPDE 193
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 277 bits (708), Expect = 8e-75
Identities = 147/235 (62%), Positives = 165/235 (70%), Gaps = 46/235 (19%)
Query: 82 AVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGA 141
A ++TALHW C NGH EVVT LVDRKCQLD+LDGE+RTPLMKA QC +E CANILIDSGA
Sbjct: 15 AQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILIDSGA 74
Query: 142 DPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEF 201
D N+VDVYGNTA+HYA+Y E LSVVAKLLS GA IEV NKA TPLLL+I KRSEQIVEF
Sbjct: 75 DINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIVEF 134
Query: 202 LLTKNTNANAVDKFKC-------------------------------------------- 217
LL KN NANAV+K+KC
Sbjct: 135 LLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGF 194
Query: 218 --IHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270
IH+Q++EY +K+SKN QN+NPEGTS GTPDEAAPL ERTPD AESLVE+TPDE
Sbjct: 195 HHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDE 249
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 268 bits (684), Expect = 5e-72
Identities = 142/233 (60%), Positives = 162/233 (69%), Gaps = 46/233 (19%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++TALHW C NGHAEVVT LVDRKCQL++LDGE RTPLMKA QC+RE CANILID+GAD
Sbjct: 73 KRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAGADL 132
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
N VDVYGNTA+HYA+Y ENL +VA LLS GA IEV+NKA TPLLLAI+KRS+Q VEFLL
Sbjct: 133 NYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLL 192
Query: 204 TKNTNANAVDKFKC---------------------------------------------- 217
TKN NANA ++ KC
Sbjct: 193 TKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNY 252
Query: 218 IHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270
IHQQLLE+ +K+ KN QN+NPEGTS GTPDEAAPL ERTPD AESL+E+TPDE
Sbjct: 253 IHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLEKTPDE 305
Score = 34.3 bits (77), Expect = 0.12
Identities = 19/69 (27%), Positives = 32/69 (46%)
Query: 147 DVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKN 206
D+ TA+H+A + VV L+ + V + G TPL+ A++ E L+
Sbjct: 70 DMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDAG 129
Query: 207 TNANAVDKF 215
+ N VD +
Sbjct: 130 ADLNYVDVY 138
>gi|239757617 PREDICTED: similar to hCG1793014 [Homo sapiens]
Length = 251
Score = 249 bits (636), Expect = 2e-66
Identities = 123/136 (90%), Positives = 126/136 (92%)
Query: 82 AVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGA 141
A ++TALHW CANG AEVVT LVDRKCQLDILDGENRT LMKA QCQREVCANILIDSGA
Sbjct: 70 AKKRTALHWACANGRAEVVTLLVDRKCQLDILDGENRTTLMKAVQCQREVCANILIDSGA 129
Query: 142 DPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEF 201
DPNIVDVYGNTAVHYAL GENLSVVAKLLSCGADIEVKNK GHTPLLL +RKRSEQIVEF
Sbjct: 130 DPNIVDVYGNTAVHYALIGENLSVVAKLLSCGADIEVKNKTGHTPLLLVMRKRSEQIVEF 189
Query: 202 LLTKNTNANAVDKFKC 217
LLTKN NANAVDKFKC
Sbjct: 190 LLTKNANANAVDKFKC 205
Score = 37.0 bits (84), Expect = 0.018
Identities = 22/91 (24%), Positives = 41/91 (45%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TA+H+ + VV L+ +++ + TPL+ + + E L+ A+ N
Sbjct: 140 TAVHYALIGENLSVVAKLLSCGADIEVKNKTGHTPLLLVMRKRSEQIVEFLLTKNANANA 199
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADI 176
VD + TA+ A+ + +V +L DI
Sbjct: 200 VDKFKCTALMLAMCHGSSEIVGMVLQENVDI 230
>gi|239744894 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383069 [Homo sapiens]
Length = 197
Score = 248 bits (634), Expect = 3e-66
Identities = 124/138 (89%), Positives = 129/138 (93%), Gaps = 2/138 (1%)
Query: 82 AVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGA 141
A ++TALHW CANGHAEVVT LVDRKCQLD+LDGEN TPLMKA QCQREVCANILIDSGA
Sbjct: 14 AKKRTALHWACANGHAEVVTLLVDRKCQLDVLDGENGTPLMKAVQCQREVCANILIDSGA 73
Query: 142 DPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEF 201
DPNIVDVY NTAVHYA+YGENLSVVAKLLSCGADI+VKNKAGHTPLLLAIRKRSEQIVEF
Sbjct: 74 DPNIVDVYVNTAVHYAVYGENLSVVAKLLSCGADIKVKNKAGHTPLLLAIRKRSEQIVEF 133
Query: 202 LLTKNTNANA--VDKFKC 217
LLTKN NANA VDKFKC
Sbjct: 134 LLTKNANANANSVDKFKC 151
>gi|239756067 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383069 [Homo sapiens]
Length = 157
Score = 245 bits (625), Expect = 3e-65
Identities = 123/137 (89%), Positives = 128/137 (93%), Gaps = 2/137 (1%)
Query: 82 AVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGA 141
A ++TALHW CANGHAEVVT LVDRKCQLD+LDGEN TPLMKA QCQREVCANILIDSGA
Sbjct: 14 AKKRTALHWACANGHAEVVTLLVDRKCQLDVLDGENGTPLMKAVQCQREVCANILIDSGA 73
Query: 142 DPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEF 201
DPNIVDVY NTAVHYA+YGENLSVVAKLLSCGADI+VKNKAGHTPLLLAIRKRSEQIVEF
Sbjct: 74 DPNIVDVYVNTAVHYAVYGENLSVVAKLLSCGADIKVKNKAGHTPLLLAIRKRSEQIVEF 133
Query: 202 LLTKNTNANA--VDKFK 216
LLTKN NANA VDKFK
Sbjct: 134 LLTKNANANANSVDKFK 150
>gi|169194585 PREDICTED: similar to hCG1793014 [Homo sapiens]
Length = 366
Score = 205 bits (522), Expect = 3e-53
Identities = 101/132 (76%), Positives = 110/132 (83%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH C N H EV+T L DRKC+LD+ D ENRTPLMKA QC RE CANIL+DSG PNI
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREACANILVDSGPSPNI 86
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VDVYGN A+HYA+Y ENLSVVAKLLS GADIEVKNKA TPLLL I KRSE+IVEFL+TK
Sbjct: 87 VDVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTK 146
Query: 206 NTNANAVDKFKC 217
N +ANAVDKFKC
Sbjct: 147 NASANAVDKFKC 158
Score = 39.3 bits (90), Expect = 0.004
Identities = 29/108 (26%), Positives = 48/108 (44%)
Query: 87 ALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNIV 146
ALH+ + + VV L+ R +++ + TPL+ + E L+ A N V
Sbjct: 94 ALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTKNASANAV 153
Query: 147 DVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKR 194
D + TA+ A+ +L V+ LL DI ++ G T A+ R
Sbjct: 154 DKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASR 201
Score = 32.0 bits (71), Expect = 0.58
Identities = 18/79 (22%), Positives = 35/79 (44%)
Query: 152 TAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKNTNANA 211
TA+H A ++ V+ L ++V++ TPL+ A++ E L+ + N
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREACANILVDSGPSPNI 86
Query: 212 VDKFKCIHQQLLEYKQKIS 230
VD + + Y + +S
Sbjct: 87 VDVYGNMALHYAVYSENLS 105
>gi|169201955 PREDICTED: similar to hCG1793014 [Homo sapiens]
Length = 366
Score = 205 bits (522), Expect = 3e-53
Identities = 101/132 (76%), Positives = 110/132 (83%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH C N H EV+T L DRKC+LD+ D ENRTPLMKA QC RE CANIL+DSG PNI
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREACANILVDSGPSPNI 86
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VDVYGN A+HYA+Y ENLSVVAKLLS GADIEVKNKA TPLLL I KRSE+IVEFL+TK
Sbjct: 87 VDVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTK 146
Query: 206 NTNANAVDKFKC 217
N +ANAVDKFKC
Sbjct: 147 NASANAVDKFKC 158
Score = 39.3 bits (90), Expect = 0.004
Identities = 29/108 (26%), Positives = 48/108 (44%)
Query: 87 ALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNIV 146
ALH+ + + VV L+ R +++ + TPL+ + E L+ A N V
Sbjct: 94 ALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTKNASANAV 153
Query: 147 DVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKR 194
D + TA+ A+ +L V+ LL DI ++ G T A+ R
Sbjct: 154 DKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASR 201
Score = 32.0 bits (71), Expect = 0.58
Identities = 18/79 (22%), Positives = 35/79 (44%)
Query: 152 TAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKNTNANA 211
TA+H A ++ V+ L ++V++ TPL+ A++ E L+ + N
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREACANILVDSGPSPNI 86
Query: 212 VDKFKCIHQQLLEYKQKIS 230
VD + + Y + +S
Sbjct: 87 VDVYGNMALHYAVYSENLS 105
>gi|169192125 PREDICTED: similar to UNCoordinated family member
(unc-44) [Homo sapiens]
Length = 393
Score = 200 bits (508), Expect = 1e-51
Identities = 99/132 (75%), Positives = 109/132 (82%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH C N H EV+T L DRKC+LD+ D ENRTPLMKA QC RE ANIL+DSG PNI
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREAYANILVDSGPSPNI 86
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VDVYGN A+HYA+Y ENLSVVAKLLS GADI+VKNKA TPLLL I KRSE+IVEFL+TK
Sbjct: 87 VDVYGNMALHYAVYSENLSVVAKLLSRGADIQVKNKACLTPLLLVITKRSEEIVEFLVTK 146
Query: 206 NTNANAVDKFKC 217
N +ANAVDKFKC
Sbjct: 147 NASANAVDKFKC 158
Score = 38.5 bits (88), Expect = 0.006
Identities = 29/108 (26%), Positives = 47/108 (43%)
Query: 87 ALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNIV 146
ALH+ + + VV L+ R + + + TPL+ + E L+ A N V
Sbjct: 94 ALHYAVYSENLSVVAKLLSRGADIQVKNKACLTPLLLVITKRSEEIVEFLVTKNASANAV 153
Query: 147 DVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKR 194
D + TA+ A+ +L V+ LL DI ++ G T A+ R
Sbjct: 154 DKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASR 201
Score = 32.0 bits (71), Expect = 0.58
Identities = 18/79 (22%), Positives = 35/79 (44%)
Query: 152 TAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKNTNANA 211
TA+H A ++ V+ L ++V++ TPL+ A++ E L+ + N
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREAYANILVDSGPSPNI 86
Query: 212 VDKFKCIHQQLLEYKQKIS 230
VD + + Y + +S
Sbjct: 87 VDVYGNMALHYAVYSENLS 105
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 189 bits (479), Expect = 3e-48
Identities = 92/170 (54%), Positives = 117/170 (68%)
Query: 83 VEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGAD 142
+ +TALH CANGH EVVT LVDRKCQL++ D ENRT LMKA QCQ E CA IL++ GAD
Sbjct: 79 MNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGAD 138
Query: 143 PNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFL 202
PN+ DV+GNTA+HYA+Y E++SV KLL A+IE KNK TPLLLA+ + +Q+VEFL
Sbjct: 139 PNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFL 198
Query: 203 LTKNTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPL 252
+ K N NAVDK + HQ + EYK++ + N E + D + L
Sbjct: 199 IKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDESSEDSLSRL 248
>gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo
sapiens]
Length = 452
Score = 169 bits (428), Expect = 2e-42
Identities = 87/188 (46%), Positives = 125/188 (66%), Gaps = 2/188 (1%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++TALH CANG++EVV+ L+DR+CQL + D + RT L+KA QCQ + CA +L+ G DP
Sbjct: 99 KRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDP 158
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
N+ D+YGNTA+HYA+Y E+ + LL GADIE KNK G TPLLLA+ + +++V+FL+
Sbjct: 159 NLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLI 218
Query: 204 TKNTNANAVDKFKCIHQQLLEYK--QKISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAE 261
K N NA+D+F I Q L +YK Q + +S NSNPE + T +E ++ + +
Sbjct: 219 KKKANLNALDRFGRICQLLSDYKENQMPNNSSGNSNPEQDLKLTSEEEPQRLKGSENSQH 278
Query: 262 SLVERTPD 269
V + PD
Sbjct: 279 EKVTQEPD 286
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 161 bits (408), Expect = 5e-40
Identities = 89/185 (48%), Positives = 126/185 (68%), Gaps = 11/185 (5%)
Query: 42 GSVNRIAKPSPGIRIYPSEDEKV---VIQGQ----KTCHIRVSLLMYAVEK---TALHWV 91
GS++ + S G RI SE +K+ ++G + C R S + A++K TALH
Sbjct: 16 GSIDHVYTGS-GYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLA 74
Query: 92 CANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNIVDVYGN 151
CA+GH +VVT LV+RKCQ+D+ D ENRTPL++A CQ E CA IL++ GA+PN+ D+YGN
Sbjct: 75 CASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGN 134
Query: 152 TAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKNTNANA 211
TA+HYA+Y E+ S+ KLLS GA IE +K +TPLL AI + E++VEFLL K +++A
Sbjct: 135 TALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHA 194
Query: 212 VDKFK 216
VD+ +
Sbjct: 195 VDRLR 199
Score = 56.6 bits (135), Expect = 2e-08
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 26/165 (15%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ + + L+ ++ LD +N TPL+ A C++E L+ A +
Sbjct: 135 TALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHA 194
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD +A+ A+Y ++ +V LL D+ ++ G R + + LTK
Sbjct: 195 VDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCG--------RDAEDYAISHHLTK 246
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAA 250
I QQ+LE+K+KI K E + G+ DE+A
Sbjct: 247 ------------IQQQILEHKKKILKK------EKSDVGSSDESA 273
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 160 bits (404), Expect = 1e-39
Identities = 88/185 (47%), Positives = 126/185 (68%), Gaps = 11/185 (5%)
Query: 42 GSVNRIAKPSPGIRIYPSEDEKV---VIQGQ----KTCHIRVSLLMYAVEK---TALHWV 91
GS++ + S G RI SE +K+ ++G + C R S + A++K TALH
Sbjct: 16 GSIDHVYTGS-GYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLA 74
Query: 92 CANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNIVDVYGN 151
CA+GH +VVT LV+RKCQ+D+ D ENRTPL++A CQ E CA IL++ GA+PN+ D+YGN
Sbjct: 75 CASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGN 134
Query: 152 TAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKNTNANA 211
TA+HYA+Y E+ S+ KLLS GA IE +K +TPLL AI + E++VEFLL + +++A
Sbjct: 135 TALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHA 194
Query: 212 VDKFK 216
VD+ +
Sbjct: 195 VDRLR 199
Score = 56.2 bits (134), Expect = 3e-08
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 26/165 (15%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ + + L+ ++ LD +N TPL+ A C++E L+ A +
Sbjct: 135 TALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHA 194
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD +A+ A+Y ++ +V LL D+ ++ G R + + LTK
Sbjct: 195 VDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCG--------RDAEDYAISHHLTK 246
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAA 250
I QQ+LE+K+KI K E + G+ DE+A
Sbjct: 247 ------------IQQQILEHKKKILKK------EKSDVGSSDESA 273
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 160 bits (404), Expect = 1e-39
Identities = 88/185 (47%), Positives = 126/185 (68%), Gaps = 11/185 (5%)
Query: 42 GSVNRIAKPSPGIRIYPSEDEKV---VIQGQ----KTCHIRVSLLMYAVEK---TALHWV 91
GS++ + S G RI SE +K+ ++G + C R S + A++K TALH
Sbjct: 16 GSIDHVYTGS-GYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLA 74
Query: 92 CANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNIVDVYGN 151
CA+GH +VVT LV+RKCQ+D+ D ENRTPL++A CQ E CA IL++ GA+PN+ D+YGN
Sbjct: 75 CASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGN 134
Query: 152 TAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKNTNANA 211
TA+HYA+Y E+ S+ KLLS GA IE +K +TPLL AI + E++VEFLL + +++A
Sbjct: 135 TALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHA 194
Query: 212 VDKFK 216
VD+ +
Sbjct: 195 VDRLR 199
Score = 56.2 bits (134), Expect = 3e-08
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 26/165 (15%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ + + L+ ++ LD +N TPL+ A C++E L+ A +
Sbjct: 135 TALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHA 194
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD +A+ A+Y ++ +V LL D+ ++ G R + + LTK
Sbjct: 195 VDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCG--------RDAEDYAISHHLTK 246
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAA 250
I QQ+LE+K+KI K E + G+ DE+A
Sbjct: 247 ------------IQQQILEHKKKILKK------EKSDVGSSDESA 273
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 159 bits (403), Expect = 2e-39
Identities = 88/185 (47%), Positives = 125/185 (67%), Gaps = 11/185 (5%)
Query: 42 GSVNRIAKPSPGIRIYPSEDEKV---VIQGQ----KTCHIRVSLLMYAVEK---TALHWV 91
GS++ + S G RI SE +K+ ++G + C R S + A++K TALH
Sbjct: 16 GSIDHVYTGS-GYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLA 74
Query: 92 CANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNIVDVYGN 151
C +GH +VVT LV+RKCQ+D+ D ENRTPL++A CQ E CA IL++ GA+PN+ D+YGN
Sbjct: 75 CTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGN 134
Query: 152 TAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKNTNANA 211
TA+HYA+Y E+ S+ KLLS GA IE +K +TPLL AI + E++VEFLL K +++A
Sbjct: 135 TALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHA 194
Query: 212 VDKFK 216
VD+ +
Sbjct: 195 VDRLR 199
Score = 56.6 bits (135), Expect = 2e-08
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 26/165 (15%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ + + L+ ++ LD +N TPL+ A C++E L+ A +
Sbjct: 135 TALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHA 194
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD +A+ A+Y ++ +V LL D+ ++ G R + + LTK
Sbjct: 195 VDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCG--------RDAEDYAISHHLTK 246
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAA 250
I QQ+LE+K+KI K E + G+ DE+A
Sbjct: 247 ------------IQQQILEHKKKILKK------EKSDVGSSDESA 273
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 157 bits (396), Expect = 1e-38
Identities = 76/133 (57%), Positives = 95/133 (71%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++T LH CA+G +VVT L+DRKCQ++I D NRTPLMKA CQ E CA IL+ GA+P
Sbjct: 167 DRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANP 226
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
NI D+YGNTA+HYA+Y E S+ +LLS A+IE NK G+TPLL AI R + +VEFLL
Sbjct: 227 NIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLL 286
Query: 204 TKNTNANAVDKFK 216
N +AVD FK
Sbjct: 287 KNQANIHAVDNFK 299
Score = 47.8 bits (112), Expect = 1e-05
Identities = 40/162 (24%), Positives = 68/162 (41%), Gaps = 20/162 (12%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + L+ ++ L+ E TPL+ A +R+ L+ + A+ +
Sbjct: 235 TALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHA 294
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD + TA+ A+ S+V LL I ++ G T
Sbjct: 295 VDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQ-------------------TA 335
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPD 247
A D + I QQ+LE+K K+ KN ++ + T+ P+
Sbjct: 336 EDYAFCCD-LRSIQQQILEHKNKMLKNHLRNDNQETAAMKPE 376
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 157 bits (396), Expect = 1e-38
Identities = 76/133 (57%), Positives = 95/133 (71%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++T LH CA+G +VVT L+DRKCQ++I D NRTPLMKA CQ E CA IL+ GA+P
Sbjct: 196 DRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANP 255
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
NI D+YGNTA+HYA+Y E S+ +LLS A+IE NK G+TPLL AI R + +VEFLL
Sbjct: 256 NIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLL 315
Query: 204 TKNTNANAVDKFK 216
N +AVD FK
Sbjct: 316 KNQANIHAVDNFK 328
Score = 47.8 bits (112), Expect = 1e-05
Identities = 40/162 (24%), Positives = 68/162 (41%), Gaps = 20/162 (12%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + L+ ++ L+ E TPL+ A +R+ L+ + A+ +
Sbjct: 264 TALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHA 323
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD + TA+ A+ S+V LL I ++ G T
Sbjct: 324 VDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQ-------------------TA 364
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPD 247
A D + I QQ+LE+K K+ KN ++ + T+ P+
Sbjct: 365 EDYAFCCD-LRSIQQQILEHKNKMLKNHLRNDNQETAAMKPE 405
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 157 bits (396), Expect = 1e-38
Identities = 76/133 (57%), Positives = 95/133 (71%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++T LH CA+G +VVT L+DRKCQ++I D NRTPLMKA CQ E CA IL+ GA+P
Sbjct: 196 DRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANP 255
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
NI D+YGNTA+HYA+Y E S+ +LLS A+IE NK G+TPLL AI R + +VEFLL
Sbjct: 256 NIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLL 315
Query: 204 TKNTNANAVDKFK 216
N +AVD FK
Sbjct: 316 KNQANIHAVDNFK 328
Score = 47.8 bits (112), Expect = 1e-05
Identities = 40/162 (24%), Positives = 68/162 (41%), Gaps = 20/162 (12%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + L+ ++ L+ E TPL+ A +R+ L+ + A+ +
Sbjct: 264 TALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHA 323
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD + TA+ A+ S+V LL I ++ G T
Sbjct: 324 VDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQ-------------------TA 364
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPD 247
A D + I QQ+LE+K K+ KN ++ + T+ P+
Sbjct: 365 EDYAFCCD-LRSIQQQILEHKNKMLKNHLRNDNQETAAMKPE 405
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 154 bits (389), Expect = 8e-38
Identities = 87/185 (47%), Positives = 123/185 (66%), Gaps = 11/185 (5%)
Query: 42 GSVNRIAKPSPGIRIYPSEDEKV---VIQGQ----KTCHIRVSLLMYAVEK---TALHWV 91
GS++ + S G RI SE +K+ ++G + C R S + A++K TALH
Sbjct: 16 GSIDHLYTGS-GYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLA 74
Query: 92 CANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNIVDVYGN 151
CA+GH +VVT LV+RKCQ+DI D ENRTPL++A CQ E CA IL++ GA+PN+ D+YGN
Sbjct: 75 CASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGN 134
Query: 152 TAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKNTNANA 211
TA+HYA+Y E+ S+ KLL G +IE +K +TPLL AI + E++VEFLL + +A
Sbjct: 135 TALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHA 194
Query: 212 VDKFK 216
VD+ +
Sbjct: 195 VDRLR 199
Score = 50.8 bits (120), Expect = 1e-06
Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 26/165 (15%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ + + L+ ++ LD ++ TPL+ A C++E L+ + A +
Sbjct: 135 TALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHA 194
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD TA+ A++ ++L +V LL ++ ++ G R + + LTK
Sbjct: 195 VDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCG--------RDAEDYAISCRLTK 246
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAA 250
I QQ+LE+K+ I KN + G+ DE+A
Sbjct: 247 ------------IQQQILEHKKMILKNDK------PDVGSSDESA 273
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 154 bits (389), Expect = 8e-38
Identities = 73/131 (55%), Positives = 98/131 (74%)
Query: 85 KTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPN 144
+TAL CA+G VV LV RKCQL++ D ENRT L+KA QCQ EVCA+IL++ GA+PN
Sbjct: 73 RTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPN 132
Query: 145 IVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLT 204
+ D+YGNTA+HYA+ EN+S+ KLL+ GADIE +++ GHT LLLA+ ++ EQ+V FLL
Sbjct: 133 VRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLK 192
Query: 205 KNTNANAVDKF 215
K + A+D F
Sbjct: 193 KKPDLTAIDNF 203
Score = 48.9 bits (115), Expect = 5e-06
Identities = 45/183 (24%), Positives = 73/183 (39%), Gaps = 25/183 (13%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + + L+ ++ + T L+ A ++E + L+ D
Sbjct: 140 TALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTA 199
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
+D +G TA+ A + SVV +LL D+ ++ +G T A+
Sbjct: 200 IDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAV-------------- 245
Query: 206 NTNANAVDKFKCIHQQLLEYK-QKISKNSQNSNPEG----TSEGTPDEAAPLVERTPDMA 260
KF+ I + EYK K K+ QNSN E TSEG + P +
Sbjct: 246 ------ASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVE 299
Query: 261 ESL 263
E +
Sbjct: 300 EKM 302
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 154 bits (389), Expect = 8e-38
Identities = 87/185 (47%), Positives = 123/185 (66%), Gaps = 11/185 (5%)
Query: 42 GSVNRIAKPSPGIRIYPSEDEKV---VIQGQ----KTCHIRVSLLMYAVEK---TALHWV 91
GS++ + S G RI SE +K+ ++G + C R S + A++K TALH
Sbjct: 16 GSIDHLYTGS-GYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLA 74
Query: 92 CANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNIVDVYGN 151
CA+GH +VVT LV+RKCQ+DI D ENRTPL++A CQ E CA IL++ GA+PN+ D+YGN
Sbjct: 75 CASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGN 134
Query: 152 TAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTKNTNANA 211
TA+HYA+Y E+ S+ KLL G +IE +K +TPLL AI + E++VEFLL + +A
Sbjct: 135 TALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHA 194
Query: 212 VDKFK 216
VD+ +
Sbjct: 195 VDRLR 199
Score = 50.8 bits (120), Expect = 1e-06
Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 26/165 (15%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ + + L+ ++ LD ++ TPL+ A C++E L+ + A +
Sbjct: 135 TALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHA 194
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD TA+ A++ ++L +V LL ++ ++ G R + + LTK
Sbjct: 195 VDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCG--------RDAEDYAISCRLTK 246
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAA 250
I QQ+LE+K+ I KN + G+ DE+A
Sbjct: 247 ------------IQQQILEHKKMILKNDK------PDVGSSDESA 273
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 154 bits (389), Expect = 8e-38
Identities = 73/131 (55%), Positives = 98/131 (74%)
Query: 85 KTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPN 144
+TAL CA+G VV LV RKCQL++ D ENRT L+KA QCQ EVCA+IL++ GA+PN
Sbjct: 73 RTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPN 132
Query: 145 IVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLT 204
+ D+YGNTA+HYA+ EN+S+ KLL+ GADIE +++ GHT LLLA+ ++ EQ+V FLL
Sbjct: 133 VRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLK 192
Query: 205 KNTNANAVDKF 215
K + A+D F
Sbjct: 193 KKPDLTAIDNF 203
Score = 48.9 bits (115), Expect = 5e-06
Identities = 45/183 (24%), Positives = 73/183 (39%), Gaps = 25/183 (13%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + + L+ ++ + T L+ A ++E + L+ D
Sbjct: 140 TALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTA 199
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
+D +G TA+ A + SVV +LL D+ ++ +G T A+
Sbjct: 200 IDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAV-------------- 245
Query: 206 NTNANAVDKFKCIHQQLLEYK-QKISKNSQNSNPEG----TSEGTPDEAAPLVERTPDMA 260
KF+ I + EYK K K+ QNSN E TSEG + P +
Sbjct: 246 ------ASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVE 299
Query: 261 ESL 263
E +
Sbjct: 300 EKM 302
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 154 bits (388), Expect = 1e-37
Identities = 73/131 (55%), Positives = 98/131 (74%)
Query: 85 KTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPN 144
+TAL CA+G VV LV RKCQL++ D ENRT L+KA QCQ EVCA+IL++ GA+PN
Sbjct: 73 RTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPN 132
Query: 145 IVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLT 204
+ D+YGNTA+HYA+ EN+S+ KLL+ GADIE +++ GHT LLLA+ ++ EQ+V FLL
Sbjct: 133 VRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLK 192
Query: 205 KNTNANAVDKF 215
K + A+D F
Sbjct: 193 KKPDLTAIDNF 203
Score = 47.8 bits (112), Expect = 1e-05
Identities = 45/183 (24%), Positives = 72/183 (39%), Gaps = 25/183 (13%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + + L+ ++ + T L+ A ++E L+ D
Sbjct: 140 TALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTA 199
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
+D +G TA+ A + SVV +LL D+ ++ +G T A+
Sbjct: 200 IDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAV-------------- 245
Query: 206 NTNANAVDKFKCIHQQLLEYK-QKISKNSQNSNPEG----TSEGTPDEAAPLVERTPDMA 260
KF+ I + EYK K K+ QNSN E TSEG + P +
Sbjct: 246 ------ASKFQAIRGMISEYKANKRCKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVE 299
Query: 261 ESL 263
E +
Sbjct: 300 EKM 302
>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
sapiens]
Length = 498
Score = 151 bits (382), Expect = 5e-37
Identities = 70/132 (53%), Positives = 98/132 (74%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++TALH CANG++EVV+ L+DR+CQL + D + RT L+KA QCQ + CA +L+ G DP
Sbjct: 99 KRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDP 158
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
N+ D+YGNTA+HYA+Y E+ + LL GADIE KNK G TPLLLA+ + +++V+FL+
Sbjct: 159 NLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLI 218
Query: 204 TKNTNANAVDKF 215
K N NA+D+F
Sbjct: 219 KKKANLNALDRF 230
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 150 bits (379), Expect = 1e-36
Identities = 72/133 (54%), Positives = 94/133 (70%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++T LH CA+G +VVT L+ R+CQ+DI D NRTPLMKA Q E CA +L++ GA+P
Sbjct: 175 DRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANP 234
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
NI D+YGNTA+HYA+Y + S+ +LLS A+IE NK G+TPLL AI R + +VEFLL
Sbjct: 235 NIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLL 294
Query: 204 TKNTNANAVDKFK 216
N +AVD FK
Sbjct: 295 KNQANIHAVDNFK 307
Score = 48.5 bits (114), Expect = 6e-06
Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 20/170 (11%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + L+ ++ L+ E TPL+ A +R+ L+ + A+ +
Sbjct: 243 TALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHA 302
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD + TA+ A+ S+V LL I ++ G T A+
Sbjct: 303 VDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYAL-------------- 348
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVER 255
+ I QQ+LE+K K+ KN ++ + T+ P ER
Sbjct: 349 ------CSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKER 392
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 150 bits (379), Expect = 1e-36
Identities = 72/133 (54%), Positives = 94/133 (70%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++T LH CA+G +VVT L+ R+CQ+DI D NRTPLMKA Q E CA +L++ GA+P
Sbjct: 68 DRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANP 127
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
NI D+YGNTA+HYA+Y + S+ +LLS A+IE NK G+TPLL AI R + +VEFLL
Sbjct: 128 NIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLL 187
Query: 204 TKNTNANAVDKFK 216
N +AVD FK
Sbjct: 188 KNQANIHAVDNFK 200
Score = 48.5 bits (114), Expect = 6e-06
Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 20/170 (11%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + L+ ++ L+ E TPL+ A +R+ L+ + A+ +
Sbjct: 136 TALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHA 195
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD + TA+ A+ S+V LL I ++ G T A+
Sbjct: 196 VDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYAL-------------- 241
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVER 255
+ I QQ+LE+K K+ KN ++ + T+ P ER
Sbjct: 242 ------CSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKER 285
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 150 bits (379), Expect = 1e-36
Identities = 72/133 (54%), Positives = 94/133 (70%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++T LH CA+G +VVT L+ R+CQ+DI D NRTPLMKA Q E CA +L++ GA+P
Sbjct: 175 DRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANP 234
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
NI D+YGNTA+HYA+Y + S+ +LLS A+IE NK G+TPLL AI R + +VEFLL
Sbjct: 235 NIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLL 294
Query: 204 TKNTNANAVDKFK 216
N +AVD FK
Sbjct: 295 KNQANIHAVDNFK 307
Score = 48.5 bits (114), Expect = 6e-06
Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 20/170 (11%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + L+ ++ L+ E TPL+ A +R+ L+ + A+ +
Sbjct: 243 TALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHA 302
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
VD + TA+ A+ S+V LL I ++ G T A+
Sbjct: 303 VDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYAL-------------- 348
Query: 206 NTNANAVDKFKCIHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVER 255
+ I QQ+LE+K K+ KN ++ + T+ P ER
Sbjct: 349 ------CSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKER 392
>gi|224282147 prostate-specific P704P [Homo sapiens]
Length = 508
Score = 150 bits (378), Expect = 1e-36
Identities = 71/132 (53%), Positives = 97/132 (73%)
Query: 84 EKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADP 143
++TALH ANG++EVV L+DR+CQL+ILD + RT L KA QCQ + CA +L++ G DP
Sbjct: 173 KRTALHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDP 232
Query: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
NI D YGNTA+HYA+Y E+ + LL GADIE KNK G TPLLL + ++ +Q+V+FL+
Sbjct: 233 NIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLI 292
Query: 204 TKNTNANAVDKF 215
K N NA+D++
Sbjct: 293 KKKANLNALDRY 304
Score = 50.1 bits (118), Expect = 2e-06
Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 22/186 (11%)
Query: 86 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 145
TALH+ N + L+ ++ + TPL+ Q++ LI A+ N
Sbjct: 241 TALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNA 300
Query: 146 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 205
+D YG T + A+ + S+V+ LL D+ ++ +G T A+ R I
Sbjct: 301 LDRYGRTVLILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVIC------ 354
Query: 206 NTNANAVDKFKCIHQQLLEYKQK--ISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESL 263
Q L +YK+K + +S+NSNPE + T +E + ++ + +
Sbjct: 355 --------------QLLSDYKEKQILKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEE 400
Query: 264 VERTPD 269
+ + P+
Sbjct: 401 MSQEPE 406
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,929,684
Number of Sequences: 37866
Number of extensions: 490903
Number of successful extensions: 3704
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 321
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 1482
Number of HSP's gapped (non-prelim): 1597
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.